id sid tid token lemma pos cord-321499-17n9tj70 1 1 key key JJ cord-321499-17n9tj70 1 2 : : : cord-321499-17n9tj70 1 3 cord-321499 cord-321499 NN cord-321499-17n9tj70 1 4 - - HYPH cord-321499-17n9tj70 1 5 17n9tj70 17n9tj70 CD cord-321499-17n9tj70 1 6 authors author NNS cord-321499-17n9tj70 1 7 : : : cord-321499-17n9tj70 1 8 Marini Marini NNP cord-321499-17n9tj70 1 9 , , , cord-321499-17n9tj70 1 10 John John NNP cord-321499-17n9tj70 1 11 J. J. NNP cord-321499-17n9tj70 1 12 ; ; : cord-321499-17n9tj70 1 13 Dellinger Dellinger NNP cord-321499-17n9tj70 1 14 , , , cord-321499-17n9tj70 1 15 R. R. NNP cord-321499-17n9tj70 1 16 Phillip Phillip NNP cord-321499-17n9tj70 1 17 ; ; : cord-321499-17n9tj70 1 18 Brodie Brodie NNP cord-321499-17n9tj70 1 19 , , , cord-321499-17n9tj70 1 20 Daniel Daniel NNP cord-321499-17n9tj70 1 21 title title NN cord-321499-17n9tj70 1 22 : : : cord-321499-17n9tj70 1 23 Integrating integrate VBG cord-321499-17n9tj70 1 24 the the DT cord-321499-17n9tj70 1 25 evidence evidence NN cord-321499-17n9tj70 1 26 : : : cord-321499-17n9tj70 1 27 confronting confront VBG cord-321499-17n9tj70 1 28 the the DT cord-321499-17n9tj70 1 29 COVID-19 covid-19 JJ cord-321499-17n9tj70 1 30 elephant elephant NN cord-321499-17n9tj70 1 31 date date NN cord-321499-17n9tj70 1 32 : : : cord-321499-17n9tj70 1 33 2020 2020 CD cord-321499-17n9tj70 1 34 - - HYPH cord-321499-17n9tj70 1 35 07 07 CD cord-321499-17n9tj70 1 36 - - HYPH cord-321499-17n9tj70 1 37 25 25 CD cord-321499-17n9tj70 1 38 journal journal NN cord-321499-17n9tj70 1 39 : : : cord-321499-17n9tj70 2 1 Intensive intensive JJ cord-321499-17n9tj70 2 2 Care care NN cord-321499-17n9tj70 2 3 Med Med NNP cord-321499-17n9tj70 2 4 DOI doi NN cord-321499-17n9tj70 2 5 : : : cord-321499-17n9tj70 2 6 10.1007 10.1007 CD cord-321499-17n9tj70 2 7 / / SYM cord-321499-17n9tj70 2 8 s00134 s00134 VBN cord-321499-17n9tj70 2 9 - - HYPH cord-321499-17n9tj70 2 10 020 020 CD cord-321499-17n9tj70 2 11 - - HYPH cord-321499-17n9tj70 2 12 06195-z 06195-z CD cord-321499-17n9tj70 3 1 sha sha NNP cord-321499-17n9tj70 3 2 : : : cord-321499-17n9tj70 3 3 b96c33c63c0e1e6644b75f2a3fe6736213283c3b b96c33c63c0e1e6644b75f2a3fe6736213283c3b NNP cord-321499-17n9tj70 3 4 doc_id doc_id CD cord-321499-17n9tj70 3 5 : : : cord-321499-17n9tj70 4 1 321499 321499 CD cord-321499-17n9tj70 4 2 cord_uid cord_uid NN cord-321499-17n9tj70 4 3 : : : cord-321499-17n9tj70 5 1 17n9tj70 17n9tj70 CD cord-321499-17n9tj70 5 2 nan nan NNP cord-321499-17n9tj70 5 3 Coronavirus Coronavirus NNP cord-321499-17n9tj70 5 4 disease disease NN cord-321499-17n9tj70 5 5 2019 2019 CD cord-321499-17n9tj70 5 6 ( ( -LRB- cord-321499-17n9tj70 5 7 COVID-19 COVID-19 NNP cord-321499-17n9tj70 5 8 ) ) -RRB- cord-321499-17n9tj70 5 9 is be VBZ cord-321499-17n9tj70 5 10 an an DT cord-321499-17n9tj70 5 11 unfamiliar unfamiliar JJ cord-321499-17n9tj70 5 12 illness illness NN cord-321499-17n9tj70 5 13 with with IN cord-321499-17n9tj70 5 14 potentially potentially RB cord-321499-17n9tj70 5 15 devastating devastating JJ cord-321499-17n9tj70 5 16 consequences consequence NNS cord-321499-17n9tj70 5 17 . . . cord-321499-17n9tj70 6 1 The the DT cord-321499-17n9tj70 6 2 pandemic pandemic NN cord-321499-17n9tj70 6 3 is be VBZ cord-321499-17n9tj70 6 4 unfolding unfold VBG cord-321499-17n9tj70 6 5 at at IN cord-321499-17n9tj70 6 6 different different JJ cord-321499-17n9tj70 6 7 rates rate NNS cord-321499-17n9tj70 6 8 with with IN cord-321499-17n9tj70 6 9 wide wide JJ cord-321499-17n9tj70 6 10 geographic geographic JJ cord-321499-17n9tj70 6 11 separation separation NN cord-321499-17n9tj70 6 12 and and CC cord-321499-17n9tj70 6 13 seemingly seemingly RB cord-321499-17n9tj70 6 14 erratic erratic JJ cord-321499-17n9tj70 6 15 expression expression NN cord-321499-17n9tj70 6 16 . . . cord-321499-17n9tj70 7 1 There there EX cord-321499-17n9tj70 7 2 is be VBZ cord-321499-17n9tj70 7 3 well well RB cord-321499-17n9tj70 7 4 - - HYPH cord-321499-17n9tj70 7 5 justified justify VBN cord-321499-17n9tj70 7 6 urgency urgency NN cord-321499-17n9tj70 7 7 to to TO cord-321499-17n9tj70 7 8 describe describe VB cord-321499-17n9tj70 7 9 the the DT cord-321499-17n9tj70 7 10 inconsistently inconsistently RB cord-321499-17n9tj70 7 11 expressed express VBN cord-321499-17n9tj70 7 12 features feature NNS cord-321499-17n9tj70 7 13 of of IN cord-321499-17n9tj70 7 14 this this DT cord-321499-17n9tj70 7 15 new new JJ cord-321499-17n9tj70 7 16 viral viral JJ cord-321499-17n9tj70 7 17 disease disease NN cord-321499-17n9tj70 7 18 and and CC cord-321499-17n9tj70 7 19 implement implement VB cord-321499-17n9tj70 7 20 strategies strategy NNS cord-321499-17n9tj70 7 21 to to TO cord-321499-17n9tj70 7 22 avoid avoid VB cord-321499-17n9tj70 7 23 and and CC cord-321499-17n9tj70 7 24 treat treat VB cord-321499-17n9tj70 7 25 it -PRON- PRP cord-321499-17n9tj70 7 26 [ [ -LRB- cord-321499-17n9tj70 7 27 1 1 CD cord-321499-17n9tj70 7 28 ] ] -RRB- cord-321499-17n9tj70 7 29 [ [ -LRB- cord-321499-17n9tj70 7 30 2 2 CD cord-321499-17n9tj70 7 31 ] ] -RRB- cord-321499-17n9tj70 7 32 [ [ -LRB- cord-321499-17n9tj70 7 33 3 3 CD cord-321499-17n9tj70 7 34 ] ] -RRB- cord-321499-17n9tj70 7 35 [ [ -LRB- cord-321499-17n9tj70 7 36 4 4 CD cord-321499-17n9tj70 7 37 ] ] -RRB- cord-321499-17n9tj70 7 38 . . . cord-321499-17n9tj70 8 1 Because because IN cord-321499-17n9tj70 8 2 COVID-19-related covid-19-related JJ cord-321499-17n9tj70 8 3 illness illness NN cord-321499-17n9tj70 8 4 is be VBZ cord-321499-17n9tj70 8 5 caused cause VBN cord-321499-17n9tj70 8 6 by by IN cord-321499-17n9tj70 8 7 a a DT cord-321499-17n9tj70 8 8 single single JJ cord-321499-17n9tj70 8 9 virus virus NN cord-321499-17n9tj70 8 10 , , , cord-321499-17n9tj70 8 11 it -PRON- PRP cord-321499-17n9tj70 8 12 seems seem VBZ cord-321499-17n9tj70 8 13 reasonable reasonable JJ cord-321499-17n9tj70 8 14 to to TO cord-321499-17n9tj70 8 15 assume assume VB cord-321499-17n9tj70 8 16 a a DT cord-321499-17n9tj70 8 17 degree degree NN cord-321499-17n9tj70 8 18 of of IN cord-321499-17n9tj70 8 19 uniformity uniformity NN cord-321499-17n9tj70 8 20 across across IN cord-321499-17n9tj70 8 21 populations population NNS cord-321499-17n9tj70 8 22 . . . cord-321499-17n9tj70 9 1 Yet yet CC cord-321499-17n9tj70 9 2 , , , cord-321499-17n9tj70 9 3 some some DT cord-321499-17n9tj70 9 4 observations observation NNS cord-321499-17n9tj70 9 5 are be VBP cord-321499-17n9tj70 9 6 universal universal JJ cord-321499-17n9tj70 9 7 while while IN cord-321499-17n9tj70 9 8 others other NNS cord-321499-17n9tj70 9 9 apparently apparently RB cord-321499-17n9tj70 9 10 conflict conflict NN cord-321499-17n9tj70 9 11 . . . cord-321499-17n9tj70 10 1 In in IN cord-321499-17n9tj70 10 2 this this DT cord-321499-17n9tj70 10 3 urgent urgent JJ cord-321499-17n9tj70 10 4 situation situation NN cord-321499-17n9tj70 10 5 , , , cord-321499-17n9tj70 10 6 we -PRON- PRP cord-321499-17n9tj70 10 7 feel feel VBP cord-321499-17n9tj70 10 8 impelled impel VBN cord-321499-17n9tj70 10 9 to to TO cord-321499-17n9tj70 10 10 skip skip VB cord-321499-17n9tj70 10 11 steps step NNS cord-321499-17n9tj70 10 12 in in IN cord-321499-17n9tj70 10 13 the the DT cord-321499-17n9tj70 10 14 traditional traditional JJ cord-321499-17n9tj70 10 15 methodology methodology NN cord-321499-17n9tj70 10 16 of of IN cord-321499-17n9tj70 10 17 first first JJ cord-321499-17n9tj70 10 18 making make VBG cord-321499-17n9tj70 10 19 careful careful JJ cord-321499-17n9tj70 10 20 observations observation NNS cord-321499-17n9tj70 10 21 and and CC cord-321499-17n9tj70 10 22 then then RB cord-321499-17n9tj70 10 23 conducting conduct VBG cord-321499-17n9tj70 10 24 evidence evidence NN cord-321499-17n9tj70 10 25 - - HYPH cord-321499-17n9tj70 10 26 building build VBG cord-321499-17n9tj70 10 27 research research NN cord-321499-17n9tj70 10 28 to to TO cord-321499-17n9tj70 10 29 inform inform VB cord-321499-17n9tj70 10 30 rational rational JJ cord-321499-17n9tj70 10 31 management management NN cord-321499-17n9tj70 10 32 . . . cord-321499-17n9tj70 11 1 We -PRON- PRP cord-321499-17n9tj70 11 2 have have VBP cord-321499-17n9tj70 11 3 been be VBN cord-321499-17n9tj70 11 4 down down IN cord-321499-17n9tj70 11 5 this this DT cord-321499-17n9tj70 11 6 road road NN cord-321499-17n9tj70 11 7 before before RB cord-321499-17n9tj70 11 8 of of IN cord-321499-17n9tj70 11 9 needing need VBG cord-321499-17n9tj70 11 10 to to TO cord-321499-17n9tj70 11 11 act act VB cord-321499-17n9tj70 11 12 while while IN cord-321499-17n9tj70 11 13 not not RB cord-321499-17n9tj70 11 14 fully fully RB cord-321499-17n9tj70 11 15 understanding understand VBG cord-321499-17n9tj70 11 16 a a DT cord-321499-17n9tj70 11 17 new new JJ cord-321499-17n9tj70 11 18 pathogen pathogen NN cord-321499-17n9tj70 11 19 variant variant NN cord-321499-17n9tj70 11 20 . . . cord-321499-17n9tj70 12 1 But but CC cord-321499-17n9tj70 12 2 this this DT cord-321499-17n9tj70 12 3 SARS SARS NNP cord-321499-17n9tj70 12 4 - - HYPH cord-321499-17n9tj70 12 5 CoV-2 CoV-2 NNP cord-321499-17n9tj70 12 6 / / SYM cord-321499-17n9tj70 12 7 COVID-19 COVID-19 NNP cord-321499-17n9tj70 12 8 seems seem VBZ cord-321499-17n9tj70 12 9 different different JJ cord-321499-17n9tj70 12 10 . . . cord-321499-17n9tj70 13 1 This this DT cord-321499-17n9tj70 13 2 time time NN cord-321499-17n9tj70 13 3 around around RB cord-321499-17n9tj70 13 4 , , , cord-321499-17n9tj70 13 5 the the DT cord-321499-17n9tj70 13 6 disease disease NN cord-321499-17n9tj70 13 7 may may MD cord-321499-17n9tj70 13 8 infect infect VB cord-321499-17n9tj70 13 9 anyone anyone NN cord-321499-17n9tj70 13 10 and and CC cord-321499-17n9tj70 13 11 most most JJS cord-321499-17n9tj70 13 12 organ organ NN cord-321499-17n9tj70 13 13 systems system NNS cord-321499-17n9tj70 13 14 and and CC cord-321499-17n9tj70 13 15 is be VBZ cord-321499-17n9tj70 13 16 readily readily RB cord-321499-17n9tj70 13 17 and and CC cord-321499-17n9tj70 13 18 rapidly rapidly RB cord-321499-17n9tj70 13 19 transmitted transmit VBN cord-321499-17n9tj70 13 20 . . . cord-321499-17n9tj70 14 1 We -PRON- PRP cord-321499-17n9tj70 14 2 have have VBP cord-321499-17n9tj70 14 3 a a DT cord-321499-17n9tj70 14 4 right right NN cord-321499-17n9tj70 14 5 to to TO cord-321499-17n9tj70 14 6 be be VB cord-321499-17n9tj70 14 7 frightened frighten VBN cord-321499-17n9tj70 14 8 of of IN cord-321499-17n9tj70 14 9 this this DT cord-321499-17n9tj70 14 10 novel novel JJ cord-321499-17n9tj70 14 11 virus virus NN cord-321499-17n9tj70 14 12 . . . cord-321499-17n9tj70 