id	sid	tid	token	lemma	pos
cord-277648-9kxwkcbl	1	1	key	key	NN
cord-277648-9kxwkcbl	1	2	:	:	:
cord-277648-9kxwkcbl	2	1	cord-277648	cord-277648	JJ
cord-277648-9kxwkcbl	2	2	-	-	HYPH
cord-277648-9kxwkcbl	2	3	9kxwkcbl	9kxwkcbl	CD
cord-277648-9kxwkcbl	2	4	authors	author	NNS
cord-277648-9kxwkcbl	2	5	:	:	:
cord-277648-9kxwkcbl	2	6	Overholt	Overholt	NNP
cord-277648-9kxwkcbl	2	7	,	,	,
cord-277648-9kxwkcbl	2	8	Kalon	Kalon	NNP
cord-277648-9kxwkcbl	2	9	J.	J.	NNP
cord-277648-9kxwkcbl	2	10	;	;	:
cord-277648-9kxwkcbl	2	11	Krog	Krog	NNP
cord-277648-9kxwkcbl	2	12	,	,	,
cord-277648-9kxwkcbl	2	13	Jonathan	Jonathan	NNP
cord-277648-9kxwkcbl	2	14	R.	R.	NNP
cord-277648-9kxwkcbl	2	15	;	;	:
cord-277648-9kxwkcbl	2	16	Bryson	Bryson	NNP
cord-277648-9kxwkcbl	2	17	,	,	,
cord-277648-9kxwkcbl	2	18	Bryan	Bryan	NNP
cord-277648-9kxwkcbl	2	19	D.	D.	NNP
cord-277648-9kxwkcbl	2	20	title	title	NN
cord-277648-9kxwkcbl	2	21	:	:	:
cord-277648-9kxwkcbl	2	22	Dissecting	dissect	VBG
cord-277648-9kxwkcbl	2	23	the	the	DT
cord-277648-9kxwkcbl	2	24	common	common	JJ
cord-277648-9kxwkcbl	2	25	and	and	CC
cord-277648-9kxwkcbl	2	26	compartment	compartment	NN
cord-277648-9kxwkcbl	2	27	-	-	HYPH
cord-277648-9kxwkcbl	2	28	specific	specific	JJ
cord-277648-9kxwkcbl	2	29	features	feature	NNS
cord-277648-9kxwkcbl	2	30	of	of	IN
cord-277648-9kxwkcbl	2	31	COVID-19	covid-19	JJ
cord-277648-9kxwkcbl	2	32	severity	severity	NN
cord-277648-9kxwkcbl	2	33	in	in	IN
cord-277648-9kxwkcbl	2	34	the	the	DT
cord-277648-9kxwkcbl	2	35	lung	lung	NN
cord-277648-9kxwkcbl	2	36	and	and	CC
cord-277648-9kxwkcbl	2	37	periphery	periphery	NN
cord-277648-9kxwkcbl	2	38	with	with	IN
cord-277648-9kxwkcbl	2	39	single	single	JJ
cord-277648-9kxwkcbl	2	40	-	-	HYPH
cord-277648-9kxwkcbl	2	41	cell	cell	NN
cord-277648-9kxwkcbl	2	42	resolution	resolution	NN
cord-277648-9kxwkcbl	2	43	date	date	NN
cord-277648-9kxwkcbl	2	44	:	:	:
cord-277648-9kxwkcbl	2	45	2020	2020	CD
cord-277648-9kxwkcbl	2	46	-	-	HYPH
cord-277648-9kxwkcbl	2	47	06	06	CD
cord-277648-9kxwkcbl	2	48	-	-	SYM
cord-277648-9kxwkcbl	2	49	19	19	CD
cord-277648-9kxwkcbl	2	50	journal	journal	NN
cord-277648-9kxwkcbl	2	51	:	:	:
cord-277648-9kxwkcbl	3	1	bioRxiv	biorxiv	IN
cord-277648-9kxwkcbl	3	2	DOI	DOI	NNP
cord-277648-9kxwkcbl	3	3	:	:	:
cord-277648-9kxwkcbl	4	1	10.1101/2020.06.15.147470	10.1101/2020.06.15.147470	LS
cord-277648-9kxwkcbl	5	1	sha	sha	NNP
cord-277648-9kxwkcbl	5	2	:	:	:
cord-277648-9kxwkcbl	6	1	6457c104a7b0b025f7536a24db9a40f663e5f469	6457c104a7b0b025f7536a24db9a40f663e5f469	CD
cord-277648-9kxwkcbl	7	1	doc_id	doc_id	CD
cord-277648-9kxwkcbl	7	2	:	:	:
cord-277648-9kxwkcbl	7	3	277648	277648	CD
cord-277648-9kxwkcbl	7	4	cord_uid	cord_uid	NNS
cord-277648-9kxwkcbl	7	5	:	:	:
cord-277648-9kxwkcbl	8	1	9kxwkcbl	9kxwkcbl	CD
cord-277648-9kxwkcbl	8	2	As	as	IN
cord-277648-9kxwkcbl	8	3	the	the	DT
cord-277648-9kxwkcbl	8	4	global	global	JJ
cord-277648-9kxwkcbl	8	5	COVID-19	COVID-19	NNP
cord-277648-9kxwkcbl	8	6	pandemic	pandemic	NN
cord-277648-9kxwkcbl	8	7	continues	continue	VBZ
cord-277648-9kxwkcbl	8	8	to	to	TO
cord-277648-9kxwkcbl	8	9	escalate	escalate	VB
cord-277648-9kxwkcbl	8	10	,	,	,
cord-277648-9kxwkcbl	8	11	no	no	DT
cord-277648-9kxwkcbl	8	12	effective	effective	JJ
cord-277648-9kxwkcbl	8	13	treatment	treatment	NN
cord-277648-9kxwkcbl	8	14	has	have	VBZ
cord-277648-9kxwkcbl	8	15	yet	yet	RB
cord-277648-9kxwkcbl	8	16	been	be	VBN
cord-277648-9kxwkcbl	8	17	developed	develop	VBN
cord-277648-9kxwkcbl	8	18	for	for	IN
cord-277648-9kxwkcbl	8	19	the	the	DT
cord-277648-9kxwkcbl	8	20	severe	severe	JJ
cord-277648-9kxwkcbl	8	21	respiratory	respiratory	JJ
cord-277648-9kxwkcbl	8	22	complications	complication	NNS
cord-277648-9kxwkcbl	8	23	of	of	IN
cord-277648-9kxwkcbl	8	24	this	this	DT
cord-277648-9kxwkcbl	8	25	disease	disease	NN
cord-277648-9kxwkcbl	8	26	.	.	.
cord-277648-9kxwkcbl	9	1	This	this	DT
cord-277648-9kxwkcbl	9	2	may	may	MD
cord-277648-9kxwkcbl	9	3	be	be	VB
cord-277648-9kxwkcbl	9	4	due	due	JJ
cord-277648-9kxwkcbl	9	5	in	in	IN
cord-277648-9kxwkcbl	9	6	large	large	JJ
cord-277648-9kxwkcbl	9	7	part	part	NN
cord-277648-9kxwkcbl	9	8	to	to	IN
cord-277648-9kxwkcbl	9	9	the	the	DT
cord-277648-9kxwkcbl	9	10	unclear	unclear	JJ
cord-277648-9kxwkcbl	9	11	immunopathological	immunopathological	JJ
cord-277648-9kxwkcbl	9	12	basis	basis	NN
cord-277648-9kxwkcbl	9	13	for	for	IN
cord-277648-9kxwkcbl	9	14	the	the	DT
cord-277648-9kxwkcbl	9	15	development	development	NN
cord-277648-9kxwkcbl	9	16	of	of	IN
cord-277648-9kxwkcbl	9	17	immune	immune	JJ
cord-277648-9kxwkcbl	9	18	dysregulation	dysregulation	NN
cord-277648-9kxwkcbl	9	19	and	and	CC
cord-277648-9kxwkcbl	9	20	acute	acute	JJ
cord-277648-9kxwkcbl	9	21	respiratory	respiratory	JJ
cord-277648-9kxwkcbl	9	22	distress	distress	NN
cord-277648-9kxwkcbl	9	23	syndrome	syndrome	NN
cord-277648-9kxwkcbl	9	24	(	(	-LRB-
cord-277648-9kxwkcbl	9	25	ARDS	ARDS	NNP
cord-277648-9kxwkcbl	9	26	)	)	-RRB-
cord-277648-9kxwkcbl	9	27	in	in	IN
cord-277648-9kxwkcbl	9	28	severe	severe	JJ
cord-277648-9kxwkcbl	9	29	and	and	CC
cord-277648-9kxwkcbl	9	30	critical	critical	JJ
cord-277648-9kxwkcbl	9	31	patients	patient	NNS
cord-277648-9kxwkcbl	9	32	.	.	.
cord-277648-9kxwkcbl	10	1	Specifically	specifically	RB
cord-277648-9kxwkcbl	10	2	,	,	,
cord-277648-9kxwkcbl	10	3	it	-PRON-	PRP
cord-277648-9kxwkcbl	10	4	remains	remain	VBZ
cord-277648-9kxwkcbl	10	5	unknown	unknown	JJ
cord-277648-9kxwkcbl	10	6	whether	whether	IN
cord-277648-9kxwkcbl	10	7	the	the	DT
cord-277648-9kxwkcbl	10	8	immunological	immunological	JJ
cord-277648-9kxwkcbl	10	9	features	feature	NNS
cord-277648-9kxwkcbl	10	10	of	of	IN
cord-277648-9kxwkcbl	10	11	the	the	DT
cord-277648-9kxwkcbl	10	12	disease	disease	NN
cord-277648-9kxwkcbl	10	13	that	that	WDT
cord-277648-9kxwkcbl	10	14	have	have	VBP
cord-277648-9kxwkcbl	10	15	been	be	VBN
cord-277648-9kxwkcbl	10	16	identified	identify	VBN
cord-277648-9kxwkcbl	10	17	so	so	RB
cord-277648-9kxwkcbl	10	18	far	far	RB
cord-277648-9kxwkcbl	10	19	are	be	VBP
cord-277648-9kxwkcbl	10	20	compartment	compartment	NN
cord-277648-9kxwkcbl	10	21	-	-	HYPH
cord-277648-9kxwkcbl	10	22	specific	specific	JJ
cord-277648-9kxwkcbl	10	23	responses	response	NNS
cord-277648-9kxwkcbl	10	24	or	or	CC
cord-277648-9kxwkcbl	10	25	general	general	JJ
cord-277648-9kxwkcbl	10	26	features	feature	NNS
cord-277648-9kxwkcbl	10	27	of	of	IN
cord-277648-9kxwkcbl	10	28	COVID-19	covid-19	NN
cord-277648-9kxwkcbl	10	29	.	.	.
cord-277648-9kxwkcbl	11	1	Additionally	additionally	RB
cord-277648-9kxwkcbl	11	2	,	,	,
cord-277648-9kxwkcbl	11	3	readily	readily	RB
cord-277648-9kxwkcbl	11	4	detectable	detectable	JJ
cord-277648-9kxwkcbl	11	5	biological	biological	JJ
cord-277648-9kxwkcbl	11	6	markers	marker	NNS
cord-277648-9kxwkcbl	11	7	correlated	correlate	VBN
cord-277648-9kxwkcbl	11	8	with	with	IN
cord-277648-9kxwkcbl	11	9	strata	stratum	NNS
cord-277648-9kxwkcbl	11	10	of	of	IN
cord-277648-9kxwkcbl	11	11	disease	disease	NN
cord-277648-9kxwkcbl	11	12	severity	severity	NN
cord-277648-9kxwkcbl	11	13	that	that	WDT
cord-277648-9kxwkcbl	11	14	could	could	MD
cord-277648-9kxwkcbl	11	15	be	be	VB
cord-277648-9kxwkcbl	11	16	used	use	VBN
cord-277648-9kxwkcbl	11	17	to	to	TO
cord-277648-9kxwkcbl	11	18	triage	triage	VB
cord-277648-9kxwkcbl	11	19	patients	patient	NNS
cord-277648-9kxwkcbl	11	20	and	and	CC
cord-277648-9kxwkcbl	11	21	inform	inform	VB
cord-277648-9kxwkcbl	11	22	treatment	treatment	NN
cord-277648-9kxwkcbl	11	23	options	option	NNS
cord-277648-9kxwkcbl	11	24	have	have	VBP
cord-277648-9kxwkcbl	11	25	not	not	RB
cord-277648-9kxwkcbl	11	26	yet	yet	RB
cord-277648-9kxwkcbl	11	27	been	be	VBN
cord-277648-9kxwkcbl	11	28	identified	identify	VBN
cord-277648-9kxwkcbl	11	29	.	.	.
cord-277648-9kxwkcbl	12	1	Here	here	RB
cord-277648-9kxwkcbl	12	2	,	,	,
cord-277648-9kxwkcbl	12	3	we	-PRON-	PRP
cord-277648-9kxwkcbl	12	4	leveraged	leverage	VBD
cord-277648-9kxwkcbl	12	5	publicly	publicly	RB
cord-277648-9kxwkcbl	12	6	available	available	JJ
cord-277648-9kxwkcbl	12	7	single	single	JJ
cord-277648-9kxwkcbl	12	8	-	-	HYPH
cord-277648-9kxwkcbl	12	9	cell	cell	NN
cord-277648-9kxwkcbl	12	10	RNA	rna	NN
cord-277648-9kxwkcbl	12	11	sequencing	sequencing	NN
cord-277648-9kxwkcbl	12	12	data	datum	NNS
cord-277648-9kxwkcbl	12	13	to	to	TO
cord-277648-9kxwkcbl	12	14	elucidate	elucidate	VB
cord-277648-9kxwkcbl	12	15	the	the	DT
cord-277648-9kxwkcbl	12	16	common	common	JJ
cord-277648-9kxwkcbl	12	17	and	and	CC
cord-277648-9kxwkcbl	12	18	compartment	compartment	NN
cord-277648-9kxwkcbl	12	19	-	-	HYPH
cord-277648-9kxwkcbl	12	20	specific	specific	JJ
cord-277648-9kxwkcbl	12	21	immunological	immunological	JJ
cord-277648-9kxwkcbl	12	22	features	feature	NNS
cord-277648-9kxwkcbl	12	23	of	of	IN
cord-277648-9kxwkcbl	12	24	clinically	clinically	RB
cord-277648-9kxwkcbl	12	25	severe	severe	JJ
cord-277648-9kxwkcbl	12	26	COVID-19	covid-19	NN
cord-277648-9kxwkcbl	12	27	.	.	.
cord-277648-9kxwkcbl	13	1	We	-PRON-	PRP
cord-277648-9kxwkcbl	13	2	identified	identify	VBD
cord-277648-9kxwkcbl	13	3	a	a	DT
cord-277648-9kxwkcbl	13	4	number	number	NN
cord-277648-9kxwkcbl	13	5	of	of	IN
cord-277648-9kxwkcbl	13	6	transcriptional	transcriptional	JJ
cord-277648-9kxwkcbl	13	7	programs	program	NNS
cord-277648-9kxwkcbl	13	8	that	that	WDT
cord-277648-9kxwkcbl	13	9	are	be	VBP
cord-277648-9kxwkcbl	13	10	altered	alter	VBN
cord-277648-9kxwkcbl	13	11	across	across	IN
cord-277648-9kxwkcbl	13	12	the	the	DT
cord-277648-9kxwkcbl	13	13	spectrum	spectrum	NN
cord-277648-9kxwkcbl	13	14	of	of	IN
cord-277648-9kxwkcbl	13	15	disease	disease	NN
cord-277648-9kxwkcbl	13	16	severity	severity	NN
cord-277648-9kxwkcbl	13	17	,	,	,
cord-277648-9kxwkcbl	13	18	few	few	JJ
cord-277648-9kxwkcbl	13	19	of	of	IN
cord-277648-9kxwkcbl	13	20	which	which	WDT
cord-277648-9kxwkcbl	13	21	are	be	VBP
cord-277648-9kxwkcbl	13	22	common	common	JJ
cord-277648-9kxwkcbl	13	23	between	between	IN
cord-277648-9kxwkcbl	13	24	the	the	DT
cord-277648-9kxwkcbl	13	25	lung	lung	NN
cord-277648-9kxwkcbl	13	26	and	and	CC
cord-277648-9kxwkcbl	13	27	peripheral	peripheral	JJ
cord-277648-9kxwkcbl	13	28	immune	immune	JJ
cord-277648-9kxwkcbl	13	29	environments	environment	NNS
cord-277648-9kxwkcbl	13	30	.	.	.
cord-277648-9kxwkcbl	14	1	In	in	IN
cord-277648-9kxwkcbl	14	2	the	the	DT
cord-277648-9kxwkcbl	14	3	lung	lung	NN
cord-277648-9kxwkcbl	14	4	,	,	,
cord-277648-9kxwkcbl	14	5	comparing	compare	VBG
cord-277648-9kxwkcbl	14	6	severe	severe	JJ
cord-277648-9kxwkcbl	14	7	and	and	CC
cord-277648-9kxwkcbl	14	8	moderate	moderate	JJ
cord-277648-9kxwkcbl	14	9	patients	patient	NNS
cord-277648-9kxwkcbl	14	10	revealed	reveal	VBD
cord-277648-9kxwkcbl	14	11	severity	severity	NN
cord-277648-9kxwkcbl	14	12	-	-	HYPH
cord-277648-9kxwkcbl	14	13	specific	specific	JJ
cord-277648-9kxwkcbl	14	14	responses	response	NNS
cord-277648-9kxwkcbl	14	15	of	of	IN
cord-277648-9kxwkcbl	14	16	enhanced	enhanced	JJ
cord-277648-9kxwkcbl	14	17	interferon	interferon	NN
cord-277648-9kxwkcbl	14	18	,	,	,
cord-277648-9kxwkcbl	14	19	A20	A20	NNP
cord-277648-9kxwkcbl	14	20	/	/	SYM
cord-277648-9kxwkcbl	14	21	IκB	iκb	NN
cord-277648-9kxwkcbl	14	22	,	,	,
cord-277648-9kxwkcbl	14	23	IL-2	IL-2	NNP
cord-277648-9kxwkcbl	14	24	,	,	,
cord-277648-9kxwkcbl	14	25	and	and	CC
cord-277648-9kxwkcbl	14	26	IL-6	IL-6	NNP
cord-277648-9kxwkcbl	14	27	pathway	pathway	NN
cord-277648-9kxwkcbl	14	28	signatures	signature	NNS
cord-277648-9kxwkcbl	14	29	along	along	IN
cord-277648-9kxwkcbl	14	30	with	with	IN
cord-277648-9kxwkcbl	14	31	broad	broad	JJ
cord-277648-9kxwkcbl	14	32	signaling	signal	VBG
cord-277648-9kxwkcbl	14	33	activity	activity	NN
cord-277648-9kxwkcbl	14	34	of	of	IN
cord-277648-9kxwkcbl	14	35	IFNG	IFNG	NNP
cord-277648-9kxwkcbl	14	36	,	,	,
cord-277648-9kxwkcbl	14	37	SPP1	SPP1	NNPS
cord-277648-9kxwkcbl	14	38	,	,	,
cord-277648-9kxwkcbl	14	39	CCL3	CCL3	NNP
cord-277648-9kxwkcbl	14	40	,	,	,
cord-277648-9kxwkcbl	14	41	CCL8	CCL8	NNP
cord-277648-9kxwkcbl	14	42	,	,	,
cord-277648-9kxwkcbl	14	43	and	and	CC
cord-277648-9kxwkcbl	14	44	IL18	IL18	NNP
cord-277648-9kxwkcbl	14	45	across	across	IN
cord-277648-9kxwkcbl	14	46	cell	cell	NN
cord-277648-9kxwkcbl	14	47	types	type	NNS
cord-277648-9kxwkcbl	14	48	.	.	.
cord-277648-9kxwkcbl	15	1	These	these	DT
cord-277648-9kxwkcbl	15	2	signatures	signature	NNS
cord-277648-9kxwkcbl	15	3	contrasted	contrast	VBN
cord-277648-9kxwkcbl	15	4	with	with	IN
cord-277648-9kxwkcbl	15	5	features	feature	NNS
cord-277648-9kxwkcbl	15	6	unique	unique	JJ
cord-277648-9kxwkcbl	15	7	to	to	IN
cord-277648-9kxwkcbl	15	8	ARDS	ARDS	NNP
cord-277648-9kxwkcbl	15	9	observed	observe	VBD
cord-277648-9kxwkcbl	15	10	in	in	IN
cord-277648-9kxwkcbl	15	11	the	the	DT
cord-277648-9kxwkcbl	15	12	blood	blood	NN
cord-277648-9kxwkcbl	15	13	compartment	compartment	NN
cord-277648-9kxwkcbl	15	14	,	,	,
cord-277648-9kxwkcbl	15	15	which	which	WDT
cord-277648-9kxwkcbl	15	16	included	include	VBD
cord-277648-9kxwkcbl	15	17	depletion	depletion	NN
cord-277648-9kxwkcbl	15	18	of	of	IN
cord-277648-9kxwkcbl	15	19	interferon	interferon	NN
cord-277648-9kxwkcbl	15	20	and	and	CC
cord-277648-9kxwkcbl	15	21	A20	A20	NNP
cord-277648-9kxwkcbl	15	22	/	/	SYM
cord-277648-9kxwkcbl	15	23	IκB	iκb	NN
cord-277648-9kxwkcbl	15	24	signatures	signature	NNS
cord-277648-9kxwkcbl	15	25	and	and	CC
cord-277648-9kxwkcbl	15	26	a	a	DT
cord-277648-9kxwkcbl	15	27	lack	lack	NN
cord-277648-9kxwkcbl	15	28	of	of	IN
cord-277648-9kxwkcbl	15	29	IL-6	IL-6	NNP
cord-277648-9kxwkcbl	15	30	response	response	NN
cord-277648-9kxwkcbl	15	31	.	.	.
cord-277648-9kxwkcbl	16	1	The	the	DT
cord-277648-9kxwkcbl	16	2	cell	cell	NN
cord-277648-9kxwkcbl	16	3	surface	surface	NN
cord-277648-9kxwkcbl	16	4	marker	marker	NN
cord-277648-9kxwkcbl	17	1	S1PR1	S1PR1	NNP
cord-277648-9kxwkcbl	17	2	was	be	VBD
cord-277648-9kxwkcbl	17	3	strongly	strongly	RB
cord-277648-9kxwkcbl	17	4	upregulated	upregulate	VBN
cord-277648-9kxwkcbl	17	5	in	in	IN
cord-277648-9kxwkcbl	17	6	patients	patient	NNS
cord-277648-9kxwkcbl	17	7	diagnosed	diagnose	VBN
cord-277648-9kxwkcbl	17	8	with	with	IN
cord-277648-9kxwkcbl	17	9	ARDS	ARDS	NNP
cord-277648-9kxwkcbl	17	10	compared	compare	VBN
cord-277648-9kxwkcbl	17	11	to	to	IN
cord-277648-9kxwkcbl	17	12	non	non	JJ
cord-277648-9kxwkcbl	17	13	-	-	JJ
cord-277648-9kxwkcbl	17	14	ARDS	ARDS	NNP
cord-277648-9kxwkcbl	17	15	patients	patient	NNS
cord-277648-9kxwkcbl	17	16	in	in	RP
cord-277648-9kxwkcbl	17	17	γδ	γδ	NNP
cord-277648-9kxwkcbl	17	18	T	T	NNP
cord-277648-9kxwkcbl	17	19	cells	cell	NNS
cord-277648-9kxwkcbl	17	20	of	of	IN
cord-277648-9kxwkcbl	17	21	the	the	DT
cord-277648-9kxwkcbl	17	22	blood	blood	NN
cord-277648-9kxwkcbl	17	23	compartment	compartment	NN
cord-277648-9kxwkcbl	17	24	,	,	,
cord-277648-9kxwkcbl	17	25	and	and	CC
cord-277648-9kxwkcbl	17	26	we	-PRON-	PRP
cord-277648-9kxwkcbl	17	27	nominate	nominate	VBP
cord-277648-9kxwkcbl	17	28	S1PR1	S1PR1	NNP
cord-277648-9kxwkcbl	17	29	as	as	IN
cord-277648-9kxwkcbl	17	30	a	a	DT
cord-277648-9kxwkcbl	17	31	potential	potential	JJ
cord-277648-9kxwkcbl	17	32	marker	marker	NN
cord-277648-9kxwkcbl	17	33	for	for	IN
cord-277648-9kxwkcbl	17	34	immunophenotyping	immunophenotype	VBG
cord-277648-9kxwkcbl	17	35	ARDS	ARDS	NNP
cord-277648-9kxwkcbl	17	36	in	in	IN
cord-277648-9kxwkcbl	17	37	COVID-19	COVID-19	NNP
cord-277648-9kxwkcbl	17	38	patients	patient	NNS
cord-277648-9kxwkcbl	17	39	using	use	VBG
cord-277648-9kxwkcbl	17	40	flow	flow	NN
cord-277648-9kxwkcbl	17	41	cytometry	cytometry	NN
cord-277648-9kxwkcbl	17	42	.	.	.
cord-277648-9kxwkcbl	18	1	HIGHLIGHTS	HIGHLIGHTS	NNP
cord-277648-9kxwkcbl	19	1	COVID-19	covid-19	JJ
cord-277648-9kxwkcbl	19	2	disease	disease	NN
cord-277648-9kxwkcbl	19	3	severity	severity	NN
cord-277648-9kxwkcbl	19	4	is	be	VBZ
cord-277648-9kxwkcbl	19	5	associated	associate	VBN
cord-277648-9kxwkcbl	19	6	with	with	IN
cord-277648-9kxwkcbl	19	7	a	a	DT
cord-277648-9kxwkcbl	19	8	number	number	NN
cord-277648-9kxwkcbl	19	9	of	of	IN
cord-277648-9kxwkcbl	19	10	compositional	compositional	JJ
cord-277648-9kxwkcbl	19	11	shifts	shift	NNS
cord-277648-9kxwkcbl	19	12	in	in	IN
cord-277648-9kxwkcbl	19	13	the	the	DT
cord-277648-9kxwkcbl	19	14	cellular	cellular	JJ
cord-277648-9kxwkcbl	19	15	makeup	makeup	NN
cord-277648-9kxwkcbl	19	16	of	of	IN
cord-277648-9kxwkcbl	19	17	the	the	DT
cord-277648-9kxwkcbl	19	18	blood	blood	NN
cord-277648-9kxwkcbl	19	19	and	and	CC
cord-277648-9kxwkcbl	19	20	lung	lung	NN
cord-277648-9kxwkcbl	19	21	environments	environment	NNS
cord-277648-9kxwkcbl	19	22	.	.	.
cord-277648-9kxwkcbl	20	1	Transcriptional	Transcriptional	NNP
cord-277648-9kxwkcbl	20	2	data	datum	NNS
cord-277648-9kxwkcbl	20	3	suggest	suggest	VBP
cord-277648-9kxwkcbl	20	4	differentially	differentially	RB
cord-277648-9kxwkcbl	20	5	expressed	express	VBN
cord-277648-9kxwkcbl	20	6	cell	cell	NN
cord-277648-9kxwkcbl	20	7	surface	surface	NN
cord-277648-9kxwkcbl	20	8	proteins	protein	NNS
cord-277648-9kxwkcbl	20	9	as	as	IN
cord-277648-9kxwkcbl	20	10	markers	marker	NNS
cord-277648-9kxwkcbl	20	11	for	for	IN
cord-277648-9kxwkcbl	20	12	COVID-19	covid-19	JJ
cord-277648-9kxwkcbl	20	13	immunophenotyping	immunophenotyping	NN
cord-277648-9kxwkcbl	20	14	from	from	IN
cord-277648-9kxwkcbl	20	15	BALF	BALF	NNP
cord-277648-9kxwkcbl	20	16	and	and	CC
cord-277648-9kxwkcbl	20	17	PBMC	PBMC	NNP
cord-277648-9kxwkcbl	20	18	samples	sample	NNS
cord-277648-9kxwkcbl	20	19	.	.	.
cord-277648-9kxwkcbl	21	1	Severity	severity	NN
cord-277648-9kxwkcbl	21	2	-	-	HYPH
cord-277648-9kxwkcbl	21	3	specific	specific	JJ
cord-277648-9kxwkcbl	21	4	features	feature	NNS
cord-277648-9kxwkcbl	22	1	COVID-19	covid-19	VB
cord-277648-9kxwkcbl	22	2	manifest	manifest	NN
cord-277648-9kxwkcbl	22	3	at	at	IN
cord-277648-9kxwkcbl	22	4	the	the	DT
cord-277648-9kxwkcbl	22	5	pathway	pathway	NN
cord-277648-9kxwkcbl	22	6	level	level	NN
cord-277648-9kxwkcbl	22	7	,	,	,
cord-277648-9kxwkcbl	22	8	suggesting	suggest	VBG
cord-277648-9kxwkcbl	22	9	distinct	distinct	JJ
cord-277648-9kxwkcbl	22	10	changes	change	NNS
cord-277648-9kxwkcbl	22	11	to	to	IN
cord-277648-9kxwkcbl	22	12	epithelia	epithelium	NNS
cord-277648-9kxwkcbl	22	13	and	and	CC
cord-277648-9kxwkcbl	22	14	differences	difference	NNS
cord-277648-9kxwkcbl	22	15	between	between	IN
cord-277648-9kxwkcbl	22	16	local	local	JJ
cord-277648-9kxwkcbl	22	17	and	and	CC
cord-277648-9kxwkcbl	22	18	systemic	systemic	JJ
cord-277648-9kxwkcbl	22	19	immune	immune	JJ
cord-277648-9kxwkcbl	22	20	dynamics	dynamic	NNS
cord-277648-9kxwkcbl	22	21	.	.	.
cord-277648-9kxwkcbl	23	1	Immune	immune	JJ
cord-277648-9kxwkcbl	23	2	-	-	HYPH
cord-277648-9kxwkcbl	23	3	epithelial	epithelial	JJ
cord-277648-9kxwkcbl	23	4	cellular	cellular	JJ
cord-277648-9kxwkcbl	23	5	communication	communication	NN
cord-277648-9kxwkcbl	23	6	analysis	analysis	NN
cord-277648-9kxwkcbl	23	7	identifies	identify	VBZ
cord-277648-9kxwkcbl	23	8	ligands	ligand	NNS
cord-277648-9kxwkcbl	23	9	implicated	implicate	VBN
cord-277648-9kxwkcbl	23	10	in	in	IN
cord-277648-9kxwkcbl	23	11	transcriptional	transcriptional	JJ
cord-277648-9kxwkcbl	23	12	regulation	regulation	NN
cord-277648-9kxwkcbl	23	13	of	of	IN
cord-277648-9kxwkcbl	23	14	proto	proto	JJ
cord-277648-9kxwkcbl	23	15	-	-	HYPH
cord-277648-9kxwkcbl	23	16	oncogenes	oncogene	NNS
cord-277648-9kxwkcbl	23	17	in	in	IN
cord-277648-9kxwkcbl	23	18	the	the	DT
cord-277648-9kxwkcbl	23	19	lung	lung	NN
cord-277648-9kxwkcbl	23	20	epithelia	epithelium	NNS
cord-277648-9kxwkcbl	23	21	of	of	IN
cord-277648-9kxwkcbl	23	22	severe	severe	JJ
cord-277648-9kxwkcbl	23	23	COVID-19	covid-19	JJ
cord-277648-9kxwkcbl	23	24	patients	patient	NNS
cord-277648-9kxwkcbl	23	25	.	.	.
cord-277648-9kxwkcbl	24	1	Network	network	NN
cord-277648-9kxwkcbl	24	2	analysis	analysis	NN
cord-277648-9kxwkcbl	24	3	suggests	suggest	VBZ
cord-277648-9kxwkcbl	24	4	broadly	broadly	RB
cord-277648-9kxwkcbl	24	5	-	-	HYPH
cord-277648-9kxwkcbl	24	6	acting	act	VBG
cord-277648-9kxwkcbl	24	7	dysregulatory	dysregulatory	JJ
cord-277648-9kxwkcbl	24	8	ligands	ligand	NNS
cord-277648-9kxwkcbl	24	9	in	in	IN
cord-277648-9kxwkcbl	24	10	the	the	DT
cord-277648-9kxwkcbl	24	11	pulmonary	pulmonary	JJ
cord-277648-9kxwkcbl	24	12	microenvironment	microenvironment	NN
cord-277648-9kxwkcbl	24	13	as	as	IN
cord-277648-9kxwkcbl	24	14	candidate	candidate	NN
cord-277648-9kxwkcbl	24	15	therapeutic	therapeutic	JJ
cord-277648-9kxwkcbl	24	16	targets	target	NNS
cord-277648-9kxwkcbl	24	17	for	for	IN
cord-277648-9kxwkcbl	24	18	the	the	DT
cord-277648-9kxwkcbl	24	19	treatment	treatment	NN
cord-277648-9kxwkcbl	24	20	of	of	IN
cord-277648-9kxwkcbl	24	21	severe	severe	JJ
cord-277648-9kxwkcbl	24	22	COVID-19	covid-19	NN
cord-277648-9kxwkcbl	24	23	.	.	.
cord-277648-9kxwkcbl	25	1	December	December	NNP
cord-277648-9kxwkcbl	25	2	2019	2019	CD
cord-277648-9kxwkcbl	25	3	,	,	,
cord-277648-9kxwkcbl	25	4	the	the	DT
cord-277648-9kxwkcbl	25	5	virus	virus	NN
cord-277648-9kxwkcbl	25	6	had	have	VBD
cord-277648-9kxwkcbl	25	7	spread	spread	VBN
cord-277648-9kxwkcbl	25	8	to	to	IN
cord-277648-9kxwkcbl	25	9	every	every	DT
cord-277648-9kxwkcbl	25	10	major	major	JJ
cord-277648-9kxwkcbl	25	11	country	country	NN
cord-277648-9kxwkcbl	25	12	on	on	IN
cord-277648-9kxwkcbl	25	13	Earth	Earth	NNP
cord-277648-9kxwkcbl	25	14	[	[	-LRB-
cord-277648-9kxwkcbl	25	15	1	1	CD
cord-277648-9kxwkcbl	25	16	,	,	,
cord-277648-9kxwkcbl	25	17	2	2	CD
cord-277648-9kxwkcbl	25	18	,	,	,
cord-277648-9kxwkcbl	25	19	3	3	CD
cord-277648-9kxwkcbl	25	20	,	,	,
cord-277648-9kxwkcbl	25	21	4	4	CD
cord-277648-9kxwkcbl	25	22	]	]	-RRB-
cord-277648-9kxwkcbl	25	23	.	.	.
cord-277648-9kxwkcbl	26	1	The	the	DT
cord-277648-9kxwkcbl	26	2	pandemic	pandemic	NN
cord-277648-9kxwkcbl	26	3	disease	disease	NN
cord-277648-9kxwkcbl	26	4	caused	cause	VBN
cord-277648-9kxwkcbl	26	5	by	by	IN
cord-277648-9kxwkcbl	26	6	SARS	SARS	NNP
cord-277648-9kxwkcbl	26	7	-	-	HYPH
cord-277648-9kxwkcbl	26	8	CoV-2	CoV-2	NNP
cord-277648-9kxwkcbl	26	9	,	,	,
cord-277648-9kxwkcbl	26	10	termed	term	VBD
cord-277648-9kxwkcbl	26	11	coronavirus	coronavirus	NN
cord-277648-9kxwkcbl	26	12	disease	disease	NN
cord-277648-9kxwkcbl	26	13	2019	2019	CD
cord-277648-9kxwkcbl	27	1	(	(	-LRB-
cord-277648-9kxwkcbl	27	2	COVID-	COVID-	NNP
cord-277648-9kxwkcbl	27	3	19	19	CD
cord-277648-9kxwkcbl	27	4	)	)	-RRB-
cord-277648-9kxwkcbl	27	5	,	,	,
cord-277648-9kxwkcbl	27	6	has	have	VBZ
cord-277648-9kxwkcbl	27	7	diverse	diverse	JJ
cord-277648-9kxwkcbl	27	8	clinical	clinical	JJ
cord-277648-9kxwkcbl	27	9	presentations	presentation	NNS
cord-277648-9kxwkcbl	27	10	ranging	range	VBG
cord-277648-9kxwkcbl	27	11	from	from	IN
cord-277648-9kxwkcbl	27	12	asymptomatic	asymptomatic	JJ
cord-277648-9kxwkcbl	27	13	infection	infection	NN
cord-277648-9kxwkcbl	27	14	,	,	,
cord-277648-9kxwkcbl	27	15	to	to	TO
cord-277648-9kxwkcbl	27	16	moderate	moderate	VB
cord-277648-9kxwkcbl	27	17	symptomatic	symptomatic	JJ
cord-277648-9kxwkcbl	27	18	infection	infection	NN
cord-277648-9kxwkcbl	27	19	with	with	IN
cord-277648-9kxwkcbl	27	20	possible	possible	JJ
cord-277648-9kxwkcbl	27	21	pneumonia	pneumonia	NN
cord-277648-9kxwkcbl	27	22	,	,	,
cord-277648-9kxwkcbl	27	23	to	to	IN
cord-277648-9kxwkcbl	27	24	severe	severe	JJ
cord-277648-9kxwkcbl	27	25	respiratory	respiratory	JJ
cord-277648-9kxwkcbl	27	26	distress	distress	NN
cord-277648-9kxwkcbl	27	27	,	,	,
cord-277648-9kxwkcbl	27	28	to	to	IN
cord-277648-9kxwkcbl	27	29	critical	critical	JJ
cord-277648-9kxwkcbl	27	30	respiratory	respiratory	JJ
cord-277648-9kxwkcbl	27	31	failure	failure	NN
cord-277648-9kxwkcbl	27	32	,	,	,
cord-277648-9kxwkcbl	27	33	septic	septic	JJ
cord-277648-9kxwkcbl	27	34	shock	shock	NN
cord-277648-9kxwkcbl	27	35	,	,	,
cord-277648-9kxwkcbl	27	36	and/or	and/or	CC
cord-277648-9kxwkcbl	27	37	multiple	multiple	JJ
cord-277648-9kxwkcbl	27	38	organ	organ	NN
cord-277648-9kxwkcbl	27	39	dysfunction	dysfunction	NN
cord-277648-9kxwkcbl	27	40	or	or	CC
cord-277648-9kxwkcbl	27	41	failure	failure	NN
cord-277648-9kxwkcbl	27	42	[	[	-LRB-
cord-277648-9kxwkcbl	27	43	1	1	CD
cord-277648-9kxwkcbl	27	44	,	,	,
cord-277648-9kxwkcbl	27	45	4	4	CD
cord-277648-9kxwkcbl	27	46	,	,	,
cord-277648-9kxwkcbl	27	47	5	5	CD
cord-277648-9kxwkcbl	27	48	,	,	,
cord-277648-9kxwkcbl	27	49	6	6	CD
cord-277648-9kxwkcbl	27	50	]	]	-RRB-
cord-277648-9kxwkcbl	27	51	.	.	.
cord-277648-9kxwkcbl	28	1	A	a	DT
cord-277648-9kxwkcbl	28	2	hallmark	hallmark	NN
cord-277648-9kxwkcbl	28	3	of	of	IN
cord-277648-9kxwkcbl	28	4	severe	severe	JJ
cord-277648-9kxwkcbl	28	5	and	and	CC
cord-277648-9kxwkcbl	28	6	critical	critical	JJ
cord-277648-9kxwkcbl	29	1	COVID-19	covid-19	JJ
cord-277648-9kxwkcbl	29	2	cases	case	NNS
cord-277648-9kxwkcbl	29	3	is	be	VBZ
cord-277648-9kxwkcbl	29	4	a	a	DT
cord-277648-9kxwkcbl	29	5	rampant	rampant	JJ
cord-277648-9kxwkcbl	29	6	dysregulation	dysregulation	NN
cord-277648-9kxwkcbl	29	7	of	of	IN
cord-277648-9kxwkcbl	29	8	the	the	DT
cord-277648-9kxwkcbl	29	9	immune	immune	JJ
cord-277648-9kxwkcbl	29	10	system	system	NN
cord-277648-9kxwkcbl	29	11	concomitant	concomitant	JJ
cord-277648-9kxwkcbl	29	12	with	with	IN
cord-277648-9kxwkcbl	29	13	the	the	DT
cord-277648-9kxwkcbl	29	14	development	development	NN
cord-277648-9kxwkcbl	29	15	of	of	IN
cord-277648-9kxwkcbl	29	16	a	a	DT
cord-277648-9kxwkcbl	29	17	hypoxemic	hypoxemic	JJ
cord-277648-9kxwkcbl	29	18	respiratory	respiratory	JJ
cord-277648-9kxwkcbl	29	19	condition	condition	NN
cord-277648-9kxwkcbl	29	20	widely	widely	RB
cord-277648-9kxwkcbl	29	21	characterized	characterize	VBN
cord-277648-9kxwkcbl	29	22	as	as	IN
cord-277648-9kxwkcbl	29	23	acute	acute	JJ
cord-277648-9kxwkcbl	29	24	respiratory	respiratory	JJ
cord-277648-9kxwkcbl	29	25	distress	distress	NN
cord-277648-9kxwkcbl	29	26	syndrome	syndrome	NN
cord-277648-9kxwkcbl	29	27	(	(	-LRB-
cord-277648-9kxwkcbl	29	28	ARDS	ARDS	NNP
cord-277648-9kxwkcbl	29	29	)	)	-RRB-
cord-277648-9kxwkcbl	29	30	[	[	-LRB-
cord-277648-9kxwkcbl	29	31	1	1	CD
cord-277648-9kxwkcbl	29	32	,	,	,
cord-277648-9kxwkcbl	29	33	7	7	CD
cord-277648-9kxwkcbl	29	34	,	,	,
cord-277648-9kxwkcbl	29	35	8	8	CD
cord-277648-9kxwkcbl	29	36	,	,	,
cord-277648-9kxwkcbl	29	37	9	9	CD
cord-277648-9kxwkcbl	29	38	,	,	,
cord-277648-9kxwkcbl	29	39	10	10	CD
cord-277648-9kxwkcbl	29	40	]	]	-RRB-
cord-277648-9kxwkcbl	29	41	.	.	.
cord-277648-9kxwkcbl	30	1	The	the	DT
cord-277648-9kxwkcbl	30	2	serological	serological	JJ
cord-277648-9kxwkcbl	30	3	profile	profile	NN
cord-277648-9kxwkcbl	30	4	of	of	IN
cord-277648-9kxwkcbl	30	5	severe	severe	JJ
cord-277648-9kxwkcbl	30	6	COVID-19	covid-19	JJ
cord-277648-9kxwkcbl	30	7	patients	patient	NNS
cord-277648-9kxwkcbl	30	8	largely	largely	RB
cord-277648-9kxwkcbl	30	9	resembles	resemble	VBZ
cord-277648-9kxwkcbl	30	10	the	the	DT
cord-277648-9kxwkcbl	30	11	cytokine	cytokine	NN
cord-277648-9kxwkcbl	30	12	profile	profile	NN
cord-277648-9kxwkcbl	30	13	of	of	IN
cord-277648-9kxwkcbl	30	14	ARDS	ARDS	NNP
cord-277648-9kxwkcbl	30	15	[	[	-LRB-
cord-277648-9kxwkcbl	30	16	9	9	CD
cord-277648-9kxwkcbl	30	17	]	]	-RRB-
cord-277648-9kxwkcbl	30	18	and	and	CC
cord-277648-9kxwkcbl	30	19	has	have	VBZ
cord-277648-9kxwkcbl	30	20	been	be	VBN
cord-277648-9kxwkcbl	30	21	characterized	characterize	VBN
cord-277648-9kxwkcbl	30	22	by	by	IN
cord-277648-9kxwkcbl	30	23	high	high	JJ
cord-277648-9kxwkcbl	30	24	levels	level	NNS
cord-277648-9kxwkcbl	30	25	of	of	IN
cord-277648-9kxwkcbl	30	26	many	many	JJ
cord-277648-9kxwkcbl	30	27	cytokines	cytokine	NNS
cord-277648-9kxwkcbl	30	28	including	include	VBG
cord-277648-9kxwkcbl	30	29	IL-2	IL-2	NNP
cord-277648-9kxwkcbl	30	30	,	,	,
cord-277648-9kxwkcbl	30	31	IL-6	IL-6	NNP
cord-277648-9kxwkcbl	30	32	,	,	,
cord-277648-9kxwkcbl	30	33	IL-7	IL-7	NNP
cord-277648-9kxwkcbl	30	34	,	,	,
cord-277648-9kxwkcbl	30	35	IL-8	IL-8	NNP
cord-277648-9kxwkcbl	30	36	,	,	,
cord-277648-9kxwkcbl	30	37	IL-18	IL-18	NNP
cord-277648-9kxwkcbl	30	38	,	,	,
cord-277648-9kxwkcbl	30	39	CCL2	CCL2	NNP
cord-277648-9kxwkcbl	30	40	,	,	,
cord-277648-9kxwkcbl	30	41	CCL8	CCL8	NNP
cord-277648-9kxwkcbl	30	42	,	,	,
cord-277648-9kxwkcbl	30	43	TNF	TNF	NNP
cord-277648-9kxwkcbl	30	44	-	-	HYPH
cord-277648-9kxwkcbl	30	45	α	α	NNP
cord-277648-9kxwkcbl	30	46	,	,	,
cord-277648-9kxwkcbl	30	47	and	and	CC
cord-277648-9kxwkcbl	30	48	IFN	IFN	NNP
cord-277648-9kxwkcbl	30	49	-	-	HYPH
cord-277648-9kxwkcbl	30	50	γ	γ	NNP
cord-277648-9kxwkcbl	30	51	[	[	-LRB-
cord-277648-9kxwkcbl	30	52	9	9	CD
cord-277648-9kxwkcbl	30	53	,	,	,
cord-277648-9kxwkcbl	30	54	11	11	CD
cord-277648-9kxwkcbl	30	55	,	,	,
cord-277648-9kxwkcbl	30	56	12	12	CD
cord-277648-9kxwkcbl	30	57	,	,	,
cord-277648-9kxwkcbl	30	58	13	13	CD
cord-277648-9kxwkcbl	30	59	,	,	,
cord-277648-9kxwkcbl	30	60	14	14	CD
cord-277648-9kxwkcbl	30	61	]	]	-RRB-
cord-277648-9kxwkcbl	30	62	.	.	.
cord-277648-9kxwkcbl	31	1	Post	post	JJ
cord-277648-9kxwkcbl	31	2	-	-	JJ
cord-277648-9kxwkcbl	31	3	mortem	mortem	JJ
cord-277648-9kxwkcbl	31	4	examinations	examination	NNS
cord-277648-9kxwkcbl	31	5	of	of	IN
cord-277648-9kxwkcbl	31	6	COVID-19	covid-19	CD
cord-277648-9kxwkcbl	31	7	patients	patient	NNS
cord-277648-9kxwkcbl	31	8	reveal	reveal	VBP
cord-277648-9kxwkcbl	31	9	the	the	DT
cord-277648-9kxwkcbl	31	10	aftermath	aftermath	NN
cord-277648-9kxwkcbl	31	11	of	of	IN
cord-277648-9kxwkcbl	31	12	these	these	DT
cord-277648-9kxwkcbl	31	13	disease	disease	NN
cord-277648-9kxwkcbl	31	14	dynamics	dynamic	NNS
cord-277648-9kxwkcbl	31	15	:	:	:
cord-277648-9kxwkcbl	31	16	diffuse	diffuse	VB
cord-277648-9kxwkcbl	31	17	alveolar	alveolar	NN
cord-277648-9kxwkcbl	31	18	damage	damage	NN
cord-277648-9kxwkcbl	31	19	,	,	,
cord-277648-9kxwkcbl	31	20	multi	multi	JJ
cord-277648-9kxwkcbl	31	21	-	-	JJ
cord-277648-9kxwkcbl	31	22	organ	organ	JJ
cord-277648-9kxwkcbl	31	23	infiltration	infiltration	NN
cord-277648-9kxwkcbl	31	24	of	of	IN
cord-277648-9kxwkcbl	31	25	lymphocytes	lymphocyte	NNS
cord-277648-9kxwkcbl	31	26	and	and	CC
cord-277648-9kxwkcbl	31	27	alveolar	alveolar	NN
cord-277648-9kxwkcbl	31	28	macrophages	macrophage	NNS
cord-277648-9kxwkcbl	31	29	[	[	-LRB-
cord-277648-9kxwkcbl	31	30	1	1	CD
cord-277648-9kxwkcbl	31	31	,	,	,
cord-277648-9kxwkcbl	31	32	7	7	CD
cord-277648-9kxwkcbl	31	33	,	,	,
cord-277648-9kxwkcbl	31	34	15	15	CD
cord-277648-9kxwkcbl	31	35	,	,	,
cord-277648-9kxwkcbl	31	36	16	16	CD
cord-277648-9kxwkcbl	31	37	]	]	-RRB-
cord-277648-9kxwkcbl	31	38	,	,	,
cord-277648-9kxwkcbl	31	39	and	and	CC
cord-277648-9kxwkcbl	31	40	pneumocyte	pneumocyte	NNP
cord-277648-9kxwkcbl	31	41	hyperplasia	hyperplasia	NNP
cord-277648-9kxwkcbl	31	42	and	and	CC
cord-277648-9kxwkcbl	31	43	peribronchiolar	peribronchiolar	NNP
cord-277648-9kxwkcbl	31	44	metaplasia	metaplasia	FW
cord-277648-9kxwkcbl	31	45	in	in	IN
cord-277648-9kxwkcbl	31	46	the	the	DT
cord-277648-9kxwkcbl	31	47	epithelium	epithelium	NN
cord-277648-9kxwkcbl	31	48	resembling	resemble	VBG
cord-277648-9kxwkcbl	31	49	adenocarcinomas	adenocarcinomas	NNP
cord-277648-9kxwkcbl	31	50	[	[	-LRB-
cord-277648-9kxwkcbl	31	51	15	15	CD
cord-277648-9kxwkcbl	31	52	,	,	,
cord-277648-9kxwkcbl	31	53	16	16	CD
cord-277648-9kxwkcbl	31	54	,	,	,
cord-277648-9kxwkcbl	31	55	17	17	CD
cord-277648-9kxwkcbl	31	56	]	]	-RRB-
cord-277648-9kxwkcbl	31	57	.	.	.
cord-277648-9kxwkcbl	32	1	These	these	DT
cord-277648-9kxwkcbl	32	2	morphological	morphological	JJ
cord-277648-9kxwkcbl	32	3	findings	finding	NNS
cord-277648-9kxwkcbl	32	4	suggest	suggest	VBP
cord-277648-9kxwkcbl	32	5	local	local	JJ
cord-277648-9kxwkcbl	32	6	and	and	CC
cord-277648-9kxwkcbl	32	7	systemic	systemic	JJ
cord-277648-9kxwkcbl	32	8	activation	activation	NN
cord-277648-9kxwkcbl	32	9	and	and	CC
cord-277648-9kxwkcbl	32	10	infiltration	infiltration	NN
cord-277648-9kxwkcbl	32	11	of	of	IN
cord-277648-9kxwkcbl	32	12	inflammatory	inflammatory	JJ
cord-277648-9kxwkcbl	32	13	immune	immune	JJ
cord-277648-9kxwkcbl	32	14	cells	cell	NNS
cord-277648-9kxwkcbl	32	15	that	that	WDT
cord-277648-9kxwkcbl	32	16	may	may	MD
cord-277648-9kxwkcbl	32	17	contribute	contribute	VB
cord-277648-9kxwkcbl	32	18	to	to	IN
cord-277648-9kxwkcbl	32	19	the	the	DT
cord-277648-9kxwkcbl	32	20	inflammatory	inflammatory	JJ
cord-277648-9kxwkcbl	32	21	injuries	injury	NNS
cord-277648-9kxwkcbl	32	22	of	of	IN
cord-277648-9kxwkcbl	32	23	the	the	DT
cord-277648-9kxwkcbl	32	24	respiratory	respiratory	JJ
cord-277648-9kxwkcbl	32	25	system	system	NN
cord-277648-9kxwkcbl	32	26	consistent	consistent	JJ
cord-277648-9kxwkcbl	32	27	with	with	IN
cord-277648-9kxwkcbl	32	28	ARDS	ARDS	NNP
cord-277648-9kxwkcbl	32	29	phenotypes	phenotype	NNS
cord-277648-9kxwkcbl	32	30	in	in	IN
cord-277648-9kxwkcbl	32	31	severe	severe	JJ
cord-277648-9kxwkcbl	32	32	COVID-19	covid-19	NN
cord-277648-9kxwkcbl	32	33	[	[	-LRB-
cord-277648-9kxwkcbl	32	34	15	15	CD
cord-277648-9kxwkcbl	32	35	]	]	-RRB-
cord-277648-9kxwkcbl	32	36	.	.	.
cord-277648-9kxwkcbl	33	1	While	while	IN
cord-277648-9kxwkcbl	33	2	months	month	NNS
cord-277648-9kxwkcbl	33	3	of	of	IN
cord-277648-9kxwkcbl	33	4	clinical	clinical	JJ
cord-277648-9kxwkcbl	33	5	observations	observation	NNS
cord-277648-9kxwkcbl	33	6	in	in	IN
cord-277648-9kxwkcbl	33	7	hospitals	hospital	NNS
cord-277648-9kxwkcbl	33	8	across	across	IN
cord-277648-9kxwkcbl	33	9	the	the	DT
cord-277648-9kxwkcbl	33	10	world	world	NN
cord-277648-9kxwkcbl	33	11	have	have	VBP
cord-277648-9kxwkcbl	33	12	led	lead	VBN
cord-277648-9kxwkcbl	33	13	to	to	IN
cord-277648-9kxwkcbl	33	14	consistent	consistent	JJ
cord-277648-9kxwkcbl	33	15	descriptions	description	NNS
cord-277648-9kxwkcbl	33	16	of	of	IN
cord-277648-9kxwkcbl	33	17	COVID-19	covid-19	JJ
cord-277648-9kxwkcbl	33	18	severity	severity	NN
cord-277648-9kxwkcbl	33	19	at	at	IN
cord-277648-9kxwkcbl	33	20	a	a	DT
cord-277648-9kxwkcbl	33	21	clinical	clinical	JJ
cord-277648-9kxwkcbl	33	22	level	level	NN
cord-277648-9kxwkcbl	33	23	[	[	-LRB-
cord-277648-9kxwkcbl	33	24	18	18	CD
cord-277648-9kxwkcbl	33	25	,	,	,
cord-277648-9kxwkcbl	33	26	19	19	CD
cord-277648-9kxwkcbl	33	27	,	,	,
cord-277648-9kxwkcbl	33	28	20	20	CD
cord-277648-9kxwkcbl	33	29	]	]	-RRB-
cord-277648-9kxwkcbl	33	30	,	,	,
cord-277648-9kxwkcbl	33	31	the	the	DT
cord-277648-9kxwkcbl	33	32	biological	biological	JJ
cord-277648-9kxwkcbl	33	33	underpinnings	underpinning	NNS
cord-277648-9kxwkcbl	33	34	of	of	IN
cord-277648-9kxwkcbl	33	35	immune	immune	JJ
cord-277648-9kxwkcbl	33	36	hyperactivation	hyperactivation	NN
cord-277648-9kxwkcbl	33	37	in	in	IN
cord-277648-9kxwkcbl	33	38	severe	severe	JJ
cord-277648-9kxwkcbl	33	39	and	and	CC
cord-277648-9kxwkcbl	33	40	critical	critical	JJ
cord-277648-9kxwkcbl	33	41	COVID-19	covid-19	NN
cord-277648-9kxwkcbl	33	42	are	be	VBP
cord-277648-9kxwkcbl	33	43	only	only	RB
cord-277648-9kxwkcbl	33	44	beginning	begin	VBG
cord-277648-9kxwkcbl	33	45	to	to	TO
cord-277648-9kxwkcbl	33	46	be	be	VB
cord-277648-9kxwkcbl	33	47	defined	define	VBN
cord-277648-9kxwkcbl	33	48	.	.	.
cord-277648-9kxwkcbl	34	1	Bulk	Bulk	NNP
cord-277648-9kxwkcbl	34	2	RNA	RNA	NNP
cord-277648-9kxwkcbl	34	3	sequencing	sequencing	NN
cord-277648-9kxwkcbl	34	4	(	(	-LRB-
cord-277648-9kxwkcbl	34	5	bulk	bulk	NNP
cord-277648-9kxwkcbl	34	6	RNA	RNA	NNP
cord-277648-9kxwkcbl	34	7	-	-	HYPH
cord-277648-9kxwkcbl	34	8	seq	seq	NNP
cord-277648-9kxwkcbl	34	9	)	)	-RRB-
cord-277648-9kxwkcbl	34	10	and	and	CC
cord-277648-9kxwkcbl	34	11	single	single	JJ
cord-277648-9kxwkcbl	34	12	-	-	HYPH
cord-277648-9kxwkcbl	34	13	cell	cell	NN
cord-277648-9kxwkcbl	34	14	RNA	rna	NN
cord-277648-9kxwkcbl	34	15	sequencing	sequencing	NN
cord-277648-9kxwkcbl	34	16	(	(	-LRB-
cord-277648-9kxwkcbl	34	17	scRNA	scRNA	NNP
cord-277648-9kxwkcbl	34	18	-	-	HYPH
cord-277648-9kxwkcbl	34	19	seq	seq	NN
cord-277648-9kxwkcbl	34	20	)	)	-RRB-
cord-277648-9kxwkcbl	34	21	studies	study	NNS
cord-277648-9kxwkcbl	34	22	have	have	VBP
cord-277648-9kxwkcbl	34	23	identified	identify	VBN
cord-277648-9kxwkcbl	34	24	stark	stark	JJ
cord-277648-9kxwkcbl	34	25	transcriptional	transcriptional	JJ
cord-277648-9kxwkcbl	34	26	differences	difference	NNS
cord-277648-9kxwkcbl	34	27	between	between	IN
cord-277648-9kxwkcbl	34	28	bronchoalveolar	bronchoalveolar	NNP
cord-277648-9kxwkcbl	34	29	lavage	lavage	NN
cord-277648-9kxwkcbl	34	30	fluid	fluid	NN
cord-277648-9kxwkcbl	34	31	(	(	-LRB-
cord-277648-9kxwkcbl	34	32	BALF	BALF	NNP
cord-277648-9kxwkcbl	34	33	)	)	-RRB-
cord-277648-9kxwkcbl	34	34	and	and	CC
cord-277648-9kxwkcbl	34	35	peripheral	peripheral	JJ
cord-277648-9kxwkcbl	34	36	blood	blood	NN
cord-277648-9kxwkcbl	34	37	mononuclear	mononuclear	JJ
cord-277648-9kxwkcbl	34	38	cell	cell	NN
cord-277648-9kxwkcbl	34	39	(	(	-LRB-
cord-277648-9kxwkcbl	34	40	PBMC	PBMC	NNP
cord-277648-9kxwkcbl	34	41	)	)	-RRB-
cord-277648-9kxwkcbl	34	42	samples	sample	NNS
cord-277648-9kxwkcbl	34	43	in	in	IN
cord-277648-9kxwkcbl	34	44	hospitalized	hospitalize	VBN
cord-277648-9kxwkcbl	34	45	COVID-19	covid-19	CD
cord-277648-9kxwkcbl	34	46	patients	patient	NNS
cord-277648-9kxwkcbl	34	47	,	,	,
cord-277648-9kxwkcbl	34	48	indicating	indicate	VBG
cord-277648-9kxwkcbl	34	49	that	that	IN
cord-277648-9kxwkcbl	34	50	immunological	immunological	JJ
cord-277648-9kxwkcbl	34	51	responses	response	NNS
cord-277648-9kxwkcbl	34	52	may	may	MD
cord-277648-9kxwkcbl	34	53	be	be	VB
cord-277648-9kxwkcbl	34	54	highly	highly	RB
cord-277648-9kxwkcbl	34	55	compartment	compartment	NN
cord-277648-9kxwkcbl	34	56	-	-	HYPH
cord-277648-9kxwkcbl	34	57	specific	specific	JJ
cord-277648-9kxwkcbl	34	58	[	[	-LRB-
cord-277648-9kxwkcbl	34	59	21	21	CD
cord-277648-9kxwkcbl	34	60	,	,	,
cord-277648-9kxwkcbl	34	61	22	22	CD
cord-277648-9kxwkcbl	34	62	]	]	-RRB-
cord-277648-9kxwkcbl	34	63	.	.	.
cord-277648-9kxwkcbl	35	1	A	a	DT
cord-277648-9kxwkcbl	35	2	number	number	NN
cord-277648-9kxwkcbl	35	3	of	of	IN
cord-277648-9kxwkcbl	35	4	recent	recent	JJ
cord-277648-9kxwkcbl	35	5	studies	study	NNS
cord-277648-9kxwkcbl	35	6	have	have	VBP
cord-277648-9kxwkcbl	35	7	compared	compare	VBN
cord-277648-9kxwkcbl	35	8	severe	severe	JJ
cord-277648-9kxwkcbl	35	9	patients	patient	NNS
cord-277648-9kxwkcbl	35	10	to	to	IN
cord-277648-9kxwkcbl	35	11	healthy	healthy	JJ
cord-277648-9kxwkcbl	35	12	control	control	NN
cord-277648-9kxwkcbl	35	13	subjects	subject	NNS
cord-277648-9kxwkcbl	35	14	in	in	IN
cord-277648-9kxwkcbl	35	15	an	an	DT
cord-277648-9kxwkcbl	35	16	effort	effort	NN
cord-277648-9kxwkcbl	35	17	to	to	TO
cord-277648-9kxwkcbl	35	18	define	define	VB
cord-277648-9kxwkcbl	35	19	immunological	immunological	JJ
cord-277648-9kxwkcbl	35	20	hallmarks	hallmark	NNS
cord-277648-9kxwkcbl	35	21	of	of	IN
cord-277648-9kxwkcbl	35	22	disease	disease	NN
cord-277648-9kxwkcbl	35	23	severity	severity	NN
cord-277648-9kxwkcbl	35	24	in	in	IN
cord-277648-9kxwkcbl	35	25	both	both	CC
cord-277648-9kxwkcbl	35	26	the	the	DT
cord-277648-9kxwkcbl	35	27	lung	lung	NN
cord-277648-9kxwkcbl	35	28	and	and	CC
cord-277648-9kxwkcbl	35	29	peripheral	peripheral	JJ
cord-277648-9kxwkcbl	35	30	circulation	circulation	NN
cord-277648-9kxwkcbl	35	31	using	use	VBG
cord-277648-9kxwkcbl	35	32	scRNA	scRNA	NNP
cord-277648-9kxwkcbl	35	33	-	-	HYPH
cord-277648-9kxwkcbl	35	34	seq	seq	NN
cord-277648-9kxwkcbl	35	35	.	.	.
cord-277648-9kxwkcbl	36	1	These	these	DT
cord-277648-9kxwkcbl	36	2	studies	study	NNS
cord-277648-9kxwkcbl	36	3	have	have	VBP
cord-277648-9kxwkcbl	36	4	identified	identify	VBN
cord-277648-9kxwkcbl	36	5	that	that	IN
cord-277648-9kxwkcbl	36	6	severe	severe	JJ
cord-277648-9kxwkcbl	36	7	disease	disease	NN
cord-277648-9kxwkcbl	36	8	in	in	IN
cord-277648-9kxwkcbl	36	9	the	the	DT
cord-277648-9kxwkcbl	36	10	lung	lung	NN
cord-277648-9kxwkcbl	36	11	compartment	compartment	NN
cord-277648-9kxwkcbl	36	12	is	be	VBZ
cord-277648-9kxwkcbl	36	13	associated	associate	VBN
cord-277648-9kxwkcbl	36	14	with	with	IN
cord-277648-9kxwkcbl	36	15	lymphopenia	lymphopenia	NNP
cord-277648-9kxwkcbl	36	16	,	,	,
cord-277648-9kxwkcbl	36	17	T	T	NNP
cord-277648-9kxwkcbl	36	18	cell	cell	NN
cord-277648-9kxwkcbl	36	19	hyperactivation	hyperactivation	NN
cord-277648-9kxwkcbl	36	20	,	,	,
cord-277648-9kxwkcbl	36	21	and	and	CC
cord-277648-9kxwkcbl	36	22	inflammatory	inflammatory	JJ
cord-277648-9kxwkcbl	36	23	macrophage	macrophage	NN
cord-277648-9kxwkcbl	36	24	polarization	polarization	NN
cord-277648-9kxwkcbl	36	25	,	,	,
cord-277648-9kxwkcbl	36	26	while	while	IN
cord-277648-9kxwkcbl	36	27	severe	severe	JJ
cord-277648-9kxwkcbl	36	28	disease	disease	NN
cord-277648-9kxwkcbl	36	29	in	in	IN
cord-277648-9kxwkcbl	36	30	the	the	DT
cord-277648-9kxwkcbl	36	31	blood	blood	NN
cord-277648-9kxwkcbl	36	32	is	be	VBZ
cord-277648-9kxwkcbl	36	33	associated	associate	VBN
cord-277648-9kxwkcbl	36	34	with	with	IN
cord-277648-9kxwkcbl	36	35	lymphopenia	lymphopenia	NNP
cord-277648-9kxwkcbl	36	36	,	,	,
cord-277648-9kxwkcbl	36	37	suppression	suppression	NN
cord-277648-9kxwkcbl	36	38	of	of	IN
cord-277648-9kxwkcbl	36	39	type	type	NN
cord-277648-9kxwkcbl	36	40	I	-PRON-	PRP
cord-277648-9kxwkcbl	36	41	and	and	CC
cord-277648-9kxwkcbl	36	42	type	type	NN
cord-277648-9kxwkcbl	36	43	II	II	NNP
cord-277648-9kxwkcbl	36	44	interferon	interferon	NN
cord-277648-9kxwkcbl	36	45	activity	activity	NN
cord-277648-9kxwkcbl	36	46	,	,	,
cord-277648-9kxwkcbl	36	47	and	and	CC
cord-277648-9kxwkcbl	36	48	decreased	decrease	VBD
cord-277648-9kxwkcbl	36	49	monocyte	monocyte	NNP
cord-277648-9kxwkcbl	36	50	HLA	HLA	NNP
cord-277648-9kxwkcbl	36	51	class	class	NN
cord-277648-9kxwkcbl	36	52	II	ii	CD
cord-277648-9kxwkcbl	36	53	expression	expression	NN
cord-277648-9kxwkcbl	36	54	[	[	-LRB-
cord-277648-9kxwkcbl	36	55	23	23	CD
cord-277648-9kxwkcbl	36	56	,	,	,
cord-277648-9kxwkcbl	36	57	24	24	CD
cord-277648-9kxwkcbl	36	58	,	,	,
cord-277648-9kxwkcbl	36	59	25	25	CD
cord-277648-9kxwkcbl	36	60	,	,	,
cord-277648-9kxwkcbl	36	61	26	26	CD
cord-277648-9kxwkcbl	36	62	]	]	-RRB-
cord-277648-9kxwkcbl	36	63	.	.	.
cord-277648-9kxwkcbl	37	1	Although	although	IN
cord-277648-9kxwkcbl	37	2	these	these	DT
cord-277648-9kxwkcbl	37	3	studies	study	NNS
cord-277648-9kxwkcbl	37	4	describe	describe	VBP
cord-277648-9kxwkcbl	37	5	immunological	immunological	JJ
cord-277648-9kxwkcbl	37	6	dysregulation	dysregulation	NN
cord-277648-9kxwkcbl	37	7	in	in	IN
cord-277648-9kxwkcbl	37	8	severe	severe	JJ
cord-277648-9kxwkcbl	37	9	COVID-19	covid-19	JJ
cord-277648-9kxwkcbl	37	10	patients	patient	NNS
cord-277648-9kxwkcbl	37	11	requiring	require	VBG
cord-277648-9kxwkcbl	37	12	intensive	intensive	JJ
cord-277648-9kxwkcbl	37	13	care	care	NN
cord-277648-9kxwkcbl	37	14	,	,	,
cord-277648-9kxwkcbl	37	15	they	-PRON-	PRP
cord-277648-9kxwkcbl	37	16	do	do	VBP
cord-277648-9kxwkcbl	37	17	not	not	RB
cord-277648-9kxwkcbl	37	18	explore	explore	VB
cord-277648-9kxwkcbl	37	19	immunological	immunological	JJ
cord-277648-9kxwkcbl	37	20	features	feature	NNS
cord-277648-9kxwkcbl	37	21	distinguishing	distinguish	VBG
cord-277648-9kxwkcbl	37	22	COVID-19	covid-19	CD
cord-277648-9kxwkcbl	37	23	patients	patient	NNS
cord-277648-9kxwkcbl	37	24	who	who	WP
cord-277648-9kxwkcbl	37	25	experience	experience	VBP
cord-277648-9kxwkcbl	37	26	moderate	moderate	JJ
cord-277648-9kxwkcbl	37	27	or	or	CC
cord-277648-9kxwkcbl	37	28	non	non	JJ
cord-277648-9kxwkcbl	37	29	-	-	JJ
cord-277648-9kxwkcbl	37	30	ARDS	ards	JJ
cord-277648-9kxwkcbl	37	31	pathology	pathology	NN
cord-277648-9kxwkcbl	37	32	from	from	IN
cord-277648-9kxwkcbl	37	33	those	those	DT
cord-277648-9kxwkcbl	37	34	who	who	WP
cord-277648-9kxwkcbl	37	35	progress	progress	VBP
cord-277648-9kxwkcbl	37	36	to	to	IN
cord-277648-9kxwkcbl	37	37	life	life	NN
cord-277648-9kxwkcbl	37	38	-	-	HYPH
cord-277648-9kxwkcbl	37	39	threatening	threaten	VBG
cord-277648-9kxwkcbl	37	40	disease	disease	NN
cord-277648-9kxwkcbl	37	41	courses	course	NNS
cord-277648-9kxwkcbl	37	42	.	.	.
cord-277648-9kxwkcbl	38	1	Single	single	JJ
cord-277648-9kxwkcbl	38	2	-	-	HYPH
cord-277648-9kxwkcbl	38	3	cell	cell	NN
cord-277648-9kxwkcbl	38	4	resolution	resolution	NN
cord-277648-9kxwkcbl	38	5	studies	study	NNS
cord-277648-9kxwkcbl	38	6	specifically	specifically	RB
cord-277648-9kxwkcbl	38	7	comparing	compare	VBG
cord-277648-9kxwkcbl	38	8	disease	disease	NN
cord-277648-9kxwkcbl	38	9	severity	severity	NN
cord-277648-9kxwkcbl	38	10	strata	stratum	NNS
cord-277648-9kxwkcbl	38	11	are	be	VBP
cord-277648-9kxwkcbl	38	12	needed	need	VBN
cord-277648-9kxwkcbl	38	13	to	to	TO
cord-277648-9kxwkcbl	38	14	reveal	reveal	VB
cord-277648-9kxwkcbl	38	15	the	the	DT
cord-277648-9kxwkcbl	38	16	immunological	immunological	JJ
cord-277648-9kxwkcbl	38	17	mechanisms	mechanism	NNS
cord-277648-9kxwkcbl	38	18	responsible	responsible	JJ
cord-277648-9kxwkcbl	38	19	for	for	IN
cord-277648-9kxwkcbl	38	20	severity	severity	NN
cord-277648-9kxwkcbl	38	21	-	-	HYPH
cord-277648-9kxwkcbl	38	22	specific	specific	JJ
cord-277648-9kxwkcbl	38	23	immune	immune	JJ
cord-277648-9kxwkcbl	38	24	dysregulation	dysregulation	NN
cord-277648-9kxwkcbl	38	25	and	and	CC
cord-277648-9kxwkcbl	38	26	to	to	TO
cord-277648-9kxwkcbl	38	27	identify	identify	VB
cord-277648-9kxwkcbl	38	28	signatures	signature	NNS
cord-277648-9kxwkcbl	38	29	of	of	IN
cord-277648-9kxwkcbl	38	30	disease	disease	NN
cord-277648-9kxwkcbl	38	31	severity	severity	NN
cord-277648-9kxwkcbl	38	32	that	that	WDT
cord-277648-9kxwkcbl	38	33	may	may	MD
cord-277648-9kxwkcbl	38	34	inform	inform	VB
cord-277648-9kxwkcbl	38	35	COVID-19	COVID-19	NNP
cord-277648-9kxwkcbl	38	36	patient	patient	JJ
cord-277648-9kxwkcbl	38	37	triage	triage	NN
cord-277648-9kxwkcbl	38	38	and	and	CC
cord-277648-9kxwkcbl	38	39	treatment	treatment	NN
cord-277648-9kxwkcbl	38	40	.	.	.
cord-277648-9kxwkcbl	39	1	While	while	IN
cord-277648-9kxwkcbl	39	2	many	many	JJ
cord-277648-9kxwkcbl	39	3	studies	study	NNS
cord-277648-9kxwkcbl	39	4	have	have	VBP
cord-277648-9kxwkcbl	39	5	endeavored	endeavor	VBN
cord-277648-9kxwkcbl	39	6	to	to	TO
cord-277648-9kxwkcbl	39	7	apply	apply	VB
cord-277648-9kxwkcbl	39	8	transcriptional	transcriptional	JJ
cord-277648-9kxwkcbl	39	9	profiling	profiling	NN
cord-277648-9kxwkcbl	39	10	to	to	TO
cord-277648-9kxwkcbl	39	11	understand	understand	VB
cord-277648-9kxwkcbl	39	12	the	the	DT
cord-277648-9kxwkcbl	39	13	cellular	cellular	JJ
cord-277648-9kxwkcbl	39	14	dynamics	dynamic	NNS
cord-277648-9kxwkcbl	39	15	underlying	underlie	VBG
cord-277648-9kxwkcbl	39	16	coronavirus	coronavirus	NN
cord-277648-9kxwkcbl	39	17	infection	infection	NN
cord-277648-9kxwkcbl	39	18	,	,	,
cord-277648-9kxwkcbl	39	19	to	to	IN
cord-277648-9kxwkcbl	39	20	our	-PRON-	PRP$
cord-277648-9kxwkcbl	39	21	knowledge	knowledge	NN
cord-277648-9kxwkcbl	39	22	,	,	,
cord-277648-9kxwkcbl	39	23	a	a	DT
cord-277648-9kxwkcbl	39	24	single	single	JJ
cord-277648-9kxwkcbl	39	25	integrative	integrative	JJ
cord-277648-9kxwkcbl	39	26	study	study	NN
cord-277648-9kxwkcbl	39	27	comparing	compare	VBG
cord-277648-9kxwkcbl	39	28	responses	response	NNS
cord-277648-9kxwkcbl	39	29	across	across	IN
cord-277648-9kxwkcbl	39	30	the	the	DT
cord-277648-9kxwkcbl	39	31	spectrum	spectrum	NN
cord-277648-9kxwkcbl	39	32	of	of	IN
cord-277648-9kxwkcbl	39	33	disease	disease	NN
cord-277648-9kxwkcbl	39	34	severity	severity	NN
cord-277648-9kxwkcbl	39	35	in	in	IN
cord-277648-9kxwkcbl	39	36	both	both	CC
cord-277648-9kxwkcbl	39	37	the	the	DT
cord-277648-9kxwkcbl	39	38	lung	lung	NN
cord-277648-9kxwkcbl	39	39	and	and	CC
cord-277648-9kxwkcbl	39	40	blood	blood	NN
cord-277648-9kxwkcbl	39	41	compartments	compartment	NNS
cord-277648-9kxwkcbl	39	42	has	have	VBZ
cord-277648-9kxwkcbl	39	43	not	not	RB
cord-277648-9kxwkcbl	39	44	yet	yet	RB
cord-277648-9kxwkcbl	39	45	been	be	VBN
cord-277648-9kxwkcbl	39	46	reported	report	VBN
cord-277648-9kxwkcbl	39	47	.	.	.
cord-277648-9kxwkcbl	40	1	Isolated	isolated	JJ
cord-277648-9kxwkcbl	40	2	analyses	analysis	NNS
cord-277648-9kxwkcbl	40	3	of	of	IN
cord-277648-9kxwkcbl	40	4	BALF	BALF	NNP
cord-277648-9kxwkcbl	40	5	samples	sample	NNS
cord-277648-9kxwkcbl	40	6	have	have	VBP
cord-277648-9kxwkcbl	40	7	shown	show	VBN
cord-277648-9kxwkcbl	40	8	neutrophil	neutrophil	NN
cord-277648-9kxwkcbl	40	9	and	and	CC
cord-277648-9kxwkcbl	40	10	proliferating	proliferate	VBG
cord-277648-9kxwkcbl	40	11	T	t	NN
cord-277648-9kxwkcbl	40	12	cell	cell	NN
cord-277648-9kxwkcbl	40	13	enrichment	enrichment	NN
cord-277648-9kxwkcbl	40	14	in	in	IN
cord-277648-9kxwkcbl	40	15	severe	severe	JJ
cord-277648-9kxwkcbl	40	16	over	over	IN
cord-277648-9kxwkcbl	40	17	moderate	moderate	JJ
cord-277648-9kxwkcbl	40	18	patients	patient	NNS
cord-277648-9kxwkcbl	40	19	accompanied	accompany	VBN
cord-277648-9kxwkcbl	40	20	by	by	IN
cord-277648-9kxwkcbl	40	21	CD8	CD8	NNP
cord-277648-9kxwkcbl	40	22	+	+	CC
cord-277648-9kxwkcbl	40	23	T	T	NNP
cord-277648-9kxwkcbl	40	24	cell	cell	NN
cord-277648-9kxwkcbl	40	25	lymphopenia	lymphopenia	NNP
cord-277648-9kxwkcbl	40	26	,	,	,
cord-277648-9kxwkcbl	40	27	a	a	DT
cord-277648-9kxwkcbl	40	28	shift	shift	NN
cord-277648-9kxwkcbl	40	29	towards	towards	IN
cord-277648-9kxwkcbl	40	30	inflammatory	inflammatory	JJ
cord-277648-9kxwkcbl	40	31	macrophage	macrophage	NN
cord-277648-9kxwkcbl	40	32	polarization	polarization	NN
cord-277648-9kxwkcbl	40	33	,	,	,
cord-277648-9kxwkcbl	40	34	and	and	CC
cord-277648-9kxwkcbl	40	35	increased	increase	VBN
cord-277648-9kxwkcbl	40	36	transcriptional	transcriptional	JJ
cord-277648-9kxwkcbl	40	37	expression	expression	NN
cord-277648-9kxwkcbl	40	38	of	of	IN
cord-277648-9kxwkcbl	40	39	a	a	DT
cord-277648-9kxwkcbl	40	40	variety	variety	NN
cord-277648-9kxwkcbl	40	41	of	of	IN
cord-277648-9kxwkcbl	40	42	cytokines	cytokine	NNS
cord-277648-9kxwkcbl	40	43	[	[	-LRB-
cord-277648-9kxwkcbl	40	44	27	27	CD
cord-277648-9kxwkcbl	40	45	,	,	,
cord-277648-9kxwkcbl	40	46	28	28	CD
cord-277648-9kxwkcbl	40	47	]	]	-RRB-
cord-277648-9kxwkcbl	40	48	.	.	.
cord-277648-9kxwkcbl	41	1	Previous	previous	JJ
cord-277648-9kxwkcbl	41	2	investigations	investigation	NNS
cord-277648-9kxwkcbl	41	3	focusing	focus	VBG
cord-277648-9kxwkcbl	41	4	only	only	RB
cord-277648-9kxwkcbl	41	5	on	on	IN
cord-277648-9kxwkcbl	41	6	peripheral	peripheral	JJ
cord-277648-9kxwkcbl	41	7	blood	blood	NN
cord-277648-9kxwkcbl	41	8	responses	response	NNS
cord-277648-9kxwkcbl	41	9	have	have	VBP
cord-277648-9kxwkcbl	41	10	shown	show	VBN
cord-277648-9kxwkcbl	41	11	various	various	JJ
cord-277648-9kxwkcbl	41	12	compositional	compositional	JJ
cord-277648-9kxwkcbl	41	13	shifts	shift	NNS
cord-277648-9kxwkcbl	41	14	between	between	IN
cord-277648-9kxwkcbl	41	15	severe	severe	JJ
cord-277648-9kxwkcbl	41	16	and	and	CC
cord-277648-9kxwkcbl	41	17	moderate	moderate	JJ
cord-277648-9kxwkcbl	41	18	disease	disease	NN
cord-277648-9kxwkcbl	41	19	including	include	VBG
cord-277648-9kxwkcbl	41	20	cytopenias	cytopenia	NNS
cord-277648-9kxwkcbl	41	21	of	of	IN
cord-277648-9kxwkcbl	41	22	monocytes	monocyte	NNS
cord-277648-9kxwkcbl	41	23	,	,	,
cord-277648-9kxwkcbl	41	24	natural	natural	JJ
cord-277648-9kxwkcbl	41	25	killer	killer	NN
cord-277648-9kxwkcbl	41	26	(	(	-LRB-
cord-277648-9kxwkcbl	41	27	NK	NK	NNP
cord-277648-9kxwkcbl	41	28	)	)	-RRB-
cord-277648-9kxwkcbl	41	29	cells	cell	NNS
cord-277648-9kxwkcbl	41	30	,	,	,
cord-277648-9kxwkcbl	41	31	dendritic	dendritic	JJ
cord-277648-9kxwkcbl	41	32	cells	cell	NNS
cord-277648-9kxwkcbl	41	33	(	(	-LRB-
cord-277648-9kxwkcbl	41	34	DCs	DCs	NNP
cord-277648-9kxwkcbl	41	35	)	)	-RRB-
cord-277648-9kxwkcbl	41	36	,	,	,
cord-277648-9kxwkcbl	41	37	and	and	CC
cord-277648-9kxwkcbl	41	38	T	t	NN
cord-277648-9kxwkcbl	41	39	cells	cell	NNS
cord-277648-9kxwkcbl	41	40	,	,	,
cord-277648-9kxwkcbl	41	41	[	[	-LRB-
cord-277648-9kxwkcbl	41	42	28	28	CD
cord-277648-9kxwkcbl	41	43	,	,	,
cord-277648-9kxwkcbl	41	44	29	29	CD
cord-277648-9kxwkcbl	41	45	,	,	,
cord-277648-9kxwkcbl	41	46	30	30	CD
cord-277648-9kxwkcbl	41	47	,	,	,
cord-277648-9kxwkcbl	41	48	31	31	CD
cord-277648-9kxwkcbl	41	49	,	,	,
cord-277648-9kxwkcbl	41	50	32	32	CD
cord-277648-9kxwkcbl	41	51	]	]	-RRB-
cord-277648-9kxwkcbl	41	52	accompanied	accompany	VBN
cord-277648-9kxwkcbl	41	53	by	by	IN
cord-277648-9kxwkcbl	41	54	increases	increase	NNS
cord-277648-9kxwkcbl	41	55	in	in	IN
cord-277648-9kxwkcbl	41	56	plasmablasts	plasmablast	NNS
cord-277648-9kxwkcbl	41	57	,	,	,
cord-277648-9kxwkcbl	41	58	B	b	NN
cord-277648-9kxwkcbl	41	59	cells	cell	NNS
cord-277648-9kxwkcbl	41	60	,	,	,
cord-277648-9kxwkcbl	41	61	and	and	CC
cord-277648-9kxwkcbl	41	62	neutrophils	neutrophil	NNS
cord-277648-9kxwkcbl	41	63	[	[	-LRB-
cord-277648-9kxwkcbl	41	64	33	33	CD
cord-277648-9kxwkcbl	41	65	,	,	,
cord-277648-9kxwkcbl	41	66	34	34	CD
cord-277648-9kxwkcbl	41	67	,	,	,
cord-277648-9kxwkcbl	41	68	35	35	CD
cord-277648-9kxwkcbl	41	69	,	,	,
cord-277648-9kxwkcbl	41	70	36	36	CD
cord-277648-9kxwkcbl	41	71	]	]	-RRB-
cord-277648-9kxwkcbl	41	72	.	.	.
cord-277648-9kxwkcbl	42	1	Serum	serum	NN
cord-277648-9kxwkcbl	42	2	cytokine	cytokine	NN
cord-277648-9kxwkcbl	42	3	levels	level	NNS
cord-277648-9kxwkcbl	42	4	are	be	VBP
cord-277648-9kxwkcbl	42	5	reportedly	reportedly	RB
cord-277648-9kxwkcbl	42	6	altered	alter	VBN
cord-277648-9kxwkcbl	42	7	between	between	IN
cord-277648-9kxwkcbl	42	8	severe	severe	JJ
cord-277648-9kxwkcbl	42	9	and	and	CC
cord-277648-9kxwkcbl	42	10	moderate	moderate	JJ
cord-277648-9kxwkcbl	42	11	patients	patient	NNS
cord-277648-9kxwkcbl	42	12	,	,	,
cord-277648-9kxwkcbl	42	13	including	include	VBG
cord-277648-9kxwkcbl	42	14	increased	increase	VBN
cord-277648-9kxwkcbl	42	15	IL-6	IL-6	NNP
cord-277648-9kxwkcbl	42	16	,	,	,
cord-277648-9kxwkcbl	42	17	IL-8	IL-8	NNP
cord-277648-9kxwkcbl	42	18	,	,	,
cord-277648-9kxwkcbl	42	19	and	and	CC
cord-277648-9kxwkcbl	42	20	TNF	TNF	NNP
cord-277648-9kxwkcbl	42	21	-	-	HYPH
cord-277648-9kxwkcbl	42	22	ɑ	ɑ	NNP
cord-277648-9kxwkcbl	42	23	[	[	-LRB-
cord-277648-9kxwkcbl	42	24	11	11	CD
cord-277648-9kxwkcbl	42	25	,	,	,
cord-277648-9kxwkcbl	42	26	35	35	CD
cord-277648-9kxwkcbl	42	27	]	]	-RRB-
cord-277648-9kxwkcbl	42	28	and	and	CC
cord-277648-9kxwkcbl	42	29	deficient	deficient	JJ
cord-277648-9kxwkcbl	42	30	IFN	IFN	NNP
cord-277648-9kxwkcbl	42	31	-	-	HYPH
cord-277648-9kxwkcbl	42	32	α	α	NNP
cord-277648-9kxwkcbl	42	33	and	and	CC
cord-277648-9kxwkcbl	42	34	IFN	IFN	NNP
cord-277648-9kxwkcbl	42	35	-	-	HYPH
cord-277648-9kxwkcbl	42	36	γ	γ	NNP
cord-277648-9kxwkcbl	42	37	[	[	-LRB-
cord-277648-9kxwkcbl	42	38	33	33	CD
cord-277648-9kxwkcbl	42	39	]	]	-RRB-
cord-277648-9kxwkcbl	42	40	,	,	,
cord-277648-9kxwkcbl	42	41	while	while	IN
cord-277648-9kxwkcbl	42	42	blood	blood	NN
cord-277648-9kxwkcbl	42	43	single	single	JJ
cord-277648-9kxwkcbl	42	44	-	-	HYPH
cord-277648-9kxwkcbl	42	45	cell	cell	NN
cord-277648-9kxwkcbl	42	46	transcriptional	transcriptional	JJ
cord-277648-9kxwkcbl	42	47	analyses	analysis	NNS
cord-277648-9kxwkcbl	42	48	have	have	VBP
cord-277648-9kxwkcbl	42	49	shown	show	VBN
cord-277648-9kxwkcbl	42	50	alteration	alteration	NN
cord-277648-9kxwkcbl	42	51	of	of	IN
cord-277648-9kxwkcbl	42	52	the	the	DT
cord-277648-9kxwkcbl	42	53	TNF	TNF	NNP
cord-277648-9kxwkcbl	42	54	-	-	HYPH
cord-277648-9kxwkcbl	42	55	α	α	NNP
cord-277648-9kxwkcbl	42	56	/	/	SYM
cord-277648-9kxwkcbl	42	57	NF	nf	NN
cord-277648-9kxwkcbl	42	58	-	-	HYPH
cord-277648-9kxwkcbl	42	59	κB	κB	NNP
cord-277648-9kxwkcbl	42	60	pathway	pathway	NN
cord-277648-9kxwkcbl	42	61	,	,	,
cord-277648-9kxwkcbl	42	62	interferon	interferon	NN
cord-277648-9kxwkcbl	42	63	signatures	signature	NNS
cord-277648-9kxwkcbl	42	64	,	,	,
cord-277648-9kxwkcbl	42	65	and	and	CC
cord-277648-9kxwkcbl	42	66	HLA	HLA	NNP
cord-277648-9kxwkcbl	42	67	class	class	NN
cord-277648-9kxwkcbl	42	68	II	ii	CD
cord-277648-9kxwkcbl	42	69	expression	expression	NN
cord-277648-9kxwkcbl	42	70	[	[	-LRB-
cord-277648-9kxwkcbl	42	71	33	33	CD
cord-277648-9kxwkcbl	42	72	,	,	,
cord-277648-9kxwkcbl	42	73	34	34	CD
cord-277648-9kxwkcbl	42	74	,	,	,
cord-277648-9kxwkcbl	42	75	36	36	CD
cord-277648-9kxwkcbl	42	76	,	,	,
cord-277648-9kxwkcbl	42	77	32	32	CD
cord-277648-9kxwkcbl	42	78	]	]	-RRB-
cord-277648-9kxwkcbl	42	79	.	.	.
cord-277648-9kxwkcbl	43	1	While	while	IN
cord-277648-9kxwkcbl	43	2	individual	individual	JJ
cord-277648-9kxwkcbl	43	3	studies	study	NNS
cord-277648-9kxwkcbl	43	4	have	have	VBP
cord-277648-9kxwkcbl	43	5	increased	increase	VBN
cord-277648-9kxwkcbl	43	6	our	-PRON-	PRP$
cord-277648-9kxwkcbl	43	7	understanding	understanding	NN
cord-277648-9kxwkcbl	43	8	of	of	IN
cord-277648-9kxwkcbl	43	9	severe	severe	JJ
cord-277648-9kxwkcbl	43	10	COVID-19	covid-19	NN
cord-277648-9kxwkcbl	43	11	in	in	IN
cord-277648-9kxwkcbl	43	12	the	the	DT
cord-277648-9kxwkcbl	43	13	lung	lung	NN
cord-277648-9kxwkcbl	43	14	and	and	CC
cord-277648-9kxwkcbl	43	15	blood	blood	NN
cord-277648-9kxwkcbl	43	16	separately	separately	RB
cord-277648-9kxwkcbl	43	17	,	,	,
cord-277648-9kxwkcbl	43	18	transcriptional	transcriptional	JJ
cord-277648-9kxwkcbl	43	19	dynamics	dynamic	NNS
cord-277648-9kxwkcbl	43	20	have	have	VBP
cord-277648-9kxwkcbl	43	21	not	not	RB
cord-277648-9kxwkcbl	43	22	been	be	VBN
cord-277648-9kxwkcbl	43	23	leveraged	leverage	VBN
cord-277648-9kxwkcbl	43	24	to	to	TO
cord-277648-9kxwkcbl	43	25	propose	propose	VB
cord-277648-9kxwkcbl	43	26	detectable	detectable	JJ
cord-277648-9kxwkcbl	43	27	cell	cell	NN
cord-277648-9kxwkcbl	43	28	surface	surface	NN
cord-277648-9kxwkcbl	43	29	markers	marker	NNS
cord-277648-9kxwkcbl	43	30	correlated	correlate	VBN
cord-277648-9kxwkcbl	43	31	with	with	IN
cord-277648-9kxwkcbl	43	32	the	the	DT
cord-277648-9kxwkcbl	43	33	level	level	NN
cord-277648-9kxwkcbl	43	34	of	of	IN
cord-277648-9kxwkcbl	43	35	a	a	DT
cord-277648-9kxwkcbl	43	36	patient	patient	NN
cord-277648-9kxwkcbl	43	37	's	's	POS
cord-277648-9kxwkcbl	43	38	disease	disease	NN
cord-277648-9kxwkcbl	43	39	severity	severity	NN
cord-277648-9kxwkcbl	43	40	in	in	IN
cord-277648-9kxwkcbl	43	41	cell	cell	NN
cord-277648-9kxwkcbl	43	42	types	type	NNS
cord-277648-9kxwkcbl	43	43	of	of	IN
cord-277648-9kxwkcbl	43	44	either	either	DT
cord-277648-9kxwkcbl	43	45	compartment	compartment	NN
cord-277648-9kxwkcbl	43	46	.	.	.
cord-277648-9kxwkcbl	44	1	Another	another	DT
cord-277648-9kxwkcbl	44	2	large	large	JJ
cord-277648-9kxwkcbl	44	3	gap	gap	NN
cord-277648-9kxwkcbl	44	4	in	in	IN
cord-277648-9kxwkcbl	44	5	the	the	DT
cord-277648-9kxwkcbl	44	6	literature	literature	NN
cord-277648-9kxwkcbl	44	7	persists	persist	VBZ
cord-277648-9kxwkcbl	44	8	regarding	regard	VBG
cord-277648-9kxwkcbl	44	9	the	the	DT
cord-277648-9kxwkcbl	44	10	transcriptional	transcriptional	JJ
cord-277648-9kxwkcbl	44	11	similarities	similarity	NNS
cord-277648-9kxwkcbl	44	12	and	and	CC
cord-277648-9kxwkcbl	44	13	differences	difference	NNS
cord-277648-9kxwkcbl	44	14	between	between	IN
cord-277648-9kxwkcbl	44	15	the	the	DT
cord-277648-9kxwkcbl	44	16	local	local	JJ
cord-277648-9kxwkcbl	44	17	and	and	CC
cord-277648-9kxwkcbl	44	18	peripheral	peripheral	JJ
cord-277648-9kxwkcbl	44	19	immune	immune	JJ
cord-277648-9kxwkcbl	44	20	environments	environment	NNS
cord-277648-9kxwkcbl	44	21	.	.	.
cord-277648-9kxwkcbl	45	1	Critically	critically	RB
cord-277648-9kxwkcbl	45	2	,	,	,
cord-277648-9kxwkcbl	45	3	dysregulated	dysregulate	VBN
cord-277648-9kxwkcbl	45	4	biological	biological	JJ
cord-277648-9kxwkcbl	45	5	pathways	pathway	NNS
cord-277648-9kxwkcbl	45	6	and	and	CC
cord-277648-9kxwkcbl	45	7	their	-PRON-	PRP$
cord-277648-9kxwkcbl	45	8	correlation	correlation	NN
cord-277648-9kxwkcbl	45	9	with	with	IN
cord-277648-9kxwkcbl	45	10	clinical	clinical	JJ
cord-277648-9kxwkcbl	45	11	severity	severity	NN
cord-277648-9kxwkcbl	45	12	levels	level	NNS
cord-277648-9kxwkcbl	45	13	remain	remain	VBP
cord-277648-9kxwkcbl	45	14	poorly	poorly	RB
cord-277648-9kxwkcbl	45	15	understood	understand	VBN
cord-277648-9kxwkcbl	45	16	in	in	IN
cord-277648-9kxwkcbl	45	17	immune	immune	JJ
cord-277648-9kxwkcbl	45	18	cells	cell	NNS
cord-277648-9kxwkcbl	45	19	of	of	IN
cord-277648-9kxwkcbl	45	20	both	both	DT
cord-277648-9kxwkcbl	45	21	compartments	compartment	NNS
cord-277648-9kxwkcbl	45	22	.	.	.
cord-277648-9kxwkcbl	46	1	Immuneepithelial	Immuneepithelial	NNP
cord-277648-9kxwkcbl	46	2	signaling	signal	VBG
cord-277648-9kxwkcbl	46	3	dynamics	dynamic	NNS
cord-277648-9kxwkcbl	46	4	at	at	IN
cord-277648-9kxwkcbl	46	5	the	the	DT
cord-277648-9kxwkcbl	46	6	site	site	NN
cord-277648-9kxwkcbl	46	7	of	of	IN
cord-277648-9kxwkcbl	46	8	local	local	JJ
cord-277648-9kxwkcbl	46	9	infection	infection	NN
cord-277648-9kxwkcbl	46	10	likely	likely	RB
cord-277648-9kxwkcbl	46	11	play	play	VBP
cord-277648-9kxwkcbl	46	12	a	a	DT
cord-277648-9kxwkcbl	46	13	supporting	support	VBG
cord-277648-9kxwkcbl	46	14	role	role	NN
cord-277648-9kxwkcbl	46	15	in	in	IN
cord-277648-9kxwkcbl	46	16	severe	severe	JJ
cord-277648-9kxwkcbl	46	17	responses	response	NNS
cord-277648-9kxwkcbl	46	18	but	but	CC
cord-277648-9kxwkcbl	46	19	have	have	VBP
cord-277648-9kxwkcbl	46	20	also	also	RB
cord-277648-9kxwkcbl	46	21	not	not	RB
cord-277648-9kxwkcbl	46	22	been	be	VBN
cord-277648-9kxwkcbl	46	23	rigorously	rigorously	RB
cord-277648-9kxwkcbl	46	24	described	describe	VBN
cord-277648-9kxwkcbl	46	25	.	.	.
cord-277648-9kxwkcbl	47	1	An	an	DT
cord-277648-9kxwkcbl	47	2	overarching	overarching	JJ
cord-277648-9kxwkcbl	47	3	unaddressed	unaddressed	JJ
cord-277648-9kxwkcbl	47	4	question	question	NN
cord-277648-9kxwkcbl	47	5	is	be	VBZ
cord-277648-9kxwkcbl	47	6	the	the	DT
cord-277648-9kxwkcbl	47	7	possibility	possibility	NN
cord-277648-9kxwkcbl	47	8	for	for	IN
cord-277648-9kxwkcbl	47	9	therapeutic	therapeutic	JJ
cord-277648-9kxwkcbl	47	10	interventions	intervention	NNS
cord-277648-9kxwkcbl	47	11	to	to	TO
cord-277648-9kxwkcbl	47	12	affect	affect	VB
cord-277648-9kxwkcbl	47	13	the	the	DT
cord-277648-9kxwkcbl	47	14	lung	lung	NN
cord-277648-9kxwkcbl	47	15	and	and	CC
cord-277648-9kxwkcbl	47	16	blood	blood	NN
cord-277648-9kxwkcbl	47	17	compartments	compartment	NNS
cord-277648-9kxwkcbl	47	18	differently	differently	RB
cord-277648-9kxwkcbl	47	19	;	;	:
cord-277648-9kxwkcbl	47	20	thus	thus	RB
cord-277648-9kxwkcbl	47	21	,	,	,
cord-277648-9kxwkcbl	47	22	generating	generate	VBG
cord-277648-9kxwkcbl	47	23	comparative	comparative	JJ
cord-277648-9kxwkcbl	47	24	transcriptional	transcriptional	JJ
cord-277648-9kxwkcbl	47	25	data	datum	NNS
cord-277648-9kxwkcbl	47	26	will	will	MD
cord-277648-9kxwkcbl	47	27	be	be	VB
cord-277648-9kxwkcbl	47	28	useful	useful	JJ
cord-277648-9kxwkcbl	47	29	for	for	IN
cord-277648-9kxwkcbl	47	30	determining	determine	VBG
cord-277648-9kxwkcbl	47	31	efficacious	efficacious	JJ
cord-277648-9kxwkcbl	47	32	treatment	treatment	NN
cord-277648-9kxwkcbl	47	33	strategies	strategy	NNS
cord-277648-9kxwkcbl	47	34	for	for	IN
cord-277648-9kxwkcbl	47	35	severe	severe	JJ
cord-277648-9kxwkcbl	48	1	In	in	IN
cord-277648-9kxwkcbl	48	2	this	this	DT
cord-277648-9kxwkcbl	48	3	study	study	NN
cord-277648-9kxwkcbl	48	4	,	,	,
cord-277648-9kxwkcbl	48	5	we	-PRON-	PRP
cord-277648-9kxwkcbl	48	6	present	present	VBP
cord-277648-9kxwkcbl	48	7	comparisons	comparison	NNS
cord-277648-9kxwkcbl	48	8	between	between	IN
cord-277648-9kxwkcbl	48	9	immunological	immunological	JJ
cord-277648-9kxwkcbl	48	10	signatures	signature	NNS
cord-277648-9kxwkcbl	48	11	of	of	IN
cord-277648-9kxwkcbl	48	12	COVID-19	covid-19	NN
cord-277648-9kxwkcbl	48	13	based	base	VBN
cord-277648-9kxwkcbl	48	14	on	on	IN
cord-277648-9kxwkcbl	48	15	clinical	clinical	JJ
cord-277648-9kxwkcbl	48	16	severity	severity	NN
cord-277648-9kxwkcbl	48	17	level	level	NN
cord-277648-9kxwkcbl	48	18	in	in	IN
cord-277648-9kxwkcbl	48	19	both	both	CC
cord-277648-9kxwkcbl	48	20	the	the	DT
cord-277648-9kxwkcbl	48	21	lung	lung	NN
cord-277648-9kxwkcbl	48	22	and	and	CC
cord-277648-9kxwkcbl	48	23	blood	blood	NN
cord-277648-9kxwkcbl	48	24	compartments	compartment	NNS
cord-277648-9kxwkcbl	48	25	using	use	VBG
cord-277648-9kxwkcbl	48	26	identical	identical	JJ
cord-277648-9kxwkcbl	48	27	methods	method	NNS
cord-277648-9kxwkcbl	48	28	.	.	.
