id sid tid token lemma pos cord-025920-9p5x26ge 1 1 key key NN cord-025920-9p5x26ge 1 2 : : : cord-025920-9p5x26ge 2 1 cord-025920 cord-025920 NNP cord-025920-9p5x26ge 2 2 - - HYPH cord-025920-9p5x26ge 2 3 9p5x26ge 9p5x26ge CD cord-025920-9p5x26ge 2 4 authors author NNS cord-025920-9p5x26ge 2 5 : : : cord-025920-9p5x26ge 2 6 Qadir Qadir NNP cord-025920-9p5x26ge 2 7 , , , cord-025920-9p5x26ge 2 8 Nida Nida NNP cord-025920-9p5x26ge 2 9 ; ; : cord-025920-9p5x26ge 2 10 Chen Chen NNP cord-025920-9p5x26ge 2 11 , , , cord-025920-9p5x26ge 2 12 Jen Jen NNP cord-025920-9p5x26ge 2 13 - - HYPH cord-025920-9p5x26ge 2 14 Ting Ting NNP cord-025920-9p5x26ge 2 15 title title NN cord-025920-9p5x26ge 2 16 : : : cord-025920-9p5x26ge 2 17 Adjunctive Adjunctive NNP cord-025920-9p5x26ge 2 18 Therapies Therapies NNP cord-025920-9p5x26ge 2 19 in in IN cord-025920-9p5x26ge 2 20 ARDS ARDS NNP cord-025920-9p5x26ge 2 21 : : : cord-025920-9p5x26ge 3 1 The the DT cord-025920-9p5x26ge 3 2 Disconnect disconnect NN cord-025920-9p5x26ge 3 3 Between between IN cord-025920-9p5x26ge 3 4 Clinical Clinical NNP cord-025920-9p5x26ge 3 5 Trials Trials NNPS cord-025920-9p5x26ge 3 6 and and CC cord-025920-9p5x26ge 3 7 Clinical Clinical NNP cord-025920-9p5x26ge 3 8 Practice Practice NNP cord-025920-9p5x26ge 3 9 date date NN cord-025920-9p5x26ge 3 10 : : : cord-025920-9p5x26ge 3 11 2020 2020 CD cord-025920-9p5x26ge 3 12 - - HYPH cord-025920-9p5x26ge 3 13 06 06 CD cord-025920-9p5x26ge 3 14 - - HYPH cord-025920-9p5x26ge 3 15 03 03 CD cord-025920-9p5x26ge 3 16 journal journal NN cord-025920-9p5x26ge 3 17 : : : cord-025920-9p5x26ge 4 1 Chest chest NN cord-025920-9p5x26ge 4 2 DOI DOI NNP cord-025920-9p5x26ge 4 3 : : : cord-025920-9p5x26ge 4 4 10.1016 10.1016 CD cord-025920-9p5x26ge 4 5 / / SYM cord-025920-9p5x26ge 4 6 j.chest.2020.03.022 j.chest.2020.03.022 NN cord-025920-9p5x26ge 4 7 sha sha NNP cord-025920-9p5x26ge 4 8 : : : cord-025920-9p5x26ge 5 1 620afecf50c1a916b799b4a391e55d9b01819957 620afecf50c1a916b799b4a391e55d9b01819957 CD cord-025920-9p5x26ge 5 2 doc_id doc_id CD cord-025920-9p5x26ge 5 3 : : : cord-025920-9p5x26ge 6 1 25920 25920 CD cord-025920-9p5x26ge 6 2 cord_uid cord_uid NNS cord-025920-9p5x26ge 6 3 : : : cord-025920-9p5x26ge 6 4 9p5x26ge 9p5x26ge CD cord-025920-9p5x26ge 7 1 nan nan NNP cord-025920-9p5x26ge 7 2 Nearly nearly RB cord-025920-9p5x26ge 7 3 20 20 CD cord-025920-9p5x26ge 7 4 years year NNS cord-025920-9p5x26ge 7 5 have have VBP cord-025920-9p5x26ge 7 6 passed pass VBN cord-025920-9p5x26ge 7 7 since since IN cord-025920-9p5x26ge 7 8 the the DT cord-025920-9p5x26ge 7 9 advent advent NN cord-025920-9p5x26ge 7 10 of of IN cord-025920-9p5x26ge 7 11 low low JJ cord-025920-9p5x26ge 7 12 tidal tidal JJ cord-025920-9p5x26ge 7 13 volume volume NN cord-025920-9p5x26ge 7 14 ventilation ventilation NN cord-025920-9p5x26ge 7 15 , , , cord-025920-9p5x26ge 7 16 1 1 CD cord-025920-9p5x26ge 7 17 yet yet RB cord-025920-9p5x26ge 7 18 the the DT cord-025920-9p5x26ge 7 19 mortality mortality NN cord-025920-9p5x26ge 7 20 for for IN cord-025920-9p5x26ge 7 21 patients patient NNS cord-025920-9p5x26ge 7 22 with with IN cord-025920-9p5x26ge 7 23 ARDS ARDS NNP cord-025920-9p5x26ge 7 24 remains remain VBZ cord-025920-9p5x26ge 7 25 high high JJ cord-025920-9p5x26ge 7 26 . . . cord-025920-9p5x26ge 8 1 Revisiting revisit VBG cord-025920-9p5x26ge 8 2 the the DT cord-025920-9p5x26ge 8 3 treatment treatment NN cord-025920-9p5x26ge 8 4 modalities modality NNS cord-025920-9p5x26ge 8 5 used use VBD cord-025920-9p5x26ge 8 6 to to TO cord-025920-9p5x26ge 8 7 manage manage VB cord-025920-9p5x26ge 8 8 this this DT cord-025920-9p5x26ge 8 9 syndrome syndrome NN cord-025920-9p5x26ge 8 10 has have VBZ cord-025920-9p5x26ge 8 11 become become VBN cord-025920-9p5x26ge 8 12 increasingly increasingly RB cord-025920-9p5x26ge 8 13 important important JJ cord-025920-9p5x26ge 8 14 in in IN cord-025920-9p5x26ge 8 15 light light NN cord-025920-9p5x26ge 8 16 of of IN cord-025920-9p5x26ge 8 17 the the DT cord-025920-9p5x26ge 8 18 COVID-19 COVID-19 NNP cord-025920-9p5x26ge 8 19 pandemic pandemic NN cord-025920-9p5x26ge 8 20 . . . cord-025920-9p5x26ge 9 1 Although although IN cord-025920-9p5x26ge 9 2 ventilator ventilator NN cord-025920-9p5x26ge 9 3 management management NN cord-025920-9p5x26ge 9 4 comprises comprise VBZ cord-025920-9p5x26ge 9 5 a a DT cord-025920-9p5x26ge 9 6 large large JJ cord-025920-9p5x26ge 9 7 component component NN cord-025920-9p5x26ge 9 8 of of IN cord-025920-9p5x26ge 9 9 ARDS ARDS NNP cord-025920-9p5x26ge 9 10 care care NN cord-025920-9p5x26ge 9 11 , , , cord-025920-9p5x26ge 9 12 adjunctive adjunctive JJ cord-025920-9p5x26ge 9 13 , , , cord-025920-9p5x26ge 9 14 nonventilator nonventilator NNP cord-025920-9p5x26ge 9 15 therapies therapy NNS cord-025920-9p5x26ge 9 16 also also RB cord-025920-9p5x26ge 9 17 make make VBP cord-025920-9p5x26ge 9 18 up up RP cord-025920-9p5x26ge 9 19 an an DT cord-025920-9p5x26ge 9 20 important important JJ cord-025920-9p5x26ge 9 21 part part NN cord-025920-9p5x26ge 9 22 of of IN cord-025920-9p5x26ge 9 23 a a DT cord-025920-9p5x26ge 9 24 clinician clinician NN cord-025920-9p5x26ge 9 25 's 's POS cord-025920-9p5x26ge 9 26 toolkit toolkit NN cord-025920-9p5x26ge 9 27 . . . cord-025920-9p5x26ge 10 1 Over over IN cord-025920-9p5x26ge 10 2 the the DT cord-025920-9p5x26ge 10 3 years year NNS cord-025920-9p5x26ge 10 4 , , , cord-025920-9p5x26ge 10 5 a a DT cord-025920-9p5x26ge 10 6 number number NN cord-025920-9p5x26ge 10 7 of of IN cord-025920-9p5x26ge 10 8 studies study NNS cord-025920-9p5x26ge 10 9 on on IN cord-025920-9p5x26ge 10 10 adjunctive adjunctive JJ cord-025920-9p5x26ge 10 11 therapies therapy NNS cord-025920-9p5x26ge 10 12 for for IN cord-025920-9p5x26ge 10 13 ARDS ARDS NNP cord-025920-9p5x26ge 10 14 2 2 CD cord-025920-9p5x26ge 10 15 have have VBP cord-025920-9p5x26ge 10 16 been be VBN cord-025920-9p5x26ge 10 17 conducted conduct VBN cord-025920-9p5x26ge 10 18 , , , cord-025920-9p5x26ge 10 19 but but CC cord-025920-9p5x26ge 10 20 their -PRON- PRP$ cord-025920-9p5x26ge 10 21 implementation implementation NN cord-025920-9p5x26ge 10 22 and and CC cord-025920-9p5x26ge 10 23 impact impact NN cord-025920-9p5x26ge 10 24 as as IN cord-025920-9p5x26ge 10 25 a a DT cord-025920-9p5x26ge 10 26 whole whole NN cord-025920-9p5x26ge 10 27 on on IN cord-025920-9p5x26ge 10 28 patient patient JJ cord-025920-9p5x26ge 10 29 outcomes outcome NNS cord-025920-9p5x26ge 10 30 are be VBP cord-025920-9p5x26ge 10 31 unclear unclear JJ cord-025920-9p5x26ge 10 32 . . . cord-025920-9p5x26ge 11 1 In in IN cord-025920-9p5x26ge 11 2 this this DT cord-025920-9p5x26ge 11 3 issue issue NN cord-025920-9p5x26ge 11 4 of of IN cord-025920-9p5x26ge 11 5 CHEST chest NN cord-025920-9p5x26ge 11 6 , , , cord-025920-9p5x26ge 11 7 Duggal Duggal NNP cord-025920-9p5x26ge 11 8 et et FW cord-025920-9p5x26ge 11 9 al al NNP cord-025920-9p5x26ge 11 10 2 2 CD cord-025920-9p5x26ge 11 11 set set VBD cord-025920-9p5x26ge 11 12 out out RP cord-025920-9p5x26ge 11 13 to to TO cord-025920-9p5x26ge 11 14 address address VB cord-025920-9p5x26ge 11 15 an an DT cord-025920-9p5x26ge 11 16 important important