15 1 Mastering master VBG cord-321499-17n9tj70 15 2 the the DT cord-321499-17n9tj70 15 3 entirety entirety NN cord-321499-17n9tj70 15 4 of of IN cord-321499-17n9tj70 15 5 medicine medicine NN cord-321499-17n9tj70 15 6 is be VBZ cord-321499-17n9tj70 15 7 impossible impossible JJ cord-321499-17n9tj70 15 8 ; ; : cord-321499-17n9tj70 15 9 practicing practice VBG cord-321499-17n9tj70 15 10 doctors doctor NNS cord-321499-17n9tj70 15 11 are be VBP cord-321499-17n9tj70 15 12 trained train VBN cord-321499-17n9tj70 15 13 to to TO cord-321499-17n9tj70 15 14 diagnose diagnose VB cord-321499-17n9tj70 15 15 ( ( -LRB- cord-321499-17n9tj70 15 16 label label NN cord-321499-17n9tj70 15 17 ) ) -RRB- cord-321499-17n9tj70 15 18 by by IN cord-321499-17n9tj70 15 19 interpreting interpret VBG cord-321499-17n9tj70 15 20 observations observation NNS cord-321499-17n9tj70 15 21 using use VBG cord-321499-17n9tj70 15 22 their -PRON- PRP$ cord-321499-17n9tj70 15 23 prior prior JJ cord-321499-17n9tj70 15 24 education education NN cord-321499-17n9tj70 15 25 and and CC cord-321499-17n9tj70 15 26 experience experience NN cord-321499-17n9tj70 15 27 , , , cord-321499-17n9tj70 15 28 and and CC cord-321499-17n9tj70 15 29 then then RB cord-321499-17n9tj70 15 30 manage manage VB cord-321499-17n9tj70 15 31 on on IN cord-321499-17n9tj70 15 32 that that DT cord-321499-17n9tj70 15 33 basis basis NN cord-321499-17n9tj70 15 34 . . . cord-321499-17n9tj70 16 1 We -PRON- PRP cord-321499-17n9tj70 16 2 have have VBP cord-321499-17n9tj70 16 3 a a DT cord-321499-17n9tj70 16 4 natural natural JJ cord-321499-17n9tj70 16 5 tendency tendency NN cord-321499-17n9tj70 16 6 to to TO cord-321499-17n9tj70 16 7 ' ' `` cord-321499-17n9tj70 16 8 force force NN cord-321499-17n9tj70 16 9 - - HYPH cord-321499-17n9tj70 16 10 fit fit NN cord-321499-17n9tj70 16 11 ' ' '' cord-321499-17n9tj70 16 12 newly newly RB cord-321499-17n9tj70 16 13 encountered encounter VBN cord-321499-17n9tj70 16 14 fragments fragment NNS cord-321499-17n9tj70 16 15 of of IN cord-321499-17n9tj70 16 16 unfamiliar unfamiliar JJ cord-321499-17n9tj70 16 17 information information NN cord-321499-17n9tj70 16 18 into into IN cord-321499-17n9tj70 16 19 our -PRON- PRP$ cord-321499-17n9tj70 16 20 existing exist VBG cord-321499-17n9tj70 16 21 constructs construct NNS cord-321499-17n9tj70 16 22 and and CC cord-321499-17n9tj70 16 23 understandings understanding NNS cord-321499-17n9tj70 16 24 . . . cord-321499-17n9tj70 17 1 ( ( -LRB- cord-321499-17n9tj70 17 2 In in IN cord-321499-17n9tj70 17 3 psychology psychology NN cord-321499-17n9tj70 17 4 , , , cord-321499-17n9tj70 17 5 this this DT cord-321499-17n9tj70 17 6 is be VBZ cord-321499-17n9tj70 17 7 known know VBN cord-321499-17n9tj70 17 8 as as IN cord-321499-17n9tj70 17 9 the the DT cord-321499-17n9tj70 17 10 Barnum Barnum NNP cord-321499-17n9tj70 17 11 effect effect NN cord-321499-17n9tj70 17 12 [ [ -LRB- cord-321499-17n9tj70 17 13 5 5 CD cord-321499-17n9tj70 17 14 ] ] -RRB- cord-321499-17n9tj70 17 15 . . . cord-321499-17n9tj70 17 16 ) ) -RRB- cord-321499-17n9tj70 18 1 Although although IN cord-321499-17n9tj70 18 2 usually usually RB cord-321499-17n9tj70 18 3 a a DT cord-321499-17n9tj70 18 4 functional functional JJ cord-321499-17n9tj70 18 5 approach approach NN cord-321499-17n9tj70 18 6 to to IN cord-321499-17n9tj70 18 7 decision decision NN cord-321499-17n9tj70 18 8 - - HYPH cord-321499-17n9tj70 18 9 making making NN cord-321499-17n9tj70 18 10 when when WRB cord-321499-17n9tj70 18 11 dealing deal VBG cord-321499-17n9tj70 18 12 with with IN cord-321499-17n9tj70 18 13 too too RB cord-321499-17n9tj70 18 14 little little JJ cord-321499-17n9tj70 18 15 information information NN cord-321499-17n9tj70 18 16 , , , cord-321499-17n9tj70 18 17 we -PRON- PRP cord-321499-17n9tj70 18 18 may may MD cord-321499-17n9tj70 18 19 unintentionally unintentionally RB cord-321499-17n9tj70 18 20 make make VB cord-321499-17n9tj70 18 21 errors error NNS cord-321499-17n9tj70 18 22 when when WRB cord-321499-17n9tj70 18 23 the the DT cord-321499-17n9tj70 18 24 disease disease NN cord-321499-17n9tj70 18 25 seems seem VBZ cord-321499-17n9tj70 18 26 as as IN cord-321499-17n9tj70 18 27 alien alien JJ cord-321499-17n9tj70 18 28 and and CC cord-321499-17n9tj70 18 29 multifaceted multifaceted JJ cord-321499-17n9tj70 18 30 as as IN cord-321499-17n9tj70 18 31 COVID-19 COVID-19 NNP cord-321499-17n9tj70 18 32 . . . cord-321499-17n9tj70 19 1 The the DT cord-321499-17n9tj70 19 2 acute acute JJ cord-321499-17n9tj70 19 3 respiratory respiratory JJ cord-321499-17n9tj70 19 4 distress distress NN cord-321499-17n9tj70 19 5 syndrome syndrome NN cord-321499-17n9tj70 19 6 ( ( -LRB- cord-321499-17n9tj70 19 7 ARDS ARDS NNP cord-321499-17n9tj70 19 8 ) ) -RRB- cord-321499-17n9tj70 19 9 that that WDT cord-321499-17n9tj70 19 10 figures figure VBZ cord-321499-17n9tj70 19 11 so so RB cord-321499-17n9tj70 19 12 prominently prominently RB cord-321499-17n9tj70 19 13 in in IN cord-321499-17n9tj70 19 14 severe severe JJ cord-321499-17n9tj70 19 15 cases case NNS cord-321499-17n9tj70 19 16 of of IN cord-321499-17n9tj70 19 17 COVID covid JJ cord-321499-17n9tj70 19 18 infection infection NN cord-321499-17n9tj70 19 19 may may MD cord-321499-17n9tj70 19 20 seem seem VB cord-321499-17n9tj70 19 21 familiar familiar JJ cord-321499-17n9tj70 19 22 but but CC cord-321499-17n9tj70 19 23 has have VBZ cord-321499-17n9tj70 19 24 historically historically RB cord-321499-17n9tj70 19 25 predisposed predisposed JJ cord-321499-17n9tj70 19 26 to to IN cord-321499-17n9tj70 19 27 such such JJ cord-321499-17n9tj70 19 28 logical logical JJ cord-321499-17n9tj70 19 29 missteps misstep NNS cord-321499-17n9tj70 19 30 [ [ -LRB- cord-321499-17n9tj70 19 31 6 6 CD cord-321499-17n9tj70 19 32 ] ] -RRB- cord-321499-17n9tj70 19 33 . . . cord-321499-17n9tj70 20 1 ARDS ARDS NNP cord-321499-17n9tj70 20 2 itself -PRON- PRP cord-321499-17n9tj70 20 3 was be VBD cord-321499-17n9tj70 20 4 originally originally RB cord-321499-17n9tj70 20 5 perceived perceive VBN cord-321499-17n9tj70 20 6 as as IN cord-321499-17n9tj70 20 7 a a DT cord-321499-17n9tj70 20 8 high high JJ cord-321499-17n9tj70 20 9 permeability permeability NN cord-321499-17n9tj70 20 10 edema edema NN cord-321499-17n9tj70 20 11 and and CC cord-321499-17n9tj70 20 12 low low JJ cord-321499-17n9tj70 20 13 lung lung NN cord-321499-17n9tj70 20 14 compliance compliance NN cord-321499-17n9tj70 20 15 condition condition NN cord-321499-17n9tj70 20 16 that that WDT cord-321499-17n9tj70 20 17 disrupted disrupt VBD cord-321499-17n9tj70 20 18 function function NN cord-321499-17n9tj70 20 19 of of IN cord-321499-17n9tj70 20 20 all all DT cord-321499-17n9tj70 20 21 alveolar alveolar JJ cord-321499-17n9tj70 20 22 units unit NNS cord-321499-17n9tj70 20 23 and and CC cord-321499-17n9tj70 20 24 resulted result VBD cord-321499-17n9tj70 20 25 primarily primarily RB cord-321499-17n9tj70 20 26 from from IN cord-321499-17n9tj70 20 27 surfactant surfactant NN cord-321499-17n9tj70 20 28 deficiency deficiency NN cord-321499-17n9tj70 20 29 [ [ -LRB- cord-321499-17n9tj70 20 30 7 7 CD cord-321499-17n9tj70 20 31 ] ] -RRB- cord-321499-17n9tj70 20 32 . . . cord-321499-17n9tj70 21 1 Cause cause VB cord-321499-17n9tj70 21 2 and and CC cord-321499-17n9tj70 21 3 histologic histologic JJ cord-321499-17n9tj70 21 4 manifestations manifestation NNS cord-321499-17n9tj70 21 5 went go VBD cord-321499-17n9tj70 21 6 hand hand NN cord-321499-17n9tj70 21 7 - - HYPH cord-321499-17n9tj70 21 8 inhand inhand NN cord-321499-17n9tj70 21 9 . . . cord-321499-17n9tj70 22 1 This this DT cord-321499-17n9tj70 22 2 simple simple JJ cord-321499-17n9tj70 22 3 perception perception NN cord-321499-17n9tj70 22 4 provided provide VBN cord-321499-17n9tj70 22 5 for for IN cord-321499-17n9tj70 22 6 adult adult NN cord-321499-17n9tj70 22 7 patients patient NNS cord-321499-17n9tj70 22 8 a a DT cord-321499-17n9tj70 22 9 convenient convenient JJ cord-321499-17n9tj70 22 10 explanation explanation NN cord-321499-17n9tj70 22 11 that that WDT cord-321499-17n9tj70 22 12 paralleled parallel VBD cord-321499-17n9tj70 22 13 that that DT cord-321499-17n9tj70 22 14 of of IN cord-321499-17n9tj70 22 15 the the DT cord-321499-17n9tj70 22 16 infant infant NN cord-321499-17n9tj70 22 17 respiratory respiratory JJ cord-321499-17n9tj70 22 18 distress distress NN cord-321499-17n9tj70 22 19 syndrome syndrome NN cord-321499-17n9tj70 22 20 , , , cord-321499-17n9tj70 22 21 a a DT cord-321499-17n9tj70 22 22 condition condition NN cord-321499-17n9tj70 22 23 for for IN cord-321499-17n9tj70 22 24 which which WDT cord-321499-17n9tj70 22 25 the the DT cord-321499-17n9tj70 22 26 root root NN cord-321499-17n9tj70 22 27 cause cause NN cord-321499-17n9tj70 22 28 mechanism mechanism NN cord-321499-17n9tj70 22 29 had have VBD cord-321499-17n9tj70 22 30 already already RB cord-321499-17n9tj70 22 31 been be VBN cord-321499-17n9tj70 22 32 confirmed confirm VBN cord-321499-17n9tj70 22 33 [ [ -LRB- cord-321499-17n9tj70 22 34 8 8 CD cord-321499-17n9tj70 22 35 ] ] -RRB- cord-321499-17n9tj70 22 36 . . . cord-321499-17n9tj70 23 1 Indeed indeed RB cord-321499-17n9tj70 23 2 , , , cord-321499-17n9tj70 23 3 for for IN cord-321499-17n9tj70 23 4 some some DT cord-321499-17n9tj70 23 5 years year NNS cord-321499-17n9tj70 23 6 after after IN cord-321499-17n9tj70 23 7 its -PRON- PRP$ cord-321499-17n9tj70 23 8 initial initial JJ cord-321499-17n9tj70 23 9 description description NN cord-321499-17n9tj70 23 10 , , , cord-321499-17n9tj70 23 11 the the DT cord-321499-17n9tj70 23 12 designation designation NN cord-321499-17n9tj70 23 13 of of IN cord-321499-17n9tj70 23 14 ' ' `` cord-321499-17n9tj70 23 15 Adult Adult NNP cord-321499-17n9tj70 23 16 Respiratory Respiratory NNP cord-321499-17n9tj70 23 17 Distress Distress NNP cord-321499-17n9tj70 23 18 ' ' '' cord-321499-17n9tj70 23 19 reflected reflect VBD cord-321499-17n9tj70 23 20 this this DT cord-321499-17n9tj70 23 21 flawed flawed JJ cord-321499-17n9tj70 23 22 theory theory NN cord-321499-17n9tj70 23 23 of of IN cord-321499-17n9tj70 23 24 cause cause NN cord-321499-17n9tj70 23 25 and and CC cord-321499-17n9tj70 23 26 effect effect NN cord-321499-17n9tj70 23 27 . . . cord-321499-17n9tj70 24 1 More more RBR cord-321499-17n9tj70 24 2 recently recently RB cord-321499-17n9tj70 24 3 , , , cord-321499-17n9tj70 24 4 considerations consideration NNS cord-321499-17n9tj70 24 5 of of IN cord-321499-17n9tj70 24 6 lung lung NN cord-321499-17n9tj70 24 7 compliance compliance NN cord-321499-17n9tj70 