id author title date pages extension mime words sentences flesch summary cache txt cord-271734-1cfhjuxi Vergkizi, Souzan Bacillus Calmette–Guérin (BCG) vaccine generates immunoregulatory cells in the cervical lymph nodes in guinea pigs injected intra dermally 2020-10-16 .txt text/plain 5707 272 48 This work demonstrates the presence of immune regulatory cells in the cervical lymph nodes draining Bacillus Calmette-Guérin (BCG) vaccinated site on the dorsum of the ear in guinea pigs. The objective of this work was to investigate the immune regulatory mechanism responsible for the induction of an 'immunological' type granuloma in the draining lymph node after BCG vaccination in guinea pigs and their early resolution in contrast to that observed with another mycobacterium, M. The effects of injected BCG and M leprae on the stimulation index (T/C) measured in the post auricular and cervical lymph node cell preparations cultured with PPD, leprosin, concavalin A, or BCG: live, heat killed or co-irr were compared using student's t-test for means comparison. leprae injected guinea pigs, cells from the cervical lymph nodes draining BCG induced granuloma did not respond in vitro to soluble mycobacterial antigens, PPD and leprosin, though they responded to whole BCG organisms. ./cache/cord-271734-1cfhjuxi.txt ./txt/cord-271734-1cfhjuxi.txt