JJ cord-025920-9p5x26ge 11 17 issue issue NN cord-025920-9p5x26ge 11 18 : : : cord-025920-9p5x26ge 11 19 the the DT cord-025920-9p5x26ge 11 20 use use NN cord-025920-9p5x26ge 11 21 of of IN cord-025920-9p5x26ge 11 22 adjunctive adjunctive JJ cord-025920-9p5x26ge 11 23 therapies therapy NNS cord-025920-9p5x26ge 11 24 in in IN cord-025920-9p5x26ge 11 25 patients patient NNS cord-025920-9p5x26ge 11 26 with with IN cord-025920-9p5x26ge 11 27 moderate moderate JJ cord-025920-9p5x26ge 11 28 to to IN cord-025920-9p5x26ge 11 29 severe severe JJ cord-025920-9p5x26ge 11 30 ARDS ARDS NNP cord-025920-9p5x26ge 11 31 , , , cord-025920-9p5x26ge 11 32 a a DT cord-025920-9p5x26ge 11 33 timely timely JJ cord-025920-9p5x26ge 11 34 subject subject NN cord-025920-9p5x26ge 11 35 in in IN cord-025920-9p5x26ge 11 36 the the DT cord-025920-9p5x26ge 11 37 setting setting NN cord-025920-9p5x26ge 11 38 of of IN cord-025920-9p5x26ge 11 39 COVID-19 covid-19 NN cord-025920-9p5x26ge 11 40 . . . cord-025920-9p5x26ge 12 1 Their -PRON- PRP$ cord-025920-9p5x26ge 12 2 objectives objective NNS cord-025920-9p5x26ge 12 3 were be VBD cord-025920-9p5x26ge 12 4 to to TO cord-025920-9p5x26ge 12 5 evaluate evaluate VB cord-025920-9p5x26ge 12 6 the the DT cord-025920-9p5x26ge 12 7 frequency frequency NN cord-025920-9p5x26ge 12 8 and and CC cord-025920-9p5x26ge 12 9 patterns pattern NNS cord-025920-9p5x26ge 12 10 of of IN cord-025920-9p5x26ge 12 11 use use NN cord-025920-9p5x26ge 12 12 of of IN cord-025920-9p5x26ge 12 13 adjunctive adjunctive JJ cord-025920-9p5x26ge 12 14 therapies therapy NNS cord-025920-9p5x26ge 12 15 in in IN cord-025920-9p5x26ge 12 16 this this DT cord-025920-9p5x26ge 12 17 patient patient JJ cord-025920-9p5x26ge 12 18 population population NN cord-025920-9p5x26ge 12 19 , , , cord-025920-9p5x26ge 12 20 as as RB cord-025920-9p5x26ge 12 21 well well RB cord-025920-9p5x26ge 12 22 as as IN cord-025920-9p5x26ge 12 23 to to TO cord-025920-9p5x26ge 12 24 understand understand VB cord-025920-9p5x26ge 12 25 the the DT cord-025920-9p5x26ge 12 26 factors factor NNS cord-025920-9p5x26ge 12 27 associated associate VBN cord-025920-9p5x26ge 12 28 with with IN cord-025920-9p5x26ge 12 29 the the DT cord-025920-9p5x26ge 12 30 use use NN cord-025920-9p5x26ge 12 31 of of IN cord-025920-9p5x26ge 12 32 these these DT cord-025920-9p5x26ge 12 33 therapies therapy NNS cord-025920-9p5x26ge 12 34 . . . cord-025920-9p5x26ge 13 1 Although although IN cord-025920-9p5x26ge 13 2 the the DT cord-025920-9p5x26ge 13 3 Large Large NNP cord-025920-9p5x26ge 13 4 Observational Observational NNP cord-025920-9p5x26ge 13 5 Study Study NNP cord-025920-9p5x26ge 13 6 to to TO cord-025920-9p5x26ge 13 7 Understand understand VB cord-025920-9p5x26ge 13 8 the the DT cord-025920-9p5x26ge 13 9 Global Global NNP cord-025920-9p5x26ge 13 10 Impact Impact NNP cord-025920-9p5x26ge 13 11 of of IN cord-025920-9p5x26ge 13 12 Severe severe JJ cord-025920-9p5x26ge 13 13 Acute acute JJ cord-025920-9p5x26ge 13 14 Respiratory respiratory JJ cord-025920-9p5x26ge 13 15 Failure failure NN cord-025920-9p5x26ge 14 1 ( ( -LRB- cord-025920-9p5x26ge 14 2 LUNG lung NN cord-025920-9p5x26ge 14 3 - - HYPH cord-025920-9p5x26ge 14 4 SAFE SAFE NNP cord-025920-9p5x26ge 14 5 ) ) -RRB- cord-025920-9p5x26ge 15 1 previously previously RB cord-025920-9p5x26ge 15 2 assessed assess VBD cord-025920-9p5x26ge 15 3 the the DT cord-025920-9p5x26ge 15 4 frequency frequency NN cord-025920-9p5x26ge 15 5 of of IN cord-025920-9p5x26ge 15 6 adjunctive adjunctive JJ cord-025920-9p5x26ge 15 7 therapy therapy NN cord-025920-9p5x26ge 15 8 use use NN cord-025920-9p5x26ge 15 9 all all DT cord-025920-9p5x26ge 15 10 patients patient NNS cord-025920-9p5x26ge 15 11 with with IN cord-025920-9p5x26ge 15 12 ARDS ARDS NNP cord-025920-9p5x26ge 15 13 , , , cord-025920-9p5x26ge 15 14 3 3 CD cord-025920-9p5x26ge 15 15 a a DT cord-025920-9p5x26ge 15 16 closer close JJR cord-025920-9p5x26ge 15 17 look look NN cord-025920-9p5x26ge 15 18 at at IN cord-025920-9p5x26ge 15 19 patients patient NNS cord-025920-9p5x26ge 15 20 with with IN cord-025920-9p5x26ge 15 21 a a DT cord-025920-9p5x26ge 15 22 PaO pao JJ cord-025920-9p5x26ge 15 23 2 2 CD cord-025920-9p5x26ge 15 24 /FIO /fio SYM cord-025920-9p5x26ge 15 25 2 2 CD cord-025920-9p5x26ge 15 26 ratio ratio NN cord-025920-9p5x26ge 15 27 < < XX cord-025920-9p5x26ge 15 28 150 150 CD cord-025920-9p5x26ge 15 29 is be VBZ cord-025920-9p5x26ge 15 30 needed need VBN cord-025920-9p5x26ge 15 31 , , , cord-025920-9p5x26ge 15 32 as as IN cord-025920-9p5x26ge 15 33 it -PRON- PRP cord-025920-9p5x26ge 15 34 is be VBZ cord-025920-9p5x26ge 15 35 primarily primarily RB cord-025920-9p5x26ge 15 36 this this DT cord-025920-9p5x26ge 15 37 subset subset NN cord-025920-9p5x26ge 15 38 of of IN cord-025920-9p5x26ge 15 39 patients patient NNS cord-025920-9p5x26ge 15 40 in in IN cord-025920-9p5x26ge 15 41 whom whom WP cord-025920-9p5x26ge 15 42 adjunctive adjunctive JJ cord-025920-9p5x26ge 15 43 therapies therapy NNS cord-025920-9p5x26ge 15 44 are be VBP cord-025920-9p5x26ge 15 45 recommended recommend VBN cord-025920-9p5x26ge 15 46 . . . cord-025920-9p5x26ge 16 1 In in IN cord-025920-9p5x26ge 16 2 this this DT cord-025920-9p5x26ge 16 3 cohort cohort NN cord-025920-9p5x26ge 16 4 assembled assemble VBD cord-025920-9p5x26ge 16 5 in in IN cord-025920-9p5x26ge 16 6 2014 2014 CD cord-025920-9p5x26ge 16 7 , , , cord-025920-9p5x26ge 16 8 a a DT cord-025920-9p5x26ge 16 9 small small JJ cord-025920-9p5x26ge 16 10 proportion proportion NN cord-025920-9p5x26ge 16 11 of of IN cord-025920-9p5x26ge 16 12 patients patient NNS cord-025920-9p5x26ge 16 13 with with IN cord-025920-9p5x26ge 16 14 moderate moderate JJ cord-025920-9p5x26ge 16 15 to to IN cord-025920-9p5x26ge 16 16 severe severe JJ cord-025920-9p5x26ge 16 17 ARDS ARDS NNP cord-025920-9p5x26ge 16 18 ( ( -LRB- cord-025920-9p5x26ge 16 19 29 29 CD cord-025920-9p5x26ge 16 20 % % NN cord-025920-9p5x26ge 16 21 ) ) -RRB- cord-025920-9p5x26ge 16 22 received receive VBD cord-025920-9p5x26ge 16 23 early early JJ cord-025920-9p5x26ge 16 24 adjunctive adjunctive JJ cord-025920-9p5x26ge 16 25 therapy therapy NN cord-025920-9p5x26ge 16 26 ; ; : cord-025920-9p5x26ge 16 27 the the DT cord-025920-9p5x26ge 16 28 most most RBS cord-025920-9p5x26ge 16 29 frequently frequently RB cord-025920-9p5x26ge 16 30 used use VBN cord-025920-9p5x26ge 16 31 modality modality NN cord-025920-9p5x26ge 16 32 was be VBD cord-025920-9p5x26ge 16 33 neuromuscular neuromuscular JJ cord-025920-9p5x26ge 16 34 blockade blockade NN cord-025920-9p5x26ge 16 35 ( ( -LRB- cord-025920-9p5x26ge 16 36 22 22 CD cord-025920-9p5x26ge 16 37 % % NN cord-025920-9p5x26ge 16 38 ) ) -RRB- cord-025920-9p5x26ge 16 39 . . . cord-025920-9p5x26ge 17 1 Prone prone JJ cord-025920-9p5x26ge 17 2 positioning positioning NN cord-025920-9p5x26ge 17 3 , , , cord-025920-9p5x26ge 17 4 the the DT cord-025920-9p5x26ge 17 5 adjunctive adjunctive JJ cord-025920-9p5x26ge 17 6 therapy therapy NN cord-025920-9p5x26ge 17 7 that that WDT cord-025920-9p5x26ge 17 8 has have VBZ cord-025920-9p5x26ge 17 9 most most RBS cord-025920-9p5x26ge 17 10 clearly clearly RB cord-025920-9p5x26ge 