id author title date pages extension mime words sentences flesch summary cache txt cord-328996-3sf2i45r Barthélémy, Romain Efficacy of Almitrine in The Treatment of Hypoxemia in Sars-Cov-2 Acute Respiratory Distress Syndrome 2020-06-06 .txt text/plain 1161 100 59 title: Efficacy of Almitrine in The Treatment of Hypoxemia in Sars-Cov-2 Acute Respiratory Distress Syndrome This monocenter retrospective study aimed to evaluate the association between almitrine 19 introduction and improvement of oxygenation in Sars-Cov-2 ARDS. Inclusion criteria in the study were: admission for respiratory failure, a diagnosis of ARDS 24 according to Berlin criteria 8 , laboratory confirmed Sars-Cov-2 infection, almitrine infusion in 25 ICU. In our 73 observational study, almitrine was associated with an increase in PaO 2 /FiO 2 ratio after 74 treatment. Furthermore, despite an associated improvement in PaO 2 /FiO 2 ratio, the majority 76 of patients receiving almitrine went on to needing additional rescue interventions or died. 77 This may be explained by the fact that, in our study, almitrine has been used as a rescue 78 therapy in severe patients with worsening hypoxemia and very low PaO 2 /FiO 2 ratio. ./cache/cord-328996-3sf2i45r.txt ./txt/cord-328996-3sf2i45r.txt