id	sid	tid	token	lemma	pos
cord-022561-rv5j1201	1	1	key	key	NNP
cord-022561-rv5j1201	1	2	:	:	:
cord-022561-rv5j1201	1	3	cord-022561-rv5j1201	cord-022561-rv5j1201	NNS
cord-022561-rv5j1201	1	4	authors	author	NNS
cord-022561-rv5j1201	1	5	:	:	:
cord-022561-rv5j1201	1	6	Boes	Boes	NNP
cord-022561-rv5j1201	1	7	,	,	,
cord-022561-rv5j1201	1	8	Katie	Katie	NNP
cord-022561-rv5j1201	1	9	M.	M.	NNP
cord-022561-rv5j1201	1	10	;	;	:
cord-022561-rv5j1201	1	11	Durham	Durham	NNP
cord-022561-rv5j1201	1	12	,	,	,
cord-022561-rv5j1201	1	13	Amy	Amy	NNP
cord-022561-rv5j1201	1	14	C.	C.	NNP
cord-022561-rv5j1201	1	15	title	title	NN
cord-022561-rv5j1201	1	16	:	:	:
cord-022561-rv5j1201	1	17	Bone	Bone	NNP
cord-022561-rv5j1201	1	18	Marrow	Marrow	NNP
cord-022561-rv5j1201	1	19	,	,	,
cord-022561-rv5j1201	1	20	Blood	blood	NN
cord-022561-rv5j1201	1	21	Cells	cell	NNS
cord-022561-rv5j1201	1	22	,	,	,
cord-022561-rv5j1201	1	23	and	and	CC
cord-022561-rv5j1201	1	24	the	the	DT
cord-022561-rv5j1201	1	25	Lymphoid	Lymphoid	NNP
cord-022561-rv5j1201	1	26	/	/	SYM
cord-022561-rv5j1201	1	27	Lymphatic	Lymphatic	NNP
cord-022561-rv5j1201	1	28	System	System	NNP
cord-022561-rv5j1201	1	29	date	date	NN
cord-022561-rv5j1201	1	30	:	:	:
cord-022561-rv5j1201	1	31	2017	2017	CD
cord-022561-rv5j1201	1	32	-	-	HYPH
cord-022561-rv5j1201	1	33	02	02	CD
cord-022561-rv5j1201	1	34	-	-	SYM
cord-022561-rv5j1201	1	35	17	17	CD
cord-022561-rv5j1201	1	36	journal	journal	NN
cord-022561-rv5j1201	1	37	:	:	:
cord-022561-rv5j1201	1	38	Pathologic	Pathologic	NNP
cord-022561-rv5j1201	1	39	Basis	Basis	NNP
cord-022561-rv5j1201	1	40	of	of	IN
cord-022561-rv5j1201	1	41	Veterinary	Veterinary	NNP
cord-022561-rv5j1201	1	42	Disease	Disease	NNP
cord-022561-rv5j1201	1	43	DOI	DOI	NNP
cord-022561-rv5j1201	1	44	:	:	:
cord-022561-rv5j1201	2	1	10.1016	10.1016	CD
cord-022561-rv5j1201	2	2	/	/	SYM
cord-022561-rv5j1201	2	3	b978	b978	NNP
cord-022561-rv5j1201	2	4	-	-	HYPH
cord-022561-rv5j1201	2	5	0	0	CD
cord-022561-rv5j1201	2	6	-	-	HYPH
cord-022561-rv5j1201	2	7	323	323	CD
cord-022561-rv5j1201	2	8	-	-	HYPH
cord-022561-rv5j1201	2	9	35775	35775	CD
cord-022561-rv5j1201	2	10	-	-	HYPH
cord-022561-rv5j1201	2	11	3.00013	3.00013	CD
cord-022561-rv5j1201	2	12	-	-	SYM
cord-022561-rv5j1201	2	13	8	8	CD
cord-022561-rv5j1201	2	14	sha	sha	NN
cord-022561-rv5j1201	2	15	:	:	:
cord-022561-rv5j1201	3	1	ac35d77f6055a6a310af0c67ac4fba2f3950bab9	ac35d77f6055a6a310af0c67ac4fba2f3950bab9	NNP
cord-022561-rv5j1201	3	2	doc_id	doc_id	CD
cord-022561-rv5j1201	3	3	:	:	:
cord-022561-rv5j1201	4	1	22561	22561	CD
cord-022561-rv5j1201	5	1	cord_uid	cord_uid	NN
cord-022561-rv5j1201	5	2	:	:	:
cord-022561-rv5j1201	6	1	rv5j1201	rv5j1201	NFP
cord-022561-rv5j1201	6	2	nan	nan	NNP
cord-022561-rv5j1201	7	1	Within	within	IN
cord-022561-rv5j1201	7	2	the	the	DT
cord-022561-rv5j1201	7	3	marrow	marrow	NN
cord-022561-rv5j1201	7	4	spaces	space	NNS
cord-022561-rv5j1201	7	5	,	,	,
cord-022561-rv5j1201	7	6	a	a	DT
cord-022561-rv5j1201	7	7	network	network	NN
cord-022561-rv5j1201	7	8	of	of	IN
cord-022561-rv5j1201	7	9	stromal	stromal	JJ
cord-022561-rv5j1201	7	10	cells	cell	NNS
cord-022561-rv5j1201	7	11	and	and	CC
cord-022561-rv5j1201	7	12	extracellular	extracellular	JJ
cord-022561-rv5j1201	7	13	matrix	matrix	NN
cord-022561-rv5j1201	7	14	provides	provide	VBZ
cord-022561-rv5j1201	7	15	metabolic	metabolic	JJ
cord-022561-rv5j1201	7	16	and	and	CC
cord-022561-rv5j1201	7	17	structural	structural	JJ
cord-022561-rv5j1201	7	18	support	support	NN
cord-022561-rv5j1201	7	19	to	to	IN
cord-022561-rv5j1201	7	20	hematopoietic	hematopoietic	JJ
cord-022561-rv5j1201	7	21	cells	cell	NNS
cord-022561-rv5j1201	7	22	.	.	.
cord-022561-rv5j1201	8	1	These	these	DT
cord-022561-rv5j1201	8	2	stromal	stromal	JJ
cord-022561-rv5j1201	8	3	cells	cell	NNS
cord-022561-rv5j1201	8	4	consist	consist	VBP
cord-022561-rv5j1201	8	5	of	of	IN
cord-022561-rv5j1201	8	6	adipocytes	adipocyte	NNS
cord-022561-rv5j1201	8	7	and	and	CC
cord-022561-rv5j1201	8	8	specialized	specialized	JJ
cord-022561-rv5j1201	8	9	fibroblasts	fibroblast	NNS
cord-022561-rv5j1201	8	10	,	,	,
cord-022561-rv5j1201	8	11	called	call	VBN
cord-022561-rv5j1201	8	12	reticular	reticular	JJ
cord-022561-rv5j1201	8	13	cells	cell	NNS
cord-022561-rv5j1201	8	14	.	.	.
cord-022561-rv5j1201	9	1	The	the	DT
cord-022561-rv5j1201	9	2	latter	latter	JJ
cord-022561-rv5j1201	9	3	provides	provide	VBZ
cord-022561-rv5j1201	9	4	structural	structural	JJ
cord-022561-rv5j1201	9	5	support	support	NN
cord-022561-rv5j1201	9	6	by	by	IN
cord-022561-rv5j1201	9	7	producing	produce	VBG
cord-022561-rv5j1201	9	8	a	a	DT
cord-022561-rv5j1201	9	9	fine	fine	JJ
cord-022561-rv5j1201	9	10	network	network	NN
cord-022561-rv5j1201	9	11	of	of	IN
cord-022561-rv5j1201	9	12	a	a	DT
cord-022561-rv5j1201	9	13	type	type	NN
cord-022561-rv5j1201	9	14	of	of	IN
cord-022561-rv5j1201	9	15	collagen	collagen	NN
cord-022561-rv5j1201	9	16	,	,	,
cord-022561-rv5j1201	9	17	called	call	VBN
cord-022561-rv5j1201	9	18	reticulin	reticulin	NNP
cord-022561-rv5j1201	9	19	,	,	,
cord-022561-rv5j1201	9	20	and	and	CC
cord-022561-rv5j1201	9	21	by	by	IN
cord-022561-rv5j1201	9	22	extending	extend	VBG
cord-022561-rv5j1201	9	23	long	long	JJ
cord-022561-rv5j1201	9	24	cytoplasmic	cytoplasmic	JJ
cord-022561-rv5j1201	9	25	processes	process	NNS
cord-022561-rv5j1201	9	26	around	around	IN
cord-022561-rv5j1201	9	27	other	other	JJ
cord-022561-rv5j1201	9	28	cells	cell	NNS
cord-022561-rv5j1201	9	29	and	and	CC
cord-022561-rv5j1201	9	30	structures	structure	NNS
cord-022561-rv5j1201	9	31	.	.	.
cord-022561-rv5j1201	10	1	Both	both	CC
cord-022561-rv5j1201	10	2	reticulin	reticulin	NN
cord-022561-rv5j1201	10	3	and	and	CC
cord-022561-rv5j1201	10	4	cytoplasmic	cytoplasmic	JJ
cord-022561-rv5j1201	10	5	processes	process	NNS
cord-022561-rv5j1201	10	6	are	be	VBP
cord-022561-rv5j1201	10	7	not	not	RB
cord-022561-rv5j1201	10	8	normally	normally	RB
cord-022561-rv5j1201	10	9	visible	visible	JJ
cord-022561-rv5j1201	10	10	with	with	IN
cord-022561-rv5j1201	10	11	light	light	JJ
cord-022561-rv5j1201	10	12	microscopy	microscopy	NNS
cord-022561-rv5j1201	10	13	but	but	CC
cord-022561-rv5j1201	10	14	are	be	VBP
cord-022561-rv5j1201	10	15	visible	visible	JJ
cord-022561-rv5j1201	10	16	with	with	IN
cord-022561-rv5j1201	10	17	silver	silver	JJ
cord-022561-rv5j1201	10	18	reticulin	reticulin	NN
cord-022561-rv5j1201	10	19	stains	stain	NNS
cord-022561-rv5j1201	10	20	(	(	-LRB-
cord-022561-rv5j1201	10	21	e.g.	e.g.	RB
cord-022561-rv5j1201	10	22	,	,	,
cord-022561-rv5j1201	10	23	Gordon	Gordon	NNP
cord-022561-rv5j1201	10	24	and	and	CC
cord-022561-rv5j1201	10	25	Sweet	Sweet	NNP
cord-022561-rv5j1201	10	26	's	's	POS
cord-022561-rv5j1201	10	27	and	and	CC
cord-022561-rv5j1201	10	28	sometimes	sometimes	RB
cord-022561-rv5j1201	10	29	with	with	IN
cord-022561-rv5j1201	10	30	periodic	periodic	JJ
cord-022561-rv5j1201	10	31	acid	acid	NN
cord-022561-rv5j1201	10	32	-	-	HYPH
cord-022561-rv5j1201	10	33	Schiff	Schiff	NNP
cord-022561-rv5j1201	10	34	)	)	-RRB-
cord-022561-rv5j1201	10	35	.	.	.
cord-022561-rv5j1201	11	1	Bone	bone	NN
cord-022561-rv5j1201	11	2	marrow	marrow	NN
cord-022561-rv5j1201	11	3	is	be	VBZ
cord-022561-rv5j1201	11	4	highly	highly	RB
cord-022561-rv5j1201	11	5	vascularized	vascularized	JJ
cord-022561-rv5j1201	11	6	but	but	CC
cord-022561-rv5j1201	11	7	does	do	VBZ
cord-022561-rv5j1201	11	8	not	not	RB
cord-022561-rv5j1201	11	9	have	have	VB
cord-022561-rv5j1201	11	10	lymphatic	lymphatic	JJ
cord-022561-rv5j1201	11	11	drainage	drainage	NN
cord-022561-rv5j1201	11	12	.	.	.
cord-022561-rv5j1201	12	1	Marrow	marrow	NN
cord-022561-rv5j1201	12	2	of	of	IN
cord-022561-rv5j1201	12	3	long	long	JJ
cord-022561-rv5j1201	12	4	bones	bone	NNS
cord-022561-rv5j1201	12	5	receives	receive	VBZ
cord-022561-rv5j1201	12	6	part	part	NN
cord-022561-rv5j1201	12	7	of	of	IN
cord-022561-rv5j1201	12	8	its	-PRON-	PRP$
cord-022561-rv5j1201	12	9	blood	blood	NN
cord-022561-rv5j1201	12	10	supply	supply	NN
cord-022561-rv5j1201	12	11	from	from	IN
cord-022561-rv5j1201	12	12	the	the	DT
cord-022561-rv5j1201	12	13	nutrient	nutrient	NN
cord-022561-rv5j1201	12	14	artery	artery	NN
cord-022561-rv5j1201	12	15	,	,	,
cord-022561-rv5j1201	12	16	which	which	WDT
cord-022561-rv5j1201	12	17	enters	enter	VBZ
cord-022561-rv5j1201	12	18	the	the	DT
cord-022561-rv5j1201	12	19	bone	bone	NN
cord-022561-rv5j1201	12	20	via	via	IN
cord-022561-rv5j1201	12	21	the	the	DT
cord-022561-rv5j1201	12	22	nutrient	nutrient	NN
cord-022561-rv5j1201	12	23	canal	canal	NN
cord-022561-rv5j1201	12	24	at	at	IN
cord-022561-rv5j1201	12	25	midshaft	midshaft	NN
cord-022561-rv5j1201	12	26	.	.	.
cord-022561-rv5j1201	13	1	The	the	DT
cord-022561-rv5j1201	13	2	remaining	remain	VBG
cord-022561-rv5j1201	13	3	arterial	arterial	JJ
cord-022561-rv5j1201	13	4	supply	supply	NN
cord-022561-rv5j1201	13	5	enters	enter	VBZ
cord-022561-rv5j1201	13	6	the	the	DT
cord-022561-rv5j1201	13	7	marrow	marrow	NN
cord-022561-rv5j1201	13	8	through	through	IN
cord-022561-rv5j1201	13	9	an	an	DT
cord-022561-rv5j1201	13	10	anastomosing	anastomosing	JJ
cord-022561-rv5j1201	13	11	array	array	NN
cord-022561-rv5j1201	13	12	of	of	IN
cord-022561-rv5j1201	13	13	vessels	vessel	NNS
cord-022561-rv5j1201	13	14	that	that	WDT
cord-022561-rv5j1201	13	15	arise	arise	VBP
cord-022561-rv5j1201	13	16	from	from	IN
cord-022561-rv5j1201	13	17	the	the	DT
cord-022561-rv5j1201	13	18	periosteal	periosteal	NN
cord-022561-rv5j1201	13	19	arteries	artery	NNS
cord-022561-rv5j1201	13	20	and	and	CC
cord-022561-rv5j1201	13	21	penetrate	penetrate	VB
cord-022561-rv5j1201	13	22	the	the	DT
cord-022561-rv5j1201	13	23	cortical	cortical	JJ
cord-022561-rv5j1201	13	24	bone	bone	NN
cord-022561-rv5j1201	13	25	.	.	.
cord-022561-rv5j1201	14	1	Vessels	vessel	NNS
cord-022561-rv5j1201	14	2	from	from	IN
cord-022561-rv5j1201	14	3	the	the	DT
cord-022561-rv5j1201	14	4	nutrient	nutrient	NN
cord-022561-rv5j1201	14	5	and	and	CC
cord-022561-rv5j1201	14	6	periosteal	periosteal	NN
cord-022561-rv5j1201	14	7	arteries	artery	NNS
cord-022561-rv5j1201	14	8	converge	converge	VBP
cord-022561-rv5j1201	14	9	and	and	CC
cord-022561-rv5j1201	14	10	form	form	VBP
cord-022561-rv5j1201	14	11	an	an	DT
cord-022561-rv5j1201	14	12	interweaving	interweave	VBG
cord-022561-rv5j1201	14	13	network	network	NN
cord-022561-rv5j1201	14	14	of	of	IN
cord-022561-rv5j1201	14	15	venous	venous	JJ
cord-022561-rv5j1201	14	16	sinusoids	sinusoid	NNS
cord-022561-rv5j1201	14	17	that	that	WDT
cord-022561-rv5j1201	14	18	permeates	permeate	VBZ
cord-022561-rv5j1201	14	19	the	the	DT
cord-022561-rv5j1201	14	20	marrow	marrow	NN
cord-022561-rv5j1201	14	21	.	.	.
cord-022561-rv5j1201	15	1	These	these	DT
cord-022561-rv5j1201	15	2	sinusoids	sinusoid	NNS
cord-022561-rv5j1201	15	3	not	not	RB
cord-022561-rv5j1201	15	4	only	only	RB
cord-022561-rv5j1201	15	5	deliver	deliver	VBP
cord-022561-rv5j1201	15	6	nutrients	nutrient	NNS
cord-022561-rv5j1201	15	7	and	and	CC
cord-022561-rv5j1201	15	8	remove	remove	VB
cord-022561-rv5j1201	15	9	cellular	cellular	JJ
cord-022561-rv5j1201	15	10	waste	waste	NN
cord-022561-rv5j1201	15	11	but	but	CC
cord-022561-rv5j1201	15	12	also	also	RB
cord-022561-rv5j1201	15	13	act	act	VB
cord-022561-rv5j1201	15	14	as	as	IN
cord-022561-rv5j1201	15	15	the	the	DT
cord-022561-rv5j1201	15	16	entry	entry	NN
cord-022561-rv5j1201	15	17	point	point	NN
cord-022561-rv5j1201	15	18	for	for	IN
cord-022561-rv5j1201	15	19	hematopoietic	hematopoietic	JJ
cord-022561-rv5j1201	15	20	cells	cell	NNS
cord-022561-rv5j1201	15	21	into	into	IN
cord-022561-rv5j1201	15	22	blood	blood	NN
cord-022561-rv5j1201	15	23	circulation	circulation	NN
cord-022561-rv5j1201	15	24	.	.	.
cord-022561-rv5j1201	16	1	Sinusoidal	sinusoidal	JJ
cord-022561-rv5j1201	16	2	endothelial	endothelial	JJ
cord-022561-rv5j1201	16	3	cells	cell	NNS
cord-022561-rv5j1201	16	4	function	function	VBP
cord-022561-rv5j1201	16	5	as	as	IN
cord-022561-rv5j1201	16	6	a	a	DT
cord-022561-rv5j1201	16	7	barrier	barrier	NN
cord-022561-rv5j1201	16	8	and	and	CC
cord-022561-rv5j1201	16	9	regulate	regulate	VB
cord-022561-rv5j1201	16	10	traffic	traffic	NN
cord-022561-rv5j1201	16	11	of	of	IN
cord-022561-rv5j1201	16	12	chemicals	chemical	NNS
cord-022561-rv5j1201	16	13	and	and	CC
cord-022561-rv5j1201	16	14	particles	particle	NNS
cord-022561-rv5j1201	16	15	between	between	IN
cord-022561-rv5j1201	16	16	the	the	DT
cord-022561-rv5j1201	16	17	intravascular	intravascular	JJ
cord-022561-rv5j1201	16	18	and	and	CC
cord-022561-rv5j1201	16	19	extravascular	extravascular	JJ
cord-022561-rv5j1201	16	20	spaces	space	NNS
cord-022561-rv5j1201	16	21	.	.	.
cord-022561-rv5j1201	17	1	Venous	venous	JJ
cord-022561-rv5j1201	17	2	drainage	drainage	NN
cord-022561-rv5j1201	17	3	parallels	parallel	NNS
cord-022561-rv5j1201	18	1	that	that	DT
cord-022561-rv5j1201	18	2	of	of	IN
cord-022561-rv5j1201	18	3	the	the	DT
cord-022561-rv5j1201	18	4	nutrient	nutrient	NN
cord-022561-rv5j1201	18	5	artery	artery	NN
cord-022561-rv5j1201	18	6	and	and	CC
cord-022561-rv5j1201	18	7	its	-PRON-	PRP$
cord-022561-rv5j1201	18	8	extensions	extension	NNS
cord-022561-rv5j1201	18	9	.	.	.
cord-022561-rv5j1201	19	1	•	•	NNP
cord-022561-rv5j1201	20	1	Bleeding	bleed	VBG
cord-022561-rv5j1201	20	2	time	time	NN
cord-022561-rv5j1201	20	3	(	(	-LRB-
cord-022561-rv5j1201	20	4	template	template	NN
cord-022561-rv5j1201	20	5	bleeding	bleed	VBG
cord-022561-rv5j1201	20	6	time	time	NN
cord-022561-rv5j1201	20	7	,	,	,
cord-022561-rv5j1201	20	8	buccal	buccal	JJ
cord-022561-rv5j1201	20	9	mucosal	mucosal	JJ
cord-022561-rv5j1201	20	10	bleeding	bleed	VBG
cord-022561-rv5j1201	20	11	time	time	NN
cord-022561-rv5j1201	20	12	)	)	-RRB-
cord-022561-rv5j1201	20	13	.	.	.
cord-022561-rv5j1201	21	1	This	this	DT
cord-022561-rv5j1201	21	2	assay	assay	NN
cord-022561-rv5j1201	21	3	assesses	assess	VBZ
cord-022561-rv5j1201	21	4	primary	primary	JJ
cord-022561-rv5j1201	21	5	hemostasis	hemostasis	NN
cord-022561-rv5j1201	21	6	(	(	-LRB-
cord-022561-rv5j1201	21	7	platelet	platelet	NN
cord-022561-rv5j1201	21	8	plug	plug	NN
cord-022561-rv5j1201	21	9	formation	formation	NN
cord-022561-rv5j1201	21	10	)	)	-RRB-
cord-022561-rv5j1201	21	11	by	by	IN
cord-022561-rv5j1201	21	12	measuring	measure	VBG
cord-022561-rv5j1201	21	13	the	the	DT
cord-022561-rv5j1201	21	14	time	time	NN
cord-022561-rv5j1201	21	15	interval	interval	NN
cord-022561-rv5j1201	21	16	between	between	IN
cord-022561-rv5j1201	21	17	inflicting	inflicting	NN
cord-022561-rv5j1201	21	18	of	of	IN
cord-022561-rv5j1201	21	19	standardized	standardized	JJ
cord-022561-rv5j1201	21	20	wound	wound	NN
cord-022561-rv5j1201	21	21	and	and	CC
cord-022561-rv5j1201	21	22	cessation	cessation	NN
cord-022561-rv5j1201	21	23	of	of	IN
cord-022561-rv5j1201	21	24	bleeding	bleed	VBG
cord-022561-rv5j1201	21	25	.	.	.
cord-022561-rv5j1201	22	1	Sedation	sedation	NN
cord-022561-rv5j1201	22	2	may	may	MD
cord-022561-rv5j1201	22	3	be	be	VB
cord-022561-rv5j1201	22	4	required	require	VBN
cord-022561-rv5j1201	22	5	.	.	.
cord-022561-rv5j1201	23	1	In	in	IN
cord-022561-rv5j1201	23	2	small	small	JJ
cord-022561-rv5j1201	23	3	animals	animal	NNS
cord-022561-rv5j1201	23	4	the	the	DT
cord-022561-rv5j1201	23	5	test	test	NN
cord-022561-rv5j1201	23	6	is	be	VBZ
cord-022561-rv5j1201	23	7	usually	usually	RB
cord-022561-rv5j1201	23	8	performed	perform	VBN
cord-022561-rv5j1201	23	9	on	on	IN
cord-022561-rv5j1201	23	10	the	the	DT
cord-022561-rv5j1201	23	11	buccal	buccal	JJ
cord-022561-rv5j1201	23	12	mucosa	mucosa	NN
cord-022561-rv5j1201	23	13	;	;	:
cord-022561-rv5j1201	23	14	in	in	IN
cord-022561-rv5j1201	23	15	large	large	JJ
cord-022561-rv5j1201	23	16	animals	animal	NNS
cord-022561-rv5j1201	23	17	it	-PRON-	PRP
cord-022561-rv5j1201	23	18	may	may	MD
cord-022561-rv5j1201	23	19	be	be	VB
cord-022561-rv5j1201	23	20	performed	perform	VBN
cord-022561-rv5j1201	23	21	on	on	IN
cord-022561-rv5j1201	23	22	the	the	DT
cord-022561-rv5j1201	23	23	distal	distal	JJ
cord-022561-rv5j1201	23	24	limb	limb	NN
cord-022561-rv5j1201	23	25	.	.	.
cord-022561-rv5j1201	24	1	Prolonged	prolonged	JJ
cord-022561-rv5j1201	24	2	bleeding	bleed	VBG
cord-022561-rv5j1201	24	3	time	time	NN
cord-022561-rv5j1201	24	4	may	may	MD
cord-022561-rv5j1201	24	5	be	be	VB
cord-022561-rv5j1201	24	6	because	because	IN
cord-022561-rv5j1201	24	7	of	of	IN
cord-022561-rv5j1201	24	8	a	a	DT
cord-022561-rv5j1201	24	9	platelet	platelet	NN
cord-022561-rv5j1201	24	10	function	function	NN
cord-022561-rv5j1201	24	11	defect	defect	NN
cord-022561-rv5j1201	24	12	,	,	,
cord-022561-rv5j1201	24	13	von	von	NNP
cord-022561-rv5j1201	24	14	Willebrand	Willebrand	NNP
cord-022561-rv5j1201	24	15	disease	disease	NN
cord-022561-rv5j1201	24	16	,	,	,
cord-022561-rv5j1201	24	17	or	or	CC
cord-022561-rv5j1201	24	18	a	a	DT
cord-022561-rv5j1201	24	19	vascular	vascular	JJ
cord-022561-rv5j1201	24	20	defect	defect	NN
cord-022561-rv5j1201	24	21	.	.	.
cord-022561-rv5j1201	25	1	The	the	DT
cord-022561-rv5j1201	25	2	sensitivity	sensitivity	NN
cord-022561-rv5j1201	25	3	of	of	IN
cord-022561-rv5j1201	25	4	this	this	DT
cord-022561-rv5j1201	25	5	test	test	NN
cord-022561-rv5j1201	25	6	is	be	VBZ
cord-022561-rv5j1201	25	7	low	low	JJ
cord-022561-rv5j1201	25	8	;	;	:
cord-022561-rv5j1201	25	9	reference	reference	NN
cord-022561-rv5j1201	25	10	intervals	interval	NNS
cord-022561-rv5j1201	25	11	are	be	VBP
cord-022561-rv5j1201	25	12	species	specie	NNS
cord-022561-rv5j1201	25	13	and	and	CC
cord-022561-rv5j1201	25	14	site	site	NN
cord-022561-rv5j1201	25	15	dependent	dependent	JJ
cord-022561-rv5j1201	25	16	(	(	-LRB-
cord-022561-rv5j1201	25	17	can	can	MD
cord-022561-rv5j1201	25	18	perform	perform	VB
cord-022561-rv5j1201	25	19	test	test	NN
cord-022561-rv5j1201	25	20	on	on	IN
cord-022561-rv5j1201	25	21	a	a	DT
cord-022561-rv5j1201	25	22	normal	normal	JJ
cord-022561-rv5j1201	25	23	animal	animal	NN
cord-022561-rv5j1201	25	24	as	as	IN
cord-022561-rv5j1201	25	25	a	a	DT
cord-022561-rv5j1201	25	26	control	control	NN
cord-022561-rv5j1201	25	27	)	)	-RRB-
cord-022561-rv5j1201	25	28	.	.	.
cord-022561-rv5j1201	26	1	This	this	DT
cord-022561-rv5j1201	26	2	test	test	NN
cord-022561-rv5j1201	26	3	is	be	VBZ
cord-022561-rv5j1201	26	4	contraindicated	contraindicate	VBN
cord-022561-rv5j1201	26	5	in	in	IN
cord-022561-rv5j1201	26	6	cases	case	NNS
cord-022561-rv5j1201	26	7	of	of	IN
cord-022561-rv5j1201	26	8	thrombocytopenia	thrombocytopenia	NN
cord-022561-rv5j1201	26	9	because	because	IN
cord-022561-rv5j1201	26	10	significant	significant	JJ
cord-022561-rv5j1201	26	11	thrombocytopenia	thrombocytopenia	NN
cord-022561-rv5j1201	26	12	can	can	MD
cord-022561-rv5j1201	26	13	cause	cause	VB
cord-022561-rv5j1201	26	14	a	a	DT
cord-022561-rv5j1201	26	15	prolonged	prolonged	JJ
cord-022561-rv5j1201	26	16	bleeding	bleeding	NN
cord-022561-rv5j1201	26	17	time	time	NN
cord-022561-rv5j1201	26	18	(	(	-LRB-
cord-022561-rv5j1201	26	19	invalidates	invalidate	VBZ
cord-022561-rv5j1201	26	20	interpretation	interpretation	NN
cord-022561-rv5j1201	26	21	of	of	IN
cord-022561-rv5j1201	26	22	test	test	NN
cord-022561-rv5j1201	26	23	results	result	NNS
cord-022561-rv5j1201	26	24	)	)	-RRB-
cord-022561-rv5j1201	26	25	.	.	.
cord-022561-rv5j1201	27	1	•	•	NNP
cord-022561-rv5j1201	28	1	Clot	clot	NN
cord-022561-rv5j1201	28	2	retraction	retraction	NN
cord-022561-rv5j1201	28	3	test	test	NN
cord-022561-rv5j1201	28	4	.	.	.
cord-022561-rv5j1201	29	1	This	this	DT
cord-022561-rv5j1201	29	2	assay	assay	NN
cord-022561-rv5j1201	29	3	assesses	assess	VBZ
cord-022561-rv5j1201	29	4	retraction	retraction	NN
cord-022561-rv5j1201	29	5	of	of	IN
cord-022561-rv5j1201	29	6	a	a	DT
cord-022561-rv5j1201	29	7	clot	clot	NN
cord-022561-rv5j1201	29	8	,	,	,
cord-022561-rv5j1201	29	9	in	in	IN
cord-022561-rv5j1201	29	10	which	which	WDT
cord-022561-rv5j1201	29	11	platelets	platelet	NNS
cord-022561-rv5j1201	29	12	play	play	VBP
cord-022561-rv5j1201	29	13	an	an	DT
cord-022561-rv5j1201	29	14	essential	essential	JJ
cord-022561-rv5j1201	29	15	role	role	NN
cord-022561-rv5j1201	29	16	.	.	.
cord-022561-rv5j1201	30	1	This	this	DT
cord-022561-rv5j1201	30	2	is	be	VBZ
cord-022561-rv5j1201	30	3	a	a	DT
cord-022561-rv5j1201	30	4	crude	crude	JJ
cord-022561-rv5j1201	30	5	test	test	NN
cord-022561-rv5j1201	30	6	that	that	WDT
cord-022561-rv5j1201	30	7	is	be	VBZ
cord-022561-rv5j1201	30	8	rarely	rarely	RB
cord-022561-rv5j1201	30	9	performed	perform	VBN
cord-022561-rv5j1201	30	10	.	.	.
cord-022561-rv5j1201	31	1	Different	different	JJ
cord-022561-rv5j1201	31	2	protocols	protocol	NNS
cord-022561-rv5j1201	31	3	are	be	VBP
cord-022561-rv5j1201	31	4	described	describe	VBN
cord-022561-rv5j1201	31	5	.	.	.
cord-022561-rv5j1201	32	1	Significant	significant	JJ
cord-022561-rv5j1201	32	2	thrombocytopenia	thrombocytopenia	NN
cord-022561-rv5j1201	32	3	invalidates	invalidate	VBZ
cord-022561-rv5j1201	32	4	interpretation	interpretation	NN
cord-022561-rv5j1201	32	5	of	of	IN
cord-022561-rv5j1201	32	6	test	test	NN
cord-022561-rv5j1201	32	7	results	result	NNS
cord-022561-rv5j1201	32	8	.	.	.
cord-022561-rv5j1201	33	1	•	•	NNP
cord-022561-rv5j1201	34	1	Tests	test	NNS
cord-022561-rv5j1201	34	2	to	to	TO
cord-022561-rv5j1201	34	3	characterize	characterize	VB
cord-022561-rv5j1201	34	4	platelet	platelet	NN
cord-022561-rv5j1201	34	5	function	function	NN
cord-022561-rv5j1201	34	6	abnormalities	abnormality	NNS
cord-022561-rv5j1201	34	7	more	more	RBR
cord-022561-rv5j1201	34	8	specifically	specifically	RB
cord-022561-rv5j1201	34	9	are	be	VBP
cord-022561-rv5j1201	34	10	available	available	JJ
cord-022561-rv5j1201	34	11	through	through	IN
cord-022561-rv5j1201	34	12	specialized	specialize	VBN
cord-022561-rv5j1201	34	13	laboratories	laboratory	NNS
cord-022561-rv5j1201	34	14	.	.	.
cord-022561-rv5j1201	35	1	•	•	NNP
cord-022561-rv5j1201	36	1	Aggregometry	Aggregometry	NNP
cord-022561-rv5j1201	36	2	-	-	:
cord-022561-rv5j1201	36	3	to	to	TO
cord-022561-rv5j1201	36	4	assess	assess	VB
cord-022561-rv5j1201	36	5	platelet	platelet	NN
cord-022561-rv5j1201	36	6	aggregation	aggregation	NN
cord-022561-rv5j1201	36	7	in	in	IN
cord-022561-rv5j1201	36	8	response	response	NN
cord-022561-rv5j1201	36	9	to	to	IN
cord-022561-rv5j1201	36	10	different	different	JJ
cord-022561-rv5j1201	36	11	physiologic	physiologic	JJ
cord-022561-rv5j1201	36	12	agonists	agonist	NNS
cord-022561-rv5j1201	36	13	.	.	.
cord-022561-rv5j1201	37	1	•	•	NNP
cord-022561-rv5j1201	38	1	Adhesion	adhesion	NN
cord-022561-rv5j1201	38	2	assays-	assays-	NN
cord-022561-rv5j1201	39	1	to	to	TO
cord-022561-rv5j1201	39	2	assess	assess	VB
cord-022561-rv5j1201	39	3	the	the	DT
cord-022561-rv5j1201	39	4	ability	ability	NN
cord-022561-rv5j1201	39	5	of	of	IN
cord-022561-rv5j1201	39	6	platelets	platelet	NNS
cord-022561-rv5j1201	39	7	to	to	TO
cord-022561-rv5j1201	39	8	adhere	adhere	VB
cord-022561-rv5j1201	39	9	to	to	IN
cord-022561-rv5j1201	39	10	a	a	DT
cord-022561-rv5j1201	39	11	substrate	substrate	NN
cord-022561-rv5j1201	39	12	(	(	-LRB-
cord-022561-rv5j1201	39	13	e.g.	e.g.	RB
cord-022561-rv5j1201	39	14	,	,	,
cord-022561-rv5j1201	39	15	collagen	collagen	NN
cord-022561-rv5j1201	39	16	)	)	-RRB-
cord-022561-rv5j1201	39	17	.	.	.
cord-022561-rv5j1201	40	1	•	•	NNP
cord-022561-rv5j1201	41	1	Flow	flow	NN
cord-022561-rv5j1201	41	2	cytometry	cytometry	NN
cord-022561-rv5j1201	41	3	-	-	HYPH
cord-022561-rv5j1201	41	4	to	to	TO
cord-022561-rv5j1201	41	5	assay	assay	NN
cord-022561-rv5j1201	41	6	for	for	IN
cord-022561-rv5j1201	41	7	expression	expression	NN
cord-022561-rv5j1201	41	8	of	of	IN
cord-022561-rv5j1201	41	9	surface	surface	NN
cord-022561-rv5j1201	41	10	molecules	molecule	NNS
cord-022561-rv5j1201	41	11	.	.	.
cord-022561-rv5j1201	42	1	•	•	NNP
cord-022561-rv5j1201	43	1	PFA-100-an	pfa-100-an	JJ
cord-022561-rv5j1201	43	2	instrument	instrument	NN
cord-022561-rv5j1201	43	3	that	that	WDT
cord-022561-rv5j1201	43	4	simulates	simulate	VBZ
cord-022561-rv5j1201	43	5	a	a	DT
cord-022561-rv5j1201	43	6	damaged	damage	VBN
cord-022561-rv5j1201	43	7	blood	blood	NN
cord-022561-rv5j1201	43	8	vessel	vessel	NN
cord-022561-rv5j1201	43	9	,	,	,
cord-022561-rv5j1201	43	10	by	by	IN
cord-022561-rv5j1201	43	11	measuring	measure	VBG
cord-022561-rv5j1201	43	12	time	time	NN
cord-022561-rv5j1201	43	13	for	for	IN
cord-022561-rv5j1201	43	14	a	a	DT
cord-022561-rv5j1201	43	15	platelet	platelet	NN
cord-022561-rv5j1201	43	16	plug	plug	NN
cord-022561-rv5j1201	43	17	to	to	TO
cord-022561-rv5j1201	43	18	occlude	occlude	VB
cord-022561-rv5j1201	43	19	an	an	DT
cord-022561-rv5j1201	43	20	aperture	aperture	NN
cord-022561-rv5j1201	43	21	;	;	:
cord-022561-rv5j1201	43	22	to	to	IN
cord-022561-rv5j1201	43	23	date	date	NN
cord-022561-rv5j1201	43	24	,	,	,
cord-022561-rv5j1201	43	25	this	this	DT
cord-022561-rv5j1201	43	26	instrument	instrument	NN
cord-022561-rv5j1201	43	27	has	have	VBZ
cord-022561-rv5j1201	43	28	mainly	mainly	RB
cord-022561-rv5j1201	43	29	been	be	VBN
cord-022561-rv5j1201	43	30	used	use	VBN
cord-022561-rv5j1201	43	31	in	in	IN
cord-022561-rv5j1201	43	32	research	research	NN
cord-022561-rv5j1201	43	33	applications	application	NNS
cord-022561-rv5j1201	43	34	.	.	.
cord-022561-rv5j1201	44	1	•	•	NNP
cord-022561-rv5j1201	45	1	Thromboelastography	Thromboelastography	NNP
cord-022561-rv5j1201	45	2	(	(	-LRB-
cord-022561-rv5j1201	45	3	TEG)-global	teg)-global	NN
cord-022561-rv5j1201	45	4	assessment	assessment	NN
cord-022561-rv5j1201	45	5	of	of	IN
cord-022561-rv5j1201	45	6	hemostasis	hemostasis	NN
cord-022561-rv5j1201	45	7	(	(	-LRB-
cord-022561-rv5j1201	45	8	platelets	platelet	NNS
cord-022561-rv5j1201	45	9	,	,	,
cord-022561-rv5j1201	45	10	coagulation	coagulation	NN
cord-022561-rv5j1201	45	11	,	,	,
cord-022561-rv5j1201	45	12	and	and	CC
cord-022561-rv5j1201	45	13	fibrinolysis	fibrinolysis	NN
cord-022561-rv5j1201	45	14	)	)	-RRB-
cord-022561-rv5j1201	45	15	based	base	VBN
cord-022561-rv5j1201	45	16	on	on	IN
cord-022561-rv5j1201	45	17	viscoelastic	viscoelastic	JJ
cord-022561-rv5j1201	45	18	analysis	analysis	NN
cord-022561-rv5j1201	45	19	of	of	IN
cord-022561-rv5j1201	45	20	whole	whole	JJ
cord-022561-rv5j1201	45	21	blood	blood	NN
cord-022561-rv5j1201	45	22	.	.	.
cord-022561-rv5j1201	46	1	•	•	NNP
cord-022561-rv5j1201	47	1	Tests	test	NNS
cord-022561-rv5j1201	47	2	for	for	IN
cord-022561-rv5j1201	47	3	immune	immune	NN
cord-022561-rv5j1201	47	4	-	-	HYPH
cord-022561-rv5j1201	47	5	mediated	mediate	VBN
cord-022561-rv5j1201	47	6	thrombocytopenia	thrombocytopenia	NN
cord-022561-rv5j1201	47	7	(	(	-LRB-
cord-022561-rv5j1201	47	8	IMT	IMT	NNP
cord-022561-rv5j1201	47	9	)	)	-RRB-
cord-022561-rv5j1201	47	10	.	.	.
cord-022561-rv5j1201	48	1	•	•	NNP
cord-022561-rv5j1201	49	1	Flow	flow	NN
cord-022561-rv5j1201	49	2	cytometry-	cytometry-	NN
cord-022561-rv5j1201	50	1	to	to	TO
cord-022561-rv5j1201	50	2	detect	detect	VB
cord-022561-rv5j1201	50	3	immunoglobulin	immunoglobulin	NN
cord-022561-rv5j1201	50	4	bound	bind	VBN
cord-022561-rv5j1201	50	5	to	to	IN
cord-022561-rv5j1201	50	6	the	the	DT
cord-022561-rv5j1201	50	7	platelet	platelet	NN
cord-022561-rv5j1201	50	8	surface	surface	NN
cord-022561-rv5j1201	50	9	,	,	,
cord-022561-rv5j1201	50	10	using	use	VBG
cord-022561-rv5j1201	50	11	a	a	DT
cord-022561-rv5j1201	50	12	fluorescent	fluorescent	NN
cord-022561-rv5j1201	50	13	-	-	HYPH
cord-022561-rv5j1201	50	14	labeled	label	VBN
cord-022561-rv5j1201	50	15	antibody	antibody	NN
cord-022561-rv5j1201	50	16	.	.	.
cord-022561-rv5j1201	51	1	•	•	NNP
cord-022561-rv5j1201	51	2	Bone	Bone	NNP
cord-022561-rv5j1201	51	3	marrow	marrow	NN
cord-022561-rv5j1201	51	4	immunofluorescent	immunofluorescent	NN
cord-022561-rv5j1201	51	5	antibody	antibody	NN
cord-022561-rv5j1201	51	6	(	(	-LRB-
cord-022561-rv5j1201	51	7	IFA	IFA	NNP
cord-022561-rv5j1201	51	8	)	)	-RRB-
cord-022561-rv5j1201	51	9	test	test	NN
cord-022561-rv5j1201	51	10	-	-	:
cord-022561-rv5j1201	51	11	to	to	TO
cord-022561-rv5j1201	51	12	detect	detect	VB
cord-022561-rv5j1201	51	13	bound	bind	VBN
cord-022561-rv5j1201	51	14	immunoglobulin	immunoglobulin	NN
cord-022561-rv5j1201	51	15	.	.	.
cord-022561-rv5j1201	52	1	Sometimes	sometimes	RB
cord-022561-rv5j1201	52	2	referred	refer	VBD
cord-022561-rv5j1201	52	3	to	to	IN
cord-022561-rv5j1201	52	4	as	as	IN
cord-022561-rv5j1201	52	5	the	the	DT
cord-022561-rv5j1201	52	6	"	"	``
cord-022561-rv5j1201	52	7	antimegakaryocyte	antimegakaryocyte	NNP
cord-022561-rv5j1201	52	8	antibody	antibody	NNP
cord-022561-rv5j1201	52	9	test	test	NN
cord-022561-rv5j1201	52	10	,	,	,
cord-022561-rv5j1201	52	11	"	"	''
cord-022561-rv5j1201	52	12	this	this	DT
cord-022561-rv5j1201	52	13	assay	assay	NN
cord-022561-rv5j1201	52	14	actually	actually	RB
cord-022561-rv5j1201	52	15	detects	detect	VBZ
cord-022561-rv5j1201	52	16	the	the	DT
cord-022561-rv5j1201	52	17	presence	presence	NN
cord-022561-rv5j1201	52	18	of	of	IN
cord-022561-rv5j1201	52	19	immunoglobulin	immunoglobulin	NN
cord-022561-rv5j1201	52	20	nonspecifically	nonspecifically	RB
cord-022561-rv5j1201	52	21	:	:	:
cord-022561-rv5j1201	52	22	a	a	DT
cord-022561-rv5j1201	52	23	smear	smear	NN
cord-022561-rv5j1201	52	24	of	of	IN
cord-022561-rv5j1201	52	25	a	a	DT
cord-022561-rv5j1201	52	26	bone	bone	NN
cord-022561-rv5j1201	52	27	marrow	marrow	NN
cord-022561-rv5j1201	52	28	aspirate	aspirate	NN
cord-022561-rv5j1201	52	29	is	be	VBZ
cord-022561-rv5j1201	52	30	incubated	incubate	VBN
cord-022561-rv5j1201	52	31	with	with	IN
cord-022561-rv5j1201	52	32	a	a	DT
cord-022561-rv5j1201	52	33	fluorescent	fluorescent	NN
cord-022561-rv5j1201	52	34	-	-	HYPH
cord-022561-rv5j1201	52	35	labeled	label	VBN
cord-022561-rv5j1201	52	36	antibody	antibody	NN
cord-022561-rv5j1201	52	37	to	to	IN
cord-022561-rv5j1201	52	38	species	species	NN
cord-022561-rv5j1201	52	39	-	-	HYPH
cord-022561-rv5j1201	52	40	specific	specific	JJ
cord-022561-rv5j1201	52	41	immunoglobulin	immunoglobulin	NN
cord-022561-rv5j1201	52	42	.	.	.
cord-022561-rv5j1201	53	1	Other	other	JJ
cord-022561-rv5j1201	53	2	components	component	NNS
cord-022561-rv5j1201	53	3	of	of	IN
cord-022561-rv5j1201	53	4	the	the	DT
cord-022561-rv5j1201	53	5	marrow	marrow	NN
cord-022561-rv5j1201	53	6	include	include	VBP
cord-022561-rv5j1201	53	7	myelinated	myelinated	JJ
cord-022561-rv5j1201	53	8	and	and	CC
cord-022561-rv5j1201	53	9	nonmyelinated	nonmyelinated	JJ
cord-022561-rv5j1201	53	10	nerves	nerve	NNS
cord-022561-rv5j1201	53	11	,	,	,
cord-022561-rv5j1201	53	12	as	as	RB
cord-022561-rv5j1201	53	13	well	well	RB
cord-022561-rv5j1201	53	14	as	as	IN
cord-022561-rv5j1201	53	15	low	low	JJ
cord-022561-rv5j1201	53	16	numbers	number	NNS
cord-022561-rv5j1201	53	17	of	of	IN
cord-022561-rv5j1201	53	18	resident	resident	JJ
cord-022561-rv5j1201	53	19	macrophages	macrophage	NNS
cord-022561-rv5j1201	53	20	,	,	,
cord-022561-rv5j1201	53	21	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	53	22	,	,	,
cord-022561-rv5j1201	53	23	and	and	CC
cord-022561-rv5j1201	53	24	plasma	plasma	NN
cord-022561-rv5j1201	53	25	cells	cell	NNS
cord-022561-rv5j1201	53	26	.	.	.
cord-022561-rv5j1201	54	1	Of	of	IN
cord-022561-rv5j1201	54	2	note	note	NN
cord-022561-rv5j1201	54	3	,	,	,
cord-022561-rv5j1201	54	4	the	the	DT
cord-022561-rv5j1201	54	5	macrophages	macrophage	NNS
cord-022561-rv5j1201	54	6	play	play	VBP
cord-022561-rv5j1201	54	7	an	an	DT
cord-022561-rv5j1201	54	8	important	important	JJ
cord-022561-rv5j1201	54	9	role	role	NN
cord-022561-rv5j1201	54	10	in	in	IN
cord-022561-rv5j1201	54	11	iron	iron	NN
cord-022561-rv5j1201	54	12	storage	storage	NN
cord-022561-rv5j1201	54	13	and	and	CC
cord-022561-rv5j1201	54	14	erythrocyte	erythrocyte	NN
cord-022561-rv5j1201	54	15	maturation	maturation	NN
cord-022561-rv5j1201	54	16	.	.	.
cord-022561-rv5j1201	55	1	The	the	DT
cord-022561-rv5j1201	55	2	following	follow	VBG
cord-022561-rv5j1201	55	3	basic	basic	JJ
cord-022561-rv5j1201	55	4	concepts	concept	NNS
cord-022561-rv5j1201	55	5	provide	provide	VBP
cord-022561-rv5j1201	55	6	a	a	DT
cord-022561-rv5j1201	55	7	framework	framework	NN
cord-022561-rv5j1201	55	8	for	for	IN
cord-022561-rv5j1201	55	9	understanding	understand	VBG
cord-022561-rv5j1201	55	10	the	the	DT
cord-022561-rv5j1201	55	11	mechanisms	mechanism	NNS
cord-022561-rv5j1201	55	12	of	of	IN
cord-022561-rv5j1201	55	13	injury	injury	NN
cord-022561-rv5j1201	55	14	and	and	CC
cord-022561-rv5j1201	55	15	diseases	disease	NNS
cord-022561-rv5j1201	55	16	presented	present	VBN
cord-022561-rv5j1201	55	17	later	later	RB
cord-022561-rv5j1201	55	18	in	in	IN
cord-022561-rv5j1201	55	19	the	the	DT
cord-022561-rv5j1201	55	20	chapter	chapter	NN
cord-022561-rv5j1201	55	21	.	.	.
cord-022561-rv5j1201	56	1	•	•	NNP
cord-022561-rv5j1201	57	1	Hematopoietic	hematopoietic	JJ
cord-022561-rv5j1201	57	2	tissue	tissue	NN
cord-022561-rv5j1201	57	3	is	be	VBZ
cord-022561-rv5j1201	57	4	highly	highly	RB
cord-022561-rv5j1201	57	5	proliferative	proliferative	JJ
cord-022561-rv5j1201	57	6	.	.	.
cord-022561-rv5j1201	58	1	Billions	billion	NNS
cord-022561-rv5j1201	58	2	of	of	IN
cord-022561-rv5j1201	58	3	cells	cell	NNS
cord-022561-rv5j1201	58	4	per	per	IN
cord-022561-rv5j1201	58	5	kilogram	kilogram	NN
cord-022561-rv5j1201	58	6	of	of	IN
cord-022561-rv5j1201	58	7	body	body	NN
cord-022561-rv5j1201	58	8	weight	weight	NN
cord-022561-rv5j1201	58	9	are	be	VBP
cord-022561-rv5j1201	58	10	produced	produce	VBN
cord-022561-rv5j1201	58	11	each	each	DT
cord-022561-rv5j1201	58	12	day	day	NN
cord-022561-rv5j1201	58	13	.	.	.
cord-022561-rv5j1201	59	1	•	•	NNP
cord-022561-rv5j1201	60	1	Pluripotent	pluripotent	JJ
cord-022561-rv5j1201	60	2	hematopoietic	hematopoietic	JJ
cord-022561-rv5j1201	60	3	stem	stem	NN
cord-022561-rv5j1201	60	4	cells	cell	NNS
cord-022561-rv5j1201	60	5	are	be	VBP
cord-022561-rv5j1201	60	6	a	a	DT
cord-022561-rv5j1201	60	7	self	self	NN
cord-022561-rv5j1201	60	8	-	-	HYPH
cord-022561-rv5j1201	60	9	renewing	renew	VBG
cord-022561-rv5j1201	60	10	population	population	NN
cord-022561-rv5j1201	60	11	,	,	,
cord-022561-rv5j1201	60	12	giving	give	VBG
cord-022561-rv5j1201	60	13	rise	rise	NN
cord-022561-rv5j1201	60	14	to	to	IN
cord-022561-rv5j1201	60	15	cells	cell	NNS
cord-022561-rv5j1201	60	16	with	with	IN
cord-022561-rv5j1201	60	17	committed	committed	JJ
cord-022561-rv5j1201	60	18	differentiation	differentiation	NN
cord-022561-rv5j1201	60	19	programs	program	NNS
cord-022561-rv5j1201	60	20	,	,	,
cord-022561-rv5j1201	60	21	and	and	CC
cord-022561-rv5j1201	60	22	are	be	VBP
cord-022561-rv5j1201	60	23	common	common	JJ
cord-022561-rv5j1201	60	24	ancestors	ancestor	NNS
cord-022561-rv5j1201	60	25	of	of	IN
cord-022561-rv5j1201	60	26	all	all	DT
cord-022561-rv5j1201	60	27	blood	blood	NN
cord-022561-rv5j1201	60	28	cells	cell	NNS
cord-022561-rv5j1201	60	29	.	.	.
cord-022561-rv5j1201	61	1	The	the	DT
cord-022561-rv5j1201	61	2	process	process	NN
cord-022561-rv5j1201	61	3	of	of	IN
cord-022561-rv5j1201	61	4	hematopoietic	hematopoietic	JJ
cord-022561-rv5j1201	61	5	differentiation	differentiation	NN
cord-022561-rv5j1201	61	6	is	be	VBZ
cord-022561-rv5j1201	61	7	shown	show	VBN
cord-022561-rv5j1201	61	8	in	in	IN
cord-022561-rv5j1201	61	9	Fig	Fig	NNP
cord-022561-rv5j1201	61	10	.	.	.
cord-022561-rv5j1201	62	1	13	13	CD
cord-022561-rv5j1201	62	2	-2	-2	CD
cord-022561-rv5j1201	62	3	.	.	.
cord-022561-rv5j1201	63	1	•	•	NNP
cord-022561-rv5j1201	64	1	Hematopoietic	hematopoietic	JJ
cord-022561-rv5j1201	64	2	cells	cell	NNS
cord-022561-rv5j1201	64	3	undergo	undergo	VBP
cord-022561-rv5j1201	64	4	sequential	sequential	JJ
cord-022561-rv5j1201	64	5	divisions	division	NNS
cord-022561-rv5j1201	64	6	as	as	IN
cord-022561-rv5j1201	64	7	they	-PRON-	PRP
cord-022561-rv5j1201	64	8	develop	develop	VBP
cord-022561-rv5j1201	64	9	,	,	,
cord-022561-rv5j1201	64	10	so	so	CC
cord-022561-rv5j1201	64	11	there	there	EX
cord-022561-rv5j1201	64	12	are	be	VBP
cord-022561-rv5j1201	64	13	progressively	progressively	RB
cord-022561-rv5j1201	64	14	higher	high	JJR
cord-022561-rv5j1201	64	15	numbers	number	NNS
cord-022561-rv5j1201	64	16	of	of	IN
cord-022561-rv5j1201	64	17	cells	cell	NNS
cord-022561-rv5j1201	64	18	as	as	IN
cord-022561-rv5j1201	64	19	they	-PRON-	PRP
cord-022561-rv5j1201	64	20	mature	mature	VBP
cord-022561-rv5j1201	64	21	.	.	.
cord-022561-rv5j1201	65	1	Cells	cell	NNS
cord-022561-rv5j1201	65	2	also	also	RB
cord-022561-rv5j1201	65	3	continue	continue	VBP
cord-022561-rv5j1201	65	4	to	to	TO
cord-022561-rv5j1201	65	5	mature	mature	VB
cord-022561-rv5j1201	65	6	after	after	IN
cord-022561-rv5j1201	65	7	they	-PRON-	PRP
cord-022561-rv5j1201	65	8	have	have	VBP
cord-022561-rv5j1201	65	9	stopped	stop	VBN
cord-022561-rv5j1201	65	10	dividing	divide	VBG
cord-022561-rv5j1201	65	11	.	.	.
cord-022561-rv5j1201	66	1	Conceptually	conceptually	RB
cord-022561-rv5j1201	66	2	,	,	,
cord-022561-rv5j1201	66	3	it	-PRON-	PRP
cord-022561-rv5j1201	66	4	is	be	VBZ
cord-022561-rv5j1201	66	5	helpful	helpful	JJ
cord-022561-rv5j1201	66	6	to	to	TO
cord-022561-rv5j1201	66	7	consider	consider	VB
cord-022561-rv5j1201	66	8	cells	cell	NNS
cord-022561-rv5j1201	66	9	in	in	IN
cord-022561-rv5j1201	66	10	the	the	DT
cord-022561-rv5j1201	66	11	bone	bone	NN
cord-022561-rv5j1201	66	12	marrow	marrow	NN
cord-022561-rv5j1201	66	13	as	as	IN
cord-022561-rv5j1201	66	14	belonging	belong	VBG
cord-022561-rv5j1201	66	15	to	to	IN
cord-022561-rv5j1201	66	16	mitotic	mitotic	JJ
cord-022561-rv5j1201	66	17	and	and	CC
cord-022561-rv5j1201	66	18	postmitotic	postmitotic	JJ
cord-022561-rv5j1201	66	19	compartments	compartment	NNS
cord-022561-rv5j1201	66	20	.	.	.
cord-022561-rv5j1201	67	1	Examples	example	NNS
cord-022561-rv5j1201	67	2	of	of	IN
cord-022561-rv5j1201	67	3	developing	develop	VBG
cord-022561-rv5j1201	67	4	hematopoietic	hematopoietic	JJ
cord-022561-rv5j1201	67	5	cells	cell	NNS
cord-022561-rv5j1201	67	6	are	be	VBP
cord-022561-rv5j1201	67	7	shown	show	VBN
cord-022561-rv5j1201	67	8	in	in	IN
cord-022561-rv5j1201	67	9	Fig	Fig	NNP
cord-022561-rv5j1201	67	10	.	.	.
cord-022561-rv5j1201	68	1	13	13	CD
cord-022561-rv5j1201	69	1	-3	-3	NNP
cord-022561-rv5j1201	69	2	.	.	.
cord-022561-rv5j1201	70	1	•	•	NNP
cord-022561-rv5j1201	71	1	Mature	mature	JJ
cord-022561-rv5j1201	71	2	cells	cell	NNS
cord-022561-rv5j1201	71	3	released	release	VBN
cord-022561-rv5j1201	71	4	into	into	IN
cord-022561-rv5j1201	71	5	the	the	DT
cord-022561-rv5j1201	71	6	blood	blood	NN
cord-022561-rv5j1201	71	7	circulation	circulation	NN
cord-022561-rv5j1201	71	8	have	have	VBP
cord-022561-rv5j1201	71	9	different	different	JJ
cord-022561-rv5j1201	71	10	normal	normal	JJ
cord-022561-rv5j1201	71	11	life	life	NN
cord-022561-rv5j1201	71	12	spans	span	NNS
cord-022561-rv5j1201	71	13	,	,	,
cord-022561-rv5j1201	71	14	varying	vary	VBG
cord-022561-rv5j1201	71	15	from	from	IN
cord-022561-rv5j1201	71	16	hours	hour	NNS
cord-022561-rv5j1201	71	17	(	(	-LRB-
cord-022561-rv5j1201	71	18	neutrophils	neutrophil	NNS
cord-022561-rv5j1201	71	19	)	)	-RRB-
cord-022561-rv5j1201	71	20	,	,	,
cord-022561-rv5j1201	71	21	to	to	IN
cord-022561-rv5j1201	71	22	days	day	NNS
cord-022561-rv5j1201	71	23	(	(	-LRB-
cord-022561-rv5j1201	71	24	platelets	platelet	NNS
cord-022561-rv5j1201	71	25	)	)	-RRB-
cord-022561-rv5j1201	71	26	,	,	,
cord-022561-rv5j1201	71	27	to	to	IN
cord-022561-rv5j1201	71	28	months	month	NNS
cord-022561-rv5j1201	71	29	(	(	-LRB-
cord-022561-rv5j1201	71	30	erythrocytes	erythrocyte	NNS
cord-022561-rv5j1201	71	31	)	)	-RRB-
cord-022561-rv5j1201	71	32	,	,	,
cord-022561-rv5j1201	71	33	and	and	CC
cord-022561-rv5j1201	71	34	to	to	IN
cord-022561-rv5j1201	71	35	years	year	NNS
cord-022561-rv5j1201	71	36	(	(	-LRB-
cord-022561-rv5j1201	71	37	some	some	DT
cord-022561-rv5j1201	71	38	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	71	39	)	)	-RRB-
cord-022561-rv5j1201	71	40	.	.	.
cord-022561-rv5j1201	72	1	•	•	NNP
cord-022561-rv5j1201	73	1	The	the	DT
cord-022561-rv5j1201	73	2	hematopoietic	hematopoietic	JJ
cord-022561-rv5j1201	73	3	system	system	NN
cord-022561-rv5j1201	73	4	is	be	VBZ
cord-022561-rv5j1201	73	5	under	under	IN
cord-022561-rv5j1201	73	6	exquisite	exquisite	JJ
cord-022561-rv5j1201	73	7	local	local	JJ
cord-022561-rv5j1201	73	8	and	and	CC
cord-022561-rv5j1201	73	9	systemic	systemic	JJ
cord-022561-rv5j1201	73	10	control	control	NN
cord-022561-rv5j1201	73	11	and	and	CC
cord-022561-rv5j1201	73	12	responds	respond	VBZ
cord-022561-rv5j1201	73	13	rapidly	rapidly	RB
cord-022561-rv5j1201	73	14	and	and	CC
cord-022561-rv5j1201	73	15	predictably	predictably	RB
cord-022561-rv5j1201	73	16	to	to	IN
cord-022561-rv5j1201	73	17	various	various	JJ
cord-022561-rv5j1201	73	18	stimuli	stimulus	NNS
cord-022561-rv5j1201	73	19	.	.	.
cord-022561-rv5j1201	74	1	•	•	NNP
cord-022561-rv5j1201	75	1	Production	production	NN
cord-022561-rv5j1201	75	2	and	and	CC
cord-022561-rv5j1201	75	3	turnover	turnover	NN
cord-022561-rv5j1201	75	4	of	of	IN
cord-022561-rv5j1201	75	5	blood	blood	NN
cord-022561-rv5j1201	75	6	cells	cell	NNS
cord-022561-rv5j1201	75	7	are	be	VBP
cord-022561-rv5j1201	75	8	balanced	balanced	JJ
cord-022561-rv5j1201	75	9	so	so	IN
cord-022561-rv5j1201	75	10	that	that	IN
cord-022561-rv5j1201	75	11	numbers	number	NNS
cord-022561-rv5j1201	75	12	are	be	VBP
cord-022561-rv5j1201	75	13	maintained	maintain	VBN
cord-022561-rv5j1201	75	14	within	within	IN
cord-022561-rv5j1201	75	15	normal	normal	JJ
cord-022561-rv5j1201	75	16	ranges	range	NNS
cord-022561-rv5j1201	75	17	(	(	-LRB-
cord-022561-rv5j1201	75	18	steady	steady	JJ
cord-022561-rv5j1201	75	19	-	-	HYPH
cord-022561-rv5j1201	75	20	state	state	NN
cord-022561-rv5j1201	75	21	kinetics	kinetic	NNS
cord-022561-rv5j1201	75	22	)	)	-RRB-
cord-022561-rv5j1201	75	23	in	in	IN
cord-022561-rv5j1201	75	24	healthy	healthy	JJ
cord-022561-rv5j1201	75	25	individuals	individual	NNS
cord-022561-rv5j1201	75	26	.	.	.
cord-022561-rv5j1201	76	1	•	•	NNP
cord-022561-rv5j1201	77	1	Normally	normally	RB
cord-022561-rv5j1201	77	2	the	the	DT
cord-022561-rv5j1201	77	3	bone	bone	NN
cord-022561-rv5j1201	77	4	marrow	marrow	NN
cord-022561-rv5j1201	77	5	releases	release	VBZ
cord-022561-rv5j1201	77	6	mostly	mostly	RB
cord-022561-rv5j1201	77	7	mature	mature	JJ
cord-022561-rv5j1201	77	8	cell	cell	NN
cord-022561-rv5j1201	77	9	types	type	NNS
cord-022561-rv5j1201	77	10	(	(	-LRB-
cord-022561-rv5j1201	77	11	and	and	CC
cord-022561-rv5j1201	77	12	very	very	RB
cord-022561-rv5j1201	77	13	low	low	JJ
cord-022561-rv5j1201	77	14	numbers	number	NNS
cord-022561-rv5j1201	77	15	of	of	IN
cord-022561-rv5j1201	77	16	cells	cell	NNS
cord-022561-rv5j1201	77	17	that	that	WDT
cord-022561-rv5j1201	77	18	are	be	VBP
cord-022561-rv5j1201	77	19	almost	almost	RB
cord-022561-rv5j1201	77	20	fully	fully	RB
cord-022561-rv5j1201	77	21	mature	mature	JJ
cord-022561-rv5j1201	77	22	)	)	-RRB-
cord-022561-rv5j1201	77	23	into	into	IN
cord-022561-rv5j1201	77	24	the	the	DT
cord-022561-rv5j1201	77	25	circulation	circulation	NN
cord-022561-rv5j1201	77	26	.	.	.
cord-022561-rv5j1201	78	1	In	in	IN
cord-022561-rv5j1201	78	2	response	response	NN
cord-022561-rv5j1201	78	3	to	to	IN
cord-022561-rv5j1201	78	4	certain	certain	JJ
cord-022561-rv5j1201	78	5	physiologic	physiologic	JJ
cord-022561-rv5j1201	78	6	or	or	CC
cord-022561-rv5j1201	78	7	pathologic	pathologic	JJ
cord-022561-rv5j1201	78	8	stimuli	stimulus	NNS
cord-022561-rv5j1201	78	9	,	,	,
cord-022561-rv5j1201	78	10	however	however	RB
cord-022561-rv5j1201	78	11	,	,	,
cord-022561-rv5j1201	78	12	the	the	DT
cord-022561-rv5j1201	78	13	bone	bone	NN
cord-022561-rv5j1201	78	14	marrow	marrow	NN
cord-022561-rv5j1201	78	15	releases	release	VBZ
cord-022561-rv5j1201	78	16	immature	immature	JJ
cord-022561-rv5j1201	78	17	cells	cell	NNS
cord-022561-rv5j1201	78	18	that	that	WDT
cord-022561-rv5j1201	78	19	are	be	VBP
cord-022561-rv5j1201	78	20	further	further	RB
cord-022561-rv5j1201	78	21	back	back	RB
cord-022561-rv5j1201	78	22	in	in	IN
cord-022561-rv5j1201	78	23	the	the	DT
cord-022561-rv5j1201	78	24	supply	supply	NN
cord-022561-rv5j1201	78	25	"	"	''
cord-022561-rv5j1201	78	26	pipeline	pipeline	NN
cord-022561-rv5j1201	78	27	.	.	.
cord-022561-rv5j1201	79	1	"	"	''
cord-022561-rv5j1201	80	1	The	the	DT
cord-022561-rv5j1201	80	2	composition	composition	NN
cord-022561-rv5j1201	80	3	of	of	IN
cord-022561-rv5j1201	80	4	the	the	DT
cord-022561-rv5j1201	80	5	marrow	marrow	NN
cord-022561-rv5j1201	80	6	changes	change	NNS
cord-022561-rv5j1201	80	7	with	with	IN
cord-022561-rv5j1201	80	8	age	age	NN
cord-022561-rv5j1201	80	9	.	.	.
cord-022561-rv5j1201	81	1	The	the	DT
cord-022561-rv5j1201	81	2	general	general	JJ
cord-022561-rv5j1201	81	3	pattern	pattern	NN
cord-022561-rv5j1201	81	4	is	be	VBZ
cord-022561-rv5j1201	81	5	that	that	DT
cord-022561-rv5j1201	81	6	hematopoietic	hematopoietic	JJ
cord-022561-rv5j1201	81	7	tissue	tissue	NN
cord-022561-rv5j1201	81	8	(	(	-LRB-
cord-022561-rv5j1201	81	9	red	red	JJ
cord-022561-rv5j1201	81	10	marrow	marrow	NN
cord-022561-rv5j1201	81	11	)	)	-RRB-
cord-022561-rv5j1201	81	12	regresses	regress	VBZ
cord-022561-rv5j1201	81	13	and	and	CC
cord-022561-rv5j1201	81	14	is	be	VBZ
cord-022561-rv5j1201	81	15	replaced	replace	VBN
cord-022561-rv5j1201	81	16	with	with	IN
cord-022561-rv5j1201	81	17	nonhematopoietic	nonhematopoietic	JJ
cord-022561-rv5j1201	81	18	tissue	tissue	NN
cord-022561-rv5j1201	81	19	,	,	,
cord-022561-rv5j1201	81	20	mainly	mainly	RB
cord-022561-rv5j1201	81	21	fat	fat	JJ
cord-022561-rv5j1201	81	22	(	(	-LRB-
cord-022561-rv5j1201	81	23	yellow	yellow	JJ
cord-022561-rv5j1201	81	24	marrow	marrow	NN
cord-022561-rv5j1201	81	25	)	)	-RRB-
cord-022561-rv5j1201	81	26	.	.	.
cord-022561-rv5j1201	82	1	Thus	thus	RB
cord-022561-rv5j1201	82	2	in	in	IN
cord-022561-rv5j1201	82	3	newborns	newborn	NNS
cord-022561-rv5j1201	82	4	and	and	CC
cord-022561-rv5j1201	82	5	very	very	RB
cord-022561-rv5j1201	82	6	young	young	JJ
cord-022561-rv5j1201	82	7	animals	animal	NNS
cord-022561-rv5j1201	82	8	the	the	DT
cord-022561-rv5j1201	82	9	bone	bone	NN
cord-022561-rv5j1201	82	10	marrow	marrow	NN
cord-022561-rv5j1201	82	11	consists	consist	VBZ
cord-022561-rv5j1201	82	12	largely	largely	RB
cord-022561-rv5j1201	82	13	of	of	IN
cord-022561-rv5j1201	82	14	hematopoietically	hematopoietically	RB
cord-022561-rv5j1201	82	15	active	active	JJ
cord-022561-rv5j1201	82	16	tissue	tissue	NN
cord-022561-rv5j1201	82	17	,	,	,
cord-022561-rv5j1201	82	18	with	with	IN
cord-022561-rv5j1201	82	19	relatively	relatively	RB
cord-022561-rv5j1201	82	20	little	little	JJ
cord-022561-rv5j1201	82	21	fat	fat	NN
cord-022561-rv5j1201	82	22	,	,	,
cord-022561-rv5j1201	82	23	whereas	whereas	IN
cord-022561-rv5j1201	82	24	in	in	IN
cord-022561-rv5j1201	82	25	geriatric	geriatric	JJ
cord-022561-rv5j1201	82	26	individuals	individual	NNS
cord-022561-rv5j1201	82	27	the	the	DT
cord-022561-rv5j1201	82	28	marrow	marrow	NN
cord-022561-rv5j1201	82	29	consists	consist	VBZ
cord-022561-rv5j1201	82	30	largely	largely	RB
cord-022561-rv5j1201	82	31	of	of	IN
cord-022561-rv5j1201	82	32	fat	fat	NN
cord-022561-rv5j1201	82	33	.	.	.
cord-022561-rv5j1201	83	1	In	in	IN
cord-022561-rv5j1201	83	2	adults	adult	NNS
cord-022561-rv5j1201	83	3	,	,	,
cord-022561-rv5j1201	83	4	hematopoiesis	hematopoiesis	NN
cord-022561-rv5j1201	83	5	occurs	occur	VBZ
cord-022561-rv5j1201	83	6	primarily	primarily	RB
cord-022561-rv5j1201	83	7	in	in	IN
cord-022561-rv5j1201	83	8	the	the	DT
cord-022561-rv5j1201	83	9	pelvis	pelvi	NNS
cord-022561-rv5j1201	83	10	,	,	,
cord-022561-rv5j1201	83	11	sternum	sternum	NN
cord-022561-rv5j1201	83	12	,	,	,
cord-022561-rv5j1201	83	13	ribs	rib	NNS
cord-022561-rv5j1201	83	14	,	,	,
cord-022561-rv5j1201	83	15	vertebrae	vertebrae	NN
cord-022561-rv5j1201	83	16	,	,	,
cord-022561-rv5j1201	83	17	and	and	CC
cord-022561-rv5j1201	83	18	the	the	DT
cord-022561-rv5j1201	83	19	proximal	proximal	JJ
cord-022561-rv5j1201	83	20	ends	end	NNS
cord-022561-rv5j1201	83	21	of	of	IN
cord-022561-rv5j1201	83	22	humeri	humerus	NNS
cord-022561-rv5j1201	83	23	and	and	CC
cord-022561-rv5j1201	83	24	femora	femur	NNS
cord-022561-rv5j1201	83	25	.	.	.
cord-022561-rv5j1201	84	1	Even	even	RB
cord-022561-rv5j1201	84	2	within	within	IN
cord-022561-rv5j1201	84	3	these	these	DT
cord-022561-rv5j1201	84	4	areas	area	NNS
cord-022561-rv5j1201	84	5	of	of	IN
cord-022561-rv5j1201	84	6	active	active	JJ
cord-022561-rv5j1201	84	7	hematopoiesis	hematopoiesis	NN
cord-022561-rv5j1201	84	8	,	,	,
cord-022561-rv5j1201	84	9	fat	fat	JJ
cord-022561-rv5j1201	84	10	may	may	MD
cord-022561-rv5j1201	84	11	constitute	constitute	VB
cord-022561-rv5j1201	84	12	a	a	DT
cord-022561-rv5j1201	84	13	significant	significant	JJ
cord-022561-rv5j1201	84	14	proportion	proportion	NN
cord-022561-rv5j1201	84	15	of	of	IN
cord-022561-rv5j1201	84	16	the	the	DT
cord-022561-rv5j1201	84	17	marrow	marrow	NN
cord-022561-rv5j1201	84	18	volume	volume	NN
cord-022561-rv5j1201	84	19	.	.	.
cord-022561-rv5j1201	85	1	Immature	immature	JJ
cord-022561-rv5j1201	85	2	hematopoietic	hematopoietic	JJ
cord-022561-rv5j1201	85	3	cells	cell	NNS
cord-022561-rv5j1201	85	4	can	can	MD
cord-022561-rv5j1201	85	5	be	be	VB
cord-022561-rv5j1201	85	6	divided	divide	VBN
cord-022561-rv5j1201	85	7	into	into	IN
cord-022561-rv5j1201	85	8	three	three	CD
cord-022561-rv5j1201	85	9	stages	stage	NNS
cord-022561-rv5j1201	85	10	:	:	:
cord-022561-rv5j1201	85	11	stem	stem	NN
cord-022561-rv5j1201	85	12	cells	cell	NNS
cord-022561-rv5j1201	85	13	,	,	,
cord-022561-rv5j1201	85	14	progenitor	progenitor	NN
cord-022561-rv5j1201	85	15	cells	cell	NNS
cord-022561-rv5j1201	85	16	,	,	,
cord-022561-rv5j1201	85	17	and	and	CC
cord-022561-rv5j1201	85	18	precursor	precursor	NN
cord-022561-rv5j1201	85	19	cells	cell	NNS
cord-022561-rv5j1201	85	20	.	.	.
cord-022561-rv5j1201	86	1	Hematopoietic	hematopoietic	JJ
cord-022561-rv5j1201	86	2	stem	stem	NN
cord-022561-rv5j1201	86	3	cells	cell	NNS
cord-022561-rv5j1201	86	4	(	(	-LRB-
cord-022561-rv5j1201	86	5	HSCs	HSCs	NNP
cord-022561-rv5j1201	86	6	)	)	-RRB-
cord-022561-rv5j1201	86	7	have	have	VBP
cord-022561-rv5j1201	86	8	the	the	DT
cord-022561-rv5j1201	86	9	capacity	capacity	NN
cord-022561-rv5j1201	86	10	to	to	IN
cord-022561-rv5j1201	86	11	self	self	NN
cord-022561-rv5j1201	86	12	-	-	HYPH
cord-022561-rv5j1201	86	13	renew	renew	VB
cord-022561-rv5j1201	86	14	,	,	,
cord-022561-rv5j1201	86	15	differentiate	differentiate	VB
cord-022561-rv5j1201	86	16	into	into	IN
cord-022561-rv5j1201	86	17	mature	mature	JJ
cord-022561-rv5j1201	86	18	cells	cell	NNS
cord-022561-rv5j1201	86	19	,	,	,
cord-022561-rv5j1201	86	20	and	and	CC
cord-022561-rv5j1201	86	21	repopulate	repopulate	VB
cord-022561-rv5j1201	86	22	the	the	DT
cord-022561-rv5j1201	86	23	bone	bone	NN
cord-022561-rv5j1201	86	24	marrow	marrow	NN
cord-022561-rv5j1201	86	25	after	after	IN
cord-022561-rv5j1201	86	26	it	-PRON-	PRP
cord-022561-rv5j1201	86	27	is	be	VBZ
cord-022561-rv5j1201	86	28	obliterated	obliterate	VBN
cord-022561-rv5j1201	86	29	.	.	.
cord-022561-rv5j1201	87	1	Progenitor	progenitor	NN
cord-022561-rv5j1201	87	2	cells	cell	NNS
cord-022561-rv5j1201	87	3	and	and	CC
cord-022561-rv5j1201	87	4	precursor	precursor	NN
cord-022561-rv5j1201	87	5	cells	cell	NNS
cord-022561-rv5j1201	87	6	can	can	MD
cord-022561-rv5j1201	87	7	not	not	RB
cord-022561-rv5j1201	87	8	self	self	NN
cord-022561-rv5j1201	87	9	-	-	HYPH
cord-022561-rv5j1201	87	10	renew	renew	VB
cord-022561-rv5j1201	87	11	;	;	:
cord-022561-rv5j1201	87	12	with	with	IN
cord-022561-rv5j1201	87	13	each	each	DT
cord-022561-rv5j1201	87	14	cell	cell	NN
cord-022561-rv5j1201	87	15	division	division	NN
cord-022561-rv5j1201	87	16	,	,	,
cord-022561-rv5j1201	87	17	they	-PRON-	PRP
cord-022561-rv5j1201	87	18	evolve	evolve	VBP
cord-022561-rv5j1201	87	19	into	into	IN
cord-022561-rv5j1201	87	20	more	more	RBR
cord-022561-rv5j1201	87	21	differentiated	differentiated	JJ
cord-022561-rv5j1201	87	22	cells	cell	NNS
cord-022561-rv5j1201	87	23	.	.	.
cord-022561-rv5j1201	88	1	Later	later	JJ
cord-022561-rv5j1201	88	2	-	-	HYPH
cord-022561-rv5j1201	88	3	stage	stage	NN
cord-022561-rv5j1201	88	4	precursors	precursor	NNS
cord-022561-rv5j1201	88	5	can	can	MD
cord-022561-rv5j1201	88	6	not	not	RB
cord-022561-rv5j1201	88	7	divide	divide	VB
cord-022561-rv5j1201	88	8	.	.	.
cord-022561-rv5j1201	89	1	Stem	stem	NN
cord-022561-rv5j1201	89	2	cells	cell	NNS
cord-022561-rv5j1201	89	3	and	and	CC
cord-022561-rv5j1201	89	4	progenitor	progenitor	NN
cord-022561-rv5j1201	89	5	cells	cell	NNS
cord-022561-rv5j1201	89	6	require	require	VBP
cord-022561-rv5j1201	89	7	immunochemical	immunochemical	JJ
cord-022561-rv5j1201	89	8	stains	stain	NNS
cord-022561-rv5j1201	89	9	for	for	IN
cord-022561-rv5j1201	89	10	identification	identification	NN
cord-022561-rv5j1201	89	11	,	,	,
cord-022561-rv5j1201	89	12	but	but	CC
cord-022561-rv5j1201	89	13	precursor	precursor	NN
cord-022561-rv5j1201	89	14	cells	cell	NNS
cord-022561-rv5j1201	89	15	can	can	MD
cord-022561-rv5j1201	89	16	be	be	VB
cord-022561-rv5j1201	89	17	identified	identify	VBN
cord-022561-rv5j1201	89	18	by	by	IN
cord-022561-rv5j1201	89	19	their	-PRON-	PRP$
cord-022561-rv5j1201	89	20	characteristic	characteristic	JJ
cord-022561-rv5j1201	89	21	morphologic	morphologic	JJ
cord-022561-rv5j1201	89	22	features	feature	NNS
cord-022561-rv5j1201	89	23	(	(	-LRB-
cord-022561-rv5j1201	89	24	see	see	VB
cord-022561-rv5j1201	89	25	Fig	Fig	NNP
cord-022561-rv5j1201	89	26	.	.	.
cord-022561-rv5j1201	90	1	13	13	CD
cord-022561-rv5j1201	90	2	-3	-3	NNP
cord-022561-rv5j1201	90	3	)	)	-RRB-
cord-022561-rv5j1201	90	4	.	.	.
cord-022561-rv5j1201	91	1	Control	Control	NNP
cord-022561-rv5j1201	91	2	of	of	IN
cord-022561-rv5j1201	91	3	hematopoiesis	hematopoiesis	NNP
cord-022561-rv5j1201	91	4	is	be	VBZ
cord-022561-rv5j1201	91	5	complex	complex	JJ
cord-022561-rv5j1201	91	6	,	,	,
cord-022561-rv5j1201	91	7	with	with	IN
cord-022561-rv5j1201	91	8	many	many	JJ
cord-022561-rv5j1201	91	9	redundancies	redundancy	NNS
cord-022561-rv5j1201	91	10	,	,	,
cord-022561-rv5j1201	91	11	feedback	feedback	NN
cord-022561-rv5j1201	91	12	mechanisms	mechanism	NNS
cord-022561-rv5j1201	91	13	,	,	,
cord-022561-rv5j1201	91	14	and	and	CC
cord-022561-rv5j1201	91	15	pathways	pathway	NNS
cord-022561-rv5j1201	91	16	that	that	WDT
cord-022561-rv5j1201	91	17	overlap	overlap	VBP
cord-022561-rv5j1201	91	18	with	with	IN
cord-022561-rv5j1201	91	19	other	other	JJ
cord-022561-rv5j1201	91	20	physiologic	physiologic	JJ
cord-022561-rv5j1201	91	21	and	and	CC
cord-022561-rv5j1201	91	22	pathologic	pathologic	JJ
cord-022561-rv5j1201	91	23	processes	process	NNS
cord-022561-rv5j1201	91	24	.	.	.
cord-022561-rv5j1201	92	1	Many	many	JJ
cord-022561-rv5j1201	92	2	cytokines	cytokine	NNS
cord-022561-rv5j1201	92	3	influence	influence	NN
cord-022561-rv5j1201	92	4	cells	cell	NNS
cord-022561-rv5j1201	92	5	of	of	IN
cord-022561-rv5j1201	92	6	different	different	JJ
cord-022561-rv5j1201	92	7	lineages	lineage	NNS
cord-022561-rv5j1201	92	8	and	and	CC
cord-022561-rv5j1201	92	9	stages	stage	NNS
cord-022561-rv5j1201	92	10	of	of	IN
cord-022561-rv5j1201	92	11	differentiation	differentiation	NN
cord-022561-rv5j1201	92	12	.	.	.
cord-022561-rv5j1201	93	1	Primary	primary	JJ
cord-022561-rv5j1201	93	2	growth	growth	NN
cord-022561-rv5j1201	93	3	factors	factor	NNS
cord-022561-rv5j1201	93	4	for	for	IN
cord-022561-rv5j1201	93	5	primitive	primitive	JJ
cord-022561-rv5j1201	93	6	cells	cell	NNS
cord-022561-rv5j1201	93	7	are	be	VBP
cord-022561-rv5j1201	93	8	interleukin	interleukin	JJ
cord-022561-rv5j1201	93	9	(	(	-LRB-
cord-022561-rv5j1201	93	10	IL	IL	NNP
cord-022561-rv5j1201	93	11	)	)	-RRB-
cord-022561-rv5j1201	93	12	3	3	CD
cord-022561-rv5j1201	93	13	,	,	,
cord-022561-rv5j1201	93	14	produced	produce	VBN
cord-022561-rv5j1201	93	15	by	by	IN
cord-022561-rv5j1201	93	16	T	T	NNP
cord-022561-rv5j1201	93	17	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	93	18	,	,	,
cord-022561-rv5j1201	93	19	and	and	CC
cord-022561-rv5j1201	93	20	stem	stem	NN
cord-022561-rv5j1201	93	21	cell	cell	NN
cord-022561-rv5j1201	93	22	factor	factor	NN
cord-022561-rv5j1201	93	23	,	,	,
cord-022561-rv5j1201	93	24	produced	produce	VBN
cord-022561-rv5j1201	93	25	by	by	IN
cord-022561-rv5j1201	93	26	monocytes	monocyte	NNS
cord-022561-rv5j1201	93	27	,	,	,
cord-022561-rv5j1201	93	28	macrophages	macrophage	NNS
cord-022561-rv5j1201	93	29	,	,	,
cord-022561-rv5j1201	93	30	fibroblasts	fibroblast	NNS
cord-022561-rv5j1201	93	31	,	,	,
cord-022561-rv5j1201	93	32	endothelial	endothelial	JJ
cord-022561-rv5j1201	93	33	cells	cell	NNS
cord-022561-rv5j1201	93	34	,	,	,
cord-022561-rv5j1201	93	35	and	and	CC
cord-022561-rv5j1201	93	36	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	93	37	.	.	.
cord-022561-rv5j1201	94	1	Interleukin	Interleukin	NNP
cord-022561-rv5j1201	94	2	7	7	CD
cord-022561-rv5j1201	94	3	is	be	VBZ
cord-022561-rv5j1201	94	4	an	an	DT
cord-022561-rv5j1201	94	5	early	early	JJ
cord-022561-rv5j1201	94	6	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	94	7	growth	growth	NN
cord-022561-rv5j1201	94	8	factor	factor	NN
cord-022561-rv5j1201	94	9	.	.	.
cord-022561-rv5j1201	95	1	Lineage	lineage	NN
cord-022561-rv5j1201	95	2	-	-	HYPH
cord-022561-rv5j1201	95	3	specific	specific	JJ
cord-022561-rv5j1201	95	4	growth	growth	NN
cord-022561-rv5j1201	95	5	factors	factor	NNS
cord-022561-rv5j1201	95	6	are	be	VBP
cord-022561-rv5j1201	95	7	discussed	discuss	VBN
cord-022561-rv5j1201	95	8	in	in	IN
cord-022561-rv5j1201	95	9	their	-PRON-	PRP$
cord-022561-rv5j1201	95	10	corresponding	corresponding	JJ
cord-022561-rv5j1201	95	11	sections	section	NNS
cord-022561-rv5j1201	95	12	.	.	.
cord-022561-rv5j1201	96	1	Hematopoiesis	hematopoiesis	NN
cord-022561-rv5j1201	96	2	occurs	occur	VBZ
cord-022561-rv5j1201	96	3	in	in	IN
cord-022561-rv5j1201	96	4	the	the	DT
cord-022561-rv5j1201	96	5	interstitium	interstitium	NN
cord-022561-rv5j1201	96	6	between	between	IN
cord-022561-rv5j1201	96	7	the	the	DT
cord-022561-rv5j1201	96	8	venous	venous	JJ
cord-022561-rv5j1201	96	9	sinusoids	sinusoid	NNS
cord-022561-rv5j1201	96	10	in	in	IN
cord-022561-rv5j1201	96	11	the	the	DT
cord-022561-rv5j1201	96	12	so	so	RB
cord-022561-rv5j1201	96	13	-	-	HYPH
cord-022561-rv5j1201	96	14	called	call	VBN
cord-022561-rv5j1201	96	15	hematopoietic	hematopoietic	JJ
cord-022561-rv5j1201	96	16	spaces	space	NNS
cord-022561-rv5j1201	96	17	.	.	.
cord-022561-rv5j1201	97	1	There	there	EX
cord-022561-rv5j1201	97	2	is	be	VBZ
cord-022561-rv5j1201	97	3	a	a	DT
cord-022561-rv5j1201	97	4	complex	complex	JJ
cord-022561-rv5j1201	97	5	functional	functional	JJ
cord-022561-rv5j1201	97	6	interplay	interplay	NN
cord-022561-rv5j1201	97	7	among	among	IN
cord-022561-rv5j1201	97	8	hematopoietic	hematopoietic	JJ
cord-022561-rv5j1201	97	9	cells	cell	NNS
cord-022561-rv5j1201	97	10	with	with	IN
cord-022561-rv5j1201	97	11	the	the	DT
cord-022561-rv5j1201	97	12	supporting	support	VBG
cord-022561-rv5j1201	97	13	connective	connective	JJ
cord-022561-rv5j1201	97	14	tissue	tissue	NN
cord-022561-rv5j1201	97	15	cells	cell	NNS
cord-022561-rv5j1201	97	16	,	,	,
cord-022561-rv5j1201	97	17	extracellular	extracellular	JJ
cord-022561-rv5j1201	97	18	matrix	matrix	NN
cord-022561-rv5j1201	97	19	,	,	,
cord-022561-rv5j1201	97	20	and	and	CC
cord-022561-rv5j1201	97	21	soluble	soluble	JJ
cord-022561-rv5j1201	97	22	factors	factor	NNS
cord-022561-rv5j1201	97	23	,	,	,
cord-022561-rv5j1201	97	24	which	which	WDT
cord-022561-rv5j1201	97	25	form	form	VBP
cord-022561-rv5j1201	97	26	the	the	DT
cord-022561-rv5j1201	97	27	hematopoietic	hematopoietic	JJ
cord-022561-rv5j1201	97	28	microenvironment	microenvironment	NN
cord-022561-rv5j1201	97	29	.	.	.
cord-022561-rv5j1201	98	1	Behavior	behavior	NN
cord-022561-rv5j1201	98	2	of	of	IN
cord-022561-rv5j1201	98	3	hematopoietic	hematopoietic	JJ
cord-022561-rv5j1201	98	4	cells	cell	NNS
cord-022561-rv5j1201	98	5	is	be	VBZ
cord-022561-rv5j1201	98	6	influenced	influence	VBN
cord-022561-rv5j1201	98	7	by	by	IN
cord-022561-rv5j1201	98	8	direct	direct	JJ
cord-022561-rv5j1201	98	9	cell	cell	NN
cord-022561-rv5j1201	98	10	-	-	HYPH
cord-022561-rv5j1201	98	11	to	to	IN
cord-022561-rv5j1201	98	12	-	-	HYPH
cord-022561-rv5j1201	98	13	cell	cell	NN
cord-022561-rv5j1201	98	14	and	and	CC
cord-022561-rv5j1201	98	15	cellmatrix	cellmatrix	VB
cord-022561-rv5j1201	98	16	interactions	interaction	NNS
cord-022561-rv5j1201	98	17	and	and	CC
cord-022561-rv5j1201	98	18	by	by	IN
cord-022561-rv5j1201	98	19	soluble	soluble	JJ
cord-022561-rv5j1201	98	20	mediators	mediator	NNS
cord-022561-rv5j1201	98	21	,	,	,
cord-022561-rv5j1201	98	22	such	such	JJ
cord-022561-rv5j1201	98	23	as	as	IN
cord-022561-rv5j1201	98	24	cytokines	cytokine	NNS
cord-022561-rv5j1201	98	25	and	and	CC
cord-022561-rv5j1201	98	26	hormones	hormone	NNS
cord-022561-rv5j1201	98	27	that	that	WDT
cord-022561-rv5j1201	98	28	interact	interact	VBP
cord-022561-rv5j1201	98	29	with	with	IN
cord-022561-rv5j1201	98	30	cells	cell	NNS
cord-022561-rv5j1201	98	31	and	and	CC
cord-022561-rv5j1201	98	32	with	with	IN
cord-022561-rv5j1201	98	33	matrix	matrix	NN
cord-022561-rv5j1201	98	34	proteins	protein	NNS
cord-022561-rv5j1201	98	35	.	.	.
cord-022561-rv5j1201	99	1	Cells	cell	NNS
cord-022561-rv5j1201	99	2	localize	localize	VBP
cord-022561-rv5j1201	99	3	to	to	IN
cord-022561-rv5j1201	99	4	specific	specific	JJ
cord-022561-rv5j1201	99	5	niches	niche	NNS
cord-022561-rv5j1201	99	6	within	within	IN
cord-022561-rv5j1201	99	7	the	the	DT
cord-022561-rv5j1201	99	8	hematopoietic	hematopoietic	JJ
cord-022561-rv5j1201	99	9	microenvironment	microenvironment	NN
cord-022561-rv5j1201	99	10	via	via	IN
cord-022561-rv5j1201	99	11	adhesion	adhesion	NN
cord-022561-rv5j1201	99	12	molecules	molecule	NNS
cord-022561-rv5j1201	99	13	,	,	,
cord-022561-rv5j1201	99	14	such	such	JJ
cord-022561-rv5j1201	99	15	as	as	IN
cord-022561-rv5j1201	99	16	integrins	integrin	NNS
cord-022561-rv5j1201	99	17	,	,	,
cord-022561-rv5j1201	99	18	immunoglobulins	immunoglobulin	NNS
cord-022561-rv5j1201	99	19	,	,	,
cord-022561-rv5j1201	99	20	lectins	lectin	NNS
cord-022561-rv5j1201	99	21	,	,	,
cord-022561-rv5j1201	99	22	and	and	CC
cord-022561-rv5j1201	99	23	other	other	JJ
cord-022561-rv5j1201	99	24	receptors	receptor	NNS
cord-022561-rv5j1201	99	25	,	,	,
cord-022561-rv5j1201	99	26	which	which	WDT
cord-022561-rv5j1201	99	27	recognize	recognize	VBP
cord-022561-rv5j1201	99	28	ligands	ligand	NNS
cord-022561-rv5j1201	99	29	on	on	IN
cord-022561-rv5j1201	99	30	other	other	JJ
cord-022561-rv5j1201	99	31	cells	cell	NNS
cord-022561-rv5j1201	99	32	or	or	CC
cord-022561-rv5j1201	99	33	matrix	matrix	NN
cord-022561-rv5j1201	99	34	components	component	NNS
cord-022561-rv5j1201	99	35	.	.	.
cord-022561-rv5j1201	100	1	Cells	cell	NNS
cord-022561-rv5j1201	100	2	also	also	RB
cord-022561-rv5j1201	100	3	express	express	VBP
cord-022561-rv5j1201	100	4	receptors	receptor	NNS
cord-022561-rv5j1201	100	5	for	for	IN
cord-022561-rv5j1201	100	6	soluble	soluble	JJ
cord-022561-rv5j1201	100	7	molecules	molecule	NNS
cord-022561-rv5j1201	100	8	such	such	JJ
cord-022561-rv5j1201	100	9	as	as	IN
cord-022561-rv5j1201	100	10	chemokines	chemokine	NNS
cord-022561-rv5j1201	100	11	(	(	-LRB-
cord-022561-rv5j1201	100	12	chemoattractant	chemoattractant	NN
cord-022561-rv5j1201	100	13	cytokines	cytokine	NNS
cord-022561-rv5j1201	100	14	)	)	-RRB-
cord-022561-rv5j1201	100	15	and	and	CC
cord-022561-rv5j1201	100	16	hormones	hormone	NNS
cord-022561-rv5j1201	100	17	that	that	WDT
cord-022561-rv5j1201	100	18	influence	influence	VBP
cord-022561-rv5j1201	100	19	cell	cell	NN
cord-022561-rv5j1201	100	20	trafficking	trafficking	NN
cord-022561-rv5j1201	100	21	and	and	CC
cord-022561-rv5j1201	100	22	metabolism	metabolism	NN
cord-022561-rv5j1201	100	23	.	.	.
cord-022561-rv5j1201	101	1	Iron	iron	NN
cord-022561-rv5j1201	101	2	is	be	VBZ
cord-022561-rv5j1201	101	3	essential	essential	JJ
cord-022561-rv5j1201	101	4	to	to	IN
cord-022561-rv5j1201	101	5	hemoglobin	hemoglobin	NN
cord-022561-rv5j1201	101	6	synthesis	synthesis	NN
cord-022561-rv5j1201	101	7	and	and	CC
cord-022561-rv5j1201	101	8	function	function	NN
cord-022561-rv5j1201	101	9	.	.	.
cord-022561-rv5j1201	102	1	It	-PRON-	PRP
cord-022561-rv5j1201	102	2	is	be	VBZ
cord-022561-rv5j1201	102	3	acquired	acquire	VBN
cord-022561-rv5j1201	102	4	through	through	IN
cord-022561-rv5j1201	102	5	the	the	DT
cord-022561-rv5j1201	102	6	diet	diet	NN
cord-022561-rv5j1201	102	7	and	and	CC
cord-022561-rv5j1201	102	8	is	be	VBZ
cord-022561-rv5j1201	102	9	transported	transport	VBN
cord-022561-rv5j1201	102	10	to	to	IN
cord-022561-rv5j1201	102	11	the	the	DT
cord-022561-rv5j1201	102	12	bone	bone	NN
cord-022561-rv5j1201	102	13	marrow	marrow	NN
cord-022561-rv5j1201	102	14	via	via	IN
cord-022561-rv5j1201	102	15	the	the	DT
cord-022561-rv5j1201	102	16	iron	iron	NN
cord-022561-rv5j1201	102	17	transport	transport	NN
cord-022561-rv5j1201	102	18	protein	protein	NN
cord-022561-rv5j1201	102	19	,	,	,
cord-022561-rv5j1201	102	20	transferrin	transferrin	NN
cord-022561-rv5j1201	102	21	.	.	.
cord-022561-rv5j1201	103	1	Central	central	JJ
cord-022561-rv5j1201	103	2	macrophages	macrophage	NNS
cord-022561-rv5j1201	103	3	either	either	CC
cord-022561-rv5j1201	103	4	store	store	NN
cord-022561-rv5j1201	103	5	iron	iron	NN
cord-022561-rv5j1201	103	6	as	as	IN
cord-022561-rv5j1201	103	7	ferritin	ferritin	NN
cord-022561-rv5j1201	103	8	or	or	CC
cord-022561-rv5j1201	103	9	hemosiderin	hemosiderin	NNP
cord-022561-rv5j1201	103	10	,	,	,
cord-022561-rv5j1201	103	11	or	or	CC
cord-022561-rv5j1201	103	12	transfer	transfer	VB
cord-022561-rv5j1201	103	13	the	the	DT
cord-022561-rv5j1201	103	14	iron	iron	NN
cord-022561-rv5j1201	103	15	to	to	IN
cord-022561-rv5j1201	103	16	erythroid	erythroid	JJ
cord-022561-rv5j1201	103	17	precursors	precursor	NNS
cord-022561-rv5j1201	103	18	for	for	IN
cord-022561-rv5j1201	103	19	hemoglobin	hemoglobin	NN
cord-022561-rv5j1201	103	20	synthesis	synthesis	NN
cord-022561-rv5j1201	103	21	.	.	.
cord-022561-rv5j1201	104	1	Hemosiderin	Hemosiderin	NNP
cord-022561-rv5j1201	104	2	is	be	VBZ
cord-022561-rv5j1201	104	3	identifiable	identifiable	JJ
cord-022561-rv5j1201	104	4	in	in	IN
cord-022561-rv5j1201	104	5	routinely	routinely	RB
cord-022561-rv5j1201	104	6	stained	stain	VBN
cord-022561-rv5j1201	104	7	marrow	marrow	NN
cord-022561-rv5j1201	104	8	preparations	preparation	NNS
cord-022561-rv5j1201	104	9	as	as	IN
cord-022561-rv5j1201	104	10	an	an	DT
cord-022561-rv5j1201	104	11	intracellular	intracellular	JJ
cord-022561-rv5j1201	104	12	brown	brown	JJ
cord-022561-rv5j1201	104	13	pigment	pigment	NN
cord-022561-rv5j1201	104	14	.	.	.
cord-022561-rv5j1201	105	1	However	however	RB
cord-022561-rv5j1201	105	2	,	,	,
cord-022561-rv5j1201	105	3	Perls	Perls	NNP
cord-022561-rv5j1201	105	4	's	's	POS
cord-022561-rv5j1201	105	5	Prussian	prussian	JJ
cord-022561-rv5j1201	105	6	blue	blue	JJ
cord-022561-rv5j1201	105	7	stain	stain	NN
cord-022561-rv5j1201	105	8	is	be	VBZ
cord-022561-rv5j1201	105	9	more	more	RBR
cord-022561-rv5j1201	105	10	sensitive	sensitive	JJ
cord-022561-rv5j1201	105	11	and	and	CC
cord-022561-rv5j1201	105	12	specific	specific	JJ
cord-022561-rv5j1201	105	13	for	for	IN
cord-022561-rv5j1201	105	14	iron	iron	NN
cord-022561-rv5j1201	105	15	detection	detection	NN
cord-022561-rv5j1201	105	16	.	.	.
cord-022561-rv5j1201	106	1	The	the	DT
cord-022561-rv5j1201	106	2	earliest	early	JJS
cord-022561-rv5j1201	106	3	erythroid	erythroid	NN
cord-022561-rv5j1201	106	4	precursor	precursor	NN
cord-022561-rv5j1201	106	5	identifiable	identifiable	JJ
cord-022561-rv5j1201	106	6	by	by	IN
cord-022561-rv5j1201	106	7	routine	routine	JJ
cord-022561-rv5j1201	106	8	light	light	JJ
cord-022561-rv5j1201	106	9	microscopy	microscopy	NN
cord-022561-rv5j1201	106	10	is	be	VBZ
cord-022561-rv5j1201	106	11	the	the	DT
cord-022561-rv5j1201	106	12	rubriblast	rubriblast	NN
cord-022561-rv5j1201	106	13	,	,	,
cord-022561-rv5j1201	106	14	which	which	WDT
cord-022561-rv5j1201	106	15	undergoes	undergo	VBZ
cord-022561-rv5j1201	106	16	maturational	maturational	JJ
cord-022561-rv5j1201	106	17	division	division	NN
cord-022561-rv5j1201	106	18	to	to	TO
cord-022561-rv5j1201	106	19	produce	produce	VB
cord-022561-rv5j1201	106	20	8	8	CD
cord-022561-rv5j1201	106	21	to	to	TO
cord-022561-rv5j1201	106	22	32	32	CD
cord-022561-rv5j1201	106	23	progeny	progeny	NN
cord-022561-rv5j1201	106	24	cells	cell	NNS
cord-022561-rv5j1201	106	25	.	.	.
cord-022561-rv5j1201	107	1	Late	late	JJ
cord-022561-rv5j1201	107	2	-	-	HYPH
cord-022561-rv5j1201	107	3	stage	stage	NN
cord-022561-rv5j1201	107	4	erythroid	erythroid	NN
cord-022561-rv5j1201	107	5	precursors	precursor	NNS
cord-022561-rv5j1201	107	6	,	,	,
cord-022561-rv5j1201	107	7	known	know	VBN
cord-022561-rv5j1201	107	8	as	as	IN
cord-022561-rv5j1201	107	9	metarubricytes	metarubricyte	NNS
cord-022561-rv5j1201	107	10	,	,	,
cord-022561-rv5j1201	107	11	extrude	extrude	VB
cord-022561-rv5j1201	107	12	their	-PRON-	PRP$
cord-022561-rv5j1201	107	13	nuclei	nucleus	NNS
cord-022561-rv5j1201	107	14	and	and	CC
cord-022561-rv5j1201	107	15	become	become	VB
cord-022561-rv5j1201	107	16	inhibiting	inhibit	VBG
cord-022561-rv5j1201	107	17	apoptosis	apoptosis	NN
cord-022561-rv5j1201	107	18	of	of	IN
cord-022561-rv5j1201	107	19	developing	develop	VBG
cord-022561-rv5j1201	107	20	erythroid	erythroid	NN
cord-022561-rv5j1201	107	21	cells	cell	NNS
cord-022561-rv5j1201	107	22	.	.	.
cord-022561-rv5j1201	108	1	The	the	DT
cord-022561-rv5j1201	108	2	stimulus	stimulus	NN
cord-022561-rv5j1201	108	3	for	for	IN
cord-022561-rv5j1201	108	4	increased	increase	VBN
cord-022561-rv5j1201	108	5	Epo	Epo	NNP
cord-022561-rv5j1201	108	6	production	production	NN
cord-022561-rv5j1201	108	7	is	be	VBZ
cord-022561-rv5j1201	108	8	hypoxia	hypoxia	NN
cord-022561-rv5j1201	108	9	.	.	.
cord-022561-rv5j1201	109	1	Within	within	IN
cord-022561-rv5j1201	109	2	the	the	DT
cord-022561-rv5j1201	109	3	bone	bone	NN
cord-022561-rv5j1201	109	4	marrow	marrow	NN
cord-022561-rv5j1201	109	5	,	,	,
cord-022561-rv5j1201	109	6	erythroid	erythroid	NN
cord-022561-rv5j1201	109	7	precursors	precursor	NNS
cord-022561-rv5j1201	109	8	surround	surround	VBP
cord-022561-rv5j1201	109	9	a	a	DT
cord-022561-rv5j1201	109	10	central	central	JJ
cord-022561-rv5j1201	109	11	macrophage	macrophage	NN
cord-022561-rv5j1201	109	12	in	in	IN
cord-022561-rv5j1201	109	13	specialized	specialized	JJ
cord-022561-rv5j1201	109	14	niches	niche	NNS
cord-022561-rv5j1201	109	15	,	,	,
cord-022561-rv5j1201	109	16	termed	term	VBD
cord-022561-rv5j1201	109	17	erythroblastic	erythroblastic	JJ
cord-022561-rv5j1201	109	18	islands	island	NNS
cord-022561-rv5j1201	109	19	.	.	.