17 11 been be VBN cord-025920-9p5x26ge 17 12 shown show VBN cord-025920-9p5x26ge 17 13 to to TO cord-025920-9p5x26ge 17 14 have have VB cord-025920-9p5x26ge 17 15 a a DT cord-025920-9p5x26ge 17 16 survival survival NN cord-025920-9p5x26ge 17 17 benefit benefit NN cord-025920-9p5x26ge 17 18 in in IN cord-025920-9p5x26ge 17 19 ARDS ARDS NNP cord-025920-9p5x26ge 17 20 , , , cord-025920-9p5x26ge 17 21 4 4 CD cord-025920-9p5x26ge 17 22 was be VBD cord-025920-9p5x26ge 17 23 only only RB cord-025920-9p5x26ge 17 24 used use VBN cord-025920-9p5x26ge 17 25 in in IN cord-025920-9p5x26ge 17 26 11 11 CD cord-025920-9p5x26ge 17 27 % % NN cord-025920-9p5x26ge 17 28 of of IN cord-025920-9p5x26ge 17 29 patients patient NNS cord-025920-9p5x26ge 17 30 . . . cord-025920-9p5x26ge 18 1 This this DT cord-025920-9p5x26ge 18 2 study study NN cord-025920-9p5x26ge 18 3 2 2 CD cord-025920-9p5x26ge 18 4 sheds shed VBZ cord-025920-9p5x26ge 18 5 some some DT cord-025920-9p5x26ge 18 6 light light NN cord-025920-9p5x26ge 18 7 on on IN cord-025920-9p5x26ge 18 8 the the DT cord-025920-9p5x26ge 18 9 patient- patient- NN cord-025920-9p5x26ge 18 10 , , , cord-025920-9p5x26ge 18 11 clinician- clinician- NN cord-025920-9p5x26ge 18 12 , , , cord-025920-9p5x26ge 18 13 and and CC cord-025920-9p5x26ge 18 14 systems system NNS cord-025920-9p5x26ge 18 15 - - HYPH cord-025920-9p5x26ge 18 16 level level NN cord-025920-9p5x26ge 18 17 factors factor NNS cord-025920-9p5x26ge 18 18 associated associate VBN cord-025920-9p5x26ge 18 19 with with IN cord-025920-9p5x26ge 18 20 the the DT cord-025920-9p5x26ge 18 21 use use NN cord-025920-9p5x26ge 18 22 of of IN cord-025920-9p5x26ge 18 23 adjunctive adjunctive JJ cord-025920-9p5x26ge 18 24 therapy therapy NN cord-025920-9p5x26ge 18 25 , , , cord-025920-9p5x26ge 18 26 but but CC cord-025920-9p5x26ge 18 27 many many JJ cord-025920-9p5x26ge 18 28 questions question NNS cord-025920-9p5x26ge 18 29 remain remain VBP cord-025920-9p5x26ge 18 30 . . . cord-025920-9p5x26ge 19 1 Although although IN cord-025920-9p5x26ge 19 2 the the DT cord-025920-9p5x26ge 19 3 patient patient NN cord-025920-9p5x26ge 19 4 - - HYPH cord-025920-9p5x26ge 19 5 level level NN cord-025920-9p5x26ge 19 6 characteristics characteristic NNS cord-025920-9p5x26ge 19 7 associated associate VBN cord-025920-9p5x26ge 19 8 with with IN cord-025920-9p5x26ge 19 9 adjunctive adjunctive JJ cord-025920-9p5x26ge 19 10 therapy therapy NN cord-025920-9p5x26ge 19 11 use use NN cord-025920-9p5x26ge 19 12 ( ( -LRB- cord-025920-9p5x26ge 19 13 younger young JJR cord-025920-9p5x26ge 19 14 age age NN cord-025920-9p5x26ge 19 15 , , , cord-025920-9p5x26ge 19 16 more more RBR cord-025920-9p5x26ge 19 17 severe severe JJ cord-025920-9p5x26ge 19 18 hypoxia hypoxia NN cord-025920-9p5x26ge 19 19 , , , cord-025920-9p5x26ge 19 20 and and CC cord-025920-9p5x26ge 19 21 hypercapnia hypercapnia NN cord-025920-9p5x26ge 19 22 ) ) -RRB- cord-025920-9p5x26ge 19 23 are be VBP cord-025920-9p5x26ge 19 24 unsurprising unsurprising JJ cord-025920-9p5x26ge 19 25 , , , cord-025920-9p5x26ge 19 26 other other JJ cord-025920-9p5x26ge 19 27 elements element NNS cord-025920-9p5x26ge 19 28 associated associate VBN cord-025920-9p5x26ge 19 29 with with IN cord-025920-9p5x26ge 19 30 adjunctive adjunctive JJ cord-025920-9p5x26ge 19 31 therapy therapy NN cord-025920-9p5x26ge 19 32 use use NN cord-025920-9p5x26ge 19 33 are be VBP cord-025920-9p5x26ge 19 34 thought think VBN cord-025920-9p5x26ge 19 35 - - HYPH cord-025920-9p5x26ge 19 36 provoking provoke VBG cord-025920-9p5x26ge 19 37 and and CC cord-025920-9p5x26ge 19 38 warrant warrant VB cord-025920-9p5x26ge 19 39 more more JJR cord-025920-9p5x26ge 19 40 in in IN cord-025920-9p5x26ge 19 41 - - HYPH cord-025920-9p5x26ge 19 42 depth depth NN cord-025920-9p5x26ge 19 43 investigation investigation NN cord-025920-9p5x26ge 19 44 . . . cord-025920-9p5x26ge 20 1 The the DT cord-025920-9p5x26ge 20 2 finding finding NN cord-025920-9p5x26ge 20 3 that that IN cord-025920-9p5x26ge 20 4 differences difference NNS cord-025920-9p5x26ge 20 5 in in IN cord-025920-9p5x26ge 20 6 geoeconomic geoeconomic NNP cord-025920-9p5x26ge 20 7 region region NN cord-025920-9p5x26ge 20 8 and and CC cord-025920-9p5x26ge 20 9 clinician clinician NN cord-025920-9p5x26ge 20 10 staffing staffing NN cord-025920-9p5x26ge 20 11 ratios ratio NNS cord-025920-9p5x26ge 20 12 were be VBD cord-025920-9p5x26ge 20 13 associated associate VBN cord-025920-9p5x26ge 20 14 with with IN cord-025920-9p5x26ge 20 15 different different JJ cord-025920-9p5x26ge 20 16 rates rate NNS cord-025920-9p5x26ge 20 17 of of IN cord-025920-9p5x26ge 20 18 adjunctive adjunctive JJ cord-025920-9p5x26ge 20 19 therapy therapy NN cord-025920-9p5x26ge 20 20 use use NN cord-025920-9p5x26ge 20 21 suggests suggest VBZ cord-025920-9p5x26ge 20 22 that that IN cord-025920-9p5x26ge 20 23 health health NN cord-025920-9p5x26ge 20 24 systems system NNS cord-025920-9p5x26ge 20 25 - - HYPH cord-025920-9p5x26ge 20 26 level level NN cord-025920-9p5x26ge 20 27 issues issue NNS cord-025920-9p5x26ge 20 28 play play VBP cord-025920-9p5x26ge 20 29 a a DT cord-025920-9p5x26ge 20 30 role role NN cord-025920-9p5x26ge 20 31 . . . cord-025920-9p5x26ge 21 1 Among among IN cord-025920-9p5x26ge 21 2 high high JJ cord-025920-9p5x26ge 21 3 - - HYPH cord-025920-9p5x26ge 21 4 income income NN cord-025920-9p5x26ge 21 5 countries country NNS cord-025920-9p5x26ge 21 6 , , , cord-025920-9p5x26ge 21 7 the the DT cord-025920-9p5x26ge 21 8 fact fact NN cord-025920-9p5x26ge 21 9 that that IN cord-025920-9p5x26ge 21 10 decreased decrease VBD cord-025920-9p5x26ge 21 11 adjunctive adjunctive JJ cord-025920-9p5x26ge 21 12 therapy therapy NN cord-025920-9p5x26ge 21 13 use use NN cord-025920-9p5x26ge 21 14 was be VBD cord-025920-9p5x26ge 21 15 seen see VBN cord-025920-9p5x26ge 21 16 in in IN cord-025920-9p5x26ge 21 17 non non JJ cord-025920-9p5x26ge 21 18 - - JJ cord-025920-9p5x26ge 21 19 European european JJ cord-025920-9p5x26ge 21 20 countries country NNS cord-025920-9p5x26ge 21 21 compared compare VBN cord-025920-9p5x26ge 21 22 with with IN cord-025920-9p5x26ge 21 23 European european JJ cord-025920-9p5x26ge 21 24 countries country NNS cord-025920-9p5x26ge 21 25 was be VBD cord-025920-9p5x26ge 21 26 particularly particularly RB cord-025920-9p5x26ge 21 27 compelling compelling JJ cord-025920-9p5x26ge 21 28 , , , cord-025920-9p5x26ge 21 29 as as IN cord-025920-9p5x26ge 21 30 this this DT cord-025920-9p5x26ge 21 31 finding finding NN cord-025920-9p5x26ge 21 32 suggests suggest VBZ cord-025920-9p5x26ge 21 33 that that IN cord-025920-9p5x26ge 21 34 the the DT cord-025920-9p5x26ge 21 35 disparities disparity NNS cord-025920-9p5x26ge 21 36 were be VBD cord-025920-9p5x26ge 21 37 not not RB cord-025920-9p5x26ge 21 38 solely solely RB cord-025920-9p5x26ge 21 39 related relate VBN cord-025920-9p5x26ge 21 40 to to IN cord-025920-9p5x26ge 21 41 cost cost NN cord-025920-9p5x26ge 21 42 . . . cord-025920-9p5x26ge 22 1 These these DT cord-025920-9p5x26ge 22 2 relationships relationship NNS cord-025920-9p5x26ge 22 3 must must MD cord-025920-9p5x26ge 22 4 be be VB cord-025920-9p5x26ge 22 5 examined examine