id	sid	tid	token	lemma	pos
cord-355208-hpldjsc5	1	1	key	key	JJ
cord-355208-hpldjsc5	2	1	:	:	:
cord-355208-hpldjsc5	2	2	cord-355208-hpldjsc5	cord-355208-hpldjsc5	NNS
cord-355208-hpldjsc5	2	3	authors	author	NNS
cord-355208-hpldjsc5	2	4	:	:	:
cord-355208-hpldjsc5	2	5	Leisman	Leisman	NNP
cord-355208-hpldjsc5	2	6	,	,	,
cord-355208-hpldjsc5	2	7	Daniel	Daniel	NNP
cord-355208-hpldjsc5	2	8	E.	E.	NNP
cord-355208-hpldjsc5	2	9	;	;	:
cord-355208-hpldjsc5	3	1	Deutschman	Deutschman	NNP
cord-355208-hpldjsc5	3	2	,	,	,
cord-355208-hpldjsc5	3	3	Clifford	Clifford	NNP
cord-355208-hpldjsc5	3	4	S.	S.	NNP
cord-355208-hpldjsc5	3	5	;	;	:
cord-355208-hpldjsc5	3	6	Legrand	Legrand	NNP
cord-355208-hpldjsc5	3	7	,	,	,
cord-355208-hpldjsc5	3	8	Matthieu	Matthieu	NNP
cord-355208-hpldjsc5	3	9	title	title	NN
cord-355208-hpldjsc5	3	10	:	:	:
cord-355208-hpldjsc5	3	11	Facing	face	VBG
cord-355208-hpldjsc5	3	12	COVID-19	covid-19	CD
cord-355208-hpldjsc5	3	13	in	in	IN
cord-355208-hpldjsc5	3	14	the	the	DT
cord-355208-hpldjsc5	3	15	ICU	ICU	NNP
cord-355208-hpldjsc5	3	16	:	:	:
cord-355208-hpldjsc5	3	17	vascular	vascular	JJ
cord-355208-hpldjsc5	3	18	dysfunction	dysfunction	NN
cord-355208-hpldjsc5	3	19	,	,	,
cord-355208-hpldjsc5	3	20	thrombosis	thrombosis	NN
cord-355208-hpldjsc5	3	21	,	,	,
cord-355208-hpldjsc5	3	22	and	and	CC
cord-355208-hpldjsc5	3	23	dysregulated	dysregulated	JJ
cord-355208-hpldjsc5	3	24	inflammation	inflammation	NN
cord-355208-hpldjsc5	3	25	date	date	NN
cord-355208-hpldjsc5	3	26	:	:	:
cord-355208-hpldjsc5	3	27	2020	2020	CD
cord-355208-hpldjsc5	3	28	-	-	HYPH
cord-355208-hpldjsc5	3	29	04	04	CD
cord-355208-hpldjsc5	3	30	-	-	HYPH
cord-355208-hpldjsc5	3	31	28	28	CD
cord-355208-hpldjsc5	3	32	journal	journal	NN
cord-355208-hpldjsc5	3	33	:	:	:
cord-355208-hpldjsc5	3	34	Intensive	Intensive	NNP
cord-355208-hpldjsc5	3	35	Care	care	NN
cord-355208-hpldjsc5	3	36	Med	Med	NNP
cord-355208-hpldjsc5	3	37	DOI	doi	NN
cord-355208-hpldjsc5	3	38	:	:	:
cord-355208-hpldjsc5	3	39	10.1007	10.1007	CD
cord-355208-hpldjsc5	3	40	/	/	SYM
cord-355208-hpldjsc5	3	41	s00134	s00134	VBN
cord-355208-hpldjsc5	3	42	-	-	HYPH
cord-355208-hpldjsc5	3	43	020	020	CD
cord-355208-hpldjsc5	3	44	-	-	HYPH
cord-355208-hpldjsc5	3	45	06059	06059	CD
cord-355208-hpldjsc5	3	46	-	-	SYM
cord-355208-hpldjsc5	3	47	6	6	CD
cord-355208-hpldjsc5	3	48	sha	sha	NN
cord-355208-hpldjsc5	3	49	:	:	:
cord-355208-hpldjsc5	4	1	f2638c7eb97ffdb517aa05fc26353f1af3cd8305	f2638c7eb97ffdb517aa05fc26353f1af3cd8305	NNP
cord-355208-hpldjsc5	4	2	doc_id	doc_id	CD
cord-355208-hpldjsc5	4	3	:	:	:
cord-355208-hpldjsc5	4	4	355208	355208	CD
cord-355208-hpldjsc5	4	5	cord_uid	cord_uid	NNS
cord-355208-hpldjsc5	4	6	:	:	:
cord-355208-hpldjsc5	5	1	hpldjsc5	hpldjsc5	NN
cord-355208-hpldjsc5	6	1	nan	nan	NNP
cord-355208-hpldjsc5	6	2	Published	Published	NNP
cord-355208-hpldjsc5	6	3	data	datum	NNS
cord-355208-hpldjsc5	6	4	[	[	-LRB-
cord-355208-hpldjsc5	6	5	1	1	CD
cord-355208-hpldjsc5	6	6	,	,	,
cord-355208-hpldjsc5	6	7	2	2	CD
cord-355208-hpldjsc5	6	8	]	]	-RRB-
cord-355208-hpldjsc5	6	9	,	,	,
cord-355208-hpldjsc5	6	10	anecdotal	anecdotal	JJ
cord-355208-hpldjsc5	6	11	observations	observation	NNS
cord-355208-hpldjsc5	6	12	,	,	,
cord-355208-hpldjsc5	6	13	and	and	CC
cord-355208-hpldjsc5	6	14	discussions	discussion	NNS
cord-355208-hpldjsc5	6	15	with	with	IN
cord-355208-hpldjsc5	6	16	colleagues	colleague	NNS
cord-355208-hpldjsc5	6	17	worldwide	worldwide	RB
cord-355208-hpldjsc5	6	18	indicate	indicate	VBP
cord-355208-hpldjsc5	6	19	that	that	IN
cord-355208-hpldjsc5	6	20	COVIDinduced	covidinduce	VBN
cord-355208-hpldjsc5	6	21	respiratory	respiratory	JJ
cord-355208-hpldjsc5	6	22	phenotypes	phenotype	NNS
cord-355208-hpldjsc5	6	23	are	be	VBP
cord-355208-hpldjsc5	6	24	distinct	distinct	JJ
cord-355208-hpldjsc5	6	25	from	from	IN
cord-355208-hpldjsc5	6	26	typical	typical	JJ
cord-355208-hpldjsc5	6	27	ARDS	ARDS	NNP
cord-355208-hpldjsc5	6	28	in	in	IN
cord-355208-hpldjsc5	6	29	several	several	JJ
cord-355208-hpldjsc5	6	30	ways	way	NNS
cord-355208-hpldjsc5	6	31	[	[	-LRB-
cord-355208-hpldjsc5	6	32	2	2	CD
cord-355208-hpldjsc5	6	33	]	]	-RRB-
cord-355208-hpldjsc5	6	34	.	.	.
cord-355208-hpldjsc5	7	1	COVID-19	covid-19	JJ
cord-355208-hpldjsc5	7	2	patients	patient	NNS
cord-355208-hpldjsc5	7	3	develop	develop	VBP
cord-355208-hpldjsc5	7	4	profound	profound	JJ
cord-355208-hpldjsc5	7	5	hypoxemia	hypoxemia	NN
cord-355208-hpldjsc5	7	6	early	early	RB
cord-355208-hpldjsc5	7	7	in	in	IN
cord-355208-hpldjsc5	7	8	their	-PRON-	PRP$
cord-355208-hpldjsc5	7	9	disease	disease	NN
cord-355208-hpldjsc5	7	10	course	course	NN
cord-355208-hpldjsc5	7	11	.	.	.
cord-355208-hpldjsc5	8	1	However	however	RB
cord-355208-hpldjsc5	8	2	,	,	,
cord-355208-hpldjsc5	8	3	overt	overt	JJ
cord-355208-hpldjsc5	8	4	respiratory	respiratory	JJ
cord-355208-hpldjsc5	8	5	dysfunction	dysfunction	NN
cord-355208-hpldjsc5	8	6	at	at	IN
cord-355208-hpldjsc5	8	7	these	these	DT
cord-355208-hpldjsc5	8	8	early	early	JJ
cord-355208-hpldjsc5	8	9	stages	stage	NNS
cord-355208-hpldjsc5	8	10	is	be	VBZ
cord-355208-hpldjsc5	8	11	unusual	unusual	JJ
cord-355208-hpldjsc5	8	12	.	.	.
cord-355208-hpldjsc5	9	1	Pulmonary	pulmonary	JJ
cord-355208-hpldjsc5	9	2	compliance	compliance	NN
cord-355208-hpldjsc5	9	3	in	in	IN
cord-355208-hpldjsc5	9	4	intubated	intubate	VBN
cord-355208-hpldjsc5	9	5	COVID-19	COVID-19	NNP
cord-355208-hpldjsc5	9	6	patients	patient	NNS
cord-355208-hpldjsc5	9	7	appears	appear	VBZ
cord-355208-hpldjsc5	9	8	to	to	TO
cord-355208-hpldjsc5	9	9	be	be	VB
cord-355208-hpldjsc5	9	10	only	only	RB
cord-355208-hpldjsc5	9	11	modestly	modestly	RB
cord-355208-hpldjsc5	9	12	decreased	decrease	VBN
cord-355208-hpldjsc5	9	13	,	,	,
cord-355208-hpldjsc5	9	14	and	and	CC
cord-355208-hpldjsc5	9	15	patients	patient	NNS
cord-355208-hpldjsc5	9	16	are	be	VBP
cord-355208-hpldjsc5	9	17	therefore	therefore	RB
cord-355208-hpldjsc5	9	18	relatively	relatively	RB
cord-355208-hpldjsc5	9	19	easy	easy	JJ
cord-355208-hpldjsc5	9	20	to	to	TO
cord-355208-hpldjsc5	9	21	ventilate	ventilate	VB
cord-355208-hpldjsc5	9	22	[	[	-LRB-
cord-355208-hpldjsc5	9	23	1	1	CD
cord-355208-hpldjsc5	9	24	]	]	-RRB-
cord-355208-hpldjsc5	9	25	.	.	.
cord-355208-hpldjsc5	10	1	Gattinoni	Gattinoni	NNP
cord-355208-hpldjsc5	10	2	et	et	NNP
cord-355208-hpldjsc5	10	3	al	al	NNP
cord-355208-hpldjsc5	10	4	.	.	.
cord-355208-hpldjsc5	11	1	[	[	-LRB-
cord-355208-hpldjsc5	11	2	1	1	CD
cord-355208-hpldjsc5	11	3	]	]	-RRB-
cord-355208-hpldjsc5	11	4	described	describe	VBN
cord-355208-hpldjsc5	11	5	hyperperfusion	hyperperfusion	NN
cord-355208-hpldjsc5	11	6	of	of	IN
cord-355208-hpldjsc5	11	7	poorly	poorly	RB
cord-355208-hpldjsc5	11	8	ventilated	ventilate	VBN
cord-355208-hpldjsc5	11	9	lung	lung	NN
cord-355208-hpldjsc5	11	10	,	,	,
cord-355208-hpldjsc5	11	11	perhaps	perhaps	RB
cord-355208-hpldjsc5	11	12	due	due	IN
cord-355208-hpldjsc5	11	13	to	to	IN
cord-355208-hpldjsc5	11	14	vasodilation	vasodilation	NN
cord-355208-hpldjsc5	11	15	and	and	CC
cord-355208-hpldjsc5	11	16	the	the	DT
cord-355208-hpldjsc5	11	17	loss	loss	NN
cord-355208-hpldjsc5	11	18	of	of	IN
cord-355208-hpldjsc5	11	19	hypoxic	hypoxic	JJ
cord-355208-hpldjsc5	11	20	vasoconstriction	vasoconstriction	NN
cord-355208-hpldjsc5	11	21	.	.	.
cord-355208-hpldjsc5	12	1	While	while	IN
cord-355208-hpldjsc5	12	2	benefit	benefit	NN
cord-355208-hpldjsc5	12	3	from	from	IN
cord-355208-hpldjsc5	12	4	low	low	JJ
cord-355208-hpldjsc5	12	5	-	-	HYPH
cord-355208-hpldjsc5	12	6	tomoderate	tomoderate	NN
cord-355208-hpldjsc5	12	7	levels	level	NNS
cord-355208-hpldjsc5	12	8	of	of	IN
cord-355208-hpldjsc5	12	9	PEEP	peep	NN
cord-355208-hpldjsc5	12	10	and	and	CC
cord-355208-hpldjsc5	12	11	prone	prone	JJ
cord-355208-hpldjsc5	12	12	positioning	positioning	NN
cord-355208-hpldjsc5	12	13	have	have	VBP
cord-355208-hpldjsc5	12	14	been	be	VBN
cord-355208-hpldjsc5	12	15	noted	note	VBN
cord-355208-hpldjsc5	12	16	,	,	,
cord-355208-hpldjsc5	12	17	these	these	DT
cord-355208-hpldjsc5	12	18	authors	author	NNS
cord-355208-hpldjsc5	12	19	suggest	suggest	VBP
cord-355208-hpldjsc5	12	20	that	that	IN
cord-355208-hpldjsc5	12	21	they	-PRON-	PRP
cord-355208-hpldjsc5	12	22	result	result	VBP
cord-355208-hpldjsc5	12	23	more	more	JJR
cord-355208-hpldjsc5	12	24	from	from	IN
cord-355208-hpldjsc5	12	25	hemodynamics	hemodynamic	NNS
cord-355208-hpldjsc5	12	26	effects	effect	NNS
cord-355208-hpldjsc5	12	27	than	than	IN
cord-355208-hpldjsc5	12	28	lung	lung	NN
cord-355208-hpldjsc5	12	29	recruitment	recruitment	NN
cord-355208-hpldjsc5	12	30	[	[	-LRB-
cord-355208-hpldjsc5	12	31	1	1	CD
cord-355208-hpldjsc5	12	32	]	]	-RRB-
cord-355208-hpldjsc5	12	33	.	.	.
cord-355208-hpldjsc5	13	1	Later	later	RB
cord-355208-hpldjsc5	13	2	in	in	IN
cord-355208-hpldjsc5	13	3	the	the	DT
cord-355208-hpldjsc5	13	4	course	course	NN
cord-355208-hpldjsc5	13	5	of	of	IN
cord-355208-hpldjsc5	13	6	COVID-19	COVID-19	NNP
cord-355208-hpldjsc5	13	7	,	,	,
cord-355208-hpldjsc5	13	8	some	some	DT
cord-355208-hpldjsc5	13	9	patients	patient	NNS
cord-355208-hpldjsc5	13	10	develop	develop	VBP
cord-355208-hpldjsc5	13	11	a	a	DT
cord-355208-hpldjsc5	13	12	phenotype	phenotype	NN
cord-355208-hpldjsc5	13	13	more	more	RBR
cord-355208-hpldjsc5	13	14	consistent	consistent	JJ
cord-355208-hpldjsc5	13	15	with	with	IN
cord-355208-hpldjsc5	13	16	ARDS	ARDS	NNP
cord-355208-hpldjsc5	13	17	[	[	-LRB-
cord-355208-hpldjsc5	13	18	1	1	CD
cord-355208-hpldjsc5	13	19	,	,	,
cord-355208-hpldjsc5	13	20	2	2	CD
cord-355208-hpldjsc5	13	21	]	]	-RRB-
cord-355208-hpldjsc5	13	22	.	.	.