cord-277648-9kxwkcbl	49	1	We	-PRON-	PRP
cord-277648-9kxwkcbl	49	2	re	re	VBD
cord-277648-9kxwkcbl	49	3	-	-	VBD
cord-277648-9kxwkcbl	49	4	analyzed	analyze	VBD
cord-277648-9kxwkcbl	49	5	two	two	CD
cord-277648-9kxwkcbl	49	6	publicly	publicly	RB
cord-277648-9kxwkcbl	49	7	available	available	JJ
cord-277648-9kxwkcbl	49	8	scRNA	scrna	NN
cord-277648-9kxwkcbl	49	9	-	-	HYPH
cord-277648-9kxwkcbl	49	10	seq	seq	NN
cord-277648-9kxwkcbl	49	11	datasets	dataset	NNS
cord-277648-9kxwkcbl	49	12	:	:	:
cord-277648-9kxwkcbl	49	13	one	one	CD
cord-277648-9kxwkcbl	49	14	containing	contain	VBG
cord-277648-9kxwkcbl	49	15	BALF	BALF	NNP
cord-277648-9kxwkcbl	49	16	cells	cell	NNS
cord-277648-9kxwkcbl	49	17	from	from	IN
cord-277648-9kxwkcbl	49	18	donors	donor	NNS
cord-277648-9kxwkcbl	49	19	stratified	stratify	VBN
cord-277648-9kxwkcbl	49	20	by	by	IN
cord-277648-9kxwkcbl	49	21	the	the	DT
cord-277648-9kxwkcbl	49	22	original	original	JJ
cord-277648-9kxwkcbl	49	23	authors	author	NNS
cord-277648-9kxwkcbl	49	24	as	as	IN
cord-277648-9kxwkcbl	49	25	"	"	``
cord-277648-9kxwkcbl	49	26	moderate	moderate	JJ
cord-277648-9kxwkcbl	49	27	"	"	''
cord-277648-9kxwkcbl	49	28	and	and	CC
cord-277648-9kxwkcbl	49	29	"	"	``
cord-277648-9kxwkcbl	49	30	severe	severe	JJ
cord-277648-9kxwkcbl	49	31	"	"	''
cord-277648-9kxwkcbl	49	32	COVID-19	covid-19	JJ
cord-277648-9kxwkcbl	49	33	patients	patient	NNS
cord-277648-9kxwkcbl	49	34	as	as	RB
cord-277648-9kxwkcbl	49	35	well	well	RB
cord-277648-9kxwkcbl	49	36	as	as	IN
cord-277648-9kxwkcbl	49	37	healthy	healthy	JJ
cord-277648-9kxwkcbl	49	38	control	control	NN
cord-277648-9kxwkcbl	49	39	subjects	subject	NNS
cord-277648-9kxwkcbl	49	40	,	,	,
cord-277648-9kxwkcbl	49	41	obtained	obtain	VBN
cord-277648-9kxwkcbl	49	42	from	from	IN
cord-277648-9kxwkcbl	49	43	Liao	Liao	NNP
cord-277648-9kxwkcbl	49	44	et	et	FW
cord-277648-9kxwkcbl	49	45	al	al	NNP
cord-277648-9kxwkcbl	49	46	.	.	.
cord-277648-9kxwkcbl	50	1	[	[	-LRB-
cord-277648-9kxwkcbl	50	2	27	27	CD
cord-277648-9kxwkcbl	50	3	]	]	-RRB-
cord-277648-9kxwkcbl	50	4	,	,	,
cord-277648-9kxwkcbl	50	5	and	and	CC
cord-277648-9kxwkcbl	50	6	one	one	CD
cord-277648-9kxwkcbl	50	7	containing	contain	VBG
cord-277648-9kxwkcbl	50	8	PBMCs	pbmc	NNS
cord-277648-9kxwkcbl	50	9	from	from	IN
cord-277648-9kxwkcbl	50	10	donors	donor	NNS
cord-277648-9kxwkcbl	50	11	stratified	stratify	VBN
cord-277648-9kxwkcbl	50	12	by	by	IN
cord-277648-9kxwkcbl	50	13	the	the	DT
cord-277648-9kxwkcbl	50	14	original	original	JJ
cord-277648-9kxwkcbl	50	15	authors	author	NNS
cord-277648-9kxwkcbl	50	16	as	as	IN
cord-277648-9kxwkcbl	50	17	"	"	``
cord-277648-9kxwkcbl	50	18	non	non	JJ
cord-277648-9kxwkcbl	50	19	-	-	JJ
cord-277648-9kxwkcbl	50	20	ARDS	ARDS	NNP
cord-277648-9kxwkcbl	50	21	"	"	''
cord-277648-9kxwkcbl	50	22	and	and	CC
cord-277648-9kxwkcbl	50	23	"	"	``
cord-277648-9kxwkcbl	50	24	ARDS	ARDS	NNP
cord-277648-9kxwkcbl	50	25	"	"	''
cord-277648-9kxwkcbl	50	26	patients	patient	NNS
cord-277648-9kxwkcbl	50	27	as	as	RB
cord-277648-9kxwkcbl	50	28	well	well	RB
cord-277648-9kxwkcbl	50	29	as	as	IN
cord-277648-9kxwkcbl	50	30	healthy	healthy	JJ
cord-277648-9kxwkcbl	50	31	control	control	NN
cord-277648-9kxwkcbl	50	32	subjects	subject	NNS
cord-277648-9kxwkcbl	50	33	,	,	,
cord-277648-9kxwkcbl	50	34	obtained	obtain	VBN
cord-277648-9kxwkcbl	50	35	from	from	IN
cord-277648-9kxwkcbl	50	36	Wilk	Wilk	NNP
cord-277648-9kxwkcbl	50	37	et	et	NNP
cord-277648-9kxwkcbl	50	38	al	al	NNP
cord-277648-9kxwkcbl	50	39	.	.	.
cord-277648-9kxwkcbl	51	1	[	[	-LRB-
cord-277648-9kxwkcbl	51	2	32	32	CD
cord-277648-9kxwkcbl	51	3	]	]	-RRB-
cord-277648-9kxwkcbl	52	1	For	for	IN
cord-277648-9kxwkcbl	52	2	both	both	DT
cord-277648-9kxwkcbl	52	3	of	of	IN
cord-277648-9kxwkcbl	52	4	these	these	DT
cord-277648-9kxwkcbl	52	5	datasets	dataset	NNS
cord-277648-9kxwkcbl	52	6	we	-PRON-	PRP
cord-277648-9kxwkcbl	52	7	conducted	conduct	VBD
cord-277648-9kxwkcbl	52	8	identical	identical	JJ
cord-277648-9kxwkcbl	52	9	pre	pre	JJ
cord-277648-9kxwkcbl	52	10	-	-	JJ
cord-277648-9kxwkcbl	52	11	processing	processing	JJ
cord-277648-9kxwkcbl	52	12	,	,	,
cord-277648-9kxwkcbl	52	13	integration	integration	NN
cord-277648-9kxwkcbl	52	14	and	and	CC
cord-277648-9kxwkcbl	52	15	analysis	analysis	NN
cord-277648-9kxwkcbl	52	16	in	in	IN
cord-277648-9kxwkcbl	52	17	order	order	NN
cord-277648-9kxwkcbl	52	18	to	to	TO
cord-277648-9kxwkcbl	52	19	obtain	obtain	VB
cord-277648-9kxwkcbl	52	20	comparable	comparable	JJ
cord-277648-9kxwkcbl	52	21	results	result	NNS
cord-277648-9kxwkcbl	52	22	.	.	.
cord-277648-9kxwkcbl	53	1	We	-PRON-	PRP
cord-277648-9kxwkcbl	53	2	first	first	RB
cord-277648-9kxwkcbl	53	3	evaluated	evaluate	VBD
cord-277648-9kxwkcbl	53	4	differential	differential	JJ
cord-277648-9kxwkcbl	53	5	gene	gene	NN
cord-277648-9kxwkcbl	53	6	expression	expression	NN
cord-277648-9kxwkcbl	53	7	and	and	CC
cord-277648-9kxwkcbl	53	8	pathway	pathway	NN
cord-277648-9kxwkcbl	53	9	-	-	HYPH
cord-277648-9kxwkcbl	53	10	level	level	NN
cord-277648-9kxwkcbl	53	11	changes	change	NNS
cord-277648-9kxwkcbl	53	12	across	across	IN
cord-277648-9kxwkcbl	53	13	the	the	DT
cord-277648-9kxwkcbl	53	14	disease	disease	NN
cord-277648-9kxwkcbl	53	15	severity	severity	NN
cord-277648-9kxwkcbl	53	16	stratifications	stratification	NNS
cord-277648-9kxwkcbl	53	17	mentioned	mention	VBN
cord-277648-9kxwkcbl	53	18	above	above	RB
cord-277648-9kxwkcbl	53	19	for	for	IN
cord-277648-9kxwkcbl	53	20	each	each	DT
cord-277648-9kxwkcbl	53	21	cell	cell	NN
cord-277648-9kxwkcbl	53	22	type	type	NN
cord-277648-9kxwkcbl	53	23	in	in	IN
cord-277648-9kxwkcbl	53	24	the	the	DT
cord-277648-9kxwkcbl	53	25	BALF	BALF	NNP
cord-277648-9kxwkcbl	53	26	and	and	CC
cord-277648-9kxwkcbl	53	27	the	the	DT
cord-277648-9kxwkcbl	53	28	PBMC	PBMC	NNP
cord-277648-9kxwkcbl	53	29	datasets	dataset	NNS
cord-277648-9kxwkcbl	53	30	.	.	.
cord-277648-9kxwkcbl	54	1	Next	next	RB
cord-277648-9kxwkcbl	54	2	,	,	,
cord-277648-9kxwkcbl	54	3	we	-PRON-	PRP
cord-277648-9kxwkcbl	54	4	leveraged	leverage	VBD
cord-277648-9kxwkcbl	54	5	differential	differential	JJ
cord-277648-9kxwkcbl	54	6	expression	expression	NN
cord-277648-9kxwkcbl	54	7	data	datum	NNS
cord-277648-9kxwkcbl	54	8	to	to	TO
cord-277648-9kxwkcbl	54	9	identify	identify	VB
cord-277648-9kxwkcbl	54	10	cell	cell	NN
cord-277648-9kxwkcbl	54	11	surface	surface	NN
cord-277648-9kxwkcbl	54	12	proteins	protein	NNS
cord-277648-9kxwkcbl	54	13	that	that	WDT
cord-277648-9kxwkcbl	54	14	could	could	MD
cord-277648-9kxwkcbl	54	15	be	be	VB
cord-277648-9kxwkcbl	54	16	promising	promising	JJ
cord-277648-9kxwkcbl	54	17	markers	marker	NNS
cord-277648-9kxwkcbl	54	18	for	for	IN
cord-277648-9kxwkcbl	54	19	COVID-19	covid-19	JJ
cord-277648-9kxwkcbl	54	20	severity	severity	NN
cord-277648-9kxwkcbl	54	21	immunophenotyping	immunophenotyping	NN
cord-277648-9kxwkcbl	54	22	.	.	.
cord-277648-9kxwkcbl	55	1	Finally	finally	RB
cord-277648-9kxwkcbl	55	2	,	,	,
cord-277648-9kxwkcbl	55	3	we	-PRON-	PRP
cord-277648-9kxwkcbl	55	4	investigated	investigate	VBD
cord-277648-9kxwkcbl	55	5	ligand	ligand	NN
cord-277648-9kxwkcbl	55	6	-	-	HYPH
cord-277648-9kxwkcbl	55	7	receptor	receptor	NN
cord-277648-9kxwkcbl	55	8	interactions	interaction	NNS
cord-277648-9kxwkcbl	55	9	implicated	implicate	VBN
cord-277648-9kxwkcbl	55	10	in	in	IN
cord-277648-9kxwkcbl	55	11	regulating	regulate	VBG
cord-277648-9kxwkcbl	55	12	severity	severity	NN
cord-277648-9kxwkcbl	55	13	-	-	HYPH
cord-277648-9kxwkcbl	55	14	specific	specific	JJ
cord-277648-9kxwkcbl	55	15	immunophenotypes	immunophenotype	NNS
cord-277648-9kxwkcbl	55	16	using	use	VBG
cord-277648-9kxwkcbl	55	17	NicheNet	NicheNet	NNP
cord-277648-9kxwkcbl	55	18	network	network	NN
cord-277648-9kxwkcbl	55	19	analysis	analysis	NN
cord-277648-9kxwkcbl	55	20	[	[	-LRB-
cord-277648-9kxwkcbl	55	21	37	37	CD
cord-277648-9kxwkcbl	55	22	]	]	-RRB-
cord-277648-9kxwkcbl	55	23	and	and	CC
cord-277648-9kxwkcbl	55	24	we	-PRON-	PRP
cord-277648-9kxwkcbl	55	25	propose	propose	VBP
cord-277648-9kxwkcbl	55	26	multiple	multiple	JJ
cord-277648-9kxwkcbl	55	27	'	'	``
cord-277648-9kxwkcbl	55	28	pan	pan	JJ
cord-277648-9kxwkcbl	55	29	-	-	HYPH
cord-277648-9kxwkcbl	55	30	ligands	ligand	NNS
cord-277648-9kxwkcbl	55	31	'	'	''
cord-277648-9kxwkcbl	55	32	as	as	IN
cord-277648-9kxwkcbl	55	33	potential	potential	JJ
cord-277648-9kxwkcbl	55	34	key	key	JJ
cord-277648-9kxwkcbl	55	35	regulators	regulator	NNS
cord-277648-9kxwkcbl	55	36	specific	specific	JJ
cord-277648-9kxwkcbl	55	37	to	to	IN
cord-277648-9kxwkcbl	55	38	severe	severe	JJ
cord-277648-9kxwkcbl	55	39	disease	disease	NN
cord-277648-9kxwkcbl	55	40	.	.	.
cord-277648-9kxwkcbl	56	1	Our	-PRON-	PRP$
cord-277648-9kxwkcbl	56	2	integrative	integrative	JJ
cord-277648-9kxwkcbl	56	3	analysis	analysis	NN
cord-277648-9kxwkcbl	56	4	adds	add	VBZ
cord-277648-9kxwkcbl	56	5	to	to	IN
cord-277648-9kxwkcbl	56	6	a	a	DT
cord-277648-9kxwkcbl	56	7	growing	grow	VBG
cord-277648-9kxwkcbl	56	8	knowledge	knowledge	NN
cord-277648-9kxwkcbl	56	9	-	-	HYPH
cord-277648-9kxwkcbl	56	10	base	base	NN
cord-277648-9kxwkcbl	56	11	and	and	CC
cord-277648-9kxwkcbl	56	12	contributes	contribute	VBZ
cord-277648-9kxwkcbl	56	13	to	to	IN
cord-277648-9kxwkcbl	56	14	a	a	DT
cord-277648-9kxwkcbl	56	15	finer	fine	JJR
cord-277648-9kxwkcbl	56	16	understanding	understanding	NN
cord-277648-9kxwkcbl	56	17	of	of	IN
cord-277648-9kxwkcbl	56	18	the	the	DT
cord-277648-9kxwkcbl	56	19	mechanisms	mechanism	NNS
cord-277648-9kxwkcbl	56	20	that	that	WDT
cord-277648-9kxwkcbl	56	21	drive	drive	VBP
cord-277648-9kxwkcbl	56	22	ARDS	ARDS	NNP
cord-277648-9kxwkcbl	56	23	-	-	HYPH
cord-277648-9kxwkcbl	56	24	related	relate	VBN
cord-277648-9kxwkcbl	56	25	immune	immune	JJ
cord-277648-9kxwkcbl	56	26	dysregulation	dysregulation	NN
cord-277648-9kxwkcbl	56	27	in	in	IN
cord-277648-9kxwkcbl	56	28	severe	severe	JJ
cord-277648-9kxwkcbl	56	29	COVID-19	covid-19	NN
cord-277648-9kxwkcbl	56	30	.	.	.
cord-277648-9kxwkcbl	57	1	Our	-PRON-	PRP$
cord-277648-9kxwkcbl	57	2	findings	finding	NNS
cord-277648-9kxwkcbl	57	3	may	may	MD
cord-277648-9kxwkcbl	57	4	guide	guide	VB
cord-277648-9kxwkcbl	57	5	future	future	JJ
cord-277648-9kxwkcbl	57	6	work	work	NN
cord-277648-9kxwkcbl	57	7	informing	inform	VBG
cord-277648-9kxwkcbl	57	8	potential	potential	JJ
cord-277648-9kxwkcbl	57	9	interventional	interventional	JJ
cord-277648-9kxwkcbl	57	10	strategies	strategy	NNS
cord-277648-9kxwkcbl	57	11	to	to	TO
cord-277648-9kxwkcbl	57	12	improve	improve	VB
cord-277648-9kxwkcbl	57	13	patient	patient	JJ
cord-277648-9kxwkcbl	57	14	outcomes	outcome	NNS
cord-277648-9kxwkcbl	57	15	as	as	IN
cord-277648-9kxwkcbl	57	16	the	the	DT
cord-277648-9kxwkcbl	57	17	COVID-19	COVID-19	NNP
cord-277648-9kxwkcbl	57	18	pandemic	pandemic	NN
cord-277648-9kxwkcbl	57	19	continues	continue	VBZ
cord-277648-9kxwkcbl	57	20	to	to	TO
cord-277648-9kxwkcbl	57	21	unfold	unfold	VB
cord-277648-9kxwkcbl	57	22	.	.	.
cord-277648-9kxwkcbl	58	1	Severe	severe	JJ
cord-277648-9kxwkcbl	58	2	COVID-19	COVID-19	NNP
cord-277648-9kxwkcbl	58	3	has	have	VBZ
cord-277648-9kxwkcbl	58	4	been	be	VBN
cord-277648-9kxwkcbl	58	5	thought	think	VBN
cord-277648-9kxwkcbl	58	6	to	to	TO
cord-277648-9kxwkcbl	58	7	result	result	VB
cord-277648-9kxwkcbl	58	8	in	in	IN
cord-277648-9kxwkcbl	58	9	profound	profound	JJ
cord-277648-9kxwkcbl	58	10	immune	immune	JJ
cord-277648-9kxwkcbl	58	11	dysregulation	dysregulation	NN
cord-277648-9kxwkcbl	58	12	at	at	IN
cord-277648-9kxwkcbl	58	13	both	both	CC
cord-277648-9kxwkcbl	58	14	a	a	DT
cord-277648-9kxwkcbl	58	15	local	local	JJ
cord-277648-9kxwkcbl	58	16	and	and	CC
cord-277648-9kxwkcbl	58	17	systemic	systemic	JJ
cord-277648-9kxwkcbl	58	18	level	level	NN
cord-277648-9kxwkcbl	58	19	.	.	.
cord-277648-9kxwkcbl	59	1	Here	here	RB
cord-277648-9kxwkcbl	59	2	,	,	,
cord-277648-9kxwkcbl	59	3	we	-PRON-	PRP
cord-277648-9kxwkcbl	59	4	performed	perform	VBD
cord-277648-9kxwkcbl	59	5	a	a	DT
cord-277648-9kxwkcbl	59	6	re	re	NN
cord-277648-9kxwkcbl	59	7	-	-	NN
cord-277648-9kxwkcbl	59	8	analysis	analysis	NN
cord-277648-9kxwkcbl	59	9	of	of	IN
cord-277648-9kxwkcbl	59	10	single	single	JJ
cord-277648-9kxwkcbl	59	11	-	-	HYPH
cord-277648-9kxwkcbl	59	12	cell	cell	NN
cord-277648-9kxwkcbl	59	13	RNA	rna	NN
cord-277648-9kxwkcbl	59	14	sequencing	sequencing	NN
cord-277648-9kxwkcbl	59	15	(	(	-LRB-
cord-277648-9kxwkcbl	59	16	scRNA	scRNA	NNP
cord-277648-9kxwkcbl	59	17	-	-	HYPH
cord-277648-9kxwkcbl	59	18	seq	seq	NN
cord-277648-9kxwkcbl	59	19	)	)	-RRB-
cord-277648-9kxwkcbl	59	20	data	datum	NNS
cord-277648-9kxwkcbl	59	21	to	to	TO
cord-277648-9kxwkcbl	59	22	identify	identify	VB
cord-277648-9kxwkcbl	59	23	common	common	JJ
cord-277648-9kxwkcbl	59	24	and	and	CC
cord-277648-9kxwkcbl	59	25	compartment	compartment	NN
cord-277648-9kxwkcbl	59	26	-	-	HYPH
cord-277648-9kxwkcbl	59	27	specific	specific	JJ
cord-277648-9kxwkcbl	59	28	signatures	signature	NNS
cord-277648-9kxwkcbl	59	29	of	of	IN
cord-277648-9kxwkcbl	59	30	COVID-19	covid-19	JJ
cord-277648-9kxwkcbl	59	31	disease	disease	NN
cord-277648-9kxwkcbl	59	32	severity	severity	NN
cord-277648-9kxwkcbl	59	33	.	.	.
cord-277648-9kxwkcbl	60	1	We	-PRON-	PRP
cord-277648-9kxwkcbl	60	2	used	use	VBD
cord-277648-9kxwkcbl	60	3	identical	identical	JJ
cord-277648-9kxwkcbl	60	4	methods	method	NNS
cord-277648-9kxwkcbl	60	5	to	to	TO
cord-277648-9kxwkcbl	60	6	separately	separately	RB
cord-277648-9kxwkcbl	60	7	analyze	analyze	VB
cord-277648-9kxwkcbl	60	8	multi	multi	JJ
cord-277648-9kxwkcbl	60	9	-	-	JJ
cord-277648-9kxwkcbl	60	10	donor	donor	JJ
cord-277648-9kxwkcbl	60	11	scRNA	scRNA	NNS
cord-277648-9kxwkcbl	60	12	-	-	HYPH
cord-277648-9kxwkcbl	60	13	seq	seq	NN
cord-277648-9kxwkcbl	60	14	datasets	dataset	NNS
cord-277648-9kxwkcbl	60	15	from	from	IN
cord-277648-9kxwkcbl	60	16	bronchoalveolar	bronchoalveolar	NNP
cord-277648-9kxwkcbl	60	17	lavage	lavage	NN
cord-277648-9kxwkcbl	60	18	fluid	fluid	NN
cord-277648-9kxwkcbl	60	19	(	(	-LRB-
cord-277648-9kxwkcbl	60	20	BALF	BALF	NNP
cord-277648-9kxwkcbl	60	21	)	)	-RRB-
cord-277648-9kxwkcbl	60	22	and	and	CC
cord-277648-9kxwkcbl	60	23	peripheral	peripheral	JJ
cord-277648-9kxwkcbl	60	24	blood	blood	NN
cord-277648-9kxwkcbl	60	25	mononuclear	mononuclear	NN
cord-277648-9kxwkcbl	60	26	cells	cell	NNS
cord-277648-9kxwkcbl	60	27	(	(	-LRB-
cord-277648-9kxwkcbl	60	28	PBMCs	pbmc	NNS
cord-277648-9kxwkcbl	60	29	)	)	-RRB-
cord-277648-9kxwkcbl	60	30	in	in	IN
cord-277648-9kxwkcbl	60	31	COVID-19	COVID-19	NNP
cord-277648-9kxwkcbl	60	32	patients	patient	NNS
cord-277648-9kxwkcbl	60	33	classified	classify	VBN
cord-277648-9kxwkcbl	60	34	by	by	IN
cord-277648-9kxwkcbl	60	35	severity	severity	NN
cord-277648-9kxwkcbl	60	36	strata	strata	NN
cord-277648-9kxwkcbl	60	37	as	as	RB
cord-277648-9kxwkcbl	60	38	well	well	RB
cord-277648-9kxwkcbl	60	39	as	as	IN
cord-277648-9kxwkcbl	60	40	healthy	healthy	JJ
cord-277648-9kxwkcbl	60	41	control	control	NN
cord-277648-9kxwkcbl	60	42	subjects	subject	NNS
cord-277648-9kxwkcbl	60	43	to	to	TO
cord-277648-9kxwkcbl	60	44	investigate	investigate	VB
cord-277648-9kxwkcbl	60	45	severity	severity	NN
cord-277648-9kxwkcbl	60	46	-	-	HYPH
cord-277648-9kxwkcbl	60	47	specific	specific	JJ
cord-277648-9kxwkcbl	60	48	immune	immune	JJ
cord-277648-9kxwkcbl	60	49	dysregulation	dysregulation	NN
cord-277648-9kxwkcbl	60	50	in	in	IN
cord-277648-9kxwkcbl	60	51	the	the	DT
cord-277648-9kxwkcbl	60	52	lung	lung	NN
cord-277648-9kxwkcbl	60	53	and	and	CC
cord-277648-9kxwkcbl	60	54	periphery	periphery	NN
cord-277648-9kxwkcbl	60	55	.	.	.
cord-277648-9kxwkcbl	61	1	BALF	BALF	NNP
cord-277648-9kxwkcbl	61	2	and	and	CC
cord-277648-9kxwkcbl	61	3	PBMC	PBMC	NNP
cord-277648-9kxwkcbl	61	4	raw	raw	JJ
cord-277648-9kxwkcbl	61	5	gene	gene	NN
cord-277648-9kxwkcbl	61	6	-	-	HYPH
cord-277648-9kxwkcbl	61	7	barcode	barcode	NN
cord-277648-9kxwkcbl	61	8	matrices	matrix	NNS
cord-277648-9kxwkcbl	61	9	were	be	VBD
cord-277648-9kxwkcbl	61	10	downloaded	download	VBN
cord-277648-9kxwkcbl	61	11	from	from	IN
cord-277648-9kxwkcbl	61	12	separate	separate	JJ
cord-277648-9kxwkcbl	61	13	studies	study	NNS
cord-277648-9kxwkcbl	61	14	in	in	IN
cord-277648-9kxwkcbl	61	15	the	the	DT
cord-277648-9kxwkcbl	61	16	GEO	GEO	NNP
cord-277648-9kxwkcbl	61	17	[	[	-LRB-
cord-277648-9kxwkcbl	61	18	27	27	CD
cord-277648-9kxwkcbl	61	19	,	,	,
cord-277648-9kxwkcbl	61	20	32	32	CD
cord-277648-9kxwkcbl	61	21	]	]	-RRB-
cord-277648-9kxwkcbl	61	22	.	.	.
cord-277648-9kxwkcbl	62	1	The	the	DT
cord-277648-9kxwkcbl	62	2	BALF	BALF	NNP
cord-277648-9kxwkcbl	62	3	dataset	dataset	NN
cord-277648-9kxwkcbl	62	4	consisted	consist	VBD
cord-277648-9kxwkcbl	62	5	of	of	IN
cord-277648-9kxwkcbl	62	6	9	9	CD
cord-277648-9kxwkcbl	62	7	patients	patient	NNS
cord-277648-9kxwkcbl	62	8	(	(	-LRB-
cord-277648-9kxwkcbl	62	9	6	6	CD
cord-277648-9kxwkcbl	62	10	severe	severe	JJ
cord-277648-9kxwkcbl	62	11	and	and	CC
cord-277648-9kxwkcbl	62	12	3	3	CD
cord-277648-9kxwkcbl	62	13	moderate	moderate	JJ
cord-277648-9kxwkcbl	62	14	)	)	-RRB-
cord-277648-9kxwkcbl	62	15	and	and	CC
cord-277648-9kxwkcbl	62	16	4	4	CD
cord-277648-9kxwkcbl	62	17	healthy	healthy	JJ
cord-277648-9kxwkcbl	62	18	control	control	NN
cord-277648-9kxwkcbl	62	19	donors	donor	NNS
cord-277648-9kxwkcbl	62	20	,	,	,
cord-277648-9kxwkcbl	62	21	while	while	IN
cord-277648-9kxwkcbl	62	22	the	the	DT
cord-277648-9kxwkcbl	62	23	PBMC	PBMC	NNP
cord-277648-9kxwkcbl	62	24	dataset	dataset	NN
cord-277648-9kxwkcbl	62	25	consisted	consist	VBD
cord-277648-9kxwkcbl	62	26	of	of	IN
cord-277648-9kxwkcbl	62	27	7	7	CD
cord-277648-9kxwkcbl	62	28	patients	patient	NNS
cord-277648-9kxwkcbl	62	29	(	(	-LRB-
cord-277648-9kxwkcbl	62	30	4	4	CD
cord-277648-9kxwkcbl	62	31	patients	patient	NNS
cord-277648-9kxwkcbl	62	32	with	with	IN
cord-277648-9kxwkcbl	62	33	ARDS	ARDS	NNP
cord-277648-9kxwkcbl	62	34	,	,	,
cord-277648-9kxwkcbl	62	35	4	4	CD
cord-277648-9kxwkcbl	62	36	patients	patient	NNS
cord-277648-9kxwkcbl	62	37	without	without	IN
cord-277648-9kxwkcbl	62	38	ARDS	ARDS	NNP
cord-277648-9kxwkcbl	62	39	,	,	,
cord-277648-9kxwkcbl	62	40	where	where	WRB
cord-277648-9kxwkcbl	62	41	one	one	CD
cord-277648-9kxwkcbl	62	42	patient	patient	NN
cord-277648-9kxwkcbl	62	43	who	who	WP
cord-277648-9kxwkcbl	62	44	was	be	VBD
cord-277648-9kxwkcbl	62	45	sampled	sample	VBN
cord-277648-9kxwkcbl	62	46	twice	twice	RB
cord-277648-9kxwkcbl	62	47	fell	fall	VBD
cord-277648-9kxwkcbl	62	48	within	within	IN
cord-277648-9kxwkcbl	62	49	both	both	DT
cord-277648-9kxwkcbl	62	50	groups	group	NNS
cord-277648-9kxwkcbl	62	51	at	at	IN
cord-277648-9kxwkcbl	62	52	different	different	JJ
cord-277648-9kxwkcbl	62	53	stages	stage	NNS
cord-277648-9kxwkcbl	62	54	of	of	IN
cord-277648-9kxwkcbl	62	55	the	the	DT
cord-277648-9kxwkcbl	62	56	disease	disease	NN
cord-277648-9kxwkcbl	62	57	course	course	NN
cord-277648-9kxwkcbl	62	58	)	)	-RRB-
cord-277648-9kxwkcbl	62	59	and	and	CC
cord-277648-9kxwkcbl	62	60	6	6	CD
cord-277648-9kxwkcbl	62	61	healthy	healthy	JJ
cord-277648-9kxwkcbl	62	62	control	control	NN
cord-277648-9kxwkcbl	62	63	donors	donor	NNS
cord-277648-9kxwkcbl	62	64	.	.	.
cord-277648-9kxwkcbl	63	1	We	-PRON-	PRP
cord-277648-9kxwkcbl	63	2	performed	perform	VBD
cord-277648-9kxwkcbl	63	3	our	-PRON-	PRP$
cord-277648-9kxwkcbl	63	4	analyses	analysis	NNS
cord-277648-9kxwkcbl	63	5	on	on	IN
cord-277648-9kxwkcbl	63	6	BALF	BALF	NNP
cord-277648-9kxwkcbl	63	7	and	and	CC
cord-277648-9kxwkcbl	63	8	PBMC	PBMC	NNP
cord-277648-9kxwkcbl	63	9	datasets	dataset	NNS
cord-277648-9kxwkcbl	63	10	separately	separately	RB
cord-277648-9kxwkcbl	63	11	with	with	IN
cord-277648-9kxwkcbl	63	12	the	the	DT
cord-277648-9kxwkcbl	63	13	goal	goal	NN
cord-277648-9kxwkcbl	63	14	of	of	IN
cord-277648-9kxwkcbl	63	15	identifying	identify	VBG
cord-277648-9kxwkcbl	63	16	common	common	JJ
cord-277648-9kxwkcbl	63	17	and	and	CC
cord-277648-9kxwkcbl	63	18	compartment	compartment	NN
cord-277648-9kxwkcbl	63	19	-	-	HYPH
cord-277648-9kxwkcbl	63	20	specific	specific	JJ
cord-277648-9kxwkcbl	63	21	gene	gene	NN
cord-277648-9kxwkcbl	63	22	signatures	signature	NNS
cord-277648-9kxwkcbl	63	23	.	.	.
cord-277648-9kxwkcbl	64	1	To	to	TO
cord-277648-9kxwkcbl	64	2	analyze	analyze	VB
cord-277648-9kxwkcbl	64	3	the	the	DT
cord-277648-9kxwkcbl	64	4	compositional	compositional	JJ
cord-277648-9kxwkcbl	64	5	changes	change	NNS
cord-277648-9kxwkcbl	64	6	in	in	IN
cord-277648-9kxwkcbl	64	7	cell	cell	NN
cord-277648-9kxwkcbl	64	8	populations	population	NNS
cord-277648-9kxwkcbl	64	9	occurring	occur	VBG
cord-277648-9kxwkcbl	64	10	during	during	IN
cord-277648-9kxwkcbl	64	11	severe	severe	JJ
cord-277648-9kxwkcbl	64	12	COVID-19	COVID-19	NNP
cord-277648-9kxwkcbl	64	13	,	,	,
cord-277648-9kxwkcbl	64	14	we	-PRON-	PRP
cord-277648-9kxwkcbl	64	15	first	first	RB
cord-277648-9kxwkcbl	64	16	sought	seek	VBD
cord-277648-9kxwkcbl	64	17	to	to	TO
cord-277648-9kxwkcbl	64	18	identify	identify	VB
cord-277648-9kxwkcbl	64	19	clusters	cluster	NNS
cord-277648-9kxwkcbl	64	20	in	in	IN
cord-277648-9kxwkcbl	64	21	transcriptionally	transcriptionally	RB
cord-277648-9kxwkcbl	64	22	heterogeneous	heterogeneous	JJ
cord-277648-9kxwkcbl	64	23	scRNA	scRNA	NNP
cord-277648-9kxwkcbl	64	24	-	-	HYPH
cord-277648-9kxwkcbl	64	25	seq	seq	NN
cord-277648-9kxwkcbl	64	26	data	datum	NNS
cord-277648-9kxwkcbl	64	27	of	of	IN
cord-277648-9kxwkcbl	64	28	the	the	DT
cord-277648-9kxwkcbl	64	29	lung	lung	NN
cord-277648-9kxwkcbl	64	30	.	.	.
cord-277648-9kxwkcbl	65	1	After	after	IN
cord-277648-9kxwkcbl	65	2	preprocessing	preprocesse	VBG
cord-277648-9kxwkcbl	65	3	raw	raw	JJ
cord-277648-9kxwkcbl	65	4	BALF	BALF	NNP
cord-277648-9kxwkcbl	65	5	gene	gene	NN
cord-277648-9kxwkcbl	65	6	-	-	HYPH
cord-277648-9kxwkcbl	65	7	barcode	barcode	NN
cord-277648-9kxwkcbl	65	8	matrices	matrix	NNS
cord-277648-9kxwkcbl	65	9	,	,	,
cord-277648-9kxwkcbl	65	10	a	a	DT
cord-277648-9kxwkcbl	65	11	filtered	filter	VBN
cord-277648-9kxwkcbl	65	12	dataset	dataset	NN
cord-277648-9kxwkcbl	65	13	consisting	consisting	NN
cord-277648-9kxwkcbl	65	14	of	of	IN
cord-277648-9kxwkcbl	65	15	66,452	66,452	CD
cord-277648-9kxwkcbl	65	16	cells	cell	NNS
cord-277648-9kxwkcbl	65	17	was	be	VBD
cord-277648-9kxwkcbl	65	18	clustered	cluster	VBN
cord-277648-9kxwkcbl	65	19	using	use	VBG
cord-277648-9kxwkcbl	65	20	Seurat	Seurat	NNP
cord-277648-9kxwkcbl	65	21	and	and	CC
cord-277648-9kxwkcbl	65	22	visualized	visualize	VBN
cord-277648-9kxwkcbl	65	23	by	by	IN
cord-277648-9kxwkcbl	65	24	uniform	uniform	JJ
cord-277648-9kxwkcbl	65	25	manifold	manifold	JJ
cord-277648-9kxwkcbl	65	26	approximation	approximation	NN
cord-277648-9kxwkcbl	65	27	and	and	CC
cord-277648-9kxwkcbl	65	28	projection	projection	NN
cord-277648-9kxwkcbl	65	29	(	(	-LRB-
cord-277648-9kxwkcbl	65	30	UMAP	UMAP	NNP
cord-277648-9kxwkcbl	65	31	)	)	-RRB-
cord-277648-9kxwkcbl	65	32	,	,	,
cord-277648-9kxwkcbl	65	33	as	as	IN
cord-277648-9kxwkcbl	65	34	shown	show	VBN
cord-277648-9kxwkcbl	65	35	in	in	IN
cord-277648-9kxwkcbl	65	36	Figure	Figure	NNP
cord-277648-9kxwkcbl	65	37	1A	1a	CD
cord-277648-9kxwkcbl	65	38	.	.	.
cord-277648-9kxwkcbl	66	1	A	a	DT
cord-277648-9kxwkcbl	66	2	total	total	NN
cord-277648-9kxwkcbl	66	3	of	of	IN
cord-277648-9kxwkcbl	66	4	33	33	CD
cord-277648-9kxwkcbl	66	5	clusters	cluster	NNS
cord-277648-9kxwkcbl	66	6	were	be	VBD
cord-277648-9kxwkcbl	66	7	identified	identify	VBN
cord-277648-9kxwkcbl	66	8	showing	show	VBG
cord-277648-9kxwkcbl	66	9	distinct	distinct	JJ
cord-277648-9kxwkcbl	66	10	separation	separation	NN
cord-277648-9kxwkcbl	66	11	in	in	IN
cord-277648-9kxwkcbl	66	12	a	a	DT
cord-277648-9kxwkcbl	66	13	two	two	CD
cord-277648-9kxwkcbl	66	14	-	-	HYPH
cord-277648-9kxwkcbl	66	15	dimensional	dimensional	JJ
cord-277648-9kxwkcbl	66	16	UMAP	umap	JJ
cord-277648-9kxwkcbl	66	17	space	space	NN
cord-277648-9kxwkcbl	66	18	.	.	.
cord-277648-9kxwkcbl	67	1	Annotation	annotation	NN
cord-277648-9kxwkcbl	67	2	of	of	IN
cord-277648-9kxwkcbl	67	3	these	these	DT
cord-277648-9kxwkcbl	67	4	clusters	cluster	NNS
cord-277648-9kxwkcbl	67	5	based	base	VBN
cord-277648-9kxwkcbl	67	6	on	on	IN
cord-277648-9kxwkcbl	67	7	the	the	DT
cord-277648-9kxwkcbl	67	8	expression	expression	NN
cord-277648-9kxwkcbl	67	9	of	of	IN
cord-277648-9kxwkcbl	67	10	canonical	canonical	JJ
cord-277648-9kxwkcbl	67	11	cell	cell	NN
cord-277648-9kxwkcbl	67	12	type	type	NN
cord-277648-9kxwkcbl	67	13	markers	marker	NNS
cord-277648-9kxwkcbl	67	14	showed	show	VBD
cord-277648-9kxwkcbl	67	15	the	the	DT
cord-277648-9kxwkcbl	67	16	presence	presence	NN
cord-277648-9kxwkcbl	67	17	of	of	IN
cord-277648-9kxwkcbl	67	18	myeloid	myeloid	NN
cord-277648-9kxwkcbl	67	19	cells	cell	NNS
cord-277648-9kxwkcbl	67	20	,	,	,
cord-277648-9kxwkcbl	67	21	lymphoid	lymphoid	JJ
cord-277648-9kxwkcbl	67	22	cells	cell	NNS
cord-277648-9kxwkcbl	67	23	,	,	,
cord-277648-9kxwkcbl	67	24	and	and	CC
cord-277648-9kxwkcbl	67	25	epithelial	epithelial	JJ
cord-277648-9kxwkcbl	67	26	cells	cell	NNS
cord-277648-9kxwkcbl	67	27	,	,	,
cord-277648-9kxwkcbl	67	28	closely	closely	RB
cord-277648-9kxwkcbl	67	29	matching	match	VBG
cord-277648-9kxwkcbl	67	30	the	the	DT
cord-277648-9kxwkcbl	67	31	cell	cell	NN
cord-277648-9kxwkcbl	67	32	types	type	NNS
cord-277648-9kxwkcbl	67	33	found	find	VBN
cord-277648-9kxwkcbl	67	34	by	by	IN
cord-277648-9kxwkcbl	67	35	the	the	DT
cord-277648-9kxwkcbl	67	36	original	original	JJ
cord-277648-9kxwkcbl	67	37	publication	publication	NN
cord-277648-9kxwkcbl	67	38	[	[	-LRB-
cord-277648-9kxwkcbl	67	39	27	27	CD
cord-277648-9kxwkcbl	67	40	]	]	-RRB-
cord-277648-9kxwkcbl	67	41	.	.	.
cord-277648-9kxwkcbl	68	1	Of	of	IN
cord-277648-9kxwkcbl	68	2	13	13	CD
cord-277648-9kxwkcbl	68	3	annotated	annotated	JJ
cord-277648-9kxwkcbl	68	4	cell	cell	NN
cord-277648-9kxwkcbl	68	5	types	type	NNS
cord-277648-9kxwkcbl	68	6	,	,	,
cord-277648-9kxwkcbl	68	7	12	12	CD
cord-277648-9kxwkcbl	68	8	contained	contain	VBD
cord-277648-9kxwkcbl	68	9	cells	cell	NNS
cord-277648-9kxwkcbl	68	10	from	from	IN
cord-277648-9kxwkcbl	68	11	moderate	moderate	JJ
cord-277648-9kxwkcbl	68	12	,	,	,
cord-277648-9kxwkcbl	68	13	severe	severe	JJ
cord-277648-9kxwkcbl	68	14	,	,	,
cord-277648-9kxwkcbl	68	15	and	and	CC
cord-277648-9kxwkcbl	68	16	control	control	NN
cord-277648-9kxwkcbl	68	17	donors	donor	NNS
cord-277648-9kxwkcbl	68	18	,	,	,
cord-277648-9kxwkcbl	68	19	with	with	IN
cord-277648-9kxwkcbl	68	20	the	the	DT
cord-277648-9kxwkcbl	68	21	exception	exception	NN
cord-277648-9kxwkcbl	68	22	of	of	IN
cord-277648-9kxwkcbl	68	23	plasma	plasma	NN
cord-277648-9kxwkcbl	68	24	cells	cell	NNS
cord-277648-9kxwkcbl	68	25	which	which	WDT
cord-277648-9kxwkcbl	68	26	were	be	VBD
cord-277648-9kxwkcbl	68	27	not	not	RB
cord-277648-9kxwkcbl	68	28	recovered	recover	VBN
cord-277648-9kxwkcbl	68	29	from	from	IN
cord-277648-9kxwkcbl	68	30	moderate	moderate	JJ
cord-277648-9kxwkcbl	68	31	donors	donor	NNS
cord-277648-9kxwkcbl	68	32	(	(	-LRB-
cord-277648-9kxwkcbl	68	33	Figure	figure	NN
cord-277648-9kxwkcbl	68	34	S1A	s1a	NN
cord-277648-9kxwkcbl	68	35	)	)	-RRB-
cord-277648-9kxwkcbl	68	36	.	.	.
cord-277648-9kxwkcbl	69	1	Compositional	compositional	JJ
cord-277648-9kxwkcbl	69	2	changes	change	NNS
cord-277648-9kxwkcbl	69	3	across	across	IN
cord-277648-9kxwkcbl	69	4	disease	disease	NN
cord-277648-9kxwkcbl	69	5	severity	severity	NN
cord-277648-9kxwkcbl	69	6	categories	category	NNS
cord-277648-9kxwkcbl	69	7	were	be	VBD
cord-277648-9kxwkcbl	69	8	assessed	assess	VBN
cord-277648-9kxwkcbl	69	9	by	by	IN
cord-277648-9kxwkcbl	69	10	z	z	NN
cord-277648-9kxwkcbl	69	11	-	-	HYPH
cord-277648-9kxwkcbl	69	12	scored	score	VBN
cord-277648-9kxwkcbl	69	13	percentages	percentage	NNS
cord-277648-9kxwkcbl	69	14	of	of	IN
cord-277648-9kxwkcbl	69	15	cell	cell	NN
cord-277648-9kxwkcbl	69	16	types	type	NNS
cord-277648-9kxwkcbl	69	17	in	in	IN
cord-277648-9kxwkcbl	69	18	each	each	DT
cord-277648-9kxwkcbl	69	19	donor	donor	NN
cord-277648-9kxwkcbl	69	20	sample	sample	NN
cord-277648-9kxwkcbl	69	21	.	.	.
cord-277648-9kxwkcbl	70	1	Analyzing	analyze	VBG
cord-277648-9kxwkcbl	70	2	BALF	BALF	NNP
cord-277648-9kxwkcbl	70	3	compositional	compositional	JJ
cord-277648-9kxwkcbl	70	4	changes	change	NNS
cord-277648-9kxwkcbl	70	5	showed	show	VBD
cord-277648-9kxwkcbl	70	6	trends	trend	NNS
cord-277648-9kxwkcbl	70	7	of	of	IN
cord-277648-9kxwkcbl	70	8	increased	increase	VBN
cord-277648-9kxwkcbl	70	9	donor	donor	NN
cord-277648-9kxwkcbl	70	10	specific	specific	JJ
cord-277648-9kxwkcbl	70	11	percentages	percentage	NNS
cord-277648-9kxwkcbl	70	12	of	of	IN
cord-277648-9kxwkcbl	70	13	NK	NK	NNP
cord-277648-9kxwkcbl	70	14	cells	cell	NNS
cord-277648-9kxwkcbl	70	15	,	,	,
cord-277648-9kxwkcbl	70	16	mixed	mix	VBN
cord-277648-9kxwkcbl	70	17	T	t	NN
cord-277648-9kxwkcbl	70	18	cells	cell	NNS
cord-277648-9kxwkcbl	70	19	,	,	,
cord-277648-9kxwkcbl	70	20	and	and	CC
cord-277648-9kxwkcbl	70	21	plasmacytoid	plasmacytoid	NNP
cord-277648-9kxwkcbl	70	22	dendritic	dendritic	JJ
cord-277648-9kxwkcbl	70	23	cells	cell	NNS
cord-277648-9kxwkcbl	70	24	(	(	-LRB-
cord-277648-9kxwkcbl	70	25	pDCs	pDCs	NNP
cord-277648-9kxwkcbl	70	26	)	)	-RRB-
cord-277648-9kxwkcbl	70	27	in	in	IN
cord-277648-9kxwkcbl	70	28	moderate	moderate	JJ
cord-277648-9kxwkcbl	70	29	donors	donor	NNS
cord-277648-9kxwkcbl	70	30	over	over	IN
cord-277648-9kxwkcbl	70	31	control	control	NN
cord-277648-9kxwkcbl	70	32	and	and	CC
cord-277648-9kxwkcbl	70	33	severe	severe	JJ
cord-277648-9kxwkcbl	70	34	donors	donor	NNS
cord-277648-9kxwkcbl	70	35	as	as	IN
cord-277648-9kxwkcbl	70	36	displayed	display	VBN
cord-277648-9kxwkcbl	70	37	in	in	IN
cord-277648-9kxwkcbl	70	38	the	the	DT
cord-277648-9kxwkcbl	70	39	Figure	figure	NN
cord-277648-9kxwkcbl	70	40	1A	1a	NN
cord-277648-9kxwkcbl	70	41	heatmap	heatmap	NN
cord-277648-9kxwkcbl	70	42	.	.	.
cord-277648-9kxwkcbl	71	1	We	-PRON-	PRP
cord-277648-9kxwkcbl	71	2	next	next	RB
cord-277648-9kxwkcbl	71	3	preprocessed	preprocesse	VBD
cord-277648-9kxwkcbl	71	4	raw	raw	JJ
cord-277648-9kxwkcbl	71	5	PBMC	PBMC	NNP
cord-277648-9kxwkcbl	71	6	gene	gene	NN
cord-277648-9kxwkcbl	71	7	-	-	HYPH
cord-277648-9kxwkcbl	71	8	barcode	barcode	NN
cord-277648-9kxwkcbl	71	9	matrices	matrix	NNS
cord-277648-9kxwkcbl	71	10	,	,	,
cord-277648-9kxwkcbl	71	11	resulting	result	VBG
cord-277648-9kxwkcbl	71	12	in	in	IN
cord-277648-9kxwkcbl	71	13	a	a	DT
cord-277648-9kxwkcbl	71	14	filtered	filter	VBN
cord-277648-9kxwkcbl	71	15	dataset	dataset	NN
cord-277648-9kxwkcbl	71	16	of	of	IN
cord-277648-9kxwkcbl	71	17	31,957	31,957	CD
cord-277648-9kxwkcbl	71	18	cells	cell	NNS
cord-277648-9kxwkcbl	71	19	.	.	.
cord-277648-9kxwkcbl	72	1	The	the	DT
cord-277648-9kxwkcbl	72	2	blood	blood	NN
cord-277648-9kxwkcbl	72	3	single	single	JJ
cord-277648-9kxwkcbl	72	4	-	-	HYPH
cord-277648-9kxwkcbl	72	5	cell	cell	NN
cord-277648-9kxwkcbl	72	6	landscape	landscape	NN
cord-277648-9kxwkcbl	72	7	was	be	VBD
cord-277648-9kxwkcbl	72	8	visualized	visualize	VBN
cord-277648-9kxwkcbl	72	9	by	by	IN
cord-277648-9kxwkcbl	72	10	UMAP	UMAP	NNP
cord-277648-9kxwkcbl	72	11	(	(	-LRB-
cord-277648-9kxwkcbl	72	12	Figure	figure	NN
cord-277648-9kxwkcbl	72	13	1B	1b	CD
cord-277648-9kxwkcbl	72	14	)	)	-RRB-
cord-277648-9kxwkcbl	72	15	.	.	.
cord-277648-9kxwkcbl	73	1	A	a	DT
cord-277648-9kxwkcbl	73	2	total	total	NN
cord-277648-9kxwkcbl	73	3	of	of	IN
cord-277648-9kxwkcbl	73	4	26	26	CD
cord-277648-9kxwkcbl	73	5	clusters	cluster	NNS
cord-277648-9kxwkcbl	73	6	were	be	VBD
cord-277648-9kxwkcbl	73	7	identified	identify	VBN
cord-277648-9kxwkcbl	73	8	,	,	,
cord-277648-9kxwkcbl	73	9	showing	show	VBG
cord-277648-9kxwkcbl	73	10	distinct	distinct	JJ
cord-277648-9kxwkcbl	73	11	populations	population	NNS
cord-277648-9kxwkcbl	73	12	in	in	IN
cord-277648-9kxwkcbl	73	13	a	a	DT
cord-277648-9kxwkcbl	73	14	two	two	CD
cord-277648-9kxwkcbl	73	15	-	-	HYPH
cord-277648-9kxwkcbl	73	16	dimensional	dimensional	JJ
cord-277648-9kxwkcbl	73	17	UMAP	umap	JJ
cord-277648-9kxwkcbl	73	18	space	space	NN
cord-277648-9kxwkcbl	73	19	.	.	.
cord-277648-9kxwkcbl	74	1	Annotation	annotation	NN
cord-277648-9kxwkcbl	74	2	of	of	IN
cord-277648-9kxwkcbl	74	3	these	these	DT
cord-277648-9kxwkcbl	74	4	clusters	cluster	NNS
cord-277648-9kxwkcbl	74	5	revealed	reveal	VBD
cord-277648-9kxwkcbl	74	6	the	the	DT
cord-277648-9kxwkcbl	74	7	presence	presence	NN
cord-277648-9kxwkcbl	74	8	of	of	IN
cord-277648-9kxwkcbl	74	9	myeloid	myeloid	NN
cord-277648-9kxwkcbl	74	10	cells	cell	NNS
cord-277648-9kxwkcbl	74	11	and	and	CC
cord-277648-9kxwkcbl	74	12	lymphoid	lymphoid	JJ
cord-277648-9kxwkcbl	74	13	cells	cell	NNS
cord-277648-9kxwkcbl	74	14	,	,	,
cord-277648-9kxwkcbl	74	15	roughly	roughly	RB
cord-277648-9kxwkcbl	74	16	matching	match	VBG
cord-277648-9kxwkcbl	74	17	the	the	DT
cord-277648-9kxwkcbl	74	18	cell	cell	NN
cord-277648-9kxwkcbl	74	19	types	type	NNS
cord-277648-9kxwkcbl	74	20	found	find	VBN
cord-277648-9kxwkcbl	74	21	by	by	IN
cord-277648-9kxwkcbl	74	22	in	in	IN
cord-277648-9kxwkcbl	74	23	the	the	DT
cord-277648-9kxwkcbl	74	24	original	original	JJ
cord-277648-9kxwkcbl	74	25	publication	publication	NN
cord-277648-9kxwkcbl	74	26	using	use	VBG
cord-277648-9kxwkcbl	74	27	a	a	DT
cord-277648-9kxwkcbl	74	28	different	different	JJ
cord-277648-9kxwkcbl	74	29	method	method	NN
cord-277648-9kxwkcbl	74	30	[	[	-LRB-
cord-277648-9kxwkcbl	74	31	32	32	CD
cord-277648-9kxwkcbl	74	32	]	]	-RRB-
cord-277648-9kxwkcbl	74	33	.	.	.
cord-277648-9kxwkcbl	75	1	We	-PRON-	PRP
cord-277648-9kxwkcbl	75	2	termed	term	VBD
cord-277648-9kxwkcbl	75	3	the	the	DT
cord-277648-9kxwkcbl	75	4	blood	blood	NN
cord-277648-9kxwkcbl	75	5	cells	cell	NNS
cord-277648-9kxwkcbl	75	6	observed	observe	VBN
cord-277648-9kxwkcbl	75	7	in	in	IN
cord-277648-9kxwkcbl	75	8	this	this	DT
cord-277648-9kxwkcbl	75	9	dataset	dataset	NN
cord-277648-9kxwkcbl	75	10	as	as	IN
cord-277648-9kxwkcbl	75	11	"	"	``
cord-277648-9kxwkcbl	75	12	PBMCs	PBMCs	NNP
cord-277648-9kxwkcbl	75	13	"	"	''
cord-277648-9kxwkcbl	75	14	,	,	,
cord-277648-9kxwkcbl	75	15	although	although	IN
cord-277648-9kxwkcbl	75	16	cell	cell	NN
cord-277648-9kxwkcbl	75	17	type	type	NN
cord-277648-9kxwkcbl	75	18	annotation	annotation	NN
cord-277648-9kxwkcbl	75	19	revealed	reveal	VBD
cord-277648-9kxwkcbl	75	20	the	the	DT
cord-277648-9kxwkcbl	75	21	presence	presence	NN
cord-277648-9kxwkcbl	75	22	of	of	IN
cord-277648-9kxwkcbl	75	23	anuclear	anuclear	JJ
cord-277648-9kxwkcbl	75	24	platelets	platelet	NNS
cord-277648-9kxwkcbl	75	25	and	and	CC
cord-277648-9kxwkcbl	75	26	erythrocytes	erythrocyte	NNS
cord-277648-9kxwkcbl	75	27	,	,	,
cord-277648-9kxwkcbl	75	28	as	as	RB
cord-277648-9kxwkcbl	75	29	well	well	RB
cord-277648-9kxwkcbl	75	30	as	as	IN
cord-277648-9kxwkcbl	75	31	polymorphonuclear	polymorphonuclear	JJ
cord-277648-9kxwkcbl	75	32	basophils	basophil	NNS
cord-277648-9kxwkcbl	75	33	and	and	CC
cord-277648-9kxwkcbl	75	34	neutrophils	neutrophil	NNS
cord-277648-9kxwkcbl	75	35	.	.	.
cord-277648-9kxwkcbl	76	1	All	all	DT
cord-277648-9kxwkcbl	76	2	20	20	CD
cord-277648-9kxwkcbl	76	3	annotated	annotated	JJ
cord-277648-9kxwkcbl	76	4	cell	cell	NN
cord-277648-9kxwkcbl	76	5	types	type	NNS
cord-277648-9kxwkcbl	76	6	contained	contain	VBD
cord-277648-9kxwkcbl	76	7	cells	cell	NNS
cord-277648-9kxwkcbl	76	8	from	from	IN
cord-277648-9kxwkcbl	76	9	ARDS	ARDS	NNP
cord-277648-9kxwkcbl	76	10	,	,	,
cord-277648-9kxwkcbl	76	11	non	non	NNP
cord-277648-9kxwkcbl	76	12	-	-	NNP
cord-277648-9kxwkcbl	76	13	ARDS	ARDS	NNP
cord-277648-9kxwkcbl	76	14	,	,	,
cord-277648-9kxwkcbl	76	15	and	and	CC
cord-277648-9kxwkcbl	76	16	control	control	NN
cord-277648-9kxwkcbl	76	17	donors	donor	NNS
cord-277648-9kxwkcbl	76	18	(	(	-LRB-
cord-277648-9kxwkcbl	76	19	Figure	figure	NN
cord-277648-9kxwkcbl	76	20	S1D	s1d	NN
cord-277648-9kxwkcbl	76	21	)	)	-RRB-
cord-277648-9kxwkcbl	76	22	.	.	.
cord-277648-9kxwkcbl	77	1	Cluster	cluster	NN
cord-277648-9kxwkcbl	77	2	16	16	CD
cord-277648-9kxwkcbl	78	1	(	(	-LRB-
cord-277648-9kxwkcbl	78	2	CD14+/CD3D+/IGHG4	CD14+/CD3D+/IGHG4	NNP
cord-277648-9kxwkcbl	78	3	+	+	CD
cord-277648-9kxwkcbl	78	4	)	)	-RRB-
cord-277648-9kxwkcbl	78	5	was	be	VBD
cord-277648-9kxwkcbl	78	6	annotated	annotate	VBN
cord-277648-9kxwkcbl	78	7	as	as	IN
cord-277648-9kxwkcbl	78	8	probable	probable	JJ
cord-277648-9kxwkcbl	78	9	doublets	doublet	NNS
cord-277648-9kxwkcbl	78	10	using	use	VBG
cord-277648-9kxwkcbl	78	11	the	the	DT
cord-277648-9kxwkcbl	78	12	marker	marker	NN
cord-277648-9kxwkcbl	78	13	gene	gene	NN
cord-277648-9kxwkcbl	78	14	panel	panel	NN
cord-277648-9kxwkcbl	78	15	shown	show	VBN
cord-277648-9kxwkcbl	78	16	in	in	IN
cord-277648-9kxwkcbl	78	17	Figure	figure	NN
cord-277648-9kxwkcbl	78	18	S1F	s1f	CD
cord-277648-9kxwkcbl	78	19	.	.	.
cord-277648-9kxwkcbl	79	1	Analyzing	analyze	VBG
cord-277648-9kxwkcbl	79	2	PBMC	PBMC	NNP
cord-277648-9kxwkcbl	79	3	compositional	compositional	JJ
cord-277648-9kxwkcbl	79	4	changes	change	NNS
cord-277648-9kxwkcbl	79	5	across	across	IN
cord-277648-9kxwkcbl	79	6	severity	severity	NN
cord-277648-9kxwkcbl	79	7	categories	category	NNS
cord-277648-9kxwkcbl	79	8	using	use	VBG
cord-277648-9kxwkcbl	79	9	z	z	VB
cord-277648-9kxwkcbl	79	10	-	-	HYPH
cord-277648-9kxwkcbl	79	11	scored	score	VBN
cord-277648-9kxwkcbl	79	12	percentages	percentage	NNS
cord-277648-9kxwkcbl	79	13	as	as	IN
cord-277648-9kxwkcbl	79	14	described	describe	VBN
cord-277648-9kxwkcbl	79	15	above	above	RB
cord-277648-9kxwkcbl	79	16	,	,	,
cord-277648-9kxwkcbl	79	17	we	-PRON-	PRP
cord-277648-9kxwkcbl	79	18	observed	observe	VBD
cord-277648-9kxwkcbl	79	19	trends	trend	NNS
cord-277648-9kxwkcbl	79	20	indicating	indicate	VBG
cord-277648-9kxwkcbl	79	21	a	a	DT
cord-277648-9kxwkcbl	79	22	decrease	decrease	NN
cord-277648-9kxwkcbl	79	23	in	in	IN
cord-277648-9kxwkcbl	79	24	erythrocyte	erythrocyte	NN
cord-277648-9kxwkcbl	79	25	and	and	CC
cord-277648-9kxwkcbl	79	26	CD8	CD8	NNP
cord-277648-9kxwkcbl	79	27	+	+	CC
cord-277648-9kxwkcbl	79	28	effector	effector	NN
cord-277648-9kxwkcbl	79	29	memory	memory	NN
cord-277648-9kxwkcbl	79	30	T	T	NNP
cord-277648-9kxwkcbl	79	31	cell	cell	NN
cord-277648-9kxwkcbl	79	32	percentages	percentage	NNS
cord-277648-9kxwkcbl	79	33	as	as	RB
cord-277648-9kxwkcbl	79	34	well	well	RB
cord-277648-9kxwkcbl	79	35	as	as	IN
cord-277648-9kxwkcbl	79	36	an	an	DT
cord-277648-9kxwkcbl	79	37	expansion	expansion	NN
cord-277648-9kxwkcbl	79	38	of	of	IN
cord-277648-9kxwkcbl	79	39	plasma	plasma	NN
cord-277648-9kxwkcbl	79	40	cells	cell	NNS
cord-277648-9kxwkcbl	79	41	and	and	CC
cord-277648-9kxwkcbl	79	42	proliferating	proliferate	VBG
cord-277648-9kxwkcbl	79	43	plasma	plasma	NN
cord-277648-9kxwkcbl	79	44	cells	cell	NNS
cord-277648-9kxwkcbl	79	45	in	in	IN
cord-277648-9kxwkcbl	79	46	both	both	CC
cord-277648-9kxwkcbl	79	47	ARDS	ARDS	NNP
cord-277648-9kxwkcbl	79	48	and	and	CC
cord-277648-9kxwkcbl	79	49	non	non	NNP
cord-277648-9kxwkcbl	79	50	-	-	JJ
cord-277648-9kxwkcbl	79	51	ARDS	ARDS	NNP
cord-277648-9kxwkcbl	79	52	patients	patient	NNS
cord-277648-9kxwkcbl	79	53	compared	compare	VBN
cord-277648-9kxwkcbl	79	54	to	to	TO
cord-277648-9kxwkcbl	79	55	control	control	VB
cord-277648-9kxwkcbl	79	56	donors	donor	NNS
cord-277648-9kxwkcbl	79	57	.	.	.
cord-277648-9kxwkcbl	80	1	To	to	TO
cord-277648-9kxwkcbl	80	2	examine	examine	VB
cord-277648-9kxwkcbl	80	3	the	the	DT
cord-277648-9kxwkcbl	80	4	population	population	NN
cord-277648-9kxwkcbl	80	5	of	of	IN
cord-277648-9kxwkcbl	80	6	NK	NK	NNP
cord-277648-9kxwkcbl	80	7	and	and	CC
cord-277648-9kxwkcbl	80	8	T	T	NNP
cord-277648-9kxwkcbl	80	9	cells	cell	NNS
cord-277648-9kxwkcbl	80	10	in	in	IN
cord-277648-9kxwkcbl	80	11	the	the	DT
cord-277648-9kxwkcbl	80	12	BALF	BALF	NNP
cord-277648-9kxwkcbl	80	13	at	at	IN
cord-277648-9kxwkcbl	80	14	finer	fine	JJR
cord-277648-9kxwkcbl	80	15	resolution	resolution	NN
cord-277648-9kxwkcbl	80	16	,	,	,
cord-277648-9kxwkcbl	80	17	we	-PRON-	PRP
cord-277648-9kxwkcbl	80	18	performed	perform	VBD
cord-277648-9kxwkcbl	80	19	iterative	iterative	JJ
cord-277648-9kxwkcbl	80	20	data	data	NN
cord-277648-9kxwkcbl	80	21	integration	integration	NN
cord-277648-9kxwkcbl	80	22	on	on	IN
cord-277648-9kxwkcbl	80	23	the	the	DT
cord-277648-9kxwkcbl	80	24	"	"	``
cord-277648-9kxwkcbl	80	25	NK	NK	NNP
cord-277648-9kxwkcbl	80	26	"	"	''
cord-277648-9kxwkcbl	80	27	,	,	,
cord-277648-9kxwkcbl	80	28	"	"	``
cord-277648-9kxwkcbl	80	29	Mixed	mixed	JJ
cord-277648-9kxwkcbl	80	30	T	t	NN
cord-277648-9kxwkcbl	80	31	"	"	''
cord-277648-9kxwkcbl	80	32	,	,	,
cord-277648-9kxwkcbl	80	33	and	and	CC
cord-277648-9kxwkcbl	80	34	"	"	``
cord-277648-9kxwkcbl	80	35	Proliferating	proliferate	VBG
cord-277648-9kxwkcbl	80	36	T	t	NN
cord-277648-9kxwkcbl	80	37	"	"	''
cord-277648-9kxwkcbl	80	38	populations	population	NNS
cord-277648-9kxwkcbl	80	39	,	,	,
cord-277648-9kxwkcbl	80	40	using	use	VBG
cord-277648-9kxwkcbl	80	41	5	5	CD
cord-277648-9kxwkcbl	80	42	severe	severe	JJ
cord-277648-9kxwkcbl	80	43	donors	donor	NNS
cord-277648-9kxwkcbl	80	44	,	,	,
cord-277648-9kxwkcbl	80	45	3	3	CD
cord-277648-9kxwkcbl	80	46	moderate	moderate	JJ
cord-277648-9kxwkcbl	80	47	donors	donor	NNS
cord-277648-9kxwkcbl	80	48	,	,	,
cord-277648-9kxwkcbl	80	49	and	and	CC
cord-277648-9kxwkcbl	80	50	3	3	CD
cord-277648-9kxwkcbl	80	51	healthy	healthy	JJ
cord-277648-9kxwkcbl	80	52	control	control	NN
cord-277648-9kxwkcbl	80	53	donors	donor	NNS
cord-277648-9kxwkcbl	80	54	.	.	.
cord-277648-9kxwkcbl	81	1	Severe	severe	JJ
cord-277648-9kxwkcbl	81	2	donor	donor	NN
cord-277648-9kxwkcbl	81	3	S3	s3	NN
cord-277648-9kxwkcbl	81	4	and	and	CC
cord-277648-9kxwkcbl	81	5	healthy	healthy	JJ
cord-277648-9kxwkcbl	81	6	control	control	NN
cord-277648-9kxwkcbl	81	7	donor	donor	NN
cord-277648-9kxwkcbl	81	8	HC2	HC2	NNP
cord-277648-9kxwkcbl	81	9	were	be	VBD
cord-277648-9kxwkcbl	81	10	omitted	omit	VBN
cord-277648-9kxwkcbl	81	11	as	as	IN
cord-277648-9kxwkcbl	81	12	a	a	DT
cord-277648-9kxwkcbl	81	13	consequence	consequence	NN
cord-277648-9kxwkcbl	81	14	of	of	IN
cord-277648-9kxwkcbl	81	15	having	have	VBG
cord-277648-9kxwkcbl	81	16	too	too	RB
cord-277648-9kxwkcbl	81	17	few	few	JJ
cord-277648-9kxwkcbl	81	18	NK	NK	NNP
cord-277648-9kxwkcbl	81	19	and	and	CC
cord-277648-9kxwkcbl	81	20	T	t	NN
cord-277648-9kxwkcbl	81	21	cells	cell	NNS
cord-277648-9kxwkcbl	81	22	to	to	TO
cord-277648-9kxwkcbl	81	23	allow	allow	VB
cord-277648-9kxwkcbl	81	24	integration	integration	NN
cord-277648-9kxwkcbl	81	25	and	and	CC
cord-277648-9kxwkcbl	81	26	alignment	alignment	NN
cord-277648-9kxwkcbl	81	27	.	.	.
cord-277648-9kxwkcbl	82	1	After	after	IN
cord-277648-9kxwkcbl	82	2	reintegration	reintegration	NN
cord-277648-9kxwkcbl	82	3	,	,	,
cord-277648-9kxwkcbl	82	4	a	a	DT
cord-277648-9kxwkcbl	82	5	total	total	NN
cord-277648-9kxwkcbl	82	6	of	of	IN
cord-277648-9kxwkcbl	82	7	8,832	8,832	CD
cord-277648-9kxwkcbl	82	8	NK	NK	NNP
cord-277648-9kxwkcbl	82	9	and	and	CC
cord-277648-9kxwkcbl	82	10	T	t	NN
cord-277648-9kxwkcbl	82	11	cells	cell	NNS
cord-277648-9kxwkcbl	82	12	were	be	VBD
cord-277648-9kxwkcbl	82	13	visualized	visualize	VBN
cord-277648-9kxwkcbl	82	14	via	via	IN
cord-277648-9kxwkcbl	82	15	UMAP	UMAP	NNP
cord-277648-9kxwkcbl	82	16	(	(	-LRB-
cord-277648-9kxwkcbl	82	17	Figure	figure	NN
cord-277648-9kxwkcbl	82	18	1C	1c	NN
cord-277648-9kxwkcbl	82	19	)	)	-RRB-
cord-277648-9kxwkcbl	82	20	.	.	.
cord-277648-9kxwkcbl	83	1	A	a	DT
cord-277648-9kxwkcbl	83	2	total	total	NN
cord-277648-9kxwkcbl	83	3	of	of	IN
cord-277648-9kxwkcbl	83	4	14	14	CD
cord-277648-9kxwkcbl	83	5	clusters	cluster	NNS
cord-277648-9kxwkcbl	83	6	were	be	VBD
cord-277648-9kxwkcbl	83	7	identified	identify	VBN
cord-277648-9kxwkcbl	83	8	,	,	,
cord-277648-9kxwkcbl	83	9	which	which	WDT
cord-277648-9kxwkcbl	83	10	were	be	VBD
cord-277648-9kxwkcbl	83	11	annotated	annotate	VBN
cord-277648-9kxwkcbl	83	12	according	accord	VBG
cord-277648-9kxwkcbl	83	13	to	to	IN
cord-277648-9kxwkcbl	83	14	8	8	CD
cord-277648-9kxwkcbl	83	15	distinct	distinct	JJ
cord-277648-9kxwkcbl	83	16	cell	cell	NN
cord-277648-9kxwkcbl	83	17	type	type	NN
cord-277648-9kxwkcbl	83	18	labels	label	NNS
cord-277648-9kxwkcbl	83	19	with	with	IN
cord-277648-9kxwkcbl	83	20	additional	additional	JJ
cord-277648-9kxwkcbl	83	21	cluster	cluster	NN
cord-277648-9kxwkcbl	83	22	13	13	CD
cord-277648-9kxwkcbl	83	23	labeled	label	VBN
cord-277648-9kxwkcbl	83	24	as	as	IN
cord-277648-9kxwkcbl	83	25	"	"	``
cord-277648-9kxwkcbl	83	26	uncertain	uncertain	JJ
cord-277648-9kxwkcbl	83	27	"	"	''
cord-277648-9kxwkcbl	83	28	and	and	CC
cord-277648-9kxwkcbl	83	29	clusters	cluster	NNS
cord-277648-9kxwkcbl	83	30	6	6	CD
cord-277648-9kxwkcbl	83	31	(	(	-LRB-
cord-277648-9kxwkcbl	83	32	CD3D+/CD68	cd3d+/cd68	NN
cord-277648-9kxwkcbl	83	33	+	+	SYM
cord-277648-9kxwkcbl	83	34	)	)	-RRB-
cord-277648-9kxwkcbl	83	35	and	and	CC
cord-277648-9kxwkcbl	83	36	12	12	CD
cord-277648-9kxwkcbl	83	37	(	(	-LRB-
cord-277648-9kxwkcbl	83	38	CD3D+/FCGR3B+	cd3d+/fcgr3b+	NN
cord-277648-9kxwkcbl	83	39	)	)	-RRB-
cord-277648-9kxwkcbl	83	40	classified	classify	VBN
cord-277648-9kxwkcbl	83	41	as	as	IN
cord-277648-9kxwkcbl	83	42	probable	probable	JJ
cord-277648-9kxwkcbl	83	43	doublets	doublet	NNS
cord-277648-9kxwkcbl	83	44	using	use	VBG
cord-277648-9kxwkcbl	83	45	the	the	DT
cord-277648-9kxwkcbl	83	46	marker	marker	NN
cord-277648-9kxwkcbl	83	47	gene	gene	NN
cord-277648-9kxwkcbl	83	48	panel	panel	NN
cord-277648-9kxwkcbl	83	49	shown	show	VBN
cord-277648-9kxwkcbl	83	50	in	in	IN
cord-277648-9kxwkcbl	83	51	Figure	figure	NN
cord-277648-9kxwkcbl	83	52	S1I	s1i	NN
cord-277648-9kxwkcbl	83	53	)	)	-RRB-
cord-277648-9kxwkcbl	83	54	.	.	.
cord-277648-9kxwkcbl	84	1	Analyzing	analyze	VBG
cord-277648-9kxwkcbl	84	2	NK	NK	NNP
cord-277648-9kxwkcbl	84	3	and	and	CC
cord-277648-9kxwkcbl	84	4	T	T	NNP
cord-277648-9kxwkcbl	84	5	cell	cell	NN
cord-277648-9kxwkcbl	84	6	compositional	compositional	JJ
cord-277648-9kxwkcbl	84	7	changes	change	NNS
cord-277648-9kxwkcbl	84	8	across	across	IN
cord-277648-9kxwkcbl	84	9	severity	severity	NN
cord-277648-9kxwkcbl	84	10	categories	category	NNS
cord-277648-9kxwkcbl	84	11	,	,	,
cord-277648-9kxwkcbl	84	12	we	-PRON-	PRP
cord-277648-9kxwkcbl	84	13	observed	observe	VBD
cord-277648-9kxwkcbl	84	14	trends	trend	NNS
cord-277648-9kxwkcbl	84	15	indicating	indicate	VBG
cord-277648-9kxwkcbl	84	16	expansion	expansion	NN
cord-277648-9kxwkcbl	84	17	of	of	IN
cord-277648-9kxwkcbl	84	18	CD4	CD4	NNP
cord-277648-9kxwkcbl	84	19	+	+	CC
cord-277648-9kxwkcbl	84	20	naive	naive	JJ
cord-277648-9kxwkcbl	84	21	T	T	NNP
cord-277648-9kxwkcbl	84	22	and	and	CC
cord-277648-9kxwkcbl	84	23	CD4	CD4	NNP
cord-277648-9kxwkcbl	84	24	+	+	CC
cord-277648-9kxwkcbl	84	25	effector	effector	VB
cord-277648-9kxwkcbl	84	26	Treg	Treg	NNP
cord-277648-9kxwkcbl	84	27	cells	cell	NNS
cord-277648-9kxwkcbl	84	28	in	in	IN
cord-277648-9kxwkcbl	84	29	moderate	moderate	JJ
cord-277648-9kxwkcbl	84	30	donors	donor	NNS
cord-277648-9kxwkcbl	84	31	compared	compare	VBN
cord-277648-9kxwkcbl	84	32	to	to	IN
cord-277648-9kxwkcbl	84	33	severe	severe	JJ
cord-277648-9kxwkcbl	84	34	and	and	CC
cord-277648-9kxwkcbl	84	35	control	control	NN
cord-277648-9kxwkcbl	84	36	donors	donor	NNS
cord-277648-9kxwkcbl	84	37	.	.	.
cord-277648-9kxwkcbl	85	1	The	the	DT
cord-277648-9kxwkcbl	85	2	distinctive	distinctive	JJ
cord-277648-9kxwkcbl	85	3	heterogeneity	heterogeneity	NN
cord-277648-9kxwkcbl	85	4	observed	observe	VBN
cord-277648-9kxwkcbl	85	5	in	in	IN
cord-277648-9kxwkcbl	85	6	mononuclear	mononuclear	JJ
cord-277648-9kxwkcbl	85	7	phagocytes	phagocyte	NNS
cord-277648-9kxwkcbl	85	8	(	(	-LRB-
cord-277648-9kxwkcbl	85	9	MPs	MPs	NNP
cord-277648-9kxwkcbl	85	10	)	)	-RRB-
cord-277648-9kxwkcbl	85	11	of	of	IN
cord-277648-9kxwkcbl	85	12	the	the	DT
cord-277648-9kxwkcbl	85	13	BALF	BALF	NNP
cord-277648-9kxwkcbl	85	14	seen	see	VBN
cord-277648-9kxwkcbl	85	15	in	in	IN
cord-277648-9kxwkcbl	85	16	Figure	Figure	NNP
cord-277648-9kxwkcbl	85	17	1A	1a	NN
cord-277648-9kxwkcbl	85	18	led	lead	VBD
cord-277648-9kxwkcbl	85	19	us	-PRON-	PRP
cord-277648-9kxwkcbl	85	20	to	to	TO
cord-277648-9kxwkcbl	85	21	address	address	VB
cord-277648-9kxwkcbl	85	22	severity	severity	NN
cord-277648-9kxwkcbl	85	23	-	-	HYPH
cord-277648-9kxwkcbl	85	24	specific	specific	JJ
cord-277648-9kxwkcbl	85	25	changes	change	NNS
cord-277648-9kxwkcbl	85	26	in	in	IN
cord-277648-9kxwkcbl	85	27	individual	individual	JJ
cord-277648-9kxwkcbl	85	28	MP	MP	NNP
cord-277648-9kxwkcbl	85	29	populations	population	NNS
cord-277648-9kxwkcbl	85	30	.	.	.
cord-277648-9kxwkcbl	86	1	We	-PRON-	PRP
cord-277648-9kxwkcbl	86	2	again	again	RB
cord-277648-9kxwkcbl	86	3	performed	perform	VBD
cord-277648-9kxwkcbl	86	4	iterative	iterative	JJ
cord-277648-9kxwkcbl	86	5	data	data	NN
cord-277648-9kxwkcbl	86	6	integration	integration	NN
cord-277648-9kxwkcbl	86	7	on	on	IN
cord-277648-9kxwkcbl	86	8	19	19	CD
cord-277648-9kxwkcbl	86	9	clusters	cluster	NNS
cord-277648-9kxwkcbl	86	10	identified	identify	VBN
cord-277648-9kxwkcbl	86	11	as	as	IN
cord-277648-9kxwkcbl	86	12	MPs	mp	NNS
cord-277648-9kxwkcbl	86	13	in	in	IN
cord-277648-9kxwkcbl	86	14	the	the	DT
cord-277648-9kxwkcbl	86	15	original	original	JJ
cord-277648-9kxwkcbl	86	16	BALF	BALF	NNP
cord-277648-9kxwkcbl	86	17	dataset	dataset	NN
cord-277648-9kxwkcbl	86	18	(	(	-LRB-
cord-277648-9kxwkcbl	86	19	Figure	figure	NN
cord-277648-9kxwkcbl	86	20	1A	1a	NN
cord-277648-9kxwkcbl	86	21	)	)	-RRB-
cord-277648-9kxwkcbl	86	22	.	.	.
cord-277648-9kxwkcbl	87	1	Following	follow	VBG
cord-277648-9kxwkcbl	87	2	iterative	iterative	JJ
cord-277648-9kxwkcbl	87	3	data	data	NN
cord-277648-9kxwkcbl	87	4	integration	integration	NN
cord-277648-9kxwkcbl	87	5	using	use	VBG
cord-277648-9kxwkcbl	87	6	6	6	CD
cord-277648-9kxwkcbl	87	7	severe	severe	JJ
cord-277648-9kxwkcbl	87	8	donors	donor	NNS
cord-277648-9kxwkcbl	87	9	,	,	,
cord-277648-9kxwkcbl	87	10	3	3	CD
cord-277648-9kxwkcbl	87	11	moderate	moderate	JJ
cord-277648-9kxwkcbl	87	12	donors	donor	NNS
cord-277648-9kxwkcbl	87	13	,	,	,
cord-277648-9kxwkcbl	87	14	and	and	CC
cord-277648-9kxwkcbl	87	15	4	4	CD
cord-277648-9kxwkcbl	87	16	healthy	healthy	JJ
cord-277648-9kxwkcbl	87	17	controls	control	NNS
cord-277648-9kxwkcbl	87	18	,	,	,
cord-277648-9kxwkcbl	87	19	a	a	DT
cord-277648-9kxwkcbl	87	20	total	total	NN
cord-277648-9kxwkcbl	87	21	of	of	IN
cord-277648-9kxwkcbl	87	22	50,146	50,146	CD
cord-277648-9kxwkcbl	87	23	MP	MP	NNP
cord-277648-9kxwkcbl	87	24	cells	cell	NNS
cord-277648-9kxwkcbl	87	25	were	be	VBD
cord-277648-9kxwkcbl	87	26	visualized	visualize	VBN
cord-277648-9kxwkcbl	87	27	by	by	IN
cord-277648-9kxwkcbl	87	28	UMAP	UMAP	NNP
cord-277648-9kxwkcbl	87	29	(	(	-LRB-
cord-277648-9kxwkcbl	87	30	Figure	figure	NN
cord-277648-9kxwkcbl	87	31	1D	1d	CD
cord-277648-9kxwkcbl	87	32	)	)	-RRB-
cord-277648-9kxwkcbl	87	33	.	.	.
cord-277648-9kxwkcbl	88	1	The	the	DT
cord-277648-9kxwkcbl	88	2	16	16	CD
cord-277648-9kxwkcbl	88	3	MP	MP	NNP
cord-277648-9kxwkcbl	88	4	clusters	cluster	NNS
cord-277648-9kxwkcbl	88	5	were	be	VBD
cord-277648-9kxwkcbl	88	6	left	leave	VBN
cord-277648-9kxwkcbl	88	7	unannotated	unannotated	JJ
cord-277648-9kxwkcbl	88	8	in	in	IN
cord-277648-9kxwkcbl	88	9	further	further	JJ
cord-277648-9kxwkcbl	88	10	analysis	analysis	NN
cord-277648-9kxwkcbl	88	11	.	.	.
cord-277648-9kxwkcbl	89	1	The	the	DT
cord-277648-9kxwkcbl	89	2	clusters	cluster	NNS
cord-277648-9kxwkcbl	89	3	were	be	VBD
cord-277648-9kxwkcbl	89	4	evaluated	evaluate	VBN
cord-277648-9kxwkcbl	89	5	using	use	VBG
cord-277648-9kxwkcbl	89	6	a	a	DT
cord-277648-9kxwkcbl	89	7	panel	panel	NN
cord-277648-9kxwkcbl	89	8	of	of	IN
cord-277648-9kxwkcbl	89	9	BALF	BALF	NNP
cord-277648-9kxwkcbl	89	10	marker	marker	NN
cord-277648-9kxwkcbl	89	11	genes	gene	NNS
cord-277648-9kxwkcbl	89	12	to	to	TO
cord-277648-9kxwkcbl	89	13	identify	identify	VB
cord-277648-9kxwkcbl	89	14	probable	probable	JJ
cord-277648-9kxwkcbl	89	15	doublets	doublet	NNS
cord-277648-9kxwkcbl	89	16	(	(	-LRB-
cord-277648-9kxwkcbl	89	17	Figure	Figure	NNP
cord-277648-9kxwkcbl	89	18	S1L	s1l	NN
cord-277648-9kxwkcbl	89	19	)	)	-RRB-
cord-277648-9kxwkcbl	89	20	,	,	,
cord-277648-9kxwkcbl	89	21	and	and	CC
cord-277648-9kxwkcbl	89	22	clusters	cluster	NNS
cord-277648-9kxwkcbl	89	23	12	12	CD
cord-277648-9kxwkcbl	89	24	(	(	-LRB-
cord-277648-9kxwkcbl	89	25	CD68+/CD3D+	CD68+/CD3D+	NNS
cord-277648-9kxwkcbl	89	26	)	)	-RRB-
cord-277648-9kxwkcbl	89	27	and	and	CC
cord-277648-9kxwkcbl	89	28	16	16	CD
cord-277648-9kxwkcbl	89	29	(	(	-LRB-
cord-277648-9kxwkcbl	89	30	CD68+/IGHG4	CD68+/IGHG4	NNP
cord-277648-9kxwkcbl	89	31	+	+	SYM
cord-277648-9kxwkcbl	89	32	)	)	-RRB-
cord-277648-9kxwkcbl	89	33	were	be	VBD
cord-277648-9kxwkcbl	89	34	classified	classify	VBN
cord-277648-9kxwkcbl	89	35	as	as	IN
cord-277648-9kxwkcbl	89	36	such	such	JJ
cord-277648-9kxwkcbl	89	37	.	.	.
cord-277648-9kxwkcbl	90	1	Analysis	analysis	NN
cord-277648-9kxwkcbl	90	2	of	of	IN
cord-277648-9kxwkcbl	90	3	compositional	compositional	JJ
cord-277648-9kxwkcbl	90	4	changes	change	NNS
cord-277648-9kxwkcbl	90	5	of	of	IN
cord-277648-9kxwkcbl	90	6	MP	MP	NNP
cord-277648-9kxwkcbl	90	7	clusters	cluster	NNS
cord-277648-9kxwkcbl	90	8	across	across	IN
cord-277648-9kxwkcbl	90	9	disease	disease	NN
cord-277648-9kxwkcbl	90	10	categories	category	NNS
cord-277648-9kxwkcbl	90	11	showed	show	VBD
cord-277648-9kxwkcbl	90	12	more	more	RBR
cord-277648-9kxwkcbl	90	13	pronounced	pronounce	VBN
cord-277648-9kxwkcbl	90	14	compositional	compositional	JJ
cord-277648-9kxwkcbl	90	15	changes	change	NNS
cord-277648-9kxwkcbl	90	16	than	than	IN
cord-277648-9kxwkcbl	90	17	we	-PRON-	PRP
cord-277648-9kxwkcbl	90	18	observed	observe	VBD
cord-277648-9kxwkcbl	90	19	in	in	IN
cord-277648-9kxwkcbl	90	20	the	the	DT
cord-277648-9kxwkcbl	90	21	BALF	BALF	NNP
cord-277648-9kxwkcbl	90	22	in	in	IN
cord-277648-9kxwkcbl	90	23	general	general	NN
cord-277648-9kxwkcbl	90	24	.	.	.
cord-277648-9kxwkcbl	91	1	Clusters	cluster	NNS
cord-277648-9kxwkcbl	91	2	0	0	CD
cord-277648-9kxwkcbl	91	3	,	,	,
cord-277648-9kxwkcbl	91	4	1	1	CD
cord-277648-9kxwkcbl	91	5	,	,	,
cord-277648-9kxwkcbl	91	6	and	and	CC
cord-277648-9kxwkcbl	91	7	6	6	CD
cord-277648-9kxwkcbl	91	8	(	(	-LRB-
cord-277648-9kxwkcbl	91	9	expressing	express	VBG
cord-277648-9kxwkcbl	91	10	chemokines	chemokine	NNS
cord-277648-9kxwkcbl	91	11	CCL2	CCL2	NNP
cord-277648-9kxwkcbl	91	12	,	,	,
cord-277648-9kxwkcbl	91	13	CCL3	CCL3	NNP
cord-277648-9kxwkcbl	91	14	,	,	,
cord-277648-9kxwkcbl	91	15	CCL8	CCL8	NNP
cord-277648-9kxwkcbl	91	16	as	as	RB
cord-277648-9kxwkcbl	91	17	well	well	RB
cord-277648-9kxwkcbl	91	18	as	as	IN
cord-277648-9kxwkcbl	91	19	SPP1	SPP1	NNS
cord-277648-9kxwkcbl	91	20	)	)	-RRB-
cord-277648-9kxwkcbl	91	21	appear	appear	VBP
cord-277648-9kxwkcbl	91	22	to	to	TO
cord-277648-9kxwkcbl	91	23	be	be	VB
cord-277648-9kxwkcbl	91	24	expanded	expand	VBN
cord-277648-9kxwkcbl	91	25	in	in	IN
cord-277648-9kxwkcbl	91	26	severe	severe	JJ
cord-277648-9kxwkcbl	91	27	donors	donor	NNS
cord-277648-9kxwkcbl	91	28	compared	compare	VBN
cord-277648-9kxwkcbl	91	29	to	to	IN
cord-277648-9kxwkcbl	91	30	moderate	moderate	JJ
cord-277648-9kxwkcbl	91	31	and	and	CC
cord-277648-9kxwkcbl	91	32	control	control	VB
cord-277648-9kxwkcbl	91	33	donors	donor	NNS
cord-277648-9kxwkcbl	91	34	,	,	,
cord-277648-9kxwkcbl	91	35	while	while	IN
cord-277648-9kxwkcbl	91	36	clusters	cluster	NNS
cord-277648-9kxwkcbl	91	37	2	2	CD
cord-277648-9kxwkcbl	91	38	,	,	,
cord-277648-9kxwkcbl	91	39	3	3	CD
cord-277648-9kxwkcbl	91	40	,	,	,
cord-277648-9kxwkcbl	91	41	and	and	CC
cord-277648-9kxwkcbl	91	42	8	8	CD
cord-277648-9kxwkcbl	91	43	(	(	-LRB-
cord-277648-9kxwkcbl	91	44	expressing	express	VBG
cord-277648-9kxwkcbl	91	45	MRC1	MRC1	NNP
cord-277648-9kxwkcbl	91	46	,	,	,
cord-277648-9kxwkcbl	91	47	C1QA	c1qa	UH
cord-277648-9kxwkcbl	91	48	,	,	,
cord-277648-9kxwkcbl	91	49	and	and	CC
cord-277648-9kxwkcbl	91	50	FABP4	fabp4	NN
cord-277648-9kxwkcbl	91	51	)	)	-RRB-
cord-277648-9kxwkcbl	91	52	appear	appear	VBP
cord-277648-9kxwkcbl	91	53	to	to	TO
cord-277648-9kxwkcbl	91	54	be	be	VB
cord-277648-9kxwkcbl	91	55	expanded	expand	VBN
cord-277648-9kxwkcbl	91	56	in	in	IN
cord-277648-9kxwkcbl	91	57	control	control	NN
cord-277648-9kxwkcbl	91	58	donors	donor	NNS
cord-277648-9kxwkcbl	91	59	compared	compare	VBN
cord-277648-9kxwkcbl	91	60	to	to	IN
cord-277648-9kxwkcbl	91	61	moderate	moderate	JJ
cord-277648-9kxwkcbl	91	62	and	and	CC
cord-277648-9kxwkcbl	91	63	severe	severe	JJ
cord-277648-9kxwkcbl	91	64	donors	donor	NNS
cord-277648-9kxwkcbl	91	65	.	.	.
cord-277648-9kxwkcbl	92	1	Cluster	cluster	NN
cord-277648-9kxwkcbl	92	2	5	5	CD
cord-277648-9kxwkcbl	92	3	(	(	-LRB-
cord-277648-9kxwkcbl	92	4	expressing	express	VBG
cord-277648-9kxwkcbl	92	5	HLADQA1	HLADQA1	NNP
cord-277648-9kxwkcbl	92	6	and	and	CC
cord-277648-9kxwkcbl	92	7	HLADQA2	HLADQA2	NNP
cord-277648-9kxwkcbl	92	8	)	)	-RRB-
cord-277648-9kxwkcbl	92	9	appears	appear	VBZ
cord-277648-9kxwkcbl	92	10	to	to	TO
cord-277648-9kxwkcbl	92	11	be	be	VB
cord-277648-9kxwkcbl	92	12	uniquely	uniquely	RB
cord-277648-9kxwkcbl	92	13	expanded	expand	VBN
cord-277648-9kxwkcbl	92	14	in	in	IN
cord-277648-9kxwkcbl	92	15	moderate	moderate	JJ
cord-277648-9kxwkcbl	92	16	donors	donor	NNS
cord-277648-9kxwkcbl	92	17	compared	compare	VBN
cord-277648-9kxwkcbl	92	18	to	to	TO
cord-277648-9kxwkcbl	92	19	control	control	VB
cord-277648-9kxwkcbl	92	20	and	and	CC
cord-277648-9kxwkcbl	92	21	severe	severe	JJ
cord-277648-9kxwkcbl	92	22	donors	donor	NNS
cord-277648-9kxwkcbl	92	23	.	.	.
cord-277648-9kxwkcbl	93	1	Cellular	cellular	JJ
cord-277648-9kxwkcbl	93	2	markers	marker	NNS
cord-277648-9kxwkcbl	93	3	corresponding	correspond	VBG
cord-277648-9kxwkcbl	93	4	to	to	IN
cord-277648-9kxwkcbl	93	5	clinical	clinical	JJ
cord-277648-9kxwkcbl	93	6	categories	category	NNS
cord-277648-9kxwkcbl	93	7	of	of	IN
cord-277648-9kxwkcbl	93	8	COVID-19	covid-19	JJ
cord-277648-9kxwkcbl	93	9	disease	disease	NN
cord-277648-9kxwkcbl	93	10	severity	severity	NN
cord-277648-9kxwkcbl	93	11	have	have	VBP
cord-277648-9kxwkcbl	93	12	not	not	RB
cord-277648-9kxwkcbl	93	13	yet	yet	RB
cord-277648-9kxwkcbl	93	14	been	be	VBN
cord-277648-9kxwkcbl	93	15	rigorously	rigorously	RB
cord-277648-9kxwkcbl	93	16	characterized	characterize	VBN
cord-277648-9kxwkcbl	93	17	.	.	.
cord-277648-9kxwkcbl	94	1	Here	here	RB
cord-277648-9kxwkcbl	94	2	,	,	,
cord-277648-9kxwkcbl	94	3	we	-PRON-	PRP
cord-277648-9kxwkcbl	94	4	sought	seek	VBD
cord-277648-9kxwkcbl	94	5	to	to	TO
cord-277648-9kxwkcbl	94	6	leverage	leverage	VB
cord-277648-9kxwkcbl	94	7	transcriptional	transcriptional	JJ
cord-277648-9kxwkcbl	94	8	differences	difference	NNS
cord-277648-9kxwkcbl	94	9	across	across	IN
cord-277648-9kxwkcbl	94	10	severity	severity	NN
cord-277648-9kxwkcbl	94	11	strata	strata	NN
cord-277648-9kxwkcbl	94	12	to	to	TO
cord-277648-9kxwkcbl	94	13	identify	identify	VB
cord-277648-9kxwkcbl	94	14	surface	surface	NN
cord-277648-9kxwkcbl	94	15	-	-	HYPH
cord-277648-9kxwkcbl	94	16	bound	bind	VBN
cord-277648-9kxwkcbl	94	17	proteins	protein	NNS
cord-277648-9kxwkcbl	94	18	in	in	IN
cord-277648-9kxwkcbl	94	19	both	both	CC
cord-277648-9kxwkcbl	94	20	the	the	DT
cord-277648-9kxwkcbl	94	21	lung	lung	NN
cord-277648-9kxwkcbl	94	22	and	and	CC
cord-277648-9kxwkcbl	94	23	blood	blood	NN
cord-277648-9kxwkcbl	94	24	that	that	WDT
cord-277648-9kxwkcbl	94	25	could	could	MD
cord-277648-9kxwkcbl	94	26	be	be	VB
cord-277648-9kxwkcbl	94	27	used	use	VBN
cord-277648-9kxwkcbl	94	28	as	as	IN
cord-277648-9kxwkcbl	94	29	markers	marker	NNS
cord-277648-9kxwkcbl	94	30	for	for	IN
cord-277648-9kxwkcbl	94	31	immunophenotyping	immunophenotyping	NN
cord-277648-9kxwkcbl	94	32	.	.	.
cord-277648-9kxwkcbl	95	1	To	to	TO
cord-277648-9kxwkcbl	95	2	nominate	nominate	VB
cord-277648-9kxwkcbl	95	3	putative	putative	JJ
cord-277648-9kxwkcbl	95	4	cell	cell	NN
cord-277648-9kxwkcbl	95	5	surface	surface	NN
cord-277648-9kxwkcbl	95	6	markers	marker	NNS
cord-277648-9kxwkcbl	95	7	,	,	,
cord-277648-9kxwkcbl	95	8	we	-PRON-	PRP
cord-277648-9kxwkcbl	95	9	conducted	conduct	VBD
cord-277648-9kxwkcbl	95	10	differential	differential	JJ
cord-277648-9kxwkcbl	95	11	gene	gene	NN
cord-277648-9kxwkcbl	95	12	expression	expression	NN
cord-277648-9kxwkcbl	95	13	analysis	analysis	NN
cord-277648-9kxwkcbl	95	14	between	between	IN
cord-277648-9kxwkcbl	95	15	severe	severe	JJ
cord-277648-9kxwkcbl	95	16	and	and	CC
cord-277648-9kxwkcbl	95	17	moderate	moderate	JJ
cord-277648-9kxwkcbl	95	18	patient	patient	JJ
cord-277648-9kxwkcbl	95	19	groups	group	NNS
cord-277648-9kxwkcbl	95	20	for	for	IN
cord-277648-9kxwkcbl	95	21	lung	lung	NN
cord-277648-9kxwkcbl	95	22	(	(	-LRB-
cord-277648-9kxwkcbl	95	23	BALF	BALF	NNP
cord-277648-9kxwkcbl	95	24	)	)	-RRB-
cord-277648-9kxwkcbl	95	25	cells	cell	NNS
cord-277648-9kxwkcbl	95	26	and	and	CC
cord-277648-9kxwkcbl	95	27	between	between	IN
cord-277648-9kxwkcbl	95	28	ARDS	ARDS	NNP
cord-277648-9kxwkcbl	95	29	and	and	CC
cord-277648-9kxwkcbl	95	30	non	non	NNP
cord-277648-9kxwkcbl	95	31	-	-	JJ
cord-277648-9kxwkcbl	95	32	ARDS	ards	JJ
cord-277648-9kxwkcbl	95	33	patient	patient	NN
cord-277648-9kxwkcbl	95	34	groups	group	NNS
cord-277648-9kxwkcbl	95	35	for	for	IN
cord-277648-9kxwkcbl	95	36	blood	blood	NN
cord-277648-9kxwkcbl	95	37	(	(	-LRB-
cord-277648-9kxwkcbl	95	38	PBMC	PBMC	NNP
cord-277648-9kxwkcbl	95	39	)	)	-RRB-
cord-277648-9kxwkcbl	95	40	cells	cell	NNS
cord-277648-9kxwkcbl	95	41	and	and	CC
cord-277648-9kxwkcbl	95	42	selected	select	VBN
cord-277648-9kxwkcbl	95	43	significant	significant	JJ
cord-277648-9kxwkcbl	95	44	differentially	differentially	RB
cord-277648-9kxwkcbl	95	45	expressed	express	VBN
cord-277648-9kxwkcbl	95	46	genes	gene	NNS
cord-277648-9kxwkcbl	95	47	(	(	-LRB-
cord-277648-9kxwkcbl	95	48	DEGs	DEGs	NNP
cord-277648-9kxwkcbl	95	49	)	)	-RRB-
cord-277648-9kxwkcbl	95	50	with	with	IN
cord-277648-9kxwkcbl	95	51	a	a	DT
cord-277648-9kxwkcbl	95	52	fold	fold	JJ
cord-277648-9kxwkcbl	95	53	change	change	NN
cord-277648-9kxwkcbl	95	54	(	(	-LRB-
cord-277648-9kxwkcbl	95	55	FC	FC	NNP
cord-277648-9kxwkcbl	95	56	)	)	-RRB-
cord-277648-9kxwkcbl	95	57	cutoff	cutoff	NN
cord-277648-9kxwkcbl	95	58	of	of	IN
cord-277648-9kxwkcbl	95	59	|log2FC>1|	|log2FC>1|	NNP
cord-277648-9kxwkcbl	95	60	.	.	.
