id author title date pages extension mime words sentences flesch summary cache txt cord-288821-nalulzfo Bastien, Nathalie Human Coronavirus NL63 Infection in Canada 2005-02-15 .txt text/plain 1861 105 60 Although, in a study like this one, the inclusion of a control group of healthy individuals is necessary to clearly demonstrate a causal relationship, the detection of HCoV-NL63 in respiratory-tract specimens from patients suffering from ARI of unknown causes strongly suggests that it is associated with respiratory illness. We detected the presence of HCoV-NL63 in 19 (3.6%) of the 525 analyzed specimens that were negative for (1) influenza viruses A and B; (2) PIV 1, 2, and 3; (3) adenovirus; (4) RSV; and (5) hMPV; and these results provide further evidence of the contribution of HCoV-NL63 to ARI-and of the significant burden that it therefore may present to health-care systems. Thus, the systematic detection of HCoV-NL63 in respiratory specimens may improve the understanding of the etiology of ARI; however, the possibility of dual infection cannot be excluded, because the present study utilized samples from patients with ARI who were tested-and found to be negative-for only (1) influenza viruses A and B; (2) PIV 1, 2, and 3; (3) adenovirus; (4) RSV; and (5) hMPV. ./cache/cord-288821-nalulzfo.txt ./txt/cord-288821-nalulzfo.txt