cord-022561-rv5j1201	110	1	The	the	DT
cord-022561-rv5j1201	110	2	central	central	JJ
cord-022561-rv5j1201	110	3	macrophage	macrophage	NN
cord-022561-rv5j1201	110	4	,	,	,
cord-022561-rv5j1201	110	5	also	also	RB
cord-022561-rv5j1201	110	6	known	know	VBN
cord-022561-rv5j1201	110	7	as	as	IN
cord-022561-rv5j1201	110	8	a	a	DT
cord-022561-rv5j1201	110	9	nurse	nurse	NN
cord-022561-rv5j1201	110	10	cell	cell	NN
cord-022561-rv5j1201	110	11	,	,	,
cord-022561-rv5j1201	110	12	anchors	anchor	NNS
cord-022561-rv5j1201	110	13	the	the	DT
cord-022561-rv5j1201	110	14	precursors	precursor	NNS
cord-022561-rv5j1201	110	15	within	within	IN
cord-022561-rv5j1201	110	16	the	the	DT
cord-022561-rv5j1201	110	17	island	island	NN
cord-022561-rv5j1201	110	18	niche	niche	NN
cord-022561-rv5j1201	110	19	,	,	,
cord-022561-rv5j1201	110	20	regulates	regulate	VBZ
cord-022561-rv5j1201	110	21	erythroid	erythroid	JJ
cord-022561-rv5j1201	110	22	proliferation	proliferation	NN
cord-022561-rv5j1201	110	23	and	and	CC
cord-022561-rv5j1201	110	24	differentiation	differentiation	NN
cord-022561-rv5j1201	110	25	,	,	,
cord-022561-rv5j1201	110	26	transfers	transfer	VBZ
cord-022561-rv5j1201	110	27	iron	iron	NN
cord-022561-rv5j1201	110	28	to	to	IN
cord-022561-rv5j1201	110	29	the	the	DT
cord-022561-rv5j1201	110	30	erythroid	erythroid	JJ
cord-022561-rv5j1201	110	31	progenitors	progenitor	NNS
cord-022561-rv5j1201	110	32	for	for	IN
cord-022561-rv5j1201	110	33	hemoglobin	hemoglobin	NN
cord-022561-rv5j1201	110	34	synthesis	synthesis	NN
cord-022561-rv5j1201	110	35	,	,	,
cord-022561-rv5j1201	110	36	and	and	CC
cord-022561-rv5j1201	110	37	phagocytizes	phagocytizes	NNP
cord-022561-rv5j1201	110	38	extruded	extrude	VBN
cord-022561-rv5j1201	110	39	metarubricyte	metarubricyte	NNP
cord-022561-rv5j1201	110	40	nuclei	nucleus	NNS
cord-022561-rv5j1201	110	41	.	.	.
cord-022561-rv5j1201	111	1	Although	although	IN
cord-022561-rv5j1201	111	2	erythroblastic	erythroblastic	JJ
cord-022561-rv5j1201	111	3	islands	island	NNS
cord-022561-rv5j1201	111	4	occur	occur	VBP
cord-022561-rv5j1201	111	5	throughout	throughout	IN
cord-022561-rv5j1201	111	6	the	the	DT
cord-022561-rv5j1201	111	7	marrow	marrow	NN
cord-022561-rv5j1201	111	8	,	,	,
cord-022561-rv5j1201	111	9	those	those	DT
cord-022561-rv5j1201	111	10	with	with	IN
cord-022561-rv5j1201	111	11	more	more	RBR
cord-022561-rv5j1201	111	12	differentiated	differentiated	JJ
cord-022561-rv5j1201	111	13	erythroid	erythroid	JJ
cord-022561-rv5j1201	111	14	cells	cell	NNS
cord-022561-rv5j1201	111	15	neighbor	neighbor	NN
cord-022561-rv5j1201	111	16	sinusoids	sinusoid	NNS
cord-022561-rv5j1201	111	17	,	,	,
cord-022561-rv5j1201	111	18	whereas	whereas	IN
cord-022561-rv5j1201	111	19	nonadjacent	nonadjacent	JJ
cord-022561-rv5j1201	111	20	islands	island	NNS
cord-022561-rv5j1201	111	21	contain	contain	VBP
cord-022561-rv5j1201	111	22	mostly	mostly	RB
cord-022561-rv5j1201	111	23	undifferentiated	undifferentiated	JJ
cord-022561-rv5j1201	111	24	precursors	precursor	NNS
cord-022561-rv5j1201	111	25	.	.	.
cord-022561-rv5j1201	112	1	As	as	IN
cord-022561-rv5j1201	112	2	erythroid	erythroid	NN
cord-022561-rv5j1201	112	3	cells	cell	NNS
cord-022561-rv5j1201	112	4	mature	mature	VBP
cord-022561-rv5j1201	112	5	from	from	IN
cord-022561-rv5j1201	112	6	a	a	DT
cord-022561-rv5j1201	112	7	rubriblast	rubriblast	NN
cord-022561-rv5j1201	112	8	to	to	IN
cord-022561-rv5j1201	112	9	a	a	DT
cord-022561-rv5j1201	112	10	mature	mature	JJ
cord-022561-rv5j1201	112	11	erythrocyte	erythrocyte	NN
cord-022561-rv5j1201	112	12	,	,	,
cord-022561-rv5j1201	112	13	their	-PRON-	PRP$
cord-022561-rv5j1201	112	14	nuclei	nucleus	NNS
cord-022561-rv5j1201	112	15	become	become	VBP
cord-022561-rv5j1201	112	16	smaller	small	JJR
cord-022561-rv5j1201	112	17	and	and	CC
cord-022561-rv5j1201	112	18	more	more	RBR
cord-022561-rv5j1201	112	19	condensed	condensed	JJ
cord-022561-rv5j1201	112	20	.	.	.
cord-022561-rv5j1201	113	1	The	the	DT
cord-022561-rv5j1201	113	2	nucleus	nucleus	NN
cord-022561-rv5j1201	113	3	is	be	VBZ
cord-022561-rv5j1201	113	4	eventually	eventually	RB
cord-022561-rv5j1201	113	5	extruded	extrude	VBN
cord-022561-rv5j1201	113	6	to	to	TO
cord-022561-rv5j1201	113	7	form	form	VB
cord-022561-rv5j1201	113	8	a	a	DT
cord-022561-rv5j1201	113	9	polychromatophil	polychromatophil	NN
cord-022561-rv5j1201	113	10	.	.	.
cord-022561-rv5j1201	114	1	Erythroid	Erythroid	NNP
cord-022561-rv5j1201	114	2	cells	cell	NNS
cord-022561-rv5j1201	114	3	also	also	RB
cord-022561-rv5j1201	114	4	become	become	VBP
cord-022561-rv5j1201	114	5	less	less	RBR
cord-022561-rv5j1201	114	6	basophilic	basophilic	JJ
cord-022561-rv5j1201	114	7	and	and	CC
cord-022561-rv5j1201	114	8	more	more	RBR
cord-022561-rv5j1201	114	9	eosinophilic	eosinophilic	JJ
cord-022561-rv5j1201	114	10	as	as	IN
cord-022561-rv5j1201	114	11	more	more	JJR
cord-022561-rv5j1201	114	12	hemoglobin	hemoglobin	NN
cord-022561-rv5j1201	114	13	is	be	VBZ
cord-022561-rv5j1201	114	14	produced	produce	VBN
cord-022561-rv5j1201	114	15	and	and	CC
cord-022561-rv5j1201	114	16	as	as	IN
cord-022561-rv5j1201	114	17	RNA	rna	NN
cord-022561-rv5j1201	114	18	-	-	HYPH
cord-022561-rv5j1201	114	19	rich	rich	JJ
cord-022561-rv5j1201	114	20	organelles	organelle	NNS
cord-022561-rv5j1201	114	21	are	be	VBP
cord-022561-rv5j1201	114	22	lost	lose	VBN
cord-022561-rv5j1201	114	23	during	during	IN
cord-022561-rv5j1201	114	24	maturation	maturation	NN
cord-022561-rv5j1201	114	25	.	.	.
cord-022561-rv5j1201	115	1	(	(	-LRB-
cord-022561-rv5j1201	115	2	Hemoglobin	hemoglobin	NN
cord-022561-rv5j1201	115	3	stains	stain	VBZ
cord-022561-rv5j1201	115	4	eosinophilic	eosinophilic	JJ
cord-022561-rv5j1201	115	5	,	,	,
cord-022561-rv5j1201	115	6	and	and	CC
cord-022561-rv5j1201	115	7	RNA	RNA	NNP
cord-022561-rv5j1201	115	8	stains	stain	NNS
cord-022561-rv5j1201	115	9	basophilic	basophilic	NNP
cord-022561-rv5j1201	115	10	with	with	IN
cord-022561-rv5j1201	115	11	routine	routine	JJ
cord-022561-rv5j1201	115	12	Romanowsky	Romanowsky	NNP
cord-022561-rv5j1201	115	13	's	's	POS
cord-022561-rv5j1201	115	14	stains	stain	NNS
cord-022561-rv5j1201	115	15	.	.	.
cord-022561-rv5j1201	115	16	)	)	-RRB-
cord-022561-rv5j1201	116	1	As	as	IN
cord-022561-rv5j1201	116	2	granulocytes	granulocyte	NNS
cord-022561-rv5j1201	116	3	(	(	-LRB-
cord-022561-rv5j1201	116	4	e.g.	e.g.	RB
cord-022561-rv5j1201	116	5	,	,	,
cord-022561-rv5j1201	116	6	neutrophils	neutrophil	NNS
cord-022561-rv5j1201	116	7	,	,	,
cord-022561-rv5j1201	116	8	eosinophils	eosinophil	NNS
cord-022561-rv5j1201	116	9	,	,	,
cord-022561-rv5j1201	116	10	and	and	CC
cord-022561-rv5j1201	116	11	basophils	basophil	NNS
cord-022561-rv5j1201	116	12	)	)	-RRB-
cord-022561-rv5j1201	116	13	mature	mature	VBP
cord-022561-rv5j1201	116	14	from	from	IN
cord-022561-rv5j1201	116	15	a	a	DT
cord-022561-rv5j1201	116	16	myeloblast	myeloblast	NN
cord-022561-rv5j1201	116	17	to	to	IN
cord-022561-rv5j1201	116	18	their	-PRON-	PRP$
cord-022561-rv5j1201	116	19	mature	mature	JJ
cord-022561-rv5j1201	116	20	forms	form	NNS
cord-022561-rv5j1201	116	21	,	,	,
cord-022561-rv5j1201	116	22	their	-PRON-	PRP$
cord-022561-rv5j1201	116	23	nuclei	nucleus	NNS
cord-022561-rv5j1201	116	24	become	become	VBP
cord-022561-rv5j1201	116	25	dense	dense	JJ
cord-022561-rv5j1201	116	26	and	and	CC
cord-022561-rv5j1201	116	27	segmented	segmented	JJ
cord-022561-rv5j1201	116	28	.	.	.
cord-022561-rv5j1201	117	1	Granulocytes	granulocyte	NNS
cord-022561-rv5j1201	117	2	acquire	acquire	VBP
cord-022561-rv5j1201	117	3	their	-PRON-	PRP$
cord-022561-rv5j1201	117	4	secondary	secondary	JJ
cord-022561-rv5j1201	117	5	or	or	CC
cord-022561-rv5j1201	117	6	specific	specific	JJ
cord-022561-rv5j1201	117	7	granules	granule	NNS
cord-022561-rv5j1201	117	8	during	during	IN
cord-022561-rv5j1201	117	9	the	the	DT
cord-022561-rv5j1201	117	10	myelocyte	myelocyte	NNP
cord-022561-rv5j1201	117	11	stage	stage	NN
cord-022561-rv5j1201	117	12	and	and	CC
cord-022561-rv5j1201	117	13	can	can	MD
cord-022561-rv5j1201	117	14	be	be	VB
cord-022561-rv5j1201	117	15	morphologically	morphologically	RB
cord-022561-rv5j1201	117	16	differentiated	differentiated	JJ
cord-022561-rv5j1201	117	17	starting	start	VBG
cord-022561-rv5j1201	117	18	at	at	IN
cord-022561-rv5j1201	117	19	this	this	DT
cord-022561-rv5j1201	117	20	stage	stage	NN
cord-022561-rv5j1201	117	21	.	.	.
cord-022561-rv5j1201	118	1	Neutrophils	neutrophil	NNS
cord-022561-rv5j1201	118	2	have	have	VBP
cord-022561-rv5j1201	118	3	neutral	neutral	RB
cord-022561-rv5j1201	118	4	-	-	HYPH
cord-022561-rv5j1201	118	5	staining	stain	VBG
cord-022561-rv5j1201	118	6	secondary	secondary	JJ
cord-022561-rv5j1201	118	7	granules	granule	NNS
cord-022561-rv5j1201	118	8	,	,	,
cord-022561-rv5j1201	118	9	eosinophil	eosinophil	JJ
cord-022561-rv5j1201	118	10	secondary	secondary	JJ
cord-022561-rv5j1201	118	11	granules	granule	NNS
cord-022561-rv5j1201	118	12	have	have	VBP
cord-022561-rv5j1201	118	13	an	an	DT
cord-022561-rv5j1201	118	14	affinity	affinity	NN
cord-022561-rv5j1201	118	15	for	for	IN
cord-022561-rv5j1201	118	16	acidic	acidic	JJ
cord-022561-rv5j1201	118	17	or	or	CC
cord-022561-rv5j1201	118	18	eosin	eosin	JJ
cord-022561-rv5j1201	118	19	dyes	dye	NNS
cord-022561-rv5j1201	118	20	,	,	,
cord-022561-rv5j1201	118	21	and	and	CC
cord-022561-rv5j1201	118	22	basophil	basophil	NNP
cord-022561-rv5j1201	118	23	secondary	secondary	JJ
cord-022561-rv5j1201	118	24	granules	granule	NNS
cord-022561-rv5j1201	118	25	have	have	VBP
cord-022561-rv5j1201	118	26	an	an	DT
cord-022561-rv5j1201	118	27	affinity	affinity	NN
cord-022561-rv5j1201	118	28	for	for	IN
cord-022561-rv5j1201	118	29	basic	basic	JJ
cord-022561-rv5j1201	118	30	dyes	dye	NNS
cord-022561-rv5j1201	118	31	.	.	.
cord-022561-rv5j1201	119	1	Monoblasts	monoblast	NNS
cord-022561-rv5j1201	119	2	differentiate	differentiate	VBP
cord-022561-rv5j1201	119	3	into	into	IN
cord-022561-rv5j1201	119	4	promonocytes	promonocyte	NNS
cord-022561-rv5j1201	119	5	with	with	IN
cord-022561-rv5j1201	119	6	ruffled	ruffled	JJ
cord-022561-rv5j1201	119	7	nuclear	nuclear	JJ
cord-022561-rv5j1201	119	8	boarders	boarder	NNS
cord-022561-rv5j1201	119	9	and	and	CC
cord-022561-rv5j1201	119	10	then	then	RB
cord-022561-rv5j1201	119	11	into	into	IN
cord-022561-rv5j1201	119	12	monocytes	monocyte	NNS
cord-022561-rv5j1201	119	13	.	.	.
cord-022561-rv5j1201	120	1	In	in	IN
cord-022561-rv5j1201	120	2	most	most	JJS
cord-022561-rv5j1201	120	3	mammals	mammal	NNS
cord-022561-rv5j1201	120	4	,	,	,
cord-022561-rv5j1201	120	5	mature	mature	JJ
cord-022561-rv5j1201	120	6	erythrocytes	erythrocyte	NNS
cord-022561-rv5j1201	120	7	have	have	VBP
cord-022561-rv5j1201	120	8	a	a	DT
cord-022561-rv5j1201	120	9	biconcave	biconcave	NN
cord-022561-rv5j1201	120	10	disk	disk	NN
cord-022561-rv5j1201	120	11	shape	shape	NN
cord-022561-rv5j1201	120	12	,	,	,
cord-022561-rv5j1201	120	13	called	call	VBD
cord-022561-rv5j1201	120	14	a	a	DT
cord-022561-rv5j1201	120	15	discocyte	discocyte	NN
cord-022561-rv5j1201	120	16	.	.	.
cord-022561-rv5j1201	121	1	Microscopically	microscopically	RB
cord-022561-rv5j1201	121	2	,	,	,
cord-022561-rv5j1201	121	3	these	these	DT
cord-022561-rv5j1201	121	4	cells	cell	NNS
cord-022561-rv5j1201	121	5	are	be	VBP
cord-022561-rv5j1201	121	6	round	round	JJ
cord-022561-rv5j1201	121	7	and	and	CC
cord-022561-rv5j1201	121	8	eosinophilic	eosinophilic	JJ
cord-022561-rv5j1201	121	9	with	with	IN
cord-022561-rv5j1201	121	10	a	a	DT
cord-022561-rv5j1201	121	11	central	central	JJ
cord-022561-rv5j1201	121	12	area	area	NN
cord-022561-rv5j1201	121	13	of	of	IN
cord-022561-rv5j1201	121	14	pallor	pallor	NN
cord-022561-rv5j1201	121	15	.	.	.
cord-022561-rv5j1201	122	1	However	however	RB
cord-022561-rv5j1201	122	2	,	,	,
cord-022561-rv5j1201	122	3	the	the	DT
cord-022561-rv5j1201	122	4	central	central	JJ
cord-022561-rv5j1201	122	5	concavity	concavity	NN
cord-022561-rv5j1201	122	6	may	may	MD
cord-022561-rv5j1201	122	7	not	not	RB
cord-022561-rv5j1201	122	8	be	be	VB
cord-022561-rv5j1201	122	9	microscopically	microscopically	RB
cord-022561-rv5j1201	122	10	apparent	apparent	JJ
cord-022561-rv5j1201	122	11	in	in	IN
cord-022561-rv5j1201	122	12	species	specie	NNS
cord-022561-rv5j1201	122	13	other	other	JJ
cord-022561-rv5j1201	122	14	than	than	IN
cord-022561-rv5j1201	122	15	the	the	DT
cord-022561-rv5j1201	122	16	dog	dog	NN
cord-022561-rv5j1201	122	17	.	.	.
cord-022561-rv5j1201	123	1	Camelids	Camelids	NNP
cord-022561-rv5j1201	123	2	normally	normally	RB
cord-022561-rv5j1201	123	3	have	have	VBP
cord-022561-rv5j1201	123	4	oval	oval	JJ
cord-022561-rv5j1201	123	5	erythrocytes	erythrocyte	NNS
cord-022561-rv5j1201	123	6	,	,	,
cord-022561-rv5j1201	123	7	termed	term	VBN
cord-022561-rv5j1201	123	8	ovalocytes	ovalocyte	NNS
cord-022561-rv5j1201	123	9	or	or	CC
cord-022561-rv5j1201	123	10	elliptocytes	elliptocyte	NNS
cord-022561-rv5j1201	123	11	,	,	,
cord-022561-rv5j1201	123	12	which	which	WDT
cord-022561-rv5j1201	123	13	facilitate	facilitate	VBP
cord-022561-rv5j1201	123	14	better	well	JJR
cord-022561-rv5j1201	123	15	gas	gas	NN
cord-022561-rv5j1201	123	16	exchange	exchange	NN
cord-022561-rv5j1201	123	17	at	at	IN
cord-022561-rv5j1201	123	18	high	high	JJ
cord-022561-rv5j1201	123	19	altitudes	altitude	NNS
cord-022561-rv5j1201	123	20	.	.	.
cord-022561-rv5j1201	124	1	The	the	DT
cord-022561-rv5j1201	124	2	erythrocytes	erythrocyte	NNS
cord-022561-rv5j1201	124	3	of	of	IN
cord-022561-rv5j1201	124	4	some	some	DT
cord-022561-rv5j1201	124	5	animals	animal	NNS
cord-022561-rv5j1201	124	6	are	be	VBP
cord-022561-rv5j1201	124	7	prone	prone	JJ
cord-022561-rv5j1201	124	8	to	to	IN
cord-022561-rv5j1201	124	9	in	in	FW
cord-022561-rv5j1201	124	10	vitro	vitro	FW
cord-022561-rv5j1201	124	11	shape	shape	NN
cord-022561-rv5j1201	124	12	change	change	NN
cord-022561-rv5j1201	124	13	,	,	,
cord-022561-rv5j1201	124	14	including	include	VBG
cord-022561-rv5j1201	124	15	those	those	DT
cord-022561-rv5j1201	124	16	of	of	IN
cord-022561-rv5j1201	124	17	cervids	cervid	NNS
cord-022561-rv5j1201	124	18	,	,	,
cord-022561-rv5j1201	124	19	pigs	pig	NNS
cord-022561-rv5j1201	124	20	,	,	,
cord-022561-rv5j1201	124	21	and	and	CC
cord-022561-rv5j1201	124	22	some	some	DT
cord-022561-rv5j1201	124	23	goat	goat	NN
cord-022561-rv5j1201	124	24	breeds	breed	NNS
cord-022561-rv5j1201	124	25	(	(	-LRB-
cord-022561-rv5j1201	124	26	e.g.	e.g.	RB
cord-022561-rv5j1201	124	27	,	,	,
cord-022561-rv5j1201	124	28	Angora	Angora	NNP
cord-022561-rv5j1201	124	29	)	)	-RRB-
cord-022561-rv5j1201	124	30	.	.	.
cord-022561-rv5j1201	125	1	Erythrocyte	Erythrocyte	NNP
cord-022561-rv5j1201	125	2	size	size	NN
cord-022561-rv5j1201	125	3	during	during	IN
cord-022561-rv5j1201	125	4	health	health	NN
cord-022561-rv5j1201	125	5	depends	depend	VBZ
cord-022561-rv5j1201	125	6	on	on	IN
cord-022561-rv5j1201	125	7	the	the	DT
cord-022561-rv5j1201	125	8	species	specie	NNS
cord-022561-rv5j1201	125	9	,	,	,
cord-022561-rv5j1201	125	10	breed	breed	NN
cord-022561-rv5j1201	125	11	,	,	,
cord-022561-rv5j1201	125	12	and	and	CC
cord-022561-rv5j1201	125	13	age	age	NN
cord-022561-rv5j1201	125	14	of	of	IN
cord-022561-rv5j1201	125	15	the	the	DT
cord-022561-rv5j1201	125	16	animal	animal	NN
cord-022561-rv5j1201	125	17	.	.	.
cord-022561-rv5j1201	126	1	In	in	IN
cord-022561-rv5j1201	126	2	dogs	dog	NNS
cord-022561-rv5j1201	126	3	,	,	,
cord-022561-rv5j1201	126	4	some	some	DT
cord-022561-rv5j1201	126	5	breeds	breed	NNS
cord-022561-rv5j1201	126	6	have	have	VBP
cord-022561-rv5j1201	126	7	relatively	relatively	RB
cord-022561-rv5j1201	126	8	smaller	small	JJR
cord-022561-rv5j1201	126	9	(	(	-LRB-
cord-022561-rv5j1201	126	10	e.g.	e.g.	RB
cord-022561-rv5j1201	126	11	,	,	,
cord-022561-rv5j1201	126	12	Akitas	Akitas	NNPS
cord-022561-rv5j1201	126	13	and	and	CC
cord-022561-rv5j1201	126	14	Shibas	Shibas	NNPS
cord-022561-rv5j1201	126	15	)	)	-RRB-
cord-022561-rv5j1201	126	16	or	or	CC
cord-022561-rv5j1201	126	17	larger	large	JJR
cord-022561-rv5j1201	126	18	(	(	-LRB-
cord-022561-rv5j1201	126	19	e.g.	e.g.	RB
cord-022561-rv5j1201	126	20	,	,	,
cord-022561-rv5j1201	126	21	some	some	DT
cord-022561-rv5j1201	126	22	poodles	poodle	NNS
cord-022561-rv5j1201	126	23	)	)	-RRB-
cord-022561-rv5j1201	126	24	erythrocytes	erythrocyte	NNS
cord-022561-rv5j1201	126	25	.	.	.
cord-022561-rv5j1201	127	1	Akitas	Akitas	NNPS
cord-022561-rv5j1201	127	2	and	and	CC
cord-022561-rv5j1201	127	3	Shibas	Shibas	NNPS
cord-022561-rv5j1201	127	4	also	also	RB
cord-022561-rv5j1201	127	5	have	have	VBP
cord-022561-rv5j1201	127	6	a	a	DT
cord-022561-rv5j1201	127	7	high	high	JJ
cord-022561-rv5j1201	127	8	concentration	concentration	NN
cord-022561-rv5j1201	127	9	of	of	IN
cord-022561-rv5j1201	127	10	potassium	potassium	NN
cord-022561-rv5j1201	127	11	,	,	,
cord-022561-rv5j1201	127	12	unlike	unlike	IN
cord-022561-rv5j1201	127	13	erythrocytes	erythrocyte	NNS
cord-022561-rv5j1201	127	14	in	in	IN
cord-022561-rv5j1201	127	15	other	other	JJ
cord-022561-rv5j1201	127	16	dogs	dog	NNS
cord-022561-rv5j1201	127	17	.	.	.
cord-022561-rv5j1201	128	1	Juvenile	juvenile	JJ
cord-022561-rv5j1201	128	2	animals	animal	NNS
cord-022561-rv5j1201	128	3	may	may	MD
cord-022561-rv5j1201	128	4	have	have	VB
cord-022561-rv5j1201	128	5	larger	large	JJR
cord-022561-rv5j1201	128	6	erythrocytes	erythrocyte	NNS
cord-022561-rv5j1201	128	7	because	because	IN
cord-022561-rv5j1201	128	8	of	of	IN
cord-022561-rv5j1201	128	9	the	the	DT
cord-022561-rv5j1201	128	10	persistence	persistence	NN
cord-022561-rv5j1201	128	11	of	of	IN
cord-022561-rv5j1201	128	12	fetal	fetal	JJ
cord-022561-rv5j1201	128	13	erythrocytes	erythrocyte	NNS
cord-022561-rv5j1201	128	14	,	,	,
cord-022561-rv5j1201	128	15	which	which	WDT
cord-022561-rv5j1201	128	16	is	be	VBZ
cord-022561-rv5j1201	128	17	followed	follow	VBN
cord-022561-rv5j1201	128	18	by	by	IN
cord-022561-rv5j1201	128	19	a	a	DT
cord-022561-rv5j1201	128	20	period	period	NN
cord-022561-rv5j1201	128	21	of	of	IN
cord-022561-rv5j1201	128	22	relatively	relatively	RB
cord-022561-rv5j1201	128	23	smaller	small	JJR
cord-022561-rv5j1201	128	24	cells	cell	NNS
cord-022561-rv5j1201	128	25	before	before	IN
cord-022561-rv5j1201	128	26	reaching	reach	VBG
cord-022561-rv5j1201	128	27	adult	adult	NN
cord-022561-rv5j1201	128	28	reference	reference	NN
cord-022561-rv5j1201	128	29	intervals	interval	NNS
cord-022561-rv5j1201	128	30	.	.	.
cord-022561-rv5j1201	129	1	Mature	mature	JJ
cord-022561-rv5j1201	129	2	mammalian	mammalian	JJ
cord-022561-rv5j1201	129	3	erythrocytes	erythrocyte	NNS
cord-022561-rv5j1201	129	4	lack	lack	VBP
cord-022561-rv5j1201	129	5	nuclei	nucleus	NNS
cord-022561-rv5j1201	129	6	and	and	CC
cord-022561-rv5j1201	129	7	organelles	organelle	NNS
cord-022561-rv5j1201	129	8	and	and	CC
cord-022561-rv5j1201	129	9	are	be	VBP
cord-022561-rv5j1201	129	10	thus	thus	RB
cord-022561-rv5j1201	129	11	incapable	incapable	JJ
cord-022561-rv5j1201	129	12	of	of	IN
cord-022561-rv5j1201	129	13	transcription	transcription	NN
cord-022561-rv5j1201	129	14	,	,	,
cord-022561-rv5j1201	129	15	translation	translation	NN
cord-022561-rv5j1201	129	16	,	,	,
cord-022561-rv5j1201	129	17	and	and	CC
cord-022561-rv5j1201	129	18	oxidative	oxidative	JJ
cord-022561-rv5j1201	129	19	metabolism	metabolism	NN
cord-022561-rv5j1201	129	20	.	.	.
cord-022561-rv5j1201	130	1	However	however	RB
cord-022561-rv5j1201	130	2	,	,	,
cord-022561-rv5j1201	130	3	they	-PRON-	PRP
cord-022561-rv5j1201	130	4	do	do	VBP
cord-022561-rv5j1201	130	5	require	require	VB
cord-022561-rv5j1201	130	6	energy	energy	NN
cord-022561-rv5j1201	130	7	for	for	IN
cord-022561-rv5j1201	130	8	various	various	JJ
cord-022561-rv5j1201	130	9	functions	function	NNS
cord-022561-rv5j1201	130	10	,	,	,
cord-022561-rv5j1201	130	11	including	include	VBG
cord-022561-rv5j1201	130	12	maintenance	maintenance	NN
cord-022561-rv5j1201	130	13	of	of	IN
cord-022561-rv5j1201	130	14	shape	shape	NN
cord-022561-rv5j1201	130	15	and	and	CC
cord-022561-rv5j1201	130	16	deformability	deformability	NN
cord-022561-rv5j1201	130	17	,	,	,
cord-022561-rv5j1201	130	18	active	active	JJ
cord-022561-rv5j1201	130	19	transport	transport	NN
cord-022561-rv5j1201	130	20	,	,	,
cord-022561-rv5j1201	130	21	and	and	CC
cord-022561-rv5j1201	130	22	prevention	prevention	NN
cord-022561-rv5j1201	130	23	of	of	IN
cord-022561-rv5j1201	130	24	oxidative	oxidative	JJ
cord-022561-rv5j1201	130	25	damage	damage	NN
cord-022561-rv5j1201	130	26	.	.	.
cord-022561-rv5j1201	131	1	Red	red	JJ
cord-022561-rv5j1201	131	2	blood	blood	NN
cord-022561-rv5j1201	131	3	cells	cell	NNS
cord-022561-rv5j1201	131	4	generate	generate	VBP
cord-022561-rv5j1201	131	5	this	this	DT
cord-022561-rv5j1201	131	6	energy	energy	NN
cord-022561-rv5j1201	131	7	entirely	entirely	RB
cord-022561-rv5j1201	131	8	through	through	IN
cord-022561-rv5j1201	131	9	glycolysis	glycolysis	NN
cord-022561-rv5j1201	131	10	(	(	-LRB-
cord-022561-rv5j1201	131	11	also	also	RB
cord-022561-rv5j1201	131	12	known	know	VBN
cord-022561-rv5j1201	131	13	as	as	IN
cord-022561-rv5j1201	131	14	the	the	DT
cord-022561-rv5j1201	131	15	Embden	Embden	NNP
cord-022561-rv5j1201	131	16	-	-	HYPH
cord-022561-rv5j1201	131	17	Meyerhof	Meyerhof	NNP
cord-022561-rv5j1201	131	18	pathway	pathway	NN
cord-022561-rv5j1201	131	19	)	)	-RRB-
cord-022561-rv5j1201	131	20	.	.	.
cord-022561-rv5j1201	132	1	Except	except	IN
cord-022561-rv5j1201	132	2	in	in	IN
cord-022561-rv5j1201	132	3	pigs	pig	NNS
cord-022561-rv5j1201	132	4	,	,	,
cord-022561-rv5j1201	132	5	glucose	glucose	NN
cord-022561-rv5j1201	132	6	enters	enter	VBZ
cord-022561-rv5j1201	132	7	erythrocytes	erythrocyte	NNS
cord-022561-rv5j1201	132	8	from	from	IN
cord-022561-rv5j1201	132	9	the	the	DT
cord-022561-rv5j1201	132	10	plasma	plasma	NN
cord-022561-rv5j1201	132	11	through	through	IN
cord-022561-rv5j1201	132	12	an	an	DT
cord-022561-rv5j1201	132	13	insulin	insulin	NN
cord-022561-rv5j1201	132	14	-	-	HYPH
cord-022561-rv5j1201	132	15	independent	independent	JJ
cord-022561-rv5j1201	132	16	,	,	,
cord-022561-rv5j1201	132	17	integral	integral	JJ
cord-022561-rv5j1201	132	18	membrane	membrane	NN
cord-022561-rv5j1201	132	19	glucose	glucose	NN
cord-022561-rv5j1201	132	20	transporter	transporter	NN
cord-022561-rv5j1201	132	21	.	.	.
cord-022561-rv5j1201	133	1	Within	within	IN
cord-022561-rv5j1201	133	2	circulation	circulation	NN
cord-022561-rv5j1201	133	3	the	the	DT
cord-022561-rv5j1201	133	4	erythrocyte	erythrocyte	NN
cord-022561-rv5j1201	133	5	mean	mean	VBP
cord-022561-rv5j1201	133	6	life	life	NN
cord-022561-rv5j1201	133	7	span	span	NN
cord-022561-rv5j1201	133	8	varies	vary	VBZ
cord-022561-rv5j1201	133	9	between	between	IN
cord-022561-rv5j1201	133	10	species	specie	NNS
cord-022561-rv5j1201	133	11	and	and	CC
cord-022561-rv5j1201	133	12	is	be	VBZ
cord-022561-rv5j1201	133	13	related	relate	VBN
cord-022561-rv5j1201	133	14	to	to	IN
cord-022561-rv5j1201	133	15	body	body	NN
cord-022561-rv5j1201	133	16	weight	weight	NN
cord-022561-rv5j1201	133	17	and	and	CC
cord-022561-rv5j1201	133	18	metabolic	metabolic	JJ
cord-022561-rv5j1201	133	19	rate	rate	NN
cord-022561-rv5j1201	133	20	:	:	:
cord-022561-rv5j1201	133	21	approximately	approximately	RB
cord-022561-rv5j1201	133	22	150	150	CD
cord-022561-rv5j1201	133	23	days	day	NNS
cord-022561-rv5j1201	133	24	in	in	IN
cord-022561-rv5j1201	133	25	horses	horse	NNS
cord-022561-rv5j1201	133	26	and	and	CC
cord-022561-rv5j1201	133	27	cattle	cattle	NNS
cord-022561-rv5j1201	133	28	,	,	,
cord-022561-rv5j1201	133	29	100	100	CD
cord-022561-rv5j1201	133	30	days	day	NNS
cord-022561-rv5j1201	133	31	in	in	IN
cord-022561-rv5j1201	133	32	dogs	dog	NNS
cord-022561-rv5j1201	133	33	,	,	,
cord-022561-rv5j1201	133	34	and	and	CC
cord-022561-rv5j1201	133	35	70	70	CD
cord-022561-rv5j1201	133	36	days	day	NNS
cord-022561-rv5j1201	133	37	in	in	IN
cord-022561-rv5j1201	133	38	cats	cat	NNS
cord-022561-rv5j1201	133	39	.	.	.
cord-022561-rv5j1201	134	1	When	when	WRB
cord-022561-rv5j1201	134	2	erythrocytes	erythrocyte	NNS
cord-022561-rv5j1201	134	3	reach	reach	VBP
cord-022561-rv5j1201	134	4	the	the	DT
cord-022561-rv5j1201	134	5	end	end	NN
cord-022561-rv5j1201	134	6	of	of	IN
cord-022561-rv5j1201	134	7	their	-PRON-	PRP$
cord-022561-rv5j1201	134	8	life	life	NN
cord-022561-rv5j1201	134	9	span	span	NN
cord-022561-rv5j1201	134	10	,	,	,
cord-022561-rv5j1201	134	11	they	-PRON-	PRP
cord-022561-rv5j1201	134	12	are	be	VBP
cord-022561-rv5j1201	134	13	destroyed	destroy	VBN
cord-022561-rv5j1201	134	14	in	in	IN
cord-022561-rv5j1201	134	15	a	a	DT
cord-022561-rv5j1201	134	16	process	process	NN
cord-022561-rv5j1201	134	17	termed	term	VBN
cord-022561-rv5j1201	134	18	hemolysis	hemolysis	NN
cord-022561-rv5j1201	134	19	.	.	.
cord-022561-rv5j1201	135	1	Hemolysis	Hemolysis	NNP
cord-022561-rv5j1201	135	2	may	may	MD
cord-022561-rv5j1201	135	3	occur	occur	VB
cord-022561-rv5j1201	135	4	within	within	IN
cord-022561-rv5j1201	135	5	blood	blood	NN
cord-022561-rv5j1201	135	6	vessels	vessel	NNS
cord-022561-rv5j1201	135	7	(	(	-LRB-
cord-022561-rv5j1201	135	8	intravascular	intravascular	JJ
cord-022561-rv5j1201	135	9	hemolysis	hemolysis	NN
cord-022561-rv5j1201	135	10	)	)	-RRB-
cord-022561-rv5j1201	135	11	or	or	CC
cord-022561-rv5j1201	135	12	by	by	IN
cord-022561-rv5j1201	135	13	sinusoidal	sinusoidal	JJ
cord-022561-rv5j1201	135	14	macrophages	macrophage	NNS
cord-022561-rv5j1201	135	15	(	(	-LRB-
cord-022561-rv5j1201	135	16	extravascular	extravascular	JJ
cord-022561-rv5j1201	135	17	hemolysis	hemolysis	NN
cord-022561-rv5j1201	135	18	)	)	-RRB-
cord-022561-rv5j1201	135	19	.	.	.
cord-022561-rv5j1201	136	1	During	during	IN
cord-022561-rv5j1201	136	2	intravascular	intravascular	JJ
cord-022561-rv5j1201	136	3	hemolysis	hemolysis	NN
cord-022561-rv5j1201	136	4	,	,	,
cord-022561-rv5j1201	136	5	erythrocytes	erythrocyte	NNS
cord-022561-rv5j1201	136	6	release	release	VBP
cord-022561-rv5j1201	136	7	their	-PRON-	PRP$
cord-022561-rv5j1201	136	8	contents	content	NNS
cord-022561-rv5j1201	136	9	,	,	,
cord-022561-rv5j1201	136	10	mostly	mostly	RB
cord-022561-rv5j1201	136	11	hemoglobin	hemoglobin	NN
cord-022561-rv5j1201	136	12	,	,	,
cord-022561-rv5j1201	136	13	directly	directly	RB
cord-022561-rv5j1201	136	14	into	into	IN
cord-022561-rv5j1201	136	15	blood	blood	NN
cord-022561-rv5j1201	136	16	.	.	.
cord-022561-rv5j1201	137	1	However	however	RB
cord-022561-rv5j1201	137	2	,	,	,
cord-022561-rv5j1201	137	3	during	during	IN
cord-022561-rv5j1201	137	4	extravascular	extravascular	JJ
cord-022561-rv5j1201	137	5	hemolysis	hemolysis	NN
cord-022561-rv5j1201	137	6	,	,	,
cord-022561-rv5j1201	137	7	macrophages	macrophage	NNS
cord-022561-rv5j1201	137	8	phagocytize	phagocytize	NNP
cord-022561-rv5j1201	137	9	entire	entire	JJ
cord-022561-rv5j1201	137	10	erythrocytes	erythrocyte	NNS
cord-022561-rv5j1201	137	11	,	,	,
cord-022561-rv5j1201	137	12	leaving	leave	VBG
cord-022561-rv5j1201	137	13	little	little	JJ
cord-022561-rv5j1201	137	14	or	or	CC
cord-022561-rv5j1201	137	15	no	no	DT
cord-022561-rv5j1201	137	16	hemoglobin	hemoglobin	NN
cord-022561-rv5j1201	137	17	in	in	IN
cord-022561-rv5j1201	137	18	the	the	DT
cord-022561-rv5j1201	137	19	blood	blood	NN
cord-022561-rv5j1201	137	20	.	.	.
cord-022561-rv5j1201	138	1	Normal	normal	JJ
cord-022561-rv5j1201	138	2	turnover	turnover	NN
cord-022561-rv5j1201	138	3	of	of	IN
cord-022561-rv5j1201	138	4	erythrocytes	erythrocyte	NNS
cord-022561-rv5j1201	138	5	occurs	occur	VBZ
cord-022561-rv5j1201	138	6	mainly	mainly	RB
cord-022561-rv5j1201	138	7	by	by	IN
cord-022561-rv5j1201	138	8	extravascular	extravascular	JJ
cord-022561-rv5j1201	138	9	hemolysis	hemolysis	NN
cord-022561-rv5j1201	138	10	within	within	IN
cord-022561-rv5j1201	138	11	the	the	DT
cord-022561-rv5j1201	138	12	spleen	spleen	NN
cord-022561-rv5j1201	138	13	,	,	,
cord-022561-rv5j1201	138	14	and	and	CC
cord-022561-rv5j1201	138	15	to	to	IN
cord-022561-rv5j1201	138	16	a	a	DT
cord-022561-rv5j1201	138	17	lesser	less	JJR
cord-022561-rv5j1201	138	18	extent	extent	NN
cord-022561-rv5j1201	138	19	in	in	IN
cord-022561-rv5j1201	138	20	other	other	JJ
cord-022561-rv5j1201	138	21	organs	organ	NNS
cord-022561-rv5j1201	138	22	such	such	JJ
cord-022561-rv5j1201	138	23	as	as	IN
cord-022561-rv5j1201	138	24	the	the	DT
cord-022561-rv5j1201	138	25	liver	liver	NN
cord-022561-rv5j1201	138	26	and	and	CC
cord-022561-rv5j1201	138	27	bone	bone	NN
cord-022561-rv5j1201	138	28	marrow	marrow	NN
cord-022561-rv5j1201	138	29	.	.	.
cord-022561-rv5j1201	139	1	The	the	DT
cord-022561-rv5j1201	139	2	exact	exact	JJ
cord-022561-rv5j1201	139	3	controls	control	NNS
cord-022561-rv5j1201	139	4	are	be	VBP
cord-022561-rv5j1201	139	5	not	not	RB
cord-022561-rv5j1201	139	6	clear	clear	JJ
cord-022561-rv5j1201	139	7	,	,	,
cord-022561-rv5j1201	139	8	but	but	CC
cord-022561-rv5j1201	139	9	factors	factor	NNS
cord-022561-rv5j1201	139	10	that	that	WDT
cord-022561-rv5j1201	139	11	likely	likely	RB
cord-022561-rv5j1201	139	12	play	play	VBP
cord-022561-rv5j1201	139	13	a	a	DT
cord-022561-rv5j1201	139	14	role	role	NN
cord-022561-rv5j1201	139	15	in	in	IN
cord-022561-rv5j1201	139	16	physiologic	physiologic	JJ
cord-022561-rv5j1201	139	17	hemolysis	hemolysis	NN
cord-022561-rv5j1201	139	18	include	include	VBP
cord-022561-rv5j1201	139	19	the	the	DT
cord-022561-rv5j1201	139	20	following	follow	VBG
cord-022561-rv5j1201	139	21	:	:	:
cord-022561-rv5j1201	139	22	•	•	XX
cord-022561-rv5j1201	140	1	Exposure	exposure	NN
cord-022561-rv5j1201	140	2	of	of	IN
cord-022561-rv5j1201	140	3	membrane	membrane	NN
cord-022561-rv5j1201	140	4	components	component	NNS
cord-022561-rv5j1201	140	5	normally	normally	RB
cord-022561-rv5j1201	140	6	sequestered	sequester	VBN
cord-022561-rv5j1201	140	7	on	on	IN
cord-022561-rv5j1201	140	8	the	the	DT
cord-022561-rv5j1201	140	9	inner	inner	JJ
cord-022561-rv5j1201	140	10	leaflet	leaflet	NN
cord-022561-rv5j1201	140	11	of	of	IN
cord-022561-rv5j1201	140	12	the	the	DT
cord-022561-rv5j1201	140	13	erythrocyte	erythrocyte	NN
cord-022561-rv5j1201	140	14	membrane	membrane	NN
cord-022561-rv5j1201	140	15	,	,	,
cord-022561-rv5j1201	140	16	particularly	particularly	RB
cord-022561-rv5j1201	140	17	phosphatidylserine	phosphatidylserine	NN
cord-022561-rv5j1201	140	18	.	.	.
cord-022561-rv5j1201	141	1	reticulocytes	reticulocytes	NNP
cord-022561-rv5j1201	141	2	,	,	,
cord-022561-rv5j1201	141	3	and	and	CC
cord-022561-rv5j1201	141	4	subsequently	subsequently	RB
cord-022561-rv5j1201	141	5	mature	mature	VB
cord-022561-rv5j1201	141	6	erythrocytes	erythrocyte	NNS
cord-022561-rv5j1201	141	7	.	.	.
cord-022561-rv5j1201	142	1	The	the	DT
cord-022561-rv5j1201	142	2	normal	normal	JJ
cord-022561-rv5j1201	142	3	transit	transit	NN
cord-022561-rv5j1201	142	4	time	time	NN
cord-022561-rv5j1201	142	5	from	from	IN
cord-022561-rv5j1201	142	6	rubriblast	rubriblast	NN
cord-022561-rv5j1201	142	7	to	to	IN
cord-022561-rv5j1201	142	8	mature	mature	JJ
cord-022561-rv5j1201	142	9	erythrocyte	erythrocyte	NN
cord-022561-rv5j1201	142	10	is	be	VBZ
cord-022561-rv5j1201	142	11	approximately	approximately	RB
cord-022561-rv5j1201	142	12	1	1	CD
cord-022561-rv5j1201	142	13	week	week	NN
cord-022561-rv5j1201	142	14	.	.	.
cord-022561-rv5j1201	143	1	Reticulocytes	reticulocyte	NNS
cord-022561-rv5j1201	143	2	start	start	VBP
cord-022561-rv5j1201	143	3	maturing	mature	VBG
cord-022561-rv5j1201	143	4	in	in	IN
cord-022561-rv5j1201	143	5	the	the	DT
cord-022561-rv5j1201	143	6	bone	bone	NN
cord-022561-rv5j1201	143	7	marrow	marrow	NN
cord-022561-rv5j1201	143	8	but	but	CC
cord-022561-rv5j1201	143	9	finish	finish	VBP
cord-022561-rv5j1201	143	10	their	-PRON-	PRP$
cord-022561-rv5j1201	143	11	maturation	maturation	NN
cord-022561-rv5j1201	143	12	in	in	IN
cord-022561-rv5j1201	143	13	the	the	DT
cord-022561-rv5j1201	143	14	blood	blood	NN
cord-022561-rv5j1201	143	15	circulation	circulation	NN
cord-022561-rv5j1201	143	16	and	and	CC
cord-022561-rv5j1201	143	17	spleen	spleen	NNS
cord-022561-rv5j1201	143	18	.	.	.
cord-022561-rv5j1201	144	1	Horses	horse	NNS
cord-022561-rv5j1201	144	2	are	be	VBP
cord-022561-rv5j1201	144	3	an	an	DT
cord-022561-rv5j1201	144	4	exception	exception	NN
cord-022561-rv5j1201	144	5	in	in	IN
cord-022561-rv5j1201	144	6	that	that	IN
cord-022561-rv5j1201	144	7	they	-PRON-	PRP
cord-022561-rv5j1201	144	8	do	do	VBP
cord-022561-rv5j1201	144	9	not	not	RB
cord-022561-rv5j1201	144	10	release	release	VB
cord-022561-rv5j1201	144	11	reticulocytes	reticulocyte	NNS
cord-022561-rv5j1201	144	12	into	into	IN
cord-022561-rv5j1201	144	13	circulation	circulation	NN
cord-022561-rv5j1201	144	14	,	,	,
cord-022561-rv5j1201	144	15	even	even	RB
cord-022561-rv5j1201	144	16	in	in	IN
cord-022561-rv5j1201	144	17	situations	situation	NNS
cord-022561-rv5j1201	144	18	of	of	IN
cord-022561-rv5j1201	144	19	increased	increase	VBN
cord-022561-rv5j1201	144	20	demand	demand	NN
cord-022561-rv5j1201	144	21	.	.	.
cord-022561-rv5j1201	145	1	Unlike	unlike	IN
cord-022561-rv5j1201	145	2	mature	mature	JJ
cord-022561-rv5j1201	145	3	erythrocytes	erythrocyte	NNS
cord-022561-rv5j1201	145	4	,	,	,
cord-022561-rv5j1201	145	5	which	which	WDT
cord-022561-rv5j1201	145	6	lack	lack	VBP
cord-022561-rv5j1201	145	7	organelles	organelle	NNS
cord-022561-rv5j1201	145	8	,	,	,
cord-022561-rv5j1201	145	9	reticulocytes	reticulocyte	NNS
cord-022561-rv5j1201	145	10	still	still	RB
cord-022561-rv5j1201	145	11	contain	contain	VBP
cord-022561-rv5j1201	145	12	ribosomes	ribosome	NNS
cord-022561-rv5j1201	145	13	and	and	CC
cord-022561-rv5j1201	145	14	mitochondria	mitochondrion	NNS
cord-022561-rv5j1201	145	15	,	,	,
cord-022561-rv5j1201	145	16	mainly	mainly	RB
cord-022561-rv5j1201	145	17	to	to	TO
cord-022561-rv5j1201	145	18	support	support	VB
cord-022561-rv5j1201	145	19	completion	completion	NN
cord-022561-rv5j1201	145	20	of	of	IN
cord-022561-rv5j1201	145	21	hemoglobin	hemoglobin	NN
cord-022561-rv5j1201	145	22	synthesis	synthesis	NN
cord-022561-rv5j1201	145	23	.	.	.
cord-022561-rv5j1201	146	1	These	these	DT
cord-022561-rv5j1201	146	2	remaining	remain	VBG
cord-022561-rv5j1201	146	3	organelles	organelle	NNS
cord-022561-rv5j1201	146	4	impart	impart	VBP
cord-022561-rv5j1201	146	5	a	a	DT
cord-022561-rv5j1201	146	6	bluish	bluish	JJ
cord-022561-rv5j1201	146	7	-	-	HYPH
cord-022561-rv5j1201	146	8	purple	purple	JJ
cord-022561-rv5j1201	146	9	cast	cast	NN
cord-022561-rv5j1201	146	10	(	(	-LRB-
cord-022561-rv5j1201	146	11	polychromasia	polychromasia	NNP
cord-022561-rv5j1201	146	12	)	)	-RRB-
cord-022561-rv5j1201	146	13	to	to	IN
cord-022561-rv5j1201	146	14	reticulocytes	reticulocyte	NNS
cord-022561-rv5j1201	146	15	on	on	IN
cord-022561-rv5j1201	146	16	routine	routine	JJ
cord-022561-rv5j1201	146	17	blood	blood	NN
cord-022561-rv5j1201	146	18	smear	smear	NN
cord-022561-rv5j1201	146	19	examination	examination	NN
cord-022561-rv5j1201	146	20	.	.	.
cord-022561-rv5j1201	147	1	The	the	DT
cord-022561-rv5j1201	147	2	resultant	resultant	JJ
cord-022561-rv5j1201	147	3	cells	cell	NNS
cord-022561-rv5j1201	147	4	are	be	VBP
cord-022561-rv5j1201	147	5	termed	term	VBN
cord-022561-rv5j1201	147	6	polychromatophils	polychromatophil	NNS
cord-022561-rv5j1201	147	7	.	.	.
cord-022561-rv5j1201	148	1	Because	because	IN
cord-022561-rv5j1201	148	2	older	old	JJR
cord-022561-rv5j1201	148	3	reticulocytes	reticulocyte	NNS
cord-022561-rv5j1201	148	4	do	do	VBP
cord-022561-rv5j1201	148	5	not	not	RB
cord-022561-rv5j1201	148	6	exhibit	exhibit	VB
cord-022561-rv5j1201	148	7	polychromasia	polychromasia	NNS
cord-022561-rv5j1201	148	8	,	,	,
cord-022561-rv5j1201	148	9	more	more	RBR
cord-022561-rv5j1201	148	10	sensitive	sensitive	JJ
cord-022561-rv5j1201	148	11	laboratory	laboratory	NN
cord-022561-rv5j1201	148	12	techniques	technique	NNS
cord-022561-rv5j1201	148	13	must	must	MD
cord-022561-rv5j1201	148	14	be	be	VB
cord-022561-rv5j1201	148	15	used	use	VBN
cord-022561-rv5j1201	148	16	for	for	IN
cord-022561-rv5j1201	148	17	accurate	accurate	JJ
cord-022561-rv5j1201	148	18	reticulocyte	reticulocyte	JJ
cord-022561-rv5j1201	148	19	quantification	quantification	NN
cord-022561-rv5j1201	148	20	.	.	.
cord-022561-rv5j1201	149	1	When	when	WRB
cord-022561-rv5j1201	149	2	a	a	DT
cord-022561-rv5j1201	149	3	blood	blood	NN
cord-022561-rv5j1201	149	4	sample	sample	NN
cord-022561-rv5j1201	149	5	is	be	VBZ
cord-022561-rv5j1201	149	6	incubated	incubate	VBN
cord-022561-rv5j1201	149	7	with	with	IN
cord-022561-rv5j1201	149	8	new	new	JJ
cord-022561-rv5j1201	149	9	methylene	methylene	NN
cord-022561-rv5j1201	149	10	blue	blue	JJ
cord-022561-rv5j1201	149	11	stain	stain	NN
cord-022561-rv5j1201	149	12	,	,	,
cord-022561-rv5j1201	149	13	the	the	DT
cord-022561-rv5j1201	149	14	reticulocytes	reticulocyte	NNS
cord-022561-rv5j1201	149	15	'	'	POS
cord-022561-rv5j1201	149	16	ribosomal	ribosomal	JJ
cord-022561-rv5j1201	149	17	RNA	RNA	NNP
cord-022561-rv5j1201	149	18	precipitates	precipitate	VBZ
cord-022561-rv5j1201	149	19	to	to	TO
cord-022561-rv5j1201	149	20	form	form	VB
cord-022561-rv5j1201	149	21	irregular	irregular	JJ
cord-022561-rv5j1201	149	22	,	,	,
cord-022561-rv5j1201	149	23	dark	dark	JJ
cord-022561-rv5j1201	149	24	aggregates	aggregate	NNS
cord-022561-rv5j1201	149	25	.	.	.
cord-022561-rv5j1201	150	1	Cats	cat	NNS
cord-022561-rv5j1201	150	2	also	also	RB
cord-022561-rv5j1201	150	3	have	have	VBP
cord-022561-rv5j1201	150	4	a	a	DT
cord-022561-rv5j1201	150	5	more	more	RBR
cord-022561-rv5j1201	150	6	mature	mature	JJ
cord-022561-rv5j1201	150	7	form	form	NN
cord-022561-rv5j1201	150	8	of	of	IN
cord-022561-rv5j1201	150	9	reticulocyte	reticulocyte	NNP
cord-022561-rv5j1201	150	10	,	,	,
cord-022561-rv5j1201	150	11	termed	term	VBD
cord-022561-rv5j1201	150	12	punctate	punctate	NNP
cord-022561-rv5j1201	150	13	reticulocyte	reticulocyte	NNP
cord-022561-rv5j1201	150	14	,	,	,
cord-022561-rv5j1201	150	15	which	which	WDT
cord-022561-rv5j1201	150	16	is	be	VBZ
cord-022561-rv5j1201	150	17	stippled	stipple	VBN
cord-022561-rv5j1201	150	18	when	when	WRB
cord-022561-rv5j1201	150	19	stained	stain	VBN
cord-022561-rv5j1201	150	20	with	with	IN
cord-022561-rv5j1201	150	21	new	new	JJ
cord-022561-rv5j1201	150	22	methylene	methylene	NN
cord-022561-rv5j1201	150	23	blue	blue	NN
cord-022561-rv5j1201	150	24	.	.	.
cord-022561-rv5j1201	151	1	Punctate	Punctate	NNP
cord-022561-rv5j1201	151	2	reticulocytes	reticulocyte	NNS
cord-022561-rv5j1201	151	3	indicate	indicate	VBP
cord-022561-rv5j1201	151	4	prior	prior	RB
cord-022561-rv5j1201	151	5	,	,	,
cord-022561-rv5j1201	151	6	not	not	RB
cord-022561-rv5j1201	151	7	active	active	JJ
cord-022561-rv5j1201	151	8	,	,	,
cord-022561-rv5j1201	151	9	regeneration	regeneration	NN
cord-022561-rv5j1201	151	10	and	and	CC
cord-022561-rv5j1201	151	11	do	do	VBP
cord-022561-rv5j1201	151	12	not	not	RB
cord-022561-rv5j1201	151	13	appear	appear	VB
cord-022561-rv5j1201	151	14	polychromatophilic	polychromatophilic	JJ
cord-022561-rv5j1201	151	15	on	on	IN
cord-022561-rv5j1201	151	16	routine	routine	JJ
cord-022561-rv5j1201	151	17	blood	blood	NN
cord-022561-rv5j1201	151	18	smear	smear	NN
cord-022561-rv5j1201	151	19	evaluation	evaluation	NN
cord-022561-rv5j1201	151	20	.	.	.
cord-022561-rv5j1201	151	21	 	 	_SP
cord-022561-rv5j1201	152	1	storage	storage	NN
cord-022561-rv5j1201	152	2	pool	pool	NN
cord-022561-rv5j1201	152	3	,	,	,
cord-022561-rv5j1201	152	4	which	which	WDT
cord-022561-rv5j1201	152	5	consists	consist	VBZ
cord-022561-rv5j1201	152	6	of	of	IN
cord-022561-rv5j1201	152	7	a	a	DT
cord-022561-rv5j1201	152	8	reserve	reserve	NN
cord-022561-rv5j1201	152	9	of	of	IN
cord-022561-rv5j1201	152	10	fully	fully	RB
cord-022561-rv5j1201	152	11	mature	mature	JJ
cord-022561-rv5j1201	152	12	neutrophils	neutrophil	NNS
cord-022561-rv5j1201	152	13	.	.	.
cord-022561-rv5j1201	153	1	The	the	DT
cord-022561-rv5j1201	153	2	size	size	NN
cord-022561-rv5j1201	153	3	of	of	IN
cord-022561-rv5j1201	153	4	the	the	DT
cord-022561-rv5j1201	153	5	storage	storage	NN
cord-022561-rv5j1201	153	6	pool	pool	NN
cord-022561-rv5j1201	153	7	varies	vary	VBZ
cord-022561-rv5j1201	153	8	by	by	IN
cord-022561-rv5j1201	153	9	species	specie	NNS
cord-022561-rv5j1201	153	10	;	;	:
cord-022561-rv5j1201	153	11	it	-PRON-	PRP
cord-022561-rv5j1201	153	12	is	be	VBZ
cord-022561-rv5j1201	153	13	large	large	JJ
cord-022561-rv5j1201	153	14	in	in	IN
cord-022561-rv5j1201	153	15	the	the	DT
cord-022561-rv5j1201	153	16	dog	dog	NN
cord-022561-rv5j1201	153	17	,	,	,
cord-022561-rv5j1201	153	18	but	but	CC
cord-022561-rv5j1201	153	19	small	small	JJ
cord-022561-rv5j1201	153	20	in	in	IN
cord-022561-rv5j1201	153	21	ruminants	ruminant	NNS
cord-022561-rv5j1201	153	22	.	.	.
cord-022561-rv5j1201	154	1	In	in	IN
cord-022561-rv5j1201	154	2	homeostasis	homeostasis	NN
cord-022561-rv5j1201	154	3	mostly	mostly	RB
cord-022561-rv5j1201	154	4	mature	mature	JJ
cord-022561-rv5j1201	154	5	segmented	segmented	JJ
cord-022561-rv5j1201	154	6	granulocytes	granulocyte	NNS
cord-022561-rv5j1201	154	7	are	be	VBP
cord-022561-rv5j1201	154	8	released	release	VBN
cord-022561-rv5j1201	154	9	from	from	IN
cord-022561-rv5j1201	154	10	the	the	DT
cord-022561-rv5j1201	154	11	marrow	marrow	NN
cord-022561-rv5j1201	154	12	into	into	IN
cord-022561-rv5j1201	154	13	the	the	DT
cord-022561-rv5j1201	154	14	blood	blood	NN
cord-022561-rv5j1201	154	15	.	.	.
cord-022561-rv5j1201	155	1	The	the	DT
cord-022561-rv5j1201	155	2	first	first	JJ
cord-022561-rv5j1201	155	3	monocytic	monocytic	JJ
cord-022561-rv5j1201	155	4	precursor	precursor	NN
cord-022561-rv5j1201	155	5	identifiable	identifiable	JJ
cord-022561-rv5j1201	155	6	by	by	IN
cord-022561-rv5j1201	155	7	morphologic	morphologic	JJ
cord-022561-rv5j1201	155	8	features	feature	NNS
cord-022561-rv5j1201	155	9	is	be	VBZ
cord-022561-rv5j1201	155	10	the	the	DT
cord-022561-rv5j1201	155	11	monoblast	monoblast	NN
cord-022561-rv5j1201	155	12	,	,	,
cord-022561-rv5j1201	155	13	which	which	WDT
cord-022561-rv5j1201	155	14	develops	develop	VBZ
cord-022561-rv5j1201	155	15	into	into	IN
cord-022561-rv5j1201	155	16	promonocytes	promonocyte	NNS
cord-022561-rv5j1201	155	17	and	and	CC
cord-022561-rv5j1201	155	18	subsequently	subsequently	RB
cord-022561-rv5j1201	155	19	monocytes	monocyte	VBZ
cord-022561-rv5j1201	155	20	(	(	-LRB-
cord-022561-rv5j1201	155	21	see	see	VB
cord-022561-rv5j1201	155	22	Fig	Fig	NNP
cord-022561-rv5j1201	155	23	.	.	.
cord-022561-rv5j1201	155	24	13	13	CD
cord-022561-rv5j1201	155	25	-3	-3	NNP
cord-022561-rv5j1201	155	26	)	)	-RRB-
cord-022561-rv5j1201	155	27	.	.	.
cord-022561-rv5j1201	156	1	Unlike	unlike	IN
cord-022561-rv5j1201	156	2	granulocytes	granulocyte	NNS
cord-022561-rv5j1201	156	3	,	,	,
cord-022561-rv5j1201	156	4	monocytes	monocyte	NNS
cord-022561-rv5j1201	156	5	do	do	VBP
cord-022561-rv5j1201	156	6	not	not	RB
cord-022561-rv5j1201	156	7	have	have	VB
cord-022561-rv5j1201	156	8	a	a	DT
cord-022561-rv5j1201	156	9	marrow	marrow	NN
cord-022561-rv5j1201	156	10	storage	storage	NN
cord-022561-rv5j1201	156	11	pool	pool	NN
cord-022561-rv5j1201	156	12	;	;	:
cord-022561-rv5j1201	156	13	they	-PRON-	PRP
cord-022561-rv5j1201	156	14	immediately	immediately	RB
cord-022561-rv5j1201	156	15	enter	enter	VBP
cord-022561-rv5j1201	156	16	venous	venous	JJ
cord-022561-rv5j1201	156	17	sinusoids	sinusoid	NNS
cord-022561-rv5j1201	156	18	upon	upon	IN
cord-022561-rv5j1201	156	19	maturation	maturation	NN
cord-022561-rv5j1201	156	20	.	.	.
cord-022561-rv5j1201	157	1	After	after	IN
cord-022561-rv5j1201	157	2	migrating	migrate	VBG
cord-022561-rv5j1201	157	3	into	into	IN
cord-022561-rv5j1201	157	4	the	the	DT
cord-022561-rv5j1201	157	5	tissues	tissue	NNS
cord-022561-rv5j1201	157	6	,	,	,
cord-022561-rv5j1201	157	7	monocytes	monocyte	NNS
cord-022561-rv5j1201	157	8	undergo	undergo	VBP
cord-022561-rv5j1201	157	9	morphologic	morphologic	JJ
cord-022561-rv5j1201	157	10	and	and	CC
cord-022561-rv5j1201	157	11	immunophenotypic	immunophenotypic	JJ
cord-022561-rv5j1201	157	12	maturation	maturation	NN
cord-022561-rv5j1201	157	13	into	into	IN
cord-022561-rv5j1201	157	14	macrophages	macrophage	NNS
cord-022561-rv5j1201	157	15	.	.	.
cord-022561-rv5j1201	158	1	Within	within	IN
cord-022561-rv5j1201	158	2	blood	blood	NN
cord-022561-rv5j1201	158	3	vessels	vessel	NNS
cord-022561-rv5j1201	158	4	there	there	EX
cord-022561-rv5j1201	158	5	are	be	VBP
cord-022561-rv5j1201	158	6	two	two	CD
cord-022561-rv5j1201	158	7	pools	pool	NNS
cord-022561-rv5j1201	158	8	of	of	IN
cord-022561-rv5j1201	158	9	leukocytes	leukocyte	NNS
cord-022561-rv5j1201	158	10	:	:	:
cord-022561-rv5j1201	158	11	the	the	DT
cord-022561-rv5j1201	158	12	circulating	circulate	VBG
cord-022561-rv5j1201	158	13	pool	pool	NN
cord-022561-rv5j1201	158	14	and	and	CC
cord-022561-rv5j1201	158	15	the	the	DT
cord-022561-rv5j1201	158	16	marginating	marginating	NN
cord-022561-rv5j1201	158	17	pool	pool	NN
cord-022561-rv5j1201	158	18	.	.	.
cord-022561-rv5j1201	159	1	Circulating	circulate	VBG
cord-022561-rv5j1201	159	2	cells	cell	NNS
cord-022561-rv5j1201	159	3	are	be	VBP
cord-022561-rv5j1201	159	4	free	free	JJ
cord-022561-rv5j1201	159	5	flowing	flow	VBG
cord-022561-rv5j1201	159	6	in	in	IN
cord-022561-rv5j1201	159	7	blood	blood	NN
cord-022561-rv5j1201	159	8	,	,	,
cord-022561-rv5j1201	159	9	whereas	whereas	IN
cord-022561-rv5j1201	159	10	marginating	marginating	NN
cord-022561-rv5j1201	159	11	cells	cell	NNS
cord-022561-rv5j1201	159	12	are	be	VBP
cord-022561-rv5j1201	159	13	temporarily	temporarily	RB
cord-022561-rv5j1201	159	14	adhered	adhere	VBN
cord-022561-rv5j1201	159	15	to	to	IN
cord-022561-rv5j1201	159	16	endothelial	endothelial	JJ
cord-022561-rv5j1201	159	17	cells	cell	NNS
cord-022561-rv5j1201	159	18	by	by	IN
cord-022561-rv5j1201	159	19	selectins	selectin	NNS
cord-022561-rv5j1201	159	20	.	.	.
cord-022561-rv5j1201	160	1	In	in	IN
cord-022561-rv5j1201	160	2	most	most	RBS
cord-022561-rv5j1201	160	3	healthy	healthy	JJ
cord-022561-rv5j1201	160	4	mammals	mammal	NNS
cord-022561-rv5j1201	160	5	there	there	EX
cord-022561-rv5j1201	160	6	are	be	VBP
cord-022561-rv5j1201	160	7	typically	typically	RB
cord-022561-rv5j1201	160	8	equal	equal	JJ
cord-022561-rv5j1201	160	9	numbers	number	NNS
cord-022561-rv5j1201	160	10	of	of	IN
cord-022561-rv5j1201	160	11	neutrophils	neutrophil	NNS
cord-022561-rv5j1201	160	12	in	in	IN
cord-022561-rv5j1201	160	13	the	the	DT
cord-022561-rv5j1201	160	14	circulating	circulating	JJ
cord-022561-rv5j1201	160	15	and	and	CC
cord-022561-rv5j1201	160	16	marginal	marginal	JJ
cord-022561-rv5j1201	160	17	pools	pool	NNS
cord-022561-rv5j1201	160	18	.	.	.
cord-022561-rv5j1201	161	1	However	however	RB
cord-022561-rv5j1201	161	2	,	,	,
cord-022561-rv5j1201	161	3	there	there	EX
cord-022561-rv5j1201	161	4	are	be	VBP
cord-022561-rv5j1201	161	5	threefold	threefold	RB
cord-022561-rv5j1201	161	6	more	more	RBR
cord-022561-rv5j1201	161	7	marginal	marginal	JJ
cord-022561-rv5j1201	161	8	neutrophils	neutrophil	NNS
cord-022561-rv5j1201	161	9	relative	relative	JJ
cord-022561-rv5j1201	161	10	to	to	IN
cord-022561-rv5j1201	161	11	circulating	circulate	VBG
cord-022561-rv5j1201	161	12	neutrophils	neutrophil	NNS
cord-022561-rv5j1201	161	13	in	in	IN
cord-022561-rv5j1201	161	14	cats	cat	NNS
cord-022561-rv5j1201	161	15	.	.	.
cord-022561-rv5j1201	162	1	Only	only	RB
cord-022561-rv5j1201	162	2	the	the	DT
cord-022561-rv5j1201	162	3	circulating	circulate	VBG
cord-022561-rv5j1201	162	4	leukocyte	leukocyte	NN
cord-022561-rv5j1201	162	5	pool	pool	NN
cord-022561-rv5j1201	162	6	is	be	VBZ
cord-022561-rv5j1201	162	7	sampled	sample	VBN
cord-022561-rv5j1201	162	8	during	during	IN
cord-022561-rv5j1201	162	9	phlebotomy	phlebotomy	NN
cord-022561-rv5j1201	162	10	.	.	.
cord-022561-rv5j1201	163	1	The	the	DT
cord-022561-rv5j1201	163	2	concentration	concentration	NN
cord-022561-rv5j1201	163	3	of	of	IN
cord-022561-rv5j1201	163	4	myeloid	myeloid	NN
cord-022561-rv5j1201	163	5	cells	cell	NNS
cord-022561-rv5j1201	163	6	in	in	IN
cord-022561-rv5j1201	163	7	blood	blood	NN
cord-022561-rv5j1201	163	8	depends	depend	VBZ
cord-022561-rv5j1201	163	9	on	on	IN
cord-022561-rv5j1201	163	10	the	the	DT
cord-022561-rv5j1201	163	11	rate	rate	NN
cord-022561-rv5j1201	163	12	of	of	IN
cord-022561-rv5j1201	163	13	production	production	NN
cord-022561-rv5j1201	163	14	and	and	CC
cord-022561-rv5j1201	163	15	release	release	NN
cord-022561-rv5j1201	163	16	from	from	IN
cord-022561-rv5j1201	163	17	the	the	DT
cord-022561-rv5j1201	163	18	bone	bone	NN
cord-022561-rv5j1201	163	19	marrow	marrow	NN
cord-022561-rv5j1201	163	20	,	,	,
cord-022561-rv5j1201	163	21	the	the	DT
cord-022561-rv5j1201	163	22	proportions	proportion	NNS
cord-022561-rv5j1201	163	23	of	of	IN
cord-022561-rv5j1201	163	24	cells	cell	NNS
cord-022561-rv5j1201	163	25	in	in	IN
cord-022561-rv5j1201	163	26	the	the	DT
cord-022561-rv5j1201	163	27	circulating	circulate	VBG
cord-022561-rv5j1201	163	28	and	and	CC
cord-022561-rv5j1201	163	29	marginating	marginating	NN
cord-022561-rv5j1201	163	30	pools	pool	NNS
cord-022561-rv5j1201	163	31	,	,	,
cord-022561-rv5j1201	163	32	and	and	CC
cord-022561-rv5j1201	163	33	the	the	DT
cord-022561-rv5j1201	163	34	rate	rate	NN
cord-022561-rv5j1201	163	35	of	of	IN
cord-022561-rv5j1201	163	36	migration	migration	NN
cord-022561-rv5j1201	163	37	from	from	IN
cord-022561-rv5j1201	163	38	the	the	DT
cord-022561-rv5j1201	163	39	vasculature	vasculature	NN
cord-022561-rv5j1201	163	40	into	into	IN
cord-022561-rv5j1201	163	41	tissues	tissue	NNS
cord-022561-rv5j1201	163	42	.	.	.
cord-022561-rv5j1201	164	1	The	the	DT
cord-022561-rv5j1201	164	2	fate	fate	NN
cord-022561-rv5j1201	164	3	of	of	IN
cord-022561-rv5j1201	164	4	neutrophils	neutrophil	NNS
cord-022561-rv5j1201	164	5	after	after	IN
cord-022561-rv5j1201	164	6	they	-PRON-	PRP
cord-022561-rv5j1201	164	7	leave	leave	VBP
cord-022561-rv5j1201	164	8	the	the	DT
cord-022561-rv5j1201	164	9	bloodstream	bloodstream	NN
cord-022561-rv5j1201	164	10	in	in	IN
cord-022561-rv5j1201	164	11	normal	normal	JJ
cord-022561-rv5j1201	164	12	conditions	condition	NNS
cord-022561-rv5j1201	164	13	(	(	-LRB-
cord-022561-rv5j1201	164	14	i.e.	i.e.	FW
cord-022561-rv5j1201	164	15	,	,	,
cord-022561-rv5j1201	164	16	not	not	RB
cord-022561-rv5j1201	164	17	in	in	IN
cord-022561-rv5j1201	164	18	the	the	DT
cord-022561-rv5j1201	164	19	context	context	NN
cord-022561-rv5j1201	164	20	of	of	IN
cord-022561-rv5j1201	164	21	inflammation	inflammation	NN
cord-022561-rv5j1201	164	22	)	)	-RRB-
cord-022561-rv5j1201	164	23	is	be	VBZ
cord-022561-rv5j1201	164	24	poorly	poorly	RB
cord-022561-rv5j1201	164	25	understood	understand	VBN
cord-022561-rv5j1201	164	26	.	.	.
cord-022561-rv5j1201	165	1	They	-PRON-	PRP
cord-022561-rv5j1201	165	2	migrate	migrate	VBP
cord-022561-rv5j1201	165	3	into	into	IN
cord-022561-rv5j1201	165	4	the	the	DT
cord-022561-rv5j1201	165	5	gastrointestinal	gastrointestinal	JJ
cord-022561-rv5j1201	165	6	and	and	CC
cord-022561-rv5j1201	165	7	respiratory	respiratory	JJ
cord-022561-rv5j1201	165	8	tracts	tract	NNS
cord-022561-rv5j1201	165	9	,	,	,
cord-022561-rv5j1201	165	10	liver	liver	NN
cord-022561-rv5j1201	165	11	,	,	,
cord-022561-rv5j1201	165	12	and	and	CC
cord-022561-rv5j1201	165	13	spleen	spleen	NN
cord-022561-rv5j1201	165	14	and	and	CC
cord-022561-rv5j1201	165	15	may	may	MD
cord-022561-rv5j1201	165	16	be	be	VB
cord-022561-rv5j1201	165	17	lost	lose	VBN
cord-022561-rv5j1201	165	18	through	through	IN
cord-022561-rv5j1201	165	19	mucosal	mucosal	JJ
cord-022561-rv5j1201	165	20	surfaces	surface	NNS
cord-022561-rv5j1201	165	21	or	or	CC
cord-022561-rv5j1201	165	22	undergo	undergo	VB
cord-022561-rv5j1201	165	23	apoptosis	apoptosis	NN
cord-022561-rv5j1201	165	24	and	and	CC
cord-022561-rv5j1201	165	25	be	be	VB
cord-022561-rv5j1201	165	26	phagocytized	phagocytize	VBN
cord-022561-rv5j1201	165	27	by	by	IN
cord-022561-rv5j1201	165	28	macrophages	macrophage	NNS
cord-022561-rv5j1201	165	29	.	.	.
cord-022561-rv5j1201	166	1	Lymphopoiesis	Lymphopoiesis	NNP
cord-022561-rv5j1201	166	2	.	.	.
cord-022561-rv5j1201	167	1	Lymphopoiesis	lymphopoiesis	NN
cord-022561-rv5j1201	167	2	-	-	HYPH
cord-022561-rv5j1201	167	3	from	from	IN
cord-022561-rv5j1201	167	4	lympha	lympha	NNP
cord-022561-rv5j1201	167	5	(	(	-LRB-
cord-022561-rv5j1201	167	6	Latin	Latin	NNP
cord-022561-rv5j1201	167	7	,	,	,
cord-022561-rv5j1201	167	8	water)refers	water)refers	NNPS
cord-022561-rv5j1201	167	9	to	to	IN
cord-022561-rv5j1201	167	10	the	the	DT
cord-022561-rv5j1201	167	11	production	production	NN
cord-022561-rv5j1201	167	12	of	of	IN
cord-022561-rv5j1201	167	13	new	new	JJ
cord-022561-rv5j1201	167	14	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	167	15	,	,	,
cord-022561-rv5j1201	167	16	including	include	VBG
cord-022561-rv5j1201	167	17	B	b	NN
cord-022561-rv5j1201	167	18	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	167	19	,	,	,
cord-022561-rv5j1201	167	20	T	t	NN
cord-022561-rv5j1201	167	21	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	167	22	,	,	,
cord-022561-rv5j1201	167	23	and	and	CC
cord-022561-rv5j1201	167	24	natural	natural	JJ
cord-022561-rv5j1201	167	25	killer	killer	NN
cord-022561-rv5j1201	167	26	(	(	-LRB-
cord-022561-rv5j1201	167	27	NK	NK	NNP
cord-022561-rv5j1201	167	28	)	)	-RRB-
cord-022561-rv5j1201	167	29	cells	cell	NNS
cord-022561-rv5j1201	167	30	.	.	.
cord-022561-rv5j1201	168	1	B	b	NN
cord-022561-rv5j1201	168	2	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	168	3	primarily	primarily	RB
cord-022561-rv5j1201	168	4	produce	produce	VBP
cord-022561-rv5j1201	168	5	immunoglobulins	immunoglobulin	NNS
cord-022561-rv5j1201	168	6	,	,	,
cord-022561-rv5j1201	168	7	also	also	RB
cord-022561-rv5j1201	168	8	known	know	VBN
cord-022561-rv5j1201	168	9	as	as	IN
cord-022561-rv5j1201	168	10	antibodies	antibody	NNS
cord-022561-rv5j1201	168	11	,	,	,
cord-022561-rv5j1201	168	12	and	and	CC
cord-022561-rv5j1201	168	13	are	be	VBP
cord-022561-rv5j1201	168	14	key	key	JJ
cord-022561-rv5j1201	168	15	effectors	effector	NNS
cord-022561-rv5j1201	168	16	of	of	IN
cord-022561-rv5j1201	168	17	humoral	humoral	JJ
cord-022561-rv5j1201	168	18	immunity	immunity	NN
cord-022561-rv5j1201	168	19	.	.	.
cord-022561-rv5j1201	169	1	They	-PRON-	PRP
cord-022561-rv5j1201	169	2	are	be	VBP
cord-022561-rv5j1201	169	3	distinguished	distinguish	VBN
cord-022561-rv5j1201	169	4	by	by	IN
cord-022561-rv5j1201	169	5	the	the	DT
cord-022561-rv5j1201	169	6	presence	presence	NN
cord-022561-rv5j1201	169	7	of	of	IN
cord-022561-rv5j1201	169	8	an	an	DT
cord-022561-rv5j1201	169	9	immunoglobulin	immunoglobulin	NN
cord-022561-rv5j1201	169	10	receptor	receptor	NN
cord-022561-rv5j1201	169	11	complex	complex	NN
cord-022561-rv5j1201	169	12	,	,	,
cord-022561-rv5j1201	169	13	termed	term	VBD
cord-022561-rv5j1201	169	14	the	the	DT
cord-022561-rv5j1201	169	15	B	b	NN
cord-022561-rv5j1201	169	16	lymphocyte	lymphocyte	NN
cord-022561-rv5j1201	169	17	receptor	receptor	NN
cord-022561-rv5j1201	169	18	.	.	.
cord-022561-rv5j1201	170	1	Plasma	plasma	NN
cord-022561-rv5j1201	170	2	cells	cell	NNS
cord-022561-rv5j1201	170	3	are	be	VBP
cord-022561-rv5j1201	170	4	terminally	terminally	RB
cord-022561-rv5j1201	170	5	differentiated	differentiate	VBN
cord-022561-rv5j1201	170	6	B	b	NN
cord-022561-rv5j1201	170	7	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	170	8	that	that	WDT
cord-022561-rv5j1201	170	9	produce	produce	VBP
cord-022561-rv5j1201	170	10	abundant	abundant	JJ
cord-022561-rv5j1201	170	11	immunoglobulin	immunoglobulin	NN
cord-022561-rv5j1201	170	12	.	.	.
cord-022561-rv5j1201	171	1	T	T	NNP
cord-022561-rv5j1201	171	2	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	171	3	,	,	,
cord-022561-rv5j1201	171	4	effectors	effector	NNS
cord-022561-rv5j1201	171	5	of	of	IN
cord-022561-rv5j1201	171	6	cell	cell	NN
cord-022561-rv5j1201	171	7	-	-	HYPH
cord-022561-rv5j1201	171	8	mediated	mediate	VBN
cord-022561-rv5j1201	171	9	immunity	immunity	NN
cord-022561-rv5j1201	171	10	,	,	,
cord-022561-rv5j1201	171	11	possess	possess	VBP
cord-022561-rv5j1201	171	12	T	T	NNP
cord-022561-rv5j1201	171	13	lymphocyte	lymphocyte	NN
cord-022561-rv5j1201	171	14	receptors	receptor	NNS
cord-022561-rv5j1201	171	15	that	that	WDT
cord-022561-rv5j1201	171	16	bind	bind	VBP
cord-022561-rv5j1201	171	17	antigens	antigen	NNS
cord-022561-rv5j1201	171	18	prepared	prepare	VBN
cord-022561-rv5j1201	171	19	by	by	IN
cord-022561-rv5j1201	171	20	antigen	antigen	NN
cord-022561-rv5j1201	171	21	-	-	HYPH
cord-022561-rv5j1201	171	22	presenting	present	VBG
cord-022561-rv5j1201	171	23	cells	cell	NNS
cord-022561-rv5j1201	171	24	.	.	.
cord-022561-rv5j1201	172	1	A	a	DT
cord-022561-rv5j1201	172	2	component	component	NN
cord-022561-rv5j1201	172	3	of	of	IN
cord-022561-rv5j1201	172	4	innate	innate	JJ
cord-022561-rv5j1201	172	5	immunity	immunity	NN
cord-022561-rv5j1201	172	6	,	,	,
cord-022561-rv5j1201	172	7	NK	NK	NNP
cord-022561-rv5j1201	172	8	cells	cell	NNS
cord-022561-rv5j1201	172	9	kill	kill	VBP
cord-022561-rv5j1201	172	10	a	a	DT
cord-022561-rv5j1201	172	11	variety	variety	NN
cord-022561-rv5j1201	172	12	of	of	IN
cord-022561-rv5j1201	172	13	infected	infected	JJ
cord-022561-rv5j1201	172	14	and	and	CC
cord-022561-rv5j1201	172	15	tumor	tumor	NN
cord-022561-rv5j1201	172	16	cells	cell	NNS
cord-022561-rv5j1201	172	17	in	in	IN
cord-022561-rv5j1201	172	18	the	the	DT
cord-022561-rv5j1201	172	19	absence	absence	NN
cord-022561-rv5j1201	172	20	of	of	IN
cord-022561-rv5j1201	172	21	prior	prior	JJ
cord-022561-rv5j1201	172	22	exposure	exposure	NN
cord-022561-rv5j1201	172	23	or	or	CC
cord-022561-rv5j1201	172	24	priming	priming	NN
cord-022561-rv5j1201	172	25	.	.	.
cord-022561-rv5j1201	173	1	Main	main	JJ
cord-022561-rv5j1201	173	2	growth	growth	NN
cord-022561-rv5j1201	173	3	factors	factor	NNS
cord-022561-rv5j1201	173	4	for	for	IN
cord-022561-rv5j1201	173	5	B	b	NN
cord-022561-rv5j1201	173	6	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	173	7	,	,	,
cord-022561-rv5j1201	173	8	T	t	NN
cord-022561-rv5j1201	173	9	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	173	10	,	,	,
cord-022561-rv5j1201	173	11	and	and	CC
cord-022561-rv5j1201	173	12	NK	NK	NNP
cord-022561-rv5j1201	173	13	cells	cell	NNS
cord-022561-rv5j1201	173	14	are	be	VBP
cord-022561-rv5j1201	173	15	IL-4	IL-4	NNP
cord-022561-rv5j1201	173	16	,	,	,
cord-022561-rv5j1201	173	17	IL-2	IL-2	NNP
cord-022561-rv5j1201	173	18	,	,	,
cord-022561-rv5j1201	173	19	and	and	CC
cord-022561-rv5j1201	173	20	IL-15	IL-15	NNP
cord-022561-rv5j1201	173	21	,	,	,
cord-022561-rv5j1201	173	22	respectively	respectively	RB
cord-022561-rv5j1201	173	23	.	.	.
cord-022561-rv5j1201	174	1	Lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	174	2	are	be	VBP
cord-022561-rv5j1201	174	3	derived	derive	VBN
cord-022561-rv5j1201	174	4	from	from	IN
cord-022561-rv5j1201	174	5	HSCs	hscs	NN
cord-022561-rv5j1201	174	6	within	within	IN
cord-022561-rv5j1201	174	7	the	the	DT
cord-022561-rv5j1201	174	8	bone	bone	NN
cord-022561-rv5j1201	174	9	marrow	marrow	NN
cord-022561-rv5j1201	174	10	.	.	.
cord-022561-rv5j1201	175	1	B	b	NN
cord-022561-rv5j1201	175	2	lymphocyte	lymphocyte	NN
cord-022561-rv5j1201	175	3	development	development	NN
cord-022561-rv5j1201	175	4	occurs	occur	VBZ
cord-022561-rv5j1201	175	5	in	in	IN
cord-022561-rv5j1201	175	6	two	two	CD
cord-022561-rv5j1201	175	7	phases	phase	NNS
cord-022561-rv5j1201	175	8	,	,	,
cord-022561-rv5j1201	175	9	first	first	RB
cord-022561-rv5j1201	175	10	in	in	IN
cord-022561-rv5j1201	175	11	an	an	DT
cord-022561-rv5j1201	175	12	antigenindependent	antigenindependent	NN
cord-022561-rv5j1201	175	13	phase	phase	NN
cord-022561-rv5j1201	175	14	in	in	IN
cord-022561-rv5j1201	175	15	the	the	DT
cord-022561-rv5j1201	175	16	bone	bone	NN
cord-022561-rv5j1201	175	17	marrow	marrow	NN
cord-022561-rv5j1201	175	18	and	and	CC
cord-022561-rv5j1201	175	19	ileal	ileal	JJ
cord-022561-rv5j1201	175	20	Peyer	Peyer	NNP
cord-022561-rv5j1201	175	21	's	's	POS
cord-022561-rv5j1201	175	22	patches	patch	NNS
cord-022561-rv5j1201	175	23	(	(	-LRB-
cord-022561-rv5j1201	175	24	the	the	DT
cord-022561-rv5j1201	175	25	site	site	NN
cord-022561-rv5j1201	175	26	of	of	IN
cord-022561-rv5j1201	175	27	B	b	NN
cord-022561-rv5j1201	175	28	lymphocyte	lymphocyte	NN
cord-022561-rv5j1201	175	29	development	development	NN
cord-022561-rv5j1201	175	30	in	in	IN
cord-022561-rv5j1201	175	31	ruminants	ruminant	NNS
cord-022561-rv5j1201	175	32	)	)	-RRB-
cord-022561-rv5j1201	175	33	,	,	,
cord-022561-rv5j1201	175	34	then	then	RB
cord-022561-rv5j1201	175	35	in	in	IN
cord-022561-rv5j1201	175	36	an	an	DT
cord-022561-rv5j1201	175	37	antigendependent	antigendependent	JJ
cord-022561-rv5j1201	175	38	phase	phase	NN
cord-022561-rv5j1201	175	39	in	in	IN
cord-022561-rv5j1201	175	40	peripheral	peripheral	JJ
cord-022561-rv5j1201	175	41	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	175	42	tissues	tissue	NNS
cord-022561-rv5j1201	175	43	(	(	-LRB-
cord-022561-rv5j1201	175	44	such	such	JJ
cord-022561-rv5j1201	175	45	as	as	IN
cord-022561-rv5j1201	175	46	spleen	spleen	NN
cord-022561-rv5j1201	175	47	,	,	,
cord-022561-rv5j1201	175	48	lymph	lymph	NN
cord-022561-rv5j1201	175	49	nodes	node	NNS
cord-022561-rv5j1201	175	50	,	,	,
cord-022561-rv5j1201	175	51	and	and	CC
cord-022561-rv5j1201	175	52	mucosa	mucosa	NN
cord-022561-rv5j1201	175	53	-	-	HYPH
cord-022561-rv5j1201	175	54	associated	associate	VBN
cord-022561-rv5j1201	175	55	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	175	56	tissue	tissue	NN
cord-022561-rv5j1201	175	57	[	[	-LRB-
cord-022561-rv5j1201	175	58	MALT	malt	NN
cord-022561-rv5j1201	175	59	]	]	-RRB-
cord-022561-rv5j1201	175	60	)	)	-RRB-
cord-022561-rv5j1201	175	61	.	.	.
cord-022561-rv5j1201	176	1	T	T	NNP
cord-022561-rv5j1201	176	2	lymphocyte	lymphocyte	NN
cord-022561-rv5j1201	176	3	progenitors	progenitor	NNS
cord-022561-rv5j1201	176	4	migrate	migrate	VBP
cord-022561-rv5j1201	176	5	from	from	IN
cord-022561-rv5j1201	176	6	the	the	DT
cord-022561-rv5j1201	176	7	bone	bone	NN
cord-022561-rv5j1201	176	8	marrow	marrow	NN
cord-022561-rv5j1201	176	9	to	to	IN
cord-022561-rv5j1201	176	10	the	the	DT
cord-022561-rv5j1201	176	11	thymus	thymus	NN
cord-022561-rv5j1201	176	12	,	,	,
cord-022561-rv5j1201	176	13	where	where	WRB
cord-022561-rv5j1201	176	14	they	-PRON-	PRP
cord-022561-rv5j1201	176	15	undergo	undergo	VBP
cord-022561-rv5j1201	176	16	differentiation	differentiation	NN
cord-022561-rv5j1201	176	17	,	,	,
cord-022561-rv5j1201	176	18	selection	selection	NN
cord-022561-rv5j1201	176	19	,	,	,
cord-022561-rv5j1201	176	20	and	and	CC
cord-022561-rv5j1201	176	21	maturation	maturation	NN
cord-022561-rv5j1201	176	22	processes	process	NNS
cord-022561-rv5j1201	176	23	before	before	IN
cord-022561-rv5j1201	176	24	migrating	migrate	VBG
cord-022561-rv5j1201	176	25	to	to	IN
cord-022561-rv5j1201	176	26	the	the	DT
cord-022561-rv5j1201	176	27	peripheral	peripheral	JJ
cord-022561-rv5j1201	176	28	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	176	29	tissue	tissue	NN
cord-022561-rv5j1201	176	30	as	as	IN
cord-022561-rv5j1201	176	31	effector	effector	NN
cord-022561-rv5j1201	176	32	cells	cell	NNS
cord-022561-rv5j1201	176	33	.	.	.
cord-022561-rv5j1201	177	1	Unlike	unlike	IN
cord-022561-rv5j1201	177	2	granulocytes	granulocyte	NNS
cord-022561-rv5j1201	177	3	,	,	,
cord-022561-rv5j1201	177	4	which	which	WDT
cord-022561-rv5j1201	177	5	circulate	circulate	VBP
cord-022561-rv5j1201	177	6	only	only	RB
cord-022561-rv5j1201	177	7	in	in	IN
cord-022561-rv5j1201	177	8	blood	blood	NN
cord-022561-rv5j1201	177	9	vessels	vessel	NNS
cord-022561-rv5j1201	177	10	and	and	CC
cord-022561-rv5j1201	177	11	migrate	migrate	VB
cord-022561-rv5j1201	177	12	unidirectionally	unidirectionally	RB
cord-022561-rv5j1201	177	13	into	into	IN
cord-022561-rv5j1201	177	14	target	target	NN
cord-022561-rv5j1201	177	15	tissues	tissue	NNS
cord-022561-rv5j1201	177	16	,	,	,
cord-022561-rv5j1201	177	17	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	177	18	travel	travel	VBP
cord-022561-rv5j1201	177	19	in	in	IN
cord-022561-rv5j1201	177	20	both	both	CC
cord-022561-rv5j1201	177	21	blood	blood	NN
cord-022561-rv5j1201	177	22	and	and	CC
cord-022561-rv5j1201	177	23	lymphatic	lymphatic	NN
cord-022561-rv5j1201	177	24	vessels	vessel	NNS
cord-022561-rv5j1201	177	25	and	and	CC
cord-022561-rv5j1201	177	26	continually	continually	RB
cord-022561-rv5j1201	177	27	circulate	circulate	VBP
cord-022561-rv5j1201	177	28	between	between	IN
cord-022561-rv5j1201	177	29	blood	blood	NN
cord-022561-rv5j1201	177	30	,	,	,
cord-022561-rv5j1201	177	31	tissues	tissue	NNS
cord-022561-rv5j1201	177	32	,	,	,
cord-022561-rv5j1201	177	33	and	and	CC
cord-022561-rv5j1201	177	34	lymphatic	lymphatic	JJ
cord-022561-rv5j1201	177	35	vessels	vessel	NNS
cord-022561-rv5j1201	177	36	.	.	.
cord-022561-rv5j1201	178	1	Also	also	RB
cord-022561-rv5j1201	178	2	in	in	IN
cord-022561-rv5j1201	178	3	contrast	contrast	NN
cord-022561-rv5j1201	178	4	to	to	IN
cord-022561-rv5j1201	178	5	nonlymphoid	nonlymphoid	NNP
cord-022561-rv5j1201	178	6	hematopoietic	hematopoietic	JJ
cord-022561-rv5j1201	178	7	cells	cell	NNS
cord-022561-rv5j1201	178	8	,	,	,
cord-022561-rv5j1201	178	9	blood	blood	NN
cord-022561-rv5j1201	178	10	lymphocyte	lymphocyte	NN
cord-022561-rv5j1201	178	11	concentrations	concentration	NNS
cord-022561-rv5j1201	178	12	in	in	IN
cord-022561-rv5j1201	178	13	adult	adult	NN
cord-022561-rv5j1201	178	14	animals	animal	NNS
cord-022561-rv5j1201	178	15	are	be	VBP
cord-022561-rv5j1201	178	16	primarily	primarily	RB
cord-022561-rv5j1201	178	17	dependent	dependent	JJ
cord-022561-rv5j1201	178	18	upon	upon	IN
cord-022561-rv5j1201	178	19	extramedullary	extramedullary	JJ
cord-022561-rv5j1201	178	20	lymphocyte	lymphocyte	NN
cord-022561-rv5j1201	178	21	production	production	NN
cord-022561-rv5j1201	178	22	and	and	CC
cord-022561-rv5j1201	178	23	kinetics	kinetics	NN
cord-022561-rv5j1201	178	24	,	,	,
cord-022561-rv5j1201	178	25	and	and	CC
cord-022561-rv5j1201	178	26	not	not	RB
cord-022561-rv5j1201	178	27	lymphopoiesis	lymphopoiesis	NN
cord-022561-rv5j1201	178	28	by	by	IN
cord-022561-rv5j1201	178	29	the	the	DT
cord-022561-rv5j1201	178	30	marrow	marrow	NN
cord-022561-rv5j1201	178	31	.	.	.
cord-022561-rv5j1201	179	1	In	in	IN
cord-022561-rv5j1201	179	2	healthy	healthy	JJ
cord-022561-rv5j1201	179	3	nonruminant	nonruminant	JJ
cord-022561-rv5j1201	179	4	mammals	mammal	NNS
cord-022561-rv5j1201	179	5	,	,	,
cord-022561-rv5j1201	179	6	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	179	7	are	be	VBP
cord-022561-rv5j1201	179	8	the	the	DT
cord-022561-rv5j1201	179	9	second	second	JJ
cord-022561-rv5j1201	179	10	most	most	RBS
cord-022561-rv5j1201	179	11	numerous	numerous	JJ
cord-022561-rv5j1201	179	12	blood	blood	NN
cord-022561-rv5j1201	179	13	leukocyte	leukocyte	NN
cord-022561-rv5j1201	179	14	.	.	.
cord-022561-rv5j1201	180	1	According	accord	VBG
cord-022561-rv5j1201	180	2	to	to	IN
cord-022561-rv5j1201	180	3	conventional	conventional	JJ
cord-022561-rv5j1201	180	4	wisdom	wisdom	NN
cord-022561-rv5j1201	180	5	,	,	,
cord-022561-rv5j1201	180	6	•	•	NN
cord-022561-rv5j1201	180	7	Decreased	decrease	VBD
cord-022561-rv5j1201	180	8	erythrocyte	erythrocyte	NN
cord-022561-rv5j1201	180	9	deformability	deformability	NN
cord-022561-rv5j1201	180	10	.	.	.
cord-022561-rv5j1201	181	1	•	•	NNP
cord-022561-rv5j1201	182	1	Binding	bind	VBG
cord-022561-rv5j1201	182	2	of	of	IN
cord-022561-rv5j1201	182	3	immunoglobulin	immunoglobulin	NN
cord-022561-rv5j1201	182	4	G	G	NNP
cord-022561-rv5j1201	182	5	(	(	-LRB-
cord-022561-rv5j1201	182	6	IgG	IgG	NNP
cord-022561-rv5j1201	182	7	)	)	-RRB-
cord-022561-rv5j1201	182	8	and/or	and/or	CC
cord-022561-rv5j1201	182	9	complement	complement	VB
cord-022561-rv5j1201	182	10	to	to	IN
cord-022561-rv5j1201	182	11	erythrocyte	erythrocyte	NN
cord-022561-rv5j1201	182	12	membranes	membrane	NNS
cord-022561-rv5j1201	182	13	.	.	.
cord-022561-rv5j1201	183	1	Complement	complement	JJ
cord-022561-rv5j1201	183	2	binding	binding	NN
cord-022561-rv5j1201	183	3	may	may	MD
cord-022561-rv5j1201	183	4	be	be	VB
cord-022561-rv5j1201	183	5	secondary	secondary	JJ
cord-022561-rv5j1201	183	6	clustering	clustering	NN
cord-022561-rv5j1201	183	7	of	of	IN
cord-022561-rv5j1201	183	8	the	the	DT
cord-022561-rv5j1201	183	9	membrane	membrane	NN
cord-022561-rv5j1201	183	10	anion	anion	NN
cord-022561-rv5j1201	183	11	exchange	exchange	NN
cord-022561-rv5j1201	183	12	protein	protein	NN
cord-022561-rv5j1201	183	13	,	,	,
cord-022561-rv5j1201	183	14	band	band	NN
cord-022561-rv5j1201	183	15	3	3	CD
cord-022561-rv5j1201	183	16	.	.	.
cord-022561-rv5j1201	184	1	•	•	NNP
cord-022561-rv5j1201	185	1	Oxidative	oxidative	JJ
cord-022561-rv5j1201	185	2	damage	damage	NN
cord-022561-rv5j1201	185	3	to	to	IN
cord-022561-rv5j1201	185	4	erythrocytes	erythrocyte	NNS
cord-022561-rv5j1201	185	5	.	.	.
cord-022561-rv5j1201	186	1	Macrophages	macrophage	NNS
cord-022561-rv5j1201	186	2	degrade	degrade	VBP
cord-022561-rv5j1201	186	3	erythrocytes	erythrocyte	NNS
cord-022561-rv5j1201	186	4	into	into	IN
cord-022561-rv5j1201	186	5	reusable	reusable	JJ
cord-022561-rv5j1201	186	6	components	component	NNS
cord-022561-rv5j1201	186	7	,	,	,
cord-022561-rv5j1201	186	8	such	such	JJ
cord-022561-rv5j1201	186	9	as	as	IN
cord-022561-rv5j1201	186	10	iron	iron	NN
cord-022561-rv5j1201	186	11	and	and	CC
cord-022561-rv5j1201	186	12	amino	amino	JJ
cord-022561-rv5j1201	186	13	acids	acid	NNS
cord-022561-rv5j1201	186	14	,	,	,
cord-022561-rv5j1201	186	15	and	and	CC
cord-022561-rv5j1201	186	16	the	the	DT
cord-022561-rv5j1201	186	17	waste	waste	NN
cord-022561-rv5j1201	186	18	product	product	NN
cord-022561-rv5j1201	186	19	bilirubin	bilirubin	NN
cord-022561-rv5j1201	186	20	.	.	.
cord-022561-rv5j1201	187	1	Bilirubin	bilirubin	NN
cord-022561-rv5j1201	187	2	is	be	VBZ
cord-022561-rv5j1201	187	3	then	then	RB
cord-022561-rv5j1201	187	4	exported	export	VBN
cord-022561-rv5j1201	187	5	into	into	IN
cord-022561-rv5j1201	187	6	circulation	circulation	NN
cord-022561-rv5j1201	187	7	,	,	,
cord-022561-rv5j1201	187	8	where	where	WRB
cord-022561-rv5j1201	187	9	it	-PRON-	PRP
cord-022561-rv5j1201	187	10	is	be	VBZ
cord-022561-rv5j1201	187	11	transported	transport	VBN
cord-022561-rv5j1201	187	12	to	to	IN
cord-022561-rv5j1201	187	13	the	the	DT
cord-022561-rv5j1201	187	14	liver	liver	NN
cord-022561-rv5j1201	187	15	by	by	IN
cord-022561-rv5j1201	187	16	albumin	albumin	NN
cord-022561-rv5j1201	187	17	.	.	.
cord-022561-rv5j1201	188	1	The	the	DT
cord-022561-rv5j1201	188	2	liver	liver	NN
cord-022561-rv5j1201	188	3	conjugates	conjugate	NNS
cord-022561-rv5j1201	188	4	and	and	CC
cord-022561-rv5j1201	188	5	subsequently	subsequently	RB
cord-022561-rv5j1201	188	6	excretes	excrete	VBZ
cord-022561-rv5j1201	188	7	bilirubin	bilirubin	NN
cord-022561-rv5j1201	188	8	into	into	IN
cord-022561-rv5j1201	188	9	bile	bile	NN
cord-022561-rv5j1201	188	10	for	for	IN
cord-022561-rv5j1201	188	11	elimination	elimination	NN
cord-022561-rv5j1201	188	12	from	from	IN
cord-022561-rv5j1201	188	13	the	the	DT
cord-022561-rv5j1201	188	14	body	body	NN
cord-022561-rv5j1201	188	15	.	.	.
cord-022561-rv5j1201	189	1	Intravascular	intravascular	JJ
cord-022561-rv5j1201	189	2	hemolysis	hemolysis	NN
cord-022561-rv5j1201	189	3	normally	normally	RB
cord-022561-rv5j1201	189	4	occurs	occur	VBZ
cord-022561-rv5j1201	189	5	at	at	IN
cord-022561-rv5j1201	189	6	only	only	RB
cord-022561-rv5j1201	189	7	extremely	extremely	RB
cord-022561-rv5j1201	189	8	low	low	JJ
cord-022561-rv5j1201	189	9	levels	level	NNS
cord-022561-rv5j1201	189	10	.	.	.
cord-022561-rv5j1201	190	1	Hemoglobin	hemoglobin	NN
cord-022561-rv5j1201	190	2	is	be	VBZ
cord-022561-rv5j1201	190	3	a	a	DT
cord-022561-rv5j1201	190	4	tetramer	tetramer	NN
cord-022561-rv5j1201	190	5	that	that	IN
cord-022561-rv5j1201	190	6	,	,	,
cord-022561-rv5j1201	190	7	when	when	WRB
cord-022561-rv5j1201	190	8	released	release	VBN
cord-022561-rv5j1201	190	9	from	from	IN
cord-022561-rv5j1201	190	10	the	the	DT
cord-022561-rv5j1201	190	11	erythrocyte	erythrocyte	NN
cord-022561-rv5j1201	190	12	into	into	IN
cord-022561-rv5j1201	190	13	the	the	DT
cord-022561-rv5j1201	190	14	blood	blood	NN
cord-022561-rv5j1201	190	15	,	,	,
cord-022561-rv5j1201	190	16	splits	split	VBZ
cord-022561-rv5j1201	190	17	into	into	IN
cord-022561-rv5j1201	190	18	dimers	dimer	NNS
cord-022561-rv5j1201	190	19	that	that	WDT
cord-022561-rv5j1201	190	20	bind	bind	VBP
cord-022561-rv5j1201	190	21	to	to	IN
cord-022561-rv5j1201	190	22	a	a	DT
cord-022561-rv5j1201	190	23	plasma	plasma	NN
cord-022561-rv5j1201	190	24	protein	protein	NN
cord-022561-rv5j1201	190	25	called	call	VBN
cord-022561-rv5j1201	190	26	haptoglobin	haptoglobin	NN
cord-022561-rv5j1201	190	27	.	.	.