VBN cord-025920-9p5x26ge 22 6 further further RB cord-025920-9p5x26ge 22 7 . . . cord-025920-9p5x26ge 23 1 Regarding regard VBG cord-025920-9p5x26ge 23 2 clinician clinician JJ cord-025920-9p5x26ge 23 3 - - HYPH cord-025920-9p5x26ge 23 4 level level NN cord-025920-9p5x26ge 23 5 factors factor NNS cord-025920-9p5x26ge 23 6 , , , cord-025920-9p5x26ge 23 7 it -PRON- PRP cord-025920-9p5x26ge 23 8 is be VBZ cord-025920-9p5x26ge 23 9 worth worth JJ cord-025920-9p5x26ge 23 10 highlighting highlight VBG cord-025920-9p5x26ge 23 11 that that DT cord-025920-9p5x26ge 23 12 adjunctive adjunctive JJ cord-025920-9p5x26ge 23 13 therapy therapy NN cord-025920-9p5x26ge 23 14 was be VBD cord-025920-9p5x26ge 23 15 used use VBN cord-025920-9p5x26ge 23 16 more more RBR cord-025920-9p5x26ge 23 17 frequently frequently RB cord-025920-9p5x26ge 23 18 in in IN cord-025920-9p5x26ge 23 19 patients patient NNS cord-025920-9p5x26ge 23 20 who who WP cord-025920-9p5x26ge 23 21 had have VBD cord-025920-9p5x26ge 23 22 ARDS ARDS NNP cord-025920-9p5x26ge 23 23 recognized recognize VBN cord-025920-9p5x26ge 23 24 on on IN cord-025920-9p5x26ge 23 25 day day NN cord-025920-9p5x26ge 23 26 1 1 CD cord-025920-9p5x26ge 23 27 . . . cord-025920-9p5x26ge 24 1 2 2 LS cord-025920-9p5x26ge 25 1 The the DT cord-025920-9p5x26ge 25 2 underrecognition underrecognition NN cord-025920-9p5x26ge 25 3 of of IN cord-025920-9p5x26ge 25 4 ARDS ARDS NNP cord-025920-9p5x26ge 25 5 by by IN cord-025920-9p5x26ge 25 6 clinicians clinician NNS cord-025920-9p5x26ge 25 7 has have VBZ cord-025920-9p5x26ge 25 8 been be VBN cord-025920-9p5x26ge 25 9 previously previously RB cord-025920-9p5x26ge 25 10 reported report VBN cord-025920-9p5x26ge 25 11 , , , cord-025920-9p5x26ge 25 12 3 3 CD cord-025920-9p5x26ge 25 13 and and CC cord-025920-9p5x26ge 25 14 this this DT cord-025920-9p5x26ge 25 15 phenomenon phenomenon NN cord-025920-9p5x26ge 25 16 likely likely RB cord-025920-9p5x26ge 25 17 affects affect VBZ cord-025920-9p5x26ge 25 18 treatment treatment NN cord-025920-9p5x26ge 25 19 decisions decision NNS cord-025920-9p5x26ge 25 20 . . . cord-025920-9p5x26ge 26 1 Additional additional JJ cord-025920-9p5x26ge 26 2 clinician clinician JJ cord-025920-9p5x26ge 26 3 - - HYPH cord-025920-9p5x26ge 26 4 level level NN cord-025920-9p5x26ge 26 5 factors factor NNS cord-025920-9p5x26ge 26 6 that that WDT cord-025920-9p5x26ge 26 7 might may MD cord-025920-9p5x26ge 26 8 play play VB cord-025920-9p5x26ge 26 9 a a DT cord-025920-9p5x26ge 26 10 role role NN cord-025920-9p5x26ge 26 11 in in IN cord-025920-9p5x26ge 26 12 adjunctive adjunctive JJ cord-025920-9p5x26ge 26 13 therapy therapy NN cord-025920-9p5x26ge 26 14 use use NN cord-025920-9p5x26ge 26 15 were be VBD cord-025920-9p5x26ge 26 16 not not RB cord-025920-9p5x26ge 26 17 addressed address VBN cord-025920-9p5x26ge 26 18 in in IN cord-025920-9p5x26ge 26 19 the the DT cord-025920-9p5x26ge 26 20 current current JJ cord-025920-9p5x26ge 26 21 study study NN cord-025920-9p5x26ge 26 22 but but CC cord-025920-9p5x26ge 26 23 may may MD cord-025920-9p5x26ge 26 24 include include VB cord-025920-9p5x26ge 26 25 expertise expertise NN cord-025920-9p5x26ge 26 26 with with IN cord-025920-9p5x26ge 26 27 specific specific JJ cord-025920-9p5x26ge 26 28 modalities modality NNS cord-025920-9p5x26ge 26 29 , , , cord-025920-9p5x26ge 26 30 5 5 CD cord-025920-9p5x26ge 26 31 or or CC cord-025920-9p5x26ge 26 32 lack lack NN cord-025920-9p5x26ge 26 33 of of IN cord-025920-9p5x26ge 26 34 belief belief NN cord-025920-9p5x26ge 26 35 in in IN cord-025920-9p5x26ge 26 36 their -PRON- PRP$ cord-025920-9p5x26ge 26 37 utility utility NN cord-025920-9p5x26ge 26 38 . . . cord-025920-9p5x26ge 27 1 Benefits benefit NNS cord-025920-9p5x26ge 27 2 of of IN cord-025920-9p5x26ge 27 3 adjunctive adjunctive JJ cord-025920-9p5x26ge 27 4 therapies therapy NNS cord-025920-9p5x26ge 27 5 are be VBP cord-025920-9p5x26ge 27 6 less less RBR cord-025920-9p5x26ge 27 7 well well RB cord-025920-9p5x26ge 27 8 established establish VBN cord-025920-9p5x26ge 27 9 than than IN cord-025920-9p5x26ge 27 10 benefits benefit NNS cord-025920-9p5x26ge 27 11 of of IN cord-025920-9p5x26ge 27 12 low low JJ cord-025920-9p5x26ge 27 13 tidal tidal JJ cord-025920-9p5x26ge 27 14 volume volume NN cord-025920-9p5x26ge 27 15 ventilation ventilation NN cord-025920-9p5x26ge 27 16 . . . cord-025920-9p5x26ge 28 1 Randomized randomized JJ cord-025920-9p5x26ge 28 2 controlled control VBN cord-025920-9p5x26ge 28 3 trials trial NNS cord-025920-9p5x26ge 28 4 , , , cord-025920-9p5x26ge 28 5 including include VBG cord-025920-9p5x26ge 28 6 the the DT cord-025920-9p5x26ge 28 7 Reevaluation Reevaluation NNP cord-025920-9p5x26ge 28 8 Of of IN cord-025920-9p5x26ge 28 9 Systemic Systemic NNP cord-025920-9p5x26ge 28 10 Early early JJ cord-025920-9p5x26ge 28 11 Neuromuscular Neuromuscular NNP cord-025920-9p5x26ge 28 12 Blockade Blockade NNP cord-025920-9p5x26ge 28 13 ( ( -LRB- cord-025920-9p5x26ge 28 14 ROSE rose NN cord-025920-9p5x26ge 28 15 ) ) -RRB- cord-025920-9p5x26ge 28 16 6 6 CD cord-025920-9p5x26ge 28 17 and and CC cord-025920-9p5x26ge 28 18 Extracorporeal extracorporeal JJ cord-025920-9p5x26ge 28 19 Membrane membrane NN cord-025920-9p5x26ge 28 20 Oxygenation oxygenation NN cord-025920-9p5x26ge 28 21 for for IN cord-025920-9p5x26ge 28 22 Severe severe JJ cord-025920-9p5x26ge 28 23 Acute acute JJ cord-025920-9p5x26ge 28 24 Respiratory respiratory JJ cord-025920-9p5x26ge 28 25 Distress Distress NNP cord-025920-9p5x26ge 28 26 Syndrome Syndrome NNP cord-025920-9p5x26ge 28 27 ( ( -LRB- cord-025920-9p5x26ge 28 28 EOLIA EOLIA NNP cord-025920-9p5x26ge 28 29 ) ) -RRB- cord-025920-9p5x26ge 28 30 , , , cord-025920-9p5x26ge 28 31 7 7 CD cord-025920-9p5x26ge 28 32 chestjournal.org chestjournal.org NN cord-025920-9p5x26ge 28 33 blockade blockade NN cord-025920-9p5x26ge 28 34 or or CC cord-025920-9p5x26ge 28 35 extracorporeal extracorporeal JJ cord-025920-9p5x26ge 28 36 membrane membrane NN cord-025920-9p5x26ge 28 37 oxygenation oxygenation NN cord-025920-9p5x26ge 28 38 in in IN cord-025920-9p5x26ge 28 39 patients patient NNS cord-025920-9p5x26ge 28 40 with with IN cord-025920-9p5x26ge 28 41 ARDS ARDS NNP cord-025920-9p5x26ge 28 42 with with IN cord-025920-9p5x26ge 28 43 specific specific JJ cord-025920-9p5x26ge 28 44 levels level NNS cord-025920-9p5x26ge 28 45 of of IN cord-025920-9p5x26ge 28 46 hypoxia hypoxia NN cord-025920-9p5x26ge 28 47 . . . cord-025920-9p5x26ge 29 1 Previous previous JJ cord-025920-9p5x26ge 29 2 studies study NNS cord-025920-9p5x26ge 29 3 have have VBP cord-025920-9p5x26ge 29 4 suggested suggest VBN cord-025920-9p5x26ge 29 5 possible possible JJ cord-025920-9p5x26ge 29 6 harm harm NN cord-025920-9p5x26ge 29 7 associated associate VBN cord-025920-9p5x26ge 29 8 with with IN cord-025920-9p5x26ge 29 9 the the DT cord-025920-9p5x26ge 29 10 use use NN cord-025920-9p5x26ge 29 11 of of IN cord-025920-9p5x26ge 29 12 pulmonary pulmonary JJ cord-025920-9p5x26ge 29 13 vasodilators vasodilator NNS cord-025920-9p5x26ge 29 14 . . . cord-025920-9p5x26ge 30 1 8 8 CD cord-025920-9p5x26ge 30 2 , , , cord-025920-9p5x26ge 30 3 9 9 CD cord-025920-9p5x26ge 