cord-277648-9kxwkcbl	96	1	Figure	figure	NN
cord-277648-9kxwkcbl	96	2	2A	2a	CD
cord-277648-9kxwkcbl	96	3	shows	show	VBZ
cord-277648-9kxwkcbl	96	4	significantly	significantly	RB
cord-277648-9kxwkcbl	96	5	up	up	RB
cord-277648-9kxwkcbl	96	6	-	-	:
cord-277648-9kxwkcbl	96	7	and	and	CC
cord-277648-9kxwkcbl	96	8	downregulated	downregulate	VBD
cord-277648-9kxwkcbl	96	9	transcripts	transcript	NNS
cord-277648-9kxwkcbl	96	10	for	for	IN
cord-277648-9kxwkcbl	96	11	pDCs	pDCs	NNP
cord-277648-9kxwkcbl	96	12	in	in	IN
cord-277648-9kxwkcbl	96	13	the	the	DT
cord-277648-9kxwkcbl	96	14	BALF	BALF	NNP
cord-277648-9kxwkcbl	96	15	,	,	,
cord-277648-9kxwkcbl	96	16	one	one	CD
cord-277648-9kxwkcbl	96	17	of	of	IN
cord-277648-9kxwkcbl	96	18	17	17	CD
cord-277648-9kxwkcbl	96	19	lung	lung	NN
cord-277648-9kxwkcbl	96	20	cell	cell	NN
cord-277648-9kxwkcbl	96	21	types	type	NNS
cord-277648-9kxwkcbl	96	22	studied	study	VBD
cord-277648-9kxwkcbl	96	23	.	.	.
cord-277648-9kxwkcbl	97	1	From	from	IN
cord-277648-9kxwkcbl	97	2	the	the	DT
cord-277648-9kxwkcbl	97	3	large	large	JJ
cord-277648-9kxwkcbl	97	4	number	number	NN
cord-277648-9kxwkcbl	97	5	of	of	IN
cord-277648-9kxwkcbl	97	6	significant	significant	JJ
cord-277648-9kxwkcbl	97	7	DEGs	deg	NNS
cord-277648-9kxwkcbl	97	8	,	,	,
cord-277648-9kxwkcbl	97	9	we	-PRON-	PRP
cord-277648-9kxwkcbl	97	10	observed	observe	VBD
cord-277648-9kxwkcbl	97	11	the	the	DT
cord-277648-9kxwkcbl	97	12	upregulation	upregulation	NN
cord-277648-9kxwkcbl	97	13	of	of	IN
cord-277648-9kxwkcbl	97	14	AREG	AREG	NNP
cord-277648-9kxwkcbl	97	15	and	and	CC
cord-277648-9kxwkcbl	97	16	CD55	CD55	NNP
cord-277648-9kxwkcbl	97	17	,	,	,
cord-277648-9kxwkcbl	97	18	which	which	WDT
cord-277648-9kxwkcbl	97	19	were	be	VBD
cord-277648-9kxwkcbl	97	20	verified	verify	VBN
cord-277648-9kxwkcbl	97	21	as	as	IN
cord-277648-9kxwkcbl	97	22	cell	cell	NN
cord-277648-9kxwkcbl	97	23	surface	surface	NN
cord-277648-9kxwkcbl	97	24	protein	protein	NN
cord-277648-9kxwkcbl	97	25	-	-	HYPH
cord-277648-9kxwkcbl	97	26	coding	code	VBG
cord-277648-9kxwkcbl	97	27	genes	gene	NNS
cord-277648-9kxwkcbl	97	28	using	use	VBG
cord-277648-9kxwkcbl	97	29	the	the	DT
cord-277648-9kxwkcbl	97	30	Cell	Cell	NNP
cord-277648-9kxwkcbl	97	31	Surface	Surface	NNP
cord-277648-9kxwkcbl	97	32	Protein	Protein	NNP
cord-277648-9kxwkcbl	97	33	Atlas	Atlas	NNP
cord-277648-9kxwkcbl	97	34	[	[	-LRB-
cord-277648-9kxwkcbl	97	35	38	38	CD
cord-277648-9kxwkcbl	97	36	]	]	-RRB-
cord-277648-9kxwkcbl	97	37	.	.	.
cord-277648-9kxwkcbl	98	1	The	the	DT
cord-277648-9kxwkcbl	98	2	AREG	AREG	NNP
cord-277648-9kxwkcbl	98	3	and	and	CC
cord-277648-9kxwkcbl	98	4	CD55	CD55	NNP
cord-277648-9kxwkcbl	98	5	transcripts	transcript	NNS
cord-277648-9kxwkcbl	98	6	show	show	VBP
cord-277648-9kxwkcbl	98	7	robustly	robustly	RB
cord-277648-9kxwkcbl	98	8	increased	increase	VBD
cord-277648-9kxwkcbl	98	9	expression	expression	NN
cord-277648-9kxwkcbl	98	10	in	in	IN
cord-277648-9kxwkcbl	98	11	pDCs	pDCs	NNP
cord-277648-9kxwkcbl	98	12	in	in	IN
cord-277648-9kxwkcbl	98	13	severe	severe	JJ
cord-277648-9kxwkcbl	98	14	compared	compare	VBN
cord-277648-9kxwkcbl	98	15	to	to	IN
cord-277648-9kxwkcbl	98	16	moderate	moderate	JJ
cord-277648-9kxwkcbl	98	17	disease	disease	NN
cord-277648-9kxwkcbl	98	18	(	(	-LRB-
cord-277648-9kxwkcbl	98	19	Figure	figure	NN
cord-277648-9kxwkcbl	98	20	2B	2b	CD
cord-277648-9kxwkcbl	98	21	)	)	-RRB-
cord-277648-9kxwkcbl	98	22	and	and	CC
cord-277648-9kxwkcbl	98	23	compared	compare	VBN
cord-277648-9kxwkcbl	98	24	to	to	IN
cord-277648-9kxwkcbl	98	25	pDCs	pdcs	VB
cord-277648-9kxwkcbl	98	26	in	in	IN
cord-277648-9kxwkcbl	98	27	healthy	healthy	JJ
cord-277648-9kxwkcbl	98	28	control	control	NN
cord-277648-9kxwkcbl	98	29	subjects	subject	NNS
cord-277648-9kxwkcbl	98	30	(	(	-LRB-
cord-277648-9kxwkcbl	98	31	Figure	figure	NN
cord-277648-9kxwkcbl	98	32	S2A	s2a	NN
cord-277648-9kxwkcbl	98	33	)	)	-RRB-
cord-277648-9kxwkcbl	98	34	.	.	.
cord-277648-9kxwkcbl	99	1	We	-PRON-	PRP
cord-277648-9kxwkcbl	99	2	additionally	additionally	RB
cord-277648-9kxwkcbl	99	3	showed	show	VBD
cord-277648-9kxwkcbl	99	4	that	that	IN
cord-277648-9kxwkcbl	99	5	AREG	AREG	NNP
cord-277648-9kxwkcbl	99	6	and	and	CC
cord-277648-9kxwkcbl	99	7	CD55	CD55	NNP
cord-277648-9kxwkcbl	99	8	are	be	VBP
cord-277648-9kxwkcbl	99	9	not	not	RB
cord-277648-9kxwkcbl	99	10	upregulated	upregulate	VBN
cord-277648-9kxwkcbl	99	11	in	in	IN
cord-277648-9kxwkcbl	99	12	moderate	moderate	JJ
cord-277648-9kxwkcbl	99	13	disease	disease	NN
cord-277648-9kxwkcbl	99	14	compared	compare	VBN
cord-277648-9kxwkcbl	99	15	to	to	IN
cord-277648-9kxwkcbl	99	16	controls	control	NNS
cord-277648-9kxwkcbl	99	17	(	(	-LRB-
cord-277648-9kxwkcbl	99	18	Figure	figure	NN
cord-277648-9kxwkcbl	99	19	S2A	s2a	NN
cord-277648-9kxwkcbl	99	20	)	)	-RRB-
cord-277648-9kxwkcbl	99	21	.	.	.
cord-277648-9kxwkcbl	100	1	The	the	DT
cord-277648-9kxwkcbl	100	2	expression	expression	NN
cord-277648-9kxwkcbl	100	3	of	of	IN
cord-277648-9kxwkcbl	100	4	AREG	AREG	NNP
cord-277648-9kxwkcbl	100	5	and	and	CC
cord-277648-9kxwkcbl	100	6	CD55	CD55	NNP
cord-277648-9kxwkcbl	100	7	was	be	VBD
cord-277648-9kxwkcbl	100	8	cross	cross	NN
cord-277648-9kxwkcbl	100	9	-	-	VBN
cord-277648-9kxwkcbl	100	10	referenced	reference	VBN
cord-277648-9kxwkcbl	100	11	with	with	IN
cord-277648-9kxwkcbl	100	12	bulk	bulk	JJ
cord-277648-9kxwkcbl	100	13	RNA	RNA	NNP
cord-277648-9kxwkcbl	100	14	-	-	HYPH
cord-277648-9kxwkcbl	100	15	seq	seq	NNP
cord-277648-9kxwkcbl	100	16	blood	blood	NN
cord-277648-9kxwkcbl	100	17	data	datum	NNS
cord-277648-9kxwkcbl	100	18	from	from	IN
cord-277648-9kxwkcbl	100	19	the	the	DT
cord-277648-9kxwkcbl	100	20	human	human	JJ
cord-277648-9kxwkcbl	100	21	Immune	Immune	NNP
cord-277648-9kxwkcbl	100	22	Cell	Cell	NNP
cord-277648-9kxwkcbl	100	23	Atlas	Atlas	NNP
cord-277648-9kxwkcbl	100	24	(	(	-LRB-
cord-277648-9kxwkcbl	100	25	Figure	figure	NN
cord-277648-9kxwkcbl	100	26	S2C	S2C	NNP
cord-277648-9kxwkcbl	100	27	)	)	-RRB-
cord-277648-9kxwkcbl	100	28	,	,	,
cord-277648-9kxwkcbl	100	29	and	and	CC
cord-277648-9kxwkcbl	100	30	expression	expression	NN
cord-277648-9kxwkcbl	100	31	of	of	IN
cord-277648-9kxwkcbl	100	32	these	these	DT
cord-277648-9kxwkcbl	100	33	transcripts	transcript	NNS
cord-277648-9kxwkcbl	100	34	in	in	IN
cord-277648-9kxwkcbl	100	35	various	various	JJ
cord-277648-9kxwkcbl	100	36	subtypes	subtype	NNS
cord-277648-9kxwkcbl	100	37	of	of	IN
cord-277648-9kxwkcbl	100	38	DCs	dc	NNS
cord-277648-9kxwkcbl	100	39	was	be	VBD
cord-277648-9kxwkcbl	100	40	verified	verify	VBN
cord-277648-9kxwkcbl	100	41	[	[	-LRB-
cord-277648-9kxwkcbl	100	42	39	39	CD
cord-277648-9kxwkcbl	100	43	,	,	,
cord-277648-9kxwkcbl	100	44	40	40	CD
cord-277648-9kxwkcbl	100	45	]	]	-RRB-
cord-277648-9kxwkcbl	100	46	.	.	.
cord-277648-9kxwkcbl	101	1	Differential	differential	JJ
cord-277648-9kxwkcbl	101	2	expression	expression	NN
cord-277648-9kxwkcbl	101	3	of	of	IN
cord-277648-9kxwkcbl	101	4	transcripts	transcript	NNS
cord-277648-9kxwkcbl	101	5	coding	code	VBG
cord-277648-9kxwkcbl	101	6	for	for	IN
cord-277648-9kxwkcbl	101	7	cell	cell	NN
cord-277648-9kxwkcbl	101	8	surface	surface	NN
cord-277648-9kxwkcbl	101	9	proteins	protein	NNS
cord-277648-9kxwkcbl	101	10	was	be	VBD
cord-277648-9kxwkcbl	101	11	evaluated	evaluate	VBN
cord-277648-9kxwkcbl	101	12	for	for	IN
cord-277648-9kxwkcbl	101	13	every	every	DT
cord-277648-9kxwkcbl	101	14	cell	cell	NN
cord-277648-9kxwkcbl	101	15	type	type	NN
cord-277648-9kxwkcbl	101	16	in	in	IN
cord-277648-9kxwkcbl	101	17	the	the	DT
cord-277648-9kxwkcbl	101	18	BALF	BALF	NNP
cord-277648-9kxwkcbl	101	19	,	,	,
cord-277648-9kxwkcbl	101	20	resulting	result	VBG
cord-277648-9kxwkcbl	101	21	in	in	IN
cord-277648-9kxwkcbl	101	22	a	a	DT
cord-277648-9kxwkcbl	101	23	matrix	matrix	NN
cord-277648-9kxwkcbl	101	24	of	of	IN
cord-277648-9kxwkcbl	101	25	potential	potential	JJ
cord-277648-9kxwkcbl	101	26	severity	severity	NN
cord-277648-9kxwkcbl	101	27	-	-	HYPH
cord-277648-9kxwkcbl	101	28	specific	specific	JJ
cord-277648-9kxwkcbl	101	29	surface	surface	NN
cord-277648-9kxwkcbl	101	30	markers	marker	NNS
cord-277648-9kxwkcbl	101	31	for	for	IN
cord-277648-9kxwkcbl	101	32	each	each	DT
cord-277648-9kxwkcbl	101	33	cell	cell	NN
cord-277648-9kxwkcbl	101	34	type	type	NN
cord-277648-9kxwkcbl	101	35	(	(	-LRB-
cord-277648-9kxwkcbl	101	36	Figure	figure	NN
cord-277648-9kxwkcbl	101	37	2C	2c	NN
cord-277648-9kxwkcbl	101	38	)	)	-RRB-
cord-277648-9kxwkcbl	101	39	.	.	.
cord-277648-9kxwkcbl	102	1	Upregulation	Upregulation	NNP
cord-277648-9kxwkcbl	102	2	of	of	IN
cord-277648-9kxwkcbl	102	3	the	the	DT
cord-277648-9kxwkcbl	102	4	AREG	AREG	NNP
cord-277648-9kxwkcbl	102	5	gene	gene	NN
cord-277648-9kxwkcbl	102	6	was	be	VBD
cord-277648-9kxwkcbl	102	7	also	also	RB
cord-277648-9kxwkcbl	102	8	observed	observe	VBN
cord-277648-9kxwkcbl	102	9	in	in	IN
cord-277648-9kxwkcbl	102	10	myeloid	myeloid	JJ
cord-277648-9kxwkcbl	102	11	dendritic	dendritic	JJ
cord-277648-9kxwkcbl	102	12	cells	cell	NNS
cord-277648-9kxwkcbl	102	13	(	(	-LRB-
cord-277648-9kxwkcbl	102	14	mDCs	mDCs	NNP
cord-277648-9kxwkcbl	102	15	,	,	,
cord-277648-9kxwkcbl	102	16	also	also	RB
cord-277648-9kxwkcbl	102	17	known	know	VBN
cord-277648-9kxwkcbl	102	18	as	as	IN
cord-277648-9kxwkcbl	102	19	conventional	conventional	JJ
cord-277648-9kxwkcbl	102	20	dendritic	dendritic	JJ
cord-277648-9kxwkcbl	102	21	cells	cell	NNS
cord-277648-9kxwkcbl	102	22	)	)	-RRB-
cord-277648-9kxwkcbl	102	23	,	,	,
cord-277648-9kxwkcbl	102	24	indicating	indicate	VBG
cord-277648-9kxwkcbl	102	25	a	a	DT
cord-277648-9kxwkcbl	102	26	possible	possible	JJ
cord-277648-9kxwkcbl	102	27	conserved	conserve	VBN
cord-277648-9kxwkcbl	102	28	response	response	NN
cord-277648-9kxwkcbl	102	29	across	across	IN
cord-277648-9kxwkcbl	102	30	DC	DC	NNP
cord-277648-9kxwkcbl	102	31	subtypes	subtype	NNS
cord-277648-9kxwkcbl	102	32	.	.	.
cord-277648-9kxwkcbl	103	1	Extending	extend	VBG
cord-277648-9kxwkcbl	103	2	our	-PRON-	PRP$
cord-277648-9kxwkcbl	103	3	analysis	analysis	NN
cord-277648-9kxwkcbl	103	4	beyond	beyond	IN
cord-277648-9kxwkcbl	103	5	immune	immune	JJ
cord-277648-9kxwkcbl	103	6	cell	cell	NN
cord-277648-9kxwkcbl	103	7	types	type	NNS
cord-277648-9kxwkcbl	103	8	and	and	CC
cord-277648-9kxwkcbl	103	9	relaxing	relax	VBG
cord-277648-9kxwkcbl	103	10	the	the	DT
cord-277648-9kxwkcbl	103	11	stringency	stringency	NN
cord-277648-9kxwkcbl	103	12	cutoff	cutoff	NN
cord-277648-9kxwkcbl	103	13	of	of	IN
cord-277648-9kxwkcbl	103	14	|log2FC>1|	|log2FC>1|	NNP
cord-277648-9kxwkcbl	103	15	,	,	,
cord-277648-9kxwkcbl	103	16	we	-PRON-	PRP
cord-277648-9kxwkcbl	103	17	made	make	VBD
cord-277648-9kxwkcbl	103	18	the	the	DT
cord-277648-9kxwkcbl	103	19	interesting	interesting	JJ
cord-277648-9kxwkcbl	103	20	observation	observation	NN
cord-277648-9kxwkcbl	103	21	that	that	IN
cord-277648-9kxwkcbl	103	22	epithelial	epithelial	JJ
cord-277648-9kxwkcbl	103	23	(	(	-LRB-
cord-277648-9kxwkcbl	103	24	club	club	NN
cord-277648-9kxwkcbl	103	25	and	and	CC
cord-277648-9kxwkcbl	103	26	ciliated	ciliated	JJ
cord-277648-9kxwkcbl	103	27	)	)	-RRB-
cord-277648-9kxwkcbl	103	28	cells	cell	NNS
cord-277648-9kxwkcbl	103	29	demonstrate	demonstrate	VBP
cord-277648-9kxwkcbl	103	30	significant	significant	JJ
cord-277648-9kxwkcbl	103	31	upregulation	upregulation	NN
cord-277648-9kxwkcbl	103	32	of	of	IN
cord-277648-9kxwkcbl	103	33	ICAM1	ICAM1	NNP
cord-277648-9kxwkcbl	103	34	and	and	CC
cord-277648-9kxwkcbl	103	35	LDLR	LDLR	NNP
cord-277648-9kxwkcbl	103	36	,	,	,
cord-277648-9kxwkcbl	103	37	the	the	DT
cord-277648-9kxwkcbl	103	38	two	two	CD
cord-277648-9kxwkcbl	103	39	main	main	JJ
cord-277648-9kxwkcbl	103	40	entry	entry	NN
cord-277648-9kxwkcbl	103	41	receptors	receptor	NNS
cord-277648-9kxwkcbl	103	42	for	for	IN
cord-277648-9kxwkcbl	103	43	respiratory	respiratory	JJ
cord-277648-9kxwkcbl	103	44	rhinoviruses	rhinovirus	NNS
cord-277648-9kxwkcbl	103	45	.	.	.
cord-277648-9kxwkcbl	104	1	We	-PRON-	PRP
cord-277648-9kxwkcbl	104	2	confirmed	confirm	VBD
cord-277648-9kxwkcbl	104	3	that	that	IN
cord-277648-9kxwkcbl	104	4	markers	marker	NNS
cord-277648-9kxwkcbl	104	5	identified	identify	VBN
cord-277648-9kxwkcbl	104	6	as	as	IN
cord-277648-9kxwkcbl	104	7	differentially	differentially	RB
cord-277648-9kxwkcbl	104	8	regulated	regulate	VBN
cord-277648-9kxwkcbl	104	9	between	between	IN
cord-277648-9kxwkcbl	104	10	severe	severe	JJ
cord-277648-9kxwkcbl	104	11	and	and	CC
cord-277648-9kxwkcbl	104	12	moderate	moderate	JJ
cord-277648-9kxwkcbl	104	13	disease	disease	NN
cord-277648-9kxwkcbl	104	14	were	be	VBD
cord-277648-9kxwkcbl	104	15	not	not	RB
cord-277648-9kxwkcbl	104	16	differentially	differentially	RB
cord-277648-9kxwkcbl	104	17	regulated	regulate	VBN
cord-277648-9kxwkcbl	104	18	in	in	IN
cord-277648-9kxwkcbl	104	19	the	the	DT
cord-277648-9kxwkcbl	104	20	same	same	JJ
cord-277648-9kxwkcbl	104	21	direction	direction	NN
cord-277648-9kxwkcbl	104	22	between	between	IN
cord-277648-9kxwkcbl	104	23	moderate	moderate	JJ
cord-277648-9kxwkcbl	104	24	disease	disease	NN
cord-277648-9kxwkcbl	104	25	and	and	CC
cord-277648-9kxwkcbl	104	26	control	control	NN
cord-277648-9kxwkcbl	104	27	(	(	-LRB-
cord-277648-9kxwkcbl	104	28	Figure	Figure	NNP
cord-277648-9kxwkcbl	104	29	S2B	S2B	NNP
cord-277648-9kxwkcbl	104	30	)	)	-RRB-
cord-277648-9kxwkcbl	104	31	,	,	,
cord-277648-9kxwkcbl	104	32	with	with	IN
cord-277648-9kxwkcbl	104	33	the	the	DT
cord-277648-9kxwkcbl	104	34	exception	exception	NN
cord-277648-9kxwkcbl	104	35	of	of	IN
cord-277648-9kxwkcbl	104	36	HLADRA	HLADRA	NNP
cord-277648-9kxwkcbl	104	37	and	and	CC
cord-277648-9kxwkcbl	104	38	VAMP5	VAMP5	NNP
cord-277648-9kxwkcbl	104	39	on	on	IN
cord-277648-9kxwkcbl	104	40	MPs	MPs	NNPS
cord-277648-9kxwkcbl	104	41	and	and	CC
cord-277648-9kxwkcbl	104	42	CCR7	CCR7	NNP
cord-277648-9kxwkcbl	104	43	on	on	IN
cord-277648-9kxwkcbl	104	44	mDCs	mDCs	NNP
cord-277648-9kxwkcbl	104	45	,	,	,
cord-277648-9kxwkcbl	104	46	indicating	indicate	VBG
cord-277648-9kxwkcbl	104	47	that	that	IN
cord-277648-9kxwkcbl	104	48	all	all	DT
cord-277648-9kxwkcbl	104	49	other	other	JJ
cord-277648-9kxwkcbl	104	50	identified	identify	VBN
cord-277648-9kxwkcbl	104	51	cell	cell	NN
cord-277648-9kxwkcbl	104	52	surface	surface	NN
cord-277648-9kxwkcbl	104	53	protein	protein	NN
cord-277648-9kxwkcbl	104	54	transcripts	transcript	NNS
cord-277648-9kxwkcbl	104	55	in	in	IN
cord-277648-9kxwkcbl	104	56	Figure	Figure	NNP
cord-277648-9kxwkcbl	104	57	2C	2c	NN
cord-277648-9kxwkcbl	104	58	are	be	VBP
cord-277648-9kxwkcbl	104	59	unique	unique	JJ
cord-277648-9kxwkcbl	104	60	markers	marker	NNS
cord-277648-9kxwkcbl	104	61	of	of	IN
cord-277648-9kxwkcbl	104	62	severe	severe	JJ
cord-277648-9kxwkcbl	104	63	disease	disease	NN
cord-277648-9kxwkcbl	104	64	.	.	.
cord-277648-9kxwkcbl	105	1	We	-PRON-	PRP
cord-277648-9kxwkcbl	105	2	also	also	RB
cord-277648-9kxwkcbl	105	3	sought	seek	VBD
cord-277648-9kxwkcbl	105	4	to	to	TO
cord-277648-9kxwkcbl	105	5	identify	identify	VB
cord-277648-9kxwkcbl	105	6	ARDS	ARDS	NNP
cord-277648-9kxwkcbl	105	7	-	-	HYPH
cord-277648-9kxwkcbl	105	8	specific	specific	JJ
cord-277648-9kxwkcbl	105	9	cell	cell	NN
cord-277648-9kxwkcbl	105	10	surface	surface	NN
cord-277648-9kxwkcbl	105	11	markers	marker	NNS
cord-277648-9kxwkcbl	105	12	in	in	IN
cord-277648-9kxwkcbl	105	13	the	the	DT
cord-277648-9kxwkcbl	105	14	blood	blood	NN
cord-277648-9kxwkcbl	105	15	in	in	IN
cord-277648-9kxwkcbl	105	16	order	order	NN
cord-277648-9kxwkcbl	105	17	to	to	TO
cord-277648-9kxwkcbl	105	18	nominate	nominate	VB
cord-277648-9kxwkcbl	105	19	immunophenotyping	immunophenotyping	NN
cord-277648-9kxwkcbl	105	20	markers	marker	NNS
cord-277648-9kxwkcbl	105	21	on	on	IN
cord-277648-9kxwkcbl	105	22	cells	cell	NNS
cord-277648-9kxwkcbl	105	23	that	that	WDT
cord-277648-9kxwkcbl	105	24	may	may	MD
cord-277648-9kxwkcbl	105	25	be	be	VB
cord-277648-9kxwkcbl	105	26	accessible	accessible	JJ
cord-277648-9kxwkcbl	105	27	through	through	IN
cord-277648-9kxwkcbl	105	28	a	a	DT
cord-277648-9kxwkcbl	105	29	blood	blood	NN
cord-277648-9kxwkcbl	105	30	draw	draw	NN
cord-277648-9kxwkcbl	105	31	.	.	.
cord-277648-9kxwkcbl	106	1	In	in	IN
cord-277648-9kxwkcbl	106	2	gamma	gamma	NN
cord-277648-9kxwkcbl	106	3	delta	delta	NN
cord-277648-9kxwkcbl	106	4	T	T	NNP
cord-277648-9kxwkcbl	106	5	(	(	-LRB-
cord-277648-9kxwkcbl	106	6	γδ	γδ	IN
cord-277648-9kxwkcbl	106	7	T	T	NNP
cord-277648-9kxwkcbl	106	8	)	)	-RRB-
cord-277648-9kxwkcbl	106	9	cells	cell	NNS
cord-277648-9kxwkcbl	106	10	,	,	,
cord-277648-9kxwkcbl	106	11	we	-PRON-	PRP
cord-277648-9kxwkcbl	106	12	observed	observe	VBD
cord-277648-9kxwkcbl	106	13	ARDS	ARDS	NNP
cord-277648-9kxwkcbl	106	14	-	-	HYPH
cord-277648-9kxwkcbl	106	15	specific	specific	JJ
cord-277648-9kxwkcbl	106	16	differentially	differentially	RB
cord-277648-9kxwkcbl	106	17	expressed	express	VBN
cord-277648-9kxwkcbl	106	18	genes	gene	NNS
cord-277648-9kxwkcbl	106	19	including	include	VBG
cord-277648-9kxwkcbl	106	20	the	the	DT
cord-277648-9kxwkcbl	106	21	surface	surface	NN
cord-277648-9kxwkcbl	106	22	marker	marker	NN
cord-277648-9kxwkcbl	106	23	S1PR1	S1PR1	NNP
cord-277648-9kxwkcbl	106	24	(	(	-LRB-
cord-277648-9kxwkcbl	106	25	Figure	Figure	NNP
cord-277648-9kxwkcbl	106	26	2D	2D	NNP
cord-277648-9kxwkcbl	106	27	)	)	-RRB-
cord-277648-9kxwkcbl	106	28	,	,	,
cord-277648-9kxwkcbl	106	29	a	a	DT
cord-277648-9kxwkcbl	106	30	G	g	NN
cord-277648-9kxwkcbl	106	31	-	-	HYPH
cord-277648-9kxwkcbl	106	32	protein	protein	NN
cord-277648-9kxwkcbl	106	33	coupled	couple	VBN
cord-277648-9kxwkcbl	106	34	receptor	receptor	NN
cord-277648-9kxwkcbl	106	35	that	that	WDT
cord-277648-9kxwkcbl	106	36	interacts	interact	VBZ
cord-277648-9kxwkcbl	106	37	with	with	IN
cord-277648-9kxwkcbl	106	38	multiple	multiple	JJ
cord-277648-9kxwkcbl	106	39	inflammatory	inflammatory	JJ
cord-277648-9kxwkcbl	106	40	pathways	pathway	NNS
cord-277648-9kxwkcbl	106	41	such	such	JJ
cord-277648-9kxwkcbl	106	42	as	as	IN
cord-277648-9kxwkcbl	106	43	JAK	JAK	NNP
cord-277648-9kxwkcbl	106	44	/	/	SYM
cord-277648-9kxwkcbl	106	45	STAT	STAT	NNP
cord-277648-9kxwkcbl	106	46	and	and	CC
cord-277648-9kxwkcbl	106	47	mTOR/	mTOR/	NNP
cord-277648-9kxwkcbl	107	1	PI3	PI3	NNP
cord-277648-9kxwkcbl	107	2	K	K	NNP
cord-277648-9kxwkcbl	108	1	/Akt	/Akt	NFP
cord-277648-9kxwkcbl	108	2	[	[	-LRB-
cord-277648-9kxwkcbl	108	3	41	41	CD
cord-277648-9kxwkcbl	108	4	,	,	,
cord-277648-9kxwkcbl	108	5	42	42	CD
cord-277648-9kxwkcbl	108	6	]	]	-RRB-
cord-277648-9kxwkcbl	108	7	.	.	.
cord-277648-9kxwkcbl	109	1	S1PR1	s1pr1	JJ
cord-277648-9kxwkcbl	109	2	expression	expression	NN
cord-277648-9kxwkcbl	109	3	was	be	VBD
cord-277648-9kxwkcbl	109	4	robustly	robustly	RB
cord-277648-9kxwkcbl	109	5	upregulated	upregulate	VBN
cord-277648-9kxwkcbl	109	6	in	in	IN
cord-277648-9kxwkcbl	109	7	ARDS	ARDS	NNP
cord-277648-9kxwkcbl	109	8	compared	compare	VBN
cord-277648-9kxwkcbl	109	9	to	to	IN
cord-277648-9kxwkcbl	109	10	non	non	JJ
cord-277648-9kxwkcbl	109	11	-	-	JJ
cord-277648-9kxwkcbl	109	12	ARDS	ards	JJ
cord-277648-9kxwkcbl	109	13	patients	patient	NNS
cord-277648-9kxwkcbl	109	14	(	(	-LRB-
cord-277648-9kxwkcbl	109	15	Figure	figure	NN
cord-277648-9kxwkcbl	109	16	2E	2e	NN
cord-277648-9kxwkcbl	109	17	)	)	-RRB-
cord-277648-9kxwkcbl	109	18	and	and	CC
cord-277648-9kxwkcbl	109	19	ARDS	ARDS	NNP
cord-277648-9kxwkcbl	109	20	compared	compare	VBD
cord-277648-9kxwkcbl	109	21	to	to	TO
cord-277648-9kxwkcbl	109	22	control	control	VB
cord-277648-9kxwkcbl	109	23	(	(	-LRB-
cord-277648-9kxwkcbl	109	24	Figure	figure	NN
cord-277648-9kxwkcbl	109	25	S2D	s2d	CD
cord-277648-9kxwkcbl	109	26	)	)	-RRB-
cord-277648-9kxwkcbl	109	27	,	,	,
cord-277648-9kxwkcbl	109	28	and	and	CC
cord-277648-9kxwkcbl	109	29	additionally	additionally	RB
cord-277648-9kxwkcbl	109	30	did	do	VBD
cord-277648-9kxwkcbl	109	31	not	not	RB
cord-277648-9kxwkcbl	109	32	show	show	VB
cord-277648-9kxwkcbl	109	33	upregulation	upregulation	NN
cord-277648-9kxwkcbl	109	34	between	between	IN
cord-277648-9kxwkcbl	109	35	non	non	JJ
cord-277648-9kxwkcbl	109	36	-	-	JJ
cord-277648-9kxwkcbl	109	37	ARDS	ARDS	NNP
cord-277648-9kxwkcbl	109	38	patients	patient	NNS
cord-277648-9kxwkcbl	109	39	and	and	CC
cord-277648-9kxwkcbl	109	40	controls	control	NNS
cord-277648-9kxwkcbl	109	41	.	.	.
cord-277648-9kxwkcbl	110	1	Similarly	similarly	RB
cord-277648-9kxwkcbl	110	2	to	to	IN
cord-277648-9kxwkcbl	110	3	our	-PRON-	PRP$
cord-277648-9kxwkcbl	110	4	analysis	analysis	NN
cord-277648-9kxwkcbl	110	5	of	of	IN
cord-277648-9kxwkcbl	110	6	the	the	DT
cord-277648-9kxwkcbl	110	7	BALF	BALF	NNP
cord-277648-9kxwkcbl	110	8	,	,	,
cord-277648-9kxwkcbl	110	9	we	-PRON-	PRP
cord-277648-9kxwkcbl	110	10	analyzed	analyze	VBD
cord-277648-9kxwkcbl	110	11	differential	differential	JJ
cord-277648-9kxwkcbl	110	12	expression	expression	NN
cord-277648-9kxwkcbl	110	13	of	of	IN
cord-277648-9kxwkcbl	110	14	surface	surface	NN
cord-277648-9kxwkcbl	110	15	protein	protein	NN
cord-277648-9kxwkcbl	110	16	genes	gene	NNS
cord-277648-9kxwkcbl	110	17	in	in	IN
cord-277648-9kxwkcbl	110	18	every	every	DT
cord-277648-9kxwkcbl	110	19	cell	cell	NN
cord-277648-9kxwkcbl	110	20	type	type	NN
cord-277648-9kxwkcbl	110	21	of	of	IN
cord-277648-9kxwkcbl	110	22	the	the	DT
cord-277648-9kxwkcbl	110	23	PBMC	PBMC	NNP
cord-277648-9kxwkcbl	110	24	pool	pool	NN
cord-277648-9kxwkcbl	110	25	,	,	,
cord-277648-9kxwkcbl	110	26	and	and	CC
cord-277648-9kxwkcbl	110	27	the	the	DT
cord-277648-9kxwkcbl	110	28	matrix	matrix	NN
cord-277648-9kxwkcbl	110	29	of	of	IN
cord-277648-9kxwkcbl	110	30	potential	potential	JJ
cord-277648-9kxwkcbl	110	31	markers	marker	NNS
cord-277648-9kxwkcbl	110	32	is	be	VBZ
cord-277648-9kxwkcbl	110	33	shown	show	VBN
cord-277648-9kxwkcbl	110	34	in	in	IN
cord-277648-9kxwkcbl	110	35	Figure	figure	NN
cord-277648-9kxwkcbl	110	36	2E	2e	NN
cord-277648-9kxwkcbl	110	37	.	.	.
cord-277648-9kxwkcbl	111	1	We	-PRON-	PRP
cord-277648-9kxwkcbl	111	2	found	find	VBD
cord-277648-9kxwkcbl	111	3	that	that	IN
cord-277648-9kxwkcbl	111	4	S1PR1	S1PR1	NNP
cord-277648-9kxwkcbl	111	5	was	be	VBD
cord-277648-9kxwkcbl	111	6	also	also	RB
cord-277648-9kxwkcbl	111	7	differentially	differentially	RB
cord-277648-9kxwkcbl	111	8	expressed	express	VBN
cord-277648-9kxwkcbl	111	9	in	in	IN
cord-277648-9kxwkcbl	111	10	CD8	CD8	NNP
cord-277648-9kxwkcbl	111	11	+	+	CC
cord-277648-9kxwkcbl	111	12	effector	effector	VB
cord-277648-9kxwkcbl	111	13	T	t	NN
cord-277648-9kxwkcbl	111	14	cells	cell	NNS
cord-277648-9kxwkcbl	111	15	,	,	,
cord-277648-9kxwkcbl	111	16	and	and	CC
cord-277648-9kxwkcbl	111	17	its	-PRON-	PRP$
cord-277648-9kxwkcbl	111	18	general	general	JJ
cord-277648-9kxwkcbl	111	19	expression	expression	NN
cord-277648-9kxwkcbl	111	20	on	on	IN
cord-277648-9kxwkcbl	111	21	T	t	NN
cord-277648-9kxwkcbl	111	22	cells	cell	NNS
cord-277648-9kxwkcbl	111	23	was	be	VBD
cord-277648-9kxwkcbl	111	24	verified	verify	VBN
cord-277648-9kxwkcbl	111	25	in	in	IN
cord-277648-9kxwkcbl	111	26	bulk	bulk	JJ
cord-277648-9kxwkcbl	111	27	RNA	RNA	NNP
cord-277648-9kxwkcbl	111	28	-	-	HYPH
cord-277648-9kxwkcbl	111	29	seq	seq	NN
cord-277648-9kxwkcbl	111	30	data	datum	NNS
cord-277648-9kxwkcbl	111	31	(	(	-LRB-
cord-277648-9kxwkcbl	111	32	Figure	figure	NN
cord-277648-9kxwkcbl	111	33	  	  	_SP
cord-277648-9kxwkcbl	111	34	S2F	s2f	CD
cord-277648-9kxwkcbl	111	35	)	)	-RRB-
cord-277648-9kxwkcbl	111	36	.	.	.
cord-277648-9kxwkcbl	112	1	Immunoglobulin	immunoglobulin	JJ
cord-277648-9kxwkcbl	112	2	heavy	heavy	JJ
cord-277648-9kxwkcbl	112	3	chain	chain	NN
cord-277648-9kxwkcbl	112	4	genes	gene	NNS
cord-277648-9kxwkcbl	112	5	also	also	RB
cord-277648-9kxwkcbl	112	6	appeared	appear	VBD
cord-277648-9kxwkcbl	112	7	to	to	TO
cord-277648-9kxwkcbl	112	8	be	be	VB
cord-277648-9kxwkcbl	112	9	differentially	differentially	RB
cord-277648-9kxwkcbl	112	10	expressed	express	VBN
cord-277648-9kxwkcbl	112	11	in	in	IN
cord-277648-9kxwkcbl	112	12	unexpected	unexpected	JJ
cord-277648-9kxwkcbl	112	13	blood	blood	NN
cord-277648-9kxwkcbl	112	14	cell	cell	NN
cord-277648-9kxwkcbl	112	15	types	type	NNS
cord-277648-9kxwkcbl	112	16	.	.	.
cord-277648-9kxwkcbl	113	1	In	in	IN
cord-277648-9kxwkcbl	113	2	both	both	CC
cord-277648-9kxwkcbl	113	3	BALF	BALF	NNP
cord-277648-9kxwkcbl	113	4	and	and	CC
cord-277648-9kxwkcbl	113	5	PBMCs	pbmc	NNS
cord-277648-9kxwkcbl	113	6	,	,	,
cord-277648-9kxwkcbl	113	7	we	-PRON-	PRP
cord-277648-9kxwkcbl	113	8	observed	observe	VBD
cord-277648-9kxwkcbl	113	9	that	that	IN
cord-277648-9kxwkcbl	113	10	increasing	increase	VBG
cord-277648-9kxwkcbl	113	11	disease	disease	NN
cord-277648-9kxwkcbl	113	12	severity	severity	NN
cord-277648-9kxwkcbl	113	13	was	be	VBD
cord-277648-9kxwkcbl	113	14	associated	associate	VBN
cord-277648-9kxwkcbl	113	15	with	with	IN
cord-277648-9kxwkcbl	113	16	the	the	DT
cord-277648-9kxwkcbl	113	17	common	common	JJ
cord-277648-9kxwkcbl	113	18	downregulation	downregulation	NN
cord-277648-9kxwkcbl	113	19	of	of	IN
cord-277648-9kxwkcbl	113	20	HLA	HLA	NNP
cord-277648-9kxwkcbl	113	21	class	class	NN
cord-277648-9kxwkcbl	113	22	II	II	NNP
cord-277648-9kxwkcbl	113	23	genes	gene	NNS
cord-277648-9kxwkcbl	113	24	HLADQA1	HLADQA1	NNP
cord-277648-9kxwkcbl	114	1	and	and	CC
cord-277648-9kxwkcbl	114	2	HLADQA2	HLADQA2	NNP
cord-277648-9kxwkcbl	114	3	on	on	IN
cord-277648-9kxwkcbl	114	4	CD16	CD16	NNP
cord-277648-9kxwkcbl	115	1	+	+	CC
cord-277648-9kxwkcbl	115	2	monocytes	monocyte	NNS
cord-277648-9kxwkcbl	115	3	and	and	CC
cord-277648-9kxwkcbl	115	4	BALF	BALF	NNP
cord-277648-9kxwkcbl	115	5	MPs	MPs	NNPS
cord-277648-9kxwkcbl	115	6	and	and	CC
cord-277648-9kxwkcbl	115	7	HLADRA	HLADRA	NNP
cord-277648-9kxwkcbl	115	8	on	on	IN
cord-277648-9kxwkcbl	115	9	CD14	CD14	NNP
cord-277648-9kxwkcbl	115	10	+	+	CC
cord-277648-9kxwkcbl	115	11	monocytes	monocyte	NNS
cord-277648-9kxwkcbl	115	12	and	and	CC
cord-277648-9kxwkcbl	115	13	BALF	BALF	NNP
cord-277648-9kxwkcbl	115	14	MPs	MPs	NNPS
cord-277648-9kxwkcbl	115	15	.	.	.
cord-277648-9kxwkcbl	116	1	Overall	overall	RB
cord-277648-9kxwkcbl	116	2	,	,	,
cord-277648-9kxwkcbl	116	3	these	these	DT
cord-277648-9kxwkcbl	116	4	results	result	NNS
cord-277648-9kxwkcbl	116	5	suggest	suggest	VBP
cord-277648-9kxwkcbl	116	6	cell	cell	NN
cord-277648-9kxwkcbl	116	7	surface	surface	NN
cord-277648-9kxwkcbl	116	8	proteins	protein	NNS
cord-277648-9kxwkcbl	116	9	whose	whose	WP$
cord-277648-9kxwkcbl	116	10	transcripts	transcript	NNS
cord-277648-9kxwkcbl	116	11	are	be	VBP
cord-277648-9kxwkcbl	116	12	differentially	differentially	RB
cord-277648-9kxwkcbl	116	13	expressed	express	VBN
cord-277648-9kxwkcbl	116	14	across	across	IN
cord-277648-9kxwkcbl	116	15	disease	disease	NN
cord-277648-9kxwkcbl	116	16	severity	severity	NN
cord-277648-9kxwkcbl	116	17	categories	category	NNS
cord-277648-9kxwkcbl	116	18	as	as	IN
cord-277648-9kxwkcbl	116	19	candidate	candidate	NN
cord-277648-9kxwkcbl	116	20	immunophenotyping	immunophenotyping	NN
cord-277648-9kxwkcbl	116	21	markers	marker	NNS
cord-277648-9kxwkcbl	116	22	in	in	IN
cord-277648-9kxwkcbl	116	23	cells	cell	NNS
cord-277648-9kxwkcbl	116	24	of	of	IN
cord-277648-9kxwkcbl	116	25	the	the	DT
cord-277648-9kxwkcbl	116	26	lung	lung	NN
cord-277648-9kxwkcbl	116	27	and	and	CC
cord-277648-9kxwkcbl	116	28	blood	blood	NN
cord-277648-9kxwkcbl	116	29	.	.	.
cord-277648-9kxwkcbl	117	1	To	to	TO
cord-277648-9kxwkcbl	117	2	complement	complement	VB
cord-277648-9kxwkcbl	117	3	our	-PRON-	PRP$
cord-277648-9kxwkcbl	117	4	transcriptomic	transcriptomic	JJ
cord-277648-9kxwkcbl	117	5	analysis	analysis	NN
cord-277648-9kxwkcbl	117	6	,	,	,
cord-277648-9kxwkcbl	117	7	we	-PRON-	PRP
cord-277648-9kxwkcbl	117	8	employed	employ	VBD
cord-277648-9kxwkcbl	117	9	gene	gene	NN
cord-277648-9kxwkcbl	117	10	ontology	ontology	NN
cord-277648-9kxwkcbl	117	11	(	(	-LRB-
cord-277648-9kxwkcbl	117	12	GO	GO	NNP
cord-277648-9kxwkcbl	117	13	)	)	-RRB-
cord-277648-9kxwkcbl	117	14	analysis	analysis	NN
cord-277648-9kxwkcbl	117	15	to	to	TO
cord-277648-9kxwkcbl	117	16	identify	identify	VB
cord-277648-9kxwkcbl	117	17	the	the	DT
cord-277648-9kxwkcbl	117	18	biological	biological	JJ
cord-277648-9kxwkcbl	117	19	functions	function	NNS
cord-277648-9kxwkcbl	117	20	of	of	IN
cord-277648-9kxwkcbl	117	21	DEGs	deg	NNS
cord-277648-9kxwkcbl	117	22	(	(	-LRB-
cord-277648-9kxwkcbl	117	23	Figure	figure	NN
cord-277648-9kxwkcbl	117	24	S2	s2	NN
cord-277648-9kxwkcbl	117	25	G	G	NNP
cord-277648-9kxwkcbl	117	26	-I	-I	NNP
cord-277648-9kxwkcbl	117	27	)	)	-RRB-
cord-277648-9kxwkcbl	117	28	.	.	.
cord-277648-9kxwkcbl	118	1	GO	go	VB
cord-277648-9kxwkcbl	118	2	analysis	analysis	NN
cord-277648-9kxwkcbl	118	3	of	of	IN
cord-277648-9kxwkcbl	118	4	the	the	DT
cord-277648-9kxwkcbl	118	5	DEGs	deg	NNS
cord-277648-9kxwkcbl	118	6	in	in	IN
cord-277648-9kxwkcbl	118	7	BALF	BALF	NNP
cord-277648-9kxwkcbl	118	8	and	and	CC
cord-277648-9kxwkcbl	118	9	PBMCs	PBMCs	NNP
cord-277648-9kxwkcbl	118	10	shows	show	VBZ
cord-277648-9kxwkcbl	118	11	differential	differential	JJ
cord-277648-9kxwkcbl	118	12	expression	expression	NN
cord-277648-9kxwkcbl	118	13	of	of	IN
cord-277648-9kxwkcbl	118	14	transcripts	transcript	NNS
cord-277648-9kxwkcbl	118	15	belonging	belong	VBG
cord-277648-9kxwkcbl	118	16	to	to	IN
cord-277648-9kxwkcbl	118	17	ontologies	ontology	NNS
cord-277648-9kxwkcbl	118	18	of	of	IN
cord-277648-9kxwkcbl	118	19	the	the	DT
cord-277648-9kxwkcbl	118	20	innate	innate	JJ
cord-277648-9kxwkcbl	118	21	immune	immune	JJ
cord-277648-9kxwkcbl	118	22	system	system	NN
cord-277648-9kxwkcbl	118	23	,	,	,
cord-277648-9kxwkcbl	118	24	cytokine	cytokine	NN
cord-277648-9kxwkcbl	118	25	signaling	signaling	NN
cord-277648-9kxwkcbl	118	26	,	,	,
cord-277648-9kxwkcbl	118	27	and	and	CC
cord-277648-9kxwkcbl	118	28	adaptive	adaptive	JJ
cord-277648-9kxwkcbl	118	29	immune	immune	JJ
cord-277648-9kxwkcbl	118	30	cell	cell	NN
cord-277648-9kxwkcbl	118	31	proliferation	proliferation	NN
cord-277648-9kxwkcbl	118	32	and	and	CC
cord-277648-9kxwkcbl	118	33	activation	activation	NN
cord-277648-9kxwkcbl	118	34	.	.	.
cord-277648-9kxwkcbl	119	1	To	to	TO
cord-277648-9kxwkcbl	119	2	probe	probe	VB
cord-277648-9kxwkcbl	119	3	the	the	DT
cord-277648-9kxwkcbl	119	4	molecular	molecular	JJ
cord-277648-9kxwkcbl	119	5	mechanisms	mechanism	NNS
cord-277648-9kxwkcbl	119	6	of	of	IN
cord-277648-9kxwkcbl	119	7	severe	severe	JJ
cord-277648-9kxwkcbl	119	8	COVID-19	covid-19	NN
cord-277648-9kxwkcbl	119	9	at	at	IN
cord-277648-9kxwkcbl	119	10	a	a	DT
cord-277648-9kxwkcbl	119	11	broader	broad	JJR
cord-277648-9kxwkcbl	119	12	scale	scale	NN
cord-277648-9kxwkcbl	119	13	,	,	,
cord-277648-9kxwkcbl	119	14	we	-PRON-	PRP
cord-277648-9kxwkcbl	119	15	sought	seek	VBD
cord-277648-9kxwkcbl	119	16	to	to	TO
cord-277648-9kxwkcbl	119	17	utilize	utilize	VB
cord-277648-9kxwkcbl	119	18	the	the	DT
cord-277648-9kxwkcbl	119	19	large	large	JJ
cord-277648-9kxwkcbl	119	20	number	number	NN
cord-277648-9kxwkcbl	119	21	of	of	IN
cord-277648-9kxwkcbl	119	22	differentially	differentially	RB
cord-277648-9kxwkcbl	119	23	expressed	express	VBN
cord-277648-9kxwkcbl	119	24	transcripts	transcript	NNS
cord-277648-9kxwkcbl	119	25	to	to	TO
cord-277648-9kxwkcbl	119	26	identify	identify	VB
cord-277648-9kxwkcbl	119	27	biological	biological	JJ
cord-277648-9kxwkcbl	119	28	pathways	pathway	NNS
cord-277648-9kxwkcbl	119	29	that	that	WDT
cord-277648-9kxwkcbl	119	30	are	be	VBP
cord-277648-9kxwkcbl	119	31	altered	alter	VBN
cord-277648-9kxwkcbl	119	32	across	across	IN
cord-277648-9kxwkcbl	119	33	the	the	DT
cord-277648-9kxwkcbl	119	34	spectrum	spectrum	NN
cord-277648-9kxwkcbl	119	35	of	of	IN
cord-277648-9kxwkcbl	119	36	disease	disease	NN
cord-277648-9kxwkcbl	119	37	severity	severity	NN
cord-277648-9kxwkcbl	119	38	in	in	IN
cord-277648-9kxwkcbl	119	39	the	the	DT
cord-277648-9kxwkcbl	119	40	local	local	JJ
cord-277648-9kxwkcbl	119	41	lung	lung	NN
cord-277648-9kxwkcbl	119	42	microenvironment	microenvironment	NN
cord-277648-9kxwkcbl	119	43	(	(	-LRB-
cord-277648-9kxwkcbl	119	44	BALF	BALF	NNP
cord-277648-9kxwkcbl	119	45	)	)	-RRB-
cord-277648-9kxwkcbl	119	46	and	and	CC
cord-277648-9kxwkcbl	119	47	systemic	systemic	JJ
cord-277648-9kxwkcbl	119	48	circulation	circulation	NN
cord-277648-9kxwkcbl	119	49	(	(	-LRB-
cord-277648-9kxwkcbl	119	50	PBMCs	pbmc	NNS
cord-277648-9kxwkcbl	119	51	)	)	-RRB-
cord-277648-9kxwkcbl	119	52	.	.	.
cord-277648-9kxwkcbl	120	1	Significant	significant	JJ
cord-277648-9kxwkcbl	120	2	transcriptional	transcriptional	JJ
cord-277648-9kxwkcbl	120	3	changes	change	NNS
cord-277648-9kxwkcbl	120	4	in	in	IN
cord-277648-9kxwkcbl	120	5	cells	cell	NNS
cord-277648-9kxwkcbl	120	6	of	of	IN
cord-277648-9kxwkcbl	120	7	the	the	DT
cord-277648-9kxwkcbl	120	8	BALF	BALF	NNP
cord-277648-9kxwkcbl	120	9	were	be	VBD
cord-277648-9kxwkcbl	120	10	abundant	abundant	JJ
cord-277648-9kxwkcbl	120	11	in	in	IN
cord-277648-9kxwkcbl	120	12	all	all	DT
cord-277648-9kxwkcbl	120	13	cell	cell	NN
cord-277648-9kxwkcbl	120	14	types	type	NNS
cord-277648-9kxwkcbl	120	15	with	with	IN
cord-277648-9kxwkcbl	120	16	the	the	DT
cord-277648-9kxwkcbl	120	17	exception	exception	NN
cord-277648-9kxwkcbl	120	18	of	of	IN
cord-277648-9kxwkcbl	120	19	plasma	plasma	NN
cord-277648-9kxwkcbl	120	20	cells	cell	NNS
cord-277648-9kxwkcbl	120	21	.	.	.
cord-277648-9kxwkcbl	121	1	We	-PRON-	PRP
cord-277648-9kxwkcbl	121	2	first	first	RB
cord-277648-9kxwkcbl	121	3	directed	direct	VBD
cord-277648-9kxwkcbl	121	4	our	-PRON-	PRP$
cord-277648-9kxwkcbl	121	5	attention	attention	NN
cord-277648-9kxwkcbl	121	6	to	to	IN
cord-277648-9kxwkcbl	121	7	the	the	DT
cord-277648-9kxwkcbl	121	8	epithelium	epithelium	NN
cord-277648-9kxwkcbl	121	9	,	,	,
cord-277648-9kxwkcbl	121	10	where	where	WRB
cord-277648-9kxwkcbl	121	11	substantial	substantial	JJ
cord-277648-9kxwkcbl	121	12	morphological	morphological	JJ
cord-277648-9kxwkcbl	121	13	damage	damage	NN
cord-277648-9kxwkcbl	121	14	and	and	CC
cord-277648-9kxwkcbl	121	15	histological	histological	JJ
cord-277648-9kxwkcbl	121	16	atypia	atypia	NNS
cord-277648-9kxwkcbl	121	17	were	be	VBD
cord-277648-9kxwkcbl	121	18	observed	observe	VBN
cord-277648-9kxwkcbl	121	19	in	in	IN
cord-277648-9kxwkcbl	121	20	deceased	deceased	JJ
cord-277648-9kxwkcbl	121	21	COVID-19	covid-19	CD
cord-277648-9kxwkcbl	121	22	patients	patient	NNS
cord-277648-9kxwkcbl	121	23	[	[	-LRB-
cord-277648-9kxwkcbl	121	24	1	1	CD
cord-277648-9kxwkcbl	121	25	,	,	,
cord-277648-9kxwkcbl	121	26	7	7	CD
cord-277648-9kxwkcbl	121	27	,	,	,
cord-277648-9kxwkcbl	121	28	15	15	CD
cord-277648-9kxwkcbl	121	29	,	,	,
cord-277648-9kxwkcbl	121	30	17	17	CD
cord-277648-9kxwkcbl	121	31	,	,	,
cord-277648-9kxwkcbl	121	32	16	16	CD
cord-277648-9kxwkcbl	121	33	]	]	-RRB-
cord-277648-9kxwkcbl	121	34	.	.	.
cord-277648-9kxwkcbl	122	1	At	at	IN
cord-277648-9kxwkcbl	122	2	the	the	DT
cord-277648-9kxwkcbl	122	3	level	level	NN
cord-277648-9kxwkcbl	122	4	of	of	IN
cord-277648-9kxwkcbl	122	5	individual	individual	JJ
cord-277648-9kxwkcbl	122	6	gene	gene	NN
cord-277648-9kxwkcbl	122	7	regulation	regulation	NN
cord-277648-9kxwkcbl	122	8	,	,	,
cord-277648-9kxwkcbl	122	9	we	-PRON-	PRP
cord-277648-9kxwkcbl	122	10	first	first	RB
cord-277648-9kxwkcbl	122	11	noted	note	VBD
cord-277648-9kxwkcbl	122	12	a	a	DT
cord-277648-9kxwkcbl	122	13	surprisingly	surprisingly	RB
cord-277648-9kxwkcbl	122	14	strong	strong	JJ
cord-277648-9kxwkcbl	122	15	significant	significant	JJ
cord-277648-9kxwkcbl	122	16	upregulation	upregulation	NN
cord-277648-9kxwkcbl	122	17	of	of	IN
cord-277648-9kxwkcbl	122	18	FOS	FOS	NNP
cord-277648-9kxwkcbl	122	19	and	and	CC
cord-277648-9kxwkcbl	122	20	JUN	JUN	NNP
cord-277648-9kxwkcbl	122	21	,	,	,
cord-277648-9kxwkcbl	122	22	which	which	WDT
cord-277648-9kxwkcbl	122	23	code	code	NN
cord-277648-9kxwkcbl	122	24	for	for	IN
cord-277648-9kxwkcbl	122	25	proteins	protein	NNS
cord-277648-9kxwkcbl	122	26	implicated	implicate	VBN
cord-277648-9kxwkcbl	122	27	in	in	IN
cord-277648-9kxwkcbl	122	28	the	the	DT
cord-277648-9kxwkcbl	122	29	development	development	NN
cord-277648-9kxwkcbl	122	30	of	of	IN
cord-277648-9kxwkcbl	122	31	cancer	cancer	NN
cord-277648-9kxwkcbl	122	32	(	(	-LRB-
cord-277648-9kxwkcbl	122	33	Figure	Figure	NNP
cord-277648-9kxwkcbl	122	34	3A	3a	CD
cord-277648-9kxwkcbl	122	35	)	)	-RRB-
cord-277648-9kxwkcbl	122	36	.	.	.
cord-277648-9kxwkcbl	123	1	Additionally	additionally	RB
cord-277648-9kxwkcbl	123	2	,	,	,
cord-277648-9kxwkcbl	123	3	we	-PRON-	PRP
cord-277648-9kxwkcbl	123	4	noted	note	VBD
cord-277648-9kxwkcbl	123	5	a	a	DT
cord-277648-9kxwkcbl	123	6	strong	strong	JJ
cord-277648-9kxwkcbl	123	7	significant	significant	JJ
cord-277648-9kxwkcbl	123	8	downregulation	downregulation	NN
cord-277648-9kxwkcbl	123	9	of	of	IN
cord-277648-9kxwkcbl	123	10	the	the	DT
cord-277648-9kxwkcbl	123	11	tumor	tumor	NN
cord-277648-9kxwkcbl	123	12	suppressor	suppressor	NN
cord-277648-9kxwkcbl	123	13	gene	gene	NN
cord-277648-9kxwkcbl	123	14	C2orf40	C2orf40	NNP
cord-277648-9kxwkcbl	123	15	.	.	.
cord-277648-9kxwkcbl	124	1	When	when	WRB
cord-277648-9kxwkcbl	124	2	comparing	compare	VBG
cord-277648-9kxwkcbl	124	3	ciliated	ciliated	JJ
cord-277648-9kxwkcbl	124	4	cells	cell	NNS
cord-277648-9kxwkcbl	124	5	between	between	IN
cord-277648-9kxwkcbl	124	6	moderate	moderate	JJ
cord-277648-9kxwkcbl	124	7	disease	disease	NN
cord-277648-9kxwkcbl	124	8	and	and	CC
cord-277648-9kxwkcbl	124	9	healthy	healthy	JJ
cord-277648-9kxwkcbl	124	10	control	control	NN
cord-277648-9kxwkcbl	124	11	subjects	subject	NNS
cord-277648-9kxwkcbl	124	12	(	(	-LRB-
cord-277648-9kxwkcbl	124	13	Figure	figure	NN
cord-277648-9kxwkcbl	124	14	S3A	s3a	NN
cord-277648-9kxwkcbl	124	15	)	)	-RRB-
cord-277648-9kxwkcbl	124	16	,	,	,
cord-277648-9kxwkcbl	124	17	we	-PRON-	PRP
cord-277648-9kxwkcbl	124	18	did	do	VBD
cord-277648-9kxwkcbl	124	19	not	not	RB
cord-277648-9kxwkcbl	124	20	observe	observe	VB
cord-277648-9kxwkcbl	124	21	differential	differential	JJ
cord-277648-9kxwkcbl	124	22	expression	expression	NN
cord-277648-9kxwkcbl	124	23	of	of	IN
cord-277648-9kxwkcbl	124	24	proto	proto	JJ
cord-277648-9kxwkcbl	124	25	-	-	HYPH
cord-277648-9kxwkcbl	124	26	oncogenic	oncogenic	JJ
cord-277648-9kxwkcbl	124	27	transcripts	transcript	NNS
cord-277648-9kxwkcbl	124	28	.	.	.
cord-277648-9kxwkcbl	125	1	We	-PRON-	PRP
cord-277648-9kxwkcbl	125	2	next	next	RB
cord-277648-9kxwkcbl	125	3	leveraged	leveraged	JJ
cord-277648-9kxwkcbl	125	4	gene	gene	NN
cord-277648-9kxwkcbl	125	5	set	set	VBD
cord-277648-9kxwkcbl	125	6	enrichment	enrichment	NN
cord-277648-9kxwkcbl	125	7	analysis	analysis	NN
cord-277648-9kxwkcbl	125	8	(	(	-LRB-
cord-277648-9kxwkcbl	125	9	GSEA	GSEA	NNP
cord-277648-9kxwkcbl	125	10	)	)	-RRB-
cord-277648-9kxwkcbl	125	11	to	to	TO
cord-277648-9kxwkcbl	125	12	dissect	dissect	VB
cord-277648-9kxwkcbl	125	13	pathway	pathway	NN
cord-277648-9kxwkcbl	125	14	-	-	HYPH
cord-277648-9kxwkcbl	125	15	level	level	NN
cord-277648-9kxwkcbl	125	16	regulation	regulation	NN
cord-277648-9kxwkcbl	125	17	.	.	.
cord-277648-9kxwkcbl	126	1	GSEA	GSEA	NNP
cord-277648-9kxwkcbl	126	2	provides	provide	VBZ
cord-277648-9kxwkcbl	126	3	positive	positive	JJ
cord-277648-9kxwkcbl	126	4	and	and	CC
cord-277648-9kxwkcbl	126	5	negative	negative	JJ
cord-277648-9kxwkcbl	126	6	enrichment	enrichment	NN
cord-277648-9kxwkcbl	126	7	readouts	readout	NNS
cord-277648-9kxwkcbl	126	8	;	;	:
cord-277648-9kxwkcbl	126	9	here	here	RB
cord-277648-9kxwkcbl	126	10	,	,	,
cord-277648-9kxwkcbl	126	11	we	-PRON-	PRP
cord-277648-9kxwkcbl	126	12	define	define	VBP
cord-277648-9kxwkcbl	126	13	pathways	pathway	NNS
cord-277648-9kxwkcbl	126	14	with	with	IN
cord-277648-9kxwkcbl	126	15	positive	positive	JJ
cord-277648-9kxwkcbl	126	16	normalized	normalized	JJ
cord-277648-9kxwkcbl	126	17	enrichment	enrichment	NN
cord-277648-9kxwkcbl	126	18	score	score	NN
cord-277648-9kxwkcbl	126	19	as	as	IN
cord-277648-9kxwkcbl	126	20	"	"	``
cord-277648-9kxwkcbl	126	21	enriched	enrich	VBN
cord-277648-9kxwkcbl	126	22	"	"	''
cord-277648-9kxwkcbl	126	23	and	and	CC
cord-277648-9kxwkcbl	126	24	those	those	DT
cord-277648-9kxwkcbl	126	25	with	with	IN
cord-277648-9kxwkcbl	126	26	a	a	DT
cord-277648-9kxwkcbl	126	27	negative	negative	JJ
cord-277648-9kxwkcbl	126	28	normalized	normalize	VBN
cord-277648-9kxwkcbl	126	29	enrichment	enrichment	NN
cord-277648-9kxwkcbl	126	30	score	score	NN
cord-277648-9kxwkcbl	126	31	as	as	IN
cord-277648-9kxwkcbl	126	32	"	"	``
cord-277648-9kxwkcbl	126	33	depleted	deplete	VBN
cord-277648-9kxwkcbl	126	34	"	"	''
cord-277648-9kxwkcbl	126	35	.	.	.
cord-277648-9kxwkcbl	127	1	GSEA	GSEA	NNP
cord-277648-9kxwkcbl	127	2	revealed	reveal	VBD
cord-277648-9kxwkcbl	127	3	the	the	DT
cord-277648-9kxwkcbl	127	4	enrichment	enrichment	NN
cord-277648-9kxwkcbl	127	5	of	of	IN
cord-277648-9kxwkcbl	127	6	pathways	pathway	NNS
cord-277648-9kxwkcbl	127	7	involved	involve	VBN
cord-277648-9kxwkcbl	127	8	in	in	IN
cord-277648-9kxwkcbl	127	9	the	the	DT
cord-277648-9kxwkcbl	127	10	innate	innate	JJ
cord-277648-9kxwkcbl	127	11	immune	immune	JJ
cord-277648-9kxwkcbl	127	12	response	response	NN
cord-277648-9kxwkcbl	127	13	,	,	,
cord-277648-9kxwkcbl	127	14	general	general	JJ
cord-277648-9kxwkcbl	127	15	inflammatory	inflammatory	JJ
cord-277648-9kxwkcbl	127	16	response	response	NN
cord-277648-9kxwkcbl	127	17	,	,	,
cord-277648-9kxwkcbl	127	18	and	and	CC
cord-277648-9kxwkcbl	127	19	,	,	,
cord-277648-9kxwkcbl	127	20	surprisingly	surprisingly	RB
cord-277648-9kxwkcbl	127	21	,	,	,
cord-277648-9kxwkcbl	127	22	oncogenic	oncogenic	JJ
cord-277648-9kxwkcbl	127	23	signaling	signaling	NN
cord-277648-9kxwkcbl	127	24	in	in	IN
cord-277648-9kxwkcbl	127	25	severe	severe	JJ
cord-277648-9kxwkcbl	127	26	versus	versus	IN
cord-277648-9kxwkcbl	127	27	moderate	moderate	JJ
cord-277648-9kxwkcbl	127	28	donors	donor	NNS
cord-277648-9kxwkcbl	127	29	.	.	.
cord-277648-9kxwkcbl	128	1	Specifically	specifically	RB
cord-277648-9kxwkcbl	128	2	,	,	,
cord-277648-9kxwkcbl	128	3	we	-PRON-	PRP
cord-277648-9kxwkcbl	128	4	observed	observe	VBD
cord-277648-9kxwkcbl	128	5	the	the	DT
cord-277648-9kxwkcbl	128	6	significant	significant	JJ
cord-277648-9kxwkcbl	128	7	enrichment	enrichment	NN
cord-277648-9kxwkcbl	128	8	of	of	IN
cord-277648-9kxwkcbl	128	9	the	the	DT
cord-277648-9kxwkcbl	128	10	epithelial	epithelial	NN
cord-277648-9kxwkcbl	128	11	-	-	HYPH
cord-277648-9kxwkcbl	128	12	tomesenchymal	tomesenchymal	JJ
cord-277648-9kxwkcbl	128	13	transition	transition	NN
cord-277648-9kxwkcbl	128	14	,	,	,
cord-277648-9kxwkcbl	128	15	K	K	NNP
cord-277648-9kxwkcbl	128	16	-	-	HYPH
cord-277648-9kxwkcbl	128	17	Ras	Ras	NNP
cord-277648-9kxwkcbl	128	18	,	,	,
cord-277648-9kxwkcbl	128	19	PI3K	PI3K	NNP
cord-277648-9kxwkcbl	128	20	/	/	SYM
cord-277648-9kxwkcbl	128	21	Akt	Akt	NNP
cord-277648-9kxwkcbl	128	22	and	and	CC
cord-277648-9kxwkcbl	128	23	p53	p53	NN
cord-277648-9kxwkcbl	128	24	pathways	pathway	NNS
cord-277648-9kxwkcbl	128	25	in	in	IN
cord-277648-9kxwkcbl	128	26	addition	addition	NN
cord-277648-9kxwkcbl	128	27	to	to	IN
cord-277648-9kxwkcbl	128	28	the	the	DT
cord-277648-9kxwkcbl	128	29	TNF	TNF	NNP
cord-277648-9kxwkcbl	128	30	-	-	HYPH
cord-277648-9kxwkcbl	128	31	α	α	NNP
cord-277648-9kxwkcbl	128	32	signaling	signal	VBG
cord-277648-9kxwkcbl	128	33	via	via	IN
cord-277648-9kxwkcbl	128	34	NF	nf	NN
cord-277648-9kxwkcbl	128	35	-	-	HYPH
cord-277648-9kxwkcbl	128	36	κB	κB	NNP
cord-277648-9kxwkcbl	128	37	and	and	CC
cord-277648-9kxwkcbl	128	38	IL-2	IL-2	NNP
cord-277648-9kxwkcbl	128	39	/	/	SYM
cord-277648-9kxwkcbl	128	40	STAT5	STAT5	NNP
cord-277648-9kxwkcbl	128	41	pathways	pathway	NNS
cord-277648-9kxwkcbl	128	42	.	.	.
cord-277648-9kxwkcbl	129	1	When	when	WRB
cord-277648-9kxwkcbl	129	2	we	-PRON-	PRP
cord-277648-9kxwkcbl	129	3	increased	increase	VBD
cord-277648-9kxwkcbl	129	4	this	this	DT
cord-277648-9kxwkcbl	129	5	analysis	analysis	NN
cord-277648-9kxwkcbl	129	6	to	to	TO
cord-277648-9kxwkcbl	129	7	include	include	VB
cord-277648-9kxwkcbl	129	8	all	all	DT
cord-277648-9kxwkcbl	129	9	of	of	IN
cord-277648-9kxwkcbl	129	10	the	the	DT
cord-277648-9kxwkcbl	129	11	cell	cell	NN
cord-277648-9kxwkcbl	129	12	types	type	NNS
cord-277648-9kxwkcbl	129	13	found	find	VBN
cord-277648-9kxwkcbl	129	14	in	in	IN
cord-277648-9kxwkcbl	129	15	the	the	DT
cord-277648-9kxwkcbl	129	16	BALF	BALF	NNP
cord-277648-9kxwkcbl	130	1	(	(	-LRB-
cord-277648-9kxwkcbl	130	2	Figure	figure	NN
cord-277648-9kxwkcbl	130	3	3A	3a	CD
cord-277648-9kxwkcbl	131	1	We	-PRON-	PRP
cord-277648-9kxwkcbl	131	2	next	next	RB
cord-277648-9kxwkcbl	131	3	investigated	investigate	VBN
cord-277648-9kxwkcbl	131	4	pathway	pathway	NN
cord-277648-9kxwkcbl	131	5	-	-	HYPH
cord-277648-9kxwkcbl	131	6	level	level	NN
cord-277648-9kxwkcbl	131	7	changes	change	NNS
cord-277648-9kxwkcbl	131	8	occurring	occur	VBG
cord-277648-9kxwkcbl	131	9	in	in	IN
cord-277648-9kxwkcbl	131	10	PBMCs	pbmc	NNS
cord-277648-9kxwkcbl	131	11	and	and	CC
cord-277648-9kxwkcbl	131	12	found	find	VBD
cord-277648-9kxwkcbl	131	13	that	that	IN
cord-277648-9kxwkcbl	131	14	differential	differential	JJ
cord-277648-9kxwkcbl	131	15	gene	gene	NN
cord-277648-9kxwkcbl	131	16	expression	expression	NN
cord-277648-9kxwkcbl	131	17	between	between	IN
cord-277648-9kxwkcbl	131	18	ARDS	ARDS	NNP
cord-277648-9kxwkcbl	131	19	and	and	CC
cord-277648-9kxwkcbl	131	20	non	non	NNP
cord-277648-9kxwkcbl	131	21	-	-	JJ
cord-277648-9kxwkcbl	131	22	ARDS	ARDS	NNP
cord-277648-9kxwkcbl	131	23	patients	patient	NNS
cord-277648-9kxwkcbl	131	24	supported	support	VBD
cord-277648-9kxwkcbl	131	25	the	the	DT
cord-277648-9kxwkcbl	131	26	detection	detection	NN
cord-277648-9kxwkcbl	131	27	of	of	IN
cord-277648-9kxwkcbl	131	28	statistically	statistically	RB
cord-277648-9kxwkcbl	131	29	enriched	enrich	VBN
cord-277648-9kxwkcbl	131	30	pathways	pathway	NNS
cord-277648-9kxwkcbl	131	31	through	through	IN
cord-277648-9kxwkcbl	131	32	GSEA	GSEA	NNP
cord-277648-9kxwkcbl	131	33	.	.	.
cord-277648-9kxwkcbl	132	1	We	-PRON-	PRP
cord-277648-9kxwkcbl	132	2	first	first	RB
cord-277648-9kxwkcbl	132	3	examined	examine	VBD
cord-277648-9kxwkcbl	132	4	CD14	CD14	NNP
cord-277648-9kxwkcbl	132	5	+	+	CC
cord-277648-9kxwkcbl	132	6	blood	blood	NN
cord-277648-9kxwkcbl	132	7	monocytes	monocyte	NNS
cord-277648-9kxwkcbl	132	8	,	,	,
cord-277648-9kxwkcbl	132	9	a	a	DT
cord-277648-9kxwkcbl	132	10	cell	cell	NN
cord-277648-9kxwkcbl	132	11	type	type	NN
cord-277648-9kxwkcbl	132	12	whose	whose	WP$
cord-277648-9kxwkcbl	132	13	severe	severe	JJ
cord-277648-9kxwkcbl	132	14	disease	disease	NN
cord-277648-9kxwkcbl	132	15	response	response	NN
cord-277648-9kxwkcbl	132	16	could	could	MD
cord-277648-9kxwkcbl	132	17	be	be	VB
cord-277648-9kxwkcbl	132	18	compared	compare	VBN
cord-277648-9kxwkcbl	132	19	to	to	IN
cord-277648-9kxwkcbl	132	20	that	that	DT
cord-277648-9kxwkcbl	132	21	of	of	IN
cord-277648-9kxwkcbl	132	22	BALF	BALF	NNP
cord-277648-9kxwkcbl	132	23	MPs	MPs	NNPS
cord-277648-9kxwkcbl	132	24	.	.	.
cord-277648-9kxwkcbl	133	1	In	in	IN
cord-277648-9kxwkcbl	133	2	ARDS	ARDS	NNP
cord-277648-9kxwkcbl	133	3	patients	patient	NNS
cord-277648-9kxwkcbl	133	4	,	,	,
cord-277648-9kxwkcbl	133	5	CD14	CD14	NNP
cord-277648-9kxwkcbl	133	6	+	+	CC
cord-277648-9kxwkcbl	133	7	monocytes	monocyte	NNS
cord-277648-9kxwkcbl	133	8	demonstrated	demonstrate	VBD
cord-277648-9kxwkcbl	133	9	pronounced	pronounced	JJ
cord-277648-9kxwkcbl	133	10	downregulation	downregulation	NN
cord-277648-9kxwkcbl	133	11	of	of	IN
cord-277648-9kxwkcbl	133	12	ISG15	ISG15	NNP
cord-277648-9kxwkcbl	133	13	,	,	,
cord-277648-9kxwkcbl	133	14	TNFAIP3	TNFAIP3	NNS
cord-277648-9kxwkcbl	133	15	,	,	,
cord-277648-9kxwkcbl	133	16	and	and	CC
cord-277648-9kxwkcbl	133	17	NFKBIA	NFKBIA	NNP
cord-277648-9kxwkcbl	133	18	compared	compare	VBN
cord-277648-9kxwkcbl	133	19	to	to	IN
cord-277648-9kxwkcbl	133	20	non	non	JJ
cord-277648-9kxwkcbl	133	21	-	-	JJ
cord-277648-9kxwkcbl	133	22	ARDS	ARDS	NNP
cord-277648-9kxwkcbl	133	23	patients	patient	NNS
cord-277648-9kxwkcbl	133	24	,	,	,
cord-277648-9kxwkcbl	133	25	manifesting	manifest	VBG
cord-277648-9kxwkcbl	133	26	in	in	IN
cord-277648-9kxwkcbl	133	27	the	the	DT
cord-277648-9kxwkcbl	133	28	depletion	depletion	NN
cord-277648-9kxwkcbl	133	29	of	of	IN
cord-277648-9kxwkcbl	133	30	the	the	DT
cord-277648-9kxwkcbl	133	31	IFN	IFN	NNP
cord-277648-9kxwkcbl	133	32	-	-	HYPH
cord-277648-9kxwkcbl	133	33	α	α	NNP
cord-277648-9kxwkcbl	133	34	,	,	,
cord-277648-9kxwkcbl	133	35	IFN	IFN	NNP
cord-277648-9kxwkcbl	133	36	-	-	HYPH
cord-277648-9kxwkcbl	133	37	γ	γ	NNP
cord-277648-9kxwkcbl	133	38	,	,	,
cord-277648-9kxwkcbl	133	39	and	and	CC
cord-277648-9kxwkcbl	133	40	TNF	TNF	NNP
cord-277648-9kxwkcbl	133	41	-	-	HYPH
cord-277648-9kxwkcbl	133	42	α	α	NNP
cord-277648-9kxwkcbl	133	43	signaling	signal	VBG
cord-277648-9kxwkcbl	133	44	via	via	IN
cord-277648-9kxwkcbl	133	45	NF	nf	NN
cord-277648-9kxwkcbl	133	46	-	-	HYPH
cord-277648-9kxwkcbl	133	47	κB	κB	NNP
cord-277648-9kxwkcbl	133	48	pathways	pathway	NNS
cord-277648-9kxwkcbl	133	49	(	(	-LRB-
cord-277648-9kxwkcbl	133	50	Figure	figure	NN
cord-277648-9kxwkcbl	133	51	3B	3b	CD
cord-277648-9kxwkcbl	133	52	)	)	-RRB-
cord-277648-9kxwkcbl	133	53	.	.	.
cord-277648-9kxwkcbl	134	1	Expression	expression	NN
cord-277648-9kxwkcbl	134	2	of	of	IN
cord-277648-9kxwkcbl	134	3	the	the	DT
cord-277648-9kxwkcbl	134	4	immunoglobulin	immunoglobulin	NN
cord-277648-9kxwkcbl	134	5	G	G	NNP
cord-277648-9kxwkcbl	134	6	and	and	CC
cord-277648-9kxwkcbl	134	7	M	M	NNP
cord-277648-9kxwkcbl	134	8	heavy	heavy	JJ
cord-277648-9kxwkcbl	134	9	chains	chain	NNS
cord-277648-9kxwkcbl	134	10	appeared	appear	VBD
cord-277648-9kxwkcbl	134	11	to	to	TO
cord-277648-9kxwkcbl	134	12	be	be	VB
cord-277648-9kxwkcbl	134	13	altered	alter	VBN
cord-277648-9kxwkcbl	134	14	at	at	IN
cord-277648-9kxwkcbl	134	15	the	the	DT
cord-277648-9kxwkcbl	134	16	transcriptional	transcriptional	JJ
cord-277648-9kxwkcbl	134	17	level	level	NN
cord-277648-9kxwkcbl	134	18	but	but	CC
cord-277648-9kxwkcbl	134	19	did	do	VBD
cord-277648-9kxwkcbl	134	20	not	not	RB
cord-277648-9kxwkcbl	134	21	contribute	contribute	VB
cord-277648-9kxwkcbl	134	22	to	to	IN
cord-277648-9kxwkcbl	134	23	significantly	significantly	RB
cord-277648-9kxwkcbl	134	24	enriched	enrich	VBN
cord-277648-9kxwkcbl	134	25	pathways	pathway	NNS
cord-277648-9kxwkcbl	134	26	.	.	.
cord-277648-9kxwkcbl	135	1	When	when	WRB
cord-277648-9kxwkcbl	135	2	expanding	expand	VBG
cord-277648-9kxwkcbl	135	3	this	this	DT
cord-277648-9kxwkcbl	135	4	analysis	analysis	NN
cord-277648-9kxwkcbl	135	5	to	to	IN
cord-277648-9kxwkcbl	135	6	all	all	DT
cord-277648-9kxwkcbl	135	7	PBMC	PBMC	NNP
cord-277648-9kxwkcbl	135	8	cell	cell	NN
cord-277648-9kxwkcbl	135	9	types	type	NNS
cord-277648-9kxwkcbl	135	10	(	(	-LRB-
cord-277648-9kxwkcbl	135	11	Figure	figure	NN
cord-277648-9kxwkcbl	135	12	3B	3b	CD
cord-277648-9kxwkcbl	135	13	)	)	-RRB-
cord-277648-9kxwkcbl	135	14	,	,	,
cord-277648-9kxwkcbl	135	15	we	-PRON-	PRP
cord-277648-9kxwkcbl	135	16	observed	observe	VBD
cord-277648-9kxwkcbl	135	17	a	a	DT
cord-277648-9kxwkcbl	135	18	striking	striking	JJ
cord-277648-9kxwkcbl	135	19	depletion	depletion	NN
cord-277648-9kxwkcbl	135	20	of	of	IN
cord-277648-9kxwkcbl	135	21	IFN	IFN	NNP
cord-277648-9kxwkcbl	135	22	-	-	HYPH
cord-277648-9kxwkcbl	135	23	α	α	NNP
cord-277648-9kxwkcbl	135	24	,	,	,
cord-277648-9kxwkcbl	135	25	IFN	IFN	NNP
cord-277648-9kxwkcbl	135	26	-	-	HYPH
cord-277648-9kxwkcbl	135	27	γ	γ	NNP
cord-277648-9kxwkcbl	135	28	,	,	,
cord-277648-9kxwkcbl	135	29	and	and	CC
cord-277648-9kxwkcbl	135	30	TNF	TNF	NNP
cord-277648-9kxwkcbl	135	31	-	-	HYPH
cord-277648-9kxwkcbl	135	32	α	α	NNP
cord-277648-9kxwkcbl	135	33	signaling	signal	VBG
cord-277648-9kxwkcbl	135	34	via	via	IN
cord-277648-9kxwkcbl	135	35	NF	nf	NN
cord-277648-9kxwkcbl	135	36	-	-	HYPH
cord-277648-9kxwkcbl	135	37	κB	κB	NNP
cord-277648-9kxwkcbl	135	38	pathways	pathway	NNS
cord-277648-9kxwkcbl	135	39	in	in	IN
cord-277648-9kxwkcbl	135	40	a	a	DT
cord-277648-9kxwkcbl	135	41	conserved	conserve	VBN
cord-277648-9kxwkcbl	135	42	trend	trend	NN
cord-277648-9kxwkcbl	135	43	across	across	IN
cord-277648-9kxwkcbl	135	44	nearly	nearly	RB
cord-277648-9kxwkcbl	135	45	every	every	DT
cord-277648-9kxwkcbl	135	46	cell	cell	NN
cord-277648-9kxwkcbl	135	47	type	type	NN
cord-277648-9kxwkcbl	135	48	.	.	.
cord-277648-9kxwkcbl	136	1	The	the	DT
cord-277648-9kxwkcbl	136	2	IL-2	IL-2	NNP
cord-277648-9kxwkcbl	136	3	/	/	SYM
cord-277648-9kxwkcbl	136	4	STAT5	STAT5	NNP
cord-277648-9kxwkcbl	136	5	and	and	CC
cord-277648-9kxwkcbl	136	6	IL-6	IL-6	NNP
cord-277648-9kxwkcbl	136	7	/	/	SYM
cord-277648-9kxwkcbl	136	8	JAK	JAK	NNP
cord-277648-9kxwkcbl	136	9	/	/	SYM
cord-277648-9kxwkcbl	136	10	STAT3	STAT3	NNP
cord-277648-9kxwkcbl	136	11	pathways	pathway	NNS
cord-277648-9kxwkcbl	136	12	did	do	VBD
cord-277648-9kxwkcbl	136	13	not	not	RB
cord-277648-9kxwkcbl	136	14	appear	appear	VB
cord-277648-9kxwkcbl	136	15	to	to	TO
cord-277648-9kxwkcbl	136	16	be	be	VB
cord-277648-9kxwkcbl	136	17	significantly	significantly	RB
cord-277648-9kxwkcbl	136	18	altered	alter	VBN
cord-277648-9kxwkcbl	136	19	in	in	IN
cord-277648-9kxwkcbl	136	20	the	the	DT
cord-277648-9kxwkcbl	136	21	majority	majority	NN
cord-277648-9kxwkcbl	136	22	of	of	IN
cord-277648-9kxwkcbl	136	23	cell	cell	NN
cord-277648-9kxwkcbl	136	24	types	type	NNS
cord-277648-9kxwkcbl	136	25	.	.	.
cord-277648-9kxwkcbl	137	1	Comparing	compare	VBG
cord-277648-9kxwkcbl	137	2	PBMCs	pbmc	NNS
cord-277648-9kxwkcbl	137	3	of	of	IN
cord-277648-9kxwkcbl	137	4	non	non	JJ
cord-277648-9kxwkcbl	137	5	-	-	JJ
cord-277648-9kxwkcbl	137	6	ARDS	ARDS	NNP
cord-277648-9kxwkcbl	137	7	donors	donor	NNS
cord-277648-9kxwkcbl	137	8	to	to	IN
cord-277648-9kxwkcbl	137	9	healthy	healthy	JJ
cord-277648-9kxwkcbl	137	10	controls	control	NNS
cord-277648-9kxwkcbl	137	11	revealed	reveal	VBD
cord-277648-9kxwkcbl	137	12	a	a	DT
cord-277648-9kxwkcbl	137	13	strong	strong	JJ
cord-277648-9kxwkcbl	137	14	enrichment	enrichment	NN
cord-277648-9kxwkcbl	137	15	of	of	IN
cord-277648-9kxwkcbl	137	16	the	the	DT
cord-277648-9kxwkcbl	137	17	IFN	IFN	NNP
cord-277648-9kxwkcbl	137	18	-	-	HYPH
cord-277648-9kxwkcbl	137	19	α	α	NNP
cord-277648-9kxwkcbl	137	20	,	,	,
cord-277648-9kxwkcbl	137	21	IFN	IFN	NNP
cord-277648-9kxwkcbl	137	22	-	-	HYPH
cord-277648-9kxwkcbl	137	23	γ	γ	NNP
cord-277648-9kxwkcbl	137	24	,	,	,
cord-277648-9kxwkcbl	137	25	and	and	CC
cord-277648-9kxwkcbl	137	26	TNF	TNF	NNP
cord-277648-9kxwkcbl	137	27	-	-	HYPH
cord-277648-9kxwkcbl	137	28	α	α	NNP
cord-277648-9kxwkcbl	137	29	signaling	signal	VBG
cord-277648-9kxwkcbl	137	30	via	via	IN
cord-277648-9kxwkcbl	137	31	NF	nf	NN
cord-277648-9kxwkcbl	137	32	-	-	HYPH
cord-277648-9kxwkcbl	137	33	κB	κB	NNP
cord-277648-9kxwkcbl	137	34	pathways	pathway	NNS
cord-277648-9kxwkcbl	137	35	,	,	,
cord-277648-9kxwkcbl	137	36	as	as	RB
cord-277648-9kxwkcbl	137	37	well	well	RB
cord-277648-9kxwkcbl	137	38	as	as	IN
cord-277648-9kxwkcbl	137	39	some	some	DT
cord-277648-9kxwkcbl	137	40	inclusion	inclusion	NN
cord-277648-9kxwkcbl	137	41	of	of	IN
cord-277648-9kxwkcbl	137	42	the	the	DT
cord-277648-9kxwkcbl	137	43	IL-2	IL-2	NNP
cord-277648-9kxwkcbl	137	44	/	/	SYM
cord-277648-9kxwkcbl	137	45	STAT5	STAT5	NNP
cord-277648-9kxwkcbl	137	46	and	and	CC
cord-277648-9kxwkcbl	137	47	IL-6	IL-6	NNP
cord-277648-9kxwkcbl	137	48	/	/	SYM
cord-277648-9kxwkcbl	137	49	JAK	JAK	NNP
cord-277648-9kxwkcbl	137	50	/	/	SYM
cord-277648-9kxwkcbl	137	51	STAT3	STAT3	NNP
cord-277648-9kxwkcbl	137	52	pathways	pathway	NNS
cord-277648-9kxwkcbl	137	53	(	(	-LRB-
cord-277648-9kxwkcbl	137	54	Figure	figure	NN
cord-277648-9kxwkcbl	137	55	  	  	_SP
cord-277648-9kxwkcbl	137	56	S3B	s3b	NN
cord-277648-9kxwkcbl	137	57	)	)	-RRB-
cord-277648-9kxwkcbl	137	58	.	.	.
cord-277648-9kxwkcbl	138	1	Interestingly	interestingly	RB
cord-277648-9kxwkcbl	138	2	,	,	,
cord-277648-9kxwkcbl	138	3	comparing	compare	VBG
cord-277648-9kxwkcbl	138	4	ARDS	ARDS	NNP
cord-277648-9kxwkcbl	138	5	donors	donor	NNS
cord-277648-9kxwkcbl	138	6	to	to	IN
cord-277648-9kxwkcbl	138	7	healthy	healthy	JJ
cord-277648-9kxwkcbl	138	8	controls	control	NNS
cord-277648-9kxwkcbl	138	9	showed	show	VBD
cord-277648-9kxwkcbl	138	10	that	that	IN
cord-277648-9kxwkcbl	138	11	these	these	DT
cord-277648-9kxwkcbl	138	12	same	same	JJ
cord-277648-9kxwkcbl	138	13	pathways	pathway	NNS
cord-277648-9kxwkcbl	138	14	exhibited	exhibit	VBD
cord-277648-9kxwkcbl	138	15	weaker	weak	JJR
cord-277648-9kxwkcbl	138	16	enrichment	enrichment	NN
cord-277648-9kxwkcbl	138	17	(	(	-LRB-
cord-277648-9kxwkcbl	138	18	Figure	figure	NN
cord-277648-9kxwkcbl	138	19	S3E	s3e	CD
cord-277648-9kxwkcbl	138	20	)	)	-RRB-
cord-277648-9kxwkcbl	138	21	.	.	.
cord-277648-9kxwkcbl	139	1	To	to	TO
cord-277648-9kxwkcbl	139	2	establish	establish	VB
cord-277648-9kxwkcbl	139	3	a	a	DT
cord-277648-9kxwkcbl	139	4	comparison	comparison	NN
cord-277648-9kxwkcbl	139	5	between	between	IN
cord-277648-9kxwkcbl	139	6	blood	blood	NN
cord-277648-9kxwkcbl	139	7	monocytes	monocyte	NNS
cord-277648-9kxwkcbl	139	8	and	and	CC
cord-277648-9kxwkcbl	139	9	BALF	BALF	NNP
cord-277648-9kxwkcbl	139	10	MPs	MPs	NNPS
cord-277648-9kxwkcbl	139	11	and	and	CC
cord-277648-9kxwkcbl	139	12	explore	explore	VB
cord-277648-9kxwkcbl	139	13	the	the	DT
cord-277648-9kxwkcbl	139	14	heterogeneity	heterogeneity	NN
cord-277648-9kxwkcbl	139	15	of	of	IN
cord-277648-9kxwkcbl	139	16	BALF	BALF	NNP
cord-277648-9kxwkcbl	139	17	MPs	MPs	NNPS
cord-277648-9kxwkcbl	139	18	observed	observe	VBD
cord-277648-9kxwkcbl	139	19	in	in	IN
cord-277648-9kxwkcbl	139	20	our	-PRON-	PRP$
cord-277648-9kxwkcbl	139	21	dataset	dataset	NN
cord-277648-9kxwkcbl	139	22	,	,	,
cord-277648-9kxwkcbl	139	23	we	-PRON-	PRP
cord-277648-9kxwkcbl	139	24	analyzed	analyze	VBD
cord-277648-9kxwkcbl	139	25	differential	differential	JJ
cord-277648-9kxwkcbl	139	26	expression	expression	NN
cord-277648-9kxwkcbl	139	27	and	and	CC
cord-277648-9kxwkcbl	139	28	pathway	pathway	NN
cord-277648-9kxwkcbl	139	29	-	-	HYPH
cord-277648-9kxwkcbl	139	30	level	level	NN
cord-277648-9kxwkcbl	139	31	responses	response	NNS
cord-277648-9kxwkcbl	139	32	across	across	IN
cord-277648-9kxwkcbl	139	33	14	14	CD
cord-277648-9kxwkcbl	139	34	of	of	IN
cord-277648-9kxwkcbl	139	35	the	the	DT
cord-277648-9kxwkcbl	139	36	16	16	CD
cord-277648-9kxwkcbl	139	37	clusters	cluster	NNS
cord-277648-9kxwkcbl	139	38	resulting	result	VBG
cord-277648-9kxwkcbl	139	39	from	from	IN
cord-277648-9kxwkcbl	139	40	iterative	iterative	JJ
cord-277648-9kxwkcbl	139	41	data	data	NN
cord-277648-9kxwkcbl	139	42	integration	integration	NN
cord-277648-9kxwkcbl	139	43	of	of	IN
cord-277648-9kxwkcbl	139	44	the	the	DT
cord-277648-9kxwkcbl	139	45	MP	MP	NNP
cord-277648-9kxwkcbl	139	46	population	population	NN
cord-277648-9kxwkcbl	139	47	.	.	.
cord-277648-9kxwkcbl	140	1	Two	two	CD
cord-277648-9kxwkcbl	140	2	clusters	cluster	NNS
cord-277648-9kxwkcbl	140	3	containing	contain	VBG
cord-277648-9kxwkcbl	140	4	probable	probable	JJ
cord-277648-9kxwkcbl	140	5	doublets	doublet	NNS
cord-277648-9kxwkcbl	140	6	were	be	VBD
cord-277648-9kxwkcbl	140	7	excluded	exclude	VBN
cord-277648-9kxwkcbl	140	8	from	from	IN
cord-277648-9kxwkcbl	140	9	the	the	DT
cord-277648-9kxwkcbl	140	10	analysis	analysis	NN
cord-277648-9kxwkcbl	140	11	,	,	,
cord-277648-9kxwkcbl	140	12	namely	namely	RB
cord-277648-9kxwkcbl	140	13	cluster	cluster	NN
cord-277648-9kxwkcbl	140	14	12	12	CD
cord-277648-9kxwkcbl	140	15	(	(	-LRB-
cord-277648-9kxwkcbl	140	16	CD68+/CD3D+	CD68+/CD3D+	NNS
cord-277648-9kxwkcbl	140	17	)	)	-RRB-
cord-277648-9kxwkcbl	140	18	and	and	CC
cord-277648-9kxwkcbl	140	19	To	to	TO
cord-277648-9kxwkcbl	140	20	nominate	nominate	VB
cord-277648-9kxwkcbl	140	21	potential	potential	JJ
cord-277648-9kxwkcbl	140	22	transcription	transcription	NN
cord-277648-9kxwkcbl	140	23	factors	factor	NNS
cord-277648-9kxwkcbl	140	24	related	relate	VBN
cord-277648-9kxwkcbl	140	25	to	to	IN
cord-277648-9kxwkcbl	140	26	differentially	differentially	RB
cord-277648-9kxwkcbl	140	27	expressed	express	VBN
cord-277648-9kxwkcbl	140	28	gene	gene	NN
cord-277648-9kxwkcbl	140	29	sets	set	NNS
cord-277648-9kxwkcbl	140	30	,	,	,
cord-277648-9kxwkcbl	140	31	we	-PRON-	PRP
cord-277648-9kxwkcbl	140	32	sought	seek	VBD
cord-277648-9kxwkcbl	140	33	to	to	TO
cord-277648-9kxwkcbl	140	34	identify	identify	VB
cord-277648-9kxwkcbl	140	35	transcription	transcription	NN
cord-277648-9kxwkcbl	140	36	factors	factor	NNS
cord-277648-9kxwkcbl	140	37	linked	link	VBN
cord-277648-9kxwkcbl	140	38	to	to	IN
cord-277648-9kxwkcbl	140	39	DEG	deg	NN
cord-277648-9kxwkcbl	140	40	lists	list	NNS
cord-277648-9kxwkcbl	140	41	using	use	VBG
cord-277648-9kxwkcbl	140	42	the	the	DT
cord-277648-9kxwkcbl	140	43	ENCODE	ENCODE	NNP
cord-277648-9kxwkcbl	140	44	and	and	CC
cord-277648-9kxwkcbl	140	45	ChEA	ChEA	NNP
cord-277648-9kxwkcbl	140	46	ChIP	ChIP	NNP
cord-277648-9kxwkcbl	140	47	-	-	HYPH
cord-277648-9kxwkcbl	140	48	X	x	NN
cord-277648-9kxwkcbl	140	49	databases	database	NNS
cord-277648-9kxwkcbl	140	50	.	.	.
cord-277648-9kxwkcbl	141	1	Consistent	consistent	JJ
cord-277648-9kxwkcbl	141	2	with	with	IN
cord-277648-9kxwkcbl	141	3	the	the	DT
cord-277648-9kxwkcbl	141	4	identified	identify	VBN
cord-277648-9kxwkcbl	141	5	activity	activity	NN
cord-277648-9kxwkcbl	141	6	of	of	IN
cord-277648-9kxwkcbl	141	7	the	the	DT
cord-277648-9kxwkcbl	141	8	IL-6	IL-6	NNP
cord-277648-9kxwkcbl	141	9	/	/	SYM
cord-277648-9kxwkcbl	141	10	JAK	JAK	NNP
cord-277648-9kxwkcbl	141	11	/	/	SYM
cord-277648-9kxwkcbl	141	12	STAT3	STAT3	NNP
cord-277648-9kxwkcbl	141	13	pathway	pathway	NN
cord-277648-9kxwkcbl	141	14	,	,	,
cord-277648-9kxwkcbl	141	15	we	-PRON-	PRP
cord-277648-9kxwkcbl	141	16	observed	observe	VBD
cord-277648-9kxwkcbl	141	17	enrichment	enrichment	NN
cord-277648-9kxwkcbl	141	18	of	of	IN
cord-277648-9kxwkcbl	141	19	STAT3	STAT3	NNP
cord-277648-9kxwkcbl	141	20	in	in	IN
cord-277648-9kxwkcbl	141	21	many	many	JJ
cord-277648-9kxwkcbl	141	22	cells	cell	NNS
cord-277648-9kxwkcbl	141	23	of	of	IN
cord-277648-9kxwkcbl	141	24	the	the	DT
cord-277648-9kxwkcbl	141	25	BALF	BALF	NNP
cord-277648-9kxwkcbl	141	26	(	(	-LRB-
cord-277648-9kxwkcbl	141	27	Figure	figure	NN
cord-277648-9kxwkcbl	141	28	S3	S3	NNP
cord-277648-9kxwkcbl	141	29	G	G	NNP
cord-277648-9kxwkcbl	141	30	)	)	-RRB-
cord-277648-9kxwkcbl	141	31	.	.	.
cord-277648-9kxwkcbl	142	1	CEBPB	CEBPB	NNP
cord-277648-9kxwkcbl	142	2	and	and	CC
cord-277648-9kxwkcbl	142	3	CEBPD	CEBPD	NNP
cord-277648-9kxwkcbl	142	4	appeared	appear	VBD
cord-277648-9kxwkcbl	142	5	to	to	TO
cord-277648-9kxwkcbl	142	6	be	be	VB
cord-277648-9kxwkcbl	142	7	depleted	deplete	VBN
cord-277648-9kxwkcbl	142	8	in	in	IN
cord-277648-9kxwkcbl	142	9	the	the	DT
cord-277648-9kxwkcbl	142	10	PBMC	PBMC	NNP
cord-277648-9kxwkcbl	142	11	but	but	CC
cord-277648-9kxwkcbl	142	12	enriched	enrich	VBN
cord-277648-9kxwkcbl	142	13	in	in	IN
cord-277648-9kxwkcbl	142	14	the	the	DT
cord-277648-9kxwkcbl	142	15	BALF	BALF	NNP
cord-277648-9kxwkcbl	142	16	,	,	,
cord-277648-9kxwkcbl	142	17	and	and	CC
cord-277648-9kxwkcbl	143	1	opposite	opposite	JJ
cord-277648-9kxwkcbl	143	2	directionality	directionality	NN
cord-277648-9kxwkcbl	143	3	of	of	IN
cord-277648-9kxwkcbl	143	4	these	these	DT
cord-277648-9kxwkcbl	143	5	genes	gene	NNS
cord-277648-9kxwkcbl	143	6	was	be	VBD
cord-277648-9kxwkcbl	143	7	observed	observe	VBN
cord-277648-9kxwkcbl	143	8	between	between	IN
cord-277648-9kxwkcbl	143	9	MPs	MPs	NNPS
cord-277648-9kxwkcbl	143	10	and	and	CC
cord-277648-9kxwkcbl	143	11	CD14	CD14	NNP
cord-277648-9kxwkcbl	143	12	+	+	CC
cord-277648-9kxwkcbl	143	13	monocytes	monocyte	NNS
cord-277648-9kxwkcbl	143	14	in	in	IN
cord-277648-9kxwkcbl	143	15	particular	particular	JJ
cord-277648-9kxwkcbl	143	16	.	.	.