cord-022561-rv5j1201	191	1	The	the	DT
cord-022561-rv5j1201	191	2	hemoglobin	hemoglobin	NN
cord-022561-rv5j1201	191	3	-	-	HYPH
cord-022561-rv5j1201	191	4	haptoglobin	haptoglobin	NN
cord-022561-rv5j1201	191	5	complex	complex	NN
cord-022561-rv5j1201	191	6	is	be	VBZ
cord-022561-rv5j1201	191	7	taken	take	VBN
cord-022561-rv5j1201	191	8	up	up	RP
cord-022561-rv5j1201	191	9	by	by	IN
cord-022561-rv5j1201	191	10	hepatocytes	hepatocyte	NNS
cord-022561-rv5j1201	191	11	and	and	CC
cord-022561-rv5j1201	191	12	macrophages	macrophage	NNS
cord-022561-rv5j1201	191	13	.	.	.
cord-022561-rv5j1201	192	1	This	this	DT
cord-022561-rv5j1201	192	2	is	be	VBZ
cord-022561-rv5j1201	192	3	the	the	DT
cord-022561-rv5j1201	192	4	major	major	JJ
cord-022561-rv5j1201	192	5	pathway	pathway	NN
cord-022561-rv5j1201	192	6	for	for	IN
cord-022561-rv5j1201	192	7	handling	handle	VBG
cord-022561-rv5j1201	192	8	free	free	JJ
cord-022561-rv5j1201	192	9	hemoglobin	hemoglobin	NN
cord-022561-rv5j1201	192	10	.	.	.
cord-022561-rv5j1201	193	1	However	however	RB
cord-022561-rv5j1201	193	2	,	,	,
cord-022561-rv5j1201	193	3	free	free	JJ
cord-022561-rv5j1201	193	4	hemoglobin	hemoglobin	NN
cord-022561-rv5j1201	193	5	may	may	MD
cord-022561-rv5j1201	193	6	also	also	RB
cord-022561-rv5j1201	193	7	oxidize	oxidize	VB
cord-022561-rv5j1201	193	8	to	to	TO
cord-022561-rv5j1201	193	9	form	form	VB
cord-022561-rv5j1201	193	10	methemoglobin	methemoglobin	NNP
cord-022561-rv5j1201	193	11	,	,	,
cord-022561-rv5j1201	193	12	which	which	WDT
cord-022561-rv5j1201	193	13	dissociates	dissociate	VBZ
cord-022561-rv5j1201	193	14	to	to	TO
cord-022561-rv5j1201	193	15	form	form	VB
cord-022561-rv5j1201	193	16	metheme	metheme	NNP
cord-022561-rv5j1201	193	17	and	and	CC
cord-022561-rv5j1201	193	18	globin	globin	NN
cord-022561-rv5j1201	193	19	.	.	.
cord-022561-rv5j1201	194	1	Metheme	Metheme	NNP
cord-022561-rv5j1201	194	2	binds	bind	VBZ
cord-022561-rv5j1201	194	3	to	to	IN
cord-022561-rv5j1201	194	4	a	a	DT
cord-022561-rv5j1201	194	5	plasma	plasma	NN
cord-022561-rv5j1201	194	6	protein	protein	NN
cord-022561-rv5j1201	194	7	called	call	VBN
cord-022561-rv5j1201	194	8	hemopexin	hemopexin	NNP
cord-022561-rv5j1201	194	9	,	,	,
cord-022561-rv5j1201	194	10	which	which	WDT
cord-022561-rv5j1201	194	11	is	be	VBZ
cord-022561-rv5j1201	194	12	taken	take	VBN
cord-022561-rv5j1201	194	13	up	up	RP
cord-022561-rv5j1201	194	14	by	by	IN
cord-022561-rv5j1201	194	15	hepatocytes	hepatocyte	NNS
cord-022561-rv5j1201	194	16	and	and	CC
cord-022561-rv5j1201	194	17	macrophages	macrophage	NNS
cord-022561-rv5j1201	194	18	in	in	IN
cord-022561-rv5j1201	194	19	a	a	DT
cord-022561-rv5j1201	194	20	similar	similar	JJ
cord-022561-rv5j1201	194	21	manner	manner	NN
cord-022561-rv5j1201	194	22	to	to	IN
cord-022561-rv5j1201	194	23	hemoglobin	hemoglobin	NN
cord-022561-rv5j1201	194	24	-	-	HYPH
cord-022561-rv5j1201	194	25	haptoglobin	haptoglobin	NN
cord-022561-rv5j1201	194	26	complexes	complex	NNS
cord-022561-rv5j1201	194	27	.	.	.
cord-022561-rv5j1201	195	1	Free	free	JJ
cord-022561-rv5j1201	195	2	heme	heme	NN
cord-022561-rv5j1201	195	3	in	in	IN
cord-022561-rv5j1201	195	4	the	the	DT
cord-022561-rv5j1201	195	5	reduced	reduce	VBN
cord-022561-rv5j1201	195	6	form	form	NN
cord-022561-rv5j1201	195	7	binds	bind	VBZ
cord-022561-rv5j1201	195	8	to	to	IN
cord-022561-rv5j1201	195	9	albumin	albumin	NN
cord-022561-rv5j1201	195	10	,	,	,
cord-022561-rv5j1201	195	11	from	from	IN
cord-022561-rv5j1201	195	12	which	which	WDT
cord-022561-rv5j1201	195	13	it	-PRON-	PRP
cord-022561-rv5j1201	195	14	is	be	VBZ
cord-022561-rv5j1201	195	15	taken	take	VBN
cord-022561-rv5j1201	195	16	up	up	RP
cord-022561-rv5j1201	195	17	in	in	IN
cord-022561-rv5j1201	195	18	the	the	DT
cord-022561-rv5j1201	195	19	liver	liver	NN
cord-022561-rv5j1201	195	20	and	and	CC
cord-022561-rv5j1201	195	21	converted	convert	VBD
cord-022561-rv5j1201	195	22	into	into	IN
cord-022561-rv5j1201	195	23	bilirubin	bilirubin	NN
cord-022561-rv5j1201	195	24	.	.	.
cord-022561-rv5j1201	196	1	The	the	DT
cord-022561-rv5j1201	196	2	concentration	concentration	NN
cord-022561-rv5j1201	196	3	of	of	IN
cord-022561-rv5j1201	196	4	circulating	circulate	VBG
cord-022561-rv5j1201	196	5	erythrocytes	erythrocyte	NNS
cord-022561-rv5j1201	196	6	typically	typically	RB
cord-022561-rv5j1201	196	7	decreases	decrease	VBZ
cord-022561-rv5j1201	196	8	postnatally	postnatally	NN
cord-022561-rv5j1201	196	9	and	and	CC
cord-022561-rv5j1201	196	10	remains	remain	VBZ
cord-022561-rv5j1201	196	11	below	below	IN
cord-022561-rv5j1201	196	12	normal	normal	JJ
cord-022561-rv5j1201	196	13	adult	adult	NN
cord-022561-rv5j1201	196	14	levels	level	NNS
cord-022561-rv5j1201	196	15	during	during	IN
cord-022561-rv5j1201	196	16	the	the	DT
cord-022561-rv5j1201	196	17	period	period	NN
cord-022561-rv5j1201	196	18	of	of	IN
cord-022561-rv5j1201	196	19	rapid	rapid	JJ
cord-022561-rv5j1201	196	20	body	body	NN
cord-022561-rv5j1201	196	21	growth	growth	NN
cord-022561-rv5j1201	196	22	.	.	.
cord-022561-rv5j1201	197	1	The	the	DT
cord-022561-rv5j1201	197	2	age	age	NN
cord-022561-rv5j1201	197	3	at	at	IN
cord-022561-rv5j1201	197	4	which	which	WDT
cord-022561-rv5j1201	197	5	erythrocyte	erythrocyte	NN
cord-022561-rv5j1201	197	6	numbers	number	NNS
cord-022561-rv5j1201	197	7	begin	begin	VBP
cord-022561-rv5j1201	197	8	to	to	TO
cord-022561-rv5j1201	197	9	increase	increase	VB
cord-022561-rv5j1201	197	10	and	and	CC
cord-022561-rv5j1201	197	11	the	the	DT
cord-022561-rv5j1201	197	12	age	age	NN
cord-022561-rv5j1201	197	13	at	at	IN
cord-022561-rv5j1201	197	14	which	which	WDT
cord-022561-rv5j1201	197	15	adult	adult	NN
cord-022561-rv5j1201	197	16	levels	level	NNS
cord-022561-rv5j1201	197	17	are	be	VBP
cord-022561-rv5j1201	197	18	reached	reach	VBN
cord-022561-rv5j1201	197	19	vary	vary	VBP
cord-022561-rv5j1201	197	20	among	among	IN
cord-022561-rv5j1201	197	21	species	specie	NNS
cord-022561-rv5j1201	197	22	.	.	.
cord-022561-rv5j1201	198	1	In	in	IN
cord-022561-rv5j1201	198	2	dogs	dog	NNS
cord-022561-rv5j1201	198	3	,	,	,
cord-022561-rv5j1201	198	4	adult	adult	NN
cord-022561-rv5j1201	198	5	values	value	NNS
cord-022561-rv5j1201	198	6	are	be	VBP
cord-022561-rv5j1201	198	7	usually	usually	RB
cord-022561-rv5j1201	198	8	reached	reach	VBN
cord-022561-rv5j1201	198	9	between	between	IN
cord-022561-rv5j1201	198	10	4	4	CD
cord-022561-rv5j1201	198	11	and	and	CC
cord-022561-rv5j1201	198	12	6	6	CD
cord-022561-rv5j1201	198	13	months	month	NNS
cord-022561-rv5j1201	198	14	of	of	IN
cord-022561-rv5j1201	198	15	age	age	NN
cord-022561-rv5j1201	198	16	;	;	:
cord-022561-rv5j1201	198	17	in	in	IN
cord-022561-rv5j1201	198	18	horses	horse	NNS
cord-022561-rv5j1201	198	19	,	,	,
cord-022561-rv5j1201	198	20	this	this	DT
cord-022561-rv5j1201	198	21	occurs	occur	VBZ
cord-022561-rv5j1201	198	22	at	at	IN
cord-022561-rv5j1201	198	23	approximately	approximately	RB
cord-022561-rv5j1201	198	24	1	1	CD
cord-022561-rv5j1201	198	25	year	year	NN
cord-022561-rv5j1201	198	26	of	of	IN
cord-022561-rv5j1201	198	27	age	age	NN
cord-022561-rv5j1201	198	28	.	.	.
cord-022561-rv5j1201	199	1	Granulopoiesis	granulopoiesis	NN
cord-022561-rv5j1201	199	2	is	be	VBZ
cord-022561-rv5j1201	199	3	the	the	DT
cord-022561-rv5j1201	199	4	production	production	NN
cord-022561-rv5j1201	199	5	of	of	IN
cord-022561-rv5j1201	199	6	neutrophils	neutrophil	NNS
cord-022561-rv5j1201	199	7	,	,	,
cord-022561-rv5j1201	199	8	eosinophils	eosinophil	NNS
cord-022561-rv5j1201	199	9	,	,	,
cord-022561-rv5j1201	199	10	and	and	CC
cord-022561-rv5j1201	199	11	basophils	basophil	NNS
cord-022561-rv5j1201	199	12	,	,	,
cord-022561-rv5j1201	199	13	whereas	whereas	IN
cord-022561-rv5j1201	199	14	monocyte	monocyte	NNP
cord-022561-rv5j1201	199	15	production	production	NN
cord-022561-rv5j1201	199	16	is	be	VBZ
cord-022561-rv5j1201	199	17	termed	term	VBN
cord-022561-rv5j1201	199	18	monocytopoiesis	monocytopoiesis	NN
cord-022561-rv5j1201	199	19	.	.	.
cord-022561-rv5j1201	200	1	Granulocytic	granulocytic	JJ
cord-022561-rv5j1201	200	2	and	and	CC
cord-022561-rv5j1201	200	3	monocytic	monocytic	JJ
cord-022561-rv5j1201	200	4	cells	cell	NNS
cord-022561-rv5j1201	200	5	are	be	VBP
cord-022561-rv5j1201	200	6	sometimes	sometimes	RB
cord-022561-rv5j1201	200	7	collectively	collectively	RB
cord-022561-rv5j1201	200	8	referenced	reference	VBN
cord-022561-rv5j1201	200	9	as	as	IN
cord-022561-rv5j1201	200	10	myeloid	myeloid	NN
cord-022561-rv5j1201	200	11	cells	cell	NNS
cord-022561-rv5j1201	200	12	.	.	.
cord-022561-rv5j1201	201	1	However	however	RB
cord-022561-rv5j1201	201	2	,	,	,
cord-022561-rv5j1201	201	3	the	the	DT
cord-022561-rv5j1201	201	4	term	term	NN
cord-022561-rv5j1201	201	5	myeloid	myeloid	JJ
cord-022561-rv5j1201	201	6	and	and	CC
cord-022561-rv5j1201	201	7	the	the	DT
cord-022561-rv5j1201	201	8	prefix	prefix	NN
cord-022561-rv5j1201	201	9	myelo	myelo	NN
cord-022561-rv5j1201	201	10	-	-	,
cord-022561-rv5j1201	201	11	can	can	MD
cord-022561-rv5j1201	201	12	be	be	VB
cord-022561-rv5j1201	201	13	confusing	confusing	JJ
cord-022561-rv5j1201	201	14	because	because	IN
cord-022561-rv5j1201	201	15	they	-PRON-	PRP
cord-022561-rv5j1201	201	16	have	have	VBP
cord-022561-rv5j1201	201	17	other	other	JJ
cord-022561-rv5j1201	201	18	meanings	meaning	NNS
cord-022561-rv5j1201	201	19	;	;	:
cord-022561-rv5j1201	201	20	they	-PRON-	PRP
cord-022561-rv5j1201	201	21	may	may	MD
cord-022561-rv5j1201	201	22	reference	reference	VB
cord-022561-rv5j1201	201	23	the	the	DT
cord-022561-rv5j1201	201	24	bone	bone	NN
cord-022561-rv5j1201	201	25	marrow	marrow	NN
cord-022561-rv5j1201	201	26	,	,	,
cord-022561-rv5j1201	201	27	all	all	DT
cord-022561-rv5j1201	201	28	nonlymphoid	nonlymphoid	NNP
cord-022561-rv5j1201	201	29	hemic	hemic	NNP
cord-022561-rv5j1201	201	30	cells	cell	NNS
cord-022561-rv5j1201	201	31	(	(	-LRB-
cord-022561-rv5j1201	201	32	erythrocytes	erythrocyte	NNS
cord-022561-rv5j1201	201	33	,	,	,
cord-022561-rv5j1201	201	34	leukocytes	leukocyte	NNS
cord-022561-rv5j1201	201	35	,	,	,
cord-022561-rv5j1201	201	36	and	and	CC
cord-022561-rv5j1201	201	37	megakaryocytes	megakaryocytes	NNP
cord-022561-rv5j1201	201	38	)	)	-RRB-
cord-022561-rv5j1201	201	39	,	,	,
cord-022561-rv5j1201	201	40	only	only	RB
cord-022561-rv5j1201	201	41	granulocytes	granulocyte	NNS
cord-022561-rv5j1201	201	42	,	,	,
cord-022561-rv5j1201	201	43	or	or	CC
cord-022561-rv5j1201	201	44	the	the	DT
cord-022561-rv5j1201	201	45	spinal	spinal	JJ
cord-022561-rv5j1201	201	46	cord	cord	NN
cord-022561-rv5j1201	201	47	.	.	.
cord-022561-rv5j1201	202	1	The	the	DT
cord-022561-rv5j1201	202	2	main	main	JJ
cord-022561-rv5j1201	202	3	purpose	purpose	NN
cord-022561-rv5j1201	202	4	of	of	IN
cord-022561-rv5j1201	202	5	granulocytes	granulocyte	NNS
cord-022561-rv5j1201	202	6	and	and	CC
cord-022561-rv5j1201	202	7	monocytes	monocyte	NNS
cord-022561-rv5j1201	202	8	is	be	VBZ
cord-022561-rv5j1201	202	9	to	to	TO
cord-022561-rv5j1201	202	10	migrate	migrate	VB
cord-022561-rv5j1201	202	11	to	to	IN
cord-022561-rv5j1201	202	12	sites	site	NNS
cord-022561-rv5j1201	202	13	of	of	IN
cord-022561-rv5j1201	202	14	tissue	tissue	NN
cord-022561-rv5j1201	202	15	inflammation	inflammation	NN
cord-022561-rv5j1201	202	16	and	and	CC
cord-022561-rv5j1201	202	17	function	function	NN
cord-022561-rv5j1201	202	18	in	in	IN
cord-022561-rv5j1201	202	19	host	host	NN
cord-022561-rv5j1201	202	20	defense	defense	NN
cord-022561-rv5j1201	202	21	(	(	-LRB-
cord-022561-rv5j1201	202	22	see	see	VB
cord-022561-rv5j1201	202	23	Chapters	chapter	NNS
cord-022561-rv5j1201	202	24	3	3	CD
cord-022561-rv5j1201	202	25	and	and	CC
cord-022561-rv5j1201	202	26	5	5	CD
cord-022561-rv5j1201	202	27	)	)	-RRB-
cord-022561-rv5j1201	202	28	.	.	.
cord-022561-rv5j1201	203	1	Briefly	briefly	RB
cord-022561-rv5j1201	203	2	,	,	,
cord-022561-rv5j1201	203	3	these	these	DT
cord-022561-rv5j1201	203	4	cells	cell	NNS
cord-022561-rv5j1201	203	5	have	have	VBP
cord-022561-rv5j1201	203	6	key	key	JJ
cord-022561-rv5j1201	203	7	immunologic	immunologic	JJ
cord-022561-rv5j1201	203	8	functions	function	NNS
cord-022561-rv5j1201	203	9	,	,	,
cord-022561-rv5j1201	203	10	including	include	VBG
cord-022561-rv5j1201	203	11	phagocytosis	phagocytosis	NN
cord-022561-rv5j1201	203	12	and	and	CC
cord-022561-rv5j1201	203	13	microbicidal	microbicidal	NN
cord-022561-rv5j1201	203	14	activity	activity	NN
cord-022561-rv5j1201	203	15	(	(	-LRB-
cord-022561-rv5j1201	203	16	neutrophils	neutrophil	NNS
cord-022561-rv5j1201	203	17	and	and	CC
cord-022561-rv5j1201	203	18	monocyte	monocyte	NN
cord-022561-rv5j1201	203	19	-	-	HYPH
cord-022561-rv5j1201	203	20	derived	derive	VBN
cord-022561-rv5j1201	203	21	macrophages	macrophage	NNS
cord-022561-rv5j1201	203	22	)	)	-RRB-
cord-022561-rv5j1201	203	23	,	,	,
cord-022561-rv5j1201	203	24	parasiticidal	parasiticidal	JJ
cord-022561-rv5j1201	203	25	activity	activity	NN
cord-022561-rv5j1201	203	26	and	and	CC
cord-022561-rv5j1201	203	27	participation	participation	NN
cord-022561-rv5j1201	203	28	in	in	IN
cord-022561-rv5j1201	203	29	allergic	allergic	JJ
cord-022561-rv5j1201	203	30	reactions	reaction	NNS
cord-022561-rv5j1201	203	31	(	(	-LRB-
cord-022561-rv5j1201	203	32	eosinophils	eosinophil	NNS
cord-022561-rv5j1201	203	33	and	and	CC
cord-022561-rv5j1201	203	34	basophils	basophil	NNS
cord-022561-rv5j1201	203	35	)	)	-RRB-
cord-022561-rv5j1201	203	36	,	,	,
cord-022561-rv5j1201	203	37	antigen	antigen	NN
cord-022561-rv5j1201	203	38	processing	processing	NN
cord-022561-rv5j1201	203	39	and	and	CC
cord-022561-rv5j1201	203	40	presentation	presentation	NN
cord-022561-rv5j1201	203	41	,	,	,
cord-022561-rv5j1201	203	42	and	and	CC
cord-022561-rv5j1201	203	43	cytokine	cytokine	NN
cord-022561-rv5j1201	203	44	production	production	NN
cord-022561-rv5j1201	203	45	(	(	-LRB-
cord-022561-rv5j1201	203	46	macrophages	macrophage	NNS
cord-022561-rv5j1201	203	47	)	)	-RRB-
cord-022561-rv5j1201	203	48	.	.	.
cord-022561-rv5j1201	204	1	Neutrophils	neutrophil	NNS
cord-022561-rv5j1201	204	2	are	be	VBP
cord-022561-rv5j1201	204	3	the	the	DT
cord-022561-rv5j1201	204	4	predominant	predominant	JJ
cord-022561-rv5j1201	204	5	leukocyte	leukocyte	NN
cord-022561-rv5j1201	204	6	type	type	NN
cord-022561-rv5j1201	204	7	in	in	IN
cord-022561-rv5j1201	204	8	blood	blood	NN
cord-022561-rv5j1201	204	9	of	of	IN
cord-022561-rv5j1201	204	10	most	most	JJS
cord-022561-rv5j1201	204	11	domestic	domestic	JJ
cord-022561-rv5j1201	204	12	species	specie	NNS
cord-022561-rv5j1201	204	13	.	.	.
cord-022561-rv5j1201	205	1	Primary	primary	JJ
cord-022561-rv5j1201	205	2	stimulators	stimulator	NNS
cord-022561-rv5j1201	205	3	of	of	IN
cord-022561-rv5j1201	205	4	granulopoiesis	granulopoiesis	NNP
cord-022561-rv5j1201	205	5	and	and	CC
cord-022561-rv5j1201	205	6	monocytopoiesis	monocytopoiesis	NNP
cord-022561-rv5j1201	205	7	are	be	VBP
cord-022561-rv5j1201	205	8	granulocyte	granulocyte	NN
cord-022561-rv5j1201	205	9	-	-	HYPH
cord-022561-rv5j1201	205	10	macrophage	macrophage	NN
cord-022561-rv5j1201	205	11	colony	colony	NN
cord-022561-rv5j1201	205	12	-	-	HYPH
cord-022561-rv5j1201	205	13	stimulating	stimulate	VBG
cord-022561-rv5j1201	205	14	factor	factor	NN
cord-022561-rv5j1201	205	15	and	and	CC
cord-022561-rv5j1201	205	16	IL-1	IL-1	NNP
cord-022561-rv5j1201	205	17	,	,	,
cord-022561-rv5j1201	205	18	IL-3	IL-3	NNP
cord-022561-rv5j1201	205	19	,	,	,
cord-022561-rv5j1201	205	20	and	and	CC
cord-022561-rv5j1201	205	21	IL-6	IL-6	NNP
cord-022561-rv5j1201	205	22	(	(	-LRB-
cord-022561-rv5j1201	205	23	granulocytes	granulocyte	NNS
cord-022561-rv5j1201	205	24	and	and	CC
cord-022561-rv5j1201	205	25	monocytes	monocyte	NNS
cord-022561-rv5j1201	205	26	)	)	-RRB-
cord-022561-rv5j1201	205	27	,	,	,
cord-022561-rv5j1201	205	28	granulocyte	granulocyte	NNP
cord-022561-rv5j1201	205	29	colonystimulating	colonystimulating	NN
cord-022561-rv5j1201	205	30	factor	factor	NN
cord-022561-rv5j1201	205	31	(	(	-LRB-
cord-022561-rv5j1201	205	32	granulocytes	granulocyte	NNS
cord-022561-rv5j1201	205	33	)	)	-RRB-
cord-022561-rv5j1201	205	34	,	,	,
cord-022561-rv5j1201	205	35	and	and	CC
cord-022561-rv5j1201	205	36	macrophage	macrophage	NN
cord-022561-rv5j1201	205	37	colonystimulating	colonystimulating	NN
cord-022561-rv5j1201	205	38	factor	factor	NN
cord-022561-rv5j1201	205	39	(	(	-LRB-
cord-022561-rv5j1201	205	40	monocytes	monocyte	NNS
cord-022561-rv5j1201	205	41	)	)	-RRB-
cord-022561-rv5j1201	205	42	.	.	.
cord-022561-rv5j1201	206	1	In	in	IN
cord-022561-rv5j1201	206	2	general	general	JJ
cord-022561-rv5j1201	206	3	,	,	,
cord-022561-rv5j1201	206	4	these	these	DT
cord-022561-rv5j1201	206	5	cytokines	cytokine	NNS
cord-022561-rv5j1201	206	6	are	be	VBP
cord-022561-rv5j1201	206	7	produced	produce	VBN
cord-022561-rv5j1201	206	8	by	by	IN
cord-022561-rv5j1201	206	9	various	various	JJ
cord-022561-rv5j1201	206	10	inflammatory	inflammatory	JJ
cord-022561-rv5j1201	206	11	cells	cell	NNS
cord-022561-rv5j1201	206	12	,	,	,
cord-022561-rv5j1201	206	13	with	with	IN
cord-022561-rv5j1201	206	14	or	or	CC
cord-022561-rv5j1201	206	15	without	without	IN
cord-022561-rv5j1201	206	16	contribution	contribution	NN
cord-022561-rv5j1201	206	17	from	from	IN
cord-022561-rv5j1201	206	18	stromal	stromal	JJ
cord-022561-rv5j1201	206	19	cells	cell	NNS
cord-022561-rv5j1201	206	20	.	.	.
cord-022561-rv5j1201	207	1	The	the	DT
cord-022561-rv5j1201	207	2	earliest	early	JJS
cord-022561-rv5j1201	207	3	granulocytic	granulocytic	JJ
cord-022561-rv5j1201	207	4	precursor	precursor	NN
cord-022561-rv5j1201	207	5	identifiable	identifiable	JJ
cord-022561-rv5j1201	207	6	by	by	IN
cord-022561-rv5j1201	207	7	routine	routine	JJ
cord-022561-rv5j1201	207	8	light	light	JJ
cord-022561-rv5j1201	207	9	microscopy	microscopy	NN
cord-022561-rv5j1201	207	10	is	be	VBZ
cord-022561-rv5j1201	207	11	the	the	DT
cord-022561-rv5j1201	207	12	myeloblast	myeloblast	JJS
cord-022561-rv5j1201	207	13	,	,	,
cord-022561-rv5j1201	207	14	which	which	WDT
cord-022561-rv5j1201	207	15	undergoes	undergo	VBZ
cord-022561-rv5j1201	207	16	maturational	maturational	JJ
cord-022561-rv5j1201	207	17	division	division	NN
cord-022561-rv5j1201	207	18	over	over	IN
cord-022561-rv5j1201	207	19	5	5	CD
cord-022561-rv5j1201	207	20	days	day	NNS
cord-022561-rv5j1201	207	21	to	to	TO
cord-022561-rv5j1201	207	22	produce	produce	VB
cord-022561-rv5j1201	207	23	16	16	CD
cord-022561-rv5j1201	207	24	to	to	TO
cord-022561-rv5j1201	207	25	32	32	CD
cord-022561-rv5j1201	207	26	progeny	progeny	NN
cord-022561-rv5j1201	207	27	cells	cell	NNS
cord-022561-rv5j1201	207	28	(	(	-LRB-
cord-022561-rv5j1201	207	29	see	see	VB
cord-022561-rv5j1201	207	30	Fig	Fig	NNP
cord-022561-rv5j1201	207	31	.	.	.
cord-022561-rv5j1201	208	1	13	13	CD
cord-022561-rv5j1201	208	2	-3	-3	NNP
cord-022561-rv5j1201	208	3	)	)	-RRB-
cord-022561-rv5j1201	208	4	.	.	.
cord-022561-rv5j1201	209	1	These	these	DT
cord-022561-rv5j1201	209	2	granulocytic	granulocytic	JJ
cord-022561-rv5j1201	209	3	precursors	precursor	NNS
cord-022561-rv5j1201	209	4	are	be	VBP
cord-022561-rv5j1201	209	5	conceptually	conceptually	RB
cord-022561-rv5j1201	209	6	divided	divide	VBN
cord-022561-rv5j1201	209	7	into	into	IN
cord-022561-rv5j1201	209	8	those	those	DT
cord-022561-rv5j1201	209	9	stages	stage	NNS
cord-022561-rv5j1201	209	10	that	that	WDT
cord-022561-rv5j1201	209	11	can	can	MD
cord-022561-rv5j1201	209	12	divide	divide	VB
cord-022561-rv5j1201	209	13	,	,	,
cord-022561-rv5j1201	209	14	including	include	VBG
cord-022561-rv5j1201	209	15	myeloblasts	myeloblast	NNS
cord-022561-rv5j1201	209	16	,	,	,
cord-022561-rv5j1201	209	17	promyelocytes	promyelocyte	NNS
cord-022561-rv5j1201	209	18	,	,	,
cord-022561-rv5j1201	209	19	and	and	CC
cord-022561-rv5j1201	209	20	myelocytes	myelocytes	FW
cord-022561-rv5j1201	209	21	(	(	-LRB-
cord-022561-rv5j1201	209	22	proliferation	proliferation	NN
cord-022561-rv5j1201	209	23	pool	pool	NN
cord-022561-rv5j1201	209	24	)	)	-RRB-
cord-022561-rv5j1201	209	25	,	,	,
cord-022561-rv5j1201	209	26	and	and	CC
cord-022561-rv5j1201	209	27	those	those	DT
cord-022561-rv5j1201	209	28	that	that	WDT
cord-022561-rv5j1201	209	29	can	can	MD
cord-022561-rv5j1201	209	30	not	not	RB
cord-022561-rv5j1201	209	31	,	,	,
cord-022561-rv5j1201	209	32	including	include	VBG
cord-022561-rv5j1201	209	33	metamyelocytes	metamyelocyte	NNS
cord-022561-rv5j1201	209	34	,	,	,
cord-022561-rv5j1201	209	35	and	and	CC
cord-022561-rv5j1201	209	36	band	band	NN
cord-022561-rv5j1201	209	37	and	and	CC
cord-022561-rv5j1201	209	38	segmented	segmented	JJ
cord-022561-rv5j1201	209	39	forms	form	NNS
cord-022561-rv5j1201	209	40	(	(	-LRB-
cord-022561-rv5j1201	209	41	maturation	maturation	NN
cord-022561-rv5j1201	209	42	pool	pool	NN
cord-022561-rv5j1201	209	43	)	)	-RRB-
cord-022561-rv5j1201	209	44	.	.	.
cord-022561-rv5j1201	210	1	Within	within	IN
cord-022561-rv5j1201	210	2	the	the	DT
cord-022561-rv5j1201	210	3	neutrophil	neutrophil	NN
cord-022561-rv5j1201	210	4	maturation	maturation	NN
cord-022561-rv5j1201	210	5	pool	pool	NN
cord-022561-rv5j1201	210	6	is	be	VBZ
cord-022561-rv5j1201	210	7	a	a	DT
cord-022561-rv5j1201	210	8	subpool	subpool	NN
cord-022561-rv5j1201	210	9	,	,	,
cord-022561-rv5j1201	210	10	termed	term	VBD
cord-022561-rv5j1201	210	11	the	the	DT
cord-022561-rv5j1201	210	12	platelet	platelet	NN
cord-022561-rv5j1201	210	13	aggregation	aggregation	NN
cord-022561-rv5j1201	210	14	and	and	CC
cord-022561-rv5j1201	210	15	adherence	adherence	NN
cord-022561-rv5j1201	210	16	to	to	IN
cord-022561-rv5j1201	210	17	subendothelial	subendothelial	JJ
cord-022561-rv5j1201	210	18	collagen	collagen	NN
cord-022561-rv5j1201	210	19	.	.	.
cord-022561-rv5j1201	211	1	Expansion	expansion	NN
cord-022561-rv5j1201	211	2	of	of	IN
cord-022561-rv5j1201	211	3	surface	surface	NN
cord-022561-rv5j1201	211	4	area	area	NN
cord-022561-rv5j1201	211	5	and	and	CC
cord-022561-rv5j1201	211	6	release	release	NN
cord-022561-rv5j1201	211	7	of	of	IN
cord-022561-rv5j1201	211	8	granule	granule	NN
cord-022561-rv5j1201	211	9	contents	content	NNS
cord-022561-rv5j1201	211	10	is	be	VBZ
cord-022561-rv5j1201	211	11	aided	aid	VBN
cord-022561-rv5j1201	211	12	by	by	IN
cord-022561-rv5j1201	211	13	a	a	DT
cord-022561-rv5j1201	211	14	network	network	NN
cord-022561-rv5j1201	211	15	of	of	IN
cord-022561-rv5j1201	211	16	membrane	membrane	NN
cord-022561-rv5j1201	211	17	invaginations	invagination	NNS
cord-022561-rv5j1201	211	18	known	know	VBN
cord-022561-rv5j1201	211	19	as	as	IN
cord-022561-rv5j1201	211	20	the	the	DT
cord-022561-rv5j1201	211	21	open	open	JJ
cord-022561-rv5j1201	211	22	canalicular	canalicular	JJ
cord-022561-rv5j1201	211	23	system	system	NN
cord-022561-rv5j1201	211	24	.	.	.
cord-022561-rv5j1201	212	1	This	this	DT
cord-022561-rv5j1201	212	2	system	system	NN
cord-022561-rv5j1201	212	3	is	be	VBZ
cord-022561-rv5j1201	212	4	not	not	RB
cord-022561-rv5j1201	212	5	present	present	JJ
cord-022561-rv5j1201	212	6	in	in	IN
cord-022561-rv5j1201	212	7	horses	horse	NNS
cord-022561-rv5j1201	212	8	,	,	,
cord-022561-rv5j1201	212	9	cattle	cattle	NNS
cord-022561-rv5j1201	212	10	,	,	,
cord-022561-rv5j1201	212	11	and	and	CC
cord-022561-rv5j1201	212	12	camelids	camelid	NNS
cord-022561-rv5j1201	212	13	.	.	.
cord-022561-rv5j1201	213	1	Information	information	NN
cord-022561-rv5j1201	213	2	on	on	IN
cord-022561-rv5j1201	213	3	this	this	DT
cord-022561-rv5j1201	213	4	topic	topic	NN
cord-022561-rv5j1201	213	5	is	be	VBZ
cord-022561-rv5j1201	213	6	available	available	JJ
cord-022561-rv5j1201	213	7	at	at	IN
cord-022561-rv5j1201	213	8	www.expertconsult.com	www.expertconsult.com	ADD
cord-022561-rv5j1201	213	9	.	.	.
cord-022561-rv5j1201	214	1	Information	information	NN
cord-022561-rv5j1201	214	2	on	on	IN
cord-022561-rv5j1201	214	3	this	this	DT
cord-022561-rv5j1201	214	4	topic	topic	NN
cord-022561-rv5j1201	214	5	is	be	VBZ
cord-022561-rv5j1201	214	6	available	available	JJ
cord-022561-rv5j1201	214	7	at	at	IN
cord-022561-rv5j1201	214	8	www.expertconsult.com	www.expertconsult.com	ADD
cord-022561-rv5j1201	214	9	.	.	.
cord-022561-rv5j1201	215	1	Information	information	NN
cord-022561-rv5j1201	215	2	on	on	IN
cord-022561-rv5j1201	215	3	this	this	DT
cord-022561-rv5j1201	215	4	topic	topic	NN
cord-022561-rv5j1201	215	5	is	be	VBZ
cord-022561-rv5j1201	215	6	available	available	JJ
cord-022561-rv5j1201	215	7	at	at	IN
cord-022561-rv5j1201	215	8	www.expertconsult.com	www.expertconsult.com	ADD
cord-022561-rv5j1201	215	9	.	.	.
cord-022561-rv5j1201	216	1	Information	information	NN
cord-022561-rv5j1201	216	2	on	on	IN
cord-022561-rv5j1201	216	3	this	this	DT
cord-022561-rv5j1201	216	4	topic	topic	NN
cord-022561-rv5j1201	216	5	is	be	VBZ
cord-022561-rv5j1201	216	6	available	available	JJ
cord-022561-rv5j1201	216	7	at	at	IN
cord-022561-rv5j1201	216	8	www.expertconsult.com	www.expertconsult.com	ADD
cord-022561-rv5j1201	216	9	.	.	.
cord-022561-rv5j1201	217	1	Mechanisms	mechanism	NNS
cord-022561-rv5j1201	217	2	of	of	IN
cord-022561-rv5j1201	217	3	bone	bone	NN
cord-022561-rv5j1201	217	4	marrow	marrow	NN
cord-022561-rv5j1201	217	5	disease	disease	NN
cord-022561-rv5j1201	217	6	are	be	VBP
cord-022561-rv5j1201	217	7	summarized	summarize	VBN
cord-022561-rv5j1201	217	8	in	in	IN
cord-022561-rv5j1201	217	9	Box	Box	NNP
cord-022561-rv5j1201	217	10	13	13	CD
cord-022561-rv5j1201	217	11	-	-	SYM
cord-022561-rv5j1201	217	12	1	1	CD
cord-022561-rv5j1201	217	13	.	.	.
cord-022561-rv5j1201	218	1	Hematopoietic	Hematopoietic	NNP
cord-022561-rv5j1201	218	2	cells	cell	NNS
cord-022561-rv5j1201	218	3	'	'	POS
cord-022561-rv5j1201	218	4	response	response	NN
cord-022561-rv5j1201	218	5	to	to	IN
cord-022561-rv5j1201	218	6	injury	injury	NN
cord-022561-rv5j1201	218	7	is	be	VBZ
cord-022561-rv5j1201	218	8	dependent	dependent	JJ
cord-022561-rv5j1201	218	9	upon	upon	IN
cord-022561-rv5j1201	218	10	whether	whether	IN
cord-022561-rv5j1201	218	11	the	the	DT
cord-022561-rv5j1201	218	12	insult	insult	NN
cord-022561-rv5j1201	218	13	is	be	VBZ
cord-022561-rv5j1201	218	14	on	on	IN
cord-022561-rv5j1201	218	15	the	the	DT
cord-022561-rv5j1201	218	16	marrow	marrow	NN
cord-022561-rv5j1201	218	17	or	or	CC
cord-022561-rv5j1201	218	18	within	within	IN
cord-022561-rv5j1201	218	19	extramarrow	extramarrow	NN
cord-022561-rv5j1201	218	20	tissues	tissue	NNS
cord-022561-rv5j1201	218	21	.	.	.
cord-022561-rv5j1201	219	1	In	in	IN
cord-022561-rv5j1201	219	2	general	general	JJ
cord-022561-rv5j1201	219	3	,	,	,
cord-022561-rv5j1201	219	4	marrow	marrow	NN
cord-022561-rv5j1201	219	5	-	-	HYPH
cord-022561-rv5j1201	219	6	directed	direct	VBN
cord-022561-rv5j1201	219	7	injury	injury	NN
cord-022561-rv5j1201	219	8	or	or	CC
cord-022561-rv5j1201	219	9	disturbances	disturbance	NNS
cord-022561-rv5j1201	219	10	result	result	VBP
cord-022561-rv5j1201	219	11	in	in	IN
cord-022561-rv5j1201	219	12	production	production	NN
cord-022561-rv5j1201	219	13	of	of	IN
cord-022561-rv5j1201	219	14	abnormal	abnormal	JJ
cord-022561-rv5j1201	219	15	hematopoietic	hematopoietic	JJ
cord-022561-rv5j1201	219	16	cells	cell	NNS
cord-022561-rv5j1201	219	17	(	(	-LRB-
cord-022561-rv5j1201	219	18	dysplasia	dysplasia	NN
cord-022561-rv5j1201	219	19	)	)	-RRB-
cord-022561-rv5j1201	219	20	,	,	,
cord-022561-rv5j1201	219	21	fewer	few	JJR
cord-022561-rv5j1201	219	22	hematopoietic	hematopoietic	JJ
cord-022561-rv5j1201	219	23	cells	cell	NNS
cord-022561-rv5j1201	219	24	(	(	-LRB-
cord-022561-rv5j1201	219	25	hypoplasia	hypoplasia	NN
cord-022561-rv5j1201	219	26	)	)	-RRB-
cord-022561-rv5j1201	219	27	,	,	,
cord-022561-rv5j1201	219	28	or	or	CC
cord-022561-rv5j1201	219	29	a	a	DT
cord-022561-rv5j1201	219	30	failure	failure	NN
cord-022561-rv5j1201	219	31	of	of	IN
cord-022561-rv5j1201	219	32	hematopoietic	hematopoietic	JJ
cord-022561-rv5j1201	219	33	cell	cell	NN
cord-022561-rv5j1201	219	34	development	development	NN
cord-022561-rv5j1201	219	35	(	(	-LRB-
cord-022561-rv5j1201	219	36	aplasia	aplasia	NNP
cord-022561-rv5j1201	219	37	)	)	-RRB-
cord-022561-rv5j1201	219	38	.	.	.
cord-022561-rv5j1201	220	1	Dysplasia	dysplasia	NN
cord-022561-rv5j1201	220	2	,	,	,
cord-022561-rv5j1201	220	3	hypoplasia	hypoplasia	NN
cord-022561-rv5j1201	220	4	,	,	,
cord-022561-rv5j1201	220	5	and	and	CC
cord-022561-rv5j1201	220	6	aplasia	aplasia	NNP
cord-022561-rv5j1201	220	7	may	may	MD
cord-022561-rv5j1201	220	8	be	be	VB
cord-022561-rv5j1201	220	9	specific	specific	JJ
cord-022561-rv5j1201	220	10	for	for	IN
cord-022561-rv5j1201	220	11	one	one	CD
cord-022561-rv5j1201	220	12	cell	cell	NN
cord-022561-rv5j1201	220	13	line	line	NN
cord-022561-rv5j1201	220	14	,	,	,
cord-022561-rv5j1201	220	15	such	such	JJ
cord-022561-rv5j1201	220	16	as	as	IN
cord-022561-rv5j1201	220	17	pure	pure	JJ
cord-022561-rv5j1201	220	18	red	red	JJ
cord-022561-rv5j1201	220	19	cell	cell	NN
cord-022561-rv5j1201	220	20	aplasia	aplasia	NNP
cord-022561-rv5j1201	220	21	,	,	,
cord-022561-rv5j1201	220	22	or	or	CC
cord-022561-rv5j1201	220	23	affect	affect	VB
cord-022561-rv5j1201	220	24	multiple	multiple	JJ
cord-022561-rv5j1201	220	25	lineages	lineage	NNS
cord-022561-rv5j1201	220	26	,	,	,
cord-022561-rv5j1201	220	27	as	as	IN
cord-022561-rv5j1201	220	28	seen	see	VBN
cord-022561-rv5j1201	220	29	with	with	IN
cord-022561-rv5j1201	220	30	aplastic	aplastic	JJ
cord-022561-rv5j1201	220	31	anemia	anemia	NN
cord-022561-rv5j1201	220	32	.	.	.
cord-022561-rv5j1201	221	1	Accordingly	accordingly	RB
cord-022561-rv5j1201	221	2	,	,	,
cord-022561-rv5j1201	221	3	decreased	decrease	VBD
cord-022561-rv5j1201	221	4	blood	blood	NN
cord-022561-rv5j1201	221	5	concentrations	concentration	NNS
cord-022561-rv5j1201	221	6	of	of	IN
cord-022561-rv5j1201	221	7	the	the	DT
cord-022561-rv5j1201	221	8	involved	involved	JJ
cord-022561-rv5j1201	221	9	cell	cell	NN
cord-022561-rv5j1201	221	10	types	type	NNS
cord-022561-rv5j1201	221	11	are	be	VBP
cord-022561-rv5j1201	221	12	expected	expect	VBN
cord-022561-rv5j1201	221	13	with	with	IN
cord-022561-rv5j1201	221	14	hypoplasia	hypoplasia	NN
cord-022561-rv5j1201	221	15	or	or	CC
cord-022561-rv5j1201	221	16	aplasia	aplasia	NNP
cord-022561-rv5j1201	221	17	.	.	.
cord-022561-rv5j1201	222	1	Erythroid	Erythroid	NNP
cord-022561-rv5j1201	222	2	,	,	,
cord-022561-rv5j1201	222	3	myeloid	myeloid	NN
cord-022561-rv5j1201	222	4	,	,	,
cord-022561-rv5j1201	222	5	and	and	CC
cord-022561-rv5j1201	222	6	megakaryocytic	megakaryocytic	JJ
cord-022561-rv5j1201	222	7	hypoplasia	hypoplasia	NNP
cord-022561-rv5j1201	222	8	or	or	CC
cord-022561-rv5j1201	222	9	aplasia	aplasia	NNP
cord-022561-rv5j1201	222	10	causes	cause	VBZ
cord-022561-rv5j1201	222	11	nonregenerative	nonregenerative	JJ
cord-022561-rv5j1201	222	12	anemia	anemia	NN
cord-022561-rv5j1201	222	13	,	,	,
cord-022561-rv5j1201	222	14	neutropenia	neutropenia	NN
cord-022561-rv5j1201	222	15	,	,	,
cord-022561-rv5j1201	222	16	and	and	CC
cord-022561-rv5j1201	222	17	thrombocytopenia	thrombocytopenia	NN
cord-022561-rv5j1201	222	18	,	,	,
cord-022561-rv5j1201	222	19	respectively	respectively	RB
cord-022561-rv5j1201	222	20	.	.	.
cord-022561-rv5j1201	223	1	Bicytopenia	Bicytopenia	NNP
cord-022561-rv5j1201	223	2	is	be	VBZ
cord-022561-rv5j1201	223	3	used	use	VBN
cord-022561-rv5j1201	223	4	to	to	TO
cord-022561-rv5j1201	223	5	describe	describe	VB
cord-022561-rv5j1201	223	6	decreased	decrease	VBN
cord-022561-rv5j1201	223	7	blood	blood	NN
cord-022561-rv5j1201	223	8	concentrations	concentration	NNS
cord-022561-rv5j1201	223	9	of	of	IN
cord-022561-rv5j1201	223	10	two	two	CD
cord-022561-rv5j1201	223	11	cell	cell	NN
cord-022561-rv5j1201	223	12	lines	line	NNS
cord-022561-rv5j1201	223	13	,	,	,
cord-022561-rv5j1201	223	14	whereas	whereas	IN
cord-022561-rv5j1201	223	15	pancytopenia	pancytopenia	NNP
cord-022561-rv5j1201	223	16	indicates	indicate	VBZ
cord-022561-rv5j1201	223	17	decreased	decrease	VBN
cord-022561-rv5j1201	223	18	blood	blood	NN
cord-022561-rv5j1201	223	19	concentrations	concentration	NNS
cord-022561-rv5j1201	223	20	of	of	IN
cord-022561-rv5j1201	223	21	all	all	DT
cord-022561-rv5j1201	223	22	three	three	CD
cord-022561-rv5j1201	223	23	cell	cell	NN
cord-022561-rv5j1201	223	24	types	type	NNS
cord-022561-rv5j1201	223	25	.	.	.
cord-022561-rv5j1201	224	1	Bicytopenia	Bicytopenia	NNP
cord-022561-rv5j1201	224	2	or	or	CC
cord-022561-rv5j1201	224	3	pancytopenia	pancytopenia	NNP
cord-022561-rv5j1201	224	4	may	may	MD
cord-022561-rv5j1201	224	5	indicate	indicate	VB
cord-022561-rv5j1201	224	6	generalized	generalized	JJ
cord-022561-rv5j1201	224	7	marrow	marrow	NN
cord-022561-rv5j1201	224	8	disease	disease	NN
cord-022561-rv5j1201	224	9	,	,	,
cord-022561-rv5j1201	224	10	such	such	JJ
cord-022561-rv5j1201	224	11	as	as	IN
cord-022561-rv5j1201	224	12	occurs	occur	VBZ
cord-022561-rv5j1201	224	13	with	with	IN
cord-022561-rv5j1201	224	14	aplastic	aplastic	JJ
cord-022561-rv5j1201	224	15	anemia	anemia	NN
cord-022561-rv5j1201	224	16	or	or	CC
cord-022561-rv5j1201	224	17	marrow	marrow	NN
cord-022561-rv5j1201	224	18	malignancies	malignancy	NNS
cord-022561-rv5j1201	224	19	(	(	-LRB-
cord-022561-rv5j1201	224	20	leukemia	leukemia	NN
cord-022561-rv5j1201	224	21	)	)	-RRB-
cord-022561-rv5j1201	224	22	,	,	,
cord-022561-rv5j1201	224	23	necrosis	necrosis	NN
cord-022561-rv5j1201	224	24	,	,	,
cord-022561-rv5j1201	224	25	fibrosis	fibrosis	NN
cord-022561-rv5j1201	224	26	(	(	-LRB-
cord-022561-rv5j1201	224	27	myelofibrosis	myelofibrosis	NNP
cord-022561-rv5j1201	224	28	)	)	-RRB-
cord-022561-rv5j1201	224	29	,	,	,
cord-022561-rv5j1201	224	30	or	or	CC
cord-022561-rv5j1201	224	31	inflammation	inflammation	NN
cord-022561-rv5j1201	224	32	(	(	-LRB-
cord-022561-rv5j1201	224	33	myelitis	myelitis	NNP
cord-022561-rv5j1201	224	34	)	)	-RRB-
cord-022561-rv5j1201	224	35	.	.	.
cord-022561-rv5j1201	225	1	Replacement	replacement	NN
cord-022561-rv5j1201	225	2	of	of	IN
cord-022561-rv5j1201	225	3	hematopoietic	hematopoietic	JJ
cord-022561-rv5j1201	225	4	tissue	tissue	NN
cord-022561-rv5j1201	225	5	within	within	IN
cord-022561-rv5j1201	225	6	the	the	DT
cord-022561-rv5j1201	225	7	bone	bone	NN
cord-022561-rv5j1201	225	8	marrow	marrow	NN
cord-022561-rv5j1201	225	9	by	by	IN
cord-022561-rv5j1201	225	10	abnormal	abnormal	JJ
cord-022561-rv5j1201	225	11	tissue	tissue	NN
cord-022561-rv5j1201	225	12	,	,	,
cord-022561-rv5j1201	225	13	including	include	VBG
cord-022561-rv5j1201	225	14	neoplastic	neoplastic	JJ
cord-022561-rv5j1201	225	15	cells	cell	NNS
cord-022561-rv5j1201	225	16	,	,	,
cord-022561-rv5j1201	225	17	fibrosis	fibrosis	NN
cord-022561-rv5j1201	225	18	,	,	,
cord-022561-rv5j1201	225	19	or	or	CC
cord-022561-rv5j1201	225	20	inflammatory	inflammatory	JJ
cord-022561-rv5j1201	225	21	cells	cell	NNS
cord-022561-rv5j1201	225	22	,	,	,
cord-022561-rv5j1201	225	23	is	be	VBZ
cord-022561-rv5j1201	225	24	termed	term	VBN
cord-022561-rv5j1201	225	25	myelophthisis	myelophthisis	NN
cord-022561-rv5j1201	225	26	.	.	.
cord-022561-rv5j1201	226	1	cattle	cattle	NNS
cord-022561-rv5j1201	226	2	normally	normally	RB
cord-022561-rv5j1201	226	3	have	have	VBP
cord-022561-rv5j1201	226	4	higher	high	JJR
cord-022561-rv5j1201	226	5	numbers	number	NNS
cord-022561-rv5j1201	226	6	of	of	IN
cord-022561-rv5j1201	226	7	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	226	8	than	than	IN
cord-022561-rv5j1201	226	9	neutrophils	neutrophil	NNS
cord-022561-rv5j1201	226	10	in	in	IN
cord-022561-rv5j1201	226	11	circulation	circulation	NN
cord-022561-rv5j1201	226	12	.	.	.
cord-022561-rv5j1201	227	1	However	however	RB
cord-022561-rv5j1201	227	2	,	,	,
cord-022561-rv5j1201	227	3	recent	recent	JJ
cord-022561-rv5j1201	227	4	studies	study	NNS
cord-022561-rv5j1201	227	5	suggest	suggest	VBP
cord-022561-rv5j1201	227	6	that	that	DT
cord-022561-rv5j1201	227	7	is	be	VBZ
cord-022561-rv5j1201	227	8	no	no	RB
cord-022561-rv5j1201	227	9	longer	long	RBR
cord-022561-rv5j1201	227	10	the	the	DT
cord-022561-rv5j1201	227	11	case	case	NN
cord-022561-rv5j1201	227	12	,	,	,
cord-022561-rv5j1201	227	13	most	most	RBS
cord-022561-rv5j1201	227	14	likely	likely	JJ
cord-022561-rv5j1201	227	15	due	due	JJ
cord-022561-rv5j1201	227	16	to	to	IN
cord-022561-rv5j1201	227	17	changes	change	NNS
cord-022561-rv5j1201	227	18	in	in	IN
cord-022561-rv5j1201	227	19	genetics	genetic	NNS
cord-022561-rv5j1201	227	20	and	and	CC
cord-022561-rv5j1201	227	21	husbandry	husbandry	NN
cord-022561-rv5j1201	227	22	.	.	.
cord-022561-rv5j1201	228	1	In	in	IN
cord-022561-rv5j1201	228	2	most	most	JJS
cord-022561-rv5j1201	228	3	species	specie	NNS
cord-022561-rv5j1201	228	4	the	the	DT
cord-022561-rv5j1201	228	5	majority	majority	NN
cord-022561-rv5j1201	228	6	of	of	IN
cord-022561-rv5j1201	228	7	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	228	8	in	in	IN
cord-022561-rv5j1201	228	9	blood	blood	NN
cord-022561-rv5j1201	228	10	circulation	circulation	NN
cord-022561-rv5j1201	228	11	are	be	VBP
cord-022561-rv5j1201	228	12	T	t	NN
cord-022561-rv5j1201	228	13	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	228	14	.	.	.
cord-022561-rv5j1201	229	1	The	the	DT
cord-022561-rv5j1201	229	2	concentration	concentration	NN
cord-022561-rv5j1201	229	3	of	of	IN
cord-022561-rv5j1201	229	4	blood	blood	NN
cord-022561-rv5j1201	229	5	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	229	6	decreases	decrease	VBZ
cord-022561-rv5j1201	229	7	with	with	IN
cord-022561-rv5j1201	229	8	age	age	NN
cord-022561-rv5j1201	229	9	.	.	.
cord-022561-rv5j1201	230	1	Thrombopoiesis	Thrombopoiesis	NNP
cord-022561-rv5j1201	230	2	.	.	.
cord-022561-rv5j1201	231	1	Thrombopoiesis	thrombopoiesis	NN
cord-022561-rv5j1201	231	2	-	-	:
cord-022561-rv5j1201	231	3	from	from	IN
cord-022561-rv5j1201	231	4	thrombos	thrombos	NNP
cord-022561-rv5j1201	232	1	(	(	-LRB-
cord-022561-rv5j1201	232	2	Gr	Gr	NNP
cord-022561-rv5j1201	232	3	.	.	NNP
cord-022561-rv5j1201	232	4	,	,	,
cord-022561-rv5j1201	232	5	clot)refers	clot)refers	NNPS
cord-022561-rv5j1201	232	6	to	to	IN
cord-022561-rv5j1201	232	7	the	the	DT
cord-022561-rv5j1201	232	8	production	production	NN
cord-022561-rv5j1201	232	9	of	of	IN
cord-022561-rv5j1201	232	10	platelets	platelet	NNS
cord-022561-rv5j1201	232	11	,	,	,
cord-022561-rv5j1201	232	12	which	which	WDT
cord-022561-rv5j1201	232	13	are	be	VBP
cord-022561-rv5j1201	232	14	small	small	JJ
cord-022561-rv5j1201	232	15	(	(	-LRB-
cord-022561-rv5j1201	232	16	2	2	CD
cord-022561-rv5j1201	232	17	to	to	IN
cord-022561-rv5j1201	232	18	4	4	CD
cord-022561-rv5j1201	232	19	µm	µm	CD
cord-022561-rv5j1201	232	20	)	)	-RRB-
cord-022561-rv5j1201	232	21	,	,	,
cord-022561-rv5j1201	232	22	round	round	JJ
cord-022561-rv5j1201	232	23	to	to	IN
cord-022561-rv5j1201	232	24	ovoid	ovoid	JJ
cord-022561-rv5j1201	232	25	,	,	,
cord-022561-rv5j1201	232	26	anucleate	anucleate	NN
cord-022561-rv5j1201	232	27	cells	cell	NNS
cord-022561-rv5j1201	232	28	within	within	IN
cord-022561-rv5j1201	232	29	blood	blood	NN
cord-022561-rv5j1201	232	30	vessels	vessel	NNS
cord-022561-rv5j1201	232	31	.	.	.
cord-022561-rv5j1201	233	1	Platelets	platelet	NNS
cord-022561-rv5j1201	233	2	have	have	VBP
cord-022561-rv5j1201	233	3	a	a	DT
cord-022561-rv5j1201	233	4	central	central	JJ
cord-022561-rv5j1201	233	5	role	role	NN
cord-022561-rv5j1201	233	6	in	in	IN
cord-022561-rv5j1201	233	7	primary	primary	JJ
cord-022561-rv5j1201	233	8	hemostasis	hemostasis	NN
cord-022561-rv5j1201	233	9	but	but	CC
cord-022561-rv5j1201	233	10	also	also	RB
cord-022561-rv5j1201	233	11	participate	participate	VB
cord-022561-rv5j1201	233	12	in	in	IN
cord-022561-rv5j1201	233	13	secondary	secondary	JJ
cord-022561-rv5j1201	233	14	hemostasis	hemostasis	NN
cord-022561-rv5j1201	233	15	(	(	-LRB-
cord-022561-rv5j1201	233	16	coagulation	coagulation	NN
cord-022561-rv5j1201	233	17	)	)	-RRB-
cord-022561-rv5j1201	233	18	and	and	CC
cord-022561-rv5j1201	233	19	inflammatory	inflammatory	JJ
cord-022561-rv5j1201	233	20	pathways	pathway	NNS
cord-022561-rv5j1201	233	21	(	(	-LRB-
cord-022561-rv5j1201	233	22	see	see	VB
cord-022561-rv5j1201	233	23	Chapters	chapter	NNS
cord-022561-rv5j1201	233	24	2	2	CD
cord-022561-rv5j1201	233	25	and	and	CC
cord-022561-rv5j1201	233	26	3	3	CD
cord-022561-rv5j1201	233	27	)	)	-RRB-
cord-022561-rv5j1201	233	28	.	.	.
cord-022561-rv5j1201	234	1	Thrombopoietin	Thrombopoietin	NNP
cord-022561-rv5j1201	234	2	(	(	-LRB-
cord-022561-rv5j1201	234	3	Tpo	Tpo	NNP
cord-022561-rv5j1201	234	4	)	)	-RRB-
cord-022561-rv5j1201	234	5	is	be	VBZ
cord-022561-rv5j1201	234	6	the	the	DT
cord-022561-rv5j1201	234	7	primary	primary	JJ
cord-022561-rv5j1201	234	8	regulator	regulator	NN
cord-022561-rv5j1201	234	9	of	of	IN
cord-022561-rv5j1201	234	10	thrombopoiesis	thrombopoiesis	NNP
cord-022561-rv5j1201	234	11	.	.	.
cord-022561-rv5j1201	235	1	The	the	DT
cord-022561-rv5j1201	235	2	liver	liver	NN
cord-022561-rv5j1201	235	3	and	and	CC
cord-022561-rv5j1201	235	4	renal	renal	JJ
cord-022561-rv5j1201	235	5	tubular	tubular	JJ
cord-022561-rv5j1201	235	6	epithelial	epithelial	JJ
cord-022561-rv5j1201	235	7	cells	cell	NNS
cord-022561-rv5j1201	235	8	constantly	constantly	RB
cord-022561-rv5j1201	235	9	produce	produce	VBP
cord-022561-rv5j1201	235	10	Tpo	Tpo	NNP
cord-022561-rv5j1201	235	11	,	,	,
cord-022561-rv5j1201	235	12	which	which	WDT
cord-022561-rv5j1201	235	13	is	be	VBZ
cord-022561-rv5j1201	235	14	then	then	RB
cord-022561-rv5j1201	235	15	cleared	clear	VBN
cord-022561-rv5j1201	235	16	and	and	CC
cord-022561-rv5j1201	235	17	destroyed	destroy	VBN
cord-022561-rv5j1201	235	18	by	by	IN
cord-022561-rv5j1201	235	19	platelets	platelet	NNS
cord-022561-rv5j1201	235	20	and	and	CC
cord-022561-rv5j1201	235	21	their	-PRON-	PRP$
cord-022561-rv5j1201	235	22	precursors	precursor	NNS
cord-022561-rv5j1201	235	23	.	.	.
cord-022561-rv5j1201	236	1	Therefore	therefore	RB
cord-022561-rv5j1201	236	2	plasma	plasma	NN
cord-022561-rv5j1201	236	3	Tpo	Tpo	NNP
cord-022561-rv5j1201	236	4	concentration	concentration	NN
cord-022561-rv5j1201	236	5	is	be	VBZ
cord-022561-rv5j1201	236	6	inversely	inversely	RB
cord-022561-rv5j1201	236	7	proportional	proportional	JJ
cord-022561-rv5j1201	236	8	to	to	IN
cord-022561-rv5j1201	236	9	platelet	platelet	NN
cord-022561-rv5j1201	236	10	and	and	CC
cord-022561-rv5j1201	236	11	platelet	platelet	NN
cord-022561-rv5j1201	236	12	precursor	precursor	NN
cord-022561-rv5j1201	236	13	mass	mass	NN
cord-022561-rv5j1201	236	14	.	.	.
cord-022561-rv5j1201	237	1	If	if	IN
cord-022561-rv5j1201	237	2	the	the	DT
cord-022561-rv5j1201	237	3	platelet	platelet	NN
cord-022561-rv5j1201	237	4	mass	mass	NN
cord-022561-rv5j1201	237	5	is	be	VBZ
cord-022561-rv5j1201	237	6	decreased	decrease	VBN
cord-022561-rv5j1201	237	7	,	,	,
cord-022561-rv5j1201	237	8	less	less	JJR
cord-022561-rv5j1201	237	9	Tpo	Tpo	NNP
cord-022561-rv5j1201	237	10	is	be	VBZ
cord-022561-rv5j1201	237	11	cleared	clear	VBN
cord-022561-rv5j1201	237	12	,	,	,
cord-022561-rv5j1201	237	13	and	and	CC
cord-022561-rv5j1201	237	14	there	there	EX
cord-022561-rv5j1201	237	15	is	be	VBZ
cord-022561-rv5j1201	237	16	subsequently	subsequently	RB
cord-022561-rv5j1201	237	17	more	more	RBR
cord-022561-rv5j1201	237	18	free	free	JJ
cord-022561-rv5j1201	237	19	plasma	plasma	NN
cord-022561-rv5j1201	237	20	Tpo	Tpo	NNP
cord-022561-rv5j1201	237	21	to	to	TO
cord-022561-rv5j1201	237	22	stimulate	stimulate	VB
cord-022561-rv5j1201	237	23	thrombopoiesis	thrombopoiesis	NN
cord-022561-rv5j1201	237	24	.	.	.
cord-022561-rv5j1201	238	1	The	the	DT
cord-022561-rv5j1201	238	2	earliest	early	JJS
cord-022561-rv5j1201	238	3	morphologically	morphologically	RB
cord-022561-rv5j1201	238	4	identifiable	identifiable	JJ
cord-022561-rv5j1201	238	5	platelet	platelet	NN
cord-022561-rv5j1201	238	6	precursor	precursor	NN
cord-022561-rv5j1201	238	7	is	be	VBZ
cord-022561-rv5j1201	238	8	the	the	DT
cord-022561-rv5j1201	238	9	megakaryoblast	megakaryoblast	NN
cord-022561-rv5j1201	238	10	,	,	,
cord-022561-rv5j1201	238	11	which	which	WDT
cord-022561-rv5j1201	238	12	undergoes	undergo	VBZ
cord-022561-rv5j1201	238	13	nuclear	nuclear	JJ
cord-022561-rv5j1201	238	14	reduplications	reduplication	NNS
cord-022561-rv5j1201	238	15	without	without	IN
cord-022561-rv5j1201	238	16	cell	cell	NN
cord-022561-rv5j1201	238	17	division	division	NN
cord-022561-rv5j1201	238	18	,	,	,
cord-022561-rv5j1201	238	19	termed	term	VBN
cord-022561-rv5j1201	238	20	endomitosis	endomitosis	NN
cord-022561-rv5j1201	238	21	,	,	,
cord-022561-rv5j1201	238	22	to	to	TO
cord-022561-rv5j1201	238	23	form	form	VB
cord-022561-rv5j1201	238	24	a	a	DT
cord-022561-rv5j1201	238	25	megakaryocyte	megakaryocyte	NN
cord-022561-rv5j1201	238	26	with	with	IN
cord-022561-rv5j1201	238	27	8	8	CD
cord-022561-rv5j1201	238	28	to	to	TO
cord-022561-rv5j1201	238	29	64	64	CD
cord-022561-rv5j1201	238	30	nuclei	nucleus	NNS
cord-022561-rv5j1201	238	31	.	.	.
cord-022561-rv5j1201	239	1	As	as	IN
cord-022561-rv5j1201	239	2	the	the	DT
cord-022561-rv5j1201	239	3	name	name	NN
cord-022561-rv5j1201	239	4	suggests	suggest	VBZ
cord-022561-rv5j1201	239	5	,	,	,
cord-022561-rv5j1201	239	6	megakaryocytes	megakaryocytes	NNP
cord-022561-rv5j1201	239	7	are	be	VBP
cord-022561-rv5j1201	239	8	very	very	RB
cord-022561-rv5j1201	239	9	large	large	JJ
cord-022561-rv5j1201	239	10	cells	cell	NNS
cord-022561-rv5j1201	239	11	,	,	,
cord-022561-rv5j1201	239	12	much	much	RB
cord-022561-rv5j1201	239	13	larger	large	JJR
cord-022561-rv5j1201	239	14	than	than	IN
cord-022561-rv5j1201	239	15	any	any	DT
cord-022561-rv5j1201	239	16	other	other	JJ
cord-022561-rv5j1201	239	17	hematopoietic	hematopoietic	JJ
cord-022561-rv5j1201	239	18	cell	cell	NN
cord-022561-rv5j1201	239	19	;	;	:
cord-022561-rv5j1201	239	20	also	also	RB
cord-022561-rv5j1201	239	21	see	see	VB
cord-022561-rv5j1201	239	22	Fig	Fig	NNP
cord-022561-rv5j1201	239	23	.	.	.
cord-022561-rv5j1201	240	1	13	13	CD
cord-022561-rv5j1201	240	2	-1	-1	CD
cord-022561-rv5j1201	240	3	)	)	-RRB-
cord-022561-rv5j1201	240	4	.	.	.
cord-022561-rv5j1201	241	1	Megakaryocytes	megakaryocyte	NNS
cord-022561-rv5j1201	241	2	neighbor	neighbor	NN
cord-022561-rv5j1201	241	3	venous	venous	JJ
cord-022561-rv5j1201	241	4	sinusoids	sinusoid	NNS
cord-022561-rv5j1201	241	5	,	,	,
cord-022561-rv5j1201	241	6	extend	extend	VB
cord-022561-rv5j1201	241	7	their	-PRON-	PRP$
cord-022561-rv5j1201	241	8	cytoplasmic	cytoplasmic	JJ
cord-022561-rv5j1201	241	9	processes	process	NNS
cord-022561-rv5j1201	241	10	into	into	IN
cord-022561-rv5j1201	241	11	vascular	vascular	JJ
cord-022561-rv5j1201	241	12	lumens	lumen	NNS
cord-022561-rv5j1201	241	13	,	,	,
cord-022561-rv5j1201	241	14	and	and	CC
cord-022561-rv5j1201	241	15	shed	shed	VBD
cord-022561-rv5j1201	241	16	membranebound	membranebound	JJ
cord-022561-rv5j1201	241	17	cytoplasmic	cytoplasmic	JJ
cord-022561-rv5j1201	241	18	fragments	fragment	NNS
cord-022561-rv5j1201	241	19	(	(	-LRB-
cord-022561-rv5j1201	241	20	platelets	platelet	NNS
cord-022561-rv5j1201	241	21	)	)	-RRB-
cord-022561-rv5j1201	241	22	into	into	IN
cord-022561-rv5j1201	241	23	blood	blood	NN
cord-022561-rv5j1201	241	24	circulation	circulation	NN
cord-022561-rv5j1201	241	25	.	.	.
cord-022561-rv5j1201	242	1	Orderly	orderly	JJ
cord-022561-rv5j1201	242	2	platelet	platelet	NN
cord-022561-rv5j1201	242	3	shedding	shedding	NN
cord-022561-rv5j1201	242	4	is	be	VBZ
cord-022561-rv5j1201	242	5	partially	partially	RB
cord-022561-rv5j1201	242	6	facilitated	facilitate	VBN
cord-022561-rv5j1201	242	7	by	by	IN
cord-022561-rv5j1201	242	8	β	β	NN
cord-022561-rv5j1201	242	9	1	1	CD
cord-022561-rv5j1201	242	10	-tubulin	-tubulin	SYM
cord-022561-rv5j1201	242	11	microtubules	microtubule	NNS
cord-022561-rv5j1201	242	12	within	within	IN
cord-022561-rv5j1201	242	13	megakaryocytes	megakaryocyte	NNS
cord-022561-rv5j1201	242	14	.	.	.
cord-022561-rv5j1201	243	1	Platelets	platelet	NNS
cord-022561-rv5j1201	243	2	circulate	circulate	VBP
cord-022561-rv5j1201	243	3	in	in	IN
cord-022561-rv5j1201	243	4	a	a	DT
cord-022561-rv5j1201	243	5	quiescent	quiescent	JJ
cord-022561-rv5j1201	243	6	form	form	NN
cord-022561-rv5j1201	243	7	and	and	CC
cord-022561-rv5j1201	243	8	become	become	VBN
cord-022561-rv5j1201	243	9	activated	activate	VBN
cord-022561-rv5j1201	243	10	by	by	IN
cord-022561-rv5j1201	243	11	binding	bind	VBG
cord-022561-rv5j1201	243	12	platelet	platelet	NN
cord-022561-rv5j1201	243	13	agonists	agonist	NNS
cord-022561-rv5j1201	243	14	,	,	,
cord-022561-rv5j1201	243	15	including	include	VBG
cord-022561-rv5j1201	243	16	thrombin	thrombin	NN
cord-022561-rv5j1201	243	17	,	,	,
cord-022561-rv5j1201	243	18	adenosine	adenosine	NN
cord-022561-rv5j1201	243	19	diphosphate	diphosphate	NN
cord-022561-rv5j1201	243	20	(	(	-LRB-
cord-022561-rv5j1201	243	21	ADP	ADP	NNP
cord-022561-rv5j1201	243	22	)	)	-RRB-
cord-022561-rv5j1201	243	23	,	,	,
cord-022561-rv5j1201	243	24	and	and	CC
cord-022561-rv5j1201	243	25	thromboxane	thromboxane	NN
cord-022561-rv5j1201	243	26	.	.	.
cord-022561-rv5j1201	244	1	Platelet	platelet	NN
cord-022561-rv5j1201	244	2	activation	activation	NN
cord-022561-rv5j1201	244	3	causes	cause	VBZ
cord-022561-rv5j1201	244	4	shape	shape	NN
cord-022561-rv5j1201	244	5	change	change	NN
cord-022561-rv5j1201	244	6	,	,	,
cord-022561-rv5j1201	244	7	granule	granule	NN
cord-022561-rv5j1201	244	8	release	release	NN
cord-022561-rv5j1201	244	9	,	,	,
cord-022561-rv5j1201	244	10	and	and	CC
cord-022561-rv5j1201	244	11	relocation	relocation	NN
cord-022561-rv5j1201	244	12	of	of	IN
cord-022561-rv5j1201	244	13	procoagulant	procoagulant	JJ
cord-022561-rv5j1201	244	14	phospholipids	phospholipid	NNS
cord-022561-rv5j1201	244	15	and	and	CC
cord-022561-rv5j1201	244	16	glycoproteins	glycoprotein	NNS
cord-022561-rv5j1201	244	17	(	(	-LRB-
cord-022561-rv5j1201	244	18	GPs	GPs	NNP
cord-022561-rv5j1201	244	19	)	)	-RRB-
cord-022561-rv5j1201	244	20	to	to	IN
cord-022561-rv5j1201	244	21	the	the	DT
cord-022561-rv5j1201	244	22	outer	outer	JJ
cord-022561-rv5j1201	244	23	cell	cell	NN
cord-022561-rv5j1201	244	24	membrane	membrane	NN
cord-022561-rv5j1201	244	25	.	.	.
cord-022561-rv5j1201	245	1	Specific	specific	JJ
cord-022561-rv5j1201	245	2	procoagulant	procoagulant	JJ
cord-022561-rv5j1201	245	3	actions	action	NNS
cord-022561-rv5j1201	245	4	include	include	VBP
cord-022561-rv5j1201	245	5	release	release	NN
cord-022561-rv5j1201	245	6	of	of	IN
cord-022561-rv5j1201	245	7	calcium	calcium	NN
cord-022561-rv5j1201	245	8	,	,	,
cord-022561-rv5j1201	245	9	von	von	NNP
cord-022561-rv5j1201	245	10	Willebrand	Willebrand	NNP
cord-022561-rv5j1201	245	11	factor	factor	NN
cord-022561-rv5j1201	245	12	(	(	-LRB-
cord-022561-rv5j1201	245	13	vWF	vWF	NNP
cord-022561-rv5j1201	245	14	)	)	-RRB-
cord-022561-rv5j1201	245	15	,	,	,
cord-022561-rv5j1201	245	16	factor	factor	NN
cord-022561-rv5j1201	245	17	V	v	NN
cord-022561-rv5j1201	245	18	,	,	,
cord-022561-rv5j1201	245	19	and	and	CC
cord-022561-rv5j1201	245	20	fibrinogen	fibrinogen	NN
cord-022561-rv5j1201	245	21	,	,	,
cord-022561-rv5j1201	245	22	as	as	RB
cord-022561-rv5j1201	245	23	well	well	RB
cord-022561-rv5j1201	245	24	as	as	IN
cord-022561-rv5j1201	245	25	providing	provide	VBG
cord-022561-rv5j1201	245	26	phosphatidylserine	phosphatidylserine	NN
cord-022561-rv5j1201	245	27	-	-	HYPH
cord-022561-rv5j1201	245	28	rich	rich	JJ
cord-022561-rv5j1201	245	29	binding	binding	NN
cord-022561-rv5j1201	245	30	sites	site	NNS
cord-022561-rv5j1201	245	31	for	for	IN
cord-022561-rv5j1201	245	32	the	the	DT
cord-022561-rv5j1201	245	33	extrinsic	extrinsic	JJ
cord-022561-rv5j1201	245	34	tenase	tenase	NN
cord-022561-rv5j1201	245	35	(	(	-LRB-
cord-022561-rv5j1201	245	36	factors	factor	NNS
cord-022561-rv5j1201	245	37	III	III	NNP
cord-022561-rv5j1201	245	38	,	,	,
cord-022561-rv5j1201	245	39	VII	VII	NNP
cord-022561-rv5j1201	245	40	,	,	,
cord-022561-rv5j1201	245	41	and	and	CC
cord-022561-rv5j1201	245	42	X	X	NNP
cord-022561-rv5j1201	245	43	)	)	-RRB-
cord-022561-rv5j1201	245	44	,	,	,
cord-022561-rv5j1201	245	45	intrinsic	intrinsic	JJ
cord-022561-rv5j1201	245	46	tenase	tenase	NN
cord-022561-rv5j1201	245	47	(	(	-LRB-
cord-022561-rv5j1201	245	48	factors	factor	NNS
cord-022561-rv5j1201	245	49	IX	IX	NNP
cord-022561-rv5j1201	245	50	,	,	,
cord-022561-rv5j1201	245	51	VIII	VIII	NNP
cord-022561-rv5j1201	245	52	,	,	,
cord-022561-rv5j1201	245	53	and	and	CC
cord-022561-rv5j1201	245	54	X	X	NNP
cord-022561-rv5j1201	245	55	)	)	-RRB-
cord-022561-rv5j1201	245	56	,	,	,
cord-022561-rv5j1201	245	57	and	and	CC
cord-022561-rv5j1201	245	58	prothrombinase	prothrombinase	NNP
cord-022561-rv5j1201	245	59	(	(	-LRB-
cord-022561-rv5j1201	245	60	factors	factor	NNS
cord-022561-rv5j1201	245	61	X	X	NNP
cord-022561-rv5j1201	245	62	,	,	,
cord-022561-rv5j1201	245	63	V	v	NN
cord-022561-rv5j1201	245	64	,	,	,
cord-022561-rv5j1201	245	65	and	and	CC
cord-022561-rv5j1201	245	66	II	II	NNP
cord-022561-rv5j1201	245	67	)	)	-RRB-
cord-022561-rv5j1201	245	68	coagulation	coagulation	NN
cord-022561-rv5j1201	245	69	complexes	complex	NNS
cord-022561-rv5j1201	245	70	.	.	.
cord-022561-rv5j1201	246	1	Platelet	platelet	NN
cord-022561-rv5j1201	246	2	GP	gp	NN
cord-022561-rv5j1201	246	3	surface	surface	NN
cord-022561-rv5j1201	246	4	receptors	receptor	NNS
cord-022561-rv5j1201	246	5	include	include	VBP
cord-022561-rv5j1201	246	6	those	those	DT
cord-022561-rv5j1201	246	7	for	for	IN
cord-022561-rv5j1201	246	8	binding	bind	VBG
cord-022561-rv5j1201	246	9	vWF	vwf	XX
cord-022561-rv5j1201	247	1	(	(	-LRB-
cord-022561-rv5j1201	247	2	GPIb	GPIb	NNP
cord-022561-rv5j1201	247	3	-	-	HYPH
cord-022561-rv5j1201	247	4	IX	IX	NNP
cord-022561-rv5j1201	247	5	-	-	HYPH
cord-022561-rv5j1201	247	6	V	V	NNP
cord-022561-rv5j1201	247	7	)	)	-RRB-
cord-022561-rv5j1201	247	8	,	,	,
cord-022561-rv5j1201	247	9	collagen	collagen	NNP
cord-022561-rv5j1201	247	10	(	(	-LRB-
cord-022561-rv5j1201	247	11	GPVI	GPVI	NNP
cord-022561-rv5j1201	247	12	)	)	-RRB-
cord-022561-rv5j1201	247	13	,	,	,
cord-022561-rv5j1201	247	14	and	and	CC
cord-022561-rv5j1201	247	15	fibrinogen	fibrinogen	NN
cord-022561-rv5j1201	247	16	(	(	-LRB-
cord-022561-rv5j1201	247	17	GPIIb	GPIIb	NNP
cord-022561-rv5j1201	247	18	-	-	HYPH
cord-022561-rv5j1201	247	19	IIIa	IIIa	NNP
cord-022561-rv5j1201	247	20	)	)	-RRB-
cord-022561-rv5j1201	247	21	,	,	,
cord-022561-rv5j1201	247	22	which	which	WDT
cord-022561-rv5j1201	247	23	facilitate	facilitate	VBP
cord-022561-rv5j1201	247	24	 	 	_SP
cord-022561-rv5j1201	247	25	Increased	increase	VBN
cord-022561-rv5j1201	247	26	destruction	destruction	NN
cord-022561-rv5j1201	247	27	Hemorrhage	hemorrhage	NN
cord-022561-rv5j1201	247	28	(	(	-LRB-
cord-022561-rv5j1201	247	29	especially	especially	RB
cord-022561-rv5j1201	247	30	erythrocytes	erythrocyte	NNS
cord-022561-rv5j1201	247	31	)	)	-RRB-
cord-022561-rv5j1201	248	1	Consumption	consumption	NN
cord-022561-rv5j1201	248	2	(	(	-LRB-
cord-022561-rv5j1201	248	3	platelets	platelet	NNS
cord-022561-rv5j1201	248	4	)	)	-RRB-
cord-022561-rv5j1201	248	5	Neoplasia	neoplasia	NN
cord-022561-rv5j1201	248	6	Altered	alter	VBN
cord-022561-rv5j1201	248	7	distribution	distribution	NN
cord-022561-rv5j1201	248	8	Abnormal	abnormal	JJ
cord-022561-rv5j1201	248	9	function	function	NN
cord-022561-rv5j1201	248	10	Bone	bone	NN
cord-022561-rv5j1201	248	11	marrow	marrow	NN
cord-022561-rv5j1201	248	12	is	be	VBZ
cord-022561-rv5j1201	248	13	not	not	RB
cord-022561-rv5j1201	248	14	routinely	routinely	RB
cord-022561-rv5j1201	248	15	sampled	sample	VBN
cord-022561-rv5j1201	248	16	during	during	IN
cord-022561-rv5j1201	248	17	postmortem	postmortem	JJ
cord-022561-rv5j1201	248	18	examinations	examination	NNS
cord-022561-rv5j1201	248	19	.	.	.
cord-022561-rv5j1201	249	1	However	however	RB
cord-022561-rv5j1201	249	2	,	,	,
cord-022561-rv5j1201	249	3	indications	indication	NNS
cord-022561-rv5j1201	249	4	for	for	IN
cord-022561-rv5j1201	249	5	bone	bone	NN
cord-022561-rv5j1201	249	6	marrow	marrow	NN
cord-022561-rv5j1201	249	7	evaluation	evaluation	NN
cord-022561-rv5j1201	249	8	include	include	VBP
cord-022561-rv5j1201	249	9	suspected	suspect	VBN
cord-022561-rv5j1201	249	10	leukemia	leukemia	NN
cord-022561-rv5j1201	249	11	,	,	,
cord-022561-rv5j1201	249	12	metastatic	metastatic	JJ
cord-022561-rv5j1201	249	13	neoplasia	neoplasia	NN
cord-022561-rv5j1201	249	14	within	within	IN
cord-022561-rv5j1201	249	15	bone	bone	NN
cord-022561-rv5j1201	249	16	marrow	marrow	NN
cord-022561-rv5j1201	249	17	,	,	,
cord-022561-rv5j1201	249	18	or	or	CC
cord-022561-rv5j1201	249	19	infectious	infectious	JJ
cord-022561-rv5j1201	249	20	myelitis	myelitis	NN
cord-022561-rv5j1201	249	21	,	,	,
cord-022561-rv5j1201	249	22	as	as	RB
cord-022561-rv5j1201	249	23	well	well	RB
cord-022561-rv5j1201	249	24	as	as	IN
cord-022561-rv5j1201	249	25	cytopenia(s	cytopenia(s	NNP
cord-022561-rv5j1201	249	26	)	)	-RRB-
cord-022561-rv5j1201	249	27	or	or	CC
cord-022561-rv5j1201	249	28	hematopoietic	hematopoietic	JJ
cord-022561-rv5j1201	249	29	dysplasia	dysplasia	NN
cord-022561-rv5j1201	249	30	of	of	IN
cord-022561-rv5j1201	249	31	unknown	unknown	JJ
cord-022561-rv5j1201	249	32	cause	cause	NN
cord-022561-rv5j1201	249	33	.	.	.
cord-022561-rv5j1201	250	1	Multimodal	Multimodal	NNP
cord-022561-rv5j1201	250	2	evaluation	evaluation	NN
cord-022561-rv5j1201	250	3	is	be	VBZ
cord-022561-rv5j1201	250	4	ideal	ideal	JJ
cord-022561-rv5j1201	250	5	,	,	,
cord-022561-rv5j1201	250	6	including	include	VBG
cord-022561-rv5j1201	250	7	a	a	DT
cord-022561-rv5j1201	250	8	recent	recent	JJ
cord-022561-rv5j1201	250	9	(	(	-LRB-
cord-022561-rv5j1201	250	10	<	<	NNP
cord-022561-rv5j1201	250	11	24	24	CD
cord-022561-rv5j1201	250	12	hours	hour	NNS
cord-022561-rv5j1201	250	13	)	)	-RRB-
cord-022561-rv5j1201	250	14	complete	complete	JJ
cord-022561-rv5j1201	250	15	blood	blood	NN
cord-022561-rv5j1201	250	16	count	count	NN
cord-022561-rv5j1201	250	17	with	with	IN
cord-022561-rv5j1201	250	18	bone	bone	NN
cord-022561-rv5j1201	250	19	marrow	marrow	NN
cord-022561-rv5j1201	250	20	cytologic	cytologic	JJ
cord-022561-rv5j1201	250	21	and	and	CC
cord-022561-rv5j1201	250	22	histopathologic	histopathologic	JJ
cord-022561-rv5j1201	250	23	examination	examination	NN
cord-022561-rv5j1201	250	24	.	.	.
cord-022561-rv5j1201	251	1	However	however	RB
cord-022561-rv5j1201	251	2	,	,	,
cord-022561-rv5j1201	251	3	antemortem	antemortem	NNP
cord-022561-rv5j1201	251	4	blood	blood	NN
cord-022561-rv5j1201	251	5	analyses	analysis	NNS
cord-022561-rv5j1201	251	6	are	be	VBP
cord-022561-rv5j1201	251	7	not	not	RB
cord-022561-rv5j1201	251	8	always	always	RB
cord-022561-rv5j1201	251	9	available	available	JJ
cord-022561-rv5j1201	251	10	,	,	,
cord-022561-rv5j1201	251	11	and	and	CC
cord-022561-rv5j1201	251	12	interpretation	interpretation	NN
cord-022561-rv5j1201	251	13	of	of	IN
cord-022561-rv5j1201	251	14	hematopoietic	hematopoietic	JJ
cord-022561-rv5j1201	251	15	cytomorphologic	cytomorphologic	JJ
cord-022561-rv5j1201	251	16	examination	examination	NN
cord-022561-rv5j1201	251	17	results	result	NNS
cord-022561-rv5j1201	251	18	becomes	become	VBZ
cord-022561-rv5j1201	251	19	difficult	difficult	JJ
cord-022561-rv5j1201	251	20	to	to	TO
cord-022561-rv5j1201	251	21	impossible	impossible	JJ
cord-022561-rv5j1201	251	22	shortly	shortly	RB
cord-022561-rv5j1201	251	23	after	after	IN
cord-022561-rv5j1201	251	24	death	death	NN
cord-022561-rv5j1201	251	25	.	.	.
cord-022561-rv5j1201	252	1	Postmortem	postmortem	JJ
cord-022561-rv5j1201	252	2	bone	bone	NN
cord-022561-rv5j1201	252	3	marrow	marrow	NN
cord-022561-rv5j1201	252	4	should	should	MD
cord-022561-rv5j1201	252	5	be	be	VB
cord-022561-rv5j1201	252	6	collected	collect	VBN
cord-022561-rv5j1201	252	7	as	as	RB
cord-022561-rv5j1201	252	8	soon	soon	RB
cord-022561-rv5j1201	252	9	as	as	IN
cord-022561-rv5j1201	252	10	possible	possible	JJ
cord-022561-rv5j1201	252	11	after	after	IN
cord-022561-rv5j1201	252	12	death	death	NN
cord-022561-rv5j1201	252	13	or	or	CC
cord-022561-rv5j1201	252	14	euthanasia	euthanasia	NN
cord-022561-rv5j1201	252	15	,	,	,
cord-022561-rv5j1201	252	16	preferably	preferably	RB
cord-022561-rv5j1201	252	17	within	within	IN
cord-022561-rv5j1201	252	18	30	30	CD
cord-022561-rv5j1201	252	19	minutes	minute	NNS
cord-022561-rv5j1201	252	20	.	.	.
cord-022561-rv5j1201	253	1	Samples	sample	NNS
cord-022561-rv5j1201	253	2	may	may	MD
cord-022561-rv5j1201	253	3	be	be	VB
cord-022561-rv5j1201	253	4	collected	collect	VBN
cord-022561-rv5j1201	253	5	from	from	IN
cord-022561-rv5j1201	253	6	the	the	DT
cord-022561-rv5j1201	253	7	proximal	proximal	JJ
cord-022561-rv5j1201	253	8	femur	femur	NN
cord-022561-rv5j1201	253	9	,	,	,
cord-022561-rv5j1201	253	10	rib	rib	NN
cord-022561-rv5j1201	253	11	,	,	,
cord-022561-rv5j1201	253	12	sternum	sternum	NN
cord-022561-rv5j1201	253	13	or	or	CC
cord-022561-rv5j1201	253	14	vertebrae	vertebrae	NN
cord-022561-rv5j1201	253	15	.	.	.
cord-022561-rv5j1201	254	1	When	when	WRB
cord-022561-rv5j1201	254	2	collecting	collect	VBG
cord-022561-rv5j1201	254	3	from	from	IN
cord-022561-rv5j1201	254	4	the	the	DT
cord-022561-rv5j1201	254	5	femur	femur	NN
cord-022561-rv5j1201	254	6	,	,	,
cord-022561-rv5j1201	254	7	the	the	DT
cord-022561-rv5j1201	254	8	femoral	femoral	JJ
cord-022561-rv5j1201	254	9	neck	neck	NN
cord-022561-rv5j1201	254	10	is	be	VBZ
cord-022561-rv5j1201	254	11	removed	remove	VBN
cord-022561-rv5j1201	254	12	with	with	IN
cord-022561-rv5j1201	254	13	a	a	DT
cord-022561-rv5j1201	254	14	bone	bone	NN
cord-022561-rv5j1201	254	15	saw	saw	NN
cord-022561-rv5j1201	254	16	,	,	,
cord-022561-rv5j1201	254	17	or	or	CC
cord-022561-rv5j1201	254	18	a	a	DT
cord-022561-rv5j1201	254	19	fragment	fragment	NN
cord-022561-rv5j1201	254	20	of	of	IN
cord-022561-rv5j1201	254	21	the	the	DT
cord-022561-rv5j1201	254	22	shaft	shaft	NN
cord-022561-rv5j1201	254	23	is	be	VBZ
cord-022561-rv5j1201	254	24	removed	remove	VBN
cord-022561-rv5j1201	254	25	with	with	IN
cord-022561-rv5j1201	254	26	bone	bone	NN
cord-022561-rv5j1201	254	27	-	-	HYPH
cord-022561-rv5j1201	254	28	cutting	cut	VBG
cord-022561-rv5j1201	254	29	shears	shear	NNS
cord-022561-rv5j1201	254	30	.	.	.
cord-022561-rv5j1201	255	1	Cytologic	cytologic	JJ
cord-022561-rv5j1201	255	2	samples	sample	NNS
cord-022561-rv5j1201	255	3	are	be	VBP
cord-022561-rv5j1201	255	4	first	first	RB
cord-022561-rv5j1201	255	5	collected	collect	VBN
cord-022561-rv5j1201	255	6	using	use	VBG
cord-022561-rv5j1201	255	7	the	the	DT
cord-022561-rv5j1201	255	8	paintbrush	paintbrush	NN
cord-022561-rv5j1201	255	9	technique	technique	NN
cord-022561-rv5j1201	255	10	:	:	:
cord-022561-rv5j1201	255	11	gently	gently	RB
cord-022561-rv5j1201	255	12	sample	sample	VB
cord-022561-rv5j1201	255	13	the	the	DT
cord-022561-rv5j1201	255	14	red	red	JJ
cord-022561-rv5j1201	255	15	marrow	marrow	NN
cord-022561-rv5j1201	255	16	with	with	IN
cord-022561-rv5j1201	255	17	a	a	DT
cord-022561-rv5j1201	255	18	clean	clean	JJ
cord-022561-rv5j1201	255	19	,	,	,
cord-022561-rv5j1201	255	20	dry	dry	JJ
cord-022561-rv5j1201	255	21	,	,	,
cord-022561-rv5j1201	255	22	naturalbristle	naturalbristle	NNP
cord-022561-rv5j1201	255	23	brush	brush	NN
cord-022561-rv5j1201	255	24	,	,	,
cord-022561-rv5j1201	255	25	and	and	CC
cord-022561-rv5j1201	255	26	then	then	RB
cord-022561-rv5j1201	255	27	carefully	carefully	RB
cord-022561-rv5j1201	255	28	brush	brush	VB
cord-022561-rv5j1201	255	29	the	the	DT
cord-022561-rv5j1201	255	30	material	material	NN
cord-022561-rv5j1201	255	31	onto	onto	IN
cord-022561-rv5j1201	255	32	a	a	DT
cord-022561-rv5j1201	255	33	clean	clean	JJ
cord-022561-rv5j1201	255	34	glass	glass	NN
cord-022561-rv5j1201	255	35	microscope	microscope	NN
cord-022561-rv5j1201	255	36	slide	slide	NN
cord-022561-rv5j1201	255	37	in	in	IN
cord-022561-rv5j1201	255	38	two	two	CD
cord-022561-rv5j1201	255	39	to	to	TO
cord-022561-rv5j1201	255	40	four	four	CD
cord-022561-rv5j1201	255	41	parallel	parallel	JJ
cord-022561-rv5j1201	255	42	wavy	wavy	JJ
cord-022561-rv5j1201	255	43	lines	line	NNS
cord-022561-rv5j1201	255	44	.	.	.
cord-022561-rv5j1201	256	1	The	the	DT
cord-022561-rv5j1201	256	2	brush	brush	NN
cord-022561-rv5j1201	256	3	should	should	MD
cord-022561-rv5j1201	256	4	be	be	VB
cord-022561-rv5j1201	256	5	cleaned	clean	VBN
cord-022561-rv5j1201	256	6	and	and	CC
cord-022561-rv5j1201	256	7	dried	dry	VBN
cord-022561-rv5j1201	256	8	before	before	IN
cord-022561-rv5j1201	256	9	its	-PRON-	PRP$
cord-022561-rv5j1201	256	10	use	use	NN
cord-022561-rv5j1201	256	11	on	on	IN
cord-022561-rv5j1201	256	12	a	a	DT
cord-022561-rv5j1201	256	13	different	different	JJ
cord-022561-rv5j1201	256	14	animal	animal	NN
cord-022561-rv5j1201	256	15	.	.	.
cord-022561-rv5j1201	257	1	The	the	DT
cord-022561-rv5j1201	257	2	slide	slide	NN
cord-022561-rv5j1201	257	3	is	be	VBZ
cord-022561-rv5j1201	257	4	then	then	RB
cord-022561-rv5j1201	257	5	air	air	NN
cord-022561-rv5j1201	257	6	dried	dry	VBN
cord-022561-rv5j1201	257	7	,	,	,
cord-022561-rv5j1201	257	8	stored	store	VBN
cord-022561-rv5j1201	257	9	away	away	RB
cord-022561-rv5j1201	257	10	from	from	IN
cord-022561-rv5j1201	257	11	formalin	formalin	NN
cord-022561-rv5j1201	257	12	fumes	fume	NNS
cord-022561-rv5j1201	257	13	,	,	,
cord-022561-rv5j1201	257	14	and	and	CC
cord-022561-rv5j1201	257	15	then	then	RB
cord-022561-rv5j1201	257	16	stained	stain	VBN
cord-022561-rv5j1201	257	17	with	with	IN
cord-022561-rv5j1201	257	18	a	a	DT
cord-022561-rv5j1201	257	19	routine	routine	NN
cord-022561-rv5j1201	257	20	(	(	-LRB-
cord-022561-rv5j1201	257	21	Romanowsky	Romanowsky	NNP
cord-022561-rv5j1201	257	22	)	)	-RRB-
cord-022561-rv5j1201	257	23	stain	stain	NN
cord-022561-rv5j1201	257	24	.	.	.
cord-022561-rv5j1201	258	1	For	for	IN
cord-022561-rv5j1201	258	2	histologic	histologic	JJ
cord-022561-rv5j1201	258	3	evaluation	evaluation	NN
cord-022561-rv5j1201	258	4	the	the	DT
cord-022561-rv5j1201	258	5	entire	entire	JJ
cord-022561-rv5j1201	258	6	femoral	femoral	JJ
cord-022561-rv5j1201	258	7	head	head	NN
cord-022561-rv5j1201	258	8	or	or	CC
cord-022561-rv5j1201	258	9	femoral	femoral	JJ
cord-022561-rv5j1201	258	10	shaft	shaft	NN
cord-022561-rv5j1201	258	11	or	or	CC
cord-022561-rv5j1201	258	12	rib	rib	NN
cord-022561-rv5j1201	258	13	fragment	fragment	NN
cord-022561-rv5j1201	258	14	with	with	IN
cord-022561-rv5j1201	258	15	exposed	expose	VBN
cord-022561-rv5j1201	258	16	red	red	JJ
cord-022561-rv5j1201	258	17	marrow	marrow	NN
cord-022561-rv5j1201	258	18	is	be	VBZ
cord-022561-rv5j1201	258	19	submersed	submerse	VBN
cord-022561-rv5j1201	258	20	in	in	IN
cord-022561-rv5j1201	258	21	10	10	CD
cord-022561-rv5j1201	258	22	%	%	NN
cord-022561-rv5j1201	258	23	neutral	neutral	JJ
cord-022561-rv5j1201	258	24	buffered	buffer	VBN
cord-022561-rv5j1201	258	25	formalin	formalin	NN
cord-022561-rv5j1201	258	26	.	.	.
cord-022561-rv5j1201	259	1	For	for	IN
cord-022561-rv5j1201	259	2	cosmetic	cosmetic	JJ
cord-022561-rv5j1201	259	3	necropsies	necropsy	NNS
cord-022561-rv5j1201	259	4	,	,	,
cord-022561-rv5j1201	259	5	samples	sample	NNS
cord-022561-rv5j1201	259	6	may	may	MD
cord-022561-rv5j1201	259	7	be	be	VB
cord-022561-rv5j1201	259	8	obtained	obtain	VBN
cord-022561-rv5j1201	259	9	by	by	IN
cord-022561-rv5j1201	259	10	antemortem	antemortem	NN
cord-022561-rv5j1201	259	11	techniques	technique	NNS
cord-022561-rv5j1201	259	12	,	,	,
cord-022561-rv5j1201	259	13	such	such	JJ
cord-022561-rv5j1201	259	14	as	as	IN
cord-022561-rv5j1201	259	15	needle	needle	NN
cord-022561-rv5j1201	259	16	biopsies	biopsy	NNS
cord-022561-rv5j1201	259	17	for	for	IN
cord-022561-rv5j1201	259	18	cytologic	cytologic	JJ
cord-022561-rv5j1201	259	19	examination	examination	NN
cord-022561-rv5j1201	259	20	and	and	CC
cord-022561-rv5j1201	259	21	core	core	NN
cord-022561-rv5j1201	259	22	biopsies	biopsy	NNS
cord-022561-rv5j1201	259	23	for	for	IN
cord-022561-rv5j1201	259	24	histopathologic	histopathologic	JJ
cord-022561-rv5j1201	259	25	examination	examination	NN
cord-022561-rv5j1201	259	26	.	.	.
cord-022561-rv5j1201	260	1	The	the	DT
cord-022561-rv5j1201	260	2	complete	complete	JJ
cord-022561-rv5j1201	260	3	blood	blood	NN
cord-022561-rv5j1201	260	4	count	count	NN
cord-022561-rv5j1201	260	5	(	(	-LRB-
cord-022561-rv5j1201	260	6	CBC	CBC	NNP
cord-022561-rv5j1201	260	7	)	)	-RRB-
cord-022561-rv5j1201	260	8	is	be	VBZ
cord-022561-rv5j1201	260	9	the	the	DT
cord-022561-rv5j1201	260	10	cornerstone	cornerstone	NN
cord-022561-rv5j1201	260	11	for	for	IN
cord-022561-rv5j1201	260	12	diagnosis	diagnosis	NN
cord-022561-rv5j1201	260	13	of	of	IN
cord-022561-rv5j1201	260	14	hematologic	hematologic	JJ
cord-022561-rv5j1201	260	15	disturbances	disturbance	NNS
cord-022561-rv5j1201	260	16	and	and	CC
cord-022561-rv5j1201	260	17	is	be	VBZ
cord-022561-rv5j1201	260	18	often	often	RB
cord-022561-rv5j1201	260	19	part	part	NN
cord-022561-rv5j1201	260	20	of	of	IN
cord-022561-rv5j1201	260	21	a	a	DT
cord-022561-rv5j1201	260	22	minimum	minimum	JJ
cord-022561-rv5j1201	260	23	database	database	NN
cord-022561-rv5j1201	260	24	in	in	IN
cord-022561-rv5j1201	260	25	sick	sick	JJ
cord-022561-rv5j1201	260	26	patients	patient	NNS
cord-022561-rv5j1201	260	27	.	.	.
cord-022561-rv5j1201	261	1	The	the	DT
cord-022561-rv5j1201	261	2	CBC	CBC	NNP
cord-022561-rv5j1201	261	3	includes	include	VBZ
cord-022561-rv5j1201	261	4	numeric	numeric	JJ
cord-022561-rv5j1201	261	5	data	datum	NNS
cord-022561-rv5j1201	261	6	indicating	indicate	VBG
cord-022561-rv5j1201	261	7	the	the	DT
cord-022561-rv5j1201	261	8	concentration	concentration	NN
cord-022561-rv5j1201	261	9	of	of	IN
cord-022561-rv5j1201	261	10	different	different	JJ
cord-022561-rv5j1201	261	11	cell	cell	NN
cord-022561-rv5j1201	261	12	types	type	NNS
cord-022561-rv5j1201	261	13	,	,	,
cord-022561-rv5j1201	261	14	as	as	RB
cord-022561-rv5j1201	261	15	well	well	RB
cord-022561-rv5j1201	261	16	as	as	IN
cord-022561-rv5j1201	261	17	other	other	JJ
cord-022561-rv5j1201	261	18	estimations	estimation	NNS
cord-022561-rv5j1201	261	19	of	of	IN
cord-022561-rv5j1201	261	20	red	red	JJ
cord-022561-rv5j1201	261	21	blood	blood	NN
cord-022561-rv5j1201	261	22	cell	cell	NN
cord-022561-rv5j1201	261	23	mass	mass	NN
cord-022561-rv5j1201	261	24	(	(	-LRB-
cord-022561-rv5j1201	261	25	hemoglobin	hemoglobin	NN
cord-022561-rv5j1201	261	26	concentration	concentration	NN
cord-022561-rv5j1201	261	27	,	,	,
cord-022561-rv5j1201	261	28	packed	pack	VBN
cord-022561-rv5j1201	261	29	-	-	HYPH
cord-022561-rv5j1201	261	30	cell	cell	NN
cord-022561-rv5j1201	261	31	volume	volume	NN
cord-022561-rv5j1201	261	32	,	,	,
cord-022561-rv5j1201	261	33	and	and	CC
cord-022561-rv5j1201	261	34	hematocrit	hematocrit	NN
cord-022561-rv5j1201	261	35	)	)	-RRB-
cord-022561-rv5j1201	261	36	,	,	,
cord-022561-rv5j1201	261	37	red	red	JJ
cord-022561-rv5j1201	261	38	blood	blood	NN
cord-022561-rv5j1201	261	39	cell	cell	NN
cord-022561-rv5j1201	261	40	volume	volume	NN
cord-022561-rv5j1201	261	41	(	(	-LRB-
cord-022561-rv5j1201	261	42	mean	mean	JJ
cord-022561-rv5j1201	261	43	cell	cell	NN
cord-022561-rv5j1201	261	44	volume	volume	NN
cord-022561-rv5j1201	261	45	)	)	-RRB-
cord-022561-rv5j1201	261	46	,	,	,
cord-022561-rv5j1201	261	47	and	and	CC
cord-022561-rv5j1201	261	48	red	red	JJ
cord-022561-rv5j1201	261	49	blood	blood	NN
cord-022561-rv5j1201	261	50	cell	cell	NN
cord-022561-rv5j1201	261	51	hemoglobin	hemoglobin	NN
cord-022561-rv5j1201	261	52	content	content	NN
cord-022561-rv5j1201	261	53	(	(	-LRB-
cord-022561-rv5j1201	261	54	mean	mean	VB
cord-022561-rv5j1201	261	55	cell	cell	NN
cord-022561-rv5j1201	261	56	hemoglobin	hemoglobin	NN
cord-022561-rv5j1201	261	57	and	and	CC
cord-022561-rv5j1201	261	58	mean	mean	VB
cord-022561-rv5j1201	261	59	cell	cell	NN
cord-022561-rv5j1201	261	60	hemoglobin	hemoglobin	NN
cord-022561-rv5j1201	261	61	concentration	concentration	NN
cord-022561-rv5j1201	261	62	)	)	-RRB-
cord-022561-rv5j1201	261	63	.	.	.