cord-355208-hpldjsc5	14	1	The	the	DT
cord-355208-hpldjsc5	14	2	reported	reported	JJ
cord-355208-hpldjsc5	14	3	inflammatory	inflammatory	JJ
cord-355208-hpldjsc5	14	4	response	response	NN
cord-355208-hpldjsc5	14	5	in	in	IN
cord-355208-hpldjsc5	14	6	COVID-19	COVID-19	NNP
cord-355208-hpldjsc5	14	7	is	be	VBZ
cord-355208-hpldjsc5	14	8	also	also	RB
cord-355208-hpldjsc5	14	9	not	not	RB
cord-355208-hpldjsc5	14	10	consistent	consistent	JJ
cord-355208-hpldjsc5	14	11	with	with	IN
cord-355208-hpldjsc5	14	12	either	either	CC
cord-355208-hpldjsc5	14	13	typical	typical	JJ
cord-355208-hpldjsc5	14	14	ARDS	ARDS	NNP
cord-355208-hpldjsc5	14	15	or	or	CC
cord-355208-hpldjsc5	14	16	cytokine	cytokine	NN
cord-355208-hpldjsc5	14	17	-	-	HYPH
cord-355208-hpldjsc5	14	18	release	release	NN
cord-355208-hpldjsc5	14	19	syndromes	syndrome	NNS
cord-355208-hpldjsc5	14	20	(	(	-LRB-
cord-355208-hpldjsc5	14	21	CRS	CRS	NNP
cord-355208-hpldjsc5	14	22	)	)	-RRB-
cord-355208-hpldjsc5	14	23	or	or	CC
cord-355208-hpldjsc5	14	24	"	"	``
cord-355208-hpldjsc5	14	25	cytokine	cytokine	JJ
cord-355208-hpldjsc5	14	26	storm	storm	NN
cord-355208-hpldjsc5	14	27	.	.	.
cord-355208-hpldjsc5	14	28	"	"	''
cord-355208-hpldjsc5	15	1	Qin	Qin	NNP
cord-355208-hpldjsc5	15	2	et	et	NNP
cord-355208-hpldjsc5	15	3	al	al	NNP
cord-355208-hpldjsc5	15	4	.	.	.
cord-355208-hpldjsc5	16	1	[	[	-LRB-
cord-355208-hpldjsc5	16	2	3	3	LS
cord-355208-hpldjsc5	16	3	]	]	-RRB-
cord-355208-hpldjsc5	16	4	report	report	NN
cord-355208-hpldjsc5	16	5	mean	mean	NN
cord-355208-hpldjsc5	16	6	interleukin-6	interleukin-6	NNP
cord-355208-hpldjsc5	16	7	levels	level	NNS
cord-355208-hpldjsc5	16	8	were	be	VBD
cord-355208-hpldjsc5	16	9	25	25	CD
cord-355208-hpldjsc5	16	10	(	(	-LRB-
cord-355208-hpldjsc5	16	11	SD	sd	NN
cord-355208-hpldjsc5	16	12	:	:	:
cord-355208-hpldjsc5	16	13	10	10	CD
cord-355208-hpldjsc5	16	14	-	-	SYM
cord-355208-hpldjsc5	16	15	55	55	CD
cord-355208-hpldjsc5	16	16	)	)	-RRB-
cord-355208-hpldjsc5	16	17	pg	pg	NN
cord-355208-hpldjsc5	16	18	/	/	SYM
cord-355208-hpldjsc5	16	19	mL	ml	NN
cord-355208-hpldjsc5	16	20	(	(	-LRB-
cord-355208-hpldjsc5	16	21	normal	normal	JJ
cord-355208-hpldjsc5	16	22	range	range	NN
cord-355208-hpldjsc5	16	23	:	:	:
cord-355208-hpldjsc5	16	24	7	7	CD
cord-355208-hpldjsc5	16	25	pg	pg	NN
cord-355208-hpldjsc5	16	26	/	/	SYM
cord-355208-hpldjsc5	16	27	mL	mL	NNP
cord-355208-hpldjsc5	16	28	)	)	-RRB-
cord-355208-hpldjsc5	16	29	.	.	.
cord-355208-hpldjsc5	17	1	Other	other	JJ
cord-355208-hpldjsc5	17	2	smaller	small	JJR
cord-355208-hpldjsc5	17	3	COVID-19	covid-19	JJ
cord-355208-hpldjsc5	17	4	reports	report	NNS
cord-355208-hpldjsc5	17	5	have	have	VBP
cord-355208-hpldjsc5	17	6	ranged	range	VBN
cord-355208-hpldjsc5	17	7	from	from	IN
cord-355208-hpldjsc5	17	8	7	7	CD
cord-355208-hpldjsc5	17	9	to	to	TO
cord-355208-hpldjsc5	17	10	125	125	CD
cord-355208-hpldjsc5	17	11	pg/	pg/	NNS
cord-355208-hpldjsc5	18	1	mL.	mL.	NNP
cord-355208-hpldjsc5	18	2	These	these	DT
cord-355208-hpldjsc5	18	3	findings	finding	NNS
cord-355208-hpldjsc5	18	4	contrast	contrast	NN
cord-355208-hpldjsc5	18	5	with	with	IN
cord-355208-hpldjsc5	18	6	interleukin-6	interleukin-6	NNP
cord-355208-hpldjsc5	18	7	elevations	elevation	NNS
cord-355208-hpldjsc5	18	8	seen	see	VBN
cord-355208-hpldjsc5	18	9	in	in	IN
cord-355208-hpldjsc5	18	10	typical	typical	JJ
cord-355208-hpldjsc5	18	11	ARDS	ARDS	NNP
cord-355208-hpldjsc5	18	12	and	and	CC
cord-355208-hpldjsc5	18	13	in	in	IN
cord-355208-hpldjsc5	18	14	CRS	CRS	NNP
cord-355208-hpldjsc5	18	15	.	.	.
cord-355208-hpldjsc5	19	1	Sinha	Sinha	NNP
cord-355208-hpldjsc5	19	2	et	et	NNP
cord-355208-hpldjsc5	19	3	al	al	NNP
cord-355208-hpldjsc5	19	4	.	.	.
cord-355208-hpldjsc5	20	1	report	report	NN
cord-355208-hpldjsc5	20	2	mean	mean	NNP
cord-355208-hpldjsc5	20	3	interleukin-6	interleukin-6	NNP
cord-355208-hpldjsc5	20	4	levels	level	NNS
cord-355208-hpldjsc5	20	5	of	of	IN
cord-355208-hpldjsc5	20	6	282	282	CD
cord-355208-hpldjsc5	20	7	(	(	-LRB-
cord-355208-hpldjsc5	20	8	111	111	CD
cord-355208-hpldjsc5	20	9	-	-	SYM
cord-355208-hpldjsc5	20	10	600	600	CD
cord-355208-hpldjsc5	20	11	)	)	-RRB-
cord-355208-hpldjsc5	20	12	pg	pg	NN
cord-355208-hpldjsc5	20	13	/	/	SYM
cord-355208-hpldjsc5	20	14	mL	ml	NN
cord-355208-hpldjsc5	20	15	in	in	IN
cord-355208-hpldjsc5	20	16	"	"	``
cord-355208-hpldjsc5	20	17	hypoinflammatory	hypoinflammatory	JJ
cord-355208-hpldjsc5	20	18	"	"	''
cord-355208-hpldjsc5	20	19	ARDS	ARDS	NNP
cord-355208-hpldjsc5	20	20	[	[	-LRB-
cord-355208-hpldjsc5	20	21	9	9	CD
cord-355208-hpldjsc5	20	22	]	]	-RRB-
cord-355208-hpldjsc5	20	23	and	and	CC
cord-355208-hpldjsc5	20	24	1618	1618	CD
cord-355208-hpldjsc5	20	25	(	(	-LRB-
cord-355208-hpldjsc5	20	26	517	517	CD
cord-355208-hpldjsc5	20	27	-	-	HYPH
cord-355208-hpldjsc5	20	28	3205	3205	CD
cord-355208-hpldjsc5	20	29	)	)	-RRB-
cord-355208-hpldjsc5	21	1	pg	pg	NNP
cord-355208-hpldjsc5	21	2	/	/	SYM
cord-355208-hpldjsc5	21	3	mL	mL	NNP
cord-355208-hpldjsc5	21	4	in	in	IN
cord-355208-hpldjsc5	21	5	hyperinflammatory	hyperinflammatory	JJ
cord-355208-hpldjsc5	21	6	ARDS	ARDS	NNP
cord-355208-hpldjsc5	21	7	[	[	-LRB-
cord-355208-hpldjsc5	21	8	4	4	CD
cord-355208-hpldjsc5	21	9	]	]	-RRB-
cord-355208-hpldjsc5	21	10	,	,	.
cord-355208-hpldjsc5	22	1	10-to	10-to	CD
cord-355208-hpldjsc5	22	2	60-fold	60-fold	CD
cord-355208-hpldjsc5	22	3	higher	high	JJR
cord-355208-hpldjsc5	22	4	than	than	IN
cord-355208-hpldjsc5	22	5	reported	report	VBN
cord-355208-hpldjsc5	22	6	in	in	IN
cord-355208-hpldjsc5	22	7	the	the	DT
cord-355208-hpldjsc5	22	8	Wuhan	Wuhan	NNP
cord-355208-hpldjsc5	22	9	data	datum	NNS
cord-355208-hpldjsc5	22	10	.	.	.
cord-355208-hpldjsc5	23	1	Among	among	IN
cord-355208-hpldjsc5	23	2	CRS	CRS	NNP
cord-355208-hpldjsc5	23	3	patients	patient	NNS
cord-355208-hpldjsc5	23	4	,	,	,
cord-355208-hpldjsc5	23	5	mean	mean	JJ
cord-355208-hpldjsc5	23	6	interleukin-6	interleukin-6	NNP
cord-355208-hpldjsc5	23	7	levels	level	NNS
cord-355208-hpldjsc5	23	8	are	be	VBP
cord-355208-hpldjsc5	23	9	frequently	frequently	RB
cord-355208-hpldjsc5	23	10	as	as	RB
cord-355208-hpldjsc5	23	11	high	high	JJ
cord-355208-hpldjsc5	23	12	as	as	IN
cord-355208-hpldjsc5	23	13	10,000	10,000	CD
cord-355208-hpldjsc5	23	14	pg	pg	NN
cord-355208-hpldjsc5	23	15	/	/	SYM
cord-355208-hpldjsc5	23	16	mL	mL	NNP
cord-355208-hpldjsc5	23	17	[	[	-LRB-
cord-355208-hpldjsc5	23	18	5	5	CD
cord-355208-hpldjsc5	23	19	]	]	-RRB-
cord-355208-hpldjsc5	23	20	.	.	.
cord-355208-hpldjsc5	24	1	Other	other	JJ
cord-355208-hpldjsc5	24	2	inflammatory	inflammatory	JJ
cord-355208-hpldjsc5	24	3	cytokines	cytokine	NNS
cord-355208-hpldjsc5	24	4	(	(	-LRB-
cord-355208-hpldjsc5	24	5	e.g.	e.g.	RB
cord-355208-hpldjsc5	24	6	,	,	,
cord-355208-hpldjsc5	24	7	interleukin-8	interleukin-8	NNP
cord-355208-hpldjsc5	24	8	,	,	,
cord-355208-hpldjsc5	24	9	interleukin-1β	interleukin-1β	LS
cord-355208-hpldjsc5	24	10	)	)	-RRB-
cord-355208-hpldjsc5	24	11	demonstrate	demonstrate	VBP
cord-355208-hpldjsc5	24	12	similar	similar	JJ
cord-355208-hpldjsc5	24	13	patterns	pattern	NNS
cord-355208-hpldjsc5	24	14	.	.	.
cord-355208-hpldjsc5	25	1	In	in	IN
cord-355208-hpldjsc5	25	2	summary	summary	NN
cord-355208-hpldjsc5	25	3	,	,	,
cord-355208-hpldjsc5	25	4	COVID-19	COVID-19	NNP
cord-355208-hpldjsc5	25	5	is	be	VBZ
cord-355208-hpldjsc5	25	6	associated	associate	VBN
cord-355208-hpldjsc5	25	7	with	with	IN
cord-355208-hpldjsc5	25	8	only	only	JJ
cord-355208-hpldjsc5	25	9	mild	mild	JJ
cord-355208-hpldjsc5	25	10	inflammatory	inflammatory	JJ
cord-355208-hpldjsc5	25	11	cytokine	cytokine	NN
cord-355208-hpldjsc5	25	12	elevation	elevation	NN
cord-355208-hpldjsc5	25	13	and	and	CC
cord-355208-hpldjsc5	25	14	demonstrates	demonstrate	VBZ
cord-355208-hpldjsc5	25	15	physiology	physiology	NN
cord-355208-hpldjsc5	25	16	and	and	CC
cord-355208-hpldjsc5	25	17	immunology	immunology	NN
cord-355208-hpldjsc5	25	18	that	that	WDT
cord-355208-hpldjsc5	25	19	are	be	VBP
cord-355208-hpldjsc5	25	20	difficult	difficult	JJ
cord-355208-hpldjsc5	25	21	to	to	TO
cord-355208-hpldjsc5	25	22	reconcile	reconcile	VB
cord-355208-hpldjsc5	25	23	with	with	IN
cord-355208-hpldjsc5	25	24	ARDS	ARDS	NNP
cord-355208-hpldjsc5	25	25	or	or	CC
cord-355208-hpldjsc5	25	26	CRS	CRS	NNP
cord-355208-hpldjsc5	25	27	.	.	.
cord-355208-hpldjsc5	26	1	An	an	DT
cord-355208-hpldjsc5	26	2	alternative	alternative	JJ
cord-355208-hpldjsc5	26	3	mechanism	mechanism	NN
cord-355208-hpldjsc5	26	4	of	of	IN
cord-355208-hpldjsc5	26	5	disease	disease	NN
cord-355208-hpldjsc5	26	6	therefore	therefore	RB
cord-355208-hpldjsc5	26	7	seems	seem	VBZ
cord-355208-hpldjsc5	26	8	likely	likely	JJ
cord-355208-hpldjsc5	26	9	.	.	.