31 1 Thus thus RB cord-025920-9p5x26ge 31 2 , , , cord-025920-9p5x26ge 31 3 clinician clinician NN cord-025920-9p5x26ge 31 4 reservation reservation NN cord-025920-9p5x26ge 31 5 for for IN cord-025920-9p5x26ge 31 6 the the DT cord-025920-9p5x26ge 31 7 utilization utilization NN cord-025920-9p5x26ge 31 8 of of IN cord-025920-9p5x26ge 31 9 these these DT cord-025920-9p5x26ge 31 10 therapies therapy NNS cord-025920-9p5x26ge 31 11 may may MD cord-025920-9p5x26ge 31 12 be be VB cord-025920-9p5x26ge 31 13 expected expect VBN cord-025920-9p5x26ge 31 14 . . . cord-025920-9p5x26ge 32 1 Conversely conversely RB cord-025920-9p5x26ge 32 2 , , , cord-025920-9p5x26ge 32 3 a a DT cord-025920-9p5x26ge 32 4 lack lack NN cord-025920-9p5x26ge 32 5 of of IN cord-025920-9p5x26ge 32 6 evidence evidence NN cord-025920-9p5x26ge 32 7 can can MD cord-025920-9p5x26ge 32 8 not not RB cord-025920-9p5x26ge 32 9 be be VB cord-025920-9p5x26ge 32 10 the the DT cord-025920-9p5x26ge 32 11 sole sole JJ cord-025920-9p5x26ge 32 12 reason reason NN cord-025920-9p5x26ge 32 13 for for IN cord-025920-9p5x26ge 32 14 the the DT cord-025920-9p5x26ge 32 15 underutilization underutilization NN cord-025920-9p5x26ge 32 16 of of IN cord-025920-9p5x26ge 32 17 adjunctive adjunctive JJ cord-025920-9p5x26ge 32 18 therapy therapy NN cord-025920-9p5x26ge 32 19 . . . cord-025920-9p5x26ge 33 1 The the DT cord-025920-9p5x26ge 33 2 ROSE ROSE NNP cord-025920-9p5x26ge 33 3 study study NN cord-025920-9p5x26ge 33 4 was be VBD cord-025920-9p5x26ge 33 5 published publish VBN cord-025920-9p5x26ge 33 6 after after IN cord-025920-9p5x26ge 33 7 the the DT cord-025920-9p5x26ge 33 8 LUNG LUNG NNP cord-025920-9p5x26ge 33 9 - - HYPH cord-025920-9p5x26ge 33 10 SAFE safe JJ cord-025920-9p5x26ge 33 11 cohort cohort NN cord-025920-9p5x26ge 33 12 was be VBD cord-025920-9p5x26ge 33 13 collected collect VBN cord-025920-9p5x26ge 33 14 . . . cord-025920-9p5x26ge 34 1 Prior prior RB cord-025920-9p5x26ge 34 2 to to IN cord-025920-9p5x26ge 34 3 ROSE ROSE NNP cord-025920-9p5x26ge 34 4 , , , cord-025920-9p5x26ge 34 5 Papazian Papazian NNP cord-025920-9p5x26ge 34 6 et et NNP cord-025920-9p5x26ge 34 7 al al NNP cord-025920-9p5x26ge 34 8 10 10 CD cord-025920-9p5x26ge 34 9 reported report VBD cord-025920-9p5x26ge 34 10 a a DT cord-025920-9p5x26ge 34 11 potential potential JJ cord-025920-9p5x26ge 34 12 mortality mortality NN cord-025920-9p5x26ge 34 13 benefit benefit NN cord-025920-9p5x26ge 34 14 associated associate VBN cord-025920-9p5x26ge 34 15 with with IN cord-025920-9p5x26ge 34 16 use use NN cord-025920-9p5x26ge 34 17 of of IN cord-025920-9p5x26ge 34 18 neuromuscular neuromuscular JJ cord-025920-9p5x26ge 34 19 blockade blockade NN cord-025920-9p5x26ge 34 20 . . . cord-025920-9p5x26ge 35 1 Although although IN cord-025920-9p5x26ge 35 2 neuromuscular neuromuscular JJ cord-025920-9p5x26ge 35 3 blockade blockade NN cord-025920-9p5x26ge 35 4 was be VBD cord-025920-9p5x26ge 35 5 the the DT cord-025920-9p5x26ge 35 6 most most RBS cord-025920-9p5x26ge 35 7 commonly commonly RB cord-025920-9p5x26ge 35 8 used use VBN cord-025920-9p5x26ge 35 9 therapy therapy NN cord-025920-9p5x26ge 35 10 in in IN cord-025920-9p5x26ge 35 11 the the DT cord-025920-9p5x26ge 35 12 cohort cohort NN cord-025920-9p5x26ge 35 13 of of IN cord-025920-9p5x26ge 35 14 Duggal Duggal NNP cord-025920-9p5x26ge 35 15 et et FW cord-025920-9p5x26ge 35 16 al al NNP cord-025920-9p5x26ge 35 17 , , , cord-025920-9p5x26ge 35 18 2 2 CD cord-025920-9p5x26ge 35 19 it -PRON- PRP cord-025920-9p5x26ge 35 20 was be VBD cord-025920-9p5x26ge 35 21 still still RB cord-025920-9p5x26ge 35 22 used use VBN cord-025920-9p5x26ge 35 23 in in IN cord-025920-9p5x26ge 35 24 less less JJR cord-025920-9p5x26ge 35 25 than than IN cord-025920-9p5x26ge 35 26 onequarter onequarter NN cord-025920-9p5x26ge 35 27 of of IN cord-025920-9p5x26ge 35 28 patients patient NNS cord-025920-9p5x26ge 35 29 with with IN cord-025920-9p5x26ge 35 30 moderate moderate JJ cord-025920-9p5x26ge 35 31 to to IN cord-025920-9p5x26ge 35 32 severe severe JJ cord-025920-9p5x26ge 35 33 ARDS ARDS NNP cord-025920-9p5x26ge 35 34 . . . cord-025920-9p5x26ge 36 1 Furthermore furthermore RB cord-025920-9p5x26ge 36 2 , , , cord-025920-9p5x26ge 36 3 there there EX cord-025920-9p5x26ge 36 4 was be VBD cord-025920-9p5x26ge 36 5 a a DT cord-025920-9p5x26ge 36 6 particularly particularly RB cord-025920-9p5x26ge 36 7 low low JJ cord-025920-9p5x26ge 36 8 rate rate NN cord-025920-9p5x26ge 36 9 of of IN cord-025920-9p5x26ge 36 10 prone prone JJ cord-025920-9p5x26ge 36 11 positioning positioning NN cord-025920-9p5x26ge 36 12 , , , cord-025920-9p5x26ge 36 13 a a DT cord-025920-9p5x26ge 36 14 modality modality NN cord-025920-9p5x26ge 36 15 that that WDT cord-025920-9p5x26ge 36 16 has have VBZ cord-025920-9p5x26ge 36 17 shown show VBN cord-025920-9p5x26ge 36 18 mortality mortality NN cord-025920-9p5x26ge 36 19 benefit benefit NN cord-025920-9p5x26ge 36 20 in in IN cord-025920-9p5x26ge 36 21 patients patient NNS cord-025920-9p5x26ge 36 22 with with IN cord-025920-9p5x26ge 36 23 moderate moderate JJ cord-025920-9p5x26ge 36 24 to to IN cord-025920-9p5x26ge 36 25 severe severe JJ cord-025920-9p5x26ge 36 26 ARDS ARDS NNP cord-025920-9p5x26ge 36 27 , , , cord-025920-9p5x26ge 36 28 yet yet CC cord-025920-9p5x26ge 36 29 remains remain VBZ cord-025920-9p5x26ge 36 30 grossly grossly RB cord-025920-9p5x26ge 36 31 underutilized underutilize VBN cord-025920-9p5x26ge 36 32 for for IN cord-025920-9p5x26ge 36 33 reasons reason NNS cord-025920-9p5x26ge 36 34 that that WDT cord-025920-9p5x26ge 36 35 are be VBP cord-025920-9p5x26ge 36 36 unclear unclear JJ cord-025920-9p5x26ge 36 37 . . . cord-025920-9p5x26ge 37 1 A a DT cord-025920-9p5x26ge 37 2 multicenter multicenter JJ cord-025920-9p5x26ge 37 3 observational observational JJ cord-025920-9p5x26ge 37 4 study study NN cord-025920-9p5x26ge 37 5 on on IN cord-025920-9p5x26ge 37 6 prone prone JJ cord-025920-9p5x26ge 37 7 positioning positioning NN cord-025920-9p5x26ge 37 8 found find VBD cord-025920-9p5x26ge 37 9 that that IN cord-025920-9p5x26ge 37 10 clinician clinician JJ cord-025920-9p5x26ge 37 11 judgment judgment NN cord-025920-9p5x26ge 37 12 of of IN cord-025920-9p5x26ge 37 13 hypoxemia hypoxemia NN cord-025920-9p5x26ge 37 14 being be VBG cord-025920-9p5x26ge 37 15 insufficiently insufficiently RB cord-025920-9p5x26ge 37 16 severe severe JJ cord-025920-9p5x26ge 37 17 was be VBD cord-025920-9p5x26ge 37 18 the the DT cord-025920-9p5x26ge 37 19 most most RBS cord-025920-9p5x26ge 37 20 common common JJ cord-025920-9p5x26ge 37 21 reason reason NN cord-025920-9p5x26ge 37 22 for for IN cord-025920-9p5x26ge 37 23 not not RB cord-025920-9p5x26ge 37 24 using use VBG cord-025920-9p5x26ge 37 25 this this DT cord-025920-9p5x26ge 37 26 therapy therapy NN cord-025920-9p5x26ge 37 27 . . . cord-025920-9p5x26ge 38 1 11 11 CD cord-025920-9p5x26ge 39 1 Although although IN cord-025920-9p5x26ge 39 2 this this DT cord-025920-9p5x26ge 39 3 indicates indicate VBZ cord-025920-9p5x26ge 39 4 a a DT cord-025920-9p5x26ge 39 5 clinician clinician JJ cord-025920-9p5x26ge 39 6 - - HYPH cord-025920-9p5x26ge 39 7 level