cord-022561-rv5j1201	262	1	Cell	cell	NN
cord-022561-rv5j1201	262	2	morphologic	morphologic	JJ
cord-022561-rv5j1201	262	3	features	feature	NNS
cord-022561-rv5j1201	262	4	and	and	CC
cord-022561-rv5j1201	262	5	the	the	DT
cord-022561-rv5j1201	262	6	presence	presence	NN
cord-022561-rv5j1201	262	7	or	or	CC
cord-022561-rv5j1201	262	8	absence	absence	NN
cord-022561-rv5j1201	262	9	of	of	IN
cord-022561-rv5j1201	262	10	hemic	hemic	JJ
cord-022561-rv5j1201	262	11	parasites	parasite	NNS
cord-022561-rv5j1201	262	12	are	be	VBP
cord-022561-rv5j1201	262	13	assessed	assess	VBN
cord-022561-rv5j1201	262	14	upon	upon	IN
cord-022561-rv5j1201	262	15	microscopic	microscopic	JJ
cord-022561-rv5j1201	262	16	review	review	NN
cord-022561-rv5j1201	262	17	of	of	IN
cord-022561-rv5j1201	262	18	a	a	DT
cord-022561-rv5j1201	262	19	blood	blood	NN
cord-022561-rv5j1201	262	20	smear	smear	NN
cord-022561-rv5j1201	262	21	and	and	CC
cord-022561-rv5j1201	262	22	are	be	VBP
cord-022561-rv5j1201	262	23	also	also	RB
cord-022561-rv5j1201	262	24	included	include	VBN
cord-022561-rv5j1201	262	25	in	in	IN
cord-022561-rv5j1201	262	26	a	a	DT
cord-022561-rv5j1201	262	27	CBC	CBC	NNP
cord-022561-rv5j1201	262	28	report	report	NN
cord-022561-rv5j1201	262	29	.	.	.
cord-022561-rv5j1201	263	1	(	(	-LRB-
cord-022561-rv5j1201	263	2	note	note	NN
cord-022561-rv5j1201	263	3	:	:	:
cord-022561-rv5j1201	263	4	Some	some	DT
cord-022561-rv5j1201	263	5	parasites	parasite	NNS
cord-022561-rv5j1201	263	6	may	may	MD
cord-022561-rv5j1201	263	7	infect	infect	VB
cord-022561-rv5j1201	263	8	blood	blood	NN
cord-022561-rv5j1201	263	9	cells	cell	NNS
cord-022561-rv5j1201	263	10	,	,	,
cord-022561-rv5j1201	263	11	such	such	JJ
cord-022561-rv5j1201	263	12	as	as	IN
cord-022561-rv5j1201	263	13	Hepatozoon	Hepatozoon	NNP
cord-022561-rv5j1201	263	14	organisms	organism	NNS
cord-022561-rv5j1201	263	15	within	within	IN
cord-022561-rv5j1201	263	16	circulating	circulate	VBG
cord-022561-rv5j1201	263	17	neutrophils	neutrophil	NNS
cord-022561-rv5j1201	263	18	or	or	CC
cord-022561-rv5j1201	263	19	monocytes	monocyte	NNS
cord-022561-rv5j1201	263	20	or	or	CC
cord-022561-rv5j1201	263	21	Bartonella	Bartonella	NNP
cord-022561-rv5j1201	263	22	organisms	organism	NNS
cord-022561-rv5j1201	263	23	within	within	IN
cord-022561-rv5j1201	263	24	erythrocytes	erythrocyte	NNS
cord-022561-rv5j1201	263	25	,	,	,
cord-022561-rv5j1201	263	26	but	but	CC
cord-022561-rv5j1201	263	27	mainly	mainly	RB
cord-022561-rv5j1201	263	28	cause	cause	VB
cord-022561-rv5j1201	263	29	disease	disease	NN
cord-022561-rv5j1201	263	30	in	in	IN
cord-022561-rv5j1201	263	31	other	other	JJ
cord-022561-rv5j1201	263	32	body	body	NN
cord-022561-rv5j1201	263	33	systems	system	NNS
cord-022561-rv5j1201	263	34	and	and	CC
cord-022561-rv5j1201	263	35	are	be	VBP
cord-022561-rv5j1201	263	36	therefore	therefore	RB
cord-022561-rv5j1201	263	37	not	not	RB
cord-022561-rv5j1201	263	38	discussed	discuss	VBN
cord-022561-rv5j1201	263	39	in	in	IN
cord-022561-rv5j1201	263	40	this	this	DT
cord-022561-rv5j1201	263	41	chapter	chapter	NN
cord-022561-rv5j1201	263	42	.	.	.
cord-022561-rv5j1201	263	43	)	)	-RRB-
cord-022561-rv5j1201	264	1	Learning	learn	VBG
cord-022561-rv5j1201	264	2	to	to	TO
cord-022561-rv5j1201	264	3	evaluate	evaluate	VB
cord-022561-rv5j1201	264	4	blood	blood	NN
cord-022561-rv5j1201	264	5	smears	smear	NNS
cord-022561-rv5j1201	264	6	is	be	VBZ
cord-022561-rv5j1201	264	7	a	a	DT
cord-022561-rv5j1201	264	8	valuable	valuable	JJ
cord-022561-rv5j1201	264	9	skill	skill	NN
cord-022561-rv5j1201	264	10	for	for	IN
cord-022561-rv5j1201	264	11	any	any	DT
cord-022561-rv5j1201	264	12	practicing	practice	VBG
cord-022561-rv5j1201	264	13	veterinarian	veterinarian	NN
cord-022561-rv5j1201	264	14	.	.	.
cord-022561-rv5j1201	265	1	The	the	DT
cord-022561-rv5j1201	265	2	CBC	CBC	NNP
cord-022561-rv5j1201	265	3	also	also	RB
cord-022561-rv5j1201	265	4	may	may	MD
cord-022561-rv5j1201	265	5	include	include	VB
cord-022561-rv5j1201	265	6	the	the	DT
cord-022561-rv5j1201	265	7	plasma	plasma	NN
cord-022561-rv5j1201	265	8	protein	protein	NN
cord-022561-rv5j1201	265	9	concentration	concentration	NN
cord-022561-rv5j1201	265	10	,	,	,
cord-022561-rv5j1201	265	11	as	as	IN
cord-022561-rv5j1201	265	12	measured	measure	VBN
cord-022561-rv5j1201	265	13	with	with	IN
cord-022561-rv5j1201	265	14	a	a	DT
cord-022561-rv5j1201	265	15	refractometer	refractometer	NN
cord-022561-rv5j1201	265	16	.	.	.
cord-022561-rv5j1201	266	1	It	-PRON-	PRP
cord-022561-rv5j1201	266	2	is	be	VBZ
cord-022561-rv5j1201	266	3	important	important	JJ
cord-022561-rv5j1201	266	4	to	to	TO
cord-022561-rv5j1201	266	5	remember	remember	VB
cord-022561-rv5j1201	266	6	that	that	IN
cord-022561-rv5j1201	266	7	changes	change	NNS
cord-022561-rv5j1201	266	8	in	in	IN
cord-022561-rv5j1201	266	9	hydration	hydration	NN
cord-022561-rv5j1201	266	10	status	status	NN
cord-022561-rv5j1201	266	11	and	and	CC
cord-022561-rv5j1201	266	12	in	in	IN
cord-022561-rv5j1201	266	13	the	the	DT
cord-022561-rv5j1201	266	14	distribution	distribution	NN
cord-022561-rv5j1201	266	15	of	of	IN
cord-022561-rv5j1201	266	16	body	body	NN
cord-022561-rv5j1201	266	17	fluids	fluid	NNS
cord-022561-rv5j1201	266	18	between	between	IN
cord-022561-rv5j1201	266	19	the	the	DT
cord-022561-rv5j1201	266	20	vascular	vascular	JJ
cord-022561-rv5j1201	266	21	and	and	CC
cord-022561-rv5j1201	266	22	extravascular	extravascular	JJ
cord-022561-rv5j1201	266	23	compartments	compartment	NNS
cord-022561-rv5j1201	266	24	affect	affect	VBP
cord-022561-rv5j1201	266	25	the	the	DT
cord-022561-rv5j1201	266	26	concentration	concentration	NN
cord-022561-rv5j1201	266	27	of	of	IN
cord-022561-rv5j1201	266	28	both	both	DT
cord-022561-rv5j1201	266	29	cells	cell	NNS
cord-022561-rv5j1201	266	30	and	and	CC
cord-022561-rv5j1201	266	31	proteins	protein	NNS
cord-022561-rv5j1201	266	32	in	in	IN
cord-022561-rv5j1201	266	33	the	the	DT
cord-022561-rv5j1201	266	34	blood	blood	NN
cord-022561-rv5j1201	266	35	.	.	.
cord-022561-rv5j1201	267	1	Other	other	JJ
cord-022561-rv5j1201	267	2	tests	test	NNS
cord-022561-rv5j1201	267	3	that	that	WDT
cord-022561-rv5j1201	267	4	may	may	MD
cord-022561-rv5j1201	267	5	help	help	VB
cord-022561-rv5j1201	267	6	with	with	IN
cord-022561-rv5j1201	267	7	evaluation	evaluation	NN
cord-022561-rv5j1201	267	8	of	of	IN
cord-022561-rv5j1201	267	9	the	the	DT
cord-022561-rv5j1201	267	10	hematopoietic	hematopoietic	JJ
cord-022561-rv5j1201	267	11	system	system	NN
cord-022561-rv5j1201	267	12	include	include	VBP
cord-022561-rv5j1201	267	13	cell	cell	NN
cord-022561-rv5j1201	267	14	or	or	CC
cord-022561-rv5j1201	267	15	tissue	tissue	NN
cord-022561-rv5j1201	267	16	biopsies	biopsy	NNS
cord-022561-rv5j1201	267	17	,	,	,
cord-022561-rv5j1201	267	18	the	the	DT
cord-022561-rv5j1201	267	19	direct	direct	JJ
cord-022561-rv5j1201	267	20	antiglobulin	antiglobulin	NN
cord-022561-rv5j1201	267	21	test	test	NN
cord-022561-rv5j1201	267	22	,	,	,
cord-022561-rv5j1201	267	23	flow	flow	NN
cord-022561-rv5j1201	267	24	cytometry	cytometry	NN
cord-022561-rv5j1201	267	25	,	,	,
cord-022561-rv5j1201	267	26	immunophenotyping	immunophenotyping	NN
cord-022561-rv5j1201	267	27	,	,	,
cord-022561-rv5j1201	267	28	and	and	CC
cord-022561-rv5j1201	267	29	polymerase	polymerase	NN
cord-022561-rv5j1201	267	30	chain	chain	NN
cord-022561-rv5j1201	267	31	reaction	reaction	NN
cord-022561-rv5j1201	267	32	(	(	-LRB-
cord-022561-rv5j1201	267	33	PCR	PCR	NNP
cord-022561-rv5j1201	267	34	)	)	-RRB-
cord-022561-rv5j1201	267	35	.	.	.
cord-022561-rv5j1201	268	1	Aspiration	aspiration	NN
cord-022561-rv5j1201	268	2	cytology	cytology	NN
cord-022561-rv5j1201	268	3	and/or	and/or	CC
cord-022561-rv5j1201	268	4	histopathology	histopathology	NN
cord-022561-rv5j1201	268	5	of	of	IN
cord-022561-rv5j1201	268	6	organs	organ	NNS
cord-022561-rv5j1201	269	1	other	other	JJ
cord-022561-rv5j1201	269	2	than	than	IN
cord-022561-rv5j1201	269	3	the	the	DT
cord-022561-rv5j1201	269	4	bone	bone	NN
cord-022561-rv5j1201	269	5	marrow	marrow	NN
cord-022561-rv5j1201	269	6	can	can	MD
cord-022561-rv5j1201	269	7	be	be	VB
cord-022561-rv5j1201	269	8	pursued	pursue	VBN
cord-022561-rv5j1201	269	9	to	to	TO
cord-022561-rv5j1201	269	10	assess	assess	VB
cord-022561-rv5j1201	269	11	for	for	IN
cord-022561-rv5j1201	269	12	the	the	DT
cord-022561-rv5j1201	269	13	presence	presence	NN
cord-022561-rv5j1201	269	14	of	of	IN
cord-022561-rv5j1201	269	15	EMH	EMH	NNP
cord-022561-rv5j1201	269	16	,	,	,
cord-022561-rv5j1201	269	17	increased	increase	VBN
cord-022561-rv5j1201	269	18	destruction	destruction	NN
cord-022561-rv5j1201	269	19	of	of	IN
cord-022561-rv5j1201	269	20	erythrocytes	erythrocyte	NNS
cord-022561-rv5j1201	269	21	,	,	,
cord-022561-rv5j1201	269	22	neoplasia	neoplasia	NN
cord-022561-rv5j1201	269	23	,	,	,
cord-022561-rv5j1201	269	24	or	or	CC
cord-022561-rv5j1201	269	25	infection	infection	NN
cord-022561-rv5j1201	269	26	.	.	.
cord-022561-rv5j1201	270	1	The	the	DT
cord-022561-rv5j1201	270	2	Coombs	Coombs	NNP
cord-022561-rv5j1201	270	3	test	test	NN
cord-022561-rv5j1201	270	4	,	,	,
cord-022561-rv5j1201	270	5	or	or	CC
cord-022561-rv5j1201	270	6	direct	direct	JJ
cord-022561-rv5j1201	270	7	antiglobulin	antiglobulin	NN
cord-022561-rv5j1201	270	8	test	test	NN
cord-022561-rv5j1201	270	9	,	,	,
cord-022561-rv5j1201	270	10	detects	detect	VBZ
cord-022561-rv5j1201	270	11	excessive	excessive	JJ
cord-022561-rv5j1201	270	12	antibody	antibody	NN
cord-022561-rv5j1201	270	13	or	or	CC
cord-022561-rv5j1201	270	14	complement	complement	VB
cord-022561-rv5j1201	270	15	bound	bind	VBN
cord-022561-rv5j1201	270	16	to	to	IN
cord-022561-rv5j1201	270	17	red	red	JJ
cord-022561-rv5j1201	270	18	blood	blood	NN
cord-022561-rv5j1201	270	19	cells	cell	NNS
cord-022561-rv5j1201	270	20	'	'	POS
cord-022561-rv5j1201	270	21	surfaces	surface	NNS
cord-022561-rv5j1201	270	22	and	and	CC
cord-022561-rv5j1201	270	23	is	be	VBZ
cord-022561-rv5j1201	270	24	the	the	DT
cord-022561-rv5j1201	270	25	standard	standard	JJ
cord-022561-rv5j1201	270	26	assay	assay	NN
cord-022561-rv5j1201	270	27	for	for	IN
cord-022561-rv5j1201	270	28	immune	immune	NN
cord-022561-rv5j1201	270	29	-	-	HYPH
cord-022561-rv5j1201	270	30	mediated	mediate	VBN
cord-022561-rv5j1201	270	31	hemolytic	hemolytic	JJ
cord-022561-rv5j1201	270	32	anemia	anemia	NN
cord-022561-rv5j1201	270	33	.	.	.
cord-022561-rv5j1201	271	1	Flow	flow	NN
cord-022561-rv5j1201	271	2	cytometry	cytometry	NN
cord-022561-rv5j1201	271	3	and	and	CC
cord-022561-rv5j1201	271	4	immunofluorescent	immunofluorescent	JJ
cord-022561-rv5j1201	271	5	antibody	antibody	NN
cord-022561-rv5j1201	271	6	tests	test	NNS
cord-022561-rv5j1201	271	7	may	may	MD
cord-022561-rv5j1201	271	8	also	also	RB
cord-022561-rv5j1201	271	9	be	be	VB
cord-022561-rv5j1201	271	10	used	use	VBN
cord-022561-rv5j1201	271	11	to	to	TO
cord-022561-rv5j1201	271	12	detect	detect	VB
cord-022561-rv5j1201	271	13	autoantibody	autoantibody	NN
cord-022561-rv5j1201	271	14	bound	bind	VBN
cord-022561-rv5j1201	271	15	to	to	IN
cord-022561-rv5j1201	271	16	erythrocytes	erythrocyte	NNS
cord-022561-rv5j1201	271	17	or	or	CC
cord-022561-rv5j1201	271	18	other	other	JJ
cord-022561-rv5j1201	271	19	hematopoietic	hematopoietic	JJ
cord-022561-rv5j1201	271	20	cells	cell	NNS
cord-022561-rv5j1201	271	21	.	.	.
cord-022561-rv5j1201	272	1	Immunophenotyping	Immunophenotyping	NNP
cord-022561-rv5j1201	272	2	and	and	CC
cord-022561-rv5j1201	272	3	PCR	PCR	NNP
cord-022561-rv5j1201	272	4	are	be	VBP
cord-022561-rv5j1201	272	5	further	further	RB
cord-022561-rv5j1201	272	6	discussed	discuss	VBN
cord-022561-rv5j1201	272	7	in	in	IN
cord-022561-rv5j1201	272	8	the	the	DT
cord-022561-rv5j1201	272	9	section	section	NN
cord-022561-rv5j1201	272	10	on	on	IN
cord-022561-rv5j1201	272	11	Hematopoietic	Hematopoietic	NNP
cord-022561-rv5j1201	272	12	Neoplasia	Neoplasia	NNP
cord-022561-rv5j1201	272	13	.	.	.
cord-022561-rv5j1201	273	1	Structural	structural	JJ
cord-022561-rv5j1201	273	2	or	or	CC
cord-022561-rv5j1201	273	3	functional	functional	JJ
cord-022561-rv5j1201	273	4	abnormalities	abnormality	NNS
cord-022561-rv5j1201	273	5	of	of	IN
cord-022561-rv5j1201	273	6	blood	blood	NN
cord-022561-rv5j1201	273	7	vessels	vessel	NNS
cord-022561-rv5j1201	273	8	,	,	,
cord-022561-rv5j1201	273	9	platelets	platelet	NNS
cord-022561-rv5j1201	273	10	,	,	,
cord-022561-rv5j1201	273	11	or	or	CC
cord-022561-rv5j1201	273	12	coagulation	coagulation	NN
cord-022561-rv5j1201	273	13	factors	factor	NNS
cord-022561-rv5j1201	273	14	may	may	MD
cord-022561-rv5j1201	273	15	result	result	VB
cord-022561-rv5j1201	273	16	in	in	IN
cord-022561-rv5j1201	273	17	a	a	DT
cord-022561-rv5j1201	273	18	tendency	tendency	NN
cord-022561-rv5j1201	273	19	toward	toward	IN
cord-022561-rv5j1201	273	20	hypocoagulability	hypocoagulability	NN
cord-022561-rv5j1201	273	21	(	(	-LRB-
cord-022561-rv5j1201	273	22	bleeding	bleed	VBG
cord-022561-rv5j1201	273	23	)	)	-RRB-
cord-022561-rv5j1201	273	24	,	,	,
cord-022561-rv5j1201	273	25	hypercoagulability	hypercoagulability	NN
cord-022561-rv5j1201	273	26	(	(	-LRB-
cord-022561-rv5j1201	273	27	inappropriate	inappropriate	JJ
cord-022561-rv5j1201	273	28	thrombosis	thrombosis	NN
cord-022561-rv5j1201	273	29	)	)	-RRB-
cord-022561-rv5j1201	273	30	,	,	,
cord-022561-rv5j1201	273	31	or	or	CC
cord-022561-rv5j1201	273	32	both	both	DT
cord-022561-rv5j1201	273	33	.	.	.
cord-022561-rv5j1201	274	1	In	in	IN
cord-022561-rv5j1201	274	2	veterinary	veterinary	JJ
cord-022561-rv5j1201	274	3	medicine	medicine	NN
cord-022561-rv5j1201	274	4	there	there	EX
cord-022561-rv5j1201	274	5	has	have	VBZ
cord-022561-rv5j1201	274	6	been	be	VBN
cord-022561-rv5j1201	274	7	a	a	DT
cord-022561-rv5j1201	274	8	great	great	JJ
cord-022561-rv5j1201	274	9	deal	deal	NN
cord-022561-rv5j1201	274	10	of	of	IN
cord-022561-rv5j1201	274	11	work	work	NN
cord-022561-rv5j1201	274	12	on	on	IN
cord-022561-rv5j1201	274	13	specific	specific	JJ
cord-022561-rv5j1201	274	14	mechanisms	mechanism	NNS
cord-022561-rv5j1201	274	15	of	of	IN
cord-022561-rv5j1201	274	16	hypocoagulability	hypocoagulability	NN
cord-022561-rv5j1201	274	17	,	,	,
cord-022561-rv5j1201	274	18	whereas	whereas	IN
cord-022561-rv5j1201	274	19	mechanisms	mechanism	NNS
cord-022561-rv5j1201	274	20	of	of	IN
cord-022561-rv5j1201	274	21	hypercoagulability	hypercoagulability	NN
cord-022561-rv5j1201	274	22	are	be	VBP
cord-022561-rv5j1201	274	23	less	less	RBR
cord-022561-rv5j1201	274	24	fully	fully	RB
cord-022561-rv5j1201	274	25	characterized	characterize	VBN
cord-022561-rv5j1201	274	26	.	.	.
cord-022561-rv5j1201	275	1	Disorders	disorder	NNS
cord-022561-rv5j1201	275	2	of	of	IN
cord-022561-rv5j1201	275	3	primary	primary	JJ
cord-022561-rv5j1201	275	4	hemostasis	hemostasis	NN
cord-022561-rv5j1201	275	5	typically	typically	RB
cord-022561-rv5j1201	275	6	result	result	VBP
cord-022561-rv5j1201	275	7	in	in	IN
cord-022561-rv5j1201	275	8	"	"	``
cord-022561-rv5j1201	275	9	small	small	JJ
cord-022561-rv5j1201	275	10	bleeds	bleed	NNS
cord-022561-rv5j1201	275	11	"	"	''
cord-022561-rv5j1201	275	12	(	(	-LRB-
cord-022561-rv5j1201	275	13	e.g.	e.g.	RB
cord-022561-rv5j1201	275	14	,	,	,
cord-022561-rv5j1201	275	15	petechiation	petechiation	NN
cord-022561-rv5j1201	275	16	,	,	,
cord-022561-rv5j1201	275	17	mild	mild	JJ
cord-022561-rv5j1201	275	18	ecchymosis	ecchymosis	NN
cord-022561-rv5j1201	275	19	,	,	,
cord-022561-rv5j1201	275	20	bleeding	bleed	VBG
cord-022561-rv5j1201	275	21	from	from	IN
cord-022561-rv5j1201	275	22	mucous	mucous	JJ
cord-022561-rv5j1201	275	23	membranes	membrane	NNS
cord-022561-rv5j1201	275	24	,	,	,
cord-022561-rv5j1201	275	25	bleeding	bleed	VBG
cord-022561-rv5j1201	275	26	immediately	immediately	RB
cord-022561-rv5j1201	275	27	after	after	IN
cord-022561-rv5j1201	275	28	venipuncture	venipuncture	NN
cord-022561-rv5j1201	275	29	)	)	-RRB-
cord-022561-rv5j1201	275	30	,	,	,
cord-022561-rv5j1201	275	31	whereas	whereas	IN
cord-022561-rv5j1201	275	32	disorders	disorder	NNS
cord-022561-rv5j1201	275	33	of	of	IN
cord-022561-rv5j1201	275	34	secondary	secondary	JJ
cord-022561-rv5j1201	275	35	hemostasis	hemostasis	NN
cord-022561-rv5j1201	275	36	typically	typically	RB
cord-022561-rv5j1201	275	37	result	result	VBP
cord-022561-rv5j1201	275	38	in	in	IN
cord-022561-rv5j1201	275	39	"	"	``
cord-022561-rv5j1201	275	40	big	big	JJ
cord-022561-rv5j1201	275	41	bleeds	bleed	NNS
cord-022561-rv5j1201	275	42	"	"	''
cord-022561-rv5j1201	275	43	(	(	-LRB-
cord-022561-rv5j1201	275	44	e.g.	e.g.	RB
cord-022561-rv5j1201	275	45	,	,	,
cord-022561-rv5j1201	275	46	hemorrhage	hemorrhage	NN
cord-022561-rv5j1201	275	47	into	into	IN
cord-022561-rv5j1201	275	48	body	body	NN
cord-022561-rv5j1201	275	49	cavities/	cavities/	CD
cord-022561-rv5j1201	275	50	joints	joint	NNS
cord-022561-rv5j1201	275	51	,	,	,
cord-022561-rv5j1201	275	52	marked	mark	VBN
cord-022561-rv5j1201	275	53	ecchymosis	ecchymosis	NN
cord-022561-rv5j1201	275	54	,	,	,
cord-022561-rv5j1201	275	55	large	large	JJ
cord-022561-rv5j1201	275	56	hematomas	hematoma	NNS
cord-022561-rv5j1201	275	57	,	,	,
cord-022561-rv5j1201	275	58	delayed	delay	VBN
cord-022561-rv5j1201	275	59	bleeding	bleeding	NN
cord-022561-rv5j1201	275	60	after	after	IN
cord-022561-rv5j1201	275	61	venipuncture	venipuncture	NN
cord-022561-rv5j1201	275	62	)	)	-RRB-
cord-022561-rv5j1201	275	63	.	.	.
cord-022561-rv5j1201	276	1	This	this	DT
cord-022561-rv5j1201	276	2	chapter	chapter	NN
cord-022561-rv5j1201	276	3	concentrates	concentrate	VBZ
cord-022561-rv5j1201	276	4	on	on	IN
cord-022561-rv5j1201	276	5	primary	primary	JJ
cord-022561-rv5j1201	276	6	disorders	disorder	NNS
cord-022561-rv5j1201	276	7	of	of	IN
cord-022561-rv5j1201	276	8	hemostasis	hemostasis	NN
cord-022561-rv5j1201	276	9	and	and	CC
cord-022561-rv5j1201	276	10	also	also	RB
cord-022561-rv5j1201	276	11	covers	cover	VBZ
cord-022561-rv5j1201	276	12	disseminated	disseminate	VBN
cord-022561-rv5j1201	276	13	intravascular	intravascular	JJ
cord-022561-rv5j1201	276	14	coagulation	coagulation	NN
cord-022561-rv5j1201	276	15	,	,	,
cord-022561-rv5j1201	276	16	which	which	WDT
cord-022561-rv5j1201	276	17	is	be	VBZ
cord-022561-rv5j1201	276	18	the	the	DT
cord-022561-rv5j1201	276	19	secondary	secondary	JJ
cord-022561-rv5j1201	276	20	condition	condition	NN
cord-022561-rv5j1201	276	21	.	.	.
cord-022561-rv5j1201	277	1	However	however	RB
cord-022561-rv5j1201	277	2	,	,	,
cord-022561-rv5j1201	277	3	it	-PRON-	PRP
cord-022561-rv5j1201	277	4	is	be	VBZ
cord-022561-rv5j1201	277	5	important	important	JJ
cord-022561-rv5j1201	277	6	to	to	TO
cord-022561-rv5j1201	277	7	note	note	VB
cord-022561-rv5j1201	277	8	that	that	IN
cord-022561-rv5j1201	277	9	coagulation	coagulation	NN
cord-022561-rv5j1201	277	10	disorders	disorder	NNS
cord-022561-rv5j1201	277	11	can	can	MD
cord-022561-rv5j1201	277	12	also	also	RB
cord-022561-rv5j1201	277	13	result	result	VB
cord-022561-rv5j1201	277	14	from	from	IN
cord-022561-rv5j1201	277	15	other	other	JJ
cord-022561-rv5j1201	277	16	underlying	underlie	VBG
cord-022561-rv5j1201	277	17	disease	disease	NN
cord-022561-rv5j1201	277	18	processes	process	NNS
cord-022561-rv5j1201	277	19	.	.	.
cord-022561-rv5j1201	278	1	For	for	IN
cord-022561-rv5j1201	278	2	example	example	NN
cord-022561-rv5j1201	278	3	,	,	,
cord-022561-rv5j1201	278	4	advanced	advanced	JJ
cord-022561-rv5j1201	278	5	liver	liver	NN
cord-022561-rv5j1201	278	6	disease	disease	NN
cord-022561-rv5j1201	278	7	can	can	MD
cord-022561-rv5j1201	278	8	lead	lead	VB
cord-022561-rv5j1201	278	9	to	to	IN
cord-022561-rv5j1201	278	10	abnormal	abnormal	JJ
cord-022561-rv5j1201	278	11	hemostasis	hemostasis	NN
cord-022561-rv5j1201	278	12	through	through	IN
cord-022561-rv5j1201	278	13	decreased	decreased	JJ
cord-022561-rv5j1201	278	14	or	or	CC
cord-022561-rv5j1201	278	15	defective	defective	JJ
cord-022561-rv5j1201	278	16	synthesis	synthesis	NN
cord-022561-rv5j1201	278	17	of	of	IN
cord-022561-rv5j1201	278	18	coagulation	coagulation	NN
cord-022561-rv5j1201	278	19	factors	factor	NNS
cord-022561-rv5j1201	278	20	or	or	CC
cord-022561-rv5j1201	278	21	impaired	impaired	JJ
cord-022561-rv5j1201	278	22	clearance	clearance	NN
cord-022561-rv5j1201	278	23	of	of	IN
cord-022561-rv5j1201	278	24	fibrinolytic	fibrinolytic	JJ
cord-022561-rv5j1201	278	25	products	product	NNS
cord-022561-rv5j1201	278	26	that	that	WDT
cord-022561-rv5j1201	278	27	inhibit	inhibit	VBP
cord-022561-rv5j1201	278	28	coagulation	coagulation	NN
cord-022561-rv5j1201	278	29	reactions	reaction	NNS
cord-022561-rv5j1201	278	30	and	and	CC
cord-022561-rv5j1201	278	31	platelet	platelet	NN
cord-022561-rv5j1201	278	32	function	function	NN
cord-022561-rv5j1201	278	33	.	.	.
cord-022561-rv5j1201	279	1	Vascular	vascular	JJ
cord-022561-rv5j1201	279	2	disorders	disorder	NNS
cord-022561-rv5j1201	279	3	may	may	MD
cord-022561-rv5j1201	279	4	also	also	RB
cord-022561-rv5j1201	279	5	result	result	VB
cord-022561-rv5j1201	279	6	in	in	IN
cord-022561-rv5j1201	279	7	a	a	DT
cord-022561-rv5j1201	279	8	bleeding	bleeding	JJ
cord-022561-rv5j1201	279	9	tendency	tendency	NN
cord-022561-rv5j1201	279	10	because	because	IN
cord-022561-rv5j1201	279	11	of	of	IN
cord-022561-rv5j1201	279	12	abnormalities	abnormality	NNS
cord-022561-rv5j1201	279	13	of	of	IN
cord-022561-rv5j1201	279	14	endothelial	endothelial	JJ
cord-022561-rv5j1201	279	15	function	function	NN
cord-022561-rv5j1201	279	16	or	or	CC
cord-022561-rv5j1201	279	17	collagen	collagen	NN
cord-022561-rv5j1201	279	18	-	-	HYPH
cord-022561-rv5j1201	279	19	platelet	platelet	NN
cord-022561-rv5j1201	279	20	interactions	interaction	NNS
cord-022561-rv5j1201	279	21	.	.	.
cord-022561-rv5j1201	280	1	Specific	specific	JJ
cord-022561-rv5j1201	280	2	diseases	disease	NNS
cord-022561-rv5j1201	280	3	involving	involve	VBG
cord-022561-rv5j1201	280	4	abnormal	abnormal	JJ
cord-022561-rv5j1201	280	5	structure	structure	NN
cord-022561-rv5j1201	280	6	or	or	CC
cord-022561-rv5j1201	280	7	function	function	NN
cord-022561-rv5j1201	280	8	of	of	IN
cord-022561-rv5j1201	280	9	hematopoietic	hematopoietic	JJ
cord-022561-rv5j1201	280	10	or	or	CC
cord-022561-rv5j1201	280	11	hemostatic	hemostatic	JJ
cord-022561-rv5j1201	280	12	elements	element	NNS
cord-022561-rv5j1201	280	13	are	be	VBP
cord-022561-rv5j1201	280	14	discussed	discuss	VBN
cord-022561-rv5j1201	280	15	later	later	RB
cord-022561-rv5j1201	280	16	in	in	IN
cord-022561-rv5j1201	280	17	this	this	DT
cord-022561-rv5j1201	280	18	chapter	chapter	NN
cord-022561-rv5j1201	280	19	.	.	.
cord-022561-rv5j1201	281	1	The	the	DT
cord-022561-rv5j1201	281	2	CBC	CBC	NNP
cord-022561-rv5j1201	281	3	provides	provide	VBZ
cord-022561-rv5j1201	281	4	basic	basic	JJ
cord-022561-rv5j1201	281	5	information	information	NN
cord-022561-rv5j1201	281	6	about	about	IN
cord-022561-rv5j1201	281	7	platelets	platelet	NNS
cord-022561-rv5j1201	281	8	,	,	,
cord-022561-rv5j1201	281	9	including	include	VBG
cord-022561-rv5j1201	281	10	numeric	numeric	JJ
cord-022561-rv5j1201	281	11	values	value	NNS
cord-022561-rv5j1201	281	12	for	for	IN
cord-022561-rv5j1201	281	13	platelet	platelet	NN
cord-022561-rv5j1201	281	14	concentration	concentration	NN
cord-022561-rv5j1201	281	15	and	and	CC
cord-022561-rv5j1201	281	16	mean	mean	JJ
cord-022561-rv5j1201	281	17	platelet	platelet	NN
cord-022561-rv5j1201	281	18	volume	volume	NN
cord-022561-rv5j1201	281	19	(	(	-LRB-
cord-022561-rv5j1201	281	20	MPV	MPV	NNP
cord-022561-rv5j1201	281	21	)	)	-RRB-
cord-022561-rv5j1201	281	22	,	,	,
cord-022561-rv5j1201	281	23	subjective	subjective	JJ
cord-022561-rv5j1201	281	24	assessment	assessment	NN
cord-022561-rv5j1201	281	25	of	of	IN
cord-022561-rv5j1201	281	26	platelet	platelet	NN
cord-022561-rv5j1201	281	27	morphologic	morphologic	JJ
cord-022561-rv5j1201	281	28	features	feature	NNS
cord-022561-rv5j1201	281	29	(	(	-LRB-
cord-022561-rv5j1201	281	30	size	size	NN
cord-022561-rv5j1201	281	31	,	,	,
cord-022561-rv5j1201	281	32	shape	shape	NN
cord-022561-rv5j1201	281	33	,	,	,
cord-022561-rv5j1201	281	34	and	and	CC
cord-022561-rv5j1201	281	35	granularity	granularity	NN
cord-022561-rv5j1201	281	36	)	)	-RRB-
cord-022561-rv5j1201	281	37	,	,	,
cord-022561-rv5j1201	281	38	and	and	CC
cord-022561-rv5j1201	281	39	a	a	DT
cord-022561-rv5j1201	281	40	rough	rough	JJ
cord-022561-rv5j1201	281	41	estimation	estimation	NN
cord-022561-rv5j1201	281	42	of	of	IN
cord-022561-rv5j1201	281	43	platelet	platelet	NN
cord-022561-rv5j1201	281	44	numbers	number	NNS
cord-022561-rv5j1201	281	45	based	base	VBN
cord-022561-rv5j1201	281	46	on	on	IN
cord-022561-rv5j1201	281	47	examination	examination	NN
cord-022561-rv5j1201	281	48	of	of	IN
cord-022561-rv5j1201	281	49	a	a	DT
cord-022561-rv5j1201	281	50	blood	blood	NN
cord-022561-rv5j1201	281	51	smear	smear	NN
cord-022561-rv5j1201	281	52	.	.	.
cord-022561-rv5j1201	282	1	Some	some	DT
cord-022561-rv5j1201	282	2	laboratories	laboratory	NNS
cord-022561-rv5j1201	282	3	measure	measure	VBP
cord-022561-rv5j1201	282	4	reticulated	reticulated	JJ
cord-022561-rv5j1201	282	5	platelets	platelet	NNS
cord-022561-rv5j1201	282	6	(	(	-LRB-
cord-022561-rv5j1201	282	7	platelets	platelet	NNS
cord-022561-rv5j1201	282	8	recently	recently	RB
cord-022561-rv5j1201	282	9	released	release	VBN
cord-022561-rv5j1201	282	10	from	from	IN
cord-022561-rv5j1201	282	11	the	the	DT
cord-022561-rv5j1201	282	12	bone	bone	NN
cord-022561-rv5j1201	282	13	marrow	marrow	NN
cord-022561-rv5j1201	282	14	)	)	-RRB-
cord-022561-rv5j1201	282	15	,	,	,
cord-022561-rv5j1201	282	16	although	although	IN
cord-022561-rv5j1201	282	17	this	this	DT
cord-022561-rv5j1201	282	18	test	test	NN
cord-022561-rv5j1201	282	19	is	be	VBZ
cord-022561-rv5j1201	282	20	mostly	mostly	RB
cord-022561-rv5j1201	282	21	used	use	VBN
cord-022561-rv5j1201	282	22	in	in	IN
cord-022561-rv5j1201	282	23	the	the	DT
cord-022561-rv5j1201	282	24	research	research	NN
cord-022561-rv5j1201	282	25	setting	set	VBG
cord-022561-rv5j1201	282	26	at	at	IN
cord-022561-rv5j1201	282	27	present	present	NN
cord-022561-rv5j1201	282	28	.	.	.
cord-022561-rv5j1201	283	1	Increased	increase	VBN
cord-022561-rv5j1201	283	2	MPV	mpv	NN
cord-022561-rv5j1201	283	3	and	and	CC
cord-022561-rv5j1201	283	4	increased	increase	VBN
cord-022561-rv5j1201	283	5	numbers	number	NNS
cord-022561-rv5j1201	283	6	of	of	IN
cord-022561-rv5j1201	283	7	reticulated	reticulated	JJ
cord-022561-rv5j1201	283	8	platelets	platelet	NNS
cord-022561-rv5j1201	283	9	tend	tend	VBP
cord-022561-rv5j1201	283	10	to	to	TO
cord-022561-rv5j1201	283	11	indicate	indicate	VB
cord-022561-rv5j1201	283	12	increased	increase	VBN
cord-022561-rv5j1201	283	13	thrombopoiesis	thrombopoiesis	NNP
cord-022561-rv5j1201	283	14	.	.	.
cord-022561-rv5j1201	284	1	Bone	bone	NN
cord-022561-rv5j1201	284	2	marrow	marrow	NN
cord-022561-rv5j1201	284	3	examination	examination	NN
cord-022561-rv5j1201	284	4	is	be	VBZ
cord-022561-rv5j1201	284	5	indicated	indicate	VBN
cord-022561-rv5j1201	284	6	with	with	IN
cord-022561-rv5j1201	284	7	any	any	DT
cord-022561-rv5j1201	284	8	unexplained	unexplained	JJ
cord-022561-rv5j1201	284	9	cytopenia	cytopenia	NNS
cord-022561-rv5j1201	284	10	,	,	,
cord-022561-rv5j1201	284	11	including	include	VBG
cord-022561-rv5j1201	284	12	thrombocytopenia	thrombocytopenia	NN
cord-022561-rv5j1201	284	13	,	,	,
cord-022561-rv5j1201	284	14	to	to	TO
cord-022561-rv5j1201	284	15	evaluate	evaluate	VB
cord-022561-rv5j1201	284	16	production	production	NN
cord-022561-rv5j1201	284	17	.	.	.
cord-022561-rv5j1201	285	1	Tests	test	NNS
cord-022561-rv5j1201	285	2	to	to	TO
cord-022561-rv5j1201	285	3	evaluate	evaluate	VB
cord-022561-rv5j1201	285	4	the	the	DT
cord-022561-rv5j1201	285	5	components	component	NNS
cord-022561-rv5j1201	285	6	of	of	IN
cord-022561-rv5j1201	285	7	the	the	DT
cord-022561-rv5j1201	285	8	hemostatic	hemostatic	JJ
cord-022561-rv5j1201	285	9	process	process	NN
cord-022561-rv5j1201	285	10	are	be	VBP
cord-022561-rv5j1201	285	11	described	describe	VBN
cord-022561-rv5j1201	285	12	and	and	CC
cord-022561-rv5j1201	285	13	listed	list	VBN
cord-022561-rv5j1201	285	14	in	in	IN
cord-022561-rv5j1201	285	15	E	E	NNP
cord-022561-rv5j1201	285	16	-	-	NNP
cord-022561-rv5j1201	285	17	Appendix	Appendix	NNP
cord-022561-rv5j1201	285	18	13	13	CD
cord-022561-rv5j1201	285	19	-	-	SYM
cord-022561-rv5j1201	285	20	1	1	CD
cord-022561-rv5j1201	285	21	.	.	.
cord-022561-rv5j1201	286	1	Secondary	secondary	JJ
cord-022561-rv5j1201	286	2	myelofibrosis	myelofibrosis	NN
cord-022561-rv5j1201	286	3	is	be	VBZ
cord-022561-rv5j1201	286	4	the	the	DT
cord-022561-rv5j1201	286	5	enhanced	enhanced	JJ
cord-022561-rv5j1201	286	6	deposition	deposition	NN
cord-022561-rv5j1201	286	7	of	of	IN
cord-022561-rv5j1201	286	8	collagen	collagen	NN
cord-022561-rv5j1201	286	9	within	within	IN
cord-022561-rv5j1201	286	10	the	the	DT
cord-022561-rv5j1201	286	11	marrow	marrow	NN
cord-022561-rv5j1201	286	12	by	by	IN
cord-022561-rv5j1201	286	13	nonneoplastic	nonneoplastic	JJ
cord-022561-rv5j1201	286	14	fibroblasts	fibroblast	NNS
cord-022561-rv5j1201	286	15	and	and	CC
cord-022561-rv5j1201	286	16	reticular	reticular	JJ
cord-022561-rv5j1201	286	17	cells	cell	NNS
cord-022561-rv5j1201	286	18	.	.	.
cord-022561-rv5j1201	287	1	Disease	disease	NN
cord-022561-rv5j1201	287	2	pathogenesis	pathogenesis	NN
cord-022561-rv5j1201	287	3	is	be	VBZ
cord-022561-rv5j1201	287	4	unclear	unclear	JJ
cord-022561-rv5j1201	287	5	,	,	,
cord-022561-rv5j1201	287	6	but	but	CC
cord-022561-rv5j1201	287	7	there	there	EX
cord-022561-rv5j1201	287	8	are	be	VBP
cord-022561-rv5j1201	287	9	two	two	CD
cord-022561-rv5j1201	287	10	leading	lead	VBG
cord-022561-rv5j1201	287	11	theories	theory	NNS
cord-022561-rv5j1201	287	12	.	.	.
cord-022561-rv5j1201	288	1	First	first	RB
cord-022561-rv5j1201	288	2	,	,	,
cord-022561-rv5j1201	288	3	it	-PRON-	PRP
cord-022561-rv5j1201	288	4	may	may	MD
cord-022561-rv5j1201	288	5	represent	represent	VB
cord-022561-rv5j1201	288	6	scar	scar	NN
cord-022561-rv5j1201	288	7	formation	formation	NN
cord-022561-rv5j1201	288	8	after	after	IN
cord-022561-rv5j1201	288	9	marrow	marrow	NN
cord-022561-rv5j1201	288	10	necrosis	necrosis	NN
cord-022561-rv5j1201	288	11	,	,	,
cord-022561-rv5j1201	288	12	as	as	IN
cord-022561-rv5j1201	288	13	previously	previously	RB
cord-022561-rv5j1201	288	14	presented	present	VBN
cord-022561-rv5j1201	288	15	.	.	.
cord-022561-rv5j1201	289	1	And	and	CC
cord-022561-rv5j1201	289	2	second	second	JJ
cord-022561-rv5j1201	289	3	,	,	,
cord-022561-rv5j1201	289	4	high	high	JJ
cord-022561-rv5j1201	289	5	concentrations	concentration	NNS
cord-022561-rv5j1201	289	6	of	of	IN
cord-022561-rv5j1201	289	7	growth	growth	NN
cord-022561-rv5j1201	289	8	factors	factor	NNS
cord-022561-rv5j1201	289	9	present	present	VBP
cord-022561-rv5j1201	289	10	during	during	IN
cord-022561-rv5j1201	289	11	times	time	NNS
cord-022561-rv5j1201	289	12	of	of	IN
cord-022561-rv5j1201	289	13	marrow	marrow	NN
cord-022561-rv5j1201	289	14	injury	injury	NN
cord-022561-rv5j1201	289	15	or	or	CC
cord-022561-rv5j1201	289	16	activation	activation	NN
cord-022561-rv5j1201	289	17	may	may	MD
cord-022561-rv5j1201	289	18	stimulate	stimulate	VB
cord-022561-rv5j1201	289	19	fibroblast	fibroblast	NN
cord-022561-rv5j1201	289	20	proliferation	proliferation	NN
cord-022561-rv5j1201	289	21	.	.	.
cord-022561-rv5j1201	290	1	In	in	IN
cord-022561-rv5j1201	290	2	particular	particular	JJ
cord-022561-rv5j1201	290	3	,	,	,
cord-022561-rv5j1201	290	4	stimulated	stimulate	VBD
cord-022561-rv5j1201	290	5	megakaryocytes	megakaryocyte	NNS
cord-022561-rv5j1201	290	6	and	and	CC
cord-022561-rv5j1201	290	7	macrophages	macrophage	NNS
cord-022561-rv5j1201	290	8	produce	produce	VBP
cord-022561-rv5j1201	290	9	fibrogenic	fibrogenic	JJ
cord-022561-rv5j1201	290	10	cytokines	cytokine	NNS
cord-022561-rv5j1201	290	11	,	,	,
cord-022561-rv5j1201	290	12	including	include	VBG
cord-022561-rv5j1201	290	13	plateletderived	plateletderived	JJ
cord-022561-rv5j1201	290	14	growth	growth	NN
cord-022561-rv5j1201	290	15	factor	factor	NN
cord-022561-rv5j1201	290	16	,	,	,
cord-022561-rv5j1201	290	17	transforming	transform	VBG
cord-022561-rv5j1201	290	18	growth	growth	NN
cord-022561-rv5j1201	290	19	factor	factor	NN
cord-022561-rv5j1201	290	20	-	-	HYPH
cord-022561-rv5j1201	290	21	β	β	NN
cord-022561-rv5j1201	290	22	,	,	,
cord-022561-rv5j1201	290	23	and	and	CC
cord-022561-rv5j1201	290	24	epidermal	epidermal	JJ
cord-022561-rv5j1201	290	25	growth	growth	NN
cord-022561-rv5j1201	290	26	factor	factor	NN
cord-022561-rv5j1201	290	27	.	.	.
cord-022561-rv5j1201	291	1	Early	early	RB
cord-022561-rv5j1201	291	2	in	in	IN
cord-022561-rv5j1201	291	3	disease	disease	NN
cord-022561-rv5j1201	291	4	there	there	EX
cord-022561-rv5j1201	291	5	is	be	VBZ
cord-022561-rv5j1201	291	6	reticulin	reticulin	JJ
cord-022561-rv5j1201	291	7	deposition	deposition	NN
cord-022561-rv5j1201	291	8	without	without	IN
cord-022561-rv5j1201	291	9	reduction	reduction	NN
cord-022561-rv5j1201	291	10	of	of	IN
cord-022561-rv5j1201	291	11	hematopoietic	hematopoietic	JJ
cord-022561-rv5j1201	291	12	elements	element	NNS
cord-022561-rv5j1201	291	13	.	.	.
cord-022561-rv5j1201	292	1	However	however	RB
cord-022561-rv5j1201	292	2	,	,	,
cord-022561-rv5j1201	292	3	fibrous	fibrous	JJ
cord-022561-rv5j1201	292	4	collagen	collagen	NN
cord-022561-rv5j1201	292	5	replaces	replace	VBZ
cord-022561-rv5j1201	292	6	hematopoietic	hematopoietic	JJ
cord-022561-rv5j1201	292	7	cells	cell	NNS
cord-022561-rv5j1201	292	8	with	with	IN
cord-022561-rv5j1201	292	9	disease	disease	NN
cord-022561-rv5j1201	292	10	progression	progression	NN
cord-022561-rv5j1201	292	11	.	.	.
cord-022561-rv5j1201	293	1	Histologic	Histologic	NNP
cord-022561-rv5j1201	293	2	identification	identification	NN
cord-022561-rv5j1201	293	3	of	of	IN
cord-022561-rv5j1201	293	4	reticulin	reticulin	NN
cord-022561-rv5j1201	293	5	and	and	CC
cord-022561-rv5j1201	293	6	collagen	collagen	NN
cord-022561-rv5j1201	293	7	fibers	fiber	NNS
cord-022561-rv5j1201	293	8	can	can	MD
cord-022561-rv5j1201	293	9	be	be	VB
cord-022561-rv5j1201	293	10	aided	aid	VBN
cord-022561-rv5j1201	293	11	with	with	IN
cord-022561-rv5j1201	293	12	reticulin	reticulin	NNP
cord-022561-rv5j1201	293	13	silver	silver	NN
cord-022561-rv5j1201	293	14	and	and	CC
cord-022561-rv5j1201	293	15	Masson	Masson	NNP
cord-022561-rv5j1201	293	16	's	's	POS
cord-022561-rv5j1201	293	17	trichrome	trichrome	JJ
cord-022561-rv5j1201	293	18	stains	stain	NNS
cord-022561-rv5j1201	293	19	,	,	,
cord-022561-rv5j1201	293	20	respectively	respectively	RB
cord-022561-rv5j1201	293	21	.	.	.
cord-022561-rv5j1201	294	1	In	in	IN
cord-022561-rv5j1201	294	2	animals	animal	NNS
cord-022561-rv5j1201	294	3	,	,	,
cord-022561-rv5j1201	294	4	secondary	secondary	JJ
cord-022561-rv5j1201	294	5	myelofibrosis	myelofibrosis	NN
cord-022561-rv5j1201	294	6	occurs	occur	VBZ
cord-022561-rv5j1201	294	7	most	most	RBS
cord-022561-rv5j1201	294	8	commonly	commonly	RB
cord-022561-rv5j1201	294	9	with	with	IN
cord-022561-rv5j1201	294	10	leukemias	leukemia	NNS
cord-022561-rv5j1201	294	11	,	,	,
cord-022561-rv5j1201	294	12	extramarrow	extramarrow	NN
cord-022561-rv5j1201	294	13	malignancies	malignancy	NNS
cord-022561-rv5j1201	294	14	,	,	,
cord-022561-rv5j1201	294	15	and	and	CC
cord-022561-rv5j1201	294	16	chronic	chronic	JJ
cord-022561-rv5j1201	294	17	hemolytic	hemolytic	JJ
cord-022561-rv5j1201	294	18	anemias	anemia	NNS
cord-022561-rv5j1201	294	19	,	,	,
cord-022561-rv5j1201	294	20	but	but	CC
cord-022561-rv5j1201	294	21	many	many	JJ
cord-022561-rv5j1201	294	22	cases	case	NNS
cord-022561-rv5j1201	294	23	are	be	VBP
cord-022561-rv5j1201	294	24	idiopathic	idiopathic	JJ
cord-022561-rv5j1201	294	25	.	.	.
cord-022561-rv5j1201	295	1	Experimental	experimental	JJ
cord-022561-rv5j1201	295	2	whole	whole	JJ
cord-022561-rv5j1201	295	3	-	-	HYPH
cord-022561-rv5j1201	295	4	body	body	NN
cord-022561-rv5j1201	295	5	gamma	gamma	NN
cord-022561-rv5j1201	295	6	irradiation	irradiation	NN
cord-022561-rv5j1201	295	7	,	,	,
cord-022561-rv5j1201	295	8	dietary	dietary	JJ
cord-022561-rv5j1201	295	9	strontium-90	strontium-90	NN
cord-022561-rv5j1201	295	10	exposure	exposure	NN
cord-022561-rv5j1201	295	11	,	,	,
cord-022561-rv5j1201	295	12	and	and	CC
cord-022561-rv5j1201	295	13	certain	certain	JJ
cord-022561-rv5j1201	295	14	drugs	drug	NNS
cord-022561-rv5j1201	295	15	and	and	CC
cord-022561-rv5j1201	295	16	toxins	toxin	NNS
cord-022561-rv5j1201	295	17	can	can	MD
cord-022561-rv5j1201	295	18	also	also	RB
cord-022561-rv5j1201	295	19	induce	induce	VB
cord-022561-rv5j1201	295	20	myelofibrosis	myelofibrosi	NNS
cord-022561-rv5j1201	295	21	.	.	.
cord-022561-rv5j1201	296	1	The	the	DT
cord-022561-rv5j1201	296	2	responses	response	NNS
cord-022561-rv5j1201	296	3	of	of	IN
cord-022561-rv5j1201	296	4	marrow	marrow	NN
cord-022561-rv5j1201	296	5	adipocytes	adipocyte	NNS
cord-022561-rv5j1201	296	6	to	to	IN
cord-022561-rv5j1201	296	7	systemic	systemic	JJ
cord-022561-rv5j1201	296	8	and	and	CC
cord-022561-rv5j1201	296	9	localized	localized	JJ
cord-022561-rv5j1201	296	10	disease	disease	NN
cord-022561-rv5j1201	296	11	are	be	VBP
cord-022561-rv5j1201	296	12	under	under	IN
cord-022561-rv5j1201	296	13	current	current	JJ
cord-022561-rv5j1201	296	14	investigation	investigation	NN
cord-022561-rv5j1201	296	15	,	,	,
cord-022561-rv5j1201	296	16	especially	especially	RB
cord-022561-rv5j1201	296	17	in	in	IN
cord-022561-rv5j1201	296	18	relation	relation	NN
cord-022561-rv5j1201	296	19	to	to	IN
cord-022561-rv5j1201	296	20	energy	energy	NN
cord-022561-rv5j1201	296	21	metabolism	metabolism	NN
cord-022561-rv5j1201	296	22	,	,	,
cord-022561-rv5j1201	296	23	inflammation	inflammation	NN
cord-022561-rv5j1201	296	24	,	,	,
cord-022561-rv5j1201	296	25	and	and	CC
cord-022561-rv5j1201	296	26	bone	bone	NN
cord-022561-rv5j1201	296	27	trauma	trauma	NN
cord-022561-rv5j1201	296	28	.	.	.
cord-022561-rv5j1201	297	1	During	during	IN
cord-022561-rv5j1201	297	2	times	time	NNS
cord-022561-rv5j1201	297	3	of	of	IN
cord-022561-rv5j1201	297	4	severe	severe	JJ
cord-022561-rv5j1201	297	5	energy	energy	NN
cord-022561-rv5j1201	297	6	imbalance	imbalance	NN
cord-022561-rv5j1201	297	7	,	,	,
cord-022561-rv5j1201	297	8	such	such	JJ
cord-022561-rv5j1201	297	9	as	as	IN
cord-022561-rv5j1201	297	10	cachexia	cachexia	NN
cord-022561-rv5j1201	297	11	,	,	,
cord-022561-rv5j1201	297	12	the	the	DT
cord-022561-rv5j1201	297	13	marrow	marrow	NN
cord-022561-rv5j1201	297	14	may	may	MD
cord-022561-rv5j1201	297	15	undergo	undergo	VB
cord-022561-rv5j1201	297	16	serous	serous	JJ
cord-022561-rv5j1201	297	17	atrophy	atrophy	NN
cord-022561-rv5j1201	297	18	of	of	IN
cord-022561-rv5j1201	297	19	fat	fat	NN
cord-022561-rv5j1201	297	20	,	,	,
cord-022561-rv5j1201	297	21	also	also	RB
cord-022561-rv5j1201	297	22	known	know	VBN
cord-022561-rv5j1201	297	23	as	as	IN
cord-022561-rv5j1201	297	24	gelatinous	gelatinous	JJ
cord-022561-rv5j1201	297	25	marrow	marrow	NN
cord-022561-rv5j1201	297	26	transformation	transformation	NN
cord-022561-rv5j1201	297	27	(	(	-LRB-
cord-022561-rv5j1201	297	28	E-	E-	NNP
cord-022561-rv5j1201	297	29	Fig	Fig	NNP
cord-022561-rv5j1201	297	30	.	.	.
cord-022561-rv5j1201	298	1	13	13	CD
cord-022561-rv5j1201	298	2	-1	-1	CD
cord-022561-rv5j1201	298	3	)	)	-RRB-
cord-022561-rv5j1201	298	4	.	.	.
cord-022561-rv5j1201	299	1	The	the	DT
cord-022561-rv5j1201	299	2	pathogenesis	pathogenesis	NN
cord-022561-rv5j1201	299	3	of	of	IN
cord-022561-rv5j1201	299	4	this	this	DT
cord-022561-rv5j1201	299	5	phenomenon	phenomenon	NN
cord-022561-rv5j1201	299	6	is	be	VBZ
cord-022561-rv5j1201	299	7	unknown	unknown	JJ
cord-022561-rv5j1201	299	8	,	,	,
cord-022561-rv5j1201	299	9	but	but	CC
cord-022561-rv5j1201	299	10	it	-PRON-	PRP
cord-022561-rv5j1201	299	11	is	be	VBZ
cord-022561-rv5j1201	299	12	characterized	characterize	VBN
cord-022561-rv5j1201	299	13	by	by	IN
cord-022561-rv5j1201	299	14	adipocyte	adipocyte	NN
cord-022561-rv5j1201	299	15	atrophy	atrophy	NN
cord-022561-rv5j1201	299	16	,	,	,
cord-022561-rv5j1201	299	17	hematopoietic	hematopoietic	JJ
cord-022561-rv5j1201	299	18	cell	cell	NN
cord-022561-rv5j1201	299	19	hypoplasia	hypoplasia	NN
cord-022561-rv5j1201	299	20	with	with	IN
cord-022561-rv5j1201	299	21	subsequent	subsequent	JJ
cord-022561-rv5j1201	299	22	cytopenias	cytopenia	NNS
cord-022561-rv5j1201	299	23	,	,	,
cord-022561-rv5j1201	299	24	and	and	CC
cord-022561-rv5j1201	299	25	replacement	replacement	NN
cord-022561-rv5j1201	299	26	of	of	IN
cord-022561-rv5j1201	299	27	the	the	DT
cord-022561-rv5j1201	299	28	marrow	marrow	NN
cord-022561-rv5j1201	299	29	with	with	IN
cord-022561-rv5j1201	299	30	extracellular	extracellular	JJ
cord-022561-rv5j1201	299	31	hyaluronic	hyaluronic	NN
cord-022561-rv5j1201	299	32	acid	acid	NN
cord-022561-rv5j1201	299	33	-	-	HYPH
cord-022561-rv5j1201	299	34	rich	rich	JJ
cord-022561-rv5j1201	299	35	mucopolysaccharides	mucopolysaccharide	NNS
cord-022561-rv5j1201	299	36	.	.	.
cord-022561-rv5j1201	300	1	Positive	positive	JJ
cord-022561-rv5j1201	300	2	Alcian	alcian	JJ
cord-022561-rv5j1201	300	3	blue	blue	JJ
cord-022561-rv5j1201	300	4	staining	staining	NN
cord-022561-rv5j1201	300	5	identifies	identify	VBZ
cord-022561-rv5j1201	300	6	the	the	DT
cord-022561-rv5j1201	300	7	extracellular	extracellular	JJ
cord-022561-rv5j1201	300	8	material	material	NN
cord-022561-rv5j1201	300	9	as	as	IN
cord-022561-rv5j1201	300	10	mucin	mucin	NN
cord-022561-rv5j1201	300	11	.	.	.
cord-022561-rv5j1201	301	1	Marrow	marrow	NN
cord-022561-rv5j1201	301	2	adipocytes	adipocyte	NNS
cord-022561-rv5j1201	301	3	secrete	secrete	VBP
cord-022561-rv5j1201	301	4	adipose	adipose	NN
cord-022561-rv5j1201	301	5	-	-	HYPH
cord-022561-rv5j1201	301	6	derived	derive	VBN
cord-022561-rv5j1201	301	7	hormones	hormone	NNS
cord-022561-rv5j1201	301	8	,	,	,
cord-022561-rv5j1201	301	9	termed	term	VBN
cord-022561-rv5j1201	301	10	adipokines	adipokine	NNS
cord-022561-rv5j1201	301	11	,	,	,
cord-022561-rv5j1201	301	12	including	include	VBG
cord-022561-rv5j1201	301	13	leptin	leptin	NN
cord-022561-rv5j1201	301	14	and	and	CC
cord-022561-rv5j1201	301	15	adiponectin	adiponectin	NN
cord-022561-rv5j1201	301	16	.	.	.
cord-022561-rv5j1201	302	1	In	in	IN
cord-022561-rv5j1201	302	2	general	general	JJ
cord-022561-rv5j1201	302	3	,	,	,
cord-022561-rv5j1201	302	4	leptin	leptin	NN
cord-022561-rv5j1201	302	5	is	be	VBZ
cord-022561-rv5j1201	302	6	proinflammatory	proinflammatory	JJ
cord-022561-rv5j1201	302	7	,	,	,
cord-022561-rv5j1201	302	8	prothrombotic	prothrombotic	JJ
cord-022561-rv5j1201	302	9	,	,	,
cord-022561-rv5j1201	302	10	and	and	CC
cord-022561-rv5j1201	302	11	mitogenic	mitogenic	NNP
cord-022561-rv5j1201	302	12	for	for	IN
cord-022561-rv5j1201	302	13	various	various	JJ
cord-022561-rv5j1201	302	14	cell	cell	NN
cord-022561-rv5j1201	302	15	types	type	NNS
cord-022561-rv5j1201	302	16	,	,	,
cord-022561-rv5j1201	302	17	including	include	VBG
cord-022561-rv5j1201	302	18	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	302	19	,	,	,
cord-022561-rv5j1201	302	20	hematopoietic	hematopoietic	JJ
cord-022561-rv5j1201	302	21	progenitors	progenitor	NNS
cord-022561-rv5j1201	302	22	,	,	,
cord-022561-rv5j1201	302	23	and	and	CC
cord-022561-rv5j1201	302	24	leukemic	leukemic	JJ
cord-022561-rv5j1201	302	25	cells	cell	NNS
cord-022561-rv5j1201	302	26	.	.	.
cord-022561-rv5j1201	303	1	Conversely	conversely	RB
cord-022561-rv5j1201	303	2	,	,	,
cord-022561-rv5j1201	303	3	adiponectin	adiponectin	NN
cord-022561-rv5j1201	303	4	has	have	VBZ
cord-022561-rv5j1201	303	5	antiinflammatory	antiinflammatory	JJ
cord-022561-rv5j1201	303	6	and	and	CC
cord-022561-rv5j1201	303	7	growth	growth	NN
cord-022561-rv5j1201	303	8	inhibitory	inhibitory	JJ
cord-022561-rv5j1201	303	9	properties	property	NNS
cord-022561-rv5j1201	303	10	.	.	.
cord-022561-rv5j1201	304	1	During	during	IN
cord-022561-rv5j1201	304	2	times	time	NNS
cord-022561-rv5j1201	304	3	of	of	IN
cord-022561-rv5j1201	304	4	inflammation	inflammation	NN
cord-022561-rv5j1201	304	5	and	and	CC
cord-022561-rv5j1201	304	6	infection	infection	NN
cord-022561-rv5j1201	304	7	,	,	,
cord-022561-rv5j1201	304	8	leptin	leptin	NN
cord-022561-rv5j1201	304	9	production	production	NN
cord-022561-rv5j1201	304	10	is	be	VBZ
cord-022561-rv5j1201	304	11	increased	increase	VBN
cord-022561-rv5j1201	304	12	.	.	.
cord-022561-rv5j1201	305	1	In	in	IN
cord-022561-rv5j1201	305	2	response	response	NN
cord-022561-rv5j1201	305	3	to	to	IN
cord-022561-rv5j1201	305	4	marrow	marrow	NN
cord-022561-rv5j1201	305	5	trauma	trauma	NN
cord-022561-rv5j1201	305	6	,	,	,
cord-022561-rv5j1201	305	7	such	such	JJ
cord-022561-rv5j1201	305	8	as	as	IN
cord-022561-rv5j1201	305	9	orthopedic	orthopedic	NN
cord-022561-rv5j1201	305	10	surgery	surgery	NN
cord-022561-rv5j1201	305	11	,	,	,
cord-022561-rv5j1201	305	12	fat	fat	JJ
cord-022561-rv5j1201	305	13	may	may	MD
cord-022561-rv5j1201	305	14	enter	enter	VB
cord-022561-rv5j1201	305	15	the	the	DT
cord-022561-rv5j1201	305	16	vasculature	vasculature	NN
cord-022561-rv5j1201	305	17	,	,	,
cord-022561-rv5j1201	305	18	embolize	embolize	NNP
cord-022561-rv5j1201	305	19	to	to	IN
cord-022561-rv5j1201	305	20	various	various	JJ
cord-022561-rv5j1201	305	21	tissues	tissue	NNS
cord-022561-rv5j1201	305	22	,	,	,
cord-022561-rv5j1201	305	23	and	and	CC
cord-022561-rv5j1201	305	24	cause	cause	VB
cord-022561-rv5j1201	305	25	tissue	tissue	NN
cord-022561-rv5j1201	305	26	ischemia	ischemia	NN
cord-022561-rv5j1201	305	27	.	.	.
cord-022561-rv5j1201	306	1	The	the	DT
cord-022561-rv5j1201	306	2	severity	severity	NN
cord-022561-rv5j1201	306	3	of	of	IN
cord-022561-rv5j1201	306	4	tissue	tissue	NN
cord-022561-rv5j1201	306	5	injury	injury	NN
cord-022561-rv5j1201	306	6	caused	cause	VBN
cord-022561-rv5j1201	306	7	by	by	IN
cord-022561-rv5j1201	306	8	fat	fat	JJ
cord-022561-rv5j1201	306	9	embolism	embolism	NN
cord-022561-rv5j1201	306	10	is	be	VBZ
cord-022561-rv5j1201	306	11	dependent	dependent	JJ
cord-022561-rv5j1201	306	12	upon	upon	IN
cord-022561-rv5j1201	306	13	the	the	DT
cord-022561-rv5j1201	306	14	quantity	quantity	NN
cord-022561-rv5j1201	306	15	of	of	IN
cord-022561-rv5j1201	306	16	fat	fat	JJ
cord-022561-rv5j1201	306	17	entering	enter	VBG
cord-022561-rv5j1201	306	18	circulation	circulation	NN
cord-022561-rv5j1201	306	19	and	and	CC
cord-022561-rv5j1201	306	20	the	the	DT
cord-022561-rv5j1201	306	21	tissue	tissue	NN
cord-022561-rv5j1201	306	22	's	's	POS
cord-022561-rv5j1201	306	23	susceptibility	susceptibility	NN
cord-022561-rv5j1201	306	24	to	to	IN
cord-022561-rv5j1201	306	25	ischemia	ischemia	NN
cord-022561-rv5j1201	306	26	(	(	-LRB-
cord-022561-rv5j1201	306	27	see	see	VB
cord-022561-rv5j1201	306	28	Chapter	chapter	NN
cord-022561-rv5j1201	306	29	2	2	CD
cord-022561-rv5j1201	306	30	)	)	-RRB-
cord-022561-rv5j1201	306	31	.	.	.
cord-022561-rv5j1201	307	1	Responses	response	NNS
cord-022561-rv5j1201	307	2	of	of	IN
cord-022561-rv5j1201	307	3	circulating	circulate	VBG
cord-022561-rv5j1201	307	4	blood	blood	NN
cord-022561-rv5j1201	307	5	cells	cell	NNS
cord-022561-rv5j1201	307	6	to	to	IN
cord-022561-rv5j1201	307	7	injury	injury	NN
cord-022561-rv5j1201	307	8	include	include	VBP
cord-022561-rv5j1201	307	9	decreased	decrease	VBN
cord-022561-rv5j1201	307	10	survival	survival	NN
cord-022561-rv5j1201	307	11	(	(	-LRB-
cord-022561-rv5j1201	307	12	destruction	destruction	NN
cord-022561-rv5j1201	307	13	,	,	,
cord-022561-rv5j1201	307	14	consumption	consumption	NN
cord-022561-rv5j1201	307	15	,	,	,
cord-022561-rv5j1201	307	16	or	or	CC
cord-022561-rv5j1201	307	17	loss	loss	NN
cord-022561-rv5j1201	307	18	)	)	-RRB-
cord-022561-rv5j1201	307	19	,	,	,
cord-022561-rv5j1201	307	20	altered	alter	VBN
cord-022561-rv5j1201	307	21	distribution	distribution	NN
cord-022561-rv5j1201	307	22	,	,	,
cord-022561-rv5j1201	307	23	and	and	CC
cord-022561-rv5j1201	307	24	altered	alter	VBN
cord-022561-rv5j1201	307	25	structure	structure	NN
cord-022561-rv5j1201	307	26	or	or	CC
cord-022561-rv5j1201	307	27	function	function	NN
cord-022561-rv5j1201	307	28	(	(	-LRB-
cord-022561-rv5j1201	307	29	see	see	VB
cord-022561-rv5j1201	307	30	Box	Box	NNP
cord-022561-rv5j1201	307	31	13	13	CD
cord-022561-rv5j1201	307	32	-	-	SYM
cord-022561-rv5j1201	307	33	1	1	CD
cord-022561-rv5j1201	307	34	)	)	-RRB-
cord-022561-rv5j1201	307	35	.	.	.
cord-022561-rv5j1201	308	1	These	these	DT
cord-022561-rv5j1201	308	2	responses	response	NNS
cord-022561-rv5j1201	308	3	are	be	VBP
cord-022561-rv5j1201	308	4	not	not	RB
cord-022561-rv5j1201	308	5	mutually	mutually	RB
cord-022561-rv5j1201	308	6	exclusive	exclusive	JJ
cord-022561-rv5j1201	308	7	-	-	HYPH
cord-022561-rv5j1201	308	8	for	for	RP
cord-022561-rv5j1201	308	9	example	example	NN
cord-022561-rv5j1201	308	10	,	,	,
cord-022561-rv5j1201	308	11	altered	altered	JJ
cord-022561-rv5j1201	308	12	erythrocyte	erythrocyte	NN
cord-022561-rv5j1201	308	13	structure	structure	NN
cord-022561-rv5j1201	308	14	may	may	MD
cord-022561-rv5j1201	308	15	lead	lead	VB
cord-022561-rv5j1201	308	16	to	to	IN
cord-022561-rv5j1201	308	17	decreased	decrease	VBN
cord-022561-rv5j1201	308	18	survival	survival	NN
cord-022561-rv5j1201	308	19	.	.	.
cord-022561-rv5j1201	309	1	Often	often	RB
cord-022561-rv5j1201	309	2	,	,	,
cord-022561-rv5j1201	309	3	but	but	CC
cord-022561-rv5j1201	309	4	not	not	RB
cord-022561-rv5j1201	309	5	always	always	RB
cord-022561-rv5j1201	309	6	,	,	,
cord-022561-rv5j1201	309	7	these	these	DT
cord-022561-rv5j1201	309	8	responses	response	NNS
cord-022561-rv5j1201	309	9	result	result	VBP
cord-022561-rv5j1201	309	10	in	in	IN
cord-022561-rv5j1201	309	11	decreased	decreased	JJ
cord-022561-rv5j1201	309	12	concentrations	concentration	NNS
cord-022561-rv5j1201	309	13	of	of	IN
cord-022561-rv5j1201	309	14	blood	blood	NN
cord-022561-rv5j1201	309	15	cells	cell	NNS
cord-022561-rv5j1201	309	16	in	in	IN
cord-022561-rv5j1201	309	17	circulation	circulation	NN
cord-022561-rv5j1201	309	18	.	.	.
cord-022561-rv5j1201	310	1	Abnormal	abnormal	JJ
cord-022561-rv5j1201	310	2	Concentrations	concentration	NNS
cord-022561-rv5j1201	310	3	of	of	IN
cord-022561-rv5j1201	310	4	Blood	blood	NN
cord-022561-rv5j1201	310	5	Cells	cell	NNS
cord-022561-rv5j1201	310	6	.	.	.
cord-022561-rv5j1201	311	1	The	the	DT
cord-022561-rv5j1201	311	2	concentration	concentration	NN
cord-022561-rv5j1201	311	3	of	of	IN
cord-022561-rv5j1201	311	4	blood	blood	NN
cord-022561-rv5j1201	311	5	cells	cell	NNS
cord-022561-rv5j1201	311	6	may	may	MD
cord-022561-rv5j1201	311	7	be	be	VB
cord-022561-rv5j1201	311	8	decreased	decrease	VBN
cord-022561-rv5j1201	311	9	,	,	,
cord-022561-rv5j1201	311	10	termed	term	VBN
cord-022561-rv5j1201	311	11	cytopenia	cytopenia	NNP
cord-022561-rv5j1201	311	12	(	(	-LRB-
cord-022561-rv5j1201	311	13	from	from	IN
cord-022561-rv5j1201	311	14	kytos	kytos	NNP
cord-022561-rv5j1201	311	15	[	[	-LRB-
cord-022561-rv5j1201	311	16	Gr	Gr	NNP
cord-022561-rv5j1201	311	17	.	.	NNP
cord-022561-rv5j1201	311	18	,	,	,
cord-022561-rv5j1201	311	19	hollow	hollow	JJ
cord-022561-rv5j1201	311	20	vessel	vessel	NN
cord-022561-rv5j1201	311	21	]	]	-RRB-
cord-022561-rv5j1201	311	22	and	and	CC
cord-022561-rv5j1201	311	23	penia	penia	NNP
cord-022561-rv5j1201	311	24	[	[	-LRB-
cord-022561-rv5j1201	311	25	Gr	Gr	NNP
cord-022561-rv5j1201	311	26	.	.	NNP
cord-022561-rv5j1201	311	27	,	,	,
cord-022561-rv5j1201	311	28	poverty	poverty	NN
cord-022561-rv5j1201	311	29	]	]	-RRB-
cord-022561-rv5j1201	311	30	)	)	-RRB-
cord-022561-rv5j1201	311	31	or	or	CC
cord-022561-rv5j1201	311	32	increased	increase	VBD
cord-022561-rv5j1201	311	33	,	,	,
cord-022561-rv5j1201	311	34	designated	designate	VBN
cord-022561-rv5j1201	311	35	cytosis	cytosis	NN
cord-022561-rv5j1201	311	36	(	(	-LRB-
cord-022561-rv5j1201	311	37	from	from	IN
cord-022561-rv5j1201	311	38	osis	osis	NN
cord-022561-rv5j1201	311	39	[	[	-LRB-
cord-022561-rv5j1201	311	40	Gr	Gr	NNP
cord-022561-rv5j1201	311	41	.	.	NNP
cord-022561-rv5j1201	311	42	,	,	,
cord-022561-rv5j1201	311	43	condition	condition	NN
cord-022561-rv5j1201	311	44	]	]	-RRB-
cord-022561-rv5j1201	311	45	)	)	-RRB-
cord-022561-rv5j1201	311	46	.	.	.
cord-022561-rv5j1201	312	1	A	a	DT
cord-022561-rv5j1201	312	2	specific	specific	JJ
cord-022561-rv5j1201	312	3	blood	blood	NN
cord-022561-rv5j1201	312	4	cell	cell	NN
cord-022561-rv5j1201	312	5	type	type	NN
cord-022561-rv5j1201	312	6	is	be	VBZ
cord-022561-rv5j1201	312	7	denoted	denote	VBN
cord-022561-rv5j1201	312	8	as	as	IN
cord-022561-rv5j1201	312	9	being	be	VBG
cord-022561-rv5j1201	312	10	decreased	decrease	VBN
cord-022561-rv5j1201	312	11	by	by	IN
cord-022561-rv5j1201	312	12	using	use	VBG
cord-022561-rv5j1201	312	13	the	the	DT
cord-022561-rv5j1201	312	14	suffix	suffix	NN
cord-022561-rv5j1201	312	15	-penia	-penia	NN
cord-022561-rv5j1201	313	1	(	(	-LRB-
cord-022561-rv5j1201	313	2	Table	Table	NNP
cord-022561-rv5j1201	313	3	13	13	CD
cord-022561-rv5j1201	313	4	-	-	SYM
cord-022561-rv5j1201	313	5	1	1	CD
cord-022561-rv5j1201	313	6	)	)	-RRB-
cord-022561-rv5j1201	313	7	.	.	.
cord-022561-rv5j1201	314	1	A	a	DT
cord-022561-rv5j1201	314	2	decreased	decrease	VBN
cord-022561-rv5j1201	314	3	concentration	concentration	NN
cord-022561-rv5j1201	314	4	of	of	IN
cord-022561-rv5j1201	314	5	erythrocytes	erythrocyte	NNS
cord-022561-rv5j1201	314	6	is	be	VBZ
cord-022561-rv5j1201	314	7	the	the	DT
cord-022561-rv5j1201	314	8	exception	exception	NN
cord-022561-rv5j1201	314	9	and	and	CC
cord-022561-rv5j1201	314	10	is	be	VBZ
cord-022561-rv5j1201	314	11	termed	term	VBN
cord-022561-rv5j1201	314	12	anemia	anemia	NN
cord-022561-rv5j1201	314	13	(	(	-LRB-
cord-022561-rv5j1201	314	14	from	from	IN
cord-022561-rv5j1201	314	15	a	a	DT
cord-022561-rv5j1201	314	16	[	[	-LRB-
cord-022561-rv5j1201	314	17	Gr	Gr	NNP
cord-022561-rv5j1201	314	18	.	.	NNP
cord-022561-rv5j1201	314	19	,	,	,
cord-022561-rv5j1201	314	20	without	without	IN
cord-022561-rv5j1201	314	21	]	]	-RRB-
cord-022561-rv5j1201	314	22	and	and	CC
cord-022561-rv5j1201	314	23	haima	haima	NNP
cord-022561-rv5j1201	314	24	[	[	-LRB-
cord-022561-rv5j1201	314	25	Gr	Gr	NNP
cord-022561-rv5j1201	314	26	.	.	NNP
cord-022561-rv5j1201	314	27	,	,	,
cord-022561-rv5j1201	314	28	blood	blood	NN
cord-022561-rv5j1201	314	29	]	]	-RRB-
cord-022561-rv5j1201	314	30	)	)	-RRB-
cord-022561-rv5j1201	314	31	.	.	.
cord-022561-rv5j1201	315	1	Decreased	decrease	VBN
cord-022561-rv5j1201	315	2	concentrations	concentration	NNS
cord-022561-rv5j1201	315	3	of	of	IN
cord-022561-rv5j1201	315	4	blood	blood	NN
cord-022561-rv5j1201	315	5	basophils	basophil	NNS
cord-022561-rv5j1201	315	6	are	be	VBP
cord-022561-rv5j1201	315	7	not	not	RB
cord-022561-rv5j1201	315	8	recognized	recognize	VBN
cord-022561-rv5j1201	315	9	in	in	IN
cord-022561-rv5j1201	315	10	domestic	domestic	JJ
cord-022561-rv5j1201	315	11	animals	animal	NNS
cord-022561-rv5j1201	315	12	because	because	IN
cord-022561-rv5j1201	315	13	the	the	DT
cord-022561-rv5j1201	315	14	lower	low	JJR
cord-022561-rv5j1201	315	15	reference	reference	NN
cord-022561-rv5j1201	315	16	interval	interval	NN
cord-022561-rv5j1201	315	17	is	be	VBZ
cord-022561-rv5j1201	315	18	typically	typically	RB
cord-022561-rv5j1201	315	19	zero	zero	CD
cord-022561-rv5j1201	315	20	.	.	.
cord-022561-rv5j1201	316	1	An	an	DT
cord-022561-rv5j1201	316	2	increased	increase	VBN
cord-022561-rv5j1201	316	3	blood	blood	NN
cord-022561-rv5j1201	316	4	cell	cell	NN
cord-022561-rv5j1201	316	5	type	type	NN
cord-022561-rv5j1201	316	6	is	be	VBZ
cord-022561-rv5j1201	316	7	denoted	denote	VBN
cord-022561-rv5j1201	316	8	with	with	IN
cord-022561-rv5j1201	316	9	the	the	DT
cord-022561-rv5j1201	316	10	suffix	suffix	NN
cord-022561-rv5j1201	316	11	-osis	-osis	NN
cord-022561-rv5j1201	316	12	or	or	CC
cord-022561-rv5j1201	316	13	-philia	-philia	NN
cord-022561-rv5j1201	317	1	(	(	-LRB-
cord-022561-rv5j1201	317	2	see	see	VB
cord-022561-rv5j1201	317	3	Table	Table	NNP
cord-022561-rv5j1201	317	4	13	13	CD
cord-022561-rv5j1201	317	5	-1	-1	NN
cord-022561-rv5j1201	317	6	)	)	-RRB-
cord-022561-rv5j1201	317	7	.	.	.
cord-022561-rv5j1201	318	1	Postmortem	postmortem	JJ
cord-022561-rv5j1201	318	2	quantification	quantification	NN
cord-022561-rv5j1201	318	3	of	of	IN
cord-022561-rv5j1201	318	4	blood	blood	NN
cord-022561-rv5j1201	318	5	cell	cell	NN
cord-022561-rv5j1201	318	6	Insults	insult	NNS
cord-022561-rv5j1201	318	7	to	to	IN
cord-022561-rv5j1201	318	8	extramarrow	extramarrow	NN
cord-022561-rv5j1201	318	9	tissues	tissue	NNS
cord-022561-rv5j1201	318	10	and	and	CC
cord-022561-rv5j1201	318	11	cells	cell	NNS
cord-022561-rv5j1201	318	12	tend	tend	VBP
cord-022561-rv5j1201	318	13	to	to	TO
cord-022561-rv5j1201	318	14	cause	cause	VB
cord-022561-rv5j1201	318	15	increased	increase	VBN
cord-022561-rv5j1201	318	16	production	production	NN
cord-022561-rv5j1201	318	17	of	of	IN
cord-022561-rv5j1201	318	18	the	the	DT
cord-022561-rv5j1201	318	19	involved	involved	JJ
cord-022561-rv5j1201	318	20	cell	cell	NN
cord-022561-rv5j1201	318	21	types	type	NNS
cord-022561-rv5j1201	318	22	(	(	-LRB-
cord-022561-rv5j1201	318	23	hyperplasia	hyperplasia	NN
cord-022561-rv5j1201	318	24	)	)	-RRB-
cord-022561-rv5j1201	318	25	with	with	IN
cord-022561-rv5j1201	318	26	or	or	CC
cord-022561-rv5j1201	318	27	without	without	IN
cord-022561-rv5j1201	318	28	dysplasia	dysplasia	NN
cord-022561-rv5j1201	318	29	.	.	.
cord-022561-rv5j1201	319	1	Loss	loss	NN
cord-022561-rv5j1201	319	2	of	of	IN
cord-022561-rv5j1201	319	3	erythrocytes	erythrocyte	NNS
cord-022561-rv5j1201	319	4	from	from	IN
cord-022561-rv5j1201	319	5	blood	blood	NN
cord-022561-rv5j1201	319	6	vessels	vessel	NNS
cord-022561-rv5j1201	319	7	(	(	-LRB-
cord-022561-rv5j1201	319	8	hemorrhage	hemorrhage	NN
cord-022561-rv5j1201	319	9	)	)	-RRB-
cord-022561-rv5j1201	319	10	,	,	,
cord-022561-rv5j1201	319	11	or	or	CC
cord-022561-rv5j1201	319	12	premature	premature	JJ
cord-022561-rv5j1201	319	13	destruction	destruction	NN
cord-022561-rv5j1201	319	14	of	of	IN
cord-022561-rv5j1201	319	15	erythrocytes	erythrocyte	NNS
cord-022561-rv5j1201	319	16	(	(	-LRB-
cord-022561-rv5j1201	319	17	hemolysis	hemolysis	NN
cord-022561-rv5j1201	319	18	)	)	-RRB-
cord-022561-rv5j1201	319	19	causes	cause	VBZ
cord-022561-rv5j1201	319	20	erythroid	erythroid	JJ
cord-022561-rv5j1201	319	21	hyperplasia	hyperplasia	NN
cord-022561-rv5j1201	319	22	.	.	.
cord-022561-rv5j1201	320	1	Tissue	tissue	NN
cord-022561-rv5j1201	320	2	inflammation	inflammation	NN
cord-022561-rv5j1201	320	3	may	may	MD
cord-022561-rv5j1201	320	4	cause	cause	VB
cord-022561-rv5j1201	320	5	neutrophilic	neutrophilic	NNP
cord-022561-rv5j1201	320	6	,	,	,
cord-022561-rv5j1201	320	7	eosinophilic	eosinophilic	JJ
cord-022561-rv5j1201	320	8	,	,	,
cord-022561-rv5j1201	320	9	basophilic	basophilic	NNP
cord-022561-rv5j1201	320	10	,	,	,
cord-022561-rv5j1201	320	11	and/or	and/or	CC
cord-022561-rv5j1201	320	12	monocytic	monocytic	JJ
cord-022561-rv5j1201	320	13	hyperplasia	hyperplasia	NN
cord-022561-rv5j1201	320	14	,	,	,
cord-022561-rv5j1201	320	15	depending	depend	VBG
cord-022561-rv5j1201	320	16	on	on	IN
cord-022561-rv5j1201	320	17	the	the	DT
cord-022561-rv5j1201	320	18	type	type	NN
cord-022561-rv5j1201	320	19	of	of	IN
cord-022561-rv5j1201	320	20	inflammation	inflammation	NN
cord-022561-rv5j1201	320	21	.	.	.
cord-022561-rv5j1201	321	1	Megakaryocytic	megakaryocytic	JJ
cord-022561-rv5j1201	321	2	hyperplasia	hyperplasia	NN
cord-022561-rv5j1201	321	3	may	may	MD
cord-022561-rv5j1201	321	4	occur	occur	VB
cord-022561-rv5j1201	321	5	with	with	IN
cord-022561-rv5j1201	321	6	increased	increase	VBN
cord-022561-rv5j1201	321	7	platelet	platelet	NN
cord-022561-rv5j1201	321	8	use	use	NN
cord-022561-rv5j1201	321	9	during	during	IN
cord-022561-rv5j1201	321	10	hemorrhage	hemorrhage	NN
cord-022561-rv5j1201	321	11	or	or	CC
cord-022561-rv5j1201	321	12	disseminated	disseminate	VBN
cord-022561-rv5j1201	321	13	intravascular	intravascular	JJ
cord-022561-rv5j1201	321	14	coagulation	coagulation	NN
cord-022561-rv5j1201	321	15	(	(	-LRB-
cord-022561-rv5j1201	321	16	DIC	DIC	NNP
cord-022561-rv5j1201	321	17	)	)	-RRB-
cord-022561-rv5j1201	321	18	or	or	CC
cord-022561-rv5j1201	321	19	with	with	IN
cord-022561-rv5j1201	321	20	immune	immune	NN
cord-022561-rv5j1201	321	21	-	-	HYPH
cord-022561-rv5j1201	321	22	mediated	mediate	VBN
cord-022561-rv5j1201	321	23	platelet	platelet	NN
cord-022561-rv5j1201	321	24	destruction	destruction	NN
cord-022561-rv5j1201	321	25	.	.	.
cord-022561-rv5j1201	322	1	Exceptions	exception	NNS
cord-022561-rv5j1201	322	2	to	to	IN
cord-022561-rv5j1201	322	3	these	these	DT
cord-022561-rv5j1201	322	4	generalizations	generalization	NNS
cord-022561-rv5j1201	322	5	,	,	,
cord-022561-rv5j1201	322	6	such	such	JJ
cord-022561-rv5j1201	322	7	as	as	IN
cord-022561-rv5j1201	322	8	anemia	anemia	NN
cord-022561-rv5j1201	322	9	of	of	IN
cord-022561-rv5j1201	322	10	chronic	chronic	JJ
cord-022561-rv5j1201	322	11	disease	disease	NN
cord-022561-rv5j1201	322	12	,	,	,
cord-022561-rv5j1201	322	13	iron	iron	NN
cord-022561-rv5j1201	322	14	deficiency	deficiency	NN
cord-022561-rv5j1201	322	15	anemia	anemia	NN
cord-022561-rv5j1201	322	16	,	,	,
cord-022561-rv5j1201	322	17	and	and	CC
cord-022561-rv5j1201	322	18	anemia	anemia	NN
cord-022561-rv5j1201	322	19	of	of	IN
cord-022561-rv5j1201	322	20	renal	renal	JJ
cord-022561-rv5j1201	322	21	failure	failure	NN
cord-022561-rv5j1201	322	22	,	,	,
cord-022561-rv5j1201	322	23	are	be	VBP
cord-022561-rv5j1201	322	24	discussed	discuss	VBN
cord-022561-rv5j1201	322	25	in	in	IN
cord-022561-rv5j1201	322	26	more	more	JJR
cord-022561-rv5j1201	322	27	detail	detail	NN
cord-022561-rv5j1201	322	28	later	later	RB
cord-022561-rv5j1201	322	29	.	.	.
cord-022561-rv5j1201	323	1	Endothelial	endothelial	JJ
cord-022561-rv5j1201	323	2	cell	cell	NN
cord-022561-rv5j1201	323	3	response	response	NN
cord-022561-rv5j1201	323	4	to	to	IN
cord-022561-rv5j1201	323	5	injury	injury	NN
cord-022561-rv5j1201	323	6	specifically	specifically	RB
cord-022561-rv5j1201	323	7	within	within	IN
cord-022561-rv5j1201	323	8	the	the	DT
cord-022561-rv5j1201	323	9	marrow	marrow	NN
cord-022561-rv5j1201	323	10	is	be	VBZ
cord-022561-rv5j1201	323	11	poorly	poorly	RB
cord-022561-rv5j1201	323	12	characterized	characterize	VBN
cord-022561-rv5j1201	323	13	,	,	,
cord-022561-rv5j1201	323	14	but	but	CC
cord-022561-rv5j1201	323	15	it	-PRON-	PRP
cord-022561-rv5j1201	323	16	is	be	VBZ
cord-022561-rv5j1201	323	17	likely	likely	RB
cord-022561-rv5j1201	323	18	similar	similar	JJ
cord-022561-rv5j1201	323	19	to	to	IN
cord-022561-rv5j1201	323	20	that	that	DT
cord-022561-rv5j1201	323	21	of	of	IN
cord-022561-rv5j1201	323	22	endothelial	endothelial	JJ
cord-022561-rv5j1201	323	23	cells	cell	NNS
cord-022561-rv5j1201	323	24	elsewhere	elsewhere	RB
cord-022561-rv5j1201	323	25	,	,	,
cord-022561-rv5j1201	323	26	playing	play	VBG
cord-022561-rv5j1201	323	27	active	active	JJ
cord-022561-rv5j1201	323	28	roles	role	NNS
cord-022561-rv5j1201	323	29	in	in	IN
cord-022561-rv5j1201	323	30	coagulation	coagulation	NN
cord-022561-rv5j1201	323	31	and	and	CC
cord-022561-rv5j1201	323	32	inflammation	inflammation	NN
cord-022561-rv5j1201	323	33	(	(	-LRB-
cord-022561-rv5j1201	323	34	see	see	VB
cord-022561-rv5j1201	323	35	Chapters	chapter	NNS
cord-022561-rv5j1201	323	36	2	2	CD
cord-022561-rv5j1201	323	37	and	and	CC
cord-022561-rv5j1201	323	38	3	3	CD
cord-022561-rv5j1201	323	39	)	)	-RRB-
cord-022561-rv5j1201	323	40	.	.	.
cord-022561-rv5j1201	324	1	However	however	RB
cord-022561-rv5j1201	324	2	,	,	,
cord-022561-rv5j1201	324	3	one	one	CD
cord-022561-rv5j1201	324	4	potential	potential	JJ
cord-022561-rv5j1201	324	5	sign	sign	NN
cord-022561-rv5j1201	324	6	of	of	IN
cord-022561-rv5j1201	324	7	marrow	marrow	NN
cord-022561-rv5j1201	324	8	sinusoidal	sinusoidal	JJ
cord-022561-rv5j1201	324	9	injury	injury	NN
cord-022561-rv5j1201	324	10	is	be	VBZ
cord-022561-rv5j1201	324	11	the	the	DT
cord-022561-rv5j1201	324	12	presence	presence	NN
cord-022561-rv5j1201	324	13	of	of	IN
cord-022561-rv5j1201	324	14	circulating	circulate	VBG
cord-022561-rv5j1201	324	15	nucleated	nucleated	JJ
cord-022561-rv5j1201	324	16	erythrocytes	erythrocyte	NNS
cord-022561-rv5j1201	324	17	in	in	IN
cord-022561-rv5j1201	324	18	the	the	DT
cord-022561-rv5j1201	324	19	absence	absence	NN
cord-022561-rv5j1201	324	20	of	of	IN
cord-022561-rv5j1201	324	21	erythrocyte	erythrocyte	NN
cord-022561-rv5j1201	324	22	regeneration	regeneration	NN
cord-022561-rv5j1201	324	23	,	,	,
cord-022561-rv5j1201	324	24	termed	term	VBD
cord-022561-rv5j1201	324	25	inappropriate	inappropriate	JJ
cord-022561-rv5j1201	324	26	metarubricytosis	metarubricytosis	NN
cord-022561-rv5j1201	324	27	.	.	.
cord-022561-rv5j1201	325	1	It	-PRON-	PRP
cord-022561-rv5j1201	325	2	is	be	VBZ
cord-022561-rv5j1201	325	3	proposed	propose	VBN
cord-022561-rv5j1201	325	4	that	that	IN
cord-022561-rv5j1201	325	5	injured	injure	VBN
cord-022561-rv5j1201	325	6	marrow	marrow	NN
cord-022561-rv5j1201	325	7	endothelial	endothelial	NN
cord-022561-rv5j1201	325	8	cells	cell	NNS
cord-022561-rv5j1201	325	9	allow	allow	VBP
cord-022561-rv5j1201	325	10	premature	premature	JJ
cord-022561-rv5j1201	325	11	passage	passage	NN
cord-022561-rv5j1201	325	12	of	of	IN
cord-022561-rv5j1201	325	13	metarubricytes	metarubricyte	NNS
cord-022561-rv5j1201	325	14	into	into	IN
cord-022561-rv5j1201	325	15	blood	blood	NN
cord-022561-rv5j1201	325	16	circulation	circulation	NN
cord-022561-rv5j1201	325	17	during	during	IN
cord-022561-rv5j1201	325	18	times	time	NNS
cord-022561-rv5j1201	325	19	of	of	IN
cord-022561-rv5j1201	325	20	stress	stress	NN
cord-022561-rv5j1201	325	21	.	.	.
cord-022561-rv5j1201	326	1	However	however	RB
cord-022561-rv5j1201	326	2	,	,	,
cord-022561-rv5j1201	326	3	a	a	DT
cord-022561-rv5j1201	326	4	conflicting	conflict	VBG
cord-022561-rv5j1201	326	5	theory	theory	NN
cord-022561-rv5j1201	326	6	proposes	propose	VBZ
cord-022561-rv5j1201	326	7	that	that	IN
cord-022561-rv5j1201	326	8	marrow	marrow	NN
cord-022561-rv5j1201	326	9	stress	stress	NN
cord-022561-rv5j1201	326	10	causes	cause	NNS
cord-022561-rv5j1201	326	11	decreased	decrease	VBD
cord-022561-rv5j1201	326	12	metarubricyte	metarubricyte	NN
cord-022561-rv5j1201	326	13	attachment	attachment	NN
cord-022561-rv5j1201	326	14	to	to	IN
cord-022561-rv5j1201	326	15	central	central	JJ
cord-022561-rv5j1201	326	16	macrophages	macrophage	NNS
cord-022561-rv5j1201	326	17	,	,	,
cord-022561-rv5j1201	326	18	and	and	CC
cord-022561-rv5j1201	326	19	subsequent	subsequent	JJ
cord-022561-rv5j1201	326	20	release	release	NN
cord-022561-rv5j1201	326	21	into	into	IN
cord-022561-rv5j1201	326	22	circulation	circulation	NN
cord-022561-rv5j1201	326	23	.	.	.
cord-022561-rv5j1201	327	1	Specific	specific	JJ
cord-022561-rv5j1201	327	2	causes	cause	NNS
cord-022561-rv5j1201	327	3	of	of	IN
cord-022561-rv5j1201	327	4	marrow	marrow	NN
cord-022561-rv5j1201	327	5	injury	injury	NN
cord-022561-rv5j1201	327	6	-	-	HYPH
cord-022561-rv5j1201	327	7	induced	induce	VBN
cord-022561-rv5j1201	327	8	metarubricytosis	metarubricytosis	NN
cord-022561-rv5j1201	327	9	include	include	VBP
cord-022561-rv5j1201	327	10	sepsis	sepsis	NN
cord-022561-rv5j1201	327	11	,	,	,
cord-022561-rv5j1201	327	12	hyperthermia	hyperthermia	NN
cord-022561-rv5j1201	327	13	,	,	,
cord-022561-rv5j1201	327	14	malignancies	malignancy	NNS
cord-022561-rv5j1201	327	15	,	,	,
cord-022561-rv5j1201	327	16	hypoxia	hypoxia	NN
cord-022561-rv5j1201	327	17	,	,	,
cord-022561-rv5j1201	327	18	and	and	CC
cord-022561-rv5j1201	327	19	certain	certain	JJ
cord-022561-rv5j1201	327	20	drugs	drug	NNS
cord-022561-rv5j1201	327	21	and	and	CC
cord-022561-rv5j1201	327	22	toxins	toxin	NNS
cord-022561-rv5j1201	327	23	.	.	.
cord-022561-rv5j1201	328	1	Inappropriate	inappropriate	JJ
cord-022561-rv5j1201	328	2	metarubricytosis	metarubricytosis	NN
cord-022561-rv5j1201	328	3	may	may	MD
cord-022561-rv5j1201	328	4	also	also	RB
cord-022561-rv5j1201	328	5	occur	occur	VB
cord-022561-rv5j1201	328	6	with	with	IN
cord-022561-rv5j1201	328	7	erythroid	erythroid	NN
cord-022561-rv5j1201	328	8	dysplasia	dysplasia	NN
cord-022561-rv5j1201	328	9	and	and	CC
cord-022561-rv5j1201	328	10	splenic	splenic	JJ
cord-022561-rv5j1201	328	11	disorders	disorder	NNS
cord-022561-rv5j1201	328	12	.	.	.
cord-022561-rv5j1201	329	1	In	in	IN
cord-022561-rv5j1201	329	2	addition	addition	NN
cord-022561-rv5j1201	329	3	to	to	IN
cord-022561-rv5j1201	329	4	a	a	DT
cord-022561-rv5j1201	329	5	suspected	suspect	VBN
cord-022561-rv5j1201	329	6	role	role	NN
cord-022561-rv5j1201	329	7	in	in	IN
cord-022561-rv5j1201	329	8	inappropriate	inappropriate	JJ
cord-022561-rv5j1201	329	9	metarubricytosis	metarubricytosis	NN
cord-022561-rv5j1201	329	10	,	,	,
cord-022561-rv5j1201	329	11	marrow	marrow	NN
cord-022561-rv5j1201	329	12	macrophages	macrophage	NNS
cord-022561-rv5j1201	329	13	are	be	VBP
cord-022561-rv5j1201	329	14	integral	integral	JJ
cord-022561-rv5j1201	329	15	to	to	IN
cord-022561-rv5j1201	329	16	altered	alter	VBN
cord-022561-rv5j1201	329	17	iron	iron	NN
cord-022561-rv5j1201	329	18	metabolism	metabolism	NN
cord-022561-rv5j1201	329	19	,	,	,
cord-022561-rv5j1201	329	20	including	include	VBG
cord-022561-rv5j1201	329	21	anemia	anemia	NN
cord-022561-rv5j1201	329	22	of	of	IN
cord-022561-rv5j1201	329	23	chronic	chronic	JJ
cord-022561-rv5j1201	329	24	disease	disease	NN
cord-022561-rv5j1201	329	25	and	and	CC
cord-022561-rv5j1201	329	26	hemosiderosis	hemosiderosis	NN
cord-022561-rv5j1201	329	27	.	.	.
cord-022561-rv5j1201	330	1	Anemia	anemia	NN
cord-022561-rv5j1201	330	2	of	of	IN
cord-022561-rv5j1201	330	3	chronic	chronic	JJ
cord-022561-rv5j1201	330	4	disease	disease	NN
cord-022561-rv5j1201	330	5	is	be	VBZ
cord-022561-rv5j1201	330	6	a	a	DT
cord-022561-rv5j1201	330	7	mild	mild	JJ
cord-022561-rv5j1201	330	8	to	to	TO
cord-022561-rv5j1201	330	9	moderate	moderate	JJ
cord-022561-rv5j1201	330	10	nonregenerative	nonregenerative	JJ
cord-022561-rv5j1201	330	11	anemia	anemia	NN
cord-022561-rv5j1201	330	12	observed	observe	VBN
cord-022561-rv5j1201	330	13	in	in	IN
cord-022561-rv5j1201	330	14	animals	animal	NNS
cord-022561-rv5j1201	330	15	with	with	IN
cord-022561-rv5j1201	330	16	a	a	DT
cord-022561-rv5j1201	330	17	variety	variety	NN
cord-022561-rv5j1201	330	18	of	of	IN
cord-022561-rv5j1201	330	19	inflammatory	inflammatory	JJ
cord-022561-rv5j1201	330	20	and	and	CC
cord-022561-rv5j1201	330	21	metabolic	metabolic	JJ
cord-022561-rv5j1201	330	22	disorders	disorder	NNS
cord-022561-rv5j1201	330	23	.	.	.
cord-022561-rv5j1201	331	1	This	this	DT
cord-022561-rv5j1201	331	2	anemia	anemia	NN
cord-022561-rv5j1201	331	3	is	be	VBZ
cord-022561-rv5j1201	331	4	discussed	discuss	VBN
cord-022561-rv5j1201	331	5	in	in	IN
cord-022561-rv5j1201	331	6	more	more	JJR
cord-022561-rv5j1201	331	7	detail	detail	NN
cord-022561-rv5j1201	331	8	later	later	RB
cord-022561-rv5j1201	331	9	,	,	,
cord-022561-rv5j1201	331	10	but	but	CC
cord-022561-rv5j1201	331	11	briefly	briefly	RB
cord-022561-rv5j1201	331	12	,	,	,
cord-022561-rv5j1201	331	13	it	-PRON-	PRP
cord-022561-rv5j1201	331	14	is	be	VBZ
cord-022561-rv5j1201	331	15	primarily	primarily	RB
cord-022561-rv5j1201	331	16	a	a	DT
cord-022561-rv5j1201	331	17	result	result	NN
cord-022561-rv5j1201	331	18	of	of	IN
cord-022561-rv5j1201	331	19	iron	iron	NN
cord-022561-rv5j1201	331	20	sequestration	sequestration	NN
cord-022561-rv5j1201	331	21	within	within	IN
cord-022561-rv5j1201	331	22	macrophages	macrophage	NNS
cord-022561-rv5j1201	331	23	.	.	.
cord-022561-rv5j1201	332	1	Hemosiderosis	Hemosiderosis	NNP
cord-022561-rv5j1201	332	2	is	be	VBZ
cord-022561-rv5j1201	332	3	the	the	DT
cord-022561-rv5j1201	332	4	excessive	excessive	JJ
cord-022561-rv5j1201	332	5	accumulation	accumulation	NN
cord-022561-rv5j1201	332	6	of	of	IN
cord-022561-rv5j1201	332	7	iron	iron	NN
cord-022561-rv5j1201	332	8	in	in	IN
cord-022561-rv5j1201	332	9	tissues	tissue	NNS
cord-022561-rv5j1201	332	10	,	,	,
cord-022561-rv5j1201	332	11	typically	typically	RB
cord-022561-rv5j1201	332	12	macrophages	macrophage	NNS
cord-022561-rv5j1201	332	13	.	.	.