24 8 and and CC cord-321499-17n9tj70 24 9 underlying underlying JJ cord-321499-17n9tj70 24 10 pathology pathology NN cord-321499-17n9tj70 24 11 have have VBP cord-321499-17n9tj70 24 12 yielded yield VBN cord-321499-17n9tj70 24 13 to to IN cord-321499-17n9tj70 24 14 a a DT cord-321499-17n9tj70 24 15 broader broad JJR cord-321499-17n9tj70 24 16 definition definition NN cord-321499-17n9tj70 24 17 of of IN cord-321499-17n9tj70 24 18 ARDS ARDS NNP cord-321499-17n9tj70 24 19 based base VBN cord-321499-17n9tj70 24 20 on on IN cord-321499-17n9tj70 24 21 a a DT cord-321499-17n9tj70 24 22 relatively relatively RB cord-321499-17n9tj70 24 23 acute acute JJ cord-321499-17n9tj70 24 24 onset onset NN cord-321499-17n9tj70 24 25 of of IN cord-321499-17n9tj70 24 26 a a DT cord-321499-17n9tj70 24 27 known know VBN cord-321499-17n9tj70 24 28 precipitant precipitant NN cord-321499-17n9tj70 24 29 that that WDT cord-321499-17n9tj70 24 30 impairs impair VBZ cord-321499-17n9tj70 24 31 oxygenation oxygenation NN cord-321499-17n9tj70 24 32 and and CC cord-321499-17n9tj70 24 33 produces produce VBZ cord-321499-17n9tj70 24 34 otherwise otherwise RB cord-321499-17n9tj70 24 35 unexplained unexplained JJ cord-321499-17n9tj70 24 36 multi multi JJ cord-321499-17n9tj70 24 37 - - JJ cord-321499-17n9tj70 24 38 lobar lobar JJ cord-321499-17n9tj70 24 39 infiltrates infiltrate VBZ cord-321499-17n9tj70 24 40 [ [ -LRB- cord-321499-17n9tj70 24 41 9 9 CD cord-321499-17n9tj70 24 42 ] ] -RRB- cord-321499-17n9tj70 24 43 . . . cord-321499-17n9tj70 25 1 Airspace airspace NN cord-321499-17n9tj70 25 2 flooding flooding NN cord-321499-17n9tj70 25 3 , , , cord-321499-17n9tj70 25 4 collapse collapse NN cord-321499-17n9tj70 25 5 , , , cord-321499-17n9tj70 25 6 and and CC cord-321499-17n9tj70 25 7 consolidation consolidation NN cord-321499-17n9tj70 25 8 are be VBP cord-321499-17n9tj70 25 9 envisioned envision VBN cord-321499-17n9tj70 25 10 to to IN cord-321499-17n9tj70 25 11 parallel parallel VB cord-321499-17n9tj70 25 12 ( ( -LRB- cord-321499-17n9tj70 25 13 more more RBR cord-321499-17n9tj70 25 14 or or CC cord-321499-17n9tj70 25 15 less less RBR cord-321499-17n9tj70 25 16 ) ) -RRB- cord-321499-17n9tj70 26 1 the the DT cord-321499-17n9tj70 26 2 severity severity NN cord-321499-17n9tj70 26 3 of of IN cord-321499-17n9tj70 26 4 oxygenation oxygenation NN cord-321499-17n9tj70 26 5 impairment impairment NN cord-321499-17n9tj70 26 6 [ [ -LRB- cord-321499-17n9tj70 26 7 9 9 CD cord-321499-17n9tj70 26 8 , , , cord-321499-17n9tj70 26 9 10 10 CD cord-321499-17n9tj70 26 10 ] ] -RRB- cord-321499-17n9tj70 26 11 . . . cord-321499-17n9tj70 27 1 Most most RBS cord-321499-17n9tj70 27 2 often often RB cord-321499-17n9tj70 27 3 , , , cord-321499-17n9tj70 27 4 this this DT cord-321499-17n9tj70 27 5 view view NN cord-321499-17n9tj70 27 6 serves serve VBZ cord-321499-17n9tj70 27 7 reasonably reasonably RB cord-321499-17n9tj70 27 8 well well RB cord-321499-17n9tj70 27 9 . . . cord-321499-17n9tj70 28 1 As as IN cord-321499-17n9tj70 28 2 pathologic pathologic JJ cord-321499-17n9tj70 28 3 severity severity NN cord-321499-17n9tj70 28 4 increases increase NNS cord-321499-17n9tj70 28 5 , , , cord-321499-17n9tj70 28 6 key key JJ cord-321499-17n9tj70 28 7 definitional definitional JJ cord-321499-17n9tj70 28 8 features feature NNS cord-321499-17n9tj70 28 9 of of IN cord-321499-17n9tj70 28 10 ARDS ARDS NNP cord-321499-17n9tj70 28 11 ( ( -LRB- cord-321499-17n9tj70 28 12 extensive extensive JJ cord-321499-17n9tj70 28 13 infiltrates infiltrate NNS cord-321499-17n9tj70 28 14 , , , cord-321499-17n9tj70 28 15 hypoxemia hypoxemia NN cord-321499-17n9tj70 28 16 ) ) -RRB- cord-321499-17n9tj70 28 17 usually usually RB cord-321499-17n9tj70 28 18 proceed proceed VBP cord-321499-17n9tj70 28 19 in in IN cord-321499-17n9tj70 28 20 synch synch NN cord-321499-17n9tj70 28 21 , , , cord-321499-17n9tj70 28 22 serving serve VBG cord-321499-17n9tj70 28 23 to to TO cord-321499-17n9tj70 28 24 guide guide VB cord-321499-17n9tj70 28 25 clinical clinical JJ cord-321499-17n9tj70 28 26 treatment treatment NN cord-321499-17n9tj70 28 27 and and CC cord-321499-17n9tj70 28 28 prognosis prognosis NN cord-321499-17n9tj70 28 29 by by IN cord-321499-17n9tj70 28 30 gas gas NN cord-321499-17n9tj70 28 31 exchange exchange NN cord-321499-17n9tj70 28 32 criteria criterion NNS cord-321499-17n9tj70 28 33 . . . cord-321499-17n9tj70 29 1 Accordingly accordingly RB cord-321499-17n9tj70 29 2 , , , cord-321499-17n9tj70 29 3 choices choice NNS cord-321499-17n9tj70 29 4 for for IN cord-321499-17n9tj70 29 5 positive positive JJ cord-321499-17n9tj70 29 6 end end NN cord-321499-17n9tj70 29 7 - - HYPH cord-321499-17n9tj70 29 8 expiratory expiratory NN cord-321499-17n9tj70 29 9 pressure pressure NN cord-321499-17n9tj70 29 10 ( ( -LRB- cord-321499-17n9tj70 29 11 PEEP PEEP NNP cord-321499-17n9tj70 29 12 ) ) -RRB- cord-321499-17n9tj70 29 13 , , , cord-321499-17n9tj70 29 14 tidal tidal JJ cord-321499-17n9tj70 29 15 volume volume NN cord-321499-17n9tj70 29 16 , , , cord-321499-17n9tj70 29 17 and and CC cord-321499-17n9tj70 29 18 prone prone JJ cord-321499-17n9tj70 29 19 positioning positioning NN cord-321499-17n9tj70 29 20 are be VBP cord-321499-17n9tj70 29 21 made make VBN cord-321499-17n9tj70 29 22 with with IN cord-321499-17n9tj70 29 23 the the DT cord-321499-17n9tj70 29 24 intention intention NN cord-321499-17n9tj70 29 25 of of IN cord-321499-17n9tj70 29 26 improving improve VBG cord-321499-17n9tj70 29 27 oxygenation oxygenation NN cord-321499-17n9tj70 29 28 and and CC cord-321499-17n9tj70 29 29 recruiting recruit VBG cord-321499-17n9tj70 29 30 lung lung NN cord-321499-17n9tj70 29 31 units unit NNS cord-321499-17n9tj70 29 32 while while IN cord-321499-17n9tj70 29 33 avoiding avoid VBG cord-321499-17n9tj70 29 34 ventilator ventilator NN cord-321499-17n9tj70 29 35 - - HYPH cord-321499-17n9tj70 29 36 induced induce VBN cord-321499-17n9tj70 29 37 lung lung NN cord-321499-17n9tj70 29 38 injury injury NN cord-321499-17n9tj70 29 39 ( ( -LRB- cord-321499-17n9tj70 29 40 VILI VILI NNP cord-321499-17n9tj70 29 41 ) ) -RRB- cord-321499-17n9tj70 29 42 . . . cord-321499-17n9tj70 30 1 Clinical clinical JJ cord-321499-17n9tj70 30 2 trials trial NNS cord-321499-17n9tj70 30 3 and and CC cord-321499-17n9tj70 30 4 guideline guideline NN cord-321499-17n9tj70 30 5 tables table NNS cord-321499-17n9tj70 30 6 for for IN cord-321499-17n9tj70 30 7 mechanical mechanical JJ cord-321499-17n9tj70 30 8 ventilation ventilation NN cord-321499-17n9tj70 30 9 in in IN cord-321499-17n9tj70 30 10 ARDS ARDS NNP cord-321499-17n9tj70 30 11 are be VBP cord-321499-17n9tj70 30 12 , , , cord-321499-17n9tj70 30 13 for for IN cord-321499-17n9tj70 30 14 better well JJR cord-321499-17n9tj70 30 15 or or CC cord-321499-17n9tj70 30 16 worse bad JJR cord-321499-17n9tj70 30 17 , , , cord-321499-17n9tj70 30 18 keyed key VBN cord-321499-17n9tj70 30 19 to to IN cord-321499-17n9tj70 30 20 the the DT cord-321499-17n9tj70 30 21 severity severity NN cord-321499-17n9tj70 30 22 of of IN cord-321499-17n9tj70 30 23 oxygenation oxygenation NN cord-321499-17n9tj70 30 24 deficit deficit NN cord-321499-17n9tj70 30 25 [ [ -LRB- cord-321499-17n9tj70 30 26 11 11 CD cord-321499-17n9tj70 30 27 ] ] -RRB- cord-321499-17n9tj70 30 28 . . . cord-321499-17n9tj70 31 1 At at IN cord-321499-17n9tj70 31 2 the the DT cord-321499-17n9tj70 31 3 bedside bedside NN cord-321499-17n9tj70 31 4 , , , cord-321499-17n9tj70 31 5 VILI VILI NNP cord-321499-17n9tj70 31 6 risk risk NN cord-321499-17n9tj70 31 7 is be VBZ cord-321499-17n9tj70 31 8 * * NFP cord-321499-17n9tj70 31 9 Correspondence correspondence NN cord-321499-17n9tj70 31 10 : : : cord-321499-17n9tj70 31 11 marin002@umn.edu marin002@umn.edu NNP cord-321499-17n9tj70 31 12 indexed index VBN cord-321499-17n9tj70 31 13 by by IN cord-321499-17n9tj70 31 14 plateau plateau NN cord-321499-17n9tj70 31 15 pressure pressure NN cord-321499-17n9tj70 31 16 , , , cord-321499-17n9tj70 31 17 driving drive VBG cord-321499-17n9tj70 31 18 pressure pressure NN cord-321499-17n9tj70 31 19 , , , cord-321499-17n9tj70 31 20 and and CC cord-321499-17n9tj70 31 21 more more RBR cord-321499-17n9tj70 31 22 recently recently RB cord-321499-17n9tj70 31 23 by by IN cord-321499-17n9tj70 31 24 mechanical mechanical JJ cord-321499-17n9tj70 31 25 power power NN cord-321499-17n9tj70 31 26 [ [ -LRB- cord-321499-17n9tj70 31 27 12 12 CD cord-321499-17n9tj70 31 28 ] ] -RRB- cord-321499-17n9tj70 31 29 . . . cord-321499-17n9tj70 32 1 Certain certain JJ cord-321499-17n9tj70 32 2 features feature NNS cord-321499-17n9tj70 32 3 of of IN cord-321499-17n9tj70 32 4 COVID-19-associated COVID-19-associated NNP cord-321499-17n9tj70 32 5 ARDS ARDS NNP cord-321499-17n9tj70 32 6 ( ( -LRB- cord-321499-17n9tj70 32 7 what what WP cord-321499-17n9tj70 32 8 has have VBZ cord-321499-17n9tj70 32 9 been be VBN cord-321499-17n9tj70 32 10 termed term VBN cord-321499-17n9tj70 32 11 " " `` cord-321499-17n9tj70 32 12 CARDS card NNS cord-321499-17n9tj70 32 13 " " '' cord-321499-17n9tj70 32 14 ) ) -RRB- cord-321499-17n9tj70 32 15 seem seem VBP cord-321499-17n9tj70 32 16 to to TO cord-321499-17n9tj70 32 17 challenge challenge VB cord-321499-17n9tj70 32 18 that that DT cord-321499-17n9tj70 32 19 useful useful JJ cord-321499-17n9tj70 32 20 conceptual conceptual JJ cord-321499-17n9tj70 32 21 framework framework NN cord-321499-17n9tj70 32 22 . . . cord-321499-17n9tj70 33 1 Specifically specifically RB cord-321499-17n9tj70 33 2 , , , cord-321499-17n9tj70 33 3 lung lung NN cord-321499-17n9tj70 33 4 compliance compliance NN cord-321499-17n9tj70 33 5 may may MD cord-321499-17n9tj70 33 6 be be VB cord-321499-17n9tj70 33 7 well well RB cord-321499-17n9tj70 33 8 preserved preserve VBN cord-321499-17n9tj70 33 9 in in IN cord-321499-17n9tj70 33 10 the the DT cord-321499-17n9tj70 33 11 early early JJ cord-321499-17n9tj70 33 12 and and CC cord-321499-17n9tj70 33 13 mild mild JJ cord-321499-17n9tj70 33 14 stages stage NNS cord-321499-17n9tj70 33 15 of of IN cord-321499-17n9tj70 33 16 CARDS card NNS cord-321499-17n9tj70 33 17 ( ( -LRB- cord-321499-17n9tj70 33 18 at at IN cord-321499-17n9tj70 33 19 least least JJS cord-321499-17n9tj70 33 20 in in IN cord-321499-17n9tj70 33 21 a a DT cord-321499-17n9tj70 33 22 subpopulation subpopulation NN cord-321499-17n9tj70 33 23 of of IN cord-321499-17n9tj70 33 24 these these DT cord-321499-17n9tj70 33 25 patients patient NNS cord-321499-17n9tj70 33 26 ) ) -RRB- cord-321499-17n9tj70 33 27 , , , cord-321499-17n9tj70 33 28 because