cord-355208-hpldjsc5	27	1	The	the	DT
cord-355208-hpldjsc5	27	2	combination	combination	NN
cord-355208-hpldjsc5	27	3	of	of	IN
cord-355208-hpldjsc5	27	4	observed	observed	JJ
cord-355208-hpldjsc5	27	5	physiology	physiology	NN
cord-355208-hpldjsc5	27	6	and	and	CC
cord-355208-hpldjsc5	27	7	emerging	emerge	VBG
cord-355208-hpldjsc5	27	8	pathologic	pathologic	JJ
cord-355208-hpldjsc5	27	9	evidence	evidence	NN
cord-355208-hpldjsc5	27	10	points	point	VBZ
cord-355208-hpldjsc5	27	11	toward	toward	IN
cord-355208-hpldjsc5	27	12	a	a	DT
cord-355208-hpldjsc5	27	13	vascular	vascular	JJ
cord-355208-hpldjsc5	27	14	disease	disease	NN
cord-355208-hpldjsc5	27	15	process	process	NN
cord-355208-hpldjsc5	27	16	as	as	IN
cord-355208-hpldjsc5	27	17	contributing	contribute	VBG
cord-355208-hpldjsc5	27	18	factor	factor	NN
cord-355208-hpldjsc5	27	19	in	in	IN
cord-355208-hpldjsc5	27	20	COVID-19	covid-19	JJ
cord-355208-hpldjsc5	27	21	pathogenesis	pathogenesis	NN
cord-355208-hpldjsc5	27	22	.	.	.
cord-355208-hpldjsc5	28	1	Pulmonary	pulmonary	JJ
cord-355208-hpldjsc5	28	2	shunting	shunting	NN
cord-355208-hpldjsc5	28	3	is	be	VBZ
cord-355208-hpldjsc5	28	4	consistent	consistent	JJ
cord-355208-hpldjsc5	28	5	with	with	IN
cord-355208-hpldjsc5	28	6	intense	intense	JJ
cord-355208-hpldjsc5	28	7	vasodilation	vasodilation	NN
cord-355208-hpldjsc5	28	8	and	and	CC
cord-355208-hpldjsc5	28	9	endothelial	endothelial	JJ
cord-355208-hpldjsc5	28	10	dysfunction	dysfunction	NN
cord-355208-hpldjsc5	28	11	.	.	.
cord-355208-hpldjsc5	29	1	The	the	DT
cord-355208-hpldjsc5	29	2	observation	observation	NN
cord-355208-hpldjsc5	29	3	that	that	IN
cord-355208-hpldjsc5	29	4	89	89	CD
cord-355208-hpldjsc5	29	5	%	%	NN
cord-355208-hpldjsc5	29	6	of	of	IN
cord-355208-hpldjsc5	29	7	hospitalized	hospitalize	VBN
cord-355208-hpldjsc5	29	8	patients	patient	NNS
cord-355208-hpldjsc5	29	9	in	in	IN
cord-355208-hpldjsc5	29	10	Rome	Rome	NNP
cord-355208-hpldjsc5	29	11	showed	show	VBD
cord-355208-hpldjsc5	29	12	subsegmental	subsegmental	JJ
cord-355208-hpldjsc5	29	13	vascular	vascular	JJ
cord-355208-hpldjsc5	29	14	enlargement	enlargement	NN
cord-355208-hpldjsc5	29	15	on	on	IN
cord-355208-hpldjsc5	29	16	their	-PRON-	PRP$
cord-355208-hpldjsc5	29	17	admission	admission	NN
cord-355208-hpldjsc5	29	18	computed	compute	VBN
cord-355208-hpldjsc5	29	19	tomography	tomography	NN
cord-355208-hpldjsc5	29	20	scan	scan	NN
cord-355208-hpldjsc5	29	21	supports	support	VBZ
cord-355208-hpldjsc5	29	22	this	this	DT
cord-355208-hpldjsc5	29	23	view	view	NN
cord-355208-hpldjsc5	29	24	[	[	-LRB-
cord-355208-hpldjsc5	29	25	6	6	CD
cord-355208-hpldjsc5	29	26	]	]	-RRB-
cord-355208-hpldjsc5	29	27	.	.	.
cord-355208-hpldjsc5	30	1	Reports	report	NNS
cord-355208-hpldjsc5	30	2	of	of	IN
cord-355208-hpldjsc5	30	3	increased	increase	VBN
cord-355208-hpldjsc5	30	4	respiratory	respiratory	JJ
cord-355208-hpldjsc5	30	5	dead	dead	JJ
cord-355208-hpldjsc5	30	6	space	space	NN
cord-355208-hpldjsc5	30	7	suggest	suggest	VBP
cord-355208-hpldjsc5	30	8	lung	lung	NN
cord-355208-hpldjsc5	30	9	-	-	HYPH
cord-355208-hpldjsc5	30	10	vascular	vascular	JJ
cord-355208-hpldjsc5	30	11	thrombosis	thrombosis	NN
cord-355208-hpldjsc5	30	12	from	from	IN
cord-355208-hpldjsc5	30	13	thrombotic	thrombotic	JJ
cord-355208-hpldjsc5	30	14	microangiopathy	microangiopathy	NNP
cord-355208-hpldjsc5	30	15	or	or	CC
cord-355208-hpldjsc5	30	16	pulmonary	pulmonary	JJ
cord-355208-hpldjsc5	30	17	embolism	embolism	NN
cord-355208-hpldjsc5	30	18	.	.	.
cord-355208-hpldjsc5	31	1	The	the	DT
cord-355208-hpldjsc5	31	2	latter	latter	JJ
cord-355208-hpldjsc5	31	3	was	be	VBD
cord-355208-hpldjsc5	31	4	recently	recently	RB
cord-355208-hpldjsc5	31	5	reported	report	VBN
cord-355208-hpldjsc5	31	6	in	in	IN
cord-355208-hpldjsc5	31	7	up	up	IN
cord-355208-hpldjsc5	31	8	to	to	TO
cord-355208-hpldjsc5	31	9	40	40	CD
cord-355208-hpldjsc5	31	10	%	%	NN
cord-355208-hpldjsc5	31	11	of	of	IN
cord-355208-hpldjsc5	31	12	hospitalized	hospitalize	VBN
cord-355208-hpldjsc5	31	13	COVID-19	covid-19	CD
cord-355208-hpldjsc5	31	14	patients	patient	NNS
cord-355208-hpldjsc5	31	15	[	[	-LRB-
cord-355208-hpldjsc5	31	16	7	7	CD
cord-355208-hpldjsc5	31	17	]	]	-RRB-
cord-355208-hpldjsc5	31	18	.	.	.
cord-355208-hpldjsc5	32	1	Autopsies	autopsy	NNS
cord-355208-hpldjsc5	32	2	performed	perform	VBN
cord-355208-hpldjsc5	32	3	on	on	IN
cord-355208-hpldjsc5	32	4	patients	patient	NNS
cord-355208-hpldjsc5	32	5	who	who	WP
cord-355208-hpldjsc5	32	6	died	die	VBD
cord-355208-hpldjsc5	32	7	early	early	RB
cord-355208-hpldjsc5	32	8	on	on	RB
cord-355208-hpldjsc5	32	9	were	be	VBD
cord-355208-hpldjsc5	32	10	indeed	indeed	RB
cord-355208-hpldjsc5	32	11	notable	notable	JJ
cord-355208-hpldjsc5	32	12	for	for	IN
cord-355208-hpldjsc5	32	13	lung	lung	NN
cord-355208-hpldjsc5	32	14	-	-	HYPH
cord-355208-hpldjsc5	32	15	vascular	vascular	JJ
cord-355208-hpldjsc5	32	16	congestion	congestion	NN
cord-355208-hpldjsc5	32	17	[	[	-LRB-
cord-355208-hpldjsc5	32	18	8	8	CD
cord-355208-hpldjsc5	32	19	]	]	-RRB-
cord-355208-hpldjsc5	32	20	.	.	.
cord-355208-hpldjsc5	33	1	Vascular	vascular	JJ
cord-355208-hpldjsc5	33	2	disease	disease	NN
cord-355208-hpldjsc5	33	3	may	may	MD
cord-355208-hpldjsc5	33	4	also	also	RB
cord-355208-hpldjsc5	33	5	explain	explain	VB
cord-355208-hpldjsc5	33	6	massive	massive	JJ
cord-355208-hpldjsc5	33	7	D	d	NN
cord-355208-hpldjsc5	33	8	-	-	HYPH
cord-355208-hpldjsc5	33	9	dimer	dimer	NN
cord-355208-hpldjsc5	33	10	elevations	elevation	NNS
cord-355208-hpldjsc5	33	11	,	,	,
cord-355208-hpldjsc5	33	12	while	while	IN
cord-355208-hpldjsc5	33	13	antiphospholipid	antiphospholipid	NNP
cord-355208-hpldjsc5	33	14	antibodies	antibody	NNS
cord-355208-hpldjsc5	33	15	were	be	VBD
cord-355208-hpldjsc5	33	16	recently	recently	RB
cord-355208-hpldjsc5	33	17	reported	report	VBN
cord-355208-hpldjsc5	33	18	in	in	IN
cord-355208-hpldjsc5	33	19	COVID-19	COVID-19	NNP
cord-355208-hpldjsc5	33	20	[	[	-LRB-
cord-355208-hpldjsc5	33	21	9	9	CD
cord-355208-hpldjsc5	33	22	]	]	-RRB-
cord-355208-hpldjsc5	33	23	.	.	.
cord-355208-hpldjsc5	34	1	A	a	DT
cord-355208-hpldjsc5	34	2	constellation	constellation	NN
cord-355208-hpldjsc5	34	3	of	of	IN
cord-355208-hpldjsc5	34	4	multi	multi	JJ
cord-355208-hpldjsc5	34	5	-	-	JJ
cord-355208-hpldjsc5	34	6	system	system	JJ
cord-355208-hpldjsc5	34	7	organ	organ	NN
cord-355208-hpldjsc5	34	8	involvement	involvement	NN
cord-355208-hpldjsc5	34	9	,	,	,
cord-355208-hpldjsc5	34	10	low	low	JJ
cord-355208-hpldjsc5	34	11	-	-	HYPH
cord-355208-hpldjsc5	34	12	grade	grade	NN
cord-355208-hpldjsc5	34	13	inflammation	inflammation	NN
cord-355208-hpldjsc5	34	14	,	,	,
cord-355208-hpldjsc5	34	15	lymphopenia	lymphopenia	NNP
cord-355208-hpldjsc5	34	16	,	,	,
cord-355208-hpldjsc5	34	17	hypercoagulability	hypercoagulability	NN
cord-355208-hpldjsc5	34	18	,	,	,
cord-355208-hpldjsc5	34	19	and	and	CC
cord-355208-hpldjsc5	34	20	heterogenous	heterogenous	JJ
cord-355208-hpldjsc5	34	21	microvascular	microvascular	JJ
cord-355208-hpldjsc5	34	22	dysfunction	dysfunction	NN
cord-355208-hpldjsc5	34	23	is	be	VBZ
cord-355208-hpldjsc5	34	24	a	a	DT
cord-355208-hpldjsc5	34	25	classic	classic	JJ
cord-355208-hpldjsc5	34	26	description	description	NN
cord-355208-hpldjsc5	34	27	of	of	IN
cord-355208-hpldjsc5	34	28	many	many	JJ
cord-355208-hpldjsc5	34	29	systemic	systemic	JJ
cord-355208-hpldjsc5	34	30	vasculopathies	vasculopathie	NNS
cord-355208-hpldjsc5	34	31	,	,	,
cord-355208-hpldjsc5	34	32	such	such	JJ
cord-355208-hpldjsc5	34	33	as	as	IN
cord-355208-hpldjsc5	34	34	vasculitides	vasculitide	NNS
cord-355208-hpldjsc5	34	35	(	(	-LRB-
cord-355208-hpldjsc5	34	36	Supplement	Supplement	NNP
cord-355208-hpldjsc5	34	37	Table	Table	NNP
cord-355208-hpldjsc5	34	38	)	)	-RRB-
cord-355208-hpldjsc5	34	39	.	.	.
cord-355208-hpldjsc5	35	1	Reported	report	VBN
cord-355208-hpldjsc5	35	2	findings	finding	NNS
cord-355208-hpldjsc5	35	3	indicate	indicate	VBP
cord-355208-hpldjsc5	35	4	that	that	IN
cord-355208-hpldjsc5	35	5	immunosuppression	immunosuppression	NN
cord-355208-hpldjsc5	35	6	,	,	,
cord-355208-hpldjsc5	35	7	endothelial	endothelial	JJ
cord-355208-hpldjsc5	35	8	activation	activation	NN
cord-355208-hpldjsc5	35	9	,	,	,
cord-355208-hpldjsc5	35	10	and	and	CC
cord-355208-hpldjsc5	35	11	direct	direct	JJ
cord-355208-hpldjsc5	35	12	viral	viral	RB
cord-355208-hpldjsc5	35	13	-	-	HYPH
cord-355208-hpldjsc5	35	14	mediated	mediate	VBN
cord-355208-hpldjsc5	35	15	tissue	tissue	NN
cord-355208-hpldjsc5	35	16	damage	damage	NN
cord-355208-hpldjsc5	35	17	,	,	,
cord-355208-hpldjsc5	35	18	rather	rather	RB
cord-355208-hpldjsc5	35	19	than	than	IN
cord-355208-hpldjsc5	35	20	hyperinflammatory	hyperinflammatory	JJ
cord-355208-hpldjsc5	35	21	injury	injury	NN
cord-355208-hpldjsc5	35	22	,	,	,
cord-355208-hpldjsc5	35	23	mediate	mediate	VB
cord-355208-hpldjsc5	35	24	COVID	COVID	NNP
cord-355208-hpldjsc5	35	25	-	-	HYPH
cord-355208-hpldjsc5	35	26	induced	induce	VBN
cord-355208-hpldjsc5	35	27	organ	organ	NN
cord-355208-hpldjsc5	35	28	dysfunction	dysfunction	NN
cord-355208-hpldjsc5	35	29	.	.	.
