id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-351565-ryjxbqno	Johnston, S. L.	Bronchial hyperresponsiveness and cytokines in virus‐induced asthma exacerbations	2006-04-27		.txt	text/plain	1679	69	43	In recent years studies employing new sensitive molecular methods of identification for the most common upper respiratory tract viruses (coronavirus and rhinovirus) have demonstrated that viral infections are associated with the majority of asthma exacerbations in children and adults in the community [1, 2] . In this issue of the journal a further detailed study employing experimental rhinovirus infection reports on both these aspects, demonstrating that bronchial hyperreactivity is induced and that IL-8 may play a role in the induction of bronchial hyperreactivity and therefore possibly in exacerbations of asthma [9] . In this study atopic asthmatic subjects were challenged with rhinovirus 16 or placebo and the severity of the cold and asthma symptoms monitored along with bronchial hyperreactivity, pulmonary function, nasal lavage IL-8 levels and peripheral blood lymphocyte and neutrophil counts.	./cache/cord-351565-ryjxbqno.txt	./txt/cord-351565-ryjxbqno.txt