because IN cord-321499-17n9tj70 33 29 severe severe JJ cord-321499-17n9tj70 33 30 hypoxemia hypoxemia NN cord-321499-17n9tj70 33 31 may may MD cord-321499-17n9tj70 33 32 not not RB cord-321499-17n9tj70 33 33 originate originate VB cord-321499-17n9tj70 33 34 at at IN cord-321499-17n9tj70 33 35 first first RB cord-321499-17n9tj70 33 36 primarily primarily RB cord-321499-17n9tj70 33 37 from from IN cord-321499-17n9tj70 33 38 airspace airspace NN cord-321499-17n9tj70 33 39 filling filling NN cord-321499-17n9tj70 33 40 and and CC cord-321499-17n9tj70 33 41 lung lung NN cord-321499-17n9tj70 33 42 unit unit NN cord-321499-17n9tj70 33 43 drop drop VB cord-321499-17n9tj70 33 44 - - HYPH cord-321499-17n9tj70 33 45 out out NN cord-321499-17n9tj70 33 46 - - : cord-321499-17n9tj70 33 47 though though IN cord-321499-17n9tj70 33 48 these these DT cord-321499-17n9tj70 33 49 do do VBP cord-321499-17n9tj70 33 50 occur occur VB cord-321499-17n9tj70 33 51 to to IN cord-321499-17n9tj70 33 52 some some DT cord-321499-17n9tj70 33 53 modest modest JJ cord-321499-17n9tj70 33 54 extent extent NN cord-321499-17n9tj70 33 55 - - : cord-321499-17n9tj70 33 56 but but CC cord-321499-17n9tj70 33 57 rather rather RB cord-321499-17n9tj70 33 58 from from IN cord-321499-17n9tj70 33 59 a a DT cord-321499-17n9tj70 33 60 microvascular microvascular JJ cord-321499-17n9tj70 33 61 attack attack NN cord-321499-17n9tj70 33 62 that that WDT cord-321499-17n9tj70 33 63 dysregulates dysregulate VBZ cord-321499-17n9tj70 33 64 ventilation ventilation NN cord-321499-17n9tj70 33 65 / / SYM cord-321499-17n9tj70 33 66 perfusion perfusion NN cord-321499-17n9tj70 33 67 matching matching NN cord-321499-17n9tj70 33 68 in in IN cord-321499-17n9tj70 33 69 well well RB cord-321499-17n9tj70 33 70 - - HYPH cord-321499-17n9tj70 33 71 ventilated ventilate VBN cord-321499-17n9tj70 33 72 lung lung NN cord-321499-17n9tj70 33 73 units unit NNS cord-321499-17n9tj70 33 74 and and CC cord-321499-17n9tj70 33 75 increases increase VBZ cord-321499-17n9tj70 33 76 dead dead JJ cord-321499-17n9tj70 33 77 space space NN cord-321499-17n9tj70 33 78 [ [ -LRB- cord-321499-17n9tj70 33 79 13 13 CD cord-321499-17n9tj70 33 80 ] ] -RRB- cord-321499-17n9tj70 33 81 . . . cord-321499-17n9tj70 34 1 When when WRB cord-321499-17n9tj70 34 2 simpler simple JJR cord-321499-17n9tj70 34 3 measures measure NNS cord-321499-17n9tj70 34 4 fail fail VBP cord-321499-17n9tj70 34 5 , , , cord-321499-17n9tj70 34 6 the the DT cord-321499-17n9tj70 34 7 familiar familiar JJ cord-321499-17n9tj70 34 8 initial initial JJ cord-321499-17n9tj70 34 9 response response NN cord-321499-17n9tj70 34 10 is be VBZ cord-321499-17n9tj70 34 11 to to TO cord-321499-17n9tj70 34 12 improve improve VB cord-321499-17n9tj70 34 13 oxygenation oxygenation NN cord-321499-17n9tj70 34 14 - - HYPH cord-321499-17n9tj70 34 15 use use NN cord-321499-17n9tj70 34 16 higher high JJR cord-321499-17n9tj70 34 17 PEEP peep NN cord-321499-17n9tj70 34 18 and and CC cord-321499-17n9tj70 34 19 lower low JJR cord-321499-17n9tj70 34 20 tidal tidal JJ cord-321499-17n9tj70 34 21 volumes volume NNS cord-321499-17n9tj70 34 22 , , , cord-321499-17n9tj70 34 23 offsetting offset VBG cord-321499-17n9tj70 34 24 any any DT cord-321499-17n9tj70 34 25 hemodynamic hemodynamic JJ cord-321499-17n9tj70 34 26 consequences consequence NNS cord-321499-17n9tj70 34 27 . . . cord-321499-17n9tj70 35 1 Yet yet CC cord-321499-17n9tj70 35 2 , , , cord-321499-17n9tj70 35 3 it -PRON- PRP cord-321499-17n9tj70 35 4 stands stand VBZ cord-321499-17n9tj70 35 5 to to IN cord-321499-17n9tj70 35 6 reason reason NN cord-321499-17n9tj70 35 7 ( ( -LRB- cord-321499-17n9tj70 35 8 though though IN cord-321499-17n9tj70 35 9 still still RB cord-321499-17n9tj70 35 10 unproven unproven JJ cord-321499-17n9tj70 35 11 ) ) -RRB- cord-321499-17n9tj70 35 12 that that IN cord-321499-17n9tj70 35 13 because because IN cord-321499-17n9tj70 35 14 these these DT cord-321499-17n9tj70 35 15 lungs lung NNS cord-321499-17n9tj70 35 16 are be VBP cord-321499-17n9tj70 35 17 initially initially RB cord-321499-17n9tj70 35 18 gas gas NN cord-321499-17n9tj70 35 19 filled fill VBN cord-321499-17n9tj70 35 20 and and CC cord-321499-17n9tj70 35 21 unexpectedly unexpectedly RB cord-321499-17n9tj70 35 22 flexible flexible JJ cord-321499-17n9tj70 35 23 for for IN cord-321499-17n9tj70 35 24 the the DT cord-321499-17n9tj70 35 25 severity severity NN cord-321499-17n9tj70 35 26 of of IN cord-321499-17n9tj70 35 27 hypoxemia hypoxemia NN cord-321499-17n9tj70 35 28 , , , cord-321499-17n9tj70 35 29 such such JJ cord-321499-17n9tj70 35 30 actions action NNS cord-321499-17n9tj70 35 31 might may MD cord-321499-17n9tj70 35 32 needlessly needlessly RB cord-321499-17n9tj70 35 33 accentuate accentuate VB cord-321499-17n9tj70 35 34 the the DT cord-321499-17n9tj70 35 35 underlying underlying JJ cord-321499-17n9tj70 35 36 problem problem NN cord-321499-17n9tj70 35 37 and and CC cord-321499-17n9tj70 35 38 increase increase VB cord-321499-17n9tj70 35 39 iatrogenic iatrogenic JJ cord-321499-17n9tj70 35 40 risk risk NN cord-321499-17n9tj70 35 41 without without IN cord-321499-17n9tj70 35 42 proportionate proportionate JJ cord-321499-17n9tj70 35 43 benefit benefit NN cord-321499-17n9tj70 35 44 [ [ -LRB- cord-321499-17n9tj70 35 45 13 13 CD cord-321499-17n9tj70 35 46 , , , cord-321499-17n9tj70 35 47 14 14 CD cord-321499-17n9tj70 35 48 ] ] -RRB- cord-321499-17n9tj70 35 49 . . . cord-321499-17n9tj70 36 1 In in IN cord-321499-17n9tj70 36 2 more more JJR cord-321499-17n9tj70 36 3 severe severe JJ cord-321499-17n9tj70 36 4 cases case NNS cord-321499-17n9tj70 36 5 and and CC cord-321499-17n9tj70 36 6 at at IN cord-321499-17n9tj70 36 7 a a DT cord-321499-17n9tj70 36 8 later later JJ cord-321499-17n9tj70 36 9 stage stage NN cord-321499-17n9tj70 36 10 , , , cord-321499-17n9tj70 36 11 however however RB cord-321499-17n9tj70 36 12 , , , cord-321499-17n9tj70 36 13 those those DT cord-321499-17n9tj70 36 14 same same JJ cord-321499-17n9tj70 36 15 actions action NNS cord-321499-17n9tj70 36 16 become become VBP cord-321499-17n9tj70 36 17 quite quite RB cord-321499-17n9tj70 36 18 appropriate appropriate JJ cord-321499-17n9tj70 36 19 . . . cord-321499-17n9tj70 37 1 In in IN cord-321499-17n9tj70 37 2 summary summary NN cord-321499-17n9tj70 37 3 , , , cord-321499-17n9tj70 37 4 it -PRON- PRP cord-321499-17n9tj70 37 5 is be VBZ cord-321499-17n9tj70 37 6 not not RB cord-321499-17n9tj70 37 7 yet yet RB cord-321499-17n9tj70 37 8 known know VBN cord-321499-17n9tj70 37 9 whether whether IN cord-321499-17n9tj70 37 10 standard standard JJ cord-321499-17n9tj70 37 11 evidence evidence NN cord-321499-17n9tj70 37 12 - - HYPH cord-321499-17n9tj70 37 13 based base VBN cord-321499-17n9tj70 37 14 approaches approach NNS cord-321499-17n9tj70 37 15 to to IN cord-321499-17n9tj70 37 16 ARDS ARDS NNP cord-321499-17n9tj70 37 17 management management NN cord-321499-17n9tj70 37 18 apply apply VB cord-321499-17n9tj70 37 19 equally equally RB cord-321499-17n9tj70 37 20 well well RB cord-321499-17n9tj70 37 21 at at IN cord-321499-17n9tj70 37 22 all all DT cord-321499-17n9tj70 37 23 stages stage NNS cord-321499-17n9tj70 37 24 and and CC cord-321499-17n9tj70 37 25 severities severity NNS cord-321499-17n9tj70 37 26 of of IN cord-321499-17n9tj70 37 27 CARDS card NNS cord-321499-17n9tj70 37 28 . . . cord-321499-17n9tj70 38 1 Progress progress VB cord-321499-17n9tj70 38 2 in in IN cord-321499-17n9tj70 38 3 understanding understand VBG cord-321499-17n9tj70 38 4 the the DT cord-321499-17n9tj70 38 5 biological biological JJ cord-321499-17n9tj70 38 6 mechanisms mechanism NNS cord-321499-17n9tj70 38 7 of of IN cord-321499-17n9tj70 38 8 COVID-19 COVID-19 NNP cord-321499-17n9tj70 38 9 has have VBZ cord-321499-17n9tj70 38 10 been be VBN cord-321499-17n9tj70 38 11 quite quite RB cord-321499-17n9tj70 38 12 rapid rapid JJ cord-321499-17n9tj70 38 13 , , , cord-321499-17n9tj70 38 14 but but CC cord-321499-17n9tj70 38 15 there there EX cord-321499-17n9tj70 38 16 remain remain VBP cord-321499-17n9tj70 38 17 many many JJ cord-321499-17n9tj70 38 18 unknowns unknown NNS cord-321499-17n9tj70 38 19 regarding regard VBG cord-321499-17n9tj70 38 20 its -PRON- PRP$ cord-321499-17n9tj70 38 21 expression expression NN cord-321499-17n9tj70 38 22 and and CC cord-321499-17n9tj70 38 23 management management NN cord-321499-17n9tj70 38 24 . . . cord-321499-17n9tj70 39 1 In in IN cord-321499-17n9tj70 39 2 confronting confront VBG cord-321499-17n9tj70 39 3 COVID-19 covid-19 CD cord-321499-17n9tj70 39 4 , , , cord-321499-17n9tj70 39 5 there there EX cord-321499-17n9tj70 39 6 have have VBP cord-321499-17n9tj70 39 7 been be VBN cord-321499-17n9tj70 39 8 shared share VBN cord-321499-17n9tj70 39 9 experiences experience NNS cord-321499-17n9tj70 39 10 and and CC cord-321499-17n9tj70 39 11 points point NNS cord-321499-17n9tj70 39 12 of of IN cord-321499-17n9tj70 39 13 agreement agreement NN cord-321499-17n9tj70 39 14 ( ( -LRB- cord-321499-17n9tj70 39 15 Table Table NNP cord-321499-17n9tj70 39 16 1 1 CD cord-321499-17n9tj70 39 17 ) ) -RRB- cord-321499-17n9tj70 39 18 , , , cord-321499-17n9tj70 39 19 but but CC cord-321499-17n9tj70 39 20 the the DT cord-321499-17n9tj70 39 21 varied varied JJ cord-321499-17n9tj70 39 22 and and CC cord-321499-17n9tj70 39 23 puzzling puzzling JJ cord-321499-17n9tj70 39 24 expressions expression NNS cord-321499-17n9tj70 39 25 of of IN cord-321499-17n9tj70 39 26 COVID-19 COVID-19 , cord-321499-17n9tj70 39 27 have have VBP cord-321499-17n9tj70 39 28 challenged challenge VBN cord-321499-17n9tj70 39 29 the the DT cord-321499-17n9tj70 39 30 uniformity uniformity NN cord-321499-17n9tj70 39 31 of of IN cord-321499-17n9tj70 39 32 our -PRON- PRP$ cord-321499-17n9tj70 39 33 perceptions perception NNS cord-321499-17n9tj70 39 34 and and CC cord-321499-17n9tj70 39 35 in in IN cord-321499-17n9tj70 39 36 some some DT cord-321499-17n9tj70 39 37 cases case NNS cord-321499-17n9tj70 39 38 stimulated stimulate VBD cord-321499-17n9tj70 39 39 brisk brisk JJ cord-321499-17n9tj70 39 40 controversy controversy NN cord-321499-17n9tj70 39 41 [ [ -LRB- cord-321499-17n9tj70 39 42 15 15 CD cord-321499-17n9tj70 39 43 ] ] -RRB- cord-321499-17n9tj70 39 44 [ [ -LRB- cord-321499-17n9tj70 39 45 16 16 CD cord-321499-17n9tj70 39 46 ] ] -RRB- cord-321499-17n9tj70 39 47 [ [ -LRB- cord-321499-17n9tj70 39 48 17 17 CD cord-321499-17n9tj70 39 49 ] ] -RRB- cord-321499-17n9tj70 39 50 [ [ -LRB- cord-321499-17n9tj70 39 51 18 18 CD cord-321499-17n9tj70 39 52 ] ] -RRB- cord-321499-17n9tj70 39 53 . . . cord-321499-17n9tj70 40 1 For for IN cord-321499-17n9tj70 40 2 example example NN cord-321499-17n9tj70 40 3 , , , cord-321499-17n9tj70 40 4 we -PRON- PRP cord-321499-17n9tj70 40 5 argue argue VBP cord-321499-17n9tj70 40 6 : : : cord-321499-17n9tj70 40 7 Does do VBZ cord-321499-17n9tj70 40 8 intense intense JJ cord-321499-17n9tj70 40 9 , , , cord-321499-17n9tj70 40 10 sepsis sepsis NN cord-321499-17n9tj70 40 11 - - HYPH cord-321499-17n9tj70 40 12 like like JJ cord-321499-17n9tj70 40 13 cytokine cytokine NN cord-321499-17n9tj70 40 14 release release NN cord-321499-17n9tj70 40 15 drive drive NN cord-321499-17n9tj70 40 16 shock shock NN cord-321499-17n9tj70 40 17 ? ? . cord-321499-17n9tj70 41 1 [ [ -LRB- cord-321499-17n9tj70 41 2 15 15 CD cord-321499-17n9tj70 41 3 ] ] -RRB- cord-321499-17n9tj70 41 4 . . . cord-321499-17n9tj70 42 1 Should Should MD cord-321499-17n9tj70 42 2 we -PRON- PRP cord-321499-17n9tj70 42 3 manage manage VB cord-321499-17n9tj70 42 4 CARDS CARDS NNP cord-321499-17n9tj70 42 5 as as IN cord-321499-17n9tj70 42 6 routine routine JJ cord-321499-17n9tj70 42 7 ARDS ARDS NNP cord-321499-17n9tj70 42 8 ? ? . cord-321499-17n9tj70 43 1 [ [ -LRB- cord-321499-17n9tj70 43 2 18 18 CD cord-321499-17n9tj70 43 3 ] ] -RRB- cord-321499-17n9tj70 43 4 . . . cord-321499-17n9tj70 44 1 The the DT cord-321499-17n9tj70 44 2 basis basis NN cord-321499-17n9tj70 44 3 of of IN cord-321499-17n9tj70 44 4 such such JJ cord-321499-17n9tj70 44 5 disagreements disagreement NNS cord-321499-17n9tj70 44 6 may may MD cord-321499-17n9tj70 44 7 lie lie VB cord-321499-17n9tj70 44 8 less less RBR cord-321499-17n9tj70 44 9 with with IN cord-321499-17n9tj70 44 10 the the DT cord-321499-17n9tj70 44 11 soundness soundness NN cord-321499-17n9tj70 44 12 of of IN cord-321499-17n9tj70 44 13 the the DT cord-321499-17n9tj70 44 14 observations observation NNS cord-321499-17n9tj70 44 15 among among IN cord-321499-17n9tj70 44 16 reports report NNS cord-321499-17n9tj70 44 17 and and CC cord-321499-17n9tj70 44 18 more more JJR cord-321499-17n9tj70 44 19 with with IN cord-321499-17n9tj70 44 20 patient patient JJ cord-321499-17n9tj70 44 21 vulnerability vulnerability NN cord-321499-17n9tj70 44 22 to to TO cord-321499-17n9tj70 44 23 attack attack VB cord-321499-17n9tj70 44 24 by by IN cord-321499-17n9tj70 44 25 COVID-19 COVID-19 NNP cord-321499-17n9tj70 44 26 and and CC cord-321499-17n9tj70 44 27 its -PRON- PRP$ cord-321499-17n9tj70 44 28 rapidly rapidly RB cord-321499-17n9tj70 44 29 evolving evolve VBG cord-321499-17n9tj70 44 30 pathophysiology pathophysiology NN cord-321499-17n9tj70 44 31 . . . cord-321499-17n9tj70 45 1 The the DT cord-321499-17n9tj70 45 2 validity validity NN cord-321499-17n9tj70 45 3 of of IN cord-321499-17n9tj70 45 4 any any DT cord-321499-17n9tj70 45 5 given give VBN cord-321499-17n9tj70 45 6 observation observation NN cord-321499-17n9tj70 45 7 and and CC cord-321499-17n9tj70 45 8 inference inference NN cord-321499-17n9tj70 45 9 for for IN cord-321499-17n9tj70 45 10 management management NN cord-321499-17n9tj70 45 11 may may MD cord-321499-17n9tj70 45 12 depend depend VB cord-321499-17n9tj70 45 13 strongly strongly RB cord-321499-17n9tj70 45 14 , , , cord-321499-17n9tj70 45 15 for for IN cord-321499-17n9tj70 45 16 instance instance NN cord-321499-17n9tj70 45 17 , , , cord-321499-17n9tj70 45 18 on on IN cord-321499-17n9tj70 45 19 when when WRB cord-321499-17n9tj70 45 20 in in IN cord-321499-17n9tj70 45 21 the the DT cord-321499-17n9tj70 45 22 course course NN cord-321499-17n9tj70 45 23 of of IN cord-321499-17n9tj70 45 24 the the DT cord-321499-17n9tj70 45 25 encounter encounter NN cord-321499-17n9tj70 45 26 the the DT cord-321499-17n9tj70 45 27 observation observation NN cord-321499-17n9tj70 45 28 was be VBD cord-321499-17n9tj70 45 29 made make VBN cord-321499-17n9tj70 46 1 ( ( -LRB- cord-321499-17n9tj70 46 2 Fig Fig NNP cord-321499-17n9tj70 46 3 . . . cord-321499-17n9tj70 47 1 1 1 LS cord-321499-17n9tj70 47 2 ) ) -RRB- cord-321499-17n9tj70 47 3 . . . cord-321499-17n9tj70 48 1 In in IN cord-321499-17n9tj70 48 2 a a DT cord-321499-17n9tj70 48 3 sense sense NN cord-321499-17n9tj70 48 4 , , , cord-321499-17n9tj70 48 5 with with IN cord-321499-17n9tj70 48 6 COVID-19 COVID-19 NNP cord-321499-17n9tj70 48 7 , , , cord-321499-17n9tj70 48 8 we -PRON- PRP cord-321499-17n9tj70 48 9 intensivists intensivist NNS cord-321499-17n9tj70 48 10 are be VBP cord-321499-17n9tj70 48 11 like like IN cord-321499-17n9tj70 48 12 the the DT cord-321499-17n9tj70 48 13 blind blind JJ cord-321499-17n9tj70 48 14 people people NNS cord-321499-17n9tj70 48 15 of of IN cord-321499-17n9tj70 48 16 an an DT cord-321499-17n9tj70 48 17 ancient ancient JJ cord-321499-17n9tj70 48 18 Indian indian JJ cord-321499-17n9tj70 48 19 parable parable NN cord-321499-17n9tj70 48 20 who who WP cord-321499-17n9tj70 48 21 stumble stumble VBP cord-321499-17n9tj70 48 22 upon upon IN cord-321499-17n9tj70 48 23 an an DT cord-321499-17n9tj70 48 24 unfamiliar unfamiliar JJ cord-321499-17n9tj70 48 25 animal animal NN cord-321499-17n9tj70 48 26 , , , cord-321499-17n9tj70 48 27 an an DT cord-321499-17n9tj70 48 28 elephant elephant NN cord-321499-17n9tj70 48 29 . . . cord-321499-17n9tj70 49 1 Each each DT cord-321499-17n9tj70 49 2 individual individual JJ cord-321499-17n9tj70 49 3 forms form VBZ cord-321499-17n9tj70 49 4 a a DT cord-321499-17n9tj70 49 5 different different JJ cord-321499-17n9tj70 49 6 image image NN cord-321499-17n9tj70 49 7 of of IN cord-321499-17n9tj70 49 8 the the DT cord-321499-17n9tj70 49 9 unseen unseen JJ cord-321499-17n9tj70 49 10 beast beast NN cord-321499-17n9tj70 49 11 from from IN cord-321499-17n9tj70 49 12 the the DT cord-321499-17n9tj70 49 13 part part NN cord-321499-17n9tj70 49 14 his -PRON- PRP$ cord-321499-17n9tj70 49 15 or or CC cord-321499-17n9tj70 49 16 her -PRON- PRP$ cord-321499-17n9tj70 49 17 own own JJ cord-321499-17n9tj70 49 18 hands hand NNS cord-321499-17n9tj70 49 19 happen happen VBP cord-321499-17n9tj70 49 20 to to TO cord-321499-17n9tj70 49 21 fall fall VB cord-321499-17n9tj70 49 22 upon upon IN cord-321499-17n9tj70 50 1 that that DT cord-321499-17n9tj70 50 2 resembles resemble VBZ cord-321499-17n9tj70 50 3 the the DT cord-321499-17n9tj70 50 4 familiar familiar JJ cord-321499-17n9tj70 50 5 . . . cord-321499-17n9tj70 51 1 The the DT cord-321499-17n9tj70 51 2 individual individual JJ cord-321499-17n9tj70 51 3 tactile tactile JJ cord-321499-17n9tj70 51 4 sensations sensation NNS cord-321499-17n9tj70 51 5 are be VBP cord-321499-17n9tj70 51 6 undeniable undeniable JJ cord-321499-17n9tj70 51 7 , , , cord-321499-17n9tj70 51 8 and and CC cord-321499-17n9tj70 51 9 each each DT cord-321499-17n9tj70 51 10 interpretation interpretation NN cord-321499-17n9tj70 51 11 and and CC cord-321499-17n9tj70 51 12 extrapolation extrapolation NN cord-321499-17n9tj70 51 13 to to TO cord-321499-17n9tj70 51 14 characterize characterize VB cord-321499-17n9tj70 51 15 the the DT cord-321499-17n9tj70 51 16 elephant elephant NN cord-321499-17n9tj70 51 17 is be VBZ cord-321499-17n9tj70 51 18 understandable understandable JJ cord-321499-17n9tj70 51 19 - - : cord-321499-17n9tj70 51 20 but but CC cord-321499-17n9tj70 51 21 ultimately ultimately RB cord-321499-17n9tj70 51 22 , , , cord-321499-17n9tj70 51 23 incomplete incomplete JJ cord-321499-17n9tj70 51 24 . . . cord-321499-17n9tj70 51 25 _SP cord-321499-17n9tj70 52 1 Puzzling puzzle VBG cord-321499-17n9tj70 52 2 or or CC cord-321499-17n9tj70 52 3 contested contest VBN cord-321499-17n9tj70 52 4 features feature VBZ cord-321499-17n9tj70 52 5 a a DT cord-321499-17n9tj70 53 1 The the DT cord-321499-17n9tj70 53 2 virus virus NN cord-321499-17n9tj70 53 3 is be VBZ cord-321499-17n9tj70 53 4 easily easily RB cord-321499-17n9tj70 53 5 spread spread VBN cord-321499-17n9tj70 53 6 and and CC cord-321499-17n9tj70 53 7 by by IN cord-321499-17n9tj70 53 8 multiple multiple JJ cord-321499-17n9tj70 53 9 routes route NNS cord-321499-17n9tj70 53 10 ( ( -LRB- cord-321499-17n9tj70 53 11 droplet droplet NN cord-321499-17n9tj70 53 12 , , , cord-321499-17n9tj70 53 13 aerosol aerosol NN cord-321499-17n9tj70 53 14 , , , cord-321499-17n9tj70 53 15 contact contact NN cord-321499-17n9tj70 53 16 ) ) -RRB- cord-321499-17n9tj70 54 1 What what WP cord-321499-17n9tj70 54 2 explains explain VBZ cord-321499-17n9tj70 54 3 striking strike VBG cord-321499-17n9tj70 54 4 geographic geographic JJ cord-321499-17n9tj70 54 5 differences difference NNS cord-321499-17n9tj70 54 6 of of IN cord-321499-17n9tj70 54 7 incidence incidence NN cord-321499-17n9tj70 54 8 ? ? . cord-321499-17n9tj70 55 1 Many many JJ cord-321499-17n9tj70 55 2 infected infected JJ cord-321499-17n9tj70 55 3 persons person NNS cord-321499-17n9tj70 55 4 are be VBP cord-321499-17n9tj70 55 5 asymptomatic asymptomatic JJ cord-321499-17n9tj70 55 6 , , , cord-321499-17n9tj70 55 7 a a DT cord-321499-17n9tj70 55 8 smaller small JJR cord-321499-17n9tj70 55 9 number number NN cord-321499-17n9tj70 55 10 require require VBP cord-321499-17n9tj70 55 11 hospitalization hospitalization NN cord-321499-17n9tj70 55 12 , , , cord-321499-17n9tj70 55 13 and and CC cord-321499-17n9tj70 55 14 even even RB cord-321499-17n9tj70 55 15 fewer few JJR cord-321499-17n9tj70 55 16 develop develop VB cord-321499-17n9tj70 55 17 respiratory respiratory JJ cord-321499-17n9tj70 55 18 failure failure NN cord-321499-17n9tj70 56 1 What what WP cord-321499-17n9tj70 56 2 explains explain VBZ cord-321499-17n9tj70 56 3 highly highly RB cord-321499-17n9tj70 56 4 variable variable JJ cord-321499-17n9tj70 56 5 mortality mortality NN cord-321499-17n9tj70 56 6 rates rate NNS cord-321499-17n9tj70 56 7 , , , cord-321499-17n9tj70 56 8 site site NN cord-321499-17n9tj70 56 9 - - HYPH cord-321499-17n9tj70 56 10 to to IN cord-321499-17n9tj70 56 11 - - HYPH cord-321499-17n9tj70 56 12 site site NN cord-321499-17n9tj70 56 13 ? ? . cord-321499-17n9tj70 57 1 Children child NNS cord-321499-17n9tj70 57 2 are be VBP cord-321499-17n9tj70 57 3 affected affect VBN cord-321499-17n9tj70 57 4 less less RBR cord-321499-17n9tj70 57 5 often often RB cord-321499-17n9tj70 57 6 and and CC cord-321499-17n9tj70 57 7 usually usually RB cord-321499-17n9tj70 57 8 less less RBR cord-321499-17n9tj70 57 9 severely severely RB cord-321499-17n9tj70 57 10 than than IN cord-321499-17n9tj70 57 11 adults adult NNS cord-321499-17n9tj70 57 12 , , , cord-321499-17n9tj70 57 13 yet yet CC cord-321499-17n9tj70 57 14 may may MD cord-321499-17n9tj70 57 15 have have