cord-355208-hpldjsc5	36	1	For	for	IN
cord-355208-hpldjsc5	36	2	example	example	NN
cord-355208-hpldjsc5	36	3	,	,	,
cord-355208-hpldjsc5	36	4	a	a	DT
cord-355208-hpldjsc5	36	5	recent	recent	JJ
cord-355208-hpldjsc5	36	6	autopsy	autopsy	JJ
cord-355208-hpldjsc5	36	7	study	study	NN
cord-355208-hpldjsc5	36	8	found	find	VBD
cord-355208-hpldjsc5	36	9	no	no	DT
cord-355208-hpldjsc5	36	10	renovascular	renovascular	JJ
cord-355208-hpldjsc5	36	11	or	or	CC
cord-355208-hpldjsc5	36	12	interstitial	interstitial	JJ
cord-355208-hpldjsc5	36	13	inflammation	inflammation	NN
cord-355208-hpldjsc5	36	14	,	,	,
cord-355208-hpldjsc5	36	15	but	but	CC
cord-355208-hpldjsc5	36	16	noted	note	VBD
cord-355208-hpldjsc5	36	17	endothelial	endothelial	JJ
cord-355208-hpldjsc5	36	18	activation	activation	NN
cord-355208-hpldjsc5	36	19	,	,	,
cord-355208-hpldjsc5	36	20	occasional	occasional	JJ
cord-355208-hpldjsc5	36	21	frank	frank	JJ
cord-355208-hpldjsc5	36	22	necrosis	necrosis	NN
cord-355208-hpldjsc5	36	23	,	,	,
cord-355208-hpldjsc5	36	24	and	and	CC
cord-355208-hpldjsc5	36	25	copious	copious	JJ
cord-355208-hpldjsc5	36	26	virions	virion	NNS
cord-355208-hpldjsc5	36	27	in	in	IN
cord-355208-hpldjsc5	36	28	renal	renal	JJ
cord-355208-hpldjsc5	36	29	tissue	tissue	NN
cord-355208-hpldjsc5	36	30	[	[	-LRB-
cord-355208-hpldjsc5	36	31	10	10	CD
cord-355208-hpldjsc5	36	32	]	]	-RRB-
cord-355208-hpldjsc5	36	33	.	.	.
cord-355208-hpldjsc5	37	1	If	if	IN
cord-355208-hpldjsc5	37	2	direct	direct	JJ
cord-355208-hpldjsc5	37	3	infection	infection	NN
cord-355208-hpldjsc5	37	4	drives	drive	VBZ
cord-355208-hpldjsc5	37	5	injury	injury	NN
cord-355208-hpldjsc5	37	6	,	,	,
cord-355208-hpldjsc5	37	7	vascular	vascular	JJ
cord-355208-hpldjsc5	37	8	tissue	tissue	NN
cord-355208-hpldjsc5	37	9	is	be	VBZ
cord-355208-hpldjsc5	37	10	expected	expect	VBN
cord-355208-hpldjsc5	37	11	to	to	TO
cord-355208-hpldjsc5	37	12	be	be	VB
cord-355208-hpldjsc5	37	13	quite	quite	RB
cord-355208-hpldjsc5	37	14	susceptible	susceptible	JJ
cord-355208-hpldjsc5	37	15	as	as	IN
cord-355208-hpldjsc5	37	16	it	-PRON-	PRP
cord-355208-hpldjsc5	37	17	highly	highly	RB
cord-355208-hpldjsc5	37	18	expresses	express	VBZ
cord-355208-hpldjsc5	37	19	angiotensin	angiotensin	NN
cord-355208-hpldjsc5	37	20	-	-	HYPH
cord-355208-hpldjsc5	37	21	converting	convert	VBG
cord-355208-hpldjsc5	37	22	enzyme-2	enzyme-2	NNP
cord-355208-hpldjsc5	37	23	(	(	-LRB-
cord-355208-hpldjsc5	37	24	ACE-2	ACE-2	NNP
cord-355208-hpldjsc5	37	25	)	)	-RRB-
cord-355208-hpldjsc5	37	26	,	,	,
cord-355208-hpldjsc5	37	27	which	which	WDT
cord-355208-hpldjsc5	37	28	is	be	VBZ
cord-355208-hpldjsc5	37	29	essential	essential	JJ
cord-355208-hpldjsc5	37	30	for	for	IN
cord-355208-hpldjsc5	37	31	coronavirus	coronavirus	NN
cord-355208-hpldjsc5	37	32	uptake	uptake	NN
cord-355208-hpldjsc5	37	33	.	.	.
cord-355208-hpldjsc5	38	1	SARS	SARS	NNP
cord-355208-hpldjsc5	38	2	-	-	HYPH
cord-355208-hpldjsc5	38	3	CoV-2	CoV-2	NNP
cord-355208-hpldjsc5	38	4	initiates	initiate	VBZ
cord-355208-hpldjsc5	38	5	cellular	cellular	JJ
cord-355208-hpldjsc5	38	6	infection	infection	NN
cord-355208-hpldjsc5	38	7	by	by	IN
cord-355208-hpldjsc5	38	8	binding	bind	VBG
cord-355208-hpldjsc5	38	9	ACE-2	ACE-2	NNP
cord-355208-hpldjsc5	38	10	on	on	IN
cord-355208-hpldjsc5	38	11	the	the	DT
cord-355208-hpldjsc5	38	12	surface	surface	NN
cord-355208-hpldjsc5	38	13	of	of	IN
cord-355208-hpldjsc5	38	14	human	human	JJ
cord-355208-hpldjsc5	38	15	cells	cell	NNS
cord-355208-hpldjsc5	38	16	,	,	,
cord-355208-hpldjsc5	38	17	including	include	VBG
cord-355208-hpldjsc5	38	18	endothelial	endothelial	JJ
cord-355208-hpldjsc5	38	19	cells	cell	NNS
cord-355208-hpldjsc5	38	20	(	(	-LRB-
cord-355208-hpldjsc5	38	21	Fig	fig	NN
cord-355208-hpldjsc5	38	22	.	.	.
cord-355208-hpldjsc5	38	23	1	1	CD
cord-355208-hpldjsc5	38	24	)	)	-RRB-
cord-355208-hpldjsc5	39	1	[	[	-LRB-
cord-355208-hpldjsc5	39	2	11	11	CD
cord-355208-hpldjsc5	39	3	]	]	-RRB-
cord-355208-hpldjsc5	39	4	.	.	.
cord-355208-hpldjsc5	40	1	Attachment	attachment	NN
cord-355208-hpldjsc5	40	2	promotes	promote	VBZ
cord-355208-hpldjsc5	40	3	disordered	disordered	JJ
cord-355208-hpldjsc5	40	4	cytokine	cytokine	JJ
cord-355208-hpldjsc5	40	5	paracrine	paracrine	NN
cord-355208-hpldjsc5	40	6	signaling	signaling	NN
cord-355208-hpldjsc5	40	7	,	,	,
cord-355208-hpldjsc5	40	8	including	include	VBG
cord-355208-hpldjsc5	40	9	both	both	CC
cord-355208-hpldjsc5	40	10	pro	pro	JJ
cord-355208-hpldjsc5	40	11	-	-	JJ
cord-355208-hpldjsc5	40	12	and	and	CC
cord-355208-hpldjsc5	40	13	anti	anti	JJ
cord-355208-hpldjsc5	40	14	-	-	JJ
cord-355208-hpldjsc5	40	15	inflammatory	inflammatory	JJ
cord-355208-hpldjsc5	40	16	molecules	molecule	NNS
cord-355208-hpldjsc5	40	17	,	,	,
cord-355208-hpldjsc5	40	18	and	and	CC
cord-355208-hpldjsc5	40	19	pro	pro	JJ
cord-355208-hpldjsc5	40	20	-	-	JJ
cord-355208-hpldjsc5	40	21	apoptotic	apoptotic	JJ
cord-355208-hpldjsc5	40	22	mediators	mediator	NNS
cord-355208-hpldjsc5	40	23	[	[	-LRB-
cord-355208-hpldjsc5	40	24	12	12	CD
cord-355208-hpldjsc5	40	25	]	]	-RRB-
cord-355208-hpldjsc5	40	26	.	.	.
cord-355208-hpldjsc5	41	1	Chemokine	Chemokine	NNP
cord-355208-hpldjsc5	41	2	-	-	HYPH
cord-355208-hpldjsc5	41	3	mediated	mediate	VBN
cord-355208-hpldjsc5	41	4	lymphocyte	lymphocyte	NN
cord-355208-hpldjsc5	41	5	recruitment	recruitment	NN
cord-355208-hpldjsc5	41	6	and	and	CC
cord-355208-hpldjsc5	41	7	subsequent	subsequent	JJ
cord-355208-hpldjsc5	41	8	infection	infection	NN
cord-355208-hpldjsc5	41	9	of	of	IN
cord-355208-hpldjsc5	41	10	lymphocytes	lymphocyte	NNS
cord-355208-hpldjsc5	41	11	,	,	,
cord-355208-hpldjsc5	41	12	which	which	WDT
cord-355208-hpldjsc5	41	13	also	also	RB
cord-355208-hpldjsc5	41	14	express	express	VBP
cord-355208-hpldjsc5	41	15	ACE-2	ACE-2	NNP
cord-355208-hpldjsc5	41	16	,	,	,
cord-355208-hpldjsc5	41	17	likely	likely	RB
cord-355208-hpldjsc5	41	18	contribute	contribute	VB
cord-355208-hpldjsc5	41	19	to	to	IN
cord-355208-hpldjsc5	41	20	lymphocyte	lymphocyte	NN
cord-355208-hpldjsc5	41	21	apoptosis	apoptosis	NN
cord-355208-hpldjsc5	41	22	,	,	,
cord-355208-hpldjsc5	41	23	natural	natural	JJ
cord-355208-hpldjsc5	41	24	killer	killer	NN
cord-355208-hpldjsc5	41	25	and	and	CC
cord-355208-hpldjsc5	41	26	B	b	NN
cord-355208-hpldjsc5	41	27	cell	cell	NN
cord-355208-hpldjsc5	41	28	suppression	suppression	NN
cord-355208-hpldjsc5	41	29	,	,	,
cord-355208-hpldjsc5	41	30	and	and	CC
cord-355208-hpldjsc5	41	31	T	t	NN
cord-355208-hpldjsc5	41	32	cell	cell	NN
cord-355208-hpldjsc5	41	33	exhaustion	exhaustion	NN
cord-355208-hpldjsc5	41	34	,	,	,
cord-355208-hpldjsc5	41	35	as	as	IN
cord-355208-hpldjsc5	41	36	noted	note	VBN
cord-355208-hpldjsc5	41	37	by	by	IN
cord-355208-hpldjsc5	41	38	Qin	Qin	NNP
cord-355208-hpldjsc5	41	39	et	et	FW
cord-355208-hpldjsc5	41	40	al	al	NNP
cord-355208-hpldjsc5	41	41	.	.	.
cord-355208-hpldjsc5	42	1	[	[	-LRB-
cord-355208-hpldjsc5	42	2	3	3	CD
cord-355208-hpldjsc5	42	3	]	]	-RRB-
cord-355208-hpldjsc5	42	4	.	.	.
cord-355208-hpldjsc5	43	1	These	these	DT
cord-355208-hpldjsc5	43	2	findings	finding	NNS
cord-355208-hpldjsc5	43	3	are	be	VBP
cord-355208-hpldjsc5	43	4	consistent	consistent	JJ
cord-355208-hpldjsc5	43	5	with	with	IN
cord-355208-hpldjsc5	43	6	clinical	clinical	JJ
cord-355208-hpldjsc5	43	7	lymphopenia	lymphopenia	NNP
cord-355208-hpldjsc5	43	8	,	,	,
cord-355208-hpldjsc5	43	9	which	which	WDT
cord-355208-hpldjsc5	43	10	correlates	correlate	VBZ
cord-355208-hpldjsc5	43	11	with	with	IN
cord-355208-hpldjsc5	43	12	mortality	mortality	NN
cord-355208-hpldjsc5	43	13	[	[	-LRB-
cord-355208-hpldjsc5	43	14	3	3	CD
cord-355208-hpldjsc5	43	15	]	]	-RRB-
cord-355208-hpldjsc5	43	16	.	.	.
cord-355208-hpldjsc5	44	1	Viral	viral	JJ
cord-355208-hpldjsc5	44	2	injury	injury	NN
cord-355208-hpldjsc5	44	3	,	,	,
cord-355208-hpldjsc5	44	4	disordered	disordered	JJ
cord-355208-hpldjsc5	44	5	cytokine	cytokine	NN
cord-355208-hpldjsc5	44	6	release	release	NN
cord-355208-hpldjsc5	44	7	,	,	,
cord-355208-hpldjsc5	44	8	and	and	CC
cord-355208-hpldjsc5	44	9	damage	damage	NN
cord-355208-hpldjsc5	44	10	-	-	HYPH
cord-355208-hpldjsc5	44	11	associated	associate	VBN
cord-355208-hpldjsc5	44	12	Fig	Fig	NNP
cord-355208-hpldjsc5	44	13	.	.	.
cord-355208-hpldjsc5	44	14	1	1	CD
cord-355208-hpldjsc5	44	15	(	(	-LRB-
cord-355208-hpldjsc5	44	16	1	1	CD
cord-355208-hpldjsc5	44	17	)	)	-RRB-
cord-355208-hpldjsc5	45	1	The	the	DT
cord-355208-hpldjsc5	45	2	SARS	SARS	NNP
cord-355208-hpldjsc5	45	3	-	-	HYPH
cord-355208-hpldjsc5	45	4	CoV-2	CoV-2	NNP
cord-355208-hpldjsc5	45	5	virus	virus	NN
cord-355208-hpldjsc5	45	6	infects	infect	VBZ
cord-355208-hpldjsc5	45	7	an	an	DT
cord-355208-hpldjsc5	45	8	endothelial	endothelial	JJ
cord-355208-hpldjsc5	45	9	cell	cell	NN
cord-355208-hpldjsc5	45	10	by	by	IN
cord-355208-hpldjsc5	45	11	binding	bind	VBG
cord-355208-hpldjsc5	45	12	to	to	IN
cord-355208-hpldjsc5	45	13	ACE-2	ACE-2	NNP
cord-355208-hpldjsc5	45	14	.	.	.
cord-355208-hpldjsc5	46	1	Cellular	cellular	JJ
cord-355208-hpldjsc5	46	2	infection	infection	NN
cord-355208-hpldjsc5	46	3	initiates	initiate	VBZ
cord-355208-hpldjsc5	46	4	localized	localize	VBN
cord-355208-hpldjsc5	46	5	inflammation	inflammation	NN
cord-355208-hpldjsc5	46	6	,	,	,
cord-355208-hpldjsc5	46	7	endothelial	endothelial	JJ
cord-355208-hpldjsc5	46	8	activation	activation	NN
cord-355208-hpldjsc5	46	9	,	,	,
cord-355208-hpldjsc5	46	10	tissue	tissue	NN
cord-355208-hpldjsc5	46	11	damage	damage	NN
cord-355208-hpldjsc5	46	12	,	,	,
cord-355208-hpldjsc5	46	13	and	and	CC
cord-355208-hpldjsc5	46	14	disordered	disordered	JJ
cord-355208-hpldjsc5	46	15	cytokine	cytokine	NN
cord-355208-hpldjsc5	46	16	release	release	NN
cord-355208-hpldjsc5	46	17	.	.	.
