id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-325461-q8igdvq4	Ryan, Donal	Pulmonary vascular dysfunction in ARDS	2014-08-22		.txt	text/plain	6627	348	42	We consider the factors that influence pulmonary arterial pressure, both in normal lungs and in the presence of ARDS, including the important effects of mechanical ventilation. (Am J Respir Crit Care Med 182:1123–1128, 2010) have recently reported that elevated pulmonary vascular resistance (PVR) and TPG were independently associated with increased mortality in ARDS, in a large trial with protocol-defined management strategies and using lung-protective ventilation. Studies were identified after a literature search using key terms (ARDS or acute respiratory distress or ALI or acute lung injury) together with any of the following: pulmonary haemodynamics, pulmonary artery pressure, pulmonary vascular resistance, pulmonary vascular dysfunction, right ventricle, right ventricular failure, acute cor pulmonale, or pulmonary artery catheter. There are very few studies which have measured pulmonary vascular resistance in ARDS patients ventilated with lower tidal volumes, perhaps due to the reduction in the use of the pulmonary artery catheter just as lung-protective ventilation was gaining widespread acceptance [60] .	./cache/cord-325461-q8igdvq4.txt	./txt/cord-325461-q8igdvq4.txt