id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-005748-2rpiv4d9	Giantsou, Elpis	De-escalation therapy rates are significantly higher by bronchoalveolar lavage than by tracheal aspirate	2007-06-05		.txt	text/plain	3804	166	38	Therefore, the objective of this study was to assess outcomes in association with the implementation of de-escalation therapy in a well-defined group of patients [11] who had developed VAP as confirmed by two separate cultures, one quantitative tracheal aspirate and one bronchoalveolar lavage (BAL) sample, that both had to be positive. The microbiological information that the attending physicians used to de-escalate antibiotic therapy, to establish the appropriateness of the initial antibiotic regimen and to confirm the diagnosis of VAP, in patients with clinical suspicion for infection, was derived from quantitative tracheal aspirate or BAL. Percentages may not add up to 100 because of combination multi-drug regimens and isolates with more than one pathogen grown at significant concentration Table 3 Antibiotics initially prescribed and pathogens identified in the respiratory sample that guided de-escalation therapy decisions in 143 patients with ventilator-associated pneumonia in 18.9% and elective surgery in 23.1%.	./cache/cord-005748-2rpiv4d9.txt	./txt/cord-005748-2rpiv4d9.txt