cord-355208-hpldjsc5	47	1	Membrane	membrane	NN
cord-355208-hpldjsc5	47	2	fusion	fusion	NN
cord-355208-hpldjsc5	47	3	also	also	RB
cord-355208-hpldjsc5	47	4	interrupts	interrupt	VBZ
cord-355208-hpldjsc5	47	5	AngII	AngII	NNP
cord-355208-hpldjsc5	47	6	metabolism	metabolism	NN
cord-355208-hpldjsc5	47	7	,	,	,
cord-355208-hpldjsc5	47	8	leading	lead	VBG
cord-355208-hpldjsc5	47	9	to	to	IN
cord-355208-hpldjsc5	47	10	an	an	DT
cord-355208-hpldjsc5	47	11	increase	increase	NN
cord-355208-hpldjsc5	47	12	in	in	IN
cord-355208-hpldjsc5	47	13	AngII	AngII	NNP
cord-355208-hpldjsc5	47	14	and	and	CC
cord-355208-hpldjsc5	47	15	a	a	DT
cord-355208-hpldjsc5	47	16	decrease	decrease	NN
cord-355208-hpldjsc5	47	17	in	in	IN
cord-355208-hpldjsc5	47	18	Ang	Ang	NNP
cord-355208-hpldjsc5	47	19	(	(	-LRB-
cord-355208-hpldjsc5	47	20	1	1	CD
cord-355208-hpldjsc5	47	21	-	-	SYM
cord-355208-hpldjsc5	47	22	7	7	CD
cord-355208-hpldjsc5	47	23	)	)	-RRB-
cord-355208-hpldjsc5	47	24	,	,	,
cord-355208-hpldjsc5	47	25	augmenting	augment	VBG
cord-355208-hpldjsc5	47	26	inflammation	inflammation	NN
cord-355208-hpldjsc5	47	27	,	,	,
cord-355208-hpldjsc5	47	28	endothelial	endothelial	JJ
cord-355208-hpldjsc5	47	29	activation	activation	NN
cord-355208-hpldjsc5	47	30	,	,	,
cord-355208-hpldjsc5	47	31	and	and	CC
cord-355208-hpldjsc5	47	32	leukocyte	leukocyte	NN
cord-355208-hpldjsc5	47	33	and	and	CC
cord-355208-hpldjsc5	47	34	platelet	platelet	NN
cord-355208-hpldjsc5	47	35	recruitment	recruitment	NN
cord-355208-hpldjsc5	47	36	.	.	.
cord-355208-hpldjsc5	48	1	(	(	-LRB-
cord-355208-hpldjsc5	48	2	2	2	LS
cord-355208-hpldjsc5	48	3	)	)	-RRB-
cord-355208-hpldjsc5	48	4	Pulmonary	pulmonary	JJ
cord-355208-hpldjsc5	48	5	endothelial	endothelial	JJ
cord-355208-hpldjsc5	48	6	activation	activation	NN
cord-355208-hpldjsc5	48	7	leads	lead	VBZ
cord-355208-hpldjsc5	48	8	to	to	IN
cord-355208-hpldjsc5	48	9	the	the	DT
cord-355208-hpldjsc5	48	10	ACE-1	ACE-1	NNP
cord-355208-hpldjsc5	48	11	shedding	shedding	NN
cord-355208-hpldjsc5	48	12	phenomenon	phenomenon	NN
cord-355208-hpldjsc5	48	13	,	,	,
cord-355208-hpldjsc5	48	14	where	where	WRB
cord-355208-hpldjsc5	48	15	ACE-1	ACE-1	NNP
cord-355208-hpldjsc5	48	16	is	be	VBZ
cord-355208-hpldjsc5	48	17	rapidly	rapidly	RB
cord-355208-hpldjsc5	48	18	liberated	liberate	VBN
cord-355208-hpldjsc5	48	19	from	from	IN
cord-355208-hpldjsc5	48	20	the	the	DT
cord-355208-hpldjsc5	48	21	cell	cell	NN
cord-355208-hpldjsc5	48	22	membrane	membrane	NN
cord-355208-hpldjsc5	48	23	.	.	.
cord-355208-hpldjsc5	49	1	This	this	DT
cord-355208-hpldjsc5	49	2	produces	produce	VBZ
cord-355208-hpldjsc5	49	3	an	an	DT
cord-355208-hpldjsc5	49	4	initial	initial	JJ
cord-355208-hpldjsc5	49	5	rapid	rapid	JJ
cord-355208-hpldjsc5	49	6	rise	rise	NN
cord-355208-hpldjsc5	49	7	in	in	IN
cord-355208-hpldjsc5	49	8	AngII	AngII	NNP
cord-355208-hpldjsc5	49	9	,	,	,
cord-355208-hpldjsc5	49	10	which	which	WDT
cord-355208-hpldjsc5	49	11	can	can	MD
cord-355208-hpldjsc5	49	12	induce	induce	VB
cord-355208-hpldjsc5	49	13	a	a	DT
cord-355208-hpldjsc5	49	14	positive	positive	JJ
cord-355208-hpldjsc5	49	15	feedback	feedback	NN
cord-355208-hpldjsc5	49	16	loop	loop	NN
cord-355208-hpldjsc5	49	17	enhancing	enhance	VBG
cord-355208-hpldjsc5	49	18	local	local	JJ
cord-355208-hpldjsc5	49	19	inflammation	inflammation	NN
cord-355208-hpldjsc5	49	20	,	,	,
cord-355208-hpldjsc5	49	21	coagulation	coagulation	NN
cord-355208-hpldjsc5	49	22	,	,	,
cord-355208-hpldjsc5	49	23	and	and	CC
cord-355208-hpldjsc5	49	24	capillary	capillary	JJ
cord-355208-hpldjsc5	49	25	leak	leak	NN
cord-355208-hpldjsc5	49	26	.	.	.
cord-355208-hpldjsc5	50	1	(	(	-LRB-
cord-355208-hpldjsc5	50	2	3	3	LS
cord-355208-hpldjsc5	50	3	)	)	-RRB-
cord-355208-hpldjsc5	51	1	The	the	DT
cord-355208-hpldjsc5	51	2	transiently	transiently	RB
cord-355208-hpldjsc5	51	3	increased	increase	VBN
cord-355208-hpldjsc5	51	4	ACE-1	ACE-1	NNP
cord-355208-hpldjsc5	51	5	dissipates	dissipate	VBZ
cord-355208-hpldjsc5	51	6	,	,	,
cord-355208-hpldjsc5	51	7	leading	lead	VBG
cord-355208-hpldjsc5	51	8	to	to	IN
cord-355208-hpldjsc5	51	9	subphysiologic	subphysiologic	VB
cord-355208-hpldjsc5	51	10	AngII	AngII	NNP
cord-355208-hpldjsc5	51	11	concentrations	concentration	NNS
cord-355208-hpldjsc5	51	12	.	.	.
cord-355208-hpldjsc5	52	1	Low	low	JJ
cord-355208-hpldjsc5	52	2	AngII	AngII	NNP
cord-355208-hpldjsc5	52	3	in	in	IN
cord-355208-hpldjsc5	52	4	this	this	DT
cord-355208-hpldjsc5	52	5	phase	phase	NN
cord-355208-hpldjsc5	52	6	leads	lead	VBZ
cord-355208-hpldjsc5	52	7	to	to	IN
cord-355208-hpldjsc5	52	8	vasodilation	vasodilation	NN
cord-355208-hpldjsc5	52	9	,	,	,
cord-355208-hpldjsc5	52	10	worsened	worsen	VBD
cord-355208-hpldjsc5	52	11	capillary	capillary	JJ
cord-355208-hpldjsc5	52	12	leak	leak	NN
cord-355208-hpldjsc5	52	13	,	,	,
cord-355208-hpldjsc5	52	14	and	and	CC
cord-355208-hpldjsc5	52	15	impaired	impair	VBD
cord-355208-hpldjsc5	52	16	endothelial	endothelial	JJ
cord-355208-hpldjsc5	52	17	conductance	conductance	NN
cord-355208-hpldjsc5	52	18	and	and	CC
cord-355208-hpldjsc5	52	19	autoregulation	autoregulation	NN
cord-355208-hpldjsc5	52	20	.	.	.
cord-355208-hpldjsc5	53	1	Low	low	JJ
cord-355208-hpldjsc5	53	2	systemic	systemic	JJ
cord-355208-hpldjsc5	53	3	AngII	AngII	NNP
cord-355208-hpldjsc5	53	4	also	also	RB
cord-355208-hpldjsc5	53	5	upregulates	upregulate	VBZ
cord-355208-hpldjsc5	53	6	ACE-2	ACE-2	NNP
cord-355208-hpldjsc5	53	7	,	,	,
cord-355208-hpldjsc5	53	8	possibly	possibly	RB
cord-355208-hpldjsc5	53	9	increasing	increase	VBG
cord-355208-hpldjsc5	53	10	susceptibility	susceptibility	NN
cord-355208-hpldjsc5	53	11	to	to	IN
cord-355208-hpldjsc5	53	12	SARS	SARS	NNP
cord-355208-hpldjsc5	53	13	-	-	HYPH
cord-355208-hpldjsc5	53	14	CoV-2	CoV-2	NNP
cord-355208-hpldjsc5	53	15	in	in	IN
cord-355208-hpldjsc5	53	16	remote	remote	JJ
cord-355208-hpldjsc5	53	17	tissue	tissue	NN
cord-355208-hpldjsc5	53	18	.	.	.
cord-355208-hpldjsc5	54	1	ACE	ace	NN
cord-355208-hpldjsc5	54	2	,	,	,
cord-355208-hpldjsc5	54	3	angiotensin	angiotensin	NN
cord-355208-hpldjsc5	54	4	-	-	HYPH
cord-355208-hpldjsc5	54	5	converting	convert	VBG
cord-355208-hpldjsc5	54	6	enzyme	enzyme	NN
cord-355208-hpldjsc5	54	7	;	;	:
cord-355208-hpldjsc5	54	8	AngI	AngI	NNP
cord-355208-hpldjsc5	54	9	,	,	,
cord-355208-hpldjsc5	54	10	angiotensin	angiotensin	NN
cord-355208-hpldjsc5	54	11	-	-	HYPH
cord-355208-hpldjsc5	54	12	I	i	NN
cord-355208-hpldjsc5	54	13	;	;	:
cord-355208-hpldjsc5	54	14	AngII	AngII	NNP
cord-355208-hpldjsc5	54	15	,	,	,
cord-355208-hpldjsc5	54	16	angiotensin	angiotensin	NN
cord-355208-hpldjsc5	54	17	-	-	HYPH
cord-355208-hpldjsc5	54	18	II	II	NNP
cord-355208-hpldjsc5	54	19	;	;	:
cord-355208-hpldjsc5	54	20	Ang	Ang	NNP
cord-355208-hpldjsc5	54	21	(	(	-LRB-
cord-355208-hpldjsc5	54	22	1	1	CD
cord-355208-hpldjsc5	54	23	-	-	SYM
cord-355208-hpldjsc5	54	24	7	7	CD
cord-355208-hpldjsc5	54	25	)	)	-RRB-
cord-355208-hpldjsc5	54	26	,	,	,
cord-355208-hpldjsc5	54	27	angiotensin	angiotensin	NN
cord-355208-hpldjsc5	54	28	(	(	-LRB-
cord-355208-hpldjsc5	54	29	1	1	CD
cord-355208-hpldjsc5	54	30	-	-	SYM
cord-355208-hpldjsc5	54	31	7	7	CD
cord-355208-hpldjsc5	54	32	)	)	-RRB-
cord-355208-hpldjsc5	54	33	;	;	:
cord-355208-hpldjsc5	54	34	DAMPs	damp	NNS
cord-355208-hpldjsc5	54	35	,	,	,
cord-355208-hpldjsc5	54	36	damage	damage	NN
cord-355208-hpldjsc5	54	37	-	-	HYPH
cord-355208-hpldjsc5	54	38	associated	associate	VBN
cord-355208-hpldjsc5	54	39	molecular	molecular	JJ
cord-355208-hpldjsc5	54	40	pattern	pattern	NN
cord-355208-hpldjsc5	54	41	molecules	molecule	NNS
cord-355208-hpldjsc5	54	42	molecular	molecular	JJ
cord-355208-hpldjsc5	54	43	patterns	pattern	NNS
cord-355208-hpldjsc5	54	44	(	(	-LRB-
cord-355208-hpldjsc5	54	45	DAMPs	damp	NNS
cord-355208-hpldjsc5	54	46	)	)	-RRB-
cord-355208-hpldjsc5	54	47	induce	induce	VB
cord-355208-hpldjsc5	54	48	localized	localize	VBN
cord-355208-hpldjsc5	54	49	microvascular	microvascular	JJ
cord-355208-hpldjsc5	54	50	inflammation	inflammation	NN
cord-355208-hpldjsc5	54	51	,	,	,
cord-355208-hpldjsc5	54	52	which	which	WDT
cord-355208-hpldjsc5	54	53	triggers	trigger	VBZ
cord-355208-hpldjsc5	54	54	endothelial	endothelial	JJ
cord-355208-hpldjsc5	54	55	activation	activation	NN
cord-355208-hpldjsc5	54	56	,	,	,
cord-355208-hpldjsc5	54	57	leading	lead	VBG
cord-355208-hpldjsc5	54	58	to	to	IN
cord-355208-hpldjsc5	54	59	vasodilation	vasodilation	NN
cord-355208-hpldjsc5	54	60	and	and	CC
cord-355208-hpldjsc5	54	61	pro	pro	JJ
cord-355208-hpldjsc5	54	62	-	-	JJ
cord-355208-hpldjsc5	54	63	thrombotic	thrombotic	JJ
cord-355208-hpldjsc5	54	64	conditions	condition	NNS
cord-355208-hpldjsc5	54	65	.	.	.
cord-355208-hpldjsc5	55	1	Angiotensin	Angiotensin	NNP
cord-355208-hpldjsc5	55	2	-	-	HYPH
cord-355208-hpldjsc5	55	3	II	II	NNP
cord-355208-hpldjsc5	55	4	(	(	-LRB-
cord-355208-hpldjsc5	55	5	AngII	AngII	NNP
cord-355208-hpldjsc5	55	6	)	)	-RRB-
cord-355208-hpldjsc5	55	7	is	be	VBZ
cord-355208-hpldjsc5	55	8	primarily	primarily	RB
cord-355208-hpldjsc5	55	9	metabolized	metabolize	VBN
cord-355208-hpldjsc5	55	10	by	by	IN
cord-355208-hpldjsc5	55	11	endothelial	endothelial	JJ
cord-355208-hpldjsc5	55	12	ACE-2	ACE-2	NNP
cord-355208-hpldjsc5	55	13	to	to	IN
cord-355208-hpldjsc5	55	14	the	the	DT
cord-355208-hpldjsc5	55	15	vasodilatory	vasodilatory	NN
cord-355208-hpldjsc5	55	16	and	and	CC
cord-355208-hpldjsc5	55	17	anti	anti	JJ
cord-355208-hpldjsc5	55	18	-	-	JJ
cord-355208-hpldjsc5	55	19	inflammatory	inflammatory	JJ
cord-355208-hpldjsc5	55	20	peptide	peptide	NN
cord-355208-hpldjsc5	55	21	angiotensin	angiotensin	NN
cord-355208-hpldjsc5	55	22	(	(	-LRB-
cord-355208-hpldjsc5	55	23	1	1	CD
cord-355208-hpldjsc5	55	24	-	-	SYM
cord-355208-hpldjsc5	55	25	7	7	CD
cord-355208-hpldjsc5	55	26	)	)	-RRB-
cord-355208-hpldjsc5	55	27	.	.	.