cord-022561-rv5j1201	333	1	Accumulation	accumulation	NN
cord-022561-rv5j1201	333	2	of	of	IN
cord-022561-rv5j1201	333	3	iron	iron	NN
cord-022561-rv5j1201	333	4	in	in	IN
cord-022561-rv5j1201	333	5	parenchymal	parenchymal	JJ
cord-022561-rv5j1201	333	6	organs	organ	NNS
cord-022561-rv5j1201	333	7	,	,	,
cord-022561-rv5j1201	333	8	leading	lead	VBG
cord-022561-rv5j1201	333	9	to	to	IN
cord-022561-rv5j1201	333	10	organ	organ	NN
cord-022561-rv5j1201	333	11	toxicity	toxicity	NN
cord-022561-rv5j1201	333	12	,	,	,
cord-022561-rv5j1201	333	13	is	be	VBZ
cord-022561-rv5j1201	333	14	termed	term	VBN
cord-022561-rv5j1201	333	15	hemochromatosis	hemochromatosis	NN
cord-022561-rv5j1201	333	16	.	.	.
cord-022561-rv5j1201	334	1	In	in	IN
cord-022561-rv5j1201	334	2	animals	animal	NNS
cord-022561-rv5j1201	334	3	,	,	,
cord-022561-rv5j1201	334	4	iron	iron	NN
cord-022561-rv5j1201	334	5	overload	overload	NN
cord-022561-rv5j1201	334	6	due	due	IN
cord-022561-rv5j1201	334	7	to	to	IN
cord-022561-rv5j1201	334	8	blood	blood	NN
cord-022561-rv5j1201	334	9	transfusions	transfusion	NNS
cord-022561-rv5j1201	334	10	or	or	CC
cord-022561-rv5j1201	334	11	chronic	chronic	JJ
cord-022561-rv5j1201	334	12	hemolytic	hemolytic	JJ
cord-022561-rv5j1201	334	13	anemias	anemia	NNS
cord-022561-rv5j1201	334	14	may	may	MD
cord-022561-rv5j1201	334	15	cause	cause	VB
cord-022561-rv5j1201	334	16	marrow	marrow	NN
cord-022561-rv5j1201	334	17	hemosiderosis	hemosiderosis	NN
cord-022561-rv5j1201	334	18	and	and	CC
cord-022561-rv5j1201	334	19	hemochromatosis	hemochromatosis	NN
cord-022561-rv5j1201	334	20	.	.	.
cord-022561-rv5j1201	335	1	Myelitis	Myelitis	NNP
cord-022561-rv5j1201	335	2	can	can	MD
cord-022561-rv5j1201	335	3	take	take	VB
cord-022561-rv5j1201	335	4	different	different	JJ
cord-022561-rv5j1201	335	5	forms	form	NNS
cord-022561-rv5j1201	335	6	.	.	.
cord-022561-rv5j1201	336	1	Granulomatous	granulomatous	JJ
cord-022561-rv5j1201	336	2	myelitis	myelitis	NN
cord-022561-rv5j1201	336	3	occurs	occur	VBZ
cord-022561-rv5j1201	336	4	with	with	IN
cord-022561-rv5j1201	336	5	systemic	systemic	JJ
cord-022561-rv5j1201	336	6	fungal	fungal	JJ
cord-022561-rv5j1201	336	7	infections	infection	NNS
cord-022561-rv5j1201	336	8	(	(	-LRB-
cord-022561-rv5j1201	336	9	e.g.	e.g.	RB
cord-022561-rv5j1201	336	10	,	,	,
cord-022561-rv5j1201	336	11	histoplasmosis	histoplasmosis	NN
cord-022561-rv5j1201	336	12	)	)	-RRB-
cord-022561-rv5j1201	336	13	or	or	CC
cord-022561-rv5j1201	336	14	mycobacteriosis	mycobacteriosis	NNP
cord-022561-rv5j1201	336	15	.	.	.
cord-022561-rv5j1201	337	1	Acute	acute	JJ
cord-022561-rv5j1201	337	2	or	or	CC
cord-022561-rv5j1201	337	3	neutrophilic	neutrophilic	NNP
cord-022561-rv5j1201	337	4	myelitis	myelitis	NNP
cord-022561-rv5j1201	337	5	may	may	MD
cord-022561-rv5j1201	337	6	occur	occur	VB
cord-022561-rv5j1201	337	7	with	with	IN
cord-022561-rv5j1201	337	8	lower	low	JJR
cord-022561-rv5j1201	337	9	-	-	HYPH
cord-022561-rv5j1201	337	10	order	order	NN
cord-022561-rv5j1201	337	11	bacterial	bacterial	JJ
cord-022561-rv5j1201	337	12	infections	infection	NNS
cord-022561-rv5j1201	337	13	or	or	CC
cord-022561-rv5j1201	337	14	those	those	DT
cord-022561-rv5j1201	337	15	with	with	IN
cord-022561-rv5j1201	337	16	an	an	DT
cord-022561-rv5j1201	337	17	immune	immune	NN
cord-022561-rv5j1201	337	18	-	-	HYPH
cord-022561-rv5j1201	337	19	mediated	mediate	VBN
cord-022561-rv5j1201	337	20	component	component	NN
cord-022561-rv5j1201	337	21	.	.	.
cord-022561-rv5j1201	338	1	Dogs	dog	NNS
cord-022561-rv5j1201	338	2	and	and	CC
cord-022561-rv5j1201	338	3	cats	cat	NNS
cord-022561-rv5j1201	338	4	with	with	IN
cord-022561-rv5j1201	338	5	nonregenerative	nonregenerative	JJ
cord-022561-rv5j1201	338	6	immune	immune	NN
cord-022561-rv5j1201	338	7	-	-	HYPH
cord-022561-rv5j1201	338	8	mediated	mediate	VBN
cord-022561-rv5j1201	338	9	hemolytic	hemolytic	JJ
cord-022561-rv5j1201	338	10	anemia	anemia	NN
cord-022561-rv5j1201	338	11	(	(	-LRB-
cord-022561-rv5j1201	338	12	IMHA	IMHA	NNP
cord-022561-rv5j1201	338	13	)	)	-RRB-
cord-022561-rv5j1201	338	14	often	often	RB
cord-022561-rv5j1201	338	15	have	have	VBP
cord-022561-rv5j1201	338	16	myelitis	myelitis	NN
cord-022561-rv5j1201	338	17	,	,	,
cord-022561-rv5j1201	338	18	in	in	IN
cord-022561-rv5j1201	338	19	addition	addition	NN
cord-022561-rv5j1201	338	20	to	to	IN
cord-022561-rv5j1201	338	21	myelofibrosis	myelofibrosis	NNP
cord-022561-rv5j1201	338	22	and	and	CC
cord-022561-rv5j1201	338	23	necrosis	necrosis	NN
cord-022561-rv5j1201	338	24	.	.	.
cord-022561-rv5j1201	339	1	The	the	DT
cord-022561-rv5j1201	339	2	inflammation	inflammation	NN
cord-022561-rv5j1201	339	3	is	be	VBZ
cord-022561-rv5j1201	339	4	evident	evident	JJ
cord-022561-rv5j1201	339	5	as	as	IN
cord-022561-rv5j1201	339	6	fibrin	fibrin	NN
cord-022561-rv5j1201	339	7	deposition	deposition	NN
cord-022561-rv5j1201	339	8	,	,	,
cord-022561-rv5j1201	339	9	edema	edema	NN
cord-022561-rv5j1201	339	10	,	,	,
cord-022561-rv5j1201	339	11	and	and	CC
cord-022561-rv5j1201	339	12	multifocal	multifocal	JJ
cord-022561-rv5j1201	339	13	neutrophilic	neutrophilic	NN
cord-022561-rv5j1201	339	14	infiltrates	infiltrate	VBZ
cord-022561-rv5j1201	339	15	;	;	:
cord-022561-rv5j1201	339	16	immune	immune	JJ
cord-022561-rv5j1201	339	17	-	-	HYPH
cord-022561-rv5j1201	339	18	mediated	mediate	VBN
cord-022561-rv5j1201	339	19	cytopenias	cytopenia	NNS
cord-022561-rv5j1201	339	20	may	may	MD
cord-022561-rv5j1201	339	21	also	also	RB
cord-022561-rv5j1201	339	22	concurrently	concurrently	RB
cord-022561-rv5j1201	339	23	occur	occur	VB
cord-022561-rv5j1201	339	24	with	with	IN
cord-022561-rv5j1201	339	25	bone	bone	NN
cord-022561-rv5j1201	339	26	marrow	marrow	NN
cord-022561-rv5j1201	339	27	lymphocytic	lymphocytic	JJ
cord-022561-rv5j1201	339	28	and/or	and/or	CC
cord-022561-rv5j1201	339	29	plasma	plasma	NN
cord-022561-rv5j1201	339	30	cell	cell	NN
cord-022561-rv5j1201	339	31	hyperplasia	hyperplasia	NN
cord-022561-rv5j1201	339	32	.	.	.
cord-022561-rv5j1201	340	1	Bone	bone	NN
cord-022561-rv5j1201	340	2	marrow	marrow	NN
cord-022561-rv5j1201	340	3	necrosis	necrosis	NN
cord-022561-rv5j1201	340	4	is	be	VBZ
cord-022561-rv5j1201	340	5	the	the	DT
cord-022561-rv5j1201	340	6	necrosis	necrosis	NN
cord-022561-rv5j1201	340	7	of	of	IN
cord-022561-rv5j1201	340	8	medullary	medullary	JJ
cord-022561-rv5j1201	340	9	hematopoietic	hematopoietic	JJ
cord-022561-rv5j1201	340	10	cells	cell	NNS
cord-022561-rv5j1201	340	11	,	,	,
cord-022561-rv5j1201	340	12	stromal	stromal	JJ
cord-022561-rv5j1201	340	13	cells	cell	NNS
cord-022561-rv5j1201	340	14	,	,	,
cord-022561-rv5j1201	340	15	and	and	CC
cord-022561-rv5j1201	340	16	stroma	stroma	NN
cord-022561-rv5j1201	340	17	in	in	IN
cord-022561-rv5j1201	340	18	large	large	JJ
cord-022561-rv5j1201	340	19	areas	area	NNS
cord-022561-rv5j1201	340	20	of	of	IN
cord-022561-rv5j1201	340	21	bone	bone	NN
cord-022561-rv5j1201	340	22	marrow	marrow	NN
cord-022561-rv5j1201	340	23	.	.	.
cord-022561-rv5j1201	341	1	Potential	potential	JJ
cord-022561-rv5j1201	341	2	causes	cause	NNS
cord-022561-rv5j1201	341	3	include	include	VBP
cord-022561-rv5j1201	341	4	leukemias	leukemia	NNS
cord-022561-rv5j1201	341	5	,	,	,
cord-022561-rv5j1201	341	6	extramarrow	extramarrow	NN
cord-022561-rv5j1201	341	7	malignancies	malignancy	NNS
cord-022561-rv5j1201	341	8	,	,	,
cord-022561-rv5j1201	341	9	infection	infection	NN
cord-022561-rv5j1201	341	10	(	(	-LRB-
cord-022561-rv5j1201	341	11	bovine	bovine	JJ
cord-022561-rv5j1201	341	12	viral	viral	JJ
cord-022561-rv5j1201	341	13	diarrhea	diarrhea	NN
cord-022561-rv5j1201	341	14	virus	virus	NN
cord-022561-rv5j1201	341	15	[	[	-LRB-
cord-022561-rv5j1201	341	16	BVDV	BVDV	NNP
cord-022561-rv5j1201	341	17	]	]	-RRB-
cord-022561-rv5j1201	341	18	,	,	,
cord-022561-rv5j1201	341	19	Ehrlichia	Ehrlichia	NNP
cord-022561-rv5j1201	341	20	canis	canis	NN
cord-022561-rv5j1201	341	21	,	,	,
cord-022561-rv5j1201	341	22	and	and	CC
cord-022561-rv5j1201	341	23	feline	feline	JJ
cord-022561-rv5j1201	341	24	leukemia	leukemia	NN
cord-022561-rv5j1201	341	25	virus	virus	NN
cord-022561-rv5j1201	341	26	[	[	-LRB-
cord-022561-rv5j1201	341	27	FeLV	FeLV	NNP
cord-022561-rv5j1201	341	28	]	]	-RRB-
cord-022561-rv5j1201	341	29	)	)	-RRB-
cord-022561-rv5j1201	341	30	,	,	,
cord-022561-rv5j1201	341	31	sepsis	sepsis	NN
cord-022561-rv5j1201	341	32	,	,	,
cord-022561-rv5j1201	341	33	drugs	drug	NNS
cord-022561-rv5j1201	341	34	or	or	CC
cord-022561-rv5j1201	341	35	toxins	toxin	NNS
cord-022561-rv5j1201	341	36	(	(	-LRB-
cord-022561-rv5j1201	341	37	carprofen	carprofen	NN
cord-022561-rv5j1201	341	38	,	,	,
cord-022561-rv5j1201	341	39	chemotherapeutic	chemotherapeutic	JJ
cord-022561-rv5j1201	341	40	agents	agent	NNS
cord-022561-rv5j1201	341	41	,	,	,
cord-022561-rv5j1201	341	42	estrogen	estrogen	NN
cord-022561-rv5j1201	341	43	,	,	,
cord-022561-rv5j1201	341	44	metronidazole	metronidazole	NNP
cord-022561-rv5j1201	341	45	,	,	,
cord-022561-rv5j1201	341	46	mitotane	mitotane	NNP
cord-022561-rv5j1201	341	47	,	,	,
cord-022561-rv5j1201	341	48	and	and	CC
cord-022561-rv5j1201	341	49	phenobarbital	phenobarbital	NN
cord-022561-rv5j1201	341	50	)	)	-RRB-
cord-022561-rv5j1201	341	51	,	,	,
cord-022561-rv5j1201	341	52	and	and	CC
cord-022561-rv5j1201	341	53	irradiation	irradiation	NN
cord-022561-rv5j1201	341	54	.	.	.
cord-022561-rv5j1201	342	1	Direct	direct	JJ
cord-022561-rv5j1201	342	2	hematopoietic	hematopoietic	JJ
cord-022561-rv5j1201	342	3	or	or	CC
cord-022561-rv5j1201	342	4	stromal	stromal	JJ
cord-022561-rv5j1201	342	5	cytotoxicity	cytotoxicity	NN
cord-022561-rv5j1201	342	6	and	and	CC
cord-022561-rv5j1201	342	7	altered	alter	VBN
cord-022561-rv5j1201	342	8	marrow	marrow	NN
cord-022561-rv5j1201	342	9	microvasculature	microvasculature	NN
cord-022561-rv5j1201	342	10	(	(	-LRB-
cord-022561-rv5j1201	342	11	disseminated	disseminate	VBN
cord-022561-rv5j1201	342	12	intravascular	intravascular	JJ
cord-022561-rv5j1201	342	13	coagulation	coagulation	NN
cord-022561-rv5j1201	342	14	)	)	-RRB-
cord-022561-rv5j1201	342	15	are	be	VBP
cord-022561-rv5j1201	342	16	proposed	propose	VBN
cord-022561-rv5j1201	342	17	pathogeneses	pathogenese	NNS
cord-022561-rv5j1201	342	18	.	.	.
cord-022561-rv5j1201	343	1	Extensive	extensive	JJ
cord-022561-rv5j1201	343	2	marrow	marrow	NN
cord-022561-rv5j1201	343	3	necrosis	necrosis	NN
cord-022561-rv5j1201	343	4	results	result	NNS
cord-022561-rv5j1201	343	5	in	in	IN
cord-022561-rv5j1201	343	6	decreased	decrease	VBN
cord-022561-rv5j1201	343	7	hematopoiesis	hematopoiesis	NN
cord-022561-rv5j1201	343	8	and	and	CC
cord-022561-rv5j1201	343	9	subsequent	subsequent	JJ
cord-022561-rv5j1201	343	10	blood	blood	NN
cord-022561-rv5j1201	343	11	cytopenias	cytopenia	NNS
cord-022561-rv5j1201	343	12	,	,	,
cord-022561-rv5j1201	343	13	including	include	VBG
cord-022561-rv5j1201	343	14	anemia	anemia	NN
cord-022561-rv5j1201	343	15	,	,	,
cord-022561-rv5j1201	343	16	neutropenia	neutropenia	NN
cord-022561-rv5j1201	343	17	,	,	,
cord-022561-rv5j1201	343	18	and	and	CC
cord-022561-rv5j1201	343	19	thrombocytopenia	thrombocytopenia	NN
cord-022561-rv5j1201	343	20	.	.	.
cord-022561-rv5j1201	344	1	If	if	IN
cord-022561-rv5j1201	344	2	the	the	DT
cord-022561-rv5j1201	344	3	animal	animal	NN
cord-022561-rv5j1201	344	4	survives	survive	VBZ
cord-022561-rv5j1201	344	5	the	the	DT
cord-022561-rv5j1201	344	6	initial	initial	JJ
cord-022561-rv5j1201	344	7	insult	insult	NN
cord-022561-rv5j1201	344	8	,	,	,
cord-022561-rv5j1201	344	9	the	the	DT
cord-022561-rv5j1201	344	10	marrow	marrow	NN
cord-022561-rv5j1201	344	11	may	may	MD
cord-022561-rv5j1201	344	12	recover	recover	VB
cord-022561-rv5j1201	344	13	and	and	CC
cord-022561-rv5j1201	344	14	resume	resume	VB
cord-022561-rv5j1201	344	15	normal	normal	JJ
cord-022561-rv5j1201	344	16	hematopoiesis	hematopoiesis	NN
cord-022561-rv5j1201	344	17	,	,	,
cord-022561-rv5j1201	344	18	or	or	CC
cord-022561-rv5j1201	344	19	it	-PRON-	PRP
cord-022561-rv5j1201	344	20	may	may	MD
cord-022561-rv5j1201	344	21	undergo	undergo	VB
cord-022561-rv5j1201	344	22	scar	scar	NN
cord-022561-rv5j1201	344	23	formation	formation	NN
cord-022561-rv5j1201	344	24	,	,	,
cord-022561-rv5j1201	344	25	termed	term	VBD
cord-022561-rv5j1201	344	26	myelofibrosis	myelofibrosis	NN
cord-022561-rv5j1201	344	27	.	.	.
cord-022561-rv5j1201	345	1	concentrations	concentration	NNS
cord-022561-rv5j1201	345	2	is	be	VBZ
cord-022561-rv5j1201	345	3	not	not	RB
cord-022561-rv5j1201	345	4	possible	possible	JJ
cord-022561-rv5j1201	345	5	due	due	IN
cord-022561-rv5j1201	345	6	to	to	IN
cord-022561-rv5j1201	345	7	perimortem	perimortem	NN
cord-022561-rv5j1201	345	8	coagulation	coagulation	NN
cord-022561-rv5j1201	345	9	.	.	.
cord-022561-rv5j1201	346	1	However	however	RB
cord-022561-rv5j1201	346	2	,	,	,
cord-022561-rv5j1201	346	3	a	a	DT
cord-022561-rv5j1201	346	4	complete	complete	JJ
cord-022561-rv5j1201	346	5	blood	blood	NN
cord-022561-rv5j1201	346	6	count	count	NN
cord-022561-rv5j1201	346	7	(	(	-LRB-
cord-022561-rv5j1201	346	8	CBC	CBC	NNP
cord-022561-rv5j1201	346	9	)	)	-RRB-
cord-022561-rv5j1201	346	10	with	with	IN
cord-022561-rv5j1201	346	11	microscopic	microscopic	JJ
cord-022561-rv5j1201	346	12	blood	blood	NN
cord-022561-rv5j1201	346	13	smear	smear	NN
cord-022561-rv5j1201	346	14	evaluation	evaluation	NN
cord-022561-rv5j1201	346	15	is	be	VBZ
cord-022561-rv5j1201	346	16	the	the	DT
cord-022561-rv5j1201	346	17	foundation	foundation	NN
cord-022561-rv5j1201	346	18	for	for	IN
cord-022561-rv5j1201	346	19	antemortem	antemortem	NNP
cord-022561-rv5j1201	346	20	assessment	assessment	NN
cord-022561-rv5j1201	346	21	of	of	IN
cord-022561-rv5j1201	346	22	blood	blood	NN
cord-022561-rv5j1201	346	23	cells	cell	NNS
cord-022561-rv5j1201	346	24	.	.	.
cord-022561-rv5j1201	347	1	Anemia	anemia	NN
cord-022561-rv5j1201	347	2	.	.	.
cord-022561-rv5j1201	348	1	Anemia	anemia	NN
cord-022561-rv5j1201	348	2	causes	cause	VBZ
cord-022561-rv5j1201	348	3	clinical	clinical	JJ
cord-022561-rv5j1201	348	4	signs	sign	NNS
cord-022561-rv5j1201	348	5	referable	referable	JJ
cord-022561-rv5j1201	348	6	to	to	IN
cord-022561-rv5j1201	348	7	decreased	decrease	VBN
cord-022561-rv5j1201	348	8	red	red	JJ
cord-022561-rv5j1201	348	9	hemoglobin	hemoglobin	NN
cord-022561-rv5j1201	348	10	pigment	pigment	NN
cord-022561-rv5j1201	348	11	(	(	-LRB-
cord-022561-rv5j1201	348	12	e.g.	e.g.	RB
cord-022561-rv5j1201	348	13	,	,	,
cord-022561-rv5j1201	348	14	pale	pale	JJ
cord-022561-rv5j1201	348	15	mucous	mucous	JJ
cord-022561-rv5j1201	348	16	membranes	membrane	NNS
cord-022561-rv5j1201	348	17	)	)	-RRB-
cord-022561-rv5j1201	348	18	,	,	,
cord-022561-rv5j1201	348	19	decreased	decrease	VBD
cord-022561-rv5j1201	348	20	oxygen	oxygen	NN
cord-022561-rv5j1201	348	21	-	-	HYPH
cord-022561-rv5j1201	348	22	carrying	carry	VBG
cord-022561-rv5j1201	348	23	capacity	capacity	NN
cord-022561-rv5j1201	348	24	(	(	-LRB-
cord-022561-rv5j1201	348	25	e.g.	e.g.	RB
cord-022561-rv5j1201	348	26	,	,	,
cord-022561-rv5j1201	348	27	depression	depression	NN
cord-022561-rv5j1201	348	28	,	,	,
cord-022561-rv5j1201	348	29	lethargy	lethargy	NN
cord-022561-rv5j1201	348	30	,	,	,
cord-022561-rv5j1201	348	31	weakness	weakness	NN
cord-022561-rv5j1201	348	32	,	,	,
cord-022561-rv5j1201	348	33	and	and	CC
cord-022561-rv5j1201	348	34	exercise	exercise	VB
cord-022561-rv5j1201	348	35	tolerance	tolerance	NN
cord-022561-rv5j1201	348	36	)	)	-RRB-
cord-022561-rv5j1201	348	37	,	,	,
cord-022561-rv5j1201	348	38	and	and	CC
cord-022561-rv5j1201	348	39	decreased	decrease	VBD
cord-022561-rv5j1201	348	40	blood	blood	NN
cord-022561-rv5j1201	348	41	viscosity	viscosity	NN
cord-022561-rv5j1201	348	42	(	(	-LRB-
cord-022561-rv5j1201	348	43	e.g.	e.g.	RB
cord-022561-rv5j1201	348	44	,	,	,
cord-022561-rv5j1201	348	45	heart	heart	NN
cord-022561-rv5j1201	348	46	murmur	murmur	NN
cord-022561-rv5j1201	348	47	)	)	-RRB-
cord-022561-rv5j1201	348	48	.	.	.
cord-022561-rv5j1201	349	1	Recumbency	Recumbency	NNP
cord-022561-rv5j1201	349	2	,	,	,
cord-022561-rv5j1201	349	3	seizures	seizure	NNS
cord-022561-rv5j1201	349	4	,	,	,
cord-022561-rv5j1201	349	5	syncope	syncope	NN
cord-022561-rv5j1201	349	6	,	,	,
cord-022561-rv5j1201	349	7	or	or	CC
cord-022561-rv5j1201	349	8	coma	coma	NN
cord-022561-rv5j1201	349	9	may	may	MD
cord-022561-rv5j1201	349	10	occur	occur	VB
cord-022561-rv5j1201	349	11	with	with	IN
cord-022561-rv5j1201	349	12	severe	severe	JJ
cord-022561-rv5j1201	349	13	anemia	anemia	NN
cord-022561-rv5j1201	349	14	.	.	.
cord-022561-rv5j1201	350	1	Anemia	anemia	NN
cord-022561-rv5j1201	350	2	is	be	VBZ
cord-022561-rv5j1201	350	3	confirmed	confirm	VBN
cord-022561-rv5j1201	350	4	by	by	IN
cord-022561-rv5j1201	350	5	identifying	identify	VBG
cord-022561-rv5j1201	350	6	a	a	DT
cord-022561-rv5j1201	350	7	decreased	decrease	VBN
cord-022561-rv5j1201	350	8	hemoglobin	hemoglobin	NN
cord-022561-rv5j1201	350	9	concentration	concentration	NN
cord-022561-rv5j1201	350	10	or	or	CC
cord-022561-rv5j1201	350	11	reduced	reduce	VBN
cord-022561-rv5j1201	350	12	erythrocyte	erythrocyte	NN
cord-022561-rv5j1201	350	13	mass	mass	NN
cord-022561-rv5j1201	350	14	,	,	,
cord-022561-rv5j1201	350	15	as	as	IN
cord-022561-rv5j1201	350	16	measured	measure	VBN
cord-022561-rv5j1201	350	17	by	by	IN
cord-022561-rv5j1201	350	18	the	the	DT
cord-022561-rv5j1201	350	19	packed	pack	VBN
cord-022561-rv5j1201	350	20	-	-	HYPH
cord-022561-rv5j1201	350	21	cell	cell	NN
cord-022561-rv5j1201	350	22	volume	volume	NN
cord-022561-rv5j1201	350	23	,	,	,
cord-022561-rv5j1201	350	24	hematocrit	hematocrit	NN
cord-022561-rv5j1201	350	25	,	,	,
cord-022561-rv5j1201	350	26	or	or	CC
cord-022561-rv5j1201	350	27	red	red	JJ
cord-022561-rv5j1201	350	28	blood	blood	NN
cord-022561-rv5j1201	350	29	cell	cell	NN
cord-022561-rv5j1201	350	30	concentration	concentration	NN
cord-022561-rv5j1201	350	31	.	.	.
cord-022561-rv5j1201	351	1	The	the	DT
cord-022561-rv5j1201	351	2	three	three	CD
cord-022561-rv5j1201	351	3	general	general	JJ
cord-022561-rv5j1201	351	4	causes	cause	NNS
cord-022561-rv5j1201	351	5	of	of	IN
cord-022561-rv5j1201	351	6	anemia	anemia	NN
cord-022561-rv5j1201	351	7	are	be	VBP
cord-022561-rv5j1201	351	8	blood	blood	NN
cord-022561-rv5j1201	351	9	loss	loss	NN
cord-022561-rv5j1201	351	10	(	(	-LRB-
cord-022561-rv5j1201	351	11	hemorrhage	hemorrhage	NN
cord-022561-rv5j1201	351	12	)	)	-RRB-
cord-022561-rv5j1201	351	13	,	,	,
cord-022561-rv5j1201	351	14	red	red	JJ
cord-022561-rv5j1201	351	15	blood	blood	NN
cord-022561-rv5j1201	351	16	cell	cell	NN
cord-022561-rv5j1201	351	17	destruction	destruction	NN
cord-022561-rv5j1201	351	18	or	or	CC
cord-022561-rv5j1201	351	19	lysis	lysis	NN
cord-022561-rv5j1201	351	20	(	(	-LRB-
cord-022561-rv5j1201	351	21	hemolysis	hemolysis	NN
cord-022561-rv5j1201	351	22	)	)	-RRB-
cord-022561-rv5j1201	351	23	,	,	,
cord-022561-rv5j1201	351	24	and	and	CC
cord-022561-rv5j1201	351	25	decreased	decrease	VBD
cord-022561-rv5j1201	351	26	red	red	JJ
cord-022561-rv5j1201	351	27	blood	blood	NN
cord-022561-rv5j1201	351	28	cell	cell	NN
cord-022561-rv5j1201	351	29	production	production	NN
cord-022561-rv5j1201	351	30	(	(	-LRB-
cord-022561-rv5j1201	351	31	erythroid	erythroid	NN
cord-022561-rv5j1201	351	32	hypoplasia	hypoplasia	NN
cord-022561-rv5j1201	351	33	)	)	-RRB-
cord-022561-rv5j1201	351	34	.	.	.
cord-022561-rv5j1201	352	1	Classifying	classify	VBG
cord-022561-rv5j1201	352	2	anemia	anemia	NN
cord-022561-rv5j1201	352	3	as	as	IN
cord-022561-rv5j1201	352	4	regenerative	regenerative	JJ
cord-022561-rv5j1201	352	5	or	or	CC
cord-022561-rv5j1201	352	6	nonregenerative	nonregenerative	NN
cord-022561-rv5j1201	352	7	is	be	VBZ
cord-022561-rv5j1201	352	8	clinically	clinically	RB
cord-022561-rv5j1201	352	9	useful	useful	JJ
cord-022561-rv5j1201	352	10	because	because	IN
cord-022561-rv5j1201	352	11	it	-PRON-	PRP
cord-022561-rv5j1201	352	12	provides	provide	VBZ
cord-022561-rv5j1201	352	13	information	information	NN
cord-022561-rv5j1201	352	14	about	about	IN
cord-022561-rv5j1201	352	15	the	the	DT
cord-022561-rv5j1201	352	16	mechanism	mechanism	NN
cord-022561-rv5j1201	352	17	of	of	IN
cord-022561-rv5j1201	352	18	disease	disease	NN
cord-022561-rv5j1201	352	19	;	;	,
cord-022561-rv5j1201	352	20	regenerative	regenerative	JJ
cord-022561-rv5j1201	352	21	anemia	anemia	NN
cord-022561-rv5j1201	352	22	indicates	indicate	VBZ
cord-022561-rv5j1201	352	23	hemorrhage	hemorrhage	NN
cord-022561-rv5j1201	352	24	or	or	CC
cord-022561-rv5j1201	352	25	hemolysis	hemolysis	NN
cord-022561-rv5j1201	352	26	,	,	,
cord-022561-rv5j1201	352	27	whereas	whereas	IN
cord-022561-rv5j1201	352	28	erythroid	erythroid	JJ
cord-022561-rv5j1201	352	29	hypoplasia	hypoplasia	NN
cord-022561-rv5j1201	352	30	or	or	CC
cord-022561-rv5j1201	352	31	aplasia	aplasia	NNP
cord-022561-rv5j1201	352	32	causes	cause	VBZ
cord-022561-rv5j1201	352	33	nonregenerative	nonregenerative	JJ
cord-022561-rv5j1201	352	34	anemia	anemia	NN
cord-022561-rv5j1201	352	35	(	(	-LRB-
cord-022561-rv5j1201	352	36	Table	Table	NNP
cord-022561-rv5j1201	352	37	13	13	CD
cord-022561-rv5j1201	352	38	-2	-2	CD
cord-022561-rv5j1201	352	39	)	)	-RRB-
cord-022561-rv5j1201	352	40	.	.	.
cord-022561-rv5j1201	353	1	The	the	DT
cord-022561-rv5j1201	353	2	hallmark	hallmark	NN
cord-022561-rv5j1201	353	3	of	of	IN
cord-022561-rv5j1201	353	4	regenerative	regenerative	JJ
cord-022561-rv5j1201	353	5	anemias	anemia	NNS
cord-022561-rv5j1201	353	6	,	,	,
cord-022561-rv5j1201	353	7	except	except	IN
cord-022561-rv5j1201	353	8	in	in	IN
cord-022561-rv5j1201	353	9	horses	horse	NNS
cord-022561-rv5j1201	353	10	,	,	,
cord-022561-rv5j1201	353	11	is	be	VBZ
cord-022561-rv5j1201	353	12	reticulocytosis	reticulocytosis	NNP
cord-022561-rv5j1201	353	13	(	(	-LRB-
cord-022561-rv5j1201	353	14	i.e.	i.e.	FW
cord-022561-rv5j1201	353	15	,	,	,
cord-022561-rv5j1201	353	16	increased	increase	VBN
cord-022561-rv5j1201	353	17	numbers	number	NNS
cord-022561-rv5j1201	353	18	of	of	IN
cord-022561-rv5j1201	353	19	circulating	circulate	VBG
cord-022561-rv5j1201	353	20	reticulocytes	reticulocyte	NNS
cord-022561-rv5j1201	353	21	[	[	-LRB-
cord-022561-rv5j1201	353	22	immature	immature	JJ
cord-022561-rv5j1201	353	23	erythrocytes	erythrocyte	NNS
cord-022561-rv5j1201	353	24	]	]	-RRB-
cord-022561-rv5j1201	353	25	)	)	-RRB-
cord-022561-rv5j1201	353	26	,	,	,
cord-022561-rv5j1201	353	27	which	which	WDT
cord-022561-rv5j1201	353	28	is	be	VBZ
cord-022561-rv5j1201	353	29	evident	evident	JJ
cord-022561-rv5j1201	353	30	as	as	IN
cord-022561-rv5j1201	353	31	polychromasia	polychromasia	NNP
cord-022561-rv5j1201	353	32	on	on	IN
cord-022561-rv5j1201	353	33	a	a	DT
cord-022561-rv5j1201	353	34	routinely	routinely	RB
cord-022561-rv5j1201	353	35	stained	stain	VBN
cord-022561-rv5j1201	353	36	blood	blood	NN
cord-022561-rv5j1201	353	37	smear	smear	NN
cord-022561-rv5j1201	353	38	(	(	-LRB-
cord-022561-rv5j1201	353	39	see	see	VB
cord-022561-rv5j1201	353	40	Fig	Fig	NNP
cord-022561-rv5j1201	353	41	.	.	.
cord-022561-rv5j1201	353	42	13	13	CD
cord-022561-rv5j1201	353	43	-5	-5	CD
cord-022561-rv5j1201	353	44	)	)	-RRB-
cord-022561-rv5j1201	353	45	.	.	.
cord-022561-rv5j1201	354	1	Reticulocytosis	Reticulocytosis	NNP
cord-022561-rv5j1201	354	2	indicates	indicate	VBZ
cord-022561-rv5j1201	354	3	increased	increase	VBN
cord-022561-rv5j1201	354	4	bone	bone	NN
cord-022561-rv5j1201	354	5	marrow	marrow	NN
cord-022561-rv5j1201	354	6	erythropoiesis	erythropoiesis	NN
cord-022561-rv5j1201	354	7	(	(	-LRB-
cord-022561-rv5j1201	354	8	Fig	Fig	NNP
cord-022561-rv5j1201	354	9	.	.	.
cord-022561-rv5j1201	354	10	13	13	CD
cord-022561-rv5j1201	354	11	-	-	SYM
cord-022561-rv5j1201	354	12	7	7	CD
cord-022561-rv5j1201	354	13	)	)	-RRB-
cord-022561-rv5j1201	354	14	and	and	CC
cord-022561-rv5j1201	354	15	release	release	NN
cord-022561-rv5j1201	354	16	of	of	IN
cord-022561-rv5j1201	354	17	erythrocytes	erythrocyte	NNS
cord-022561-rv5j1201	354	18	before	before	IN
cord-022561-rv5j1201	354	19	they	-PRON-	PRP
cord-022561-rv5j1201	354	20	are	be	VBP
cord-022561-rv5j1201	354	21	fully	fully	RB
cord-022561-rv5j1201	354	22	mature	mature	JJ
cord-022561-rv5j1201	354	23	.	.	.
cord-022561-rv5j1201	355	1	Reticulocytosis	Reticulocytosis	NNP
cord-022561-rv5j1201	355	2	is	be	VBZ
cord-022561-rv5j1201	355	3	an	an	DT
cord-022561-rv5j1201	355	4	appropriate	appropriate	JJ
cord-022561-rv5j1201	355	5	marrow	marrow	NN
cord-022561-rv5j1201	355	6	response	response	NN
cord-022561-rv5j1201	355	7	to	to	IN
cord-022561-rv5j1201	355	8	anemia	anemia	NN
cord-022561-rv5j1201	355	9	and	and	CC
cord-022561-rv5j1201	355	10	is	be	VBZ
cord-022561-rv5j1201	355	11	often	often	RB
cord-022561-rv5j1201	355	12	seen	see	VBN
cord-022561-rv5j1201	355	13	with	with	IN
cord-022561-rv5j1201	355	14	hemorrhage	hemorrhage	NN
cord-022561-rv5j1201	355	15	or	or	CC
cord-022561-rv5j1201	355	16	hemolysis	hemolysis	NN
cord-022561-rv5j1201	355	17	.	.	.
cord-022561-rv5j1201	356	1	On	on	IN
cord-022561-rv5j1201	356	2	a	a	DT
cord-022561-rv5j1201	356	3	CBC	CBC	NNP
cord-022561-rv5j1201	356	4	a	a	DT
cord-022561-rv5j1201	356	5	strong	strong	JJ
cord-022561-rv5j1201	356	6	regenerative	regenerative	JJ
cord-022561-rv5j1201	356	7	response	response	NN
cord-022561-rv5j1201	356	8	may	may	MD
cord-022561-rv5j1201	356	9	produce	produce	VB
cord-022561-rv5j1201	356	10	an	an	DT
cord-022561-rv5j1201	356	11	increased	increase	VBN
cord-022561-rv5j1201	356	12	mean	mean	JJ
cord-022561-rv5j1201	356	13	cell	cell	NN
cord-022561-rv5j1201	356	14	volume	volume	NN
cord-022561-rv5j1201	356	15	(	(	-LRB-
cord-022561-rv5j1201	356	16	MCV	MCV	NNP
cord-022561-rv5j1201	356	17	)	)	-RRB-
cord-022561-rv5j1201	356	18	and	and	CC
cord-022561-rv5j1201	356	19	decreased	decrease	VBD
cord-022561-rv5j1201	356	20	mean	mean	JJ
cord-022561-rv5j1201	356	21	cell	cell	NN
cord-022561-rv5j1201	356	22	hemoglobin	hemoglobin	NN
cord-022561-rv5j1201	356	23	concentration	concentration	NN
cord-022561-rv5j1201	356	24	(	(	-LRB-
cord-022561-rv5j1201	356	25	MCHC	MCHC	NNP
cord-022561-rv5j1201	356	26	)	)	-RRB-
cord-022561-rv5j1201	356	27	because	because	IN
cord-022561-rv5j1201	356	28	reticulocytes	reticulocyte	NNS
cord-022561-rv5j1201	356	29	are	be	VBP
cord-022561-rv5j1201	356	30	larger	large	JJR
cord-022561-rv5j1201	356	31	and	and	CC
cord-022561-rv5j1201	356	32	have	have	VBP
cord-022561-rv5j1201	356	33	a	a	DT
cord-022561-rv5j1201	356	34	lower	low	JJR
cord-022561-rv5j1201	356	35	hemoglobin	hemoglobin	NN
cord-022561-rv5j1201	356	36	concentration	concentration	NN
cord-022561-rv5j1201	356	37	than	than	IN
cord-022561-rv5j1201	356	38	mature	mature	JJ
cord-022561-rv5j1201	356	39	erythrocytes	erythrocyte	NNS
cord-022561-rv5j1201	356	40	.	.	.
cord-022561-rv5j1201	357	1	Horses	horse	NNS
cord-022561-rv5j1201	357	2	are	be	VBP
cord-022561-rv5j1201	357	3	an	an	DT
cord-022561-rv5j1201	357	4	exception	exception	NN
cord-022561-rv5j1201	357	5	to	to	IN
cord-022561-rv5j1201	357	6	this	this	DT
cord-022561-rv5j1201	357	7	classification	classification	NN
cord-022561-rv5j1201	357	8	scheme	scheme	NN
cord-022561-rv5j1201	357	9	because	because	IN
cord-022561-rv5j1201	357	10	they	-PRON-	PRP
cord-022561-rv5j1201	357	11	do	do	VBP
cord-022561-rv5j1201	357	12	not	not	RB
cord-022561-rv5j1201	357	13	release	release	VB
cord-022561-rv5j1201	357	14	reticulocytes	reticulocyte	NNS
cord-022561-rv5j1201	357	15	into	into	IN
cord-022561-rv5j1201	357	16	circulation	circulation	NN
cord-022561-rv5j1201	357	17	,	,	,
cord-022561-rv5j1201	357	18	even	even	RB
cord-022561-rv5j1201	357	19	with	with	IN
cord-022561-rv5j1201	357	20	erythroid	erythroid	JJ
cord-022561-rv5j1201	357	21	hyperplasia	hyperplasia	NN
cord-022561-rv5j1201	357	22	.	.	.
cord-022561-rv5j1201	358	1	Horses	horse	NNS
cord-022561-rv5j1201	358	2	with	with	IN
cord-022561-rv5j1201	358	3	a	a	DT
cord-022561-rv5j1201	358	4	regenerative	regenerative	JJ
cord-022561-rv5j1201	358	5	response	response	NN
cord-022561-rv5j1201	358	6	may	may	MD
cord-022561-rv5j1201	358	7	have	have	VB
cord-022561-rv5j1201	358	8	an	an	DT
cord-022561-rv5j1201	358	9	increased	increase	VBN
cord-022561-rv5j1201	358	10	MCV	MCV	NNP
cord-022561-rv5j1201	358	11	and	and	CC
cord-022561-rv5j1201	358	12	red	red	JJ
cord-022561-rv5j1201	358	13	cell	cell	NN
cord-022561-rv5j1201	358	14	distribution	distribution	NN
cord-022561-rv5j1201	358	15	width	width	NN
cord-022561-rv5j1201	358	16	(	(	-LRB-
cord-022561-rv5j1201	358	17	an	an	DT
cord-022561-rv5j1201	358	18	index	index	NN
cord-022561-rv5j1201	358	19	of	of	IN
cord-022561-rv5j1201	358	20	variation	variation	NN
cord-022561-rv5j1201	358	21	in	in	IN
cord-022561-rv5j1201	358	22	cell	cell	NN
cord-022561-rv5j1201	358	23	size	size	NN
cord-022561-rv5j1201	358	24	)	)	-RRB-
cord-022561-rv5j1201	358	25	.	.	.
cord-022561-rv5j1201	359	1	But	but	CC
cord-022561-rv5j1201	359	2	definitive	definitive	JJ
cord-022561-rv5j1201	359	3	determination	determination	NN
cord-022561-rv5j1201	359	4	of	of	IN
cord-022561-rv5j1201	359	5	regeneration	regeneration	NN
cord-022561-rv5j1201	359	6	in	in	IN
cord-022561-rv5j1201	359	7	a	a	DT
cord-022561-rv5j1201	359	8	horse	horse	NN
cord-022561-rv5j1201	359	9	requires	require	VBZ
cord-022561-rv5j1201	359	10	demonstration	demonstration	NN
cord-022561-rv5j1201	359	11	of	of	IN
cord-022561-rv5j1201	359	12	erythroid	erythroid	JJ
cord-022561-rv5j1201	359	13	hyperplasia	hyperplasia	NN
cord-022561-rv5j1201	359	14	via	via	IN
cord-022561-rv5j1201	359	15	bone	bone	NN
cord-022561-rv5j1201	359	16	marrow	marrow	NN
cord-022561-rv5j1201	359	17	examination	examination	NN
cord-022561-rv5j1201	359	18	or	or	CC
cord-022561-rv5j1201	359	19	an	an	DT
cord-022561-rv5j1201	359	20	increasing	increase	VBG
cord-022561-rv5j1201	359	21	red	red	JJ
cord-022561-rv5j1201	359	22	cell	cell	NN
cord-022561-rv5j1201	359	23	mass	mass	NN
cord-022561-rv5j1201	359	24	over	over	IN
cord-022561-rv5j1201	359	25	sequential	sequential	JJ
cord-022561-rv5j1201	359	26	CBCs	cbc	NNS
cord-022561-rv5j1201	359	27	.	.	.
cord-022561-rv5j1201	360	1	In	in	IN
cord-022561-rv5j1201	360	2	addition	addition	NN
cord-022561-rv5j1201	360	3	to	to	IN
cord-022561-rv5j1201	360	4	reticulocytosis	reticulocytosis	NNP
cord-022561-rv5j1201	360	5	there	there	EX
cord-022561-rv5j1201	360	6	may	may	MD
cord-022561-rv5j1201	360	7	be	be	VB
cord-022561-rv5j1201	360	8	increased	increase	VBN
cord-022561-rv5j1201	360	9	numbers	number	NNS
cord-022561-rv5j1201	360	10	of	of	IN
cord-022561-rv5j1201	360	11	nucleated	nucleated	JJ
cord-022561-rv5j1201	360	12	red	red	JJ
cord-022561-rv5j1201	360	13	blood	blood	NN
cord-022561-rv5j1201	360	14	cells	cell	NNS
cord-022561-rv5j1201	360	15	(	(	-LRB-
cord-022561-rv5j1201	360	16	nRBCs	nrbcs	RB
cord-022561-rv5j1201	360	17	)	)	-RRB-
cord-022561-rv5j1201	360	18	in	in	IN
cord-022561-rv5j1201	360	19	circulation	circulation	NN
cord-022561-rv5j1201	360	20	with	with	IN
cord-022561-rv5j1201	360	21	erythrocyte	erythrocyte	NN
cord-022561-rv5j1201	360	22	regeneration	regeneration	NN
cord-022561-rv5j1201	360	23	,	,	,
cord-022561-rv5j1201	360	24	termed	term	VBD
cord-022561-rv5j1201	360	25	appropriate	appropriate	JJ
cord-022561-rv5j1201	360	26	metarubricytosis	metarubricytosis	NN
cord-022561-rv5j1201	360	27	.	.	.
cord-022561-rv5j1201	361	1	When	when	WRB
cord-022561-rv5j1201	361	2	nRBCs	nrbcs	EX
cord-022561-rv5j1201	361	3	are	be	VBP
cord-022561-rv5j1201	361	4	present	present	JJ
cord-022561-rv5j1201	361	5	as	as	IN
cord-022561-rv5j1201	361	6	part	part	NN
cord-022561-rv5j1201	361	7	of	of	IN
cord-022561-rv5j1201	361	8	a	a	DT
cord-022561-rv5j1201	361	9	regenerative	regenerative	JJ
cord-022561-rv5j1201	361	10	response	response	NN
cord-022561-rv5j1201	361	11	,	,	,
cord-022561-rv5j1201	361	12	they	-PRON-	PRP
cord-022561-rv5j1201	361	13	should	should	MD
cord-022561-rv5j1201	361	14	be	be	VB
cord-022561-rv5j1201	361	15	in	in	IN
cord-022561-rv5j1201	361	16	low	low	JJ
cord-022561-rv5j1201	361	17	numbers	number	NNS
cord-022561-rv5j1201	361	18	relative	relative	JJ
cord-022561-rv5j1201	361	19	to	to	IN
cord-022561-rv5j1201	361	20	the	the	DT
cord-022561-rv5j1201	361	21	numbers	number	NNS
cord-022561-rv5j1201	361	22	of	of	IN
cord-022561-rv5j1201	361	23	reticulocytes	reticulocyte	NNS
cord-022561-rv5j1201	361	24	.	.	.
cord-022561-rv5j1201	362	1	However	however	RB
cord-022561-rv5j1201	362	2	,	,	,
cord-022561-rv5j1201	362	3	the	the	DT
cord-022561-rv5j1201	362	4	presence	presence	NN
cord-022561-rv5j1201	362	5	of	of	IN
cord-022561-rv5j1201	362	6	circulating	circulate	VBG
cord-022561-rv5j1201	362	7	nRBCs	nrbcs	WP
cord-022561-rv5j1201	362	8	is	be	VBZ
cord-022561-rv5j1201	362	9	not	not	RB
cord-022561-rv5j1201	362	10	in	in	IN
cord-022561-rv5j1201	362	11	itself	-PRON-	PRP
cord-022561-rv5j1201	362	12	definitive	definitive	JJ
cord-022561-rv5j1201	362	13	evidence	evidence	NN
cord-022561-rv5j1201	362	14	of	of	IN
cord-022561-rv5j1201	362	15	regeneration	regeneration	NN
cord-022561-rv5j1201	362	16	and	and	CC
cord-022561-rv5j1201	362	17	may	may	MD
cord-022561-rv5j1201	362	18	signify	signify	VB
cord-022561-rv5j1201	362	19	dyserythropoiesis	dyserythropoiesis	NNP
cord-022561-rv5j1201	362	20	(	(	-LRB-
cord-022561-rv5j1201	362	21	e.g.	e.g.	RB
cord-022561-rv5j1201	362	22	,	,	,
cord-022561-rv5j1201	362	23	lead	lead	JJ
cord-022561-rv5j1201	362	24	poisoning	poisoning	NN
cord-022561-rv5j1201	362	25	or	or	CC
cord-022561-rv5j1201	362	26	bone	bone	NN
cord-022561-rv5j1201	362	27	marrow	marrow	NN
cord-022561-rv5j1201	362	28	disease	disease	NN
cord-022561-rv5j1201	362	29	)	)	-RRB-
cord-022561-rv5j1201	362	30	or	or	CC
cord-022561-rv5j1201	362	31	splenic	splenic	JJ
cord-022561-rv5j1201	362	32	dysfunction	dysfunction	NN
cord-022561-rv5j1201	362	33	.	.	.
cord-022561-rv5j1201	363	1	These	these	DT
cord-022561-rv5j1201	363	2	processes	process	NNS
cord-022561-rv5j1201	363	3	should	should	MD
cord-022561-rv5j1201	363	4	be	be	VB
cord-022561-rv5j1201	363	5	suspected	suspect	VBN
cord-022561-rv5j1201	363	6	when	when	WRB
cord-022561-rv5j1201	363	7	nRBCs	nRBCs	NNPS
cord-022561-rv5j1201	363	8	are	be	VBP
cord-022561-rv5j1201	363	9	increased	increase	VBN
cord-022561-rv5j1201	363	10	without	without	IN
cord-022561-rv5j1201	363	11	reticulocy-	reticulocy-	NN
cord-022561-rv5j1201	363	12	such	such	JJ
cord-022561-rv5j1201	363	13	as	as	IN
cord-022561-rv5j1201	363	14	into	into	IN
cord-022561-rv5j1201	363	15	the	the	DT
cord-022561-rv5j1201	363	16	peritoneal	peritoneal	JJ
cord-022561-rv5j1201	363	17	cavity	cavity	NN
cord-022561-rv5j1201	363	18	,	,	,
cord-022561-rv5j1201	363	19	because	because	IN
cord-022561-rv5j1201	363	20	iron	iron	NN
cord-022561-rv5j1201	363	21	is	be	VBZ
cord-022561-rv5j1201	363	22	not	not	RB
cord-022561-rv5j1201	363	23	lost	lose	VBN
cord-022561-rv5j1201	363	24	from	from	IN
cord-022561-rv5j1201	363	25	the	the	DT
cord-022561-rv5j1201	363	26	body	body	NN
cord-022561-rv5j1201	363	27	and	and	CC
cord-022561-rv5j1201	363	28	can	can	MD
cord-022561-rv5j1201	363	29	be	be	VB
cord-022561-rv5j1201	363	30	reused	reuse	VBN
cord-022561-rv5j1201	363	31	for	for	IN
cord-022561-rv5j1201	363	32	erythropoiesis	erythropoiesis	NN
cord-022561-rv5j1201	363	33	.	.	.
cord-022561-rv5j1201	364	1	In	in	IN
cord-022561-rv5j1201	364	2	hemolytic	hemolytic	JJ
cord-022561-rv5j1201	364	3	anemia	anemia	NN
cord-022561-rv5j1201	364	4	,	,	,
cord-022561-rv5j1201	364	5	erythrocytes	erythrocyte	NNS
cord-022561-rv5j1201	364	6	are	be	VBP
cord-022561-rv5j1201	364	7	destroyed	destroy	VBN
cord-022561-rv5j1201	364	8	at	at	IN
cord-022561-rv5j1201	364	9	an	an	DT
cord-022561-rv5j1201	364	10	increased	increase	VBN
cord-022561-rv5j1201	364	11	rate	rate	NN
cord-022561-rv5j1201	364	12	.	.	.
cord-022561-rv5j1201	365	1	Whether	whether	IN
cord-022561-rv5j1201	365	2	the	the	DT
cord-022561-rv5j1201	365	3	mechanism	mechanism	NN
cord-022561-rv5j1201	365	4	is	be	VBZ
cord-022561-rv5j1201	365	5	intravascular	intravascular	JJ
cord-022561-rv5j1201	365	6	or	or	CC
cord-022561-rv5j1201	365	7	extravascular	extravascular	JJ
cord-022561-rv5j1201	365	8	,	,	,
cord-022561-rv5j1201	365	9	or	or	CC
cord-022561-rv5j1201	365	10	a	a	DT
cord-022561-rv5j1201	365	11	combination	combination	NN
cord-022561-rv5j1201	365	12	,	,	,
cord-022561-rv5j1201	365	13	depends	depend	VBZ
cord-022561-rv5j1201	365	14	on	on	IN
cord-022561-rv5j1201	365	15	the	the	DT
cord-022561-rv5j1201	365	16	specific	specific	JJ
cord-022561-rv5j1201	365	17	disease	disease	NN
cord-022561-rv5j1201	365	18	process	process	NN
cord-022561-rv5j1201	365	19	(	(	-LRB-
cord-022561-rv5j1201	365	20	specific	specific	JJ
cord-022561-rv5j1201	365	21	diseases	disease	NNS
cord-022561-rv5j1201	365	22	are	be	VBP
cord-022561-rv5j1201	365	23	discussed	discuss	VBN
cord-022561-rv5j1201	365	24	later	later	RB
cord-022561-rv5j1201	365	25	in	in	IN
cord-022561-rv5j1201	365	26	this	this	DT
cord-022561-rv5j1201	365	27	chapter	chapter	NN
cord-022561-rv5j1201	365	28	)	)	-RRB-
cord-022561-rv5j1201	365	29	.	.	.
cord-022561-rv5j1201	366	1	Some	some	DT
cord-022561-rv5j1201	366	2	clinical	clinical	JJ
cord-022561-rv5j1201	366	3	indicators	indicator	NNS
cord-022561-rv5j1201	366	4	of	of	IN
cord-022561-rv5j1201	366	5	hemolytic	hemolytic	JJ
cord-022561-rv5j1201	366	6	anemia	anemia	NN
cord-022561-rv5j1201	366	7	and	and	CC
cord-022561-rv5j1201	366	8	their	-PRON-	PRP$
cord-022561-rv5j1201	366	9	pathogeneses	pathogenese	NNS
cord-022561-rv5j1201	366	10	are	be	VBP
cord-022561-rv5j1201	366	11	summarized	summarize	VBN
cord-022561-rv5j1201	366	12	in	in	IN
cord-022561-rv5j1201	366	13	Fig	Fig	NNP
cord-022561-rv5j1201	366	14	.	.	.
cord-022561-rv5j1201	366	15	 	 	_SP
cord-022561-rv5j1201	367	1	13	13	CD
cord-022561-rv5j1201	367	2	-9	-9	NN
cord-022561-rv5j1201	368	1	and	and	CC
cord-022561-rv5j1201	368	2	are	be	VBP
cord-022561-rv5j1201	368	3	further	further	RB
cord-022561-rv5j1201	368	4	described	describe	VBN
cord-022561-rv5j1201	368	5	in	in	IN
cord-022561-rv5j1201	368	6	the	the	DT
cord-022561-rv5j1201	368	7	following	follow	VBG
cord-022561-rv5j1201	368	8	discussion	discussion	NN
cord-022561-rv5j1201	368	9	.	.	.
cord-022561-rv5j1201	369	1	A	a	DT
cord-022561-rv5j1201	369	2	classic	classic	JJ
cord-022561-rv5j1201	369	3	sequela	sequela	NN
cord-022561-rv5j1201	369	4	of	of	IN
cord-022561-rv5j1201	369	5	hemolytic	hemolytic	JJ
cord-022561-rv5j1201	369	6	anemias	anemia	NNS
cord-022561-rv5j1201	369	7	in	in	IN
cord-022561-rv5j1201	369	8	general	general	JJ
cord-022561-rv5j1201	369	9	is	be	VBZ
cord-022561-rv5j1201	369	10	hyperbilirubinemia	hyperbilirubinemia	NNP
cord-022561-rv5j1201	369	11	,	,	,
cord-022561-rv5j1201	369	12	which	which	WDT
cord-022561-rv5j1201	369	13	is	be	VBZ
cord-022561-rv5j1201	369	14	an	an	DT
cord-022561-rv5j1201	369	15	increase	increase	NN
cord-022561-rv5j1201	369	16	in	in	IN
cord-022561-rv5j1201	369	17	the	the	DT
cord-022561-rv5j1201	369	18	plasma	plasma	NN
cord-022561-rv5j1201	369	19	bilirubin	bilirubin	NN
cord-022561-rv5j1201	369	20	concentration	concentration	NN
cord-022561-rv5j1201	369	21	.	.	.
cord-022561-rv5j1201	370	1	Bilirubin	bilirubin	NN
cord-022561-rv5j1201	370	2	is	be	VBZ
cord-022561-rv5j1201	370	3	a	a	DT
cord-022561-rv5j1201	370	4	yellow	yellow	JJ
cord-022561-rv5j1201	370	5	pigment	pigment	NN
cord-022561-rv5j1201	370	6	,	,	,
cord-022561-rv5j1201	370	7	which	which	WDT
cord-022561-rv5j1201	370	8	explains	explain	VBZ
cord-022561-rv5j1201	370	9	why	why	WRB
cord-022561-rv5j1201	370	10	hyperbilirubinemia	hyperbilirubinemia	NNP
cord-022561-rv5j1201	370	11	,	,	,
cord-022561-rv5j1201	370	12	if	if	IN
cord-022561-rv5j1201	370	13	severe	severe	JJ
cord-022561-rv5j1201	370	14	enough	enough	RB
cord-022561-rv5j1201	370	15	,	,	,
cord-022561-rv5j1201	370	16	causes	cause	VBZ
cord-022561-rv5j1201	370	17	icterus	icterus	NN
cord-022561-rv5j1201	370	18	-	-	:
cord-022561-rv5j1201	370	19	the	the	DT
cord-022561-rv5j1201	370	20	grossly	grossly	RB
cord-022561-rv5j1201	370	21	visible	visible	JJ
cord-022561-rv5j1201	370	22	yellowing	yellowing	NN
cord-022561-rv5j1201	370	23	of	of	IN
cord-022561-rv5j1201	370	24	fluid	fluid	NN
cord-022561-rv5j1201	370	25	or	or	CC
cord-022561-rv5j1201	370	26	tissues	tissue	NNS
cord-022561-rv5j1201	370	27	(	(	-LRB-
cord-022561-rv5j1201	370	28	Fig	Fig	NNP
cord-022561-rv5j1201	370	29	.	.	.
cord-022561-rv5j1201	370	30	13	13	CD
cord-022561-rv5j1201	370	31	-	-	SYM
cord-022561-rv5j1201	370	32	10	10	CD
cord-022561-rv5j1201	370	33	)	)	-RRB-
cord-022561-rv5j1201	370	34	.	.	.
cord-022561-rv5j1201	371	1	Icterus	Icterus	NNP
cord-022561-rv5j1201	371	2	,	,	,
cord-022561-rv5j1201	371	3	also	also	RB
cord-022561-rv5j1201	371	4	known	know	VBN
cord-022561-rv5j1201	371	5	as	as	IN
cord-022561-rv5j1201	371	6	jaundice	jaundice	NN
cord-022561-rv5j1201	371	7	,	,	,
cord-022561-rv5j1201	371	8	is	be	VBZ
cord-022561-rv5j1201	371	9	usually	usually	RB
cord-022561-rv5j1201	371	10	detectable	detectable	JJ
cord-022561-rv5j1201	371	11	when	when	WRB
cord-022561-rv5j1201	371	12	the	the	DT
cord-022561-rv5j1201	371	13	plasma	plasma	NN
cord-022561-rv5j1201	371	14	bilirubin	bilirubin	NN
cord-022561-rv5j1201	371	15	concentration	concentration	NN
cord-022561-rv5j1201	371	16	exceeds	exceed	VBZ
cord-022561-rv5j1201	371	17	2	2	CD
cord-022561-rv5j1201	371	18	mg	mg	NNP
cord-022561-rv5j1201	371	19	/	/	SYM
cord-022561-rv5j1201	371	20	dL.	dL.	NNS
cord-022561-rv5j1201	372	1	However	however	RB
cord-022561-rv5j1201	372	2	,	,	,
cord-022561-rv5j1201	372	3	it	-PRON-	PRP
cord-022561-rv5j1201	372	4	is	be	VBZ
cord-022561-rv5j1201	372	5	important	important	JJ
cord-022561-rv5j1201	372	6	to	to	TO
cord-022561-rv5j1201	372	7	note	note	VB
cord-022561-rv5j1201	372	8	that	that	IN
cord-022561-rv5j1201	372	9	hyperbilirubinemia	hyperbilirubinemia	NN
cord-022561-rv5j1201	372	10	and	and	CC
cord-022561-rv5j1201	372	11	icterus	icterus	NN
cord-022561-rv5j1201	372	12	are	be	VBP
cord-022561-rv5j1201	372	13	not	not	RB
cord-022561-rv5j1201	372	14	pathognomonic	pathognomonic	JJ
cord-022561-rv5j1201	372	15	for	for	IN
cord-022561-rv5j1201	372	16	hemolysis	hemolysis	NN
cord-022561-rv5j1201	372	17	and	and	CC
cord-022561-rv5j1201	372	18	may	may	MD
cord-022561-rv5j1201	372	19	also	also	RB
cord-022561-rv5j1201	372	20	occur	occur	VB
cord-022561-rv5j1201	372	21	with	with	IN
cord-022561-rv5j1201	372	22	conditions	condition	NNS
cord-022561-rv5j1201	372	23	of	of	IN
cord-022561-rv5j1201	372	24	impaired	impaired	JJ
cord-022561-rv5j1201	372	25	bile	bile	NN
cord-022561-rv5j1201	372	26	flow	flow	NN
cord-022561-rv5j1201	372	27	(	(	-LRB-
cord-022561-rv5j1201	372	28	cholestasis	cholestasis	NN
cord-022561-rv5j1201	372	29	)	)	-RRB-
cord-022561-rv5j1201	372	30	,	,	,
cord-022561-rv5j1201	372	31	such	such	JJ
cord-022561-rv5j1201	372	32	as	as	IN
cord-022561-rv5j1201	372	33	hepatopathy	hepatopathy	NNP
cord-022561-rv5j1201	372	34	or	or	CC
cord-022561-rv5j1201	372	35	cholangiopathy	cholangiopathy	NNP
cord-022561-rv5j1201	372	36	.	.	.
cord-022561-rv5j1201	373	1	In	in	IN
cord-022561-rv5j1201	373	2	addition	addition	NN
cord-022561-rv5j1201	373	3	to	to	IN
cord-022561-rv5j1201	373	4	icterus	icterus	NN
cord-022561-rv5j1201	373	5	,	,	,
cord-022561-rv5j1201	373	6	hemolytic	hemolytic	JJ
cord-022561-rv5j1201	373	7	anemia	anemia	NN
cord-022561-rv5j1201	373	8	often	often	RB
cord-022561-rv5j1201	373	9	results	result	VBZ
cord-022561-rv5j1201	373	10	in	in	IN
cord-022561-rv5j1201	373	11	splenomegaly	splenomegaly	NN
cord-022561-rv5j1201	373	12	,	,	,
cord-022561-rv5j1201	373	13	which	which	WDT
cord-022561-rv5j1201	373	14	is	be	VBZ
cord-022561-rv5j1201	373	15	secondary	secondary	JJ
cord-022561-rv5j1201	373	16	to	to	IN
cord-022561-rv5j1201	373	17	extravascular	extravascular	JJ
cord-022561-rv5j1201	373	18	hemolysis	hemolysis	NN
cord-022561-rv5j1201	373	19	and	and	CC
cord-022561-rv5j1201	373	20	macrophagic	macrophagic	JJ
cord-022561-rv5j1201	373	21	hyperplasia	hyperplasia	NN
cord-022561-rv5j1201	373	22	within	within	IN
cord-022561-rv5j1201	373	23	the	the	DT
cord-022561-rv5j1201	373	24	spleen	spleen	NN
cord-022561-rv5j1201	373	25	,	,	,
cord-022561-rv5j1201	373	26	as	as	RB
cord-022561-rv5j1201	373	27	well	well	RB
cord-022561-rv5j1201	373	28	as	as	IN
cord-022561-rv5j1201	373	29	splenic	splenic	JJ
cord-022561-rv5j1201	373	30	EMH	EMH	NNP
cord-022561-rv5j1201	373	31	.	.	.
cord-022561-rv5j1201	374	1	Splenomegaly	Splenomegaly	NNP
cord-022561-rv5j1201	374	2	may	may	MD
cord-022561-rv5j1201	374	3	also	also	RB
cord-022561-rv5j1201	374	4	occur	occur	VB
cord-022561-rv5j1201	374	5	in	in	IN
cord-022561-rv5j1201	374	6	other	other	JJ
cord-022561-rv5j1201	374	7	conditions	condition	NNS
cord-022561-rv5j1201	374	8	,	,	,
cord-022561-rv5j1201	374	9	as	as	IN
cord-022561-rv5j1201	374	10	discussed	discuss	VBN
cord-022561-rv5j1201	374	11	elsewhere	elsewhere	RB
cord-022561-rv5j1201	374	12	in	in	IN
cord-022561-rv5j1201	374	13	this	this	DT
cord-022561-rv5j1201	374	14	chapter	chapter	NN
cord-022561-rv5j1201	374	15	.	.	.
cord-022561-rv5j1201	375	1	Intravascular	intravascular	JJ
cord-022561-rv5j1201	375	2	hemolysis	hemolysis	NN
cord-022561-rv5j1201	375	3	is	be	VBZ
cord-022561-rv5j1201	375	4	grossly	grossly	RB
cord-022561-rv5j1201	375	5	evident	evident	JJ
cord-022561-rv5j1201	375	6	as	as	IN
cord-022561-rv5j1201	375	7	pink	pink	JJ
cord-022561-rv5j1201	375	8	-	-	HYPH
cord-022561-rv5j1201	375	9	tinged	tinge	VBN
cord-022561-rv5j1201	375	10	plasma	plasma	NN
cord-022561-rv5j1201	375	11	or	or	CC
cord-022561-rv5j1201	375	12	serum	serum	NN
cord-022561-rv5j1201	375	13	,	,	,
cord-022561-rv5j1201	375	14	termed	termed	JJ
cord-022561-rv5j1201	375	15	hemolysis	hemolysis	NN
cord-022561-rv5j1201	375	16	or	or	CC
cord-022561-rv5j1201	375	17	hemoglobinemia	hemoglobinemia	NN
cord-022561-rv5j1201	375	18	.	.	.
cord-022561-rv5j1201	376	1	Hemolysis	Hemolysis	NNP
cord-022561-rv5j1201	376	2	is	be	VBZ
cord-022561-rv5j1201	376	3	not	not	RB
cord-022561-rv5j1201	376	4	apparent	apparent	JJ
cord-022561-rv5j1201	376	5	until	until	IN
cord-022561-rv5j1201	376	6	the	the	DT
cord-022561-rv5j1201	376	7	concentration	concentration	NN
cord-022561-rv5j1201	376	8	of	of	IN
cord-022561-rv5j1201	376	9	extracellular	extracellular	JJ
cord-022561-rv5j1201	376	10	hemoglobin	hemoglobin	NN
cord-022561-rv5j1201	376	11	is	be	VBZ
cord-022561-rv5j1201	376	12	greater	great	JJR
cord-022561-rv5j1201	376	13	than	than	IN
cord-022561-rv5j1201	376	14	approximately	approximately	RB
cord-022561-rv5j1201	376	15	50	50	CD
cord-022561-rv5j1201	376	16	mg	mg	NNS
cord-022561-rv5j1201	376	17	/	/	SYM
cord-022561-rv5j1201	376	18	dL.	dL.	NNP
cord-022561-rv5j1201	376	19	Cell	cell	NN
cord-022561-rv5j1201	376	20	-	-	HYPH
cord-022561-rv5j1201	376	21	free	free	JJ
cord-022561-rv5j1201	376	22	hemoglobin	hemoglobin	NN
cord-022561-rv5j1201	376	23	is	be	VBZ
cord-022561-rv5j1201	376	24	scavenged	scavenge	VBN
cord-022561-rv5j1201	376	25	by	by	IN
cord-022561-rv5j1201	376	26	haptoglobin	haptoglobin	NN
cord-022561-rv5j1201	376	27	until	until	IN
cord-022561-rv5j1201	376	28	haptoglobin	haptoglobin	NN
cord-022561-rv5j1201	376	29	becomes	become	VBZ
cord-022561-rv5j1201	376	30	saturated	saturate	VBN
cord-022561-rv5j1201	376	31	with	with	IN
cord-022561-rv5j1201	376	32	hemoglobin	hemoglobin	NN
cord-022561-rv5j1201	376	33	at	at	IN
cord-022561-rv5j1201	376	34	a	a	DT
cord-022561-rv5j1201	376	35	concentration	concentration	NN
cord-022561-rv5j1201	376	36	of	of	IN
cord-022561-rv5j1201	376	37	approximately	approximately	RB
cord-022561-rv5j1201	376	38	150	150	CD
cord-022561-rv5j1201	376	39	mg	mg	NNS
cord-022561-rv5j1201	376	40	/	/	SYM
cord-022561-rv5j1201	376	41	dL.	dL.	NNS
cord-022561-rv5j1201	377	1	When	when	WRB
cord-022561-rv5j1201	377	2	haptoglobin	haptoglobin	NN
cord-022561-rv5j1201	377	3	is	be	VBZ
cord-022561-rv5j1201	377	4	saturated	saturate	VBN
cord-022561-rv5j1201	377	5	,	,	,
cord-022561-rv5j1201	377	6	any	any	DT
cord-022561-rv5j1201	377	7	remaining	remain	VBG
cord-022561-rv5j1201	377	8	free	free	JJ
cord-022561-rv5j1201	377	9	hemoglobin	hemoglobin	NN
cord-022561-rv5j1201	377	10	has	have	VBZ
cord-022561-rv5j1201	377	11	a	a	DT
cord-022561-rv5j1201	377	12	low	low	JJ
cord-022561-rv5j1201	377	13	enough	enough	JJ
cord-022561-rv5j1201	377	14	molecular	molecular	JJ
cord-022561-rv5j1201	377	15	weight	weight	NN
cord-022561-rv5j1201	377	16	to	to	TO
cord-022561-rv5j1201	377	17	pass	pass	VB
cord-022561-rv5j1201	377	18	through	through	IN
cord-022561-rv5j1201	377	19	the	the	DT
cord-022561-rv5j1201	377	20	renal	renal	JJ
cord-022561-rv5j1201	377	21	glomerular	glomerular	JJ
cord-022561-rv5j1201	377	22	filter	filter	NN
cord-022561-rv5j1201	377	23	into	into	IN
cord-022561-rv5j1201	377	24	the	the	DT
cord-022561-rv5j1201	377	25	urine	urine	NN
cord-022561-rv5j1201	377	26	.	.	.
cord-022561-rv5j1201	378	1	This	this	DT
cord-022561-rv5j1201	378	2	imparts	impart	VBZ
cord-022561-rv5j1201	378	3	a	a	DT
cord-022561-rv5j1201	378	4	pink	pink	JJ
cord-022561-rv5j1201	378	5	or	or	CC
cord-022561-rv5j1201	378	6	red	red	JJ
cord-022561-rv5j1201	378	7	discoloration	discoloration	NN
cord-022561-rv5j1201	378	8	to	to	IN
cord-022561-rv5j1201	378	9	the	the	DT
cord-022561-rv5j1201	378	10	urine	urine	NN
cord-022561-rv5j1201	378	11	,	,	,
cord-022561-rv5j1201	378	12	called	call	VBN
cord-022561-rv5j1201	378	13	hemoglobinuria	hemoglobinuria	NNP
cord-022561-rv5j1201	378	14	.	.	.
cord-022561-rv5j1201	379	1	Thus	thus	RB
cord-022561-rv5j1201	379	2	extracellular	extracellular	JJ
cord-022561-rv5j1201	379	3	hemoglobin	hemoglobin	NN
cord-022561-rv5j1201	379	4	can	can	MD
cord-022561-rv5j1201	379	5	cause	cause	VB
cord-022561-rv5j1201	379	6	gross	gross	JJ
cord-022561-rv5j1201	379	7	discoloration	discoloration	NN
cord-022561-rv5j1201	379	8	of	of	IN
cord-022561-rv5j1201	379	9	the	the	DT
cord-022561-rv5j1201	379	10	plasma	plasma	NN
cord-022561-rv5j1201	379	11	,	,	,
cord-022561-rv5j1201	379	12	where	where	WRB
cord-022561-rv5j1201	379	13	it	-PRON-	PRP
cord-022561-rv5j1201	379	14	is	be	VBZ
cord-022561-rv5j1201	379	15	bound	bind	VBN
cord-022561-rv5j1201	379	16	to	to	IN
cord-022561-rv5j1201	379	17	haptoglobin	haptoglobin	NN
cord-022561-rv5j1201	379	18	,	,	,
cord-022561-rv5j1201	379	19	before	before	IN
cord-022561-rv5j1201	379	20	becoming	become	VBG
cord-022561-rv5j1201	379	21	grossly	grossly	RB
cord-022561-rv5j1201	379	22	visible	visible	JJ
cord-022561-rv5j1201	379	23	in	in	IN
cord-022561-rv5j1201	379	24	urine	urine	NN
cord-022561-rv5j1201	379	25	.	.	.
cord-022561-rv5j1201	380	1	The	the	DT
cord-022561-rv5j1201	380	2	half	half	JJ
cord-022561-rv5j1201	380	3	-	-	HYPH
cord-022561-rv5j1201	380	4	life	life	NN
cord-022561-rv5j1201	380	5	of	of	IN
cord-022561-rv5j1201	380	6	haptoglobin	haptoglobin	NN
cord-022561-rv5j1201	380	7	is	be	VBZ
cord-022561-rv5j1201	380	8	markedly	markedly	RB
cord-022561-rv5j1201	380	9	decreased	decrease	VBN
cord-022561-rv5j1201	380	10	when	when	WRB
cord-022561-rv5j1201	380	11	bound	bind	VBN
cord-022561-rv5j1201	380	12	to	to	IN
cord-022561-rv5j1201	380	13	hemoglobin	hemoglobin	NN
cord-022561-rv5j1201	380	14	,	,	,
cord-022561-rv5j1201	380	15	so	so	CC
cord-022561-rv5j1201	380	16	when	when	WRB
cord-022561-rv5j1201	380	17	large	large	JJ
cord-022561-rv5j1201	380	18	amounts	amount	NNS
cord-022561-rv5j1201	380	19	of	of	IN
cord-022561-rv5j1201	380	20	haptoglobin	haptoglobin	NN
cord-022561-rv5j1201	380	21	-	-	HYPH
cord-022561-rv5j1201	380	22	hemoglobin	hemoglobin	NN
cord-022561-rv5j1201	380	23	complex	complex	NN
cord-022561-rv5j1201	380	24	are	be	VBP
cord-022561-rv5j1201	380	25	formed	form	VBN
cord-022561-rv5j1201	380	26	,	,	,
cord-022561-rv5j1201	380	27	the	the	DT
cord-022561-rv5j1201	380	28	concentration	concentration	NN
cord-022561-rv5j1201	380	29	of	of	IN
cord-022561-rv5j1201	380	30	haptoglobin	haptoglobin	NN
cord-022561-rv5j1201	380	31	in	in	IN
cord-022561-rv5j1201	380	32	the	the	DT
cord-022561-rv5j1201	380	33	blood	blood	NN
cord-022561-rv5j1201	380	34	decreases	decrease	NNS
cord-022561-rv5j1201	380	35	and	and	CC
cord-022561-rv5j1201	380	36	hemoglobin	hemoglobin	NN
cord-022561-rv5j1201	380	37	can	can	MD
cord-022561-rv5j1201	380	38	pass	pass	VB
cord-022561-rv5j1201	380	39	through	through	IN
cord-022561-rv5j1201	380	40	the	the	DT
cord-022561-rv5j1201	380	41	glomerulus	glomerulus	NN
cord-022561-rv5j1201	380	42	at	at	IN
cord-022561-rv5j1201	380	43	even	even	RB
cord-022561-rv5j1201	380	44	lower	low	JJR
cord-022561-rv5j1201	380	45	concentrations	concentration	NNS
cord-022561-rv5j1201	380	46	.	.	.
cord-022561-rv5j1201	381	1	Hemoglobinuria	Hemoglobinuria	NNP
cord-022561-rv5j1201	381	2	is	be	VBZ
cord-022561-rv5j1201	381	3	a	a	DT
cord-022561-rv5j1201	381	4	contributing	contribute	VBG
cord-022561-rv5j1201	381	5	factor	factor	NN
cord-022561-rv5j1201	381	6	in	in	IN
cord-022561-rv5j1201	381	7	the	the	DT
cord-022561-rv5j1201	381	8	renal	renal	JJ
cord-022561-rv5j1201	381	9	tubular	tubular	JJ
cord-022561-rv5j1201	381	10	necrosis	necrosis	NN
cord-022561-rv5j1201	381	11	(	(	-LRB-
cord-022561-rv5j1201	381	12	hemoglobinuric	hemoglobinuric	NNP
cord-022561-rv5j1201	381	13	nephrosis	nephrosis	NNP
cord-022561-rv5j1201	381	14	)	)	-RRB-
cord-022561-rv5j1201	381	15	that	that	WDT
cord-022561-rv5j1201	381	16	often	often	RB
cord-022561-rv5j1201	381	17	occurs	occur	VBZ
cord-022561-rv5j1201	381	18	in	in	IN
cord-022561-rv5j1201	381	19	cases	case	NNS
cord-022561-rv5j1201	381	20	of	of	IN
cord-022561-rv5j1201	381	21	acute	acute	JJ
cord-022561-rv5j1201	381	22	intravascular	intravascular	JJ
cord-022561-rv5j1201	381	23	hemolysis	hemolysis	NN
cord-022561-rv5j1201	381	24	(	(	-LRB-
cord-022561-rv5j1201	381	25	see	see	VB
cord-022561-rv5j1201	381	26	Chapter	chapter	NN
cord-022561-rv5j1201	381	27	11	11	CD
cord-022561-rv5j1201	381	28	)	)	-RRB-
cord-022561-rv5j1201	381	29	.	.	.
cord-022561-rv5j1201	382	1	A	a	DT
cord-022561-rv5j1201	382	2	similar	similar	JJ
cord-022561-rv5j1201	382	3	lesion	lesion	NN
cord-022561-rv5j1201	382	4	occurs	occur	VBZ
cord-022561-rv5j1201	382	5	in	in	IN
cord-022561-rv5j1201	382	6	the	the	DT
cord-022561-rv5j1201	382	7	kidneys	kidney	NNS
cord-022561-rv5j1201	382	8	of	of	IN
cord-022561-rv5j1201	382	9	individuals	individual	NNS
cord-022561-rv5j1201	382	10	with	with	IN
cord-022561-rv5j1201	382	11	marked	marked	JJ
cord-022561-rv5j1201	382	12	muscle	muscle	NN
cord-022561-rv5j1201	382	13	damage	damage	NN
cord-022561-rv5j1201	382	14	and	and	CC
cord-022561-rv5j1201	382	15	resulting	result	VBG
cord-022561-rv5j1201	382	16	myoglobinuria	myoglobinuria	NNP
cord-022561-rv5j1201	382	17	(	(	-LRB-
cord-022561-rv5j1201	382	18	see	see	VB
cord-022561-rv5j1201	382	19	Chapters	chapter	NNS
cord-022561-rv5j1201	382	20	11	11	CD
cord-022561-rv5j1201	382	21	and	and	CC
cord-022561-rv5j1201	382	22	15	15	CD
cord-022561-rv5j1201	382	23	)	)	-RRB-
cord-022561-rv5j1201	382	24	.	.	.
cord-022561-rv5j1201	383	1	Hemoglobinuria	Hemoglobinuria	NNP
cord-022561-rv5j1201	383	2	can	can	MD
cord-022561-rv5j1201	383	3	not	not	RB
cord-022561-rv5j1201	383	4	be	be	VB
cord-022561-rv5j1201	383	5	distinguished	distinguish	VBN
cord-022561-rv5j1201	383	6	grossly	grossly	RB
cord-022561-rv5j1201	383	7	from	from	IN
cord-022561-rv5j1201	383	8	hematuria	hematuria	NN
cord-022561-rv5j1201	383	9	(	(	-LRB-
cord-022561-rv5j1201	383	10	erythrocytes	erythrocyte	NNS
cord-022561-rv5j1201	383	11	in	in	IN
cord-022561-rv5j1201	383	12	the	the	DT
cord-022561-rv5j1201	383	13	urine	urine	NN
cord-022561-rv5j1201	383	14	)	)	-RRB-
cord-022561-rv5j1201	383	15	or	or	CC
cord-022561-rv5j1201	383	16	myoglobinuria	myoglobinuria	FW
cord-022561-rv5j1201	383	17	(	(	-LRB-
cord-022561-rv5j1201	383	18	myoglobin	myoglobin	NN
cord-022561-rv5j1201	383	19	in	in	IN
cord-022561-rv5j1201	383	20	the	the	DT
cord-022561-rv5j1201	383	21	urine	urine	NN
cord-022561-rv5j1201	383	22	)	)	-RRB-
cord-022561-rv5j1201	383	23	,	,	,
cord-022561-rv5j1201	383	24	and	and	CC
cord-022561-rv5j1201	383	25	all	all	DT
cord-022561-rv5j1201	383	26	three	three	CD
cord-022561-rv5j1201	383	27	processes	process	NNS
cord-022561-rv5j1201	383	28	cause	cause	VBP
cord-022561-rv5j1201	383	29	a	a	DT
cord-022561-rv5j1201	383	30	positive	positive	JJ
cord-022561-rv5j1201	383	31	reaction	reaction	NN
cord-022561-rv5j1201	383	32	for	for	IN
cord-022561-rv5j1201	383	33	"	"	``
cord-022561-rv5j1201	383	34	blood	blood	NN
cord-022561-rv5j1201	383	35	protein	protein	NN
cord-022561-rv5j1201	383	36	"	"	''
cord-022561-rv5j1201	383	37	on	on	IN
cord-022561-rv5j1201	383	38	urine	urine	NN
cord-022561-rv5j1201	383	39	test	test	NN
cord-022561-rv5j1201	383	40	strips	strip	NNS
cord-022561-rv5j1201	383	41	.	.	.
cord-022561-rv5j1201	384	1	Comparing	compare	VBG
cord-022561-rv5j1201	384	2	the	the	DT
cord-022561-rv5j1201	384	3	colors	color	NNS
cord-022561-rv5j1201	384	4	of	of	IN
cord-022561-rv5j1201	384	5	the	the	DT
cord-022561-rv5j1201	384	6	plasma	plasma	NN
cord-022561-rv5j1201	384	7	and	and	CC
cord-022561-rv5j1201	384	8	the	the	DT
cord-022561-rv5j1201	384	9	urine	urine	NN
cord-022561-rv5j1201	384	10	may	may	MD
cord-022561-rv5j1201	384	11	be	be	VB
cord-022561-rv5j1201	384	12	informative	informative	JJ
cord-022561-rv5j1201	384	13	.	.	.
cord-022561-rv5j1201	385	1	In	in	IN
cord-022561-rv5j1201	385	2	contrast	contrast	NN
cord-022561-rv5j1201	385	3	to	to	IN
cord-022561-rv5j1201	385	4	hemoglobin	hemoglobin	NN
cord-022561-rv5j1201	385	5	,	,	,
cord-022561-rv5j1201	385	6	myoglobin	myoglobin	NN
cord-022561-rv5j1201	385	7	causes	cause	VBZ
cord-022561-rv5j1201	385	8	gross	gross	JJ
cord-022561-rv5j1201	385	9	discoloration	discoloration	NN
cord-022561-rv5j1201	385	10	of	of	IN
cord-022561-rv5j1201	385	11	the	the	DT
cord-022561-rv5j1201	385	12	urine	urine	NN
cord-022561-rv5j1201	385	13	before	before	IN
cord-022561-rv5j1201	385	14	the	the	DT
cord-022561-rv5j1201	385	15	plasma	plasma	NN
cord-022561-rv5j1201	385	16	is	be	VBZ
cord-022561-rv5j1201	385	17	discolored	discolored	JJ
cord-022561-rv5j1201	385	18	.	.	.
cord-022561-rv5j1201	386	1	This	this	DT
cord-022561-rv5j1201	386	2	is	be	VBZ
cord-022561-rv5j1201	386	3	because	because	IN
cord-022561-rv5j1201	386	4	myoglobin	myoglobin	NN
cord-022561-rv5j1201	386	5	is	be	VBZ
cord-022561-rv5j1201	386	6	a	a	DT
cord-022561-rv5j1201	386	7	low	low	JJ
cord-022561-rv5j1201	386	8	-	-	HYPH
cord-022561-rv5j1201	386	9	molecular	molecular	JJ
cord-022561-rv5j1201	386	10	-	-	HYPH
cord-022561-rv5j1201	386	11	weight	weight	NN
cord-022561-rv5j1201	386	12	monomer	monomer	NN
cord-022561-rv5j1201	386	13	,	,	,
cord-022561-rv5j1201	386	14	freely	freely	RB
cord-022561-rv5j1201	386	15	filtered	filter	VBN
cord-022561-rv5j1201	386	16	by	by	IN
cord-022561-rv5j1201	386	17	the	the	DT
cord-022561-rv5j1201	386	18	glomerulus	glomerulus	NN
cord-022561-rv5j1201	386	19	,	,	,
cord-022561-rv5j1201	386	20	and	and	CC
cord-022561-rv5j1201	386	21	does	do	VBZ
cord-022561-rv5j1201	386	22	not	not	RB
cord-022561-rv5j1201	386	23	bind	bind	VB
cord-022561-rv5j1201	386	24	plasma	plasma	NN
cord-022561-rv5j1201	386	25	proteins	protein	NNS
cord-022561-rv5j1201	386	26	to	to	IN
cord-022561-rv5j1201	386	27	a	a	DT
cord-022561-rv5j1201	386	28	significant	significant	JJ
cord-022561-rv5j1201	386	29	degree	degree	NN
cord-022561-rv5j1201	386	30	.	.	.
cord-022561-rv5j1201	387	1	Hematuria	Hematuria	NNP
cord-022561-rv5j1201	387	2	can	can	MD
cord-022561-rv5j1201	387	3	be	be	VB
cord-022561-rv5j1201	387	4	distinguished	distinguish	VBN
cord-022561-rv5j1201	387	5	from	from	IN
cord-022561-rv5j1201	387	6	hemoglobinuria	hemoglobinuria	NNP
cord-022561-rv5j1201	387	7	on	on	IN
cord-022561-rv5j1201	387	8	the	the	DT
cord-022561-rv5j1201	387	9	basis	basis	NN
cord-022561-rv5j1201	387	10	of	of	IN
cord-022561-rv5j1201	387	11	microscopic	microscopic	JJ
cord-022561-rv5j1201	387	12	examination	examination	NN
cord-022561-rv5j1201	387	13	of	of	IN
cord-022561-rv5j1201	387	14	urine	urine	NN
cord-022561-rv5j1201	387	15	sediment	sediment	NN
cord-022561-rv5j1201	387	16	(	(	-LRB-
cord-022561-rv5j1201	387	17	i.e.	i.e.	FW
cord-022561-rv5j1201	387	18	,	,	,
cord-022561-rv5j1201	387	19	erythrocytes	erythrocyte	NNS
cord-022561-rv5j1201	387	20	are	be	VBP
cord-022561-rv5j1201	387	21	present	present	JJ
cord-022561-rv5j1201	387	22	in	in	IN
cord-022561-rv5j1201	387	23	cases	case	NNS
cord-022561-rv5j1201	387	24	of	of	IN
cord-022561-rv5j1201	387	25	hematuria	hematuria	NN
cord-022561-rv5j1201	387	26	)	)	-RRB-
cord-022561-rv5j1201	387	27	.	.	.
cord-022561-rv5j1201	388	1	In	in	IN
cord-022561-rv5j1201	388	2	addition	addition	NN
cord-022561-rv5j1201	388	3	to	to	IN
cord-022561-rv5j1201	388	4	red	red	JJ
cord-022561-rv5j1201	388	5	plasma	plasma	NN
cord-022561-rv5j1201	388	6	and	and	CC
cord-022561-rv5j1201	388	7	urine	urine	NN
cord-022561-rv5j1201	388	8	,	,	,
cord-022561-rv5j1201	388	9	hemoglobinemia	hemoglobinemia	NN
cord-022561-rv5j1201	388	10	may	may	MD
cord-022561-rv5j1201	388	11	also	also	RB
cord-022561-rv5j1201	388	12	be	be	VB
cord-022561-rv5j1201	388	13	identified	identify	VBN
cord-022561-rv5j1201	388	14	by	by	IN
cord-022561-rv5j1201	388	15	increased	increase	VBN
cord-022561-rv5j1201	388	16	MCH	MCH	NNP
cord-022561-rv5j1201	388	17	or	or	CC
cord-022561-rv5j1201	388	18	MCHC	MCHC	NNP
cord-022561-rv5j1201	388	19	values	value	NNS
cord-022561-rv5j1201	388	20	on	on	IN
cord-022561-rv5j1201	388	21	a	a	DT
cord-022561-rv5j1201	388	22	CBC	CBC	NNP
cord-022561-rv5j1201	388	23	.	.	.
cord-022561-rv5j1201	389	1	This	this	DT
cord-022561-rv5j1201	389	2	is	be	VBZ
cord-022561-rv5j1201	389	3	because	because	IN
cord-022561-rv5j1201	389	4	the	the	DT
cord-022561-rv5j1201	389	5	hemoglobin	hemoglobin	NN
cord-022561-rv5j1201	389	6	concentration	concentration	NN
cord-022561-rv5j1201	389	7	is	be	VBZ
cord-022561-rv5j1201	389	8	measured	measure	VBN
cord-022561-rv5j1201	389	9	by	by	IN
cord-022561-rv5j1201	389	10	lysing	lyse	VBG
cord-022561-rv5j1201	389	11	all	all	DT
cord-022561-rv5j1201	389	12	erythrocytes	erythrocyte	NNS
cord-022561-rv5j1201	389	13	in	in	IN
cord-022561-rv5j1201	389	14	the	the	DT
cord-022561-rv5j1201	389	15	sample	sample	NN
cord-022561-rv5j1201	389	16	and	and	CC
cord-022561-rv5j1201	389	17	then	then	RB
cord-022561-rv5j1201	389	18	measuring	measure	VBG
cord-022561-rv5j1201	389	19	the	the	DT
cord-022561-rv5j1201	389	20	total	total	JJ
cord-022561-rv5j1201	389	21	hemoglobin	hemoglobin	NN
cord-022561-rv5j1201	389	22	via	via	IN
cord-022561-rv5j1201	389	23	spectrophotometry	spectrophotometry	NN
cord-022561-rv5j1201	389	24	.	.	.
cord-022561-rv5j1201	390	1	By	by	IN
cord-022561-rv5j1201	390	2	this	this	DT
cord-022561-rv5j1201	390	3	method	method	NN
cord-022561-rv5j1201	390	4	,	,	,
cord-022561-rv5j1201	390	5	hemoglobin	hemoglobin	NN
cord-022561-rv5j1201	390	6	that	that	WDT
cord-022561-rv5j1201	390	7	originated	originate	VBD
cord-022561-rv5j1201	390	8	within	within	IN
cord-022561-rv5j1201	390	9	or	or	CC
cord-022561-rv5j1201	390	10	outside	outside	RB
cord-022561-rv5j1201	390	11	of	of	IN
cord-022561-rv5j1201	390	12	erythrocytes	erythrocyte	NNS
cord-022561-rv5j1201	390	13	is	be	VBZ
cord-022561-rv5j1201	390	14	measured	measure	VBN
cord-022561-rv5j1201	390	15	together	together	RB
cord-022561-rv5j1201	390	16	.	.	.
cord-022561-rv5j1201	391	1	However	however	RB
cord-022561-rv5j1201	391	2	,	,	,
cord-022561-rv5j1201	391	3	calculations	calculation	NNS
cord-022561-rv5j1201	391	4	for	for	IN
cord-022561-rv5j1201	391	5	MCH	MCH	NNP
cord-022561-rv5j1201	391	6	and	and	CC
cord-022561-rv5j1201	391	7	MCHC	MCHC	NNP
cord-022561-rv5j1201	391	8	,	,	,
cord-022561-rv5j1201	391	9	which	which	WDT
cord-022561-rv5j1201	391	10	include	include	VBP
cord-022561-rv5j1201	391	11	results	result	NNS
cord-022561-rv5j1201	391	12	for	for	IN
cord-022561-rv5j1201	391	13	the	the	DT
cord-022561-rv5j1201	391	14	hemoglobin	hemoglobin	NN
cord-022561-rv5j1201	391	15	and	and	CC
cord-022561-rv5j1201	391	16	red	red	JJ
cord-022561-rv5j1201	391	17	blood	blood	NN
cord-022561-rv5j1201	391	18	cell	cell	NN
cord-022561-rv5j1201	391	19	concentrations	concentration	NNS
cord-022561-rv5j1201	391	20	,	,	,
cord-022561-rv5j1201	391	21	assume	assume	VBP
cord-022561-rv5j1201	391	22	that	that	IN
cord-022561-rv5j1201	391	23	all	all	DT
cord-022561-rv5j1201	391	24	of	of	IN
cord-022561-rv5j1201	391	25	tosis	tosis	NN
cord-022561-rv5j1201	391	26	,	,	,
cord-022561-rv5j1201	391	27	or	or	CC
cord-022561-rv5j1201	391	28	their	-PRON-	PRP$
cord-022561-rv5j1201	391	29	numbers	number	NNS
cord-022561-rv5j1201	391	30	are	be	VBP
cord-022561-rv5j1201	391	31	high	high	JJ
cord-022561-rv5j1201	391	32	relative	relative	NN
cord-022561-rv5j1201	391	33	to	to	IN
cord-022561-rv5j1201	391	34	the	the	DT
cord-022561-rv5j1201	391	35	degree	degree	NN
cord-022561-rv5j1201	391	36	of	of	IN
cord-022561-rv5j1201	391	37	reticulocytosis	reticulocytosis	NNP
cord-022561-rv5j1201	391	38	,	,	,
cord-022561-rv5j1201	391	39	termed	term	VBD
cord-022561-rv5j1201	391	40	inappropriate	inappropriate	JJ
cord-022561-rv5j1201	391	41	metarubricytosis	metarubricytosis	NN
cord-022561-rv5j1201	391	42	.	.	.
cord-022561-rv5j1201	392	1	In	in	IN
cord-022561-rv5j1201	392	2	ruminants	ruminant	NNS
cord-022561-rv5j1201	392	3	,	,	,
cord-022561-rv5j1201	392	4	reticulocytosis	reticulocytosis	NNP
cord-022561-rv5j1201	392	5	is	be	VBZ
cord-022561-rv5j1201	392	6	often	often	RB
cord-022561-rv5j1201	392	7	accompanied	accompany	VBN
cord-022561-rv5j1201	392	8	by	by	IN
cord-022561-rv5j1201	392	9	basophilic	basophilic	NNP
cord-022561-rv5j1201	392	10	stippling	stippling	NN
cord-022561-rv5j1201	392	11	(	(	-LRB-
cord-022561-rv5j1201	392	12	Fig	Fig	NNP
cord-022561-rv5j1201	392	13	.	.	.
cord-022561-rv5j1201	392	14	13	13	CD
cord-022561-rv5j1201	392	15	-	-	SYM
cord-022561-rv5j1201	392	16	8	8	CD
cord-022561-rv5j1201	392	17	)	)	-RRB-
cord-022561-rv5j1201	392	18	.	.	.
cord-022561-rv5j1201	393	1	However	however	RB
cord-022561-rv5j1201	393	2	,	,	,
cord-022561-rv5j1201	393	3	like	like	IN
cord-022561-rv5j1201	393	4	metarubricytosis	metarubricytosis	NNP
cord-022561-rv5j1201	393	5	,	,	,
cord-022561-rv5j1201	393	6	basophilic	basophilic	NNP
cord-022561-rv5j1201	393	7	stippling	stippling	NN
cord-022561-rv5j1201	393	8	without	without	IN
cord-022561-rv5j1201	393	9	reticulocytosis	reticulocytosis	NNP
cord-022561-rv5j1201	393	10	is	be	VBZ
cord-022561-rv5j1201	393	11	concerning	concern	VBG
cord-022561-rv5j1201	393	12	for	for	IN
cord-022561-rv5j1201	393	13	lead	lead	JJ
cord-022561-rv5j1201	393	14	poisoning	poisoning	NN
cord-022561-rv5j1201	393	15	or	or	CC
cord-022561-rv5j1201	393	16	other	other	JJ
cord-022561-rv5j1201	393	17	causes	cause	NNS
cord-022561-rv5j1201	393	18	of	of	IN
cord-022561-rv5j1201	393	19	dyserythropoiesis	dyserythropoiesis	NN
cord-022561-rv5j1201	393	20	.	.	.
cord-022561-rv5j1201	394	1	Recall	recall	VB
cord-022561-rv5j1201	394	2	that	that	IN
cord-022561-rv5j1201	394	3	the	the	DT
cord-022561-rv5j1201	394	4	stimulus	stimulus	NN
cord-022561-rv5j1201	394	5	for	for	IN
cord-022561-rv5j1201	394	6	increased	increase	VBN
cord-022561-rv5j1201	394	7	erythropoiesis	erythropoiesis	NN
cord-022561-rv5j1201	394	8	is	be	VBZ
cord-022561-rv5j1201	394	9	increased	increase	VBN
cord-022561-rv5j1201	394	10	secretion	secretion	NN
cord-022561-rv5j1201	394	11	of	of	IN
cord-022561-rv5j1201	394	12	Epo	Epo	NNP
cord-022561-rv5j1201	394	13	in	in	IN
cord-022561-rv5j1201	394	14	response	response	NN
cord-022561-rv5j1201	394	15	to	to	IN
cord-022561-rv5j1201	394	16	tissue	tissue	NN
cord-022561-rv5j1201	394	17	hypoxia	hypoxia	NN
cord-022561-rv5j1201	394	18	.	.	.
cord-022561-rv5j1201	395	1	Although	although	IN
cord-022561-rv5j1201	395	2	the	the	DT
cord-022561-rv5j1201	395	3	action	action	NN
cord-022561-rv5j1201	395	4	of	of	IN
cord-022561-rv5j1201	395	5	Epo	Epo	NNP
cord-022561-rv5j1201	395	6	on	on	IN
cord-022561-rv5j1201	395	7	erythropoiesis	erythropoiesis	NN
cord-022561-rv5j1201	395	8	is	be	VBZ
cord-022561-rv5j1201	395	9	rapid	rapid	JJ
cord-022561-rv5j1201	395	10	,	,	,
cord-022561-rv5j1201	395	11	evidence	evidence	NN
cord-022561-rv5j1201	395	12	of	of	IN
cord-022561-rv5j1201	395	13	a	a	DT
cord-022561-rv5j1201	395	14	regenerative	regenerative	JJ
cord-022561-rv5j1201	395	15	response	response	NN
cord-022561-rv5j1201	395	16	is	be	VBZ
cord-022561-rv5j1201	395	17	not	not	RB
cord-022561-rv5j1201	395	18	immediately	immediately	RB
cord-022561-rv5j1201	395	19	apparent	apparent	JJ
cord-022561-rv5j1201	395	20	in	in	IN
cord-022561-rv5j1201	395	21	a	a	DT
cord-022561-rv5j1201	395	22	blood	blood	NN
cord-022561-rv5j1201	395	23	sample	sample	NN
cord-022561-rv5j1201	395	24	.	.	.
cord-022561-rv5j1201	396	1	One	one	CD
cord-022561-rv5j1201	396	2	of	of	IN
cord-022561-rv5j1201	396	3	the	the	DT
cord-022561-rv5j1201	396	4	main	main	JJ
cord-022561-rv5j1201	396	5	effects	effect	NNS
cord-022561-rv5j1201	396	6	of	of	IN
cord-022561-rv5j1201	396	7	Epo	Epo	NNP
cord-022561-rv5j1201	396	8	is	be	VBZ
cord-022561-rv5j1201	396	9	to	to	TO
cord-022561-rv5j1201	396	10	expand	expand	VB
cord-022561-rv5j1201	396	11	the	the	DT
cord-022561-rv5j1201	396	12	pool	pool	NN
cord-022561-rv5j1201	396	13	of	of	IN
cord-022561-rv5j1201	396	14	early	early	JJ
cord-022561-rv5j1201	396	15	-	-	HYPH
cord-022561-rv5j1201	396	16	stage	stage	NN
cord-022561-rv5j1201	396	17	erythroid	erythroid	NN
cord-022561-rv5j1201	396	18	precursors	precursor	NNS
cord-022561-rv5j1201	396	19	,	,	,
cord-022561-rv5j1201	396	20	and	and	CC
cord-022561-rv5j1201	396	21	it	-PRON-	PRP
cord-022561-rv5j1201	396	22	takes	take	VBZ
cord-022561-rv5j1201	396	23	time	time	NN
cord-022561-rv5j1201	396	24	for	for	IN
cord-022561-rv5j1201	396	25	these	these	DT
cord-022561-rv5j1201	396	26	cells	cell	NNS
cord-022561-rv5j1201	396	27	to	to	TO
cord-022561-rv5j1201	396	28	differentiate	differentiate	VB
cord-022561-rv5j1201	396	29	to	to	IN
cord-022561-rv5j1201	396	30	the	the	DT
cord-022561-rv5j1201	396	31	point	point	NN
cord-022561-rv5j1201	396	32	where	where	WRB
cord-022561-rv5j1201	396	33	they	-PRON-	PRP
cord-022561-rv5j1201	396	34	are	be	VBP
cord-022561-rv5j1201	396	35	released	release	VBN
cord-022561-rv5j1201	396	36	into	into	IN
cord-022561-rv5j1201	396	37	circulation	circulation	NN
cord-022561-rv5j1201	396	38	.	.	.
cord-022561-rv5j1201	397	1	In	in	IN
cord-022561-rv5j1201	397	2	a	a	DT
cord-022561-rv5j1201	397	3	case	case	NN
cord-022561-rv5j1201	397	4	of	of	IN
cord-022561-rv5j1201	397	5	acute	acute	JJ
cord-022561-rv5j1201	397	6	hemorrhage	hemorrhage	NN
cord-022561-rv5j1201	397	7	or	or	CC
cord-022561-rv5j1201	397	8	hemolysis	hemolysis	NN
cord-022561-rv5j1201	397	9	,	,	,
cord-022561-rv5j1201	397	10	for	for	IN
cord-022561-rv5j1201	397	11	example	example	NN
cord-022561-rv5j1201	397	12	,	,	,
cord-022561-rv5j1201	397	13	it	-PRON-	PRP
cord-022561-rv5j1201	397	14	typically	typically	RB
cord-022561-rv5j1201	397	15	takes	take	VBZ
cord-022561-rv5j1201	397	16	3	3	CD
cord-022561-rv5j1201	397	17	to	to	TO
cord-022561-rv5j1201	397	18	4	4	CD
cord-022561-rv5j1201	397	19	days	day	NNS
cord-022561-rv5j1201	397	20	until	until	IN
cord-022561-rv5j1201	397	21	reticulocytosis	reticulocytosis	NNP
cord-022561-rv5j1201	397	22	is	be	VBZ
cord-022561-rv5j1201	397	23	evident	evident	JJ
cord-022561-rv5j1201	397	24	on	on	IN
cord-022561-rv5j1201	397	25	the	the	DT
cord-022561-rv5j1201	397	26	CBC	CBC	NNP
cord-022561-rv5j1201	397	27	and	and	CC
cord-022561-rv5j1201	397	28	several	several	JJ
cord-022561-rv5j1201	397	29	more	more	JJR
cord-022561-rv5j1201	397	30	days	day	NNS
cord-022561-rv5j1201	397	31	until	until	IN
cord-022561-rv5j1201	397	32	the	the	DT
cord-022561-rv5j1201	397	33	regenerative	regenerative	JJ
cord-022561-rv5j1201	397	34	response	response	NN
cord-022561-rv5j1201	397	35	peaks	peak	NNS
cord-022561-rv5j1201	397	36	.	.	.