level NN cord-025920-9p5x26ge 39 8 factor factor NN cord-025920-9p5x26ge 39 9 in in IN cord-025920-9p5x26ge 39 10 its -PRON- PRP$ cord-025920-9p5x26ge 39 11 underutilization underutilization NN cord-025920-9p5x26ge 39 12 , , , cord-025920-9p5x26ge 39 13 this this DT cord-025920-9p5x26ge 39 14 study study NN cord-025920-9p5x26ge 39 15 was be VBD cord-025920-9p5x26ge 39 16 performed perform VBN cord-025920-9p5x26ge 39 17 in in IN cord-025920-9p5x26ge 39 18 ICUs ICUs NNP cord-025920-9p5x26ge 39 19 that that WDT cord-025920-9p5x26ge 39 20 agreed agree VBD cord-025920-9p5x26ge 39 21 to to TO cord-025920-9p5x26ge 39 22 participate participate VB cord-025920-9p5x26ge 39 23 in in IN cord-025920-9p5x26ge 39 24 a a DT cord-025920-9p5x26ge 39 25 study study NN cord-025920-9p5x26ge 39 26 about about IN cord-025920-9p5x26ge 39 27 proning prone VBG cord-025920-9p5x26ge 39 28 , , , cord-025920-9p5x26ge 39 29 which which WDT cord-025920-9p5x26ge 39 30 likely likely RB cord-025920-9p5x26ge 39 31 resulted result VBD cord-025920-9p5x26ge 39 32 in in IN cord-025920-9p5x26ge 39 33 a a DT cord-025920-9p5x26ge 39 34 selection selection NN cord-025920-9p5x26ge 39 35 bias bias NN cord-025920-9p5x26ge 39 36 toward toward IN cord-025920-9p5x26ge 39 37 centers center NNS cord-025920-9p5x26ge 39 38 whose whose WP$ cord-025920-9p5x26ge 39 39 staff staff NN cord-025920-9p5x26ge 39 40 were be VBD cord-025920-9p5x26ge 39 41 trained train VBN cord-025920-9p5x26ge 39 42 in in IN cord-025920-9p5x26ge 39 43 this this DT cord-025920-9p5x26ge 39 44 technique technique NN cord-025920-9p5x26ge 39 45 . . . cord-025920-9p5x26ge 40 1 The the DT cord-025920-9p5x26ge 40 2 level level NN cord-025920-9p5x26ge 40 3 of of IN cord-025920-9p5x26ge 40 4 clinician clinician NN cord-025920-9p5x26ge 40 5 training training NN cord-025920-9p5x26ge 40 6 and and CC cord-025920-9p5x26ge 40 7 comfort comfort NN cord-025920-9p5x26ge 40 8 with with IN cord-025920-9p5x26ge 40 9 prone prone JJ cord-025920-9p5x26ge 40 10 positioning positioning NN cord-025920-9p5x26ge 40 11 outside outside IN cord-025920-9p5x26ge 40 12 of of IN cord-025920-9p5x26ge 40 13 centers center NNS cord-025920-9p5x26ge 40 14 participating participate VBG cord-025920-9p5x26ge 40 15 in in IN cord-025920-9p5x26ge 40 16 clinical clinical JJ cord-025920-9p5x26ge 40 17 research research NN cord-025920-9p5x26ge 40 18 has have VBZ cord-025920-9p5x26ge 40 19 not not RB cord-025920-9p5x26ge 40 20 yet yet RB cord-025920-9p5x26ge 40 21 been be VBN cord-025920-9p5x26ge 40 22 established establish VBN cord-025920-9p5x26ge 40 23 and and CC cord-025920-9p5x26ge 40 24 potentially potentially RB cord-025920-9p5x26ge 40 25 plays play VBZ cord-025920-9p5x26ge 40 26 a a DT cord-025920-9p5x26ge 40 27 substantial substantial JJ cord-025920-9p5x26ge 40 28 role role NN cord-025920-9p5x26ge 40 29 in in IN cord-025920-9p5x26ge 40 30 its -PRON- PRP$ cord-025920-9p5x26ge 40 31 underuse underuse NN cord-025920-9p5x26ge 40 32 . . . cord-025920-9p5x26ge 41 1 Duggal Duggal NNP cord-025920-9p5x26ge 41 2 et et FW cord-025920-9p5x26ge 41 3 al al NNP cord-025920-9p5x26ge 41 4 2 2 CD cord-025920-9p5x26ge 41 5 categorize categorize VBP cord-025920-9p5x26ge 41 6 prone prone JJ cord-025920-9p5x26ge 41 7 positioning positioning NN cord-025920-9p5x26ge 41 8 as as IN cord-025920-9p5x26ge 41 9 a a DT cord-025920-9p5x26ge 41 10 " " `` cord-025920-9p5x26ge 41 11 widely widely RB cord-025920-9p5x26ge 41 12 available available JJ cord-025920-9p5x26ge 41 13 " " '' cord-025920-9p5x26ge 41 14 adjunctive adjunctive JJ cord-025920-9p5x26ge 41 15 therapy therapy NN cord-025920-9p5x26ge 41 16 due due IN cord-025920-9p5x26ge 41 17 to to IN cord-025920-9p5x26ge 41 18 the the DT cord-025920-9p5x26ge 41 19 lack lack NN cord-025920-9p5x26ge 41 20 of of IN cord-025920-9p5x26ge 41 21 requirement requirement NN cord-025920-9p5x26ge 41 22 for for IN cord-025920-9p5x26ge 41 23 specialized specialized JJ cord-025920-9p5x26ge 41 24 equipment equipment NN cord-025920-9p5x26ge 41 25 . . . cord-025920-9p5x26ge 42 1 Although although IN cord-025920-9p5x26ge 42 2 specific specific JJ cord-025920-9p5x26ge 42 3 technology technology NN cord-025920-9p5x26ge 42 4 is be VBZ cord-025920-9p5x26ge 42 5 not not RB cord-025920-9p5x26ge 42 6 required require VBN cord-025920-9p5x26ge 42 7 for for IN cord-025920-9p5x26ge 42 8 prone prone JJ cord-025920-9p5x26ge 42 9 positioning positioning NN cord-025920-9p5x26ge 42 10 , , , cord-025920-9p5x26ge 42 11 training training NN cord-025920-9p5x26ge 42 12 and and CC cord-025920-9p5x26ge 42 13 expertise expertise NN cord-025920-9p5x26ge 42 14 of of IN cord-025920-9p5x26ge 42 15 physicians physician NNS cord-025920-9p5x26ge 42 16 and and CC cord-025920-9p5x26ge 42 17 allied allied JJ cord-025920-9p5x26ge 42 18 health health NN cord-025920-9p5x26ge 42 19 professionals professional NNS cord-025920-9p5x26ge 42 20 are be VBP cord-025920-9p5x26ge 42 21 crucial crucial JJ cord-025920-9p5x26ge 42 22 and and CC cord-025920-9p5x26ge 42 23 may may MD cord-025920-9p5x26ge 42 24 be be VB cord-025920-9p5x26ge 42 25 lacking lack VBG cord-025920-9p5x26ge 42 26 in in IN cord-025920-9p5x26ge 42 27 some some DT cord-025920-9p5x26ge 42 28 centers center NNS cord-025920-9p5x26ge 42 29 . . . cord-025920-9p5x26ge 43 1 Prone prone JJ cord-025920-9p5x26ge 43 2 positioning positioning NN cord-025920-9p5x26ge 43 3 can can MD cord-025920-9p5x26ge 43 4 also also RB cord-025920-9p5x26ge 43 5 be be VB cord-025920-9p5x26ge 43 6 more more RBR cord-025920-9p5x26ge 43 7 laborintensive laborintensive NN cord-025920-9p5x26ge 43 8 for for IN cord-025920-9p5x26ge 43 9 nursing nursing NN cord-025920-9p5x26ge 43 10 staff staff NN cord-025920-9p5x26ge 43 11 , , , cord-025920-9p5x26ge 43 12 making make VBG cord-025920-9p5x26ge 43 13 it -PRON- PRP cord-025920-9p5x26ge 43 14 less less RBR cord-025920-9p5x26ge 43 15 feasible feasible JJ cord-025920-9p5x26ge 43 16 in in IN cord-025920-9p5x26ge 43 17 centers center NNS cord-025920-9p5x26ge 43 18 with with IN cord-025920-9p5x26ge 43 19 lower low JJR cord-025920-9p5x26ge 43 20 nurse nurse NN cord-025920-9p5x26ge 43 21 - - HYPH cord-025920-9p5x26ge 43 22 to to IN cord-025920-9p5x26ge 43 23 - - HYPH cord-025920-9p5x26ge 43 24 patient patient NN cord-025920-9p5x26ge 43 25 ratios ratio NNS cord-025920-9p5x26ge 43 26 . . . cord-025920-9p5x26ge 44 1 All all DT cord-025920-9p5x26ge 44 2 of of IN cord-025920-9p5x26ge 44 3 these these DT cord-025920-9p5x26ge 44 4 factors factor NNS cord-025920-9p5x26ge 44 5 may may MD cord-025920-9p5x26ge 44 6 prevent prevent VB cord-025920-9p5x26ge 44 7 prone prone JJ cord-025920-9p5x26ge 44 8 positioning positioning NN cord-025920-9p5x26ge 44 9 from from IN cord-025920-9p5x26ge 44 10 indeed indeed RB cord-025920-9p5x26ge 44 11 being be VBG cord-025920-9p5x26ge 44 12 a a DT cord-025920-9p5x26ge 44 13 widely widely RB cord-025920-9p5x26ge 44 14 available available JJ cord-025920-9p5x26ge 44 15 therapy therapy NN cord-025920-9p5x26ge 44 16 in in IN cord-025920-9p5x26ge 44 17 a a DT cord-025920-9p5x26ge 44 18 practical practical JJ cord-025920-9p5x26ge 44 19 sense sense NN cord-025920-9p5x26ge 44 20 . . . cord-025920-9p5x26ge 