id author title date pages extension mime words sentences flesch summary cache txt cord-102679-6dpo073b TRONCHE, P.-A. Assessment of a Novel Method for Non-invasive Sampling of the Distal Airspace in Acute Respiratory Distress Syndrome Patients Receiving Inhaled Sedation with Sevoflurane: the ANAISS Study Protocol 2020-10-07 .txt text/plain 5172 282 47 title: Assessment of a Novel Method for Non-invasive Sampling of the Distal Airspace in Acute Respiratory Distress Syndrome Patients Receiving Inhaled Sedation with Sevoflurane: the ANAISS Study Protocol Therefore, collection of this fluid represents a promising, non-invasive method for sampling the distal airspace in patients with acute respiratory distress syndrome (ARDS) and for facilitating a mechanistic understanding of this devastating disease. Methods and analysis: A total of 30 adult patients within 24 hours of meeting the Berlin criteria for moderate-severe ARDS and receiving inhaled sevoflurane as standard sedation in participating centres will be eligible for inclusion into this investigator-initiated, exploratory, prospective, bicentre study. The primary hypothesis of the ANAISS study is that fluid collection from the AnaConDa-S device could be a novel method for assessing the distal airspace in mechanically ventilated patients with ARDS who are receiving inhaled sedation with sevoflurane. ./cache/cord-102679-6dpo073b.txt ./txt/cord-102679-6dpo073b.txt