id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-007577-f1jzbtjj	Raphael Shulman, N.	Hepatitis-associated antigen	2006-09-18		.txt	text/plain	13821	577	39	Frequency of HAA in acute hepatitis: After the initial suggestion in 1967 by Blumberg and co-workers [4] that Australia antigen might be related to the infectious agent of viral hepatitis, and the demonstration in 1968 by Okochi and Murakami [5] and Prince [6] that the antigen appeared in blood of patients during the incubation period of serum hepatitis, a number of investigators reported further evidence for existence of a hepatitis-associated antigen (Table II) . The antibodies used diagnostically to measure HAA by precipitin and complement fixation technics all come from patients who have received multiple transfusions and in whom high titer "hyperimmune" anti-HAA developed apparently as a result of repeated exposure to antigen in transfused blood. [29] tested serum obtained at weekly intervals from twenty-two patients with HAA-positive hepatitis during a one to two month period after onset of disease and found only one antibody detectable by agar gel precipitin technics and two antibodies of low titer detectable only by complement fixation.	./cache/cord-007577-f1jzbtjj.txt	./txt/cord-007577-f1jzbtjj.txt