VB cord-321499-17n9tj70 57 16 rare rare JJ cord-321499-17n9tj70 57 17 post post JJ cord-321499-17n9tj70 57 18 - - JJ cord-321499-17n9tj70 57 19 infectious infectious JJ cord-321499-17n9tj70 57 20 complications complication NNS cord-321499-17n9tj70 57 21 related relate VBN cord-321499-17n9tj70 57 22 to to IN cord-321499-17n9tj70 57 23 previous previous JJ cord-321499-17n9tj70 57 24 vascular vascular JJ cord-321499-17n9tj70 57 25 invasion invasion NN cord-321499-17n9tj70 57 26 Are be VBP cord-321499-17n9tj70 57 27 there there EX cord-321499-17n9tj70 57 28 different different JJ cord-321499-17n9tj70 57 29 COVID-19 covid-19 JJ cord-321499-17n9tj70 57 30 genetic genetic JJ cord-321499-17n9tj70 57 31 types type NNS cord-321499-17n9tj70 57 32 and and CC cord-321499-17n9tj70 57 33 virulence virulence NN cord-321499-17n9tj70 57 34 , , , cord-321499-17n9tj70 57 35 perhaps perhaps RB cord-321499-17n9tj70 57 36 due due IN cord-321499-17n9tj70 57 37 to to IN cord-321499-17n9tj70 57 38 its -PRON- PRP$ cord-321499-17n9tj70 57 39 RNA RNA NNP cord-321499-17n9tj70 57 40 mutations mutation NNS cord-321499-17n9tj70 57 41 ? ? . cord-321499-17n9tj70 58 1 Mortality mortality NN cord-321499-17n9tj70 58 2 rates rate NNS cord-321499-17n9tj70 58 3 are be VBP cord-321499-17n9tj70 58 4 higher high JJR cord-321499-17n9tj70 58 5 among among IN cord-321499-17n9tj70 58 6 those those DT cord-321499-17n9tj70 58 7 with with IN cord-321499-17n9tj70 58 8 diabetes diabetes NN cord-321499-17n9tj70 58 9 , , , cord-321499-17n9tj70 58 10 hypertension hypertension NN cord-321499-17n9tj70 58 11 , , , cord-321499-17n9tj70 58 12 chronic chronic JJ cord-321499-17n9tj70 58 13 heart heart NN cord-321499-17n9tj70 58 14 or or CC cord-321499-17n9tj70 58 15 lung lung NN cord-321499-17n9tj70 58 16 disease disease NN cord-321499-17n9tj70 58 17 , , , cord-321499-17n9tj70 58 18 the the DT cord-321499-17n9tj70 58 19 elderly elderly JJ cord-321499-17n9tj70 58 20 , , , cord-321499-17n9tj70 58 21 and and CC cord-321499-17n9tj70 58 22 the the DT cord-321499-17n9tj70 58 23 morbidly morbidly RB cord-321499-17n9tj70 58 24 obese obese JJ cord-321499-17n9tj70 59 1 Can Can MD cord-321499-17n9tj70 59 2 we -PRON- PRP cord-321499-17n9tj70 59 3 develop develop VB cord-321499-17n9tj70 59 4 an an DT cord-321499-17n9tj70 59 5 effective effective JJ cord-321499-17n9tj70 59 6 vaccine vaccine NN cord-321499-17n9tj70 59 7 against against IN cord-321499-17n9tj70 59 8 variants variant NNS cord-321499-17n9tj70 59 9 of of IN cord-321499-17n9tj70 59 10 COVID COVID NNP cord-321499-17n9tj70 59 11 and and CC cord-321499-17n9tj70 59 12 distribute distribute VB cord-321499-17n9tj70 59 13 it -PRON- PRP cord-321499-17n9tj70 59 14 worldwide worldwide RB cord-321499-17n9tj70 59 15 ? ? . cord-321499-17n9tj70 60 1 How how WRB cord-321499-17n9tj70 60 2 long long RB cord-321499-17n9tj70 60 3 will will MD cord-321499-17n9tj70 60 4 such such PDT cord-321499-17n9tj70 60 5 a a DT cord-321499-17n9tj70 60 6 vaccine vaccine NN cord-321499-17n9tj70 60 7 be be VB cord-321499-17n9tj70 60 8 effective effective JJ cord-321499-17n9tj70 60 9 ? ? . cord-321499-17n9tj70 61 1 So so RB cord-321499-17n9tj70 61 2 - - HYPH cord-321499-17n9tj70 61 3 called call VBN cord-321499-17n9tj70 61 4 ' ' `` cord-321499-17n9tj70 61 5 silent silent JJ cord-321499-17n9tj70 61 6 hypoxemia hypoxemia NN cord-321499-17n9tj70 61 7 ' ' '' cord-321499-17n9tj70 61 8 may may MD cord-321499-17n9tj70 61 9 precede precede VB cord-321499-17n9tj70 61 10 overt overt JJ cord-321499-17n9tj70 61 11 respiratory respiratory JJ cord-321499-17n9tj70 61 12 distress distress NN cord-321499-17n9tj70 61 13 Are be VBP cord-321499-17n9tj70 61 14 there there EX cord-321499-17n9tj70 61 15 inflammatory inflammatory JJ cord-321499-17n9tj70 61 16 versus versus IN cord-321499-17n9tj70 61 17 non non JJ cord-321499-17n9tj70 61 18 - - JJ cord-321499-17n9tj70 61 19 inflammatory inflammatory JJ cord-321499-17n9tj70 61 20 phenotypes phenotype NNS cord-321499-17n9tj70 61 21 of of IN cord-321499-17n9tj70 61 22 CARDS card NNS cord-321499-17n9tj70 61 23 ? ? . cord-321499-17n9tj70 62 1 Unusually unusually RB cord-321499-17n9tj70 62 2 high high JJ cord-321499-17n9tj70 62 3 minute minute NN cord-321499-17n9tj70 62 4 ventilation ventilation NN cord-321499-17n9tj70 62 5 and and CC cord-321499-17n9tj70 62 6 high high JJ cord-321499-17n9tj70 62 7 dead dead JJ cord-321499-17n9tj70 62 8 space space NN cord-321499-17n9tj70 62 9 may may MD cord-321499-17n9tj70 62 10 be be VB cord-321499-17n9tj70 62 11 evident evident JJ cord-321499-17n9tj70 62 12 from from IN cord-321499-17n9tj70 62 13 the the DT cord-321499-17n9tj70 62 14 outset outset NN cord-321499-17n9tj70 62 15 What what WDT cord-321499-17n9tj70 62 16 role role NN cord-321499-17n9tj70 62 17 does do VBZ cord-321499-17n9tj70 62 18 ' ' `` cord-321499-17n9tj70 62 19 cytokine cytokine NN cord-321499-17n9tj70 62 20 storm storm NN cord-321499-17n9tj70 62 21 ' ' '' cord-321499-17n9tj70 62 22 play play NN cord-321499-17n9tj70 62 23 in in IN cord-321499-17n9tj70 62 24 the the DT cord-321499-17n9tj70 62 25 clinical clinical JJ cord-321499-17n9tj70 62 26 presentations presentation NNS cord-321499-17n9tj70 62 27 of of IN cord-321499-17n9tj70 62 28 COVID-19 COVID-19 NNP cord-321499-17n9tj70 62 29 ? ? . cord-321499-17n9tj70 63 1 Abrupt abrupt JJ cord-321499-17n9tj70 63 2 deterioration deterioration NN cord-321499-17n9tj70 63 3 often often RB cord-321499-17n9tj70 63 4 occurs occur VBZ cord-321499-17n9tj70 63 5 after after IN cord-321499-17n9tj70 63 6 days day NNS cord-321499-17n9tj70 63 7 of of IN cord-321499-17n9tj70 63 8 smoldering smolder VBG cord-321499-17n9tj70 63 9 infection infection NN cord-321499-17n9tj70 63 10 Do do VBP cord-321499-17n9tj70 63 11 symptomatic symptomatic JJ cord-321499-17n9tj70 63 12 patients patient NNS cord-321499-17n9tj70 63 13 who who WP cord-321499-17n9tj70 63 14 present present VBP cord-321499-17n9tj70 63 15 with with IN cord-321499-17n9tj70 63 16 severe severe JJ cord-321499-17n9tj70 63 17 hypoxemia hypoxemia NN cord-321499-17n9tj70 63 18 sort sort NN cord-321499-17n9tj70 63 19 into into IN cord-321499-17n9tj70 63 20 " " `` cord-321499-17n9tj70 63 21 L l NN cord-321499-17n9tj70 63 22 and and CC cord-321499-17n9tj70 63 23 H H NNP cord-321499-17n9tj70 63 24 " " '' cord-321499-17n9tj70 63 25 phenotypes phenotype NNS cord-321499-17n9tj70 63 26 ? ? . cord-321499-17n9tj70 64 1 Respiratory respiratory JJ cord-321499-17n9tj70 64 2 system system NN cord-321499-17n9tj70 64 3 compliance compliance NN cord-321499-17n9tj70 64 4 is be VBZ cord-321499-17n9tj70 64 5 not not RB cord-321499-17n9tj70 64 6 invariably invariably RB cord-321499-17n9tj70 64 7 low low JJ cord-321499-17n9tj70 64 8 in in IN cord-321499-17n9tj70 64 9 the the DT cord-321499-17n9tj70 64 10 presence presence NN cord-321499-17n9tj70 64 11 of of IN cord-321499-17n9tj70 64 12 severe severe JJ cord-321499-17n9tj70 64 13 hypoxemia hypoxemia NN cord-321499-17n9tj70 65 1 Do do VBP cord-321499-17n9tj70 65 2 patients patient NNS cord-321499-17n9tj70 65 3 progress progress VB cord-321499-17n9tj70 65 4 to to TO cord-321499-17n9tj70 65 5 diffuse diffuse VB cord-321499-17n9tj70 65 6 airspace airspace NN cord-321499-17n9tj70 65 7 disease disease NN cord-321499-17n9tj70 65 8 via via IN cord-321499-17n9tj70 65 9 patient patient JJ cord-321499-17n9tj70 65 10 self self NN cord-321499-17n9tj70 65 11 - - HYPH cord-321499-17n9tj70 65 12 inflicted inflict VBN cord-321499-17n9tj70 65 13 lung lung NN cord-321499-17n9tj70 65 14 injury injury NN cord-321499-17n9tj70 65 15 ( ( -LRB- cord-321499-17n9tj70 65 16 PSILI PSILI NNP cord-321499-17n9tj70 65 17 ) ) -RRB- cord-321499-17n9tj70 65 18 ? ? . cord-321499-17n9tj70 66 1 Incidence incidence NN cord-321499-17n9tj70 66 2 of of IN cord-321499-17n9tj70 66 3 blood blood NN cord-321499-17n9tj70 66 4 clotting clotting NN cord-321499-17n9tj70 66 5 appears appear VBZ cord-321499-17n9tj70 66 6 to to TO cord-321499-17n9tj70 66 7 be be VB cord-321499-17n9tj70 66 8 high high JJ cord-321499-17n9tj70 66 9 in in IN cord-321499-17n9tj70 66 10 hospitalized hospitalize VBN cord-321499-17n9tj70 66 11 COVID-19 covid-19 CD cord-321499-17n9tj70 66 12 patients patient NNS cord-321499-17n9tj70 67 1 Does do VBZ cord-321499-17n9tj70 67 2 the the DT cord-321499-17n9tj70 67 3 fact fact NN cord-321499-17n9tj70 67 4 that that IN cord-321499-17n9tj70 67 5 CARDS card NNS cord-321499-17n9tj70 67 6 patients patient NNS cord-321499-17n9tj70 67 7 meet meet VBP cord-321499-17n9tj70 67 8 the the DT cord-321499-17n9tj70 67 9 Berlin Berlin NNP cord-321499-17n9tj70 67 10 definition definition NN cord-321499-17n9tj70 67 11 mean mean VB cord-321499-17n9tj70 67 12 that that IN cord-321499-17n9tj70 67 13 these these DT cord-321499-17n9tj70 67 14 patients patient NNS cord-321499-17n9tj70 67 15 will will MD cord-321499-17n9tj70 67 16 respond respond VB cord-321499-17n9tj70 67 17 to to IN cord-321499-17n9tj70 67 18 standard standard JJ cord-321499-17n9tj70 67 19 approaches approach NNS cord-321499-17n9tj70 67 20 and and CC cord-321499-17n9tj70 67 21 guidelines guideline NNS cord-321499-17n9tj70 67 22 for for IN cord-321499-17n9tj70 67 23 ARDS ARDS NNP cord-321499-17n9tj70 67 24 ? ? . cord-321499-17n9tj70 68 1 Early early JJ cord-321499-17n9tj70 68 2 CT CT NNP cord-321499-17n9tj70 68 3 infiltrates infiltrate VBZ cord-321499-17n9tj70 68 4 occurring occur VBG cord-321499-17n9tj70 68 5 in in IN cord-321499-17n9tj70 68 6 severely severely RB cord-321499-17n9tj70 68 7 hypoxemic hypoxemic JJ cord-321499-17n9tj70 68 8 patients patient NNS cord-321499-17n9tj70 68 9 are be VBP cord-321499-17n9tj70 68 10 often often RB cord-321499-17n9tj70 68 11 scant scant JJ cord-321499-17n9tj70 68 12 , , , cord-321499-17n9tj70 68 13 peripheral peripheral JJ cord-321499-17n9tj70 68 14 , , , cord-321499-17n9tj70 68 15 and and CC cord-321499-17n9tj70 68 16 characterized characterize VBN cord-321499-17n9tj70 68 17 by by IN cord-321499-17n9tj70 68 18 atypical atypical JJ cord-321499-17n9tj70 68 19 ' ' `` cord-321499-17n9tj70 68 20 ground ground NN cord-321499-17n9tj70 68 21 glass glass NN cord-321499-17n9tj70 68 22 ' ' '' cord-321499-17n9tj70 68 23 or or CC cord-321499-17n9tj70 68 24 ' ' `` cord-321499-17n9tj70 68 25 crazy crazy JJ cord-321499-17n9tj70 68 26 paving paving NN cord-321499-17n9tj70 68 27 ' ' '' cord-321499-17n9tj70 68 28 Does do VBZ cord-321499-17n9tj70 68 29 disrupted disrupt VBN cord-321499-17n9tj70 68 30 vasoregulation vasoregulation NN cord-321499-17n9tj70 68 31 with with IN cord-321499-17n9tj70 