id author title date pages extension mime words sentences flesch summary cache txt cord-263556-y8vx4ie2 Koistinen, Annamari Prednisolone for the first rhinovirus‐induced wheezing and 4‐year asthma risk: A randomized trial 2017-08-06 .txt text/plain 2996 184 53 Based on our previous findings, 8, 9 we hypothesized that in children with high rhinovirus genome load, the effect of OCS is likely to last beyond 12 months by reducing the need for initiation of long-term asthma control medication. Second, in the placebo group, asthma risk was high: regular asthma control medication was initiated to all children with high rhinovirus genome load during the subsequent 14 months after the first acute rhinovirus-induced wheezing episode. No difference was found in overall analysis F I G U R E 3 The time to initiation of asthma control medication in children randomized to receive prednisolone or placebo for the first rhinovirus-induced wheezing episode. 9 In summary, early systemic short-course prednisolone treatment may be beneficial in reducing the risk for asthma control medication during the first 5 years in first-time wheezing preschool children whose episode was severe and associated with high rhinovirus genome load. ./cache/cord-263556-y8vx4ie2.txt ./txt/cord-263556-y8vx4ie2.txt