id author title date pages extension mime words sentences flesch summary cache txt cord-294302-hboc3xcz Roncati, Luca COVID-19 vaccine and boosted immunity: nothing ad interim to do? 2020-10-09 .txt text/plain 2275 127 37 Here, we illustrate the immunological mechanism to train the immune system towards a more effective and less symptomatic T-helper 1 (Th1) immune response, thanks to a subcutaneous vaccine containing lysates of Corynebacterium parvum (synonym for Propionibacterium acnes), a Gram-positive bacterium able to evoke a strong Th1 response. parvum vaccine protection against a coronavirus (mouse hepatitis virus type 3), dating back to 1981 murine model by Schindler and colleagues, is also reported [31] . parvum vaccine (point 3), it is theoretically possible to train and calibrate the immune system towards a T h 1 response (point 4), able to prevent COVID-19 or to keep the disease under control in a paucisymptomatic or asymptomatic way thanks to activated reticuloendothelial system, NK, T c and dendritic cells. Efficacy of BCG vaccination in the prevention of COVID19 via the strengthening of innate immunity in health care workers ./cache/cord-294302-hboc3xcz.txt ./txt/cord-294302-hboc3xcz.txt