cord-355208-hpldjsc5	56	1	In	in	IN
cord-355208-hpldjsc5	56	2	the	the	DT
cord-355208-hpldjsc5	56	3	early	early	JJ
cord-355208-hpldjsc5	56	4	phases	phase	NNS
cord-355208-hpldjsc5	56	5	of	of	IN
cord-355208-hpldjsc5	56	6	infection	infection	NN
cord-355208-hpldjsc5	56	7	,	,	,
cord-355208-hpldjsc5	56	8	ACE-2	ACE-2	NNP
cord-355208-hpldjsc5	56	9	consumption	consumption	NN
cord-355208-hpldjsc5	56	10	by	by	IN
cord-355208-hpldjsc5	56	11	viral	viral	JJ
cord-355208-hpldjsc5	56	12	entry	entry	NN
cord-355208-hpldjsc5	56	13	would	would	MD
cord-355208-hpldjsc5	56	14	be	be	VB
cord-355208-hpldjsc5	56	15	predicted	predict	VBN
cord-355208-hpldjsc5	56	16	to	to	TO
cord-355208-hpldjsc5	56	17	increase	increase	VB
cord-355208-hpldjsc5	56	18	local	local	JJ
cord-355208-hpldjsc5	56	19	AngII	AngII	NNP
cord-355208-hpldjsc5	56	20	concentration	concentration	NN
cord-355208-hpldjsc5	56	21	.	.	.
cord-355208-hpldjsc5	57	1	Among	among	IN
cord-355208-hpldjsc5	57	2	the	the	DT
cord-355208-hpldjsc5	57	3	known	know	VBN
cord-355208-hpldjsc5	57	4	effects	effect	NNS
cord-355208-hpldjsc5	57	5	of	of	IN
cord-355208-hpldjsc5	57	6	AngII	AngII	NNS
cord-355208-hpldjsc5	57	7	are	be	VBP
cord-355208-hpldjsc5	57	8	vasoconstriction	vasoconstriction	NN
cord-355208-hpldjsc5	57	9	,	,	,
cord-355208-hpldjsc5	57	10	endothelial	endothelial	JJ
cord-355208-hpldjsc5	57	11	activation	activation	NN
cord-355208-hpldjsc5	57	12	,	,	,
cord-355208-hpldjsc5	57	13	and	and	CC
cord-355208-hpldjsc5	57	14	pro	pro	JJ
cord-355208-hpldjsc5	57	15	-	-	JJ
cord-355208-hpldjsc5	57	16	inflammatory	inflammatory	JJ
cord-355208-hpldjsc5	57	17	cytokine	cytokine	NN
cord-355208-hpldjsc5	57	18	release	release	NN
cord-355208-hpldjsc5	57	19	.	.	.
cord-355208-hpldjsc5	58	1	Platelet	platelet	NN
cord-355208-hpldjsc5	58	2	activation	activation	NN
cord-355208-hpldjsc5	58	3	by	by	IN
cord-355208-hpldjsc5	58	4	AngII	AngII	NNP
cord-355208-hpldjsc5	58	5	may	may	MD
cord-355208-hpldjsc5	58	6	further	further	RB
cord-355208-hpldjsc5	58	7	enhance	enhance	VB
cord-355208-hpldjsc5	58	8	a	a	DT
cord-355208-hpldjsc5	58	9	pro	pro	JJ
cord-355208-hpldjsc5	58	10	-	-	JJ
cord-355208-hpldjsc5	58	11	thrombotic	thrombotic	JJ
cord-355208-hpldjsc5	58	12	milieu	milieu	NN
cord-355208-hpldjsc5	58	13	.	.	.
cord-355208-hpldjsc5	59	1	AngII	AngII	NNP
cord-355208-hpldjsc5	59	2	also	also	RB
cord-355208-hpldjsc5	59	3	has	have	VBZ
cord-355208-hpldjsc5	59	4	potent	potent	JJ
cord-355208-hpldjsc5	59	5	chemotactic	chemotactic	JJ
cord-355208-hpldjsc5	59	6	effects	effect	NNS
cord-355208-hpldjsc5	59	7	that	that	WDT
cord-355208-hpldjsc5	59	8	may	may	MD
cord-355208-hpldjsc5	59	9	accelerate	accelerate	VB
cord-355208-hpldjsc5	59	10	lymphocyte	lymphocyte	NN
cord-355208-hpldjsc5	59	11	recruitment	recruitment	NN
cord-355208-hpldjsc5	59	12	and	and	CC
cord-355208-hpldjsc5	59	13	suppression	suppression	NN
cord-355208-hpldjsc5	59	14	.	.	.
cord-355208-hpldjsc5	60	1	Importantly	importantly	RB
cord-355208-hpldjsc5	60	2	,	,	,
cord-355208-hpldjsc5	60	3	admission	admission	NN
cord-355208-hpldjsc5	60	4	AngII	AngII	NNP
cord-355208-hpldjsc5	60	5	levels	level	NNS
cord-355208-hpldjsc5	60	6	in	in	IN
cord-355208-hpldjsc5	61	1	COVID-19	covid-19	JJ
cord-355208-hpldjsc5	61	2	patients	patient	NNS
cord-355208-hpldjsc5	61	3	are	be	VBP
cord-355208-hpldjsc5	61	4	reportedly	reportedly	RB
cord-355208-hpldjsc5	61	5	twice	twice	PDT
cord-355208-hpldjsc5	61	6	the	the	DT
cord-355208-hpldjsc5	61	7	normal	normal	JJ
cord-355208-hpldjsc5	61	8	levels	level	NNS
cord-355208-hpldjsc5	61	9	[	[	-LRB-
cord-355208-hpldjsc5	61	10	13	13	CD
cord-355208-hpldjsc5	61	11	]	]	-RRB-
cord-355208-hpldjsc5	61	12	.	.	.
cord-355208-hpldjsc5	62	1	In	in	IN
cord-355208-hpldjsc5	62	2	addition	addition	NN
cord-355208-hpldjsc5	62	3	,	,	,
cord-355208-hpldjsc5	62	4	pulmonary	pulmonary	JJ
cord-355208-hpldjsc5	62	5	vascular	vascular	JJ
cord-355208-hpldjsc5	62	6	inflammation	inflammation	NN
cord-355208-hpldjsc5	62	7	specifically	specifically	RB
cord-355208-hpldjsc5	62	8	leads	lead	VBZ
cord-355208-hpldjsc5	62	9	to	to	IN
cord-355208-hpldjsc5	62	10	a	a	DT
cord-355208-hpldjsc5	62	11	phenomenon	phenomenon	NN
cord-355208-hpldjsc5	62	12	known	know	VBN
cord-355208-hpldjsc5	62	13	as	as	IN
cord-355208-hpldjsc5	62	14	ACE-1	ACE-1	NNP
cord-355208-hpldjsc5	62	15	"	"	``
cord-355208-hpldjsc5	62	16	shedding	shed	VBG
cord-355208-hpldjsc5	62	17	,	,	,
cord-355208-hpldjsc5	62	18	"	"	''
cord-355208-hpldjsc5	62	19	where	where	WRB
cord-355208-hpldjsc5	62	20	endothelial	endothelial	JJ
cord-355208-hpldjsc5	62	21	surface	surface	NN
cord-355208-hpldjsc5	62	22	-	-	HYPH
cord-355208-hpldjsc5	62	23	bound	bind	VBN
cord-355208-hpldjsc5	62	24	ACE-1	ACE-1	NNP
cord-355208-hpldjsc5	62	25	is	be	VBZ
cord-355208-hpldjsc5	62	26	released	release	VBN
cord-355208-hpldjsc5	62	27	into	into	IN
cord-355208-hpldjsc5	62	28	the	the	DT
cord-355208-hpldjsc5	62	29	interstitium	interstitium	NN
cord-355208-hpldjsc5	62	30	[	[	-LRB-
cord-355208-hpldjsc5	62	31	14	14	CD
cord-355208-hpldjsc5	62	32	]	]	-RRB-
cord-355208-hpldjsc5	62	33	.	.	.
cord-355208-hpldjsc5	63	1	This	this	DT
cord-355208-hpldjsc5	63	2	phenomenon	phenomenon	NN
cord-355208-hpldjsc5	63	3	initially	initially	RB
cord-355208-hpldjsc5	63	4	produces	produce	VBZ
cord-355208-hpldjsc5	63	5	a	a	DT
cord-355208-hpldjsc5	63	6	sharp	sharp	JJ
cord-355208-hpldjsc5	63	7	increase	increase	NN
cord-355208-hpldjsc5	63	8	in	in	IN
cord-355208-hpldjsc5	63	9	local	local	JJ
cord-355208-hpldjsc5	63	10	AngII	AngII	NNP
cord-355208-hpldjsc5	63	11	that	that	WDT
cord-355208-hpldjsc5	63	12	gradually	gradually	RB
cord-355208-hpldjsc5	63	13	decreases	decrease	VBZ
cord-355208-hpldjsc5	63	14	until	until	IN
cord-355208-hpldjsc5	63	15	concentrations	concentration	NNS
cord-355208-hpldjsc5	63	16	are	be	VBP
cord-355208-hpldjsc5	63	17	well	well	RB
cord-355208-hpldjsc5	63	18	below	below	IN
cord-355208-hpldjsc5	63	19	physiologic	physiologic	JJ
cord-355208-hpldjsc5	63	20	levels	level	NNS
cord-355208-hpldjsc5	63	21	[	[	-LRB-
cord-355208-hpldjsc5	63	22	14	14	CD
cord-355208-hpldjsc5	63	23	]	]	-RRB-
cord-355208-hpldjsc5	63	24	.	.	.
cord-355208-hpldjsc5	64	1	Because	because	IN
cord-355208-hpldjsc5	64	2	AngII	AngII	NNP
cord-355208-hpldjsc5	64	3	downregulates	downregulate	VBZ
cord-355208-hpldjsc5	64	4	ACE-2	ACE-2	NNP
cord-355208-hpldjsc5	64	5	expression	expression	NN
cord-355208-hpldjsc5	64	6	,	,	,
cord-355208-hpldjsc5	64	7	transition	transition	NN
cord-355208-hpldjsc5	64	8	to	to	IN
cord-355208-hpldjsc5	64	9	a	a	DT
cord-355208-hpldjsc5	64	10	state	state	NN
cord-355208-hpldjsc5	64	11	of	of	IN
cord-355208-hpldjsc5	64	12	AngII	AngII	NNP
cord-355208-hpldjsc5	64	13	deficiency	deficiency	NN
cord-355208-hpldjsc5	64	14	is	be	VBZ
cord-355208-hpldjsc5	64	15	consistent	consistent	JJ
cord-355208-hpldjsc5	64	16	with	with	IN
cord-355208-hpldjsc5	64	17	the	the	DT
cord-355208-hpldjsc5	64	18	increased	increase	VBN
cord-355208-hpldjsc5	64	19	ACE-2	ACE-2	NNP
cord-355208-hpldjsc5	64	20	expression	expression	NN
cord-355208-hpldjsc5	64	21	noted	note	VBN
cord-355208-hpldjsc5	64	22	at	at	IN
cord-355208-hpldjsc5	64	23	autopsy	autopsy	JJ
cord-355208-hpldjsc5	64	24	[	[	-LRB-
cord-355208-hpldjsc5	64	25	10	10	CD
cord-355208-hpldjsc5	64	26	]	]	-RRB-
cord-355208-hpldjsc5	64	27	.	.	.
cord-355208-hpldjsc5	65	1	Of	of	IN
cord-355208-hpldjsc5	65	2	note	note	NN
cord-355208-hpldjsc5	65	3	,	,	,
cord-355208-hpldjsc5	65	4	AngII	AngII	NNP
cord-355208-hpldjsc5	65	5	reportedly	reportedly	RB
cord-355208-hpldjsc5	65	6	increases	increase	VBZ
cord-355208-hpldjsc5	65	7	microvascular	microvascular	JJ
cord-355208-hpldjsc5	65	8	permeability	permeability	NN
cord-355208-hpldjsc5	65	9	under	under	IN
cord-355208-hpldjsc5	65	10	basal	basal	NN
cord-355208-hpldjsc5	65	11	conditions	condition	NNS
cord-355208-hpldjsc5	65	12	but	but	CC
cord-355208-hpldjsc5	65	13	decreases	decrease	VBZ
cord-355208-hpldjsc5	65	14	permeability	permeability	NN
cord-355208-hpldjsc5	65	15	during	during	IN
cord-355208-hpldjsc5	65	16	inflammation	inflammation	NN
cord-355208-hpldjsc5	65	17	,	,	,
cord-355208-hpldjsc5	65	18	an	an	DT
cord-355208-hpldjsc5	65	19	effect	effect	NN
cord-355208-hpldjsc5	65	20	attributed	attribute	VBN
cord-355208-hpldjsc5	65	21	to	to	IN
cord-355208-hpldjsc5	65	22	the	the	DT
cord-355208-hpldjsc5	65	23	inflammation	inflammation	NN
cord-355208-hpldjsc5	65	24	-	-	HYPH
cord-355208-hpldjsc5	65	25	induced	induce	VBN
cord-355208-hpldjsc5	65	26	shift	shift	NN
cord-355208-hpldjsc5	65	27	from	from	IN
cord-355208-hpldjsc5	65	28	type-1	type-1	NN
cord-355208-hpldjsc5	65	29	to	to	IN
cord-355208-hpldjsc5	65	30	type-2	type-2	NN
cord-355208-hpldjsc5	65	31	receptor	receptor	NN
cord-355208-hpldjsc5	65	32	expression	expression	NN
cord-355208-hpldjsc5	65	33	[	[	-LRB-
cord-355208-hpldjsc5	65	34	15	15	CD
cord-355208-hpldjsc5	65	35	]	]	-RRB-
cord-355208-hpldjsc5	65	36	.	.	.
