id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-309888-93rdcwrh	Tamás, Fazekas	COVID-19 research: promising tracks leading to uro-oncology	2020-05-11		.txt	text/plain	1786	101	48	First of all, we would like to underline the potential protective effect of Bacillus Calmette Guerin (BCG) vaccination against Covid-19 [4] . Based on these findings, the Murdoch Children's Research Institute in Australia and the Radboud University in the Netherland have launched prospective clinical trials enrolling health care workers, to assess whether BCG vaccination protects against Sars-CoV-2 infection or reduces its severity [11, 12] . All these considerations raise some interesting questions: (1) is androgen deprivation therapy able to downregulate TMPRSS2 in lung epithelial cells, and if so is it able to affect the susceptibility and/or severity of Covid-19 infection? (2) Is the known male predominance of Sars-CoV-2 infection/Covid-19 severity related to the androgen-dependent regulation of TMPRSS2 gene? (3) Does individual variability of TMPRSS2 expression (e.g. caused by polymorphism) have any impact on Sars-CoV-2 infection/ Covid-19 severity?	./cache/cord-309888-93rdcwrh.txt	./txt/cord-309888-93rdcwrh.txt