id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-031033-v4yetn4f	Martin-Loeches, Ignacio	The importance of airway and lung microbiome in the critically ill	2020-08-31		.txt	text/plain	5110	235	27	In this narrative review, we will focus on the rationale and current evidence for a pathogenic role of the lung microbiome in the exacerbation of complications of critical illness, such as acute respiratory distress syndrome and ventilator-associated pneumonia. In this narrative review, we will focus on the rationale and current evidence for a pathogenic role of the lung microbiome in the exacerbation of complications of critical illness, such as acute respiratory distress syndrome (ARDS) and ventilator-associated pneumonia (VAP). This study found that a single streamlined protocol offering an integrated genomic portrait of pathogen, microbiome and host transcriptome represents a new tool for diagnosis in lower respiratory tract infections (LRTI). Alternatively, the mere onset of critical illness-be it sepsis, ARDS or any number of conditions, is associated with alterations of the gut Fig. 2 Island model for the development of lung injury based on sites of dysbiosis microbiome, which may be independent of antibiotic administration [61] .	./cache/cord-031033-v4yetn4f.txt	./txt/cord-031033-v4yetn4f.txt