id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-006676-a21tdgns	Abul, H.	Levels of IL-8 and myeloperoxidase in the lungs of pneumonia patients	2001		.txt	text/plain	3622	209	50	Interleukin-8 (IL-8) is considered as the major polymorphonuclear neutrophils (PMNs) chemoattractant cytokine in lung diseases such as asthma and adult respiratory distress syndrome (ARDS). The level of IL-8 mRNA, protein and myeloperoxidase present in the cells of the bronchioalveolar lavages (BALs) taken from the areas of known pneumonic consolidations on chest X-ray (infected lung) are compared with the BALs obtained from areas of no obvious infiltrate (non-infected lung). Therefore this study is designed to measure the site-specific increase in the level of IL-8 in the lung of patients with bacterial pneumonia as compared to that of the non-smoking control group. The level of IL-8 mRNA and protein present in the BAL obtained from subsegmental bronchi of experimental and control group of patients were determined by RT-PCR assay and enzyme immunoassay respectively. In this study we also determined the level of myeloperoxidase activity in the cells collected from 1 ml of BAL each from the infected and non-infected lung.	./cache/cord-006676-a21tdgns.txt	./txt/cord-006676-a21tdgns.txt