id author title date pages extension mime words sentences flesch summary cache txt cord-349197-3trr8d0u Ventura, Francesco Two Fatal Cases of Hidden Pneumonia in Young People 2010-04-28 .txt text/plain 2503 137 40 In both cases the cause of death was cardio‐respiratory failure following an acute bilateral pneumonia with diffuse alveolar damage and ARDS associated with sepsis and disseminated intravascular coagulation. Our cases suggest on one side the importance of an early diagnosis to avoid unexpected death while on the other that the diagnosis of ARDS has to be confirmed on the basis of a careful postmortem examination and a complete microscopy and microbiological study. Acute respiratory distress syndrome (ARDS) is a severe lung disease characterized by inflammation of the lung parenchyma leading to impaired gas exchange with concomitant systemic release of inflammatory mediators by local epithelial and endothelial cells, causing inflammation, hypoxemia resulting often in multiple organ failure (MOF), and disseminate intravascular coagulation (DIC) (1) . The clinical presentation, the radiological and laboratory findings in one case, and the postmortem examination with histological, immunohistochemical, and microbiological exams in both cases, led us to conclude for an acute cardio-respiratory failure secondary to bilateral pneumonia with DAD and consequently ARDS associated with sepsis and DIC. ./cache/cord-349197-3trr8d0u.txt ./txt/cord-349197-3trr8d0u.txt