cord-277648-9kxwkcbl	144	1	NELFE	NELFE	NNP
cord-277648-9kxwkcbl	144	2	appeared	appear	VBD
cord-277648-9kxwkcbl	144	3	to	to	TO
cord-277648-9kxwkcbl	144	4	be	be	VB
cord-277648-9kxwkcbl	144	5	enriched	enrich	VBN
cord-277648-9kxwkcbl	144	6	in	in	IN
cord-277648-9kxwkcbl	144	7	T	T	NNP
cord-277648-9kxwkcbl	144	8	cells	cell	NNS
cord-277648-9kxwkcbl	144	9	of	of	IN
cord-277648-9kxwkcbl	144	10	the	the	DT
cord-277648-9kxwkcbl	144	11	BALF	BALF	NNP
cord-277648-9kxwkcbl	144	12	and	and	CC
cord-277648-9kxwkcbl	144	13	PBMC	PBMC	NNP
cord-277648-9kxwkcbl	145	1	(	(	-LRB-
cord-277648-9kxwkcbl	145	2	Figure	figure	NN
cord-277648-9kxwkcbl	145	3	S3G	S3G	NNP
cord-277648-9kxwkcbl	145	4	-	-	HYPH
cord-277648-9kxwkcbl	145	5	H	H	NNP
cord-277648-9kxwkcbl	145	6	)	)	-RRB-
cord-277648-9kxwkcbl	145	7	,	,	,
cord-277648-9kxwkcbl	145	8	representing	represent	VBG
cord-277648-9kxwkcbl	145	9	a	a	DT
cord-277648-9kxwkcbl	145	10	commonality	commonality	NN
cord-277648-9kxwkcbl	145	11	between	between	IN
cord-277648-9kxwkcbl	145	12	the	the	DT
cord-277648-9kxwkcbl	145	13	lung	lung	NN
cord-277648-9kxwkcbl	145	14	and	and	CC
cord-277648-9kxwkcbl	145	15	blood	blood	NN
cord-277648-9kxwkcbl	145	16	responses	response	NNS
cord-277648-9kxwkcbl	145	17	to	to	IN
cord-277648-9kxwkcbl	145	18	increasing	increase	VBG
cord-277648-9kxwkcbl	145	19	disease	disease	NN
cord-277648-9kxwkcbl	145	20	severity	severity	NN
cord-277648-9kxwkcbl	145	21	.	.	.
cord-277648-9kxwkcbl	146	1	Following	follow	VBG
cord-277648-9kxwkcbl	146	2	the	the	DT
cord-277648-9kxwkcbl	146	3	identification	identification	NN
cord-277648-9kxwkcbl	146	4	of	of	IN
cord-277648-9kxwkcbl	146	5	severity	severity	NN
cord-277648-9kxwkcbl	146	6	-	-	HYPH
cord-277648-9kxwkcbl	146	7	specific	specific	JJ
cord-277648-9kxwkcbl	146	8	pathway	pathway	NN
cord-277648-9kxwkcbl	146	9	-	-	HYPH
cord-277648-9kxwkcbl	146	10	level	level	NN
cord-277648-9kxwkcbl	146	11	regulation	regulation	NN
cord-277648-9kxwkcbl	146	12	differentiating	differentiate	VBG
cord-277648-9kxwkcbl	146	13	severe	severe	JJ
cord-277648-9kxwkcbl	146	14	and	and	CC
cord-277648-9kxwkcbl	146	15	moderate	moderate	JJ
cord-277648-9kxwkcbl	146	16	disease	disease	NN
cord-277648-9kxwkcbl	146	17	courses	course	NNS
cord-277648-9kxwkcbl	146	18	,	,	,
cord-277648-9kxwkcbl	146	19	we	-PRON-	PRP
cord-277648-9kxwkcbl	146	20	sought	seek	VBD
cord-277648-9kxwkcbl	146	21	to	to	TO
cord-277648-9kxwkcbl	146	22	construct	construct	VB
cord-277648-9kxwkcbl	146	23	a	a	DT
cord-277648-9kxwkcbl	146	24	putative	putative	JJ
cord-277648-9kxwkcbl	146	25	network	network	NN
cord-277648-9kxwkcbl	146	26	for	for	IN
cord-277648-9kxwkcbl	146	27	how	how	WRB
cord-277648-9kxwkcbl	146	28	these	these	DT
cord-277648-9kxwkcbl	146	29	transcriptional	transcriptional	JJ
cord-277648-9kxwkcbl	146	30	programs	program	NNS
cord-277648-9kxwkcbl	146	31	could	could	MD
cord-277648-9kxwkcbl	146	32	be	be	VB
cord-277648-9kxwkcbl	146	33	induced	induce	VBN
cord-277648-9kxwkcbl	146	34	by	by	IN
cord-277648-9kxwkcbl	146	35	soluble	soluble	JJ
cord-277648-9kxwkcbl	146	36	and	and	CC
cord-277648-9kxwkcbl	146	37	surface	surface	NN
cord-277648-9kxwkcbl	146	38	-	-	HYPH
cord-277648-9kxwkcbl	146	39	level	level	NN
cord-277648-9kxwkcbl	146	40	cell	cell	NN
cord-277648-9kxwkcbl	146	41	-	-	HYPH
cord-277648-9kxwkcbl	146	42	cell	cell	NN
cord-277648-9kxwkcbl	146	43	interactions	interaction	NNS
cord-277648-9kxwkcbl	146	44	.	.	.
cord-277648-9kxwkcbl	147	1	Specifically	specifically	RB
cord-277648-9kxwkcbl	147	2	,	,	,
cord-277648-9kxwkcbl	147	3	we	-PRON-	PRP
cord-277648-9kxwkcbl	147	4	aimed	aim	VBD
cord-277648-9kxwkcbl	147	5	to	to	TO
cord-277648-9kxwkcbl	147	6	identify	identify	VB
cord-277648-9kxwkcbl	147	7	ligands	ligand	NNS
cord-277648-9kxwkcbl	147	8	acting	act	VBG
cord-277648-9kxwkcbl	147	9	as	as	IN
cord-277648-9kxwkcbl	147	10	potential	potential	JJ
cord-277648-9kxwkcbl	147	11	key	key	JJ
cord-277648-9kxwkcbl	147	12	regulators	regulator	NNS
cord-277648-9kxwkcbl	147	13	of	of	IN
cord-277648-9kxwkcbl	147	14	severe	severe	JJ
cord-277648-9kxwkcbl	147	15	disease	disease	NN
cord-277648-9kxwkcbl	147	16	in	in	IN
cord-277648-9kxwkcbl	147	17	many	many	JJ
cord-277648-9kxwkcbl	147	18	cell	cell	NN
cord-277648-9kxwkcbl	147	19	types	type	NNS
cord-277648-9kxwkcbl	147	20	of	of	IN
cord-277648-9kxwkcbl	147	21	the	the	DT
cord-277648-9kxwkcbl	147	22	lung	lung	NN
cord-277648-9kxwkcbl	147	23	in	in	IN
cord-277648-9kxwkcbl	147	24	order	order	NN
cord-277648-9kxwkcbl	147	25	to	to	TO
cord-277648-9kxwkcbl	147	26	nominate	nominate	VB
cord-277648-9kxwkcbl	147	27	targets	target	NNS
cord-277648-9kxwkcbl	147	28	for	for	IN
cord-277648-9kxwkcbl	147	29	further	further	JJ
cord-277648-9kxwkcbl	147	30	study	study	NN
cord-277648-9kxwkcbl	147	31	as	as	IN
cord-277648-9kxwkcbl	147	32	therapeutic	therapeutic	JJ
cord-277648-9kxwkcbl	147	33	options	option	NNS
cord-277648-9kxwkcbl	147	34	for	for	IN
cord-277648-9kxwkcbl	147	35	severe	severe	JJ
cord-277648-9kxwkcbl	147	36	COVID-19	covid-19	NN
cord-277648-9kxwkcbl	147	37	.	.	.
cord-277648-9kxwkcbl	148	1	Figure	figure	NN
cord-277648-9kxwkcbl	148	2	4A	4a	CD
cord-277648-9kxwkcbl	148	3	shows	show	VBZ
cord-277648-9kxwkcbl	148	4	a	a	DT
cord-277648-9kxwkcbl	148	5	flow	flow	NN
cord-277648-9kxwkcbl	148	6	diagram	diagram	NN
cord-277648-9kxwkcbl	148	7	detailing	detail	VBG
cord-277648-9kxwkcbl	148	8	the	the	DT
cord-277648-9kxwkcbl	148	9	steps	step	NNS
cord-277648-9kxwkcbl	148	10	carried	carry	VBN
cord-277648-9kxwkcbl	148	11	out	out	RP
cord-277648-9kxwkcbl	148	12	to	to	TO
cord-277648-9kxwkcbl	148	13	nominate	nominate	VB
cord-277648-9kxwkcbl	148	14	severity	severity	NN
cord-277648-9kxwkcbl	148	15	-	-	HYPH
cord-277648-9kxwkcbl	148	16	specific	specific	JJ
cord-277648-9kxwkcbl	148	17	"	"	``
cord-277648-9kxwkcbl	148	18	pan	pan	NN
cord-277648-9kxwkcbl	148	19	-	-	HYPH
cord-277648-9kxwkcbl	148	20	ligands	ligand	NNS
cord-277648-9kxwkcbl	148	21	"	"	''
cord-277648-9kxwkcbl	148	22	local	local	JJ
cord-277648-9kxwkcbl	148	23	to	to	IN
cord-277648-9kxwkcbl	148	24	the	the	DT
cord-277648-9kxwkcbl	148	25	site	site	NN
cord-277648-9kxwkcbl	148	26	of	of	IN
cord-277648-9kxwkcbl	148	27	viral	viral	JJ
cord-277648-9kxwkcbl	148	28	infection	infection	NN
cord-277648-9kxwkcbl	148	29	.	.	.
cord-277648-9kxwkcbl	149	1	Briefly	briefly	RB
cord-277648-9kxwkcbl	149	2	,	,	,
cord-277648-9kxwkcbl	149	3	differential	differential	JJ
cord-277648-9kxwkcbl	149	4	gene	gene	NN
cord-277648-9kxwkcbl	149	5	expression	expression	NN
cord-277648-9kxwkcbl	149	6	between	between	IN
cord-277648-9kxwkcbl	149	7	moderate	moderate	JJ
cord-277648-9kxwkcbl	149	8	and	and	CC
cord-277648-9kxwkcbl	149	9	severe	severe	JJ
cord-277648-9kxwkcbl	149	10	donors	donor	NNS
cord-277648-9kxwkcbl	149	11	was	be	VBD
cord-277648-9kxwkcbl	149	12	first	first	RB
cord-277648-9kxwkcbl	149	13	evaluated	evaluate	VBN
cord-277648-9kxwkcbl	149	14	for	for	IN
cord-277648-9kxwkcbl	149	15	each	each	DT
cord-277648-9kxwkcbl	149	16	cell	cell	NN
cord-277648-9kxwkcbl	149	17	type	type	NN
cord-277648-9kxwkcbl	149	18	in	in	IN
cord-277648-9kxwkcbl	149	19	the	the	DT
cord-277648-9kxwkcbl	149	20	BALF	BALF	NNP
cord-277648-9kxwkcbl	149	21	.	.	.
cord-277648-9kxwkcbl	150	1	We	-PRON-	PRP
cord-277648-9kxwkcbl	150	2	classified	classify	VBD
cord-277648-9kxwkcbl	150	3	these	these	DT
cord-277648-9kxwkcbl	150	4	transcripts	transcript	NNS
cord-277648-9kxwkcbl	150	5	as	as	IN
cord-277648-9kxwkcbl	150	6	"	"	``
cord-277648-9kxwkcbl	150	7	target	target	NN
cord-277648-9kxwkcbl	150	8	genes	gene	NNS
cord-277648-9kxwkcbl	150	9	"	"	''
cord-277648-9kxwkcbl	150	10	whose	whose	WP$
cord-277648-9kxwkcbl	150	11	differential	differential	JJ
cord-277648-9kxwkcbl	150	12	expression	expression	NN
cord-277648-9kxwkcbl	150	13	is	be	VBZ
cord-277648-9kxwkcbl	150	14	potentially	potentially	RB
cord-277648-9kxwkcbl	150	15	regulated	regulate	VBN
cord-277648-9kxwkcbl	150	16	through	through	IN
cord-277648-9kxwkcbl	150	17	ligand	ligand	NN
cord-277648-9kxwkcbl	150	18	-	-	HYPH
cord-277648-9kxwkcbl	150	19	receptor	receptor	NN
cord-277648-9kxwkcbl	150	20	interactions	interaction	NNS
cord-277648-9kxwkcbl	150	21	[	[	-LRB-
cord-277648-9kxwkcbl	150	22	37	37	CD
cord-277648-9kxwkcbl	150	23	]	]	-RRB-
cord-277648-9kxwkcbl	150	24	.	.	.
cord-277648-9kxwkcbl	151	1	Next	next	RB
cord-277648-9kxwkcbl	151	2	,	,	,
cord-277648-9kxwkcbl	151	3	we	-PRON-	PRP
cord-277648-9kxwkcbl	151	4	employed	employ	VBD
cord-277648-9kxwkcbl	151	5	NicheNet	NicheNet	NNP
cord-277648-9kxwkcbl	151	6	to	to	TO
cord-277648-9kxwkcbl	151	7	identify	identify	VB
cord-277648-9kxwkcbl	151	8	potential	potential	JJ
cord-277648-9kxwkcbl	151	9	ligands	ligand	NNS
cord-277648-9kxwkcbl	151	10	linked	link	VBN
cord-277648-9kxwkcbl	151	11	to	to	IN
cord-277648-9kxwkcbl	151	12	regulation	regulation	NN
cord-277648-9kxwkcbl	151	13	of	of	IN
cord-277648-9kxwkcbl	151	14	these	these	DT
cord-277648-9kxwkcbl	151	15	differentially	differentially	RB
cord-277648-9kxwkcbl	151	16	expressed	express	VBN
cord-277648-9kxwkcbl	151	17	target	target	NN
cord-277648-9kxwkcbl	151	18	genes	gene	NNS
cord-277648-9kxwkcbl	151	19	[	[	-LRB-
cord-277648-9kxwkcbl	151	20	37	37	CD
cord-277648-9kxwkcbl	151	21	]	]	-RRB-
cord-277648-9kxwkcbl	151	22	.	.	.
cord-277648-9kxwkcbl	152	1	We	-PRON-	PRP
cord-277648-9kxwkcbl	152	2	applied	apply	VBD
cord-277648-9kxwkcbl	152	3	two	two	CD
cord-277648-9kxwkcbl	152	4	filtering	filter	VBG
cord-277648-9kxwkcbl	152	5	criteria	criterion	NNS
cord-277648-9kxwkcbl	152	6	to	to	TO
cord-277648-9kxwkcbl	152	7	nominate	nominate	VB
cord-277648-9kxwkcbl	152	8	potential	potential	JJ
cord-277648-9kxwkcbl	152	9	ligands	ligand	NNS
cord-277648-9kxwkcbl	152	10	:	:	:
cord-277648-9kxwkcbl	152	11	Ligands	Ligands	NNP
cord-277648-9kxwkcbl	152	12	should	should	MD
cord-277648-9kxwkcbl	152	13	(	(	-LRB-
cord-277648-9kxwkcbl	152	14	1	1	LS
cord-277648-9kxwkcbl	152	15	)	)	-RRB-
cord-277648-9kxwkcbl	152	16	act	act	VB
cord-277648-9kxwkcbl	152	17	on	on	RP
cord-277648-9kxwkcbl	152	18	over	over	IN
cord-277648-9kxwkcbl	152	19	one	one	CD
cord-277648-9kxwkcbl	152	20	-	-	HYPH
cord-277648-9kxwkcbl	152	21	third	third	NN
cord-277648-9kxwkcbl	152	22	of	of	IN
cord-277648-9kxwkcbl	152	23	the	the	DT
cord-277648-9kxwkcbl	152	24	cell	cell	NN
cord-277648-9kxwkcbl	152	25	types	type	NNS
cord-277648-9kxwkcbl	152	26	in	in	IN
cord-277648-9kxwkcbl	152	27	the	the	DT
cord-277648-9kxwkcbl	152	28	BALF	BALF	NNP
cord-277648-9kxwkcbl	153	1	and	and	CC
cord-277648-9kxwkcbl	153	2	(	(	-LRB-
cord-277648-9kxwkcbl	153	3	2	2	LS
cord-277648-9kxwkcbl	153	4	)	)	-RRB-
cord-277648-9kxwkcbl	153	5	be	be	VB
cord-277648-9kxwkcbl	153	6	differentially	differentially	RB
cord-277648-9kxwkcbl	153	7	expressed	express	VBN
cord-277648-9kxwkcbl	153	8	by	by	IN
cord-277648-9kxwkcbl	153	9	at	at	RB
cord-277648-9kxwkcbl	153	10	least	least	RBS
cord-277648-9kxwkcbl	153	11	one	one	CD
cord-277648-9kxwkcbl	153	12	cell	cell	NN
cord-277648-9kxwkcbl	153	13	type	type	NN
cord-277648-9kxwkcbl	153	14	in	in	IN
cord-277648-9kxwkcbl	153	15	severe	severe	JJ
cord-277648-9kxwkcbl	153	16	disease	disease	NN
cord-277648-9kxwkcbl	153	17	.	.	.
cord-277648-9kxwkcbl	154	1	To	to	TO
cord-277648-9kxwkcbl	154	2	follow	follow	VB
cord-277648-9kxwkcbl	154	3	up	up	RP
cord-277648-9kxwkcbl	154	4	on	on	IN
cord-277648-9kxwkcbl	154	5	our	-PRON-	PRP$
cord-277648-9kxwkcbl	154	6	observation	observation	NN
cord-277648-9kxwkcbl	154	7	of	of	IN
cord-277648-9kxwkcbl	154	8	AREG	AREG	NNP
cord-277648-9kxwkcbl	154	9	upregulation	upregulation	NN
cord-277648-9kxwkcbl	154	10	in	in	IN
cord-277648-9kxwkcbl	154	11	pDCs	pDCs	NNP
cord-277648-9kxwkcbl	154	12	during	during	IN
cord-277648-9kxwkcbl	154	13	severe	severe	JJ
cord-277648-9kxwkcbl	154	14	disease	disease	NN
cord-277648-9kxwkcbl	154	15	,	,	,
cord-277648-9kxwkcbl	154	16	we	-PRON-	PRP
cord-277648-9kxwkcbl	154	17	used	use	VBD
cord-277648-9kxwkcbl	154	18	NicheNet	NicheNet	NNP
cord-277648-9kxwkcbl	154	19	to	to	TO
cord-277648-9kxwkcbl	154	20	nominate	nominate	VB
cord-277648-9kxwkcbl	154	21	potential	potential	JJ
cord-277648-9kxwkcbl	154	22	soluble	soluble	JJ
cord-277648-9kxwkcbl	154	23	or	or	CC
cord-277648-9kxwkcbl	154	24	cell	cell	NN
cord-277648-9kxwkcbl	154	25	-	-	HYPH
cord-277648-9kxwkcbl	154	26	surface	surface	NN
cord-277648-9kxwkcbl	154	27	mediators	mediator	NNS
cord-277648-9kxwkcbl	154	28	of	of	IN
cord-277648-9kxwkcbl	154	29	pDC	pDC	NNP
cord-277648-9kxwkcbl	154	30	differential	differential	JJ
cord-277648-9kxwkcbl	154	31	gene	gene	NN
cord-277648-9kxwkcbl	154	32	expression	expression	NN
cord-277648-9kxwkcbl	154	33	.	.	.
cord-277648-9kxwkcbl	155	1	Ligand	ligand	NN
cord-277648-9kxwkcbl	155	2	activities	activity	NNS
cord-277648-9kxwkcbl	155	3	were	be	VBD
cord-277648-9kxwkcbl	155	4	ranked	rank	VBN
cord-277648-9kxwkcbl	155	5	using	use	VBG
cord-277648-9kxwkcbl	155	6	a	a	DT
cord-277648-9kxwkcbl	155	7	NicheNet	NicheNet	NNP
cord-277648-9kxwkcbl	155	8	-	-	HYPH
cord-277648-9kxwkcbl	155	9	generated	generate	VBN
cord-277648-9kxwkcbl	155	10	Pearson	Pearson	NNP
cord-277648-9kxwkcbl	155	11	correlation	correlation	NN
cord-277648-9kxwkcbl	155	12	coefficient	coefficient	NN
cord-277648-9kxwkcbl	155	13	indicating	indicate	VBG
cord-277648-9kxwkcbl	155	14	the	the	DT
cord-277648-9kxwkcbl	155	15	correlation	correlation	NN
cord-277648-9kxwkcbl	155	16	between	between	IN
cord-277648-9kxwkcbl	155	17	the	the	DT
cord-277648-9kxwkcbl	155	18	target	target	NN
cord-277648-9kxwkcbl	155	19	genes	gene	NNS
cord-277648-9kxwkcbl	155	20	of	of	IN
cord-277648-9kxwkcbl	155	21	a	a	DT
cord-277648-9kxwkcbl	155	22	given	give	VBN
cord-277648-9kxwkcbl	155	23	ligand	ligand	NN
cord-277648-9kxwkcbl	155	24	and	and	CC
cord-277648-9kxwkcbl	155	25	the	the	DT
cord-277648-9kxwkcbl	155	26	list	list	NN
cord-277648-9kxwkcbl	155	27	of	of	IN
cord-277648-9kxwkcbl	155	28	differentially	differentially	RB
cord-277648-9kxwkcbl	155	29	expressed	express	VBN
cord-277648-9kxwkcbl	155	30	target	target	NN
cord-277648-9kxwkcbl	155	31	genes	gene	NNS
cord-277648-9kxwkcbl	155	32	in	in	IN
cord-277648-9kxwkcbl	155	33	the	the	DT
cord-277648-9kxwkcbl	155	34	"	"	``
cord-277648-9kxwkcbl	155	35	receiver	receiver	NN
cord-277648-9kxwkcbl	155	36	"	"	''
cord-277648-9kxwkcbl	155	37	cell	cell	NN
cord-277648-9kxwkcbl	155	38	(	(	-LRB-
cord-277648-9kxwkcbl	155	39	Figure	figure	NN
cord-277648-9kxwkcbl	155	40	4B	4b	NN
cord-277648-9kxwkcbl	155	41	)	)	-RRB-
cord-277648-9kxwkcbl	155	42	.	.	.
cord-277648-9kxwkcbl	156	1	The	the	DT
cord-277648-9kxwkcbl	156	2	receptors	receptor	NNS
cord-277648-9kxwkcbl	156	3	for	for	IN
cord-277648-9kxwkcbl	156	4	the	the	DT
cord-277648-9kxwkcbl	156	5	top	top	JJ
cord-277648-9kxwkcbl	156	6	predicted	predict	VBN
cord-277648-9kxwkcbl	156	7	ligands	ligand	NNS
cord-277648-9kxwkcbl	156	8	ANXA1	ANXA1	NNS
cord-277648-9kxwkcbl	156	9	,	,	,
cord-277648-9kxwkcbl	156	10	SPP1	SPP1	NNP
cord-277648-9kxwkcbl	156	11	,	,	,
cord-277648-9kxwkcbl	156	12	TNF	TNF	NNP
cord-277648-9kxwkcbl	156	13	,	,	,
cord-277648-9kxwkcbl	156	14	CSF	CSF	NNP
cord-277648-9kxwkcbl	156	15	,	,	,
cord-277648-9kxwkcbl	156	16	CXCL9	CXCL9	NNP
cord-277648-9kxwkcbl	156	17	,	,	,
cord-277648-9kxwkcbl	156	18	IFNG	IFNG	NNP
cord-277648-9kxwkcbl	156	19	,	,	,
cord-277648-9kxwkcbl	156	20	CD40LG	CD40LG	NNP
cord-277648-9kxwkcbl	156	21	,	,	,
cord-277648-9kxwkcbl	156	22	ITGB2	itgb2	NN
cord-277648-9kxwkcbl	156	23	,	,	,
cord-277648-9kxwkcbl	156	24	CD28	CD28	NNP
cord-277648-9kxwkcbl	156	25	,	,	,
cord-277648-9kxwkcbl	156	26	ICAM1	ICAM1	NNP
cord-277648-9kxwkcbl	156	27	,	,	,
cord-277648-9kxwkcbl	156	28	ADM	ADM	NNP
cord-277648-9kxwkcbl	156	29	,	,	,
cord-277648-9kxwkcbl	156	30	and	and	CC
cord-277648-9kxwkcbl	156	31	IL18	IL18	NNP
cord-277648-9kxwkcbl	156	32	all	all	DT
cord-277648-9kxwkcbl	156	33	showed	show	VBD
cord-277648-9kxwkcbl	156	34	non	non	JJ
cord-277648-9kxwkcbl	156	35	-	-	JJ
cord-277648-9kxwkcbl	156	36	zero	zero	JJ
cord-277648-9kxwkcbl	156	37	expression	expression	NN
cord-277648-9kxwkcbl	156	38	in	in	IN
cord-277648-9kxwkcbl	156	39	pDCs	pDCs	NNP
cord-277648-9kxwkcbl	156	40	.	.	.
cord-277648-9kxwkcbl	157	1	To	to	TO
cord-277648-9kxwkcbl	157	2	identify	identify	VB
cord-277648-9kxwkcbl	157	3	which	which	WDT
cord-277648-9kxwkcbl	157	4	genes	gene	NNS
cord-277648-9kxwkcbl	157	5	may	may	MD
cord-277648-9kxwkcbl	157	6	be	be	VB
cord-277648-9kxwkcbl	157	7	regulated	regulate	VBN
cord-277648-9kxwkcbl	157	8	by	by	IN
cord-277648-9kxwkcbl	157	9	top	top	RB
cord-277648-9kxwkcbl	157	10	-	-	HYPH
cord-277648-9kxwkcbl	157	11	ranked	rank	VBN
cord-277648-9kxwkcbl	157	12	ligands	ligand	NNS
cord-277648-9kxwkcbl	157	13	,	,	,
cord-277648-9kxwkcbl	157	14	putative	putative	JJ
cord-277648-9kxwkcbl	157	15	ligand	ligand	NN
cord-277648-9kxwkcbl	157	16	-	-	HYPH
cord-277648-9kxwkcbl	157	17	gene	gene	NN
cord-277648-9kxwkcbl	157	18	interactions	interaction	NNS
cord-277648-9kxwkcbl	157	19	were	be	VBD
cord-277648-9kxwkcbl	157	20	scored	score	VBN
cord-277648-9kxwkcbl	157	21	by	by	IN
cord-277648-9kxwkcbl	157	22	NicheNet	NicheNet	NNP
cord-277648-9kxwkcbl	157	23	according	accord	VBG
cord-277648-9kxwkcbl	157	24	to	to	IN
cord-277648-9kxwkcbl	157	25	"	"	``
cord-277648-9kxwkcbl	157	26	regulatory	regulatory	JJ
cord-277648-9kxwkcbl	157	27	potential	potential	NN
cord-277648-9kxwkcbl	157	28	"	"	''
cord-277648-9kxwkcbl	157	29	,	,	,
cord-277648-9kxwkcbl	157	30	a	a	DT
cord-277648-9kxwkcbl	157	31	graph	graph	NN
cord-277648-9kxwkcbl	157	32	-	-	HYPH
cord-277648-9kxwkcbl	157	33	based	base	VBN
cord-277648-9kxwkcbl	157	34	likelihood	likelihood	NN
cord-277648-9kxwkcbl	157	35	for	for	IN
cord-277648-9kxwkcbl	157	36	a	a	DT
cord-277648-9kxwkcbl	157	37	ligand	ligand	NN
cord-277648-9kxwkcbl	157	38	to	to	TO
cord-277648-9kxwkcbl	157	39	regulate	regulate	VB
cord-277648-9kxwkcbl	157	40	a	a	DT
cord-277648-9kxwkcbl	157	41	particular	particular	JJ
cord-277648-9kxwkcbl	157	42	target	target	NN
cord-277648-9kxwkcbl	157	43	gene	gene	NN
cord-277648-9kxwkcbl	157	44	[	[	-LRB-
cord-277648-9kxwkcbl	157	45	37	37	CD
cord-277648-9kxwkcbl	157	46	]	]	-RRB-
cord-277648-9kxwkcbl	157	47	.	.	.
cord-277648-9kxwkcbl	158	1	We	-PRON-	PRP
cord-277648-9kxwkcbl	158	2	next	next	RB
cord-277648-9kxwkcbl	158	3	sought	seek	VBD
cord-277648-9kxwkcbl	158	4	to	to	TO
cord-277648-9kxwkcbl	158	5	identify	identify	VB
cord-277648-9kxwkcbl	158	6	candidate	candidate	NN
cord-277648-9kxwkcbl	158	7	"	"	''
cord-277648-9kxwkcbl	158	8	sender	sender	NN
cord-277648-9kxwkcbl	158	9	cells	cell	NNS
cord-277648-9kxwkcbl	158	10	"	"	''
cord-277648-9kxwkcbl	158	11	expressing	express	VBG
cord-277648-9kxwkcbl	158	12	these	these	DT
cord-277648-9kxwkcbl	158	13	ligands	ligand	NNS
cord-277648-9kxwkcbl	158	14	(	(	-LRB-
cord-277648-9kxwkcbl	158	15	Figure	figure	NN
cord-277648-9kxwkcbl	158	16	S4A	s4a	NN
cord-277648-9kxwkcbl	158	17	)	)	-RRB-
cord-277648-9kxwkcbl	158	18	.	.	.
cord-277648-9kxwkcbl	159	1	We	-PRON-	PRP
cord-277648-9kxwkcbl	159	2	found	find	VBD
cord-277648-9kxwkcbl	159	3	that	that	IN
cord-277648-9kxwkcbl	159	4	MPs	mp	NNS
cord-277648-9kxwkcbl	159	5	and	and	CC
cord-277648-9kxwkcbl	159	6	neutrophils	neutrophil	NNS
cord-277648-9kxwkcbl	159	7	expressed	express	VBD
cord-277648-9kxwkcbl	159	8	transcripts	transcript	NNS
cord-277648-9kxwkcbl	159	9	for	for	IN
cord-277648-9kxwkcbl	159	10	pDC	pDC	NNP
cord-277648-9kxwkcbl	159	11	ligands	ligand	NNS
cord-277648-9kxwkcbl	159	12	,	,	,
cord-277648-9kxwkcbl	159	13	and	and	CC
cord-277648-9kxwkcbl	159	14	we	-PRON-	PRP
cord-277648-9kxwkcbl	159	15	chose	choose	VBD
cord-277648-9kxwkcbl	159	16	to	to	TO
cord-277648-9kxwkcbl	159	17	further	further	RB
cord-277648-9kxwkcbl	159	18	investigate	investigate	VB
cord-277648-9kxwkcbl	159	19	these	these	DT
cord-277648-9kxwkcbl	159	20	relationships	relationship	NNS
cord-277648-9kxwkcbl	159	21	.	.	.
cord-277648-9kxwkcbl	160	1	Ligand	ligand	NN
cord-277648-9kxwkcbl	160	2	-	-	HYPH
cord-277648-9kxwkcbl	160	3	mediated	mediate	VBN
cord-277648-9kxwkcbl	160	4	cell	cell	NN
cord-277648-9kxwkcbl	160	5	-	-	HYPH
cord-277648-9kxwkcbl	160	6	cell	cell	NN
cord-277648-9kxwkcbl	160	7	interactions	interaction	NNS
cord-277648-9kxwkcbl	160	8	between	between	IN
cord-277648-9kxwkcbl	160	9	MPs	mp	NNS
cord-277648-9kxwkcbl	160	10	,	,	,
cord-277648-9kxwkcbl	160	11	neutrophils	neutrophil	NNS
cord-277648-9kxwkcbl	160	12	,	,	,
cord-277648-9kxwkcbl	160	13	and	and	CC
cord-277648-9kxwkcbl	160	14	pDCs	pdcs	PRP
cord-277648-9kxwkcbl	160	15	are	be	VBP
cord-277648-9kxwkcbl	160	16	visualized	visualize	VBN
cord-277648-9kxwkcbl	160	17	in	in	IN
cord-277648-9kxwkcbl	160	18	the	the	DT
cord-277648-9kxwkcbl	160	19	network	network	NN
cord-277648-9kxwkcbl	160	20	diagram	diagram	NN
cord-277648-9kxwkcbl	160	21	in	in	IN
cord-277648-9kxwkcbl	160	22	Figure	figure	NN
cord-277648-9kxwkcbl	160	23	4B	4b	NN
cord-277648-9kxwkcbl	160	24	.	.	.
cord-277648-9kxwkcbl	161	1	As	as	IN
cord-277648-9kxwkcbl	161	2	shown	show	VBN
cord-277648-9kxwkcbl	161	3	,	,	,
cord-277648-9kxwkcbl	161	4	the	the	DT
cord-277648-9kxwkcbl	161	5	differential	differential	JJ
cord-277648-9kxwkcbl	161	6	expression	expression	NN
cord-277648-9kxwkcbl	161	7	of	of	IN
cord-277648-9kxwkcbl	161	8	AREG	AREG	NNP
cord-277648-9kxwkcbl	161	9	is	be	VBZ
cord-277648-9kxwkcbl	161	10	potentially	potentially	RB
cord-277648-9kxwkcbl	161	11	regulated	regulate	VBN
cord-277648-9kxwkcbl	161	12	by	by	IN
cord-277648-9kxwkcbl	161	13	IL-6	IL-6	NNP
cord-277648-9kxwkcbl	161	14	and	and	CC
cord-277648-9kxwkcbl	161	15	SPP1	SPP1	NNPS
cord-277648-9kxwkcbl	161	16	from	from	IN
cord-277648-9kxwkcbl	161	17	MPs	MPs	NNPS
cord-277648-9kxwkcbl	161	18	,	,	,
cord-277648-9kxwkcbl	161	19	and	and	CC
cord-277648-9kxwkcbl	161	20	IL1-β	IL1-β	NNPS
cord-277648-9kxwkcbl	161	21	from	from	IN
cord-277648-9kxwkcbl	161	22	neutrophils	neutrophil	NNS
cord-277648-9kxwkcbl	161	23	,	,	,
cord-277648-9kxwkcbl	161	24	although	although	IN
cord-277648-9kxwkcbl	161	25	the	the	DT
cord-277648-9kxwkcbl	161	26	receptors	receptor	NNS
cord-277648-9kxwkcbl	161	27	for	for	IN
cord-277648-9kxwkcbl	161	28	IL-6	IL-6	NNP
cord-277648-9kxwkcbl	161	29	and	and	CC
cord-277648-9kxwkcbl	161	30	IL1-β	IL1-β	NNPS
cord-277648-9kxwkcbl	161	31	could	could	MD
cord-277648-9kxwkcbl	161	32	not	not	RB
cord-277648-9kxwkcbl	161	33	be	be	VB
cord-277648-9kxwkcbl	161	34	verified	verify	VBN
cord-277648-9kxwkcbl	161	35	at	at	IN
cord-277648-9kxwkcbl	161	36	the	the	DT
cord-277648-9kxwkcbl	161	37	transcript	transcript	NN
cord-277648-9kxwkcbl	161	38	level	level	NN
cord-277648-9kxwkcbl	161	39	in	in	IN
cord-277648-9kxwkcbl	161	40	pDCs	pDCs	NNP
cord-277648-9kxwkcbl	161	41	in	in	IN
cord-277648-9kxwkcbl	161	42	our	-PRON-	PRP$
cord-277648-9kxwkcbl	161	43	dataset	dataset	NN
cord-277648-9kxwkcbl	161	44	.	.	.
cord-277648-9kxwkcbl	162	1	Additionally	additionally	RB
cord-277648-9kxwkcbl	162	2	,	,	,
cord-277648-9kxwkcbl	162	3	given	give	VBN
cord-277648-9kxwkcbl	162	4	the	the	DT
cord-277648-9kxwkcbl	162	5	enrichment	enrichment	NN
cord-277648-9kxwkcbl	162	6	of	of	IN
cord-277648-9kxwkcbl	162	7	oncogenic	oncogenic	JJ
cord-277648-9kxwkcbl	162	8	pathways	pathway	NNS
cord-277648-9kxwkcbl	162	9	in	in	IN
cord-277648-9kxwkcbl	162	10	epithelial	epithelial	JJ
cord-277648-9kxwkcbl	162	11	cells	cell	NNS
cord-277648-9kxwkcbl	162	12	of	of	IN
cord-277648-9kxwkcbl	162	13	the	the	DT
cord-277648-9kxwkcbl	162	14	BALF	BALF	NNP
cord-277648-9kxwkcbl	162	15	,	,	,
cord-277648-9kxwkcbl	162	16	we	-PRON-	PRP
cord-277648-9kxwkcbl	162	17	identified	identify	VBD
cord-277648-9kxwkcbl	162	18	cell	cell	NN
cord-277648-9kxwkcbl	162	19	types	type	NNS
cord-277648-9kxwkcbl	162	20	and	and	CC
cord-277648-9kxwkcbl	162	21	signaling	signal	VBG
cord-277648-9kxwkcbl	162	22	molecules	molecule	NNS
cord-277648-9kxwkcbl	162	23	potentially	potentially	RB
cord-277648-9kxwkcbl	162	24	regulating	regulate	VBG
cord-277648-9kxwkcbl	162	25	epithelial	epithelial	JJ
cord-277648-9kxwkcbl	162	26	DEGs	deg	NNS
cord-277648-9kxwkcbl	162	27	.	.	.
cord-277648-9kxwkcbl	163	1	We	-PRON-	PRP
cord-277648-9kxwkcbl	163	2	applied	apply	VBD
cord-277648-9kxwkcbl	163	3	the	the	DT
cord-277648-9kxwkcbl	163	4	NicheNet	NicheNet	NNP
cord-277648-9kxwkcbl	163	5	procedure	procedure	NN
cord-277648-9kxwkcbl	163	6	outlined	outline	VBN
cord-277648-9kxwkcbl	163	7	above	above	RB
cord-277648-9kxwkcbl	163	8	for	for	IN
cord-277648-9kxwkcbl	163	9	pDCs	pDCs	NNP
cord-277648-9kxwkcbl	163	10	to	to	IN
cord-277648-9kxwkcbl	163	11	club	club	NN
cord-277648-9kxwkcbl	163	12	and	and	CC
cord-277648-9kxwkcbl	163	13	ciliated	ciliated	JJ
cord-277648-9kxwkcbl	163	14	cells	cell	NNS
cord-277648-9kxwkcbl	163	15	of	of	IN
cord-277648-9kxwkcbl	163	16	the	the	DT
cord-277648-9kxwkcbl	163	17	BALF	BALF	NNP
cord-277648-9kxwkcbl	163	18	,	,	,
cord-277648-9kxwkcbl	163	19	resulting	result	VBG
cord-277648-9kxwkcbl	163	20	in	in	IN
cord-277648-9kxwkcbl	163	21	the	the	DT
cord-277648-9kxwkcbl	163	22	ligandgene	ligandgene	JJ
cord-277648-9kxwkcbl	163	23	regulatory	regulatory	JJ
cord-277648-9kxwkcbl	163	24	matrix	matrix	NN
cord-277648-9kxwkcbl	163	25	shown	show	VBN
cord-277648-9kxwkcbl	163	26	in	in	IN
cord-277648-9kxwkcbl	163	27	Figure	Figure	NNP
cord-277648-9kxwkcbl	163	28	4C	4c	CD
cord-277648-9kxwkcbl	163	29	.	.	.
cord-277648-9kxwkcbl	164	1	The	the	DT
cord-277648-9kxwkcbl	164	2	ligands	ligand	NNS
cord-277648-9kxwkcbl	164	3	IL1B	il1b	NN
cord-277648-9kxwkcbl	164	4	,	,	,
cord-277648-9kxwkcbl	164	5	IL1A	IL1A	NNP
cord-277648-9kxwkcbl	164	6	,	,	,
cord-277648-9kxwkcbl	164	7	TNF	TNF	NNP
cord-277648-9kxwkcbl	164	8	,	,	,
cord-277648-9kxwkcbl	164	9	IFNG	IFNG	NNP
cord-277648-9kxwkcbl	164	10	,	,	,
cord-277648-9kxwkcbl	164	11	APOE	APOE	NNP
cord-277648-9kxwkcbl	164	12	,	,	,
cord-277648-9kxwkcbl	164	13	IL1RN	IL1RN	NNP
cord-277648-9kxwkcbl	164	14	,	,	,
cord-277648-9kxwkcbl	164	15	OSM	OSM	NNP
cord-277648-9kxwkcbl	164	16	,	,	,
cord-277648-9kxwkcbl	164	17	  	  	_SP
cord-277648-9kxwkcbl	164	18	EDN1	EDN1	NNP
cord-277648-9kxwkcbl	164	19	,	,	,
cord-277648-9kxwkcbl	164	20	LIF	LIF	NNP
cord-277648-9kxwkcbl	164	21	,	,	,
cord-277648-9kxwkcbl	164	22	MIF	MIF	NNP
cord-277648-9kxwkcbl	164	23	,	,	,
cord-277648-9kxwkcbl	164	24	CSF2	CSF2	NNP
cord-277648-9kxwkcbl	164	25	,	,	,
cord-277648-9kxwkcbl	164	26	SPP1	SPP1	NNPS
cord-277648-9kxwkcbl	164	27	,	,	,
cord-277648-9kxwkcbl	164	28	CD28	CD28	NNP
cord-277648-9kxwkcbl	164	29	,	,	,
cord-277648-9kxwkcbl	164	30	CCL2	CCL2	NNP
cord-277648-9kxwkcbl	164	31	,	,	,
cord-277648-9kxwkcbl	164	32	VEGFA	VEGFA	NNP
cord-277648-9kxwkcbl	164	33	,	,	,
cord-277648-9kxwkcbl	164	34	and	and	CC
cord-277648-9kxwkcbl	164	35	CCL5	CCL5	NNP
cord-277648-9kxwkcbl	164	36	show	show	VBP
cord-277648-9kxwkcbl	164	37	potential	potential	NN
cord-277648-9kxwkcbl	164	38	for	for	IN
cord-277648-9kxwkcbl	164	39	regulating	regulate	VBG
cord-277648-9kxwkcbl	164	40	differential	differential	JJ
cord-277648-9kxwkcbl	164	41	expression	expression	NN
cord-277648-9kxwkcbl	164	42	,	,	,
cord-277648-9kxwkcbl	164	43	and	and	CC
cord-277648-9kxwkcbl	164	44	receptors	receptor	NNS
cord-277648-9kxwkcbl	164	45	for	for	IN
cord-277648-9kxwkcbl	164	46	all	all	DT
cord-277648-9kxwkcbl	164	47	of	of	IN
cord-277648-9kxwkcbl	164	48	these	these	DT
cord-277648-9kxwkcbl	164	49	ligands	ligand	NNS
cord-277648-9kxwkcbl	164	50	were	be	VBD
cord-277648-9kxwkcbl	164	51	manually	manually	RB
cord-277648-9kxwkcbl	164	52	verified	verify	VBN
cord-277648-9kxwkcbl	164	53	at	at	IN
cord-277648-9kxwkcbl	164	54	the	the	DT
cord-277648-9kxwkcbl	164	55	transcript	transcript	NN
cord-277648-9kxwkcbl	164	56	level	level	NN
cord-277648-9kxwkcbl	164	57	in	in	IN
cord-277648-9kxwkcbl	164	58	club	club	NN
cord-277648-9kxwkcbl	164	59	or	or	CC
cord-277648-9kxwkcbl	164	60	ciliated	ciliated	JJ
cord-277648-9kxwkcbl	164	61	cells	cell	NNS
cord-277648-9kxwkcbl	164	62	.	.	.
cord-277648-9kxwkcbl	165	1	Interestingly	interestingly	RB
cord-277648-9kxwkcbl	165	2	,	,	,
cord-277648-9kxwkcbl	165	3	FOS	FOS	NNP
cord-277648-9kxwkcbl	165	4	and	and	CC
cord-277648-9kxwkcbl	165	5	JUN	JUN	NNP
cord-277648-9kxwkcbl	165	6	are	be	VBP
cord-277648-9kxwkcbl	165	7	among	among	IN
cord-277648-9kxwkcbl	165	8	the	the	DT
cord-277648-9kxwkcbl	165	9	genes	gene	NNS
cord-277648-9kxwkcbl	165	10	potentially	potentially	RB
cord-277648-9kxwkcbl	165	11	driven	drive	VBN
cord-277648-9kxwkcbl	165	12	by	by	IN
cord-277648-9kxwkcbl	165	13	the	the	DT
cord-277648-9kxwkcbl	165	14	proposed	propose	VBN
cord-277648-9kxwkcbl	165	15	ligands	ligand	NNS
cord-277648-9kxwkcbl	165	16	.	.	.
cord-277648-9kxwkcbl	166	1	As	as	IN
cord-277648-9kxwkcbl	166	2	MPs	mp	NNS
cord-277648-9kxwkcbl	166	3	and	and	CC
cord-277648-9kxwkcbl	166	4	neutrophils	neutrophil	NNS
cord-277648-9kxwkcbl	166	5	appear	appear	VBP
cord-277648-9kxwkcbl	166	6	to	to	TO
cord-277648-9kxwkcbl	166	7	express	express	VB
cord-277648-9kxwkcbl	166	8	the	the	DT
cord-277648-9kxwkcbl	166	9	ligands	ligand	NNS
cord-277648-9kxwkcbl	166	10	of	of	IN
cord-277648-9kxwkcbl	166	11	interest	interest	NN
cord-277648-9kxwkcbl	166	12	(	(	-LRB-
cord-277648-9kxwkcbl	166	13	Figure	figure	NN
cord-277648-9kxwkcbl	166	14	S4B	S4B	NNP
cord-277648-9kxwkcbl	166	15	)	)	-RRB-
cord-277648-9kxwkcbl	166	16	,	,	,
cord-277648-9kxwkcbl	166	17	we	-PRON-	PRP
cord-277648-9kxwkcbl	166	18	investigated	investigate	VBD
cord-277648-9kxwkcbl	166	19	the	the	DT
cord-277648-9kxwkcbl	166	20	role	role	NN
cord-277648-9kxwkcbl	166	21	of	of	IN
cord-277648-9kxwkcbl	166	22	these	these	DT
cord-277648-9kxwkcbl	166	23	cells	cell	NNS
cord-277648-9kxwkcbl	166	24	in	in	IN
cord-277648-9kxwkcbl	166	25	regulating	regulate	VBG
cord-277648-9kxwkcbl	166	26	epithelial	epithelial	JJ
cord-277648-9kxwkcbl	166	27	gene	gene	NN
cord-277648-9kxwkcbl	166	28	expression	expression	NN
cord-277648-9kxwkcbl	166	29	,	,	,
cord-277648-9kxwkcbl	166	30	visualized	visualize	VBN
cord-277648-9kxwkcbl	166	31	in	in	IN
cord-277648-9kxwkcbl	166	32	the	the	DT
cord-277648-9kxwkcbl	166	33	network	network	NN
cord-277648-9kxwkcbl	166	34	diagram	diagram	NN
cord-277648-9kxwkcbl	166	35	in	in	IN
cord-277648-9kxwkcbl	166	36	Figure	Figure	NNP
cord-277648-9kxwkcbl	166	37	4C	4c	CD
cord-277648-9kxwkcbl	166	38	(	(	-LRB-
cord-277648-9kxwkcbl	166	39	at	at	IN
cord-277648-9kxwkcbl	166	40	larger	large	JJR
cord-277648-9kxwkcbl	166	41	scale	scale	NN
cord-277648-9kxwkcbl	166	42	in	in	IN
cord-277648-9kxwkcbl	166	43	Figure	figure	NN
cord-277648-9kxwkcbl	166	44	S4E	s4e	NN
cord-277648-9kxwkcbl	166	45	)	)	-RRB-
cord-277648-9kxwkcbl	166	46	.	.	.
cord-277648-9kxwkcbl	167	1	As	as	IN
cord-277648-9kxwkcbl	167	2	shown	show	VBN
cord-277648-9kxwkcbl	167	3	,	,	,
cord-277648-9kxwkcbl	167	4	MPs	MPs	NNPS
cord-277648-9kxwkcbl	167	5	may	may	MD
cord-277648-9kxwkcbl	167	6	induce	induce	VB
cord-277648-9kxwkcbl	167	7	both	both	DT
cord-277648-9kxwkcbl	167	8	FOS	FOS	NNP
cord-277648-9kxwkcbl	167	9	and	and	CC
cord-277648-9kxwkcbl	167	10	JUN	JUN	NNP
cord-277648-9kxwkcbl	167	11	through	through	IN
cord-277648-9kxwkcbl	167	12	IL1-α	IL1-α	NNP
cord-277648-9kxwkcbl	167	13	,	,	,
cord-277648-9kxwkcbl	167	14	while	while	IN
cord-277648-9kxwkcbl	167	15	neutrophils	neutrophil	NNS
cord-277648-9kxwkcbl	167	16	may	may	MD
cord-277648-9kxwkcbl	167	17	induce	induce	VB
cord-277648-9kxwkcbl	167	18	both	both	DT
cord-277648-9kxwkcbl	167	19	FOS	FOS	NNP
cord-277648-9kxwkcbl	167	20	and	and	CC
cord-277648-9kxwkcbl	167	21	JUN	JUN	NNP
cord-277648-9kxwkcbl	167	22	through	through	IN
cord-277648-9kxwkcbl	167	23	IL1-β	IL1-β	NNPS
cord-277648-9kxwkcbl	167	24	,	,	,
cord-277648-9kxwkcbl	167	25	TNF	TNF	NNP
cord-277648-9kxwkcbl	167	26	,	,	,
cord-277648-9kxwkcbl	167	27	and	and	CC
cord-277648-9kxwkcbl	167	28	IFNG	IFNG	NNP
cord-277648-9kxwkcbl	167	29	,	,	,
cord-277648-9kxwkcbl	167	30	with	with	IN
cord-277648-9kxwkcbl	167	31	additional	additional	JJ
cord-277648-9kxwkcbl	167	32	regulation	regulation	NN
cord-277648-9kxwkcbl	167	33	of	of	IN
cord-277648-9kxwkcbl	167	34	JUN	JUN	NNP
cord-277648-9kxwkcbl	167	35	by	by	IN
cord-277648-9kxwkcbl	167	36	EDN1	EDN1	NNP
cord-277648-9kxwkcbl	167	37	.	.	.
cord-277648-9kxwkcbl	168	1	Finally	finally	RB
cord-277648-9kxwkcbl	168	2	,	,	,
cord-277648-9kxwkcbl	168	3	we	-PRON-	PRP
cord-277648-9kxwkcbl	168	4	aggregated	aggregate	VBD
cord-277648-9kxwkcbl	168	5	ligand	ligand	NN
cord-277648-9kxwkcbl	168	6	-	-	HYPH
cord-277648-9kxwkcbl	168	7	receptor	receptor	NN
cord-277648-9kxwkcbl	168	8	relationships	relationship	NNS
cord-277648-9kxwkcbl	168	9	across	across	IN
cord-277648-9kxwkcbl	168	10	all	all	DT
cord-277648-9kxwkcbl	168	11	of	of	IN
cord-277648-9kxwkcbl	168	12	the	the	DT
cord-277648-9kxwkcbl	168	13	cell	cell	NN
cord-277648-9kxwkcbl	168	14	types	type	NNS
cord-277648-9kxwkcbl	168	15	in	in	IN
cord-277648-9kxwkcbl	168	16	the	the	DT
cord-277648-9kxwkcbl	168	17	BALF	BALF	NNP
cord-277648-9kxwkcbl	168	18	and	and	CC
cord-277648-9kxwkcbl	168	19	proposed	propose	VBD
cord-277648-9kxwkcbl	168	20	broadly	broadly	RB
cord-277648-9kxwkcbl	168	21	-	-	HYPH
cord-277648-9kxwkcbl	168	22	acting	act	VBG
cord-277648-9kxwkcbl	168	23	"	"	''
cord-277648-9kxwkcbl	168	24	pan	pan	NN
cord-277648-9kxwkcbl	168	25	-	-	HYPH
cord-277648-9kxwkcbl	168	26	ligands	ligand	NNS
cord-277648-9kxwkcbl	168	27	"	"	''
cord-277648-9kxwkcbl	168	28	possibly	possibly	RB
cord-277648-9kxwkcbl	168	29	contributing	contribute	VBG
cord-277648-9kxwkcbl	168	30	to	to	IN
cord-277648-9kxwkcbl	168	31	the	the	DT
cord-277648-9kxwkcbl	168	32	induction	induction	NN
cord-277648-9kxwkcbl	168	33	of	of	IN
cord-277648-9kxwkcbl	168	34	transcriptional	transcriptional	JJ
cord-277648-9kxwkcbl	168	35	programs	program	NNS
cord-277648-9kxwkcbl	168	36	in	in	IN
cord-277648-9kxwkcbl	168	37	the	the	DT
cord-277648-9kxwkcbl	168	38	lung	lung	NN
cord-277648-9kxwkcbl	168	39	microenvironment	microenvironment	NN
cord-277648-9kxwkcbl	168	40	.	.	.
cord-277648-9kxwkcbl	169	1	Following	follow	VBG
cord-277648-9kxwkcbl	169	2	the	the	DT
cord-277648-9kxwkcbl	169	3	procedure	procedure	NN
cord-277648-9kxwkcbl	169	4	described	describe	VBN
cord-277648-9kxwkcbl	169	5	above	above	IN
cord-277648-9kxwkcbl	169	6	(	(	-LRB-
cord-277648-9kxwkcbl	169	7	Figure	figure	NN
cord-277648-9kxwkcbl	169	8	4A	4a	CD
cord-277648-9kxwkcbl	169	9	)	)	-RRB-
cord-277648-9kxwkcbl	169	10	using	use	VBG
cord-277648-9kxwkcbl	169	11	each	each	DT
cord-277648-9kxwkcbl	169	12	cell	cell	NN
cord-277648-9kxwkcbl	169	13	type	type	NN
cord-277648-9kxwkcbl	169	14	in	in	IN
cord-277648-9kxwkcbl	169	15	the	the	DT
cord-277648-9kxwkcbl	169	16	BALF	BALF	NNP
cord-277648-9kxwkcbl	169	17	as	as	IN
cord-277648-9kxwkcbl	169	18	a	a	DT
cord-277648-9kxwkcbl	169	19	receiver	receiver	NN
cord-277648-9kxwkcbl	169	20	,	,	,
cord-277648-9kxwkcbl	169	21	we	-PRON-	PRP
cord-277648-9kxwkcbl	169	22	identified	identify	VBD
cord-277648-9kxwkcbl	169	23	a	a	DT
cord-277648-9kxwkcbl	169	24	list	list	NN
cord-277648-9kxwkcbl	169	25	of	of	IN
cord-277648-9kxwkcbl	169	26	potential	potential	JJ
cord-277648-9kxwkcbl	169	27	pan	pan	NN
cord-277648-9kxwkcbl	169	28	-	-	HYPH
cord-277648-9kxwkcbl	169	29	ligands	ligand	NNS
cord-277648-9kxwkcbl	169	30	and	and	CC
cord-277648-9kxwkcbl	169	31	developed	develop	VBD
cord-277648-9kxwkcbl	169	32	a	a	DT
cord-277648-9kxwkcbl	169	33	ligand	ligand	NN
cord-277648-9kxwkcbl	169	34	-	-	HYPH
cord-277648-9kxwkcbl	169	35	receiver	receiver	NN
cord-277648-9kxwkcbl	169	36	cell	cell	NN
cord-277648-9kxwkcbl	169	37	correlation	correlation	NN
cord-277648-9kxwkcbl	169	38	matrix	matrix	NN
cord-277648-9kxwkcbl	169	39	(	(	-LRB-
cord-277648-9kxwkcbl	169	40	Figure	figure	NN
cord-277648-9kxwkcbl	169	41	S4C	s4c	NN
cord-277648-9kxwkcbl	169	42	)	)	-RRB-
cord-277648-9kxwkcbl	169	43	.	.	.
cord-277648-9kxwkcbl	170	1	This	this	DT
cord-277648-9kxwkcbl	170	2	matrix	matrix	NN
cord-277648-9kxwkcbl	170	3	was	be	VBD
cord-277648-9kxwkcbl	170	4	subsequently	subsequently	RB
cord-277648-9kxwkcbl	170	5	filtered	filter	VBN
cord-277648-9kxwkcbl	170	6	to	to	TO
cord-277648-9kxwkcbl	170	7	preserve	preserve	VB
cord-277648-9kxwkcbl	170	8	ligands	ligand	NNS
cord-277648-9kxwkcbl	170	9	acting	act	VBG
cord-277648-9kxwkcbl	170	10	on	on	IN
cord-277648-9kxwkcbl	170	11	over	over	IN
cord-277648-9kxwkcbl	170	12	one	one	CD
cord-277648-9kxwkcbl	170	13	-	-	HYPH
cord-277648-9kxwkcbl	170	14	third	third	NN
cord-277648-9kxwkcbl	170	15	of	of	IN
cord-277648-9kxwkcbl	170	16	cell	cell	NN
cord-277648-9kxwkcbl	170	17	types	type	NNS
cord-277648-9kxwkcbl	170	18	in	in	IN
cord-277648-9kxwkcbl	170	19	the	the	DT
cord-277648-9kxwkcbl	170	20	BALF	BALF	NNP
cord-277648-9kxwkcbl	170	21	(	(	-LRB-
cord-277648-9kxwkcbl	170	22	≥6	≥6	NNP
cord-277648-9kxwkcbl	170	23	cell	cell	NN
cord-277648-9kxwkcbl	170	24	types	type	NNS
cord-277648-9kxwkcbl	170	25	)	)	-RRB-
cord-277648-9kxwkcbl	170	26	with	with	IN
cord-277648-9kxwkcbl	170	27	>	>	XX
cord-277648-9kxwkcbl	170	28	10	10	CD
cord-277648-9kxwkcbl	170	29	%	%	NN
cord-277648-9kxwkcbl	170	30	receptor	receptor	NN
cord-277648-9kxwkcbl	170	31	expression	expression	NN
cord-277648-9kxwkcbl	170	32	and	and	CC
cord-277648-9kxwkcbl	170	33	thresholded	thresholde	VBD
cord-277648-9kxwkcbl	170	34	Pearson	Pearson	NNP
cord-277648-9kxwkcbl	170	35	correlation	correlation	NN
cord-277648-9kxwkcbl	170	36	values	value	NNS
cord-277648-9kxwkcbl	170	37	.	.	.
cord-277648-9kxwkcbl	171	1	Of	of	IN
cord-277648-9kxwkcbl	171	2	these	these	DT
cord-277648-9kxwkcbl	171	3	candidates	candidate	NNS
cord-277648-9kxwkcbl	171	4	,	,	,
cord-277648-9kxwkcbl	171	5	we	-PRON-	PRP
cord-277648-9kxwkcbl	171	6	selected	select	VBD
cord-277648-9kxwkcbl	171	7	ligands	ligand	NNS
cord-277648-9kxwkcbl	171	8	differentially	differentially	RB
cord-277648-9kxwkcbl	171	9	expressed	express	VBN
cord-277648-9kxwkcbl	171	10	between	between	IN
cord-277648-9kxwkcbl	171	11	severe	severe	JJ
cord-277648-9kxwkcbl	171	12	and	and	CC
cord-277648-9kxwkcbl	171	13	moderate	moderate	JJ
cord-277648-9kxwkcbl	171	14	disease	disease	NN
cord-277648-9kxwkcbl	171	15	in	in	IN
cord-277648-9kxwkcbl	171	16	one	one	CD
cord-277648-9kxwkcbl	171	17	or	or	CC
cord-277648-9kxwkcbl	171	18	more	more	JJR
cord-277648-9kxwkcbl	171	19	BALF	BALF	NNP
cord-277648-9kxwkcbl	171	20	cell	cell	NN
cord-277648-9kxwkcbl	171	21	types	type	NNS
cord-277648-9kxwkcbl	171	22	(	(	-LRB-
cord-277648-9kxwkcbl	171	23	Figure	figure	NN
cord-277648-9kxwkcbl	171	24	S4D	s4d	CD
cord-277648-9kxwkcbl	171	25	)	)	-RRB-
cord-277648-9kxwkcbl	171	26	to	to	TO
cord-277648-9kxwkcbl	171	27	further	far	RBR
cord-277648-9kxwkcbl	171	28	filter	filter	VB
cord-277648-9kxwkcbl	171	29	the	the	DT
cord-277648-9kxwkcbl	171	30	ligand	ligand	NN
cord-277648-9kxwkcbl	171	31	-	-	HYPH
cord-277648-9kxwkcbl	171	32	receiver	receiver	NN
cord-277648-9kxwkcbl	171	33	matrix	matrix	NN
cord-277648-9kxwkcbl	171	34	.	.	.
cord-277648-9kxwkcbl	172	1	Interestingly	interestingly	RB
cord-277648-9kxwkcbl	172	2	,	,	,
cord-277648-9kxwkcbl	172	3	the	the	DT
cord-277648-9kxwkcbl	172	4	IL6	IL6	NNP
cord-277648-9kxwkcbl	172	5	transcript	transcript	NN
cord-277648-9kxwkcbl	172	6	was	be	VBD
cord-277648-9kxwkcbl	172	7	not	not	RB
cord-277648-9kxwkcbl	172	8	found	find	VBN
cord-277648-9kxwkcbl	172	9	to	to	TO
cord-277648-9kxwkcbl	172	10	be	be	VB
cord-277648-9kxwkcbl	172	11	differentially	differentially	RB
cord-277648-9kxwkcbl	172	12	expressed	express	VBN
cord-277648-9kxwkcbl	172	13	in	in	IN
cord-277648-9kxwkcbl	172	14	any	any	DT
cord-277648-9kxwkcbl	172	15	of	of	IN
cord-277648-9kxwkcbl	172	16	the	the	DT
cord-277648-9kxwkcbl	172	17	BALF	BALF	NNP
cord-277648-9kxwkcbl	172	18	cell	cell	NN
cord-277648-9kxwkcbl	172	19	types	type	NNS
cord-277648-9kxwkcbl	172	20	and	and	CC
cord-277648-9kxwkcbl	172	21	failed	fail	VBD
cord-277648-9kxwkcbl	172	22	at	at	IN
cord-277648-9kxwkcbl	172	23	this	this	DT
cord-277648-9kxwkcbl	172	24	filtering	filter	VBG
cord-277648-9kxwkcbl	172	25	step	step	NN
cord-277648-9kxwkcbl	172	26	.	.	.
cord-277648-9kxwkcbl	173	1	After	after	IN
cord-277648-9kxwkcbl	173	2	filtering	filter	VBG
cord-277648-9kxwkcbl	173	3	,	,	,
cord-277648-9kxwkcbl	173	4	we	-PRON-	PRP
cord-277648-9kxwkcbl	173	5	arrived	arrive	VBD
cord-277648-9kxwkcbl	173	6	at	at	IN
cord-277648-9kxwkcbl	173	7	a	a	DT
cord-277648-9kxwkcbl	173	8	list	list	NN
cord-277648-9kxwkcbl	173	9	of	of	IN
cord-277648-9kxwkcbl	173	10	differentially	differentially	RB
cord-277648-9kxwkcbl	173	11	expressed	express	VBN
cord-277648-9kxwkcbl	173	12	pan	pan	NN
cord-277648-9kxwkcbl	173	13	-	-	HYPH
cord-277648-9kxwkcbl	173	14	ligands	ligand	NNS
cord-277648-9kxwkcbl	173	15	implicated	implicate	VBN
cord-277648-9kxwkcbl	173	16	in	in	IN
cord-277648-9kxwkcbl	173	17	broad	broad	JJ
cord-277648-9kxwkcbl	173	18	severity	severity	NN
cord-277648-9kxwkcbl	173	19	-	-	HYPH
cord-277648-9kxwkcbl	173	20	specific	specific	JJ
cord-277648-9kxwkcbl	173	21	responses	response	NNS
cord-277648-9kxwkcbl	173	22	across	across	IN
cord-277648-9kxwkcbl	173	23	cell	cell	NN
cord-277648-9kxwkcbl	173	24	types	type	NNS
cord-277648-9kxwkcbl	173	25	in	in	IN
cord-277648-9kxwkcbl	173	26	the	the	DT
cord-277648-9kxwkcbl	173	27	lung	lung	NN
cord-277648-9kxwkcbl	173	28	,	,	,
cord-277648-9kxwkcbl	173	29	consisting	consist	VBG
cord-277648-9kxwkcbl	173	30	of	of	IN
cord-277648-9kxwkcbl	173	31	IFNG	IFNG	NNP
cord-277648-9kxwkcbl	173	32	,	,	,
cord-277648-9kxwkcbl	173	33	IL18	IL18	NNP
cord-277648-9kxwkcbl	173	34	,	,	,
cord-277648-9kxwkcbl	173	35	CCL3	CCL3	NNP
cord-277648-9kxwkcbl	173	36	,	,	,
cord-277648-9kxwkcbl	173	37	CCL8	CCL8	NNP
cord-277648-9kxwkcbl	173	38	,	,	,
cord-277648-9kxwkcbl	173	39	and	and	CC
cord-277648-9kxwkcbl	173	40	SPP1	SPP1	NNS
cord-277648-9kxwkcbl	173	41	.	.	.
cord-277648-9kxwkcbl	174	1	These	these	DT
cord-277648-9kxwkcbl	174	2	ligands	ligand	NNS
cord-277648-9kxwkcbl	174	3	were	be	VBD
cord-277648-9kxwkcbl	174	4	differentially	differentially	RB
cord-277648-9kxwkcbl	174	5	expressed	express	VBN
cord-277648-9kxwkcbl	174	6	in	in	IN
cord-277648-9kxwkcbl	174	7	at	at	RB
cord-277648-9kxwkcbl	174	8	least	least	RBS
cord-277648-9kxwkcbl	174	9	one	one	CD
cord-277648-9kxwkcbl	174	10	BALF	BALF	NNP
cord-277648-9kxwkcbl	174	11	sender	sender	NN
cord-277648-9kxwkcbl	174	12	cell	cell	NN
cord-277648-9kxwkcbl	174	13	type	type	NN
cord-277648-9kxwkcbl	174	14	and	and	CC
cord-277648-9kxwkcbl	174	15	act	act	VB
cord-277648-9kxwkcbl	174	16	on	on	RP
cord-277648-9kxwkcbl	174	17	over	over	IN
cord-277648-9kxwkcbl	174	18	one	one	CD
cord-277648-9kxwkcbl	174	19	-	-	HYPH
cord-277648-9kxwkcbl	174	20	third	third	NN
cord-277648-9kxwkcbl	174	21	of	of	IN
cord-277648-9kxwkcbl	174	22	the	the	DT
cord-277648-9kxwkcbl	174	23	cell	cell	NN
cord-277648-9kxwkcbl	174	24	types	type	NNS
cord-277648-9kxwkcbl	174	25	in	in	IN
cord-277648-9kxwkcbl	174	26	the	the	DT
cord-277648-9kxwkcbl	174	27	BALF	BALF	NNP
cord-277648-9kxwkcbl	174	28	(	(	-LRB-
cord-277648-9kxwkcbl	174	29	Figure	Figure	NNP
cord-277648-9kxwkcbl	174	30	4D	4d	CD
cord-277648-9kxwkcbl	174	31	)	)	-RRB-
cord-277648-9kxwkcbl	174	32	,	,	,
cord-277648-9kxwkcbl	174	33	indicating	indicate	VBG
cord-277648-9kxwkcbl	174	34	these	these	DT
cord-277648-9kxwkcbl	174	35	ligands	ligand	NNS
cord-277648-9kxwkcbl	174	36	should	should	MD
cord-277648-9kxwkcbl	174	37	be	be	VB
cord-277648-9kxwkcbl	174	38	further	further	RB
cord-277648-9kxwkcbl	174	39	investigated	investigate	VBN
cord-277648-9kxwkcbl	174	40	to	to	TO
cord-277648-9kxwkcbl	174	41	elucidate	elucidate	VB
cord-277648-9kxwkcbl	174	42	their	-PRON-	PRP$
cord-277648-9kxwkcbl	174	43	role	role	NN
cord-277648-9kxwkcbl	174	44	in	in	IN
cord-277648-9kxwkcbl	174	45	the	the	DT
cord-277648-9kxwkcbl	174	46	life	life	NN
cord-277648-9kxwkcbl	174	47	-	-	HYPH
cord-277648-9kxwkcbl	174	48	threatening	threaten	VBG
cord-277648-9kxwkcbl	174	49	immunopathology	immunopathology	NN
cord-277648-9kxwkcbl	174	50	of	of	IN
cord-277648-9kxwkcbl	174	51	severe	severe	JJ
cord-277648-9kxwkcbl	174	52	COVID-19	covid-19	NN
cord-277648-9kxwkcbl	174	53	.	.	.
cord-277648-9kxwkcbl	175	1	In	in	IN
cord-277648-9kxwkcbl	175	2	the	the	DT
cord-277648-9kxwkcbl	175	3	course	course	NN
cord-277648-9kxwkcbl	175	4	of	of	IN
cord-277648-9kxwkcbl	175	5	a	a	DT
cord-277648-9kxwkcbl	175	6	severe	severe	JJ
cord-277648-9kxwkcbl	175	7	SARS	SARS	NNP
cord-277648-9kxwkcbl	175	8	-	-	HYPH
cord-277648-9kxwkcbl	175	9	CoV-2	CoV-2	NNP
cord-277648-9kxwkcbl	175	10	viral	viral	JJ
cord-277648-9kxwkcbl	175	11	infection	infection	NN
cord-277648-9kxwkcbl	175	12	,	,	,
cord-277648-9kxwkcbl	175	13	acute	acute	JJ
cord-277648-9kxwkcbl	175	14	pulmonary	pulmonary	JJ
cord-277648-9kxwkcbl	175	15	damage	damage	NN
cord-277648-9kxwkcbl	175	16	has	have	VBZ
cord-277648-9kxwkcbl	175	17	been	be	VBN
cord-277648-9kxwkcbl	175	18	observed	observe	VBN
cord-277648-9kxwkcbl	175	19	concomitantly	concomitantly	RB
cord-277648-9kxwkcbl	175	20	with	with	IN
cord-277648-9kxwkcbl	175	21	elevated	elevated	JJ
cord-277648-9kxwkcbl	175	22	cytokine	cytokine	NN
cord-277648-9kxwkcbl	175	23	levels	level	NNS
cord-277648-9kxwkcbl	175	24	in	in	IN
cord-277648-9kxwkcbl	175	25	serum	serum	NN
cord-277648-9kxwkcbl	175	26	and	and	CC
cord-277648-9kxwkcbl	175	27	infiltration	infiltration	NN
cord-277648-9kxwkcbl	175	28	of	of	IN
cord-277648-9kxwkcbl	175	29	macrophages	macrophage	NNS
cord-277648-9kxwkcbl	175	30	and	and	CC
cord-277648-9kxwkcbl	175	31	lymphocytes	lymphocyte	NNS
cord-277648-9kxwkcbl	175	32	into	into	IN
cord-277648-9kxwkcbl	175	33	multiple	multiple	JJ
cord-277648-9kxwkcbl	175	34	organs	organ	NNS
cord-277648-9kxwkcbl	175	35	,	,	,
cord-277648-9kxwkcbl	175	36	indicative	indicative	JJ
cord-277648-9kxwkcbl	175	37	of	of	IN
cord-277648-9kxwkcbl	175	38	both	both	DT
cord-277648-9kxwkcbl	175	39	local	local	JJ
cord-277648-9kxwkcbl	175	40	and	and	CC
cord-277648-9kxwkcbl	175	41	systemic	systemic	JJ
cord-277648-9kxwkcbl	175	42	immunological	immunological	JJ
cord-277648-9kxwkcbl	175	43	responses	response	NNS
cord-277648-9kxwkcbl	175	44	[	[	-LRB-
cord-277648-9kxwkcbl	175	45	11	11	CD
cord-277648-9kxwkcbl	175	46	,	,	,
cord-277648-9kxwkcbl	175	47	15	15	CD
cord-277648-9kxwkcbl	175	48	]	]	-RRB-
cord-277648-9kxwkcbl	175	49	.	.	.
cord-277648-9kxwkcbl	176	1	To	to	TO
cord-277648-9kxwkcbl	176	2	better	well	RBR
cord-277648-9kxwkcbl	176	3	understand	understand	VB
cord-277648-9kxwkcbl	176	4	these	these	DT
cord-277648-9kxwkcbl	176	5	dynamics	dynamic	NNS
cord-277648-9kxwkcbl	176	6	,	,	,
cord-277648-9kxwkcbl	176	7	we	-PRON-	PRP
cord-277648-9kxwkcbl	176	8	leveraged	leverage	VBD
cord-277648-9kxwkcbl	176	9	scRNA	scrna	XX
cord-277648-9kxwkcbl	176	10	-	-	HYPH
cord-277648-9kxwkcbl	176	11	seq	seq	NN
cord-277648-9kxwkcbl	176	12	data	datum	NNS
cord-277648-9kxwkcbl	176	13	from	from	IN
cord-277648-9kxwkcbl	176	14	BALF	BALF	NNP
cord-277648-9kxwkcbl	176	15	and	and	CC
cord-277648-9kxwkcbl	176	16	blood	blood	NN
cord-277648-9kxwkcbl	176	17	to	to	TO
cord-277648-9kxwkcbl	176	18	compare	compare	VB
cord-277648-9kxwkcbl	176	19	severity	severity	NN
cord-277648-9kxwkcbl	176	20	-	-	HYPH
cord-277648-9kxwkcbl	176	21	specific	specific	JJ
cord-277648-9kxwkcbl	176	22	shifts	shift	NNS
cord-277648-9kxwkcbl	176	23	in	in	IN
cord-277648-9kxwkcbl	176	24	cellular	cellular	JJ
cord-277648-9kxwkcbl	176	25	composition	composition	NN
cord-277648-9kxwkcbl	176	26	at	at	IN
cord-277648-9kxwkcbl	176	27	the	the	DT
cord-277648-9kxwkcbl	176	28	local	local	JJ
cord-277648-9kxwkcbl	176	29	and	and	CC
cord-277648-9kxwkcbl	176	30	systemic	systemic	JJ
cord-277648-9kxwkcbl	176	31	levels	level	NNS
cord-277648-9kxwkcbl	176	32	.	.	.
cord-277648-9kxwkcbl	177	1	In	in	IN
cord-277648-9kxwkcbl	177	2	BALF	BALF	NNP
cord-277648-9kxwkcbl	177	3	,	,	,
cord-277648-9kxwkcbl	177	4	compositional	compositional	JJ
cord-277648-9kxwkcbl	177	5	analysis	analysis	NN
cord-277648-9kxwkcbl	177	6	indicated	indicate	VBD
cord-277648-9kxwkcbl	177	7	expansion	expansion	NN
cord-277648-9kxwkcbl	177	8	of	of	IN
cord-277648-9kxwkcbl	177	9	NK	NK	NNP
cord-277648-9kxwkcbl	177	10	cells	cell	NNS
cord-277648-9kxwkcbl	177	11	,	,	,
cord-277648-9kxwkcbl	177	12	T	t	NN
cord-277648-9kxwkcbl	177	13	cells	cell	NNS
cord-277648-9kxwkcbl	177	14	(	(	-LRB-
cord-277648-9kxwkcbl	177	15	general	general	JJ
cord-277648-9kxwkcbl	177	16	T	T	NNP
cord-277648-9kxwkcbl	177	17	cell	cell	NN
cord-277648-9kxwkcbl	177	18	population	population	NN
cord-277648-9kxwkcbl	177	19	,	,	,
cord-277648-9kxwkcbl	177	20	CD4	CD4	NNP
cord-277648-9kxwkcbl	177	21	+	+	CC
cord-277648-9kxwkcbl	177	22	naive	naive	JJ
cord-277648-9kxwkcbl	177	23	T	t	NN
cord-277648-9kxwkcbl	177	24	cells	cell	NNS
cord-277648-9kxwkcbl	177	25	,	,	,
cord-277648-9kxwkcbl	177	26	and	and	CC
cord-277648-9kxwkcbl	177	27	CD4	CD4	NNP
cord-277648-9kxwkcbl	177	28	+	+	CC
cord-277648-9kxwkcbl	177	29	effector	effector	VB
cord-277648-9kxwkcbl	177	30	Treg	Treg	NNP
cord-277648-9kxwkcbl	177	31	cells	cell	NNS
cord-277648-9kxwkcbl	177	32	)	)	-RRB-
cord-277648-9kxwkcbl	177	33	,	,	,
cord-277648-9kxwkcbl	177	34	and	and	CC
cord-277648-9kxwkcbl	177	35	pDCs	pdc	VBD
cord-277648-9kxwkcbl	177	36	in	in	IN
cord-277648-9kxwkcbl	177	37	moderate	moderate	JJ
cord-277648-9kxwkcbl	177	38	patients	patient	NNS
cord-277648-9kxwkcbl	177	39	compared	compare	VBN
cord-277648-9kxwkcbl	177	40	to	to	IN
cord-277648-9kxwkcbl	177	41	both	both	CC
cord-277648-9kxwkcbl	177	42	severe	severe	JJ
cord-277648-9kxwkcbl	177	43	and	and	CC
cord-277648-9kxwkcbl	177	44	control	control	NN
cord-277648-9kxwkcbl	177	45	patients	patient	NNS
cord-277648-9kxwkcbl	177	46	.	.	.
cord-277648-9kxwkcbl	178	1	Although	although	IN
cord-277648-9kxwkcbl	178	2	severityspecific	severityspecific	JJ
cord-277648-9kxwkcbl	178	3	compositional	compositional	JJ
cord-277648-9kxwkcbl	178	4	changes	change	NNS
cord-277648-9kxwkcbl	178	5	in	in	IN
cord-277648-9kxwkcbl	178	6	BALF	BALF	NNP
cord-277648-9kxwkcbl	178	7	samples	sample	NNS
cord-277648-9kxwkcbl	178	8	remain	remain	VBP
cord-277648-9kxwkcbl	178	9	largely	largely	RB
cord-277648-9kxwkcbl	178	10	unaddressed	unaddressed	JJ
cord-277648-9kxwkcbl	178	11	in	in	IN
cord-277648-9kxwkcbl	178	12	the	the	DT
cord-277648-9kxwkcbl	178	13	literature	literature	NN
cord-277648-9kxwkcbl	178	14	[	[	-LRB-
cord-277648-9kxwkcbl	178	15	27	27	CD
cord-277648-9kxwkcbl	178	16	]	]	-RRB-
cord-277648-9kxwkcbl	178	17	,	,	,
cord-277648-9kxwkcbl	178	18	the	the	DT
cord-277648-9kxwkcbl	178	19	severity	severity	NN
cord-277648-9kxwkcbl	178	20	-	-	HYPH
cord-277648-9kxwkcbl	178	21	specific	specific	JJ
cord-277648-9kxwkcbl	178	22	lymphopenia	lymphopenia	NN
cord-277648-9kxwkcbl	178	23	of	of	IN
cord-277648-9kxwkcbl	178	24	NK	NK	NNP
cord-277648-9kxwkcbl	178	25	cells	cell	NNS
cord-277648-9kxwkcbl	178	26	and	and	CC
cord-277648-9kxwkcbl	178	27	CD4	CD4	NNP
cord-277648-9kxwkcbl	178	28	+	+	CC
cord-277648-9kxwkcbl	178	29	naive	naive	JJ
cord-277648-9kxwkcbl	178	30	T	t	NN
cord-277648-9kxwkcbl	178	31	cells	cell	NNS
cord-277648-9kxwkcbl	178	32	that	that	WDT
cord-277648-9kxwkcbl	178	33	we	-PRON-	PRP
cord-277648-9kxwkcbl	178	34	report	report	VBP
cord-277648-9kxwkcbl	178	35	in	in	IN
cord-277648-9kxwkcbl	178	36	BALF	BALF	NNP
cord-277648-9kxwkcbl	178	37	agrees	agree	VBZ
cord-277648-9kxwkcbl	178	38	with	with	IN
cord-277648-9kxwkcbl	178	39	findings	finding	NNS
cord-277648-9kxwkcbl	178	40	from	from	IN
cord-277648-9kxwkcbl	178	41	compositional	compositional	JJ
cord-277648-9kxwkcbl	178	42	studies	study	NNS
cord-277648-9kxwkcbl	178	43	of	of	IN
cord-277648-9kxwkcbl	178	44	PBMCs	pbmc	NNS
cord-277648-9kxwkcbl	178	45	[	[	-LRB-
cord-277648-9kxwkcbl	178	46	30	30	CD
cord-277648-9kxwkcbl	178	47	,	,	,
cord-277648-9kxwkcbl	178	48	31	31	CD
cord-277648-9kxwkcbl	178	49	,	,	,
cord-277648-9kxwkcbl	178	50	34	34	CD
cord-277648-9kxwkcbl	178	51	]	]	-RRB-
cord-277648-9kxwkcbl	178	52	.	.	.
cord-277648-9kxwkcbl	179	1	We	-PRON-	PRP
cord-277648-9kxwkcbl	179	2	additionally	additionally	RB
cord-277648-9kxwkcbl	179	3	report	report	VBP
cord-277648-9kxwkcbl	179	4	severity	severity	NN
cord-277648-9kxwkcbl	179	5	-	-	HYPH
cord-277648-9kxwkcbl	179	6	specific	specific	JJ
cord-277648-9kxwkcbl	179	7	compositional	compositional	JJ
cord-277648-9kxwkcbl	179	8	shifts	shift	NNS
cord-277648-9kxwkcbl	179	9	in	in	IN
cord-277648-9kxwkcbl	179	10	lung	lung	NN
cord-277648-9kxwkcbl	179	11	MP	MP	NNP
cord-277648-9kxwkcbl	179	12	populations	population	NNS
cord-277648-9kxwkcbl	179	13	and	and	CC
cord-277648-9kxwkcbl	179	14	identify	identify	VB
cord-277648-9kxwkcbl	179	15	clusters	cluster	NNS
cord-277648-9kxwkcbl	179	16	expressing	express	VBG
cord-277648-9kxwkcbl	179	17	MRC1	MRC1	NNP
cord-277648-9kxwkcbl	179	18	,	,	,
cord-277648-9kxwkcbl	179	19	C1QA	c1qa	UH
cord-277648-9kxwkcbl	179	20	,	,	,
cord-277648-9kxwkcbl	179	21	and	and	CC
cord-277648-9kxwkcbl	179	22	FABP4	FABP4	NNP
cord-277648-9kxwkcbl	179	23	suggesting	suggest	VBG
cord-277648-9kxwkcbl	179	24	an	an	DT
cord-277648-9kxwkcbl	179	25	M2	M2	NNP
cord-277648-9kxwkcbl	179	26	macrophage	macrophage	NN
cord-277648-9kxwkcbl	179	27	-	-	HYPH
cord-277648-9kxwkcbl	179	28	like	like	JJ
cord-277648-9kxwkcbl	179	29	phenotype	phenotype	NN
cord-277648-9kxwkcbl	179	30	expanded	expand	VBN
cord-277648-9kxwkcbl	179	31	in	in	IN
cord-277648-9kxwkcbl	179	32	control	control	NN
cord-277648-9kxwkcbl	179	33	subjects	subject	NNS
cord-277648-9kxwkcbl	179	34	.	.	.
cord-277648-9kxwkcbl	180	1	Moderate	moderate	JJ
cord-277648-9kxwkcbl	180	2	donors	donor	NNS
cord-277648-9kxwkcbl	180	3	showed	show	VBD
cord-277648-9kxwkcbl	180	4	expanded	expand	VBN
cord-277648-9kxwkcbl	180	5	clusters	cluster	NNS
cord-277648-9kxwkcbl	180	6	expressing	express	VBG
cord-277648-9kxwkcbl	180	7	HLADQA1	HLADQA1	NNP
cord-277648-9kxwkcbl	180	8	and	and	CC
cord-277648-9kxwkcbl	180	9	HLADQA2	HLADQA2	NNP
cord-277648-9kxwkcbl	180	10	,	,	,
cord-277648-9kxwkcbl	180	11	indicating	indicate	VBG
cord-277648-9kxwkcbl	180	12	increased	increase	VBN
cord-277648-9kxwkcbl	180	13	antigen	antigen	NN
cord-277648-9kxwkcbl	180	14	presentation	presentation	NN
cord-277648-9kxwkcbl	180	15	through	through	IN
cord-277648-9kxwkcbl	180	16	HLA	HLA	NNP
cord-277648-9kxwkcbl	180	17	class	class	NN
cord-277648-9kxwkcbl	180	18	II	II	NNP
cord-277648-9kxwkcbl	180	19	.	.	.
cord-277648-9kxwkcbl	181	1	Expanded	expand	VBN
cord-277648-9kxwkcbl	181	2	clusters	cluster	NNS
cord-277648-9kxwkcbl	181	3	in	in	IN
cord-277648-9kxwkcbl	181	4	severe	severe	JJ
cord-277648-9kxwkcbl	181	5	donors	donor	NNS
cord-277648-9kxwkcbl	181	6	expressing	express	VBG
cord-277648-9kxwkcbl	181	7	SPP1	SPP1	NNS
cord-277648-9kxwkcbl	181	8	as	as	RB
cord-277648-9kxwkcbl	181	9	well	well	RB
cord-277648-9kxwkcbl	181	10	as	as	IN
cord-277648-9kxwkcbl	181	11	various	various	JJ
cord-277648-9kxwkcbl	181	12	chemokines	chemokine	NNS
cord-277648-9kxwkcbl	181	13	including	include	VBG
cord-277648-9kxwkcbl	181	14	CCL2	CCL2	NNP
cord-277648-9kxwkcbl	181	15	,	,	,
cord-277648-9kxwkcbl	181	16	CCL3	CCL3	NNP
cord-277648-9kxwkcbl	181	17	,	,	,
cord-277648-9kxwkcbl	181	18	and	and	CC
cord-277648-9kxwkcbl	181	19	CCL8	CCL8	NNP
cord-277648-9kxwkcbl	181	20	are	be	VBP
cord-277648-9kxwkcbl	181	21	likely	likely	RB
cord-277648-9kxwkcbl	181	22	associated	associate	VBN
cord-277648-9kxwkcbl	181	23	with	with	IN
cord-277648-9kxwkcbl	181	24	an	an	DT
cord-277648-9kxwkcbl	181	25	M1	M1	NNP
cord-277648-9kxwkcbl	181	26	macrophage	macrophage	NN
cord-277648-9kxwkcbl	181	27	-	-	HYPH
cord-277648-9kxwkcbl	181	28	like	like	JJ
cord-277648-9kxwkcbl	181	29	phenotype	phenotype	NN
cord-277648-9kxwkcbl	181	30	,	,	,
cord-277648-9kxwkcbl	181	31	in	in	IN
cord-277648-9kxwkcbl	181	32	agreement	agreement	NN
cord-277648-9kxwkcbl	181	33	with	with	IN
cord-277648-9kxwkcbl	181	34	previous	previous	JJ
cord-277648-9kxwkcbl	181	35	analyses	analysis	NNS
cord-277648-9kxwkcbl	181	36	[	[	-LRB-
cord-277648-9kxwkcbl	181	37	27	27	CD
cord-277648-9kxwkcbl	181	38	]	]	-RRB-
cord-277648-9kxwkcbl	181	39	.	.	.
cord-277648-9kxwkcbl	182	1	Strong	strong	JJ
cord-277648-9kxwkcbl	182	2	macrophage	macrophage	NN
cord-277648-9kxwkcbl	182	3	expression	expression	NN
cord-277648-9kxwkcbl	182	4	of	of	IN
cord-277648-9kxwkcbl	182	5	osteopontin	osteopontin	NNP
cord-277648-9kxwkcbl	182	6	,	,	,
cord-277648-9kxwkcbl	182	7	the	the	DT
cord-277648-9kxwkcbl	182	8	gene	gene	NN
cord-277648-9kxwkcbl	182	9	product	product	NN
cord-277648-9kxwkcbl	182	10	of	of	IN
cord-277648-9kxwkcbl	182	11	SPP1	SPP1	NNP
cord-277648-9kxwkcbl	182	12	,	,	,
cord-277648-9kxwkcbl	182	13	has	have	VBZ
cord-277648-9kxwkcbl	182	14	been	be	VBN
cord-277648-9kxwkcbl	182	15	previously	previously	RB
cord-277648-9kxwkcbl	182	16	observed	observe	VBN
cord-277648-9kxwkcbl	182	17	during	during	IN
cord-277648-9kxwkcbl	182	18	influenza	influenza	NN
cord-277648-9kxwkcbl	182	19	A	a	DT
cord-277648-9kxwkcbl	182	20	infection	infection	NN
cord-277648-9kxwkcbl	182	21	,	,	,
cord-277648-9kxwkcbl	182	22	suggesting	suggest	VBG
cord-277648-9kxwkcbl	182	23	that	that	IN
cord-277648-9kxwkcbl	182	24	macrophages	macrophage	NNS
cord-277648-9kxwkcbl	182	25	in	in	IN
cord-277648-9kxwkcbl	182	26	severe	severe	JJ
cord-277648-9kxwkcbl	182	27	COVID-19	COVID-19	NNP
cord-277648-9kxwkcbl	182	28	may	may	MD
cord-277648-9kxwkcbl	182	29	be	be	VB
cord-277648-9kxwkcbl	182	30	following	follow	VBG
cord-277648-9kxwkcbl	182	31	a	a	DT
cord-277648-9kxwkcbl	182	32	similar	similar	JJ
cord-277648-9kxwkcbl	182	33	viral	viral	JJ
cord-277648-9kxwkcbl	182	34	response	response	NN
cord-277648-9kxwkcbl	182	35	to	to	IN
cord-277648-9kxwkcbl	182	36	influenza	influenza	NN
cord-277648-9kxwkcbl	182	37	[	[	-LRB-
cord-277648-9kxwkcbl	182	38	43	43	CD
cord-277648-9kxwkcbl	182	39	]	]	-RRB-
cord-277648-9kxwkcbl	182	40	.	.	.
cord-277648-9kxwkcbl	183	1	Compositional	compositional	JJ
cord-277648-9kxwkcbl	183	2	changes	change	NNS
cord-277648-9kxwkcbl	183	3	were	be	VBD
cord-277648-9kxwkcbl	183	4	not	not	RB
cord-277648-9kxwkcbl	183	5	readily	readily	RB
cord-277648-9kxwkcbl	183	6	apparent	apparent	JJ
cord-277648-9kxwkcbl	183	7	in	in	IN
cord-277648-9kxwkcbl	183	8	PBMCs	pbmc	NNS
cord-277648-9kxwkcbl	183	9	when	when	WRB
cord-277648-9kxwkcbl	183	10	comparing	compare	VBG
cord-277648-9kxwkcbl	183	11	ARDS	ARDS	NNP
cord-277648-9kxwkcbl	183	12	patients	patient	NNS
cord-277648-9kxwkcbl	183	13	to	to	IN
cord-277648-9kxwkcbl	183	14	non	non	JJ
cord-277648-9kxwkcbl	183	15	-	-	JJ
cord-277648-9kxwkcbl	183	16	ARDS	ARDS	NNP
cord-277648-9kxwkcbl	183	17	patients	patient	NNS
cord-277648-9kxwkcbl	183	18	,	,	,
cord-277648-9kxwkcbl	183	19	although	although	IN
cord-277648-9kxwkcbl	183	20	we	-PRON-	PRP
cord-277648-9kxwkcbl	183	21	observed	observe	VBD
cord-277648-9kxwkcbl	183	22	an	an	DT
cord-277648-9kxwkcbl	183	23	expansion	expansion	NN
cord-277648-9kxwkcbl	183	24	of	of	IN
cord-277648-9kxwkcbl	183	25	multiple	multiple	JJ
cord-277648-9kxwkcbl	183	26	plasma	plasma	NN
cord-277648-9kxwkcbl	183	27	cell	cell	NN
cord-277648-9kxwkcbl	183	28	types	type	NNS
cord-277648-9kxwkcbl	183	29	in	in	IN
cord-277648-9kxwkcbl	183	30	ARDS	ARDS	NNP
cord-277648-9kxwkcbl	183	31	patients	patient	NNS
cord-277648-9kxwkcbl	183	32	compared	compare	VBN
cord-277648-9kxwkcbl	183	33	to	to	IN
cord-277648-9kxwkcbl	183	34	healthy	healthy	JJ
cord-277648-9kxwkcbl	183	35	control	control	NN
cord-277648-9kxwkcbl	183	36	subjects	subject	NNS
cord-277648-9kxwkcbl	183	37	,	,	,
cord-277648-9kxwkcbl	183	38	consistent	consistent	JJ
cord-277648-9kxwkcbl	183	39	with	with	IN
cord-277648-9kxwkcbl	183	40	previous	previous	JJ
cord-277648-9kxwkcbl	183	41	reports	report	NNS
cord-277648-9kxwkcbl	183	42	[	[	-LRB-
cord-277648-9kxwkcbl	183	43	23	23	CD
cord-277648-9kxwkcbl	183	44	,	,	,
cord-277648-9kxwkcbl	183	45	33	33	CD
cord-277648-9kxwkcbl	183	46	,	,	,
cord-277648-9kxwkcbl	183	47	34	34	CD
cord-277648-9kxwkcbl	183	48	,	,	,
cord-277648-9kxwkcbl	183	49	44	44	CD
cord-277648-9kxwkcbl	183	50	]	]	-RRB-
cord-277648-9kxwkcbl	183	51	.	.	.
cord-277648-9kxwkcbl	184	1	Despite	despite	IN
cord-277648-9kxwkcbl	184	2	recent	recent	JJ
cord-277648-9kxwkcbl	184	3	advances	advance	NNS
cord-277648-9kxwkcbl	184	4	,	,	,
cord-277648-9kxwkcbl	184	5	the	the	DT
cord-277648-9kxwkcbl	184	6	immunological	immunological	JJ
cord-277648-9kxwkcbl	184	7	signatures	signature	NNS
cord-277648-9kxwkcbl	184	8	of	of	IN
cord-277648-9kxwkcbl	184	9	severe	severe	JJ
cord-277648-9kxwkcbl	184	10	COVID-19	covid-19	NN
cord-277648-9kxwkcbl	184	11	remain	remain	VBP
cord-277648-9kxwkcbl	184	12	largely	largely	RB
cord-277648-9kxwkcbl	184	13	uncharacterized	uncharacterized	JJ
cord-277648-9kxwkcbl	184	14	in	in	IN
cord-277648-9kxwkcbl	184	15	both	both	CC
cord-277648-9kxwkcbl	184	16	the	the	DT
cord-277648-9kxwkcbl	184	17	lung	lung	NN
cord-277648-9kxwkcbl	184	18	[	[	-LRB-
cord-277648-9kxwkcbl	184	19	27	27	CD
cord-277648-9kxwkcbl	184	20	,	,	,
cord-277648-9kxwkcbl	184	21	28	28	CD
cord-277648-9kxwkcbl	184	22	]	]	-RRB-
cord-277648-9kxwkcbl	184	23	and	and	CC
cord-277648-9kxwkcbl	184	24	systemic	systemic	JJ
cord-277648-9kxwkcbl	184	25	circulation	circulation	NN
cord-277648-9kxwkcbl	184	26	[	[	-LRB-
cord-277648-9kxwkcbl	184	27	34	34	CD
cord-277648-9kxwkcbl	184	28	,	,	,
cord-277648-9kxwkcbl	184	29	36	36	CD
cord-277648-9kxwkcbl	184	30	]	]	-RRB-
cord-277648-9kxwkcbl	184	31	.	.	.
cord-277648-9kxwkcbl	185	1	In	in	IN
cord-277648-9kxwkcbl	185	2	particular	particular	JJ
cord-277648-9kxwkcbl	185	3	,	,	,
cord-277648-9kxwkcbl	185	4	a	a	DT
cord-277648-9kxwkcbl	185	5	need	need	NN
cord-277648-9kxwkcbl	185	6	exists	exist	VBZ
cord-277648-9kxwkcbl	185	7	to	to	TO
cord-277648-9kxwkcbl	185	8	define	define	VB
cord-277648-9kxwkcbl	185	9	markers	marker	NNS
cord-277648-9kxwkcbl	185	10	of	of	IN
cord-277648-9kxwkcbl	185	11	severity	severity	NN
cord-277648-9kxwkcbl	185	12	that	that	WDT
cord-277648-9kxwkcbl	185	13	can	can	MD
cord-277648-9kxwkcbl	185	14	be	be	VB
cord-277648-9kxwkcbl	185	15	used	use	VBN
cord-277648-9kxwkcbl	185	16	to	to	TO
cord-277648-9kxwkcbl	185	17	assess	assess	VB
cord-277648-9kxwkcbl	185	18	patient	patient	JJ
cord-277648-9kxwkcbl	185	19	disease	disease	NN
cord-277648-9kxwkcbl	185	20	trajectory	trajectory	NN
cord-277648-9kxwkcbl	185	21	in	in	IN
cord-277648-9kxwkcbl	185	22	a	a	DT
cord-277648-9kxwkcbl	185	23	clinical	clinical	JJ
cord-277648-9kxwkcbl	185	24	setting	setting	NN
cord-277648-9kxwkcbl	185	25	for	for	IN
cord-277648-9kxwkcbl	185	26	the	the	DT
cord-277648-9kxwkcbl	185	27	purposes	purpose	NNS
cord-277648-9kxwkcbl	185	28	of	of	IN
cord-277648-9kxwkcbl	185	29	triage	triage	NN
cord-277648-9kxwkcbl	185	30	or	or	CC
cord-277648-9kxwkcbl	185	31	to	to	TO
cord-277648-9kxwkcbl	185	32	inform	inform	VB
cord-277648-9kxwkcbl	185	33	the	the	DT
cord-277648-9kxwkcbl	185	34	use	use	NN
cord-277648-9kxwkcbl	185	35	of	of	IN
cord-277648-9kxwkcbl	185	36	immunomodulatory	immunomodulatory	JJ
cord-277648-9kxwkcbl	185	37	treatment	treatment	NN
cord-277648-9kxwkcbl	185	38	strategies	strategy	NNS
cord-277648-9kxwkcbl	185	39	[	[	-LRB-
cord-277648-9kxwkcbl	185	40	34	34	CD
cord-277648-9kxwkcbl	185	41	]	]	-RRB-
cord-277648-9kxwkcbl	185	42	.	.	.
cord-277648-9kxwkcbl	186	1	Here	here	RB
cord-277648-9kxwkcbl	186	2	,	,	,
cord-277648-9kxwkcbl	186	3	we	-PRON-	PRP
cord-277648-9kxwkcbl	186	4	leveraged	leverage	VBD
cord-277648-9kxwkcbl	186	5	BALF	BALF	NNP
cord-277648-9kxwkcbl	186	6	and	and	CC
cord-277648-9kxwkcbl	186	7	PBMC	PBMC	NNP
cord-277648-9kxwkcbl	186	8	transcriptional	transcriptional	JJ
cord-277648-9kxwkcbl	186	9	data	datum	NNS
cord-277648-9kxwkcbl	186	10	to	to	TO
cord-277648-9kxwkcbl	186	11	nominate	nominate	VB
cord-277648-9kxwkcbl	186	12	cell	cell	NN
cord-277648-9kxwkcbl	186	13	surface	surface	NN
cord-277648-9kxwkcbl	186	14	proteins	protein	NNS
cord-277648-9kxwkcbl	186	15	that	that	WDT
cord-277648-9kxwkcbl	186	16	could	could	MD
cord-277648-9kxwkcbl	186	17	be	be	VB
cord-277648-9kxwkcbl	186	18	incorporated	incorporate	VBN
cord-277648-9kxwkcbl	186	19	into	into	IN
cord-277648-9kxwkcbl	186	20	a	a	DT
cord-277648-9kxwkcbl	186	21	flow	flow	NN
cord-277648-9kxwkcbl	186	22	cytometry	cytometry	NN
cord-277648-9kxwkcbl	186	23	panel	panel	NN
cord-277648-9kxwkcbl	186	24	for	for	IN
cord-277648-9kxwkcbl	186	25	COVID-19	COVID-19	NNP
cord-277648-9kxwkcbl	186	26	patient	patient	JJ
cord-277648-9kxwkcbl	186	27	immunophenotyping	immunophenotyping	NN
cord-277648-9kxwkcbl	186	28	.	.	.