45 1 Ultimately ultimately RB cord-025920-9p5x26ge 45 2 , , , cord-025920-9p5x26ge 45 3 the the DT cord-025920-9p5x26ge 45 4 study study NN cord-025920-9p5x26ge 45 5 by by IN cord-025920-9p5x26ge 45 6 Duggal Duggal NNP cord-025920-9p5x26ge 45 7 et et NNP cord-025920-9p5x26ge 45 8 al al NNP cord-025920-9p5x26ge 45 9 2 2 CD cord-025920-9p5x26ge 45 10 highlights highlight VBZ cord-025920-9p5x26ge 45 11 the the DT cord-025920-9p5x26ge 45 12 disconnect disconnect NN cord-025920-9p5x26ge 45 13 between between IN cord-025920-9p5x26ge 45 14 evidence evidence NN cord-025920-9p5x26ge 45 15 - - HYPH cord-025920-9p5x26ge 45 16 based base VBN cord-025920-9p5x26ge 45 17 society society NN cord-025920-9p5x26ge 45 18 guidelines guideline NNS cord-025920-9p5x26ge 45 19 12 12 CD cord-025920-9p5x26ge 45 20 and and CC cord-025920-9p5x26ge 45 21 actual actual JJ cord-025920-9p5x26ge 45 22 practice practice NN cord-025920-9p5x26ge 45 23 patterns pattern NNS cord-025920-9p5x26ge 45 24 in in IN cord-025920-9p5x26ge 45 25 the the DT cord-025920-9p5x26ge 45 26 real real JJ cord-025920-9p5x26ge 45 27 world world NN cord-025920-9p5x26ge 45 28 . . . cord-025920-9p5x26ge 46 1 Whether whether IN cord-025920-9p5x26ge 46 2 this this DT cord-025920-9p5x26ge 46 3 disconnect disconnect NN cord-025920-9p5x26ge 46 4 has have VBZ cord-025920-9p5x26ge 46 5 persisted persist VBN cord-025920-9p5x26ge 46 6 in in IN cord-025920-9p5x26ge 46 7 the the DT cord-025920-9p5x26ge 46 8 setting setting NN cord-025920-9p5x26ge 46 9 of of IN cord-025920-9p5x26ge 46 10 the the DT cord-025920-9p5x26ge 46 11 COVID-19 covid-19 JJ cord-025920-9p5x26ge 46 12 pandemic pandemic NN cord-025920-9p5x26ge 46 13 has have VBZ cord-025920-9p5x26ge 46 14 yet yet RB cord-025920-9p5x26ge 46 15 to to TO cord-025920-9p5x26ge 46 16 be be VB cord-025920-9p5x26ge 46 17 seen see VBN cord-025920-9p5x26ge 46 18 . . . cord-025920-9p5x26ge 47 1 Nevertheless nevertheless RB cord-025920-9p5x26ge 47 2 , , , cord-025920-9p5x26ge 47 3 barriers barrier NNS cord-025920-9p5x26ge 47 4 to to IN cord-025920-9p5x26ge 47 5 the the DT cord-025920-9p5x26ge 47 6 use use NN cord-025920-9p5x26ge 47 7 of of IN cord-025920-9p5x26ge 47 8 adjunctive adjunctive JJ cord-025920-9p5x26ge 47 9 therapies therapy NNS cord-025920-9p5x26ge 47 10 outside outside IN cord-025920-9p5x26ge 47 11 of of IN cord-025920-9p5x26ge 47 12 the the DT cord-025920-9p5x26ge 47 13 context context NN cord-025920-9p5x26ge 47 14 of of IN cord-025920-9p5x26ge 47 15 interventional interventional JJ cord-025920-9p5x26ge 47 16 trials trial NNS cord-025920-9p5x26ge 47 17 must must MD cord-025920-9p5x26ge 47 18 be be VB cord-025920-9p5x26ge 47 19 identified identify VBN cord-025920-9p5x26ge 47 20 and and CC cord-025920-9p5x26ge 47 21 addressed address VBN cord-025920-9p5x26ge 47 22 , , , cord-025920-9p5x26ge 47 23 particularly particularly RB cord-025920-9p5x26ge 47 24 regarding regard VBG cord-025920-9p5x26ge 47 25 prone prone JJ cord-025920-9p5x26ge 47 26 positioning positioning NN cord-025920-9p5x26ge 47 27 . . . cord-025920-9p5x26ge 48 1 Although although IN cord-025920-9p5x26ge 48 2 underrecognition underrecognition NN cord-025920-9p5x26ge 48 3 of of IN cord-025920-9p5x26ge 48 4 ARDS ARDS NNP cord-025920-9p5x26ge 48 5 represents represent VBZ cord-025920-9p5x26ge 48 6 one one CD cord-025920-9p5x26ge 48 7 culprit culprit NN cord-025920-9p5x26ge 48 8 and and CC cord-025920-9p5x26ge 48 9 a a DT cord-025920-9p5x26ge 48 10 potential potential JJ cord-025920-9p5x26ge 48 11 target target NN cord-025920-9p5x26ge 48 12 for for IN cord-025920-9p5x26ge 48 13 improvement improvement NN cord-025920-9p5x26ge 48 14 , , , cord-025920-9p5x26ge 48 15 the the DT cord-025920-9p5x26ge 48 16 contribution contribution NN cord-025920-9p5x26ge 48 17 of of IN cord-025920-9p5x26ge 48 18 other other JJ cord-025920-9p5x26ge 48 19 clinician- clinician- NN cord-025920-9p5x26ge 48 20 , , , cord-025920-9p5x26ge 48 21 systems- systems- NN cord-025920-9p5x26ge 48 22 , , , cord-025920-9p5x26ge 48 23 and and CC cord-025920-9p5x26ge 48 24 patientbased patientbase VBN cord-025920-9p5x26ge 48 25 factors factor NNS cord-025920-9p5x26ge 48 26 must must MD cord-025920-9p5x26ge 48 27 be be VB cord-025920-9p5x26ge 48 28 examined examine VBN cord-025920-9p5x26ge 48 29 before before IN cord-025920-9p5x26ge 48 30 a a DT cord-025920-9p5x26ge 48 31 comprehensive comprehensive JJ cord-025920-9p5x26ge 48 32 approach approach NN cord-025920-9p5x26ge 48 33 to to IN cord-025920-9p5x26ge 48 34 implementation implementation NN cord-025920-9p5x26ge 48 35 strategies strategy NNS cord-025920-9p5x26ge 48 36 for for IN cord-025920-9p5x26ge 48 37 improving improve VBG cord-025920-9p5x26ge 48 38 ARDS ARDS NNP cord-025920-9p5x26ge 48 39 care care NN cord-025920-9p5x26ge 48 40 can can MD cord-025920-9p5x26ge 48 41 be be VB cord-025920-9p5x26ge 48 42 developed develop VBN cord-025920-9p5x26ge 48 43 . . . cord-025920-9p5x26ge 49 1 Mortality mortality NN cord-025920-9p5x26ge 49 2 in in IN cord-025920-9p5x26ge 49 3 ARDS ARDS NNP cord-025920-9p5x26ge 49 4 remains remain VBZ cord-025920-9p5x26ge 49 5 high high JJ cord-025920-9p5x26ge 49 6 ; ; : cord-025920-9p5x26ge 49 7 the the DT cord-025920-9p5x26ge 49 8 failure failure NN cord-025920-9p5x26ge 49 9 of of IN cord-025920-9p5x26ge 49 10 advances advance NNS cord-025920-9p5x26ge 49 11 in in IN cord-025920-9p5x26ge 49 12 ARDS ARDS NNP cord-025920-9p5x26ge 49 13 management management NN cord-025920-9p5x26ge 49 14 to to TO cord-025920-9p5x26ge 49 15 reach reach VB cord-025920-9p5x26ge 49 16 this this DT cord-025920-9p5x26ge 49 17 vulnerable vulnerable JJ cord-025920-9p5x26ge 49 18 patient patient JJ cord-025920-9p5x26ge 49 19 population population NN cord-025920-9p5x26ge 49 20 may may MD cord-025920-9p5x26ge 49 21 be be VB cord-025920-9p5x26ge 49 22 the the DT cord-025920-9p5x26ge 49 23 reason reason NN cord-025920-9p5x26ge 49 24 why why WRB cord-025920-9p5x26ge 49 25 . . . cord-025920-9p5x26ge 50 1 Ventilation ventilation NN cord-025920-9p5x26ge 50 2 with with IN cord-025920-9p5x26ge 50 3 lower low JJR cord-025920-9p5x26ge 50 4 tidal tidal JJ cord-025920-9p5x26ge 50 5 volumes volume NNS cord-025920-9p5x26ge 50 6 as as IN cord-025920-9p5x26ge 50 7 compared compare VBN cord-025920-9p5x26ge 50 8 with with IN cord-025920-9p5x26ge 50 9 traditional traditional JJ cord-025920-9p5x26ge 50 10 tidal tidal JJ cord-025920-9p5x26ge 50 11 volumes volume NNS cord-025920-9p5x26ge 50 12 for for IN cord-025920-9p5x26ge 50 13 acute acute JJ cord-025920-9p5x26ge 50 14 lung lung NN cord-025920-9p5x26ge 50 15 injury injury NN cord-025920-9p5x26ge 50 16 and and CC cord-025920-9p5x26ge 50 17 the the DT cord-025920-9p5x26ge 50 18 acute acute JJ cord-025920-9p5x26ge 50 19 respiratory respiratory JJ cord-025920-9p5x26ge 50 20 distress distress NN cord-025920-9p5x26ge 50 21 syndrome syndrome NN cord-025920-9p5x26ge 50 22 Patterns pattern NNS cord-025920-9p5x26ge 50 23 of of IN cord-025920-9p5x26ge 50 24 use use NN cord-025920-9p5x26ge 50 25 of of IN cord-025920-9p5x26ge 50 26 adjunctive adjunctive JJ cord-025920-9p5x26ge 50 27 therapies therapy NNS cord-025920-9p5x26ge 50 28 in in IN cord-025920-9p5x26ge 