cord-022561-rv5j1201	398	1	The	the	DT
cord-022561-rv5j1201	398	2	term	term	NN
cord-022561-rv5j1201	398	3	preregenerative	preregenerative	JJ
cord-022561-rv5j1201	398	4	anemia	anemia	NN
cord-022561-rv5j1201	398	5	is	be	VBZ
cord-022561-rv5j1201	398	6	sometimes	sometimes	RB
cord-022561-rv5j1201	398	7	used	use	VBN
cord-022561-rv5j1201	398	8	to	to	TO
cord-022561-rv5j1201	398	9	describe	describe	VB
cord-022561-rv5j1201	398	10	anemia	anemia	NN
cord-022561-rv5j1201	398	11	with	with	IN
cord-022561-rv5j1201	398	12	a	a	DT
cord-022561-rv5j1201	398	13	regenerative	regenerative	JJ
cord-022561-rv5j1201	398	14	response	response	NN
cord-022561-rv5j1201	398	15	that	that	WDT
cord-022561-rv5j1201	398	16	is	be	VBZ
cord-022561-rv5j1201	398	17	impending	impending	JJ
cord-022561-rv5j1201	398	18	but	but	CC
cord-022561-rv5j1201	398	19	not	not	RB
cord-022561-rv5j1201	398	20	yet	yet	RB
cord-022561-rv5j1201	398	21	apparent	apparent	JJ
cord-022561-rv5j1201	398	22	on	on	IN
cord-022561-rv5j1201	398	23	the	the	DT
cord-022561-rv5j1201	398	24	CBC	CBC	NNP
cord-022561-rv5j1201	398	25	.	.	.
cord-022561-rv5j1201	399	1	Confirming	confirm	VBG
cord-022561-rv5j1201	399	2	a	a	DT
cord-022561-rv5j1201	399	3	regenerative	regenerative	JJ
cord-022561-rv5j1201	399	4	response	response	NN
cord-022561-rv5j1201	399	5	in	in	IN
cord-022561-rv5j1201	399	6	such	such	JJ
cord-022561-rv5j1201	399	7	cases	case	NNS
cord-022561-rv5j1201	399	8	requires	require	VBZ
cord-022561-rv5j1201	399	9	either	either	CC
cord-022561-rv5j1201	399	10	evidence	evidence	NN
cord-022561-rv5j1201	399	11	of	of	IN
cord-022561-rv5j1201	399	12	erythroid	erythroid	JJ
cord-022561-rv5j1201	399	13	hyperplasia	hyperplasia	NN
cord-022561-rv5j1201	399	14	in	in	IN
cord-022561-rv5j1201	399	15	the	the	DT
cord-022561-rv5j1201	399	16	bone	bone	NN
cord-022561-rv5j1201	399	17	marrow	marrow	NN
cord-022561-rv5j1201	399	18	or	or	CC
cord-022561-rv5j1201	399	19	emergence	emergence	NN
cord-022561-rv5j1201	399	20	of	of	IN
cord-022561-rv5j1201	399	21	a	a	DT
cord-022561-rv5j1201	399	22	reticulocytosis	reticulocytosis	NN
cord-022561-rv5j1201	399	23	on	on	IN
cord-022561-rv5j1201	399	24	subsequent	subsequent	JJ
cord-022561-rv5j1201	399	25	days	day	NNS
cord-022561-rv5j1201	399	26	.	.	.
cord-022561-rv5j1201	400	1	Hemorrhage	hemorrhage	NN
cord-022561-rv5j1201	400	2	results	result	NNS
cord-022561-rv5j1201	400	3	in	in	IN
cord-022561-rv5j1201	400	4	escape	escape	NN
cord-022561-rv5j1201	400	5	of	of	IN
cord-022561-rv5j1201	400	6	erythrocytes	erythrocyte	NNS
cord-022561-rv5j1201	400	7	and	and	CC
cord-022561-rv5j1201	400	8	other	other	JJ
cord-022561-rv5j1201	400	9	blood	blood	NN
cord-022561-rv5j1201	400	10	components	component	NNS
cord-022561-rv5j1201	400	11	,	,	,
cord-022561-rv5j1201	400	12	such	such	JJ
cord-022561-rv5j1201	400	13	as	as	IN
cord-022561-rv5j1201	400	14	protein	protein	NN
cord-022561-rv5j1201	400	15	,	,	,
cord-022561-rv5j1201	400	16	from	from	IN
cord-022561-rv5j1201	400	17	the	the	DT
cord-022561-rv5j1201	400	18	vasculature	vasculature	NN
cord-022561-rv5j1201	400	19	.	.	.
cord-022561-rv5j1201	401	1	As	as	IN
cord-022561-rv5j1201	401	2	a	a	DT
cord-022561-rv5j1201	401	3	result	result	NN
cord-022561-rv5j1201	401	4	,	,	,
cord-022561-rv5j1201	401	5	a	a	DT
cord-022561-rv5j1201	401	6	decreased	decrease	VBN
cord-022561-rv5j1201	401	7	plasma	plasma	NN
cord-022561-rv5j1201	401	8	or	or	CC
cord-022561-rv5j1201	401	9	serum	serum	NN
cord-022561-rv5j1201	401	10	protein	protein	NN
cord-022561-rv5j1201	401	11	concentration	concentration	NN
cord-022561-rv5j1201	401	12	,	,	,
cord-022561-rv5j1201	401	13	termed	term	VBD
cord-022561-rv5j1201	401	14	hypoproteinemia	hypoproteinemia	NN
cord-022561-rv5j1201	401	15	,	,	,
cord-022561-rv5j1201	401	16	may	may	MD
cord-022561-rv5j1201	401	17	be	be	VB
cord-022561-rv5j1201	401	18	evident	evident	JJ
cord-022561-rv5j1201	401	19	on	on	IN
cord-022561-rv5j1201	401	20	a	a	DT
cord-022561-rv5j1201	401	21	CBC	CBC	NNP
cord-022561-rv5j1201	401	22	or	or	CC
cord-022561-rv5j1201	401	23	chemistry	chemistry	NN
cord-022561-rv5j1201	401	24	panel	panel	NN
cord-022561-rv5j1201	401	25	.	.	.
cord-022561-rv5j1201	402	1	If	if	IN
cord-022561-rv5j1201	402	2	the	the	DT
cord-022561-rv5j1201	402	3	hemorrhage	hemorrhage	NN
cord-022561-rv5j1201	402	4	is	be	VBZ
cord-022561-rv5j1201	402	5	into	into	IN
cord-022561-rv5j1201	402	6	the	the	DT
cord-022561-rv5j1201	402	7	gastrointestinal	gastrointestinal	JJ
cord-022561-rv5j1201	402	8	lumen	lumen	NN
cord-022561-rv5j1201	402	9	,	,	,
cord-022561-rv5j1201	402	10	some	some	DT
cord-022561-rv5j1201	402	11	of	of	IN
cord-022561-rv5j1201	402	12	the	the	DT
cord-022561-rv5j1201	402	13	protein	protein	NN
cord-022561-rv5j1201	402	14	may	may	MD
cord-022561-rv5j1201	402	15	be	be	VB
cord-022561-rv5j1201	402	16	resorbed	resorb	VBN
cord-022561-rv5j1201	402	17	and	and	CC
cord-022561-rv5j1201	402	18	converted	convert	VBN
cord-022561-rv5j1201	402	19	to	to	IN
cord-022561-rv5j1201	402	20	urea	urea	NN
cord-022561-rv5j1201	402	21	,	,	,
cord-022561-rv5j1201	402	22	resulting	result	VBG
cord-022561-rv5j1201	402	23	in	in	IN
cord-022561-rv5j1201	402	24	an	an	DT
cord-022561-rv5j1201	402	25	increased	increase	VBN
cord-022561-rv5j1201	402	26	urea	urea	NN
cord-022561-rv5j1201	402	27	nitrogen	nitrogen	NN
cord-022561-rv5j1201	402	28	concentration	concentration	NN
cord-022561-rv5j1201	402	29	relative	relative	JJ
cord-022561-rv5j1201	402	30	to	to	IN
cord-022561-rv5j1201	402	31	creatinine	creatinine	NN
cord-022561-rv5j1201	402	32	in	in	IN
cord-022561-rv5j1201	402	33	plasma	plasma	NN
cord-022561-rv5j1201	402	34	.	.	.
cord-022561-rv5j1201	403	1	Hemorrhage	hemorrhage	NN
cord-022561-rv5j1201	403	2	within	within	IN
cord-022561-rv5j1201	403	3	the	the	DT
cord-022561-rv5j1201	403	4	urinary	urinary	JJ
cord-022561-rv5j1201	403	5	tract	tract	NN
cord-022561-rv5j1201	403	6	may	may	MD
cord-022561-rv5j1201	403	7	cause	cause	VB
cord-022561-rv5j1201	403	8	red	red	JJ
cord-022561-rv5j1201	403	9	urine	urine	NN
cord-022561-rv5j1201	403	10	with	with	IN
cord-022561-rv5j1201	403	11	erythrocytes	erythrocyte	NNS
cord-022561-rv5j1201	403	12	observed	observe	VBN
cord-022561-rv5j1201	403	13	in	in	IN
cord-022561-rv5j1201	403	14	the	the	DT
cord-022561-rv5j1201	403	15	urine	urine	NN
cord-022561-rv5j1201	403	16	sediment	sediment	NN
cord-022561-rv5j1201	403	17	.	.	.
cord-022561-rv5j1201	404	1	Causes	cause	NNS
cord-022561-rv5j1201	404	2	of	of	IN
cord-022561-rv5j1201	404	3	hemorrhage	hemorrhage	NN
cord-022561-rv5j1201	404	4	include	include	VBP
cord-022561-rv5j1201	404	5	trauma	trauma	NN
cord-022561-rv5j1201	404	6	,	,	,
cord-022561-rv5j1201	404	7	abnormal	abnormal	JJ
cord-022561-rv5j1201	404	8	hemostasis	hemostasis	NN
cord-022561-rv5j1201	404	9	,	,	,
cord-022561-rv5j1201	404	10	certain	certain	JJ
cord-022561-rv5j1201	404	11	parasitisms	parasitism	NNS
cord-022561-rv5j1201	404	12	,	,	,
cord-022561-rv5j1201	404	13	ulceration	ulceration	NN
cord-022561-rv5j1201	404	14	,	,	,
cord-022561-rv5j1201	404	15	and	and	CC
cord-022561-rv5j1201	404	16	neoplasia	neoplasia	NN
cord-022561-rv5j1201	404	17	.	.	.
cord-022561-rv5j1201	405	1	Hemorrhage	hemorrhage	NN
cord-022561-rv5j1201	405	2	may	may	MD
cord-022561-rv5j1201	405	3	be	be	VB
cord-022561-rv5j1201	405	4	acute	acute	JJ
cord-022561-rv5j1201	405	5	or	or	CC
cord-022561-rv5j1201	405	6	chronic	chronic	JJ
cord-022561-rv5j1201	405	7	,	,	,
cord-022561-rv5j1201	405	8	or	or	CC
cord-022561-rv5j1201	405	9	internal	internal	JJ
cord-022561-rv5j1201	405	10	or	or	CC
cord-022561-rv5j1201	405	11	external	external	JJ
cord-022561-rv5j1201	405	12	.	.	.
cord-022561-rv5j1201	406	1	During	during	IN
cord-022561-rv5j1201	406	2	acute	acute	JJ
cord-022561-rv5j1201	406	3	hemorrhage	hemorrhage	NN
cord-022561-rv5j1201	406	4	,	,	,
cord-022561-rv5j1201	406	5	there	there	EX
cord-022561-rv5j1201	406	6	are	be	VBP
cord-022561-rv5j1201	406	7	ample	ample	JJ
cord-022561-rv5j1201	406	8	iron	iron	NN
cord-022561-rv5j1201	406	9	stores	store	NNS
cord-022561-rv5j1201	406	10	within	within	IN
cord-022561-rv5j1201	406	11	the	the	DT
cord-022561-rv5j1201	406	12	body	body	NN
cord-022561-rv5j1201	406	13	for	for	IN
cord-022561-rv5j1201	406	14	hemoglobin	hemoglobin	NN
cord-022561-rv5j1201	406	15	synthesis	synthesis	NN
cord-022561-rv5j1201	406	16	and	and	CC
cord-022561-rv5j1201	406	17	erythrocyte	erythrocyte	NN
cord-022561-rv5j1201	406	18	regeneration	regeneration	NN
cord-022561-rv5j1201	406	19	.	.	.
cord-022561-rv5j1201	407	1	However	however	RB
cord-022561-rv5j1201	407	2	,	,	,
cord-022561-rv5j1201	407	3	with	with	IN
cord-022561-rv5j1201	407	4	chronic	chronic	JJ
cord-022561-rv5j1201	407	5	external	external	JJ
cord-022561-rv5j1201	407	6	hemorrhage	hemorrhage	NN
cord-022561-rv5j1201	407	7	,	,	,
cord-022561-rv5j1201	407	8	continued	continue	VBN
cord-022561-rv5j1201	407	9	loss	loss	NN
cord-022561-rv5j1201	407	10	of	of	IN
cord-022561-rv5j1201	407	11	iron	iron	NN
cord-022561-rv5j1201	407	12	may	may	MD
cord-022561-rv5j1201	407	13	deplete	deplete	VB
cord-022561-rv5j1201	407	14	the	the	DT
cord-022561-rv5j1201	407	15	body	body	NN
cord-022561-rv5j1201	407	16	's	's	POS
cord-022561-rv5j1201	407	17	iron	iron	NN
cord-022561-rv5j1201	407	18	stores	store	NNS
cord-022561-rv5j1201	407	19	.	.	.
cord-022561-rv5j1201	408	1	As	as	IN
cord-022561-rv5j1201	408	2	iron	iron	NN
cord-022561-rv5j1201	408	3	stores	store	NNS
cord-022561-rv5j1201	408	4	diminish	diminish	VBP
cord-022561-rv5j1201	408	5	,	,	,
cord-022561-rv5j1201	408	6	so	so	RB
cord-022561-rv5j1201	408	7	does	do	VBZ
cord-022561-rv5j1201	408	8	erythrocyte	erythrocyte	NN
cord-022561-rv5j1201	408	9	regeneration	regeneration	NN
cord-022561-rv5j1201	408	10	,	,	,
cord-022561-rv5j1201	408	11	eventually	eventually	RB
cord-022561-rv5j1201	408	12	leading	lead	VBG
cord-022561-rv5j1201	408	13	to	to	IN
cord-022561-rv5j1201	408	14	iron	iron	NN
cord-022561-rv5j1201	408	15	deficiency	deficiency	NN
cord-022561-rv5j1201	408	16	anemia	anemia	NN
cord-022561-rv5j1201	408	17	.	.	.
cord-022561-rv5j1201	409	1	Iron	iron	NN
cord-022561-rv5j1201	409	2	deficiency	deficiency	NN
cord-022561-rv5j1201	409	3	anemia	anemia	NN
cord-022561-rv5j1201	409	4	is	be	VBZ
cord-022561-rv5j1201	409	5	either	either	CC
cord-022561-rv5j1201	409	6	poorly	poorly	RB
cord-022561-rv5j1201	409	7	regenerative	regenerative	JJ
cord-022561-rv5j1201	409	8	or	or	CC
cord-022561-rv5j1201	409	9	nonregenerative	nonregenerative	JJ
cord-022561-rv5j1201	409	10	and	and	CC
cord-022561-rv5j1201	409	11	is	be	VBZ
cord-022561-rv5j1201	409	12	discussed	discuss	VBN
cord-022561-rv5j1201	409	13	in	in	IN
cord-022561-rv5j1201	409	14	more	more	JJR
cord-022561-rv5j1201	409	15	detail	detail	NN
cord-022561-rv5j1201	409	16	later	later	RB
cord-022561-rv5j1201	409	17	in	in	IN
cord-022561-rv5j1201	409	18	the	the	DT
cord-022561-rv5j1201	409	19	chapter	chapter	NN
cord-022561-rv5j1201	409	20	.	.	.
cord-022561-rv5j1201	410	1	Iron	iron	NN
cord-022561-rv5j1201	410	2	deficiency	deficiency	NN
cord-022561-rv5j1201	410	3	anemia	anemia	NN
cord-022561-rv5j1201	410	4	does	do	VBZ
cord-022561-rv5j1201	410	5	not	not	RB
cord-022561-rv5j1201	410	6	occur	occur	VB
cord-022561-rv5j1201	410	7	with	with	IN
cord-022561-rv5j1201	410	8	chronic	chronic	JJ
cord-022561-rv5j1201	410	9	internal	internal	JJ
cord-022561-rv5j1201	410	10	hemorrhage	hemorrhage	NN
cord-022561-rv5j1201	410	11	,	,	,
cord-022561-rv5j1201	410	12	Spherocytes	Spherocytes	NNPS
cord-022561-rv5j1201	410	13	form	form	NN
cord-022561-rv5j1201	410	14	when	when	WRB
cord-022561-rv5j1201	410	15	macrophages	macrophage	NNS
cord-022561-rv5j1201	410	16	(	(	-LRB-
cord-022561-rv5j1201	410	17	mainly	mainly	RB
cord-022561-rv5j1201	410	18	in	in	IN
cord-022561-rv5j1201	410	19	the	the	DT
cord-022561-rv5j1201	410	20	spleen	spleen	NN
cord-022561-rv5j1201	410	21	)	)	-RRB-
cord-022561-rv5j1201	410	22	phagocytize	phagocytize	NNP
cord-022561-rv5j1201	410	23	part	part	NN
cord-022561-rv5j1201	410	24	of	of	IN
cord-022561-rv5j1201	410	25	an	an	DT
cord-022561-rv5j1201	410	26	erythrocyte	erythrocyte	NN
cord-022561-rv5j1201	410	27	plasma	plasma	NN
cord-022561-rv5j1201	410	28	membrane	membrane	NN
cord-022561-rv5j1201	410	29	bound	bind	VBN
cord-022561-rv5j1201	410	30	with	with	IN
cord-022561-rv5j1201	410	31	autoantibody	autoantibody	NNP
cord-022561-rv5j1201	411	1	(	(	-LRB-
cord-022561-rv5j1201	411	2	Fig	Fig	NNP
cord-022561-rv5j1201	411	3	.	.	.
cord-022561-rv5j1201	411	4	13	13	CD
cord-022561-rv5j1201	411	5	-	-	SYM
cord-022561-rv5j1201	411	6	12	12	CD
cord-022561-rv5j1201	411	7	)	)	-RRB-
cord-022561-rv5j1201	411	8	.	.	.
cord-022561-rv5j1201	412	1	The	the	DT
cord-022561-rv5j1201	412	2	remaining	remain	VBG
cord-022561-rv5j1201	412	3	portion	portion	NN
cord-022561-rv5j1201	412	4	of	of	IN
cord-022561-rv5j1201	412	5	the	the	DT
cord-022561-rv5j1201	412	6	erythrocyte	erythrocyte	NN
cord-022561-rv5j1201	412	7	assumes	assume	VBZ
cord-022561-rv5j1201	412	8	a	a	DT
cord-022561-rv5j1201	412	9	spherical	spherical	JJ
cord-022561-rv5j1201	412	10	shape	shape	NN
cord-022561-rv5j1201	412	11	,	,	,
cord-022561-rv5j1201	412	12	thus	thus	RB
cord-022561-rv5j1201	412	13	preserving	preserve	VBG
cord-022561-rv5j1201	412	14	maximal	maximal	JJ
cord-022561-rv5j1201	412	15	volume	volume	NN
cord-022561-rv5j1201	412	16	.	.	.
cord-022561-rv5j1201	413	1	This	this	DT
cord-022561-rv5j1201	413	2	change	change	NN
cord-022561-rv5j1201	413	3	in	in	IN
cord-022561-rv5j1201	413	4	shape	shape	NN
cord-022561-rv5j1201	413	5	results	result	NNS
cord-022561-rv5j1201	413	6	in	in	IN
cord-022561-rv5j1201	413	7	decreased	decrease	VBN
cord-022561-rv5j1201	413	8	deformability	deformability	NN
cord-022561-rv5j1201	413	9	of	of	IN
cord-022561-rv5j1201	413	10	the	the	DT
cord-022561-rv5j1201	413	11	cells	cell	NNS
cord-022561-rv5j1201	413	12	.	.	.
cord-022561-rv5j1201	414	1	Erythrocytes	erythrocyte	NNS
cord-022561-rv5j1201	414	2	must	must	MD
cord-022561-rv5j1201	414	3	be	be	VB
cord-022561-rv5j1201	414	4	extremely	extremely	RB
cord-022561-rv5j1201	414	5	pliable	pliable	JJ
cord-022561-rv5j1201	414	6	to	to	TO
cord-022561-rv5j1201	414	7	traverse	traverse	VB
cord-022561-rv5j1201	414	8	the	the	DT
cord-022561-rv5j1201	414	9	splenic	splenic	JJ
cord-022561-rv5j1201	414	10	red	red	JJ
cord-022561-rv5j1201	414	11	pulp	pulp	NN
cord-022561-rv5j1201	414	12	and	and	CC
cord-022561-rv5j1201	414	13	sinusoidal	sinusoidal	JJ
cord-022561-rv5j1201	414	14	walls	wall	NNS
cord-022561-rv5j1201	414	15	;	;	:
cord-022561-rv5j1201	414	16	spherocytes	spherocyte	NNS
cord-022561-rv5j1201	414	17	therefore	therefore	RB
cord-022561-rv5j1201	414	18	tend	tend	VBP
cord-022561-rv5j1201	414	19	to	to	TO
cord-022561-rv5j1201	414	20	be	be	VB
cord-022561-rv5j1201	414	21	retained	retain	VBN
cord-022561-rv5j1201	414	22	in	in	IN
cord-022561-rv5j1201	414	23	the	the	DT
cord-022561-rv5j1201	414	24	spleen	spleen	NNS
cord-022561-rv5j1201	414	25	in	in	IN
cord-022561-rv5j1201	414	26	close	close	JJ
cord-022561-rv5j1201	414	27	association	association	NN
cord-022561-rv5j1201	414	28	with	with	IN
cord-022561-rv5j1201	414	29	macrophages	macrophage	NNS
cord-022561-rv5j1201	414	30	with	with	IN
cord-022561-rv5j1201	414	31	risk	risk	NN
cord-022561-rv5j1201	414	32	for	for	IN
cord-022561-rv5j1201	414	33	further	further	JJ
cord-022561-rv5j1201	414	34	injury	injury	NN
cord-022561-rv5j1201	414	35	and	and	CC
cord-022561-rv5j1201	414	36	eventual	eventual	JJ
cord-022561-rv5j1201	414	37	destruction	destruction	NN
cord-022561-rv5j1201	414	38	.	.	.
cord-022561-rv5j1201	415	1	In	in	IN
cord-022561-rv5j1201	415	2	the	the	DT
cord-022561-rv5j1201	415	3	dog	dog	NN
cord-022561-rv5j1201	415	4	,	,	,
cord-022561-rv5j1201	415	5	spherocytes	spherocyte	NNS
cord-022561-rv5j1201	415	6	appear	appear	VBP
cord-022561-rv5j1201	415	7	smaller	small	JJR
cord-022561-rv5j1201	415	8	than	than	IN
cord-022561-rv5j1201	415	9	normal	normal	JJ
cord-022561-rv5j1201	415	10	and	and	CC
cord-022561-rv5j1201	415	11	have	have	VBP
cord-022561-rv5j1201	415	12	uniform	uniform	JJ
cord-022561-rv5j1201	415	13	staining	staining	NN
cord-022561-rv5j1201	415	14	(	(	-LRB-
cord-022561-rv5j1201	415	15	Fig	Fig	NNP
cord-022561-rv5j1201	415	16	.	.	.
cord-022561-rv5j1201	415	17	13	13	CD
cord-022561-rv5j1201	415	18	-	-	SYM
cord-022561-rv5j1201	415	19	13	13	CD
cord-022561-rv5j1201	415	20	,	,	,
cord-022561-rv5j1201	415	21	A	A	NNP
cord-022561-rv5j1201	415	22	)	)	-RRB-
cord-022561-rv5j1201	415	23	,	,	,
cord-022561-rv5j1201	415	24	in	in	IN
cord-022561-rv5j1201	415	25	contrast	contrast	NN
cord-022561-rv5j1201	415	26	to	to	IN
cord-022561-rv5j1201	415	27	normal	normal	JJ
cord-022561-rv5j1201	415	28	erythrocytes	erythrocyte	NNS
cord-022561-rv5j1201	415	29	,	,	,
cord-022561-rv5j1201	415	30	which	which	WDT
cord-022561-rv5j1201	415	31	have	have	VBP
cord-022561-rv5j1201	415	32	a	a	DT
cord-022561-rv5j1201	415	33	region	region	NN
cord-022561-rv5j1201	415	34	of	of	IN
cord-022561-rv5j1201	415	35	central	central	JJ
cord-022561-rv5j1201	415	36	pallor	pallor	NN
cord-022561-rv5j1201	415	37	imparted	impart	VBN
cord-022561-rv5j1201	415	38	by	by	IN
cord-022561-rv5j1201	415	39	their	-PRON-	PRP$
cord-022561-rv5j1201	415	40	biconcave	biconcave	NN
cord-022561-rv5j1201	415	41	shape	shape	NN
cord-022561-rv5j1201	415	42	.	.	.
cord-022561-rv5j1201	416	1	This	this	DT
cord-022561-rv5j1201	416	2	difference	difference	NN
cord-022561-rv5j1201	416	3	in	in	IN
cord-022561-rv5j1201	416	4	staining	stain	VBG
cord-022561-rv5j1201	416	5	between	between	IN
cord-022561-rv5j1201	416	6	spherocytes	spherocyte	NNS
cord-022561-rv5j1201	416	7	and	and	CC
cord-022561-rv5j1201	416	8	normal	normal	JJ
cord-022561-rv5j1201	416	9	erythrocytes	erythrocyte	NNS
cord-022561-rv5j1201	416	10	is	be	VBZ
cord-022561-rv5j1201	416	11	not	not	RB
cord-022561-rv5j1201	416	12	consistently	consistently	RB
cord-022561-rv5j1201	416	13	discernible	discernible	JJ
cord-022561-rv5j1201	416	14	in	in	IN
cord-022561-rv5j1201	416	15	many	many	JJ
cord-022561-rv5j1201	416	16	other	other	JJ
cord-022561-rv5j1201	416	17	domestic	domestic	JJ
cord-022561-rv5j1201	416	18	animals	animal	NNS
cord-022561-rv5j1201	416	19	(	(	-LRB-
cord-022561-rv5j1201	416	20	including	include	VBG
cord-022561-rv5j1201	416	21	horses	horse	NNS
cord-022561-rv5j1201	416	22	,	,	,
cord-022561-rv5j1201	416	23	the	the	DT
cord-022561-rv5j1201	416	24	hemoglobin	hemoglobin	NN
cord-022561-rv5j1201	416	25	originated	originate	VBD
cord-022561-rv5j1201	416	26	within	within	IN
cord-022561-rv5j1201	416	27	erythrocytes	erythrocyte	NNS
cord-022561-rv5j1201	416	28	.	.	.
cord-022561-rv5j1201	417	1	In	in	IN
cord-022561-rv5j1201	417	2	the	the	DT
cord-022561-rv5j1201	417	3	case	case	NN
cord-022561-rv5j1201	417	4	of	of	IN
cord-022561-rv5j1201	417	5	hemoglobinemia	hemoglobinemia	NNP
cord-022561-rv5j1201	417	6	,	,	,
cord-022561-rv5j1201	417	7	the	the	DT
cord-022561-rv5j1201	417	8	excess	excess	JJ
cord-022561-rv5j1201	417	9	extracellular	extracellular	JJ
cord-022561-rv5j1201	417	10	hemoglobin	hemoglobin	NN
cord-022561-rv5j1201	417	11	may	may	MD
cord-022561-rv5j1201	417	12	cause	cause	VB
cord-022561-rv5j1201	417	13	an	an	DT
cord-022561-rv5j1201	417	14	artifactual	artifactual	JJ
cord-022561-rv5j1201	417	15	increase	increase	NN
cord-022561-rv5j1201	417	16	in	in	IN
cord-022561-rv5j1201	417	17	the	the	DT
cord-022561-rv5j1201	417	18	calculated	calculate	VBN
cord-022561-rv5j1201	417	19	MCH	MCH	NNP
cord-022561-rv5j1201	417	20	and	and	CC
cord-022561-rv5j1201	417	21	MCHC	MCHC	NNP
cord-022561-rv5j1201	417	22	.	.	.
cord-022561-rv5j1201	418	1	It	-PRON-	PRP
cord-022561-rv5j1201	418	2	is	be	VBZ
cord-022561-rv5j1201	418	3	important	important	JJ
cord-022561-rv5j1201	418	4	to	to	TO
cord-022561-rv5j1201	418	5	remember	remember	VB
cord-022561-rv5j1201	418	6	that	that	IN
cord-022561-rv5j1201	418	7	similar	similar	JJ
cord-022561-rv5j1201	418	8	artifactual	artifactual	JJ
cord-022561-rv5j1201	418	9	increases	increase	NNS
cord-022561-rv5j1201	418	10	may	may	MD
cord-022561-rv5j1201	418	11	also	also	RB
cord-022561-rv5j1201	418	12	occur	occur	VB
cord-022561-rv5j1201	418	13	with	with	IN
cord-022561-rv5j1201	418	14	lipemia	lipemia	NNP
cord-022561-rv5j1201	418	15	.	.	.
cord-022561-rv5j1201	419	1	Once	once	IN
cord-022561-rv5j1201	419	2	hemolytic	hemolytic	JJ
cord-022561-rv5j1201	419	3	anemia	anemia	NN
cord-022561-rv5j1201	419	4	has	have	VBZ
cord-022561-rv5j1201	419	5	been	be	VBN
cord-022561-rv5j1201	419	6	identified	identify	VBN
cord-022561-rv5j1201	419	7	,	,	,
cord-022561-rv5j1201	419	8	the	the	DT
cord-022561-rv5j1201	419	9	specific	specific	JJ
cord-022561-rv5j1201	419	10	cause	cause	NN
cord-022561-rv5j1201	419	11	for	for	IN
cord-022561-rv5j1201	419	12	hemolysis	hemolysis	NN
cord-022561-rv5j1201	419	13	should	should	MD
cord-022561-rv5j1201	419	14	be	be	VB
cord-022561-rv5j1201	419	15	investigated	investigate	VBN
cord-022561-rv5j1201	419	16	based	base	VBN
cord-022561-rv5j1201	419	17	on	on	IN
cord-022561-rv5j1201	419	18	signalment	signalment	JJ
cord-022561-rv5j1201	419	19	,	,	,
cord-022561-rv5j1201	419	20	clinical	clinical	JJ
cord-022561-rv5j1201	419	21	history	history	NN
cord-022561-rv5j1201	419	22	,	,	,
cord-022561-rv5j1201	419	23	and	and	CC
cord-022561-rv5j1201	419	24	microscopic	microscopic	JJ
cord-022561-rv5j1201	419	25	blood	blood	NN
cord-022561-rv5j1201	419	26	smear	smear	NN
cord-022561-rv5j1201	419	27	evaluation	evaluation	NN
cord-022561-rv5j1201	419	28	.	.	.
cord-022561-rv5j1201	420	1	The	the	DT
cord-022561-rv5j1201	420	2	most	most	RBS
cord-022561-rv5j1201	420	3	common	common	JJ
cord-022561-rv5j1201	420	4	causes	cause	NNS
cord-022561-rv5j1201	420	5	of	of	IN
cord-022561-rv5j1201	420	6	hemolytic	hemolytic	JJ
cord-022561-rv5j1201	420	7	anemia	anemia	NN
cord-022561-rv5j1201	420	8	in	in	IN
cord-022561-rv5j1201	420	9	domestic	domestic	JJ
cord-022561-rv5j1201	420	10	animals	animal	NNS
cord-022561-rv5j1201	420	11	are	be	VBP
cord-022561-rv5j1201	420	12	immunemediated	immunemediate	VBN
cord-022561-rv5j1201	420	13	,	,	,
cord-022561-rv5j1201	420	14	infectious	infectious	JJ
cord-022561-rv5j1201	420	15	,	,	,
cord-022561-rv5j1201	420	16	oxidative	oxidative	JJ
cord-022561-rv5j1201	420	17	,	,	,
cord-022561-rv5j1201	420	18	and	and	CC
cord-022561-rv5j1201	420	19	mechanical	mechanical	JJ
cord-022561-rv5j1201	420	20	fragmentation	fragmentation	NN
cord-022561-rv5j1201	420	21	(	(	-LRB-
cord-022561-rv5j1201	420	22	i.e.	i.e.	FW
cord-022561-rv5j1201	420	23	,	,	,
cord-022561-rv5j1201	420	24	microangiopathic	microangiopathic	JJ
cord-022561-rv5j1201	420	25	)	)	-RRB-
cord-022561-rv5j1201	420	26	disorders	disorder	NNS
cord-022561-rv5j1201	420	27	(	(	-LRB-
cord-022561-rv5j1201	420	28	Table	Table	NNP
cord-022561-rv5j1201	420	29	13	13	CD
cord-022561-rv5j1201	420	30	-	-	SYM
cord-022561-rv5j1201	420	31	3	3	CD
cord-022561-rv5j1201	420	32	)	)	-RRB-
cord-022561-rv5j1201	420	33	.	.	.
cord-022561-rv5j1201	421	1	Spherocytosis	spherocytosis	NN
cord-022561-rv5j1201	421	2	and	and	CC
cord-022561-rv5j1201	421	3	autoagglutination	autoagglutination	NN
cord-022561-rv5j1201	421	4	are	be	VBP
cord-022561-rv5j1201	421	5	hallmarks	hallmark	NNS
cord-022561-rv5j1201	421	6	of	of	IN
cord-022561-rv5j1201	421	7	immunemediated	immunemediated	JJ
cord-022561-rv5j1201	421	8	hemolytic	hemolytic	JJ
cord-022561-rv5j1201	421	9	anemia	anemia	NN
cord-022561-rv5j1201	421	10	,	,	,
cord-022561-rv5j1201	421	11	either	either	CC
cord-022561-rv5j1201	421	12	primary	primary	JJ
cord-022561-rv5j1201	421	13	(	(	-LRB-
cord-022561-rv5j1201	421	14	also	also	RB
cord-022561-rv5j1201	421	15	known	know	VBN
cord-022561-rv5j1201	421	16	as	as	IN
cord-022561-rv5j1201	421	17	idiopathic	idiopathic	JJ
cord-022561-rv5j1201	421	18	)	)	-RRB-
cord-022561-rv5j1201	421	19	or	or	CC
cord-022561-rv5j1201	421	20	secondary	secondary	JJ
cord-022561-rv5j1201	421	21	to	to	IN
cord-022561-rv5j1201	421	22	infectious	infectious	JJ
cord-022561-rv5j1201	421	23	disease	disease	NN
cord-022561-rv5j1201	421	24	,	,	,
cord-022561-rv5j1201	421	25	drugs	drug	NNS
cord-022561-rv5j1201	421	26	/	/	SYM
cord-022561-rv5j1201	421	27	toxins	toxin	NNS
cord-022561-rv5j1201	421	28	,	,	,
cord-022561-rv5j1201	421	29	or	or	CC
cord-022561-rv5j1201	421	30	neoplasms	neoplasm	NNS
cord-022561-rv5j1201	421	31	.	.	.
cord-022561-rv5j1201	422	1	Several	several	JJ
cord-022561-rv5j1201	422	2	initiating	initiate	VBG
cord-022561-rv5j1201	422	3	processes	process	NNS
cord-022561-rv5j1201	422	4	can	can	MD
cord-022561-rv5j1201	422	5	cause	cause	VB
cord-022561-rv5j1201	422	6	intravascular	intravascular	JJ
cord-022561-rv5j1201	422	7	hemolysis	hemolysis	NN
cord-022561-rv5j1201	422	8	;	;	:
cord-022561-rv5j1201	422	9	formation	formation	NN
cord-022561-rv5j1201	422	10	of	of	IN
cord-022561-rv5j1201	422	11	the	the	DT
cord-022561-rv5j1201	422	12	complement	complement	JJ
cord-022561-rv5j1201	422	13	membrane	membrane	NN
cord-022561-rv5j1201	422	14	attack	attack	NN
cord-022561-rv5j1201	422	15	complex	complex	NN
cord-022561-rv5j1201	422	16	is	be	VBZ
cord-022561-rv5j1201	422	17	pictured	picture	VBN
cord-022561-rv5j1201	422	18	.	.	.
cord-022561-rv5j1201	423	1	With	with	IN
cord-022561-rv5j1201	423	2	intravascular	intravascular	JJ
cord-022561-rv5j1201	423	3	hemolysis	hemolysis	NN
cord-022561-rv5j1201	423	4	,	,	,
cord-022561-rv5j1201	423	5	free	free	JJ
cord-022561-rv5j1201	423	6	hemoglobin	hemoglobin	NN
cord-022561-rv5j1201	423	7	is	be	VBZ
cord-022561-rv5j1201	423	8	release	release	NN
cord-022561-rv5j1201	423	9	directly	directly	RB
cord-022561-rv5j1201	423	10	into	into	IN
cord-022561-rv5j1201	423	11	the	the	DT
cord-022561-rv5j1201	423	12	plasma	plasma	NN
cord-022561-rv5j1201	423	13	,	,	,
cord-022561-rv5j1201	423	14	where	where	WRB
cord-022561-rv5j1201	423	15	it	-PRON-	PRP
cord-022561-rv5j1201	423	16	is	be	VBZ
cord-022561-rv5j1201	423	17	scavenged	scavenge	VBN
cord-022561-rv5j1201	423	18	by	by	IN
cord-022561-rv5j1201	423	19	haptoglobin	haptoglobin	NN
cord-022561-rv5j1201	423	20	and	and	CC
cord-022561-rv5j1201	423	21	hemopexin	hemopexin	NN
cord-022561-rv5j1201	423	22	.	.	.
cord-022561-rv5j1201	424	1	When	when	WRB
cord-022561-rv5j1201	424	2	haptoglobin	haptoglobin	NN
cord-022561-rv5j1201	424	3	and	and	CC
cord-022561-rv5j1201	424	4	hemopexin	hemopexin	NNP
cord-022561-rv5j1201	424	5	are	be	VBP
cord-022561-rv5j1201	424	6	saturated	saturate	VBN
cord-022561-rv5j1201	424	7	,	,	,
cord-022561-rv5j1201	424	8	the	the	DT
cord-022561-rv5j1201	424	9	cell	cell	NN
cord-022561-rv5j1201	424	10	-	-	HYPH
cord-022561-rv5j1201	424	11	free	free	JJ
cord-022561-rv5j1201	424	12	hemoglobin	hemoglobin	NN
cord-022561-rv5j1201	424	13	causes	cause	VBZ
cord-022561-rv5j1201	424	14	red	red	JJ
cord-022561-rv5j1201	424	15	discoloration	discoloration	NN
cord-022561-rv5j1201	424	16	of	of	IN
cord-022561-rv5j1201	424	17	the	the	DT
cord-022561-rv5j1201	424	18	plasma	plasma	NN
cord-022561-rv5j1201	424	19	(	(	-LRB-
cord-022561-rv5j1201	424	20	hemolysis	hemolysis	NN
cord-022561-rv5j1201	424	21	)	)	-RRB-
cord-022561-rv5j1201	424	22	and	and	CC
cord-022561-rv5j1201	424	23	is	be	VBZ
cord-022561-rv5j1201	424	24	excreted	excrete	VBN
cord-022561-rv5j1201	424	25	in	in	IN
cord-022561-rv5j1201	424	26	the	the	DT
cord-022561-rv5j1201	424	27	urine	urine	NN
cord-022561-rv5j1201	424	28	(	(	-LRB-
cord-022561-rv5j1201	424	29	hemoglobinuria	hemoglobinuria	NNP
cord-022561-rv5j1201	424	30	;	;	:
cord-022561-rv5j1201	424	31	dark	dark	JJ
cord-022561-rv5j1201	424	32	red	red	JJ
cord-022561-rv5j1201	424	33	urine	urine	NN
cord-022561-rv5j1201	424	34	)	)	-RRB-
cord-022561-rv5j1201	424	35	.	.	.
cord-022561-rv5j1201	425	1	The	the	DT
cord-022561-rv5j1201	425	2	liver	liver	NN
cord-022561-rv5j1201	425	3	clears	clear	VBZ
cord-022561-rv5j1201	425	4	haptoglobinhemoglobin	haptoglobinhemoglobin	NNP
cord-022561-rv5j1201	425	5	and	and	CC
cord-022561-rv5j1201	425	6	hemopexin	hemopexin	JJ
cord-022561-rv5j1201	425	7	-	-	HYPH
cord-022561-rv5j1201	425	8	methemoglobin	methemoglobin	JJ
cord-022561-rv5j1201	425	9	complexes	complex	NNS
cord-022561-rv5j1201	425	10	from	from	IN
cord-022561-rv5j1201	425	11	plasma	plasma	NN
cord-022561-rv5j1201	425	12	and	and	CC
cord-022561-rv5j1201	425	13	converts	convert	VBZ
cord-022561-rv5j1201	425	14	hemoglobin	hemoglobin	NN
cord-022561-rv5j1201	425	15	to	to	IN
cord-022561-rv5j1201	425	16	unconjugated	unconjugated	JJ
cord-022561-rv5j1201	425	17	bilirubin	bilirubin	NN
cord-022561-rv5j1201	425	18	and	and	CC
cord-022561-rv5j1201	425	19	then	then	RB
cord-022561-rv5j1201	425	20	conjugated	conjugate	VBD
cord-022561-rv5j1201	425	21	bilirubin	bilirubin	NN
cord-022561-rv5j1201	425	22	.	.	.
cord-022561-rv5j1201	426	1	Conjugated	conjugated	JJ
cord-022561-rv5j1201	426	2	bilirubin	bilirubin	NN
cord-022561-rv5j1201	426	3	is	be	VBZ
cord-022561-rv5j1201	426	4	normally	normally	RB
cord-022561-rv5j1201	426	5	excreted	excrete	VBN
cord-022561-rv5j1201	426	6	in	in	IN
cord-022561-rv5j1201	426	7	the	the	DT
cord-022561-rv5j1201	426	8	bile	bile	NN
cord-022561-rv5j1201	426	9	and	and	CC
cord-022561-rv5j1201	426	10	then	then	RB
cord-022561-rv5j1201	426	11	converted	convert	VBD
cord-022561-rv5j1201	426	12	to	to	IN
cord-022561-rv5j1201	426	13	urobilinogen	urobilinogen	NNP
cord-022561-rv5j1201	426	14	(	(	-LRB-
cord-022561-rv5j1201	426	15	yellow	yellow	NNP
cord-022561-rv5j1201	426	16	)	)	-RRB-
cord-022561-rv5j1201	426	17	and	and	CC
cord-022561-rv5j1201	426	18	subsequently	subsequently	RB
cord-022561-rv5j1201	426	19	stercobilinogen	stercobilinogen	NNP
cord-022561-rv5j1201	426	20	(	(	-LRB-
cord-022561-rv5j1201	426	21	dark	dark	NNP
cord-022561-rv5j1201	426	22	brown	brown	NNP
cord-022561-rv5j1201	426	23	)	)	-RRB-
cord-022561-rv5j1201	426	24	.	.	.
cord-022561-rv5j1201	427	1	However	however	RB
cord-022561-rv5j1201	427	2	,	,	,
cord-022561-rv5j1201	427	3	excessive	excessive	JJ
cord-022561-rv5j1201	427	4	bilirubin	bilirubin	NN
cord-022561-rv5j1201	427	5	will	will	MD
cord-022561-rv5j1201	427	6	spill	spill	VB
cord-022561-rv5j1201	427	7	over	over	RP
cord-022561-rv5j1201	427	8	into	into	IN
cord-022561-rv5j1201	427	9	the	the	DT
cord-022561-rv5j1201	427	10	plasma	plasma	NN
cord-022561-rv5j1201	427	11	,	,	,
cord-022561-rv5j1201	427	12	resulting	result	VBG
cord-022561-rv5j1201	427	13	in	in	IN
cord-022561-rv5j1201	427	14	hyperbilirubinemia	hyperbilirubinemia	NN
cord-022561-rv5j1201	427	15	,	,	,
cord-022561-rv5j1201	427	16	icteric	icteric	JJ
cord-022561-rv5j1201	427	17	plasma	plasma	NN
cord-022561-rv5j1201	427	18	(	(	-LRB-
cord-022561-rv5j1201	427	19	if	if	IN
cord-022561-rv5j1201	427	20	severe	severe	JJ
cord-022561-rv5j1201	427	21	enough	enough	RB
cord-022561-rv5j1201	427	22	)	)	-RRB-
cord-022561-rv5j1201	427	23	,	,	,
cord-022561-rv5j1201	427	24	and	and	CC
cord-022561-rv5j1201	427	25	urinary	urinary	JJ
cord-022561-rv5j1201	427	26	excretion	excretion	NN
cord-022561-rv5j1201	427	27	of	of	IN
cord-022561-rv5j1201	427	28	bilirubin	bilirubin	NN
cord-022561-rv5j1201	427	29	(	(	-LRB-
cord-022561-rv5j1201	427	30	bilirubinuria	bilirubinuria	NNP
cord-022561-rv5j1201	427	31	;	;	,
cord-022561-rv5j1201	427	32	icteric	icteric	JJ
cord-022561-rv5j1201	427	33	urine	urine	NN
cord-022561-rv5j1201	427	34	)	)	-RRB-
cord-022561-rv5j1201	427	35	.	.	.
cord-022561-rv5j1201	428	1	Extravascular	extravascular	JJ
cord-022561-rv5j1201	428	2	hemolysis	hemolysis	NN
cord-022561-rv5j1201	429	1	:	:	:
cord-022561-rv5j1201	429	2	During	during	IN
cord-022561-rv5j1201	429	3	extravascular	extravascular	JJ
cord-022561-rv5j1201	429	4	hemolysis	hemolysis	NN
cord-022561-rv5j1201	429	5	,	,	,
cord-022561-rv5j1201	429	6	erythrocytes	erythrocyte	NNS
cord-022561-rv5j1201	429	7	are	be	VBP
cord-022561-rv5j1201	429	8	phagocytized	phagocytize	VBN
cord-022561-rv5j1201	429	9	by	by	IN
cord-022561-rv5j1201	429	10	macrophages	macrophage	NNS
cord-022561-rv5j1201	429	11	,	,	,
cord-022561-rv5j1201	429	12	which	which	WDT
cord-022561-rv5j1201	429	13	digest	digest	VBP
cord-022561-rv5j1201	429	14	erythrocytes	erythrocyte	NNS
cord-022561-rv5j1201	429	15	,	,	,
cord-022561-rv5j1201	429	16	and	and	CC
cord-022561-rv5j1201	429	17	convert	convert	VB
cord-022561-rv5j1201	429	18	hemoglobin	hemoglobin	NN
cord-022561-rv5j1201	429	19	to	to	IN
cord-022561-rv5j1201	429	20	unconjugated	unconjugated	JJ
cord-022561-rv5j1201	429	21	bilirubin	bilirubin	NN
cord-022561-rv5j1201	429	22	.	.	.
cord-022561-rv5j1201	430	1	Excessive	excessive	JJ
cord-022561-rv5j1201	430	2	bilirubin	bilirubin	NN
cord-022561-rv5j1201	430	3	in	in	IN
cord-022561-rv5j1201	430	4	plasma	plasma	NN
cord-022561-rv5j1201	430	5	causes	cause	VBZ
cord-022561-rv5j1201	430	6	hyperbilirubinemia	hyperbilirubinemia	NN
cord-022561-rv5j1201	430	7	with	with	IN
cord-022561-rv5j1201	430	8	or	or	CC
cord-022561-rv5j1201	430	9	without	without	IN
cord-022561-rv5j1201	430	10	icteric	icteric	JJ
cord-022561-rv5j1201	430	11	plasma	plasma	NN
cord-022561-rv5j1201	430	12	.	.	.
cord-022561-rv5j1201	431	1	Unconjugated	unconjugated	JJ
cord-022561-rv5j1201	431	2	bilirubin	bilirubin	NN
cord-022561-rv5j1201	431	3	is	be	VBZ
cord-022561-rv5j1201	431	4	processed	process	VBN
cord-022561-rv5j1201	431	5	and	and	CC
cord-022561-rv5j1201	431	6	excreted	excrete	VBN
cord-022561-rv5j1201	431	7	by	by	IN
cord-022561-rv5j1201	431	8	the	the	DT
cord-022561-rv5j1201	431	9	liver	liver	NN
cord-022561-rv5j1201	431	10	(	(	-LRB-
cord-022561-rv5j1201	431	11	as	as	RB
cord-022561-rv5j1201	431	12	previously	previously	RB
cord-022561-rv5j1201	431	13	described	describe	VBN
cord-022561-rv5j1201	431	14	)	)	-RRB-
cord-022561-rv5j1201	431	15	and	and	CC
cord-022561-rv5j1201	431	16	in	in	IN
cord-022561-rv5j1201	431	17	dogs	dog	NNS
cord-022561-rv5j1201	431	18	,	,	,
cord-022561-rv5j1201	431	19	the	the	DT
cord-022561-rv5j1201	431	20	kidney	kidney	NN
cord-022561-rv5j1201	431	21	.	.	.
cord-022561-rv5j1201	431	22	 	 	_SP
cord-022561-rv5j1201	432	1	Kidney	kidney	NN
cord-022561-rv5j1201	432	2	U	u	NN
cord-022561-rv5j1201	432	3	-	-	HYPH
cord-022561-rv5j1201	432	4	bilirubin	bilirubin	JJ
cord-022561-rv5j1201	432	5	cattle	cattle	NNS
cord-022561-rv5j1201	432	6	,	,	,
cord-022561-rv5j1201	432	7	and	and	CC
cord-022561-rv5j1201	432	8	cats	cat	NNS
cord-022561-rv5j1201	432	9	)	)	-RRB-
cord-022561-rv5j1201	432	10	,	,	,
cord-022561-rv5j1201	432	11	whose	whose	WP$
cord-022561-rv5j1201	432	12	erythrocytes	erythrocyte	NNS
cord-022561-rv5j1201	432	13	differ	differ	VBP
cord-022561-rv5j1201	432	14	from	from	IN
cord-022561-rv5j1201	432	15	those	those	DT
cord-022561-rv5j1201	432	16	of	of	IN
cord-022561-rv5j1201	432	17	the	the	DT
cord-022561-rv5j1201	432	18	dog	dog	NN
cord-022561-rv5j1201	432	19	in	in	IN
cord-022561-rv5j1201	432	20	that	that	IN
cord-022561-rv5j1201	432	21	they	-PRON-	PRP
cord-022561-rv5j1201	432	22	are	be	VBP
cord-022561-rv5j1201	432	23	smaller	small	JJR
cord-022561-rv5j1201	432	24	and	and	CC
cord-022561-rv5j1201	432	25	have	have	VBP
cord-022561-rv5j1201	432	26	less	less	RBR
cord-022561-rv5j1201	432	27	pronounced	pronounce	VBN
cord-022561-rv5j1201	432	28	biconcavity	biconcavity	NN
cord-022561-rv5j1201	432	29	and	and	CC
cord-022561-rv5j1201	432	30	therefore	therefore	RB
cord-022561-rv5j1201	432	31	less	less	RBR
cord-022561-rv5j1201	432	32	pronounced	pronounce	VBN
cord-022561-rv5j1201	432	33	central	central	JJ
cord-022561-rv5j1201	432	34	pallor	pallor	NN
cord-022561-rv5j1201	432	35	.	.	.
cord-022561-rv5j1201	433	1	Autoagglutination	autoagglutination	NN
cord-022561-rv5j1201	433	2	occurs	occur	VBZ
cord-022561-rv5j1201	433	3	because	because	IN
cord-022561-rv5j1201	433	4	of	of	IN
cord-022561-rv5j1201	433	5	cross	cross	NN
cord-022561-rv5j1201	433	6	-	-	NN
cord-022561-rv5j1201	433	7	linking	linking	NN
cord-022561-rv5j1201	433	8	of	of	IN
cord-022561-rv5j1201	433	9	antibodies	antibody	NNS
cord-022561-rv5j1201	433	10	bound	bind	VBN
cord-022561-rv5j1201	433	11	to	to	IN
cord-022561-rv5j1201	433	12	erythrocytes	erythrocyte	NNS
cord-022561-rv5j1201	433	13	(	(	-LRB-
cord-022561-rv5j1201	433	14	see	see	VB
cord-022561-rv5j1201	433	15	.	.	.
cord-022561-rv5j1201	434	1	Autoagglutination	autoagglutination	NN
cord-022561-rv5j1201	434	2	is	be	VBZ
cord-022561-rv5j1201	434	3	evident	evident	JJ
cord-022561-rv5j1201	434	4	macroscopically	macroscopically	RB
cord-022561-rv5j1201	434	5	as	as	IN
cord-022561-rv5j1201	434	6	blood	blood	NN
cord-022561-rv5j1201	434	7	with	with	IN
cord-022561-rv5j1201	434	8	a	a	DT
cord-022561-rv5j1201	434	9	grainy	grainy	JJ
cord-022561-rv5j1201	434	10	consistency	consistency	NN
cord-022561-rv5j1201	434	11	(	(	-LRB-
cord-022561-rv5j1201	434	12	see	see	VB
cord-022561-rv5j1201	434	13	Fig	Fig	NNP
cord-022561-rv5j1201	434	14	.	.	.
cord-022561-rv5j1201	435	1	13	13	CD
cord-022561-rv5j1201	435	2	-	-	SYM
cord-022561-rv5j1201	435	3	13	13	CD
cord-022561-rv5j1201	435	4	,	,	,
cord-022561-rv5j1201	435	5	B	B	NNP
cord-022561-rv5j1201	435	6	)	)	-RRB-
cord-022561-rv5j1201	435	7	,	,	,
cord-022561-rv5j1201	435	8	and	and	CC
cord-022561-rv5j1201	435	9	microscopically	microscopically	RB
cord-022561-rv5j1201	435	10	as	as	IN
cord-022561-rv5j1201	435	11	clusters	cluster	NNS
cord-022561-rv5j1201	435	12	of	of	IN
cord-022561-rv5j1201	435	13	erythrocytes	erythrocyte	NNS
cord-022561-rv5j1201	435	14	(	(	-LRB-
cord-022561-rv5j1201	435	15	see	see	VB
cord-022561-rv5j1201	435	16	Fig	Fig	NNP
cord-022561-rv5j1201	435	17	.	.	.
cord-022561-rv5j1201	436	1	13	13	CD
cord-022561-rv5j1201	436	2	-13	-13	NNS
cord-022561-rv5j1201	436	3	,	,	,
cord-022561-rv5j1201	436	4	C	C	NNP
cord-022561-rv5j1201	436	5	)	)	-RRB-
cord-022561-rv5j1201	436	6	.	.	.
cord-022561-rv5j1201	437	1	Autoagglutination	Autoagglutination	NNP
cord-022561-rv5j1201	437	2	may	may	MD
cord-022561-rv5j1201	437	3	also	also	RB
cord-022561-rv5j1201	437	4	result	result	VB
cord-022561-rv5j1201	437	5	in	in	IN
cord-022561-rv5j1201	437	6	a	a	DT
cord-022561-rv5j1201	437	7	falsely	falsely	RB
cord-022561-rv5j1201	437	8	increased	increase	VBN
cord-022561-rv5j1201	437	9	MCV	MCV	NNP
cord-022561-rv5j1201	437	10	and	and	CC
cord-022561-rv5j1201	437	11	decreased	decrease	VBD
cord-022561-rv5j1201	437	12	red	red	JJ
cord-022561-rv5j1201	437	13	blood	blood	NN
cord-022561-rv5j1201	437	14	cell	cell	NN
cord-022561-rv5j1201	437	15	concentration	concentration	NN
cord-022561-rv5j1201	437	16	when	when	WRB
cord-022561-rv5j1201	437	17	clustered	cluster	VBN
cord-022561-rv5j1201	437	18	cells	cell	NNS
cord-022561-rv5j1201	437	19	are	be	VBP
cord-022561-rv5j1201	437	20	mistakenly	mistakenly	RB
cord-022561-rv5j1201	437	21	counted	count	VBN
cord-022561-rv5j1201	437	22	as	as	IN
cord-022561-rv5j1201	437	23	single	single	JJ
cord-022561-rv5j1201	437	24	cells	cell	NNS
cord-022561-rv5j1201	437	25	by	by	IN
cord-022561-rv5j1201	437	26	automated	automate	VBN
cord-022561-rv5j1201	437	27	hematology	hematology	NN
cord-022561-rv5j1201	437	28	analyzers	analyzer	NNS
cord-022561-rv5j1201	437	29	.	.	.
cord-022561-rv5j1201	438	1	When	when	WRB
cord-022561-rv5j1201	438	2	autoagglutination	autoagglutination	NN
cord-022561-rv5j1201	438	3	is	be	VBZ
cord-022561-rv5j1201	438	4	present	present	JJ
cord-022561-rv5j1201	438	5	,	,	,
cord-022561-rv5j1201	438	6	the	the	DT
cord-022561-rv5j1201	438	7	packed	pack	VBN
cord-022561-rv5j1201	438	8	-	-	HYPH
cord-022561-rv5j1201	438	9	cell	cell	NN
cord-022561-rv5j1201	438	10	volume	volume	NN
cord-022561-rv5j1201	438	11	is	be	VBZ
cord-022561-rv5j1201	438	12	the	the	DT
cord-022561-rv5j1201	438	13	most	most	RBS
cord-022561-rv5j1201	438	14	reliable	reliable	JJ
cord-022561-rv5j1201	438	15	measurement	measurement	NN
cord-022561-rv5j1201	438	16	of	of	IN
cord-022561-rv5j1201	438	17	red	red	JJ
cord-022561-rv5j1201	438	18	blood	blood	NN
cord-022561-rv5j1201	438	19	cell	cell	NN
cord-022561-rv5j1201	438	20	mass	mass	NN
cord-022561-rv5j1201	438	21	.	.	.
cord-022561-rv5j1201	439	1	Ghost	ghost	NN
cord-022561-rv5j1201	439	2	cells	cell	NNS
cord-022561-rv5j1201	439	3	are	be	VBP
cord-022561-rv5j1201	439	4	ruptured	rupture	VBN
cord-022561-rv5j1201	439	5	red	red	JJ
cord-022561-rv5j1201	439	6	blood	blood	NN
cord-022561-rv5j1201	439	7	cell	cell	NN
cord-022561-rv5j1201	439	8	membranes	membrane	NNS
cord-022561-rv5j1201	439	9	devoid	devoid	JJ
cord-022561-rv5j1201	439	10	of	of	IN
cord-022561-rv5j1201	439	11	cytoplasmic	cytoplasmic	JJ
cord-022561-rv5j1201	439	12	contents	content	NNS
cord-022561-rv5j1201	439	13	(	(	-LRB-
cord-022561-rv5j1201	439	14	see	see	VB
cord-022561-rv5j1201	439	15	A	a	DT
cord-022561-rv5j1201	439	16	)	)	-RRB-
cord-022561-rv5j1201	439	17	.	.	.
cord-022561-rv5j1201	440	1	They	-PRON-	PRP
cord-022561-rv5j1201	440	2	indicate	indicate	VBP
cord-022561-rv5j1201	440	3	intravascular	intravascular	JJ
cord-022561-rv5j1201	440	4	hemolysis	hemolysis	NN
cord-022561-rv5j1201	440	5	and	and	CC
cord-022561-rv5j1201	440	6	may	may	MD
cord-022561-rv5j1201	440	7	be	be	VB
cord-022561-rv5j1201	440	8	seen	see	VBN
cord-022561-rv5j1201	440	9	with	with	IN
cord-022561-rv5j1201	440	10	a	a	DT
cord-022561-rv5j1201	440	11	variety	variety	NN
cord-022561-rv5j1201	440	12	of	of	IN
cord-022561-rv5j1201	440	13	hemolytic	hemolytic	JJ
cord-022561-rv5j1201	440	14	disorders	disorder	NNS
cord-022561-rv5j1201	440	15	,	,	,
cord-022561-rv5j1201	440	16	including	include	VBG
cord-022561-rv5j1201	440	17	those	those	DT
cord-022561-rv5j1201	440	18	with	with	IN
cord-022561-rv5j1201	440	19	immune	immune	NN
cord-022561-rv5j1201	440	20	-	-	HYPH
cord-022561-rv5j1201	440	21	mediated	mediate	VBN
cord-022561-rv5j1201	440	22	,	,	,
cord-022561-rv5j1201	440	23	infectious	infectious	JJ
cord-022561-rv5j1201	440	24	,	,	,
cord-022561-rv5j1201	440	25	oxidative	oxidative	JJ
cord-022561-rv5j1201	440	26	,	,	,
cord-022561-rv5j1201	440	27	or	or	CC
cord-022561-rv5j1201	440	28	fragmentation	fragmentation	NN
cord-022561-rv5j1201	440	29	causes	cause	NNS
cord-022561-rv5j1201	440	30	.	.	.
cord-022561-rv5j1201	441	1	In	in	IN
cord-022561-rv5j1201	441	2	the	the	DT
cord-022561-rv5j1201	441	3	case	case	NN
cord-022561-rv5j1201	441	4	of	of	IN
cord-022561-rv5j1201	441	5	immune	immune	NN
cord-022561-rv5j1201	441	6	-	-	HYPH
cord-022561-rv5j1201	441	7	mediated	mediate	VBN
cord-022561-rv5j1201	441	8	hemolytic	hemolytic	JJ
cord-022561-rv5j1201	441	9	anemia	anemia	NN
cord-022561-rv5j1201	441	10	,	,	,
cord-022561-rv5j1201	441	11	antibody	antibody	NN
cord-022561-rv5j1201	441	12	or	or	CC
cord-022561-rv5j1201	441	13	complement	complement	VB
cord-022561-rv5j1201	441	14	binds	bind	VBZ
cord-022561-rv5j1201	441	15	to	to	IN
cord-022561-rv5j1201	441	16	red	red	JJ
cord-022561-rv5j1201	441	17	blood	blood	NN
cord-022561-rv5j1201	441	18	cell	cell	NN
cord-022561-rv5j1201	441	19	membranes	membrane	NNS
cord-022561-rv5j1201	441	20	and	and	CC
cord-022561-rv5j1201	441	21	activates	activate	VBZ
cord-022561-rv5j1201	441	22	the	the	DT
cord-022561-rv5j1201	441	23	complement	complement	NN
cord-022561-rv5j1201	441	24	membrane	membrane	NN
cord-022561-rv5j1201	441	25	attack	attack	NN
cord-022561-rv5j1201	441	26	complex	complex	NN
cord-022561-rv5j1201	441	27	(	(	-LRB-
cord-022561-rv5j1201	441	28	see	see	VB
cord-022561-rv5j1201	441	29	Fig	Fig	NNP
cord-022561-rv5j1201	441	30	.	.	NNP
cord-022561-rv5j1201	441	31	13	13	CD
cord-022561-rv5j1201	441	32	-12	-12	CD
cord-022561-rv5j1201	441	33	)	)	-RRB-
cord-022561-rv5j1201	441	34	.	.	.
cord-022561-rv5j1201	442	1	This	this	DT
cord-022561-rv5j1201	442	2	causes	cause	VBZ
cord-022561-rv5j1201	442	3	pore	pore	NN
cord-022561-rv5j1201	442	4	formation	formation	NN
cord-022561-rv5j1201	442	5	in	in	IN
cord-022561-rv5j1201	442	6	the	the	DT
cord-022561-rv5j1201	442	7	red	red	JJ
cord-022561-rv5j1201	442	8	blood	blood	NN
cord-022561-rv5j1201	442	9	cell	cell	NN
cord-022561-rv5j1201	442	10	membrane	membrane	NN
cord-022561-rv5j1201	442	11	and	and	CC
cord-022561-rv5j1201	442	12	release	release	NN
cord-022561-rv5j1201	442	13	of	of	IN
cord-022561-rv5j1201	442	14	cytoplasmic	cytoplasmic	JJ
cord-022561-rv5j1201	442	15	contents	content	NNS
cord-022561-rv5j1201	442	16	into	into	IN
cord-022561-rv5j1201	442	17	the	the	DT
cord-022561-rv5j1201	442	18	plasma	plasma	NN
cord-022561-rv5j1201	442	19	.	.	.
cord-022561-rv5j1201	443	1	Ghost	ghost	NN
cord-022561-rv5j1201	443	2	cells	cell	NNS
cord-022561-rv5j1201	443	3	are	be	VBP
cord-022561-rv5j1201	443	4	eventually	eventually	RB
cord-022561-rv5j1201	443	5	cleared	clear	VBN
cord-022561-rv5j1201	443	6	from	from	IN
cord-022561-rv5j1201	443	7	circulation	circulation	NN
cord-022561-rv5j1201	443	8	by	by	IN
cord-022561-rv5j1201	443	9	phagocytic	phagocytic	JJ
cord-022561-rv5j1201	443	10	macrophages	macrophage	NNS
cord-022561-rv5j1201	443	11	,	,	,
cord-022561-rv5j1201	443	12	mainly	mainly	RB
cord-022561-rv5j1201	443	13	within	within	IN
cord-022561-rv5j1201	443	14	the	the	DT
cord-022561-rv5j1201	443	15	spleen	spleen	NN
cord-022561-rv5j1201	443	16	.	.	.
cord-022561-rv5j1201	444	1	Oxidative	oxidative	JJ
cord-022561-rv5j1201	444	2	damage	damage	NN
cord-022561-rv5j1201	444	3	to	to	IN
cord-022561-rv5j1201	444	4	erythrocytes	erythrocyte	NNS
cord-022561-rv5j1201	444	5	occurs	occur	VBZ
cord-022561-rv5j1201	444	6	when	when	WRB
cord-022561-rv5j1201	444	7	normal	normal	JJ
cord-022561-rv5j1201	444	8	antioxidative	antioxidative	JJ
cord-022561-rv5j1201	444	9	pathways	pathway	NNS
cord-022561-rv5j1201	444	10	that	that	WDT
cord-022561-rv5j1201	444	11	generate	generate	VBP
cord-022561-rv5j1201	444	12	reducing	reduce	VBG
cord-022561-rv5j1201	444	13	agents	agent	NNS
cord-022561-rv5j1201	444	14	(	(	-LRB-
cord-022561-rv5j1201	444	15	such	such	JJ
cord-022561-rv5j1201	444	16	as	as	IN
cord-022561-rv5j1201	444	17	reduced	reduce	VBN
cord-022561-rv5j1201	444	18	nicotinamide	nicotinamide	NN
cord-022561-rv5j1201	444	19	adenine	adenine	NN
cord-022561-rv5j1201	444	20	dinucleotide	dinucleotide	NN
cord-022561-rv5j1201	444	21	[	[	-LRB-
cord-022561-rv5j1201	444	22	NADH	NADH	NNP
cord-022561-rv5j1201	444	23	]	]	-RRB-
cord-022561-rv5j1201	444	24	,	,	,
cord-022561-rv5j1201	444	25	reduced	reduce	VBN
cord-022561-rv5j1201	444	26	nicotinamide	nicotinamide	NN
cord-022561-rv5j1201	444	27	adenine	adenine	NN
cord-022561-rv5j1201	444	28	dinucleotide	dinucleotide	NN
cord-022561-rv5j1201	444	29	phosphate	phosphate	NN
cord-022561-rv5j1201	444	30	[	[	-LRB-
cord-022561-rv5j1201	444	31	NADPH	NADPH	NNP
cord-022561-rv5j1201	444	32	]	]	-RRB-
cord-022561-rv5j1201	444	33	,	,	,
cord-022561-rv5j1201	444	34	and	and	CC
cord-022561-rv5j1201	444	35	reduced	reduce	VBN
cord-022561-rv5j1201	444	36	glutathione	glutathione	NN
cord-022561-rv5j1201	444	37	[	[	-LRB-
cord-022561-rv5j1201	444	38	GSH	GSH	NNP
cord-022561-rv5j1201	444	39	]	]	-RRB-
cord-022561-rv5j1201	444	40	)	)	-RRB-
cord-022561-rv5j1201	444	41	are	be	VBP
cord-022561-rv5j1201	444	42	compromised	compromise	VBN
cord-022561-rv5j1201	444	43	or	or	CC
cord-022561-rv5j1201	444	44	overwhelmed	overwhelmed	JJ
cord-022561-rv5j1201	444	45	,	,	,
cord-022561-rv5j1201	444	46	resulting	result	VBG
cord-022561-rv5j1201	444	47	in	in	IN
cord-022561-rv5j1201	444	48	hemolytic	hemolytic	JJ
cord-022561-rv5j1201	444	49	anemia	anemia	NN
cord-022561-rv5j1201	444	50	,	,	,
cord-022561-rv5j1201	444	51	abnormal	abnormal	JJ
cord-022561-rv5j1201	444	52	hemoglobin	hemoglobin	NN
cord-022561-rv5j1201	444	53	function	function	NN
cord-022561-rv5j1201	444	54	,	,	,
cord-022561-rv5j1201	444	55	or	or	CC
cord-022561-rv5j1201	444	56	both	both	DT
cord-022561-rv5j1201	444	57	.	.	.
cord-022561-rv5j1201	445	1	Hemolysis	Hemolysis	NNP
cord-022561-rv5j1201	445	2	caused	cause	VBN
cord-022561-rv5j1201	445	3	by	by	IN
cord-022561-rv5j1201	445	4	oxidative	oxidative	JJ
cord-022561-rv5j1201	445	5	damage	damage	NN
cord-022561-rv5j1201	445	6	may	may	MD
cord-022561-rv5j1201	445	7	be	be	VB
cord-022561-rv5j1201	445	8	extravascular	extravascular	JJ
cord-022561-rv5j1201	445	9	or	or	CC
cord-022561-rv5j1201	445	10	intravascular	intravascular	JJ
cord-022561-rv5j1201	445	11	,	,	,
cord-022561-rv5j1201	445	12	or	or	CC
cord-022561-rv5j1201	445	13	a	a	DT
cord-022561-rv5j1201	445	14	combination	combination	NN
cord-022561-rv5j1201	445	15	.	.	.
cord-022561-rv5j1201	446	1	Evidence	evidence	NN
cord-022561-rv5j1201	446	2	of	of	IN
cord-022561-rv5j1201	446	3	oxidative	oxidative	JJ
cord-022561-rv5j1201	446	4	damage	damage	NN
cord-022561-rv5j1201	446	5	to	to	IN
cord-022561-rv5j1201	446	6	erythrocytes	erythrocyte	NNS
cord-022561-rv5j1201	446	7	may	may	MD
cord-022561-rv5j1201	446	8	be	be	VB
cord-022561-rv5j1201	446	9	apparent	apparent	JJ
cord-022561-rv5j1201	446	10	on	on	IN
cord-022561-rv5j1201	446	11	blood	blood	NN
cord-022561-rv5j1201	446	12	smear	smear	NN
cord-022561-rv5j1201	446	13	examination	examination	NN
cord-022561-rv5j1201	446	14	as	as	IN
cord-022561-rv5j1201	446	15	Heinz	Heinz	NNP
cord-022561-rv5j1201	446	16	bodies	body	NNS
cord-022561-rv5j1201	446	17	or	or	CC
cord-022561-rv5j1201	446	18	eccentrocytes	eccentrocyte	NNS
cord-022561-rv5j1201	446	19	or	or	CC
cord-022561-rv5j1201	446	20	on	on	IN
cord-022561-rv5j1201	446	21	gross	gross	JJ
cord-022561-rv5j1201	446	22	examination	examination	NN
cord-022561-rv5j1201	446	23	as	as	IN
cord-022561-rv5j1201	446	24	methemoglobinemia	methemoglobinemia	NN
cord-022561-rv5j1201	446	25	.	.	.
cord-022561-rv5j1201	447	1	Heinz	Heinz	NNP
cord-022561-rv5j1201	447	2	bodies	body	NNS
cord-022561-rv5j1201	447	3	are	be	VBP
cord-022561-rv5j1201	447	4	foci	foci	JJ
cord-022561-rv5j1201	447	5	of	of	IN
cord-022561-rv5j1201	447	6	denatured	denatured	JJ
cord-022561-rv5j1201	447	7	globin	globin	NN
cord-022561-rv5j1201	447	8	that	that	WDT
cord-022561-rv5j1201	447	9	interact	interact	VBP
cord-022561-rv5j1201	447	10	with	with	IN
cord-022561-rv5j1201	447	11	the	the	DT
cord-022561-rv5j1201	447	12	erythrocyte	erythrocyte	NN
cord-022561-rv5j1201	447	13	membrane	membrane	NN
cord-022561-rv5j1201	447	14	.	.	.
cord-022561-rv5j1201	448	1	They	-PRON-	PRP
cord-022561-rv5j1201	448	2	are	be	VBP
cord-022561-rv5j1201	448	3	usually	usually	RB
cord-022561-rv5j1201	448	4	subtly	subtly	RB
cord-022561-rv5j1201	448	5	evident	evident	JJ
cord-022561-rv5j1201	448	6	on	on	IN
cord-022561-rv5j1201	448	7	routine	routine	JJ
cord-022561-rv5j1201	448	8	Wright	Wright	NNP
cord-022561-rv5j1201	448	9	-	-	HYPH
cord-022561-rv5j1201	448	10	stained	stain	VBN
cord-022561-rv5j1201	448	11	blood	blood	NN
cord-022561-rv5j1201	448	12	smears	smear	NNS
cord-022561-rv5j1201	448	13	as	as	IN
cord-022561-rv5j1201	448	14	pale	pale	JJ
cord-022561-rv5j1201	448	15	circular	circular	JJ
cord-022561-rv5j1201	448	16	inclusions	inclusion	NNS
cord-022561-rv5j1201	448	17	or	or	CC
cord-022561-rv5j1201	448	18	blunt	blunt	JJ
cord-022561-rv5j1201	448	19	,	,	,
cord-022561-rv5j1201	448	20	rounded	rounded	JJ
cord-022561-rv5j1201	448	21	protrusions	protrusion	NNS
cord-022561-rv5j1201	448	22	of	of	IN
cord-022561-rv5j1201	448	23	the	the	DT
cord-022561-rv5j1201	448	24	cell	cell	NN
cord-022561-rv5j1201	448	25	margin	margin	NN
cord-022561-rv5j1201	448	26	but	but	CC
cord-022561-rv5j1201	448	27	are	be	VBP
cord-022561-rv5j1201	448	28	readily	readily	RB
cord-022561-rv5j1201	448	29	discernible	discernible	JJ
cord-022561-rv5j1201	448	30	on	on	IN
cord-022561-rv5j1201	448	31	smears	smear	NNS
cord-022561-rv5j1201	448	32	stained	stain	VBN
cord-022561-rv5j1201	448	33	with	with	IN
cord-022561-rv5j1201	448	34	new	new	JJ
cord-022561-rv5j1201	448	35	methylene	methylene	NN
cord-022561-rv5j1201	448	36	blue	blue	NN
cord-022561-rv5j1201	448	37	.	.	.
cord-022561-rv5j1201	449	1	Cats	cat	NNS
cord-022561-rv5j1201	449	2	are	be	VBP
cord-022561-rv5j1201	449	3	particularly	particularly	RB
cord-022561-rv5j1201	449	4	susceptible	susceptible	JJ
cord-022561-rv5j1201	449	5	to	to	IN
cord-022561-rv5j1201	449	6	Heinz	Heinz	NNP
cord-022561-rv5j1201	449	7	body	body	NN
cord-022561-rv5j1201	449	8	formation	formation	NN
cord-022561-rv5j1201	449	9	and	and	CC
cord-022561-rv5j1201	449	10	may	may	MD
cord-022561-rv5j1201	449	11	have	have	VB
cord-022561-rv5j1201	449	12	low	low	JJ
cord-022561-rv5j1201	449	13	numbers	number	NNS
cord-022561-rv5j1201	449	14	of	of	IN
cord-022561-rv5j1201	449	15	Heinz	Heinz	NNP
cord-022561-rv5j1201	449	16	bodies	body	NNS
cord-022561-rv5j1201	449	17	normally	normally	RB
cord-022561-rv5j1201	449	18	.	.	.
cord-022561-rv5j1201	450	1	There	there	EX
cord-022561-rv5j1201	450	2	is	be	VBZ
cord-022561-rv5j1201	450	3	no	no	DT
cord-022561-rv5j1201	450	4	unanimity	unanimity	NN
cord-022561-rv5j1201	450	5	of	of	IN
cord-022561-rv5j1201	450	6	opinion	opinion	NN
cord-022561-rv5j1201	450	7	,	,	,
cord-022561-rv5j1201	450	8	but	but	CC
cord-022561-rv5j1201	450	9	some	some	DT
cord-022561-rv5j1201	450	10	clinical	clinical	JJ
cord-022561-rv5j1201	450	11	pathologists	pathologist	NNS
cord-022561-rv5j1201	450	12	believe	believe	VBP
cord-022561-rv5j1201	450	13	that	that	IN
cord-022561-rv5j1201	450	14	the	the	DT
cord-022561-rv5j1201	450	15	presence	presence	NN
cord-022561-rv5j1201	450	16	of	of	IN
cord-022561-rv5j1201	450	17	Heinz	Heinz	NNP
cord-022561-rv5j1201	450	18	bodies	body	NNS
cord-022561-rv5j1201	450	19	in	in	IN
cord-022561-rv5j1201	450	20	up	up	IN
cord-022561-rv5j1201	450	21	to	to	TO
cord-022561-rv5j1201	450	22	10	10	CD
cord-022561-rv5j1201	450	23	%	%	NN
cord-022561-rv5j1201	450	24	of	of	IN
cord-022561-rv5j1201	450	25	all	all	DT
cord-022561-rv5j1201	450	26	erythrocytes	erythrocyte	NNS
cord-022561-rv5j1201	450	27	in	in	IN
cord-022561-rv5j1201	450	28	cats	cat	NNS
cord-022561-rv5j1201	450	29	is	be	VBZ
cord-022561-rv5j1201	450	30	within	within	IN
cord-022561-rv5j1201	450	31	normal	normal	JJ
cord-022561-rv5j1201	450	32	limits	limit	NNS
cord-022561-rv5j1201	450	33	.	.	.
cord-022561-rv5j1201	451	1	This	this	DT
cord-022561-rv5j1201	451	2	predisposition	predisposition	NN
cord-022561-rv5j1201	451	3	is	be	VBZ
cord-022561-rv5j1201	451	4	believed	believe	VBN
cord-022561-rv5j1201	451	5	to	to	TO
cord-022561-rv5j1201	451	6	reflect	reflect	VB
cord-022561-rv5j1201	451	7	unique	unique	JJ
cord-022561-rv5j1201	451	8	features	feature	NNS
cord-022561-rv5j1201	451	9	of	of	IN
cord-022561-rv5j1201	451	10	the	the	DT
cord-022561-rv5j1201	451	11	feline	feline	JJ
cord-022561-rv5j1201	451	12	erythrocyte	erythrocyte	NN
cord-022561-rv5j1201	451	13	,	,	,
cord-022561-rv5j1201	451	14	whose	whose	WP$
cord-022561-rv5j1201	451	15	hemoglobin	hemoglobin	NN
cord-022561-rv5j1201	451	16	has	have	VBZ
cord-022561-rv5j1201	451	17	more	more	JJR
cord-022561-rv5j1201	451	18	sulfhydryl	sulfhydryl	NN
cord-022561-rv5j1201	451	19	groups	group	NNS
cord-022561-rv5j1201	451	20	(	(	-LRB-
cord-022561-rv5j1201	451	21	preferential	preferential	JJ
cord-022561-rv5j1201	451	22	sites	site	NNS
cord-022561-rv5j1201	451	23	for	for	IN
cord-022561-rv5j1201	451	24	oxidative	oxidative	JJ
cord-022561-rv5j1201	451	25	damage	damage	NN
cord-022561-rv5j1201	451	26	)	)	-RRB-
cord-022561-rv5j1201	451	27	than	than	IN
cord-022561-rv5j1201	451	28	do	do	VB
cord-022561-rv5j1201	451	29	erythrocytes	erythrocyte	NNS
cord-022561-rv5j1201	451	30	of	of	IN
cord-022561-rv5j1201	451	31	other	other	JJ
cord-022561-rv5j1201	451	32	species	specie	NNS
cord-022561-rv5j1201	451	33	and	and	CC
cord-022561-rv5j1201	451	34	may	may	MD
cord-022561-rv5j1201	451	35	also	also	RB
cord-022561-rv5j1201	451	36	have	have	VB
cord-022561-rv5j1201	451	37	lower	low	JJR
cord-022561-rv5j1201	451	38	intrinsic	intrinsic	JJ
cord-022561-rv5j1201	451	39	reducing	reduce	VBG
cord-022561-rv5j1201	451	40	capacity	capacity	NN
cord-022561-rv5j1201	451	41	.	.	.
cord-022561-rv5j1201	452	1	It	-PRON-	PRP
cord-022561-rv5j1201	452	2	is	be	VBZ
cord-022561-rv5j1201	452	3	also	also	RB
cord-022561-rv5j1201	452	4	possible	possible	JJ
cord-022561-rv5j1201	452	5	that	that	IN
cord-022561-rv5j1201	452	6	the	the	DT
cord-022561-rv5j1201	452	7	feline	feline	JJ
cord-022561-rv5j1201	452	8	spleen	spleen	NN
cord-022561-rv5j1201	452	9	does	do	VBZ
cord-022561-rv5j1201	452	10	not	not	RB
cord-022561-rv5j1201	452	11	have	have	VB
cord-022561-rv5j1201	452	12	as	as	RB
cord-022561-rv5j1201	452	13	efficient	efficient	JJ
cord-022561-rv5j1201	452	14	a	a	DT
cord-022561-rv5j1201	452	15	"	"	``
cord-022561-rv5j1201	452	16	pitting	pit	VBG
cord-022561-rv5j1201	452	17	"	"	''
cord-022561-rv5j1201	452	18	function	function	NN
cord-022561-rv5j1201	452	19	(	(	-LRB-
cord-022561-rv5j1201	452	20	splenic	splenic	JJ
cord-022561-rv5j1201	452	21	structure	structure	NN
cord-022561-rv5j1201	452	22	and	and	CC
cord-022561-rv5j1201	452	23	function	function	NN
cord-022561-rv5j1201	452	24	are	be	VBP
cord-022561-rv5j1201	452	25	discussed	discuss	VBN
cord-022561-rv5j1201	452	26	in	in	IN
cord-022561-rv5j1201	452	27	more	more	JJR
cord-022561-rv5j1201	452	28	detail	detail	NN
cord-022561-rv5j1201	452	29	later	later	RB
cord-022561-rv5j1201	452	30	in	in	IN
cord-022561-rv5j1201	452	31	this	this	DT
cord-022561-rv5j1201	452	32	chapter	chapter	NN
cord-022561-rv5j1201	452	33	)	)	-RRB-
cord-022561-rv5j1201	452	34	.	.	.
cord-022561-rv5j1201	453	1	Eccentrocytes	eccentrocyte	NNS
cord-022561-rv5j1201	453	2	,	,	,
cord-022561-rv5j1201	453	3	evident	evident	JJ
cord-022561-rv5j1201	453	4	as	as	IN
cord-022561-rv5j1201	453	5	erythrocytes	erythrocyte	NNS
cord-022561-rv5j1201	453	6	in	in	IN
cord-022561-rv5j1201	453	7	which	which	WDT
cord-022561-rv5j1201	453	8	one	one	CD
cord-022561-rv5j1201	453	9	side	side	NN
cord-022561-rv5j1201	453	10	of	of	IN
cord-022561-rv5j1201	453	11	the	the	DT
cord-022561-rv5j1201	453	12	cell	cell	NN
cord-022561-rv5j1201	453	13	has	have	VBZ
cord-022561-rv5j1201	453	14	increased	increase	VBN
cord-022561-rv5j1201	453	15	pallor	pallor	NN
cord-022561-rv5j1201	453	16	(	(	-LRB-
cord-022561-rv5j1201	453	17	Fig	Fig	NNP
cord-022561-rv5j1201	453	18	.	.	.
cord-022561-rv5j1201	453	19	13	13	CD
cord-022561-rv5j1201	453	20	-	-	SYM
cord-022561-rv5j1201	453	21	15	15	CD
cord-022561-rv5j1201	453	22	,	,	,
cord-022561-rv5j1201	453	23	A	A	NNP
cord-022561-rv5j1201	453	24	)	)	-RRB-
cord-022561-rv5j1201	453	25	,	,	,
cord-022561-rv5j1201	453	26	are	be	VBP
cord-022561-rv5j1201	453	27	another	another	DT
cord-022561-rv5j1201	453	28	manifestation	manifestation	NN
cord-022561-rv5j1201	453	29	of	of	IN
cord-022561-rv5j1201	453	30	oxidative	oxidative	JJ
cord-022561-rv5j1201	453	31	damage	damage	NN
cord-022561-rv5j1201	453	32	.	.	.
cord-022561-rv5j1201	454	1	They	-PRON-	PRP
cord-022561-rv5j1201	454	2	form	form	VBP
cord-022561-rv5j1201	454	3	because	because	IN
cord-022561-rv5j1201	454	4	of	of	IN
cord-022561-rv5j1201	454	5	cross	cross	NN
cord-022561-rv5j1201	454	6	-	-	NN
cord-022561-rv5j1201	454	7	linking	linking	NN
cord-022561-rv5j1201	454	8	of	of	IN
cord-022561-rv5j1201	454	9	total	total	JJ
cord-022561-rv5j1201	454	10	hemoglobin	hemoglobin	NN
cord-022561-rv5j1201	454	11	)	)	-RRB-
cord-022561-rv5j1201	454	12	,	,	,
cord-022561-rv5j1201	454	13	methemoglobin	methemoglobin	NNP
cord-022561-rv5j1201	454	14	imparts	impart	VBZ
cord-022561-rv5j1201	454	15	a	a	DT
cord-022561-rv5j1201	454	16	grossly	grossly	RB
cord-022561-rv5j1201	454	17	discernible	discernible	JJ
cord-022561-rv5j1201	454	18	chocolate	chocolate	NN
cord-022561-rv5j1201	454	19	color	color	NN
cord-022561-rv5j1201	454	20	to	to	IN
cord-022561-rv5j1201	454	21	the	the	DT
cord-022561-rv5j1201	454	22	blood	blood	NN
cord-022561-rv5j1201	454	23	.	.	.
cord-022561-rv5j1201	455	1	By	by	IN
cord-022561-rv5j1201	455	2	itself	-PRON-	PRP
cord-022561-rv5j1201	455	3	,	,	,
cord-022561-rv5j1201	455	4	mechanical	mechanical	JJ
cord-022561-rv5j1201	455	5	fragmentation	fragmentation	NN
cord-022561-rv5j1201	455	6	hemolysis	hemolysis	NN
cord-022561-rv5j1201	455	7	tends	tend	VBZ
cord-022561-rv5j1201	455	8	to	to	TO
cord-022561-rv5j1201	455	9	cause	cause	VB
cord-022561-rv5j1201	455	10	mild	mild	JJ
cord-022561-rv5j1201	455	11	or	or	CC
cord-022561-rv5j1201	455	12	no	no	DT
cord-022561-rv5j1201	455	13	anemia	anemia	NN
cord-022561-rv5j1201	455	14	.	.	.
cord-022561-rv5j1201	456	1	Mechanical	mechanical	JJ
cord-022561-rv5j1201	456	2	fragmentation	fragmentation	NN
cord-022561-rv5j1201	456	3	results	result	VBZ
cord-022561-rv5j1201	456	4	from	from	IN
cord-022561-rv5j1201	456	5	trauma	trauma	NN
cord-022561-rv5j1201	456	6	or	or	CC
cord-022561-rv5j1201	456	7	shearing	shearing	NN
cord-022561-rv5j1201	456	8	of	of	IN
cord-022561-rv5j1201	456	9	erythrocytes	erythrocyte	NNS
cord-022561-rv5j1201	456	10	within	within	IN
cord-022561-rv5j1201	456	11	blood	blood	NN
cord-022561-rv5j1201	456	12	vessels	vessel	NNS
cord-022561-rv5j1201	456	13	.	.	.
cord-022561-rv5j1201	457	1	Normal	normal	JJ
cord-022561-rv5j1201	457	2	erythrocytes	erythrocyte	NNS
cord-022561-rv5j1201	457	3	may	may	MD
cord-022561-rv5j1201	457	4	be	be	VB
cord-022561-rv5j1201	457	5	flowing	flow	VBG
cord-022561-rv5j1201	457	6	through	through	IN
cord-022561-rv5j1201	457	7	abnormal	abnormal	JJ
cord-022561-rv5j1201	457	8	vasculature	vasculature	NN
cord-022561-rv5j1201	457	9	,	,	,
cord-022561-rv5j1201	457	10	such	such	JJ
cord-022561-rv5j1201	457	11	as	as	IN
cord-022561-rv5j1201	457	12	with	with	IN
cord-022561-rv5j1201	457	13	heart	heart	NN
cord-022561-rv5j1201	457	14	valve	valve	NN
cord-022561-rv5j1201	457	15	defects	defect	NNS
cord-022561-rv5j1201	457	16	,	,	,
cord-022561-rv5j1201	457	17	intravascular	intravascular	JJ
cord-022561-rv5j1201	457	18	fibrin	fibrin	NN
cord-022561-rv5j1201	457	19	deposition	deposition	NN
cord-022561-rv5j1201	457	20	(	(	-LRB-
cord-022561-rv5j1201	457	21	e.g.	e.g.	RB
cord-022561-rv5j1201	457	22	,	,	,
cord-022561-rv5j1201	457	23	disseminated	disseminate	VBN
cord-022561-rv5j1201	457	24	intravascular	intravascular	JJ
cord-022561-rv5j1201	457	25	coagulation	coagulation	NN
cord-022561-rv5j1201	457	26	)	)	-RRB-
cord-022561-rv5j1201	457	27	,	,	,
cord-022561-rv5j1201	457	28	vasculitis	vasculitis	NN
cord-022561-rv5j1201	457	29	,	,	,
cord-022561-rv5j1201	457	30	or	or	CC
cord-022561-rv5j1201	457	31	hemangiosarcoma	hemangiosarcoma	NN
cord-022561-rv5j1201	457	32	.	.	.
cord-022561-rv5j1201	458	1	Alternatively	alternatively	RB
cord-022561-rv5j1201	458	2	,	,	,
cord-022561-rv5j1201	458	3	the	the	DT
cord-022561-rv5j1201	458	4	red	red	JJ
cord-022561-rv5j1201	458	5	blood	blood	NN
cord-022561-rv5j1201	458	6	cells	cell	NNS
cord-022561-rv5j1201	458	7	may	may	MD
cord-022561-rv5j1201	458	8	be	be	VB
cord-022561-rv5j1201	458	9	particularly	particularly	RB
cord-022561-rv5j1201	458	10	fragile	fragile	JJ
cord-022561-rv5j1201	458	11	within	within	IN
cord-022561-rv5j1201	458	12	normal	normal	JJ
cord-022561-rv5j1201	458	13	blood	blood	NN
cord-022561-rv5j1201	458	14	vasculature	vasculature	NN
cord-022561-rv5j1201	458	15	,	,	,
cord-022561-rv5j1201	458	16	as	as	IN
cord-022561-rv5j1201	458	17	occurs	occur	VBZ
cord-022561-rv5j1201	458	18	with	with	IN
cord-022561-rv5j1201	458	19	iron	iron	NN
cord-022561-rv5j1201	458	20	deficiency	deficiency	NN
cord-022561-rv5j1201	458	21	.	.	.
cord-022561-rv5j1201	459	1	In	in	IN
cord-022561-rv5j1201	459	2	either	either	DT
cord-022561-rv5j1201	459	3	instance	instance	NN
cord-022561-rv5j1201	459	4	,	,	,
cord-022561-rv5j1201	459	5	microscopic	microscopic	JJ
cord-022561-rv5j1201	459	6	evidence	evidence	NN
cord-022561-rv5j1201	459	7	of	of	IN
cord-022561-rv5j1201	459	8	mechanical	mechanical	JJ
cord-022561-rv5j1201	459	9	fragmentation	fragmentation	NN
cord-022561-rv5j1201	459	10	includes	include	VBZ
cord-022561-rv5j1201	459	11	the	the	DT
cord-022561-rv5j1201	459	12	presence	presence	NN
cord-022561-rv5j1201	459	13	of	of	IN
cord-022561-rv5j1201	459	14	erythrocyte	erythrocyte	NN
cord-022561-rv5j1201	459	15	fragments	fragment	NNS
cord-022561-rv5j1201	459	16	(	(	-LRB-
cord-022561-rv5j1201	459	17	schistocytes	schistocytes	NNP
cord-022561-rv5j1201	459	18	[	[	-LRB-
cord-022561-rv5j1201	459	19	see	see	VB
cord-022561-rv5j1201	459	20	Fig	Fig	NNP
cord-022561-rv5j1201	459	21	.	.	.
cord-022561-rv5j1201	459	22	 	 	_SP
cord-022561-rv5j1201	460	1	13	13	CD
cord-022561-rv5j1201	460	2	-15	-15	CD
cord-022561-rv5j1201	460	3	,	,	,
cord-022561-rv5j1201	460	4	C	C	NNP
cord-022561-rv5j1201	460	5	]	]	-RRB-
cord-022561-rv5j1201	460	6	)	)	-RRB-
cord-022561-rv5j1201	460	7	,	,	,
cord-022561-rv5j1201	460	8	erythrocytes	erythrocyte	NNS
cord-022561-rv5j1201	460	9	with	with	IN
cord-022561-rv5j1201	460	10	irregular	irregular	JJ
cord-022561-rv5j1201	460	11	cytoplasmic	cytoplasmic	JJ
cord-022561-rv5j1201	460	12	projections	projection	NNS
cord-022561-rv5j1201	460	13	(	(	-LRB-
cord-022561-rv5j1201	460	14	acanthocytes	acanthocytes	NNP
cord-022561-rv5j1201	460	15	)	)	-RRB-
cord-022561-rv5j1201	460	16	,	,	,
cord-022561-rv5j1201	460	17	erythrocytes	erythrocyte	NNS
cord-022561-rv5j1201	460	18	with	with	IN
cord-022561-rv5j1201	460	19	blister	blister	NN
cord-022561-rv5j1201	460	20	-	-	HYPH
cord-022561-rv5j1201	460	21	like	like	JJ
cord-022561-rv5j1201	460	22	projections	projection	NNS
cord-022561-rv5j1201	460	23	(	(	-LRB-
cord-022561-rv5j1201	460	24	keratocytes	keratocytes	NNP
cord-022561-rv5j1201	460	25	)	)	-RRB-
cord-022561-rv5j1201	460	26	,	,	,
cord-022561-rv5j1201	460	27	or	or	CC
cord-022561-rv5j1201	460	28	ghost	ghost	NN
cord-022561-rv5j1201	460	29	cells	cell	NNS
cord-022561-rv5j1201	460	30	(	(	-LRB-
cord-022561-rv5j1201	460	31	see	see	VB
cord-022561-rv5j1201	460	32	Figs	fig	NNS
cord-022561-rv5j1201	460	33	.	.	.
cord-022561-rv5j1201	461	1	13	13	CD
cord-022561-rv5j1201	461	2	-	-	SYM
cord-022561-rv5j1201	461	3	13	13	CD
cord-022561-rv5j1201	461	4	,	,	,
cord-022561-rv5j1201	461	5	A	A	NNP
cord-022561-rv5j1201	461	6	,	,	,
cord-022561-rv5j1201	461	7	13	13	CD
cord-022561-rv5j1201	461	8	-	-	SYM
cord-022561-rv5j1201	461	9	15	15	CD
cord-022561-rv5j1201	461	10	,	,	,
cord-022561-rv5j1201	461	11	D	D	NNP
cord-022561-rv5j1201	461	12	,	,	,
cord-022561-rv5j1201	461	13	and	and	CC
cord-022561-rv5j1201	461	14	13	13	CD
cord-022561-rv5j1201	461	15	-	-	SYM
cord-022561-rv5j1201	461	16	15	15	CD
cord-022561-rv5j1201	461	17	,	,	,
cord-022561-rv5j1201	461	18	E	E	NNP
cord-022561-rv5j1201	461	19	)	)	-RRB-
cord-022561-rv5j1201	461	20	.	.	.
cord-022561-rv5j1201	462	1	membrane	membrane	NN
cord-022561-rv5j1201	462	2	proteins	protein	NNS
cord-022561-rv5j1201	462	3	,	,	,
cord-022561-rv5j1201	462	4	with	with	IN
cord-022561-rv5j1201	462	5	adhesion	adhesion	NN
cord-022561-rv5j1201	462	6	of	of	IN
cord-022561-rv5j1201	462	7	opposing	oppose	VBG
cord-022561-rv5j1201	462	8	areas	area	NNS
cord-022561-rv5j1201	462	9	of	of	IN
cord-022561-rv5j1201	462	10	the	the	DT
cord-022561-rv5j1201	462	11	cell	cell	NN
cord-022561-rv5j1201	462	12	's	's	POS
cord-022561-rv5j1201	462	13	inner	inner	JJ
cord-022561-rv5j1201	462	14	membrane	membrane	NN
cord-022561-rv5j1201	462	15	leaflet	leaflet	NN
cord-022561-rv5j1201	462	16	,	,	,
cord-022561-rv5j1201	462	17	and	and	CC
cord-022561-rv5j1201	462	18	displacement	displacement	NN
cord-022561-rv5j1201	462	19	of	of	IN
cord-022561-rv5j1201	462	20	most	most	JJS
cord-022561-rv5j1201	462	21	of	of	IN
cord-022561-rv5j1201	462	22	the	the	DT
cord-022561-rv5j1201	462	23	hemoglobin	hemoglobin	NN
cord-022561-rv5j1201	462	24	toward	toward	IN
cord-022561-rv5j1201	462	25	the	the	DT
cord-022561-rv5j1201	462	26	other	other	JJ
cord-022561-rv5j1201	462	27	side	side	NN
cord-022561-rv5j1201	462	28	.	.	.
cord-022561-rv5j1201	463	1	The	the	DT
cord-022561-rv5j1201	463	2	fused	fuse	VBN
cord-022561-rv5j1201	463	3	membranes	membrane	NNS
cord-022561-rv5j1201	463	4	may	may	MD
cord-022561-rv5j1201	463	5	fragment	fragment	VB
cord-022561-rv5j1201	463	6	off	off	IN
cord-022561-rv5j1201	463	7	of	of	IN
cord-022561-rv5j1201	463	8	the	the	DT
cord-022561-rv5j1201	463	9	eccentrocyte	eccentrocyte	NNP
cord-022561-rv5j1201	463	10	,	,	,
cord-022561-rv5j1201	463	11	leaving	leave	VBG
cord-022561-rv5j1201	463	12	a	a	DT
cord-022561-rv5j1201	463	13	slightly	slightly	RB
cord-022561-rv5j1201	463	14	ruffled	ruffle	VBN
cord-022561-rv5j1201	463	15	border	border	NN
cord-022561-rv5j1201	463	16	;	;	:
cord-022561-rv5j1201	463	17	this	this	DT
cord-022561-rv5j1201	463	18	cellular	cellular	JJ
cord-022561-rv5j1201	463	19	morphologic	morphologic	JJ
cord-022561-rv5j1201	463	20	abnormality	abnormality	NN
cord-022561-rv5j1201	463	21	is	be	VBZ
cord-022561-rv5j1201	463	22	called	call	VBN
cord-022561-rv5j1201	463	23	a	a	DT
cord-022561-rv5j1201	463	24	pyknocyte	pyknocyte	NN
cord-022561-rv5j1201	463	25	(	(	-LRB-
cord-022561-rv5j1201	463	26	see	see	VB
cord-022561-rv5j1201	463	27	Fig	Fig	NNP
cord-022561-rv5j1201	463	28	.	.	.
cord-022561-rv5j1201	464	1	13	13	CD
cord-022561-rv5j1201	464	2	-	-	SYM
cord-022561-rv5j1201	464	3	15	15	CD
cord-022561-rv5j1201	464	4	,	,	,
cord-022561-rv5j1201	464	5	B	b	NN
cord-022561-rv5j1201	464	6	)	)	-RRB-
cord-022561-rv5j1201	464	7	.	.	.
cord-022561-rv5j1201	465	1	Oxidative	oxidative	JJ
cord-022561-rv5j1201	465	2	insult	insult	NN
cord-022561-rv5j1201	465	3	may	may	MD
cord-022561-rv5j1201	465	4	also	also	RB
cord-022561-rv5j1201	465	5	result	result	VB
cord-022561-rv5j1201	465	6	in	in	IN
cord-022561-rv5j1201	465	7	conversion	conversion	NN
cord-022561-rv5j1201	465	8	of	of	IN
cord-022561-rv5j1201	465	9	hemoglobin	hemoglobin	NN
cord-022561-rv5j1201	465	10	(	(	-LRB-
cord-022561-rv5j1201	465	11	iron	iron	NN
cord-022561-rv5j1201	465	12	in	in	IN
cord-022561-rv5j1201	465	13	the	the	DT
cord-022561-rv5j1201	465	14	Fe	Fe	NNP
cord-022561-rv5j1201	465	15	2	2	CD
cord-022561-rv5j1201	465	16	+	+	CD
cord-022561-rv5j1201	465	17	state	state	NN
cord-022561-rv5j1201	465	18	)	)	-RRB-
cord-022561-rv5j1201	465	19	to	to	IN
cord-022561-rv5j1201	465	20	methemoglobin	methemoglobin	NNP
cord-022561-rv5j1201	465	21	(	(	-LRB-
cord-022561-rv5j1201	465	22	iron	iron	NN
cord-022561-rv5j1201	465	23	in	in	IN
cord-022561-rv5j1201	465	24	the	the	DT
cord-022561-rv5j1201	465	25	Fe	Fe	NNP
cord-022561-rv5j1201	465	26	3	3	CD
cord-022561-rv5j1201	465	27	+	+	CC
cord-022561-rv5j1201	465	28	state	state	NN
cord-022561-rv5j1201	465	29	)	)	-RRB-
cord-022561-rv5j1201	465	30	,	,	,
cord-022561-rv5j1201	465	31	which	which	WDT
cord-022561-rv5j1201	465	32	is	be	VBZ
cord-022561-rv5j1201	465	33	incapable	incapable	JJ
cord-022561-rv5j1201	465	34	of	of	IN
cord-022561-rv5j1201	465	35	binding	bind	VBG
cord-022561-rv5j1201	465	36	oxygen	oxygen	NN
cord-022561-rv5j1201	465	37	.	.	.
cord-022561-rv5j1201	466	1	Methemoglobin	Methemoglobin	NNP
cord-022561-rv5j1201	466	2	is	be	VBZ
cord-022561-rv5j1201	466	3	produced	produce	VBN
cord-022561-rv5j1201	466	4	normally	normally	RB
cord-022561-rv5j1201	466	5	in	in	IN
cord-022561-rv5j1201	466	6	small	small	JJ
cord-022561-rv5j1201	466	7	amounts	amount	NNS
cord-022561-rv5j1201	466	8	but	but	CC
cord-022561-rv5j1201	466	9	reduced	reduce	VBN
cord-022561-rv5j1201	466	10	back	back	RB
cord-022561-rv5j1201	466	11	to	to	IN
cord-022561-rv5j1201	466	12	oxyhemoglobin	oxyhemoglobin	NNP
cord-022561-rv5j1201	466	13	by	by	IN
cord-022561-rv5j1201	466	14	the	the	DT
cord-022561-rv5j1201	466	15	enzyme	enzyme	NN
cord-022561-rv5j1201	466	16	cytochrome	cytochrome	NN
cord-022561-rv5j1201	466	17	-	-	HYPH
cord-022561-rv5j1201	466	18	b	b	NN
cord-022561-rv5j1201	466	19	5	5	CD
cord-022561-rv5j1201	466	20	reductase	reductase	NN
cord-022561-rv5j1201	466	21	(	(	-LRB-
cord-022561-rv5j1201	466	22	also	also	RB
cord-022561-rv5j1201	466	23	known	know	VBN
cord-022561-rv5j1201	466	24	as	as	IN
cord-022561-rv5j1201	466	25	methemoglobin	methemoglobin	NNP
cord-022561-rv5j1201	466	26	reductase	reductase	NNP
cord-022561-rv5j1201	466	27	)	)	-RRB-
cord-022561-rv5j1201	466	28	.	.	.