cord-277648-9kxwkcbl	187	1	Notably	notably	RB
cord-277648-9kxwkcbl	187	2	,	,	,
cord-277648-9kxwkcbl	187	3	in	in	IN
cord-277648-9kxwkcbl	187	4	BALF	BALF	NNP
cord-277648-9kxwkcbl	187	5	samples	sample	NNS
cord-277648-9kxwkcbl	187	6	we	-PRON-	PRP
cord-277648-9kxwkcbl	187	7	observed	observe	VBD
cord-277648-9kxwkcbl	187	8	upregulation	upregulation	NN
cord-277648-9kxwkcbl	187	9	of	of	IN
cord-277648-9kxwkcbl	187	10	AREG	AREG	NNP
cord-277648-9kxwkcbl	187	11	in	in	IN
cord-277648-9kxwkcbl	187	12	pDCs	pDCs	NNP
cord-277648-9kxwkcbl	188	1	and	and	CC
cord-277648-9kxwkcbl	188	2	mDCs	mdcs	NN
cord-277648-9kxwkcbl	188	3	of	of	IN
cord-277648-9kxwkcbl	188	4	patients	patient	NNS
cord-277648-9kxwkcbl	188	5	undergoing	undergo	VBG
cord-277648-9kxwkcbl	188	6	a	a	DT
cord-277648-9kxwkcbl	188	7	severe	severe	JJ
cord-277648-9kxwkcbl	188	8	disease	disease	NN
cord-277648-9kxwkcbl	188	9	course	course	NN
cord-277648-9kxwkcbl	188	10	compared	compare	VBN
cord-277648-9kxwkcbl	188	11	to	to	IN
cord-277648-9kxwkcbl	188	12	patients	patient	NNS
cord-277648-9kxwkcbl	188	13	who	who	WP
cord-277648-9kxwkcbl	188	14	experienced	experience	VBD
cord-277648-9kxwkcbl	188	15	moderate	moderate	JJ
cord-277648-9kxwkcbl	188	16	disease	disease	NN
cord-277648-9kxwkcbl	188	17	.	.	.
cord-277648-9kxwkcbl	189	1	The	the	DT
cord-277648-9kxwkcbl	189	2	AREG	AREG	NNP
cord-277648-9kxwkcbl	189	3	transcript	transcript	NN
cord-277648-9kxwkcbl	189	4	was	be	VBD
cord-277648-9kxwkcbl	189	5	verified	verify	VBN
cord-277648-9kxwkcbl	189	6	to	to	TO
cord-277648-9kxwkcbl	189	7	be	be	VB
cord-277648-9kxwkcbl	189	8	expressed	express	VBN
cord-277648-9kxwkcbl	189	9	by	by	IN
cord-277648-9kxwkcbl	189	10	dendritic	dendritic	JJ
cord-277648-9kxwkcbl	189	11	cells	cell	NNS
cord-277648-9kxwkcbl	189	12	in	in	IN
cord-277648-9kxwkcbl	189	13	bulk	bulk	JJ
cord-277648-9kxwkcbl	189	14	RNA	RNA	NNP
cord-277648-9kxwkcbl	189	15	-	-	HYPH
cord-277648-9kxwkcbl	189	16	seq	seq	NNP
cord-277648-9kxwkcbl	189	17	data	datum	NNS
cord-277648-9kxwkcbl	189	18	[	[	-LRB-
cord-277648-9kxwkcbl	189	19	39	39	CD
cord-277648-9kxwkcbl	189	20	,	,	,
cord-277648-9kxwkcbl	189	21	40	40	CD
cord-277648-9kxwkcbl	189	22	]	]	-RRB-
cord-277648-9kxwkcbl	189	23	,	,	,
cord-277648-9kxwkcbl	189	24	has	have	VBZ
cord-277648-9kxwkcbl	189	25	been	be	VBN
cord-277648-9kxwkcbl	189	26	previously	previously	RB
cord-277648-9kxwkcbl	189	27	shown	show	VBN
cord-277648-9kxwkcbl	189	28	to	to	TO
cord-277648-9kxwkcbl	189	29	orchestrate	orchestrate	VB
cord-277648-9kxwkcbl	189	30	tissue	tissue	NN
cord-277648-9kxwkcbl	189	31	homeostasis	homeostasis	NN
cord-277648-9kxwkcbl	189	32	during	during	IN
cord-277648-9kxwkcbl	189	33	influenza	influenza	NN
cord-277648-9kxwkcbl	189	34	infection	infection	NN
cord-277648-9kxwkcbl	189	35	[	[	-LRB-
cord-277648-9kxwkcbl	189	36	45	45	CD
cord-277648-9kxwkcbl	189	37	,	,	,
cord-277648-9kxwkcbl	189	38	46	46	CD
cord-277648-9kxwkcbl	189	39	]	]	-RRB-
cord-277648-9kxwkcbl	189	40	,	,	,
cord-277648-9kxwkcbl	189	41	and	and	CC
cord-277648-9kxwkcbl	189	42	has	have	VBZ
cord-277648-9kxwkcbl	189	43	been	be	VBN
cord-277648-9kxwkcbl	189	44	previously	previously	RB
cord-277648-9kxwkcbl	189	45	labeled	label	VBN
cord-277648-9kxwkcbl	189	46	in	in	IN
cord-277648-9kxwkcbl	189	47	flow	flow	NN
cord-277648-9kxwkcbl	189	48	cytometry	cytometry	NN
cord-277648-9kxwkcbl	189	49	studies	study	NNS
cord-277648-9kxwkcbl	189	50	[	[	-LRB-
cord-277648-9kxwkcbl	189	51	47	47	CD
cord-277648-9kxwkcbl	189	52	]	]	-RRB-
cord-277648-9kxwkcbl	189	53	.	.	.
cord-277648-9kxwkcbl	190	1	Additionally	additionally	RB
cord-277648-9kxwkcbl	190	2	,	,	,
cord-277648-9kxwkcbl	190	3	TIMP1	TIMP1	NNP
cord-277648-9kxwkcbl	190	4	,	,	,
cord-277648-9kxwkcbl	190	5	VAMP5	VAMP5	NNP
cord-277648-9kxwkcbl	190	6	,	,	,
cord-277648-9kxwkcbl	190	7	and	and	CC
cord-277648-9kxwkcbl	190	8	IL1R2	IL1R2	NNP
cord-277648-9kxwkcbl	190	9	were	be	VBD
cord-277648-9kxwkcbl	190	10	strongly	strongly	RB
cord-277648-9kxwkcbl	190	11	differentially	differentially	RB
cord-277648-9kxwkcbl	190	12	expressed	express	VBN
cord-277648-9kxwkcbl	190	13	in	in	IN
cord-277648-9kxwkcbl	190	14	BALF	BALF	NNP
cord-277648-9kxwkcbl	190	15	MPs	MPs	NNPS
cord-277648-9kxwkcbl	190	16	during	during	IN
cord-277648-9kxwkcbl	190	17	severe	severe	JJ
cord-277648-9kxwkcbl	190	18	disease	disease	NN
cord-277648-9kxwkcbl	190	19	and	and	CC
cord-277648-9kxwkcbl	190	20	have	have	VBP
cord-277648-9kxwkcbl	190	21	been	be	VBN
cord-277648-9kxwkcbl	190	22	previously	previously	RB
cord-277648-9kxwkcbl	190	23	documented	document	VBN
cord-277648-9kxwkcbl	190	24	to	to	TO
cord-277648-9kxwkcbl	190	25	play	play	VB
cord-277648-9kxwkcbl	190	26	a	a	DT
cord-277648-9kxwkcbl	190	27	role	role	NN
cord-277648-9kxwkcbl	190	28	in	in	IN
cord-277648-9kxwkcbl	190	29	the	the	DT
cord-277648-9kxwkcbl	190	30	immune	immune	JJ
cord-277648-9kxwkcbl	190	31	response	response	NN
cord-277648-9kxwkcbl	190	32	to	to	IN
cord-277648-9kxwkcbl	190	33	respiratory	respiratory	JJ
cord-277648-9kxwkcbl	190	34	viral	viral	JJ
cord-277648-9kxwkcbl	190	35	infections	infection	NNS
cord-277648-9kxwkcbl	190	36	.	.	.
cord-277648-9kxwkcbl	191	1	TIMP1	TIMP1	NNP
cord-277648-9kxwkcbl	191	2	has	have	VBZ
cord-277648-9kxwkcbl	191	3	been	be	VBN
cord-277648-9kxwkcbl	191	4	shown	show	VBN
cord-277648-9kxwkcbl	191	5	to	to	TO
cord-277648-9kxwkcbl	191	6	promote	promote	VB
cord-277648-9kxwkcbl	191	7	deleterious	deleterious	JJ
cord-277648-9kxwkcbl	191	8	immune	immune	JJ
cord-277648-9kxwkcbl	191	9	responses	response	NNS
cord-277648-9kxwkcbl	191	10	in	in	IN
cord-277648-9kxwkcbl	191	11	the	the	DT
cord-277648-9kxwkcbl	191	12	lung	lung	NN
cord-277648-9kxwkcbl	191	13	during	during	IN
cord-277648-9kxwkcbl	191	14	murine	murine	JJ
cord-277648-9kxwkcbl	191	15	influenza	influenza	NN
cord-277648-9kxwkcbl	191	16	infection	infection	NN
cord-277648-9kxwkcbl	191	17	[	[	-LRB-
cord-277648-9kxwkcbl	191	18	48	48	CD
cord-277648-9kxwkcbl	191	19	]	]	-RRB-
cord-277648-9kxwkcbl	191	20	,	,	,
cord-277648-9kxwkcbl	191	21	VAMP5	VAMP5	NNP
cord-277648-9kxwkcbl	191	22	is	be	VBZ
cord-277648-9kxwkcbl	191	23	implicated	implicate	VBN
cord-277648-9kxwkcbl	191	24	in	in	IN
cord-277648-9kxwkcbl	191	25	signaling	signal	VBG
cord-277648-9kxwkcbl	191	26	pathways	pathway	NNS
cord-277648-9kxwkcbl	191	27	regulating	regulate	VBG
cord-277648-9kxwkcbl	191	28	influenza	influenza	NN
cord-277648-9kxwkcbl	191	29	viral	viral	JJ
cord-277648-9kxwkcbl	191	30	replication	replication	NN
cord-277648-9kxwkcbl	191	31	in	in	IN
cord-277648-9kxwkcbl	191	32	vitro	vitro	FW
cord-277648-9kxwkcbl	191	33	[	[	-LRB-
cord-277648-9kxwkcbl	191	34	48	48	CD
cord-277648-9kxwkcbl	191	35	,	,	,
cord-277648-9kxwkcbl	191	36	49	49	CD
cord-277648-9kxwkcbl	191	37	]	]	-RRB-
cord-277648-9kxwkcbl	191	38	,	,	,
cord-277648-9kxwkcbl	191	39	and	and	CC
cord-277648-9kxwkcbl	191	40	IL1R2	IL1R2	NNP
cord-277648-9kxwkcbl	191	41	encodes	encode	VBZ
cord-277648-9kxwkcbl	191	42	a	a	DT
cord-277648-9kxwkcbl	191	43	decoy	decoy	NN
cord-277648-9kxwkcbl	191	44	receptor	receptor	NN
cord-277648-9kxwkcbl	191	45	for	for	IN
cord-277648-9kxwkcbl	191	46	IL1-β	IL1-β	NNPS
cord-277648-9kxwkcbl	191	47	that	that	WDT
cord-277648-9kxwkcbl	191	48	is	be	VBZ
cord-277648-9kxwkcbl	191	49	upregulated	upregulate	VBN
cord-277648-9kxwkcbl	191	50	during	during	IN
cord-277648-9kxwkcbl	191	51	severe	severe	JJ
cord-277648-9kxwkcbl	191	52	influenza	influenza	NN
cord-277648-9kxwkcbl	191	53	[	[	-LRB-
cord-277648-9kxwkcbl	191	54	50	50	CD
cord-277648-9kxwkcbl	191	55	]	]	-RRB-
cord-277648-9kxwkcbl	191	56	.	.	.
cord-277648-9kxwkcbl	192	1	All	all	DT
cord-277648-9kxwkcbl	192	2	of	of	IN
cord-277648-9kxwkcbl	192	3	the	the	DT
cord-277648-9kxwkcbl	192	4	BALF	BALF	NNP
cord-277648-9kxwkcbl	192	5	identified	identify	VBD
cord-277648-9kxwkcbl	192	6	surface	surface	NN
cord-277648-9kxwkcbl	192	7	markers	marker	NNS
cord-277648-9kxwkcbl	192	8	in	in	IN
cord-277648-9kxwkcbl	192	9	Figure	figure	NN
cord-277648-9kxwkcbl	192	10	2C	2c	NN
cord-277648-9kxwkcbl	192	11	with	with	IN
cord-277648-9kxwkcbl	192	12	the	the	DT
cord-277648-9kxwkcbl	192	13	exception	exception	NN
cord-277648-9kxwkcbl	192	14	of	of	IN
cord-277648-9kxwkcbl	192	15	VAMP5	vamp5	NN
cord-277648-9kxwkcbl	192	16	,	,	,
cord-277648-9kxwkcbl	192	17	HLA	HLA	NNP
cord-277648-9kxwkcbl	192	18	-	-	HYPH
cord-277648-9kxwkcbl	192	19	DRA	DRA	NNP
cord-277648-9kxwkcbl	192	20	,	,	,
cord-277648-9kxwkcbl	192	21	and	and	CC
cord-277648-9kxwkcbl	192	22	CCR7	CCR7	NNP
cord-277648-9kxwkcbl	192	23	were	be	VBD
cord-277648-9kxwkcbl	192	24	specifically	specifically	RB
cord-277648-9kxwkcbl	192	25	differentially	differentially	RB
cord-277648-9kxwkcbl	192	26	expressed	express	VBN
cord-277648-9kxwkcbl	192	27	between	between	IN
cord-277648-9kxwkcbl	192	28	severe	severe	JJ
cord-277648-9kxwkcbl	192	29	and	and	CC
cord-277648-9kxwkcbl	192	30	moderate	moderate	JJ
cord-277648-9kxwkcbl	192	31	donors	donor	NNS
cord-277648-9kxwkcbl	192	32	but	but	CC
cord-277648-9kxwkcbl	192	33	not	not	RB
cord-277648-9kxwkcbl	192	34	between	between	IN
cord-277648-9kxwkcbl	192	35	moderate	moderate	JJ
cord-277648-9kxwkcbl	192	36	and	and	CC
cord-277648-9kxwkcbl	192	37	control	control	NN
cord-277648-9kxwkcbl	192	38	donors	donor	NNS
cord-277648-9kxwkcbl	192	39	(	(	-LRB-
cord-277648-9kxwkcbl	192	40	Figure	figure	NN
cord-277648-9kxwkcbl	192	41	S2B	S2B	NNP
cord-277648-9kxwkcbl	192	42	)	)	-RRB-
cord-277648-9kxwkcbl	192	43	.	.	.
cord-277648-9kxwkcbl	193	1	Investigating	investigate	VBG
cord-277648-9kxwkcbl	193	2	cell	cell	NN
cord-277648-9kxwkcbl	193	3	surface	surface	NN
cord-277648-9kxwkcbl	193	4	markers	marker	NNS
cord-277648-9kxwkcbl	193	5	in	in	IN
cord-277648-9kxwkcbl	193	6	PBMCs	pbmc	NNS
cord-277648-9kxwkcbl	193	7	,	,	,
cord-277648-9kxwkcbl	193	8	we	-PRON-	PRP
cord-277648-9kxwkcbl	193	9	found	find	VBD
cord-277648-9kxwkcbl	193	10	that	that	IN
cord-277648-9kxwkcbl	193	11	IL7R	il7r	NN
cord-277648-9kxwkcbl	193	12	on	on	IN
cord-277648-9kxwkcbl	193	13	NK	NK	NNP
cord-277648-9kxwkcbl	193	14	cells	cell	NNS
cord-277648-9kxwkcbl	193	15	as	as	RB
cord-277648-9kxwkcbl	193	16	well	well	RB
cord-277648-9kxwkcbl	193	17	as	as	IN
cord-277648-9kxwkcbl	193	18	S1PR1	S1PR1	NNP
cord-277648-9kxwkcbl	193	19	(	(	-LRB-
cord-277648-9kxwkcbl	193	20	CD363	CD363	NNP
cord-277648-9kxwkcbl	193	21	)	)	-RRB-
cord-277648-9kxwkcbl	193	22	on	on	IN
cord-277648-9kxwkcbl	193	23	γδ	γδ	NNP
cord-277648-9kxwkcbl	193	24	T	T	NNP
cord-277648-9kxwkcbl	193	25	cells	cell	NNS
cord-277648-9kxwkcbl	193	26	differentiate	differentiate	VBP
cord-277648-9kxwkcbl	193	27	ARDS	ARDS	NNP
cord-277648-9kxwkcbl	193	28	from	from	IN
cord-277648-9kxwkcbl	193	29	non	non	JJ
cord-277648-9kxwkcbl	193	30	-	-	NNP
cord-277648-9kxwkcbl	193	31	ARDS	ARDS	NNP
cord-277648-9kxwkcbl	193	32	COVID-19	covid-19	CC
cord-277648-9kxwkcbl	193	33	blood	blood	NN
cord-277648-9kxwkcbl	193	34	samples	sample	NNS
cord-277648-9kxwkcbl	193	35	.	.	.
cord-277648-9kxwkcbl	194	1	IL-7	il-7	JJ
cord-277648-9kxwkcbl	194	2	stimulation	stimulation	NN
cord-277648-9kxwkcbl	194	3	through	through	IN
cord-277648-9kxwkcbl	194	4	IL-7R	IL-7R	NNP
cord-277648-9kxwkcbl	194	5	has	have	VBZ
cord-277648-9kxwkcbl	194	6	been	be	VBN
cord-277648-9kxwkcbl	194	7	shown	show	VBN
cord-277648-9kxwkcbl	194	8	to	to	TO
cord-277648-9kxwkcbl	194	9	promote	promote	VB
cord-277648-9kxwkcbl	194	10	NK	NK	NNP
cord-277648-9kxwkcbl	194	11	cell	cell	NN
cord-277648-9kxwkcbl	194	12	survival	survival	NN
cord-277648-9kxwkcbl	194	13	by	by	IN
cord-277648-9kxwkcbl	194	14	inhibiting	inhibit	VBG
cord-277648-9kxwkcbl	194	15	apoptosis	apoptosis	NN
cord-277648-9kxwkcbl	194	16	[	[	-LRB-
cord-277648-9kxwkcbl	194	17	50	50	CD
cord-277648-9kxwkcbl	194	18	,	,	,
cord-277648-9kxwkcbl	194	19	51	51	CD
cord-277648-9kxwkcbl	194	20	]	]	-RRB-
cord-277648-9kxwkcbl	194	21	.	.	.
cord-277648-9kxwkcbl	195	1	S1PR1	S1PR1	NNP
cord-277648-9kxwkcbl	195	2	is	be	VBZ
cord-277648-9kxwkcbl	195	3	a	a	DT
cord-277648-9kxwkcbl	195	4	particularly	particularly	RB
cord-277648-9kxwkcbl	195	5	interesting	interesting	JJ
cord-277648-9kxwkcbl	195	6	marker	marker	NN
cord-277648-9kxwkcbl	195	7	due	due	IN
cord-277648-9kxwkcbl	195	8	to	to	IN
cord-277648-9kxwkcbl	195	9	previous	previous	JJ
cord-277648-9kxwkcbl	195	10	literature	literature	NN
cord-277648-9kxwkcbl	195	11	documenting	document	VBG
cord-277648-9kxwkcbl	195	12	its	-PRON-	PRP$
cord-277648-9kxwkcbl	195	13	role	role	NN
cord-277648-9kxwkcbl	195	14	in	in	IN
cord-277648-9kxwkcbl	195	15	stimulating	stimulate	VBG
cord-277648-9kxwkcbl	195	16	highly	highly	RB
cord-277648-9kxwkcbl	195	17	inflammatory	inflammatory	JJ
cord-277648-9kxwkcbl	195	18	pathways	pathway	NNS
cord-277648-9kxwkcbl	195	19	such	such	JJ
cord-277648-9kxwkcbl	195	20	as	as	IN
cord-277648-9kxwkcbl	195	21	JAK	JAK	NNP
cord-277648-9kxwkcbl	195	22	/	/	SYM
cord-277648-9kxwkcbl	195	23	STAT	STAT	NNP
cord-277648-9kxwkcbl	195	24	and	and	CC
cord-277648-9kxwkcbl	195	25	mTOR/	mTOR/	NNP
cord-277648-9kxwkcbl	196	1	PI3K	PI3K	NNP
cord-277648-9kxwkcbl	196	2	/	/	SYM
cord-277648-9kxwkcbl	196	3	Akt	Akt	NNP
cord-277648-9kxwkcbl	196	4	.	.	.
cord-277648-9kxwkcbl	197	1	Additionally	additionally	RB
cord-277648-9kxwkcbl	197	2	,	,	,
cord-277648-9kxwkcbl	197	3	suppression	suppression	NN
cord-277648-9kxwkcbl	197	4	of	of	IN
cord-277648-9kxwkcbl	197	5	the	the	DT
cord-277648-9kxwkcbl	197	6	S1PR1	S1PR1	NNP
cord-277648-9kxwkcbl	197	7	cognate	cognate	NN
cord-277648-9kxwkcbl	197	8	ligand	ligand	NN
cord-277648-9kxwkcbl	197	9	S1P1	S1P1	NNP
cord-277648-9kxwkcbl	197	10	decreased	decrease	VBD
cord-277648-9kxwkcbl	197	11	mortality	mortality	NN
cord-277648-9kxwkcbl	197	12	rates	rate	NNS
cord-277648-9kxwkcbl	197	13	during	during	IN
cord-277648-9kxwkcbl	197	14	influenza	influenza	NN
cord-277648-9kxwkcbl	197	15	infection	infection	NN
cord-277648-9kxwkcbl	197	16	in	in	IN
cord-277648-9kxwkcbl	197	17	mice	mouse	NNS
cord-277648-9kxwkcbl	197	18	[	[	-LRB-
cord-277648-9kxwkcbl	197	19	41	41	CD
cord-277648-9kxwkcbl	197	20	,	,	,
cord-277648-9kxwkcbl	197	21	42	42	CD
cord-277648-9kxwkcbl	197	22	,	,	,
cord-277648-9kxwkcbl	197	23	52	52	CD
cord-277648-9kxwkcbl	197	24	]	]	-RRB-
cord-277648-9kxwkcbl	197	25	.	.	.
cord-277648-9kxwkcbl	198	1	All	all	DT
cord-277648-9kxwkcbl	198	2	of	of	IN
cord-277648-9kxwkcbl	198	3	the	the	DT
cord-277648-9kxwkcbl	198	4	identified	identify	VBN
cord-277648-9kxwkcbl	198	5	PBMC	PBMC	NNP
cord-277648-9kxwkcbl	198	6	surface	surface	NN
cord-277648-9kxwkcbl	198	7	markers	marker	NNS
cord-277648-9kxwkcbl	198	8	in	in	IN
cord-277648-9kxwkcbl	198	9	Figure	figure	NN
cord-277648-9kxwkcbl	198	10	2F	2f	NN
cord-277648-9kxwkcbl	198	11	were	be	VBD
cord-277648-9kxwkcbl	198	12	specifically	specifically	RB
cord-277648-9kxwkcbl	198	13	differentially	differentially	RB
cord-277648-9kxwkcbl	198	14	expressed	express	VBN
cord-277648-9kxwkcbl	198	15	between	between	IN
cord-277648-9kxwkcbl	198	16	ARDS	ARDS	NNP
cord-277648-9kxwkcbl	198	17	and	and	CC
cord-277648-9kxwkcbl	198	18	non	non	NNP
cord-277648-9kxwkcbl	198	19	-	-	JJ
cord-277648-9kxwkcbl	198	20	ARDS	ARDS	NNP
cord-277648-9kxwkcbl	198	21	donors	donor	NNS
cord-277648-9kxwkcbl	198	22	but	but	CC
cord-277648-9kxwkcbl	198	23	not	not	RB
cord-277648-9kxwkcbl	198	24	between	between	IN
cord-277648-9kxwkcbl	198	25	non	non	JJ
cord-277648-9kxwkcbl	198	26	-	-	JJ
cord-277648-9kxwkcbl	198	27	ARDS	ARDS	NNP
cord-277648-9kxwkcbl	198	28	and	and	CC
cord-277648-9kxwkcbl	198	29	control	control	NN
cord-277648-9kxwkcbl	198	30	donors	donor	NNS
cord-277648-9kxwkcbl	198	31	(	(	-LRB-
cord-277648-9kxwkcbl	198	32	Figure	figure	NN
cord-277648-9kxwkcbl	198	33	  	  	_SP
cord-277648-9kxwkcbl	198	34	S2E	s2e	NN
cord-277648-9kxwkcbl	198	35	)	)	-RRB-
cord-277648-9kxwkcbl	198	36	.	.	.
cord-277648-9kxwkcbl	199	1	Our	-PRON-	PRP$
cord-277648-9kxwkcbl	199	2	investigation	investigation	NN
cord-277648-9kxwkcbl	199	3	revealed	reveal	VBD
cord-277648-9kxwkcbl	199	4	a	a	DT
cord-277648-9kxwkcbl	199	5	small	small	JJ
cord-277648-9kxwkcbl	199	6	number	number	NN
cord-277648-9kxwkcbl	199	7	of	of	IN
cord-277648-9kxwkcbl	199	8	common	common	JJ
cord-277648-9kxwkcbl	199	9	surface	surface	NN
cord-277648-9kxwkcbl	199	10	markers	marker	NNS
cord-277648-9kxwkcbl	199	11	of	of	IN
cord-277648-9kxwkcbl	199	12	interest	interest	NN
cord-277648-9kxwkcbl	199	13	between	between	IN
cord-277648-9kxwkcbl	199	14	BALF	BALF	NNP
cord-277648-9kxwkcbl	199	15	and	and	CC
cord-277648-9kxwkcbl	199	16	PBMC	PBMC	NNP
cord-277648-9kxwkcbl	199	17	samples	sample	NNS
cord-277648-9kxwkcbl	199	18	,	,	,
cord-277648-9kxwkcbl	199	19	namely	namely	RB
cord-277648-9kxwkcbl	199	20	HLADQA1	HLADQA1	NNP
cord-277648-9kxwkcbl	199	21	and	and	CC
cord-277648-9kxwkcbl	199	22	HLADQA2	HLADQA2	NNP
cord-277648-9kxwkcbl	199	23	on	on	IN
cord-277648-9kxwkcbl	199	24	MPs	MPs	NNPS
cord-277648-9kxwkcbl	199	25	/	/	SYM
cord-277648-9kxwkcbl	199	26	CD16	CD16	NNP
cord-277648-9kxwkcbl	199	27	+	+	CC
cord-277648-9kxwkcbl	199	28	monocytes	monocyte	NNS
cord-277648-9kxwkcbl	199	29	and	and	CC
cord-277648-9kxwkcbl	199	30	HLADRA	HLADRA	NNP
cord-277648-9kxwkcbl	199	31	on	on	IN
cord-277648-9kxwkcbl	199	32	MPs	MPs	NNPS
cord-277648-9kxwkcbl	199	33	/	/	SYM
cord-277648-9kxwkcbl	199	34	CD14	CD14	NNP
cord-277648-9kxwkcbl	199	35	+	+	CC
cord-277648-9kxwkcbl	199	36	monocytes	monocyte	NNS
cord-277648-9kxwkcbl	199	37	;	;	:
cord-277648-9kxwkcbl	199	38	these	these	DT
cord-277648-9kxwkcbl	199	39	HLA	HLA	NNP
cord-277648-9kxwkcbl	199	40	class	class	NN
cord-277648-9kxwkcbl	199	41	II	II	NNP
cord-277648-9kxwkcbl	199	42	transcripts	transcript	NNS
cord-277648-9kxwkcbl	199	43	are	be	VBP
cord-277648-9kxwkcbl	199	44	downregulated	downregulate	VBN
cord-277648-9kxwkcbl	199	45	with	with	IN
cord-277648-9kxwkcbl	199	46	increasing	increase	VBG
cord-277648-9kxwkcbl	199	47	severity	severity	NN
cord-277648-9kxwkcbl	199	48	level	level	NN
cord-277648-9kxwkcbl	199	49	in	in	IN
cord-277648-9kxwkcbl	199	50	both	both	DT
cord-277648-9kxwkcbl	199	51	compartments	compartment	NNS
cord-277648-9kxwkcbl	199	52	.	.	.
cord-277648-9kxwkcbl	200	1	Similar	similar	JJ
cord-277648-9kxwkcbl	200	2	observations	observation	NNS
cord-277648-9kxwkcbl	200	3	of	of	IN
cord-277648-9kxwkcbl	200	4	a	a	DT
cord-277648-9kxwkcbl	200	5	severity	severity	NN
cord-277648-9kxwkcbl	200	6	-	-	HYPH
cord-277648-9kxwkcbl	200	7	specific	specific	JJ
cord-277648-9kxwkcbl	200	8	loss	loss	NN
cord-277648-9kxwkcbl	200	9	of	of	IN
cord-277648-9kxwkcbl	200	10	HLA	HLA	NNP
cord-277648-9kxwkcbl	200	11	-	-	HYPH
cord-277648-9kxwkcbl	200	12	DR	DR	NNP
cord-277648-9kxwkcbl	200	13	on	on	IN
cord-277648-9kxwkcbl	200	14	CD14	CD14	NNP
cord-277648-9kxwkcbl	200	15	+	+	CC
cord-277648-9kxwkcbl	200	16	monocytes	monocyte	NNS
cord-277648-9kxwkcbl	200	17	and	and	CC
cord-277648-9kxwkcbl	200	18	T	t	NN
cord-277648-9kxwkcbl	200	19	cells	cell	NNS
cord-277648-9kxwkcbl	200	20	have	have	VBP
cord-277648-9kxwkcbl	200	21	been	be	VBN
cord-277648-9kxwkcbl	200	22	previously	previously	RB
cord-277648-9kxwkcbl	200	23	observed	observe	VBN
cord-277648-9kxwkcbl	200	24	in	in	IN
cord-277648-9kxwkcbl	200	25	recent	recent	JJ
cord-277648-9kxwkcbl	200	26	scRNA	scRNA	NNS
cord-277648-9kxwkcbl	200	27	-	-	HYPH
cord-277648-9kxwkcbl	200	28	seq	seq	NN
cord-277648-9kxwkcbl	200	29	and	and	CC
cord-277648-9kxwkcbl	200	30	flow	flow	VB
cord-277648-9kxwkcbl	200	31	cytometry	cytometry	NN
cord-277648-9kxwkcbl	200	32	studies	study	NNS
cord-277648-9kxwkcbl	200	33	[	[	-LRB-
cord-277648-9kxwkcbl	200	34	29	29	CD
cord-277648-9kxwkcbl	200	35	,	,	,
cord-277648-9kxwkcbl	200	36	30	30	CD
cord-277648-9kxwkcbl	200	37	,	,	,
cord-277648-9kxwkcbl	200	38	31	31	CD
cord-277648-9kxwkcbl	200	39	,	,	,
cord-277648-9kxwkcbl	200	40	32	32	CD
cord-277648-9kxwkcbl	200	41	,	,	,
cord-277648-9kxwkcbl	200	42	34	34	CD
cord-277648-9kxwkcbl	200	43	,	,	,
cord-277648-9kxwkcbl	200	44	36	36	CD
cord-277648-9kxwkcbl	200	45	]	]	-RRB-
cord-277648-9kxwkcbl	200	46	.	.	.
cord-277648-9kxwkcbl	201	1	Together	together	RB
cord-277648-9kxwkcbl	201	2	,	,	,
cord-277648-9kxwkcbl	201	3	these	these	DT
cord-277648-9kxwkcbl	201	4	findings	finding	NNS
cord-277648-9kxwkcbl	201	5	suggest	suggest	VBP
cord-277648-9kxwkcbl	201	6	transcripts	transcript	NNS
cord-277648-9kxwkcbl	201	7	that	that	WDT
cord-277648-9kxwkcbl	201	8	should	should	MD
cord-277648-9kxwkcbl	201	9	be	be	VB
cord-277648-9kxwkcbl	201	10	studied	study	VBN
cord-277648-9kxwkcbl	201	11	further	further	RB
cord-277648-9kxwkcbl	201	12	at	at	IN
cord-277648-9kxwkcbl	201	13	the	the	DT
cord-277648-9kxwkcbl	201	14	protein	protein	NN
cord-277648-9kxwkcbl	201	15	level	level	NN
cord-277648-9kxwkcbl	201	16	as	as	IN
cord-277648-9kxwkcbl	201	17	potential	potential	JJ
cord-277648-9kxwkcbl	201	18	markers	marker	NNS
cord-277648-9kxwkcbl	201	19	of	of	IN
cord-277648-9kxwkcbl	201	20	a	a	DT
cord-277648-9kxwkcbl	201	21	severe	severe	JJ
cord-277648-9kxwkcbl	201	22	or	or	CC
cord-277648-9kxwkcbl	201	23	ARDS	ARDS	NNP
cord-277648-9kxwkcbl	201	24	disease	disease	NN
cord-277648-9kxwkcbl	201	25	course	course	NN
cord-277648-9kxwkcbl	201	26	for	for	IN
cord-277648-9kxwkcbl	201	27	immunophenotyping	immunophenotype	VBG
cord-277648-9kxwkcbl	201	28	patients	patient	NNS
cord-277648-9kxwkcbl	201	29	through	through	IN
cord-277648-9kxwkcbl	201	30	BALF	BALF	NNP
cord-277648-9kxwkcbl	201	31	sampling	sampling	NN
cord-277648-9kxwkcbl	201	32	or	or	CC
cord-277648-9kxwkcbl	201	33	a	a	DT
cord-277648-9kxwkcbl	201	34	convenient	convenient	JJ
cord-277648-9kxwkcbl	201	35	blood	blood	NN
cord-277648-9kxwkcbl	201	36	draw	draw	NN
cord-277648-9kxwkcbl	201	37	.	.	.
cord-277648-9kxwkcbl	202	1	Cell	cell	NN
cord-277648-9kxwkcbl	202	2	type	type	NN
cord-277648-9kxwkcbl	202	3	-	-	HYPH
cord-277648-9kxwkcbl	202	4	specific	specific	JJ
cord-277648-9kxwkcbl	202	5	immunopathological	immunopathological	JJ
cord-277648-9kxwkcbl	202	6	responses	response	NNS
cord-277648-9kxwkcbl	202	7	in	in	IN
cord-277648-9kxwkcbl	202	8	severe	severe	JJ
cord-277648-9kxwkcbl	202	9	COVID-19	covid-19	NN
cord-277648-9kxwkcbl	202	10	have	have	VBP
cord-277648-9kxwkcbl	202	11	been	be	VBN
cord-277648-9kxwkcbl	202	12	investigated	investigate	VBN
cord-277648-9kxwkcbl	202	13	at	at	IN
cord-277648-9kxwkcbl	202	14	both	both	CC
cord-277648-9kxwkcbl	202	15	local	local	JJ
cord-277648-9kxwkcbl	202	16	and	and	CC
cord-277648-9kxwkcbl	202	17	systemic	systemic	JJ
cord-277648-9kxwkcbl	202	18	levels	level	NNS
cord-277648-9kxwkcbl	202	19	in	in	IN
cord-277648-9kxwkcbl	202	20	recent	recent	JJ
cord-277648-9kxwkcbl	202	21	studies	study	NNS
cord-277648-9kxwkcbl	202	22	comparing	compare	VBG
cord-277648-9kxwkcbl	202	23	severe	severe	JJ
cord-277648-9kxwkcbl	202	24	patients	patient	NNS
cord-277648-9kxwkcbl	202	25	to	to	IN
cord-277648-9kxwkcbl	202	26	healthy	healthy	JJ
cord-277648-9kxwkcbl	202	27	controls	control	NNS
cord-277648-9kxwkcbl	202	28	[	[	-LRB-
cord-277648-9kxwkcbl	202	29	21	21	CD
cord-277648-9kxwkcbl	202	30	,	,	,
cord-277648-9kxwkcbl	202	31	22	22	CD
cord-277648-9kxwkcbl	202	32	,	,	,
cord-277648-9kxwkcbl	202	33	23	23	CD
cord-277648-9kxwkcbl	202	34	,	,	,
cord-277648-9kxwkcbl	202	35	24	24	CD
cord-277648-9kxwkcbl	202	36	,	,	,
cord-277648-9kxwkcbl	202	37	25	25	CD
cord-277648-9kxwkcbl	202	38	,	,	,
cord-277648-9kxwkcbl	202	39	26	26	CD
cord-277648-9kxwkcbl	202	40	,	,	,
cord-277648-9kxwkcbl	202	41	32	32	CD
cord-277648-9kxwkcbl	202	42	,	,	,
cord-277648-9kxwkcbl	202	43	53	53	CD
cord-277648-9kxwkcbl	202	44	,	,	,
cord-277648-9kxwkcbl	202	45	54	54	CD
cord-277648-9kxwkcbl	202	46	,	,	,
cord-277648-9kxwkcbl	202	47	55	55	CD
cord-277648-9kxwkcbl	202	48	]	]	-RRB-
cord-277648-9kxwkcbl	202	49	.	.	.
cord-277648-9kxwkcbl	203	1	We	-PRON-	PRP
cord-277648-9kxwkcbl	203	2	sought	seek	VBD
cord-277648-9kxwkcbl	203	3	to	to	TO
cord-277648-9kxwkcbl	203	4	build	build	VB
cord-277648-9kxwkcbl	203	5	on	on	IN
cord-277648-9kxwkcbl	203	6	this	this	DT
cord-277648-9kxwkcbl	203	7	knowledge	knowledge	NN
cord-277648-9kxwkcbl	203	8	by	by	IN
cord-277648-9kxwkcbl	203	9	determining	determine	VBG
cord-277648-9kxwkcbl	203	10	the	the	DT
cord-277648-9kxwkcbl	203	11	cell	cell	NN
cord-277648-9kxwkcbl	203	12	-	-	HYPH
cord-277648-9kxwkcbl	203	13	type	type	NN
cord-277648-9kxwkcbl	203	14	specific	specific	JJ
cord-277648-9kxwkcbl	203	15	biological	biological	JJ
cord-277648-9kxwkcbl	203	16	responses	response	NNS
cord-277648-9kxwkcbl	203	17	that	that	WDT
cord-277648-9kxwkcbl	203	18	differentiate	differentiate	VBP
cord-277648-9kxwkcbl	203	19	more	more	RBR
cord-277648-9kxwkcbl	203	20	finely	finely	RB
cord-277648-9kxwkcbl	203	21	stratified	stratified	JJ
cord-277648-9kxwkcbl	203	22	disease	disease	NN
cord-277648-9kxwkcbl	203	23	severity	severity	NN
cord-277648-9kxwkcbl	203	24	levels	level	NNS
cord-277648-9kxwkcbl	203	25	in	in	IN
cord-277648-9kxwkcbl	203	26	the	the	DT
cord-277648-9kxwkcbl	203	27	lung	lung	NN
cord-277648-9kxwkcbl	203	28	and	and	CC
cord-277648-9kxwkcbl	203	29	systemic	systemic	JJ
cord-277648-9kxwkcbl	203	30	circulation	circulation	NN
cord-277648-9kxwkcbl	203	31	.	.	.
cord-277648-9kxwkcbl	204	1	In	in	IN
cord-277648-9kxwkcbl	204	2	myeloid	myeloid	JJ
cord-277648-9kxwkcbl	204	3	and	and	CC
cord-277648-9kxwkcbl	204	4	lymphoid	lymphoid	JJ
cord-277648-9kxwkcbl	204	5	cells	cell	NNS
cord-277648-9kxwkcbl	204	6	of	of	IN
cord-277648-9kxwkcbl	204	7	the	the	DT
cord-277648-9kxwkcbl	204	8	BALF	BALF	NNP
cord-277648-9kxwkcbl	204	9	,	,	,
cord-277648-9kxwkcbl	204	10	we	-PRON-	PRP
cord-277648-9kxwkcbl	204	11	observed	observe	VBD
cord-277648-9kxwkcbl	204	12	a	a	DT
cord-277648-9kxwkcbl	204	13	concerted	concerted	JJ
cord-277648-9kxwkcbl	204	14	enrichment	enrichment	NN
cord-277648-9kxwkcbl	204	15	of	of	IN
cord-277648-9kxwkcbl	204	16	the	the	DT
cord-277648-9kxwkcbl	204	17	TNFα	TNFα	NNS
cord-277648-9kxwkcbl	204	18	signaling	signal	VBG
cord-277648-9kxwkcbl	204	19	via	via	IN
cord-277648-9kxwkcbl	204	20	NF	nf	NN
cord-277648-9kxwkcbl	204	21	-	-	HYPH
cord-277648-9kxwkcbl	204	22	κB	κB	NNP
cord-277648-9kxwkcbl	204	23	pathway	pathway	NN
cord-277648-9kxwkcbl	204	24	in	in	IN
cord-277648-9kxwkcbl	204	25	severe	severe	JJ
cord-277648-9kxwkcbl	204	26	compared	compare	VBN
cord-277648-9kxwkcbl	204	27	to	to	IN
cord-277648-9kxwkcbl	204	28	moderate	moderate	JJ
cord-277648-9kxwkcbl	204	29	donors	donor	NNS
cord-277648-9kxwkcbl	204	30	,	,	,
cord-277648-9kxwkcbl	204	31	indicating	indicate	VBG
cord-277648-9kxwkcbl	204	32	the	the	DT
cord-277648-9kxwkcbl	204	33	upregulated	upregulated	JJ
cord-277648-9kxwkcbl	204	34	expression	expression	NN
cord-277648-9kxwkcbl	204	35	of	of	IN
cord-277648-9kxwkcbl	204	36	factors	factor	NNS
cord-277648-9kxwkcbl	204	37	such	such	JJ
cord-277648-9kxwkcbl	204	38	as	as	IN
cord-277648-9kxwkcbl	204	39	NFKBIA	NFKBIA	NNP
cord-277648-9kxwkcbl	204	40	and	and	CC
cord-277648-9kxwkcbl	204	41	TNFAIP3	TNFAIP3	NNS
cord-277648-9kxwkcbl	204	42	in	in	IN
cord-277648-9kxwkcbl	204	43	severe	severe	JJ
cord-277648-9kxwkcbl	204	44	disease	disease	NN
cord-277648-9kxwkcbl	204	45	.	.	.
cord-277648-9kxwkcbl	205	1	We	-PRON-	PRP
cord-277648-9kxwkcbl	205	2	further	further	RB
cord-277648-9kxwkcbl	205	3	noted	note	VBD
cord-277648-9kxwkcbl	205	4	IL-2	IL-2	NNP
cord-277648-9kxwkcbl	205	5	and	and	CC
cord-277648-9kxwkcbl	205	6	IL-6	IL-6	NNP
cord-277648-9kxwkcbl	205	7	signaling	signal	VBG
cord-277648-9kxwkcbl	205	8	pathway	pathway	NN
cord-277648-9kxwkcbl	205	9	enrichment	enrichment	NN
cord-277648-9kxwkcbl	205	10	in	in	IN
cord-277648-9kxwkcbl	205	11	cell	cell	NN
cord-277648-9kxwkcbl	205	12	types	type	NNS
cord-277648-9kxwkcbl	205	13	including	include	VBG
cord-277648-9kxwkcbl	205	14	MPs	mp	NNS
cord-277648-9kxwkcbl	205	15	,	,	,
cord-277648-9kxwkcbl	205	16	mast	mast	NN
cord-277648-9kxwkcbl	205	17	cells	cell	NNS
cord-277648-9kxwkcbl	205	18	,	,	,
cord-277648-9kxwkcbl	205	19	and	and	CC
cord-277648-9kxwkcbl	205	20	neutrophils	neutrophil	NNS
cord-277648-9kxwkcbl	205	21	.	.	.
cord-277648-9kxwkcbl	206	1	IL2RA	il2ra	NN
cord-277648-9kxwkcbl	206	2	expression	expression	NN
cord-277648-9kxwkcbl	206	3	was	be	VBD
cord-277648-9kxwkcbl	206	4	observed	observe	VBN
cord-277648-9kxwkcbl	206	5	in	in	IN
cord-277648-9kxwkcbl	206	6	mast	mast	NN
cord-277648-9kxwkcbl	206	7	cells	cell	NNS
cord-277648-9kxwkcbl	206	8	,	,	,
cord-277648-9kxwkcbl	206	9	IL6R	il6r	PRP
cord-277648-9kxwkcbl	206	10	was	be	VBD
cord-277648-9kxwkcbl	206	11	expressed	express	VBN
cord-277648-9kxwkcbl	206	12	in	in	IN
cord-277648-9kxwkcbl	206	13	MPs	MPs	NNP
cord-277648-9kxwkcbl	206	14	,	,	,
cord-277648-9kxwkcbl	206	15	mast	mast	NN
cord-277648-9kxwkcbl	206	16	cells	cell	NNS
cord-277648-9kxwkcbl	206	17	and	and	CC
cord-277648-9kxwkcbl	206	18	neutrophils	neutrophil	NNS
cord-277648-9kxwkcbl	206	19	,	,	,
cord-277648-9kxwkcbl	206	20	and	and	CC
cord-277648-9kxwkcbl	206	21	neither	neither	CC
cord-277648-9kxwkcbl	206	22	the	the	DT
cord-277648-9kxwkcbl	206	23	IL2	IL2	NNP
cord-277648-9kxwkcbl	206	24	nor	nor	CC
cord-277648-9kxwkcbl	206	25	IL6	il6	NN
cord-277648-9kxwkcbl	206	26	transcripts	transcript	NNS
cord-277648-9kxwkcbl	206	27	were	be	VBD
cord-277648-9kxwkcbl	206	28	well	well	RB
cord-277648-9kxwkcbl	206	29	-	-	HYPH
cord-277648-9kxwkcbl	206	30	captured	capture	VBN
cord-277648-9kxwkcbl	206	31	in	in	IN
cord-277648-9kxwkcbl	206	32	the	the	DT
cord-277648-9kxwkcbl	206	33	dataset	dataset	NN
cord-277648-9kxwkcbl	206	34	.	.	.
cord-277648-9kxwkcbl	207	1	IFN	IFN	NNP
cord-277648-9kxwkcbl	207	2	-	-	HYPH
cord-277648-9kxwkcbl	207	3	α	α	NNP
cord-277648-9kxwkcbl	207	4	(	(	-LRB-
cord-277648-9kxwkcbl	207	5	type	type	NN
cord-277648-9kxwkcbl	207	6	I	I	NNP
cord-277648-9kxwkcbl	207	7	)	)	-RRB-
cord-277648-9kxwkcbl	207	8	and	and	CC
cord-277648-9kxwkcbl	207	9	IFN	IFN	NNP
cord-277648-9kxwkcbl	207	10	-	-	HYPH
cord-277648-9kxwkcbl	207	11	γ	γ	NNP
cord-277648-9kxwkcbl	207	12	(	(	-LRB-
cord-277648-9kxwkcbl	207	13	type	type	NN
cord-277648-9kxwkcbl	207	14	II	II	NNP
cord-277648-9kxwkcbl	207	15	)	)	-RRB-
cord-277648-9kxwkcbl	208	1	pathway	pathway	NN
cord-277648-9kxwkcbl	208	2	responses	response	NNS
cord-277648-9kxwkcbl	208	3	showed	show	VBD
cord-277648-9kxwkcbl	208	4	mixed	mixed	JJ
cord-277648-9kxwkcbl	208	5	enrichment	enrichment	NN
cord-277648-9kxwkcbl	208	6	and	and	CC
cord-277648-9kxwkcbl	208	7	depletion	depletion	NN
cord-277648-9kxwkcbl	208	8	,	,	,
cord-277648-9kxwkcbl	208	9	with	with	IN
cord-277648-9kxwkcbl	208	10	type	type	NN
cord-277648-9kxwkcbl	208	11	I	-PRON-	PRP
cord-277648-9kxwkcbl	208	12	and	and	CC
cord-277648-9kxwkcbl	208	13	II	II	NNP
cord-277648-9kxwkcbl	208	14	interferon	interferon	NN
cord-277648-9kxwkcbl	208	15	signaling	signal	VBG
cord-277648-9kxwkcbl	208	16	apparently	apparently	RB
cord-277648-9kxwkcbl	208	17	decreased	decrease	VBD
cord-277648-9kxwkcbl	208	18	in	in	IN
cord-277648-9kxwkcbl	208	19	a	a	DT
cord-277648-9kxwkcbl	208	20	majority	majority	NN
cord-277648-9kxwkcbl	208	21	of	of	IN
cord-277648-9kxwkcbl	208	22	BALF	BALF	NNP
cord-277648-9kxwkcbl	208	23	T	T	NNP
cord-277648-9kxwkcbl	208	24	cell	cell	NN
cord-277648-9kxwkcbl	208	25	subtypes	subtype	NNS
cord-277648-9kxwkcbl	208	26	.	.	.
cord-277648-9kxwkcbl	209	1	These	these	DT
cord-277648-9kxwkcbl	209	2	data	datum	NNS
cord-277648-9kxwkcbl	209	3	are	be	VBP
cord-277648-9kxwkcbl	209	4	consistent	consistent	JJ
cord-277648-9kxwkcbl	209	5	with	with	IN
cord-277648-9kxwkcbl	209	6	previous	previous	JJ
cord-277648-9kxwkcbl	209	7	observations	observation	NNS
cord-277648-9kxwkcbl	209	8	of	of	IN
cord-277648-9kxwkcbl	209	9	low	low	JJ
cord-277648-9kxwkcbl	209	10	expression	expression	NN
cord-277648-9kxwkcbl	209	11	of	of	IN
cord-277648-9kxwkcbl	209	12	IFNG	IFNG	NNP
cord-277648-9kxwkcbl	209	13	and	and	CC
cord-277648-9kxwkcbl	209	14	TNF	TNF	NNP
cord-277648-9kxwkcbl	209	15	in	in	IN
cord-277648-9kxwkcbl	209	16	cytotoxic	cytotoxic	JJ
cord-277648-9kxwkcbl	209	17	T	t	NN
cord-277648-9kxwkcbl	209	18	lymphocytes	lymphocyte	NNS
cord-277648-9kxwkcbl	209	19	of	of	IN
cord-277648-9kxwkcbl	209	20	BALF	BALF	NNP
cord-277648-9kxwkcbl	209	21	derived	derive	VBN
cord-277648-9kxwkcbl	209	22	from	from	IN
cord-277648-9kxwkcbl	209	23	severe	severe	JJ
cord-277648-9kxwkcbl	209	24	patients	patient	NNS
cord-277648-9kxwkcbl	209	25	[	[	-LRB-
cord-277648-9kxwkcbl	209	26	28	28	CD
cord-277648-9kxwkcbl	209	27	]	]	-RRB-
cord-277648-9kxwkcbl	209	28	.	.	.
cord-277648-9kxwkcbl	210	1	MPs	mp	NNS
cord-277648-9kxwkcbl	210	2	in	in	IN
cord-277648-9kxwkcbl	210	3	the	the	DT
cord-277648-9kxwkcbl	210	4	BALF	BALF	NNP
cord-277648-9kxwkcbl	210	5	demonstrated	demonstrate	VBD
cord-277648-9kxwkcbl	210	6	a	a	DT
cord-277648-9kxwkcbl	210	7	nearly	nearly	RB
cord-277648-9kxwkcbl	210	8	homogenous	homogenous	JJ
cord-277648-9kxwkcbl	210	9	enrichment	enrichment	NN
cord-277648-9kxwkcbl	210	10	of	of	IN
cord-277648-9kxwkcbl	210	11	the	the	DT
cord-277648-9kxwkcbl	210	12	IL-6	IL-6	NNP
cord-277648-9kxwkcbl	210	13	,	,	,
cord-277648-9kxwkcbl	210	14	IL-2	IL-2	NNP
cord-277648-9kxwkcbl	210	15	,	,	,
cord-277648-9kxwkcbl	210	16	and	and	CC
cord-277648-9kxwkcbl	210	17	TNF	TNF	NNP
cord-277648-9kxwkcbl	210	18	-	-	HYPH
cord-277648-9kxwkcbl	210	19	α	α	NNP
cord-277648-9kxwkcbl	210	20	signaling	signal	VBG
cord-277648-9kxwkcbl	210	21	via	via	IN
cord-277648-9kxwkcbl	210	22	NF	nf	NN
cord-277648-9kxwkcbl	210	23	-	-	HYPH
cord-277648-9kxwkcbl	210	24	κB	κB	NNP
cord-277648-9kxwkcbl	210	25	pathways	pathway	NNS
cord-277648-9kxwkcbl	210	26	across	across	IN
cord-277648-9kxwkcbl	210	27	the	the	DT
cord-277648-9kxwkcbl	210	28	diversity	diversity	NN
cord-277648-9kxwkcbl	210	29	of	of	IN
cord-277648-9kxwkcbl	210	30	clusters	cluster	NNS
cord-277648-9kxwkcbl	210	31	.	.	.
cord-277648-9kxwkcbl	211	1	When	when	WRB
cord-277648-9kxwkcbl	211	2	we	-PRON-	PRP
cord-277648-9kxwkcbl	211	3	compared	compare	VBD
cord-277648-9kxwkcbl	211	4	disease	disease	NN
cord-277648-9kxwkcbl	211	5	strata	strata	NN
cord-277648-9kxwkcbl	211	6	based	base	VBN
cord-277648-9kxwkcbl	211	7	on	on	IN
cord-277648-9kxwkcbl	211	8	ARDS	ARDS	NNP
cord-277648-9kxwkcbl	211	9	diagnosis	diagnosis	NN
cord-277648-9kxwkcbl	211	10	in	in	IN
cord-277648-9kxwkcbl	211	11	PBMCs	pbmc	NNS
cord-277648-9kxwkcbl	211	12	,	,	,
cord-277648-9kxwkcbl	211	13	fewer	few	JJR
cord-277648-9kxwkcbl	211	14	pathways	pathway	NNS
cord-277648-9kxwkcbl	211	15	demonstrate	demonstrate	VBP
cord-277648-9kxwkcbl	211	16	enrichment	enrichment	NN
cord-277648-9kxwkcbl	211	17	with	with	IN
cord-277648-9kxwkcbl	211	18	increasing	increase	VBG
cord-277648-9kxwkcbl	211	19	disease	disease	NN
cord-277648-9kxwkcbl	211	20	severity	severity	NN
cord-277648-9kxwkcbl	211	21	.	.	.
cord-277648-9kxwkcbl	212	1	Nevertheless	nevertheless	RB
cord-277648-9kxwkcbl	212	2	,	,	,
cord-277648-9kxwkcbl	212	3	a	a	DT
cord-277648-9kxwkcbl	212	4	striking	striking	JJ
cord-277648-9kxwkcbl	212	5	depletion	depletion	NN
cord-277648-9kxwkcbl	212	6	of	of	IN
cord-277648-9kxwkcbl	212	7	the	the	DT
cord-277648-9kxwkcbl	212	8	type	type	NN
cord-277648-9kxwkcbl	212	9	II	II	NNP
cord-277648-9kxwkcbl	213	1	interferon	interferon	NNP
cord-277648-9kxwkcbl	213	2	response	response	NN
cord-277648-9kxwkcbl	213	3	was	be	VBD
cord-277648-9kxwkcbl	213	4	observed	observe	VBN
cord-277648-9kxwkcbl	213	5	in	in	IN
cord-277648-9kxwkcbl	213	6	nearly	nearly	RB
cord-277648-9kxwkcbl	213	7	every	every	DT
cord-277648-9kxwkcbl	213	8	cell	cell	NN
cord-277648-9kxwkcbl	213	9	type	type	NN
cord-277648-9kxwkcbl	213	10	studied	study	VBN
cord-277648-9kxwkcbl	213	11	,	,	,
cord-277648-9kxwkcbl	213	12	along	along	IN
cord-277648-9kxwkcbl	213	13	with	with	IN
cord-277648-9kxwkcbl	213	14	a	a	DT
cord-277648-9kxwkcbl	213	15	broad	broad	JJ
cord-277648-9kxwkcbl	213	16	depletion	depletion	NN
cord-277648-9kxwkcbl	213	17	of	of	IN
cord-277648-9kxwkcbl	213	18	the	the	DT
cord-277648-9kxwkcbl	213	19	type	type	NN
cord-277648-9kxwkcbl	213	20	I	-PRON-	PRP
cord-277648-9kxwkcbl	213	21	interferon	interferon	VBD
cord-277648-9kxwkcbl	213	22	response	response	NN
cord-277648-9kxwkcbl	213	23	and	and	CC
cord-277648-9kxwkcbl	213	24	TNF	TNF	NNP
cord-277648-9kxwkcbl	213	25	-	-	HYPH
cord-277648-9kxwkcbl	213	26	α	α	NNP
cord-277648-9kxwkcbl	213	27	signaling	signal	VBG
cord-277648-9kxwkcbl	213	28	via	via	IN
cord-277648-9kxwkcbl	213	29	NF	nf	NN
cord-277648-9kxwkcbl	213	30	-	-	HYPH
cord-277648-9kxwkcbl	213	31	κB	κB	NNP
cord-277648-9kxwkcbl	213	32	pathways	pathway	NNS
cord-277648-9kxwkcbl	213	33	(	(	-LRB-
cord-277648-9kxwkcbl	213	34	including	include	VBG
cord-277648-9kxwkcbl	213	35	downregulation	downregulation	NN
cord-277648-9kxwkcbl	213	36	of	of	IN
cord-277648-9kxwkcbl	213	37	TNFAIP3	TNFAIP3	NNS
cord-277648-9kxwkcbl	213	38	and	and	CC
cord-277648-9kxwkcbl	213	39	NFKBIA	NFKBIA	NNP
cord-277648-9kxwkcbl	213	40	)	)	-RRB-
cord-277648-9kxwkcbl	213	41	.	.	.
cord-277648-9kxwkcbl	214	1	This	this	DT
cord-277648-9kxwkcbl	214	2	result	result	NN
cord-277648-9kxwkcbl	214	3	corroborates	corroborate	VBZ
cord-277648-9kxwkcbl	214	4	a	a	DT
cord-277648-9kxwkcbl	214	5	previously	previously	RB
cord-277648-9kxwkcbl	214	6	reported	report	VBN
cord-277648-9kxwkcbl	214	7	correlation	correlation	NN
cord-277648-9kxwkcbl	214	8	between	between	IN
cord-277648-9kxwkcbl	214	9	suppressed	suppress	VBN
cord-277648-9kxwkcbl	214	10	type	type	NN
cord-277648-9kxwkcbl	214	11	I	-PRON-	PRP
cord-277648-9kxwkcbl	214	12	and	and	CC
cord-277648-9kxwkcbl	214	13	II	II	NNP
cord-277648-9kxwkcbl	214	14	interferon	interferon	NN
cord-277648-9kxwkcbl	214	15	responses	response	NNS
cord-277648-9kxwkcbl	214	16	and	and	CC
cord-277648-9kxwkcbl	214	17	disease	disease	NN
cord-277648-9kxwkcbl	214	18	severity	severity	NN
cord-277648-9kxwkcbl	214	19	in	in	IN
cord-277648-9kxwkcbl	214	20	a	a	DT
cord-277648-9kxwkcbl	214	21	study	study	NN
cord-277648-9kxwkcbl	214	22	of	of	IN
cord-277648-9kxwkcbl	214	23	PBMCs	pbmc	NNS
cord-277648-9kxwkcbl	214	24	that	that	WDT
cord-277648-9kxwkcbl	214	25	was	be	VBD
cord-277648-9kxwkcbl	214	26	not	not	RB
cord-277648-9kxwkcbl	214	27	specific	specific	JJ
cord-277648-9kxwkcbl	214	28	to	to	IN
cord-277648-9kxwkcbl	214	29	cell	cell	NN
cord-277648-9kxwkcbl	214	30	type	type	NN
cord-277648-9kxwkcbl	214	31	[	[	-LRB-
cord-277648-9kxwkcbl	214	32	33	33	CD
cord-277648-9kxwkcbl	214	33	]	]	-RRB-
cord-277648-9kxwkcbl	214	34	,	,	,
cord-277648-9kxwkcbl	214	35	as	as	RB
cord-277648-9kxwkcbl	214	36	well	well	RB
cord-277648-9kxwkcbl	214	37	as	as	IN
cord-277648-9kxwkcbl	214	38	extending	extend	VBG
cord-277648-9kxwkcbl	214	39	findings	finding	NNS
cord-277648-9kxwkcbl	214	40	of	of	IN
cord-277648-9kxwkcbl	214	41	increased	increase	VBN
cord-277648-9kxwkcbl	214	42	interferon	interferon	NN
cord-277648-9kxwkcbl	214	43	response	response	NN
cord-277648-9kxwkcbl	214	44	in	in	IN
cord-277648-9kxwkcbl	214	45	monocytes	monocyte	NNS
cord-277648-9kxwkcbl	214	46	during	during	IN
cord-277648-9kxwkcbl	214	47	moderate	moderate	JJ
cord-277648-9kxwkcbl	214	48	disease	disease	NN
cord-277648-9kxwkcbl	214	49	but	but	CC
cord-277648-9kxwkcbl	214	50	not	not	RB
cord-277648-9kxwkcbl	214	51	severe	severe	JJ
cord-277648-9kxwkcbl	214	52	disease	disease	NN
cord-277648-9kxwkcbl	214	53	[	[	-LRB-
cord-277648-9kxwkcbl	214	54	34	34	CD
cord-277648-9kxwkcbl	214	55	,	,	,
cord-277648-9kxwkcbl	214	56	36	36	CD
cord-277648-9kxwkcbl	214	57	]	]	-RRB-
cord-277648-9kxwkcbl	214	58	.	.	.
cord-277648-9kxwkcbl	215	1	Our	-PRON-	PRP$
cord-277648-9kxwkcbl	215	2	findings	finding	NNS
cord-277648-9kxwkcbl	215	3	do	do	VBP
cord-277648-9kxwkcbl	215	4	not	not	RB
cord-277648-9kxwkcbl	215	5	preclude	preclude	VB
cord-277648-9kxwkcbl	215	6	the	the	DT
cord-277648-9kxwkcbl	215	7	observation	observation	NN
cord-277648-9kxwkcbl	215	8	of	of	IN
cord-277648-9kxwkcbl	215	9	increased	increase	VBN
cord-277648-9kxwkcbl	215	10	TNF	TNF	NNP
cord-277648-9kxwkcbl	215	11	-	-	HYPH
cord-277648-9kxwkcbl	215	12	α	α	NNP
cord-277648-9kxwkcbl	215	13	signaling	signal	VBG
cord-277648-9kxwkcbl	215	14	in	in	IN
cord-277648-9kxwkcbl	215	15	the	the	DT
cord-277648-9kxwkcbl	215	16	bloodstream	bloodstream	NN
cord-277648-9kxwkcbl	215	17	of	of	IN
cord-277648-9kxwkcbl	215	18	severe	severe	JJ
cord-277648-9kxwkcbl	215	19	and	and	CC
cord-277648-9kxwkcbl	215	20	critical	critical	JJ
cord-277648-9kxwkcbl	215	21	COVID-19	covid-19	CD
cord-277648-9kxwkcbl	215	22	patients	patient	NNS
cord-277648-9kxwkcbl	215	23	[	[	-LRB-
cord-277648-9kxwkcbl	215	24	33	33	CD
cord-277648-9kxwkcbl	215	25	]	]	-RRB-
cord-277648-9kxwkcbl	215	26	,	,	,
cord-277648-9kxwkcbl	215	27	as	as	IN
cord-277648-9kxwkcbl	215	28	TNFAIP3	tnfaip3	NN
cord-277648-9kxwkcbl	215	29	depletion	depletion	NN
cord-277648-9kxwkcbl	215	30	has	have	VBZ
cord-277648-9kxwkcbl	215	31	been	be	VBN
cord-277648-9kxwkcbl	215	32	shown	show	VBN
cord-277648-9kxwkcbl	215	33	to	to	TO
cord-277648-9kxwkcbl	215	34	cause	cause	VB
cord-277648-9kxwkcbl	215	35	increased	increase	VBN
cord-277648-9kxwkcbl	215	36	TNF	TNF	NNP
cord-277648-9kxwkcbl	215	37	-	-	HYPH
cord-277648-9kxwkcbl	215	38	α	α	NNP
cord-277648-9kxwkcbl	215	39	expression	expression	NN
cord-277648-9kxwkcbl	215	40	[	[	-LRB-
cord-277648-9kxwkcbl	215	41	56	56	CD
cord-277648-9kxwkcbl	215	42	]	]	-RRB-
cord-277648-9kxwkcbl	215	43	.	.	.
cord-277648-9kxwkcbl	216	1	We	-PRON-	PRP
cord-277648-9kxwkcbl	216	2	next	next	RB
cord-277648-9kxwkcbl	216	3	examined	examine	VBD
cord-277648-9kxwkcbl	216	4	the	the	DT
cord-277648-9kxwkcbl	216	5	similarity	similarity	NN
cord-277648-9kxwkcbl	216	6	of	of	IN
cord-277648-9kxwkcbl	216	7	pathway	pathway	NN
cord-277648-9kxwkcbl	216	8	-	-	HYPH
cord-277648-9kxwkcbl	216	9	level	level	NN
cord-277648-9kxwkcbl	216	10	changes	change	NNS
cord-277648-9kxwkcbl	216	11	across	across	IN
cord-277648-9kxwkcbl	216	12	the	the	DT
cord-277648-9kxwkcbl	216	13	severity	severity	NN
cord-277648-9kxwkcbl	216	14	stratifications	stratification	NNS
cord-277648-9kxwkcbl	216	15	provided	provide	VBN
cord-277648-9kxwkcbl	216	16	in	in	IN
cord-277648-9kxwkcbl	216	17	the	the	DT
cord-277648-9kxwkcbl	216	18	BALF	BALF	NNP
cord-277648-9kxwkcbl	216	19	and	and	CC
cord-277648-9kxwkcbl	216	20	PBMC	PBMC	NNP
cord-277648-9kxwkcbl	216	21	datasets	dataset	NNS
cord-277648-9kxwkcbl	216	22	.	.	.
cord-277648-9kxwkcbl	217	1	Comparing	compare	VBG
cord-277648-9kxwkcbl	217	2	BALF	BALF	NNP
cord-277648-9kxwkcbl	217	3	and	and	CC
cord-277648-9kxwkcbl	217	4	PBMC	PBMC	NNP
cord-277648-9kxwkcbl	217	5	responses	response	NNS
cord-277648-9kxwkcbl	217	6	to	to	IN
cord-277648-9kxwkcbl	217	7	increasing	increase	VBG
cord-277648-9kxwkcbl	217	8	disease	disease	NN
cord-277648-9kxwkcbl	217	9	severity	severity	NN
cord-277648-9kxwkcbl	217	10	level	level	NN
cord-277648-9kxwkcbl	217	11	in	in	IN
cord-277648-9kxwkcbl	217	12	consanguineous	consanguineous	JJ
cord-277648-9kxwkcbl	217	13	cell	cell	NN
cord-277648-9kxwkcbl	217	14	types	type	NNS
cord-277648-9kxwkcbl	217	15	showed	show	VBD
cord-277648-9kxwkcbl	217	16	shared	share	VBN
cord-277648-9kxwkcbl	217	17	suppression	suppression	NN
cord-277648-9kxwkcbl	217	18	of	of	IN
cord-277648-9kxwkcbl	217	19	the	the	DT
cord-277648-9kxwkcbl	217	20	type	type	NN
cord-277648-9kxwkcbl	218	1	I	-PRON-	PRP
cord-277648-9kxwkcbl	218	2	interferon	interferon	VBD
cord-277648-9kxwkcbl	218	3	response	response	NN
cord-277648-9kxwkcbl	218	4	in	in	IN
cord-277648-9kxwkcbl	218	5	CD4	CD4	NNP
cord-277648-9kxwkcbl	218	6	+	+	CC
cord-277648-9kxwkcbl	218	7	naive	naive	JJ
cord-277648-9kxwkcbl	218	8	,	,	,
cord-277648-9kxwkcbl	218	9	CD8	CD8	NNP
cord-277648-9kxwkcbl	218	10	+	+	CC
cord-277648-9kxwkcbl	218	11	effector	effector	NN
cord-277648-9kxwkcbl	218	12	,	,	,
cord-277648-9kxwkcbl	218	13	and	and	CC
cord-277648-9kxwkcbl	218	14	γδ	γδ	IN
cord-277648-9kxwkcbl	218	15	T	T	NNP
cord-277648-9kxwkcbl	218	16	cells	cell	NNS
cord-277648-9kxwkcbl	218	17	and	and	CC
cord-277648-9kxwkcbl	218	18	of	of	IN
cord-277648-9kxwkcbl	218	19	the	the	DT
cord-277648-9kxwkcbl	218	20	type	type	NN
cord-277648-9kxwkcbl	218	21	II	II	NNP
cord-277648-9kxwkcbl	219	1	interferon	interferon	NNP
cord-277648-9kxwkcbl	219	2	response	response	NN
cord-277648-9kxwkcbl	219	3	in	in	IN
cord-277648-9kxwkcbl	219	4	mature	mature	NNP
cord-277648-9kxwkcbl	219	5	B	B	NNP
cord-277648-9kxwkcbl	219	6	,	,	,
cord-277648-9kxwkcbl	219	7	proliferating	proliferate	VBG
cord-277648-9kxwkcbl	219	8	plasma	plasma	NN
cord-277648-9kxwkcbl	219	9	,	,	,
cord-277648-9kxwkcbl	219	10	CD4	CD4	NNP
cord-277648-9kxwkcbl	219	11	+	+	CC
cord-277648-9kxwkcbl	219	12	naive	naive	JJ
cord-277648-9kxwkcbl	219	13	,	,	,
cord-277648-9kxwkcbl	219	14	CD8	CD8	NNP
cord-277648-9kxwkcbl	219	15	+	+	CC
cord-277648-9kxwkcbl	219	16	effector	effector	NN
cord-277648-9kxwkcbl	219	17	,	,	,
cord-277648-9kxwkcbl	219	18	and	and	CC
cord-277648-9kxwkcbl	219	19	γδ	γδ	IN
cord-277648-9kxwkcbl	219	20	T	t	NN
cord-277648-9kxwkcbl	219	21	cells	cell	NNS
cord-277648-9kxwkcbl	219	22	.	.	.
cord-277648-9kxwkcbl	220	1	For	for	IN
cord-277648-9kxwkcbl	220	2	other	other	JJ
cord-277648-9kxwkcbl	220	3	cell	cell	NN
cord-277648-9kxwkcbl	220	4	types	type	NNS
cord-277648-9kxwkcbl	220	5	including	include	VBG
cord-277648-9kxwkcbl	220	6	MPs	mp	NNS
cord-277648-9kxwkcbl	220	7	/	/	SYM
cord-277648-9kxwkcbl	220	8	monocytes	monocyte	NNS
cord-277648-9kxwkcbl	220	9	,	,	,
cord-277648-9kxwkcbl	220	10	NK	NK	NNP
cord-277648-9kxwkcbl	220	11	and	and	CC
cord-277648-9kxwkcbl	220	12	CD8	CD8	NNP
cord-277648-9kxwkcbl	220	13	+	+	CC
cord-277648-9kxwkcbl	220	14	effector	effector	VB
cord-277648-9kxwkcbl	220	15	T	t	NN
cord-277648-9kxwkcbl	220	16	cells	cell	NNS
cord-277648-9kxwkcbl	220	17	,	,	,
cord-277648-9kxwkcbl	220	18	the	the	DT
cord-277648-9kxwkcbl	220	19	type	type	NN
cord-277648-9kxwkcbl	220	20	II	II	NNP
cord-277648-9kxwkcbl	220	21	interferon	interferon	NN
cord-277648-9kxwkcbl	220	22	response	response	NN
cord-277648-9kxwkcbl	220	23	appears	appear	VBZ
cord-277648-9kxwkcbl	220	24	to	to	TO
cord-277648-9kxwkcbl	220	25	be	be	VB
cord-277648-9kxwkcbl	220	26	increased	increase	VBN
cord-277648-9kxwkcbl	220	27	in	in	IN
cord-277648-9kxwkcbl	220	28	cells	cell	NNS
cord-277648-9kxwkcbl	220	29	of	of	IN
cord-277648-9kxwkcbl	220	30	the	the	DT
cord-277648-9kxwkcbl	220	31	lung	lung	NN
cord-277648-9kxwkcbl	220	32	but	but	CC
cord-277648-9kxwkcbl	220	33	decreased	decrease	VBD
cord-277648-9kxwkcbl	220	34	in	in	IN
cord-277648-9kxwkcbl	220	35	the	the	DT
cord-277648-9kxwkcbl	220	36	blood	blood	NN
cord-277648-9kxwkcbl	220	37	.	.	.
cord-277648-9kxwkcbl	221	1	Moreover	moreover	RB
cord-277648-9kxwkcbl	221	2	,	,	,
cord-277648-9kxwkcbl	221	3	our	-PRON-	PRP$
cord-277648-9kxwkcbl	221	4	analysis	analysis	NN
cord-277648-9kxwkcbl	221	5	identifies	identify	VBZ
cord-277648-9kxwkcbl	221	6	divergent	divergent	JJ
cord-277648-9kxwkcbl	221	7	severity	severity	NN
cord-277648-9kxwkcbl	221	8	-	-	HYPH
cord-277648-9kxwkcbl	221	9	specific	specific	JJ
cord-277648-9kxwkcbl	221	10	responses	response	NNS
cord-277648-9kxwkcbl	221	11	in	in	IN
cord-277648-9kxwkcbl	221	12	the	the	DT
cord-277648-9kxwkcbl	221	13	BALF	BALF	NNP
cord-277648-9kxwkcbl	221	14	and	and	CC
cord-277648-9kxwkcbl	221	15	blood	blood	NN
cord-277648-9kxwkcbl	221	16	in	in	IN
cord-277648-9kxwkcbl	221	17	terms	term	NNS
cord-277648-9kxwkcbl	221	18	of	of	IN
cord-277648-9kxwkcbl	221	19	the	the	DT
cord-277648-9kxwkcbl	221	20	TNF	TNF	NNP
cord-277648-9kxwkcbl	221	21	-	-	HYPH
cord-277648-9kxwkcbl	221	22	α	α	NNP
cord-277648-9kxwkcbl	221	23	signaling	signal	VBG
cord-277648-9kxwkcbl	221	24	via	via	IN
cord-277648-9kxwkcbl	221	25	NF	nf	NN
cord-277648-9kxwkcbl	221	26	-	-	HYPH
cord-277648-9kxwkcbl	221	27	κB	κB	NNP
cord-277648-9kxwkcbl	221	28	pathway	pathway	NN
cord-277648-9kxwkcbl	221	29	for	for	IN
cord-277648-9kxwkcbl	221	30	nearly	nearly	RB
cord-277648-9kxwkcbl	221	31	all	all	DT
cord-277648-9kxwkcbl	221	32	cell	cell	NN
cord-277648-9kxwkcbl	221	33	types	type	NNS
cord-277648-9kxwkcbl	221	34	.	.	.
cord-277648-9kxwkcbl	222	1	Notably	notably	RB
cord-277648-9kxwkcbl	222	2	,	,	,
cord-277648-9kxwkcbl	222	3	the	the	DT
cord-277648-9kxwkcbl	222	4	concerted	concerted	JJ
cord-277648-9kxwkcbl	222	5	TNF	TNF	NNP
cord-277648-9kxwkcbl	222	6	-	-	HYPH
cord-277648-9kxwkcbl	222	7	α	α	NNP
cord-277648-9kxwkcbl	222	8	/	/	SYM
cord-277648-9kxwkcbl	222	9	NF	nf	NN
cord-277648-9kxwkcbl	222	10	-	-	HYPH
cord-277648-9kxwkcbl	222	11	κB	κB	NNP
cord-277648-9kxwkcbl	222	12	pathway	pathway	NN
cord-277648-9kxwkcbl	222	13	enrichment	enrichment	NN
cord-277648-9kxwkcbl	222	14	across	across	IN
cord-277648-9kxwkcbl	222	15	BALF	BALF	NNP
cord-277648-9kxwkcbl	222	16	cell	cell	NN
cord-277648-9kxwkcbl	222	17	types	type	NNS
cord-277648-9kxwkcbl	222	18	is	be	VBZ
cord-277648-9kxwkcbl	222	19	indicative	indicative	JJ
cord-277648-9kxwkcbl	222	20	of	of	IN
cord-277648-9kxwkcbl	222	21	a	a	DT
cord-277648-9kxwkcbl	222	22	strong	strong	JJ
cord-277648-9kxwkcbl	222	23	upregulation	upregulation	NN
cord-277648-9kxwkcbl	222	24	of	of	IN
cord-277648-9kxwkcbl	222	25	TNFAIP3	TNFAIP3	NNS
cord-277648-9kxwkcbl	222	26	and	and	CC
cord-277648-9kxwkcbl	222	27	NFKBIA	NFKBIA	NNP
cord-277648-9kxwkcbl	222	28	.	.	.
cord-277648-9kxwkcbl	223	1	Conversely	conversely	RB
cord-277648-9kxwkcbl	223	2	,	,	,
cord-277648-9kxwkcbl	223	3	the	the	DT
cord-277648-9kxwkcbl	223	4	depleted	deplete	VBN
cord-277648-9kxwkcbl	223	5	pathway	pathway	NN
cord-277648-9kxwkcbl	223	6	across	across	IN
cord-277648-9kxwkcbl	223	7	PBMC	PBMC	NNP
cord-277648-9kxwkcbl	223	8	cell	cell	NN
cord-277648-9kxwkcbl	223	9	types	type	NNS
cord-277648-9kxwkcbl	223	10	corresponds	correspond	VBZ
cord-277648-9kxwkcbl	223	11	to	to	IN
cord-277648-9kxwkcbl	223	12	TNFAIP3	TNFAIP3	NNP
cord-277648-9kxwkcbl	223	13	and	and	CC
cord-277648-9kxwkcbl	223	14	NFKBIA	NFKBIA	NNP
cord-277648-9kxwkcbl	223	15	downregulation	downregulation	NN
cord-277648-9kxwkcbl	223	16	.	.	.
cord-277648-9kxwkcbl	224	1	The	the	DT
cord-277648-9kxwkcbl	224	2	A20	A20	NNP
cord-277648-9kxwkcbl	224	3	protein	protein	NN
cord-277648-9kxwkcbl	224	4	encoded	encode	VBN
cord-277648-9kxwkcbl	224	5	by	by	IN
cord-277648-9kxwkcbl	224	6	TNFAIP3	TNFAIP3	NNP
cord-277648-9kxwkcbl	224	7	is	be	VBZ
cord-277648-9kxwkcbl	224	8	an	an	DT
cord-277648-9kxwkcbl	224	9	NF	nf	NN
cord-277648-9kxwkcbl	224	10	-	-	HYPH
cord-277648-9kxwkcbl	224	11	κB	κb	CD
cord-277648-9kxwkcbl	224	12	inhibitor	inhibitor	NN
cord-277648-9kxwkcbl	224	13	that	that	WDT
cord-277648-9kxwkcbl	224	14	functions	function	VBZ
cord-277648-9kxwkcbl	224	15	as	as	IN
cord-277648-9kxwkcbl	224	16	a	a	DT
cord-277648-9kxwkcbl	224	17	"	"	``
cord-277648-9kxwkcbl	224	18	brake	brake	NN
cord-277648-9kxwkcbl	224	19	"	"	''
cord-277648-9kxwkcbl	224	20	on	on	IN
cord-277648-9kxwkcbl	224	21	antiviral	antiviral	JJ
cord-277648-9kxwkcbl	224	22	signaling	signaling	NN
cord-277648-9kxwkcbl	224	23	and	and	CC
cord-277648-9kxwkcbl	224	24	inflammatory	inflammatory	JJ
cord-277648-9kxwkcbl	224	25	responses	response	NNS
cord-277648-9kxwkcbl	224	26	[	[	-LRB-
cord-277648-9kxwkcbl	224	27	56	56	CD
cord-277648-9kxwkcbl	224	28	,	,	,
cord-277648-9kxwkcbl	224	29	57	57	CD
cord-277648-9kxwkcbl	224	30	,	,	,
cord-277648-9kxwkcbl	224	31	58	58	CD
cord-277648-9kxwkcbl	224	32	,	,	,
cord-277648-9kxwkcbl	224	33	59	59	CD
cord-277648-9kxwkcbl	224	34	]	]	-RRB-
cord-277648-9kxwkcbl	224	35	whose	whose	WP$
cord-277648-9kxwkcbl	224	36	deletion	deletion	NN
cord-277648-9kxwkcbl	224	37	in	in	IN
cord-277648-9kxwkcbl	224	38	mouse	mouse	NN
cord-277648-9kxwkcbl	224	39	models	model	NNS
cord-277648-9kxwkcbl	224	40	improved	improve	VBD
cord-277648-9kxwkcbl	224	41	survival	survival	NN
cord-277648-9kxwkcbl	224	42	during	during	IN
cord-277648-9kxwkcbl	224	43	influenza	influenza	NN
cord-277648-9kxwkcbl	224	44	infection	infection	NN
cord-277648-9kxwkcbl	224	45	[	[	-LRB-
cord-277648-9kxwkcbl	224	46	59	59	CD
cord-277648-9kxwkcbl	224	47	]	]	-RRB-
cord-277648-9kxwkcbl	224	48	.	.	.
cord-277648-9kxwkcbl	225	1	TFNAIP3	TFNAIP3	NNP
cord-277648-9kxwkcbl	225	2	differential	differential	JJ
cord-277648-9kxwkcbl	225	3	expression	expression	NN
cord-277648-9kxwkcbl	225	4	was	be	VBD
cord-277648-9kxwkcbl	225	5	largely	largely	RB
cord-277648-9kxwkcbl	225	6	co	co	JJ
cord-277648-9kxwkcbl	225	7	-	-	JJ
cord-277648-9kxwkcbl	225	8	directional	directional	JJ
cord-277648-9kxwkcbl	225	9	with	with	IN
cord-277648-9kxwkcbl	225	10	NFKBIA	NFKBIA	NNP
cord-277648-9kxwkcbl	225	11	(	(	-LRB-
cord-277648-9kxwkcbl	225	12	coding	code	VBG
cord-277648-9kxwkcbl	225	13	for	for	IN
cord-277648-9kxwkcbl	225	14	IκBα	IκBα	NNP
cord-277648-9kxwkcbl	225	15	)	)	-RRB-
cord-277648-9kxwkcbl	225	16	,	,	,
cord-277648-9kxwkcbl	225	17	a	a	DT
cord-277648-9kxwkcbl	225	18	gene	gene	NN
cord-277648-9kxwkcbl	225	19	whose	whose	WP$
cord-277648-9kxwkcbl	225	20	upregulation	upregulation	NN
cord-277648-9kxwkcbl	225	21	is	be	VBZ
cord-277648-9kxwkcbl	225	22	a	a	DT
cord-277648-9kxwkcbl	225	23	key	key	JJ
cord-277648-9kxwkcbl	225	24	feature	feature	NN
cord-277648-9kxwkcbl	225	25	of	of	IN
cord-277648-9kxwkcbl	225	26	the	the	DT
cord-277648-9kxwkcbl	225	27	human	human	JJ
cord-277648-9kxwkcbl	225	28	blood	blood	NN
cord-277648-9kxwkcbl	225	29	response	response	NN
cord-277648-9kxwkcbl	225	30	to	to	IN
cord-277648-9kxwkcbl	225	31	SARS	SARS	NNP
cord-277648-9kxwkcbl	225	32	-	-	HYPH
cord-277648-9kxwkcbl	225	33	CoV	CoV	NNP
cord-277648-9kxwkcbl	225	34	as	as	RB
cord-277648-9kxwkcbl	225	35	well	well	RB
cord-277648-9kxwkcbl	225	36	as	as	IN
cord-277648-9kxwkcbl	225	37	the	the	DT
cord-277648-9kxwkcbl	225	38	lung	lung	NN
cord-277648-9kxwkcbl	225	39	response	response	NN
cord-277648-9kxwkcbl	225	40	to	to	IN
cord-277648-9kxwkcbl	225	41	SARS	SARS	NNP
cord-277648-9kxwkcbl	225	42	-	-	HYPH
cord-277648-9kxwkcbl	225	43	CoV	CoV	NNP
cord-277648-9kxwkcbl	225	44	and	and	CC
cord-277648-9kxwkcbl	225	45	MERS	MERS	NNP
cord-277648-9kxwkcbl	225	46	-	-	HYPH
cord-277648-9kxwkcbl	225	47	CoV	cov	NN
cord-277648-9kxwkcbl	225	48	infection	infection	NN
cord-277648-9kxwkcbl	225	49	[	[	-LRB-
cord-277648-9kxwkcbl	225	50	60	60	CD
cord-277648-9kxwkcbl	225	51	]	]	-RRB-
cord-277648-9kxwkcbl	225	52	.	.	.
cord-277648-9kxwkcbl	226	1	Our	-PRON-	PRP$
cord-277648-9kxwkcbl	226	2	results	result	NNS
cord-277648-9kxwkcbl	226	3	suggest	suggest	VBP
cord-277648-9kxwkcbl	226	4	that	that	IN
cord-277648-9kxwkcbl	226	5	the	the	DT
cord-277648-9kxwkcbl	226	6	A20	A20	NNP
cord-277648-9kxwkcbl	226	7	/	/	SYM
cord-277648-9kxwkcbl	226	8	IκBα	IκBα	NNP
cord-277648-9kxwkcbl	226	9	axis	axis	NN
cord-277648-9kxwkcbl	226	10	likely	likely	RB
cord-277648-9kxwkcbl	226	11	plays	play	VBZ
cord-277648-9kxwkcbl	226	12	a	a	DT
cord-277648-9kxwkcbl	226	13	role	role	NN
cord-277648-9kxwkcbl	226	14	in	in	IN
cord-277648-9kxwkcbl	226	15	SARS	SARS	NNP
cord-277648-9kxwkcbl	226	16	-	-	HYPH
cord-277648-9kxwkcbl	226	17	CoV-2	CoV-2	NNP
cord-277648-9kxwkcbl	226	18	infection	infection	NN
cord-277648-9kxwkcbl	226	19	as	as	RB
cord-277648-9kxwkcbl	226	20	well	well	RB
cord-277648-9kxwkcbl	226	21	,	,	,
cord-277648-9kxwkcbl	226	22	with	with	IN
cord-277648-9kxwkcbl	226	23	TNFAIP3	TNFAIP3	NNS
cord-277648-9kxwkcbl	226	24	inhibiting	inhibit	VBG
cord-277648-9kxwkcbl	226	25	NF	nf	NN
cord-277648-9kxwkcbl	226	26	-	-	HYPH
cord-277648-9kxwkcbl	226	27	κB	κB	NNP
cord-277648-9kxwkcbl	226	28	-	-	HYPH
cord-277648-9kxwkcbl	226	29	mediated	mediate	VBN
cord-277648-9kxwkcbl	226	30	antiviral	antiviral	JJ
cord-277648-9kxwkcbl	226	31	responses	response	NNS
cord-277648-9kxwkcbl	226	32	during	during	IN
cord-277648-9kxwkcbl	226	33	severe	severe	JJ
cord-277648-9kxwkcbl	226	34	disease	disease	NN
cord-277648-9kxwkcbl	226	35	at	at	IN
cord-277648-9kxwkcbl	226	36	the	the	DT
cord-277648-9kxwkcbl	226	37	site	site	NN
cord-277648-9kxwkcbl	226	38	of	of	IN
cord-277648-9kxwkcbl	226	39	local	local	JJ
cord-277648-9kxwkcbl	226	40	infection	infection	NN
cord-277648-9kxwkcbl	226	41	yet	yet	CC
cord-277648-9kxwkcbl	226	42	promoting	promote	VBG
cord-277648-9kxwkcbl	226	43	a	a	DT
cord-277648-9kxwkcbl	226	44	systemic	systemic	JJ
cord-277648-9kxwkcbl	226	45	inflammatory	inflammatory	JJ
cord-277648-9kxwkcbl	226	46	response	response	NN
cord-277648-9kxwkcbl	226	47	through	through	IN
cord-277648-9kxwkcbl	226	48	its	-PRON-	PRP$
cord-277648-9kxwkcbl	226	49	absence	absence	NN
cord-277648-9kxwkcbl	226	50	during	during	IN
cord-277648-9kxwkcbl	226	51	ARDS	ARDS	NNP
cord-277648-9kxwkcbl	226	52	in	in	IN
cord-277648-9kxwkcbl	226	53	the	the	DT
cord-277648-9kxwkcbl	226	54	periphery	periphery	NN
cord-277648-9kxwkcbl	226	55	.	.	.
cord-277648-9kxwkcbl	227	1	We	-PRON-	PRP
cord-277648-9kxwkcbl	227	2	note	note	VBP
cord-277648-9kxwkcbl	227	3	in	in	IN
cord-277648-9kxwkcbl	227	4	this	this	DT
cord-277648-9kxwkcbl	227	5	compartmental	compartmental	JJ
cord-277648-9kxwkcbl	227	6	comparison	comparison	NN
cord-277648-9kxwkcbl	227	7	that	that	WDT
cord-277648-9kxwkcbl	227	8	the	the	DT
cord-277648-9kxwkcbl	227	9	BALF	BALF	NNP
cord-277648-9kxwkcbl	227	10	and	and	CC
cord-277648-9kxwkcbl	227	11	PBMC	PBMC	NNP
cord-277648-9kxwkcbl	227	12	clinical	clinical	JJ
cord-277648-9kxwkcbl	227	13	stratifications	stratification	NNS
cord-277648-9kxwkcbl	227	14	represent	represent	VBP
cord-277648-9kxwkcbl	227	15	different	different	JJ
cord-277648-9kxwkcbl	227	16	parts	part	NNS
cord-277648-9kxwkcbl	227	17	of	of	IN
cord-277648-9kxwkcbl	227	18	the	the	DT
cord-277648-9kxwkcbl	227	19	disease	disease	NN
cord-277648-9kxwkcbl	227	20	severity	severity	NN
cord-277648-9kxwkcbl	227	21	spectrum	spectrum	NN
cord-277648-9kxwkcbl	227	22	.	.	.
cord-277648-9kxwkcbl	228	1	Therefore	therefore	RB
cord-277648-9kxwkcbl	228	2	,	,	,
cord-277648-9kxwkcbl	228	3	we	-PRON-	PRP
cord-277648-9kxwkcbl	228	4	interpret	interpret	VBP
cord-277648-9kxwkcbl	228	5	differences	difference	NNS
cord-277648-9kxwkcbl	228	6	in	in	IN
cord-277648-9kxwkcbl	228	7	compartmental	compartmental	JJ
cord-277648-9kxwkcbl	228	8	responses	response	NNS
cord-277648-9kxwkcbl	228	9	with	with	IN
cord-277648-9kxwkcbl	228	10	respect	respect	NN
cord-277648-9kxwkcbl	228	11	to	to	IN
cord-277648-9kxwkcbl	228	12	relative	relative	JJ
cord-277648-9kxwkcbl	228	13	levels	level	NNS
cord-277648-9kxwkcbl	228	14	of	of	IN
cord-277648-9kxwkcbl	228	15	clinical	clinical	JJ
cord-277648-9kxwkcbl	228	16	severity	severity	NN
cord-277648-9kxwkcbl	228	17	rather	rather	RB
cord-277648-9kxwkcbl	228	18	than	than	IN
cord-277648-9kxwkcbl	228	19	absolute	absolute	JJ
cord-277648-9kxwkcbl	228	20	severity	severity	NN
cord-277648-9kxwkcbl	228	21	stages	stage	NNS
cord-277648-9kxwkcbl	228	22	.	.	.
cord-277648-9kxwkcbl	229	1	Taken	take	VBN
cord-277648-9kxwkcbl	229	2	together	together	RB
cord-277648-9kxwkcbl	229	3	,	,	,
cord-277648-9kxwkcbl	229	4	our	-PRON-	PRP$
cord-277648-9kxwkcbl	229	5	data	datum	NNS
cord-277648-9kxwkcbl	229	6	suggest	suggest	VBP
cord-277648-9kxwkcbl	229	7	that	that	IN
cord-277648-9kxwkcbl	229	8	transcriptional	transcriptional	JJ
cord-277648-9kxwkcbl	229	9	programs	program	NNS
cord-277648-9kxwkcbl	229	10	are	be	VBP
cord-277648-9kxwkcbl	229	11	differentially	differentially	RB
cord-277648-9kxwkcbl	229	12	induced	induce	VBN
cord-277648-9kxwkcbl	229	13	with	with	IN
cord-277648-9kxwkcbl	229	14	increasing	increase	VBG
cord-277648-9kxwkcbl	229	15	COVID-19	covid-19	JJ
cord-277648-9kxwkcbl	229	16	severity	severity	NN
cord-277648-9kxwkcbl	229	17	,	,	,
cord-277648-9kxwkcbl	229	18	while	while	IN
cord-277648-9kxwkcbl	229	19	the	the	DT
cord-277648-9kxwkcbl	229	20	specific	specific	JJ
cord-277648-9kxwkcbl	229	21	responses	response	NNS
cord-277648-9kxwkcbl	229	22	are	be	VBP
cord-277648-9kxwkcbl	229	23	nuanced	nuanced	JJ
cord-277648-9kxwkcbl	229	24	according	accord	VBG
cord-277648-9kxwkcbl	229	25	to	to	IN
cord-277648-9kxwkcbl	229	26	cell	cell	NN
cord-277648-9kxwkcbl	229	27	type	type	NN
cord-277648-9kxwkcbl	229	28	and	and	CC
cord-277648-9kxwkcbl	229	29	local	local	JJ
cord-277648-9kxwkcbl	229	30	versus	versus	IN
cord-277648-9kxwkcbl	229	31	systemic	systemic	JJ
cord-277648-9kxwkcbl	229	32	immune	immune	JJ
cord-277648-9kxwkcbl	229	33	environment	environment	NN
cord-277648-9kxwkcbl	229	34	.	.	.
cord-277648-9kxwkcbl	230	1	In	in	IN
cord-277648-9kxwkcbl	230	2	epithelial	epithelial	JJ
cord-277648-9kxwkcbl	230	3	cells	cell	NNS
cord-277648-9kxwkcbl	230	4	of	of	IN
cord-277648-9kxwkcbl	230	5	the	the	DT
cord-277648-9kxwkcbl	230	6	BALF	BALF	NNP
cord-277648-9kxwkcbl	230	7	,	,	,
cord-277648-9kxwkcbl	230	8	we	-PRON-	PRP
cord-277648-9kxwkcbl	230	9	detected	detect	VBD
cord-277648-9kxwkcbl	230	10	the	the	DT
cord-277648-9kxwkcbl	230	11	surprising	surprising	JJ
cord-277648-9kxwkcbl	230	12	upregulation	upregulation	NN
cord-277648-9kxwkcbl	230	13	of	of	IN
cord-277648-9kxwkcbl	230	14	FOS	FOS	NNP
cord-277648-9kxwkcbl	230	15	and	and	CC
cord-277648-9kxwkcbl	230	16	JUN	JUN	NNP
cord-277648-9kxwkcbl	230	17	,	,	,
cord-277648-9kxwkcbl	230	18	along	along	IN
cord-277648-9kxwkcbl	230	19	with	with	IN
cord-277648-9kxwkcbl	230	20	the	the	DT
cord-277648-9kxwkcbl	230	21	downregulation	downregulation	NN
cord-277648-9kxwkcbl	230	22	of	of	IN
cord-277648-9kxwkcbl	230	23	C2orf40	C2orf40	NNP
cord-277648-9kxwkcbl	230	24	in	in	IN
cord-277648-9kxwkcbl	230	25	severe	severe	JJ
cord-277648-9kxwkcbl	230	26	compared	compare	VBN
cord-277648-9kxwkcbl	230	27	to	to	IN
cord-277648-9kxwkcbl	230	28	moderate	moderate	JJ
cord-277648-9kxwkcbl	230	29	donors	donor	NNS
cord-277648-9kxwkcbl	230	30	.	.	.
cord-277648-9kxwkcbl	231	1	Due	due	IN
cord-277648-9kxwkcbl	231	2	to	to	IN
cord-277648-9kxwkcbl	231	3	the	the	DT
cord-277648-9kxwkcbl	231	4	involvement	involvement	NN
cord-277648-9kxwkcbl	231	5	of	of	IN
cord-277648-9kxwkcbl	231	6	these	these	DT
cord-277648-9kxwkcbl	231	7	genes	gene	NNS
cord-277648-9kxwkcbl	231	8	in	in	IN
cord-277648-9kxwkcbl	231	9	oncogenic	oncogenic	JJ
cord-277648-9kxwkcbl	231	10	programs	program	NNS
cord-277648-9kxwkcbl	231	11	,	,	,
cord-277648-9kxwkcbl	231	12	we	-PRON-	PRP
cord-277648-9kxwkcbl	231	13	further	further	RB
cord-277648-9kxwkcbl	231	14	investigated	investigate	VBD
cord-277648-9kxwkcbl	231	15	pathway	pathway	NN
cord-277648-9kxwkcbl	231	16	-	-	HYPH
cord-277648-9kxwkcbl	231	17	level	level	NN
cord-277648-9kxwkcbl	231	18	alterations	alteration	NNS
cord-277648-9kxwkcbl	231	19	in	in	IN
cord-277648-9kxwkcbl	231	20	epithelial	epithelial	JJ
cord-277648-9kxwkcbl	231	21	cells	cell	NNS
cord-277648-9kxwkcbl	231	22	and	and	CC
cord-277648-9kxwkcbl	231	23	detected	detect	VBD
cord-277648-9kxwkcbl	231	24	the	the	DT
cord-277648-9kxwkcbl	231	25	enrichment	enrichment	NN
cord-277648-9kxwkcbl	231	26	of	of	IN
cord-277648-9kxwkcbl	231	27	epithelial	epithelial	NN
cord-277648-9kxwkcbl	231	28	-	-	HYPH
cord-277648-9kxwkcbl	231	29	to	to	IN
cord-277648-9kxwkcbl	231	30	-	-	HYPH
cord-277648-9kxwkcbl	231	31	mesenchymal	mesenchymal	JJ
cord-277648-9kxwkcbl	231	32	transition	transition	NN
cord-277648-9kxwkcbl	231	33	,	,	,
cord-277648-9kxwkcbl	231	34	K	K	NNP
cord-277648-9kxwkcbl	231	35	-	-	HYPH
cord-277648-9kxwkcbl	231	36	Ras	Ras	NNP
cord-277648-9kxwkcbl	231	37	,	,	,
cord-277648-9kxwkcbl	231	38	PI3K	PI3K	NNP
cord-277648-9kxwkcbl	231	39	/	/	SYM
cord-277648-9kxwkcbl	231	40	AKT	akt	NN
cord-277648-9kxwkcbl	231	41	and	and	CC
cord-277648-9kxwkcbl	231	42	p53	p53	NN
cord-277648-9kxwkcbl	231	43	pathways	pathway	NNS
cord-277648-9kxwkcbl	231	44	.	.	.
