id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-316923-b81uaooh	Luks, Andrew M.	Reply: COVID-19 Lung Injury and “Typical” Acute Respiratory Distress Syndrome: The Danger of Presumed Equivalency	2020-09-17		.txt	text/plain	1531	75	46	For example, in COVID-19 lung disease, a hypoxemic condition that progresses over several days in which many patients do not appear to be in distress, what is more injurious: accepting a lower oxygen saturation as measured by pulse oximetry or initiating invasive mechanical ventilation? With great respect for the authors' well-meaning concern to avoid patient harm, let me be clear about mine: I am concerned that the alveolar filling/collapse, low-compliance pulmonary disease being seen in the intensive care unit is predominantly due to ventilator-induced lung injury rather than to the natural evolution of COVID-19 disease. Finally, the author states, without supporting evidence, that patients with COVID-19 have "normal or near-normal pulmonary compliance." To date, only three published reports have documented static compliance in COVID-19, and in two of them (2, 3) the average static compliance was low (,35 ml/cm H 2 O) and consistent with that seen in prior studies of ARDS.	./cache/cord-316923-b81uaooh.txt	./txt/cord-316923-b81uaooh.txt