id author title date pages extension mime words sentences flesch summary cache txt cord-335977-f00758o2 Martin-Loeches, I. Use of early corticosteroid therapy on ICU admission in patients affected by severe pandemic (H1N1)v influenza A infection 2010-11-24 .txt text/plain 4300 258 42 title: Use of early corticosteroid therapy on ICU admission in patients affected by severe pandemic (H1N1)v influenza A infection Recent guidelines for management of human infection with pandemic (H1N1)v influenza A infection recommend that corticosteroid therapy should not be used routinely, although low doses may be considered for patients in septic shock who require vasopressors and have suspected adrenal insufficiency [15, 16] . The main objective of this study is therefore to assess the effect on survival of early corticosteroid therapy compared with those who did not receive corticosteroids or received them subsequently as rescue therapy, in a cohort of patients hospitalized with severe presentation of pandemic (H1N1)v influenza A infection in the ICU. This analysis of a large, cohort, prospective, multicenter research study suggests that prompt use of corticosteroid therapy on ICU admission does not result in a reduction of mortality for critically ill patients admitted with pandemic (H1N1)v influenza A infection. ./cache/cord-335977-f00758o2.txt ./txt/cord-335977-f00758o2.txt