id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-302690-0v7ne7vi	Chow, Clara K.	Ultra-low-dose quadruple combination blood pressure lowering therapy in patients with hypertension: The QUARTET randomized controlled trial protocol()	2020-10-02		.txt	text/plain	5606	309	56	title: Ultra-low-dose quadruple combination blood pressure lowering therapy in patients with hypertension: The QUARTET randomized controlled trial protocol() The QUARTET (Quadruple UltrA-low-dose tReaTment for hypErTension) double-blind, active controlled, randomized clinical trial will examine whether ultra-low-dose quadruple combination therapy is more effective than guideline recommended standard care, in lowering blood pressure. The primary objective of the Quadruple UltrA-low-dose tReatment for hypErTension (QUARTET) trial is to examine 153 whether ultra-low-dose quadruple combination therapy (quadpill) is more effective than guideline recommended 154 therapy with an ARB plus a CCB if required in lowering blood pressure. Participants are 159 randomized in a 1:1 allocation ratio using a central computer-based service, to initial therapy with quadpill or to a 160 standard dose of an ARB, with a CCB added as required, as per current guideline recommendations ( Figure 1 ). Fixed low-dose triple combination antihypertensive medication vs usual 683 care for blood pressure control in patients with mild to moderate hypertension in sri lanka: A randomized 684 clinical trial	./cache/cord-302690-0v7ne7vi.txt	./txt/cord-302690-0v7ne7vi.txt