id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-315093-ifeulv55	Longobardo, Alessia	Inhaled nitric oxide produces minimal improvement in oxygenation in COVID-19 related ARDS	2020-10-14		.txt	text/plain	827	59	51	Baseline PaO 2 : FiO 2 ratio, dose of iNO, use of steroid, prone position ventilation, C-reactive protein, D-dimer levels, N-terminal B-type natriuretic peptide (NT-BNP) levels, fluid balance, driving pressure, days from ICU admission to iNO, pulmonary compliance, diagnosis of VTE, or body mass index did not discriminate between COVID-19 patients who responded to iNO or not (Supplementary Figure 1) . 5 However, we found that the increase in PaO 2 :FiO 2 ratio in COVID-19 ARDS patients in response to iNO was significantly lower compared to ARDS patients without ARDS, consistent with another published series. 4, 7 In contrast, patients with coronavirus-related SARS, where increased thrombosis was not a hallmark, demonstrated significant PaO 2 :FiO 2 ratio improvements in response to iNO. In summary, more than half of patients with refractory hypoxaemia secondary to COVID-19 ARDS did not show an increase in PaO 2 :FiO 2 ratio in response to iNO.	./cache/cord-315093-ifeulv55.txt	./txt/cord-315093-ifeulv55.txt