cord-355208-hpldjsc5	66	1	Postulating	postulate	VBG
cord-355208-hpldjsc5	66	2	that	that	IN
cord-355208-hpldjsc5	66	3	COVID-19	COVID-19	NNP
cord-355208-hpldjsc5	66	4	is	be	VBZ
cord-355208-hpldjsc5	66	5	a	a	DT
cord-355208-hpldjsc5	66	6	vascular	vascular	JJ
cord-355208-hpldjsc5	66	7	and	and	CC
cord-355208-hpldjsc5	66	8	hypoinflammatory	hypoinflammatory	JJ
cord-355208-hpldjsc5	66	9	disease	disease	NN
cord-355208-hpldjsc5	66	10	has	have	VBZ
cord-355208-hpldjsc5	66	11	important	important	JJ
cord-355208-hpldjsc5	66	12	implications	implication	NNS
cord-355208-hpldjsc5	66	13	for	for	IN
cord-355208-hpldjsc5	66	14	ongoing	ongoing	JJ
cord-355208-hpldjsc5	66	15	research	research	NN
cord-355208-hpldjsc5	66	16	.	.	.
cord-355208-hpldjsc5	67	1	However	however	RB
cord-355208-hpldjsc5	67	2	,	,	,
cord-355208-hpldjsc5	67	3	more	more	JJR
cord-355208-hpldjsc5	67	4	evidence	evidence	NN
cord-355208-hpldjsc5	67	5	is	be	VBZ
cord-355208-hpldjsc5	67	6	needed	need	VBN
cord-355208-hpldjsc5	67	7	to	to	TO
cord-355208-hpldjsc5	67	8	explore	explore	VB
cord-355208-hpldjsc5	67	9	vascular	vascular	JJ
cord-355208-hpldjsc5	67	10	injury	injury	NN
cord-355208-hpldjsc5	67	11	through	through	IN
cord-355208-hpldjsc5	67	12	biomarkers	biomarker	NNS
cord-355208-hpldjsc5	67	13	,	,	,
cord-355208-hpldjsc5	67	14	imaging	imaging	NN
cord-355208-hpldjsc5	67	15	,	,	,
cord-355208-hpldjsc5	67	16	and	and	CC
cord-355208-hpldjsc5	67	17	histology	histology	NN
cord-355208-hpldjsc5	67	18	.	.	.
cord-355208-hpldjsc5	68	1	If	if	IN
cord-355208-hpldjsc5	68	2	COVID-19	COVID-19	NNP
cord-355208-hpldjsc5	68	3	is	be	VBZ
cord-355208-hpldjsc5	68	4	indeed	indeed	RB
cord-355208-hpldjsc5	68	5	primarily	primarily	RB
cord-355208-hpldjsc5	68	6	a	a	DT
cord-355208-hpldjsc5	68	7	vascular	vascular	JJ
cord-355208-hpldjsc5	68	8	disorder	disorder	NN
cord-355208-hpldjsc5	68	9	,	,	,
cord-355208-hpldjsc5	68	10	early	early	JJ
cord-355208-hpldjsc5	68	11	invasive	invasive	JJ
cord-355208-hpldjsc5	68	12	mechanical	mechanical	JJ
cord-355208-hpldjsc5	68	13	ventilation	ventilation	NN
cord-355208-hpldjsc5	68	14	should	should	MD
cord-355208-hpldjsc5	68	15	be	be	VB
cord-355208-hpldjsc5	68	16	initiated	initiate	VBN
cord-355208-hpldjsc5	68	17	cautiously	cautiously	RB
cord-355208-hpldjsc5	68	18	.	.	.
cord-355208-hpldjsc5	69	1	Investigations	investigation	NNS
cord-355208-hpldjsc5	69	2	should	should	MD
cord-355208-hpldjsc5	69	3	examine	examine	VB
cord-355208-hpldjsc5	69	4	the	the	DT
cord-355208-hpldjsc5	69	5	impact	impact	NN
cord-355208-hpldjsc5	69	6	of	of	IN
cord-355208-hpldjsc5	69	7	liberal	liberal	JJ
cord-355208-hpldjsc5	69	8	versus	versus	IN
cord-355208-hpldjsc5	69	9	restrictive	restrictive	JJ
cord-355208-hpldjsc5	69	10	invasive	invasive	JJ
cord-355208-hpldjsc5	69	11	mechanical	mechanical	JJ
cord-355208-hpldjsc5	69	12	ventilation	ventilation	NN
cord-355208-hpldjsc5	69	13	strategies	strategy	NNS
cord-355208-hpldjsc5	69	14	.	.	.
cord-355208-hpldjsc5	70	1	We	-PRON-	PRP
cord-355208-hpldjsc5	70	2	reiterate	reiterate	VBP
cord-355208-hpldjsc5	70	3	that	that	IN
cord-355208-hpldjsc5	70	4	there	there	EX
cord-355208-hpldjsc5	70	5	is	be	VBZ
cord-355208-hpldjsc5	70	6	no	no	DT
cord-355208-hpldjsc5	70	7	evidence	evidence	NN
cord-355208-hpldjsc5	70	8	that	that	IN
cord-355208-hpldjsc5	70	9	COVID-19	covid-19	CD
cord-355208-hpldjsc5	70	10	patients	patient	NNS
cord-355208-hpldjsc5	70	11	develop	develop	VBP
cord-355208-hpldjsc5	70	12	"	"	``
cord-355208-hpldjsc5	70	13	cytokine	cytokine	JJ
cord-355208-hpldjsc5	70	14	storm	storm	NN
cord-355208-hpldjsc5	70	15	.	.	.
cord-355208-hpldjsc5	70	16	"	"	''
cord-355208-hpldjsc5	71	1	This	this	DT
cord-355208-hpldjsc5	71	2	finding	finding	NN
cord-355208-hpldjsc5	71	3	suggests	suggest	VBZ
cord-355208-hpldjsc5	71	4	that	that	IN
cord-355208-hpldjsc5	71	5	the	the	DT
cord-355208-hpldjsc5	71	6	use	use	NN
cord-355208-hpldjsc5	71	7	of	of	IN
cord-355208-hpldjsc5	71	8	cytokine	cytokine	NN
cord-355208-hpldjsc5	71	9	-	-	HYPH
cord-355208-hpldjsc5	71	10	blockade	blockade	NN
cord-355208-hpldjsc5	71	11	agents	agent	NNS
cord-355208-hpldjsc5	71	12	should	should	MD
cord-355208-hpldjsc5	71	13	meet	meet	VB
cord-355208-hpldjsc5	71	14	with	with	IN
cord-355208-hpldjsc5	71	15	skepticism	skepticism	NN
cord-355208-hpldjsc5	71	16	in	in	IN
cord-355208-hpldjsc5	71	17	the	the	DT
cord-355208-hpldjsc5	71	18	absence	absence	NN
cord-355208-hpldjsc5	71	19	of	of	IN
cord-355208-hpldjsc5	71	20	randomized	randomized	JJ
cord-355208-hpldjsc5	71	21	evidence	evidence	NN
cord-355208-hpldjsc5	71	22	.	.	.
cord-355208-hpldjsc5	72	1	However	however	RB
cord-355208-hpldjsc5	72	2	,	,	,
cord-355208-hpldjsc5	72	3	anticoagulation	anticoagulation	NN
cord-355208-hpldjsc5	72	4	should	should	MD
cord-355208-hpldjsc5	72	5	be	be	VB
cord-355208-hpldjsc5	72	6	a	a	DT
cord-355208-hpldjsc5	72	7	key	key	JJ
cord-355208-hpldjsc5	72	8	priority	priority	NN
cord-355208-hpldjsc5	72	9	for	for	IN
cord-355208-hpldjsc5	72	10	investigation	investigation	NN
cord-355208-hpldjsc5	72	11	.	.	.
cord-355208-hpldjsc5	73	1	Similarly	similarly	RB
cord-355208-hpldjsc5	73	2	,	,	,
cord-355208-hpldjsc5	73	3	given	give	VBN
cord-355208-hpldjsc5	73	4	the	the	DT
cord-355208-hpldjsc5	73	5	putative	putative	JJ
cord-355208-hpldjsc5	73	6	role	role	NN
cord-355208-hpldjsc5	73	7	of	of	IN
cord-355208-hpldjsc5	73	8	AngII	AngII	NNP
cord-355208-hpldjsc5	73	9	deficiency	deficiency	NN
cord-355208-hpldjsc5	73	10	,	,	,
cord-355208-hpldjsc5	73	11	a	a	DT
cord-355208-hpldjsc5	73	12	randomized	randomized	JJ
cord-355208-hpldjsc5	73	13	trial	trial	NN
cord-355208-hpldjsc5	73	14	of	of	IN
cord-355208-hpldjsc5	73	15	angiotensin	angiotensin	NN
cord-355208-hpldjsc5	73	16	-	-	HYPH
cord-355208-hpldjsc5	73	17	II	II	NNP
cord-355208-hpldjsc5	73	18	treatment	treatment	NN
cord-355208-hpldjsc5	73	19	in	in	IN
cord-355208-hpldjsc5	73	20	COVID-19	covid-19	CD
cord-355208-hpldjsc5	73	21	patients	patient	NNS
cord-355208-hpldjsc5	73	22	who	who	WP
cord-355208-hpldjsc5	73	23	have	have	VBP
cord-355208-hpldjsc5	73	24	progressed	progress	VBN
cord-355208-hpldjsc5	73	25	to	to	TO
cord-355208-hpldjsc5	73	26	shock	shock	VB
cord-355208-hpldjsc5	73	27	is	be	VBZ
cord-355208-hpldjsc5	73	28	warranted	warrant	VBN
cord-355208-hpldjsc5	73	29	.	.	.
cord-355208-hpldjsc5	74	1	Illness	illness	NN
cord-355208-hpldjsc5	74	2	progression	progression	NN
cord-355208-hpldjsc5	74	3	may	may	MD
cord-355208-hpldjsc5	74	4	also	also	RB
cord-355208-hpldjsc5	74	5	be	be	VB
cord-355208-hpldjsc5	74	6	an	an	DT
cord-355208-hpldjsc5	74	7	effect	effect	NN
cord-355208-hpldjsc5	74	8	modifier	modifier	NN
cord-355208-hpldjsc5	74	9	,	,	,
cord-355208-hpldjsc5	74	10	with	with	IN
cord-355208-hpldjsc5	74	11	potential	potential	JJ
cord-355208-hpldjsc5	74	12	benefits	benefit	NNS
cord-355208-hpldjsc5	74	13	of	of	IN
cord-355208-hpldjsc5	74	14	anti	anti	JJ
cord-355208-hpldjsc5	74	15	-	-	JJ
cord-355208-hpldjsc5	74	16	inflammation	inflammation	JJ
cord-355208-hpldjsc5	74	17	and	and	CC
cord-355208-hpldjsc5	74	18	angiotensin	angiotensin	NN
cord-355208-hpldjsc5	74	19	blockade	blockade	NN
cord-355208-hpldjsc5	74	20	earlier	early	RBR
cord-355208-hpldjsc5	74	21	in	in	IN
cord-355208-hpldjsc5	74	22	critical	critical	JJ
cord-355208-hpldjsc5	74	23	disease	disease	NN
cord-355208-hpldjsc5	74	24	and	and	CC
cord-355208-hpldjsc5	74	25	harms	harm	VBZ
cord-355208-hpldjsc5	74	26	at	at	IN
cord-355208-hpldjsc5	74	27	later	later	JJ
cord-355208-hpldjsc5	74	28	time	time	NN
cord-355208-hpldjsc5	74	29	points	point	NNS
cord-355208-hpldjsc5	74	30	.	.	.
cord-355208-hpldjsc5	75	1	COVID	COVID	NNP
cord-355208-hpldjsc5	75	2	-	-	HYPH
cord-355208-hpldjsc5	75	3	induced	induce	VBN
cord-355208-hpldjsc5	75	4	respiratory	respiratory	JJ
cord-355208-hpldjsc5	75	5	failure	failure	NN
cord-355208-hpldjsc5	75	6	involves	involve	VBZ
cord-355208-hpldjsc5	75	7	physiologic	physiologic	JJ
cord-355208-hpldjsc5	75	8	,	,	,
cord-355208-hpldjsc5	75	9	clinical	clinical	JJ
cord-355208-hpldjsc5	75	10	,	,	,
cord-355208-hpldjsc5	75	11	and	and	CC
cord-355208-hpldjsc5	75	12	immunologic	immunologic	JJ
cord-355208-hpldjsc5	75	13	phenotypes	phenotype	NNS
cord-355208-hpldjsc5	75	14	that	that	WDT
cord-355208-hpldjsc5	75	15	are	be	VBP
cord-355208-hpldjsc5	75	16	not	not	RB
cord-355208-hpldjsc5	75	17	consistent	consistent	JJ
cord-355208-hpldjsc5	75	18	with	with	IN
cord-355208-hpldjsc5	75	19	either	either	DT
cord-355208-hpldjsc5	75	20	ARDS	ARDS	NNP
cord-355208-hpldjsc5	75	21	or	or	CC
cord-355208-hpldjsc5	75	22	cytokine	cytokine	NN
cord-355208-hpldjsc5	75	23	-	-	HYPH
cord-355208-hpldjsc5	75	24	release	release	NN
cord-355208-hpldjsc5	75	25	syndromes	syndrome	NNS
cord-355208-hpldjsc5	75	26	.	.	.
cord-355208-hpldjsc5	76	1	COVID-19	COVID-19	NNP
cord-355208-hpldjsc5	76	2	instead	instead	RB
cord-355208-hpldjsc5	76	3	reflects	reflect	VBZ
cord-355208-hpldjsc5	76	4	immunosuppression	immunosuppression	NN
cord-355208-hpldjsc5	76	5	and	and	CC
cord-355208-hpldjsc5	76	6	features	feature	VBZ
cord-355208-hpldjsc5	76	7	compatible	compatible	JJ
cord-355208-hpldjsc5	76	8	with	with	IN
cord-355208-hpldjsc5	76	9	vascular	vascular	JJ
cord-355208-hpldjsc5	76	10	disease	disease	NN
cord-355208-hpldjsc5	76	11	.	.	.
cord-355208-hpldjsc5	77	1	The	the	DT
cord-355208-hpldjsc5	77	2	online	online	JJ
cord-355208-hpldjsc5	77	3	version	version	NN
cord-355208-hpldjsc5	77	4	of	of	IN
cord-355208-hpldjsc5	77	5	this	this	DT
cord-355208-hpldjsc5	77	6	article	article	NN
cord-355208-hpldjsc5	77	7	(	(	-LRB-
cord-355208-hpldjsc5	77	8	https	https	NNP
cord-355208-hpldjsc5	77	9	:	:	:
cord-355208-hpldjsc5	77	10	//doi.org/10.1007	//doi.org/10.1007	.