cord-277648-9kxwkcbl	232	1	We	-PRON-	PRP
cord-277648-9kxwkcbl	232	2	note	note	VBP
cord-277648-9kxwkcbl	232	3	that	that	IN
cord-277648-9kxwkcbl	232	4	a	a	DT
cord-277648-9kxwkcbl	232	5	separate	separate	JJ
cord-277648-9kxwkcbl	232	6	analysis	analysis	NN
cord-277648-9kxwkcbl	232	7	of	of	IN
cord-277648-9kxwkcbl	232	8	epithelial	epithelial	JJ
cord-277648-9kxwkcbl	232	9	cells	cell	NNS
cord-277648-9kxwkcbl	232	10	from	from	IN
cord-277648-9kxwkcbl	232	11	the	the	DT
cord-277648-9kxwkcbl	232	12	same	same	JJ
cord-277648-9kxwkcbl	232	13	BALF	BALF	NNP
cord-277648-9kxwkcbl	232	14	dataset	dataset	NN
cord-277648-9kxwkcbl	232	15	failed	fail	VBD
cord-277648-9kxwkcbl	232	16	to	to	TO
cord-277648-9kxwkcbl	232	17	detect	detect	VB
cord-277648-9kxwkcbl	232	18	differential	differential	JJ
cord-277648-9kxwkcbl	232	19	enrichment	enrichment	NN
cord-277648-9kxwkcbl	232	20	of	of	IN
cord-277648-9kxwkcbl	232	21	these	these	DT
cord-277648-9kxwkcbl	232	22	pathways	pathway	NNS
cord-277648-9kxwkcbl	232	23	through	through	IN
cord-277648-9kxwkcbl	232	24	GSEA	GSEA	NNP
cord-277648-9kxwkcbl	232	25	when	when	WRB
cord-277648-9kxwkcbl	232	26	comparing	compare	VBG
cord-277648-9kxwkcbl	232	27	control	control	NN
cord-277648-9kxwkcbl	232	28	samples	sample	NNS
cord-277648-9kxwkcbl	232	29	to	to	IN
cord-277648-9kxwkcbl	232	30	pooled	pool	VBN
cord-277648-9kxwkcbl	232	31	moderate	moderate	JJ
cord-277648-9kxwkcbl	232	32	and	and	CC
cord-277648-9kxwkcbl	232	33	severe	severe	JJ
cord-277648-9kxwkcbl	232	34	samples	sample	NNS
cord-277648-9kxwkcbl	232	35	[	[	-LRB-
cord-277648-9kxwkcbl	232	36	21	21	CD
cord-277648-9kxwkcbl	232	37	,	,	,
cord-277648-9kxwkcbl	232	38	53	53	CD
cord-277648-9kxwkcbl	232	39	]	]	-RRB-
cord-277648-9kxwkcbl	232	40	,	,	,
cord-277648-9kxwkcbl	232	41	likely	likely	RB
cord-277648-9kxwkcbl	232	42	as	as	IN
cord-277648-9kxwkcbl	232	43	a	a	DT
cord-277648-9kxwkcbl	232	44	result	result	NN
cord-277648-9kxwkcbl	232	45	of	of	IN
cord-277648-9kxwkcbl	232	46	this	this	DT
cord-277648-9kxwkcbl	232	47	pooling	pooling	NN
cord-277648-9kxwkcbl	232	48	and	and	CC
cord-277648-9kxwkcbl	232	49	using	use	VBG
cord-277648-9kxwkcbl	232	50	a	a	DT
cord-277648-9kxwkcbl	232	51	much	much	RB
cord-277648-9kxwkcbl	232	52	shorter	short	JJR
cord-277648-9kxwkcbl	232	53	list	list	NN
cord-277648-9kxwkcbl	232	54	of	of	IN
cord-277648-9kxwkcbl	232	55	statistically	statistically	RB
cord-277648-9kxwkcbl	232	56	tested	test	VBN
cord-277648-9kxwkcbl	232	57	genes	gene	NNS
cord-277648-9kxwkcbl	232	58	(	(	-LRB-
cord-277648-9kxwkcbl	232	59	a	a	DT
cord-277648-9kxwkcbl	232	60	single	single	JJ
cord-277648-9kxwkcbl	232	61	set	set	NN
cord-277648-9kxwkcbl	232	62	of	of	IN
cord-277648-9kxwkcbl	232	63	118	118	CD
cord-277648-9kxwkcbl	232	64	genes	gene	NNS
cord-277648-9kxwkcbl	232	65	common	common	JJ
cord-277648-9kxwkcbl	232	66	to	to	IN
cord-277648-9kxwkcbl	232	67	all	all	DT
cord-277648-9kxwkcbl	232	68	epithelial	epithelial	JJ
cord-277648-9kxwkcbl	232	69	cells	cell	NNS
cord-277648-9kxwkcbl	232	70	compared	compare	VBN
cord-277648-9kxwkcbl	232	71	to	to	IN
cord-277648-9kxwkcbl	232	72	sets	set	NNS
cord-277648-9kxwkcbl	232	73	of	of	IN
cord-277648-9kxwkcbl	232	74	1,561	1,561	CD
cord-277648-9kxwkcbl	232	75	genes	gene	NNS
cord-277648-9kxwkcbl	232	76	for	for	IN
cord-277648-9kxwkcbl	232	77	ciliated	ciliated	JJ
cord-277648-9kxwkcbl	232	78	cells	cell	NNS
cord-277648-9kxwkcbl	232	79	and	and	CC
cord-277648-9kxwkcbl	232	80	1,092	1,092	CD
cord-277648-9kxwkcbl	232	81	genes	gene	NNS
cord-277648-9kxwkcbl	232	82	for	for	IN
cord-277648-9kxwkcbl	232	83	club	club	NN
cord-277648-9kxwkcbl	232	84	cells	cell	NNS
cord-277648-9kxwkcbl	232	85	)	)	-RRB-
cord-277648-9kxwkcbl	232	86	.	.	.
cord-277648-9kxwkcbl	233	1	Our	-PRON-	PRP$
cord-277648-9kxwkcbl	233	2	results	result	NNS
cord-277648-9kxwkcbl	233	3	may	may	MD
cord-277648-9kxwkcbl	233	4	be	be	VB
cord-277648-9kxwkcbl	233	5	cautiously	cautiously	RB
cord-277648-9kxwkcbl	233	6	interpreted	interpret	VBN
cord-277648-9kxwkcbl	233	7	as	as	IN
cord-277648-9kxwkcbl	233	8	providing	provide	VBG
cord-277648-9kxwkcbl	233	9	evidence	evidence	NN
cord-277648-9kxwkcbl	233	10	for	for	IN
cord-277648-9kxwkcbl	233	11	the	the	DT
cord-277648-9kxwkcbl	233	12	molecular	molecular	JJ
cord-277648-9kxwkcbl	233	13	underpinnings	underpinning	NNS
cord-277648-9kxwkcbl	233	14	of	of	IN
cord-277648-9kxwkcbl	233	15	the	the	DT
cord-277648-9kxwkcbl	233	16	morphological	morphological	JJ
cord-277648-9kxwkcbl	233	17	changes	change	NNS
cord-277648-9kxwkcbl	233	18	known	know	VBN
cord-277648-9kxwkcbl	233	19	to	to	TO
cord-277648-9kxwkcbl	233	20	occur	occur	VB
cord-277648-9kxwkcbl	233	21	in	in	IN
cord-277648-9kxwkcbl	233	22	the	the	DT
cord-277648-9kxwkcbl	233	23	severely	severely	RB
cord-277648-9kxwkcbl	233	24	damaged	damage	VBN
cord-277648-9kxwkcbl	233	25	lung	lung	NN
cord-277648-9kxwkcbl	233	26	epithelia	epithelium	NNS
cord-277648-9kxwkcbl	233	27	of	of	IN
cord-277648-9kxwkcbl	233	28	severe	severe	JJ
cord-277648-9kxwkcbl	233	29	COVID-19	covid-19	JJ
cord-277648-9kxwkcbl	233	30	patients	patient	NNS
cord-277648-9kxwkcbl	233	31	,	,	,
cord-277648-9kxwkcbl	233	32	previously	previously	RB
cord-277648-9kxwkcbl	233	33	described	describe	VBN
cord-277648-9kxwkcbl	233	34	as	as	IN
cord-277648-9kxwkcbl	233	35	cellular	cellular	JJ
cord-277648-9kxwkcbl	233	36	proliferation	proliferation	NN
cord-277648-9kxwkcbl	233	37	resembling	resemble	VBG
cord-277648-9kxwkcbl	233	38	atypical	atypical	JJ
cord-277648-9kxwkcbl	233	39	adenomatous	adenomatous	JJ
cord-277648-9kxwkcbl	233	40	hyperplasia	hyperplasia	NN
cord-277648-9kxwkcbl	233	41	,	,	,
cord-277648-9kxwkcbl	233	42	in	in	IN
cord-277648-9kxwkcbl	233	43	situ	situ	JJ
cord-277648-9kxwkcbl	233	44	adenocarcinoma	adenocarcinoma	NN
cord-277648-9kxwkcbl	233	45	,	,	,
cord-277648-9kxwkcbl	233	46	or	or	CC
cord-277648-9kxwkcbl	233	47	even	even	RB
cord-277648-9kxwkcbl	233	48	invasive	invasive	JJ
cord-277648-9kxwkcbl	233	49	adenocarcinoma	adenocarcinoma	NN
cord-277648-9kxwkcbl	233	50	[	[	-LRB-
cord-277648-9kxwkcbl	233	51	15	15	CD
cord-277648-9kxwkcbl	233	52	]	]	-RRB-
cord-277648-9kxwkcbl	233	53	.	.	.
cord-277648-9kxwkcbl	234	1	Following	follow	VBG
cord-277648-9kxwkcbl	234	2	the	the	DT
cord-277648-9kxwkcbl	234	3	observation	observation	NN
cord-277648-9kxwkcbl	234	4	of	of	IN
cord-277648-9kxwkcbl	234	5	pathways	pathway	NNS
cord-277648-9kxwkcbl	234	6	enriched	enrich	VBN
cord-277648-9kxwkcbl	234	7	in	in	IN
cord-277648-9kxwkcbl	234	8	the	the	DT
cord-277648-9kxwkcbl	234	9	epithelia	epithelium	NNS
cord-277648-9kxwkcbl	234	10	of	of	IN
cord-277648-9kxwkcbl	234	11	severe	severe	JJ
cord-277648-9kxwkcbl	234	12	COVID-19	covid-19	JJ
cord-277648-9kxwkcbl	234	13	patients	patient	NNS
cord-277648-9kxwkcbl	234	14	,	,	,
cord-277648-9kxwkcbl	234	15	we	-PRON-	PRP
cord-277648-9kxwkcbl	234	16	employed	employ	VBD
cord-277648-9kxwkcbl	234	17	ligand	ligand	NN
cord-277648-9kxwkcbl	234	18	-	-	HYPH
cord-277648-9kxwkcbl	234	19	receptor	receptor	NN
cord-277648-9kxwkcbl	234	20	network	network	NN
cord-277648-9kxwkcbl	234	21	analysis	analysis	NN
cord-277648-9kxwkcbl	234	22	to	to	TO
cord-277648-9kxwkcbl	234	23	nominate	nominate	VB
cord-277648-9kxwkcbl	234	24	potential	potential	JJ
cord-277648-9kxwkcbl	234	25	immune	immune	JJ
cord-277648-9kxwkcbl	234	26	-	-	HYPH
cord-277648-9kxwkcbl	234	27	epithelial	epithelial	JJ
cord-277648-9kxwkcbl	234	28	communication	communication	NN
cord-277648-9kxwkcbl	234	29	networks	network	NNS
cord-277648-9kxwkcbl	234	30	that	that	WDT
cord-277648-9kxwkcbl	234	31	may	may	MD
cord-277648-9kxwkcbl	234	32	explain	explain	VB
cord-277648-9kxwkcbl	234	33	transcriptional	transcriptional	JJ
cord-277648-9kxwkcbl	234	34	differences	difference	NNS
cord-277648-9kxwkcbl	234	35	between	between	IN
cord-277648-9kxwkcbl	234	36	severe	severe	JJ
cord-277648-9kxwkcbl	234	37	and	and	CC
cord-277648-9kxwkcbl	234	38	moderate	moderate	JJ
cord-277648-9kxwkcbl	234	39	disease	disease	NN
cord-277648-9kxwkcbl	234	40	courses	course	NNS
cord-277648-9kxwkcbl	234	41	.	.	.
cord-277648-9kxwkcbl	235	1	We	-PRON-	PRP
cord-277648-9kxwkcbl	235	2	identified	identify	VBD
cord-277648-9kxwkcbl	235	3	16	16	CD
cord-277648-9kxwkcbl	235	4	ligands	ligand	NNS
cord-277648-9kxwkcbl	235	5	implicated	implicate	VBN
cord-277648-9kxwkcbl	235	6	in	in	IN
cord-277648-9kxwkcbl	235	7	driving	drive	VBG
cord-277648-9kxwkcbl	235	8	the	the	DT
cord-277648-9kxwkcbl	235	9	differential	differential	JJ
cord-277648-9kxwkcbl	235	10	expression	expression	NN
cord-277648-9kxwkcbl	235	11	in	in	IN
cord-277648-9kxwkcbl	235	12	ciliated	ciliated	JJ
cord-277648-9kxwkcbl	235	13	and	and	CC
cord-277648-9kxwkcbl	235	14	club	club	NN
cord-277648-9kxwkcbl	235	15	cells	cell	NNS
cord-277648-9kxwkcbl	235	16	,	,	,
cord-277648-9kxwkcbl	235	17	of	of	IN
cord-277648-9kxwkcbl	235	18	which	which	WDT
cord-277648-9kxwkcbl	235	19	IL1B	il1b	NN
cord-277648-9kxwkcbl	235	20	,	,	,
cord-277648-9kxwkcbl	235	21	TNF	TNF	NNP
cord-277648-9kxwkcbl	235	22	,	,	,
cord-277648-9kxwkcbl	235	23	and	and	CC
cord-277648-9kxwkcbl	235	24	IFNG	IFNG	NNP
cord-277648-9kxwkcbl	235	25	are	be	VBP
cord-277648-9kxwkcbl	235	26	predicted	predict	VBN
cord-277648-9kxwkcbl	235	27	to	to	TO
cord-277648-9kxwkcbl	235	28	regulate	regulate	VB
cord-277648-9kxwkcbl	235	29	FOS	FOS	NNP
cord-277648-9kxwkcbl	235	30	and	and	CC
cord-277648-9kxwkcbl	235	31	JUN	JUN	NNP
cord-277648-9kxwkcbl	235	32	,	,	,
cord-277648-9kxwkcbl	235	33	with	with	IN
cord-277648-9kxwkcbl	235	34	IL1A	IL1A	NNP
cord-277648-9kxwkcbl	235	35	additionally	additionally	RB
cord-277648-9kxwkcbl	235	36	regulating	regulate	VBG
cord-277648-9kxwkcbl	235	37	JUN	JUN	NNP
cord-277648-9kxwkcbl	235	38	.	.	.
cord-277648-9kxwkcbl	236	1	Exploring	explore	VBG
cord-277648-9kxwkcbl	236	2	the	the	DT
cord-277648-9kxwkcbl	236	3	expression	expression	NN
cord-277648-9kxwkcbl	236	4	of	of	IN
cord-277648-9kxwkcbl	236	5	these	these	DT
cord-277648-9kxwkcbl	236	6	16	16	CD
cord-277648-9kxwkcbl	236	7	ligands	ligand	NNS
cord-277648-9kxwkcbl	236	8	across	across	IN
cord-277648-9kxwkcbl	236	9	the	the	DT
cord-277648-9kxwkcbl	236	10	diversity	diversity	NN
cord-277648-9kxwkcbl	236	11	of	of	IN
cord-277648-9kxwkcbl	236	12	BALF	BALF	NNP
cord-277648-9kxwkcbl	236	13	cell	cell	NN
cord-277648-9kxwkcbl	236	14	types	type	NNS
cord-277648-9kxwkcbl	236	15	indicates	indicate	VBZ
cord-277648-9kxwkcbl	236	16	that	that	IN
cord-277648-9kxwkcbl	236	17	MPs	mp	NNS
cord-277648-9kxwkcbl	236	18	and	and	CC
cord-277648-9kxwkcbl	236	19	neutrophils	neutrophil	NNS
cord-277648-9kxwkcbl	236	20	may	may	MD
cord-277648-9kxwkcbl	236	21	act	act	VB
cord-277648-9kxwkcbl	236	22	as	as	IN
cord-277648-9kxwkcbl	236	23	"	"	``
cord-277648-9kxwkcbl	236	24	sender	sender	NN
cord-277648-9kxwkcbl	236	25	cells	cell	NNS
cord-277648-9kxwkcbl	236	26	"	"	''
cord-277648-9kxwkcbl	236	27	signaling	signal	VBG
cord-277648-9kxwkcbl	236	28	to	to	IN
cord-277648-9kxwkcbl	236	29	the	the	DT
cord-277648-9kxwkcbl	236	30	epithelium	epithelium	NN
cord-277648-9kxwkcbl	236	31	,	,	,
cord-277648-9kxwkcbl	236	32	as	as	IN
cord-277648-9kxwkcbl	236	33	suggested	suggest	VBN
cord-277648-9kxwkcbl	236	34	in	in	IN
cord-277648-9kxwkcbl	236	35	recent	recent	JJ
cord-277648-9kxwkcbl	236	36	reports	report	NNS
cord-277648-9kxwkcbl	236	37	[	[	-LRB-
cord-277648-9kxwkcbl	236	38	21	21	CD
cord-277648-9kxwkcbl	236	39	,	,	,
cord-277648-9kxwkcbl	236	40	28	28	CD
cord-277648-9kxwkcbl	236	41	,	,	,
cord-277648-9kxwkcbl	236	42	53	53	CD
cord-277648-9kxwkcbl	236	43	]	]	-RRB-
cord-277648-9kxwkcbl	236	44	.	.	.
cord-277648-9kxwkcbl	237	1	In	in	IN
cord-277648-9kxwkcbl	237	2	particular	particular	JJ
cord-277648-9kxwkcbl	237	3	,	,	,
cord-277648-9kxwkcbl	237	4	aberrant	aberrant	JJ
cord-277648-9kxwkcbl	237	5	neutrophil	neutrophil	NN
cord-277648-9kxwkcbl	237	6	responses	response	NNS
cord-277648-9kxwkcbl	237	7	have	have	VBP
cord-277648-9kxwkcbl	237	8	been	be	VBN
cord-277648-9kxwkcbl	237	9	implicated	implicate	VBN
cord-277648-9kxwkcbl	237	10	in	in	IN
cord-277648-9kxwkcbl	237	11	severe	severe	JJ
cord-277648-9kxwkcbl	237	12	COVID-19	covid-19	NN
cord-277648-9kxwkcbl	237	13	through	through	IN
cord-277648-9kxwkcbl	237	14	a	a	DT
cord-277648-9kxwkcbl	237	15	number	number	NN
cord-277648-9kxwkcbl	237	16	of	of	IN
cord-277648-9kxwkcbl	237	17	studies	study	NNS
cord-277648-9kxwkcbl	237	18	focusing	focus	VBG
cord-277648-9kxwkcbl	237	19	on	on	IN
cord-277648-9kxwkcbl	237	20	either	either	CC
cord-277648-9kxwkcbl	237	21	the	the	DT
cord-277648-9kxwkcbl	237	22	lung	lung	NN
cord-277648-9kxwkcbl	237	23	or	or	CC
cord-277648-9kxwkcbl	237	24	the	the	DT
cord-277648-9kxwkcbl	237	25	blood	blood	NN
cord-277648-9kxwkcbl	237	26	[	[	-LRB-
cord-277648-9kxwkcbl	237	27	21	21	CD
cord-277648-9kxwkcbl	237	28	,	,	,
cord-277648-9kxwkcbl	237	29	28	28	CD
cord-277648-9kxwkcbl	237	30	,	,	,
cord-277648-9kxwkcbl	237	31	34	34	CD
cord-277648-9kxwkcbl	237	32	,	,	,
cord-277648-9kxwkcbl	237	33	35	35	CD
cord-277648-9kxwkcbl	237	34	,	,	,
cord-277648-9kxwkcbl	237	35	36	36	CD
cord-277648-9kxwkcbl	237	36	,	,	,
cord-277648-9kxwkcbl	237	37	53	53	CD
cord-277648-9kxwkcbl	237	38	]	]	-RRB-
cord-277648-9kxwkcbl	237	39	.	.	.
cord-277648-9kxwkcbl	238	1	On	on	IN
cord-277648-9kxwkcbl	238	2	further	further	JJ
cord-277648-9kxwkcbl	238	3	analysis	analysis	NN
cord-277648-9kxwkcbl	238	4	,	,	,
cord-277648-9kxwkcbl	238	5	we	-PRON-	PRP
cord-277648-9kxwkcbl	238	6	Our	-PRON-	PRP$
cord-277648-9kxwkcbl	238	7	analysis	analysis	NN
cord-277648-9kxwkcbl	238	8	of	of	IN
cord-277648-9kxwkcbl	238	9	the	the	DT
cord-277648-9kxwkcbl	238	10	transcriptional	transcriptional	JJ
cord-277648-9kxwkcbl	238	11	regulation	regulation	NN
cord-277648-9kxwkcbl	238	12	of	of	IN
cord-277648-9kxwkcbl	238	13	cell	cell	NN
cord-277648-9kxwkcbl	238	14	surface	surface	NN
cord-277648-9kxwkcbl	238	15	proteins	protein	NNS
cord-277648-9kxwkcbl	238	16	implicated	implicate	VBD
cord-277648-9kxwkcbl	238	17	AREG	AREG	NNP
cord-277648-9kxwkcbl	238	18	as	as	IN
cord-277648-9kxwkcbl	238	19	a	a	DT
cord-277648-9kxwkcbl	238	20	potential	potential	JJ
cord-277648-9kxwkcbl	238	21	marker	marker	NN
cord-277648-9kxwkcbl	238	22	unique	unique	JJ
cord-277648-9kxwkcbl	238	23	to	to	IN
cord-277648-9kxwkcbl	238	24	severe	severe	JJ
cord-277648-9kxwkcbl	238	25	disease	disease	NN
cord-277648-9kxwkcbl	238	26	in	in	IN
cord-277648-9kxwkcbl	238	27	pDCs	pDCs	NNP
cord-277648-9kxwkcbl	238	28	.	.	.
cord-277648-9kxwkcbl	239	1	This	this	DT
cord-277648-9kxwkcbl	239	2	finding	finding	NN
cord-277648-9kxwkcbl	239	3	appears	appear	VBZ
cord-277648-9kxwkcbl	239	4	consistent	consistent	JJ
cord-277648-9kxwkcbl	239	5	with	with	IN
cord-277648-9kxwkcbl	239	6	previous	previous	JJ
cord-277648-9kxwkcbl	239	7	literature	literature	NN
cord-277648-9kxwkcbl	239	8	showing	show	VBG
cord-277648-9kxwkcbl	239	9	that	that	IN
cord-277648-9kxwkcbl	239	10	amphiregulin	amphiregulin	NNP
cord-277648-9kxwkcbl	239	11	aids	aids	NNP
cord-277648-9kxwkcbl	239	12	in	in	IN
cord-277648-9kxwkcbl	239	13	the	the	DT
cord-277648-9kxwkcbl	239	14	maintenance	maintenance	NN
cord-277648-9kxwkcbl	239	15	of	of	IN
cord-277648-9kxwkcbl	239	16	epithelial	epithelial	JJ
cord-277648-9kxwkcbl	239	17	integrity	integrity	NN
cord-277648-9kxwkcbl	239	18	and	and	CC
cord-277648-9kxwkcbl	239	19	tissue	tissue	NN
cord-277648-9kxwkcbl	239	20	repair	repair	NN
cord-277648-9kxwkcbl	239	21	during	during	IN
cord-277648-9kxwkcbl	239	22	infection	infection	NN
cord-277648-9kxwkcbl	239	23	or	or	CC
cord-277648-9kxwkcbl	239	24	injury	injury	NN
cord-277648-9kxwkcbl	239	25	,	,	,
cord-277648-9kxwkcbl	239	26	[	[	-LRB-
cord-277648-9kxwkcbl	239	27	45	45	CD
cord-277648-9kxwkcbl	239	28	,	,	,
cord-277648-9kxwkcbl	239	29	61	61	CD
cord-277648-9kxwkcbl	239	30	]	]	-RRB-
cord-277648-9kxwkcbl	239	31	as	as	IN
cord-277648-9kxwkcbl	239	32	patients	patient	NNS
cord-277648-9kxwkcbl	239	33	with	with	IN
cord-277648-9kxwkcbl	239	34	severe	severe	JJ
cord-277648-9kxwkcbl	239	35	COVID-19	covid-19	JJ
cord-277648-9kxwkcbl	239	36	experience	experience	NN
cord-277648-9kxwkcbl	239	37	extreme	extreme	JJ
cord-277648-9kxwkcbl	239	38	pulmonary	pulmonary	JJ
cord-277648-9kxwkcbl	239	39	damage	damage	NN
cord-277648-9kxwkcbl	239	40	.	.	.
cord-277648-9kxwkcbl	240	1	Expanding	expand	VBG
cord-277648-9kxwkcbl	240	2	on	on	IN
cord-277648-9kxwkcbl	240	3	this	this	DT
cord-277648-9kxwkcbl	240	4	knowledge	knowledge	NN
cord-277648-9kxwkcbl	240	5	,	,	,
cord-277648-9kxwkcbl	240	6	we	-PRON-	PRP
cord-277648-9kxwkcbl	240	7	utilized	utilize	VBD
cord-277648-9kxwkcbl	240	8	ligand	ligand	NN
cord-277648-9kxwkcbl	240	9	-	-	HYPH
cord-277648-9kxwkcbl	240	10	receptor	receptor	NN
cord-277648-9kxwkcbl	240	11	network	network	NN
cord-277648-9kxwkcbl	240	12	analysis	analysis	NN
cord-277648-9kxwkcbl	240	13	to	to	TO
cord-277648-9kxwkcbl	240	14	provide	provide	VB
cord-277648-9kxwkcbl	240	15	orthogonal	orthogonal	JJ
cord-277648-9kxwkcbl	240	16	information	information	NN
cord-277648-9kxwkcbl	240	17	suggesting	suggest	VBG
cord-277648-9kxwkcbl	240	18	how	how	WRB
cord-277648-9kxwkcbl	240	19	pDC	pDC	NNP
cord-277648-9kxwkcbl	240	20	differentially	differentially	RB
cord-277648-9kxwkcbl	240	21	expressed	express	VBD
cord-277648-9kxwkcbl	240	22	genes	gene	NNS
cord-277648-9kxwkcbl	240	23	,	,	,
cord-277648-9kxwkcbl	240	24	including	include	VBG
cord-277648-9kxwkcbl	240	25	AREG	AREG	NNP
cord-277648-9kxwkcbl	240	26	,	,	,
cord-277648-9kxwkcbl	240	27	may	may	MD
cord-277648-9kxwkcbl	240	28	be	be	VB
cord-277648-9kxwkcbl	240	29	regulated	regulate	VBN
cord-277648-9kxwkcbl	240	30	through	through	IN
cord-277648-9kxwkcbl	240	31	soluble	soluble	JJ
cord-277648-9kxwkcbl	240	32	or	or	CC
cord-277648-9kxwkcbl	240	33	cell	cell	NN
cord-277648-9kxwkcbl	240	34	-	-	HYPH
cord-277648-9kxwkcbl	240	35	surface	surface	NN
cord-277648-9kxwkcbl	240	36	mediators	mediator	NNS
cord-277648-9kxwkcbl	240	37	.	.	.
cord-277648-9kxwkcbl	241	1	NicheNet	NicheNet	NNP
cord-277648-9kxwkcbl	241	2	revealed	reveal	VBD
cord-277648-9kxwkcbl	241	3	that	that	IN
cord-277648-9kxwkcbl	241	4	MPs	mp	NNS
cord-277648-9kxwkcbl	241	5	and	and	CC
cord-277648-9kxwkcbl	241	6	neutrophils	neutrophil	NNS
cord-277648-9kxwkcbl	241	7	appear	appear	VBP
cord-277648-9kxwkcbl	241	8	to	to	TO
cord-277648-9kxwkcbl	241	9	signal	signal	VB
cord-277648-9kxwkcbl	241	10	to	to	IN
cord-277648-9kxwkcbl	241	11	pDCs	pdcs	VB
cord-277648-9kxwkcbl	241	12	through	through	IN
cord-277648-9kxwkcbl	241	13	SPP1	SPP1	NNP
cord-277648-9kxwkcbl	241	14	/	/	SYM
cord-277648-9kxwkcbl	241	15	IL6	il6	NN
cord-277648-9kxwkcbl	241	16	and	and	CC
cord-277648-9kxwkcbl	241	17	IL1B	il1b	VB
cord-277648-9kxwkcbl	241	18	respectively	respectively	RB
cord-277648-9kxwkcbl	241	19	to	to	TO
cord-277648-9kxwkcbl	241	20	regulate	regulate	VB
cord-277648-9kxwkcbl	241	21	the	the	DT
cord-277648-9kxwkcbl	241	22	expression	expression	NN
cord-277648-9kxwkcbl	241	23	of	of	IN
cord-277648-9kxwkcbl	241	24	AREG	AREG	NNP
cord-277648-9kxwkcbl	241	25	as	as	RB
cord-277648-9kxwkcbl	241	26	well	well	RB
cord-277648-9kxwkcbl	241	27	as	as	IN
cord-277648-9kxwkcbl	241	28	various	various	JJ
cord-277648-9kxwkcbl	241	29	other	other	JJ
cord-277648-9kxwkcbl	241	30	genes	gene	NNS
cord-277648-9kxwkcbl	241	31	.	.	.
cord-277648-9kxwkcbl	242	1	SPP1	SPP1	NNS
cord-277648-9kxwkcbl	242	2	in	in	IN
cord-277648-9kxwkcbl	242	3	particular	particular	JJ
cord-277648-9kxwkcbl	242	4	appears	appear	VBZ
cord-277648-9kxwkcbl	242	5	to	to	TO
cord-277648-9kxwkcbl	242	6	be	be	VB
cord-277648-9kxwkcbl	242	7	better	well	RBR
cord-277648-9kxwkcbl	242	8	-	-	HYPH
cord-277648-9kxwkcbl	242	9	evidenced	evidence	VBN
cord-277648-9kxwkcbl	242	10	than	than	IN
cord-277648-9kxwkcbl	242	11	IL6	il6	NN
cord-277648-9kxwkcbl	242	12	and	and	CC
cord-277648-9kxwkcbl	242	13	IL1B	il1b	NN
cord-277648-9kxwkcbl	242	14	as	as	IN
cord-277648-9kxwkcbl	242	15	its	-PRON-	PRP$
cord-277648-9kxwkcbl	242	16	active	active	JJ
cord-277648-9kxwkcbl	242	17	receptors	receptor	NNS
cord-277648-9kxwkcbl	242	18	CD44	CD44	NNP
cord-277648-9kxwkcbl	242	19	and	and	CC
cord-277648-9kxwkcbl	242	20	ITGB1	ITGB1	NNP
cord-277648-9kxwkcbl	242	21	are	be	VBP
cord-277648-9kxwkcbl	242	22	present	present	JJ
cord-277648-9kxwkcbl	242	23	on	on	IN
cord-277648-9kxwkcbl	242	24	over	over	IN
cord-277648-9kxwkcbl	242	25	20	20	CD
cord-277648-9kxwkcbl	242	26	%	%	NN
cord-277648-9kxwkcbl	242	27	of	of	IN
cord-277648-9kxwkcbl	242	28	pDCs	pDCs	NNP
cord-277648-9kxwkcbl	242	29	in	in	IN
cord-277648-9kxwkcbl	242	30	severe	severe	JJ
cord-277648-9kxwkcbl	242	31	donors	donor	NNS
cord-277648-9kxwkcbl	242	32	.	.	.
cord-277648-9kxwkcbl	243	1	Our	-PRON-	PRP$
cord-277648-9kxwkcbl	243	2	network	network	NN
cord-277648-9kxwkcbl	243	3	analysis	analysis	NN
cord-277648-9kxwkcbl	243	4	suggests	suggest	VBZ
cord-277648-9kxwkcbl	243	5	that	that	IN
cord-277648-9kxwkcbl	243	6	the	the	DT
cord-277648-9kxwkcbl	243	7	expansion	expansion	NN
cord-277648-9kxwkcbl	243	8	of	of	IN
cord-277648-9kxwkcbl	243	9	a	a	DT
cord-277648-9kxwkcbl	243	10	population	population	NN
cord-277648-9kxwkcbl	243	11	of	of	IN
cord-277648-9kxwkcbl	243	12	SPP1-expressing	SPP1-expressing	NNP
cord-277648-9kxwkcbl	243	13	MPs	mp	NNS
cord-277648-9kxwkcbl	243	14	during	during	IN
cord-277648-9kxwkcbl	243	15	severe	severe	JJ
cord-277648-9kxwkcbl	243	16	disease	disease	NN
cord-277648-9kxwkcbl	243	17	,	,	,
cord-277648-9kxwkcbl	243	18	observed	observe	VBD
cord-277648-9kxwkcbl	243	19	here	here	RB
cord-277648-9kxwkcbl	243	20	and	and	CC
cord-277648-9kxwkcbl	243	21	in	in	IN
cord-277648-9kxwkcbl	243	22	Liao	Liao	NNP
cord-277648-9kxwkcbl	243	23	et	et	NNP
cord-277648-9kxwkcbl	243	24	al	al	NNP
cord-277648-9kxwkcbl	243	25	.	.	.
cord-277648-9kxwkcbl	244	1	[	[	-LRB-
cord-277648-9kxwkcbl	244	2	27	27	CD
cord-277648-9kxwkcbl	244	3	]	]	-RRB-
cord-277648-9kxwkcbl	244	4	,	,	,
cord-277648-9kxwkcbl	244	5	may	may	MD
cord-277648-9kxwkcbl	244	6	partly	partly	RB
cord-277648-9kxwkcbl	244	7	account	account	VB
cord-277648-9kxwkcbl	244	8	for	for	IN
cord-277648-9kxwkcbl	244	9	the	the	DT
cord-277648-9kxwkcbl	244	10	upregulation	upregulation	NN
cord-277648-9kxwkcbl	244	11	of	of	IN
cord-277648-9kxwkcbl	244	12	AREG	AREG	NNP
cord-277648-9kxwkcbl	244	13	by	by	IN
cord-277648-9kxwkcbl	244	14	pDCs	pDCs	NNP
cord-277648-9kxwkcbl	244	15	.	.	.
cord-277648-9kxwkcbl	245	1	We	-PRON-	PRP
cord-277648-9kxwkcbl	245	2	recommend	recommend	VBP
cord-277648-9kxwkcbl	245	3	further	further	JJ
cord-277648-9kxwkcbl	245	4	study	study	NN
cord-277648-9kxwkcbl	245	5	of	of	IN
cord-277648-9kxwkcbl	245	6	the	the	DT
cord-277648-9kxwkcbl	245	7	potential	potential	NN
cord-277648-9kxwkcbl	245	8	for	for	IN
cord-277648-9kxwkcbl	245	9	AREG	AREG	NNP
cord-277648-9kxwkcbl	245	10	induction	induction	NN
cord-277648-9kxwkcbl	245	11	by	by	IN
cord-277648-9kxwkcbl	245	12	SPP1	SPP1	NNP
cord-277648-9kxwkcbl	245	13	in	in	IN
cord-277648-9kxwkcbl	245	14	addition	addition	NN
cord-277648-9kxwkcbl	245	15	to	to	IN
cord-277648-9kxwkcbl	245	16	investigation	investigation	NN
cord-277648-9kxwkcbl	245	17	of	of	IN
cord-277648-9kxwkcbl	245	18	AREG	AREG	NNP
cord-277648-9kxwkcbl	245	19	surface	surface	VBP
cord-277648-9kxwkcbl	245	20	expression	expression	NN
cord-277648-9kxwkcbl	245	21	as	as	IN
cord-277648-9kxwkcbl	245	22	a	a	DT
cord-277648-9kxwkcbl	245	23	marker	marker	NN
cord-277648-9kxwkcbl	245	24	of	of	IN
cord-277648-9kxwkcbl	245	25	severe	severe	JJ
cord-277648-9kxwkcbl	245	26	disease	disease	NN
cord-277648-9kxwkcbl	245	27	.	.	.
cord-277648-9kxwkcbl	246	1	Immune	immune	JJ
cord-277648-9kxwkcbl	246	2	blockades	blockade	NNS
cord-277648-9kxwkcbl	246	3	,	,	,
cord-277648-9kxwkcbl	246	4	including	include	VBG
cord-277648-9kxwkcbl	246	5	the	the	DT
cord-277648-9kxwkcbl	246	6	IL-6R	IL-6R	NNP
cord-277648-9kxwkcbl	246	7	antagonist	antagonist	NN
cord-277648-9kxwkcbl	246	8	Tocilizumab	Tocilizumab	NNP
cord-277648-9kxwkcbl	246	9	,	,	,
cord-277648-9kxwkcbl	246	10	are	be	VBP
cord-277648-9kxwkcbl	246	11	a	a	DT
cord-277648-9kxwkcbl	246	12	class	class	NN
cord-277648-9kxwkcbl	246	13	of	of	IN
cord-277648-9kxwkcbl	246	14	treatments	treatment	NNS
cord-277648-9kxwkcbl	246	15	currently	currently	RB
cord-277648-9kxwkcbl	246	16	under	under	IN
cord-277648-9kxwkcbl	246	17	clinical	clinical	JJ
cord-277648-9kxwkcbl	246	18	use	use	NN
cord-277648-9kxwkcbl	246	19	and	and	CC
cord-277648-9kxwkcbl	246	20	research	research	NN
cord-277648-9kxwkcbl	246	21	for	for	IN
cord-277648-9kxwkcbl	246	22	COVID-19	COVID-19	NNP
cord-277648-9kxwkcbl	246	23	intended	intend	VBN
cord-277648-9kxwkcbl	246	24	to	to	TO
cord-277648-9kxwkcbl	246	25	dampen	dampen	VB
cord-277648-9kxwkcbl	246	26	the	the	DT
cord-277648-9kxwkcbl	246	27	hyperactive	hyperactive	JJ
cord-277648-9kxwkcbl	246	28	immune	immune	JJ
cord-277648-9kxwkcbl	246	29	response	response	NN
cord-277648-9kxwkcbl	246	30	by	by	IN
cord-277648-9kxwkcbl	246	31	targeting	target	VBG
cord-277648-9kxwkcbl	246	32	key	key	JJ
cord-277648-9kxwkcbl	246	33	nodes	node	NNS
cord-277648-9kxwkcbl	246	34	in	in	IN
cord-277648-9kxwkcbl	246	35	a	a	DT
cord-277648-9kxwkcbl	246	36	signaling	signal	VBG
cord-277648-9kxwkcbl	246	37	network	network	NN
cord-277648-9kxwkcbl	246	38	[	[	-LRB-
cord-277648-9kxwkcbl	246	39	23	23	CD
cord-277648-9kxwkcbl	246	40	,	,	,
cord-277648-9kxwkcbl	246	41	30	30	CD
cord-277648-9kxwkcbl	246	42	,	,	,
cord-277648-9kxwkcbl	246	43	31	31	CD
cord-277648-9kxwkcbl	246	44	]	]	-RRB-
cord-277648-9kxwkcbl	246	45	.	.	.
cord-277648-9kxwkcbl	247	1	Here	here	RB
cord-277648-9kxwkcbl	247	2	,	,	,
cord-277648-9kxwkcbl	247	3	we	-PRON-	PRP
cord-277648-9kxwkcbl	247	4	sought	seek	VBD
cord-277648-9kxwkcbl	247	5	to	to	TO
cord-277648-9kxwkcbl	247	6	utilize	utilize	VB
cord-277648-9kxwkcbl	247	7	ligand	ligand	NN
cord-277648-9kxwkcbl	247	8	-	-	HYPH
cord-277648-9kxwkcbl	247	9	receptor	receptor	NN
cord-277648-9kxwkcbl	247	10	network	network	NN
cord-277648-9kxwkcbl	247	11	analysis	analysis	NN
cord-277648-9kxwkcbl	247	12	to	to	TO
cord-277648-9kxwkcbl	247	13	nominate	nominate	VB
cord-277648-9kxwkcbl	247	14	ligands	ligand	NNS
cord-277648-9kxwkcbl	247	15	as	as	IN
cord-277648-9kxwkcbl	247	16	potential	potential	JJ
cord-277648-9kxwkcbl	247	17	key	key	JJ
cord-277648-9kxwkcbl	247	18	regulators	regulator	NNS
cord-277648-9kxwkcbl	247	19	of	of	IN
cord-277648-9kxwkcbl	247	20	severity	severity	NN
cord-277648-9kxwkcbl	247	21	-	-	HYPH
cord-277648-9kxwkcbl	247	22	specific	specific	JJ
cord-277648-9kxwkcbl	247	23	dysregulation	dysregulation	NN
cord-277648-9kxwkcbl	247	24	in	in	IN
cord-277648-9kxwkcbl	247	25	the	the	DT
cord-277648-9kxwkcbl	247	26	lung	lung	NN
cord-277648-9kxwkcbl	247	27	microenvironment	microenvironment	NN
cord-277648-9kxwkcbl	247	28	during	during	IN
cord-277648-9kxwkcbl	247	29	severe	severe	JJ
cord-277648-9kxwkcbl	247	30	COVID-19	covid-19	NN
cord-277648-9kxwkcbl	247	31	.	.	.
cord-277648-9kxwkcbl	248	1	Our	-PRON-	PRP$
cord-277648-9kxwkcbl	248	2	analysis	analysis	NN
cord-277648-9kxwkcbl	248	3	suggests	suggest	VBZ
cord-277648-9kxwkcbl	248	4	IFNG	IFNG	NNP
cord-277648-9kxwkcbl	248	5	,	,	,
cord-277648-9kxwkcbl	248	6	IL18	IL18	NNP
cord-277648-9kxwkcbl	248	7	,	,	,
cord-277648-9kxwkcbl	248	8	CCL3	CCL3	NNP
cord-277648-9kxwkcbl	248	9	,	,	,
cord-277648-9kxwkcbl	248	10	CCL8	CCL8	NNP
cord-277648-9kxwkcbl	248	11	,	,	,
cord-277648-9kxwkcbl	248	12	and	and	CC
cord-277648-9kxwkcbl	248	13	SPP1	SPP1	NNP
cord-277648-9kxwkcbl	248	14	as	as	IN
cord-277648-9kxwkcbl	248	15	candidate	candidate	NN
cord-277648-9kxwkcbl	248	16	"	"	``
cord-277648-9kxwkcbl	248	17	pan	pan	NN
cord-277648-9kxwkcbl	248	18	-	-	HYPH
cord-277648-9kxwkcbl	248	19	ligands	ligand	NNS
cord-277648-9kxwkcbl	248	20	"	"	''
cord-277648-9kxwkcbl	248	21	that	that	WDT
cord-277648-9kxwkcbl	248	22	may	may	MD
cord-277648-9kxwkcbl	248	23	induce	induce	VB
cord-277648-9kxwkcbl	248	24	transcriptional	transcriptional	JJ
cord-277648-9kxwkcbl	248	25	regulation	regulation	NN
cord-277648-9kxwkcbl	248	26	in	in	IN
cord-277648-9kxwkcbl	248	27	over	over	IN
cord-277648-9kxwkcbl	248	28	one	one	CD
cord-277648-9kxwkcbl	248	29	-	-	HYPH
cord-277648-9kxwkcbl	248	30	third	third	NN
cord-277648-9kxwkcbl	248	31	of	of	IN
cord-277648-9kxwkcbl	248	32	cell	cell	NN
cord-277648-9kxwkcbl	248	33	types	type	NNS
cord-277648-9kxwkcbl	248	34	identified	identify	VBN
cord-277648-9kxwkcbl	248	35	in	in	IN
cord-277648-9kxwkcbl	248	36	the	the	DT
cord-277648-9kxwkcbl	248	37	BALF	BALF	NNP
cord-277648-9kxwkcbl	248	38	during	during	IN
cord-277648-9kxwkcbl	248	39	severe	severe	JJ
cord-277648-9kxwkcbl	248	40	disease	disease	NN
cord-277648-9kxwkcbl	248	41	.	.	.
cord-277648-9kxwkcbl	249	1	Notably	notably	RB
cord-277648-9kxwkcbl	249	2	,	,	,
cord-277648-9kxwkcbl	249	3	we	-PRON-	PRP
cord-277648-9kxwkcbl	249	4	did	do	VBD
cord-277648-9kxwkcbl	249	5	not	not	RB
cord-277648-9kxwkcbl	249	6	identify	identify	VB
cord-277648-9kxwkcbl	249	7	IL6	IL6	NNP
cord-277648-9kxwkcbl	249	8	as	as	IN
cord-277648-9kxwkcbl	249	9	a	a	DT
cord-277648-9kxwkcbl	249	10	potential	potential	JJ
cord-277648-9kxwkcbl	249	11	pan	pan	NN
cord-277648-9kxwkcbl	249	12	-	-	NN
cord-277648-9kxwkcbl	249	13	ligand	ligand	NN
cord-277648-9kxwkcbl	249	14	as	as	IN
cord-277648-9kxwkcbl	249	15	its	-PRON-	PRP$
cord-277648-9kxwkcbl	249	16	differential	differential	JJ
cord-277648-9kxwkcbl	249	17	expression	expression	NN
cord-277648-9kxwkcbl	249	18	between	between	IN
cord-277648-9kxwkcbl	249	19	moderate	moderate	JJ
cord-277648-9kxwkcbl	249	20	and	and	CC
cord-277648-9kxwkcbl	249	21	severe	severe	JJ
cord-277648-9kxwkcbl	249	22	patients	patient	NNS
cord-277648-9kxwkcbl	249	23	in	in	IN
cord-277648-9kxwkcbl	249	24	our	-PRON-	PRP$
cord-277648-9kxwkcbl	249	25	study	study	NN
cord-277648-9kxwkcbl	249	26	was	be	VBD
cord-277648-9kxwkcbl	249	27	not	not	RB
cord-277648-9kxwkcbl	249	28	statistically	statistically	RB
cord-277648-9kxwkcbl	249	29	significant	significant	JJ
cord-277648-9kxwkcbl	249	30	in	in	IN
cord-277648-9kxwkcbl	249	31	any	any	DT
cord-277648-9kxwkcbl	249	32	cell	cell	NN
cord-277648-9kxwkcbl	249	33	type	type	NN
cord-277648-9kxwkcbl	249	34	.	.	.
cord-277648-9kxwkcbl	250	1	All	all	DT
cord-277648-9kxwkcbl	250	2	of	of	IN
cord-277648-9kxwkcbl	250	3	the	the	DT
cord-277648-9kxwkcbl	250	4	pan	pan	NN
cord-277648-9kxwkcbl	250	5	-	-	HYPH
cord-277648-9kxwkcbl	250	6	ligands	ligand	NNS
cord-277648-9kxwkcbl	250	7	we	-PRON-	PRP
cord-277648-9kxwkcbl	250	8	report	report	VBP
cord-277648-9kxwkcbl	250	9	have	have	VBP
cord-277648-9kxwkcbl	250	10	been	be	VBN
cord-277648-9kxwkcbl	250	11	previously	previously	RB
cord-277648-9kxwkcbl	250	12	implicated	implicate	VBN
cord-277648-9kxwkcbl	250	13	in	in	IN
cord-277648-9kxwkcbl	250	14	SARSr	SARSr	NNS
cord-277648-9kxwkcbl	250	15	-	-	HYPH
cord-277648-9kxwkcbl	250	16	CoV	cov	NN
cord-277648-9kxwkcbl	250	17	infection	infection	NN
cord-277648-9kxwkcbl	250	18	,	,	,
cord-277648-9kxwkcbl	250	19	with	with	IN
cord-277648-9kxwkcbl	250	20	IL-18	IL-18	NNP
cord-277648-9kxwkcbl	250	21	,	,	,
cord-277648-9kxwkcbl	250	22	CCL8	CCL8	NNP
cord-277648-9kxwkcbl	250	23	,	,	,
cord-277648-9kxwkcbl	250	24	and	and	CC
cord-277648-9kxwkcbl	250	25	IFN	IFN	NNP
cord-277648-9kxwkcbl	250	26	-	-	HYPH
cord-277648-9kxwkcbl	250	27	γ	γ	NNP
cord-277648-9kxwkcbl	250	28	having	have	VBG
cord-277648-9kxwkcbl	250	29	been	be	VBN
cord-277648-9kxwkcbl	250	30	detected	detect	VBN
cord-277648-9kxwkcbl	250	31	in	in	IN
cord-277648-9kxwkcbl	250	32	serum	serum	NN
cord-277648-9kxwkcbl	250	33	from	from	IN
cord-277648-9kxwkcbl	250	34	COVID-19	covid-19	CD
cord-277648-9kxwkcbl	250	35	patients	patient	NNS
cord-277648-9kxwkcbl	250	36	[	[	-LRB-
cord-277648-9kxwkcbl	250	37	9	9	CD
cord-277648-9kxwkcbl	250	38	,	,	,
cord-277648-9kxwkcbl	250	39	13	13	CD
cord-277648-9kxwkcbl	250	40	,	,	,
cord-277648-9kxwkcbl	250	41	14	14	CD
cord-277648-9kxwkcbl	250	42	]	]	-RRB-
cord-277648-9kxwkcbl	250	43	,	,	,
cord-277648-9kxwkcbl	250	44	SPP1	SPP1	NNP
cord-277648-9kxwkcbl	250	45	upregulation	upregulation	NN
cord-277648-9kxwkcbl	250	46	measured	measure	VBN
cord-277648-9kxwkcbl	250	47	in	in	IN
cord-277648-9kxwkcbl	250	48	microarrays	microarray	NNS
cord-277648-9kxwkcbl	250	49	from	from	IN
cord-277648-9kxwkcbl	250	50	SARS	SARS	NNP
cord-277648-9kxwkcbl	250	51	-	-	HYPH
cord-277648-9kxwkcbl	250	52	CoV	CoV	NNP
cord-277648-9kxwkcbl	250	53	-	-	HYPH
cord-277648-9kxwkcbl	250	54	infected	infect	VBN
cord-277648-9kxwkcbl	250	55	nonhuman	nonhuman	NN
cord-277648-9kxwkcbl	250	56	primates	primate	NNS
cord-277648-9kxwkcbl	250	57	,	,	,
cord-277648-9kxwkcbl	250	58	and	and	CC
cord-277648-9kxwkcbl	250	59	CCL3	CCL3	NNP
cord-277648-9kxwkcbl	250	60	,	,	,
cord-277648-9kxwkcbl	250	61	CCL8	CCL8	NNP
cord-277648-9kxwkcbl	250	62	,	,	,
cord-277648-9kxwkcbl	250	63	IL18	IL18	NNP
cord-277648-9kxwkcbl	250	64	,	,	,
cord-277648-9kxwkcbl	250	65	and	and	CC
cord-277648-9kxwkcbl	250	66	IFNG	IFNG	NNP
cord-277648-9kxwkcbl	250	67	upregulation	upregulation	NN
cord-277648-9kxwkcbl	250	68	detected	detect	VBD
cord-277648-9kxwkcbl	250	69	in	in	IN
cord-277648-9kxwkcbl	250	70	single	single	JJ
cord-277648-9kxwkcbl	250	71	-	-	HYPH
cord-277648-9kxwkcbl	250	72	cell	cell	NN
cord-277648-9kxwkcbl	250	73	or	or	CC
cord-277648-9kxwkcbl	250	74	bulk	bulk	JJ
cord-277648-9kxwkcbl	250	75	RNA	RNA	NNP
cord-277648-9kxwkcbl	250	76	-	-	HYPH
cord-277648-9kxwkcbl	250	77	seq	seq	NNP
cord-277648-9kxwkcbl	250	78	from	from	IN
cord-277648-9kxwkcbl	250	79	the	the	DT
cord-277648-9kxwkcbl	250	80	lungs	lung	NNS
cord-277648-9kxwkcbl	250	81	of	of	IN
cord-277648-9kxwkcbl	250	82	COVID-19	covid-19	CD
cord-277648-9kxwkcbl	250	83	patients	patient	NNS
cord-277648-9kxwkcbl	250	84	[	[	-LRB-
cord-277648-9kxwkcbl	250	85	21	21	CD
cord-277648-9kxwkcbl	250	86	,	,	,
cord-277648-9kxwkcbl	250	87	22	22	CD
cord-277648-9kxwkcbl	250	88	,	,	,
cord-277648-9kxwkcbl	250	89	27	27	CD
cord-277648-9kxwkcbl	250	90	,	,	,
cord-277648-9kxwkcbl	250	91	28	28	CD
cord-277648-9kxwkcbl	250	92	]	]	-RRB-
cord-277648-9kxwkcbl	250	93	.	.	.
cord-277648-9kxwkcbl	251	1	Importantly	importantly	RB
cord-277648-9kxwkcbl	251	2	,	,	,
cord-277648-9kxwkcbl	251	3	our	-PRON-	PRP$
cord-277648-9kxwkcbl	251	4	data	data	NN
cord-277648-9kxwkcbl	251	5	supports	support	VBZ
cord-277648-9kxwkcbl	251	6	accumulating	accumulate	VBG
cord-277648-9kxwkcbl	251	7	evidence	evidence	NN
cord-277648-9kxwkcbl	251	8	for	for	IN
cord-277648-9kxwkcbl	251	9	a	a	DT
cord-277648-9kxwkcbl	251	10	nuanced	nuanced	JJ
cord-277648-9kxwkcbl	251	11	interferon	interferon	NN
cord-277648-9kxwkcbl	251	12	response	response	NN
cord-277648-9kxwkcbl	251	13	in	in	IN
cord-277648-9kxwkcbl	251	14	COVID-19	COVID-19	NNP
cord-277648-9kxwkcbl	251	15	depending	depend	VBG
cord-277648-9kxwkcbl	251	16	on	on	IN
cord-277648-9kxwkcbl	251	17	disease	disease	NN
cord-277648-9kxwkcbl	251	18	severity	severity	NN
cord-277648-9kxwkcbl	251	19	,	,	,
cord-277648-9kxwkcbl	251	20	cell	cell	NN
cord-277648-9kxwkcbl	251	21	type	type	NN
cord-277648-9kxwkcbl	251	22	,	,	,
cord-277648-9kxwkcbl	251	23	and	and	CC
cord-277648-9kxwkcbl	251	24	local	local	JJ
cord-277648-9kxwkcbl	251	25	versus	versus	IN
cord-277648-9kxwkcbl	251	26	systemic	systemic	JJ
cord-277648-9kxwkcbl	251	27	immune	immune	JJ
cord-277648-9kxwkcbl	251	28	environment	environment	NN
cord-277648-9kxwkcbl	251	29	,	,	,
cord-277648-9kxwkcbl	251	30	as	as	IN
cord-277648-9kxwkcbl	251	31	discussed	discuss	VBN
cord-277648-9kxwkcbl	251	32	above	above	IN
cord-277648-9kxwkcbl	251	33	[	[	-LRB-
cord-277648-9kxwkcbl	251	34	25	25	CD
cord-277648-9kxwkcbl	251	35	,	,	,
cord-277648-9kxwkcbl	251	36	26	26	CD
cord-277648-9kxwkcbl	251	37	,	,	,
cord-277648-9kxwkcbl	251	38	28	28	CD
cord-277648-9kxwkcbl	251	39	,	,	,
cord-277648-9kxwkcbl	251	40	33	33	CD
cord-277648-9kxwkcbl	251	41	,	,	,
cord-277648-9kxwkcbl	251	42	34	34	CD
cord-277648-9kxwkcbl	251	43	,	,	,
cord-277648-9kxwkcbl	251	44	36	36	CD
cord-277648-9kxwkcbl	251	45	,	,	,
cord-277648-9kxwkcbl	251	46	55	55	CD
cord-277648-9kxwkcbl	251	47	]	]	-RRB-
cord-277648-9kxwkcbl	251	48	.	.	.
cord-277648-9kxwkcbl	252	1	We	-PRON-	PRP
cord-277648-9kxwkcbl	252	2	suspect	suspect	VBP
cord-277648-9kxwkcbl	252	3	that	that	IN
cord-277648-9kxwkcbl	252	4	treatment	treatment	NN
cord-277648-9kxwkcbl	252	5	strategies	strategy	NNS
cord-277648-9kxwkcbl	252	6	consisting	consist	VBG
cord-277648-9kxwkcbl	252	7	of	of	IN
cord-277648-9kxwkcbl	252	8	a	a	DT
cord-277648-9kxwkcbl	252	9	direct	direct	JJ
cord-277648-9kxwkcbl	252	10	type	type	NN
cord-277648-9kxwkcbl	252	11	II	II	NNP
cord-277648-9kxwkcbl	252	12	interferon	interferon	NN
cord-277648-9kxwkcbl	252	13	blockade	blockade	NN
cord-277648-9kxwkcbl	252	14	(	(	-LRB-
cord-277648-9kxwkcbl	252	15	NIH	NIH	NNP
cord-277648-9kxwkcbl	252	16	clinical	clinical	JJ
cord-277648-9kxwkcbl	252	17	trial	trial	NN
cord-277648-9kxwkcbl	252	18	NCT04324021	NCT04324021	NNP
cord-277648-9kxwkcbl	252	19	)	)	-RRB-
cord-277648-9kxwkcbl	252	20	[	[	-LRB-
cord-277648-9kxwkcbl	252	21	62	62	CD
cord-277648-9kxwkcbl	252	22	,	,	,
cord-277648-9kxwkcbl	252	23	63	63	CD
cord-277648-9kxwkcbl	252	24	]	]	-RRB-
cord-277648-9kxwkcbl	252	25	could	could	MD
cord-277648-9kxwkcbl	252	26	exert	exert	VB
cord-277648-9kxwkcbl	252	27	different	different	JJ
cord-277648-9kxwkcbl	252	28	effects	effect	NNS
cord-277648-9kxwkcbl	252	29	systemically	systemically	RB
cord-277648-9kxwkcbl	252	30	and	and	CC
cord-277648-9kxwkcbl	252	31	locally	locally	RB
cord-277648-9kxwkcbl	252	32	depending	depend	VBG
cord-277648-9kxwkcbl	252	33	on	on	IN
cord-277648-9kxwkcbl	252	34	the	the	DT
cord-277648-9kxwkcbl	252	35	patient	patient	NN
cord-277648-9kxwkcbl	252	36	's	's	POS
cord-277648-9kxwkcbl	252	37	clinical	clinical	JJ
cord-277648-9kxwkcbl	252	38	condition	condition	NN
cord-277648-9kxwkcbl	252	39	when	when	WRB
cord-277648-9kxwkcbl	252	40	administered	administer	VBN
cord-277648-9kxwkcbl	252	41	.	.	.
cord-277648-9kxwkcbl	253	1	Taken	take	VBN
cord-277648-9kxwkcbl	253	2	together	together	RB
cord-277648-9kxwkcbl	253	3	with	with	IN
cord-277648-9kxwkcbl	253	4	previous	previous	JJ
cord-277648-9kxwkcbl	253	5	findings	finding	NNS
cord-277648-9kxwkcbl	253	6	,	,	,
cord-277648-9kxwkcbl	253	7	our	-PRON-	PRP$
cord-277648-9kxwkcbl	253	8	data	datum	NNS
cord-277648-9kxwkcbl	253	9	suggests	suggest	VBZ
cord-277648-9kxwkcbl	253	10	IFNG	IFNG	NNP
cord-277648-9kxwkcbl	253	11	,	,	,
cord-277648-9kxwkcbl	253	12	IL18	IL18	NNP
cord-277648-9kxwkcbl	253	13	,	,	,
cord-277648-9kxwkcbl	253	14	CCL3	CCL3	NNP
cord-277648-9kxwkcbl	253	15	,	,	,
cord-277648-9kxwkcbl	253	16	CCL8	CCL8	NNP
cord-277648-9kxwkcbl	253	17	,	,	,
cord-277648-9kxwkcbl	253	18	and	and	CC
cord-277648-9kxwkcbl	253	19	SPP1	SPP1	NNP
cord-277648-9kxwkcbl	253	20	as	as	IN
cord-277648-9kxwkcbl	253	21	candidate	candidate	NN
cord-277648-9kxwkcbl	253	22	targets	target	NNS
cord-277648-9kxwkcbl	253	23	for	for	IN
cord-277648-9kxwkcbl	253	24	the	the	DT
cord-277648-9kxwkcbl	253	25	treatment	treatment	NN
cord-277648-9kxwkcbl	253	26	of	of	IN
cord-277648-9kxwkcbl	253	27	severe	severe	JJ
cord-277648-9kxwkcbl	253	28	COVID-19	covid-19	NN
cord-277648-9kxwkcbl	253	29	that	that	WDT
cord-277648-9kxwkcbl	253	30	warrant	warrant	VBP
cord-277648-9kxwkcbl	253	31	further	further	JJ
cord-277648-9kxwkcbl	253	32	study	study	NN
cord-277648-9kxwkcbl	253	33	.	.	.
cord-277648-9kxwkcbl	254	1	In	in	IN
cord-277648-9kxwkcbl	254	2	summary	summary	NN
cord-277648-9kxwkcbl	254	3	,	,	,
cord-277648-9kxwkcbl	254	4	our	-PRON-	PRP$
cord-277648-9kxwkcbl	254	5	findings	finding	NNS
cord-277648-9kxwkcbl	254	6	emphasize	emphasize	VBP
cord-277648-9kxwkcbl	254	7	unique	unique	JJ
cord-277648-9kxwkcbl	254	8	roles	role	NNS
cord-277648-9kxwkcbl	254	9	for	for	IN
cord-277648-9kxwkcbl	254	10	the	the	DT
cord-277648-9kxwkcbl	254	11	cells	cell	NNS
cord-277648-9kxwkcbl	254	12	of	of	IN
cord-277648-9kxwkcbl	254	13	the	the	DT
cord-277648-9kxwkcbl	254	14	lung	lung	NN
cord-277648-9kxwkcbl	254	15	microenvironment	microenvironment	NN
cord-277648-9kxwkcbl	254	16	and	and	CC
cord-277648-9kxwkcbl	254	17	systemic	systemic	JJ
cord-277648-9kxwkcbl	254	18	circulation	circulation	NN
cord-277648-9kxwkcbl	254	19	in	in	IN
cord-277648-9kxwkcbl	254	20	the	the	DT
cord-277648-9kxwkcbl	254	21	immunopathology	immunopathology	NN
cord-277648-9kxwkcbl	254	22	of	of	IN
cord-277648-9kxwkcbl	254	23	ARDS	ARDS	NNP
cord-277648-9kxwkcbl	254	24	and	and	CC
cord-277648-9kxwkcbl	254	25	severe	severe	JJ
cord-277648-9kxwkcbl	254	26	COVID-19	COVID-19	NNP
cord-277648-9kxwkcbl	254	27	.	.	.
cord-277648-9kxwkcbl	255	1	We	-PRON-	PRP
cord-277648-9kxwkcbl	255	2	recommend	recommend	VBP
cord-277648-9kxwkcbl	255	3	further	further	JJ
cord-277648-9kxwkcbl	255	4	investigation	investigation	NN
cord-277648-9kxwkcbl	255	5	of	of	IN
cord-277648-9kxwkcbl	255	6	differentially	differentially	RB
cord-277648-9kxwkcbl	255	7	expressed	express	VBN
cord-277648-9kxwkcbl	255	8	cell	cell	NN
cord-277648-9kxwkcbl	255	9	surface	surface	NN
cord-277648-9kxwkcbl	255	10	markers	marker	NNS
cord-277648-9kxwkcbl	255	11	to	to	TO
cord-277648-9kxwkcbl	255	12	determine	determine	VB
cord-277648-9kxwkcbl	255	13	their	-PRON-	PRP$
cord-277648-9kxwkcbl	255	14	utility	utility	NN
cord-277648-9kxwkcbl	255	15	in	in	IN
cord-277648-9kxwkcbl	255	16	immunophenotyping	immunophenotype	VBG
cord-277648-9kxwkcbl	255	17	patients	patient	NNS
cord-277648-9kxwkcbl	255	18	according	accord	VBG
cord-277648-9kxwkcbl	255	19	to	to	IN
cord-277648-9kxwkcbl	255	20	suspected	suspect	VBN
cord-277648-9kxwkcbl	255	21	disease	disease	NN
cord-277648-9kxwkcbl	255	22	course	course	NN
cord-277648-9kxwkcbl	255	23	to	to	TO
cord-277648-9kxwkcbl	255	24	aid	aid	VB
cord-277648-9kxwkcbl	255	25	in	in	IN
cord-277648-9kxwkcbl	255	26	triage	triage	NN
cord-277648-9kxwkcbl	255	27	or	or	CC
cord-277648-9kxwkcbl	255	28	to	to	TO
cord-277648-9kxwkcbl	255	29	inform	inform	VB
cord-277648-9kxwkcbl	255	30	optimal	optimal	JJ
cord-277648-9kxwkcbl	255	31	treatment	treatment	NN
cord-277648-9kxwkcbl	255	32	options	option	NNS
cord-277648-9kxwkcbl	255	33	.	.	.
cord-277648-9kxwkcbl	256	1	Our	-PRON-	PRP$
cord-277648-9kxwkcbl	256	2	transcriptional	transcriptional	JJ
cord-277648-9kxwkcbl	256	3	analyses	analysis	NNS
cord-277648-9kxwkcbl	256	4	show	show	VBP
cord-277648-9kxwkcbl	256	5	that	that	IN
cord-277648-9kxwkcbl	256	6	pathway	pathway	NN
cord-277648-9kxwkcbl	256	7	enrichment	enrichment	NN
cord-277648-9kxwkcbl	256	8	differs	differ	VBZ
cord-277648-9kxwkcbl	256	9	between	between	IN
cord-277648-9kxwkcbl	256	10	cells	cell	NNS
cord-277648-9kxwkcbl	256	11	of	of	IN
cord-277648-9kxwkcbl	256	12	the	the	DT
cord-277648-9kxwkcbl	256	13	lung	lung	NN
cord-277648-9kxwkcbl	256	14	and	and	CC
cord-277648-9kxwkcbl	256	15	blood	blood	NN
cord-277648-9kxwkcbl	256	16	,	,	,
cord-277648-9kxwkcbl	256	17	with	with	IN
cord-277648-9kxwkcbl	256	18	concerted	concerted	JJ
cord-277648-9kxwkcbl	256	19	immunological	immunological	JJ
cord-277648-9kxwkcbl	256	20	responses	response	NNS
cord-277648-9kxwkcbl	256	21	within	within	IN
cord-277648-9kxwkcbl	256	22	each	each	DT
cord-277648-9kxwkcbl	256	23	compartment	compartment	NN
cord-277648-9kxwkcbl	256	24	mirroring	mirror	VBG
cord-277648-9kxwkcbl	256	25	viral	viral	JJ
cord-277648-9kxwkcbl	256	26	respiratory	respiratory	JJ
cord-277648-9kxwkcbl	256	27	diseases	disease	NNS
cord-277648-9kxwkcbl	256	28	including	include	VBG
cord-277648-9kxwkcbl	256	29	influenza	influenza	NN
cord-277648-9kxwkcbl	256	30	,	,	,
cord-277648-9kxwkcbl	256	31	SARS	SARS	NNP
cord-277648-9kxwkcbl	256	32	,	,	,
cord-277648-9kxwkcbl	256	33	and	and	CC
cord-277648-9kxwkcbl	256	34	MERS	MERS	NNP
cord-277648-9kxwkcbl	256	35	.	.	.
cord-277648-9kxwkcbl	257	1	Finally	finally	RB
cord-277648-9kxwkcbl	257	2	,	,	,
cord-277648-9kxwkcbl	257	3	we	-PRON-	PRP
cord-277648-9kxwkcbl	257	4	nominate	nominate	VBP
cord-277648-9kxwkcbl	257	5	a	a	DT
cord-277648-9kxwkcbl	257	6	small	small	JJ
cord-277648-9kxwkcbl	257	7	number	number	NN
cord-277648-9kxwkcbl	257	8	of	of	IN
cord-277648-9kxwkcbl	257	9	broadly	broadly	RB
cord-277648-9kxwkcbl	257	10	-	-	HYPH
cord-277648-9kxwkcbl	257	11	acting	act	VBG
cord-277648-9kxwkcbl	257	12	ligands	ligand	NNS
cord-277648-9kxwkcbl	257	13	as	as	IN
cord-277648-9kxwkcbl	257	14	potential	potential	JJ
cord-277648-9kxwkcbl	257	15	drivers	driver	NNS
cord-277648-9kxwkcbl	257	16	of	of	IN
cord-277648-9kxwkcbl	257	17	severity	severity	NN
cord-277648-9kxwkcbl	257	18	-	-	HYPH
cord-277648-9kxwkcbl	257	19	specific	specific	JJ
cord-277648-9kxwkcbl	257	20	transcriptional	transcriptional	JJ
cord-277648-9kxwkcbl	257	21	regulation	regulation	NN
cord-277648-9kxwkcbl	257	22	in	in	IN
cord-277648-9kxwkcbl	257	23	the	the	DT
cord-277648-9kxwkcbl	257	24	severely	severely	RB
cord-277648-9kxwkcbl	257	25	damaged	damage	VBN
cord-277648-9kxwkcbl	257	26	lung	lung	NN
cord-277648-9kxwkcbl	257	27	microenvironment	microenvironment	NN
cord-277648-9kxwkcbl	257	28	of	of	IN
cord-277648-9kxwkcbl	257	29	COVID-19	covid-19	JJ
cord-277648-9kxwkcbl	257	30	patients	patient	NNS
cord-277648-9kxwkcbl	257	31	.	.	.
cord-277648-9kxwkcbl	258	1	All	all	DT
cord-277648-9kxwkcbl	258	2	single	single	JJ
cord-277648-9kxwkcbl	258	3	cell	cell	NN
cord-277648-9kxwkcbl	258	4	RNA	rna	NN
cord-277648-9kxwkcbl	258	5	-	-	HYPH
cord-277648-9kxwkcbl	258	6	sequencing	sequence	VBG
cord-277648-9kxwkcbl	258	7	(	(	-LRB-
cord-277648-9kxwkcbl	258	8	scRNA	scRNA	NNP
cord-277648-9kxwkcbl	258	9	-	-	HYPH
cord-277648-9kxwkcbl	258	10	seq	seq	NN
cord-277648-9kxwkcbl	258	11	)	)	-RRB-
cord-277648-9kxwkcbl	258	12	data	datum	NNS
cord-277648-9kxwkcbl	258	13	used	use	VBN
cord-277648-9kxwkcbl	258	14	in	in	IN
cord-277648-9kxwkcbl	258	15	this	this	DT
cord-277648-9kxwkcbl	258	16	analysis	analysis	NN
cord-277648-9kxwkcbl	258	17	were	be	VBD
cord-277648-9kxwkcbl	258	18	obtained	obtain	VBN
cord-277648-9kxwkcbl	258	19	from	from	IN
cord-277648-9kxwkcbl	258	20	publicly	publicly	RB
cord-277648-9kxwkcbl	258	21	available	available	JJ
cord-277648-9kxwkcbl	258	22	datasets	dataset	NNS
cord-277648-9kxwkcbl	258	23	.	.	.
cord-277648-9kxwkcbl	259	1	BALF	BALF	NNP
cord-277648-9kxwkcbl	259	2	scRNA	scRNA	NNP
cord-277648-9kxwkcbl	259	3	-	-	HYPH
cord-277648-9kxwkcbl	259	4	seq	seq	NN
cord-277648-9kxwkcbl	259	5	gene	gene	NN
cord-277648-9kxwkcbl	259	6	-	-	HYPH
cord-277648-9kxwkcbl	259	7	barcode	barcode	NN
cord-277648-9kxwkcbl	259	8	matrices	matrix	NNS
cord-277648-9kxwkcbl	259	9	from	from	IN
cord-277648-9kxwkcbl	259	10	9	9	CD
cord-277648-9kxwkcbl	259	11	COVID-19	covid-19	CD
cord-277648-9kxwkcbl	259	12	patients	patient	NNS
cord-277648-9kxwkcbl	259	13	(	(	-LRB-
cord-277648-9kxwkcbl	259	14	6	6	CD
cord-277648-9kxwkcbl	259	15	severe	severe	JJ
cord-277648-9kxwkcbl	259	16	and	and	CC
cord-277648-9kxwkcbl	259	17	3	3	CD
cord-277648-9kxwkcbl	259	18	moderate	moderate	JJ
cord-277648-9kxwkcbl	259	19	)	)	-RRB-
cord-277648-9kxwkcbl	259	20	,	,	,
cord-277648-9kxwkcbl	259	21	and	and	CC
cord-277648-9kxwkcbl	259	22	3	3	CD
cord-277648-9kxwkcbl	259	23	healthy	healthy	JJ
cord-277648-9kxwkcbl	259	24	control	control	NN
cord-277648-9kxwkcbl	259	25	subjects	subject	NNS
cord-277648-9kxwkcbl	259	26	were	be	VBD
cord-277648-9kxwkcbl	259	27	obtained	obtain	VBN
cord-277648-9kxwkcbl	259	28	from	from	IN
cord-277648-9kxwkcbl	259	29	the	the	DT
cord-277648-9kxwkcbl	259	30	GEO	GEO	NNP
cord-277648-9kxwkcbl	259	31	under	under	IN
cord-277648-9kxwkcbl	259	32	accession	accession	NN
cord-277648-9kxwkcbl	259	33	number	number	NN
cord-277648-9kxwkcbl	259	34	GSE145926	GSE145926	NNPS
cord-277648-9kxwkcbl	259	35	.	.	.
cord-277648-9kxwkcbl	260	1	[	[	-LRB-
cord-277648-9kxwkcbl	260	2	27	27	CD
cord-277648-9kxwkcbl	260	3	]	]	-RRB-
cord-277648-9kxwkcbl	260	4	ScRNA	ScRNA	NNP
cord-277648-9kxwkcbl	260	5	-	-	HYPH
cord-277648-9kxwkcbl	260	6	seq	seq	NN
cord-277648-9kxwkcbl	260	7	data	datum	NNS
cord-277648-9kxwkcbl	260	8	from	from	IN
cord-277648-9kxwkcbl	260	9	an	an	DT
cord-277648-9kxwkcbl	260	10	additional	additional	JJ
cord-277648-9kxwkcbl	260	11	healthy	healthy	JJ
cord-277648-9kxwkcbl	260	12	BALF	BALF	NNP
cord-277648-9kxwkcbl	260	13	donor	donor	NN
cord-277648-9kxwkcbl	260	14	was	be	VBD
cord-277648-9kxwkcbl	260	15	obtained	obtain	VBN
cord-277648-9kxwkcbl	260	16	from	from	IN
cord-277648-9kxwkcbl	260	17	the	the	DT
cord-277648-9kxwkcbl	260	18	GEO	GEO	NNP
cord-277648-9kxwkcbl	260	19	under	under	IN
cord-277648-9kxwkcbl	260	20	accession	accession	NN
cord-277648-9kxwkcbl	260	21	number	number	NN
cord-277648-9kxwkcbl	260	22	GSM3660650	GSM3660650	NNP
cord-277648-9kxwkcbl	260	23	.	.	.
cord-277648-9kxwkcbl	261	1	[	[	-LRB-
cord-277648-9kxwkcbl	261	2	27	27	CD
cord-277648-9kxwkcbl	261	3	,	,	,
cord-277648-9kxwkcbl	261	4	64	64	CD
cord-277648-9kxwkcbl	261	5	]	]	-RRB-
cord-277648-9kxwkcbl	261	6	Severity	severity	NN
cord-277648-9kxwkcbl	261	7	-	-	HYPH
cord-277648-9kxwkcbl	261	8	level	level	NN
cord-277648-9kxwkcbl	261	9	stratifications	stratification	NNS
cord-277648-9kxwkcbl	261	10	for	for	IN
cord-277648-9kxwkcbl	261	11	BALF	BALF	NNP
cord-277648-9kxwkcbl	261	12	donors	donor	NNS
cord-277648-9kxwkcbl	261	13	(	(	-LRB-
cord-277648-9kxwkcbl	261	14	severe	severe	JJ
cord-277648-9kxwkcbl	261	15	/	/	SYM
cord-277648-9kxwkcbl	261	16	moderate	moderate	JJ
cord-277648-9kxwkcbl	261	17	/	/	SYM
cord-277648-9kxwkcbl	261	18	healthy	healthy	JJ
cord-277648-9kxwkcbl	261	19	)	)	-RRB-
cord-277648-9kxwkcbl	261	20	were	be	VBD
cord-277648-9kxwkcbl	261	21	used	use	VBN
cord-277648-9kxwkcbl	261	22	exactly	exactly	RB
cord-277648-9kxwkcbl	261	23	as	as	IN
cord-277648-9kxwkcbl	261	24	provided	provide	VBN
cord-277648-9kxwkcbl	261	25	in	in	IN
cord-277648-9kxwkcbl	261	26	the	the	DT
cord-277648-9kxwkcbl	261	27	original	original	JJ
cord-277648-9kxwkcbl	261	28	manuscript	manuscript	NN
cord-277648-9kxwkcbl	261	29	.	.	.
cord-277648-9kxwkcbl	262	1	5	5	CD
cord-277648-9kxwkcbl	262	2	out	out	IN
cord-277648-9kxwkcbl	262	3	of	of	IN
cord-277648-9kxwkcbl	262	4	6	6	CD
cord-277648-9kxwkcbl	262	5	severe	severe	JJ
cord-277648-9kxwkcbl	262	6	BALF	BALF	NNP
cord-277648-9kxwkcbl	262	7	donors	donor	NNS
cord-277648-9kxwkcbl	262	8	were	be	VBD
cord-277648-9kxwkcbl	262	9	invasively	invasively	RB
cord-277648-9kxwkcbl	262	10	ventilated	ventilate	VBN
cord-277648-9kxwkcbl	262	11	,	,	,
cord-277648-9kxwkcbl	262	12	with	with	IN
cord-277648-9kxwkcbl	262	13	the	the	DT
cord-277648-9kxwkcbl	262	14	exception	exception	NN
cord-277648-9kxwkcbl	262	15	of	of	IN
cord-277648-9kxwkcbl	262	16	S1	S1	NNP
cord-277648-9kxwkcbl	262	17	.	.	.
cord-277648-9kxwkcbl	262	18	 	 	_SP
cord-277648-9kxwkcbl	263	1	Gene	gene	NN
cord-277648-9kxwkcbl	263	2	-	-	HYPH
cord-277648-9kxwkcbl	263	3	barcode	barcode	NN
cord-277648-9kxwkcbl	263	4	matrices	matrix	NNS
cord-277648-9kxwkcbl	263	5	obtained	obtain	VBN
cord-277648-9kxwkcbl	263	6	from	from	IN
cord-277648-9kxwkcbl	263	7	the	the	DT
cord-277648-9kxwkcbl	263	8	GEO	GEO	NNP
cord-277648-9kxwkcbl	263	9	were	be	VBD
cord-277648-9kxwkcbl	263	10	preprocessed	preprocesse	VBN
cord-277648-9kxwkcbl	263	11	using	use	VBG
cord-277648-9kxwkcbl	263	12	Seurat	Seurat	NNP
cord-277648-9kxwkcbl	263	13	(	(	-LRB-
cord-277648-9kxwkcbl	263	14	v.	v.	IN
cord-277648-9kxwkcbl	263	15	3.1.5	3.1.5	CD
cord-277648-9kxwkcbl	263	16	)	)	-RRB-
cord-277648-9kxwkcbl	263	17	in	in	IN
cord-277648-9kxwkcbl	263	18	R	R	NNP
cord-277648-9kxwkcbl	263	19	(	(	-LRB-
cord-277648-9kxwkcbl	263	20	v.	v.	IN
cord-277648-9kxwkcbl	263	21	4.0.0	4.0.0	CD
cord-277648-9kxwkcbl	263	22	)	)	-RRB-
cord-277648-9kxwkcbl	263	23	.	.	.
cord-277648-9kxwkcbl	264	1	Matrices	matrix	NNS
cord-277648-9kxwkcbl	264	2	were	be	VBD
cord-277648-9kxwkcbl	264	3	filtered	filter	VBN
cord-277648-9kxwkcbl	264	4	to	to	TO
cord-277648-9kxwkcbl	264	5	preserve	preserve	VB
cord-277648-9kxwkcbl	264	6	cells	cell	NNS
cord-277648-9kxwkcbl	264	7	with	with	IN
cord-277648-9kxwkcbl	264	8	a	a	DT
cord-277648-9kxwkcbl	264	9	UMI	UMI	NNP
cord-277648-9kxwkcbl	264	10	count	count	NN
cord-277648-9kxwkcbl	264	11	over	over	IN
cord-277648-9kxwkcbl	264	12	1,000	1,000	CD
cord-277648-9kxwkcbl	264	13	,	,	,
cord-277648-9kxwkcbl	264	14	gene	gene	NN
cord-277648-9kxwkcbl	264	15	count	count	NN
cord-277648-9kxwkcbl	264	16	between	between	IN
cord-277648-9kxwkcbl	264	17	200	200	CD
cord-277648-9kxwkcbl	264	18	and	and	CC
cord-277648-9kxwkcbl	264	19	6,000	6,000	CD
cord-277648-9kxwkcbl	264	20	,	,	,
cord-277648-9kxwkcbl	264	21	and	and	CC
cord-277648-9kxwkcbl	264	22	expression	expression	NN
cord-277648-9kxwkcbl	264	23	of	of	IN
cord-277648-9kxwkcbl	264	24	less	less	JJR
cord-277648-9kxwkcbl	264	25	than	than	IN
cord-277648-9kxwkcbl	264	26	10	10	CD
cord-277648-9kxwkcbl	264	27	%	%	NN
cord-277648-9kxwkcbl	264	28	mitochondrial	mitochondrial	JJ
cord-277648-9kxwkcbl	264	29	RNA	RNA	NNP
cord-277648-9kxwkcbl	264	30	.	.	.
cord-277648-9kxwkcbl	265	1	For	for	IN
cord-277648-9kxwkcbl	265	2	PBMC	PBMC	NNP
cord-277648-9kxwkcbl	265	3	data	datum	NNS
cord-277648-9kxwkcbl	265	4	,	,	,
cord-277648-9kxwkcbl	265	5	cells	cell	NNS
cord-277648-9kxwkcbl	265	6	were	be	VBD
cord-277648-9kxwkcbl	265	7	additionally	additionally	RB
cord-277648-9kxwkcbl	265	8	filtered	filter	VBN
cord-277648-9kxwkcbl	265	9	to	to	TO
cord-277648-9kxwkcbl	265	10	preserve	preserve	VB
cord-277648-9kxwkcbl	265	11	cells	cell	NNS
cord-277648-9kxwkcbl	265	12	expressing	express	VBG
cord-277648-9kxwkcbl	265	13	less	less	JJR
cord-277648-9kxwkcbl	265	14	than	than	IN
cord-277648-9kxwkcbl	265	15	20	20	CD
cord-277648-9kxwkcbl	265	16	%	%	NN
cord-277648-9kxwkcbl	265	17	18S	18S	NNP
cord-277648-9kxwkcbl	265	18	RNA	RNA	NNP
cord-277648-9kxwkcbl	265	19	and	and	CC
cord-277648-9kxwkcbl	265	20	less	less	JJR
cord-277648-9kxwkcbl	265	21	than	than	IN
cord-277648-9kxwkcbl	265	22	20	20	CD
cord-277648-9kxwkcbl	265	23	%	%	NN
cord-277648-9kxwkcbl	265	24	28S	28S	NNP
cord-277648-9kxwkcbl	265	25	RNA	RNA	NNP
cord-277648-9kxwkcbl	265	26	.	.	.
cord-277648-9kxwkcbl	266	1	Gene	gene	NN
cord-277648-9kxwkcbl	266	2	-	-	HYPH
cord-277648-9kxwkcbl	266	3	barcode	barcode	NN
cord-277648-9kxwkcbl	266	4	matrices	matrix	NNS
cord-277648-9kxwkcbl	266	5	unique	unique	JJ
cord-277648-9kxwkcbl	266	6	to	to	IN
cord-277648-9kxwkcbl	266	7	each	each	DT
cord-277648-9kxwkcbl	266	8	donor	donor	NN
cord-277648-9kxwkcbl	266	9	were	be	VBD
cord-277648-9kxwkcbl	266	10	subsequently	subsequently	RB
cord-277648-9kxwkcbl	266	11	normalized	normalize	VBN
cord-277648-9kxwkcbl	266	12	using	use	VBG
cord-277648-9kxwkcbl	266	13	the	the	DT
cord-277648-9kxwkcbl	266	14	'	'	``
cord-277648-9kxwkcbl	266	15	NormalizeData	NormalizeData	NNP
cord-277648-9kxwkcbl	266	16	'	'	POS
cord-277648-9kxwkcbl	266	17	function	function	NN
cord-277648-9kxwkcbl	266	18	and	and	CC
cord-277648-9kxwkcbl	266	19	the	the	DT
cord-277648-9kxwkcbl	266	20	2,000	2,000	CD
cord-277648-9kxwkcbl	266	21	most	most	RBS
cord-277648-9kxwkcbl	266	22	highly	highly	RB
cord-277648-9kxwkcbl	266	23	variable	variable	JJ
cord-277648-9kxwkcbl	266	24	genes	gene	NNS
cord-277648-9kxwkcbl	266	25	(	(	-LRB-
cord-277648-9kxwkcbl	266	26	features	feature	NNS
cord-277648-9kxwkcbl	266	27	)	)	-RRB-
cord-277648-9kxwkcbl	266	28	were	be	VBD
cord-277648-9kxwkcbl	266	29	identified	identify	VBN
cord-277648-9kxwkcbl	266	30	via	via	IN
cord-277648-9kxwkcbl	266	31	the	the	DT
cord-277648-9kxwkcbl	266	32	'	'	``
cord-277648-9kxwkcbl	266	33	FindVariableFeatures	findvariablefeature	NNS
cord-277648-9kxwkcbl	266	34	'	'	POS
cord-277648-9kxwkcbl	266	35	function	function	NN
cord-277648-9kxwkcbl	266	36	using	use	VBG
cord-277648-9kxwkcbl	266	37	a	a	DT
cord-277648-9kxwkcbl	266	38	variance	variance	NN
cord-277648-9kxwkcbl	266	39	stabilizing	stabilize	VBG
cord-277648-9kxwkcbl	266	40	transformation	transformation	NN
cord-277648-9kxwkcbl	266	41	.	.	.
cord-277648-9kxwkcbl	267	1	Individual	individual	JJ
cord-277648-9kxwkcbl	267	2	donor	donor	NN
cord-277648-9kxwkcbl	267	3	datasets	dataset	NNS
cord-277648-9kxwkcbl	267	4	were	be	VBD
cord-277648-9kxwkcbl	267	5	subsequently	subsequently	RB
cord-277648-9kxwkcbl	267	6	aligned	align	VBN
cord-277648-9kxwkcbl	267	7	and	and	CC
cord-277648-9kxwkcbl	267	8	integrated	integrate	VBN
cord-277648-9kxwkcbl	267	9	using	use	VBG
cord-277648-9kxwkcbl	267	10	the	the	DT
cord-277648-9kxwkcbl	267	11	standard	standard	JJ
cord-277648-9kxwkcbl	267	12	Seurat	Seurat	NNP
cord-277648-9kxwkcbl	267	13	v3	v3	NNP
cord-277648-9kxwkcbl	267	14	multi	multi	JJ
cord-277648-9kxwkcbl	267	15	-	-	JJ
cord-277648-9kxwkcbl	267	16	donor	donor	JJ
cord-277648-9kxwkcbl	267	17	integration	integration	NN
cord-277648-9kxwkcbl	267	18	workflow	workflow	NN
cord-277648-9kxwkcbl	267	19	,	,	,
cord-277648-9kxwkcbl	267	20	finding	find	VBG
cord-277648-9kxwkcbl	267	21	pairwise	pairwise	JJ
cord-277648-9kxwkcbl	267	22	anchors	anchor	NNS
cord-277648-9kxwkcbl	267	23	using	use	VBG
cord-277648-9kxwkcbl	267	24	the	the	DT
cord-277648-9kxwkcbl	267	25	'	'	``
cord-277648-9kxwkcbl	267	26	FindIntegrationAnchors	findintegrationanchor	NNS
cord-277648-9kxwkcbl	267	27	'	'	POS
cord-277648-9kxwkcbl	267	28	function	function	NN
cord-277648-9kxwkcbl	267	29	acting	act	VBG
cord-277648-9kxwkcbl	267	30	on	on	IN
cord-277648-9kxwkcbl	267	31	50	50	CD
cord-277648-9kxwkcbl	267	32	dimensions	dimension	NNS
cord-277648-9kxwkcbl	267	33	with	with	IN
cord-277648-9kxwkcbl	267	34	default	default	NN
cord-277648-9kxwkcbl	267	35	parameters	parameter	NNS
cord-277648-9kxwkcbl	267	36	(	(	-LRB-
cord-277648-9kxwkcbl	267	37	k.filter=200	k.filter=200	NNP
cord-277648-9kxwkcbl	267	38	)	)	-RRB-
cord-277648-9kxwkcbl	267	39	,	,	,
cord-277648-9kxwkcbl	267	40	then	then	RB
cord-277648-9kxwkcbl	267	41	applying	apply	VBG
cord-277648-9kxwkcbl	267	42	the	the	DT
cord-277648-9kxwkcbl	267	43	'	'	``
cord-277648-9kxwkcbl	267	44	IntegrateData	IntegrateData	NNP
cord-277648-9kxwkcbl	267	45	'	'	POS
cord-277648-9kxwkcbl	267	46	function	function	NN
cord-277648-9kxwkcbl	267	47	on	on	IN
cord-277648-9kxwkcbl	267	48	50	50	CD
cord-277648-9kxwkcbl	267	49	dimensions	dimension	NNS
cord-277648-9kxwkcbl	267	50	.	.	.
cord-277648-9kxwkcbl	268	1	Multi	multi	JJ
cord-277648-9kxwkcbl	268	2	-	-	JJ
cord-277648-9kxwkcbl	268	3	donor	donor	NN
cord-277648-9kxwkcbl	268	4	integration	integration	NN
cord-277648-9kxwkcbl	268	5	and	and	CC
cord-277648-9kxwkcbl	268	6	all	all	DT
cord-277648-9kxwkcbl	268	7	further	further	JJ
cord-277648-9kxwkcbl	268	8	analyses	analysis	NNS
cord-277648-9kxwkcbl	268	9	were	be	VBD
cord-277648-9kxwkcbl	268	10	performed	perform	VBN
cord-277648-9kxwkcbl	268	11	separately	separately	RB
cord-277648-9kxwkcbl	268	12	on	on	IN
cord-277648-9kxwkcbl	268	13	BALF	BALF	NNP
cord-277648-9kxwkcbl	268	14	and	and	CC
cord-277648-9kxwkcbl	268	15	PBMC	PBMC	NNP
cord-277648-9kxwkcbl	268	16	datasets	dataset	NNS
cord-277648-9kxwkcbl	268	17	.	.	.
cord-277648-9kxwkcbl	269	1	Following	follow	VBG
cord-277648-9kxwkcbl	269	2	integration	integration	NN
cord-277648-9kxwkcbl	269	3	,	,	,
cord-277648-9kxwkcbl	269	4	"	"	``
cord-277648-9kxwkcbl	269	5	raw	raw	JJ
cord-277648-9kxwkcbl	269	6	"	"	''
cord-277648-9kxwkcbl	269	7	RNA	rna	NN
cord-277648-9kxwkcbl	269	8	expression	expression	NN
cord-277648-9kxwkcbl	269	9	values	value	NNS
cord-277648-9kxwkcbl	269	10	were	be	VBD
cord-277648-9kxwkcbl	269	11	normalized	normalize	VBN
cord-277648-9kxwkcbl	269	12	using	use	VBG
cord-277648-9kxwkcbl	269	13	log	log	NN
cord-277648-9kxwkcbl	269	14	-	-	HYPH
cord-277648-9kxwkcbl	269	15	normalization	normalization	NN
cord-277648-9kxwkcbl	269	16	via	via	IN
cord-277648-9kxwkcbl	269	17	the	the	DT
cord-277648-9kxwkcbl	269	18	'	'	``
cord-277648-9kxwkcbl	269	19	NormalizeData	NormalizeData	NNP
cord-277648-9kxwkcbl	269	20	'	'	POS
cord-277648-9kxwkcbl	269	21	function	function	NN
cord-277648-9kxwkcbl	269	22	and	and	CC
cord-277648-9kxwkcbl	269	23	the	the	DT
cord-277648-9kxwkcbl	269	24	2,000	2,000	CD
cord-277648-9kxwkcbl	269	25	most	most	RBS
cord-277648-9kxwkcbl	269	26	variable	variable	JJ
cord-277648-9kxwkcbl	269	27	features	feature	NNS
cord-277648-9kxwkcbl	269	28	were	be	VBD
cord-277648-9kxwkcbl	269	29	identified	identify	VBN
cord-277648-9kxwkcbl	269	30	using	use	VBG
cord-277648-9kxwkcbl	269	31	'	'	``
cord-277648-9kxwkcbl	269	32	FindVariableFeatures	findvariablefeature	NNS
cord-277648-9kxwkcbl	269	33	'	'	''
cord-277648-9kxwkcbl	269	34	.	.	.
cord-277648-9kxwkcbl	270	1	Raw	raw	JJ
cord-277648-9kxwkcbl	270	2	expression	expression	NN
cord-277648-9kxwkcbl	270	3	levels	level	NNS
cord-277648-9kxwkcbl	270	4	were	be	VBD
cord-277648-9kxwkcbl	270	5	left	leave	VBN
cord-277648-9kxwkcbl	270	6	unscaled	unscaled	JJ
cord-277648-9kxwkcbl	270	7	so	so	IN
cord-277648-9kxwkcbl	270	8	that	that	IN
cord-277648-9kxwkcbl	270	9	scaling	scaling	NN
cord-277648-9kxwkcbl	270	10	could	could	MD
cord-277648-9kxwkcbl	270	11	later	later	RB
cord-277648-9kxwkcbl	270	12	be	be	VB
cord-277648-9kxwkcbl	270	13	applied	apply	VBN
cord-277648-9kxwkcbl	270	14	as	as	IN
cord-277648-9kxwkcbl	270	15	needed	need	VBN
cord-277648-9kxwkcbl	270	16	(	(	-LRB-
cord-277648-9kxwkcbl	270	17	e.g.	e.g.	RB
cord-277648-9kxwkcbl	270	18	for	for	IN
cord-277648-9kxwkcbl	270	19	generating	generate	VBG
cord-277648-9kxwkcbl	270	20	marker	marker	NN
cord-277648-9kxwkcbl	270	21	gene	gene	NN
cord-277648-9kxwkcbl	270	22	heatmaps	heatmaps	NNP
cord-277648-9kxwkcbl	270	23	)	)	-RRB-
cord-277648-9kxwkcbl	270	24	.	.	.
cord-277648-9kxwkcbl	271	1	In	in	IN
cord-277648-9kxwkcbl	271	2	parallel	parallel	NN
cord-277648-9kxwkcbl	271	3	,	,	,
cord-277648-9kxwkcbl	271	4	"	"	''
cord-277648-9kxwkcbl	271	5	integrated	integrated	JJ
cord-277648-9kxwkcbl	271	6	"	"	''
cord-277648-9kxwkcbl	271	7	expression	expression	NN
cord-277648-9kxwkcbl	271	8	values	value	NNS
cord-277648-9kxwkcbl	271	9	were	be	VBD
cord-277648-9kxwkcbl	271	10	scaled	scale	VBN
cord-277648-9kxwkcbl	271	11	using	use	VBG
cord-277648-9kxwkcbl	271	12	the	the	DT
cord-277648-9kxwkcbl	271	13	'	'	``
cord-277648-9kxwkcbl	271	14	ScaleData	ScaleData	NNP
cord-277648-9kxwkcbl	271	15	'	'	POS
cord-277648-9kxwkcbl	271	16	function	function	NN
cord-277648-9kxwkcbl	271	17	,	,	,
cord-277648-9kxwkcbl	271	18	regressing	regress	VBG
cord-277648-9kxwkcbl	271	19	out	out	RP
cord-277648-9kxwkcbl	271	20	UMI	UMI	NNP
cord-277648-9kxwkcbl	271	21	count	count	NN
cord-277648-9kxwkcbl	271	22	,	,	,
cord-277648-9kxwkcbl	271	23	number	number	NN
cord-277648-9kxwkcbl	271	24	of	of	IN
cord-277648-9kxwkcbl	271	25	genes	gene	NNS
cord-277648-9kxwkcbl	271	26	,	,	,
cord-277648-9kxwkcbl	271	27	and	and	CC
cord-277648-9kxwkcbl	271	28	percent	percent	NN
cord-277648-9kxwkcbl	271	29	rRNA	rRNA	NNP
cord-277648-9kxwkcbl	271	30	.	.	.
cord-277648-9kxwkcbl	272	1	PBMC	PBMC	NNP
cord-277648-9kxwkcbl	272	2	data	datum	NNS
cord-277648-9kxwkcbl	272	3	contained	contain	VBD
cord-277648-9kxwkcbl	272	4	rRNA	rRNA	NNP
cord-277648-9kxwkcbl	272	5	transcripts	transcript	NNS
cord-277648-9kxwkcbl	272	6	to	to	TO
cord-277648-9kxwkcbl	272	7	regress	regress	VB
cord-277648-9kxwkcbl	272	8	,	,	,
cord-277648-9kxwkcbl	272	9	whereas	whereas	IN
cord-277648-9kxwkcbl	272	10	BALF	BALF	NNP
cord-277648-9kxwkcbl	272	11	data	datum	NNS
cord-277648-9kxwkcbl	272	12	did	do	VBD
cord-277648-9kxwkcbl	272	13	not	not	RB
cord-277648-9kxwkcbl	272	14	.	.	.
cord-277648-9kxwkcbl	273	1	Dimensionality	Dimensionality	NNP
cord-277648-9kxwkcbl	273	2	reduction	reduction	NN
cord-277648-9kxwkcbl	273	3	via	via	IN
cord-277648-9kxwkcbl	273	4	principal	principal	JJ
cord-277648-9kxwkcbl	273	5	component	component	NN
cord-277648-9kxwkcbl	273	6	analysis	analysis	NN
cord-277648-9kxwkcbl	273	7	(	(	-LRB-
cord-277648-9kxwkcbl	273	8	PCA	PCA	NNP
cord-277648-9kxwkcbl	273	9	)	)	-RRB-
cord-277648-9kxwkcbl	273	10	was	be	VBD
cord-277648-9kxwkcbl	273	11	carried	carry	VBN
cord-277648-9kxwkcbl	273	12	out	out	RP
cord-277648-9kxwkcbl	273	13	using	use	VBG
cord-277648-9kxwkcbl	273	14	the	the	DT
cord-277648-9kxwkcbl	273	15	'	'	``
cord-277648-9kxwkcbl	273	16	RunPCA	RunPCA	NNP
cord-277648-9kxwkcbl	273	17	'	'	POS
cord-277648-9kxwkcbl	273	18	function	function	NN
cord-277648-9kxwkcbl	273	19	and	and	CC
cord-277648-9kxwkcbl	273	20	the	the	DT
cord-277648-9kxwkcbl	273	21	first	first	JJ
cord-277648-9kxwkcbl	273	22	100	100	CD
cord-277648-9kxwkcbl	273	23	principal	principal	JJ
cord-277648-9kxwkcbl	273	24	components	component	NNS
cord-277648-9kxwkcbl	273	25	were	be	VBD
cord-277648-9kxwkcbl	273	26	retained	retain	VBN
cord-277648-9kxwkcbl	273	27	.	.	.
cord-277648-9kxwkcbl	274	1	This	this	DT
cord-277648-9kxwkcbl	274	2	reduction	reduction	NN
cord-277648-9kxwkcbl	274	3	was	be	VBD
cord-277648-9kxwkcbl	274	4	projected	project	VBN
cord-277648-9kxwkcbl	274	5	onto	onto	IN
cord-277648-9kxwkcbl	274	6	the	the	DT
cord-277648-9kxwkcbl	274	7	entire	entire	JJ
cord-277648-9kxwkcbl	274	8	dataset	dataset	NN
cord-277648-9kxwkcbl	274	9	prior	prior	RB
cord-277648-9kxwkcbl	274	10	to	to	IN
cord-277648-9kxwkcbl	274	11	clustering	clustering	NN
cord-277648-9kxwkcbl	274	12	.	.	.
