id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-316056-lk2upygf	Lepper, Philipp M.	Mechanical ventilation in early COVID-19 ARDS	2020-11-06		.txt	text/plain	939	63	55	As published in EClinicalMedicine, Mittermaier and colleagues [2] investigated the effects of IMV, positive end-expiratory pressure (PEEP) and prone positioning (PP) on oxygenation and lung recruitability in patients with COVID-19-related ARDS (CARDS). PEEP has been used in the first description of ARDS and led to an increase in P a O 2 or oxygen saturation in five of the twelve initial patients treated this way [3] . In the present study, pulmonary compliance was relatively preserved but increasing FRC by high PEEP levels led to significantly improved oxygenation. The present study does not answer the question of whether PEEP applied by non-invasive ventilation (NIV) can improve oxygenation in a similar way as IMV. Oxygenation response to positive end-expiratory pressure predicts mortality in acute respiratory distress syndrome. lower positive end-expiratory pressure in patients with acute lung injury and acute respiratory distress syndrome: systematic review and meta-analysis Prone position improves mechanics and alveolar ventilation in acute respiratory distress syndrome	./cache/cord-316056-lk2upygf.txt	./txt/cord-316056-lk2upygf.txt