cord-355208-hpldjsc5	77	11	/	/	SYM
cord-355208-hpldjsc5	77	12	s0013	s0013	NNP
cord-355208-hpldjsc5	77	13	4	4	CD
cord-355208-hpldjsc5	77	14	-	-	HYPH
cord-355208-hpldjsc5	77	15	020	020	CD
cord-355208-hpldjsc5	77	16	-	-	HYPH
cord-355208-hpldjsc5	77	17	06059	06059	CD
cord-355208-hpldjsc5	77	18	-6	-6	CD
cord-355208-hpldjsc5	77	19	)	)	-RRB-
cord-355208-hpldjsc5	77	20	contains	contain	VBZ
cord-355208-hpldjsc5	77	21	supplementary	supplementary	JJ
cord-355208-hpldjsc5	77	22	material	material	NN
cord-355208-hpldjsc5	77	23	,	,	,
cord-355208-hpldjsc5	77	24	which	which	WDT
cord-355208-hpldjsc5	77	25	is	be	VBZ
cord-355208-hpldjsc5	77	26	available	available	JJ
cord-355208-hpldjsc5	77	27	to	to	IN
cord-355208-hpldjsc5	77	28	authorized	authorize	VBN
cord-355208-hpldjsc5	77	29	users	user	NNS
cord-355208-hpldjsc5	77	30	.	.	.
cord-355208-hpldjsc5	78	1	Covid-19	Covid-19	NNP
cord-355208-hpldjsc5	78	2	does	do	VBZ
cord-355208-hpldjsc5	78	3	not	not	RB
cord-355208-hpldjsc5	78	4	lead	lead	VB
cord-355208-hpldjsc5	78	5	to	to	IN
cord-355208-hpldjsc5	78	6	a	a	DT
cord-355208-hpldjsc5	78	7	"	"	``
cord-355208-hpldjsc5	78	8	typical	typical	JJ
cord-355208-hpldjsc5	78	9	"	"	''
cord-355208-hpldjsc5	78	10	acute	acute	JJ
cord-355208-hpldjsc5	78	11	respiratory	respiratory	JJ
cord-355208-hpldjsc5	78	12	distress	distress	NN
cord-355208-hpldjsc5	78	13	syndrome	syndrome	NN
cord-355208-hpldjsc5	79	1	COVID-19	COVID-19	NNP
cord-355208-hpldjsc5	79	2	pneumonia	pneumonia	NN
cord-355208-hpldjsc5	79	3	:	:	:
cord-355208-hpldjsc5	79	4	different	different	JJ
cord-355208-hpldjsc5	79	5	respiratory	respiratory	JJ
cord-355208-hpldjsc5	79	6	treatment	treatment	NN
cord-355208-hpldjsc5	79	7	for	for	IN
cord-355208-hpldjsc5	79	8	different	different	JJ
cord-355208-hpldjsc5	79	9	phenotypes	phenotype	NNS
cord-355208-hpldjsc5	79	10	?	?	.
cord-355208-hpldjsc5	80	1	Dysregulation	dysregulation	NN
cord-355208-hpldjsc5	80	2	of	of	IN
cord-355208-hpldjsc5	80	3	immune	immune	JJ
cord-355208-hpldjsc5	80	4	response	response	NN
cord-355208-hpldjsc5	80	5	in	in	IN
cord-355208-hpldjsc5	80	6	patients	patient	NNS
cord-355208-hpldjsc5	80	7	with	with	IN
cord-355208-hpldjsc5	80	8	COVID-19	COVID-19	NNP
cord-355208-hpldjsc5	80	9	in	in	IN
cord-355208-hpldjsc5	80	10	Wuhan	Wuhan	NNP
cord-355208-hpldjsc5	80	11	,	,	,
cord-355208-hpldjsc5	80	12	China	China	NNP
cord-355208-hpldjsc5	80	13	Development	Development	NNP
cord-355208-hpldjsc5	80	14	and	and	CC
cord-355208-hpldjsc5	80	15	validation	validation	NN
cord-355208-hpldjsc5	80	16	of	of	IN
cord-355208-hpldjsc5	80	17	parsimonious	parsimonious	JJ
cord-355208-hpldjsc5	80	18	algorithms	algorithm	NNS
cord-355208-hpldjsc5	80	19	to	to	TO
cord-355208-hpldjsc5	80	20	classify	classify	VB
cord-355208-hpldjsc5	80	21	acute	acute	JJ
cord-355208-hpldjsc5	80	22	respiratory	respiratory	JJ
cord-355208-hpldjsc5	80	23	distress	distress	NN
cord-355208-hpldjsc5	80	24	syndrome	syndrome	NN
cord-355208-hpldjsc5	80	25	phenotypes	phenotype	NNS
cord-355208-hpldjsc5	80	26	:	:	:
cord-355208-hpldjsc5	80	27	a	a	DT
cord-355208-hpldjsc5	80	28	secondary	secondary	JJ
cord-355208-hpldjsc5	80	29	analysis	analysis	NN
cord-355208-hpldjsc5	80	30	of	of	IN
cord-355208-hpldjsc5	80	31	randomised	randomised	JJ
cord-355208-hpldjsc5	80	32	controlled	control	VBN
cord-355208-hpldjsc5	80	33	trials	trial	NNS
cord-355208-hpldjsc5	80	34	Chimeric	chimeric	JJ
cord-355208-hpldjsc5	80	35	antigen	antigen	NN
cord-355208-hpldjsc5	80	36	receptor	receptor	NN
cord-355208-hpldjsc5	80	37	T	t	NN
cord-355208-hpldjsc5	80	38	cells	cell	NNS
cord-355208-hpldjsc5	80	39	for	for	IN
cord-355208-hpldjsc5	80	40	sustained	sustained	JJ
cord-355208-hpldjsc5	80	41	remissions	remission	NNS
cord-355208-hpldjsc5	80	42	in	in	IN
cord-355208-hpldjsc5	80	43	leukemia	leukemia	NN
cord-355208-hpldjsc5	80	44	Chest	Chest	NNP
cord-355208-hpldjsc5	80	45	CT	CT	NNP
cord-355208-hpldjsc5	80	46	features	feature	NNS
cord-355208-hpldjsc5	80	47	of	of	IN
cord-355208-hpldjsc5	80	48	COVID-19	covid-19	CD
cord-355208-hpldjsc5	80	49	in	in	IN
cord-355208-hpldjsc5	80	50	Findings	finding	NNS
cord-355208-hpldjsc5	80	51	of	of	IN
cord-355208-hpldjsc5	80	52	acute	acute	JJ
cord-355208-hpldjsc5	80	53	pulmonary	pulmonary	JJ
cord-355208-hpldjsc5	80	54	embolism	embolism	NN
cord-355208-hpldjsc5	80	55	in	in	IN
cord-355208-hpldjsc5	80	56	COVID-19	COVID-19	NNP
cord-355208-hpldjsc5	80	57	patients	patient	NNS
cord-355208-hpldjsc5	80	58	(	(	-LRB-
cord-355208-hpldjsc5	80	59	3/1/2020	3/1/2020	CD
cord-355208-hpldjsc5	80	60	)	)	-RRB-
cord-355208-hpldjsc5	80	61	Pulmonary	pulmonary	JJ
cord-355208-hpldjsc5	80	62	pathology	pathology	NN
cord-355208-hpldjsc5	80	63	of	of	IN
cord-355208-hpldjsc5	80	64	early	early	JJ
cord-355208-hpldjsc5	80	65	-	-	HYPH
cord-355208-hpldjsc5	80	66	phase	phase	NN
cord-355208-hpldjsc5	80	67	2019	2019	CD
cord-355208-hpldjsc5	80	68	novel	novel	NN
cord-355208-hpldjsc5	80	69	coronavirus	coronavirus	NN
cord-355208-hpldjsc5	80	70	(	(	-LRB-
cord-355208-hpldjsc5	80	71	COVID-19	COVID-19	NNP
cord-355208-hpldjsc5	80	72	)	)	-RRB-
cord-355208-hpldjsc5	80	73	pneumonia	pneumonia	NN
cord-355208-hpldjsc5	80	74	in	in	IN
cord-355208-hpldjsc5	80	75	two	two	CD
cord-355208-hpldjsc5	80	76	patients	patient	NNS
cord-355208-hpldjsc5	80	77	with	with	IN
cord-355208-hpldjsc5	80	78	lung	lung	NN
cord-355208-hpldjsc5	80	79	cancer	cancer	NN
cord-355208-hpldjsc5	80	80	Coagulopathy	Coagulopathy	NNP
cord-355208-hpldjsc5	80	81	and	and	CC
cord-355208-hpldjsc5	80	82	antiphospholipid	antiphospholipid	NNP
cord-355208-hpldjsc5	80	83	antibodies	antibody	NNS
cord-355208-hpldjsc5	80	84	in	in	IN
cord-355208-hpldjsc5	80	85	patients	patient	NNS
cord-355208-hpldjsc5	80	86	with	with	IN
cord-355208-hpldjsc5	80	87	Covid-19	Covid-19	NNP
cord-355208-hpldjsc5	80	88	Renal	Renal	NNP
cord-355208-hpldjsc5	80	89	histopathological	histopathological	NNP
cord-355208-hpldjsc5	80	90	analysis	analysis	NN
cord-355208-hpldjsc5	80	91	of	of	IN
cord-355208-hpldjsc5	80	92	26	26	CD
cord-355208-hpldjsc5	80	93	postmortem	postmortem	JJ
cord-355208-hpldjsc5	80	94	findings	finding	NNS
cord-355208-hpldjsc5	80	95	of	of	IN
cord-355208-hpldjsc5	80	96	patients	patient	NNS
cord-355208-hpldjsc5	80	97	with	with	IN
cord-355208-hpldjsc5	80	98	COVID-19	COVID-19	NNP
cord-355208-hpldjsc5	80	99	in	in	IN
cord-355208-hpldjsc5	80	100	China	China	NNP
cord-355208-hpldjsc5	80	101	Composition	Composition	NNP
cord-355208-hpldjsc5	80	102	and	and	CC
cord-355208-hpldjsc5	80	103	divergence	divergence	NN
cord-355208-hpldjsc5	80	104	of	of	IN
cord-355208-hpldjsc5	80	105	coronavirus	coronavirus	NN
cord-355208-hpldjsc5	80	106	spike	spike	NN
cord-355208-hpldjsc5	80	107	proteins	protein	NNS
cord-355208-hpldjsc5	80	108	and	and	CC
cord-355208-hpldjsc5	80	109	host	host	NN
cord-355208-hpldjsc5	80	110	ACE2	ACE2	NNP
cord-355208-hpldjsc5	80	111	receptors	receptor	NNS
cord-355208-hpldjsc5	80	112	predict	predict	VBP
cord-355208-hpldjsc5	80	113	potential	potential	JJ
cord-355208-hpldjsc5	80	114	intermediate	intermediate	JJ
cord-355208-hpldjsc5	80	115	hosts	host	NNS
cord-355208-hpldjsc5	80	116	of	of	IN
cord-355208-hpldjsc5	80	117	SARS	SARS	NNP
cord-355208-hpldjsc5	80	118	-	-	HYPH
cord-355208-hpldjsc5	80	119	CoV-2	CoV-2	NNP
cord-355208-hpldjsc5	80	120	Coronaviruses	Coronaviruses	NNPS
cord-355208-hpldjsc5	80	121	:	:	:
cord-355208-hpldjsc5	80	122	an	an	DT
cord-355208-hpldjsc5	80	123	overview	overview	NN
cord-355208-hpldjsc5	80	124	of	of	IN
cord-355208-hpldjsc5	80	125	their	-PRON-	PRP$
cord-355208-hpldjsc5	80	126	replication	replication	NN
cord-355208-hpldjsc5	80	127	and	and	CC
cord-355208-hpldjsc5	80	128	pathogenesis	pathogenesis	NN
cord-355208-hpldjsc5	80	129	Clinical	clinical	JJ
cord-355208-hpldjsc5	80	130	and	and	CC
cord-355208-hpldjsc5	80	131	biochemical	biochemical	JJ
cord-355208-hpldjsc5	80	132	indexes	index	NNS
cord-355208-hpldjsc5	80	133	from	from	IN
cord-355208-hpldjsc5	80	134	2019-nCoV	2019-ncov	CD
cord-355208-hpldjsc5	80	135	infected	infect	VBN
cord-355208-hpldjsc5	80	136	patients	patient	NNS
cord-355208-hpldjsc5	80	137	linked	link	VBN
cord-355208-hpldjsc5	80	138	to	to	IN
cord-355208-hpldjsc5	80	139	viral	viral	JJ
cord-355208-hpldjsc5	80	140	loads	load	NNS
cord-355208-hpldjsc5	80	141	and	and	CC
cord-355208-hpldjsc5	80	142	lung	lung	NN
cord-355208-hpldjsc5	80	143	injury	injury	NN
cord-355208-hpldjsc5	80	144	Responses	response	NNS
cord-355208-hpldjsc5	80	145	of	of	IN
cord-355208-hpldjsc5	80	146	serum	serum	NN
cord-355208-hpldjsc5	80	147	and	and	CC
cord-355208-hpldjsc5	80	148	lung	lung	NN
cord-355208-hpldjsc5	80	149	angiotensin	angiotensin	NN
cord-355208-hpldjsc5	80	150	-	-	HYPH
cord-355208-hpldjsc5	80	151	converting	convert	VBG
cord-355208-hpldjsc5	80	152	enzyme	enzyme	NN
cord-355208-hpldjsc5	80	153	activities	activity	NNS
cord-355208-hpldjsc5	80	154	in	in	IN
cord-355208-hpldjsc5	80	155	the	the	DT
cord-355208-hpldjsc5	80	156	early	early	JJ
cord-355208-hpldjsc5	80	157	phase	phase	NN
cord-355208-hpldjsc5	80	158	of	of	IN
cord-355208-hpldjsc5	80	159	pulmonary	pulmonary	JJ
cord-355208-hpldjsc5	80	160	damage	damage	NN
cord-355208-hpldjsc5	80	161	induced	induce	VBN
cord-355208-hpldjsc5	80	162	by	by	IN
cord-355208-hpldjsc5	80	163	oleic	oleic	JJ
cord-355208-hpldjsc5	80	164	acid	acid	NN
cord-355208-hpldjsc5	80	165	in	in	IN
cord-355208-hpldjsc5	80	166	dogs	dog	NNS
cord-355208-hpldjsc5	80	167	Angiotensin	Angiotensin	NNP
cord-355208-hpldjsc5	80	168	II	II	NNP
cord-355208-hpldjsc5	80	169	type	type	NN
cord-355208-hpldjsc5	80	170	2	2	CD
cord-355208-hpldjsc5	80	171	receptor	receptor	NN
cord-355208-hpldjsc5	80	172	provides	provide	VBZ
cord-355208-hpldjsc5	80	173	an	an	DT
cord-355208-hpldjsc5	80	174	endogenous	endogenous	JJ
cord-355208-hpldjsc5	80	175	brake	brake	NN
cord-355208-hpldjsc5	80	176	during	during	IN
cord-355208-hpldjsc5	80	177	inflammation	inflammation	NN
cord-355208-hpldjsc5	80	178	-	-	HYPH
cord-355208-hpldjsc5	80	179	induced	induce	VBN
cord-355208-hpldjsc5	80	180	microvascular	microvascular	JJ
cord-355208-hpldjsc5	80	181	fluid	fluid	JJ
cord-355208-hpldjsc5	80	182	leak	leak	NN