id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-289697-g24xib4l	MacDowell, Ana L.	Infectious triggers of asthma	2005-03-01		.txt	text/plain	7774	353	37	In addition to viral infections, RTIs with atypical organisms, such as Mycoplasma pneumoniae and Chlamydia pneumoniae, precipitate a significant proportion of acute episodes of wheezing, contribute to the severity and persistence of asthma, and may serve as the initial insult that leads to development of asthma [17] [18] [19] . The time course of influenza-induced asthma exacerbations was examined retrospectively in 20 asthmatic children 8 to 12 years of age with acute respiratory symptoms [28] . Respiratory syncytial virus (RSV) infects almost 100% of children by 2 years of age and is the most common cause of bronchiolitis and pneumonia in infants [34] . Thus, despite the efficacy of inhaled corticosteroids in the control of asthma and reduction of exacerbations, patients continue to experience exacerbations, particularly in the setting of viral RTIs. Several treatment approaches have been investigated in an attempt to reduce the morbidity associated with wheezing associated with RTIs. Brunette et al [98] examined the effect of a short course of oral corticosteroid administered in an unblinded manner at onset of URI symptoms in a group of children with histories of recurrent wheezing in the setting of viral infections.	./cache/cord-289697-g24xib4l.txt	./txt/cord-289697-g24xib4l.txt