50 29 patients patient NNS cord-025920-9p5x26ge 50 30 with with IN cord-025920-9p5x26ge 50 31 early early JJ cord-025920-9p5x26ge 50 32 moderate moderate JJ cord-025920-9p5x26ge 50 33 to to IN cord-025920-9p5x26ge 50 34 severe severe JJ cord-025920-9p5x26ge 50 35 ARDS ARDS NNP cord-025920-9p5x26ge 50 36 : : : cord-025920-9p5x26ge 51 1 insights insight NNS cord-025920-9p5x26ge 51 2 from from IN cord-025920-9p5x26ge 51 3 the the DT cord-025920-9p5x26ge 51 4 LUNG LUNG NNP cord-025920-9p5x26ge 51 5 SAFE SAFE NNP cord-025920-9p5x26ge 51 6 Study Study NNP cord-025920-9p5x26ge 51 7 Epidemiology epidemiology NN cord-025920-9p5x26ge 51 8 , , , cord-025920-9p5x26ge 51 9 patterns pattern NNS cord-025920-9p5x26ge 51 10 of of IN cord-025920-9p5x26ge 51 11 care care NN cord-025920-9p5x26ge 51 12 , , , cord-025920-9p5x26ge 51 13 and and CC cord-025920-9p5x26ge 51 14 mortality mortality NN cord-025920-9p5x26ge 51 15 for for IN cord-025920-9p5x26ge 51 16 patients patient NNS cord-025920-9p5x26ge 51 17 with with IN cord-025920-9p5x26ge 51 18 acute acute JJ cord-025920-9p5x26ge 51 19 respiratory respiratory JJ cord-025920-9p5x26ge 51 20 distress distress NN cord-025920-9p5x26ge 51 21 syndrome syndrome NN cord-025920-9p5x26ge 51 22 in in IN cord-025920-9p5x26ge 51 23 intensive intensive JJ cord-025920-9p5x26ge 51 24 care care NN cord-025920-9p5x26ge 51 25 units unit NNS cord-025920-9p5x26ge 51 26 in in IN cord-025920-9p5x26ge 51 27 50 50 CD cord-025920-9p5x26ge 51 28 countries country NNS cord-025920-9p5x26ge 52 1 Prone prone JJ cord-025920-9p5x26ge 52 2 positioning positioning NN cord-025920-9p5x26ge 52 3 in in IN cord-025920-9p5x26ge 52 4 severe severe JJ cord-025920-9p5x26ge 52 5 acute acute JJ cord-025920-9p5x26ge 52 6 respiratory respiratory JJ cord-025920-9p5x26ge 52 7 distress distress NN cord-025920-9p5x26ge 52 8 syndrome syndrome NN cord-025920-9p5x26ge 52 9 Refractory refractory JJ cord-025920-9p5x26ge 52 10 hypoxemia hypoxemia NN cord-025920-9p5x26ge 52 11 and and CC cord-025920-9p5x26ge 52 12 use use NN cord-025920-9p5x26ge 52 13 of of IN cord-025920-9p5x26ge 52 14 rescue rescue NN cord-025920-9p5x26ge 52 15 strategies strategy NNS cord-025920-9p5x26ge 52 16 . . . cord-025920-9p5x26ge 53 1 A a DT cord-025920-9p5x26ge 53 2 U.S. U.S. NNP cord-025920-9p5x26ge 53 3 national national JJ cord-025920-9p5x26ge 53 4 survey survey NN cord-025920-9p5x26ge 53 5 of of IN cord-025920-9p5x26ge 53 6 adult adult NN cord-025920-9p5x26ge 53 7 intensivists intensivist NNS cord-025920-9p5x26ge 53 8 Early early JJ cord-025920-9p5x26ge 53 9 neuromuscular neuromuscular JJ cord-025920-9p5x26ge 53 10 blockade blockade NN cord-025920-9p5x26ge 53 11 in in IN cord-025920-9p5x26ge 53 12 the the DT cord-025920-9p5x26ge 53 13 acute acute JJ cord-025920-9p5x26ge 53 14 respiratory respiratory JJ cord-025920-9p5x26ge 53 15 distress distress NN cord-025920-9p5x26ge 53 16 syndrome syndrome NN cord-025920-9p5x26ge 53 17 Extracorporeal extracorporeal JJ cord-025920-9p5x26ge 53 18 membrane membrane NN cord-025920-9p5x26ge 53 19 oxygenation oxygenation NN cord-025920-9p5x26ge 53 20 for for IN cord-025920-9p5x26ge 53 21 severe severe JJ cord-025920-9p5x26ge 53 22 acute acute JJ cord-025920-9p5x26ge 53 23 respiratory respiratory JJ cord-025920-9p5x26ge 53 24 distress distress NN cord-025920-9p5x26ge 53 25 syndrome syndrome NN cord-025920-9p5x26ge 53 26 Inhaled inhale VBD cord-025920-9p5x26ge 53 27 nitric nitric JJ cord-025920-9p5x26ge 53 28 oxide oxide NN cord-025920-9p5x26ge 53 29 for for IN cord-025920-9p5x26ge 53 30 acute acute JJ cord-025920-9p5x26ge 53 31 respiratory respiratory JJ cord-025920-9p5x26ge 53 32 distress distress NN cord-025920-9p5x26ge 53 33 syndrome syndrome NN cord-025920-9p5x26ge 53 34 ( ( -LRB- cord-025920-9p5x26ge 53 35 ARDS ARDS NNP cord-025920-9p5x26ge 53 36 ) ) -RRB- cord-025920-9p5x26ge 53 37 in in IN cord-025920-9p5x26ge 53 38 children child NNS cord-025920-9p5x26ge 53 39 and and CC cord-025920-9p5x26ge 53 40 adults adult NNS cord-025920-9p5x26ge 54 1 Aerosolized aerosolize VBN cord-025920-9p5x26ge 54 2 prostacyclins prostacyclin NNS cord-025920-9p5x26ge 54 3 for for IN cord-025920-9p5x26ge 54 4 acute acute JJ cord-025920-9p5x26ge 54 5 respiratory respiratory JJ cord-025920-9p5x26ge 54 6 distress distress NN cord-025920-9p5x26ge 54 7 syndrome syndrome NN cord-025920-9p5x26ge 54 8 ( ( -LRB- cord-025920-9p5x26ge 54 9 ARDS ARDS NNP cord-025920-9p5x26ge 54 10 ) ) -RRB- cord-025920-9p5x26ge 55 1 Neuromuscular neuromuscular JJ cord-025920-9p5x26ge 55 2 blockers blocker NNS cord-025920-9p5x26ge 55 3 in in IN cord-025920-9p5x26ge 55 4 early early JJ cord-025920-9p5x26ge 55 5 acute acute JJ cord-025920-9p5x26ge 55 6 respiratory respiratory JJ cord-025920-9p5x26ge 55 7 distress distress NN cord-025920-9p5x26ge 55 8 syndrome syndrome NN cord-025920-9p5x26ge 56 1 A a DT cord-025920-9p5x26ge 56 2 prospective prospective JJ cord-025920-9p5x26ge 56 3 international international JJ cord-025920-9p5x26ge 56 4 observational observational JJ cord-025920-9p5x26ge 56 5 prevalence prevalence NN cord-025920-9p5x26ge 56 6 study study NN cord-025920-9p5x26ge 56 7 on on IN cord-025920-9p5x26ge 56 8 prone prone JJ cord-025920-9p5x26ge 56 9 positioning positioning NN cord-025920-9p5x26ge 56 10 of of IN cord-025920-9p5x26ge 56 11 ARDS ARDS NNP cord-025920-9p5x26ge 56 12 patients patient NNS cord-025920-9p5x26ge 56 13 : : : cord-025920-9p5x26ge 57 1 the the DT cord-025920-9p5x26ge 57 2 APRONET APRONET NNP cord-025920-9p5x26ge 57 3 ( ( -LRB- cord-025920-9p5x26ge 57 4 ARDS ARDS NNP cord-025920-9p5x26ge 57 5 Prone Prone NNP cord-025920-9p5x26ge 57 6 Position Position NNP cord-025920-9p5x26ge 57 7 Network Network NNP cord-025920-9p5x26ge 57 8 ) ) -RRB- cord-025920-9p5x26ge 57 9 study study NN cord-025920-9p5x26ge 57 10 An an DT cord-025920-9p5x26ge 57 11 Official official JJ cord-025920-9p5x26ge 57 12 American American NNP cord-025920-9p5x26ge 57 13 Thoracic Thoracic NNP cord-025920-9p5x26ge 57 14 Society Society NNP cord-025920-9p5x26ge 57 15 / / SYM cord-025920-9p5x26ge 57 16 European European NNP cord-025920-9p5x26ge 57 17 Society Society NNP cord-025920-9p5x26ge 57 18 of of IN cord-025920-9p5x26ge 57 19 Intensive Intensive NNP cord-025920-9p5x26ge 57 20 Care Care NNP cord-025920-9p5x26ge 57 21 Medicine/ Medicine/ NNP cord-025920-9p5x26ge 57 22 Society Society NNP cord-025920-9p5x26ge 57 23 of of IN cord-025920-9p5x26ge 57 24 Critical Critical NNP cord-025920-9p5x26ge 57 25 Care Care NNP cord-025920-9p5x26ge 57 26 Medicine Medicine NNP cord-025920-9p5x26ge 57 27 Clinical Clinical NNP cord-025920-9p5x26ge 57 28 Practice Practice NNP cord-025920-9p5x26ge 57 29 Guideline Guideline NNP cord-025920-9p5x26ge 57 30 : : : cord-025920-9p5x26ge 58 1 mechanical mechanical JJ cord-025920-9p5x26ge 58 2 ventilation ventilation NN cord-025920-9p5x26ge 58 3 in in IN cord-025920-9p5x26ge 58 4 adult adult NN cord-025920-9p5x26ge 58 5 patients patient NNS cord-025920-9p5x26ge 58 6 with with IN cord-025920-9p5x26ge 58 7 acute acute JJ cord-025920-9p5x26ge 58 8 respiratory respiratory JJ cord-025920-9p5x26ge 58 9 distress distress NN cord-025920-9p5x26ge 58 10 syndrome syndrome NN