68 32 minor minor JJ cord-321499-17n9tj70 68 33 shunt shunt NN cord-321499-17n9tj70 68 34 explain explain VBP cord-321499-17n9tj70 68 35 the the DT cord-321499-17n9tj70 68 36 severity severity NN cord-321499-17n9tj70 68 37 of of IN cord-321499-17n9tj70 68 38 early early JJ cord-321499-17n9tj70 68 39 hypoxemia hypoxemia NN cord-321499-17n9tj70 68 40 ? ? . cord-321499-17n9tj70 69 1 Prone prone JJ cord-321499-17n9tj70 69 2 positioning positioning NN cord-321499-17n9tj70 69 3 and and CC cord-321499-17n9tj70 69 4 PEEP peep NN cord-321499-17n9tj70 69 5 improve improve VB cord-321499-17n9tj70 69 6 PaO pao NN cord-321499-17n9tj70 69 7 2 2 CD cord-321499-17n9tj70 69 8 /FiO /fio SYM cord-321499-17n9tj70 69 9 2 2 CD cord-321499-17n9tj70 69 10 Should Should MD cord-321499-17n9tj70 69 11 full full JJ cord-321499-17n9tj70 69 12 anticoagulation anticoagulation NN cord-321499-17n9tj70 69 13 be be VB cord-321499-17n9tj70 69 14 routinely routinely RB cord-321499-17n9tj70 69 15 implemented implement VBN cord-321499-17n9tj70 69 16 ? ? . cord-321499-17n9tj70 70 1 Respiratory respiratory JJ cord-321499-17n9tj70 70 2 failure failure NN cord-321499-17n9tj70 70 3 often often RB cord-321499-17n9tj70 70 4 resolves resolve VBZ cord-321499-17n9tj70 70 5 slowly slowly RB cord-321499-17n9tj70 70 6 in in IN cord-321499-17n9tj70 70 7 the the DT cord-321499-17n9tj70 70 8 most most RBS cord-321499-17n9tj70 70 9 severely severely RB cord-321499-17n9tj70 70 10 ill ill RB cord-321499-17n9tj70 70 11 who who WP cord-321499-17n9tj70 70 12 do do VBP cord-321499-17n9tj70 70 13 survive survive VB cord-321499-17n9tj70 70 14 Which which WDT cord-321499-17n9tj70 70 15 available available JJ cord-321499-17n9tj70 70 16 drugs drug NNS cord-321499-17n9tj70 70 17 and and CC cord-321499-17n9tj70 70 18 proposed propose VBN cord-321499-17n9tj70 70 19 anti anti JJ cord-321499-17n9tj70 70 20 - - JJ cord-321499-17n9tj70 70 21 viral viral JJ cord-321499-17n9tj70 70 22 approaches approach NNS cord-321499-17n9tj70 70 23 for for IN cord-321499-17n9tj70 70 24 COVID-19 COVID-19 NNP cord-321499-17n9tj70 70 25 treatment treatment NN cord-321499-17n9tj70 70 26 hold hold VBP cord-321499-17n9tj70 70 27 the the DT cord-321499-17n9tj70 70 28 most most RBS cord-321499-17n9tj70 70 29 potential potential NN cord-321499-17n9tj70 70 30 for for IN cord-321499-17n9tj70 70 31 benefit benefit NN cord-321499-17n9tj70 70 32 or or CC cord-321499-17n9tj70 70 33 risk risk NN cord-321499-17n9tj70 70 34 ? ? . cord-321499-17n9tj70 71 1 So so RB cord-321499-17n9tj70 71 2 it -PRON- PRP cord-321499-17n9tj70 71 3 may may MD cord-321499-17n9tj70 71 4 be be VB cord-321499-17n9tj70 71 5 with with IN cord-321499-17n9tj70 71 6 COVID-19 COVID-19 NNP cord-321499-17n9tj70 71 7 . . . cord-321499-17n9tj70 72 1 Well well RB cord-321499-17n9tj70 72 2 - - HYPH cord-321499-17n9tj70 72 3 meaning mean VBG cord-321499-17n9tj70 72 4 authors author NNS cord-321499-17n9tj70 72 5 may may MD cord-321499-17n9tj70 72 6 advocate advocate VB cord-321499-17n9tj70 72 7 for for IN cord-321499-17n9tj70 72 8 individual individual JJ cord-321499-17n9tj70 72 9 interpretations interpretation NNS cord-321499-17n9tj70 72 10 , , , cord-321499-17n9tj70 72 11 but but CC cord-321499-17n9tj70 72 12 our -PRON- PRP$ cord-321499-17n9tj70 72 13 current current JJ cord-321499-17n9tj70 72 14 views view NNS cord-321499-17n9tj70 72 15 of of IN cord-321499-17n9tj70 72 16 the the DT cord-321499-17n9tj70 72 17 entire entire JJ cord-321499-17n9tj70 72 18 problem problem NN cord-321499-17n9tj70 72 19 are be VBP cord-321499-17n9tj70 72 20 obscured obscure VBN cord-321499-17n9tj70 72 21 and and CC cord-321499-17n9tj70 72 22 our -PRON- PRP$ cord-321499-17n9tj70 72 23 answers answer NNS cord-321499-17n9tj70 72 24 half half RB cord-321499-17n9tj70 72 25 - - HYPH cord-321499-17n9tj70 72 26 finished finished JJ cord-321499-17n9tj70 72 27 . . . cord-321499-17n9tj70 73 1 Although although IN cord-321499-17n9tj70 73 2 pathogenesis pathogenesis NN cord-321499-17n9tj70 73 3 is be VBZ cord-321499-17n9tj70 73 4 becoming become VBG cord-321499-17n9tj70 73 5 progressively progressively RB cord-321499-17n9tj70 73 6 clear clear JJ cord-321499-17n9tj70 73 7 and and CC cord-321499-17n9tj70 73 8 many many JJ cord-321499-17n9tj70 73 9 clinical clinical JJ cord-321499-17n9tj70 73 10 trials trial NNS cord-321499-17n9tj70 73 11 of of IN cord-321499-17n9tj70 73 12 promising promising JJ cord-321499-17n9tj70 73 13 treatments treatment NNS cord-321499-17n9tj70 73 14 and and CC cord-321499-17n9tj70 73 15 vaccines vaccine NNS cord-321499-17n9tj70 73 16 have have VBP cord-321499-17n9tj70 73 17 been be VBN cord-321499-17n9tj70 73 18 initiated initiate VBN cord-321499-17n9tj70 73 19 , , , cord-321499-17n9tj70 73 20 we -PRON- PRP cord-321499-17n9tj70 73 21 are be VBP cord-321499-17n9tj70 73 22 still still RB cord-321499-17n9tj70 73 23 at at IN cord-321499-17n9tj70 73 24 the the DT cord-321499-17n9tj70 73 25 stage stage NN cord-321499-17n9tj70 73 26 of of IN cord-321499-17n9tj70 73 27 gathering gather VBG cord-321499-17n9tj70 73 28 fundamental fundamental JJ cord-321499-17n9tj70 73 29 observations observation NNS cord-321499-17n9tj70 73 30 from from IN cord-321499-17n9tj70 73 31 which which WDT cord-321499-17n9tj70 73 32 a a DT cord-321499-17n9tj70 73 33 unified unified JJ cord-321499-17n9tj70 73 34 theory theory NN cord-321499-17n9tj70 73 35 of of IN cord-321499-17n9tj70 73 36 pathogenesis pathogenesis NN cord-321499-17n9tj70 73 37 might may MD cord-321499-17n9tj70 73 38 be be VB cord-321499-17n9tj70 73 39 constructed construct VBN cord-321499-17n9tj70 73 40 , , , cord-321499-17n9tj70 73 41 and and CC cord-321499-17n9tj70 73 42 around around IN cord-321499-17n9tj70 73 43 which which WDT cord-321499-17n9tj70 73 44 logical logical JJ cord-321499-17n9tj70 73 45 and and CC cord-321499-17n9tj70 73 46 effective effective JJ cord-321499-17n9tj70 73 47 treatment treatment NN cord-321499-17n9tj70 73 48 approaches approach NNS cord-321499-17n9tj70 73 49 might may MD cord-321499-17n9tj70 73 50 coalesce coalesce VB cord-321499-17n9tj70 73 51 . . . cord-321499-17n9tj70 74 1 The the DT cord-321499-17n9tj70 74 2 scientific scientific JJ cord-321499-17n9tj70 74 3 process process NN cord-321499-17n9tj70 74 4 is be VBZ cord-321499-17n9tj70 74 5 self self NN cord-321499-17n9tj70 74 6 - - HYPH cord-321499-17n9tj70 74 7 correcting correct VBG cord-321499-17n9tj70 74 8 ; ; : cord-321499-17n9tj70 74 9 over over IN cord-321499-17n9tj70 74 10 time time NN cord-321499-17n9tj70 74 11 , , , cord-321499-17n9tj70 74 12 varied varied JJ cord-321499-17n9tj70 74 13 high high JJ cord-321499-17n9tj70 74 14 - - HYPH cord-321499-17n9tj70 74 15 quality quality NN cord-321499-17n9tj70 74 16 scientific scientific JJ cord-321499-17n9tj70 74 17 and and CC cord-321499-17n9tj70 74 18 clinical clinical JJ cord-321499-17n9tj70 74 19 observations observation NNS cord-321499-17n9tj70 74 20 will will MD cord-321499-17n9tj70 74 21 eventually eventually RB cord-321499-17n9tj70 74 22 be be VB cord-321499-17n9tj70 74 23 drawn draw VBN cord-321499-17n9tj70 74 24 together together RB cord-321499-17n9tj70 74 25 into into IN cord-321499-17n9tj70 74 26 a a DT cord-321499-17n9tj70 74 27 coherent coherent JJ cord-321499-17n9tj70 74 28 , , , cord-321499-17n9tj70 74 29 unified unified JJ cord-321499-17n9tj70 74 30 entity entity NN cord-321499-17n9tj70 74 31 . . . cord-321499-17n9tj70 75 1 Although although IN cord-321499-17n9tj70 75 2 urgency urgency NN cord-321499-17n9tj70 75 3 demands demand VBZ cord-321499-17n9tj70 75 4 that that IN cord-321499-17n9tj70 75 5 we -PRON- PRP cord-321499-17n9tj70 75 6 test test VBP cord-321499-17n9tj70 75 7 especially especially RB cord-321499-17n9tj70 75 8 promising promising JJ cord-321499-17n9tj70 75 9 and and CC cord-321499-17n9tj70 75 10 logical logical JJ cord-321499-17n9tj70 75 11 treatment treatment NN cord-321499-17n9tj70 75 12 options option NNS cord-321499-17n9tj70 75 13 , , , cord-321499-17n9tj70 75 14 for for IN cord-321499-17n9tj70 75 15 the the DT cord-321499-17n9tj70 75 16 present present JJ cord-321499-17n9tj70 75 17 time time NN cord-321499-17n9tj70 75 18 , , , cord-321499-17n9tj70 75 19 it -PRON- PRP cord-321499-17n9tj70 75 20 seems seem VBZ cord-321499-17n9tj70 75 21 prudent prudent JJ cord-321499-17n9tj70 75 22 for for IN cord-321499-17n9tj70 75 23 the the DT cord-321499-17n9tj70 75 24 medical medical JJ cord-321499-17n9tj70 75 25 community community NN cord-321499-17n9tj70 75 26 to to TO cord-321499-17n9tj70 75 27 collate collate VB cord-321499-17n9tj70 75 28 valid valid JJ cord-321499-17n9tj70 75 29 observations observation NNS cord-321499-17n9tj70 75 30 and and CC cord-321499-17n9tj70 75 31 experiences experience NNS cord-321499-17n9tj70 75 32 from from IN cord-321499-17n9tj70 75 33 all all DT cord-321499-17n9tj70 75 34 quarters quarter NNS cord-321499-17n9tj70 75 35 , , , cord-321499-17n9tj70 75 36 form form VB cord-321499-17n9tj70 75 37 the the DT cord-321499-17n9tj70 75 38 right right JJ cord-321499-17n9tj70 75 39 image image NN cord-321499-17n9tj70 75 40 of of IN cord-321499-17n9tj70 75 41 a a DT cord-321499-17n9tj70 75 42 dynamic dynamic JJ cord-321499-17n9tj70 75 43 entity entity NN cord-321499-17n9tj70 75 44 , , , cord-321499-17n9tj70 75 45 and and CC cord-321499-17n9tj70 75 46 then then RB cord-321499-17n9tj70 75 47 devise devise VB cord-321499-17n9tj70 75 48 an an DT cord-321499-17n9tj70 75 49 appropriate appropriate JJ cord-321499-17n9tj70 75 50 strategy strategy NN cord-321499-17n9tj70 75 51 to to TO cord-321499-17n9tj70 75 52 modify modify VB cord-321499-17n9tj70 75 53 supportive supportive JJ cord-321499-17n9tj70 75 54 care care NN cord-321499-17n9tj70 75 55 as as IN cord-321499-17n9tj70 75 56 we -PRON- PRP cord-321499-17n9tj70 75 57 proceed proceed VBP cord-321499-17n9tj70 75 58 to to TO cord-321499-17n9tj70 75 59 develop develop VB cord-321499-17n9tj70 75 60 effective effective JJ cord-321499-17n9tj70 75 61 countermeasures countermeasure NNS cord-321499-17n9tj70 75 62 . . . cord-321499-17n9tj70 76 1 As as IN cord-321499-17n9tj70 76 2 the the DT cord-321499-17n9tj70 76 3 Rajah Rajah NNP cord-321499-17n9tj70 76 4 said say VBD cord-321499-17n9tj70 76 5 to to IN cord-321499-17n9tj70 76 6 the the DT cord-321499-17n9tj70 76 7 bickering bicker VBG cord-321499-17n9tj70 76 8 blind blind JJ cord-321499-17n9tj70 76 9 men man NNS cord-321499-17n9tj70 76 10 when when WRB cord-321499-17n9tj70 76 11 advising advise VBG cord-321499-17n9tj70 76 12 them -PRON- PRP cord-321499-17n9tj70 