cord-277648-9kxwkcbl	275	1	Clustering	clustering	NN
cord-277648-9kxwkcbl	275	2	was	be	VBD
cord-277648-9kxwkcbl	275	3	performed	perform	VBN
cord-277648-9kxwkcbl	275	4	by	by	IN
cord-277648-9kxwkcbl	275	5	finding	find	VBG
cord-277648-9kxwkcbl	275	6	nearest	near	JJS
cord-277648-9kxwkcbl	275	7	neighbors	neighbor	NNS
cord-277648-9kxwkcbl	275	8	using	use	VBG
cord-277648-9kxwkcbl	275	9	the	the	DT
cord-277648-9kxwkcbl	275	10	'	'	``
cord-277648-9kxwkcbl	275	11	FindNeighbors	FindNeighbors	NNP
cord-277648-9kxwkcbl	275	12	'	'	POS
cord-277648-9kxwkcbl	275	13	function	function	NN
cord-277648-9kxwkcbl	275	14	in	in	IN
cord-277648-9kxwkcbl	275	15	Seurat	Seurat	NNP
cord-277648-9kxwkcbl	275	16	acting	act	VBG
cord-277648-9kxwkcbl	275	17	on	on	IN
cord-277648-9kxwkcbl	275	18	50	50	CD
cord-277648-9kxwkcbl	275	19	dimensions	dimension	NNS
cord-277648-9kxwkcbl	275	20	,	,	,
cord-277648-9kxwkcbl	275	21	then	then	RB
cord-277648-9kxwkcbl	275	22	running	run	VBG
cord-277648-9kxwkcbl	275	23	the	the	DT
cord-277648-9kxwkcbl	275	24	Louvain	Louvain	NNP
cord-277648-9kxwkcbl	275	25	algorithm	algorithm	NN
cord-277648-9kxwkcbl	275	26	via	via	IN
cord-277648-9kxwkcbl	275	27	the	the	DT
cord-277648-9kxwkcbl	275	28	'	'	``
cord-277648-9kxwkcbl	275	29	FindClusters	FindClusters	NNP
cord-277648-9kxwkcbl	275	30	'	'	POS
cord-277648-9kxwkcbl	275	31	function	function	NN
cord-277648-9kxwkcbl	275	32	with	with	IN
cord-277648-9kxwkcbl	275	33	a	a	DT
cord-277648-9kxwkcbl	275	34	resolution	resolution	NN
cord-277648-9kxwkcbl	275	35	parameter	parameter	NN
cord-277648-9kxwkcbl	275	36	of	of	IN
cord-277648-9kxwkcbl	275	37	1.4	1.4	CD
cord-277648-9kxwkcbl	275	38	.	.	.
cord-277648-9kxwkcbl	276	1	The	the	DT
cord-277648-9kxwkcbl	276	2	resulting	result	VBG
cord-277648-9kxwkcbl	276	3	clustered	cluster	VBN
cord-277648-9kxwkcbl	276	4	datasets	dataset	NNS
cord-277648-9kxwkcbl	276	5	for	for	IN
cord-277648-9kxwkcbl	276	6	BALF	BALF	NNP
cord-277648-9kxwkcbl	276	7	and	and	CC
cord-277648-9kxwkcbl	276	8	PBMC	PBMC	NNP
cord-277648-9kxwkcbl	276	9	were	be	VBD
cord-277648-9kxwkcbl	276	10	separately	separately	RB
cord-277648-9kxwkcbl	276	11	visualized	visualize	VBN
cord-277648-9kxwkcbl	276	12	by	by	IN
cord-277648-9kxwkcbl	276	13	uniform	uniform	JJ
cord-277648-9kxwkcbl	276	14	manifold	manifold	JJ
cord-277648-9kxwkcbl	276	15	approximation	approximation	NN
cord-277648-9kxwkcbl	276	16	and	and	CC
cord-277648-9kxwkcbl	276	17	projection	projection	NN
cord-277648-9kxwkcbl	276	18	(	(	-LRB-
cord-277648-9kxwkcbl	276	19	UMAP	UMAP	NNP
cord-277648-9kxwkcbl	276	20	)	)	-RRB-
cord-277648-9kxwkcbl	276	21	acting	act	VBG
cord-277648-9kxwkcbl	276	22	on	on	IN
cord-277648-9kxwkcbl	276	23	the	the	DT
cord-277648-9kxwkcbl	276	24	first	first	JJ
cord-277648-9kxwkcbl	276	25	50	50	CD
cord-277648-9kxwkcbl	276	26	principal	principal	JJ
cord-277648-9kxwkcbl	276	27	components	component	NNS
cord-277648-9kxwkcbl	276	28	.	.	.
cord-277648-9kxwkcbl	277	1	Cell	cell	NN
cord-277648-9kxwkcbl	277	2	type	type	NN
cord-277648-9kxwkcbl	277	3	annotation	annotation	NN
cord-277648-9kxwkcbl	277	4	was	be	VBD
cord-277648-9kxwkcbl	277	5	conducted	conduct	VBN
cord-277648-9kxwkcbl	277	6	using	use	VBG
cord-277648-9kxwkcbl	277	7	the	the	DT
cord-277648-9kxwkcbl	277	8	resultant	resultant	JJ
cord-277648-9kxwkcbl	277	9	clusters	cluster	NNS
cord-277648-9kxwkcbl	277	10	for	for	IN
cord-277648-9kxwkcbl	277	11	BALF	BALF	NNP
cord-277648-9kxwkcbl	277	12	and	and	CC
cord-277648-9kxwkcbl	277	13	PBMC	PBMC	NNP
cord-277648-9kxwkcbl	277	14	data	datum	NNS
cord-277648-9kxwkcbl	277	15	.	.	.
cord-277648-9kxwkcbl	278	1	Clusters	cluster	NNS
cord-277648-9kxwkcbl	278	2	were	be	VBD
cord-277648-9kxwkcbl	278	3	annotated	annotate	VBN
cord-277648-9kxwkcbl	278	4	according	accord	VBG
cord-277648-9kxwkcbl	278	5	to	to	IN
cord-277648-9kxwkcbl	278	6	the	the	DT
cord-277648-9kxwkcbl	278	7	average	average	JJ
cord-277648-9kxwkcbl	278	8	expression	expression	NN
cord-277648-9kxwkcbl	278	9	levels	level	NNS
cord-277648-9kxwkcbl	278	10	of	of	IN
cord-277648-9kxwkcbl	278	11	canonical	canonical	JJ
cord-277648-9kxwkcbl	278	12	marker	marker	NN
cord-277648-9kxwkcbl	278	13	genes	gene	NNS
cord-277648-9kxwkcbl	278	14	identified	identify	VBN
cord-277648-9kxwkcbl	278	15	in	in	IN
cord-277648-9kxwkcbl	278	16	the	the	DT
cord-277648-9kxwkcbl	278	17	original	original	JJ
cord-277648-9kxwkcbl	278	18	papers	paper	NNS
cord-277648-9kxwkcbl	278	19	for	for	IN
cord-277648-9kxwkcbl	278	20	the	the	DT
cord-277648-9kxwkcbl	278	21	BALF	BALF	NNP
cord-277648-9kxwkcbl	278	22	and	and	CC
cord-277648-9kxwkcbl	278	23	PBMC	PBMC	NNP
cord-277648-9kxwkcbl	278	24	datasets	dataset	NNS
cord-277648-9kxwkcbl	278	25	[	[	-LRB-
cord-277648-9kxwkcbl	278	26	27	27	CD
cord-277648-9kxwkcbl	278	27	,	,	,
cord-277648-9kxwkcbl	278	28	32	32	CD
cord-277648-9kxwkcbl	278	29	]	]	-RRB-
cord-277648-9kxwkcbl	278	30	,	,	,
cord-277648-9kxwkcbl	278	31	the	the	DT
cord-277648-9kxwkcbl	278	32	broader	broad	JJR
cord-277648-9kxwkcbl	278	33	literature	literature	NN
cord-277648-9kxwkcbl	278	34	,	,	,
cord-277648-9kxwkcbl	278	35	and	and	CC
cord-277648-9kxwkcbl	278	36	the	the	DT
cord-277648-9kxwkcbl	278	37	Human	Human	NNP
cord-277648-9kxwkcbl	278	38	Protein	Protein	NNP
cord-277648-9kxwkcbl	278	39	Atlas	Atlas	NNP
cord-277648-9kxwkcbl	278	40	[	[	-LRB-
cord-277648-9kxwkcbl	278	41	65	65	CD
cord-277648-9kxwkcbl	278	42	]	]	-RRB-
cord-277648-9kxwkcbl	278	43	.	.	.
cord-277648-9kxwkcbl	279	1	Clusters	cluster	NNS
cord-277648-9kxwkcbl	279	2	deemed	deem	VBD
cord-277648-9kxwkcbl	279	3	identical	identical	JJ
cord-277648-9kxwkcbl	279	4	by	by	IN
cord-277648-9kxwkcbl	279	5	similar	similar	JJ
cord-277648-9kxwkcbl	279	6	presence	presence	NN
cord-277648-9kxwkcbl	279	7	of	of	IN
cord-277648-9kxwkcbl	279	8	marker	marker	NN
cord-277648-9kxwkcbl	279	9	genes	gene	NNS
cord-277648-9kxwkcbl	279	10	were	be	VBD
cord-277648-9kxwkcbl	279	11	merged	merge	VBN
cord-277648-9kxwkcbl	279	12	during	during	IN
cord-277648-9kxwkcbl	279	13	annotation	annotation	NN
cord-277648-9kxwkcbl	279	14	.	.	.
cord-277648-9kxwkcbl	280	1	A	a	DT
cord-277648-9kxwkcbl	280	2	list	list	NN
cord-277648-9kxwkcbl	280	3	of	of	IN
cord-277648-9kxwkcbl	280	4	the	the	DT
cord-277648-9kxwkcbl	280	5	marker	marker	NN
cord-277648-9kxwkcbl	280	6	genes	gene	NNS
cord-277648-9kxwkcbl	280	7	used	use	VBN
cord-277648-9kxwkcbl	280	8	for	for	IN
cord-277648-9kxwkcbl	280	9	cell	cell	NN
cord-277648-9kxwkcbl	280	10	type	type	NN
cord-277648-9kxwkcbl	280	11	annotation	annotation	NN
cord-277648-9kxwkcbl	280	12	is	be	VBZ
cord-277648-9kxwkcbl	280	13	available	available	JJ
cord-277648-9kxwkcbl	280	14	in	in	IN
cord-277648-9kxwkcbl	280	15	Supplemental	supplemental	JJ
cord-277648-9kxwkcbl	280	16	Figure	Figure	NNP
cord-277648-9kxwkcbl	280	17	S1	S1	NNP
cord-277648-9kxwkcbl	280	18	,	,	,
cord-277648-9kxwkcbl	280	19	along	along	IN
cord-277648-9kxwkcbl	280	20	with	with	IN
cord-277648-9kxwkcbl	280	21	a	a	DT
cord-277648-9kxwkcbl	280	22	visualization	visualization	NN
cord-277648-9kxwkcbl	280	23	of	of	IN
cord-277648-9kxwkcbl	280	24	expression	expression	NN
cord-277648-9kxwkcbl	280	25	levels	level	NNS
cord-277648-9kxwkcbl	280	26	.	.	.
cord-277648-9kxwkcbl	281	1	Following	follow	VBG
cord-277648-9kxwkcbl	281	2	cell	cell	NN
cord-277648-9kxwkcbl	281	3	type	type	NN
cord-277648-9kxwkcbl	281	4	annotation	annotation	NN
cord-277648-9kxwkcbl	281	5	for	for	IN
cord-277648-9kxwkcbl	281	6	the	the	DT
cord-277648-9kxwkcbl	281	7	BALF	BALF	NNP
cord-277648-9kxwkcbl	281	8	,	,	,
cord-277648-9kxwkcbl	281	9	populations	population	NNS
cord-277648-9kxwkcbl	281	10	annotated	annotate	VBN
cord-277648-9kxwkcbl	281	11	as	as	IN
cord-277648-9kxwkcbl	281	12	mononuclear	mononuclear	JJ
cord-277648-9kxwkcbl	281	13	phagocytes	phagocyte	NNS
cord-277648-9kxwkcbl	281	14	(	(	-LRB-
cord-277648-9kxwkcbl	281	15	consisting	consist	VBG
cord-277648-9kxwkcbl	281	16	of	of	IN
cord-277648-9kxwkcbl	281	17	one	one	CD
cord-277648-9kxwkcbl	281	18	merged	merge	VBN
cord-277648-9kxwkcbl	281	19	cluster	cluster	NN
cord-277648-9kxwkcbl	281	20	)	)	-RRB-
cord-277648-9kxwkcbl	281	21	and	and	CC
cord-277648-9kxwkcbl	281	22	T	T	NNP
cord-277648-9kxwkcbl	281	23	/	/	SYM
cord-277648-9kxwkcbl	281	24	NK	NK	NNP
cord-277648-9kxwkcbl	281	25	cells	cell	NNS
cord-277648-9kxwkcbl	281	26	(	(	-LRB-
cord-277648-9kxwkcbl	281	27	consisting	consist	VBG
cord-277648-9kxwkcbl	281	28	of	of	IN
cord-277648-9kxwkcbl	281	29	clusters	cluster	NNS
cord-277648-9kxwkcbl	281	30	annotated	annotate	VBN
cord-277648-9kxwkcbl	281	31	as	as	IN
cord-277648-9kxwkcbl	281	32	"	"	``
cord-277648-9kxwkcbl	281	33	NK	NK	NNP
cord-277648-9kxwkcbl	281	34	"	"	''
cord-277648-9kxwkcbl	281	35	,	,	,
cord-277648-9kxwkcbl	281	36	"	"	``
cord-277648-9kxwkcbl	281	37	Proliferating	proliferate	VBG
cord-277648-9kxwkcbl	281	38	T	t	NN
cord-277648-9kxwkcbl	281	39	"	"	''
cord-277648-9kxwkcbl	281	40	and	and	CC
cord-277648-9kxwkcbl	281	41	"	"	``
cord-277648-9kxwkcbl	281	42	Mixed	mixed	JJ
cord-277648-9kxwkcbl	281	43	T	t	NN
cord-277648-9kxwkcbl	281	44	"	"	''
cord-277648-9kxwkcbl	281	45	cells	cell	NNS
cord-277648-9kxwkcbl	281	46	)	)	-RRB-
cord-277648-9kxwkcbl	281	47	were	be	VBD
cord-277648-9kxwkcbl	281	48	separately	separately	RB
cord-277648-9kxwkcbl	281	49	re	re	VBN
cord-277648-9kxwkcbl	281	50	-	-	VBN
cord-277648-9kxwkcbl	281	51	integrated	integrate	VBN
cord-277648-9kxwkcbl	281	52	to	to	TO
cord-277648-9kxwkcbl	281	53	enable	enable	VB
cord-277648-9kxwkcbl	281	54	clustering	clustering	NN
cord-277648-9kxwkcbl	281	55	at	at	IN
cord-277648-9kxwkcbl	281	56	a	a	DT
cord-277648-9kxwkcbl	281	57	finer	fine	JJR
cord-277648-9kxwkcbl	281	58	resolution	resolution	NN
cord-277648-9kxwkcbl	281	59	.	.	.
cord-277648-9kxwkcbl	282	1	For	for	IN
cord-277648-9kxwkcbl	282	2	mononuclear	mononuclear	JJ
cord-277648-9kxwkcbl	282	3	phagocytes	phagocyte	NNS
cord-277648-9kxwkcbl	282	4	,	,	,
cord-277648-9kxwkcbl	282	5	iterative	iterative	JJ
cord-277648-9kxwkcbl	282	6	data	data	NN
cord-277648-9kxwkcbl	282	7	integration	integration	NN
cord-277648-9kxwkcbl	282	8	was	be	VBD
cord-277648-9kxwkcbl	282	9	performed	perform	VBN
cord-277648-9kxwkcbl	282	10	using	use	VBG
cord-277648-9kxwkcbl	282	11	the	the	DT
cord-277648-9kxwkcbl	282	12	integration	integration	NN
cord-277648-9kxwkcbl	282	13	procedure	procedure	NN
cord-277648-9kxwkcbl	282	14	described	describe	VBN
cord-277648-9kxwkcbl	282	15	above	above	RB
cord-277648-9kxwkcbl	282	16	,	,	,
cord-277648-9kxwkcbl	282	17	with	with	IN
cord-277648-9kxwkcbl	282	18	a	a	DT
cord-277648-9kxwkcbl	282	19	k.filter	k.filter	NNP
cord-277648-9kxwkcbl	282	20	parameter	parameter	NN
cord-277648-9kxwkcbl	282	21	of	of	IN
cord-277648-9kxwkcbl	282	22	112	112	CD
cord-277648-9kxwkcbl	282	23	for	for	IN
cord-277648-9kxwkcbl	282	24	'	'	``
cord-277648-9kxwkcbl	282	25	FindIntegrationAnchors	findintegrationanchor	NNS
cord-277648-9kxwkcbl	282	26	'	'	POS
cord-277648-9kxwkcbl	282	27	and	and	CC
cord-277648-9kxwkcbl	282	28	a	a	DT
cord-277648-9kxwkcbl	282	29	resolution	resolution	NN
cord-277648-9kxwkcbl	282	30	parameter	parameter	NN
cord-277648-9kxwkcbl	282	31	of	of	IN
cord-277648-9kxwkcbl	282	32	0.8	0.8	CD
cord-277648-9kxwkcbl	282	33	for	for	IN
cord-277648-9kxwkcbl	282	34	'	'	``
cord-277648-9kxwkcbl	282	35	FindClusters	FindClusters	NNP
cord-277648-9kxwkcbl	282	36	'	'	''
cord-277648-9kxwkcbl	282	37	.	.	.
cord-277648-9kxwkcbl	283	1	The	the	DT
cord-277648-9kxwkcbl	283	2	resulting	result	VBG
cord-277648-9kxwkcbl	283	3	fine	fine	JJ
cord-277648-9kxwkcbl	283	4	-	-	HYPH
cord-277648-9kxwkcbl	283	5	scale	scale	NN
cord-277648-9kxwkcbl	283	6	mononuclear	mononuclear	JJ
cord-277648-9kxwkcbl	283	7	phagocyte	phagocyte	NN
cord-277648-9kxwkcbl	283	8	clusters	cluster	NNS
cord-277648-9kxwkcbl	283	9	were	be	VBD
cord-277648-9kxwkcbl	283	10	left	leave	VBN
cord-277648-9kxwkcbl	283	11	unannotated	unannotated	JJ
cord-277648-9kxwkcbl	283	12	during	during	IN
cord-277648-9kxwkcbl	283	13	further	further	JJ
cord-277648-9kxwkcbl	283	14	analysis	analysis	NN
cord-277648-9kxwkcbl	283	15	,	,	,
cord-277648-9kxwkcbl	283	16	but	but	CC
cord-277648-9kxwkcbl	283	17	were	be	VBD
cord-277648-9kxwkcbl	283	18	tested	test	VBN
cord-277648-9kxwkcbl	283	19	using	use	VBG
cord-277648-9kxwkcbl	283	20	the	the	DT
cord-277648-9kxwkcbl	283	21	BALF	BALF	NNP
cord-277648-9kxwkcbl	283	22	marker	marker	NN
cord-277648-9kxwkcbl	283	23	gene	gene	NN
cord-277648-9kxwkcbl	283	24	panel	panel	NN
cord-277648-9kxwkcbl	283	25	to	to	TO
cord-277648-9kxwkcbl	283	26	identify	identify	VB
cord-277648-9kxwkcbl	283	27	probable	probable	JJ
cord-277648-9kxwkcbl	283	28	doublets	doublet	NNS
cord-277648-9kxwkcbl	283	29	.	.	.
cord-277648-9kxwkcbl	284	1	For	for	IN
cord-277648-9kxwkcbl	284	2	T	T	NNP
cord-277648-9kxwkcbl	284	3	and	and	CC
cord-277648-9kxwkcbl	284	4	NK	NK	NNP
cord-277648-9kxwkcbl	284	5	cells	cell	NNS
cord-277648-9kxwkcbl	284	6	,	,	,
cord-277648-9kxwkcbl	284	7	iterative	iterative	JJ
cord-277648-9kxwkcbl	284	8	data	datum	NNS
cord-277648-9kxwkcbl	284	9	integration	integration	NN
cord-277648-9kxwkcbl	284	10	was	be	VBD
cord-277648-9kxwkcbl	284	11	performed	perform	VBN
cord-277648-9kxwkcbl	284	12	using	use	VBG
cord-277648-9kxwkcbl	284	13	the	the	DT
cord-277648-9kxwkcbl	284	14	integration	integration	NN
cord-277648-9kxwkcbl	284	15	procedure	procedure	NN
cord-277648-9kxwkcbl	284	16	described	describe	VBN
cord-277648-9kxwkcbl	284	17	above	above	RB
cord-277648-9kxwkcbl	284	18	,	,	,
cord-277648-9kxwkcbl	284	19	with	with	IN
cord-277648-9kxwkcbl	284	20	a	a	DT
cord-277648-9kxwkcbl	284	21	k.filter	k.filter	JJ
cord-277648-9kxwkcbl	284	22	parameter	parameter	NN
cord-277648-9kxwkcbl	284	23	of	of	IN
cord-277648-9kxwkcbl	284	24	175	175	CD
cord-277648-9kxwkcbl	284	25	and	and	CC
cord-277648-9kxwkcbl	284	26	a	a	DT
cord-277648-9kxwkcbl	284	27	resolution	resolution	NN
cord-277648-9kxwkcbl	284	28	parameter	parameter	NN
cord-277648-9kxwkcbl	284	29	of	of	IN
cord-277648-9kxwkcbl	284	30	0.8	0.8	CD
cord-277648-9kxwkcbl	284	31	.	.	.
cord-277648-9kxwkcbl	285	1	In	in	IN
cord-277648-9kxwkcbl	285	2	order	order	NN
cord-277648-9kxwkcbl	285	3	to	to	TO
cord-277648-9kxwkcbl	285	4	filter	filter	VB
cord-277648-9kxwkcbl	285	5	anchors	anchor	NNS
cord-277648-9kxwkcbl	285	6	for	for	IN
cord-277648-9kxwkcbl	285	7	T	T	NNP
cord-277648-9kxwkcbl	285	8	/	/	SYM
cord-277648-9kxwkcbl	285	9	NK	NK	NNP
cord-277648-9kxwkcbl	285	10	re	re	NN
cord-277648-9kxwkcbl	285	11	-	-	NN
cord-277648-9kxwkcbl	285	12	integration	integration	NN
cord-277648-9kxwkcbl	285	13	,	,	,
cord-277648-9kxwkcbl	285	14	one	one	CD
cord-277648-9kxwkcbl	285	15	healthy	healthy	JJ
cord-277648-9kxwkcbl	285	16	control	control	NN
cord-277648-9kxwkcbl	285	17	donor	donor	NN
cord-277648-9kxwkcbl	285	18	(	(	-LRB-
cord-277648-9kxwkcbl	285	19	HC2	HC2	NNP
cord-277648-9kxwkcbl	285	20	,	,	,
cord-277648-9kxwkcbl	285	21	60	60	CD
cord-277648-9kxwkcbl	285	22	cells	cell	NNS
cord-277648-9kxwkcbl	285	23	)	)	-RRB-
cord-277648-9kxwkcbl	285	24	and	and	CC
cord-277648-9kxwkcbl	285	25	one	one	CD
cord-277648-9kxwkcbl	285	26	severe	severe	JJ
cord-277648-9kxwkcbl	285	27	donor	donor	NN
cord-277648-9kxwkcbl	285	28	(	(	-LRB-
cord-277648-9kxwkcbl	285	29	S3	S3	NNP
cord-277648-9kxwkcbl	285	30	,	,	,
cord-277648-9kxwkcbl	285	31	72	72	CD
cord-277648-9kxwkcbl	285	32	cells	cell	NNS
cord-277648-9kxwkcbl	285	33	)	)	-RRB-
cord-277648-9kxwkcbl	285	34	with	with	IN
cord-277648-9kxwkcbl	285	35	small	small	JJ
cord-277648-9kxwkcbl	285	36	numbers	number	NNS
cord-277648-9kxwkcbl	285	37	of	of	IN
cord-277648-9kxwkcbl	285	38	T	T	NNP
cord-277648-9kxwkcbl	285	39	/	/	SYM
cord-277648-9kxwkcbl	285	40	NK	NK	NNP
cord-277648-9kxwkcbl	285	41	cells	cell	NNS
cord-277648-9kxwkcbl	285	42	were	be	VBD
cord-277648-9kxwkcbl	285	43	excluded	exclude	VBN
cord-277648-9kxwkcbl	285	44	from	from	IN
cord-277648-9kxwkcbl	285	45	the	the	DT
cord-277648-9kxwkcbl	285	46	integration	integration	NN
cord-277648-9kxwkcbl	285	47	and	and	CC
cord-277648-9kxwkcbl	285	48	subsequent	subsequent	JJ
cord-277648-9kxwkcbl	285	49	analysis	analysis	NN
cord-277648-9kxwkcbl	285	50	.	.	.
cord-277648-9kxwkcbl	286	1	T	T	NNP
cord-277648-9kxwkcbl	286	2	and	and	CC
cord-277648-9kxwkcbl	286	3	NK	NK	NNP
cord-277648-9kxwkcbl	286	4	cell	cell	NN
cord-277648-9kxwkcbl	286	5	fine	fine	JJ
cord-277648-9kxwkcbl	286	6	-	-	HYPH
cord-277648-9kxwkcbl	286	7	level	level	NN
cord-277648-9kxwkcbl	286	8	clusters	cluster	NNS
cord-277648-9kxwkcbl	286	9	were	be	VBD
cord-277648-9kxwkcbl	286	10	annotated	annotate	VBN
cord-277648-9kxwkcbl	286	11	according	accord	VBG
cord-277648-9kxwkcbl	286	12	to	to	IN
cord-277648-9kxwkcbl	286	13	a	a	DT
cord-277648-9kxwkcbl	286	14	panel	panel	NN
cord-277648-9kxwkcbl	286	15	of	of	IN
cord-277648-9kxwkcbl	286	16	canonical	canonical	JJ
cord-277648-9kxwkcbl	286	17	T	T	NNP
cord-277648-9kxwkcbl	286	18	and	and	CC
cord-277648-9kxwkcbl	286	19	NK	NK	NNP
cord-277648-9kxwkcbl	286	20	cell	cell	NN
cord-277648-9kxwkcbl	286	21	marker	marker	NN
cord-277648-9kxwkcbl	286	22	genes	gene	NNS
cord-277648-9kxwkcbl	286	23	,	,	,
cord-277648-9kxwkcbl	286	24	available	available	JJ
cord-277648-9kxwkcbl	286	25	in	in	IN
cord-277648-9kxwkcbl	286	26	Supplemental	supplemental	JJ
cord-277648-9kxwkcbl	286	27	Figure	Figure	NNP
cord-277648-9kxwkcbl	286	28	S1	s1	NN
cord-277648-9kxwkcbl	286	29	.	.	.
cord-277648-9kxwkcbl	287	1	The	the	DT
cord-277648-9kxwkcbl	287	2	original	original	JJ
cord-277648-9kxwkcbl	287	3	integration	integration	NN
cord-277648-9kxwkcbl	287	4	of	of	IN
cord-277648-9kxwkcbl	287	5	PBMC	PBMC	NNP
cord-277648-9kxwkcbl	287	6	mutli	mutli	JJ
cord-277648-9kxwkcbl	287	7	-	-	HYPH
cord-277648-9kxwkcbl	287	8	donor	donor	NN
cord-277648-9kxwkcbl	287	9	datasets	dataset	NNS
cord-277648-9kxwkcbl	287	10	allowed	allow	VBD
cord-277648-9kxwkcbl	287	11	cell	cell	NN
cord-277648-9kxwkcbl	287	12	type	type	NN
cord-277648-9kxwkcbl	287	13	annotation	annotation	NN
cord-277648-9kxwkcbl	287	14	at	at	IN
cord-277648-9kxwkcbl	287	15	a	a	DT
cord-277648-9kxwkcbl	287	16	fine	fine	JJ
cord-277648-9kxwkcbl	287	17	level	level	NN
cord-277648-9kxwkcbl	287	18	and	and	CC
cord-277648-9kxwkcbl	287	19	did	do	VBD
cord-277648-9kxwkcbl	287	20	not	not	RB
cord-277648-9kxwkcbl	287	21	require	require	VB
cord-277648-9kxwkcbl	287	22	iterative	iterative	JJ
cord-277648-9kxwkcbl	287	23	data	datum	NNS
cord-277648-9kxwkcbl	287	24	integration	integration	NN
cord-277648-9kxwkcbl	287	25	.	.	.
cord-277648-9kxwkcbl	288	1	Compositional	compositional	JJ
cord-277648-9kxwkcbl	288	2	changes	change	NNS
cord-277648-9kxwkcbl	288	3	across	across	IN
cord-277648-9kxwkcbl	288	4	disease	disease	NN
cord-277648-9kxwkcbl	288	5	severity	severity	NN
cord-277648-9kxwkcbl	288	6	categories	category	NNS
cord-277648-9kxwkcbl	288	7	were	be	VBD
cord-277648-9kxwkcbl	288	8	assessed	assess	VBN
cord-277648-9kxwkcbl	288	9	for	for	IN
cord-277648-9kxwkcbl	288	10	BALF	BALF	NNP
cord-277648-9kxwkcbl	288	11	and	and	CC
cord-277648-9kxwkcbl	288	12	PBMC	PBMC	NNP
cord-277648-9kxwkcbl	288	13	datasets	dataset	NNS
cord-277648-9kxwkcbl	288	14	separately	separately	RB
cord-277648-9kxwkcbl	288	15	using	use	VBG
cord-277648-9kxwkcbl	288	16	:	:	:
cord-277648-9kxwkcbl	288	17	1	1	LS
cord-277648-9kxwkcbl	288	18	)	)	-RRB-
cord-277648-9kxwkcbl	288	19	donor	donor	NN
cord-277648-9kxwkcbl	288	20	-	-	HYPH
cord-277648-9kxwkcbl	288	21	specific	specific	JJ
cord-277648-9kxwkcbl	288	22	fractional	fractional	JJ
cord-277648-9kxwkcbl	288	23	contributions	contribution	NNS
cord-277648-9kxwkcbl	288	24	to	to	IN
cord-277648-9kxwkcbl	288	25	each	each	DT
cord-277648-9kxwkcbl	288	26	cell	cell	NN
cord-277648-9kxwkcbl	288	27	type	type	NN
cord-277648-9kxwkcbl	288	28	in	in	IN
cord-277648-9kxwkcbl	288	29	the	the	DT
cord-277648-9kxwkcbl	288	30	total	total	JJ
cord-277648-9kxwkcbl	288	31	pool	pool	NN
cord-277648-9kxwkcbl	288	32	of	of	IN
cord-277648-9kxwkcbl	288	33	cells	cell	NNS
cord-277648-9kxwkcbl	288	34	recovered	recover	VBN
cord-277648-9kxwkcbl	288	35	from	from	IN
cord-277648-9kxwkcbl	288	36	all	all	DT
cord-277648-9kxwkcbl	288	37	donors	donor	NNS
cord-277648-9kxwkcbl	288	38	,	,	,
cord-277648-9kxwkcbl	288	39	2	2	CD
cord-277648-9kxwkcbl	288	40	)	)	-RRB-
cord-277648-9kxwkcbl	288	41	donor	donor	NN
cord-277648-9kxwkcbl	288	42	-	-	HYPH
cord-277648-9kxwkcbl	288	43	specific	specific	JJ
cord-277648-9kxwkcbl	288	44	percentages	percentage	NNS
cord-277648-9kxwkcbl	288	45	of	of	IN
cord-277648-9kxwkcbl	288	46	cell	cell	NN
cord-277648-9kxwkcbl	288	47	types	type	NNS
cord-277648-9kxwkcbl	288	48	comprising	comprise	VBG
cord-277648-9kxwkcbl	288	49	each	each	DT
cord-277648-9kxwkcbl	288	50	pool	pool	NN
cord-277648-9kxwkcbl	288	51	of	of	IN
cord-277648-9kxwkcbl	288	52	cells	cell	NNS
cord-277648-9kxwkcbl	288	53	recovered	recover	VBN
cord-277648-9kxwkcbl	288	54	from	from	IN
cord-277648-9kxwkcbl	288	55	individual	individual	JJ
cord-277648-9kxwkcbl	288	56	donor	donor	NN
cord-277648-9kxwkcbl	288	57	severity	severity	NN
cord-277648-9kxwkcbl	288	58	conditions	condition	NNS
cord-277648-9kxwkcbl	288	59	(	(	-LRB-
cord-277648-9kxwkcbl	288	60	severe	severe	JJ
cord-277648-9kxwkcbl	288	61	,	,	,
cord-277648-9kxwkcbl	288	62	moderate	moderate	JJ
cord-277648-9kxwkcbl	288	63	,	,	,
cord-277648-9kxwkcbl	288	64	or	or	CC
cord-277648-9kxwkcbl	288	65	healthy	healthy	JJ
cord-277648-9kxwkcbl	288	66	control	control	NN
cord-277648-9kxwkcbl	288	67	for	for	IN
cord-277648-9kxwkcbl	288	68	BALF	BALF	NNP
cord-277648-9kxwkcbl	288	69	,	,	,
cord-277648-9kxwkcbl	288	70	ARDS	ARDS	NNP
cord-277648-9kxwkcbl	288	71	,	,	,
cord-277648-9kxwkcbl	288	72	non	non	NNP
cord-277648-9kxwkcbl	288	73	-	-	NNP
cord-277648-9kxwkcbl	288	74	ARDS	ARDS	NNP
cord-277648-9kxwkcbl	288	75	,	,	,
cord-277648-9kxwkcbl	288	76	or	or	CC
cord-277648-9kxwkcbl	288	77	healthy	healthy	JJ
cord-277648-9kxwkcbl	288	78	control	control	NN
cord-277648-9kxwkcbl	288	79	for	for	IN
cord-277648-9kxwkcbl	288	80	PBMCs	PBMCs	NNP
cord-277648-9kxwkcbl	288	81	)	)	-RRB-
cord-277648-9kxwkcbl	288	82	,	,	,
cord-277648-9kxwkcbl	288	83	and	and	CC
cord-277648-9kxwkcbl	288	84	3	3	LS
cord-277648-9kxwkcbl	288	85	)	)	-RRB-
cord-277648-9kxwkcbl	288	86	percentages	percentage	NNS
cord-277648-9kxwkcbl	288	87	of	of	IN
cord-277648-9kxwkcbl	288	88	cell	cell	NN
cord-277648-9kxwkcbl	288	89	types	type	NNS
cord-277648-9kxwkcbl	288	90	in	in	IN
cord-277648-9kxwkcbl	288	91	each	each	DT
cord-277648-9kxwkcbl	288	92	donor	donor	NN
cord-277648-9kxwkcbl	288	93	sample	sample	NN
cord-277648-9kxwkcbl	288	94	z	z	NN
cord-277648-9kxwkcbl	288	95	-	-	:
cord-277648-9kxwkcbl	288	96	scored	score	VBN
cord-277648-9kxwkcbl	288	97	across	across	IN
cord-277648-9kxwkcbl	288	98	donors	donor	NNS
cord-277648-9kxwkcbl	288	99	.	.	.
cord-277648-9kxwkcbl	289	1	Here	here	RB
cord-277648-9kxwkcbl	289	2	,	,	,
cord-277648-9kxwkcbl	289	3	we	-PRON-	PRP
cord-277648-9kxwkcbl	289	4	did	do	VBD
cord-277648-9kxwkcbl	289	5	not	not	RB
cord-277648-9kxwkcbl	289	6	employ	employ	VB
cord-277648-9kxwkcbl	289	7	low	low	RB
cord-277648-9kxwkcbl	289	8	-	-	HYPH
cord-277648-9kxwkcbl	289	9	powered	powered	JJ
cord-277648-9kxwkcbl	289	10	statistical	statistical	JJ
cord-277648-9kxwkcbl	289	11	tests	test	NNS
cord-277648-9kxwkcbl	289	12	but	but	CC
cord-277648-9kxwkcbl	289	13	instead	instead	RB
cord-277648-9kxwkcbl	289	14	sought	seek	VBD
cord-277648-9kxwkcbl	289	15	to	to	TO
cord-277648-9kxwkcbl	289	16	use	use	VB
cord-277648-9kxwkcbl	289	17	method	method	NN
cord-277648-9kxwkcbl	289	18	3	3	CD
cord-277648-9kxwkcbl	289	19	to	to	TO
cord-277648-9kxwkcbl	289	20	highlight	highlight	VB
cord-277648-9kxwkcbl	289	21	donor	donor	NN
cord-277648-9kxwkcbl	289	22	-	-	HYPH
cord-277648-9kxwkcbl	289	23	to	to	IN
cord-277648-9kxwkcbl	289	24	-	-	HYPH
cord-277648-9kxwkcbl	289	25	donor	donor	NN
cord-277648-9kxwkcbl	289	26	variation	variation	NN
cord-277648-9kxwkcbl	289	27	in	in	IN
cord-277648-9kxwkcbl	289	28	cell	cell	NN
cord-277648-9kxwkcbl	289	29	type	type	NN
cord-277648-9kxwkcbl	289	30	composition	composition	NN
cord-277648-9kxwkcbl	289	31	and	and	CC
cord-277648-9kxwkcbl	289	32	identify	identify	VB
cord-277648-9kxwkcbl	289	33	robust	robust	JJ
cord-277648-9kxwkcbl	289	34	trends	trend	NNS
cord-277648-9kxwkcbl	289	35	across	across	IN
cord-277648-9kxwkcbl	289	36	donors	donor	NNS
cord-277648-9kxwkcbl	289	37	indicating	indicate	VBG
cord-277648-9kxwkcbl	289	38	possible	possible	JJ
cord-277648-9kxwkcbl	289	39	expansion	expansion	NN
cord-277648-9kxwkcbl	289	40	or	or	CC
cord-277648-9kxwkcbl	289	41	cytopenia	cytopenia	NNP
cord-277648-9kxwkcbl	289	42	.	.	.
cord-277648-9kxwkcbl	290	1	Differential	differential	JJ
cord-277648-9kxwkcbl	290	2	expression	expression	NN
cord-277648-9kxwkcbl	290	3	analysis	analysis	NN
cord-277648-9kxwkcbl	290	4	was	be	VBD
cord-277648-9kxwkcbl	290	5	performed	perform	VBN
cord-277648-9kxwkcbl	290	6	in	in	IN
cord-277648-9kxwkcbl	290	7	Seurat	Seurat	NNP
cord-277648-9kxwkcbl	290	8	using	use	VBG
cord-277648-9kxwkcbl	290	9	the	the	DT
cord-277648-9kxwkcbl	290	10	'	'	``
cord-277648-9kxwkcbl	290	11	FindMarkers	FindMarkers	NNP
cord-277648-9kxwkcbl	290	12	'	'	POS
cord-277648-9kxwkcbl	290	13	function	function	NN
cord-277648-9kxwkcbl	290	14	utilizing	utilize	VBG
cord-277648-9kxwkcbl	290	15	model	model	NN
cord-277648-9kxwkcbl	290	16	-	-	HYPH
cord-277648-9kxwkcbl	290	17	based	base	VBN
cord-277648-9kxwkcbl	290	18	analysis	analysis	NN
cord-277648-9kxwkcbl	290	19	of	of	IN
cord-277648-9kxwkcbl	290	20	single	single	JJ
cord-277648-9kxwkcbl	290	21	-	-	HYPH
cord-277648-9kxwkcbl	290	22	cell	cell	NN
cord-277648-9kxwkcbl	290	23	transcriptomics	transcriptomic	NNS
cord-277648-9kxwkcbl	290	24	(	(	-LRB-
cord-277648-9kxwkcbl	290	25	MAST	MAST	NNP
cord-277648-9kxwkcbl	290	26	)	)	-RRB-
cord-277648-9kxwkcbl	290	27	statistical	statistical	JJ
cord-277648-9kxwkcbl	290	28	framework	framework	NN
cord-277648-9kxwkcbl	290	29	through	through	IN
cord-277648-9kxwkcbl	290	30	the	the	DT
cord-277648-9kxwkcbl	290	31	"	"	``
cord-277648-9kxwkcbl	290	32	MAST	mast	NN
cord-277648-9kxwkcbl	290	33	"	"	''
cord-277648-9kxwkcbl	290	34	R	r	NN
cord-277648-9kxwkcbl	290	35	package	package	NN
cord-277648-9kxwkcbl	290	36	(	(	-LRB-
cord-277648-9kxwkcbl	290	37	v.	v.	NN
cord-277648-9kxwkcbl	290	38	3.11	3.11	CD
cord-277648-9kxwkcbl	290	39	)	)	-RRB-
cord-277648-9kxwkcbl	290	40	[	[	-LRB-
cord-277648-9kxwkcbl	290	41	66	66	CD
cord-277648-9kxwkcbl	290	42	]	]	-RRB-
cord-277648-9kxwkcbl	290	43	.	.	.
cord-277648-9kxwkcbl	291	1	Differential	differential	JJ
cord-277648-9kxwkcbl	291	2	expression	expression	NN
cord-277648-9kxwkcbl	291	3	analysis	analysis	NN
cord-277648-9kxwkcbl	291	4	was	be	VBD
cord-277648-9kxwkcbl	291	5	conducted	conduct	VBN
cord-277648-9kxwkcbl	291	6	for	for	IN
cord-277648-9kxwkcbl	291	7	all	all	DT
cord-277648-9kxwkcbl	291	8	cell	cell	NN
cord-277648-9kxwkcbl	291	9	types	type	NNS
cord-277648-9kxwkcbl	291	10	in	in	IN
cord-277648-9kxwkcbl	291	11	the	the	DT
cord-277648-9kxwkcbl	291	12	integrated	integrate	VBN
cord-277648-9kxwkcbl	291	13	BALF	BALF	NNP
cord-277648-9kxwkcbl	291	14	dataset	dataset	NN
cord-277648-9kxwkcbl	291	15	across	across	IN
cord-277648-9kxwkcbl	291	16	three	three	CD
cord-277648-9kxwkcbl	291	17	permutations	permutation	NNS
cord-277648-9kxwkcbl	291	18	of	of	IN
cord-277648-9kxwkcbl	291	19	donor	donor	NN
cord-277648-9kxwkcbl	291	20	groups	group	NNS
cord-277648-9kxwkcbl	291	21	:	:	:
cord-277648-9kxwkcbl	291	22	severe	severe	JJ
cord-277648-9kxwkcbl	291	23	vs.	vs.	FW
cord-277648-9kxwkcbl	291	24	moderate	moderate	JJ
cord-277648-9kxwkcbl	291	25	,	,	,
cord-277648-9kxwkcbl	291	26	moderate	moderate	JJ
cord-277648-9kxwkcbl	291	27	vs.	vs.	CC
cord-277648-9kxwkcbl	291	28	control	control	NN
cord-277648-9kxwkcbl	291	29	,	,	,
cord-277648-9kxwkcbl	291	30	and	and	CC
cord-277648-9kxwkcbl	291	31	severe	severe	JJ
cord-277648-9kxwkcbl	291	32	vs.	vs.	NN
cord-277648-9kxwkcbl	291	33	control	control	NN
cord-277648-9kxwkcbl	291	34	.	.	.
cord-277648-9kxwkcbl	292	1	For	for	IN
cord-277648-9kxwkcbl	292	2	all	all	DT
cord-277648-9kxwkcbl	292	3	cell	cell	NN
cord-277648-9kxwkcbl	292	4	types	type	NNS
cord-277648-9kxwkcbl	292	5	in	in	IN
cord-277648-9kxwkcbl	292	6	the	the	DT
cord-277648-9kxwkcbl	292	7	PBMC	PBMC	NNP
cord-277648-9kxwkcbl	292	8	dataset	dataset	NN
cord-277648-9kxwkcbl	292	9	,	,	,
cord-277648-9kxwkcbl	292	10	differential	differential	JJ
cord-277648-9kxwkcbl	292	11	expression	expression	NN
cord-277648-9kxwkcbl	292	12	analysis	analysis	NN
cord-277648-9kxwkcbl	292	13	was	be	VBD
cord-277648-9kxwkcbl	292	14	conducted	conduct	VBN
cord-277648-9kxwkcbl	292	15	across	across	IN
cord-277648-9kxwkcbl	292	16	three	three	CD
cord-277648-9kxwkcbl	292	17	permutations	permutation	NNS
cord-277648-9kxwkcbl	292	18	of	of	IN
cord-277648-9kxwkcbl	292	19	donor	donor	NN
cord-277648-9kxwkcbl	292	20	groups	group	NNS
cord-277648-9kxwkcbl	292	21	:	:	:
cord-277648-9kxwkcbl	292	22	ARDS	ARDS	NNP
cord-277648-9kxwkcbl	292	23	vs.	vs.	IN
cord-277648-9kxwkcbl	292	24	non	non	NNP
cord-277648-9kxwkcbl	292	25	-	-	NNP
cord-277648-9kxwkcbl	292	26	ARDS	ARDS	NNP
cord-277648-9kxwkcbl	292	27	,	,	,
cord-277648-9kxwkcbl	292	28	non	non	NNP
cord-277648-9kxwkcbl	292	29	-	-	JJ
cord-277648-9kxwkcbl	292	30	ARDS	ARDS	NNP
cord-277648-9kxwkcbl	292	31	vs.	vs.	IN
cord-277648-9kxwkcbl	292	32	control	control	NN
cord-277648-9kxwkcbl	292	33	,	,	,
cord-277648-9kxwkcbl	292	34	and	and	CC
cord-277648-9kxwkcbl	292	35	ARDS	ARDS	NNP
cord-277648-9kxwkcbl	292	36	vs.	vs.	CC
cord-277648-9kxwkcbl	292	37	control	control	NN
cord-277648-9kxwkcbl	292	38	Significantly	significantly	RB
cord-277648-9kxwkcbl	292	39	differentially	differentially	RB
cord-277648-9kxwkcbl	292	40	expressed	express	VBN
cord-277648-9kxwkcbl	292	41	genes	gene	NNS
cord-277648-9kxwkcbl	292	42	(	(	-LRB-
cord-277648-9kxwkcbl	292	43	DEGs	deg	NNS
cord-277648-9kxwkcbl	292	44	)	)	-RRB-
cord-277648-9kxwkcbl	292	45	are	be	VBP
cord-277648-9kxwkcbl	292	46	indicated	indicate	VBN
cord-277648-9kxwkcbl	292	47	by	by	IN
cord-277648-9kxwkcbl	292	48	having	have	VBG
cord-277648-9kxwkcbl	292	49	a	a	DT
cord-277648-9kxwkcbl	292	50	MAST	mast	NN
cord-277648-9kxwkcbl	292	51	adjusted	adjust	VBN
cord-277648-9kxwkcbl	292	52	p<0.05	p<0.05	NN
cord-277648-9kxwkcbl	292	53	and	and	CC
cord-277648-9kxwkcbl	292	54	a	a	DT
cord-277648-9kxwkcbl	292	55	natural	natural	JJ
cord-277648-9kxwkcbl	292	56	log	log	NN
cord-277648-9kxwkcbl	292	57	fold	fold	NN
cord-277648-9kxwkcbl	292	58	change	change	NN
cord-277648-9kxwkcbl	292	59	threshold	threshold	NN
cord-277648-9kxwkcbl	292	60	of	of	IN
cord-277648-9kxwkcbl	292	61	0.25	0.25	CD
cord-277648-9kxwkcbl	292	62	was	be	VBD
cord-277648-9kxwkcbl	292	63	applied	apply	VBN
cord-277648-9kxwkcbl	292	64	.	.	.
cord-277648-9kxwkcbl	293	1	The	the	DT
cord-277648-9kxwkcbl	293	2	identification	identification	NN
cord-277648-9kxwkcbl	293	3	of	of	IN
cord-277648-9kxwkcbl	293	4	cell	cell	NN
cord-277648-9kxwkcbl	293	5	surface	surface	NN
cord-277648-9kxwkcbl	293	6	markers	marker	NNS
cord-277648-9kxwkcbl	293	7	indicative	indicative	JJ
cord-277648-9kxwkcbl	293	8	of	of	IN
cord-277648-9kxwkcbl	293	9	severe	severe	JJ
cord-277648-9kxwkcbl	293	10	disease	disease	NN
cord-277648-9kxwkcbl	293	11	was	be	VBD
cord-277648-9kxwkcbl	293	12	performed	perform	VBN
cord-277648-9kxwkcbl	293	13	by	by	IN
cord-277648-9kxwkcbl	293	14	crossreferencing	crossreference	VBG
cord-277648-9kxwkcbl	293	15	all	all	DT
cord-277648-9kxwkcbl	293	16	DEGs	deg	NNS
cord-277648-9kxwkcbl	293	17	across	across	IN
cord-277648-9kxwkcbl	293	18	disease	disease	NN
cord-277648-9kxwkcbl	293	19	severity	severity	NN
cord-277648-9kxwkcbl	293	20	levels	level	NNS
cord-277648-9kxwkcbl	293	21	in	in	IN
cord-277648-9kxwkcbl	293	22	the	the	DT
cord-277648-9kxwkcbl	293	23	integrated	integrate	VBN
cord-277648-9kxwkcbl	293	24	BALF	BALF	NNP
cord-277648-9kxwkcbl	293	25	and	and	CC
cord-277648-9kxwkcbl	293	26	PBMC	PBMC	NNP
cord-277648-9kxwkcbl	293	27	datasets	dataset	NNS
cord-277648-9kxwkcbl	293	28	with	with	IN
cord-277648-9kxwkcbl	293	29	entries	entry	NNS
cord-277648-9kxwkcbl	293	30	in	in	IN
cord-277648-9kxwkcbl	293	31	the	the	DT
cord-277648-9kxwkcbl	293	32	Cell	Cell	NNP
cord-277648-9kxwkcbl	293	33	Surface	Surface	NNP
cord-277648-9kxwkcbl	293	34	Protein	Protein	NNP
cord-277648-9kxwkcbl	293	35	Atlas	Atlas	NNP
cord-277648-9kxwkcbl	293	36	(	(	-LRB-
cord-277648-9kxwkcbl	293	37	CSPA	CSPA	NNP
cord-277648-9kxwkcbl	293	38	)	)	-RRB-
cord-277648-9kxwkcbl	293	39	[	[	-LRB-
cord-277648-9kxwkcbl	293	40	38	38	CD
cord-277648-9kxwkcbl	293	41	]	]	-RRB-
cord-277648-9kxwkcbl	293	42	.	.	.
cord-277648-9kxwkcbl	294	1	DEGs	DEGs	NNP
cord-277648-9kxwkcbl	294	2	were	be	VBD
cord-277648-9kxwkcbl	294	3	considered	consider	VBN
cord-277648-9kxwkcbl	294	4	to	to	TO
cord-277648-9kxwkcbl	294	5	be	be	VB
cord-277648-9kxwkcbl	294	6	differentially	differentially	RB
cord-277648-9kxwkcbl	294	7	expressed	express	VBN
cord-277648-9kxwkcbl	294	8	surface	surface	NN
cord-277648-9kxwkcbl	294	9	markers	marker	NNS
cord-277648-9kxwkcbl	294	10	if	if	IN
cord-277648-9kxwkcbl	294	11	they	-PRON-	PRP
cord-277648-9kxwkcbl	294	12	were	be	VBD
cord-277648-9kxwkcbl	294	13	included	include	VBN
cord-277648-9kxwkcbl	294	14	in	in	IN
cord-277648-9kxwkcbl	294	15	the	the	DT
cord-277648-9kxwkcbl	294	16	"	"	``
cord-277648-9kxwkcbl	294	17	high	high	JJ
cord-277648-9kxwkcbl	294	18	confidence	confidence	NN
cord-277648-9kxwkcbl	294	19	"	"	''
cord-277648-9kxwkcbl	294	20	CSPA	CSPA	NNP
cord-277648-9kxwkcbl	294	21	category	category	NN
cord-277648-9kxwkcbl	294	22	and	and	CC
cord-277648-9kxwkcbl	294	23	showed	show	VBD
cord-277648-9kxwkcbl	294	24	significant	significant	JJ
cord-277648-9kxwkcbl	294	25	differential	differential	JJ
cord-277648-9kxwkcbl	294	26	expression	expression	NN
cord-277648-9kxwkcbl	294	27	(	(	-LRB-
cord-277648-9kxwkcbl	294	28	adjusted	adjust	VBN
cord-277648-9kxwkcbl	294	29	p<0.05	p<0.05	CD
cord-277648-9kxwkcbl	294	30	)	)	-RRB-
cord-277648-9kxwkcbl	294	31	with	with	IN
cord-277648-9kxwkcbl	294	32	an	an	DT
cord-277648-9kxwkcbl	294	33	absolute	absolute	JJ
cord-277648-9kxwkcbl	294	34	value	value	NN
cord-277648-9kxwkcbl	294	35	average	average	JJ
cord-277648-9kxwkcbl	294	36	natural	natural	JJ
cord-277648-9kxwkcbl	294	37	log	log	NN
cord-277648-9kxwkcbl	294	38	fold	fold	NN
cord-277648-9kxwkcbl	294	39	change	change	NN
cord-277648-9kxwkcbl	294	40	greater	great	JJR
cord-277648-9kxwkcbl	294	41	than	than	IN
cord-277648-9kxwkcbl	294	42	0.693	0.693	CD
cord-277648-9kxwkcbl	294	43	(	(	-LRB-
cord-277648-9kxwkcbl	294	44	or	or	CC
cord-277648-9kxwkcbl	294	45	log	log	VB
cord-277648-9kxwkcbl	294	46	2	2	CD
cord-277648-9kxwkcbl	294	47	fold	fold	NN
cord-277648-9kxwkcbl	294	48	change	change	NN
cord-277648-9kxwkcbl	294	49	>	>	XX
cord-277648-9kxwkcbl	294	50	1	1	CD
cord-277648-9kxwkcbl	294	51	)	)	-RRB-
cord-277648-9kxwkcbl	294	52	.	.	.
cord-277648-9kxwkcbl	295	1	Differentially	differentially	RB
cord-277648-9kxwkcbl	295	2	expressed	express	VBN
cord-277648-9kxwkcbl	295	3	surface	surface	NN
cord-277648-9kxwkcbl	295	4	markers	marker	NNS
cord-277648-9kxwkcbl	295	5	were	be	VBD
cord-277648-9kxwkcbl	295	6	further	further	RB
cord-277648-9kxwkcbl	295	7	analyzed	analyze	VBN
cord-277648-9kxwkcbl	295	8	to	to	TO
cord-277648-9kxwkcbl	295	9	verify	verify	VB
cord-277648-9kxwkcbl	295	10	low	low	JJ
cord-277648-9kxwkcbl	295	11	expression	expression	NN
cord-277648-9kxwkcbl	295	12	in	in	IN
cord-277648-9kxwkcbl	295	13	moderate	moderate	JJ
cord-277648-9kxwkcbl	295	14	or	or	CC
cord-277648-9kxwkcbl	295	15	non	non	JJ
cord-277648-9kxwkcbl	295	16	-	-	JJ
cord-277648-9kxwkcbl	295	17	ARDS	ARDS	NNP
cord-277648-9kxwkcbl	295	18	and	and	CC
cord-277648-9kxwkcbl	295	19	control	control	NN
cord-277648-9kxwkcbl	295	20	donor	donor	NN
cord-277648-9kxwkcbl	295	21	samples	sample	NNS
cord-277648-9kxwkcbl	295	22	.	.	.
cord-277648-9kxwkcbl	296	1	Finally	finally	RB
cord-277648-9kxwkcbl	296	2	,	,	,
cord-277648-9kxwkcbl	296	3	differentially	differentially	RB
cord-277648-9kxwkcbl	296	4	expressed	express	VBN
cord-277648-9kxwkcbl	296	5	surface	surface	NN
cord-277648-9kxwkcbl	296	6	markers	marker	NNS
cord-277648-9kxwkcbl	296	7	were	be	VBD
cord-277648-9kxwkcbl	296	8	verified	verify	VBN
cord-277648-9kxwkcbl	296	9	to	to	TO
cord-277648-9kxwkcbl	296	10	be	be	VB
cord-277648-9kxwkcbl	296	11	expressed	express	VBN
cord-277648-9kxwkcbl	296	12	in	in	IN
cord-277648-9kxwkcbl	296	13	the	the	DT
cord-277648-9kxwkcbl	296	14	cell	cell	NN
cord-277648-9kxwkcbl	296	15	type	type	NN
cord-277648-9kxwkcbl	296	16	indicated	indicate	VBN
cord-277648-9kxwkcbl	296	17	by	by	IN
cord-277648-9kxwkcbl	296	18	our	-PRON-	PRP$
cord-277648-9kxwkcbl	296	19	data	datum	NNS
cord-277648-9kxwkcbl	296	20	by	by	IN
cord-277648-9kxwkcbl	296	21	cross	cross	NN
cord-277648-9kxwkcbl	296	22	referencing	reference	VBG
cord-277648-9kxwkcbl	296	23	with	with	IN
cord-277648-9kxwkcbl	296	24	the	the	DT
cord-277648-9kxwkcbl	296	25	Immune	Immune	NNP
cord-277648-9kxwkcbl	296	26	Cell	Cell	NNP
cord-277648-9kxwkcbl	296	27	Atlas	Atlas	NNP
cord-277648-9kxwkcbl	296	28	human	human	JJ
cord-277648-9kxwkcbl	296	29	bulk	bulk	NN
cord-277648-9kxwkcbl	296	30	RNA	RNA	NNP
cord-277648-9kxwkcbl	296	31	-	-	HYPH
cord-277648-9kxwkcbl	296	32	seq	seq	NNP
cord-277648-9kxwkcbl	296	33	data	datum	NNS
cord-277648-9kxwkcbl	296	34	[	[	-LRB-
cord-277648-9kxwkcbl	296	35	39	39	CD
cord-277648-9kxwkcbl	296	36	,	,	,
cord-277648-9kxwkcbl	296	37	40	40	CD
cord-277648-9kxwkcbl	296	38	]	]	-RRB-
cord-277648-9kxwkcbl	296	39	.	.	.
cord-277648-9kxwkcbl	297	1	Gene	gene	NN
cord-277648-9kxwkcbl	297	2	set	set	VBD
cord-277648-9kxwkcbl	297	3	enrichment	enrichment	NN
cord-277648-9kxwkcbl	297	4	analysis	analysis	NN
cord-277648-9kxwkcbl	297	5	(	(	-LRB-
cord-277648-9kxwkcbl	297	6	GSEA	GSEA	NNP
cord-277648-9kxwkcbl	297	7	)	)	-RRB-
cord-277648-9kxwkcbl	298	1	[	[	-LRB-
cord-277648-9kxwkcbl	298	2	67	67	CD
cord-277648-9kxwkcbl	298	3	]	]	-RRB-
cord-277648-9kxwkcbl	298	4	was	be	VBD
cord-277648-9kxwkcbl	298	5	performed	perform	VBN
cord-277648-9kxwkcbl	298	6	using	use	VBG
cord-277648-9kxwkcbl	298	7	the	the	DT
cord-277648-9kxwkcbl	298	8	"	"	``
cord-277648-9kxwkcbl	298	9	fgsea	fgsea	NN
cord-277648-9kxwkcbl	298	10	"	"	''
cord-277648-9kxwkcbl	298	11	package	package	NN
cord-277648-9kxwkcbl	298	12	(	(	-LRB-
cord-277648-9kxwkcbl	298	13	v.	v.	NN
cord-277648-9kxwkcbl	298	14	1.12.0	1.12.0	CD
cord-277648-9kxwkcbl	298	15	)	)	-RRB-
cord-277648-9kxwkcbl	299	1	[	[	-LRB-
cord-277648-9kxwkcbl	299	2	68	68	CD
cord-277648-9kxwkcbl	299	3	]	]	-RRB-
cord-277648-9kxwkcbl	300	1	in	in	IN
cord-277648-9kxwkcbl	300	2	R.	R.	NNP
cord-277648-9kxwkcbl	300	3	Differentially	differentially	RB
cord-277648-9kxwkcbl	300	4	expressed	express	VBD
cord-277648-9kxwkcbl	300	5	gene	gene	NN
cord-277648-9kxwkcbl	300	6	lists	list	NNS
cord-277648-9kxwkcbl	300	7	generated	generate	VBN
cord-277648-9kxwkcbl	300	8	using	use	VBG
cord-277648-9kxwkcbl	300	9	MAST	MAST	NNP
cord-277648-9kxwkcbl	300	10	were	be	VBD
cord-277648-9kxwkcbl	300	11	ranked	rank	VBN
cord-277648-9kxwkcbl	300	12	by	by	IN
cord-277648-9kxwkcbl	300	13	-log10(p	-log10(p	ADD
cord-277648-9kxwkcbl	300	14	)	)	-RRB-
cord-277648-9kxwkcbl	300	15	multiplied	multiply	VBN
cord-277648-9kxwkcbl	300	16	by	by	IN
cord-277648-9kxwkcbl	300	17	the	the	DT
cord-277648-9kxwkcbl	300	18	sign	sign	NN
cord-277648-9kxwkcbl	300	19	of	of	IN
cord-277648-9kxwkcbl	300	20	the	the	DT
cord-277648-9kxwkcbl	300	21	average	average	JJ
cord-277648-9kxwkcbl	300	22	natural	natural	JJ
cord-277648-9kxwkcbl	300	23	log	log	NN
cord-277648-9kxwkcbl	300	24	change	change	NN
cord-277648-9kxwkcbl	300	25	,	,	,
cord-277648-9kxwkcbl	300	26	as	as	IN
cord-277648-9kxwkcbl	300	27	previously	previously	RB
cord-277648-9kxwkcbl	300	28	demonstrated	demonstrate	VBN
cord-277648-9kxwkcbl	300	29	in	in	IN
cord-277648-9kxwkcbl	300	30	Debski	Debski	NNP
cord-277648-9kxwkcbl	300	31	et	et	NNP
cord-277648-9kxwkcbl	300	32	al	al	NNP
cord-277648-9kxwkcbl	300	33	.	.	.
cord-277648-9kxwkcbl	301	1	and	and	CC
cord-277648-9kxwkcbl	301	2	Riemand	Riemand	NNP
cord-277648-9kxwkcbl	301	3	et	et	NNP
cord-277648-9kxwkcbl	301	4	al	al	NNP
cord-277648-9kxwkcbl	301	5	.	.	.
cord-277648-9kxwkcbl	302	1	[	[	-LRB-
cord-277648-9kxwkcbl	302	2	69	69	CD
cord-277648-9kxwkcbl	302	3	,	,	,
cord-277648-9kxwkcbl	302	4	70	70	CD
cord-277648-9kxwkcbl	302	5	]	]	-RRB-
cord-277648-9kxwkcbl	302	6	,	,	,
cord-277648-9kxwkcbl	302	7	using	use	VBG
cord-277648-9kxwkcbl	302	8	the	the	DT
cord-277648-9kxwkcbl	302	9	MAST	mast	NN
cord-277648-9kxwkcbl	302	10	adjusted	adjust	VBN
cord-277648-9kxwkcbl	302	11	p	p	NN
cord-277648-9kxwkcbl	302	12	-	-	HYPH
cord-277648-9kxwkcbl	302	13	value	value	NN
cord-277648-9kxwkcbl	302	14	.	.	.
cord-277648-9kxwkcbl	303	1	Average	average	JJ
cord-277648-9kxwkcbl	303	2	natural	natural	JJ
cord-277648-9kxwkcbl	303	3	log	log	NN
cord-277648-9kxwkcbl	303	4	fold	fold	NN
cord-277648-9kxwkcbl	303	5	change	change	NN
cord-277648-9kxwkcbl	303	6	was	be	VBD
cord-277648-9kxwkcbl	303	7	used	use	VBN
cord-277648-9kxwkcbl	303	8	to	to	TO
cord-277648-9kxwkcbl	303	9	break	break	VB
cord-277648-9kxwkcbl	303	10	ranking	rank	VBG
cord-277648-9kxwkcbl	303	11	ties	tie	NNS
cord-277648-9kxwkcbl	303	12	and	and	CC
cord-277648-9kxwkcbl	303	13	this	this	DT
cord-277648-9kxwkcbl	303	14	value	value	NN
cord-277648-9kxwkcbl	303	15	also	also	RB
cord-277648-9kxwkcbl	303	16	served	serve	VBD
cord-277648-9kxwkcbl	303	17	as	as	IN
cord-277648-9kxwkcbl	303	18	an	an	DT
cord-277648-9kxwkcbl	303	19	input	input	NN
cord-277648-9kxwkcbl	303	20	to	to	IN
cord-277648-9kxwkcbl	303	21	GSEA	GSEA	NNP
cord-277648-9kxwkcbl	303	22	to	to	TO
cord-277648-9kxwkcbl	303	23	quantify	quantify	VB
cord-277648-9kxwkcbl	303	24	the	the	DT
cord-277648-9kxwkcbl	303	25	correlation	correlation	NN
cord-277648-9kxwkcbl	303	26	between	between	IN
cord-277648-9kxwkcbl	303	27	the	the	DT
cord-277648-9kxwkcbl	303	28	gene	gene	NN
cord-277648-9kxwkcbl	303	29	and	and	CC
cord-277648-9kxwkcbl	303	30	phenotype	phenotype	NN
cord-277648-9kxwkcbl	303	31	,	,	,
cord-277648-9kxwkcbl	303	32	as	as	IN
cord-277648-9kxwkcbl	303	33	-log10(p	-log10(p	NNP
cord-277648-9kxwkcbl	303	34	)	)	-RRB-
cord-277648-9kxwkcbl	303	35	values	value	NNS
cord-277648-9kxwkcbl	303	36	become	become	VBP
cord-277648-9kxwkcbl	303	37	arbitrarily	arbitrarily	RB
cord-277648-9kxwkcbl	303	38	large	large	JJ
cord-277648-9kxwkcbl	303	39	.	.	.
cord-277648-9kxwkcbl	304	1	GSEA	gsea	NN
cord-277648-9kxwkcbl	304	2	results	result	NNS
cord-277648-9kxwkcbl	304	3	were	be	VBD
cord-277648-9kxwkcbl	304	4	interpreted	interpret	VBN
cord-277648-9kxwkcbl	304	5	according	accord	VBG
cord-277648-9kxwkcbl	304	6	to	to	IN
cord-277648-9kxwkcbl	304	7	normalized	normalized	JJ
cord-277648-9kxwkcbl	304	8	enrichment	enrichment	NN
cord-277648-9kxwkcbl	304	9	score	score	NN
cord-277648-9kxwkcbl	304	10	(	(	-LRB-
cord-277648-9kxwkcbl	304	11	NES	NES	NNP
cord-277648-9kxwkcbl	304	12	)	)	-RRB-
cord-277648-9kxwkcbl	304	13	and	and	CC
cord-277648-9kxwkcbl	304	14	an	an	DT
cord-277648-9kxwkcbl	304	15	adjusted	adjusted	JJ
cord-277648-9kxwkcbl	304	16	p	p	NN
cord-277648-9kxwkcbl	304	17	-	-	HYPH
cord-277648-9kxwkcbl	304	18	value	value	NN
cord-277648-9kxwkcbl	304	19	,	,	,
cord-277648-9kxwkcbl	304	20	with	with	IN
cord-277648-9kxwkcbl	304	21	a	a	DT
cord-277648-9kxwkcbl	304	22	p<0.05	p<0.05	CD
cord-277648-9kxwkcbl	304	23	significance	significance	NN
cord-277648-9kxwkcbl	304	24	threshold	threshold	NN
cord-277648-9kxwkcbl	304	25	.	.	.
cord-277648-9kxwkcbl	305	1	Pathways	pathway	NNS
cord-277648-9kxwkcbl	305	2	with	with	IN
cord-277648-9kxwkcbl	305	3	positive	positive	JJ
cord-277648-9kxwkcbl	305	4	NES	NES	NNP
cord-277648-9kxwkcbl	305	5	were	be	VBD
cord-277648-9kxwkcbl	305	6	defined	define	VBN
cord-277648-9kxwkcbl	305	7	throughout	throughout	IN
cord-277648-9kxwkcbl	305	8	the	the	DT
cord-277648-9kxwkcbl	305	9	text	text	NN
cord-277648-9kxwkcbl	305	10	as	as	IN
cord-277648-9kxwkcbl	305	11	"	"	``
cord-277648-9kxwkcbl	305	12	enriched	enrich	VBN
cord-277648-9kxwkcbl	305	13	"	"	''
cord-277648-9kxwkcbl	305	14	and	and	CC
cord-277648-9kxwkcbl	305	15	pathways	pathway	NNS
cord-277648-9kxwkcbl	305	16	with	with	IN
cord-277648-9kxwkcbl	305	17	negative	negative	JJ
cord-277648-9kxwkcbl	305	18	NES	NES	NNP
cord-277648-9kxwkcbl	305	19	were	be	VBD
cord-277648-9kxwkcbl	305	20	defined	define	VBN
cord-277648-9kxwkcbl	305	21	as	as	IN
cord-277648-9kxwkcbl	305	22	"	"	``
cord-277648-9kxwkcbl	305	23	depleted	deplete	VBN
cord-277648-9kxwkcbl	305	24	"	"	''
cord-277648-9kxwkcbl	305	25	.	.	.
cord-277648-9kxwkcbl	306	1	Further	further	JJ
cord-277648-9kxwkcbl	306	2	analysis	analysis	NN
cord-277648-9kxwkcbl	306	3	of	of	IN
cord-277648-9kxwkcbl	306	4	significantly	significantly	RB
cord-277648-9kxwkcbl	306	5	differentially	differentially	RB
cord-277648-9kxwkcbl	306	6	expressed	express	VBN
cord-277648-9kxwkcbl	306	7	genes	gene	NNS
cord-277648-9kxwkcbl	306	8	was	be	VBD
cord-277648-9kxwkcbl	306	9	performed	perform	VBN
cord-277648-9kxwkcbl	306	10	using	use	VBG
cord-277648-9kxwkcbl	306	11	the	the	DT
cord-277648-9kxwkcbl	306	12	"	"	``
cord-277648-9kxwkcbl	306	13	EnrichR	EnrichR	NNS
cord-277648-9kxwkcbl	306	14	"	"	''
cord-277648-9kxwkcbl	306	15	(	(	-LRB-
cord-277648-9kxwkcbl	306	16	v.	v.	IN
cord-277648-9kxwkcbl	306	17	2.1	2.1	CD
cord-277648-9kxwkcbl	306	18	)	)	-RRB-
cord-277648-9kxwkcbl	306	19	package	package	NN
cord-277648-9kxwkcbl	306	20	in	in	IN
cord-277648-9kxwkcbl	306	21	R.	R.	NNP
cord-277648-9kxwkcbl	306	22	Gene	Gene	NNP
cord-277648-9kxwkcbl	306	23	ontology	ontology	NN
cord-277648-9kxwkcbl	306	24	(	(	-LRB-
cord-277648-9kxwkcbl	306	25	GO	GO	NNP
cord-277648-9kxwkcbl	306	26	)	)	-RRB-
cord-277648-9kxwkcbl	306	27	analysis	analysis	NN
cord-277648-9kxwkcbl	306	28	was	be	VBD
cord-277648-9kxwkcbl	306	29	conducted	conduct	VBN
cord-277648-9kxwkcbl	306	30	on	on	IN
cord-277648-9kxwkcbl	306	31	the	the	DT
cord-277648-9kxwkcbl	306	32	DEGs	degs	NN
cord-277648-9kxwkcbl	306	33	between	between	IN
cord-277648-9kxwkcbl	306	34	the	the	DT
cord-277648-9kxwkcbl	306	35	severe	severe	JJ
cord-277648-9kxwkcbl	306	36	and	and	CC
cord-277648-9kxwkcbl	306	37	moderate	moderate	JJ
cord-277648-9kxwkcbl	306	38	samples	sample	NNS
cord-277648-9kxwkcbl	306	39	for	for	IN
cord-277648-9kxwkcbl	306	40	both	both	CC
cord-277648-9kxwkcbl	306	41	the	the	DT
cord-277648-9kxwkcbl	306	42	BALF	BALF	NNP
cord-277648-9kxwkcbl	306	43	and	and	CC
cord-277648-9kxwkcbl	306	44	PBMC	PBMC	NNP
cord-277648-9kxwkcbl	306	45	,	,	,
cord-277648-9kxwkcbl	306	46	evaluating	evaluate	VBG
cord-277648-9kxwkcbl	306	47	the	the	DT
cord-277648-9kxwkcbl	306	48	GO	GO	NNP
cord-277648-9kxwkcbl	306	49	"	"	''
cord-277648-9kxwkcbl	306	50	biological	biological	JJ
cord-277648-9kxwkcbl	306	51	function	function	NN
cord-277648-9kxwkcbl	306	52	"	"	''
cord-277648-9kxwkcbl	306	53	annotations	annotation	NNS
cord-277648-9kxwkcbl	306	54	representing	represent	VBG
cord-277648-9kxwkcbl	306	55	large	large	JJ
cord-277648-9kxwkcbl	306	56	scale	scale	NN
cord-277648-9kxwkcbl	306	57	biological	biological	JJ
cord-277648-9kxwkcbl	306	58	programs	program	NNS
cord-277648-9kxwkcbl	306	59	.	.	.
cord-277648-9kxwkcbl	307	1	Transcription	transcription	NN
cord-277648-9kxwkcbl	307	2	factor	factor	NN
cord-277648-9kxwkcbl	307	3	(	(	-LRB-
cord-277648-9kxwkcbl	307	4	TF	TF	NNP
cord-277648-9kxwkcbl	307	5	)	)	-RRB-
cord-277648-9kxwkcbl	307	6	analysis	analysis	NN
cord-277648-9kxwkcbl	307	7	was	be	VBD
cord-277648-9kxwkcbl	307	8	similarly	similarly	RB
cord-277648-9kxwkcbl	307	9	conducted	conduct	VBN
cord-277648-9kxwkcbl	307	10	on	on	IN
cord-277648-9kxwkcbl	307	11	the	the	DT
cord-277648-9kxwkcbl	307	12	DEG	deg	NN
cord-277648-9kxwkcbl	307	13	list	list	NN
cord-277648-9kxwkcbl	307	14	to	to	TO
cord-277648-9kxwkcbl	307	15	query	query	VB
cord-277648-9kxwkcbl	307	16	the	the	DT
cord-277648-9kxwkcbl	307	17	regulation	regulation	NN
cord-277648-9kxwkcbl	307	18	of	of	IN
cord-277648-9kxwkcbl	307	19	TFs	tf	NNS
cord-277648-9kxwkcbl	307	20	identified	identify	VBN
cord-277648-9kxwkcbl	307	21	by	by	IN
cord-277648-9kxwkcbl	307	22	the	the	DT
cord-277648-9kxwkcbl	307	23	ENCODE	ENCODE	NNP
cord-277648-9kxwkcbl	307	24	and	and	CC
cord-277648-9kxwkcbl	307	25	ChEA	ChEA	NNP
cord-277648-9kxwkcbl	307	26	ChIP	ChIP	NNP
cord-277648-9kxwkcbl	307	27	-	-	HYPH
cord-277648-9kxwkcbl	307	28	X	x	NN
cord-277648-9kxwkcbl	307	29	databases	database	NNS
cord-277648-9kxwkcbl	307	30	[	[	-LRB-
cord-277648-9kxwkcbl	307	31	71	71	CD
cord-277648-9kxwkcbl	307	32	,	,	,
cord-277648-9kxwkcbl	307	33	72	72	CD
cord-277648-9kxwkcbl	307	34	]	]	-RRB-
cord-277648-9kxwkcbl	307	35	.	.	.
cord-277648-9kxwkcbl	308	1	GO	go	VB
cord-277648-9kxwkcbl	308	2	and	and	CC
cord-277648-9kxwkcbl	308	3	TF	TF	NNP
cord-277648-9kxwkcbl	308	4	results	result	NNS
cord-277648-9kxwkcbl	308	5	were	be	VBD
cord-277648-9kxwkcbl	308	6	ranked	rank	VBN
cord-277648-9kxwkcbl	308	7	based	base	VBN
cord-277648-9kxwkcbl	308	8	on	on	IN
cord-277648-9kxwkcbl	308	9	the	the	DT
cord-277648-9kxwkcbl	308	10	EnrichR	EnrichR	NNP
cord-277648-9kxwkcbl	308	11	'	'	``
cord-277648-9kxwkcbl	308	12	Combined	combined	JJ
cord-277648-9kxwkcbl	308	13	Score	score	NN
cord-277648-9kxwkcbl	308	14	'	'	''
cord-277648-9kxwkcbl	308	15	metric	metric	JJ
cord-277648-9kxwkcbl	308	16	and	and	CC
cord-277648-9kxwkcbl	308	17	significance	significance	NN
cord-277648-9kxwkcbl	308	18	was	be	VBD
cord-277648-9kxwkcbl	308	19	determined	determine	VBN
cord-277648-9kxwkcbl	308	20	using	use	VBG
cord-277648-9kxwkcbl	308	21	an	an	DT
cord-277648-9kxwkcbl	308	22	adjusted	adjust	VBN
cord-277648-9kxwkcbl	308	23	p	p	NN
cord-277648-9kxwkcbl	308	24	-	-	HYPH
cord-277648-9kxwkcbl	308	25	value	value	NN
cord-277648-9kxwkcbl	308	26	threshold	threshold	NN
cord-277648-9kxwkcbl	308	27	of	of	IN
cord-277648-9kxwkcbl	308	28	p<0.05	p<0.05	CD
cord-277648-9kxwkcbl	308	29	.	.	.
cord-277648-9kxwkcbl	309	1	To	to	TO
cord-277648-9kxwkcbl	309	2	investigate	investigate	VB
cord-277648-9kxwkcbl	309	3	the	the	DT
cord-277648-9kxwkcbl	309	4	intracellular	intracellular	JJ
cord-277648-9kxwkcbl	309	5	interactions	interaction	NNS
cord-277648-9kxwkcbl	309	6	potentially	potentially	RB
cord-277648-9kxwkcbl	309	7	contributing	contribute	VBG
cord-277648-9kxwkcbl	309	8	to	to	IN
cord-277648-9kxwkcbl	309	9	the	the	DT
cord-277648-9kxwkcbl	309	10	observed	observed	JJ
cord-277648-9kxwkcbl	309	11	differential	differential	JJ
cord-277648-9kxwkcbl	309	12	gene	gene	NN
cord-277648-9kxwkcbl	309	13	expression	expression	NN
cord-277648-9kxwkcbl	309	14	between	between	IN
cord-277648-9kxwkcbl	309	15	the	the	DT
cord-277648-9kxwkcbl	309	16	severe	severe	JJ
cord-277648-9kxwkcbl	309	17	and	and	CC
cord-277648-9kxwkcbl	309	18	moderate	moderate	JJ
cord-277648-9kxwkcbl	309	19	sample	sample	NN
cord-277648-9kxwkcbl	309	20	populations	population	NNS
cord-277648-9kxwkcbl	309	21	in	in	IN
cord-277648-9kxwkcbl	309	22	the	the	DT
cord-277648-9kxwkcbl	309	23	BALF	BALF	NNP
cord-277648-9kxwkcbl	309	24	,	,	,
cord-277648-9kxwkcbl	309	25	we	-PRON-	PRP
cord-277648-9kxwkcbl	309	26	employed	employ	VBD
cord-277648-9kxwkcbl	309	27	the	the	DT
cord-277648-9kxwkcbl	309	28	ligand	ligand	NN
cord-277648-9kxwkcbl	309	29	-	-	HYPH
cord-277648-9kxwkcbl	309	30	receptor	receptor	NN
cord-277648-9kxwkcbl	309	31	interaction	interaction	NN
cord-277648-9kxwkcbl	309	32	tool	tool	NN
cord-277648-9kxwkcbl	309	33	NicheNet	NicheNet	NNP
cord-277648-9kxwkcbl	309	34	via	via	IN
cord-277648-9kxwkcbl	309	35	the	the	DT
cord-277648-9kxwkcbl	309	36	"	"	``
cord-277648-9kxwkcbl	309	37	nichenetr	nichenetr	JJ
cord-277648-9kxwkcbl	309	38	"	"	''
cord-277648-9kxwkcbl	309	39	package	package	NN
cord-277648-9kxwkcbl	309	40	(	(	-LRB-
cord-277648-9kxwkcbl	309	41	v.	v.	IN
cord-277648-9kxwkcbl	309	42	0.1.0	0.1.0	NNP
cord-277648-9kxwkcbl	309	43	)	)	-RRB-
cord-277648-9kxwkcbl	309	44	in	in	IN
cord-277648-9kxwkcbl	309	45	R.	R.	NNP
cord-277648-9kxwkcbl	309	46	[	[	-LRB-
cord-277648-9kxwkcbl	309	47	37	37	CD
cord-277648-9kxwkcbl	309	48	]	]	-RRB-
cord-277648-9kxwkcbl	309	49	Differentially	differentially	RB
cord-277648-9kxwkcbl	309	50	expressed	express	VBN
cord-277648-9kxwkcbl	309	51	target	target	NN
cord-277648-9kxwkcbl	309	52	genes	gene	NNS
cord-277648-9kxwkcbl	309	53	between	between	IN
cord-277648-9kxwkcbl	309	54	severe	severe	JJ
cord-277648-9kxwkcbl	309	55	and	and	CC
cord-277648-9kxwkcbl	309	56	moderate	moderate	JJ
cord-277648-9kxwkcbl	309	57	disease	disease	NN
cord-277648-9kxwkcbl	309	58	in	in	IN
cord-277648-9kxwkcbl	309	59	a	a	DT
cord-277648-9kxwkcbl	309	60	"	"	``
cord-277648-9kxwkcbl	309	61	receiver	receiver	NN
cord-277648-9kxwkcbl	309	62	"	"	''
cord-277648-9kxwkcbl	309	63	cell	cell	NN
cord-277648-9kxwkcbl	309	64	population	population	NN
cord-277648-9kxwkcbl	309	65	of	of	IN
cord-277648-9kxwkcbl	309	66	interest	interest	NN
cord-277648-9kxwkcbl	309	67	were	be	VBD
cord-277648-9kxwkcbl	309	68	identified	identify	VBN
cord-277648-9kxwkcbl	309	69	using	use	VBG
cord-277648-9kxwkcbl	309	70	the	the	DT
cord-277648-9kxwkcbl	309	71	'	'	``
cord-277648-9kxwkcbl	309	72	FindMarkers	FindMarkers	NNP
cord-277648-9kxwkcbl	309	73	'	'	POS
cord-277648-9kxwkcbl	309	74	function	function	NN
cord-277648-9kxwkcbl	309	75	in	in	IN
cord-277648-9kxwkcbl	309	76	Seurat	Seurat	NNP
cord-277648-9kxwkcbl	309	77	with	with	IN
cord-277648-9kxwkcbl	309	78	criteria	criterion	NNS
cord-277648-9kxwkcbl	309	79	of	of	IN
cord-277648-9kxwkcbl	309	80	p<0.05	p<0.05	CD
cord-277648-9kxwkcbl	309	81	,	,	,
cord-277648-9kxwkcbl	309	82	average	average	JJ
cord-277648-9kxwkcbl	309	83	natural	natural	JJ
cord-277648-9kxwkcbl	309	84	log	log	NN
cord-277648-9kxwkcbl	309	85	fold	fold	NN
cord-277648-9kxwkcbl	309	86	change	change	NN
cord-277648-9kxwkcbl	309	87	>	>	XX
cord-277648-9kxwkcbl	309	88	0.25	0.25	CD
cord-277648-9kxwkcbl	309	89	,	,	,
cord-277648-9kxwkcbl	309	90	and	and	CC
cord-277648-9kxwkcbl	309	91	expression	expression	NN
cord-277648-9kxwkcbl	309	92	in	in	IN
cord-277648-9kxwkcbl	309	93	over	over	IN
cord-277648-9kxwkcbl	309	94	10	10	CD
cord-277648-9kxwkcbl	309	95	%	%	NN
cord-277648-9kxwkcbl	309	96	of	of	IN
cord-277648-9kxwkcbl	309	97	the	the	DT
cord-277648-9kxwkcbl	309	98	receiver	receiver	NN
cord-277648-9kxwkcbl	309	99	cells	cell	NNS
cord-277648-9kxwkcbl	309	100	.	.	.
cord-277648-9kxwkcbl	310	1	Concurrently	concurrently	RB
cord-277648-9kxwkcbl	310	2	,	,	,
cord-277648-9kxwkcbl	310	3	a	a	DT
cord-277648-9kxwkcbl	310	4	list	list	NN
cord-277648-9kxwkcbl	310	5	of	of	IN
cord-277648-9kxwkcbl	310	6	potential	potential	JJ
cord-277648-9kxwkcbl	310	7	receptors	receptor	NNS
cord-277648-9kxwkcbl	310	8	expressed	express	VBN
cord-277648-9kxwkcbl	310	9	in	in	IN
cord-277648-9kxwkcbl	310	10	over	over	IN
cord-277648-9kxwkcbl	310	11	10	10	CD
cord-277648-9kxwkcbl	310	12	%	%	NN
cord-277648-9kxwkcbl	310	13	of	of	IN
cord-277648-9kxwkcbl	310	14	cells	cell	NNS
cord-277648-9kxwkcbl	310	15	in	in	IN
cord-277648-9kxwkcbl	310	16	the	the	DT
cord-277648-9kxwkcbl	310	17	severe	severe	JJ
cord-277648-9kxwkcbl	310	18	disease	disease	NN
cord-277648-9kxwkcbl	310	19	receiver	receiver	NN
cord-277648-9kxwkcbl	310	20	population	population	NN
cord-277648-9kxwkcbl	310	21	was	be	VBD
cord-277648-9kxwkcbl	310	22	generated	generate	VBN
cord-277648-9kxwkcbl	310	23	using	use	VBG
cord-277648-9kxwkcbl	310	24	NichNet	NichNet	NNP
cord-277648-9kxwkcbl	310	25	.	.	.
cord-277648-9kxwkcbl	311	1	A	a	DT
cord-277648-9kxwkcbl	311	2	list	list	NN
cord-277648-9kxwkcbl	311	3	of	of	IN
cord-277648-9kxwkcbl	311	4	"	"	``
cord-277648-9kxwkcbl	311	5	sender	sender	NN
cord-277648-9kxwkcbl	311	6	"	"	''
cord-277648-9kxwkcbl	311	7	cells	cell	NNS
cord-277648-9kxwkcbl	311	8	was	be	VBD
cord-277648-9kxwkcbl	311	9	created	create	VBN
cord-277648-9kxwkcbl	311	10	comprising	comprise	VBG
cord-277648-9kxwkcbl	311	11	all	all	DT
cord-277648-9kxwkcbl	311	12	cell	cell	NN
cord-277648-9kxwkcbl	311	13	types	type	NNS
cord-277648-9kxwkcbl	311	14	in	in	IN
cord-277648-9kxwkcbl	311	15	the	the	DT
cord-277648-9kxwkcbl	311	16	BALF	BALF	NNP
cord-277648-9kxwkcbl	311	17	,	,	,
cord-277648-9kxwkcbl	311	18	including	include	VBG
cord-277648-9kxwkcbl	311	19	the	the	DT
cord-277648-9kxwkcbl	311	20	receiver	receiver	NN
cord-277648-9kxwkcbl	311	21	cell	cell	NN
cord-277648-9kxwkcbl	311	22	type	type	NN
cord-277648-9kxwkcbl	311	23	to	to	TO
cord-277648-9kxwkcbl	311	24	account	account	VB
cord-277648-9kxwkcbl	311	25	for	for	IN
cord-277648-9kxwkcbl	311	26	the	the	DT
cord-277648-9kxwkcbl	311	27	possibility	possibility	NN
cord-277648-9kxwkcbl	311	28	of	of	IN
cord-277648-9kxwkcbl	311	29	autocrine	autocrine	JJ
cord-277648-9kxwkcbl	311	30	signaling	signaling	NN
cord-277648-9kxwkcbl	311	31	.	.	.
cord-277648-9kxwkcbl	312	1	For	for	IN
cord-277648-9kxwkcbl	312	2	each	each	DT
cord-277648-9kxwkcbl	312	3	sender	sender	NN
cord-277648-9kxwkcbl	312	4	cell	cell	NN
cord-277648-9kxwkcbl	312	5	population	population	NN
cord-277648-9kxwkcbl	312	6	,	,	,
cord-277648-9kxwkcbl	312	7	potential	potential	JJ
cord-277648-9kxwkcbl	312	8	ligands	ligand	NNS
cord-277648-9kxwkcbl	312	9	were	be	VBD
cord-277648-9kxwkcbl	312	10	inferred	infer	VBN
cord-277648-9kxwkcbl	312	11	using	use	VBG
cord-277648-9kxwkcbl	312	12	the	the	DT
cord-277648-9kxwkcbl	312	13	NichNet	NichNet	NNP
cord-277648-9kxwkcbl	312	14	ligand	ligand	NN
cord-277648-9kxwkcbl	312	15	-	-	HYPH
cord-277648-9kxwkcbl	312	16	receptor	receptor	NN
cord-277648-9kxwkcbl	312	17	network	network	NN
cord-277648-9kxwkcbl	312	18	applied	apply	VBN
cord-277648-9kxwkcbl	312	19	to	to	IN
cord-277648-9kxwkcbl	312	20	genes	gene	NNS
cord-277648-9kxwkcbl	312	21	expressed	express	VBN
cord-277648-9kxwkcbl	312	22	in	in	IN
cord-277648-9kxwkcbl	312	23	over	over	IN
cord-277648-9kxwkcbl	312	24	10	10	CD
cord-277648-9kxwkcbl	312	25	%	%	NN
cord-277648-9kxwkcbl	312	26	of	of	IN
cord-277648-9kxwkcbl	312	27	the	the	DT
cord-277648-9kxwkcbl	312	28	severe	severe	JJ
cord-277648-9kxwkcbl	312	29	disease	disease	NN
cord-277648-9kxwkcbl	312	30	sender	sender	NN
cord-277648-9kxwkcbl	312	31	population	population	NN
cord-277648-9kxwkcbl	312	32	.	.	.
cord-277648-9kxwkcbl	313	1	Ligand	ligand	NN
cord-277648-9kxwkcbl	313	2	activities	activity	NNS
cord-277648-9kxwkcbl	313	3	were	be	VBD
cord-277648-9kxwkcbl	313	4	predicted	predict	VBN
cord-277648-9kxwkcbl	313	5	using	use	VBG
cord-277648-9kxwkcbl	313	6	the	the	DT
cord-277648-9kxwkcbl	313	7	'	'	``
cord-277648-9kxwkcbl	313	8	predict_ligand_activities	predict_ligand_activitie	NNS
cord-277648-9kxwkcbl	313	9	'	'	POS
cord-277648-9kxwkcbl	313	10	function	function	NN
cord-277648-9kxwkcbl	313	11	in	in	IN
cord-277648-9kxwkcbl	313	12	NicheNet	NicheNet	NNP
cord-277648-9kxwkcbl	313	13	,	,	,
cord-277648-9kxwkcbl	313	14	and	and	CC
cord-277648-9kxwkcbl	313	15	the	the	DT
cord-277648-9kxwkcbl	313	16	top	top	JJ
cord-277648-9kxwkcbl	313	17	20	20	CD
cord-277648-9kxwkcbl	313	18	ligands	ligand	NNS
cord-277648-9kxwkcbl	313	19	were	be	VBD
cord-277648-9kxwkcbl	313	20	selected	select	VBN
cord-277648-9kxwkcbl	313	21	by	by	IN
cord-277648-9kxwkcbl	313	22	Pearson	Pearson	NNP
cord-277648-9kxwkcbl	313	23	correlation	correlation	NN
cord-277648-9kxwkcbl	313	24	coefficient	coefficient	NN
cord-277648-9kxwkcbl	313	25	.	.	.
cord-277648-9kxwkcbl	314	1	Differentially	differentially	RB
cord-277648-9kxwkcbl	314	2	expressed	express	VBN
cord-277648-9kxwkcbl	314	3	target	target	NN
cord-277648-9kxwkcbl	314	4	genes	gene	NNS
cord-277648-9kxwkcbl	314	5	ranking	rank	VBG
cord-277648-9kxwkcbl	314	6	among	among	IN
cord-277648-9kxwkcbl	314	7	the	the	DT
cord-277648-9kxwkcbl	314	8	100	100	CD
cord-277648-9kxwkcbl	314	9	most	most	RBS
cord-277648-9kxwkcbl	314	10	strongly	strongly	RB
cord-277648-9kxwkcbl	314	11	predicted	predict	VBD
cord-277648-9kxwkcbl	314	12	targets	target	NNS
cord-277648-9kxwkcbl	314	13	of	of	IN
cord-277648-9kxwkcbl	314	14	the	the	DT
cord-277648-9kxwkcbl	314	15	top	top	JJ
cord-277648-9kxwkcbl	314	16	20	20	CD
cord-277648-9kxwkcbl	314	17	ligands	ligand	NNS
cord-277648-9kxwkcbl	314	18	were	be	VBD
cord-277648-9kxwkcbl	314	19	given	give	VBN
cord-277648-9kxwkcbl	314	20	a	a	DT
cord-277648-9kxwkcbl	314	21	"	"	``
cord-277648-9kxwkcbl	314	22	regulatory	regulatory	JJ
cord-277648-9kxwkcbl	314	23	potential	potential	NN
cord-277648-9kxwkcbl	314	24	"	"	''
cord-277648-9kxwkcbl	314	25	interaction	interaction	NN
cord-277648-9kxwkcbl	314	26	score	score	NN
cord-277648-9kxwkcbl	314	27	.	.	.
cord-277648-9kxwkcbl	315	1	The	the	DT
cord-277648-9kxwkcbl	315	2	upper	upper	JJ
cord-277648-9kxwkcbl	315	3	50	50	CD
cord-277648-9kxwkcbl	315	4	%	%	NN
cord-277648-9kxwkcbl	315	5	of	of	IN
cord-277648-9kxwkcbl	315	6	targets	target	NNS
cord-277648-9kxwkcbl	315	7	by	by	IN
cord-277648-9kxwkcbl	315	8	regulatory	regulatory	JJ
cord-277648-9kxwkcbl	315	9	potential	potential	NN
cord-277648-9kxwkcbl	315	10	were	be	VBD
cord-277648-9kxwkcbl	315	11	visualized	visualize	VBN
cord-277648-9kxwkcbl	315	12	for	for	IN
cord-277648-9kxwkcbl	315	13	plasmacytoid	plasmacytoid	NNP
cord-277648-9kxwkcbl	315	14	dendritic	dendritic	JJ
cord-277648-9kxwkcbl	315	15	cells	cell	NNS
cord-277648-9kxwkcbl	315	16	(	(	-LRB-
cord-277648-9kxwkcbl	315	17	pDCs	pDCs	NNP
cord-277648-9kxwkcbl	315	18	)	)	-RRB-
cord-277648-9kxwkcbl	315	19	,	,	,
cord-277648-9kxwkcbl	315	20	and	and	CC
cord-277648-9kxwkcbl	315	21	the	the	DT
cord-277648-9kxwkcbl	315	22	upper	upper	JJ
cord-277648-9kxwkcbl	315	23	15	15	CD
cord-277648-9kxwkcbl	315	24	%	%	NN
cord-277648-9kxwkcbl	315	25	of	of	IN
cord-277648-9kxwkcbl	315	26	targets	target	NNS
cord-277648-9kxwkcbl	315	27	were	be	VBD
cord-277648-9kxwkcbl	315	28	visualized	visualize	VBN
cord-277648-9kxwkcbl	315	29	for	for	IN
cord-277648-9kxwkcbl	315	30	epithelial	epithelial	JJ
cord-277648-9kxwkcbl	315	31	cells	cell	NNS
cord-277648-9kxwkcbl	315	32	(	(	-LRB-
cord-277648-9kxwkcbl	315	33	ciliated	ciliated	JJ
cord-277648-9kxwkcbl	315	34	cells	cell	NNS
cord-277648-9kxwkcbl	315	35	and	and	CC
cord-277648-9kxwkcbl	315	36	club	club	NN
cord-277648-9kxwkcbl	315	37	cells	cell	NNS
cord-277648-9kxwkcbl	315	38	)	)	-RRB-
cord-277648-9kxwkcbl	315	39	.	.	.
cord-277648-9kxwkcbl	316	1	To	to	TO
cord-277648-9kxwkcbl	316	2	specifically	specifically	RB
cord-277648-9kxwkcbl	316	3	analyze	analyze	VB
cord-277648-9kxwkcbl	316	4	signaling	signal	VBG
cord-277648-9kxwkcbl	316	5	from	from	IN
cord-277648-9kxwkcbl	316	6	mononuclear	mononuclear	JJ
cord-277648-9kxwkcbl	316	7	phagocytes	phagocyte	NNS
cord-277648-9kxwkcbl	316	8	and	and	CC
cord-277648-9kxwkcbl	316	9	neutrophils	neutrophil	NNS
cord-277648-9kxwkcbl	316	10	,	,	,
cord-277648-9kxwkcbl	316	11	differentially	differentially	RB
cord-277648-9kxwkcbl	316	12	expressed	express	VBN
cord-277648-9kxwkcbl	316	13	target	target	NN
cord-277648-9kxwkcbl	316	14	genes	gene	NNS
cord-277648-9kxwkcbl	316	15	ranking	rank	VBG
cord-277648-9kxwkcbl	316	16	among	among	IN
cord-277648-9kxwkcbl	316	17	the	the	DT
cord-277648-9kxwkcbl	316	18	250	250	CD
cord-277648-9kxwkcbl	316	19	most	most	RBS
cord-277648-9kxwkcbl	316	20	strongly	strongly	RB
cord-277648-9kxwkcbl	316	21	predicted	predict	VBD
cord-277648-9kxwkcbl	316	22	targets	target	NNS
cord-277648-9kxwkcbl	316	23	of	of	IN
cord-277648-9kxwkcbl	316	24	the	the	DT
cord-277648-9kxwkcbl	316	25	top	top	JJ
cord-277648-9kxwkcbl	316	26	20	20	CD
cord-277648-9kxwkcbl	316	27	ligands	ligand	NNS
cord-277648-9kxwkcbl	316	28	were	be	VBD
cord-277648-9kxwkcbl	316	29	used	use	VBN
cord-277648-9kxwkcbl	316	30	,	,	,
cord-277648-9kxwkcbl	316	31	with	with	IN
cord-277648-9kxwkcbl	316	32	the	the	DT
cord-277648-9kxwkcbl	316	33	upper	upper	JJ
cord-277648-9kxwkcbl	316	34	25	25	CD
cord-277648-9kxwkcbl	316	35	%	%	NN
cord-277648-9kxwkcbl	316	36	of	of	IN
cord-277648-9kxwkcbl	316	37	these	these	DT
cord-277648-9kxwkcbl	316	38	targets	target	NNS
cord-277648-9kxwkcbl	316	39	according	accord	VBG
cord-277648-9kxwkcbl	316	40	to	to	IN
cord-277648-9kxwkcbl	316	41	regulatory	regulatory	JJ
cord-277648-9kxwkcbl	316	42	potential	potential	NN
cord-277648-9kxwkcbl	316	43	visualized	visualize	VBN
cord-277648-9kxwkcbl	316	44	in	in	IN
cord-277648-9kxwkcbl	316	45	circos	circos	NNP
cord-277648-9kxwkcbl	316	46	plots	plot	NNS
cord-277648-9kxwkcbl	316	47	.	.	.
cord-277648-9kxwkcbl	317	1	Non	non	JJ
cord-277648-9kxwkcbl	317	2	-	-	JJ
cord-277648-9kxwkcbl	317	3	signaling	signal	VBG
cord-277648-9kxwkcbl	317	4	molecules	molecule	NNS
cord-277648-9kxwkcbl	317	5	and	and	CC
cord-277648-9kxwkcbl	317	6	molecules	molecule	NNS
cord-277648-9kxwkcbl	317	7	acting	act	VBG
cord-277648-9kxwkcbl	317	8	on	on	IN
cord-277648-9kxwkcbl	317	9	non	non	JJ
cord-277648-9kxwkcbl	317	10	-	-	JJ
cord-277648-9kxwkcbl	317	11	coding	coding	JJ
cord-277648-9kxwkcbl	317	12	RNA	RNA	NNP
cord-277648-9kxwkcbl	317	13	targets	target	NNS
cord-277648-9kxwkcbl	317	14	were	be	VBD
cord-277648-9kxwkcbl	317	15	manually	manually	RB
cord-277648-9kxwkcbl	317	16	removed	remove	VBN
cord-277648-9kxwkcbl	317	17	.	.	.
