id author title date pages extension mime words sentences flesch summary cache txt cord-308402-37i62atc Barnes, Betsy J. Targeting potential drivers of COVID-19: Neutrophil extracellular traps 2020-04-16 .txt text/plain 3924 253 43 In this Perspective, autopsy results and literature are presented supporting the hypothesis that a little known yet powerful function of neutrophils—the ability to form neutrophil extracellular traps (NETs)—may contribute to organ damage and mortality in COVID-19. Furthermore, neutrophils from patients with pneumonia-associated ARDS appear "primed" to form NETs, and both the extent of priming and the level of NETs in blood correlate with disease severity and mortality (Adrover et al., 2020; Bendib et al., 2019; Ebrahimi et al., 2018; Lefrançais et al., 2018; Mikacenic et al., 2018) . NETs and excessive thrombosis Acute cardiac and kidney injuries are common in patients with severe COVID-19 and contribute to the mortality of this disease (Bonow et al., 2020) . Neutrophil extracellular traps (NETs) are increased in the alveolar spaces of patients with ventilator-associated pneumonia ./cache/cord-308402-37i62atc.txt ./txt/cord-308402-37i62atc.txt