76 13 to to TO cord-321499-17n9tj70 76 14 humbly humbly RB cord-321499-17n9tj70 76 15 reflect reflect VB cord-321499-17n9tj70 76 16 before before IN cord-321499-17n9tj70 76 17 drawing draw VBG cord-321499-17n9tj70 76 18 conclusions conclusion NNS cord-321499-17n9tj70 76 19 : : : cord-321499-17n9tj70 76 20 " " `` cord-321499-17n9tj70 76 21 The the DT cord-321499-17n9tj70 76 22 elephant elephant NN cord-321499-17n9tj70 76 23 is be VBZ cord-321499-17n9tj70 76 24 a a DT cord-321499-17n9tj70 76 25 very very RB cord-321499-17n9tj70 76 26 large large JJ cord-321499-17n9tj70 76 27 and and CC cord-321499-17n9tj70 76 28 rather rather RB cord-321499-17n9tj70 76 29 strange strange JJ cord-321499-17n9tj70 76 30 animal animal NN cord-321499-17n9tj70 76 31 . . . cord-321499-17n9tj70 77 1 Each each DT cord-321499-17n9tj70 77 2 man man NN cord-321499-17n9tj70 77 3 touched touch VBD cord-321499-17n9tj70 77 4 only only RB cord-321499-17n9tj70 77 5 one one CD cord-321499-17n9tj70 77 6 part part NN cord-321499-17n9tj70 77 7 . . . cord-321499-17n9tj70 78 1 Perhaps perhaps RB cord-321499-17n9tj70 78 2 if if IN cord-321499-17n9tj70 78 3 you -PRON- PRP cord-321499-17n9tj70 78 4 put put VBP cord-321499-17n9tj70 78 5 the the DT cord-321499-17n9tj70 78 6 parts part NNS cord-321499-17n9tj70 78 7 together together RB cord-321499-17n9tj70 78 8 , , , cord-321499-17n9tj70 78 9 you -PRON- PRP cord-321499-17n9tj70 78 10 will will MD cord-321499-17n9tj70 78 11 eventually eventually RB cord-321499-17n9tj70 78 12 see see VB cord-321499-17n9tj70 78 13 the the DT cord-321499-17n9tj70 78 14 truth truth NN cord-321499-17n9tj70 78 15 . . . cord-321499-17n9tj70 78 16 " " '' cord-321499-17n9tj70 78 17 _SP cord-321499-17n9tj70 79 1 SARS SARS NNP cord-321499-17n9tj70 79 2 - - HYPH cord-321499-17n9tj70 79 3 CoV-2 CoV-2 NNP cord-321499-17n9tj70 79 4 : : : cord-321499-17n9tj70 79 5 first first RB cord-321499-17n9tj70 79 6 do do VB cord-321499-17n9tj70 79 7 no no DT cord-321499-17n9tj70 79 8 harm harm NN cord-321499-17n9tj70 79 9 Learning learn VBG cord-321499-17n9tj70 79 10 from from IN cord-321499-17n9tj70 79 11 the the DT cord-321499-17n9tj70 79 12 past past NN cord-321499-17n9tj70 79 13 : : : cord-321499-17n9tj70 79 14 possible possible JJ cord-321499-17n9tj70 79 15 urgent urgent JJ cord-321499-17n9tj70 79 16 prevention prevention NN cord-321499-17n9tj70 79 17 and and CC cord-321499-17n9tj70 79 18 treatment treatment NN cord-321499-17n9tj70 79 19 options option NNS cord-321499-17n9tj70 79 20 for for IN cord-321499-17n9tj70 79 21 severe severe JJ cord-321499-17n9tj70 79 22 acute acute JJ cord-321499-17n9tj70 79 23 respiratory respiratory JJ cord-321499-17n9tj70 79 24 infections infection NNS cord-321499-17n9tj70 79 25 caused cause VBN cord-321499-17n9tj70 79 26 by by IN cord-321499-17n9tj70 79 27 2019-nCoV 2019-ncov CD cord-321499-17n9tj70 79 28 Remdesivir Remdesivir NNP cord-321499-17n9tj70 79 29 in in IN cord-321499-17n9tj70 79 30 adults adult NNS cord-321499-17n9tj70 79 31 with with IN cord-321499-17n9tj70 79 32 severe severe JJ cord-321499-17n9tj70 79 33 COVID-19 covid-19 NN cord-321499-17n9tj70 79 34 : : : cord-321499-17n9tj70 79 35 a a DT cord-321499-17n9tj70 79 36 randomised randomised JJ cord-321499-17n9tj70 79 37 , , , cord-321499-17n9tj70 79 38 double double JJ cord-321499-17n9tj70 79 39 - - HYPH cord-321499-17n9tj70 79 40 blind blind JJ cord-321499-17n9tj70 79 41 , , , cord-321499-17n9tj70 79 42 placebo placebo NN cord-321499-17n9tj70 79 43 - - HYPH cord-321499-17n9tj70 79 44 controlled control VBN cord-321499-17n9tj70 79 45 , , , cord-321499-17n9tj70 79 46 multicentre multicentre NNP cord-321499-17n9tj70 79 47 trial trial NN cord-321499-17n9tj70 79 48 Convalescent Convalescent NNP cord-321499-17n9tj70 79 49 plasma plasma NN cord-321499-17n9tj70 79 50 as as IN cord-321499-17n9tj70 79 51 a a DT cord-321499-17n9tj70 79 52 potential potential JJ cord-321499-17n9tj70 79 53 therapy therapy NN cord-321499-17n9tj70 79 54 for for IN cord-321499-17n9tj70 79 55 COVID-19 COVID-19 NNP cord-321499-17n9tj70 79 56 Barnum Barnum NNP cord-321499-17n9tj70 79 57 effect effect NN cord-321499-17n9tj70 79 58 " " '' cord-321499-17n9tj70 79 59 revisited revisit VBD cord-321499-17n9tj70 79 60 : : : cord-321499-17n9tj70 79 61 cognitive cognitive JJ cord-321499-17n9tj70 79 62 and and CC cord-321499-17n9tj70 79 63 motivational motivational JJ cord-321499-17n9tj70 79 64 factors factor NNS cord-321499-17n9tj70 79 65 in in IN cord-321499-17n9tj70 79 66 the the DT cord-321499-17n9tj70 79 67 acceptance acceptance NN cord-321499-17n9tj70 79 68 of of IN cord-321499-17n9tj70 79 69 personality personality NN cord-321499-17n9tj70 79 70 descriptions description NNS cord-321499-17n9tj70 80 1 Covid-19 Covid-19 NNP cord-321499-17n9tj70 80 2 does do VBZ cord-321499-17n9tj70 80 3 not not RB cord-321499-17n9tj70 80 4 lead lead VB cord-321499-17n9tj70 80 5 to to IN cord-321499-17n9tj70 80 6 a a DT cord-321499-17n9tj70 80 7 " " `` cord-321499-17n9tj70 80 8 typical typical JJ cord-321499-17n9tj70 80 9 " " '' cord-321499-17n9tj70 80 10 acute acute JJ cord-321499-17n9tj70 80 11 respiratory respiratory JJ cord-321499-17n9tj70 80 12 distress distress NN cord-321499-17n9tj70 80 13 syndrome syndrome NN cord-321499-17n9tj70 80 14 Acute acute JJ cord-321499-17n9tj70 80 15 respiratory respiratory JJ cord-321499-17n9tj70 80 16 distress distress NN cord-321499-17n9tj70 80 17 in in IN cord-321499-17n9tj70 80 18 adults adult NNS cord-321499-17n9tj70 80 19 Hyaline hyaline JJ cord-321499-17n9tj70 80 20 membrane membrane NN cord-321499-17n9tj70 80 21 disease disease NN cord-321499-17n9tj70 81 1 Acute acute JJ cord-321499-17n9tj70 81 2 respiratory respiratory JJ cord-321499-17n9tj70 81 3 distress distress NN cord-321499-17n9tj70 81 4 syndrome syndrome NN cord-321499-17n9tj70 81 5 : : : cord-321499-17n9tj70 82 1 the the DT cord-321499-17n9tj70 82 2 Berlin Berlin NNP cord-321499-17n9tj70 82 3 Definition Definition NNP cord-321499-17n9tj70 82 4 Reclassifying reclassify VBG cord-321499-17n9tj70 82 5 acute acute JJ cord-321499-17n9tj70 82 6 respiratory respiratory JJ cord-321499-17n9tj70 82 7 distress distress NN cord-321499-17n9tj70 82 8 syndrome syndrome NN cord-321499-17n9tj70 82 9 Do do VBP cord-321499-17n9tj70 82 10 the the DT cord-321499-17n9tj70 82 11 NIH NIH NNP cord-321499-17n9tj70 82 12 ARDS ARDS NNP cord-321499-17n9tj70 82 13 Clinical Clinical NNP cord-321499-17n9tj70 82 14 Trials Trials NNP cord-321499-17n9tj70 82 15 network network NN cord-321499-17n9tj70 82 16 PEEP peep NN cord-321499-17n9tj70 82 17 / / SYM cord-321499-17n9tj70 82 18 FiO FiO NNS cord-321499-17n9tj70 82 19 2 2 CD cord-321499-17n9tj70 82 20 tables table NNS cord-321499-17n9tj70 82 21 provide provide VBP cord-321499-17n9tj70 82 22 the the DT cord-321499-17n9tj70 82 23 best good JJS cord-321499-17n9tj70 82 24 evidence evidence NN cord-321499-17n9tj70 82 25 - - HYPH cord-321499-17n9tj70 82 26 based base VBN cord-321499-17n9tj70 82 27 guide guide NN cord-321499-17n9tj70 82 28 to to IN cord-321499-17n9tj70 82 29 balancing balance VBG cord-321499-17n9tj70 82 30 PEEP peep NN cord-321499-17n9tj70 82 31 and and CC cord-321499-17n9tj70 82 32 FiO FiO NNS cord-321499-17n9tj70 82 33 2 2 CD cord-321499-17n9tj70 82 34 settings setting NNS cord-321499-17n9tj70 82 35 in in IN cord-321499-17n9tj70 82 36 adults adult NNS cord-321499-17n9tj70 82 37 ? ? . cord-321499-17n9tj70 83 1 Static static JJ cord-321499-17n9tj70 83 2 and and CC cord-321499-17n9tj70 83 3 dynamic dynamic JJ cord-321499-17n9tj70 83 4 contributors contributor NNS cord-321499-17n9tj70 83 5 to to IN cord-321499-17n9tj70 83 6 ventilator ventilator NN cord-321499-17n9tj70 83 7 - - HYPH cord-321499-17n9tj70 83 8 induced induce VBN cord-321499-17n9tj70 83 9 lung lung NN cord-321499-17n9tj70 83 10 injury injury NN cord-321499-17n9tj70 83 11 in in IN cord-321499-17n9tj70 83 12 clinical clinical JJ cord-321499-17n9tj70 83 13 practice practice NN cord-321499-17n9tj70 83 14 . . . cord-321499-17n9tj70 84 1 Pressure pressure NN cord-321499-17n9tj70 84 2 , , , cord-321499-17n9tj70 84 3 energy energy NN cord-321499-17n9tj70 84 4 , , , cord-321499-17n9tj70 84 5 and and CC cord-321499-17n9tj70 84 6 power power NN cord-321499-17n9tj70 84 7 Management Management NNP cord-321499-17n9tj70 84 8 of of IN cord-321499-17n9tj70 84 9 Covid-19 covid-19 JJ cord-321499-17n9tj70 84 10 respiratory respiratory JJ cord-321499-17n9tj70 84 11 distress distress NN cord-321499-17n9tj70 84 12 Potential potential JJ cord-321499-17n9tj70 84 13 for for IN cord-321499-17n9tj70 84 14 lung lung NN cord-321499-17n9tj70 84 15 recruitment recruitment NN cord-321499-17n9tj70 84 16 and and CC cord-321499-17n9tj70 84 17 ventilation ventilation NN cord-321499-17n9tj70 84 18 - - HYPH cord-321499-17n9tj70 84 19 perfusion perfusion NN cord-321499-17n9tj70 84 20 mismatch mismatch NN cord-321499-17n9tj70 84 21 in in IN cord-321499-17n9tj70 84 22 patients patient NNS cord-321499-17n9tj70 84 23 with with IN cord-321499-17n9tj70 84 24 the the DT cord-321499-17n9tj70 84 25 acute acute JJ cord-321499-17n9tj70 84 26 respiratory respiratory JJ cord-321499-17n9tj70 84 27 distress distress NN cord-321499-17n9tj70 84 28 syndrome syndrome NN cord-321499-17n9tj70 84 29 from from IN cord-321499-17n9tj70 84 30 coronavirus coronavirus NN cord-321499-17n9tj70 84 31 disease disease NN cord-321499-17n9tj70 84 32 2019 2019 CD cord-321499-17n9tj70 84 33 Against against IN cord-321499-17n9tj70 84 34 pandemic pandemic NN cord-321499-17n9tj70 84 35 research research NN cord-321499-17n9tj70 84 36 exceptionalism exceptionalism NN cord-321499-17n9tj70 85 1 The the DT cord-321499-17n9tj70 85 2 perils peril NNS cord-321499-17n9tj70 85 3 of of IN cord-321499-17n9tj70 85 4 premature premature JJ cord-321499-17n9tj70 85 5 phenotyping phenotyping NN cord-321499-17n9tj70 85 6 in in IN cord-321499-17n9tj70 85 7 COVID COVID NNP cord-321499-17n9tj70 85 8 : : : cord-321499-17n9tj70 85 9 a a DT cord-321499-17n9tj70 85 10 call call NN cord-321499-17n9tj70 85 11 for for IN cord-321499-17n9tj70 85 12 caution caution NN cord-321499-17n9tj70 85 13 COVID-19 COVID-19 NNP cord-321499-17n9tj70 85 14 pneumonia pneumonia NN cord-321499-17n9tj70 85 15 : : : cord-321499-17n9tj70 85 16 different different JJ cord-321499-17n9tj70 85 17 respiratory respiratory JJ cord-321499-17n9tj70 85 18 treatments treatment NNS cord-321499-17n9tj70 85 19 for for IN cord-321499-17n9tj70 85 20 different different JJ cord-321499-17n9tj70 85 21 phenotypes phenotype NNS cord-321499-17n9tj70 85 22 ? ? .