cord-022561-rv5j1201	467	1	Methemoglobinemia	Methemoglobinemia	NNP
cord-022561-rv5j1201	467	2	results	result	NNS
cord-022561-rv5j1201	467	3	when	when	WRB
cord-022561-rv5j1201	467	4	methemoglobin	methemoglobin	NNP
cord-022561-rv5j1201	467	5	is	be	VBZ
cord-022561-rv5j1201	467	6	produced	produce	VBN
cord-022561-rv5j1201	467	7	in	in	IN
cord-022561-rv5j1201	467	8	excessive	excessive	JJ
cord-022561-rv5j1201	467	9	amounts	amount	NNS
cord-022561-rv5j1201	467	10	(	(	-LRB-
cord-022561-rv5j1201	467	11	because	because	IN
cord-022561-rv5j1201	467	12	of	of	IN
cord-022561-rv5j1201	467	13	oxidative	oxidative	JJ
cord-022561-rv5j1201	467	14	insult	insult	NN
cord-022561-rv5j1201	467	15	)	)	-RRB-
cord-022561-rv5j1201	467	16	or	or	CC
cord-022561-rv5j1201	467	17	when	when	WRB
cord-022561-rv5j1201	467	18	the	the	DT
cord-022561-rv5j1201	467	19	normal	normal	JJ
cord-022561-rv5j1201	467	20	pathways	pathway	NNS
cord-022561-rv5j1201	467	21	for	for	IN
cord-022561-rv5j1201	467	22	maintaining	maintain	VBG
cord-022561-rv5j1201	467	23	hemoglobin	hemoglobin	NN
cord-022561-rv5j1201	467	24	in	in	IN
cord-022561-rv5j1201	467	25	the	the	DT
cord-022561-rv5j1201	467	26	Fe	Fe	NNP
cord-022561-rv5j1201	467	27	2	2	CD
cord-022561-rv5j1201	467	28	+	+	CD
cord-022561-rv5j1201	467	29	state	state	NN
cord-022561-rv5j1201	467	30	are	be	VBP
cord-022561-rv5j1201	467	31	impaired	impair	VBN
cord-022561-rv5j1201	467	32	(	(	-LRB-
cord-022561-rv5j1201	467	33	as	as	IN
cord-022561-rv5j1201	467	34	in	in	IN
cord-022561-rv5j1201	467	35	cytochrome	cytochrome	NN
cord-022561-rv5j1201	467	36	-	-	HYPH
cord-022561-rv5j1201	467	37	b	b	NN
cord-022561-rv5j1201	467	38	5	5	CD
cord-022561-rv5j1201	467	39	reductase	reductase	NN
cord-022561-rv5j1201	467	40	deficiency	deficiency	NN
cord-022561-rv5j1201	467	41	)	)	-RRB-
cord-022561-rv5j1201	467	42	.	.	.
cord-022561-rv5j1201	468	1	When	when	WRB
cord-022561-rv5j1201	468	2	present	present	JJ
cord-022561-rv5j1201	468	3	in	in	IN
cord-022561-rv5j1201	468	4	sufficiently	sufficiently	RB
cord-022561-rv5j1201	468	5	high	high	JJ
cord-022561-rv5j1201	468	6	concentration	concentration	NN
cord-022561-rv5j1201	468	7	(	(	-LRB-
cord-022561-rv5j1201	468	8	approximately	approximately	RB
cord-022561-rv5j1201	468	9	10	10	CD
cord-022561-rv5j1201	468	10	%	%	NN
cord-022561-rv5j1201	468	11	of	of	IN
cord-022561-rv5j1201	468	12	degradation	degradation	NN
cord-022561-rv5j1201	468	13	.	.	.
cord-022561-rv5j1201	469	1	Antierythrocyte	Antierythrocyte	NNP
cord-022561-rv5j1201	469	2	antibodies	antibody	NNS
cord-022561-rv5j1201	469	3	bind	bind	VBP
cord-022561-rv5j1201	469	4	RBC	RBC	NNP
cord-022561-rv5j1201	469	5	surface	surface	NN
cord-022561-rv5j1201	469	6	antigens	antigen	NNS
cord-022561-rv5j1201	469	7	,	,	,
cord-022561-rv5j1201	469	8	resulting	result	VBG
cord-022561-rv5j1201	469	9	in	in	IN
cord-022561-rv5j1201	469	10	RBC	RBC	NNP
cord-022561-rv5j1201	469	11	opsonization	opsonization	NN
cord-022561-rv5j1201	469	12	by	by	IN
cord-022561-rv5j1201	469	13	immunoglobulins	immunoglobulin	NNS
cord-022561-rv5j1201	469	14	(	(	-LRB-
cord-022561-rv5j1201	469	15	mainly	mainly	RB
cord-022561-rv5j1201	469	16	immunoglobulin	immunoglobulin	NN
cord-022561-rv5j1201	469	17	G	G	NNP
cord-022561-rv5j1201	469	18	[	[	-LRB-
cord-022561-rv5j1201	469	19	IgG	IgG	NNP
cord-022561-rv5j1201	469	20	]	]	-RRB-
cord-022561-rv5j1201	469	21	)	)	-RRB-
cord-022561-rv5j1201	469	22	and	and	CC
cord-022561-rv5j1201	469	23	complement	complement	VB
cord-022561-rv5j1201	469	24	(	(	-LRB-
cord-022561-rv5j1201	469	25	primarily	primarily	RB
cord-022561-rv5j1201	469	26	C3b	C3b	NNP
cord-022561-rv5j1201	469	27	)	)	-RRB-
cord-022561-rv5j1201	469	28	.	.	.
cord-022561-rv5j1201	470	1	Immunoglobulin	immunoglobulin	NN
cord-022561-rv5j1201	470	2	-	-	HYPH
cord-022561-rv5j1201	470	3	or	or	CC
cord-022561-rv5j1201	470	4	C3b	c3b	NN
cord-022561-rv5j1201	470	5	-	-	HYPH
cord-022561-rv5j1201	470	6	bound	bind	VBN
cord-022561-rv5j1201	470	7	RBCs	rbc	NNS
cord-022561-rv5j1201	470	8	are	be	VBP
cord-022561-rv5j1201	470	9	phagocytized	phagocytize	VBN
cord-022561-rv5j1201	470	10	and	and	CC
cord-022561-rv5j1201	470	11	digested	digest	VBN
cord-022561-rv5j1201	470	12	by	by	IN
cord-022561-rv5j1201	470	13	sinusoidal	sinusoidal	JJ
cord-022561-rv5j1201	470	14	macrophages	macrophage	NNS
cord-022561-rv5j1201	470	15	.	.	.
cord-022561-rv5j1201	471	1	2	2	LS
cord-022561-rv5j1201	471	2	,	,	,
cord-022561-rv5j1201	471	3	Spherocytes	Spherocytes	NNPS
cord-022561-rv5j1201	471	4	.	.	.
cord-022561-rv5j1201	472	1	Spherocytes	spherocyte	NNS
cord-022561-rv5j1201	472	2	form	form	VBP
cord-022561-rv5j1201	472	3	when	when	WRB
cord-022561-rv5j1201	472	4	the	the	DT
cord-022561-rv5j1201	472	5	membrane	membrane	NN
cord-022561-rv5j1201	472	6	of	of	IN
cord-022561-rv5j1201	472	7	immunoglobulin	immunoglobulin	NN
cord-022561-rv5j1201	472	8	-	-	:
cord-022561-rv5j1201	472	9	or	or	CC
cord-022561-rv5j1201	472	10	C3b	c3b	NN
cord-022561-rv5j1201	472	11	-	-	HYPH
cord-022561-rv5j1201	472	12	bound	bind	VBN
cord-022561-rv5j1201	472	13	RBCs	rbc	NNS
cord-022561-rv5j1201	472	14	are	be	VBP
cord-022561-rv5j1201	472	15	phagocytized	phagocytize	VBN
cord-022561-rv5j1201	472	16	by	by	IN
cord-022561-rv5j1201	472	17	macrophages	macrophage	NNS
cord-022561-rv5j1201	472	18	,	,	,
cord-022561-rv5j1201	472	19	without	without	IN
cord-022561-rv5j1201	472	20	removing	remove	VBG
cord-022561-rv5j1201	472	21	the	the	DT
cord-022561-rv5j1201	472	22	entire	entire	JJ
cord-022561-rv5j1201	472	23	RBC	RBC	NNP
cord-022561-rv5j1201	472	24	from	from	IN
cord-022561-rv5j1201	472	25	circulation	circulation	NN
cord-022561-rv5j1201	472	26	.	.	.
cord-022561-rv5j1201	473	1	Compared	compare	VBN
cord-022561-rv5j1201	473	2	to	to	IN
cord-022561-rv5j1201	473	3	normal	normal	JJ
cord-022561-rv5j1201	473	4	erythrocytes	erythrocyte	NNS
cord-022561-rv5j1201	473	5	,	,	,
cord-022561-rv5j1201	473	6	spherocytes	spherocyte	NNS
cord-022561-rv5j1201	473	7	appear	appear	VBP
cord-022561-rv5j1201	473	8	smaller	small	JJR
cord-022561-rv5j1201	473	9	,	,	,
cord-022561-rv5j1201	473	10	more	more	RBR
cord-022561-rv5j1201	473	11	eosinophilic	eosinophilic	JJ
cord-022561-rv5j1201	473	12	,	,	,
cord-022561-rv5j1201	473	13	and	and	CC
cord-022561-rv5j1201	473	14	lack	lack	VB
cord-022561-rv5j1201	473	15	central	central	JJ
cord-022561-rv5j1201	473	16	pallor	pallor	NN
cord-022561-rv5j1201	473	17	.	.	.
cord-022561-rv5j1201	474	1	3	3	CD
cord-022561-rv5j1201	474	2	,	,	,
cord-022561-rv5j1201	474	3	RBC	RBC	NNP
cord-022561-rv5j1201	474	4	aggregation	aggregation	NN
cord-022561-rv5j1201	474	5	(	(	-LRB-
cord-022561-rv5j1201	474	6	agglutination	agglutination	NN
cord-022561-rv5j1201	474	7	)	)	-RRB-
cord-022561-rv5j1201	474	8	.	.	.
cord-022561-rv5j1201	475	1	RBC	RBC	NNP
cord-022561-rv5j1201	475	2	aggregation	aggregation	NN
cord-022561-rv5j1201	475	3	occurs	occur	VBZ
cord-022561-rv5j1201	475	4	when	when	WRB
cord-022561-rv5j1201	475	5	antierythrocyte	antierythrocyte	NNP
cord-022561-rv5j1201	475	6	immunoglobulins	immunoglobulin	NNS
cord-022561-rv5j1201	475	7	(	(	-LRB-
cord-022561-rv5j1201	475	8	immunoglobulin	immunoglobulin	NN
cord-022561-rv5j1201	475	9	M	M	NNP
cord-022561-rv5j1201	475	10	[	[	-LRB-
cord-022561-rv5j1201	475	11	IgM	IgM	NNP
cord-022561-rv5j1201	475	12	]	]	-RRB-
cord-022561-rv5j1201	475	13	or	or	CC
cord-022561-rv5j1201	475	14	high	high	JJ
cord-022561-rv5j1201	475	15	concentrations	concentration	NNS
cord-022561-rv5j1201	475	16	of	of	IN
cord-022561-rv5j1201	475	17	IgG	IgG	NNP
cord-022561-rv5j1201	475	18	)	)	-RRB-
cord-022561-rv5j1201	475	19	bind	bind	VBP
cord-022561-rv5j1201	475	20	multiple	multiple	JJ
cord-022561-rv5j1201	475	21	erythrocytes	erythrocyte	NNS
cord-022561-rv5j1201	475	22	simultaneously	simultaneously	RB
cord-022561-rv5j1201	475	23	.	.	.
cord-022561-rv5j1201	476	1	4	4	LS
cord-022561-rv5j1201	476	2	,	,	,
cord-022561-rv5j1201	476	3	Ghost	ghost	NN
cord-022561-rv5j1201	476	4	cells	cell	NNS
cord-022561-rv5j1201	476	5	.	.	.
cord-022561-rv5j1201	477	1	Antierythrocyte	Antierythrocyte	NNP
cord-022561-rv5j1201	477	2	antibodies	antibody	NNS
cord-022561-rv5j1201	477	3	bind	bind	VBP
cord-022561-rv5j1201	477	4	RBC	RBC	NNP
cord-022561-rv5j1201	477	5	surface	surface	NN
cord-022561-rv5j1201	477	6	antigens	antigen	NNS
cord-022561-rv5j1201	477	7	,	,	,
cord-022561-rv5j1201	477	8	resulting	result	VBG
cord-022561-rv5j1201	477	9	in	in	IN
cord-022561-rv5j1201	477	10	complement	complement	JJ
cord-022561-rv5j1201	477	11	activation	activation	NN
cord-022561-rv5j1201	477	12	and	and	CC
cord-022561-rv5j1201	477	13	formation	formation	NN
cord-022561-rv5j1201	477	14	of	of	IN
cord-022561-rv5j1201	477	15	the	the	DT
cord-022561-rv5j1201	477	16	membrane	membrane	NN
cord-022561-rv5j1201	477	17	attack	attack	NN
cord-022561-rv5j1201	477	18	complex	complex	NN
cord-022561-rv5j1201	477	19	(	(	-LRB-
cord-022561-rv5j1201	477	20	MAC	MAC	NNP
cord-022561-rv5j1201	477	21	)	)	-RRB-
cord-022561-rv5j1201	477	22	.	.	.
cord-022561-rv5j1201	478	1	MACs	mac	NNS
cord-022561-rv5j1201	478	2	form	form	VBP
cord-022561-rv5j1201	478	3	membrane	membrane	NN
cord-022561-rv5j1201	478	4	pores	pore	NNS
cord-022561-rv5j1201	478	5	,	,	,
cord-022561-rv5j1201	478	6	resulting	result	VBG
cord-022561-rv5j1201	478	7	in	in	IN
cord-022561-rv5j1201	478	8	rupture	rupture	NN
cord-022561-rv5j1201	478	9	of	of	IN
cord-022561-rv5j1201	478	10	RBCs	rbc	NNS
cord-022561-rv5j1201	478	11	,	,	,
cord-022561-rv5j1201	478	12	and	and	CC
cord-022561-rv5j1201	478	13	the	the	DT
cord-022561-rv5j1201	478	14	release	release	NN
cord-022561-rv5j1201	478	15	of	of	IN
cord-022561-rv5j1201	478	16	hemoglobin	hemoglobin	NN
cord-022561-rv5j1201	478	17	into	into	IN
cord-022561-rv5j1201	478	18	the	the	DT
cord-022561-rv5j1201	478	19	circulation	circulation	NN
cord-022561-rv5j1201	478	20	.	.	.
cord-022561-rv5j1201	479	1	Ghost	ghost	NN
cord-022561-rv5j1201	479	2	cells	cell	NNS
cord-022561-rv5j1201	479	3	are	be	VBP
cord-022561-rv5j1201	479	4	RBC	RBC	NNP
cord-022561-rv5j1201	479	5	membrane	membrane	NN
cord-022561-rv5j1201	479	6	remnants	remnant	NNS
cord-022561-rv5j1201	479	7	that	that	WDT
cord-022561-rv5j1201	479	8	lack	lack	VBP
cord-022561-rv5j1201	479	9	cytoplasm	cytoplasm	NN
cord-022561-rv5j1201	479	10	(	(	-LRB-
cord-022561-rv5j1201	479	11	hemoglobin	hemoglobin	NN
cord-022561-rv5j1201	479	12	normocytic	normocytic	JJ
cord-022561-rv5j1201	479	13	,	,	,
cord-022561-rv5j1201	479	14	normochromic	normochromic	JJ
cord-022561-rv5j1201	479	15	anemia	anemia	NN
cord-022561-rv5j1201	479	16	)	)	-RRB-
cord-022561-rv5j1201	479	17	.	.	.
cord-022561-rv5j1201	480	1	It	-PRON-	PRP
cord-022561-rv5j1201	480	2	has	have	VBZ
cord-022561-rv5j1201	480	3	long	long	RB
cord-022561-rv5j1201	480	4	been	be	VBN
cord-022561-rv5j1201	480	5	known	know	VBN
cord-022561-rv5j1201	480	6	that	that	IN
cord-022561-rv5j1201	480	7	patients	patient	NNS
cord-022561-rv5j1201	480	8	with	with	IN
cord-022561-rv5j1201	480	9	inflammatory	inflammatory	JJ
cord-022561-rv5j1201	480	10	or	or	CC
cord-022561-rv5j1201	480	11	other	other	JJ
cord-022561-rv5j1201	480	12	chronic	chronic	JJ
cord-022561-rv5j1201	480	13	disease	disease	NN
cord-022561-rv5j1201	480	14	often	often	RB
cord-022561-rv5j1201	480	15	become	become	VBP
cord-022561-rv5j1201	480	16	anemic	anemic	JJ
cord-022561-rv5j1201	480	17	,	,	,
cord-022561-rv5j1201	480	18	and	and	CC
cord-022561-rv5j1201	480	19	that	that	IN
cord-022561-rv5j1201	480	20	this	this	DT
cord-022561-rv5j1201	480	21	condition	condition	NN
cord-022561-rv5j1201	480	22	results	result	VBZ
cord-022561-rv5j1201	480	23	in	in	IN
cord-022561-rv5j1201	480	24	increased	increase	VBN
cord-022561-rv5j1201	480	25	iron	iron	NN
cord-022561-rv5j1201	480	26	stores	store	NNS
cord-022561-rv5j1201	480	27	in	in	IN
cord-022561-rv5j1201	480	28	the	the	DT
cord-022561-rv5j1201	480	29	bone	bone	NN
cord-022561-rv5j1201	480	30	marrow	marrow	NN
cord-022561-rv5j1201	480	31	.	.	.
cord-022561-rv5j1201	481	1	Sequestration	sequestration	NN
cord-022561-rv5j1201	481	2	of	of	IN
cord-022561-rv5j1201	481	3	iron	iron	NN
cord-022561-rv5j1201	481	4	may	may	MD
cord-022561-rv5j1201	481	5	be	be	VB
cord-022561-rv5j1201	481	6	a	a	DT
cord-022561-rv5j1201	481	7	bacteriostatic	bacteriostatic	JJ
cord-022561-rv5j1201	481	8	evolutionary	evolutionary	JJ
cord-022561-rv5j1201	481	9	adaptation	adaptation	NN
cord-022561-rv5j1201	481	10	because	because	IN
cord-022561-rv5j1201	481	11	many	many	JJ
cord-022561-rv5j1201	481	12	bacteria	bacteria	NNS
cord-022561-rv5j1201	481	13	require	require	VBP
cord-022561-rv5j1201	481	14	iron	iron	NN
cord-022561-rv5j1201	481	15	as	as	IN
cord-022561-rv5j1201	481	16	a	a	DT
cord-022561-rv5j1201	481	17	cofactor	cofactor	NN
cord-022561-rv5j1201	481	18	for	for	IN
cord-022561-rv5j1201	481	19	growth	growth	NN
cord-022561-rv5j1201	481	20	.	.	.
cord-022561-rv5j1201	482	1	In	in	IN
cord-022561-rv5j1201	482	2	recent	recent	JJ
cord-022561-rv5j1201	482	3	years	year	NNS
cord-022561-rv5j1201	482	4	,	,	,
cord-022561-rv5j1201	482	5	investigators	investigator	NNS
cord-022561-rv5j1201	482	6	have	have	VBP
cord-022561-rv5j1201	482	7	begun	begin	VBN
cord-022561-rv5j1201	482	8	to	to	TO
cord-022561-rv5j1201	482	9	elucidate	elucidate	VB
cord-022561-rv5j1201	482	10	the	the	DT
cord-022561-rv5j1201	482	11	molecular	molecular	JJ
cord-022561-rv5j1201	482	12	mechanisms	mechanism	NNS
cord-022561-rv5j1201	482	13	underlying	underlie	VBG
cord-022561-rv5j1201	482	14	anemia	anemia	NN
cord-022561-rv5j1201	482	15	of	of	IN
cord-022561-rv5j1201	482	16	inflammation	inflammation	NN
cord-022561-rv5j1201	482	17	.	.	.
cord-022561-rv5j1201	483	1	Hepcidin	Hepcidin	NNP
cord-022561-rv5j1201	483	2	,	,	,
cord-022561-rv5j1201	483	3	an	an	DT
cord-022561-rv5j1201	483	4	acute	acute	JJ
cord-022561-rv5j1201	483	5	phase	phase	NN
cord-022561-rv5j1201	483	6	protein	protein	NN
cord-022561-rv5j1201	483	7	and	and	CC
cord-022561-rv5j1201	483	8	antimicrobial	antimicrobial	JJ
cord-022561-rv5j1201	483	9	peptide	peptide	NN
cord-022561-rv5j1201	483	10	synthesized	synthesize	VBN
cord-022561-rv5j1201	483	11	in	in	IN
cord-022561-rv5j1201	483	12	the	the	DT
cord-022561-rv5j1201	483	13	liver	liver	NN
cord-022561-rv5j1201	483	14	,	,	,
cord-022561-rv5j1201	483	15	is	be	VBZ
cord-022561-rv5j1201	483	16	a	a	DT
cord-022561-rv5j1201	483	17	key	key	JJ
cord-022561-rv5j1201	483	18	mediator	mediator	NN
cord-022561-rv5j1201	483	19	that	that	WDT
cord-022561-rv5j1201	483	20	limits	limit	VBZ
cord-022561-rv5j1201	483	21	iron	iron	NN
cord-022561-rv5j1201	483	22	availability	availability	NN
cord-022561-rv5j1201	483	23	.	.	.
cord-022561-rv5j1201	484	1	Hepcidin	Hepcidin	NNP
cord-022561-rv5j1201	484	2	expression	expression	NN
cord-022561-rv5j1201	484	3	increases	increase	VBZ
cord-022561-rv5j1201	484	4	with	with	IN
cord-022561-rv5j1201	484	5	inflammation	inflammation	NN
cord-022561-rv5j1201	484	6	,	,	,
cord-022561-rv5j1201	484	7	infection	infection	NN
cord-022561-rv5j1201	484	8	,	,	,
cord-022561-rv5j1201	484	9	or	or	CC
cord-022561-rv5j1201	484	10	iron	iron	NN
cord-022561-rv5j1201	484	11	overload	overload	NN
cord-022561-rv5j1201	484	12	and	and	CC
cord-022561-rv5j1201	484	13	decreases	decrease	VBZ
cord-022561-rv5j1201	484	14	with	with	IN
cord-022561-rv5j1201	484	15	anemia	anemia	NN
cord-022561-rv5j1201	484	16	or	or	CC
cord-022561-rv5j1201	484	17	hypoxia	hypoxia	NN
cord-022561-rv5j1201	484	18	.	.	.
cord-022561-rv5j1201	485	1	Hepcidin	Hepcidin	NNP
cord-022561-rv5j1201	485	2	exerts	exert	VBZ
cord-022561-rv5j1201	485	3	its	-PRON-	PRP$
cord-022561-rv5j1201	485	4	effects	effect	NNS
cord-022561-rv5j1201	485	5	by	by	IN
cord-022561-rv5j1201	485	6	causing	cause	VBG
cord-022561-rv5j1201	485	7	functional	functional	JJ
cord-022561-rv5j1201	485	8	iron	iron	NN
cord-022561-rv5j1201	485	9	deficiency	deficiency	NN
cord-022561-rv5j1201	485	10	.	.	.
cord-022561-rv5j1201	486	1	It	-PRON-	PRP
cord-022561-rv5j1201	486	2	binds	bind	VBZ
cord-022561-rv5j1201	486	3	to	to	IN
cord-022561-rv5j1201	486	4	and	and	CC
cord-022561-rv5j1201	486	5	causes	cause	VBZ
cord-022561-rv5j1201	486	6	the	the	DT
cord-022561-rv5j1201	486	7	degradation	degradation	NN
cord-022561-rv5j1201	486	8	of	of	IN
cord-022561-rv5j1201	486	9	the	the	DT
cord-022561-rv5j1201	486	10	cell	cell	NN
cord-022561-rv5j1201	486	11	surface	surface	NN
cord-022561-rv5j1201	486	12	iron	iron	NN
cord-022561-rv5j1201	486	13	efflux	efflux	NN
cord-022561-rv5j1201	486	14	molecule	molecule	NN
cord-022561-rv5j1201	486	15	,	,	,
cord-022561-rv5j1201	486	16	ferroportin	ferroportin	NNP
cord-022561-rv5j1201	486	17	,	,	,
cord-022561-rv5j1201	486	18	thus	thus	RB
cord-022561-rv5j1201	486	19	inhibiting	inhibit	VBG
cord-022561-rv5j1201	486	20	both	both	DT
cord-022561-rv5j1201	486	21	absorption	absorption	NN
cord-022561-rv5j1201	486	22	of	of	IN
cord-022561-rv5j1201	486	23	dietary	dietary	JJ
cord-022561-rv5j1201	486	24	iron	iron	NN
cord-022561-rv5j1201	486	25	from	from	IN
cord-022561-rv5j1201	486	26	the	the	DT
cord-022561-rv5j1201	486	27	intestinal	intestinal	JJ
cord-022561-rv5j1201	486	28	epithelium	epithelium	NN
cord-022561-rv5j1201	486	29	and	and	CC
cord-022561-rv5j1201	486	30	export	export	NN
cord-022561-rv5j1201	486	31	of	of	IN
cord-022561-rv5j1201	486	32	iron	iron	NN
cord-022561-rv5j1201	486	33	from	from	IN
cord-022561-rv5j1201	486	34	macrophages	macrophage	NNS
cord-022561-rv5j1201	486	35	and	and	CC
cord-022561-rv5j1201	486	36	hepatocytes	hepatocyte	NNS
cord-022561-rv5j1201	486	37	into	into	IN
cord-022561-rv5j1201	486	38	the	the	DT
cord-022561-rv5j1201	486	39	plasma	plasma	NN
cord-022561-rv5j1201	486	40	(	(	-LRB-
cord-022561-rv5j1201	486	41	Fig	Fig	NNP
cord-022561-rv5j1201	486	42	.	.	.
cord-022561-rv5j1201	486	43	13	13	CD
cord-022561-rv5j1201	486	44	-	-	SYM
cord-022561-rv5j1201	486	45	16	16	CD
cord-022561-rv5j1201	486	46	)	)	-RRB-
cord-022561-rv5j1201	486	47	.	.	.
cord-022561-rv5j1201	487	1	Anemia	anemia	NN
cord-022561-rv5j1201	487	2	of	of	IN
cord-022561-rv5j1201	487	3	inflammation	inflammation	NN
cord-022561-rv5j1201	487	4	involves	involve	VBZ
cord-022561-rv5j1201	487	5	factors	factor	NNS
cord-022561-rv5j1201	487	6	besides	besides	IN
cord-022561-rv5j1201	487	7	decreased	decrease	VBD
cord-022561-rv5j1201	487	8	iron	iron	NN
cord-022561-rv5j1201	487	9	availability	availability	NN
cord-022561-rv5j1201	487	10	.	.	.
cord-022561-rv5j1201	488	1	Inflammatory	inflammatory	JJ
cord-022561-rv5j1201	488	2	cytokines	cytokine	NNS
cord-022561-rv5j1201	488	3	are	be	VBP
cord-022561-rv5j1201	488	4	likely	likely	JJ
cord-022561-rv5j1201	488	5	to	to	TO
cord-022561-rv5j1201	488	6	inhibit	inhibit	VB
cord-022561-rv5j1201	488	7	erythropoiesis	erythropoiesis	NN
cord-022561-rv5j1201	488	8	by	by	IN
cord-022561-rv5j1201	488	9	oxidative	oxidative	JJ
cord-022561-rv5j1201	488	10	damage	damage	NN
cord-022561-rv5j1201	488	11	to	to	IN
cord-022561-rv5j1201	488	12	and	and	CC
cord-022561-rv5j1201	488	13	triggering	trigger	VBG
cord-022561-rv5j1201	488	14	apoptosis	apoptosis	NN
cord-022561-rv5j1201	488	15	of	of	IN
cord-022561-rv5j1201	488	16	developing	develop	VBG
cord-022561-rv5j1201	488	17	erythroid	erythroid	NN
cord-022561-rv5j1201	488	18	cells	cell	NNS
cord-022561-rv5j1201	488	19	,	,	,
cord-022561-rv5j1201	488	20	by	by	IN
cord-022561-rv5j1201	488	21	decreasing	decrease	VBG
cord-022561-rv5j1201	488	22	expression	expression	NN
cord-022561-rv5j1201	488	23	of	of	IN
cord-022561-rv5j1201	488	24	Epo	Epo	NNP
cord-022561-rv5j1201	488	25	and	and	CC
cord-022561-rv5j1201	488	26	stem	stem	NN
cord-022561-rv5j1201	488	27	cell	cell	NN
cord-022561-rv5j1201	488	28	factor	factor	NN
cord-022561-rv5j1201	488	29	,	,	,
cord-022561-rv5j1201	488	30	and	and	CC
cord-022561-rv5j1201	488	31	by	by	IN
cord-022561-rv5j1201	488	32	decreasing	decrease	VBG
cord-022561-rv5j1201	488	33	expression	expression	NN
cord-022561-rv5j1201	488	34	of	of	IN
cord-022561-rv5j1201	488	35	Epo	Epo	NNP
cord-022561-rv5j1201	488	36	receptors	receptor	NNS
cord-022561-rv5j1201	488	37	.	.	.
cord-022561-rv5j1201	489	1	In	in	IN
cord-022561-rv5j1201	489	2	addition	addition	NN
cord-022561-rv5j1201	489	3	,	,	,
cord-022561-rv5j1201	489	4	experimentally	experimentally	RB
cord-022561-rv5j1201	489	5	induced	induce	VBN
cord-022561-rv5j1201	489	6	sterile	sterile	JJ
cord-022561-rv5j1201	489	7	inflammation	inflammation	NN
cord-022561-rv5j1201	489	8	in	in	IN
cord-022561-rv5j1201	489	9	cats	cat	NNS
cord-022561-rv5j1201	489	10	resulted	result	VBD
cord-022561-rv5j1201	489	11	in	in	IN
cord-022561-rv5j1201	489	12	shortened	shorten	VBN
cord-022561-rv5j1201	489	13	erythrocyte	erythrocyte	NN
cord-022561-rv5j1201	489	14	survival	survival	NN
cord-022561-rv5j1201	489	15	,	,	,
cord-022561-rv5j1201	489	16	indicating	indicate	VBG
cord-022561-rv5j1201	489	17	that	that	IN
cord-022561-rv5j1201	489	18	anemia	anemia	NN
cord-022561-rv5j1201	489	19	of	of	IN
cord-022561-rv5j1201	489	20	inflammation	inflammation	NN
cord-022561-rv5j1201	489	21	is	be	VBZ
cord-022561-rv5j1201	489	22	likely	likely	RB
cord-022561-rv5j1201	489	23	also	also	RB
cord-022561-rv5j1201	489	24	a	a	DT
cord-022561-rv5j1201	489	25	function	function	NN
cord-022561-rv5j1201	489	26	of	of	IN
cord-022561-rv5j1201	489	27	increased	increase	VBN
cord-022561-rv5j1201	489	28	erythrocyte	erythrocyte	NN
cord-022561-rv5j1201	489	29	destruction	destruction	NN
cord-022561-rv5j1201	489	30	.	.	.
cord-022561-rv5j1201	490	1	Other	other	JJ
cord-022561-rv5j1201	490	2	causes	cause	NNS
cord-022561-rv5j1201	490	3	of	of	IN
cord-022561-rv5j1201	490	4	decreased	decrease	VBN
cord-022561-rv5j1201	490	5	erythropoiesis	erythropoiesis	NN
cord-022561-rv5j1201	490	6	are	be	VBP
cord-022561-rv5j1201	490	7	listed	list	VBN
cord-022561-rv5j1201	490	8	in	in	IN
cord-022561-rv5j1201	490	9	Table	Table	NNP
cord-022561-rv5j1201	490	10	13	13	CD
cord-022561-rv5j1201	490	11	-2	-2	CD
cord-022561-rv5j1201	490	12	.	.	.
cord-022561-rv5j1201	491	1	Specific	specific	JJ
cord-022561-rv5j1201	491	2	examples	example	NNS
cord-022561-rv5j1201	491	3	of	of	IN
cord-022561-rv5j1201	491	4	diseases	disease	NNS
cord-022561-rv5j1201	491	5	causing	cause	VBG
cord-022561-rv5j1201	491	6	nonregenerative	nonregenerative	JJ
cord-022561-rv5j1201	491	7	anemia	anemia	NN
cord-022561-rv5j1201	491	8	by	by	IN
cord-022561-rv5j1201	491	9	these	these	DT
cord-022561-rv5j1201	491	10	mechanisms	mechanism	NNS
cord-022561-rv5j1201	491	11	are	be	VBP
cord-022561-rv5j1201	491	12	discussed	discuss	VBN
cord-022561-rv5j1201	491	13	later	later	RB
cord-022561-rv5j1201	491	14	in	in	IN
cord-022561-rv5j1201	491	15	this	this	DT
cord-022561-rv5j1201	491	16	chapter	chapter	NN
cord-022561-rv5j1201	491	17	.	.	.
cord-022561-rv5j1201	492	1	Neutropenia	neutropenia	NN
cord-022561-rv5j1201	492	2	.	.	.
cord-022561-rv5j1201	493	1	Neutropenia	neutropenia	NN
cord-022561-rv5j1201	493	2	refers	refer	VBZ
cord-022561-rv5j1201	493	3	to	to	IN
cord-022561-rv5j1201	493	4	a	a	DT
cord-022561-rv5j1201	493	5	decrease	decrease	NN
cord-022561-rv5j1201	493	6	in	in	IN
cord-022561-rv5j1201	493	7	the	the	DT
cord-022561-rv5j1201	493	8	concentration	concentration	NN
cord-022561-rv5j1201	493	9	of	of	IN
cord-022561-rv5j1201	493	10	neutrophils	neutrophil	NNS
cord-022561-rv5j1201	493	11	in	in	IN
cord-022561-rv5j1201	493	12	circulating	circulate	VBG
cord-022561-rv5j1201	493	13	blood	blood	NN
cord-022561-rv5j1201	493	14	.	.	.
cord-022561-rv5j1201	494	1	Neutropenia	neutropenia	NN
cord-022561-rv5j1201	494	2	may	may	MD
cord-022561-rv5j1201	494	3	be	be	VB
cord-022561-rv5j1201	494	4	caused	cause	VBN
cord-022561-rv5j1201	494	5	by	by	IN
cord-022561-rv5j1201	494	6	decreased	decreased	JJ
cord-022561-rv5j1201	494	7	production	production	NN
cord-022561-rv5j1201	494	8	,	,	,
cord-022561-rv5j1201	494	9	increased	increase	VBN
cord-022561-rv5j1201	494	10	destruction	destruction	NN
cord-022561-rv5j1201	494	11	,	,	,
cord-022561-rv5j1201	494	12	altered	alter	VBN
cord-022561-rv5j1201	494	13	distribution	distribution	NN
cord-022561-rv5j1201	494	14	,	,	,
cord-022561-rv5j1201	494	15	or	or	CC
cord-022561-rv5j1201	494	16	a	a	DT
cord-022561-rv5j1201	494	17	demand	demand	NN
cord-022561-rv5j1201	494	18	for	for	IN
cord-022561-rv5j1201	494	19	neutrophils	neutrophil	NNS
cord-022561-rv5j1201	494	20	in	in	IN
cord-022561-rv5j1201	494	21	tissues	tissue	NNS
cord-022561-rv5j1201	494	22	that	that	WDT
cord-022561-rv5j1201	494	23	exceeds	exceed	VBZ
cord-022561-rv5j1201	494	24	the	the	DT
cord-022561-rv5j1201	494	25	rate	rate	NN
cord-022561-rv5j1201	494	26	of	of	IN
cord-022561-rv5j1201	494	27	granulopoiesis	granulopoiesis	NN
cord-022561-rv5j1201	494	28	.	.	.
cord-022561-rv5j1201	495	1	Decreased	decrease	VBN
cord-022561-rv5j1201	495	2	production	production	NN
cord-022561-rv5j1201	495	3	is	be	VBZ
cord-022561-rv5j1201	495	4	evident	evident	JJ
cord-022561-rv5j1201	495	5	on	on	IN
cord-022561-rv5j1201	495	6	bone	bone	NN
cord-022561-rv5j1201	495	7	marrow	marrow	NN
cord-022561-rv5j1201	495	8	examination	examination	NN
cord-022561-rv5j1201	495	9	as	as	IN
cord-022561-rv5j1201	495	10	granulocytic	granulocytic	JJ
cord-022561-rv5j1201	495	11	hypoplasia	hypoplasia	NN
cord-022561-rv5j1201	495	12	.	.	.
cord-022561-rv5j1201	496	1	This	this	DT
cord-022561-rv5j1201	496	2	usually	usually	RB
cord-022561-rv5j1201	496	3	results	result	VBZ
cord-022561-rv5j1201	496	4	from	from	IN
cord-022561-rv5j1201	496	5	an	an	DT
cord-022561-rv5j1201	496	6	insult	insult	NN
cord-022561-rv5j1201	496	7	that	that	WDT
cord-022561-rv5j1201	496	8	affects	affect	VBZ
cord-022561-rv5j1201	496	9	multiple	multiple	JJ
cord-022561-rv5j1201	496	10	hematopoietic	hematopoietic	JJ
cord-022561-rv5j1201	496	11	lineages	lineage	NNS
cord-022561-rv5j1201	496	12	,	,	,
cord-022561-rv5j1201	496	13	such	such	JJ
cord-022561-rv5j1201	496	14	as	as	IN
cord-022561-rv5j1201	496	15	chemical	chemical	JJ
cord-022561-rv5j1201	496	16	insult	insult	NN
cord-022561-rv5j1201	496	17	,	,	,
cord-022561-rv5j1201	496	18	radiation	radiation	NN
cord-022561-rv5j1201	496	19	,	,	,
cord-022561-rv5j1201	496	20	neoplasia	neoplasia	NN
cord-022561-rv5j1201	496	21	,	,	,
cord-022561-rv5j1201	496	22	infection	infection	NN
cord-022561-rv5j1201	496	23	,	,	,
cord-022561-rv5j1201	496	24	or	or	CC
cord-022561-rv5j1201	496	25	fibrosis	fibrosis	NN
cord-022561-rv5j1201	496	26	,	,	,
cord-022561-rv5j1201	496	27	but	but	CC
cord-022561-rv5j1201	496	28	may	may	MD
cord-022561-rv5j1201	496	29	also	also	RB
cord-022561-rv5j1201	496	30	be	be	VB
cord-022561-rv5j1201	496	31	caused	cause	VBN
cord-022561-rv5j1201	496	32	by	by	IN
cord-022561-rv5j1201	496	33	a	a	DT
cord-022561-rv5j1201	496	34	process	process	NN
cord-022561-rv5j1201	496	35	that	that	WDT
cord-022561-rv5j1201	496	36	preferentially	preferentially	RB
cord-022561-rv5j1201	496	37	targets	target	VBZ
cord-022561-rv5j1201	496	38	granulopoiesis	granulopoiesis	NN
cord-022561-rv5j1201	496	39	.	.	.
cord-022561-rv5j1201	497	1	In	in	IN
cord-022561-rv5j1201	497	2	marked	marked	JJ
cord-022561-rv5j1201	497	3	contrast	contrast	NN
cord-022561-rv5j1201	497	4	to	to	IN
cord-022561-rv5j1201	497	5	erythrocytes	erythrocyte	NNS
cord-022561-rv5j1201	497	6	,	,	,
cord-022561-rv5j1201	497	7	neutrophils	neutrophil	NNS
cord-022561-rv5j1201	497	8	have	have	VBP
cord-022561-rv5j1201	497	9	a	a	DT
cord-022561-rv5j1201	497	10	very	very	RB
cord-022561-rv5j1201	497	11	short	short	JJ
cord-022561-rv5j1201	497	12	life	life	NN
cord-022561-rv5j1201	497	13	span	span	NN
cord-022561-rv5j1201	497	14	in	in	IN
cord-022561-rv5j1201	497	15	circulation	circulation	NN
cord-022561-rv5j1201	497	16	.	.	.
cord-022561-rv5j1201	498	1	Once	once	RB
cord-022561-rv5j1201	498	2	released	release	VBN
cord-022561-rv5j1201	498	3	from	from	IN
cord-022561-rv5j1201	498	4	the	the	DT
cord-022561-rv5j1201	498	5	bone	bone	NN
cord-022561-rv5j1201	498	6	marrow	marrow	NN
cord-022561-rv5j1201	498	7	,	,	,
cord-022561-rv5j1201	498	8	a	a	DT
cord-022561-rv5j1201	498	9	neutrophil	neutrophil	NN
cord-022561-rv5j1201	498	10	is	be	VBZ
cord-022561-rv5j1201	498	11	in	in	IN
cord-022561-rv5j1201	498	12	the	the	DT
cord-022561-rv5j1201	498	13	bloodstream	bloodstream	NN
cord-022561-rv5j1201	498	14	only	only	RB
cord-022561-rv5j1201	498	15	for	for	IN
cord-022561-rv5j1201	498	16	hours	hour	NNS
cord-022561-rv5j1201	498	17	before	before	IN
cord-022561-rv5j1201	498	18	migrating	migrate	VBG
cord-022561-rv5j1201	498	19	into	into	IN
cord-022561-rv5j1201	498	20	the	the	DT
cord-022561-rv5j1201	498	21	tissues	tissue	NNS
cord-022561-rv5j1201	498	22	.	.	.
cord-022561-rv5j1201	499	1	When	when	WRB
cord-022561-rv5j1201	499	2	neutrophil	neutrophil	NN
cord-022561-rv5j1201	499	3	production	production	NN
cord-022561-rv5j1201	499	4	ceases	cease	VBZ
cord-022561-rv5j1201	499	5	,	,	,
cord-022561-rv5j1201	499	6	a	a	DT
cord-022561-rv5j1201	499	7	reserve	reserve	NN
cord-022561-rv5j1201	499	8	of	of	IN
cord-022561-rv5j1201	499	9	mature	mature	JJ
cord-022561-rv5j1201	499	10	neutrophils	neutrophil	NNS
cord-022561-rv5j1201	499	11	in	in	IN
cord-022561-rv5j1201	499	12	the	the	DT
cord-022561-rv5j1201	499	13	bone	bone	NN
cord-022561-rv5j1201	499	14	marrow	marrow	NN
cord-022561-rv5j1201	499	15	storage	storage	NN
cord-022561-rv5j1201	499	16	pool	pool	NN
cord-022561-rv5j1201	499	17	may	may	MD
cord-022561-rv5j1201	499	18	be	be	VB
cord-022561-rv5j1201	499	19	adequate	adequate	JJ
cord-022561-rv5j1201	499	20	to	to	TO
cord-022561-rv5j1201	499	21	maintain	maintain	VB
cord-022561-rv5j1201	499	22	normal	normal	JJ
cord-022561-rv5j1201	499	23	numbers	number	NNS
cord-022561-rv5j1201	499	24	of	of	IN
cord-022561-rv5j1201	499	25	circulating	circulate	VBG
cord-022561-rv5j1201	499	26	neutrophils	neutrophil	NNS
cord-022561-rv5j1201	499	27	for	for	IN
cord-022561-rv5j1201	499	28	a	a	DT
cord-022561-rv5j1201	499	29	few	few	JJ
cord-022561-rv5j1201	499	30	days	day	NNS
cord-022561-rv5j1201	499	31	;	;	:
cord-022561-rv5j1201	499	32	however	however	RB
cord-022561-rv5j1201	499	33	,	,	,
cord-022561-rv5j1201	499	34	after	after	IN
cord-022561-rv5j1201	499	35	the	the	DT
cord-022561-rv5j1201	499	36	bone	bone	NN
cord-022561-rv5j1201	499	37	marrow	marrow	NN
cord-022561-rv5j1201	499	38	storage	storage	NN
cord-022561-rv5j1201	499	39	pool	pool	NN
cord-022561-rv5j1201	499	40	is	be	VBZ
cord-022561-rv5j1201	499	41	depleted	deplete	VBN
cord-022561-rv5j1201	499	42	,	,	,
cord-022561-rv5j1201	499	43	neutropenia	neutropenia	MD
cord-022561-rv5j1201	499	44	rapidly	rapidly	RB
cord-022561-rv5j1201	499	45	ensues	ensue	VBZ
cord-022561-rv5j1201	499	46	.	.	.
cord-022561-rv5j1201	500	1	Immune	immune	NN
cord-022561-rv5j1201	500	2	-	-	HYPH
cord-022561-rv5j1201	500	3	mediated	mediate	VBN
cord-022561-rv5j1201	500	4	neutropenia	neutropenia	NN
cord-022561-rv5j1201	500	5	is	be	VBZ
cord-022561-rv5j1201	500	6	a	a	DT
cord-022561-rv5j1201	500	7	rare	rare	JJ
cord-022561-rv5j1201	500	8	but	but	CC
cord-022561-rv5j1201	500	9	recognized	recognize	VBN
cord-022561-rv5j1201	500	10	condition	condition	NN
cord-022561-rv5j1201	500	11	in	in	IN
cord-022561-rv5j1201	500	12	domestic	domestic	JJ
cord-022561-rv5j1201	500	13	animals	animal	NNS
cord-022561-rv5j1201	500	14	.	.	.
cord-022561-rv5j1201	501	1	Bone	bone	NN
cord-022561-rv5j1201	501	2	marrow	marrow	NN
cord-022561-rv5j1201	501	3	findings	finding	NNS
cord-022561-rv5j1201	501	4	range	range	VBP
cord-022561-rv5j1201	501	5	from	from	IN
cord-022561-rv5j1201	501	6	granulocytic	granulocytic	JJ
cord-022561-rv5j1201	501	7	hypoplasia	hypoplasia	NN
cord-022561-rv5j1201	501	8	to	to	IN
cord-022561-rv5j1201	501	9	hyperplasia	hyperplasia	NN
cord-022561-rv5j1201	501	10	,	,	,
cord-022561-rv5j1201	501	11	depending	depend	VBG
cord-022561-rv5j1201	501	12	on	on	IN
cord-022561-rv5j1201	501	13	where	where	WRB
cord-022561-rv5j1201	501	14	the	the	DT
cord-022561-rv5j1201	501	15	cells	cell	NNS
cord-022561-rv5j1201	501	16	under	under	IN
cord-022561-rv5j1201	501	17	immune	immune	JJ
cord-022561-rv5j1201	501	18	attack	attack	NN
cord-022561-rv5j1201	501	19	are	be	VBP
cord-022561-rv5j1201	501	20	in	in	IN
cord-022561-rv5j1201	501	21	their	-PRON-	PRP$
cord-022561-rv5j1201	501	22	differentiation	differentiation	NN
cord-022561-rv5j1201	501	23	programs	program	NNS
cord-022561-rv5j1201	501	24	.	.	.
cord-022561-rv5j1201	502	1	Neutropenia	neutropenia	NN
cord-022561-rv5j1201	502	2	with	with	IN
cord-022561-rv5j1201	502	3	no	no	DT
cord-022561-rv5j1201	502	4	evidence	evidence	NN
cord-022561-rv5j1201	502	5	of	of	IN
cord-022561-rv5j1201	502	6	decreased	decreased	JJ
cord-022561-rv5j1201	502	7	production	production	NN
cord-022561-rv5j1201	502	8	and	and	CC
cord-022561-rv5j1201	502	9	in	in	IN
cord-022561-rv5j1201	502	10	which	which	WDT
cord-022561-rv5j1201	502	11	other	other	JJ
cord-022561-rv5j1201	502	12	causes	cause	NNS
cord-022561-rv5j1201	502	13	of	of	IN
cord-022561-rv5j1201	502	14	neutropenia	neutropenia	NN
cord-022561-rv5j1201	502	15	have	have	VBP
cord-022561-rv5j1201	502	16	been	be	VBN
cord-022561-rv5j1201	502	17	excluded	exclude	VBN
cord-022561-rv5j1201	502	18	may	may	MD
cord-022561-rv5j1201	502	19	be	be	VB
cord-022561-rv5j1201	502	20	a	a	DT
cord-022561-rv5j1201	502	21	result	result	NN
cord-022561-rv5j1201	502	22	of	of	IN
cord-022561-rv5j1201	502	23	destruction	destruction	NN
cord-022561-rv5j1201	502	24	of	of	IN
cord-022561-rv5j1201	502	25	neutrophils	neutrophil	NNS
cord-022561-rv5j1201	502	26	before	before	IN
cord-022561-rv5j1201	502	27	they	-PRON-	PRP
cord-022561-rv5j1201	502	28	leave	leave	VBP
cord-022561-rv5j1201	502	29	the	the	DT
cord-022561-rv5j1201	502	30	bone	bone	NN
cord-022561-rv5j1201	502	31	marrow	marrow	NN
cord-022561-rv5j1201	502	32	,	,	,
cord-022561-rv5j1201	502	33	a	a	DT
cord-022561-rv5j1201	502	34	condition	condition	NN
cord-022561-rv5j1201	502	35	known	know	VBN
cord-022561-rv5j1201	502	36	as	as	IN
cord-022561-rv5j1201	502	37	ineffective	ineffective	JJ
cord-022561-rv5j1201	502	38	granulopoiesis	granulopoiesis	NN
cord-022561-rv5j1201	502	39	.	.	.
cord-022561-rv5j1201	503	1	Like	like	IN
cord-022561-rv5j1201	503	2	other	other	JJ
cord-022561-rv5j1201	503	3	forms	form	NNS
cord-022561-rv5j1201	503	4	of	of	IN
cord-022561-rv5j1201	503	5	ineffective	ineffective	JJ
cord-022561-rv5j1201	503	6	hematopoiesis	hematopoiesis	NN
cord-022561-rv5j1201	503	7	,	,	,
cord-022561-rv5j1201	503	8	this	this	DT
cord-022561-rv5j1201	503	9	condition	condition	NN
cord-022561-rv5j1201	503	10	is	be	VBZ
cord-022561-rv5j1201	503	11	often	often	RB
cord-022561-rv5j1201	503	12	presumed	presume	VBN
cord-022561-rv5j1201	503	13	to	to	TO
cord-022561-rv5j1201	503	14	be	be	VB
cord-022561-rv5j1201	503	15	immune	immune	JJ
cord-022561-rv5j1201	503	16	mediated	mediate	VBN
cord-022561-rv5j1201	503	17	;	;	:
cord-022561-rv5j1201	503	18	in	in	IN
cord-022561-rv5j1201	503	19	cats	cat	NNS
cord-022561-rv5j1201	503	20	this	this	DT
cord-022561-rv5j1201	503	21	condition	condition	NN
cord-022561-rv5j1201	503	22	may	may	MD
cord-022561-rv5j1201	503	23	occur	occur	VB
cord-022561-rv5j1201	503	24	as	as	IN
cord-022561-rv5j1201	503	25	a	a	DT
cord-022561-rv5j1201	503	26	result	result	NN
cord-022561-rv5j1201	503	27	of	of	IN
cord-022561-rv5j1201	503	28	infection	infection	NN
cord-022561-rv5j1201	503	29	of	of	IN
cord-022561-rv5j1201	503	30	hematopoietic	hematopoietic	JJ
cord-022561-rv5j1201	503	31	cells	cell	NNS
cord-022561-rv5j1201	503	32	with	with	IN
cord-022561-rv5j1201	503	33	FeLV	FeLV	NNP
cord-022561-rv5j1201	503	34	.	.	.
cord-022561-rv5j1201	504	1	As	as	IN
cord-022561-rv5j1201	504	2	presented	present	VBN
cord-022561-rv5j1201	504	3	in	in	IN
cord-022561-rv5j1201	504	4	the	the	DT
cord-022561-rv5j1201	504	5	earlier	early	JJR
cord-022561-rv5j1201	504	6	section	section	NN
cord-022561-rv5j1201	504	7	on	on	IN
cord-022561-rv5j1201	504	8	Granulopoiesis	Granulopoiesis	NNP
cord-022561-rv5j1201	504	9	and	and	CC
cord-022561-rv5j1201	504	10	Monocytopoiesis	Monocytopoiesis	NNP
cord-022561-rv5j1201	504	11	(	(	-LRB-
cord-022561-rv5j1201	504	12	Myelopoiesis	Myelopoiesis	NNP
cord-022561-rv5j1201	504	13	)	)	-RRB-
cord-022561-rv5j1201	504	14	,	,	,
cord-022561-rv5j1201	504	15	neutrophils	neutrophil	NNS
cord-022561-rv5j1201	504	16	within	within	IN
cord-022561-rv5j1201	504	17	the	the	DT
cord-022561-rv5j1201	504	18	blood	blood	NN
cord-022561-rv5j1201	504	19	vasculature	vasculature	NN
cord-022561-rv5j1201	504	20	are	be	VBP
cord-022561-rv5j1201	504	21	in	in	IN
cord-022561-rv5j1201	504	22	two	two	CD
cord-022561-rv5j1201	504	23	compartments	compartment	NNS
cord-022561-rv5j1201	504	24	:	:	:
cord-022561-rv5j1201	504	25	a	a	DT
cord-022561-rv5j1201	504	26	circulating	circulate	VBG
cord-022561-rv5j1201	504	27	pool	pool	NN
cord-022561-rv5j1201	504	28	,	,	,
cord-022561-rv5j1201	504	29	consisting	consist	VBG
cord-022561-rv5j1201	504	30	of	of	IN
cord-022561-rv5j1201	504	31	those	those	DT
cord-022561-rv5j1201	504	32	cells	cell	NNS
cord-022561-rv5j1201	504	33	flowing	flow	VBG
cord-022561-rv5j1201	504	34	freely	freely	RB
cord-022561-rv5j1201	504	35	in	in	IN
cord-022561-rv5j1201	504	36	the	the	DT
cord-022561-rv5j1201	504	37	blood	blood	NN
cord-022561-rv5j1201	504	38	,	,	,
cord-022561-rv5j1201	504	39	and	and	CC
cord-022561-rv5j1201	504	40	a	a	DT
cord-022561-rv5j1201	504	41	marginating	marginating	NN
cord-022561-rv5j1201	504	42	pool	pool	NN
cord-022561-rv5j1201	504	43	,	,	,
cord-022561-rv5j1201	504	44	consisting	consist	VBG
cord-022561-rv5j1201	504	45	of	of	IN
cord-022561-rv5j1201	504	46	those	those	DT
cord-022561-rv5j1201	504	47	cells	cell	NNS
cord-022561-rv5j1201	504	48	transiently	transiently	RB
cord-022561-rv5j1201	504	49	interacting	interact	VBG
cord-022561-rv5j1201	504	50	with	with	IN
cord-022561-rv5j1201	504	51	the	the	DT
cord-022561-rv5j1201	504	52	endothelial	endothelial	JJ
cord-022561-rv5j1201	504	53	surface	surface	NN
cord-022561-rv5j1201	504	54	.	.	.
cord-022561-rv5j1201	505	1	(	(	-LRB-
cord-022561-rv5j1201	505	2	In	in	IN
cord-022561-rv5j1201	505	3	reality	reality	NN
cord-022561-rv5j1201	505	4	,	,	,
cord-022561-rv5j1201	505	5	neutrophils	neutrophil	NNS
cord-022561-rv5j1201	505	6	are	be	VBP
cord-022561-rv5j1201	505	7	constantly	constantly	RB
cord-022561-rv5j1201	505	8	shifting	shift	VBG
cord-022561-rv5j1201	505	9	between	between	IN
cord-022561-rv5j1201	505	10	these	these	DT
cord-022561-rv5j1201	505	11	two	two	CD
cord-022561-rv5j1201	505	12	pools	pool	NNS
cord-022561-rv5j1201	505	13	,	,	,
cord-022561-rv5j1201	505	14	but	but	CC
cord-022561-rv5j1201	505	15	the	the	DT
cord-022561-rv5j1201	505	16	proportion	proportion	NN
cord-022561-rv5j1201	505	17	of	of	IN
cord-022561-rv5j1201	505	18	cells	cell	NNS
cord-022561-rv5j1201	505	19	in	in	IN
cord-022561-rv5j1201	505	20	either	either	DT
cord-022561-rv5j1201	505	21	pool	pool	NN
cord-022561-rv5j1201	505	22	normally	normally	RB
cord-022561-rv5j1201	505	23	remains	remain	VBZ
cord-022561-rv5j1201	505	24	fairly	fairly	RB
cord-022561-rv5j1201	505	25	Schistocytes	Schistocytes	NNPS
cord-022561-rv5j1201	505	26	are	be	VBP
cord-022561-rv5j1201	505	27	the	the	DT
cord-022561-rv5j1201	505	28	only	only	JJ
cord-022561-rv5j1201	505	29	red	red	JJ
cord-022561-rv5j1201	505	30	blood	blood	NN
cord-022561-rv5j1201	505	31	cell	cell	NN
cord-022561-rv5j1201	505	32	morphologic	morphologic	JJ
cord-022561-rv5j1201	505	33	abnormality	abnormality	NN
cord-022561-rv5j1201	505	34	specific	specific	JJ
cord-022561-rv5j1201	505	35	for	for	IN
cord-022561-rv5j1201	505	36	mechanical	mechanical	JJ
cord-022561-rv5j1201	505	37	fragmentation	fragmentation	NN
cord-022561-rv5j1201	505	38	because	because	IN
cord-022561-rv5j1201	505	39	all	all	DT
cord-022561-rv5j1201	505	40	other	other	JJ
cord-022561-rv5j1201	505	41	morphologic	morphologic	JJ
cord-022561-rv5j1201	505	42	abnormalities	abnormality	NNS
cord-022561-rv5j1201	505	43	can	can	MD
cord-022561-rv5j1201	505	44	be	be	VB
cord-022561-rv5j1201	505	45	seen	see	VBN
cord-022561-rv5j1201	505	46	with	with	IN
cord-022561-rv5j1201	505	47	other	other	JJ
cord-022561-rv5j1201	505	48	disease	disease	NN
cord-022561-rv5j1201	505	49	processes	process	NNS
cord-022561-rv5j1201	505	50	.	.	.
cord-022561-rv5j1201	506	1	For	for	IN
cord-022561-rv5j1201	506	2	example	example	NN
cord-022561-rv5j1201	506	3	,	,	,
cord-022561-rv5j1201	506	4	ghost	ghost	NN
cord-022561-rv5j1201	506	5	cells	cell	NNS
cord-022561-rv5j1201	506	6	may	may	MD
cord-022561-rv5j1201	506	7	be	be	VB
cord-022561-rv5j1201	506	8	observed	observe	VBN
cord-022561-rv5j1201	506	9	with	with	IN
cord-022561-rv5j1201	506	10	other	other	JJ
cord-022561-rv5j1201	506	11	types	type	NNS
cord-022561-rv5j1201	506	12	of	of	IN
cord-022561-rv5j1201	506	13	hemolysis	hemolysis	NN
cord-022561-rv5j1201	506	14	.	.	.
cord-022561-rv5j1201	507	1	Nonregenerative	nonregenerative	JJ
cord-022561-rv5j1201	507	2	anemia	anemia	NN
cord-022561-rv5j1201	507	3	is	be	VBZ
cord-022561-rv5j1201	507	4	characterized	characterize	VBN
cord-022561-rv5j1201	507	5	by	by	IN
cord-022561-rv5j1201	507	6	a	a	DT
cord-022561-rv5j1201	507	7	lack	lack	NN
cord-022561-rv5j1201	507	8	of	of	IN
cord-022561-rv5j1201	507	9	reticulocytosis	reticulocytosis	NN
cord-022561-rv5j1201	507	10	on	on	IN
cord-022561-rv5j1201	507	11	the	the	DT
cord-022561-rv5j1201	507	12	CBC	CBC	NNP
cord-022561-rv5j1201	507	13	;	;	:
cord-022561-rv5j1201	507	14	however	however	RB
cord-022561-rv5j1201	507	15	,	,	,
cord-022561-rv5j1201	507	16	reticulocytosis	reticulocytosis	NNP
cord-022561-rv5j1201	507	17	does	do	VBZ
cord-022561-rv5j1201	507	18	not	not	RB
cord-022561-rv5j1201	507	19	occur	occur	VB
cord-022561-rv5j1201	507	20	in	in	IN
cord-022561-rv5j1201	507	21	horses	horse	NNS
cord-022561-rv5j1201	507	22	even	even	RB
cord-022561-rv5j1201	507	23	in	in	IN
cord-022561-rv5j1201	507	24	the	the	DT
cord-022561-rv5j1201	507	25	context	context	NN
cord-022561-rv5j1201	507	26	of	of	IN
cord-022561-rv5j1201	507	27	regeneration	regeneration	NN
cord-022561-rv5j1201	507	28	.	.	.
cord-022561-rv5j1201	508	1	Most	most	RBS
cord-022561-rv5j1201	508	2	often	often	RB
cord-022561-rv5j1201	508	3	this	this	DT
cord-022561-rv5j1201	508	4	is	be	VBZ
cord-022561-rv5j1201	508	5	a	a	DT
cord-022561-rv5j1201	508	6	result	result	NN
cord-022561-rv5j1201	508	7	of	of	IN
cord-022561-rv5j1201	508	8	decreased	decreased	JJ
cord-022561-rv5j1201	508	9	production	production	NN
cord-022561-rv5j1201	508	10	in	in	IN
cord-022561-rv5j1201	508	11	the	the	DT
cord-022561-rv5j1201	508	12	marrow	marrow	NN
cord-022561-rv5j1201	508	13	(	(	-LRB-
cord-022561-rv5j1201	508	14	i.e.	i.e.	FW
cord-022561-rv5j1201	508	15	,	,	,
cord-022561-rv5j1201	508	16	erythroid	erythroid	NN
cord-022561-rv5j1201	508	17	hypoplasia	hypoplasia	NN
cord-022561-rv5j1201	508	18	)	)	-RRB-
cord-022561-rv5j1201	508	19	.	.	.
cord-022561-rv5j1201	509	1	Erythrocytes	erythrocyte	NNS
cord-022561-rv5j1201	509	2	circulate	circulate	VBP
cord-022561-rv5j1201	509	3	for	for	IN
cord-022561-rv5j1201	509	4	a	a	DT
cord-022561-rv5j1201	509	5	long	long	JJ
cord-022561-rv5j1201	509	6	time	time	NN
cord-022561-rv5j1201	509	7	,	,	,
cord-022561-rv5j1201	509	8	so	so	RB
cord-022561-rv5j1201	509	9	anemias	anemia	NNS
cord-022561-rv5j1201	509	10	caused	cause	VBN
cord-022561-rv5j1201	509	11	by	by	IN
cord-022561-rv5j1201	509	12	decreased	decreased	JJ
cord-022561-rv5j1201	509	13	production	production	NN
cord-022561-rv5j1201	509	14	tend	tend	VBP
cord-022561-rv5j1201	509	15	to	to	TO
cord-022561-rv5j1201	509	16	develop	develop	VB
cord-022561-rv5j1201	509	17	slowly	slowly	RB
cord-022561-rv5j1201	509	18	.	.	.
cord-022561-rv5j1201	510	1	The	the	DT
cord-022561-rv5j1201	510	2	most	most	RBS
cord-022561-rv5j1201	510	3	common	common	JJ
cord-022561-rv5j1201	510	4	form	form	NN
cord-022561-rv5j1201	510	5	of	of	IN
cord-022561-rv5j1201	510	6	nonregenerative	nonregenerative	JJ
cord-022561-rv5j1201	510	7	anemia	anemia	NN
cord-022561-rv5j1201	510	8	is	be	VBZ
cord-022561-rv5j1201	510	9	known	know	VBN
cord-022561-rv5j1201	510	10	as	as	IN
cord-022561-rv5j1201	510	11	anemia	anemia	NN
cord-022561-rv5j1201	510	12	of	of	IN
cord-022561-rv5j1201	510	13	inflammation	inflammation	NN
cord-022561-rv5j1201	510	14	or	or	CC
cord-022561-rv5j1201	510	15	anemia	anemia	NN
cord-022561-rv5j1201	510	16	of	of	IN
cord-022561-rv5j1201	510	17	chronic	chronic	JJ
cord-022561-rv5j1201	510	18	disease	disease	NN
cord-022561-rv5j1201	510	19	.	.	.
cord-022561-rv5j1201	511	1	In	in	IN
cord-022561-rv5j1201	511	2	this	this	DT
cord-022561-rv5j1201	511	3	form	form	NN
cord-022561-rv5j1201	511	4	of	of	IN
cord-022561-rv5j1201	511	5	anemia	anemia	NN
cord-022561-rv5j1201	511	6	,	,	,
cord-022561-rv5j1201	511	7	erythrocytes	erythrocyte	NNS
cord-022561-rv5j1201	511	8	are	be	VBP
cord-022561-rv5j1201	511	9	decreased	decrease	VBN
cord-022561-rv5j1201	511	10	in	in	IN
cord-022561-rv5j1201	511	11	number	number	NN
cord-022561-rv5j1201	511	12	but	but	CC
cord-022561-rv5j1201	511	13	are	be	VBP
cord-022561-rv5j1201	511	14	typically	typically	RB
cord-022561-rv5j1201	511	15	normal	normal	JJ
cord-022561-rv5j1201	511	16	in	in	IN
cord-022561-rv5j1201	511	17	size	size	NN
cord-022561-rv5j1201	511	18	and	and	CC
cord-022561-rv5j1201	511	19	hemoglobin	hemoglobin	NN
cord-022561-rv5j1201	511	20	concentration	concentration	NN
cord-022561-rv5j1201	511	21	(	(	-LRB-
cord-022561-rv5j1201	511	22	so	so	RB
cord-022561-rv5j1201	511	23	-	-	HYPH
cord-022561-rv5j1201	511	24	called	call	VBN
cord-022561-rv5j1201	511	25	C	c	NN
cord-022561-rv5j1201	511	26	or	or	CC
cord-022561-rv5j1201	511	27	because	because	IN
cord-022561-rv5j1201	511	28	of	of	IN
cord-022561-rv5j1201	511	29	one	one	CD
cord-022561-rv5j1201	511	30	specifically	specifically	RB
cord-022561-rv5j1201	511	31	depressing	depress	VBG
cord-022561-rv5j1201	511	32	thrombopoiesis	thrombopoiesis	NN
cord-022561-rv5j1201	511	33	.	.	.
cord-022561-rv5j1201	512	1	In	in	IN
cord-022561-rv5j1201	512	2	either	either	DT
cord-022561-rv5j1201	512	3	case	case	NN
cord-022561-rv5j1201	512	4	,	,	,
cord-022561-rv5j1201	512	5	decreased	decrease	VBD
cord-022561-rv5j1201	512	6	thrombopoiesis	thrombopoiesis	NNP
cord-022561-rv5j1201	512	7	is	be	VBZ
cord-022561-rv5j1201	512	8	evident	evident	JJ
cord-022561-rv5j1201	512	9	as	as	IN
cord-022561-rv5j1201	512	10	megakaryocytic	megakaryocytic	JJ
cord-022561-rv5j1201	512	11	hypoplasia	hypoplasia	NN
cord-022561-rv5j1201	512	12	upon	upon	IN
cord-022561-rv5j1201	512	13	bone	bone	NN
cord-022561-rv5j1201	512	14	marrow	marrow	NN
cord-022561-rv5j1201	512	15	examination	examination	NN
cord-022561-rv5j1201	512	16	.	.	.
cord-022561-rv5j1201	513	1	General	general	JJ
cord-022561-rv5j1201	513	2	causes	cause	NNS
cord-022561-rv5j1201	513	3	of	of	IN
cord-022561-rv5j1201	513	4	decreased	decrease	VBN
cord-022561-rv5j1201	513	5	hematopoiesis	hematopoiesis	NN
cord-022561-rv5j1201	513	6	outlined	outline	VBN
cord-022561-rv5j1201	513	7	earlier	early	RBR
cord-022561-rv5j1201	513	8	in	in	IN
cord-022561-rv5j1201	513	9	the	the	DT
cord-022561-rv5j1201	513	10	sections	section	NNS
cord-022561-rv5j1201	513	11	on	on	IN
cord-022561-rv5j1201	513	12	anemia	anemia	NN
cord-022561-rv5j1201	513	13	and	and	CC
cord-022561-rv5j1201	513	14	neutropenia	neutropenia	NN
cord-022561-rv5j1201	513	15	also	also	RB
cord-022561-rv5j1201	513	16	apply	apply	VBP
cord-022561-rv5j1201	513	17	to	to	IN
cord-022561-rv5j1201	513	18	thrombocytopenia	thrombocytopenia	NN
cord-022561-rv5j1201	513	19	.	.	.
cord-022561-rv5j1201	514	1	Increased	increase	VBN
cord-022561-rv5j1201	514	2	platelet	platelet	NN
cord-022561-rv5j1201	514	3	destruction	destruction	NN
cord-022561-rv5j1201	514	4	due	due	IN
cord-022561-rv5j1201	514	5	to	to	IN
cord-022561-rv5j1201	514	6	immune	immune	NN
cord-022561-rv5j1201	514	7	-	-	HYPH
cord-022561-rv5j1201	514	8	mediated	mediate	VBN
cord-022561-rv5j1201	514	9	thrombocytopenia	thrombocytopenia	NN
cord-022561-rv5j1201	514	10	(	(	-LRB-
cord-022561-rv5j1201	514	11	IMTP	IMTP	NNP
cord-022561-rv5j1201	514	12	)	)	-RRB-
cord-022561-rv5j1201	514	13	is	be	VBZ
cord-022561-rv5j1201	514	14	a	a	DT
cord-022561-rv5j1201	514	15	fairly	fairly	RB
cord-022561-rv5j1201	514	16	common	common	JJ
cord-022561-rv5j1201	514	17	disease	disease	NN
cord-022561-rv5j1201	514	18	in	in	IN
cord-022561-rv5j1201	514	19	dogs	dog	NNS
cord-022561-rv5j1201	514	20	and	and	CC
cord-022561-rv5j1201	514	21	may	may	MD
cord-022561-rv5j1201	514	22	also	also	RB
cord-022561-rv5j1201	514	23	occur	occur	VB
cord-022561-rv5j1201	514	24	in	in	IN
cord-022561-rv5j1201	514	25	other	other	JJ
cord-022561-rv5j1201	514	26	species	specie	NNS
cord-022561-rv5j1201	514	27	.	.	.
cord-022561-rv5j1201	515	1	Thrombocytopenia	Thrombocytopenia	NNP
cord-022561-rv5j1201	515	2	with	with	IN
cord-022561-rv5j1201	515	3	immune	immune	NN
cord-022561-rv5j1201	515	4	-	-	HYPH
cord-022561-rv5j1201	515	5	mediated	mediate	VBN
cord-022561-rv5j1201	515	6	thrombocytopenia	thrombocytopenia	NN
cord-022561-rv5j1201	515	7	is	be	VBZ
cord-022561-rv5j1201	515	8	often	often	RB
cord-022561-rv5j1201	515	9	severe	severe	JJ
cord-022561-rv5j1201	515	10	(	(	-LRB-
cord-022561-rv5j1201	515	11	e.g.	e.g.	RB
cord-022561-rv5j1201	515	12	,	,	,
cord-022561-rv5j1201	515	13	<	<	XX
cord-022561-rv5j1201	515	14	10,000	10,000	CD
cord-022561-rv5j1201	515	15	platelets/µL	platelets/µL	NNS
cord-022561-rv5j1201	515	16	)	)	-RRB-
cord-022561-rv5j1201	515	17	,	,	,
cord-022561-rv5j1201	515	18	resulting	result	VBG
cord-022561-rv5j1201	515	19	in	in	IN
cord-022561-rv5j1201	515	20	spontaneous	spontaneous	JJ
cord-022561-rv5j1201	515	21	multisystemic	multisystemic	JJ
cord-022561-rv5j1201	515	22	hemorrhage	hemorrhage	NN
cord-022561-rv5j1201	515	23	.	.	.
cord-022561-rv5j1201	516	1	Increased	increase	VBN
cord-022561-rv5j1201	516	2	use	use	NN
cord-022561-rv5j1201	516	3	of	of	IN
cord-022561-rv5j1201	516	4	platelets	platelet	NNS
cord-022561-rv5j1201	516	5	occurs	occur	VBZ
cord-022561-rv5j1201	516	6	with	with	IN
cord-022561-rv5j1201	516	7	hemorrhage	hemorrhage	NN
cord-022561-rv5j1201	516	8	and	and	CC
cord-022561-rv5j1201	516	9	disseminated	disseminate	VBN
cord-022561-rv5j1201	516	10	intravascular	intravascular	JJ
cord-022561-rv5j1201	516	11	coagulation	coagulation	NN
cord-022561-rv5j1201	516	12	.	.	.
cord-022561-rv5j1201	517	1	Thrombocytopenia	Thrombocytopenia	NNP
cord-022561-rv5j1201	517	2	secondary	secondary	JJ
cord-022561-rv5j1201	517	3	to	to	IN
cord-022561-rv5j1201	517	4	hemorrhage	hemorrhage	NN
cord-022561-rv5j1201	517	5	is	be	VBZ
cord-022561-rv5j1201	517	6	often	often	RB
cord-022561-rv5j1201	517	7	mild	mild	JJ
cord-022561-rv5j1201	517	8	to	to	TO
cord-022561-rv5j1201	517	9	moderate	moderate	JJ
cord-022561-rv5j1201	517	10	,	,	,
cord-022561-rv5j1201	517	11	whereas	whereas	IN
cord-022561-rv5j1201	517	12	disseminated	disseminate	VBN
cord-022561-rv5j1201	517	13	intravascular	intravascular	JJ
cord-022561-rv5j1201	517	14	coagulation	coagulation	NN
cord-022561-rv5j1201	517	15	may	may	MD
cord-022561-rv5j1201	517	16	cause	cause	VB
cord-022561-rv5j1201	517	17	mild	mild	JJ
cord-022561-rv5j1201	517	18	to	to	IN
cord-022561-rv5j1201	517	19	severe	severe	JJ
cord-022561-rv5j1201	517	20	thrombocytopenia	thrombocytopenia	NN
cord-022561-rv5j1201	517	21	,	,	,
cord-022561-rv5j1201	517	22	often	often	RB
cord-022561-rv5j1201	517	23	with	with	IN
cord-022561-rv5j1201	517	24	evidence	evidence	NN
cord-022561-rv5j1201	517	25	of	of	IN
cord-022561-rv5j1201	517	26	mechanical	mechanical	JJ
cord-022561-rv5j1201	517	27	fragmentation	fragmentation	NN
cord-022561-rv5j1201	517	28	hemolysis	hemolysis	NN
cord-022561-rv5j1201	517	29	(	(	-LRB-
cord-022561-rv5j1201	517	30	e.g.	e.g.	RB
cord-022561-rv5j1201	517	31	,	,	,
cord-022561-rv5j1201	517	32	schistocytes	schistocytes	NNP
cord-022561-rv5j1201	517	33	)	)	-RRB-
cord-022561-rv5j1201	517	34	.	.	.
cord-022561-rv5j1201	518	1	Disseminated	disseminate	VBN
cord-022561-rv5j1201	518	2	intravascular	intravascular	JJ
cord-022561-rv5j1201	518	3	coagulation	coagulation	NN
cord-022561-rv5j1201	518	4	is	be	VBZ
cord-022561-rv5j1201	518	5	a	a	DT
cord-022561-rv5j1201	518	6	syndrome	syndrome	NN
cord-022561-rv5j1201	518	7	in	in	IN
cord-022561-rv5j1201	518	8	which	which	WDT
cord-022561-rv5j1201	518	9	hypercoagulability	hypercoagulability	NN
cord-022561-rv5j1201	518	10	leads	lead	VBZ
cord-022561-rv5j1201	518	11	to	to	IN
cord-022561-rv5j1201	518	12	increased	increase	VBN
cord-022561-rv5j1201	518	13	consumption	consumption	NN
cord-022561-rv5j1201	518	14	of	of	IN
cord-022561-rv5j1201	518	15	both	both	DT
cord-022561-rv5j1201	518	16	platelets	platelet	NNS
cord-022561-rv5j1201	518	17	and	and	CC
cord-022561-rv5j1201	518	18	coagulation	coagulation	NN
cord-022561-rv5j1201	518	19	factors	factor	NNS
cord-022561-rv5j1201	518	20	in	in	IN
cord-022561-rv5j1201	518	21	the	the	DT
cord-022561-rv5j1201	518	22	plasma	plasma	NN
cord-022561-rv5j1201	518	23	,	,	,
cord-022561-rv5j1201	518	24	with	with	IN
cord-022561-rv5j1201	518	25	subsequent	subsequent	JJ
cord-022561-rv5j1201	518	26	hypocoagulability	hypocoagulability	NN
cord-022561-rv5j1201	518	27	and	and	CC
cord-022561-rv5j1201	518	28	susceptibility	susceptibility	NN
cord-022561-rv5j1201	518	29	to	to	IN
cord-022561-rv5j1201	518	30	bleeding	bleed	VBG
cord-022561-rv5j1201	518	31	.	.	.
cord-022561-rv5j1201	519	1	Risk	risk	NN
cord-022561-rv5j1201	519	2	factors	factor	NNS
cord-022561-rv5j1201	519	3	for	for	IN
cord-022561-rv5j1201	519	4	developing	develop	VBG
cord-022561-rv5j1201	519	5	disseminated	disseminate	VBN
cord-022561-rv5j1201	519	6	intravascular	intravascular	JJ
cord-022561-rv5j1201	519	7	coagulation	coagulation	NN
cord-022561-rv5j1201	519	8	include	include	VBP
cord-022561-rv5j1201	519	9	severe	severe	JJ
cord-022561-rv5j1201	519	10	inflammation	inflammation	NN
cord-022561-rv5j1201	519	11	,	,	,
cord-022561-rv5j1201	519	12	such	such	JJ
cord-022561-rv5j1201	519	13	as	as	IN
cord-022561-rv5j1201	519	14	sepsis	sepsis	NN
cord-022561-rv5j1201	519	15	or	or	CC
cord-022561-rv5j1201	519	16	pancreatitis	pancreatitis	NN
cord-022561-rv5j1201	519	17	,	,	,
cord-022561-rv5j1201	519	18	neoplasia	neoplasia	NN
cord-022561-rv5j1201	519	19	,	,	,
cord-022561-rv5j1201	519	20	and	and	CC
cord-022561-rv5j1201	519	21	organ	organ	NN
cord-022561-rv5j1201	519	22	failure	failure	NN
cord-022561-rv5j1201	519	23	.	.	.
cord-022561-rv5j1201	520	1	The	the	DT
cord-022561-rv5j1201	520	2	spleen	spleen	NNS
cord-022561-rv5j1201	520	3	normally	normally	RB
cord-022561-rv5j1201	520	4	contains	contain	VBZ
cord-022561-rv5j1201	520	5	a	a	DT
cord-022561-rv5j1201	520	6	significant	significant	JJ
cord-022561-rv5j1201	520	7	proportion	proportion	NN
cord-022561-rv5j1201	520	8	of	of	IN
cord-022561-rv5j1201	520	9	total	total	JJ
cord-022561-rv5j1201	520	10	platelet	platelet	NN
cord-022561-rv5j1201	520	11	mass	mass	NN
cord-022561-rv5j1201	520	12	(	(	-LRB-
cord-022561-rv5j1201	520	13	up	up	IN
cord-022561-rv5j1201	520	14	to	to	IN
cord-022561-rv5j1201	520	15	one	one	CD
cord-022561-rv5j1201	520	16	-	-	HYPH
cord-022561-rv5j1201	520	17	third	third	NN
cord-022561-rv5j1201	520	18	in	in	IN
cord-022561-rv5j1201	520	19	some	some	DT
cord-022561-rv5j1201	520	20	species	specie	NNS
cord-022561-rv5j1201	520	21	)	)	-RRB-
cord-022561-rv5j1201	520	22	,	,	,
cord-022561-rv5j1201	520	23	and	and	CC
cord-022561-rv5j1201	520	24	abnormalities	abnormality	NNS
cord-022561-rv5j1201	520	25	involving	involve	VBG
cord-022561-rv5j1201	520	26	the	the	DT
cord-022561-rv5j1201	520	27	spleen	spleen	NN
cord-022561-rv5j1201	520	28	may	may	MD
cord-022561-rv5j1201	520	29	result	result	VB
cord-022561-rv5j1201	520	30	in	in	IN
cord-022561-rv5j1201	520	31	changes	change	NNS
cord-022561-rv5j1201	520	32	in	in	IN
cord-022561-rv5j1201	520	33	the	the	DT
cord-022561-rv5j1201	520	34	number	number	NN
cord-022561-rv5j1201	520	35	of	of	IN
cord-022561-rv5j1201	520	36	circulating	circulate	VBG
cord-022561-rv5j1201	520	37	platelets	platelet	NNS
cord-022561-rv5j1201	520	38	.	.	.
cord-022561-rv5j1201	521	1	For	for	IN
cord-022561-rv5j1201	521	2	example	example	NN
cord-022561-rv5j1201	521	3	,	,	,
cord-022561-rv5j1201	521	4	splenic	splenic	JJ
cord-022561-rv5j1201	521	5	congestion	congestion	NN
cord-022561-rv5j1201	521	6	may	may	MD
cord-022561-rv5j1201	521	7	result	result	VB
cord-022561-rv5j1201	521	8	in	in	IN
cord-022561-rv5j1201	521	9	platelet	platelet	NN
cord-022561-rv5j1201	521	10	sequestration	sequestration	NN
cord-022561-rv5j1201	521	11	and	and	CC
cord-022561-rv5j1201	521	12	thrombocytopenia	thrombocytopenia	NN
cord-022561-rv5j1201	521	13	,	,	,
cord-022561-rv5j1201	521	14	and	and	CC
cord-022561-rv5j1201	521	15	splenic	splenic	JJ
cord-022561-rv5j1201	521	16	contraction	contraction	NN
cord-022561-rv5j1201	521	17	may	may	MD
cord-022561-rv5j1201	521	18	cause	cause	VB
cord-022561-rv5j1201	521	19	thrombocytosis	thrombocytosis	NNP
cord-022561-rv5j1201	521	20	.	.	.
cord-022561-rv5j1201	522	1	Lymphopenia	Lymphopenia	NNP
cord-022561-rv5j1201	522	2	.	.	.
cord-022561-rv5j1201	523	1	Lymphopenia	Lymphopenia	NNP
cord-022561-rv5j1201	523	2	refers	refer	VBZ
cord-022561-rv5j1201	523	3	to	to	IN
cord-022561-rv5j1201	523	4	a	a	DT
cord-022561-rv5j1201	523	5	decreased	decrease	VBN
cord-022561-rv5j1201	523	6	concentration	concentration	NN
cord-022561-rv5j1201	523	7	of	of	IN
cord-022561-rv5j1201	523	8	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	523	9	in	in	IN
cord-022561-rv5j1201	523	10	blood	blood	NN
cord-022561-rv5j1201	523	11	.	.	.
cord-022561-rv5j1201	524	1	It	-PRON-	PRP
cord-022561-rv5j1201	524	2	is	be	VBZ
cord-022561-rv5j1201	524	3	a	a	DT
cord-022561-rv5j1201	524	4	common	common	JJ
cord-022561-rv5j1201	524	5	hematologic	hematologic	JJ
cord-022561-rv5j1201	524	6	finding	finding	NN
cord-022561-rv5j1201	524	7	in	in	IN
cord-022561-rv5j1201	524	8	sick	sick	JJ
cord-022561-rv5j1201	524	9	animals	animal	NNS
cord-022561-rv5j1201	524	10	.	.	.
cord-022561-rv5j1201	525	1	Usually	usually	RB
cord-022561-rv5j1201	525	2	the	the	DT
cord-022561-rv5j1201	525	3	precise	precise	JJ
cord-022561-rv5j1201	525	4	mechanism	mechanism	NN
cord-022561-rv5j1201	525	5	of	of	IN
cord-022561-rv5j1201	525	6	lymphopenia	lymphopenia	NNP
cord-022561-rv5j1201	525	7	is	be	VBZ
cord-022561-rv5j1201	525	8	not	not	RB
cord-022561-rv5j1201	525	9	clear	clear	JJ
cord-022561-rv5j1201	525	10	but	but	CC
cord-022561-rv5j1201	525	11	is	be	VBZ
cord-022561-rv5j1201	525	12	often	often	RB
cord-022561-rv5j1201	525	13	presumed	presume	VBN
cord-022561-rv5j1201	525	14	secondary	secondary	JJ
cord-022561-rv5j1201	525	15	to	to	IN
cord-022561-rv5j1201	525	16	endogenous	endogenous	JJ
cord-022561-rv5j1201	525	17	glucocorticoid	glucocorticoid	NN
cord-022561-rv5j1201	525	18	excess	excess	NN
cord-022561-rv5j1201	525	19	that	that	WDT
cord-022561-rv5j1201	525	20	occurs	occur	VBZ
cord-022561-rv5j1201	525	21	with	with	IN
cord-022561-rv5j1201	525	22	stress	stress	NN
cord-022561-rv5j1201	525	23	.	.	.
cord-022561-rv5j1201	526	1	Excess	excess	JJ
cord-022561-rv5j1201	526	2	glucocorticoids	glucocorticoid	NNS
cord-022561-rv5j1201	526	3	,	,	,
cord-022561-rv5j1201	526	4	either	either	CC
cord-022561-rv5j1201	526	5	endogenous	endogenous	JJ
cord-022561-rv5j1201	526	6	or	or	CC
cord-022561-rv5j1201	526	7	exogenous	exogenous	JJ
cord-022561-rv5j1201	526	8	,	,	,
cord-022561-rv5j1201	526	9	cause	cause	VB
cord-022561-rv5j1201	526	10	an	an	DT
cord-022561-rv5j1201	526	11	altered	altered	JJ
cord-022561-rv5j1201	526	12	distribution	distribution	NN
cord-022561-rv5j1201	526	13	of	of	IN
cord-022561-rv5j1201	526	14	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	526	15	;	;	:
cord-022561-rv5j1201	526	16	there	there	EX
cord-022561-rv5j1201	526	17	is	be	VBZ
cord-022561-rv5j1201	526	18	increased	increase	VBN
cord-022561-rv5j1201	526	19	trafficking	trafficking	NN
cord-022561-rv5j1201	526	20	of	of	IN
cord-022561-rv5j1201	526	21	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	526	22	from	from	IN
cord-022561-rv5j1201	526	23	blood	blood	NN
cord-022561-rv5j1201	526	24	to	to	IN
cord-022561-rv5j1201	526	25	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	526	26	tissue	tissue	NN
cord-022561-rv5j1201	526	27	,	,	,
cord-022561-rv5j1201	526	28	and	and	CC
cord-022561-rv5j1201	526	29	decreased	decrease	VBD
cord-022561-rv5j1201	526	30	egress	egress	NN
cord-022561-rv5j1201	526	31	of	of	IN
cord-022561-rv5j1201	526	32	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	526	33	from	from	IN
cord-022561-rv5j1201	526	34	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	526	35	tissue	tissue	NN
cord-022561-rv5j1201	526	36	to	to	IN
cord-022561-rv5j1201	526	37	blood	blood	NN
cord-022561-rv5j1201	526	38	.	.	.
cord-022561-rv5j1201	527	1	At	at	IN
cord-022561-rv5j1201	527	2	higher	high	JJR
cord-022561-rv5j1201	527	3	concentrations	concentration	NNS
cord-022561-rv5j1201	527	4	of	of	IN
cord-022561-rv5j1201	527	5	glucocorticoids	glucocorticoid	NNS
cord-022561-rv5j1201	527	6	,	,	,
cord-022561-rv5j1201	527	7	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	527	8	are	be	VBP
cord-022561-rv5j1201	527	9	destroyed	destroy	VBN
cord-022561-rv5j1201	527	10	.	.	.
cord-022561-rv5j1201	528	1	Other	other	JJ
cord-022561-rv5j1201	528	2	causes	cause	NNS
cord-022561-rv5j1201	528	3	of	of	IN
cord-022561-rv5j1201	528	4	lymphotoxicity	lymphotoxicity	NN
cord-022561-rv5j1201	528	5	include	include	VBP
cord-022561-rv5j1201	528	6	chemotherapeutic	chemotherapeutic	JJ
cord-022561-rv5j1201	528	7	agents	agent	NNS
cord-022561-rv5j1201	528	8	,	,	,
cord-022561-rv5j1201	528	9	radiation	radiation	NN
cord-022561-rv5j1201	528	10	therapy	therapy	NN
cord-022561-rv5j1201	528	11	,	,	,
cord-022561-rv5j1201	528	12	and	and	CC
cord-022561-rv5j1201	528	13	some	some	DT
cord-022561-rv5j1201	528	14	infectious	infectious	JJ
cord-022561-rv5j1201	528	15	agents	agent	NNS
cord-022561-rv5j1201	528	16	.	.	.
cord-022561-rv5j1201	529	1	Lymphopenia	Lymphopenia	NNP
cord-022561-rv5j1201	529	2	may	may	MD
cord-022561-rv5j1201	529	3	occur	occur	VB
cord-022561-rv5j1201	529	4	with	with	IN
cord-022561-rv5j1201	529	5	various	various	JJ
cord-022561-rv5j1201	529	6	mechanisms	mechanism	NNS
cord-022561-rv5j1201	529	7	,	,	,
cord-022561-rv5j1201	529	8	including	include	VBG
cord-022561-rv5j1201	529	9	loss	loss	NN
cord-022561-rv5j1201	529	10	of	of	IN
cord-022561-rv5j1201	529	11	lymphocyte	lymphocyte	NN
cord-022561-rv5j1201	529	12	-	-	HYPH
cord-022561-rv5j1201	529	13	rich	rich	JJ
cord-022561-rv5j1201	529	14	lymphatic	lymphatic	NN
cord-022561-rv5j1201	529	15	fluid	fluid	NN
cord-022561-rv5j1201	529	16	(	(	-LRB-
cord-022561-rv5j1201	529	17	e.g.	e.g.	RB
cord-022561-rv5j1201	529	18	,	,	,
cord-022561-rv5j1201	529	19	gastrointestinal	gastrointestinal	JJ
cord-022561-rv5j1201	529	20	disease	disease	NN
cord-022561-rv5j1201	529	21	,	,	,
cord-022561-rv5j1201	529	22	repeated	repeat	VBN
cord-022561-rv5j1201	529	23	drainage	drainage	NN
cord-022561-rv5j1201	529	24	of	of	IN
cord-022561-rv5j1201	529	25	chylous	chylous	JJ
cord-022561-rv5j1201	529	26	effusions	effusion	NNS
cord-022561-rv5j1201	529	27	)	)	-RRB-
cord-022561-rv5j1201	529	28	,	,	,
cord-022561-rv5j1201	529	29	and	and	CC
cord-022561-rv5j1201	529	30	disruption	disruption	NN
cord-022561-rv5j1201	529	31	of	of	IN
cord-022561-rv5j1201	529	32	the	the	DT
cord-022561-rv5j1201	529	33	normal	normal	JJ
cord-022561-rv5j1201	529	34	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	529	35	tissue	tissue	NN
cord-022561-rv5j1201	529	36	architecture	architecture	NN
cord-022561-rv5j1201	529	37	because	because	IN
cord-022561-rv5j1201	529	38	constant	constant	JJ
cord-022561-rv5j1201	529	39	in	in	IN
cord-022561-rv5j1201	529	40	any	any	DT
cord-022561-rv5j1201	529	41	given	give	VBN
cord-022561-rv5j1201	529	42	species	species	NN
cord-022561-rv5j1201	529	43	.	.	.
cord-022561-rv5j1201	529	44	)	)	-RRB-
cord-022561-rv5j1201	530	1	Circulating	circulate	VBG
cord-022561-rv5j1201	530	2	neutrophils	neutrophil	NNS
cord-022561-rv5j1201	530	3	are	be	VBP
cord-022561-rv5j1201	530	4	part	part	NN
cord-022561-rv5j1201	530	5	of	of	IN
cord-022561-rv5j1201	530	6	the	the	DT
cord-022561-rv5j1201	530	7	blood	blood	NN
cord-022561-rv5j1201	530	8	sample	sample	NN
cord-022561-rv5j1201	530	9	collected	collect	VBN
cord-022561-rv5j1201	530	10	during	during	IN
cord-022561-rv5j1201	530	11	routine	routine	JJ
cord-022561-rv5j1201	530	12	venipuncture	venipuncture	NN
cord-022561-rv5j1201	530	13	and	and	CC
cord-022561-rv5j1201	530	14	are	be	VBP
cord-022561-rv5j1201	530	15	thus	thus	RB
cord-022561-rv5j1201	530	16	counted	count	VBN
cord-022561-rv5j1201	530	17	in	in	IN
cord-022561-rv5j1201	530	18	the	the	DT
cord-022561-rv5j1201	530	19	CBC	CBC	NNP
cord-022561-rv5j1201	530	20	,	,	,
cord-022561-rv5j1201	530	21	whereas	whereas	IN
cord-022561-rv5j1201	530	22	marginating	marginate	VBG
cord-022561-rv5j1201	530	23	neutrophils	neutrophil	NNS
cord-022561-rv5j1201	530	24	are	be	VBP
cord-022561-rv5j1201	530	25	not	not	RB
cord-022561-rv5j1201	530	26	.	.	.
cord-022561-rv5j1201	531	1	Pseudoneutropenia	Pseudoneutropenia	NNP
cord-022561-rv5j1201	531	2	refers	refer	VBZ
cord-022561-rv5j1201	531	3	to	to	IN
cord-022561-rv5j1201	531	4	the	the	DT
cord-022561-rv5j1201	531	5	situation	situation	NN
cord-022561-rv5j1201	531	6	in	in	IN
cord-022561-rv5j1201	531	7	which	which	WDT
cord-022561-rv5j1201	531	8	there	there	EX
cord-022561-rv5j1201	531	9	is	be	VBZ
cord-022561-rv5j1201	531	10	an	an	DT
cord-022561-rv5j1201	531	11	increased	increase	VBN
cord-022561-rv5j1201	531	12	proportion	proportion	NN
cord-022561-rv5j1201	531	13	of	of	IN
cord-022561-rv5j1201	531	14	neutrophils	neutrophil	NNS
cord-022561-rv5j1201	531	15	in	in	IN
cord-022561-rv5j1201	531	16	the	the	DT
cord-022561-rv5j1201	531	17	marginating	marginating	NN
cord-022561-rv5j1201	531	18	pool	pool	NN
cord-022561-rv5j1201	531	19	.	.	.
cord-022561-rv5j1201	532	1	This	this	DT
cord-022561-rv5j1201	532	2	may	may	MD
cord-022561-rv5j1201	532	3	occur	occur	VB
cord-022561-rv5j1201	532	4	because	because	IN
cord-022561-rv5j1201	532	5	of	of	IN
cord-022561-rv5j1201	532	6	decreased	decrease	VBN
cord-022561-rv5j1201	532	7	blood	blood	NN
cord-022561-rv5j1201	532	8	flow	flow	NN
cord-022561-rv5j1201	532	9	or	or	CC
cord-022561-rv5j1201	532	10	in	in	IN
cord-022561-rv5j1201	532	11	response	response	NN
cord-022561-rv5j1201	532	12	to	to	IN
cord-022561-rv5j1201	532	13	stimuli	stimulus	NNS
cord-022561-rv5j1201	532	14	,	,	,
cord-022561-rv5j1201	532	15	such	such	JJ
cord-022561-rv5j1201	532	16	as	as	IN
cord-022561-rv5j1201	532	17	endotoxemia	endotoxemia	NN
cord-022561-rv5j1201	532	18	,	,	,
cord-022561-rv5j1201	532	19	that	that	WDT
cord-022561-rv5j1201	532	20	increase	increase	VBP
cord-022561-rv5j1201	532	21	expression	expression	NN
cord-022561-rv5j1201	532	22	of	of	IN
cord-022561-rv5j1201	532	23	molecules	molecule	NNS
cord-022561-rv5j1201	532	24	promoting	promote	VBG
cord-022561-rv5j1201	532	25	interaction	interaction	NN
cord-022561-rv5j1201	532	26	between	between	IN
cord-022561-rv5j1201	532	27	neutrophils	neutrophil	NNS
cord-022561-rv5j1201	532	28	and	and	CC
cord-022561-rv5j1201	532	29	endothelial	endothelial	JJ
cord-022561-rv5j1201	532	30	cells	cell	NNS
cord-022561-rv5j1201	532	31	.	.	.
cord-022561-rv5j1201	533	1	This	this	DT
cord-022561-rv5j1201	533	2	mechanism	mechanism	NN
cord-022561-rv5j1201	533	3	of	of	IN
cord-022561-rv5j1201	533	4	neutropenia	neutropenia	NN
cord-022561-rv5j1201	533	5	is	be	VBZ
cord-022561-rv5j1201	533	6	rarely	rarely	RB
cord-022561-rv5j1201	533	7	observed	observe	VBN
cord-022561-rv5j1201	533	8	in	in	IN
cord-022561-rv5j1201	533	9	clinical	clinical	JJ
cord-022561-rv5j1201	533	10	practice	practice	NN
cord-022561-rv5j1201	533	11	.	.	.
cord-022561-rv5j1201	534	1	Neutropenia	neutropenia	NN
cord-022561-rv5j1201	534	2	may	may	MD
cord-022561-rv5j1201	534	3	also	also	RB
cord-022561-rv5j1201	534	4	result	result	VB
cord-022561-rv5j1201	534	5	from	from	IN
cord-022561-rv5j1201	534	6	increased	increase	VBN
cord-022561-rv5j1201	534	7	demand	demand	NN
cord-022561-rv5j1201	534	8	for	for	IN
cord-022561-rv5j1201	534	9	neutrophils	neutrophil	NNS
cord-022561-rv5j1201	534	10	in	in	IN
cord-022561-rv5j1201	534	11	the	the	DT
cord-022561-rv5j1201	534	12	tissue	tissue	NN
cord-022561-rv5j1201	534	13	.	.	.
cord-022561-rv5j1201	535	1	How	how	WRB
cord-022561-rv5j1201	535	2	rapidly	rapidly	RB
cord-022561-rv5j1201	535	3	such	such	PDT
cord-022561-rv5j1201	535	4	a	a	DT
cord-022561-rv5j1201	535	5	situation	situation	NN
cord-022561-rv5j1201	535	6	develops	develop	VBZ
cord-022561-rv5j1201	535	7	depends	depend	VBZ
cord-022561-rv5j1201	535	8	not	not	RB
cord-022561-rv5j1201	535	9	only	only	RB
cord-022561-rv5j1201	535	10	on	on	IN
cord-022561-rv5j1201	535	11	the	the	DT
cord-022561-rv5j1201	535	12	magnitude	magnitude	NN
cord-022561-rv5j1201	535	13	of	of	IN
cord-022561-rv5j1201	535	14	the	the	DT
cord-022561-rv5j1201	535	15	inflammatory	inflammatory	JJ
cord-022561-rv5j1201	535	16	stimulus	stimulus	NN
cord-022561-rv5j1201	535	17	but	but	CC
cord-022561-rv5j1201	535	18	also	also	RB
cord-022561-rv5j1201	535	19	on	on	IN
cord-022561-rv5j1201	535	20	the	the	DT
cord-022561-rv5j1201	535	21	reserve	reserve	NN
cord-022561-rv5j1201	535	22	of	of	IN
cord-022561-rv5j1201	535	23	postmitotic	postmitotic	JJ
cord-022561-rv5j1201	535	24	neutrophils	neutrophil	NNS
cord-022561-rv5j1201	535	25	in	in	IN
cord-022561-rv5j1201	535	26	the	the	DT
cord-022561-rv5j1201	535	27	bone	bone	NN
cord-022561-rv5j1201	535	28	marrow	marrow	NN
cord-022561-rv5j1201	535	29	.	.	.
cord-022561-rv5j1201	536	1	The	the	DT
cord-022561-rv5j1201	536	2	size	size	NN
cord-022561-rv5j1201	536	3	of	of	IN
cord-022561-rv5j1201	536	4	this	this	DT
cord-022561-rv5j1201	536	5	reserve	reserve	NN
cord-022561-rv5j1201	536	6	,	,	,
cord-022561-rv5j1201	536	7	or	or	CC
cord-022561-rv5j1201	536	8	storage	storage	NN
cord-022561-rv5j1201	536	9	pool	pool	NN
cord-022561-rv5j1201	536	10	,	,	,
cord-022561-rv5j1201	536	11	is	be	VBZ
cord-022561-rv5j1201	536	12	species	species	NN
cord-022561-rv5j1201	536	13	dependent	dependent	JJ
cord-022561-rv5j1201	536	14	.	.	.
cord-022561-rv5j1201	537	1	In	in	IN
cord-022561-rv5j1201	537	2	dogs	dog	NNS
cord-022561-rv5j1201	537	3	this	this	DT
cord-022561-rv5j1201	537	4	pool	pool	NN
cord-022561-rv5j1201	537	5	contains	contain	VBZ
cord-022561-rv5j1201	537	6	the	the	DT
cord-022561-rv5j1201	537	7	equivalent	equivalent	NN
cord-022561-rv5j1201	537	8	of	of	IN
cord-022561-rv5j1201	537	9	5	5	CD
cord-022561-rv5j1201	537	10	days	day	NNS
cord-022561-rv5j1201	537	11	'	'	POS
cord-022561-rv5j1201	537	12	normal	normal	JJ
cord-022561-rv5j1201	537	13	production	production	NN
cord-022561-rv5j1201	537	14	of	of	IN
cord-022561-rv5j1201	537	15	neutrophils	neutrophil	NNS
cord-022561-rv5j1201	537	16	.	.	.
cord-022561-rv5j1201	538	1	Cattle	Cattle	NNS
cord-022561-rv5j1201	538	2	represent	represent	VBP
cord-022561-rv5j1201	538	3	the	the	DT
cord-022561-rv5j1201	538	4	other	other	JJ
cord-022561-rv5j1201	538	5	extreme	extreme	NN
cord-022561-rv5j1201	538	6	in	in	IN
cord-022561-rv5j1201	538	7	that	that	IN
cord-022561-rv5j1201	538	8	they	-PRON-	PRP
cord-022561-rv5j1201	538	9	have	have	VBP
cord-022561-rv5j1201	538	10	a	a	DT
cord-022561-rv5j1201	538	11	small	small	JJ
cord-022561-rv5j1201	538	12	storage	storage	NN
cord-022561-rv5j1201	538	13	pool	pool	NN
cord-022561-rv5j1201	538	14	and	and	CC
cord-022561-rv5j1201	538	15	thus	thus	RB
cord-022561-rv5j1201	538	16	are	be	VBP
cord-022561-rv5j1201	538	17	predisposed	predisposed	JJ
cord-022561-rv5j1201	538	18	to	to	IN
cord-022561-rv5j1201	538	19	becoming	become	VBG
cord-022561-rv5j1201	538	20	neutropenic	neutropenic	JJ
cord-022561-rv5j1201	538	21	during	during	IN
cord-022561-rv5j1201	538	22	times	time	NNS
cord-022561-rv5j1201	538	23	of	of	IN
cord-022561-rv5j1201	538	24	acute	acute	JJ
cord-022561-rv5j1201	538	25	inflammation	inflammation	NN
cord-022561-rv5j1201	538	26	.	.	.
cord-022561-rv5j1201	539	1	Horses	horse	NNS
cord-022561-rv5j1201	539	2	and	and	CC
cord-022561-rv5j1201	539	3	cats	cat	NNS
cord-022561-rv5j1201	539	4	are	be	VBP
cord-022561-rv5j1201	539	5	somewhere	somewhere	RB
cord-022561-rv5j1201	539	6	between	between	IN
cord-022561-rv5j1201	539	7	the	the	DT
cord-022561-rv5j1201	539	8	two	two	CD
cord-022561-rv5j1201	539	9	extremes	extreme	NNS
cord-022561-rv5j1201	539	10	,	,	,
cord-022561-rv5j1201	539	11	closer	close	RBR
cord-022561-rv5j1201	539	12	to	to	IN
cord-022561-rv5j1201	539	13	cattle	cattle	NNS
cord-022561-rv5j1201	539	14	and	and	CC
cord-022561-rv5j1201	539	15	dogs	dog	NNS
cord-022561-rv5j1201	539	16	,	,	,
cord-022561-rv5j1201	539	17	respectively	respectively	RB
cord-022561-rv5j1201	539	18	.	.	.