cord-277648-9kxwkcbl	318	1	Receptors	receptor	NNS
cord-277648-9kxwkcbl	318	2	for	for	IN
cord-277648-9kxwkcbl	318	3	the	the	DT
cord-277648-9kxwkcbl	318	4	top	top	JJ
cord-277648-9kxwkcbl	318	5	20	20	CD
cord-277648-9kxwkcbl	318	6	ligands	ligand	NNS
cord-277648-9kxwkcbl	318	7	were	be	VBD
cord-277648-9kxwkcbl	318	8	identified	identify	VBN
cord-277648-9kxwkcbl	318	9	using	use	VBG
cord-277648-9kxwkcbl	318	10	the	the	DT
cord-277648-9kxwkcbl	318	11	CellPhoneDB	CellPhoneDB	NNP
cord-277648-9kxwkcbl	318	12	web	web	NN
cord-277648-9kxwkcbl	318	13	server	server	NN
cord-277648-9kxwkcbl	318	14	[	[	-LRB-
cord-277648-9kxwkcbl	318	15	73	73	CD
cord-277648-9kxwkcbl	318	16	]	]	-RRB-
cord-277648-9kxwkcbl	318	17	,	,	,
cord-277648-9kxwkcbl	318	18	and	and	CC
cord-277648-9kxwkcbl	318	19	non	non	JJ
cord-277648-9kxwkcbl	318	20	-	-	JJ
cord-277648-9kxwkcbl	318	21	zero	zero	JJ
cord-277648-9kxwkcbl	318	22	expression	expression	NN
cord-277648-9kxwkcbl	318	23	was	be	VBD
cord-277648-9kxwkcbl	318	24	verified	verify	VBN
cord-277648-9kxwkcbl	318	25	in	in	IN
cord-277648-9kxwkcbl	318	26	the	the	DT
cord-277648-9kxwkcbl	318	27	severe	severe	JJ
cord-277648-9kxwkcbl	318	28	disease	disease	NN
cord-277648-9kxwkcbl	318	29	receiver	receiver	NN
cord-277648-9kxwkcbl	318	30	cell	cell	NN
cord-277648-9kxwkcbl	318	31	population	population	NN
cord-277648-9kxwkcbl	318	32	of	of	IN
cord-277648-9kxwkcbl	318	33	interest	interest	NN
cord-277648-9kxwkcbl	318	34	using	use	VBG
cord-277648-9kxwkcbl	318	35	Seurat	Seurat	NNP
cord-277648-9kxwkcbl	318	36	.	.	.
cord-277648-9kxwkcbl	319	1	Identification	identification	NN
cord-277648-9kxwkcbl	319	2	of	of	IN
cord-277648-9kxwkcbl	319	3	potential	potential	JJ
cord-277648-9kxwkcbl	319	4	broadly	broadly	RB
cord-277648-9kxwkcbl	319	5	acting	act	VBG
cord-277648-9kxwkcbl	319	6	"	"	``
cord-277648-9kxwkcbl	319	7	pan	pan	NN
cord-277648-9kxwkcbl	319	8	-	-	HYPH
cord-277648-9kxwkcbl	319	9	ligands	ligand	NNS
cord-277648-9kxwkcbl	319	10	"	"	''
cord-277648-9kxwkcbl	319	11	was	be	VBD
cord-277648-9kxwkcbl	319	12	conducted	conduct	VBN
cord-277648-9kxwkcbl	319	13	by	by	IN
cord-277648-9kxwkcbl	319	14	replicating	replicate	VBG
cord-277648-9kxwkcbl	319	15	the	the	DT
cord-277648-9kxwkcbl	319	16	above	above	JJ
cord-277648-9kxwkcbl	319	17	NicheNet	NicheNet	NNP
cord-277648-9kxwkcbl	319	18	procedure	procedure	NN
cord-277648-9kxwkcbl	319	19	iteratively	iteratively	RB
cord-277648-9kxwkcbl	319	20	using	use	VBG
cord-277648-9kxwkcbl	319	21	each	each	DT
cord-277648-9kxwkcbl	319	22	cell	cell	NN
cord-277648-9kxwkcbl	319	23	type	type	NN
cord-277648-9kxwkcbl	319	24	of	of	IN
cord-277648-9kxwkcbl	319	25	the	the	DT
cord-277648-9kxwkcbl	319	26	BALF	BALF	NNP
cord-277648-9kxwkcbl	319	27	as	as	IN
cord-277648-9kxwkcbl	319	28	a	a	DT
cord-277648-9kxwkcbl	319	29	receiver	receiver	NN
cord-277648-9kxwkcbl	319	30	.	.	.
cord-277648-9kxwkcbl	320	1	For	for	IN
cord-277648-9kxwkcbl	320	2	each	each	DT
cord-277648-9kxwkcbl	320	3	receiver	receiver	NN
cord-277648-9kxwkcbl	320	4	cell	cell	NN
cord-277648-9kxwkcbl	320	5	type	type	NN
cord-277648-9kxwkcbl	320	6	,	,	,
cord-277648-9kxwkcbl	320	7	ligands	ligand	NNS
cord-277648-9kxwkcbl	320	8	with	with	IN
cord-277648-9kxwkcbl	320	9	positive	positive	JJ
cord-277648-9kxwkcbl	320	10	Pearson	Pearson	NNP
cord-277648-9kxwkcbl	320	11	correlation	correlation	NN
cord-277648-9kxwkcbl	320	12	were	be	VBD
cord-277648-9kxwkcbl	320	13	filtered	filter	VBN
cord-277648-9kxwkcbl	320	14	based	base	VBN
cord-277648-9kxwkcbl	320	15	on	on	IN
cord-277648-9kxwkcbl	320	16	1	1	CD
cord-277648-9kxwkcbl	320	17	)	)	-RRB-
cord-277648-9kxwkcbl	320	18	either	either	CC
cord-277648-9kxwkcbl	320	19	belonging	belong	VBG
cord-277648-9kxwkcbl	320	20	to	to	IN
cord-277648-9kxwkcbl	320	21	the	the	DT
cord-277648-9kxwkcbl	320	22	list	list	NN
cord-277648-9kxwkcbl	320	23	of	of	IN
cord-277648-9kxwkcbl	320	24	top	top	JJ
cord-277648-9kxwkcbl	320	25	20	20	CD
cord-277648-9kxwkcbl	320	26	ligands	ligand	NNS
cord-277648-9kxwkcbl	320	27	or	or	CC
cord-277648-9kxwkcbl	320	28	having	have	VBG
cord-277648-9kxwkcbl	320	29	a	a	DT
cord-277648-9kxwkcbl	320	30	Pearson	Pearson	NNP
cord-277648-9kxwkcbl	320	31	correlation	correlation	NN
cord-277648-9kxwkcbl	320	32	greater	great	JJR
cord-277648-9kxwkcbl	320	33	than	than	IN
cord-277648-9kxwkcbl	320	34	0.1	0.1	CD
cord-277648-9kxwkcbl	320	35	,	,	,
cord-277648-9kxwkcbl	320	36	and	and	CC
cord-277648-9kxwkcbl	320	37	2	2	LS
cord-277648-9kxwkcbl	320	38	)	)	-RRB-
cord-277648-9kxwkcbl	320	39	presence	presence	NN
cord-277648-9kxwkcbl	320	40	of	of	IN
cord-277648-9kxwkcbl	320	41	the	the	DT
cord-277648-9kxwkcbl	320	42	corresponding	corresponding	JJ
cord-277648-9kxwkcbl	320	43	receptor	receptor	NN
cord-277648-9kxwkcbl	320	44	in	in	IN
cord-277648-9kxwkcbl	320	45	over	over	IN
cord-277648-9kxwkcbl	320	46	10	10	CD
cord-277648-9kxwkcbl	320	47	%	%	NN
cord-277648-9kxwkcbl	320	48	of	of	IN
cord-277648-9kxwkcbl	320	49	cells	cell	NNS
cord-277648-9kxwkcbl	320	50	(	(	-LRB-
cord-277648-9kxwkcbl	320	51	manually	manually	RB
cord-277648-9kxwkcbl	320	52	validated	validate	VBN
cord-277648-9kxwkcbl	320	53	using	use	VBG
cord-277648-9kxwkcbl	320	54	CellPhoneDB	CellPhoneDB	NNP
cord-277648-9kxwkcbl	320	55	[	[	-LRB-
cord-277648-9kxwkcbl	320	56	73	73	CD
cord-277648-9kxwkcbl	320	57	]	]	-RRB-
cord-277648-9kxwkcbl	320	58	)	)	-RRB-
cord-277648-9kxwkcbl	320	59	.	.	.
cord-277648-9kxwkcbl	321	1	Only	only	RB
cord-277648-9kxwkcbl	321	2	ligands	ligand	NNS
cord-277648-9kxwkcbl	321	3	meeting	meet	VBG
cord-277648-9kxwkcbl	321	4	these	these	DT
cord-277648-9kxwkcbl	321	5	criteria	criterion	NNS
cord-277648-9kxwkcbl	321	6	for	for	IN
cord-277648-9kxwkcbl	321	7	over	over	IN
cord-277648-9kxwkcbl	321	8	one	one	CD
cord-277648-9kxwkcbl	321	9	-	-	HYPH
cord-277648-9kxwkcbl	321	10	third	third	NN
cord-277648-9kxwkcbl	321	11	of	of	IN
cord-277648-9kxwkcbl	321	12	cell	cell	NN
cord-277648-9kxwkcbl	321	13	types	type	NNS
cord-277648-9kxwkcbl	321	14	in	in	IN
cord-277648-9kxwkcbl	321	15	the	the	DT
cord-277648-9kxwkcbl	321	16	BALF	BALF	NNP
cord-277648-9kxwkcbl	321	17	were	be	VBD
cord-277648-9kxwkcbl	321	18	preserved	preserve	VBN
cord-277648-9kxwkcbl	321	19	for	for	IN
cord-277648-9kxwkcbl	321	20	further	further	JJ
cord-277648-9kxwkcbl	321	21	analysis	analysis	NN
cord-277648-9kxwkcbl	321	22	.	.	.
cord-277648-9kxwkcbl	322	1	Of	of	IN
cord-277648-9kxwkcbl	322	2	these	these	DT
cord-277648-9kxwkcbl	322	3	,	,	,
cord-277648-9kxwkcbl	322	4	the	the	DT
cord-277648-9kxwkcbl	322	5	ligands	ligand	NNS
cord-277648-9kxwkcbl	322	6	differentially	differentially	RB
cord-277648-9kxwkcbl	322	7	expressed	express	VBN
cord-277648-9kxwkcbl	322	8	in	in	IN
cord-277648-9kxwkcbl	322	9	severe	severe	JJ
cord-277648-9kxwkcbl	322	10	disease	disease	NN
cord-277648-9kxwkcbl	322	11	compared	compare	VBN
cord-277648-9kxwkcbl	322	12	to	to	IN
cord-277648-9kxwkcbl	322	13	moderate	moderate	JJ
cord-277648-9kxwkcbl	322	14	disease	disease	NN
cord-277648-9kxwkcbl	322	15	in	in	IN
cord-277648-9kxwkcbl	322	16	at	at	RB
cord-277648-9kxwkcbl	322	17	least	least	RBS
cord-277648-9kxwkcbl	322	18	one	one	CD
cord-277648-9kxwkcbl	322	19	BALF	BALF	NNP
cord-277648-9kxwkcbl	322	20	cell	cell	NN
cord-277648-9kxwkcbl	322	21	type	type	NN
cord-277648-9kxwkcbl	322	22	were	be	VBD
cord-277648-9kxwkcbl	322	23	classified	classify	VBN
cord-277648-9kxwkcbl	322	24	as	as	IN
cord-277648-9kxwkcbl	322	25	potential	potential	JJ
cord-277648-9kxwkcbl	322	26	pan	pan	NN
cord-277648-9kxwkcbl	322	27	-	-	NNS
cord-277648-9kxwkcbl	322	28	ligands	ligand	NNS
cord-277648-9kxwkcbl	322	29	.	.	.
cord-277648-9kxwkcbl	323	1	Differential	differential	JJ
cord-277648-9kxwkcbl	323	2	gene	gene	NN
cord-277648-9kxwkcbl	323	3	expression	expression	NN
cord-277648-9kxwkcbl	323	4	was	be	VBD
cord-277648-9kxwkcbl	323	5	analyzed	analyze	VBN
cord-277648-9kxwkcbl	323	6	using	use	VBG
cord-277648-9kxwkcbl	323	7	the	the	DT
cord-277648-9kxwkcbl	323	8	"	"	``
cord-277648-9kxwkcbl	323	9	MAST	MAST	NNP
cord-277648-9kxwkcbl	323	10	"	"	''
cord-277648-9kxwkcbl	323	11	package	package	NN
cord-277648-9kxwkcbl	323	12	statistical	statistical	JJ
cord-277648-9kxwkcbl	323	13	framework	framework	NN
cord-277648-9kxwkcbl	323	14	through	through	IN
cord-277648-9kxwkcbl	323	15	the	the	DT
cord-277648-9kxwkcbl	323	16	'	'	``
cord-277648-9kxwkcbl	323	17	FindMarkers	FindMarkers	NNP
cord-277648-9kxwkcbl	323	18	'	'	POS
cord-277648-9kxwkcbl	323	19	function	function	NN
cord-277648-9kxwkcbl	323	20	in	in	IN
cord-277648-9kxwkcbl	323	21	Seurat	Seurat	NNP
cord-277648-9kxwkcbl	323	22	.	.	.
cord-277648-9kxwkcbl	324	1	Differential	differential	JJ
cord-277648-9kxwkcbl	324	2	expression	expression	NN
cord-277648-9kxwkcbl	324	3	statistical	statistical	JJ
cord-277648-9kxwkcbl	324	4	significance	significance	NN
cord-277648-9kxwkcbl	324	5	was	be	VBD
cord-277648-9kxwkcbl	324	6	qualified	qualify	VBN
cord-277648-9kxwkcbl	324	7	using	use	VBG
cord-277648-9kxwkcbl	324	8	the	the	DT
cord-277648-9kxwkcbl	324	9	MAST	mast	JJ
cord-277648-9kxwkcbl	324	10	false	false	JJ
cord-277648-9kxwkcbl	324	11	discovery	discovery	NN
cord-277648-9kxwkcbl	324	12	rate	rate	NN
cord-277648-9kxwkcbl	324	13	(	(	-LRB-
cord-277648-9kxwkcbl	324	14	FDR	FDR	NNP
cord-277648-9kxwkcbl	324	15	)	)	-RRB-
cord-277648-9kxwkcbl	324	16	adjusted	adjust	VBN
cord-277648-9kxwkcbl	324	17	p	p	NN
cord-277648-9kxwkcbl	324	18	-	-	HYPH
cord-277648-9kxwkcbl	324	19	value	value	NN
cord-277648-9kxwkcbl	324	20	,	,	,
cord-277648-9kxwkcbl	324	21	with	with	IN
cord-277648-9kxwkcbl	324	22	a	a	DT
cord-277648-9kxwkcbl	324	23	significance	significance	NN
cord-277648-9kxwkcbl	324	24	threshold	threshold	NN
cord-277648-9kxwkcbl	324	25	of	of	IN
cord-277648-9kxwkcbl	324	26	p<0.05	p<0.05	CD
cord-277648-9kxwkcbl	324	27	.	.	.
cord-277648-9kxwkcbl	325	1	Pathway	pathway	NN
cord-277648-9kxwkcbl	325	2	enrichment	enrichment	NN
cord-277648-9kxwkcbl	325	3	was	be	VBD
cord-277648-9kxwkcbl	325	4	analyzed	analyze	VBN
cord-277648-9kxwkcbl	325	5	using	use	VBG
cord-277648-9kxwkcbl	325	6	the	the	DT
cord-277648-9kxwkcbl	325	7	standard	standard	JJ
cord-277648-9kxwkcbl	325	8	GSEA	GSEA	NNP
cord-277648-9kxwkcbl	325	9	method	method	NN
cord-277648-9kxwkcbl	325	10	in	in	IN
cord-277648-9kxwkcbl	325	11	the	the	DT
cord-277648-9kxwkcbl	325	12	"	"	``
cord-277648-9kxwkcbl	325	13	fgsea	fgsea	NN
cord-277648-9kxwkcbl	325	14	"	"	''
cord-277648-9kxwkcbl	325	15	package	package	NN
cord-277648-9kxwkcbl	325	16	.	.	.
cord-277648-9kxwkcbl	326	1	Statistical	statistical	JJ
cord-277648-9kxwkcbl	326	2	significance	significance	NN
cord-277648-9kxwkcbl	326	3	of	of	IN
cord-277648-9kxwkcbl	326	4	normalized	normalized	JJ
cord-277648-9kxwkcbl	326	5	enrichment	enrichment	NN
cord-277648-9kxwkcbl	326	6	scores	score	NNS
cord-277648-9kxwkcbl	326	7	was	be	VBD
cord-277648-9kxwkcbl	326	8	qualified	qualify	VBN
cord-277648-9kxwkcbl	326	9	using	use	VBG
cord-277648-9kxwkcbl	326	10	the	the	DT
cord-277648-9kxwkcbl	326	11	fgsea	fgsea	NN
cord-277648-9kxwkcbl	327	1	FDR	FDR	NNP
cord-277648-9kxwkcbl	327	2	adjusted	adjust	VBD
cord-277648-9kxwkcbl	327	3	p	p	NN
cord-277648-9kxwkcbl	327	4	-	-	HYPH
cord-277648-9kxwkcbl	327	5	value	value	NN
cord-277648-9kxwkcbl	327	6	,	,	,
cord-277648-9kxwkcbl	327	7	with	with	IN
cord-277648-9kxwkcbl	327	8	a	a	DT
cord-277648-9kxwkcbl	327	9	significance	significance	NN
cord-277648-9kxwkcbl	327	10	threshold	threshold	NN
cord-277648-9kxwkcbl	327	11	of	of	IN
cord-277648-9kxwkcbl	327	12	p<0.05	p<0.05	CD
cord-277648-9kxwkcbl	327	13	.	.	.
cord-277648-9kxwkcbl	328	1	Differential	differential	JJ
cord-277648-9kxwkcbl	328	2	gene	gene	NN
cord-277648-9kxwkcbl	328	3	expression	expression	NN
cord-277648-9kxwkcbl	328	4	relevant	relevant	JJ
cord-277648-9kxwkcbl	328	5	to	to	IN
cord-277648-9kxwkcbl	328	6	ligand	ligand	NN
cord-277648-9kxwkcbl	328	7	-	-	HYPH
cord-277648-9kxwkcbl	328	8	receptor	receptor	NN
cord-277648-9kxwkcbl	328	9	interactions	interaction	NNS
cord-277648-9kxwkcbl	328	10	was	be	VBD
cord-277648-9kxwkcbl	328	11	evaluated	evaluate	VBN
cord-277648-9kxwkcbl	328	12	using	use	VBG
cord-277648-9kxwkcbl	328	13	the	the	DT
cord-277648-9kxwkcbl	328	14	NichNet	NichNet	NNP
cord-277648-9kxwkcbl	328	15	pipeline	pipeline	NN
cord-277648-9kxwkcbl	328	16	implementing	implement	VBG
cord-277648-9kxwkcbl	328	17	the	the	DT
cord-277648-9kxwkcbl	328	18	Wilcoxon	Wilcoxon	NNP
cord-277648-9kxwkcbl	328	19	rank	rank	NN
cord-277648-9kxwkcbl	328	20	sum	sum	NN
cord-277648-9kxwkcbl	328	21	test	test	NN
cord-277648-9kxwkcbl	328	22	through	through	IN
cord-277648-9kxwkcbl	328	23	the	the	DT
cord-277648-9kxwkcbl	328	24	'	'	``
cord-277648-9kxwkcbl	328	25	FindMarkers	FindMarkers	NNP
cord-277648-9kxwkcbl	328	26	'	'	POS
cord-277648-9kxwkcbl	328	27	function	function	NN
cord-277648-9kxwkcbl	328	28	in	in	IN
cord-277648-9kxwkcbl	328	29	Seurat	Seurat	NNP
cord-277648-9kxwkcbl	328	30	.	.	.
cord-277648-9kxwkcbl	329	1	Statistical	statistical	JJ
cord-277648-9kxwkcbl	329	2	significance	significance	NN
cord-277648-9kxwkcbl	329	3	was	be	VBD
cord-277648-9kxwkcbl	329	4	qualified	qualify	VBN
cord-277648-9kxwkcbl	329	5	using	use	VBG
cord-277648-9kxwkcbl	329	6	the	the	DT
cord-277648-9kxwkcbl	329	7	'	'	``
cord-277648-9kxwkcbl	329	8	FindMarkers	FindMarkers	NNP
cord-277648-9kxwkcbl	329	9	'	'	''
cord-277648-9kxwkcbl	329	10	Bonferroni	Bonferroni	NNP
cord-277648-9kxwkcbl	329	11	-	-	HYPH
cord-277648-9kxwkcbl	329	12	adjusted	adjust	VBN
cord-277648-9kxwkcbl	329	13	pvalue	pvalue	NNS
cord-277648-9kxwkcbl	329	14	,	,	,
cord-277648-9kxwkcbl	329	15	with	with	IN
cord-277648-9kxwkcbl	329	16	a	a	DT
cord-277648-9kxwkcbl	329	17	significance	significance	NN
cord-277648-9kxwkcbl	329	18	threshold	threshold	NN
cord-277648-9kxwkcbl	329	19	of	of	IN
cord-277648-9kxwkcbl	329	20	p<0.05	p<0.05	CD
cord-277648-9kxwkcbl	329	21	.	.	.
cord-277648-9kxwkcbl	330	1	GO	go	VB
cord-277648-9kxwkcbl	330	2	and	and	CC
cord-277648-9kxwkcbl	330	3	TF	TF	NNP
cord-277648-9kxwkcbl	330	4	analysis	analysis	NN
cord-277648-9kxwkcbl	330	5	was	be	VBD
cord-277648-9kxwkcbl	330	6	conducted	conduct	VBN
cord-277648-9kxwkcbl	330	7	using	use	VBG
cord-277648-9kxwkcbl	330	8	the	the	DT
cord-277648-9kxwkcbl	330	9	"	"	``
cord-277648-9kxwkcbl	330	10	EnrichR	EnrichR	NNP
cord-277648-9kxwkcbl	330	11	"	"	''
cord-277648-9kxwkcbl	330	12	package	package	NN
cord-277648-9kxwkcbl	330	13	,	,	,
cord-277648-9kxwkcbl	330	14	and	and	CC
cord-277648-9kxwkcbl	330	15	statistical	statistical	JJ
cord-277648-9kxwkcbl	330	16	significance	significance	NN
cord-277648-9kxwkcbl	330	17	was	be	VBD
cord-277648-9kxwkcbl	330	18	qualified	qualify	VBN
cord-277648-9kxwkcbl	330	19	using	use	VBG
cord-277648-9kxwkcbl	330	20	the	the	DT
cord-277648-9kxwkcbl	330	21	EnrichR	EnrichR	NNP
cord-277648-9kxwkcbl	330	22	adjusted	adjust	VBN
cord-277648-9kxwkcbl	330	23	p	p	NN
cord-277648-9kxwkcbl	330	24	-	-	HYPH
cord-277648-9kxwkcbl	330	25	value	value	NN
cord-277648-9kxwkcbl	330	26	based	base	VBN
cord-277648-9kxwkcbl	330	27	on	on	IN
cord-277648-9kxwkcbl	330	28	Fisher	Fisher	NNP
cord-277648-9kxwkcbl	330	29	's	's	POS
cord-277648-9kxwkcbl	330	30	exact	exact	JJ
cord-277648-9kxwkcbl	330	31	test	test	NN
cord-277648-9kxwkcbl	330	32	,	,	,
cord-277648-9kxwkcbl	330	33	with	with	IN
cord-277648-9kxwkcbl	330	34	a	a	DT
cord-277648-9kxwkcbl	330	35	significance	significance	NN
cord-277648-9kxwkcbl	330	36	threshold	threshold	NN
cord-277648-9kxwkcbl	330	37	of	of	IN
cord-277648-9kxwkcbl	330	38	p<0.05	p<0.05	CD
cord-277648-9kxwkcbl	330	39	.	.	.
cord-277648-9kxwkcbl	331	1	ligand	ligand	NNP
cord-277648-9kxwkcbl	331	2	's	's	POS
cord-277648-9kxwkcbl	331	3	ability	ability	NN
cord-277648-9kxwkcbl	331	4	to	to	TO
cord-277648-9kxwkcbl	331	5	induce	induce	VB
cord-277648-9kxwkcbl	331	6	the	the	DT
cord-277648-9kxwkcbl	331	7	differential	differential	JJ
cord-277648-9kxwkcbl	331	8	gene	gene	NN
cord-277648-9kxwkcbl	331	9	expression	expression	NN
cord-277648-9kxwkcbl	331	10	measured	measure	VBN
cord-277648-9kxwkcbl	331	11	in	in	IN
cord-277648-9kxwkcbl	331	12	the	the	DT
cord-277648-9kxwkcbl	331	13	corresponding	correspond	VBG
cord-277648-9kxwkcbl	331	14	"	"	``
cord-277648-9kxwkcbl	331	15	receiver	receiver	NN
cord-277648-9kxwkcbl	331	16	"	"	''
cord-277648-9kxwkcbl	331	17	cell	cell	NN
cord-277648-9kxwkcbl	331	18	.	.	.
cord-277648-9kxwkcbl	332	1	A	a	DT
cord-277648-9kxwkcbl	332	2	new	new	JJ
cord-277648-9kxwkcbl	332	3	coronavirus	coronavirus	NN
cord-277648-9kxwkcbl	332	4	associated	associate	VBN
cord-277648-9kxwkcbl	332	5	with	with	IN
cord-277648-9kxwkcbl	332	6	human	human	JJ
cord-277648-9kxwkcbl	332	7	respiratory	respiratory	JJ
cord-277648-9kxwkcbl	332	8	disease	disease	NN
cord-277648-9kxwkcbl	332	9	in	in	IN
cord-277648-9kxwkcbl	332	10	China	China	NNP
cord-277648-9kxwkcbl	333	1	The	the	DT
cord-277648-9kxwkcbl	333	2	proximal	proximal	JJ
cord-277648-9kxwkcbl	333	3	origin	origin	NN
cord-277648-9kxwkcbl	333	4	of	of	IN
cord-277648-9kxwkcbl	333	5	SARS	SARS	NNP
cord-277648-9kxwkcbl	333	6	-	-	HYPH
cord-277648-9kxwkcbl	333	7	CoV-2	CoV-2	NNP
cord-277648-9kxwkcbl	334	1	Cross	Cross	NNP
cord-277648-9kxwkcbl	334	2	-	-	NNP
cord-277648-9kxwkcbl	334	3	Country	Country	NNP
cord-277648-9kxwkcbl	334	4	Comparison	Comparison	NNP
cord-277648-9kxwkcbl	334	5	of	of	IN
cord-277648-9kxwkcbl	334	6	Case	Case	NNP
cord-277648-9kxwkcbl	334	7	Fatality	Fatality	NNP
cord-277648-9kxwkcbl	334	8	Rates	Rates	NNPS
cord-277648-9kxwkcbl	334	9	of	of	IN
cord-277648-9kxwkcbl	334	10	COVID-19	COVID-19	NNP
cord-277648-9kxwkcbl	334	11	/	/	SYM
cord-277648-9kxwkcbl	334	12	SARS	SARS	NNP
cord-277648-9kxwkcbl	334	13	-	-	HYPH
cord-277648-9kxwkcbl	334	14	COV-2	COV-2	NNP
cord-277648-9kxwkcbl	334	15	.	.	.
cord-277648-9kxwkcbl	335	1	Osong	Osong	NNP
cord-277648-9kxwkcbl	335	2	Public	Public	NNP
cord-277648-9kxwkcbl	335	3	Health	Health	NNP
cord-277648-9kxwkcbl	335	4	and	and	CC
cord-277648-9kxwkcbl	335	5	Research	Research	NNP
cord-277648-9kxwkcbl	335	6	Perspectives	Perspectives	NNPS
cord-277648-9kxwkcbl	336	1	COVID-19	covid-19	VB
cord-277648-9kxwkcbl	337	1	:	:	:
cord-277648-9kxwkcbl	337	2	Specific	specific	JJ
cord-277648-9kxwkcbl	337	3	and	and	CC
cord-277648-9kxwkcbl	337	4	Non	non	JJ
cord-277648-9kxwkcbl	337	5	-	-	JJ
cord-277648-9kxwkcbl	337	6	Specific	specific	JJ
cord-277648-9kxwkcbl	337	7	Clinical	clinical	JJ
cord-277648-9kxwkcbl	337	8	Manifestations	manifestation	NNS
cord-277648-9kxwkcbl	337	9	and	and	CC
cord-277648-9kxwkcbl	337	10	Symptoms	symptom	NNS
cord-277648-9kxwkcbl	337	11	:	:	:
cord-277648-9kxwkcbl	337	12	The	the	DT
cord-277648-9kxwkcbl	337	13	Current	current	JJ
cord-277648-9kxwkcbl	337	14	State	State	NNP
cord-277648-9kxwkcbl	337	15	of	of	IN
cord-277648-9kxwkcbl	337	16	Knowledge	Knowledge	NNP
cord-277648-9kxwkcbl	337	17	Characteristics	Characteristics	NNPS
cord-277648-9kxwkcbl	337	18	of	of	IN
cord-277648-9kxwkcbl	337	19	and	and	CC
cord-277648-9kxwkcbl	337	20	Important	important	JJ
cord-277648-9kxwkcbl	337	21	Lessons	lesson	NNS
cord-277648-9kxwkcbl	337	22	From	from	IN
cord-277648-9kxwkcbl	337	23	the	the	DT
cord-277648-9kxwkcbl	337	24	Coronavirus	Coronavirus	NNP
cord-277648-9kxwkcbl	337	25	Disease	Disease	NNP
cord-277648-9kxwkcbl	337	26	2019	2019	CD
cord-277648-9kxwkcbl	337	27	(	(	-LRB-
cord-277648-9kxwkcbl	337	28	COVID-19	COVID-19	NNP
cord-277648-9kxwkcbl	337	29	)	)	-RRB-
cord-277648-9kxwkcbl	337	30	Outbreak	outbreak	NN
cord-277648-9kxwkcbl	337	31	in	in	IN
cord-277648-9kxwkcbl	337	32	China	China	NNP
cord-277648-9kxwkcbl	337	33	:	:	:
cord-277648-9kxwkcbl	337	34	Summary	Summary	NNP
cord-277648-9kxwkcbl	337	35	of	of	IN
cord-277648-9kxwkcbl	337	36	a	a	DT
cord-277648-9kxwkcbl	337	37	Report	Report	NNP
cord-277648-9kxwkcbl	337	38	of	of	IN
cord-277648-9kxwkcbl	337	39	72	72	CD
cord-277648-9kxwkcbl	337	40	314	314	CD
cord-277648-9kxwkcbl	337	41	Cases	case	NNS
cord-277648-9kxwkcbl	337	42	From	from	IN
cord-277648-9kxwkcbl	337	43	the	the	DT
cord-277648-9kxwkcbl	337	44	Chinese	Chinese	NNP
cord-277648-9kxwkcbl	337	45	Center	Center	NNP
cord-277648-9kxwkcbl	337	46	for	for	IN
cord-277648-9kxwkcbl	337	47	Disease	Disease	NNP
cord-277648-9kxwkcbl	337	48	Control	Control	NNP
cord-277648-9kxwkcbl	337	49	and	and	CC
cord-277648-9kxwkcbl	338	1	Prevention	prevention	NN
cord-277648-9kxwkcbl	338	2	A	a	DT
cord-277648-9kxwkcbl	338	3	familial	familial	JJ
cord-277648-9kxwkcbl	338	4	cluster	cluster	NN
cord-277648-9kxwkcbl	338	5	of	of	IN
cord-277648-9kxwkcbl	338	6	pneumonia	pneumonia	NN
cord-277648-9kxwkcbl	338	7	associated	associate	VBN
cord-277648-9kxwkcbl	338	8	with	with	IN
cord-277648-9kxwkcbl	338	9	the	the	DT
cord-277648-9kxwkcbl	338	10	2019	2019	CD
cord-277648-9kxwkcbl	338	11	novel	novel	NN
cord-277648-9kxwkcbl	338	12	coronavirus	coronavirus	NN
cord-277648-9kxwkcbl	338	13	indicating	indicate	VBG
cord-277648-9kxwkcbl	338	14	person	person	NN
cord-277648-9kxwkcbl	338	15	-	-	HYPH
cord-277648-9kxwkcbl	338	16	to	to	IN
cord-277648-9kxwkcbl	338	17	-	-	HYPH
cord-277648-9kxwkcbl	338	18	person	person	NN
cord-277648-9kxwkcbl	338	19	transmission	transmission	NN
cord-277648-9kxwkcbl	338	20	:	:	:
cord-277648-9kxwkcbl	338	21	a	a	DT
cord-277648-9kxwkcbl	338	22	study	study	NN
cord-277648-9kxwkcbl	338	23	of	of	IN
cord-277648-9kxwkcbl	338	24	a	a	DT
cord-277648-9kxwkcbl	338	25	family	family	NN
cord-277648-9kxwkcbl	338	26	cluster	cluster	NN
cord-277648-9kxwkcbl	338	27	Pathological	pathological	JJ
cord-277648-9kxwkcbl	338	28	findings	finding	NNS
cord-277648-9kxwkcbl	338	29	of	of	IN
cord-277648-9kxwkcbl	338	30	COVID-19	COVID-19	NNP
cord-277648-9kxwkcbl	338	31	associated	associate	VBN
cord-277648-9kxwkcbl	338	32	with	with	IN
cord-277648-9kxwkcbl	338	33	acute	acute	JJ
cord-277648-9kxwkcbl	338	34	respiratory	respiratory	JJ
cord-277648-9kxwkcbl	338	35	distress	distress	NN
cord-277648-9kxwkcbl	338	36	syndrome	syndrome	NN
cord-277648-9kxwkcbl	338	37	Planning	planning	NN
cord-277648-9kxwkcbl	338	38	and	and	CC
cord-277648-9kxwkcbl	338	39	provision	provision	NN
cord-277648-9kxwkcbl	338	40	of	of	IN
cord-277648-9kxwkcbl	338	41	ECMO	ECMO	NNP
cord-277648-9kxwkcbl	338	42	services	service	NNS
cord-277648-9kxwkcbl	338	43	for	for	IN
cord-277648-9kxwkcbl	338	44	severe	severe	JJ
cord-277648-9kxwkcbl	338	45	ARDS	ARDS	NNP
cord-277648-9kxwkcbl	338	46	during	during	IN
cord-277648-9kxwkcbl	338	47	the	the	DT
cord-277648-9kxwkcbl	338	48	COVID-19	covid-19	JJ
cord-277648-9kxwkcbl	338	49	pandemic	pandemic	NN
cord-277648-9kxwkcbl	338	50	and	and	CC
cord-277648-9kxwkcbl	338	51	other	other	JJ
cord-277648-9kxwkcbl	338	52	outbreaks	outbreak	NNS
cord-277648-9kxwkcbl	338	53	of	of	IN
cord-277648-9kxwkcbl	338	54	emerging	emerge	VBG
cord-277648-9kxwkcbl	338	55	infectious	infectious	JJ
cord-277648-9kxwkcbl	338	56	diseases	disease	NNS
cord-277648-9kxwkcbl	338	57	Cytokine	cytokine	NN
cord-277648-9kxwkcbl	338	58	profile	profile	NN
cord-277648-9kxwkcbl	338	59	in	in	IN
cord-277648-9kxwkcbl	338	60	plasma	plasma	NN
cord-277648-9kxwkcbl	338	61	of	of	IN
cord-277648-9kxwkcbl	338	62	severe	severe	JJ
cord-277648-9kxwkcbl	338	63	COVID-19	covid-19	NN
cord-277648-9kxwkcbl	338	64	does	do	VBZ
cord-277648-9kxwkcbl	338	65	not	not	RB
cord-277648-9kxwkcbl	338	66	differ	differ	VB
cord-277648-9kxwkcbl	338	67	from	from	IN
cord-277648-9kxwkcbl	338	68	ARDS	ARDS	NNP
cord-277648-9kxwkcbl	338	69	and	and	CC
cord-277648-9kxwkcbl	338	70	sepsis	sepsis	NN
cord-277648-9kxwkcbl	339	1	COVID-19	COVID-19	NNP
cord-277648-9kxwkcbl	339	2	pneumonia	pneumonia	NN
cord-277648-9kxwkcbl	339	3	:	:	:
cord-277648-9kxwkcbl	339	4	ARDS	ARDS	NNP
cord-277648-9kxwkcbl	339	5	or	or	CC
cord-277648-9kxwkcbl	339	6	not	not	RB
cord-277648-9kxwkcbl	339	7	?	?	.
cord-277648-9kxwkcbl	340	1	An	an	DT
cord-277648-9kxwkcbl	340	2	inflammatory	inflammatory	JJ
cord-277648-9kxwkcbl	340	3	cytokine	cytokine	NN
cord-277648-9kxwkcbl	340	4	signature	signature	NN
cord-277648-9kxwkcbl	340	5	helps	help	VBZ
cord-277648-9kxwkcbl	340	6	predict	predict	VB
cord-277648-9kxwkcbl	340	7	COVID-19	covid-19	JJ
cord-277648-9kxwkcbl	340	8	severity	severity	NN
cord-277648-9kxwkcbl	340	9	and	and	CC
cord-277648-9kxwkcbl	340	10	death	death	NN
cord-277648-9kxwkcbl	340	11	COVID-19	covid-19	NN
cord-277648-9kxwkcbl	340	12	:	:	:
cord-277648-9kxwkcbl	340	13	consider	consider	VB
cord-277648-9kxwkcbl	340	14	cytokine	cytokine	JJ
cord-277648-9kxwkcbl	340	15	storm	storm	NN
cord-277648-9kxwkcbl	340	16	syndromes	syndrome	NNS
cord-277648-9kxwkcbl	340	17	and	and	CC
cord-277648-9kxwkcbl	340	18	immunosuppression	immunosuppression	NN
cord-277648-9kxwkcbl	340	19	Imbalanced	Imbalanced	NNP
cord-277648-9kxwkcbl	340	20	Host	Host	NNP
cord-277648-9kxwkcbl	340	21	Response	Response	NNP
cord-277648-9kxwkcbl	340	22	to	to	IN
cord-277648-9kxwkcbl	340	23	SARS	SARS	NNP
cord-277648-9kxwkcbl	340	24	-	-	HYPH
cord-277648-9kxwkcbl	340	25	CoV-2	CoV-2	NNP
cord-277648-9kxwkcbl	341	1	Drives	drive	VBZ
cord-277648-9kxwkcbl	341	2	Development	Development	NNP
cord-277648-9kxwkcbl	341	3	of	of	IN
cord-277648-9kxwkcbl	341	4	COVID-19	COVID-19	NNP
cord-277648-9kxwkcbl	341	5	Aveolar	Aveolar	NNP
cord-277648-9kxwkcbl	341	6	Macrophage	Macrophage	NNP
cord-277648-9kxwkcbl	341	7	Activation	Activation	NNP
cord-277648-9kxwkcbl	341	8	and	and	CC
cord-277648-9kxwkcbl	341	9	Cytokine	Cytokine	NNP
cord-277648-9kxwkcbl	341	10	Storm	storm	NN
cord-277648-9kxwkcbl	341	11	in	in	IN
cord-277648-9kxwkcbl	341	12	the	the	DT
cord-277648-9kxwkcbl	341	13	Pathogenesis	Pathogenesis	NNP
cord-277648-9kxwkcbl	341	14	of	of	IN
cord-277648-9kxwkcbl	341	15	Severe	Severe	NNP
cord-277648-9kxwkcbl	341	16	COVID-19	COVID-19	NNP
cord-277648-9kxwkcbl	341	17	Pulmonary	pulmonary	JJ
cord-277648-9kxwkcbl	341	18	post	post	JJ
cord-277648-9kxwkcbl	341	19	-	-	JJ
cord-277648-9kxwkcbl	341	20	mortem	mortem	JJ
cord-277648-9kxwkcbl	341	21	findings	finding	NNS
cord-277648-9kxwkcbl	341	22	in	in	IN
cord-277648-9kxwkcbl	341	23	a	a	DT
cord-277648-9kxwkcbl	341	24	large	large	JJ
cord-277648-9kxwkcbl	341	25	series	series	NN
cord-277648-9kxwkcbl	341	26	of	of	IN
cord-277648-9kxwkcbl	341	27	COVID-19	covid-19	JJ
cord-277648-9kxwkcbl	341	28	cases	case	NNS
cord-277648-9kxwkcbl	341	29	from	from	IN
cord-277648-9kxwkcbl	341	30	Northern	Northern	NNP
cord-277648-9kxwkcbl	341	31	Italy	Italy	NNP
cord-277648-9kxwkcbl	341	32	.	.	.
cord-277648-9kxwkcbl	342	1	The	the	DT
cord-277648-9kxwkcbl	342	2	Lancet	Lancet	NNP
cord-277648-9kxwkcbl	342	3	Infections	Infections	NNPS
cord-277648-9kxwkcbl	342	4	Disease	Disease	NNP
cord-277648-9kxwkcbl	342	5	Postmortem	Postmortem	NNP
cord-277648-9kxwkcbl	342	6	Examination	Examination	NNP
cord-277648-9kxwkcbl	342	7	of	of	IN
cord-277648-9kxwkcbl	342	8	Patients	Patients	NNP
cord-277648-9kxwkcbl	342	9	With	with	IN
cord-277648-9kxwkcbl	342	10	COVID-19	COVID-19	NNP
cord-277648-9kxwkcbl	342	11	Clinical	clinical	JJ
cord-277648-9kxwkcbl	342	12	course	course	NN
cord-277648-9kxwkcbl	342	13	and	and	CC
cord-277648-9kxwkcbl	342	14	risk	risk	NN
cord-277648-9kxwkcbl	342	15	factors	factor	NNS
cord-277648-9kxwkcbl	342	16	for	for	IN
cord-277648-9kxwkcbl	342	17	mortality	mortality	NN
cord-277648-9kxwkcbl	342	18	of	of	IN
cord-277648-9kxwkcbl	342	19	adult	adult	NN
cord-277648-9kxwkcbl	342	20	inpatients	inpatient	NNS
cord-277648-9kxwkcbl	342	21	with	with	IN
cord-277648-9kxwkcbl	342	22	COVID-19	COVID-19	NNP
cord-277648-9kxwkcbl	342	23	in	in	IN
cord-277648-9kxwkcbl	342	24	Wuhan	Wuhan	NNP
cord-277648-9kxwkcbl	342	25	,	,	,
cord-277648-9kxwkcbl	342	26	China	China	NNP
cord-277648-9kxwkcbl	342	27	:	:	:
cord-277648-9kxwkcbl	343	1	a	a	DT
cord-277648-9kxwkcbl	343	2	retrospective	retrospective	JJ
cord-277648-9kxwkcbl	343	3	cohort	cohort	NN
cord-277648-9kxwkcbl	343	4	study	study	NN
cord-277648-9kxwkcbl	343	5	Baseline	Baseline	NNP
cord-277648-9kxwkcbl	343	6	Characteristics	Characteristics	NNP
cord-277648-9kxwkcbl	343	7	and	and	CC
cord-277648-9kxwkcbl	343	8	Outcomes	Outcomes	NNPS
cord-277648-9kxwkcbl	343	9	of	of	IN
cord-277648-9kxwkcbl	343	10	1591	1591	CD
cord-277648-9kxwkcbl	343	11	Patients	patient	NNS
cord-277648-9kxwkcbl	343	12	Infected	infect	VBN
cord-277648-9kxwkcbl	343	13	With	with	IN
cord-277648-9kxwkcbl	343	14	SARS	SARS	NNP
cord-277648-9kxwkcbl	343	15	-	-	HYPH
cord-277648-9kxwkcbl	343	16	CoV-2	CoV-2	NNP
cord-277648-9kxwkcbl	344	1	Admitted	admit	VBN
cord-277648-9kxwkcbl	344	2	to	to	IN
cord-277648-9kxwkcbl	344	3	ICUs	ICUs	NNP
cord-277648-9kxwkcbl	344	4	of	of	IN
cord-277648-9kxwkcbl	344	5	the	the	DT
cord-277648-9kxwkcbl	344	6	Lombardy	Lombardy	NNP
cord-277648-9kxwkcbl	344	7	Region	Region	NNP
cord-277648-9kxwkcbl	344	8	Characteristics	Characteristics	NNPS
cord-277648-9kxwkcbl	344	9	and	and	CC
cord-277648-9kxwkcbl	344	10	Outcomes	Outcomes	NNPS
cord-277648-9kxwkcbl	344	11	of	of	IN
cord-277648-9kxwkcbl	344	12	21	21	CD
cord-277648-9kxwkcbl	344	13	Critically	critically	RB
cord-277648-9kxwkcbl	344	14	Ill	Ill	NNP
cord-277648-9kxwkcbl	344	15	Patients	Patients	NNPS
cord-277648-9kxwkcbl	344	16	With	with	IN
cord-277648-9kxwkcbl	344	17	COVID-19	COVID-19	NNP
cord-277648-9kxwkcbl	344	18	in	in	IN
cord-277648-9kxwkcbl	344	19	Washington	Washington	NNP
cord-277648-9kxwkcbl	344	20	State	State	NNP
cord-277648-9kxwkcbl	344	21	Transcriptomic	Transcriptomic	NNP
cord-277648-9kxwkcbl	344	22	characteristics	characteristic	NNS
cord-277648-9kxwkcbl	344	23	of	of	IN
cord-277648-9kxwkcbl	344	24	bronchoalveolar	bronchoalveolar	NNP
cord-277648-9kxwkcbl	344	25	lavage	lavage	NN
cord-277648-9kxwkcbl	344	26	fluid	fluid	NN
cord-277648-9kxwkcbl	344	27	and	and	CC
cord-277648-9kxwkcbl	344	28	peripheral	peripheral	JJ
cord-277648-9kxwkcbl	344	29	blood	blood	NN
cord-277648-9kxwkcbl	344	30	mononuclear	mononuclear	NN
cord-277648-9kxwkcbl	344	31	cells	cell	NNS
cord-277648-9kxwkcbl	344	32	in	in	IN
cord-277648-9kxwkcbl	344	33	COVID-19	COVID-19	NNP
cord-277648-9kxwkcbl	344	34	patients	patient	NNS
cord-277648-9kxwkcbl	344	35	Comprehensive	Comprehensive	NNP
cord-277648-9kxwkcbl	344	36	Transcriptomic	Transcriptomic	NNP
cord-277648-9kxwkcbl	344	37	Analysis	Analysis	NNP
cord-277648-9kxwkcbl	344	38	of	of	IN
cord-277648-9kxwkcbl	344	39	COVID-19	COVID-19	NNP
cord-277648-9kxwkcbl	344	40	Blood	Blood	NNP
cord-277648-9kxwkcbl	344	41	,	,	,
cord-277648-9kxwkcbl	344	42	Lung	Lung	NNP
cord-277648-9kxwkcbl	344	43	,	,	,
cord-277648-9kxwkcbl	344	44	and	and	CC
cord-277648-9kxwkcbl	344	45	Airway	Airway	NNP
cord-277648-9kxwkcbl	344	46	Tocilizumab	Tocilizumab	NNP
cord-277648-9kxwkcbl	344	47	treatment	treatment	NN
cord-277648-9kxwkcbl	344	48	in	in	IN
cord-277648-9kxwkcbl	344	49	severe	severe	JJ
cord-277648-9kxwkcbl	344	50	COVID-19	covid-19	JJ
cord-277648-9kxwkcbl	344	51	patients	patient	NNS
cord-277648-9kxwkcbl	344	52	attenuates	attenuate	VBZ
cord-277648-9kxwkcbl	344	53	the	the	DT
cord-277648-9kxwkcbl	344	54	inflammatory	inflammatory	JJ
cord-277648-9kxwkcbl	344	55	storm	storm	NN
cord-277648-9kxwkcbl	344	56	incited	incite	VBN
cord-277648-9kxwkcbl	344	57	by	by	IN
cord-277648-9kxwkcbl	344	58	monocyte	monocyte	NNP
cord-277648-9kxwkcbl	344	59	centric	centric	NNP
cord-277648-9kxwkcbl	344	60	immune	immune	JJ
cord-277648-9kxwkcbl	344	61	interactions	interaction	NNS
cord-277648-9kxwkcbl	344	62	revealed	reveal	VBN
cord-277648-9kxwkcbl	344	63	by	by	IN
cord-277648-9kxwkcbl	344	64	single	single	JJ
cord-277648-9kxwkcbl	344	65	-	-	HYPH
cord-277648-9kxwkcbl	344	66	cell	cell	NN
cord-277648-9kxwkcbl	344	67	analysis	analysis	NN
cord-277648-9kxwkcbl	345	1	Blood	blood	NN
cord-277648-9kxwkcbl	345	2	single	single	JJ
cord-277648-9kxwkcbl	345	3	cell	cell	NN
cord-277648-9kxwkcbl	345	4	immune	immune	NN
cord-277648-9kxwkcbl	345	5	profiling	profiling	NN
cord-277648-9kxwkcbl	345	6	reveals	reveal	VBZ
cord-277648-9kxwkcbl	345	7	the	the	DT
cord-277648-9kxwkcbl	345	8	interferon	interferon	NN
cord-277648-9kxwkcbl	345	9	-	-	HYPH
cord-277648-9kxwkcbl	345	10	MAPK	MAPK	NNP
cord-277648-9kxwkcbl	345	11	pathway	pathway	NN
cord-277648-9kxwkcbl	345	12	mediated	mediate	VBD
cord-277648-9kxwkcbl	345	13	adaptive	adaptive	JJ
cord-277648-9kxwkcbl	345	14	immune	immune	JJ
cord-277648-9kxwkcbl	345	15	response	response	NN
cord-277648-9kxwkcbl	345	16	for	for	IN
cord-277648-9kxwkcbl	345	17	COVID-19	COVID-19	NNP
cord-277648-9kxwkcbl	345	18	Single	Single	NNP
cord-277648-9kxwkcbl	345	19	-	-	HYPH
cord-277648-9kxwkcbl	345	20	Cell	Cell	NNP
cord-277648-9kxwkcbl	345	21	Analysis	Analysis	NNP
cord-277648-9kxwkcbl	346	1	Reveals	reveal	VBZ
cord-277648-9kxwkcbl	346	2	Macrophage	macrophage	NN
cord-277648-9kxwkcbl	346	3	-	-	HYPH
cord-277648-9kxwkcbl	346	4	Driven	drive	VBN
cord-277648-9kxwkcbl	346	5	T	T	NNP
cord-277648-9kxwkcbl	346	6	Cell	cell	NN
cord-277648-9kxwkcbl	346	7	Dysfunction	dysfunction	NN
cord-277648-9kxwkcbl	346	8	in	in	IN
cord-277648-9kxwkcbl	346	9	Severe	severe	JJ
cord-277648-9kxwkcbl	346	10	COVID-19	COVID-19	NNP
cord-277648-9kxwkcbl	346	11	Patients	Patients	NNP
cord-277648-9kxwkcbl	346	12	Ellebedy	Ellebedy	NNP
cord-277648-9kxwkcbl	346	13	AH	ah	NN
cord-277648-9kxwkcbl	346	14	(	(	-LRB-
cord-277648-9kxwkcbl	346	15	2020	2020	CD
cord-277648-9kxwkcbl	346	16	)	)	-RRB-
cord-277648-9kxwkcbl	347	1	Targeted	target	VBN
cord-277648-9kxwkcbl	347	2	Immunosuppression	Immunosuppression	NNP
cord-277648-9kxwkcbl	347	3	Distinguishes	distinguish	VBZ
cord-277648-9kxwkcbl	347	4	COVID-19	COVID-19	NNP
cord-277648-9kxwkcbl	347	5	from	from	IN
cord-277648-9kxwkcbl	347	6	Influenza	Influenza	NNP
cord-277648-9kxwkcbl	347	7	in	in	IN
cord-277648-9kxwkcbl	347	8	Moderate	Moderate	NNP
cord-277648-9kxwkcbl	347	9	and	and	CC
cord-277648-9kxwkcbl	347	10	Severe	severe	JJ
cord-277648-9kxwkcbl	347	11	Disease	Disease	NNP
cord-277648-9kxwkcbl	347	12	Single	single	JJ
cord-277648-9kxwkcbl	347	13	-	-	HYPH
cord-277648-9kxwkcbl	347	14	cell	cell	NN
cord-277648-9kxwkcbl	347	15	landscape	landscape	NN
cord-277648-9kxwkcbl	347	16	of	of	IN
cord-277648-9kxwkcbl	347	17	bronchoalveolar	bronchoalveolar	JJ
cord-277648-9kxwkcbl	347	18	immune	immune	JJ
cord-277648-9kxwkcbl	347	19	cells	cell	NNS
cord-277648-9kxwkcbl	347	20	in	in	IN
cord-277648-9kxwkcbl	347	21	patients	patient	NNS
cord-277648-9kxwkcbl	347	22	with	with	IN
cord-277648-9kxwkcbl	347	23	COVID-19	COVID-19	NNP
cord-277648-9kxwkcbl	347	24	Cross	Cross	NNP
cord-277648-9kxwkcbl	347	25	-	-	HYPH
cord-277648-9kxwkcbl	347	26	talk	talk	NN
cord-277648-9kxwkcbl	347	27	between	between	IN
cord-277648-9kxwkcbl	347	28	the	the	DT
cord-277648-9kxwkcbl	347	29	airway	airway	NN
cord-277648-9kxwkcbl	347	30	epithelium	epithelium	NN
cord-277648-9kxwkcbl	347	31	and	and	CC
cord-277648-9kxwkcbl	347	32	activated	activate	VBN
cord-277648-9kxwkcbl	347	33	immune	immune	JJ
cord-277648-9kxwkcbl	347	34	cells	cell	NNS
cord-277648-9kxwkcbl	347	35	defines	define	VBZ
cord-277648-9kxwkcbl	347	36	severity	severity	NN
cord-277648-9kxwkcbl	347	37	in	in	IN
cord-277648-9kxwkcbl	347	38	COVID-19	COVID-19	NNP
cord-277648-9kxwkcbl	347	39	In	in	IN
cord-277648-9kxwkcbl	347	40	-	-	HYPH
cord-277648-9kxwkcbl	347	41	depth	depth	NN
cord-277648-9kxwkcbl	347	42	phenotyping	phenotyping	NN
cord-277648-9kxwkcbl	347	43	of	of	IN
cord-277648-9kxwkcbl	347	44	human	human	JJ
cord-277648-9kxwkcbl	347	45	peripheral	peripheral	JJ
cord-277648-9kxwkcbl	347	46	blood	blood	NN
cord-277648-9kxwkcbl	347	47	mononuclear	mononuclear	NN
cord-277648-9kxwkcbl	347	48	cells	cell	NNS
cord-277648-9kxwkcbl	347	49	in	in	IN
cord-277648-9kxwkcbl	347	50	convalescent	convalescent	JJ
cord-277648-9kxwkcbl	347	51	COVID-19	covid-19	CD
cord-277648-9kxwkcbl	347	52	patients	patient	NNS
cord-277648-9kxwkcbl	347	53	following	follow	VBG
cord-277648-9kxwkcbl	347	54	a	a	DT
cord-277648-9kxwkcbl	347	55	moderate	moderate	JJ
cord-277648-9kxwkcbl	347	56	versus	versus	IN
cord-277648-9kxwkcbl	347	57	severe	severe	JJ
cord-277648-9kxwkcbl	347	58	disease	disease	NN
cord-277648-9kxwkcbl	347	59	course	course	NN
cord-277648-9kxwkcbl	347	60	Complex	Complex	NNP
cord-277648-9kxwkcbl	347	61	Immune	Immune	NNP
cord-277648-9kxwkcbl	347	62	Dysregulation	Dysregulation	NNP
cord-277648-9kxwkcbl	347	63	in	in	IN
cord-277648-9kxwkcbl	347	64	COVID-19	COVID-19	NNP
cord-277648-9kxwkcbl	347	65	Patients	Patients	NNPS
cord-277648-9kxwkcbl	347	66	with	with	IN
cord-277648-9kxwkcbl	347	67	Severe	severe	JJ
cord-277648-9kxwkcbl	347	68	Respiratory	respiratory	JJ
cord-277648-9kxwkcbl	347	69	Failure	failure	NN
cord-277648-9kxwkcbl	348	1	A	a	DT
cord-277648-9kxwkcbl	348	2	single	single	JJ
cord-277648-9kxwkcbl	348	3	-	-	HYPH
cord-277648-9kxwkcbl	348	4	cell	cell	NN
cord-277648-9kxwkcbl	348	5	atlas	atlas	NN
cord-277648-9kxwkcbl	348	6	of	of	IN
cord-277648-9kxwkcbl	348	7	the	the	DT
cord-277648-9kxwkcbl	348	8	peripheral	peripheral	JJ
cord-277648-9kxwkcbl	348	9	immune	immune	JJ
cord-277648-9kxwkcbl	348	10	response	response	NN
cord-277648-9kxwkcbl	348	11	to	to	IN
cord-277648-9kxwkcbl	348	12	severe	severe	JJ
cord-277648-9kxwkcbl	348	13	COVID-19	COVID-19	NNP
cord-277648-9kxwkcbl	348	14	Terrier	Terrier	NNP
cord-277648-9kxwkcbl	348	15	B	B	NNP
cord-277648-9kxwkcbl	348	16	(	(	-LRB-
cord-277648-9kxwkcbl	348	17	2020	2020	CD
cord-277648-9kxwkcbl	348	18	)	)	-RRB-
cord-277648-9kxwkcbl	349	1	Impaired	impaired	JJ
cord-277648-9kxwkcbl	349	2	type	type	NN
cord-277648-9kxwkcbl	350	1	I	-PRON-	PRP
cord-277648-9kxwkcbl	350	2	interferon	interferon	VBD
cord-277648-9kxwkcbl	350	3	activity	activity	NN
cord-277648-9kxwkcbl	350	4	and	and	CC
cord-277648-9kxwkcbl	350	5	exacerbated	exacerbate	VBD
cord-277648-9kxwkcbl	350	6	inflammatory	inflammatory	JJ
cord-277648-9kxwkcbl	350	7	responses	response	NNS
cord-277648-9kxwkcbl	350	8	in	in	IN
cord-277648-9kxwkcbl	350	9	severe	severe	JJ
cord-277648-9kxwkcbl	350	10	Covid-19	covid-19	NN
cord-277648-9kxwkcbl	350	11	patients	patient	NNS
cord-277648-9kxwkcbl	350	12	Immunologic	immunologic	JJ
cord-277648-9kxwkcbl	350	13	perturbations	perturbation	NNS
cord-277648-9kxwkcbl	350	14	in	in	IN
cord-277648-9kxwkcbl	350	15	severe	severe	JJ
cord-277648-9kxwkcbl	350	16	COVID-19	covid-19	NN
cord-277648-9kxwkcbl	351	1	/SARS	/sars	LS
cord-277648-9kxwkcbl	351	2	-	-	:
cord-277648-9kxwkcbl	351	3	CoV-2	cov-2	NN
cord-277648-9kxwkcbl	351	4	infection	infection	NN
cord-277648-9kxwkcbl	351	5	Emergence	emergence	NN
cord-277648-9kxwkcbl	351	6	of	of	IN
cord-277648-9kxwkcbl	351	7	Low	low	JJ
cord-277648-9kxwkcbl	351	8	-	-	HYPH
cord-277648-9kxwkcbl	351	9	density	density	NN
cord-277648-9kxwkcbl	351	10	Inflammatory	Inflammatory	NNP
cord-277648-9kxwkcbl	351	11	Neutrophils	Neutrophils	NNP
cord-277648-9kxwkcbl	351	12	Correlates	correlate	VBZ
cord-277648-9kxwkcbl	351	13	with	with	IN
cord-277648-9kxwkcbl	351	14	Hypercoagulable	Hypercoagulable	NNP
cord-277648-9kxwkcbl	351	15	State	State	NNP
cord-277648-9kxwkcbl	351	16	and	and	CC
cord-277648-9kxwkcbl	351	17	Disease	Disease	NNP
cord-277648-9kxwkcbl	351	18	Severity	Severity	NNP
cord-277648-9kxwkcbl	351	19	in	in	IN
cord-277648-9kxwkcbl	351	20	COVID-19	COVID-19	NNP
cord-277648-9kxwkcbl	351	21	Patients	Patients	NNP
cord-277648-9kxwkcbl	351	22	NicheNet	NicheNet	NNP
cord-277648-9kxwkcbl	351	23	:	:	:
cord-277648-9kxwkcbl	351	24	modeling	model	VBG
cord-277648-9kxwkcbl	351	25	intercellular	intercellular	JJ
cord-277648-9kxwkcbl	351	26	communication	communication	NN
cord-277648-9kxwkcbl	351	27	by	by	IN
cord-277648-9kxwkcbl	351	28	linking	link	VBG
cord-277648-9kxwkcbl	351	29	ligands	ligand	NNS
cord-277648-9kxwkcbl	351	30	to	to	TO
cord-277648-9kxwkcbl	351	31	target	target	VB
cord-277648-9kxwkcbl	351	32	genes	gene	NNS
cord-277648-9kxwkcbl	352	1	A	a	DT
cord-277648-9kxwkcbl	352	2	mass	mass	JJ
cord-277648-9kxwkcbl	352	3	spectrometric	spectrometric	NN
cord-277648-9kxwkcbl	352	4	-	-	HYPH
cord-277648-9kxwkcbl	352	5	derived	derive	VBN
cord-277648-9kxwkcbl	352	6	cell	cell	NN
cord-277648-9kxwkcbl	352	7	surface	surface	NN
cord-277648-9kxwkcbl	352	8	protein	protein	NN
cord-277648-9kxwkcbl	352	9	atlas	atlas	NNP
cord-277648-9kxwkcbl	352	10	Immune	Immune	NNP
cord-277648-9kxwkcbl	352	11	Cell	Cell	NNP
cord-277648-9kxwkcbl	352	12	Atlas	Atlas	NNP
cord-277648-9kxwkcbl	352	13	Single	single	JJ
cord-277648-9kxwkcbl	352	14	-	-	HYPH
cord-277648-9kxwkcbl	352	15	cell	cell	NN
cord-277648-9kxwkcbl	352	16	RNA	RNA	NNP
cord-277648-9kxwkcbl	352	17	-	-	HYPH
cord-277648-9kxwkcbl	352	18	seq	seq	NNP
cord-277648-9kxwkcbl	352	19	reveals	reveal	VBZ
cord-277648-9kxwkcbl	352	20	new	new	JJ
cord-277648-9kxwkcbl	352	21	types	type	NNS
cord-277648-9kxwkcbl	352	22	of	of	IN
cord-277648-9kxwkcbl	352	23	human	human	JJ
cord-277648-9kxwkcbl	352	24	blood	blood	NN
cord-277648-9kxwkcbl	352	25	dendritic	dendritic	JJ
cord-277648-9kxwkcbl	352	26	cells	cell	NNS
cord-277648-9kxwkcbl	352	27	,	,	,
cord-277648-9kxwkcbl	352	28	monocytes	monocyte	NNS
cord-277648-9kxwkcbl	352	29	,	,	,
cord-277648-9kxwkcbl	352	30	and	and	CC
cord-277648-9kxwkcbl	352	31	progenitors	progenitor	NNS
cord-277648-9kxwkcbl	352	32	H9N2	H9N2	NNP
cord-277648-9kxwkcbl	352	33	avian	avian	JJ
cord-277648-9kxwkcbl	352	34	influenza	influenza	NN
cord-277648-9kxwkcbl	352	35	infection	infection	NN
cord-277648-9kxwkcbl	352	36	altered	alter	VBD
cord-277648-9kxwkcbl	352	37	expression	expression	NN
cord-277648-9kxwkcbl	352	38	pattern	pattern	NN
cord-277648-9kxwkcbl	352	39	of	of	IN
cord-277648-9kxwkcbl	352	40	sphiogosine-1-phosphate	sphiogosine-1-phosphate	JJ
cord-277648-9kxwkcbl	352	41	receptor	receptor	NN
cord-277648-9kxwkcbl	352	42	1	1	CD
cord-277648-9kxwkcbl	352	43	in	in	IN
cord-277648-9kxwkcbl	352	44	BALB	BALB	NNP
cord-277648-9kxwkcbl	352	45	/	/	SYM
cord-277648-9kxwkcbl	352	46	c	c	NN
cord-277648-9kxwkcbl	352	47	mice	mouse	NNS
cord-277648-9kxwkcbl	353	1	The	the	DT
cord-277648-9kxwkcbl	353	2	alliance	alliance	NN
cord-277648-9kxwkcbl	353	3	of	of	IN
cord-277648-9kxwkcbl	353	4	sphingosine-1-phosphate	sphingosine-1-phosphate	NNP
cord-277648-9kxwkcbl	353	5	and	and	CC
cord-277648-9kxwkcbl	353	6	its	-PRON-	PRP$
cord-277648-9kxwkcbl	353	7	receptors	receptor	NNS
cord-277648-9kxwkcbl	353	8	in	in	IN
cord-277648-9kxwkcbl	353	9	immunity	immunity	NN
cord-277648-9kxwkcbl	353	10	Osteopontin	Osteopontin	NNP
cord-277648-9kxwkcbl	353	11	Modulates	modulate	VBZ
cord-277648-9kxwkcbl	354	1	the	the	DT
cord-277648-9kxwkcbl	354	2	Generation	Generation	NNP
cord-277648-9kxwkcbl	354	3	of	of	IN
cord-277648-9kxwkcbl	354	4	Memory	Memory	NNP
cord-277648-9kxwkcbl	354	5	CD8	CD8	NNP
cord-277648-9kxwkcbl	354	6	+	+	CC
cord-277648-9kxwkcbl	354	7	T	T	NNP
cord-277648-9kxwkcbl	354	8	Cells	cell	NNS
cord-277648-9kxwkcbl	354	9	during	during	IN
cord-277648-9kxwkcbl	354	10	Influenza	Influenza	NNP
cord-277648-9kxwkcbl	354	11	Virus	Virus	NNP
cord-277648-9kxwkcbl	354	12	Infection	Infection	NNP
cord-277648-9kxwkcbl	354	13	Deep	Deep	NNP
cord-277648-9kxwkcbl	354	14	immune	immune	JJ
cord-277648-9kxwkcbl	354	15	profiling	profiling	NN
cord-277648-9kxwkcbl	354	16	of	of	IN
cord-277648-9kxwkcbl	354	17	COVID-19	covid-19	JJ
cord-277648-9kxwkcbl	354	18	patients	patient	NNS
cord-277648-9kxwkcbl	354	19	reveals	reveal	VBZ
cord-277648-9kxwkcbl	354	20	patient	patient	JJ
cord-277648-9kxwkcbl	354	21	heterogeneity	heterogeneity	NN
cord-277648-9kxwkcbl	354	22	and	and	CC
cord-277648-9kxwkcbl	354	23	distinct	distinct	JJ
cord-277648-9kxwkcbl	354	24	immunotypes	immunotype	NNS
cord-277648-9kxwkcbl	354	25	with	with	IN
cord-277648-9kxwkcbl	354	26	implications	implication	NNS
cord-277648-9kxwkcbl	354	27	for	for	IN
cord-277648-9kxwkcbl	354	28	therapeutic	therapeutic	JJ
cord-277648-9kxwkcbl	354	29	interventions	intervention	NNS
cord-277648-9kxwkcbl	354	30	Emerging	Emerging	NNP
cord-277648-9kxwkcbl	354	31	functions	function	NNS
cord-277648-9kxwkcbl	354	32	of	of	IN
cord-277648-9kxwkcbl	354	33	amphiregulin	amphiregulin	NN
cord-277648-9kxwkcbl	354	34	in	in	IN
cord-277648-9kxwkcbl	354	35	orchestrating	orchestrate	VBG
cord-277648-9kxwkcbl	354	36	immunity	immunity	NN
cord-277648-9kxwkcbl	354	37	,	,	,
cord-277648-9kxwkcbl	354	38	inflammation	inflammation	NN
cord-277648-9kxwkcbl	354	39	,	,	,
cord-277648-9kxwkcbl	354	40	and	and	CC
cord-277648-9kxwkcbl	354	41	tissue	tissue	NN
cord-277648-9kxwkcbl	354	42	repair	repair	NN
cord-277648-9kxwkcbl	355	1	New	new	JJ
cord-277648-9kxwkcbl	355	2	fronts	front	NNS
cord-277648-9kxwkcbl	355	3	emerge	emerge	VBP
cord-277648-9kxwkcbl	355	4	in	in	IN
cord-277648-9kxwkcbl	355	5	the	the	DT
cord-277648-9kxwkcbl	355	6	influenza	influenza	NN
cord-277648-9kxwkcbl	355	7	cytokine	cytokine	NN
cord-277648-9kxwkcbl	355	8	storm	storm	NN
cord-277648-9kxwkcbl	356	1	IL-33	IL-33	NNP
cord-277648-9kxwkcbl	356	2	promotes	promote	VBZ
cord-277648-9kxwkcbl	356	3	an	an	DT
cord-277648-9kxwkcbl	356	4	innate	innate	JJ
cord-277648-9kxwkcbl	356	5	immune	immune	JJ
cord-277648-9kxwkcbl	356	6	pathway	pathway	NN
cord-277648-9kxwkcbl	356	7	of	of	IN
cord-277648-9kxwkcbl	356	8	intestinal	intestinal	JJ
cord-277648-9kxwkcbl	356	9	tissue	tissue	NN
cord-277648-9kxwkcbl	356	10	protection	protection	NN
cord-277648-9kxwkcbl	356	11	dependent	dependent	JJ
cord-277648-9kxwkcbl	356	12	on	on	IN
cord-277648-9kxwkcbl	356	13	amphiregulin	amphiregulin	JJ
cord-277648-9kxwkcbl	356	14	-	-	HYPH
cord-277648-9kxwkcbl	356	15	EGFR	egfr	NN
cord-277648-9kxwkcbl	356	16	interactions	interaction	NNS
cord-277648-9kxwkcbl	356	17	TIMP-1	TIMP-1	NNP
cord-277648-9kxwkcbl	356	18	Promotes	promote	VBZ
cord-277648-9kxwkcbl	356	19	the	the	DT
cord-277648-9kxwkcbl	356	20	Immune	Immune	NNP
cord-277648-9kxwkcbl	356	21	Response	response	NN
cord-277648-9kxwkcbl	356	22	in	in	IN
cord-277648-9kxwkcbl	356	23	Influenza	Influenza	NNP
cord-277648-9kxwkcbl	356	24	-	-	HYPH
cord-277648-9kxwkcbl	356	25	Induced	Induced	NNP
cord-277648-9kxwkcbl	356	26	Acute	Acute	NNP
cord-277648-9kxwkcbl	356	27	Lung	Lung	NNP
cord-277648-9kxwkcbl	356	28	Injury	Injury	NNP
cord-277648-9kxwkcbl	356	29	Integrative	Integrative	NNP
cord-277648-9kxwkcbl	356	30	gene	gene	NN
cord-277648-9kxwkcbl	356	31	network	network	NN
cord-277648-9kxwkcbl	356	32	analysis	analysis	NN
cord-277648-9kxwkcbl	357	1	identifies	identify	VBZ
cord-277648-9kxwkcbl	357	2	key	key	JJ
cord-277648-9kxwkcbl	357	3	signatures	signature	NNS
cord-277648-9kxwkcbl	357	4	,	,	,
cord-277648-9kxwkcbl	357	5	intrinsic	intrinsic	JJ
cord-277648-9kxwkcbl	357	6	networks	network	NNS
cord-277648-9kxwkcbl	357	7	and	and	CC
cord-277648-9kxwkcbl	357	8	host	host	NN
cord-277648-9kxwkcbl	357	9	factors	factor	NNS
cord-277648-9kxwkcbl	357	10	for	for	IN
cord-277648-9kxwkcbl	357	11	influenza	influenza	NN
cord-277648-9kxwkcbl	357	12	virus	virus	NN
cord-277648-9kxwkcbl	358	1	A	a	DT
cord-277648-9kxwkcbl	358	2	infections	infection	NNS
cord-277648-9kxwkcbl	359	1	Patient	patient	NN
cord-277648-9kxwkcbl	359	2	-	-	HYPH
cord-277648-9kxwkcbl	359	3	based	base	VBN
cord-277648-9kxwkcbl	359	4	transcriptome	transcriptome	NN
cord-277648-9kxwkcbl	359	5	-	-	HYPH
cord-277648-9kxwkcbl	359	6	wide	wide	JJ
cord-277648-9kxwkcbl	359	7	analysis	analysis	NN
cord-277648-9kxwkcbl	359	8	identify	identify	VBP
cord-277648-9kxwkcbl	359	9	interferon	interferon	NN
cord-277648-9kxwkcbl	359	10	and	and	CC
cord-277648-9kxwkcbl	359	11	ubiquination	ubiquination	NN
cord-277648-9kxwkcbl	359	12	pathways	pathway	NNS
cord-277648-9kxwkcbl	359	13	as	as	IN
cord-277648-9kxwkcbl	359	14	potential	potential	JJ
cord-277648-9kxwkcbl	359	15	predictors	predictor	NNS
cord-277648-9kxwkcbl	359	16	of	of	IN
cord-277648-9kxwkcbl	359	17	influenza	influenza	NN
cord-277648-9kxwkcbl	359	18	A	a	DT
cord-277648-9kxwkcbl	359	19	disease	disease	NN
cord-277648-9kxwkcbl	359	20	severity	severity	NN
cord-277648-9kxwkcbl	359	21	Interleukin-7	interleukin-7	IN
cord-277648-9kxwkcbl	359	22	expression	expression	NN
cord-277648-9kxwkcbl	359	23	and	and	CC
cord-277648-9kxwkcbl	359	24	its	-PRON-	PRP$
cord-277648-9kxwkcbl	359	25	effect	effect	NN
cord-277648-9kxwkcbl	359	26	on	on	IN
cord-277648-9kxwkcbl	359	27	natural	natural	JJ
cord-277648-9kxwkcbl	359	28	killer	killer	NN
cord-277648-9kxwkcbl	359	29	cells	cell	NNS
cord-277648-9kxwkcbl	359	30	in	in	IN
cord-277648-9kxwkcbl	359	31	patients	patient	NNS
cord-277648-9kxwkcbl	359	32	with	with	IN
cord-277648-9kxwkcbl	359	33	multiple	multiple	JJ
cord-277648-9kxwkcbl	359	34	sclerosis	sclerosis	NN
cord-277648-9kxwkcbl	359	35	Endothelial	endothelial	NN
cord-277648-9kxwkcbl	359	36	cells	cell	NNS
cord-277648-9kxwkcbl	359	37	are	be	VBP
cord-277648-9kxwkcbl	359	38	central	central	JJ
cord-277648-9kxwkcbl	359	39	orchestrators	orchestrator	NNS
cord-277648-9kxwkcbl	359	40	of	of	IN
cord-277648-9kxwkcbl	359	41	cytokine	cytokine	NN
cord-277648-9kxwkcbl	359	42	amplification	amplification	NN
cord-277648-9kxwkcbl	359	43	during	during	IN
cord-277648-9kxwkcbl	360	1	influenza	influenza	NN
cord-277648-9kxwkcbl	360	2	virus	virus	NN
cord-277648-9kxwkcbl	360	3	infection	infection	NN
cord-277648-9kxwkcbl	360	4	SARS	SARS	NNP
cord-277648-9kxwkcbl	360	5	-	-	HYPH
cord-277648-9kxwkcbl	360	6	CoV-2	CoV-2	NNP
cord-277648-9kxwkcbl	360	7	activates	activate	VBZ
cord-277648-9kxwkcbl	360	8	lung	lung	NN
cord-277648-9kxwkcbl	360	9	epithelia	epithelia	NN
cord-277648-9kxwkcbl	360	10	cell	cell	NN
cord-277648-9kxwkcbl	360	11	proinflammatory	proinflammatory	JJ
cord-277648-9kxwkcbl	360	12	signaling	signaling	NN
cord-277648-9kxwkcbl	360	13	and	and	CC
cord-277648-9kxwkcbl	360	14	leads	lead	VBZ
cord-277648-9kxwkcbl	360	15	to	to	IN
cord-277648-9kxwkcbl	360	16	immune	immune	JJ
cord-277648-9kxwkcbl	360	17	dysregulation	dysregulation	NN
cord-277648-9kxwkcbl	360	18	in	in	IN
cord-277648-9kxwkcbl	360	19	COVID-19	covid-19	JJ
cord-277648-9kxwkcbl	360	20	patients	patient	NNS
cord-277648-9kxwkcbl	360	21	by	by	IN
cord-277648-9kxwkcbl	360	22	single	single	JJ
cord-277648-9kxwkcbl	360	23	-	-	HYPH
cord-277648-9kxwkcbl	360	24	cell	cell	NN
cord-277648-9kxwkcbl	360	25	sequencing	sequencing	NN
cord-277648-9kxwkcbl	360	26	Immune	immune	JJ
cord-277648-9kxwkcbl	360	27	cell	cell	NN
cord-277648-9kxwkcbl	360	28	profiling	profiling	NN
cord-277648-9kxwkcbl	360	29	of	of	IN
cord-277648-9kxwkcbl	360	30	COVID-19	covid-19	JJ
cord-277648-9kxwkcbl	360	31	patients	patient	NNS
cord-277648-9kxwkcbl	360	32	in	in	IN
cord-277648-9kxwkcbl	360	33	the	the	DT
cord-277648-9kxwkcbl	360	34	recovery	recovery	NN
cord-277648-9kxwkcbl	360	35	stage	stage	NN
cord-277648-9kxwkcbl	360	36	by	by	IN
cord-277648-9kxwkcbl	360	37	singlecell	singlecell	NNP
cord-277648-9kxwkcbl	360	38	sequencing	sequence	VBG
cord-277648-9kxwkcbl	360	39	Longitudinal	longitudinal	JJ
cord-277648-9kxwkcbl	360	40	peripheral	peripheral	JJ
cord-277648-9kxwkcbl	360	41	blood	blood	NN
cord-277648-9kxwkcbl	360	42	transcriptional	transcriptional	JJ
cord-277648-9kxwkcbl	360	43	analysis	analysis	NN
cord-277648-9kxwkcbl	360	44	of	of	IN
cord-277648-9kxwkcbl	360	45	COVID-19	COVID-19	NNP
cord-277648-9kxwkcbl	360	46	patients	patient	NNS
cord-277648-9kxwkcbl	360	47	captures	capture	VBZ
cord-277648-9kxwkcbl	360	48	disease	disease	NN
cord-277648-9kxwkcbl	360	49	progression	progression	NN
cord-277648-9kxwkcbl	360	50	and	and	CC
cord-277648-9kxwkcbl	360	51	reveals	reveal	VBZ
cord-277648-9kxwkcbl	360	52	potential	potential	JJ
cord-277648-9kxwkcbl	360	53	biomarkers	biomarker	NNS
cord-277648-9kxwkcbl	360	54	The	the	DT
cord-277648-9kxwkcbl	360	55	tumor	tumor	NN
cord-277648-9kxwkcbl	360	56	necrosis	necrosis	NN
cord-277648-9kxwkcbl	360	57	factor	factor	NN
cord-277648-9kxwkcbl	360	58	alpha	alpha	NN
cord-277648-9kxwkcbl	360	59	-	-	HYPH
cord-277648-9kxwkcbl	360	60	induced	induce	VBN
cord-277648-9kxwkcbl	360	61	protein	protein	NN
cord-277648-9kxwkcbl	360	62	3	3	CD
cord-277648-9kxwkcbl	360	63	(	(	-LRB-
cord-277648-9kxwkcbl	360	64	TNFAIP3	TNFAIP3	NNP
cord-277648-9kxwkcbl	360	65	,	,	,
cord-277648-9kxwkcbl	360	66	A20	A20	NNP
cord-277648-9kxwkcbl	360	67	)	)	-RRB-
cord-277648-9kxwkcbl	360	68	imposes	impose	VBZ
cord-277648-9kxwkcbl	360	69	a	a	DT
cord-277648-9kxwkcbl	360	70	brake	brake	NN
cord-277648-9kxwkcbl	360	71	on	on	IN
cord-277648-9kxwkcbl	360	72	antitumor	antitumor	JJ
cord-277648-9kxwkcbl	360	73	activity	activity	NN
cord-277648-9kxwkcbl	360	74	of	of	IN
cord-277648-9kxwkcbl	360	75	CD8	CD8	NNP
cord-277648-9kxwkcbl	360	76	T	T	NNP
cord-277648-9kxwkcbl	360	77	cells	cell	NNS
cord-277648-9kxwkcbl	361	1	A20	A20	NNP
cord-277648-9kxwkcbl	361	2	/	/	SYM
cord-277648-9kxwkcbl	361	3	Tumor	tumor	NN
cord-277648-9kxwkcbl	361	4	Necrosis	necrosis	NN
cord-277648-9kxwkcbl	361	5	Factor	Factor	NNP
cord-277648-9kxwkcbl	361	6	α	α	NN
cord-277648-9kxwkcbl	361	7	-	-	HYPH
cord-277648-9kxwkcbl	361	8	Induced	induce	VBN
cord-277648-9kxwkcbl	361	9	Protein	Protein	NNP
cord-277648-9kxwkcbl	361	10	3	3	CD
cord-277648-9kxwkcbl	361	11	in	in	IN
cord-277648-9kxwkcbl	361	12	Immune	Immune	NNP
cord-277648-9kxwkcbl	361	13	Cells	Cells	NNPS
cord-277648-9kxwkcbl	361	14	Controls	control	VBZ
cord-277648-9kxwkcbl	361	15	Development	Development	NNP
cord-277648-9kxwkcbl	361	16	of	of	IN
cord-277648-9kxwkcbl	361	17	Autoinflammation	Autoinflammation	NNP
cord-277648-9kxwkcbl	361	18	and	and	CC
cord-277648-9kxwkcbl	361	19	Autoimmunity	Autoimmunity	NNP
cord-277648-9kxwkcbl	361	20	:	:	:
cord-277648-9kxwkcbl	361	21	Lessons	lesson	NNS
cord-277648-9kxwkcbl	361	22	from	from	IN
cord-277648-9kxwkcbl	361	23	Mouse	Mouse	NNP
cord-277648-9kxwkcbl	361	24	Models	Models	NNPS
cord-277648-9kxwkcbl	361	25	.	.	.
cord-277648-9kxwkcbl	362	1	Front	Front	NNP
cord-277648-9kxwkcbl	362	2	Immunol	Immunol	NNP
cord-277648-9kxwkcbl	362	3	A20	A20	NNP
cord-277648-9kxwkcbl	362	4	and	and	CC
cord-277648-9kxwkcbl	362	5	Cell	Cell	NNP
cord-277648-9kxwkcbl	362	6	Death	death	NN
cord-277648-9kxwkcbl	362	7	-	-	HYPH
cord-277648-9kxwkcbl	362	8	driven	drive	VBN
cord-277648-9kxwkcbl	362	9	Inflammation	inflammation	NN
cord-277648-9kxwkcbl	362	10	A20	A20	NNP
cord-277648-9kxwkcbl	362	11	Deficiency	deficiency	NN
cord-277648-9kxwkcbl	362	12	in	in	IN
cord-277648-9kxwkcbl	362	13	Lung	Lung	NNP
cord-277648-9kxwkcbl	362	14	Epithelial	epithelial	NN
cord-277648-9kxwkcbl	362	15	Cells	Cells	NNPS
cord-277648-9kxwkcbl	362	16	Protects	protect	VBZ
cord-277648-9kxwkcbl	362	17	against	against	IN
cord-277648-9kxwkcbl	362	18	Influenza	Influenza	NNP
cord-277648-9kxwkcbl	362	19	A	A	NNP
cord-277648-9kxwkcbl	362	20	Virus	Virus	NNP
cord-277648-9kxwkcbl	362	21	Infection	Infection	NNP
cord-277648-9kxwkcbl	362	22	Network	network	NN
cord-277648-9kxwkcbl	362	23	-	-	HYPH
cord-277648-9kxwkcbl	362	24	based	base	VBN
cord-277648-9kxwkcbl	362	25	analysis	analysis	NN
cord-277648-9kxwkcbl	362	26	of	of	IN
cord-277648-9kxwkcbl	362	27	comorbidities	comorbiditie	NNS
cord-277648-9kxwkcbl	362	28	risk	risk	NN
cord-277648-9kxwkcbl	362	29	during	during	IN
cord-277648-9kxwkcbl	362	30	an	an	DT
cord-277648-9kxwkcbl	362	31	infection	infection	NN
cord-277648-9kxwkcbl	362	32	:	:	:
cord-277648-9kxwkcbl	362	33	SARS	SARS	NNP
cord-277648-9kxwkcbl	362	34	and	and	CC
cord-277648-9kxwkcbl	362	35	HIV	HIV	NNP
cord-277648-9kxwkcbl	362	36	case	case	NN
cord-277648-9kxwkcbl	362	37	studies	study	VBZ
cord-277648-9kxwkcbl	362	38	Neutrophils	Neutrophils	NNP
cord-277648-9kxwkcbl	362	39	in	in	IN
cord-277648-9kxwkcbl	362	40	cystic	cystic	JJ
cord-277648-9kxwkcbl	362	41	fibrosis	fibrosis	NN
cord-277648-9kxwkcbl	362	42	display	display	VBP
cord-277648-9kxwkcbl	362	43	a	a	DT
cord-277648-9kxwkcbl	362	44	distinct	distinct	JJ
cord-277648-9kxwkcbl	362	45	gene	gene	NN
cord-277648-9kxwkcbl	362	46	expression	expression	NN
cord-277648-9kxwkcbl	362	47	pattern	pattern	NN
cord-277648-9kxwkcbl	363	1	The	the	DT
cord-277648-9kxwkcbl	363	2	Role	role	NN
cord-277648-9kxwkcbl	363	3	of	of	IN
cord-277648-9kxwkcbl	363	4	Cytokines	Cytokines	NNPS
cord-277648-9kxwkcbl	363	5	including	include	VBG
cord-277648-9kxwkcbl	363	6	Interleukin-6	Interleukin-6	NNP
cord-277648-9kxwkcbl	363	7	in	in	IN
cord-277648-9kxwkcbl	363	8	COVID-19	COVID-19	NNP
cord-277648-9kxwkcbl	363	9	induced	induce	VBN
cord-277648-9kxwkcbl	363	10	Pneumonia	Pneumonia	NNP
cord-277648-9kxwkcbl	363	11	and	and	CC
cord-277648-9kxwkcbl	363	12	Macrophage	Macrophage	NNP
cord-277648-9kxwkcbl	363	13	Activation	Activation	NNP
cord-277648-9kxwkcbl	363	14	Syndrome	Syndrome	NNP
cord-277648-9kxwkcbl	364	1	-Like	-Like	NNP
cord-277648-9kxwkcbl	364	2	Disease	Disease	NNP
cord-277648-9kxwkcbl	365	1	Should	Should	MD
cord-277648-9kxwkcbl	365	2	we	-PRON-	PRP
cord-277648-9kxwkcbl	365	3	stimulate	stimulate	VB
cord-277648-9kxwkcbl	365	4	or	or	CC
cord-277648-9kxwkcbl	365	5	suppress	suppress	VB
cord-277648-9kxwkcbl	365	6	immune	immune	JJ
cord-277648-9kxwkcbl	365	7	responses	response	NNS
cord-277648-9kxwkcbl	365	8	in	in	IN
cord-277648-9kxwkcbl	365	9	COVID-19	COVID-19	NNP
cord-277648-9kxwkcbl	365	10	?	?	.
cord-277648-9kxwkcbl	366	1	Cytokine	cytokine	NN
cord-277648-9kxwkcbl	366	2	and	and	CC
cord-277648-9kxwkcbl	366	3	anti	anti	JJ
cord-277648-9kxwkcbl	366	4	-	-	JJ
cord-277648-9kxwkcbl	366	5	cytokine	cytokine	JJ
cord-277648-9kxwkcbl	366	6	interventions	intervention	NNS
cord-277648-9kxwkcbl	367	1	Proliferating	proliferate	VBG
cord-277648-9kxwkcbl	368	1	SPP1	SPP1	NNP
cord-277648-9kxwkcbl	368	2	/	/	SYM
cord-277648-9kxwkcbl	368	3	MERTK	mertk	NN
cord-277648-9kxwkcbl	368	4	-	-	HYPH
cord-277648-9kxwkcbl	368	5	expressing	express	VBG
cord-277648-9kxwkcbl	368	6	macrophages	macrophage	NNS
cord-277648-9kxwkcbl	368	7	in	in	IN
cord-277648-9kxwkcbl	368	8	idiopathic	idiopathic	JJ
cord-277648-9kxwkcbl	368	9	pulmonary	pulmonary	JJ
cord-277648-9kxwkcbl	368	10	fibrosis	fibrosis	NN
cord-277648-9kxwkcbl	368	11	MAST	MAST	NNP
cord-277648-9kxwkcbl	368	12	:	:	:
cord-277648-9kxwkcbl	368	13	a	a	DT
cord-277648-9kxwkcbl	368	14	flexible	flexible	JJ
cord-277648-9kxwkcbl	368	15	statistical	statistical	JJ
cord-277648-9kxwkcbl	368	16	framework	framework	NN
cord-277648-9kxwkcbl	368	17	for	for	IN
cord-277648-9kxwkcbl	368	18	assessing	assess	VBG
cord-277648-9kxwkcbl	368	19	transcriptional	transcriptional	JJ
cord-277648-9kxwkcbl	368	20	changes	change	NNS
cord-277648-9kxwkcbl	368	21	and	and	CC
cord-277648-9kxwkcbl	368	22	characterizing	characterize	VBG
cord-277648-9kxwkcbl	368	23	heterogeneity	heterogeneity	NN
cord-277648-9kxwkcbl	368	24	in	in	IN
cord-277648-9kxwkcbl	368	25	single	single	JJ
cord-277648-9kxwkcbl	368	26	-	-	HYPH
cord-277648-9kxwkcbl	368	27	cell	cell	NN
cord-277648-9kxwkcbl	368	28	RNA	RNA	NNP
cord-277648-9kxwkcbl	368	29	sequencing	sequencing	NN
cord-277648-9kxwkcbl	368	30	data	datum	NNS
cord-277648-9kxwkcbl	368	31	Gene	Gene	NNP
cord-277648-9kxwkcbl	368	32	set	set	VBD
cord-277648-9kxwkcbl	368	33	enrichment	enrichment	NN
cord-277648-9kxwkcbl	368	34	analysis	analysis	NN
cord-277648-9kxwkcbl	368	35	:	:	:
cord-277648-9kxwkcbl	368	36	A	a	DT
cord-277648-9kxwkcbl	368	37	knowledge	knowledge	NN
cord-277648-9kxwkcbl	368	38	-	-	HYPH
cord-277648-9kxwkcbl	368	39	based	base	VBN
cord-277648-9kxwkcbl	368	40	approach	approach	NN
cord-277648-9kxwkcbl	368	41	for	for	IN
cord-277648-9kxwkcbl	368	42	interpreting	interpret	VBG
cord-277648-9kxwkcbl	368	43	genomewide	genomewide	NNP
cord-277648-9kxwkcbl	368	44	expression	expression	NN
cord-277648-9kxwkcbl	368	45	profiles	profile	VBZ
cord-277648-9kxwkcbl	368	46	Fast	fast	JJ
cord-277648-9kxwkcbl	368	47	gene	gene	NN
cord-277648-9kxwkcbl	368	48	set	set	VBD
cord-277648-9kxwkcbl	368	49	enrichment	enrichment	NN
cord-277648-9kxwkcbl	368	50	analysis	analysis	NN
cord-277648-9kxwkcbl	368	51	Etiology	etiology	NN
cord-277648-9kxwkcbl	368	52	matters	matter	VBZ
cord-277648-9kxwkcbl	368	53	-Genomic	-genomic	VBP
cord-277648-9kxwkcbl	368	54	DNA	dna	NN
cord-277648-9kxwkcbl	368	55	Methylation	methylation	NN
cord-277648-9kxwkcbl	368	56	Patterns	pattern	NNS
cord-277648-9kxwkcbl	368	57	in	in	IN
cord-277648-9kxwkcbl	368	58	Three	Three	NNP
cord-277648-9kxwkcbl	368	59	Rat	Rat	NNP
cord-277648-9kxwkcbl	368	60	Models	Models	NNPS
cord-277648-9kxwkcbl	368	61	of	of	IN
cord-277648-9kxwkcbl	368	62	Pathway	Pathway	NNP
cord-277648-9kxwkcbl	368	63	enrichment	enrichment	NN
cord-277648-9kxwkcbl	368	64	analysis	analysis	NN
cord-277648-9kxwkcbl	368	65	and	and	CC
cord-277648-9kxwkcbl	368	66	visualization	visualization	NN
cord-277648-9kxwkcbl	368	67	of	of	IN
cord-277648-9kxwkcbl	368	68	omics	omics	NNP
cord-277648-9kxwkcbl	368	69	data	datum	NNS
cord-277648-9kxwkcbl	368	70	using	use	VBG
cord-277648-9kxwkcbl	368	71	g	g	NN
cord-277648-9kxwkcbl	368	72	:	:	:
cord-277648-9kxwkcbl	368	73	Profiler	profiler	NN
cord-277648-9kxwkcbl	368	74	,	,	,
cord-277648-9kxwkcbl	368	75	GSEA	GSEA	NNP
cord-277648-9kxwkcbl	368	76	,	,	,
cord-277648-9kxwkcbl	368	77	Cytoscape	Cytoscape	NNP
cord-277648-9kxwkcbl	368	78	and	and	CC
cord-277648-9kxwkcbl	368	79	EnrichmentMap	EnrichmentMap	NNP
cord-277648-9kxwkcbl	368	80	An	an	DT
cord-277648-9kxwkcbl	368	81	integrated	integrate	VBN
cord-277648-9kxwkcbl	368	82	encyclopedia	encyclopedia	NN
cord-277648-9kxwkcbl	368	83	of	of	IN
cord-277648-9kxwkcbl	368	84	DNA	dna	NN
cord-277648-9kxwkcbl	368	85	elements	element	NNS
cord-277648-9kxwkcbl	368	86	in	in	IN
cord-277648-9kxwkcbl	368	87	the	the	DT
cord-277648-9kxwkcbl	368	88	human	human	JJ
cord-277648-9kxwkcbl	368	89	genome	genome	NN
cord-277648-9kxwkcbl	368	90	ChEA	ChEA	NNP
cord-277648-9kxwkcbl	368	91	:	:	:
cord-277648-9kxwkcbl	368	92	transcription	transcription	NN
cord-277648-9kxwkcbl	368	93	factor	factor	NN
cord-277648-9kxwkcbl	368	94	regulation	regulation	NN
cord-277648-9kxwkcbl	368	95	inferred	infer	VBN
cord-277648-9kxwkcbl	368	96	from	from	IN
cord-277648-9kxwkcbl	368	97	integrating	integrate	VBG
cord-277648-9kxwkcbl	368	98	genome	genome	NN
cord-277648-9kxwkcbl	368	99	-	-	HYPH
cord-277648-9kxwkcbl	368	100	wide	wide	JJ
cord-277648-9kxwkcbl	368	101	ChIP	chip	NN
cord-277648-9kxwkcbl	368	102	-	-	HYPH
cord-277648-9kxwkcbl	368	103	X	x	NN
cord-277648-9kxwkcbl	368	104	experiments	experiment	NNS
cord-277648-9kxwkcbl	368	105	CellPhoneDB	CellPhoneDB	NNP
cord-277648-9kxwkcbl	368	106	:	:	:
cord-277648-9kxwkcbl	368	107	inferring	infer	VBG
cord-277648-9kxwkcbl	368	108	cell	cell	NN
cord-277648-9kxwkcbl	368	109	-	-	HYPH
cord-277648-9kxwkcbl	368	110	cell	cell	NN
cord-277648-9kxwkcbl	368	111	communication	communication	NN
cord-277648-9kxwkcbl	368	112	from	from	IN
cord-277648-9kxwkcbl	368	113	combined	combined	JJ
cord-277648-9kxwkcbl	368	114	expression	expression	NN
cord-277648-9kxwkcbl	368	115	of	of	IN
cord-277648-9kxwkcbl	368	116	multi	multi	JJ
cord-277648-9kxwkcbl	368	117	-	-	JJ
cord-277648-9kxwkcbl	368	118	subunit	subunit	JJ
cord-277648-9kxwkcbl	368	119	ligand	ligand	NN
cord-277648-9kxwkcbl	368	120	-	-	HYPH
cord-277648-9kxwkcbl	368	121	receptor	receptor	NN
cord-277648-9kxwkcbl	368	122	complexes	complex	NNS
cord-277648-9kxwkcbl	369	1	All	all	DT
cord-277648-9kxwkcbl	369	2	data	datum	NNS
cord-277648-9kxwkcbl	369	3	used	use	VBN
cord-277648-9kxwkcbl	369	4	in	in	IN
cord-277648-9kxwkcbl	369	5	the	the	DT
cord-277648-9kxwkcbl	369	6	study	study	NN
cord-277648-9kxwkcbl	369	7	are	be	VBP
cord-277648-9kxwkcbl	369	8	available	available	JJ
cord-277648-9kxwkcbl	369	9	in	in	IN
cord-277648-9kxwkcbl	369	10	the	the	DT
cord-277648-9kxwkcbl	369	11	GEO	GEO	NNP
cord-277648-9kxwkcbl	369	12	under	under	IN
cord-277648-9kxwkcbl	369	13	accession	accession	NN
cord-277648-9kxwkcbl	369	14	numbers	number	NNS
cord-277648-9kxwkcbl	369	15	GSE145926	GSE145926	NNPS
cord-277648-9kxwkcbl	369	16	,	,	,
cord-277648-9kxwkcbl	369	17	GSM3660650	GSM3660650	NNP
cord-277648-9kxwkcbl	369	18	,	,	,
cord-277648-9kxwkcbl	369	19	and	and	CC
cord-277648-9kxwkcbl	369	20	GSE150728	GSE150728	NNP
cord-277648-9kxwkcbl	369	21	.	.	.
cord-277648-9kxwkcbl	370	1	All	all	DT
cord-277648-9kxwkcbl	370	2	code	code	NN
cord-277648-9kxwkcbl	370	3	used	use	VBN
cord-277648-9kxwkcbl	370	4	for	for	IN
cord-277648-9kxwkcbl	370	5	analysis	analysis	NN
cord-277648-9kxwkcbl	370	6	will	will	MD
cord-277648-9kxwkcbl	370	7	be	be	VB
cord-277648-9kxwkcbl	370	8	made	make	VBN
cord-277648-9kxwkcbl	370	9	available	available	JJ
cord-277648-9kxwkcbl	370	10	in	in	IN
cord-277648-9kxwkcbl	370	11	a	a	DT
cord-277648-9kxwkcbl	370	12	public	public	JJ
cord-277648-9kxwkcbl	370	13	repository	repository	NN
cord-277648-9kxwkcbl	370	14	.	.	.
cord-277648-9kxwkcbl	370	15	 	 	_SP
cord-277648-9kxwkcbl	371	1	The	the	DT
cord-277648-9kxwkcbl	371	2	authors	author	NNS
cord-277648-9kxwkcbl	371	3	have	have	VBP
cord-277648-9kxwkcbl	371	4	no	no	DT
cord-277648-9kxwkcbl	371	5	conflict	conflict	NN
cord-277648-9kxwkcbl	371	6	of	of	IN
cord-277648-9kxwkcbl	371	7	interest	interest	NN
cord-277648-9kxwkcbl	371	8	to	to	TO
cord-277648-9kxwkcbl	371	9	declare	declare	VB
cord-277648-9kxwkcbl	371	10	.	.	.