cord-022561-rv5j1201	540	1	It	-PRON-	PRP
cord-022561-rv5j1201	540	2	stands	stand	VBZ
cord-022561-rv5j1201	540	3	to	to	TO
cord-022561-rv5j1201	540	4	reason	reason	VB
cord-022561-rv5j1201	540	5	that	that	IN
cord-022561-rv5j1201	540	6	the	the	DT
cord-022561-rv5j1201	540	7	clinical	clinical	JJ
cord-022561-rv5j1201	540	8	significance	significance	NN
cord-022561-rv5j1201	540	9	of	of	IN
cord-022561-rv5j1201	540	10	neutropenia	neutropenia	NN
cord-022561-rv5j1201	540	11	because	because	IN
cord-022561-rv5j1201	540	12	of	of	IN
cord-022561-rv5j1201	540	13	a	a	DT
cord-022561-rv5j1201	540	14	supply	supply	NN
cord-022561-rv5j1201	540	15	and	and	CC
cord-022561-rv5j1201	540	16	demand	demand	NN
cord-022561-rv5j1201	540	17	imbalance	imbalance	NN
cord-022561-rv5j1201	540	18	is	be	VBZ
cord-022561-rv5j1201	540	19	also	also	RB
cord-022561-rv5j1201	540	20	species	specie	NNS
cord-022561-rv5j1201	540	21	dependent	dependent	JJ
cord-022561-rv5j1201	540	22	.	.	.
cord-022561-rv5j1201	541	1	In	in	IN
cord-022561-rv5j1201	541	2	dogs	dog	NNS
cord-022561-rv5j1201	541	3	,	,	,
cord-022561-rv5j1201	541	4	neutropenia	neutropenia	NN
cord-022561-rv5j1201	541	5	as	as	IN
cord-022561-rv5j1201	541	6	a	a	DT
cord-022561-rv5j1201	541	7	result	result	NN
cord-022561-rv5j1201	541	8	of	of	IN
cord-022561-rv5j1201	541	9	inflammation	inflammation	NN
cord-022561-rv5j1201	541	10	is	be	VBZ
cord-022561-rv5j1201	541	11	an	an	DT
cord-022561-rv5j1201	541	12	alarming	alarming	JJ
cord-022561-rv5j1201	541	13	finding	finding	NN
cord-022561-rv5j1201	541	14	because	because	IN
cord-022561-rv5j1201	541	15	it	-PRON-	PRP
cord-022561-rv5j1201	541	16	is	be	VBZ
cord-022561-rv5j1201	541	17	evidence	evidence	NN
cord-022561-rv5j1201	541	18	of	of	IN
cord-022561-rv5j1201	541	19	a	a	DT
cord-022561-rv5j1201	541	20	massive	massive	JJ
cord-022561-rv5j1201	541	21	tissue	tissue	NN
cord-022561-rv5j1201	541	22	demand	demand	NN
cord-022561-rv5j1201	541	23	for	for	IN
cord-022561-rv5j1201	541	24	neutrophils	neutrophil	NNS
cord-022561-rv5j1201	541	25	that	that	WDT
cord-022561-rv5j1201	541	26	has	have	VBZ
cord-022561-rv5j1201	541	27	exhausted	exhaust	VBN
cord-022561-rv5j1201	541	28	the	the	DT
cord-022561-rv5j1201	541	29	patient	patient	NN
cord-022561-rv5j1201	541	30	's	's	POS
cord-022561-rv5j1201	541	31	storage	storage	NN
cord-022561-rv5j1201	541	32	pool	pool	NN
cord-022561-rv5j1201	541	33	and	and	CC
cord-022561-rv5j1201	541	34	is	be	VBZ
cord-022561-rv5j1201	541	35	exceeding	exceed	VBG
cord-022561-rv5j1201	541	36	the	the	DT
cord-022561-rv5j1201	541	37	rate	rate	NN
cord-022561-rv5j1201	541	38	of	of	IN
cord-022561-rv5j1201	541	39	granulopoiesis	granulopoiesis	NN
cord-022561-rv5j1201	541	40	in	in	IN
cord-022561-rv5j1201	541	41	the	the	DT
cord-022561-rv5j1201	541	42	bone	bone	NN
cord-022561-rv5j1201	541	43	marrow	marrow	NN
cord-022561-rv5j1201	541	44	.	.	.
cord-022561-rv5j1201	542	1	However	however	RB
cord-022561-rv5j1201	542	2	in	in	IN
cord-022561-rv5j1201	542	3	cows	cow	NNS
cord-022561-rv5j1201	542	4	,	,	,
cord-022561-rv5j1201	542	5	neutropenia	neutropenia	NN
cord-022561-rv5j1201	542	6	is	be	VBZ
cord-022561-rv5j1201	542	7	commonly	commonly	RB
cord-022561-rv5j1201	542	8	noted	note	VBN
cord-022561-rv5j1201	542	9	in	in	IN
cord-022561-rv5j1201	542	10	a	a	DT
cord-022561-rv5j1201	542	11	wide	wide	JJ
cord-022561-rv5j1201	542	12	range	range	NN
cord-022561-rv5j1201	542	13	of	of	IN
cord-022561-rv5j1201	542	14	conditions	condition	NNS
cord-022561-rv5j1201	542	15	involving	involve	VBG
cord-022561-rv5j1201	542	16	acute	acute	JJ
cord-022561-rv5j1201	542	17	inflammation	inflammation	NN
cord-022561-rv5j1201	542	18	and	and	CC
cord-022561-rv5j1201	542	19	does	do	VBZ
cord-022561-rv5j1201	542	20	not	not	RB
cord-022561-rv5j1201	542	21	necessarily	necessarily	RB
cord-022561-rv5j1201	542	22	indicate	indicate	VB
cord-022561-rv5j1201	542	23	an	an	DT
cord-022561-rv5j1201	542	24	overwhelming	overwhelming	JJ
cord-022561-rv5j1201	542	25	demand	demand	NN
cord-022561-rv5j1201	542	26	.	.	.
cord-022561-rv5j1201	543	1	Eosinopenia	Eosinopenia	NNP
cord-022561-rv5j1201	543	2	/	/	SYM
cord-022561-rv5j1201	543	3	Basopenia	Basopenia	NNP
cord-022561-rv5j1201	543	4	.	.	.
cord-022561-rv5j1201	544	1	Eosinopenia	Eosinopenia	NNP
cord-022561-rv5j1201	544	2	and	and	CC
cord-022561-rv5j1201	544	3	basopenia	basopenia	NNS
cord-022561-rv5j1201	544	4	are	be	VBP
cord-022561-rv5j1201	544	5	decreased	decrease	VBN
cord-022561-rv5j1201	544	6	concentrations	concentration	NNS
cord-022561-rv5j1201	544	7	of	of	IN
cord-022561-rv5j1201	544	8	blood	blood	NN
cord-022561-rv5j1201	544	9	eosinophils	eosinophil	NNS
cord-022561-rv5j1201	544	10	and	and	CC
cord-022561-rv5j1201	544	11	basophils	basophil	NNS
cord-022561-rv5j1201	544	12	,	,	,
cord-022561-rv5j1201	544	13	respectively	respectively	RB
cord-022561-rv5j1201	544	14	.	.	.
cord-022561-rv5j1201	545	1	In	in	IN
cord-022561-rv5j1201	545	2	many	many	JJ
cord-022561-rv5j1201	545	3	laboratories	laboratory	NNS
cord-022561-rv5j1201	545	4	,	,	,
cord-022561-rv5j1201	545	5	CBC	CBC	NNP
cord-022561-rv5j1201	545	6	reference	reference	NN
cord-022561-rv5j1201	545	7	values	value	NNS
cord-022561-rv5j1201	545	8	for	for	IN
cord-022561-rv5j1201	545	9	eosinophils	eosinophil	NNS
cord-022561-rv5j1201	545	10	and	and	CC
cord-022561-rv5j1201	545	11	basophils	basophil	NNS
cord-022561-rv5j1201	545	12	are	be	VBP
cord-022561-rv5j1201	545	13	as	as	RB
cord-022561-rv5j1201	545	14	low	low	JJ
cord-022561-rv5j1201	545	15	as	as	IN
cord-022561-rv5j1201	545	16	zero	zero	CD
cord-022561-rv5j1201	545	17	cells	cell	NNS
cord-022561-rv5j1201	545	18	per	per	IN
cord-022561-rv5j1201	545	19	microliter	microliter	NN
cord-022561-rv5j1201	545	20	,	,	,
cord-022561-rv5j1201	545	21	precluding	preclude	VBG
cord-022561-rv5j1201	545	22	detection	detection	NN
cord-022561-rv5j1201	545	23	of	of	IN
cord-022561-rv5j1201	545	24	eosinopenia	eosinopenia	NNP
cord-022561-rv5j1201	545	25	or	or	CC
cord-022561-rv5j1201	545	26	basopenia	basopenia	NNP
cord-022561-rv5j1201	545	27	.	.	.
cord-022561-rv5j1201	546	1	When	when	WRB
cord-022561-rv5j1201	546	2	detectable	detectable	JJ
cord-022561-rv5j1201	546	3	,	,	,
cord-022561-rv5j1201	546	4	eosinopenia	eosinopenia	NNP
cord-022561-rv5j1201	546	5	is	be	VBZ
cord-022561-rv5j1201	546	6	often	often	RB
cord-022561-rv5j1201	546	7	a	a	DT
cord-022561-rv5j1201	546	8	result	result	NN
cord-022561-rv5j1201	546	9	of	of	IN
cord-022561-rv5j1201	546	10	stress	stress	NN
cord-022561-rv5j1201	546	11	(	(	-LRB-
cord-022561-rv5j1201	546	12	i.e.	i.e.	FW
cord-022561-rv5j1201	546	13	,	,	,
cord-022561-rv5j1201	546	14	glucocorticoid	glucocorticoid	NN
cord-022561-rv5j1201	546	15	mediated	mediate	VBN
cord-022561-rv5j1201	546	16	)	)	-RRB-
cord-022561-rv5j1201	546	17	.	.	.
cord-022561-rv5j1201	547	1	Monocytopenia	Monocytopenia	NNP
cord-022561-rv5j1201	547	2	.	.	.
cord-022561-rv5j1201	548	1	Monocytopenia	Monocytopenia	NNP
cord-022561-rv5j1201	548	2	denotes	denote	VBZ
cord-022561-rv5j1201	548	3	a	a	DT
cord-022561-rv5j1201	548	4	decreased	decrease	VBN
cord-022561-rv5j1201	548	5	concentration	concentration	NN
cord-022561-rv5j1201	548	6	of	of	IN
cord-022561-rv5j1201	548	7	monocytes	monocyte	NNS
cord-022561-rv5j1201	548	8	in	in	IN
cord-022561-rv5j1201	548	9	blood	blood	NN
cord-022561-rv5j1201	548	10	;	;	:
cord-022561-rv5j1201	548	11	it	-PRON-	PRP
cord-022561-rv5j1201	548	12	is	be	VBZ
cord-022561-rv5j1201	548	13	of	of	IN
cord-022561-rv5j1201	548	14	little	little	JJ
cord-022561-rv5j1201	548	15	to	to	IN
cord-022561-rv5j1201	548	16	no	no	DT
cord-022561-rv5j1201	548	17	pathologic	pathologic	JJ
cord-022561-rv5j1201	548	18	significance	significance	NN
cord-022561-rv5j1201	548	19	by	by	IN
cord-022561-rv5j1201	548	20	itself	-PRON-	PRP
cord-022561-rv5j1201	548	21	.	.	.
cord-022561-rv5j1201	549	1	Thrombocytopenia	Thrombocytopenia	NNP
cord-022561-rv5j1201	549	2	.	.	.
cord-022561-rv5j1201	550	1	Thrombocytopenia	Thrombocytopenia	NNP
cord-022561-rv5j1201	550	2	refers	refer	VBZ
cord-022561-rv5j1201	550	3	to	to	IN
cord-022561-rv5j1201	550	4	a	a	DT
cord-022561-rv5j1201	550	5	decrease	decrease	NN
cord-022561-rv5j1201	550	6	in	in	IN
cord-022561-rv5j1201	550	7	the	the	DT
cord-022561-rv5j1201	550	8	concentration	concentration	NN
cord-022561-rv5j1201	550	9	of	of	IN
cord-022561-rv5j1201	550	10	circulating	circulate	VBG
cord-022561-rv5j1201	550	11	platelets	platelet	NNS
cord-022561-rv5j1201	550	12	.	.	.
cord-022561-rv5j1201	551	1	Mechanisms	mechanism	NNS
cord-022561-rv5j1201	551	2	of	of	IN
cord-022561-rv5j1201	551	3	thrombocytopenia	thrombocytopenia	NNS
cord-022561-rv5j1201	551	4	include	include	VBP
cord-022561-rv5j1201	551	5	decreased	decrease	VBN
cord-022561-rv5j1201	551	6	production	production	NN
cord-022561-rv5j1201	551	7	,	,	,
cord-022561-rv5j1201	551	8	increased	increase	VBN
cord-022561-rv5j1201	551	9	destruction	destruction	NN
cord-022561-rv5j1201	551	10	,	,	,
cord-022561-rv5j1201	551	11	increased	increase	VBN
cord-022561-rv5j1201	551	12	consumption	consumption	NN
cord-022561-rv5j1201	551	13	,	,	,
cord-022561-rv5j1201	551	14	and	and	CC
cord-022561-rv5j1201	551	15	altered	alter	VBN
cord-022561-rv5j1201	551	16	distribution	distribution	NN
cord-022561-rv5j1201	551	17	.	.	.
cord-022561-rv5j1201	552	1	Decreased	decrease	VBN
cord-022561-rv5j1201	552	2	production	production	NN
cord-022561-rv5j1201	552	3	may	may	MD
cord-022561-rv5j1201	552	4	occur	occur	VB
cord-022561-rv5j1201	552	5	because	because	IN
cord-022561-rv5j1201	552	6	of	of	IN
cord-022561-rv5j1201	552	7	a	a	DT
cord-022561-rv5j1201	552	8	condition	condition	NN
cord-022561-rv5j1201	552	9	affecting	affect	VBG
cord-022561-rv5j1201	552	10	cells	cell	NNS
cord-022561-rv5j1201	552	11	of	of	IN
cord-022561-rv5j1201	552	12	multiple	multiple	JJ
cord-022561-rv5j1201	552	13	hematopoietic	hematopoietic	JJ
cord-022561-rv5j1201	552	14	lineages	lineage	NNS
cord-022561-rv5j1201	552	15	,	,	,
cord-022561-rv5j1201	552	16	including	include	VBG
cord-022561-rv5j1201	552	17	megakaryocytes	megakaryocyte	NNS
cord-022561-rv5j1201	552	18	,	,	,
cord-022561-rv5j1201	552	19	 	 	_SP
cord-022561-rv5j1201	552	20	is	be	VBZ
cord-022561-rv5j1201	552	21	often	often	RB
cord-022561-rv5j1201	552	22	used	use	VBN
cord-022561-rv5j1201	552	23	interchangeably	interchangeably	RB
cord-022561-rv5j1201	552	24	with	with	IN
cord-022561-rv5j1201	552	25	erythrocytosis	erythrocytosis	NN
cord-022561-rv5j1201	552	26	,	,	,
cord-022561-rv5j1201	552	27	but	but	CC
cord-022561-rv5j1201	552	28	technically	technically	RB
cord-022561-rv5j1201	552	29	and	and	CC
cord-022561-rv5j1201	552	30	for	for	IN
cord-022561-rv5j1201	552	31	the	the	DT
cord-022561-rv5j1201	552	32	purposes	purpose	NNS
cord-022561-rv5j1201	552	33	of	of	IN
cord-022561-rv5j1201	552	34	this	this	DT
cord-022561-rv5j1201	552	35	chapter	chapter	NN
cord-022561-rv5j1201	552	36	,	,	,
cord-022561-rv5j1201	552	37	polycythemia	polycythemia	NN
cord-022561-rv5j1201	552	38	refers	refer	VBZ
cord-022561-rv5j1201	552	39	to	to	IN
cord-022561-rv5j1201	552	40	a	a	DT
cord-022561-rv5j1201	552	41	specific	specific	JJ
cord-022561-rv5j1201	552	42	type	type	NN
cord-022561-rv5j1201	552	43	of	of	IN
cord-022561-rv5j1201	552	44	leukemia	leukemia	NN
cord-022561-rv5j1201	552	45	called	call	VBN
cord-022561-rv5j1201	552	46	primary	primary	JJ
cord-022561-rv5j1201	552	47	erythrocytosis	erythrocytosis	NN
cord-022561-rv5j1201	552	48	or	or	CC
cord-022561-rv5j1201	552	49	polycythemia	polycythemia	NN
cord-022561-rv5j1201	552	50	vera	vera	NNP
cord-022561-rv5j1201	552	51	.	.	.
cord-022561-rv5j1201	553	1	Causes	cause	NNS
cord-022561-rv5j1201	553	2	of	of	IN
cord-022561-rv5j1201	553	3	erythrocytosis	erythrocytosis	NN
cord-022561-rv5j1201	553	4	are	be	VBP
cord-022561-rv5j1201	553	5	either	either	CC
cord-022561-rv5j1201	553	6	relative	relative	JJ
cord-022561-rv5j1201	553	7	or	or	CC
cord-022561-rv5j1201	553	8	absolute	absolute	JJ
cord-022561-rv5j1201	553	9	.	.	.
cord-022561-rv5j1201	554	1	Relative	relative	JJ
cord-022561-rv5j1201	554	2	erythrocytosis	erythrocytosis	NN
cord-022561-rv5j1201	554	3	results	result	VBZ
cord-022561-rv5j1201	554	4	from	from	IN
cord-022561-rv5j1201	554	5	a	a	DT
cord-022561-rv5j1201	554	6	fluid	fluid	JJ
cord-022561-rv5j1201	554	7	deficit	deficit	NN
cord-022561-rv5j1201	554	8	or	or	CC
cord-022561-rv5j1201	554	9	an	an	DT
cord-022561-rv5j1201	554	10	altered	altered	JJ
cord-022561-rv5j1201	554	11	distribution	distribution	NN
cord-022561-rv5j1201	554	12	of	of	IN
cord-022561-rv5j1201	554	13	erythrocytes	erythrocyte	NNS
cord-022561-rv5j1201	554	14	within	within	IN
cord-022561-rv5j1201	554	15	the	the	DT
cord-022561-rv5j1201	554	16	body	body	NN
cord-022561-rv5j1201	554	17	(	(	-LRB-
cord-022561-rv5j1201	554	18	i.e.	i.e.	FW
cord-022561-rv5j1201	554	19	,	,	,
cord-022561-rv5j1201	554	20	the	the	DT
cord-022561-rv5j1201	554	21	body	body	NN
cord-022561-rv5j1201	554	22	's	's	POS
cord-022561-rv5j1201	554	23	total	total	JJ
cord-022561-rv5j1201	554	24	erythrocyte	erythrocyte	NN
cord-022561-rv5j1201	554	25	mass	mass	NN
cord-022561-rv5j1201	554	26	of	of	IN
cord-022561-rv5j1201	554	27	generalized	generalized	JJ
cord-022561-rv5j1201	554	28	lymphadenopathy	lymphadenopathy	NN
cord-022561-rv5j1201	554	29	(	(	-LRB-
cord-022561-rv5j1201	554	30	e.g.	e.g.	RB
cord-022561-rv5j1201	554	31	,	,	,
cord-022561-rv5j1201	554	32	lymphoma	lymphoma	NN
cord-022561-rv5j1201	554	33	,	,	,
cord-022561-rv5j1201	554	34	blastomycosis	blastomycosis	NNP
cord-022561-rv5j1201	554	35	)	)	-RRB-
cord-022561-rv5j1201	554	36	.	.	.
cord-022561-rv5j1201	555	1	Some	some	DT
cord-022561-rv5j1201	555	2	hereditary	hereditary	JJ
cord-022561-rv5j1201	555	3	immunodeficiencies	immunodeficiency	NNS
cord-022561-rv5j1201	555	4	,	,	,
cord-022561-rv5j1201	555	5	such	such	JJ
cord-022561-rv5j1201	555	6	as	as	IN
cord-022561-rv5j1201	555	7	severe	severe	JJ
cord-022561-rv5j1201	555	8	combined	combine	VBN
cord-022561-rv5j1201	555	9	immunodeficiency	immunodeficiency	NN
cord-022561-rv5j1201	555	10	or	or	CC
cord-022561-rv5j1201	555	11	thymic	thymic	JJ
cord-022561-rv5j1201	555	12	aplasia	aplasia	NNP
cord-022561-rv5j1201	555	13	,	,	,
cord-022561-rv5j1201	555	14	can	can	MD
cord-022561-rv5j1201	555	15	cause	cause	VB
cord-022561-rv5j1201	555	16	lymphopenia	lymphopenia	NNP
cord-022561-rv5j1201	555	17	due	due	IN
cord-022561-rv5j1201	555	18	to	to	IN
cord-022561-rv5j1201	555	19	lymphoid	lymphoid	NNP
cord-022561-rv5j1201	555	20	aplasia	aplasia	NNP
cord-022561-rv5j1201	555	21	.	.	.
cord-022561-rv5j1201	556	1	Erythrocytosis	Erythrocytosis	NNP
cord-022561-rv5j1201	556	2	.	.	.
cord-022561-rv5j1201	557	1	An	an	DT
cord-022561-rv5j1201	557	2	increase	increase	NN
cord-022561-rv5j1201	557	3	in	in	IN
cord-022561-rv5j1201	557	4	the	the	DT
cord-022561-rv5j1201	557	5	measured	measure	VBN
cord-022561-rv5j1201	557	6	red	red	JJ
cord-022561-rv5j1201	557	7	cell	cell	NN
cord-022561-rv5j1201	557	8	mass	mass	NN
cord-022561-rv5j1201	557	9	above	above	IN
cord-022561-rv5j1201	557	10	the	the	DT
cord-022561-rv5j1201	557	11	normal	normal	JJ
cord-022561-rv5j1201	557	12	range	range	NN
cord-022561-rv5j1201	557	13	is	be	VBZ
cord-022561-rv5j1201	557	14	known	know	VBN
cord-022561-rv5j1201	557	15	as	as	IN
cord-022561-rv5j1201	557	16	erythrocytosis	erythrocytosis	NN
cord-022561-rv5j1201	557	17	.	.	.
cord-022561-rv5j1201	558	1	The	the	DT
cord-022561-rv5j1201	558	2	term	term	NN
cord-022561-rv5j1201	558	3	polycythemia	polycythemia	NN
cord-022561-rv5j1201	558	4	 	 	_SP
cord-022561-rv5j1201	558	5	Rarely	rarely	RB
cord-022561-rv5j1201	558	6	,	,	,
cord-022561-rv5j1201	558	7	an	an	DT
cord-022561-rv5j1201	558	8	Epo	Epo	NNP
cord-022561-rv5j1201	558	9	-	-	HYPH
cord-022561-rv5j1201	558	10	secreting	secrete	VBG
cord-022561-rv5j1201	558	11	tumor	tumor	NN
cord-022561-rv5j1201	558	12	may	may	MD
cord-022561-rv5j1201	558	13	cause	cause	VB
cord-022561-rv5j1201	558	14	inappropriately	inappropriately	RB
cord-022561-rv5j1201	558	15	elevated	elevate	VBN
cord-022561-rv5j1201	558	16	levels	level	NNS
cord-022561-rv5j1201	558	17	of	of	IN
cord-022561-rv5j1201	558	18	Epo	Epo	NNP
cord-022561-rv5j1201	558	19	in	in	IN
cord-022561-rv5j1201	558	20	the	the	DT
cord-022561-rv5j1201	558	21	absence	absence	NN
cord-022561-rv5j1201	558	22	of	of	IN
cord-022561-rv5j1201	558	23	hypoxia	hypoxia	NN
cord-022561-rv5j1201	558	24	.	.	.
cord-022561-rv5j1201	559	1	Absolute	absolute	JJ
cord-022561-rv5j1201	559	2	erythrocytosis	erythrocytosis	NN
cord-022561-rv5j1201	559	3	,	,	,
cord-022561-rv5j1201	559	4	whether	whether	IN
cord-022561-rv5j1201	559	5	primary	primary	JJ
cord-022561-rv5j1201	559	6	or	or	CC
cord-022561-rv5j1201	559	7	secondary	secondary	JJ
cord-022561-rv5j1201	559	8	,	,	,
cord-022561-rv5j1201	559	9	causes	cause	NNS
cord-022561-rv5j1201	559	10	increased	increase	VBN
cord-022561-rv5j1201	559	11	viscosity	viscosity	NN
cord-022561-rv5j1201	559	12	of	of	IN
cord-022561-rv5j1201	559	13	the	the	DT
cord-022561-rv5j1201	559	14	blood	blood	NN
cord-022561-rv5j1201	559	15	,	,	,
cord-022561-rv5j1201	559	16	resulting	result	VBG
cord-022561-rv5j1201	559	17	in	in	IN
cord-022561-rv5j1201	559	18	impaired	impaired	JJ
cord-022561-rv5j1201	559	19	blood	blood	NN
cord-022561-rv5j1201	559	20	flow	flow	NN
cord-022561-rv5j1201	559	21	and	and	CC
cord-022561-rv5j1201	559	22	microvasculature	microvasculature	NN
cord-022561-rv5j1201	559	23	distention	distention	NN
cord-022561-rv5j1201	559	24	.	.	.
cord-022561-rv5j1201	560	1	Affected	affected	JJ
cord-022561-rv5j1201	560	2	individuals	individual	NNS
cord-022561-rv5j1201	560	3	are	be	VBP
cord-022561-rv5j1201	560	4	at	at	IN
cord-022561-rv5j1201	560	5	increased	increase	VBN
cord-022561-rv5j1201	560	6	risk	risk	NN
cord-022561-rv5j1201	560	7	for	for	IN
cord-022561-rv5j1201	560	8	tissue	tissue	NN
cord-022561-rv5j1201	560	9	hypoxia	hypoxia	NN
cord-022561-rv5j1201	560	10	,	,	,
cord-022561-rv5j1201	560	11	thrombosis	thrombosis	NN
cord-022561-rv5j1201	560	12	,	,	,
cord-022561-rv5j1201	560	13	and	and	CC
cord-022561-rv5j1201	560	14	hemorrhage	hemorrhage	NN
cord-022561-rv5j1201	560	15	.	.	.
cord-022561-rv5j1201	561	1	Clinical	clinical	JJ
cord-022561-rv5j1201	561	2	signs	sign	NNS
cord-022561-rv5j1201	561	3	of	of	IN
cord-022561-rv5j1201	561	4	hyperviscosity	hyperviscosity	NN
cord-022561-rv5j1201	561	5	syndrome	syndrome	NN
cord-022561-rv5j1201	561	6	may	may	MD
cord-022561-rv5j1201	561	7	include	include	VB
cord-022561-rv5j1201	561	8	erythematous	erythematous	JJ
cord-022561-rv5j1201	561	9	mucous	mucous	JJ
cord-022561-rv5j1201	561	10	membranes	membrane	NNS
cord-022561-rv5j1201	561	11	(	(	-LRB-
cord-022561-rv5j1201	561	12	Fig	Fig	NNP
cord-022561-rv5j1201	561	13	.	.	.
cord-022561-rv5j1201	561	14	13	13	CD
cord-022561-rv5j1201	561	15	-	-	SYM
cord-022561-rv5j1201	561	16	17	17	CD
cord-022561-rv5j1201	561	17	)	)	-RRB-
cord-022561-rv5j1201	561	18	,	,	,
cord-022561-rv5j1201	561	19	prolonged	prolong	VBN
cord-022561-rv5j1201	561	20	capillary	capillary	JJ
cord-022561-rv5j1201	561	21	refill	refill	NN
cord-022561-rv5j1201	561	22	time	time	NN
cord-022561-rv5j1201	561	23	,	,	,
cord-022561-rv5j1201	561	24	prominent	prominent	JJ
cord-022561-rv5j1201	561	25	scleral	scleral	JJ
cord-022561-rv5j1201	561	26	vessels	vessel	NNS
cord-022561-rv5j1201	561	27	,	,	,
cord-022561-rv5j1201	561	28	evidence	evidence	NN
cord-022561-rv5j1201	561	29	of	of	IN
cord-022561-rv5j1201	561	30	thrombosis	thrombosis	NN
cord-022561-rv5j1201	561	31	or	or	CC
cord-022561-rv5j1201	561	32	hemorrhage	hemorrhage	NN
cord-022561-rv5j1201	561	33	,	,	,
cord-022561-rv5j1201	561	34	and	and	CC
cord-022561-rv5j1201	561	35	secondary	secondary	JJ
cord-022561-rv5j1201	561	36	signs	sign	NNS
cord-022561-rv5j1201	561	37	related	relate	VBN
cord-022561-rv5j1201	561	38	to	to	IN
cord-022561-rv5j1201	561	39	specific	specific	JJ
cord-022561-rv5j1201	561	40	organ	organ	NN
cord-022561-rv5j1201	561	41	systems	system	NNS
cord-022561-rv5j1201	561	42	affected	affect	VBN
cord-022561-rv5j1201	561	43	(	(	-LRB-
cord-022561-rv5j1201	561	44	e.g.	e.g.	RB
cord-022561-rv5j1201	561	45	,	,	,
cord-022561-rv5j1201	561	46	neurologic	neurologic	JJ
cord-022561-rv5j1201	561	47	and	and	CC
cord-022561-rv5j1201	561	48	cardiovascular	cardiovascular	JJ
cord-022561-rv5j1201	561	49	signs	sign	NNS
cord-022561-rv5j1201	561	50	)	)	-RRB-
cord-022561-rv5j1201	561	51	.	.	.
cord-022561-rv5j1201	562	1	Neutrophilia	Neutrophilia	NNP
cord-022561-rv5j1201	562	2	.	.	.
cord-022561-rv5j1201	563	1	Neutrophilia	Neutrophilia	NNP
cord-022561-rv5j1201	563	2	,	,	,
cord-022561-rv5j1201	563	3	an	an	DT
cord-022561-rv5j1201	563	4	increased	increase	VBN
cord-022561-rv5j1201	563	5	blood	blood	NN
cord-022561-rv5j1201	563	6	concentration	concentration	NN
cord-022561-rv5j1201	563	7	of	of	IN
cord-022561-rv5j1201	563	8	neutrophils	neutrophil	NNS
cord-022561-rv5j1201	563	9	,	,	,
cord-022561-rv5j1201	563	10	occurs	occur	VBZ
cord-022561-rv5j1201	563	11	in	in	IN
cord-022561-rv5j1201	563	12	response	response	NN
cord-022561-rv5j1201	563	13	to	to	IN
cord-022561-rv5j1201	563	14	a	a	DT
cord-022561-rv5j1201	563	15	number	number	NN
cord-022561-rv5j1201	563	16	of	of	IN
cord-022561-rv5j1201	563	17	different	different	JJ
cord-022561-rv5j1201	563	18	stimuli	stimulus	NNS
cord-022561-rv5j1201	563	19	,	,	,
cord-022561-rv5j1201	563	20	which	which	WDT
cord-022561-rv5j1201	563	21	are	be	VBP
cord-022561-rv5j1201	563	22	not	not	RB
cord-022561-rv5j1201	563	23	mutually	mutually	RB
cord-022561-rv5j1201	563	24	exclusive	exclusive	JJ
cord-022561-rv5j1201	563	25	.	.	.
cord-022561-rv5j1201	564	1	Major	major	JJ
cord-022561-rv5j1201	564	2	mechanisms	mechanism	NNS
cord-022561-rv5j1201	564	3	of	of	IN
cord-022561-rv5j1201	564	4	neutrophilia	neutrophilia	NNS
cord-022561-rv5j1201	564	5	are	be	VBP
cord-022561-rv5j1201	564	6	shown	show	VBN
cord-022561-rv5j1201	564	7	in	in	IN
cord-022561-rv5j1201	564	8	Fig	Fig	NNP
cord-022561-rv5j1201	564	9	.	.	.
cord-022561-rv5j1201	565	1	13	13	CD
cord-022561-rv5j1201	565	2	-	-	SYM
cord-022561-rv5j1201	565	3	18	18	CD
cord-022561-rv5j1201	565	4	.	.	.
cord-022561-rv5j1201	566	1	Understanding	understand	VBG
cord-022561-rv5j1201	566	2	the	the	DT
cord-022561-rv5j1201	566	3	CBC	CBC	NNP
cord-022561-rv5j1201	566	4	findings	finding	NNS
cord-022561-rv5j1201	566	5	characteristic	characteristic	JJ
cord-022561-rv5j1201	566	6	of	of	IN
cord-022561-rv5j1201	566	7	these	these	DT
cord-022561-rv5j1201	566	8	responses	response	NNS
cord-022561-rv5j1201	566	9	is	be	VBZ
cord-022561-rv5j1201	566	10	an	an	DT
cord-022561-rv5j1201	566	11	important	important	JJ
cord-022561-rv5j1201	566	12	part	part	NN
cord-022561-rv5j1201	566	13	of	of	IN
cord-022561-rv5j1201	566	14	clinical	clinical	JJ
cord-022561-rv5j1201	566	15	veterinary	veterinary	JJ
cord-022561-rv5j1201	566	16	medicine	medicine	NN
cord-022561-rv5j1201	566	17	.	.	.
cord-022561-rv5j1201	567	1	Inflammation	inflammation	NN
cord-022561-rv5j1201	567	2	can	can	MD
cord-022561-rv5j1201	567	3	result	result	VB
cord-022561-rv5j1201	567	4	in	in	IN
cord-022561-rv5j1201	567	5	neutropenia	neutropenia	NN
cord-022561-rv5j1201	567	6	,	,	,
cord-022561-rv5j1201	567	7	as	as	IN
cord-022561-rv5j1201	567	8	discussed	discuss	VBN
cord-022561-rv5j1201	567	9	earlier	early	RBR
cord-022561-rv5j1201	567	10	,	,	,
cord-022561-rv5j1201	567	11	or	or	CC
cord-022561-rv5j1201	567	12	neutrophilia	neutrophilia	NNP
cord-022561-rv5j1201	567	13	,	,	,
cord-022561-rv5j1201	567	14	as	as	IN
cord-022561-rv5j1201	567	15	discussed	discuss	VBN
cord-022561-rv5j1201	567	16	next	next	RB
cord-022561-rv5j1201	567	17	.	.	.
cord-022561-rv5j1201	568	1	However	however	RB
cord-022561-rv5j1201	568	2	,	,	,
cord-022561-rv5j1201	568	3	before	before	IN
cord-022561-rv5j1201	568	4	moving	move	VBG
cord-022561-rv5j1201	568	5	on	on	RP
cord-022561-rv5j1201	568	6	to	to	IN
cord-022561-rv5j1201	568	7	a	a	DT
cord-022561-rv5j1201	568	8	discussion	discussion	NN
cord-022561-rv5j1201	568	9	of	of	IN
cord-022561-rv5j1201	568	10	inflammatory	inflammatory	JJ
cord-022561-rv5j1201	568	11	neutrophilia	neutrophilia	NNP
cord-022561-rv5j1201	568	12	and	and	CC
cord-022561-rv5j1201	568	13	the	the	DT
cord-022561-rv5j1201	568	14	so	so	RB
cord-022561-rv5j1201	568	15	-	-	HYPH
cord-022561-rv5j1201	568	16	called	call	VBN
cord-022561-rv5j1201	568	17	left	left	JJ
cord-022561-rv5j1201	568	18	shift	shift	NN
cord-022561-rv5j1201	568	19	,	,	,
cord-022561-rv5j1201	568	20	it	-PRON-	PRP
cord-022561-rv5j1201	568	21	is	be	VBZ
cord-022561-rv5j1201	568	22	important	important	JJ
cord-022561-rv5j1201	568	23	to	to	TO
cord-022561-rv5j1201	568	24	mention	mention	VB
cord-022561-rv5j1201	568	25	two	two	CD
cord-022561-rv5j1201	568	26	other	other	JJ
cord-022561-rv5j1201	568	27	common	common	NN
cord-022561-rv5j1201	568	28	is	be	VBZ
cord-022561-rv5j1201	568	29	not	not	RB
cord-022561-rv5j1201	568	30	increased	increase	VBN
cord-022561-rv5j1201	568	31	)	)	-RRB-
cord-022561-rv5j1201	568	32	.	.	.
cord-022561-rv5j1201	569	1	It	-PRON-	PRP
cord-022561-rv5j1201	569	2	occurs	occur	VBZ
cord-022561-rv5j1201	569	3	most	most	RBS
cord-022561-rv5j1201	569	4	frequently	frequently	RB
cord-022561-rv5j1201	569	5	with	with	IN
cord-022561-rv5j1201	569	6	dehydration	dehydration	NN
cord-022561-rv5j1201	569	7	,	,	,
cord-022561-rv5j1201	569	8	when	when	WRB
cord-022561-rv5j1201	569	9	the	the	DT
cord-022561-rv5j1201	569	10	decreased	decreased	JJ
cord-022561-rv5j1201	569	11	proportion	proportion	NN
cord-022561-rv5j1201	569	12	of	of	IN
cord-022561-rv5j1201	569	13	water	water	NN
cord-022561-rv5j1201	569	14	in	in	IN
cord-022561-rv5j1201	569	15	the	the	DT
cord-022561-rv5j1201	569	16	blood	blood	NN
cord-022561-rv5j1201	569	17	results	result	NNS
cord-022561-rv5j1201	569	18	in	in	IN
cord-022561-rv5j1201	569	19	hemoconcentration	hemoconcentration	NN
cord-022561-rv5j1201	569	20	.	.	.
cord-022561-rv5j1201	570	1	It	-PRON-	PRP
cord-022561-rv5j1201	570	2	is	be	VBZ
cord-022561-rv5j1201	570	3	observed	observe	VBN
cord-022561-rv5j1201	570	4	less	less	RBR
cord-022561-rv5j1201	570	5	frequently	frequently	RB
cord-022561-rv5j1201	570	6	with	with	IN
cord-022561-rv5j1201	570	7	epinephrine	epinephrine	NN
cord-022561-rv5j1201	570	8	-	-	HYPH
cord-022561-rv5j1201	570	9	mediated	mediate	VBN
cord-022561-rv5j1201	570	10	splenic	splenic	JJ
cord-022561-rv5j1201	570	11	contraction	contraction	NN
cord-022561-rv5j1201	570	12	,	,	,
cord-022561-rv5j1201	570	13	wherein	wherein	WRB
cord-022561-rv5j1201	570	14	erythrocytes	erythrocyte	NNS
cord-022561-rv5j1201	570	15	move	move	VBP
cord-022561-rv5j1201	570	16	from	from	IN
cord-022561-rv5j1201	570	17	the	the	DT
cord-022561-rv5j1201	570	18	spleen	spleen	NN
cord-022561-rv5j1201	570	19	into	into	IN
cord-022561-rv5j1201	570	20	peripheral	peripheral	JJ
cord-022561-rv5j1201	570	21	circulation	circulation	NN
cord-022561-rv5j1201	570	22	.	.	.
cord-022561-rv5j1201	571	1	Erythrocytosis	erythrocytosis	NN
cord-022561-rv5j1201	571	2	from	from	IN
cord-022561-rv5j1201	571	3	splenic	splenic	JJ
cord-022561-rv5j1201	571	4	contraction	contraction	NN
cord-022561-rv5j1201	571	5	occurs	occur	VBZ
cord-022561-rv5j1201	571	6	to	to	IN
cord-022561-rv5j1201	571	7	the	the	DT
cord-022561-rv5j1201	571	8	most	most	RBS
cord-022561-rv5j1201	571	9	pronounced	pronounced	JJ
cord-022561-rv5j1201	571	10	degree	degree	NN
cord-022561-rv5j1201	571	11	in	in	IN
cord-022561-rv5j1201	571	12	horses	horse	NNS
cord-022561-rv5j1201	571	13	and	and	CC
cord-022561-rv5j1201	571	14	cats	cat	NNS
cord-022561-rv5j1201	571	15	,	,	,
cord-022561-rv5j1201	571	16	especially	especially	RB
cord-022561-rv5j1201	571	17	in	in	IN
cord-022561-rv5j1201	571	18	young	young	JJ
cord-022561-rv5j1201	571	19	,	,	,
cord-022561-rv5j1201	571	20	healthy	healthy	JJ
cord-022561-rv5j1201	571	21	animals	animal	NNS
cord-022561-rv5j1201	571	22	.	.	.
cord-022561-rv5j1201	572	1	Absolute	absolute	JJ
cord-022561-rv5j1201	572	2	erythrocytosis	erythrocytosis	NN
cord-022561-rv5j1201	572	3	is	be	VBZ
cord-022561-rv5j1201	572	4	a	a	DT
cord-022561-rv5j1201	572	5	true	true	JJ
cord-022561-rv5j1201	572	6	increase	increase	NN
cord-022561-rv5j1201	572	7	in	in	IN
cord-022561-rv5j1201	572	8	red	red	JJ
cord-022561-rv5j1201	572	9	blood	blood	NN
cord-022561-rv5j1201	572	10	cell	cell	NN
cord-022561-rv5j1201	572	11	mass	mass	NN
cord-022561-rv5j1201	572	12	due	due	JJ
cord-022561-rv5j1201	572	13	to	to	IN
cord-022561-rv5j1201	572	14	erythroid	erythroid	JJ
cord-022561-rv5j1201	572	15	neoplasia	neoplasia	NN
cord-022561-rv5j1201	572	16	or	or	CC
cord-022561-rv5j1201	572	17	hyperplasia	hyperplasia	NN
cord-022561-rv5j1201	572	18	and	and	CC
cord-022561-rv5j1201	572	19	includes	include	VBZ
cord-022561-rv5j1201	572	20	causes	cause	NNS
cord-022561-rv5j1201	572	21	of	of	IN
cord-022561-rv5j1201	572	22	primary	primary	JJ
cord-022561-rv5j1201	572	23	and	and	CC
cord-022561-rv5j1201	572	24	secondary	secondary	JJ
cord-022561-rv5j1201	572	25	erythrocytosis	erythrocytosis	NN
cord-022561-rv5j1201	572	26	.	.	.
cord-022561-rv5j1201	573	1	Primary	primary	JJ
cord-022561-rv5j1201	573	2	erythrocytosis	erythrocytosis	NN
cord-022561-rv5j1201	573	3	,	,	,
cord-022561-rv5j1201	573	4	or	or	CC
cord-022561-rv5j1201	573	5	polycythemia	polycythemia	NN
cord-022561-rv5j1201	573	6	vera	vera	NN
cord-022561-rv5j1201	573	7	,	,	,
cord-022561-rv5j1201	573	8	is	be	VBZ
cord-022561-rv5j1201	573	9	a	a	DT
cord-022561-rv5j1201	573	10	neoplastic	neoplastic	JJ
cord-022561-rv5j1201	573	11	proliferation	proliferation	NN
cord-022561-rv5j1201	573	12	of	of	IN
cord-022561-rv5j1201	573	13	erythroid	erythroid	NN
cord-022561-rv5j1201	573	14	cells	cell	NNS
cord-022561-rv5j1201	573	15	with	with	IN
cord-022561-rv5j1201	573	16	a	a	DT
cord-022561-rv5j1201	573	17	predominance	predominance	NN
cord-022561-rv5j1201	573	18	of	of	IN
cord-022561-rv5j1201	573	19	mature	mature	JJ
cord-022561-rv5j1201	573	20	erythrocytes	erythrocyte	NNS
cord-022561-rv5j1201	573	21	.	.	.
cord-022561-rv5j1201	574	1	Diagnosis	diagnosis	NN
cord-022561-rv5j1201	574	2	is	be	VBZ
cord-022561-rv5j1201	574	3	based	base	VBN
cord-022561-rv5j1201	574	4	on	on	IN
cord-022561-rv5j1201	574	5	a	a	DT
cord-022561-rv5j1201	574	6	marked	marked	JJ
cord-022561-rv5j1201	574	7	increase	increase	NN
cord-022561-rv5j1201	574	8	in	in	IN
cord-022561-rv5j1201	574	9	red	red	JJ
cord-022561-rv5j1201	574	10	cell	cell	NN
cord-022561-rv5j1201	574	11	mass	mass	NN
cord-022561-rv5j1201	574	12	(	(	-LRB-
cord-022561-rv5j1201	574	13	hematocrit	hematocrit	NN
cord-022561-rv5j1201	574	14	in	in	IN
cord-022561-rv5j1201	574	15	normally	normally	RB
cord-022561-rv5j1201	574	16	hydrated	hydrated	JJ
cord-022561-rv5j1201	574	17	dogs	dog	NNS
cord-022561-rv5j1201	574	18	ranges	range	VBZ
cord-022561-rv5j1201	574	19	from	from	IN
cord-022561-rv5j1201	574	20	65	65	CD
cord-022561-rv5j1201	574	21	%	%	NN
cord-022561-rv5j1201	574	22	to	to	IN
cord-022561-rv5j1201	574	23	>	>	XX
cord-022561-rv5j1201	574	24	80	80	CD
cord-022561-rv5j1201	574	25	%	%	NN
cord-022561-rv5j1201	574	26	)	)	-RRB-
cord-022561-rv5j1201	574	27	,	,	,
cord-022561-rv5j1201	574	28	an	an	DT
cord-022561-rv5j1201	574	29	absence	absence	NN
cord-022561-rv5j1201	574	30	of	of	IN
cord-022561-rv5j1201	574	31	hypoxemia	hypoxemia	NN
cord-022561-rv5j1201	574	32	,	,	,
cord-022561-rv5j1201	574	33	an	an	DT
cord-022561-rv5j1201	574	34	absence	absence	NN
cord-022561-rv5j1201	574	35	of	of	IN
cord-022561-rv5j1201	574	36	other	other	JJ
cord-022561-rv5j1201	574	37	tumors	tumor	NNS
cord-022561-rv5j1201	574	38	,	,	,
cord-022561-rv5j1201	574	39	and	and	CC
cord-022561-rv5j1201	574	40	a	a	DT
cord-022561-rv5j1201	574	41	normal	normal	JJ
cord-022561-rv5j1201	574	42	or	or	CC
cord-022561-rv5j1201	574	43	decreased	decrease	VBD
cord-022561-rv5j1201	574	44	plasma	plasma	NN
cord-022561-rv5j1201	574	45	Epo	Epo	NNP
cord-022561-rv5j1201	574	46	concentration	concentration	NN
cord-022561-rv5j1201	574	47	.	.	.
cord-022561-rv5j1201	575	1	Secondary	secondary	JJ
cord-022561-rv5j1201	575	2	erythrocytosis	erythrocytosis	NN
cord-022561-rv5j1201	575	3	refers	refer	VBZ
cord-022561-rv5j1201	575	4	to	to	IN
cord-022561-rv5j1201	575	5	Epo	Epo	NNP
cord-022561-rv5j1201	575	6	-	-	HYPH
cord-022561-rv5j1201	575	7	mediated	mediate	VBN
cord-022561-rv5j1201	575	8	erythroid	erythroid	NN
cord-022561-rv5j1201	575	9	hyperplasia	hyperplasia	NN
cord-022561-rv5j1201	575	10	causing	cause	VBG
cord-022561-rv5j1201	575	11	an	an	DT
cord-022561-rv5j1201	575	12	increased	increase	VBN
cord-022561-rv5j1201	575	13	red	red	JJ
cord-022561-rv5j1201	575	14	blood	blood	NN
cord-022561-rv5j1201	575	15	cell	cell	NN
cord-022561-rv5j1201	575	16	mass	mass	NN
cord-022561-rv5j1201	575	17	.	.	.
cord-022561-rv5j1201	576	1	The	the	DT
cord-022561-rv5j1201	576	2	erythroid	erythroid	JJ
cord-022561-rv5j1201	576	3	hyperplasia	hyperplasia	NN
cord-022561-rv5j1201	576	4	may	may	MD
cord-022561-rv5j1201	576	5	be	be	VB
cord-022561-rv5j1201	576	6	an	an	DT
cord-022561-rv5j1201	576	7	appropriate	appropriate	JJ
cord-022561-rv5j1201	576	8	response	response	NN
cord-022561-rv5j1201	576	9	to	to	IN
cord-022561-rv5j1201	576	10	chronic	chronic	JJ
cord-022561-rv5j1201	576	11	hypoxia	hypoxia	NN
cord-022561-rv5j1201	576	12	,	,	,
cord-022561-rv5j1201	576	13	such	such	JJ
cord-022561-rv5j1201	576	14	as	as	IN
cord-022561-rv5j1201	576	15	occurs	occur	VBZ
cord-022561-rv5j1201	576	16	with	with	IN
cord-022561-rv5j1201	576	17	right	right	NN
cord-022561-rv5j1201	576	18	-	-	HYPH
cord-022561-rv5j1201	576	19	to	to	IN
cord-022561-rv5j1201	576	20	-	-	HYPH
cord-022561-rv5j1201	576	21	left	leave	VBN
cord-022561-rv5j1201	576	22	cardiac	cardiac	JJ
cord-022561-rv5j1201	576	23	shunts	shunt	NNS
cord-022561-rv5j1201	576	24	or	or	CC
cord-022561-rv5j1201	576	25	chronic	chronic	JJ
cord-022561-rv5j1201	576	26	pulmonary	pulmonary	JJ
cord-022561-rv5j1201	576	27	Inflammatory	inflammatory	JJ
cord-022561-rv5j1201	576	28	mediators	mediator	NNS
cord-022561-rv5j1201	576	29	,	,	,
cord-022561-rv5j1201	576	30	including	include	VBG
cord-022561-rv5j1201	576	31	interleukin-1	interleukin-1	NN
cord-022561-rv5j1201	576	32	(	(	-LRB-
cord-022561-rv5j1201	576	33	IL-1	IL-1	NNP
cord-022561-rv5j1201	576	34	)	)	-RRB-
cord-022561-rv5j1201	576	35	,	,	,
cord-022561-rv5j1201	576	36	interleukin-6	interleukin-6	NNP
cord-022561-rv5j1201	576	37	(	(	-LRB-
cord-022561-rv5j1201	576	38	IL-6	IL-6	NNP
cord-022561-rv5j1201	576	39	)	)	-RRB-
cord-022561-rv5j1201	576	40	,	,	,
cord-022561-rv5j1201	576	41	interferon	interferon	NN
cord-022561-rv5j1201	576	42	(	(	-LRB-
cord-022561-rv5j1201	576	43	INF	INF	NNP
cord-022561-rv5j1201	576	44	)	)	-RRB-
cord-022561-rv5j1201	576	45	,	,	,
cord-022561-rv5j1201	576	46	and	and	CC
cord-022561-rv5j1201	576	47	tumor	tumor	NN
cord-022561-rv5j1201	576	48	necrosis	necrosis	NN
cord-022561-rv5j1201	576	49	factor	factor	NN
cord-022561-rv5j1201	576	50	(	(	-LRB-
cord-022561-rv5j1201	576	51	TNF	TNF	NNP
cord-022561-rv5j1201	576	52	)	)	-RRB-
cord-022561-rv5j1201	576	53	,	,	,
cord-022561-rv5j1201	576	54	cause	cause	VB
cord-022561-rv5j1201	576	55	anemia	anemia	NN
cord-022561-rv5j1201	576	56	of	of	IN
cord-022561-rv5j1201	576	57	inflammatory	inflammatory	JJ
cord-022561-rv5j1201	576	58	disease	disease	NN
cord-022561-rv5j1201	576	59	due	due	JJ
cord-022561-rv5j1201	576	60	to	to	IN
cord-022561-rv5j1201	576	61	oxidative	oxidative	JJ
cord-022561-rv5j1201	576	62	hemolysis	hemolysis	NN
cord-022561-rv5j1201	576	63	,	,	,
cord-022561-rv5j1201	576	64	iron	iron	NN
cord-022561-rv5j1201	576	65	sequestration	sequestration	NN
cord-022561-rv5j1201	576	66	within	within	IN
cord-022561-rv5j1201	576	67	enterocytes	enterocyte	NNS
cord-022561-rv5j1201	576	68	and	and	CC
cord-022561-rv5j1201	576	69	macrophages	macrophage	NNS
cord-022561-rv5j1201	576	70	,	,	,
cord-022561-rv5j1201	576	71	and	and	CC
cord-022561-rv5j1201	576	72	impaired	impaired	JJ
cord-022561-rv5j1201	576	73	erythroid	erythroid	JJ
cord-022561-rv5j1201	576	74	responsiveness	responsiveness	NN
cord-022561-rv5j1201	576	75	to	to	IN
cord-022561-rv5j1201	576	76	erythropoietin	erythropoietin	NN
cord-022561-rv5j1201	576	77	(	(	-LRB-
cord-022561-rv5j1201	576	78	Epo	Epo	NNP
cord-022561-rv5j1201	576	79	)	)	-RRB-
cord-022561-rv5j1201	576	80	.	.	.
cord-022561-rv5j1201	577	1	During	during	IN
cord-022561-rv5j1201	577	2	homeostasis	homeostasis	NN
cord-022561-rv5j1201	577	3	the	the	DT
cord-022561-rv5j1201	577	4	membrane	membrane	NN
cord-022561-rv5j1201	577	5	transport	transport	NN
cord-022561-rv5j1201	577	6	molecule	molecule	NN
cord-022561-rv5j1201	577	7	,	,	,
cord-022561-rv5j1201	577	8	ferroportin	ferroportin	NNP
cord-022561-rv5j1201	577	9	,	,	,
cord-022561-rv5j1201	577	10	transports	transport	VBZ
cord-022561-rv5j1201	577	11	iron	iron	NN
cord-022561-rv5j1201	577	12	from	from	IN
cord-022561-rv5j1201	577	13	the	the	DT
cord-022561-rv5j1201	577	14	cytosol	cytosol	NN
cord-022561-rv5j1201	577	15	to	to	IN
cord-022561-rv5j1201	577	16	the	the	DT
cord-022561-rv5j1201	577	17	extracellular	extracellular	JJ
cord-022561-rv5j1201	577	18	space	space	NN
cord-022561-rv5j1201	577	19	.	.	.
cord-022561-rv5j1201	578	1	The	the	DT
cord-022561-rv5j1201	578	2	iron	iron	NN
cord-022561-rv5j1201	578	3	is	be	VBZ
cord-022561-rv5j1201	578	4	then	then	RB
cord-022561-rv5j1201	578	5	used	use	VBN
cord-022561-rv5j1201	578	6	for	for	IN
cord-022561-rv5j1201	578	7	various	various	JJ
cord-022561-rv5j1201	578	8	physiologic	physiologic	JJ
cord-022561-rv5j1201	578	9	processes	process	NNS
cord-022561-rv5j1201	578	10	,	,	,
cord-022561-rv5j1201	578	11	including	include	VBG
cord-022561-rv5j1201	578	12	hemoglobin	hemoglobin	NN
cord-022561-rv5j1201	578	13	production	production	NN
cord-022561-rv5j1201	578	14	within	within	IN
cord-022561-rv5j1201	578	15	bone	bone	NN
cord-022561-rv5j1201	578	16	marrow	marrow	NN
cord-022561-rv5j1201	578	17	erythroid	erythroid	NN
cord-022561-rv5j1201	578	18	precursors	precursor	NNS
cord-022561-rv5j1201	578	19	.	.	.
cord-022561-rv5j1201	579	1	During	during	IN
cord-022561-rv5j1201	579	2	times	time	NNS
cord-022561-rv5j1201	579	3	of	of	IN
cord-022561-rv5j1201	579	4	inflammation	inflammation	NN
cord-022561-rv5j1201	579	5	the	the	DT
cord-022561-rv5j1201	579	6	liver	liver	NN
cord-022561-rv5j1201	579	7	increases	increase	NNS
cord-022561-rv5j1201	579	8	production	production	NN
cord-022561-rv5j1201	579	9	of	of	IN
cord-022561-rv5j1201	579	10	hepcidin	hepcidin	NNP
cord-022561-rv5j1201	579	11	,	,	,
cord-022561-rv5j1201	579	12	which	which	WDT
cord-022561-rv5j1201	579	13	binds	bind	VBZ
cord-022561-rv5j1201	579	14	ferroportin	ferroportin	NN
cord-022561-rv5j1201	579	15	and	and	CC
cord-022561-rv5j1201	579	16	causes	cause	VBZ
cord-022561-rv5j1201	579	17	its	-PRON-	PRP$
cord-022561-rv5j1201	579	18	internalization	internalization	NN
cord-022561-rv5j1201	579	19	and	and	CC
cord-022561-rv5j1201	579	20	lysosomal	lysosomal	JJ
cord-022561-rv5j1201	579	21	degradation	degradation	NN
cord-022561-rv5j1201	579	22	.	.	.
cord-022561-rv5j1201	580	1	With	with	IN
cord-022561-rv5j1201	580	2	fewer	few	JJR
cord-022561-rv5j1201	580	3	membrane	membrane	NN
cord-022561-rv5j1201	580	4	ferroportin	ferroportin	NN
cord-022561-rv5j1201	580	5	molecules	molecule	NNS
cord-022561-rv5j1201	580	6	,	,	,
cord-022561-rv5j1201	580	7	less	less	JJR
cord-022561-rv5j1201	580	8	iron	iron	NN
cord-022561-rv5j1201	580	9	is	be	VBZ
cord-022561-rv5j1201	580	10	absorbed	absorb	VBN
cord-022561-rv5j1201	580	11	from	from	IN
cord-022561-rv5j1201	580	12	the	the	DT
cord-022561-rv5j1201	580	13	diet	diet	NN
cord-022561-rv5j1201	580	14	and	and	CC
cord-022561-rv5j1201	580	15	mobilized	mobilize	VBD
cord-022561-rv5j1201	580	16	from	from	IN
cord-022561-rv5j1201	580	17	macrophages	macrophage	NNS
cord-022561-rv5j1201	580	18	.	.	.
cord-022561-rv5j1201	581	1	RBC	RBC	NNP
cord-022561-rv5j1201	581	2	,	,	,
cord-022561-rv5j1201	581	3	Red	red	JJ
cord-022561-rv5j1201	581	4	blood	blood	NN
cord-022561-rv5j1201	581	5	cell	cell	NN
cord-022561-rv5j1201	581	6	.	.	.
cord-022561-rv5j1201	582	1	(	(	-LRB-
cord-022561-rv5j1201	582	2	Of	of	RB
cord-022561-rv5j1201	582	3	course	course	RB
cord-022561-rv5j1201	582	4	,	,	,
cord-022561-rv5j1201	582	5	neutrophilia	neutrophilia	NNP
cord-022561-rv5j1201	582	6	may	may	MD
cord-022561-rv5j1201	582	7	also	also	RB
cord-022561-rv5j1201	582	8	indicate	indicate	VB
cord-022561-rv5j1201	582	9	inflammation	inflammation	NN
cord-022561-rv5j1201	582	10	,	,	,
cord-022561-rv5j1201	582	11	and	and	CC
cord-022561-rv5j1201	582	12	inflammatory	inflammatory	JJ
cord-022561-rv5j1201	582	13	stimuli	stimulus	NNS
cord-022561-rv5j1201	582	14	of	of	IN
cord-022561-rv5j1201	582	15	varying	vary	VBG
cord-022561-rv5j1201	582	16	magnitude	magnitude	NN
cord-022561-rv5j1201	582	17	and	and	CC
cord-022561-rv5j1201	582	18	duration	duration	NN
cord-022561-rv5j1201	582	19	produce	produce	VBP
cord-022561-rv5j1201	582	20	different	different	JJ
cord-022561-rv5j1201	582	21	patterns	pattern	NNS
cord-022561-rv5j1201	582	22	of	of	IN
cord-022561-rv5j1201	582	23	neutrophilia	neutrophilia	NNP
cord-022561-rv5j1201	582	24	.	.	.
cord-022561-rv5j1201	583	1	A	a	DT
cord-022561-rv5j1201	583	2	classic	classic	JJ
cord-022561-rv5j1201	583	3	hematologic	hematologic	JJ
cord-022561-rv5j1201	583	4	finding	finding	NN
cord-022561-rv5j1201	583	5	in	in	IN
cord-022561-rv5j1201	583	6	patients	patient	NNS
cord-022561-rv5j1201	583	7	with	with	IN
cord-022561-rv5j1201	583	8	increased	increase	VBN
cord-022561-rv5j1201	583	9	demand	demand	NN
cord-022561-rv5j1201	583	10	for	for	IN
cord-022561-rv5j1201	583	11	neutrophils	neutrophil	NNS
cord-022561-rv5j1201	583	12	is	be	VBZ
cord-022561-rv5j1201	583	13	the	the	DT
cord-022561-rv5j1201	583	14	presence	presence	NN
cord-022561-rv5j1201	583	15	of	of	IN
cord-022561-rv5j1201	583	16	immature	immature	JJ
cord-022561-rv5j1201	583	17	forms	form	NNS
cord-022561-rv5j1201	583	18	in	in	IN
cord-022561-rv5j1201	583	19	the	the	DT
cord-022561-rv5j1201	583	20	blood	blood	NN
cord-022561-rv5j1201	583	21	,	,	,
cord-022561-rv5j1201	583	22	known	know	VBN
cord-022561-rv5j1201	583	23	as	as	IN
cord-022561-rv5j1201	583	24	a	a	DT
cord-022561-rv5j1201	583	25	left	left	JJ
cord-022561-rv5j1201	583	26	shift	shift	NN
cord-022561-rv5j1201	583	27	.	.	.
cord-022561-rv5j1201	584	1	Not	not	RB
cord-022561-rv5j1201	584	2	all	all	DT
cord-022561-rv5j1201	584	3	inflammatory	inflammatory	JJ
cord-022561-rv5j1201	584	4	responses	response	NNS
cord-022561-rv5j1201	584	5	have	have	VBP
cord-022561-rv5j1201	584	6	a	a	DT
cord-022561-rv5j1201	584	7	left	left	JJ
cord-022561-rv5j1201	584	8	shift	shift	NN
cord-022561-rv5j1201	584	9	,	,	,
cord-022561-rv5j1201	584	10	but	but	CC
cord-022561-rv5j1201	584	11	the	the	DT
cord-022561-rv5j1201	584	12	presence	presence	NN
cord-022561-rv5j1201	584	13	of	of	IN
cord-022561-rv5j1201	584	14	a	a	DT
cord-022561-rv5j1201	584	15	left	left	JJ
cord-022561-rv5j1201	584	16	shift	shift	NN
cord-022561-rv5j1201	584	17	almost	almost	RB
cord-022561-rv5j1201	584	18	always	always	RB
cord-022561-rv5j1201	584	19	signifies	signify	VBZ
cord-022561-rv5j1201	584	20	active	active	JJ
cord-022561-rv5j1201	584	21	demand	demand	NN
cord-022561-rv5j1201	584	22	for	for	IN
cord-022561-rv5j1201	584	23	neutrophils	neutrophil	NNS
cord-022561-rv5j1201	584	24	in	in	IN
cord-022561-rv5j1201	584	25	the	the	DT
cord-022561-rv5j1201	584	26	tissue	tissue	NN
cord-022561-rv5j1201	584	27	.	.	.
cord-022561-rv5j1201	585	1	The	the	DT
cord-022561-rv5j1201	585	2	magnitude	magnitude	NN
cord-022561-rv5j1201	585	3	of	of	IN
cord-022561-rv5j1201	585	4	a	a	DT
cord-022561-rv5j1201	585	5	left	left	JJ
cord-022561-rv5j1201	585	6	shift	shift	NN
cord-022561-rv5j1201	585	7	is	be	VBZ
cord-022561-rv5j1201	585	8	assessed	assess	VBN
cord-022561-rv5j1201	585	9	by	by	IN
cord-022561-rv5j1201	585	10	the	the	DT
cord-022561-rv5j1201	585	11	number	number	NN
cord-022561-rv5j1201	585	12	of	of	IN
cord-022561-rv5j1201	585	13	immature	immature	JJ
cord-022561-rv5j1201	585	14	cells	cell	NNS
cord-022561-rv5j1201	585	15	and	and	CC
cord-022561-rv5j1201	585	16	their	-PRON-	PRP$
cord-022561-rv5j1201	585	17	degree	degree	NN
cord-022561-rv5j1201	585	18	of	of	IN
cord-022561-rv5j1201	585	19	immaturity	immaturity	NN
cord-022561-rv5j1201	585	20	.	.	.
cord-022561-rv5j1201	586	1	The	the	DT
cord-022561-rv5j1201	586	2	mildest	mild	JJS
cord-022561-rv5j1201	586	3	form	form	NN
cord-022561-rv5j1201	586	4	is	be	VBZ
cord-022561-rv5j1201	586	5	characterized	characterize	VBN
cord-022561-rv5j1201	586	6	by	by	IN
cord-022561-rv5j1201	586	7	increased	increase	VBN
cord-022561-rv5j1201	586	8	numbers	number	NNS
cord-022561-rv5j1201	586	9	of	of	IN
cord-022561-rv5j1201	586	10	band	band	NN
cord-022561-rv5j1201	586	11	neutrophils	neutrophil	NNS
cord-022561-rv5j1201	586	12	,	,	,
cord-022561-rv5j1201	586	13	the	the	DT
cord-022561-rv5j1201	586	14	immediate	immediate	JJ
cord-022561-rv5j1201	586	15	predecessor	predecessor	NN
cord-022561-rv5j1201	586	16	to	to	IN
cord-022561-rv5j1201	586	17	the	the	DT
cord-022561-rv5j1201	586	18	segmented	segmented	JJ
cord-022561-rv5j1201	586	19	neutrophil	neutrophil	NN
cord-022561-rv5j1201	586	20	normally	normally	RB
cord-022561-rv5j1201	586	21	found	find	VBN
cord-022561-rv5j1201	586	22	in	in	IN
cord-022561-rv5j1201	586	23	circulation	circulation	NN
cord-022561-rv5j1201	586	24	.	.	.
cord-022561-rv5j1201	587	1	Progressively	progressively	RB
cord-022561-rv5j1201	587	2	immature	immature	JJ
cord-022561-rv5j1201	587	3	predecessors	predecessor	NNS
cord-022561-rv5j1201	587	4	are	be	VBP
cord-022561-rv5j1201	587	5	seen	see	VBN
cord-022561-rv5j1201	587	6	with	with	IN
cord-022561-rv5j1201	587	7	increasingly	increasingly	RB
cord-022561-rv5j1201	587	8	severe	severe	JJ
cord-022561-rv5j1201	587	9	inflammation	inflammation	NN
cord-022561-rv5j1201	587	10	.	.	.
cord-022561-rv5j1201	588	1	A	a	DT
cord-022561-rv5j1201	588	2	left	left	JJ
cord-022561-rv5j1201	588	3	shift	shift	NN
cord-022561-rv5j1201	588	4	is	be	VBZ
cord-022561-rv5j1201	588	5	considered	consider	VBN
cord-022561-rv5j1201	588	6	orderly	orderly	JJ
cord-022561-rv5j1201	588	7	if	if	IN
cord-022561-rv5j1201	588	8	the	the	DT
cord-022561-rv5j1201	588	9	number	number	NN
cord-022561-rv5j1201	588	10	of	of	IN
cord-022561-rv5j1201	588	11	immature	immature	JJ
cord-022561-rv5j1201	588	12	neutrophils	neutrophil	NNS
cord-022561-rv5j1201	588	13	in	in	IN
cord-022561-rv5j1201	588	14	circulation	circulation	NN
cord-022561-rv5j1201	588	15	decreases	decrease	VBZ
cord-022561-rv5j1201	588	16	as	as	IN
cord-022561-rv5j1201	588	17	they	-PRON-	PRP
cord-022561-rv5j1201	588	18	become	become	VBP
cord-022561-rv5j1201	588	19	progressively	progressively	RB
cord-022561-rv5j1201	588	20	immature	immature	JJ
cord-022561-rv5j1201	588	21	.	.	.
cord-022561-rv5j1201	589	1	The	the	DT
cord-022561-rv5j1201	589	2	term	term	NN
cord-022561-rv5j1201	589	3	degenerative	degenerative	JJ
cord-022561-rv5j1201	589	4	left	left	JJ
cord-022561-rv5j1201	589	5	shift	shift	NN
cord-022561-rv5j1201	589	6	is	be	VBZ
cord-022561-rv5j1201	589	7	sometimes	sometimes	RB
cord-022561-rv5j1201	589	8	used	use	VBN
cord-022561-rv5j1201	589	9	to	to	TO
cord-022561-rv5j1201	589	10	describe	describe	VB
cord-022561-rv5j1201	589	11	cases	case	NNS
cord-022561-rv5j1201	589	12	in	in	IN
cord-022561-rv5j1201	589	13	which	which	WDT
cord-022561-rv5j1201	589	14	the	the	DT
cord-022561-rv5j1201	589	15	number	number	NN
cord-022561-rv5j1201	589	16	of	of	IN
cord-022561-rv5j1201	589	17	immature	immature	JJ
cord-022561-rv5j1201	589	18	forms	form	NNS
cord-022561-rv5j1201	589	19	exceeds	exceed	VBZ
cord-022561-rv5j1201	589	20	the	the	DT
cord-022561-rv5j1201	589	21	number	number	NN
cord-022561-rv5j1201	589	22	of	of	IN
cord-022561-rv5j1201	589	23	segmented	segmented	JJ
cord-022561-rv5j1201	589	24	neutrophils	neutrophil	NNS
cord-022561-rv5j1201	589	25	.	.	.
cord-022561-rv5j1201	590	1	As	as	IN
cord-022561-rv5j1201	590	2	with	with	IN
cord-022561-rv5j1201	590	3	glucocorticoidmediated	glucocorticoidmediated	NNP
cord-022561-rv5j1201	590	4	neutrophilia	neutrophilia	NNP
cord-022561-rv5j1201	590	5	,	,	,
cord-022561-rv5j1201	590	6	the	the	DT
cord-022561-rv5j1201	590	7	typical	typical	JJ
cord-022561-rv5j1201	590	8	magnitude	magnitude	NN
cord-022561-rv5j1201	590	9	of	of	IN
cord-022561-rv5j1201	590	10	neutrophilia	neutrophilia	NN
cord-022561-rv5j1201	590	11	caused	cause	VBN
cord-022561-rv5j1201	590	12	by	by	IN
cord-022561-rv5j1201	590	13	inflammation	inflammation	NN
cord-022561-rv5j1201	590	14	varies	varie	NNS
cord-022561-rv5j1201	590	15	by	by	IN
cord-022561-rv5j1201	590	16	species	specie	NNS
cord-022561-rv5j1201	590	17	,	,	,
cord-022561-rv5j1201	590	18	with	with	IN
cord-022561-rv5j1201	590	19	dogs	dog	NNS
cord-022561-rv5j1201	590	20	having	have	VBG
cord-022561-rv5j1201	590	21	the	the	DT
cord-022561-rv5j1201	590	22	most	most	RBS
cord-022561-rv5j1201	590	23	pronounced	pronounced	JJ
cord-022561-rv5j1201	590	24	response	response	NN
cord-022561-rv5j1201	590	25	.	.	.
cord-022561-rv5j1201	591	1	It	-PRON-	PRP
cord-022561-rv5j1201	591	2	might	may	MD
cord-022561-rv5j1201	591	3	be	be	VB
cord-022561-rv5j1201	591	4	useful	useful	JJ
cord-022561-rv5j1201	591	5	to	to	TO
cord-022561-rv5j1201	591	6	think	think	VB
cord-022561-rv5j1201	591	7	of	of	IN
cord-022561-rv5j1201	591	8	neutrophil	neutrophil	NN
cord-022561-rv5j1201	591	9	kinetics	kinetic	NNS
cord-022561-rv5j1201	591	10	in	in	IN
cord-022561-rv5j1201	591	11	terms	term	NNS
cord-022561-rv5j1201	591	12	of	of	IN
cord-022561-rv5j1201	591	13	a	a	DT
cord-022561-rv5j1201	591	14	producer	producer	NN
cord-022561-rv5j1201	591	15	-	-	HYPH
cord-022561-rv5j1201	591	16	consumer	consumer	NN
cord-022561-rv5j1201	591	17	model	model	NN
cord-022561-rv5j1201	591	18	in	in	IN
cord-022561-rv5j1201	591	19	which	which	WDT
cord-022561-rv5j1201	591	20	the	the	DT
cord-022561-rv5j1201	591	21	bone	bone	NN
cord-022561-rv5j1201	591	22	marrow	marrow	NN
cord-022561-rv5j1201	591	23	is	be	VBZ
cord-022561-rv5j1201	591	24	the	the	DT
cord-022561-rv5j1201	591	25	factory	factory	NN
cord-022561-rv5j1201	591	26	,	,	,
cord-022561-rv5j1201	591	27	and	and	CC
cord-022561-rv5j1201	591	28	the	the	DT
cord-022561-rv5j1201	591	29	tissues	tissue	NNS
cord-022561-rv5j1201	591	30	(	(	-LRB-
cord-022561-rv5j1201	591	31	where	where	WRB
cord-022561-rv5j1201	591	32	the	the	DT
cord-022561-rv5j1201	591	33	neutrophils	neutrophil	NNS
cord-022561-rv5j1201	591	34	eventually	eventually	RB
cord-022561-rv5j1201	591	35	go	go	VBP
cord-022561-rv5j1201	591	36	)	)	-RRB-
cord-022561-rv5j1201	591	37	are	be	VBP
cord-022561-rv5j1201	591	38	the	the	DT
cord-022561-rv5j1201	591	39	customers	customer	NNS
cord-022561-rv5j1201	591	40	.	.	.
cord-022561-rv5j1201	592	1	The	the	DT
cord-022561-rv5j1201	592	2	bone	bone	NN
cord-022561-rv5j1201	592	3	marrow	marrow	NN
cord-022561-rv5j1201	592	4	storage	storage	NN
cord-022561-rv5j1201	592	5	pool	pool	NN
cord-022561-rv5j1201	592	6	is	be	VBZ
cord-022561-rv5j1201	592	7	the	the	DT
cord-022561-rv5j1201	592	8	factory	factory	NN
cord-022561-rv5j1201	592	9	inventory	inventory	NN
cord-022561-rv5j1201	592	10	,	,	,
cord-022561-rv5j1201	592	11	and	and	CC
cord-022561-rv5j1201	592	12	the	the	DT
cord-022561-rv5j1201	592	13	neutrophils	neutrophil	NNS
cord-022561-rv5j1201	592	14	in	in	IN
cord-022561-rv5j1201	592	15	the	the	DT
cord-022561-rv5j1201	592	16	bloodstream	bloodstream	NN
cord-022561-rv5j1201	592	17	are	be	VBP
cord-022561-rv5j1201	592	18	in	in	IN
cord-022561-rv5j1201	592	19	delivery	delivery	NN
cord-022561-rv5j1201	592	20	to	to	IN
cord-022561-rv5j1201	592	21	the	the	DT
cord-022561-rv5j1201	592	22	customer	customer	NN
cord-022561-rv5j1201	592	23	.	.	.
cord-022561-rv5j1201	593	1	Within	within	IN
cord-022561-rv5j1201	593	2	the	the	DT
cord-022561-rv5j1201	593	3	blood	blood	NN
cord-022561-rv5j1201	593	4	vessels	vessel	NNS
cord-022561-rv5j1201	593	5	,	,	,
cord-022561-rv5j1201	593	6	circulating	circulate	VBG
cord-022561-rv5j1201	593	7	neutrophils	neutrophil	NNS
cord-022561-rv5j1201	593	8	are	be	VBP
cord-022561-rv5j1201	593	9	on	on	IN
cord-022561-rv5j1201	593	10	the	the	DT
cord-022561-rv5j1201	593	11	highway	highway	NN
cord-022561-rv5j1201	593	12	,	,	,
cord-022561-rv5j1201	593	13	and	and	CC
cord-022561-rv5j1201	593	14	marginating	marginate	VBG
cord-022561-rv5j1201	593	15	neutrophils	neutrophil	NNS
cord-022561-rv5j1201	593	16	are	be	VBP
cord-022561-rv5j1201	593	17	temporarily	temporarily	RB
cord-022561-rv5j1201	593	18	pulled	pull	VBN
cord-022561-rv5j1201	593	19	off	off	RP
cord-022561-rv5j1201	593	20	to	to	IN
cord-022561-rv5j1201	593	21	the	the	DT
cord-022561-rv5j1201	593	22	side	side	NN
cord-022561-rv5j1201	593	23	of	of	IN
cord-022561-rv5j1201	593	24	the	the	DT
cord-022561-rv5j1201	593	25	road	road	NN
cord-022561-rv5j1201	593	26	.	.	.
cord-022561-rv5j1201	594	1	During	during	IN
cord-022561-rv5j1201	594	2	health	health	NN
cord-022561-rv5j1201	594	3	,	,	,
cord-022561-rv5j1201	594	4	there	there	EX
cord-022561-rv5j1201	594	5	is	be	VBZ
cord-022561-rv5j1201	594	6	an	an	DT
cord-022561-rv5j1201	594	7	even	even	JJ
cord-022561-rv5j1201	594	8	flow	flow	NN
cord-022561-rv5j1201	594	9	of	of	IN
cord-022561-rv5j1201	594	10	neutrophils	neutrophil	NNS
cord-022561-rv5j1201	594	11	from	from	IN
cord-022561-rv5j1201	594	12	the	the	DT
cord-022561-rv5j1201	594	13	factory	factory	NN
cord-022561-rv5j1201	594	14	to	to	IN
cord-022561-rv5j1201	594	15	the	the	DT
cord-022561-rv5j1201	594	16	customer	customer	NN
cord-022561-rv5j1201	594	17	.	.	.
cord-022561-rv5j1201	595	1	Thus	thus	RB
cord-022561-rv5j1201	595	2	the	the	DT
cord-022561-rv5j1201	595	3	system	system	NN
cord-022561-rv5j1201	595	4	is	be	VBZ
cord-022561-rv5j1201	595	5	in	in	IN
cord-022561-rv5j1201	595	6	steady	steady	JJ
cord-022561-rv5j1201	595	7	state	state	NN
cord-022561-rv5j1201	595	8	,	,	,
cord-022561-rv5j1201	595	9	and	and	CC
cord-022561-rv5j1201	595	10	neutrophil	neutrophil	NN
cord-022561-rv5j1201	595	11	numbers	number	NNS
cord-022561-rv5j1201	595	12	remain	remain	VBP
cord-022561-rv5j1201	595	13	relatively	relatively	RB
cord-022561-rv5j1201	595	14	constant	constant	JJ
cord-022561-rv5j1201	595	15	and	and	CC
cord-022561-rv5j1201	595	16	within	within	IN
cord-022561-rv5j1201	595	17	the	the	DT
cord-022561-rv5j1201	595	18	normal	normal	JJ
cord-022561-rv5j1201	595	19	range	range	NN
cord-022561-rv5j1201	595	20	.	.	.
cord-022561-rv5j1201	596	1	However	however	RB
cord-022561-rv5j1201	596	2	,	,	,
cord-022561-rv5j1201	596	3	disease	disease	NN
cord-022561-rv5j1201	596	4	states	state	NNS
cord-022561-rv5j1201	596	5	may	may	MD
cord-022561-rv5j1201	596	6	perturb	perturb	VB
cord-022561-rv5j1201	596	7	this	this	DT
cord-022561-rv5j1201	596	8	system	system	NN
cord-022561-rv5j1201	596	9	at	at	IN
cord-022561-rv5j1201	596	10	multiple	multiple	JJ
cord-022561-rv5j1201	596	11	levels	level	NNS
cord-022561-rv5j1201	596	12	.	.	.
cord-022561-rv5j1201	597	1	Decreased	decrease	VBN
cord-022561-rv5j1201	597	2	granulopoiesis	granulopoiesis	NNP
cord-022561-rv5j1201	597	3	is	be	VBZ
cord-022561-rv5j1201	597	4	analogous	analogous	JJ
cord-022561-rv5j1201	597	5	to	to	IN
cord-022561-rv5j1201	597	6	a	a	DT
cord-022561-rv5j1201	597	7	factory	factory	NN
cord-022561-rv5j1201	597	8	working	work	VBG
cord-022561-rv5j1201	597	9	below	below	IN
cord-022561-rv5j1201	597	10	normal	normal	JJ
cord-022561-rv5j1201	597	11	production	production	NN
cord-022561-rv5j1201	597	12	level	level	NN
cord-022561-rv5j1201	597	13	.	.	.
cord-022561-rv5j1201	598	1	Ineffective	ineffective	JJ
cord-022561-rv5j1201	598	2	granulopoiesis	granulopoiesis	NN
cord-022561-rv5j1201	598	3	is	be	VBZ
cord-022561-rv5j1201	598	4	analogous	analogous	JJ
cord-022561-rv5j1201	598	5	to	to	IN
cord-022561-rv5j1201	598	6	goods	good	NNS
cord-022561-rv5j1201	598	7	that	that	WDT
cord-022561-rv5j1201	598	8	are	be	VBP
cord-022561-rv5j1201	598	9	produced	produce	VBN
cord-022561-rv5j1201	598	10	at	at	IN
cord-022561-rv5j1201	598	11	a	a	DT
cord-022561-rv5j1201	598	12	normal	normal	JJ
cord-022561-rv5j1201	598	13	to	to	IN
cord-022561-rv5j1201	598	14	increased	increase	VBN
cord-022561-rv5j1201	598	15	rate	rate	NN
cord-022561-rv5j1201	598	16	but	but	CC
cord-022561-rv5j1201	598	17	are	be	VBP
cord-022561-rv5j1201	598	18	damaged	damage	VBN
cord-022561-rv5j1201	598	19	during	during	IN
cord-022561-rv5j1201	598	20	manufacturing	manufacturing	NN
cord-022561-rv5j1201	598	21	and	and	CC
cord-022561-rv5j1201	598	22	never	never	RB
cord-022561-rv5j1201	598	23	leave	leave	VB
cord-022561-rv5j1201	598	24	the	the	DT
cord-022561-rv5j1201	598	25	factory	factory	NN
cord-022561-rv5j1201	598	26	.	.	.
cord-022561-rv5j1201	599	1	A	a	DT
cord-022561-rv5j1201	599	2	left	left	JJ
cord-022561-rv5j1201	599	3	shift	shift	NN
cord-022561-rv5j1201	599	4	is	be	VBZ
cord-022561-rv5j1201	599	5	analogous	analogous	JJ
cord-022561-rv5j1201	599	6	to	to	IN
cord-022561-rv5j1201	599	7	the	the	DT
cord-022561-rv5j1201	599	8	factory	factory	NN
cord-022561-rv5j1201	599	9	meeting	meeting	NN
cord-022561-rv5j1201	599	10	increased	increase	VBD
cord-022561-rv5j1201	599	11	customer	customer	NN
cord-022561-rv5j1201	599	12	demand	demand	NN
cord-022561-rv5j1201	599	13	by	by	IN
cord-022561-rv5j1201	599	14	shipping	ship	VBG
cord-022561-rv5j1201	599	15	out	out	RP
cord-022561-rv5j1201	599	16	unfinished	unfinished	JJ
cord-022561-rv5j1201	599	17	goods	good	NNS
cord-022561-rv5j1201	599	18	.	.	.
cord-022561-rv5j1201	600	1	Cases	case	NNS
cord-022561-rv5j1201	600	2	of	of	IN
cord-022561-rv5j1201	600	3	persistent	persistent	JJ
cord-022561-rv5j1201	600	4	,	,	,
cord-022561-rv5j1201	600	5	established	establish	VBN
cord-022561-rv5j1201	600	6	inflammation	inflammation	NN
cord-022561-rv5j1201	600	7	are	be	VBP
cord-022561-rv5j1201	600	8	characterized	characterize	VBN
cord-022561-rv5j1201	600	9	by	by	IN
cord-022561-rv5j1201	600	10	bone	bone	NN
cord-022561-rv5j1201	600	11	marrow	marrow	NN
cord-022561-rv5j1201	600	12	granulocytic	granulocytic	JJ
cord-022561-rv5j1201	600	13	hyperplasia	hyperplasia	NN
cord-022561-rv5j1201	600	14	and	and	CC
cord-022561-rv5j1201	600	15	mature	mature	VB
cord-022561-rv5j1201	600	16	neutrophilia	neutrophilia	NNS
cord-022561-rv5j1201	600	17	,	,	,
cord-022561-rv5j1201	600	18	analogous	analogous	JJ
cord-022561-rv5j1201	600	19	to	to	IN
cord-022561-rv5j1201	600	20	a	a	DT
cord-022561-rv5j1201	600	21	factory	factory	NN
cord-022561-rv5j1201	600	22	that	that	WDT
cord-022561-rv5j1201	600	23	has	have	VBZ
cord-022561-rv5j1201	600	24	had	have	VBN
cord-022561-rv5j1201	600	25	time	time	NN
cord-022561-rv5j1201	600	26	to	to	TO
cord-022561-rv5j1201	600	27	adjust	adjust	VB
cord-022561-rv5j1201	600	28	to	to	IN
cord-022561-rv5j1201	600	29	increased	increase	VBN
cord-022561-rv5j1201	600	30	demand	demand	NN
cord-022561-rv5j1201	600	31	and	and	CC
cord-022561-rv5j1201	600	32	is	be	VBZ
cord-022561-rv5j1201	600	33	meeting	meet	VBG
cord-022561-rv5j1201	600	34	it	-PRON-	PRP
cord-022561-rv5j1201	600	35	more	more	RBR
cord-022561-rv5j1201	600	36	efficiently	efficiently	RB
cord-022561-rv5j1201	600	37	by	by	IN
cord-022561-rv5j1201	600	38	increasing	increase	VBG
cord-022561-rv5j1201	600	39	its	-PRON-	PRP$
cord-022561-rv5j1201	600	40	output	output	NN
cord-022561-rv5j1201	600	41	.	.	.
cord-022561-rv5j1201	601	1	Eosinophilia	Eosinophilia	NNP
cord-022561-rv5j1201	601	2	/	/	SYM
cord-022561-rv5j1201	601	3	Basophilia	Basophilia	NNP
cord-022561-rv5j1201	601	4	.	.	.
cord-022561-rv5j1201	602	1	Eosinophilia	Eosinophilia	NNP
cord-022561-rv5j1201	602	2	and	and	CC
cord-022561-rv5j1201	602	3	basophilia	basophilia	NNP
cord-022561-rv5j1201	602	4	are	be	VBP
cord-022561-rv5j1201	602	5	increased	increase	VBN
cord-022561-rv5j1201	602	6	concentrations	concentration	NNS
cord-022561-rv5j1201	602	7	of	of	IN
cord-022561-rv5j1201	602	8	blood	blood	NN
cord-022561-rv5j1201	602	9	eosinophils	eosinophil	NNS
cord-022561-rv5j1201	602	10	and	and	CC
cord-022561-rv5j1201	602	11	basophils	basophil	NNS
cord-022561-rv5j1201	602	12	,	,	,
cord-022561-rv5j1201	602	13	respectively	respectively	RB
cord-022561-rv5j1201	602	14	.	.	.
cord-022561-rv5j1201	603	1	They	-PRON-	PRP
cord-022561-rv5j1201	603	2	may	may	MD
cord-022561-rv5j1201	603	3	occur	occur	VB
cord-022561-rv5j1201	603	4	with	with	IN
cord-022561-rv5j1201	603	5	parasitism	parasitism	NN
cord-022561-rv5j1201	603	6	,	,	,
cord-022561-rv5j1201	603	7	hypersensitivity	hypersensitivity	NN
cord-022561-rv5j1201	603	8	reactions	reaction	NNS
cord-022561-rv5j1201	603	9	,	,	,
cord-022561-rv5j1201	603	10	paraneoplastic	paraneoplastic	JJ
cord-022561-rv5j1201	603	11	responses	response	NNS
cord-022561-rv5j1201	603	12	(	(	-LRB-
cord-022561-rv5j1201	603	13	e.g.	e.g.	RB
cord-022561-rv5j1201	603	14	,	,	,
cord-022561-rv5j1201	603	15	lymphoma	lymphoma	NN
cord-022561-rv5j1201	603	16	,	,	,
cord-022561-rv5j1201	603	17	mast	mast	JJ
cord-022561-rv5j1201	603	18	cell	cell	NN
cord-022561-rv5j1201	603	19	neoplasia	neoplasia	NN
cord-022561-rv5j1201	603	20	,	,	,
cord-022561-rv5j1201	603	21	or	or	CC
cord-022561-rv5j1201	603	22	leukemia	leukemia	NN
cord-022561-rv5j1201	603	23	)	)	-RRB-
cord-022561-rv5j1201	603	24	,	,	,
cord-022561-rv5j1201	603	25	and	and	CC
cord-022561-rv5j1201	603	26	nonparasitic	nonparasitic	JJ
cord-022561-rv5j1201	603	27	infectious	infectious	JJ
cord-022561-rv5j1201	603	28	disease	disease	NN
cord-022561-rv5j1201	603	29	.	.	.
cord-022561-rv5j1201	604	1	Eosinophilia	Eosinophilia	NNP
cord-022561-rv5j1201	604	2	has	have	VBZ
cord-022561-rv5j1201	604	3	also	also	RB
cord-022561-rv5j1201	604	4	been	be	VBN
cord-022561-rv5j1201	604	5	documented	document	VBN
cord-022561-rv5j1201	604	6	with	with	IN
cord-022561-rv5j1201	604	7	hypoadrenocorticism	hypoadrenocorticism	NN
cord-022561-rv5j1201	604	8	and	and	CC
cord-022561-rv5j1201	604	9	rare	rare	JJ
cord-022561-rv5j1201	604	10	idiopathic	idiopathic	JJ
cord-022561-rv5j1201	604	11	conditions	condition	NNS
cord-022561-rv5j1201	604	12	(	(	-LRB-
cord-022561-rv5j1201	604	13	e.g.	e.g.	RB
cord-022561-rv5j1201	604	14	,	,	,
cord-022561-rv5j1201	604	15	hypereosinophilic	hypereosinophilic	NNP
cord-022561-rv5j1201	604	16	syndrome	syndrome	NN
cord-022561-rv5j1201	604	17	)	)	-RRB-
cord-022561-rv5j1201	604	18	.	.	.
cord-022561-rv5j1201	605	1	Most	Most	JJS
cord-022561-rv5j1201	605	2	cases	case	NNS
cord-022561-rv5j1201	605	3	of	of	IN
cord-022561-rv5j1201	605	4	eosinophilia	eosinophilia	NN
cord-022561-rv5j1201	605	5	and	and	CC
cord-022561-rv5j1201	605	6	basophilia	basophilia	NNP
cord-022561-rv5j1201	605	7	are	be	VBP
cord-022561-rv5j1201	605	8	due	due	JJ
cord-022561-rv5j1201	605	9	to	to	IN
cord-022561-rv5j1201	605	10	eosinophilic	eosinophilic	JJ
cord-022561-rv5j1201	605	11	and	and	CC
cord-022561-rv5j1201	605	12	basophilic	basophilic	JJ
cord-022561-rv5j1201	605	13	hyperplasia	hyperplasia	NN
cord-022561-rv5j1201	605	14	within	within	IN
cord-022561-rv5j1201	605	15	the	the	DT
cord-022561-rv5j1201	605	16	bone	bone	NN
cord-022561-rv5j1201	605	17	marrow	marrow	NN
cord-022561-rv5j1201	605	18	in	in	IN
cord-022561-rv5j1201	605	19	response	response	NN
cord-022561-rv5j1201	605	20	to	to	IN
cord-022561-rv5j1201	605	21	inflammatory	inflammatory	JJ
cord-022561-rv5j1201	605	22	growth	growth	NN
cord-022561-rv5j1201	605	23	factors	factor	NNS
cord-022561-rv5j1201	605	24	.	.	.
cord-022561-rv5j1201	606	1	However	however	RB
cord-022561-rv5j1201	606	2	,	,	,
cord-022561-rv5j1201	606	3	cortisol	cortisol	NN
cord-022561-rv5j1201	606	4	deficiency	deficiency	NN
cord-022561-rv5j1201	606	5	is	be	VBZ
cord-022561-rv5j1201	606	6	thought	think	VBN
cord-022561-rv5j1201	606	7	to	to	TO
cord-022561-rv5j1201	606	8	cause	cause	VB
cord-022561-rv5j1201	606	9	eosinophilia	eosinophilia	JJ
cord-022561-rv5j1201	606	10	in	in	IN
cord-022561-rv5j1201	606	11	dogs	dog	NNS
cord-022561-rv5j1201	606	12	with	with	IN
cord-022561-rv5j1201	606	13	hypoadrenocorticism	hypoadrenocorticism	NN
cord-022561-rv5j1201	606	14	.	.	.
cord-022561-rv5j1201	607	1	Monocytosis	Monocytosis	NNP
cord-022561-rv5j1201	607	2	.	.	.
cord-022561-rv5j1201	608	1	Monocytosis	Monocytosis	NNP
cord-022561-rv5j1201	608	2	is	be	VBZ
cord-022561-rv5j1201	608	3	an	an	DT
cord-022561-rv5j1201	608	4	increased	increase	VBN
cord-022561-rv5j1201	608	5	concentration	concentration	NN
cord-022561-rv5j1201	608	6	of	of	IN
cord-022561-rv5j1201	608	7	monocytes	monocyte	NNS
cord-022561-rv5j1201	608	8	in	in	IN
cord-022561-rv5j1201	608	9	blood	blood	NN
cord-022561-rv5j1201	608	10	.	.	.
cord-022561-rv5j1201	609	1	It	-PRON-	PRP
cord-022561-rv5j1201	609	2	most	most	RBS
cord-022561-rv5j1201	609	3	commonly	commonly	RB
cord-022561-rv5j1201	609	4	occurs	occur	VBZ
cord-022561-rv5j1201	609	5	with	with	IN
cord-022561-rv5j1201	609	6	excessive	excessive	JJ
cord-022561-rv5j1201	609	7	glucocorticoids	glucocorticoid	NNS
cord-022561-rv5j1201	609	8	or	or	CC
cord-022561-rv5j1201	609	9	inflammation	inflammation	NN
cord-022561-rv5j1201	609	10	and	and	CC
cord-022561-rv5j1201	609	11	uncommonly	uncommonly	RB
cord-022561-rv5j1201	609	12	to	to	TO
cord-022561-rv5j1201	609	13	rarely	rarely	RB
cord-022561-rv5j1201	609	14	with	with	IN
cord-022561-rv5j1201	609	15	monocytic	monocytic	JJ
cord-022561-rv5j1201	609	16	leukemia	leukemia	NN
cord-022561-rv5j1201	609	17	,	,	,
cord-022561-rv5j1201	609	18	immune	immune	NN
cord-022561-rv5j1201	609	19	-	-	HYPH
cord-022561-rv5j1201	609	20	mediated	mediate	VBN
cord-022561-rv5j1201	609	21	neutropenia	neutropenia	NN
cord-022561-rv5j1201	609	22	,	,	,
cord-022561-rv5j1201	609	23	and	and	CC
cord-022561-rv5j1201	609	24	cyclic	cyclic	JJ
cord-022561-rv5j1201	609	25	hematopoiesis	hematopoiesis	NN
cord-022561-rv5j1201	609	26	.	.	.
cord-022561-rv5j1201	610	1	With	with	IN
cord-022561-rv5j1201	610	2	excessive	excessive	JJ
cord-022561-rv5j1201	610	3	endogenous	endogenous	JJ
cord-022561-rv5j1201	610	4	or	or	CC
cord-022561-rv5j1201	610	5	exogenous	exogenous	JJ
cord-022561-rv5j1201	610	6	glucocorticoids	glucocorticoid	NNS
cord-022561-rv5j1201	610	7	,	,	,
cord-022561-rv5j1201	610	8	monocytes	monocyte	NNS
cord-022561-rv5j1201	610	9	shift	shift	NN
cord-022561-rv5j1201	610	10	from	from	IN
cord-022561-rv5j1201	610	11	the	the	DT
cord-022561-rv5j1201	610	12	marginating	marginating	NN
cord-022561-rv5j1201	610	13	pool	pool	NN
cord-022561-rv5j1201	610	14	to	to	IN
cord-022561-rv5j1201	610	15	the	the	DT
cord-022561-rv5j1201	610	16	circulating	circulate	VBG
cord-022561-rv5j1201	610	17	pool	pool	NN
cord-022561-rv5j1201	610	18	.	.	.
cord-022561-rv5j1201	611	1	This	this	DT
cord-022561-rv5j1201	611	2	stress	stress	NN
cord-022561-rv5j1201	611	3	monocytosis	monocytosis	NN
cord-022561-rv5j1201	611	4	is	be	VBZ
cord-022561-rv5j1201	611	5	most	most	RBS
cord-022561-rv5j1201	611	6	common	common	JJ
cord-022561-rv5j1201	611	7	in	in	IN
cord-022561-rv5j1201	611	8	dogs	dog	NNS
cord-022561-rv5j1201	611	9	,	,	,
cord-022561-rv5j1201	611	10	less	less	RBR
cord-022561-rv5j1201	611	11	frequent	frequent	JJ
cord-022561-rv5j1201	611	12	in	in	IN
cord-022561-rv5j1201	611	13	cats	cat	NNS
cord-022561-rv5j1201	611	14	,	,	,
cord-022561-rv5j1201	611	15	and	and	CC
cord-022561-rv5j1201	611	16	rare	rare	JJ
cord-022561-rv5j1201	611	17	in	in	IN
cord-022561-rv5j1201	611	18	horses	horse	NNS
cord-022561-rv5j1201	611	19	and	and	CC
cord-022561-rv5j1201	611	20	cattle	cattle	NNS
cord-022561-rv5j1201	611	21	.	.	.
cord-022561-rv5j1201	612	1	Inflammatory	inflammatory	JJ
cord-022561-rv5j1201	612	2	diseases	disease	NNS
cord-022561-rv5j1201	612	3	cause	cause	VBP
cord-022561-rv5j1201	612	4	monocytosis	monocytosis	NN
cord-022561-rv5j1201	612	5	by	by	IN
cord-022561-rv5j1201	612	6	cytokine	cytokine	NN
cord-022561-rv5j1201	612	7	-	-	HYPH
cord-022561-rv5j1201	612	8	mediated	mediate	VBN
cord-022561-rv5j1201	612	9	monocytic	monocytic	JJ
cord-022561-rv5j1201	612	10	hyperplasia	hyperplasia	NN
cord-022561-rv5j1201	612	11	in	in	IN
cord-022561-rv5j1201	612	12	the	the	DT
cord-022561-rv5j1201	612	13	bone	bone	NN
cord-022561-rv5j1201	612	14	marrow	marrow	NN
cord-022561-rv5j1201	612	15	.	.	.
cord-022561-rv5j1201	613	1	causes	cause	NNS
cord-022561-rv5j1201	613	2	of	of	IN
cord-022561-rv5j1201	613	3	neutrophilia	neutrophilia	NNP
cord-022561-rv5j1201	613	4	:	:	:
cord-022561-rv5j1201	613	5	glucocorticoid	glucocorticoid	NN
cord-022561-rv5j1201	613	6	excess	excess	NN
cord-022561-rv5j1201	613	7	and	and	CC
cord-022561-rv5j1201	613	8	epinephrine	epinephrine	NN
cord-022561-rv5j1201	613	9	excess	excess	NN
cord-022561-rv5j1201	613	10	.	.	.
cord-022561-rv5j1201	614	1	Less	less	RBR
cord-022561-rv5j1201	614	2	common	common	JJ
cord-022561-rv5j1201	614	3	causes	cause	NNS
cord-022561-rv5j1201	614	4	of	of	IN
cord-022561-rv5j1201	614	5	neutrophilia	neutrophilia	NNP
cord-022561-rv5j1201	614	6	,	,	,
cord-022561-rv5j1201	614	7	such	such	JJ
cord-022561-rv5j1201	614	8	as	as	IN
cord-022561-rv5j1201	614	9	leukocyte	leukocyte	NN
cord-022561-rv5j1201	614	10	adhesion	adhesion	NN
cord-022561-rv5j1201	614	11	deficiency	deficiency	NN
cord-022561-rv5j1201	614	12	and	and	CC
cord-022561-rv5j1201	614	13	neoplasia	neoplasia	NN
cord-022561-rv5j1201	614	14	,	,	,
cord-022561-rv5j1201	614	15	are	be	VBP
cord-022561-rv5j1201	614	16	discussed	discuss	VBN
cord-022561-rv5j1201	614	17	later	later	RB
cord-022561-rv5j1201	614	18	in	in	IN
cord-022561-rv5j1201	614	19	the	the	DT
cord-022561-rv5j1201	614	20	chapter	chapter	NN
cord-022561-rv5j1201	614	21	.	.	.
cord-022561-rv5j1201	615	1	Glucocorticoid	glucocorticoid	JJ
cord-022561-rv5j1201	615	2	excess	excess	NN
cord-022561-rv5j1201	615	3	,	,	,
cord-022561-rv5j1201	615	4	either	either	CC
cord-022561-rv5j1201	615	5	because	because	IN
cord-022561-rv5j1201	615	6	of	of	IN
cord-022561-rv5j1201	615	7	endogenous	endogenous	JJ
cord-022561-rv5j1201	615	8	production	production	NN
cord-022561-rv5j1201	615	9	or	or	CC
cord-022561-rv5j1201	615	10	exogenous	exogenous	JJ
cord-022561-rv5j1201	615	11	administration	administration	NN
cord-022561-rv5j1201	615	12	,	,	,
cord-022561-rv5j1201	615	13	results	result	VBZ
cord-022561-rv5j1201	615	14	in	in	IN
cord-022561-rv5j1201	615	15	a	a	DT
cord-022561-rv5j1201	615	16	CBC	CBC	NNP
cord-022561-rv5j1201	615	17	pattern	pattern	NN
cord-022561-rv5j1201	615	18	known	know	VBN
cord-022561-rv5j1201	615	19	as	as	IN
cord-022561-rv5j1201	615	20	the	the	DT
cord-022561-rv5j1201	615	21	stress	stress	NN
cord-022561-rv5j1201	615	22	leukogram	leukogram	NNP
cord-022561-rv5j1201	615	23	,	,	,
cord-022561-rv5j1201	615	24	characterized	characterize	VBN
cord-022561-rv5j1201	615	25	by	by	IN
cord-022561-rv5j1201	615	26	mature	mature	JJ
cord-022561-rv5j1201	615	27	neutrophilia	neutrophilia	NNS
cord-022561-rv5j1201	615	28	(	(	-LRB-
cord-022561-rv5j1201	615	29	i.e.	i.e.	FW
cord-022561-rv5j1201	615	30	,	,	,
cord-022561-rv5j1201	615	31	increased	increase	VBN
cord-022561-rv5j1201	615	32	concentration	concentration	NN
cord-022561-rv5j1201	615	33	of	of	IN
cord-022561-rv5j1201	615	34	segmented	segmented	JJ
cord-022561-rv5j1201	615	35	neutrophils	neutrophil	NNS
cord-022561-rv5j1201	615	36	without	without	IN
cord-022561-rv5j1201	615	37	immature	immature	JJ
cord-022561-rv5j1201	615	38	neutrophils	neutrophil	NNS
cord-022561-rv5j1201	615	39	)	)	-RRB-
cord-022561-rv5j1201	615	40	and	and	CC
cord-022561-rv5j1201	615	41	lymphopenia	lymphopenia	NNP
cord-022561-rv5j1201	615	42	,	,	,
cord-022561-rv5j1201	615	43	with	with	IN
cord-022561-rv5j1201	615	44	or	or	CC
cord-022561-rv5j1201	615	45	without	without	IN
cord-022561-rv5j1201	615	46	monocytosis	monocytosis	NNP
cord-022561-rv5j1201	615	47	and	and	CC
cord-022561-rv5j1201	615	48	eosinopenia	eosinopenia	NNP
cord-022561-rv5j1201	615	49	.	.	.
cord-022561-rv5j1201	616	1	Mechanisms	mechanism	NNS
cord-022561-rv5j1201	616	2	contributing	contribute	VBG
cord-022561-rv5j1201	616	3	to	to	IN
cord-022561-rv5j1201	616	4	glucocorticoid	glucocorticoid	NN
cord-022561-rv5j1201	616	5	-	-	HYPH
cord-022561-rv5j1201	616	6	mediated	mediate	VBN
cord-022561-rv5j1201	616	7	neutrophilia	neutrophilia	NNS
cord-022561-rv5j1201	616	8	include	include	VBP
cord-022561-rv5j1201	616	9	the	the	DT
cord-022561-rv5j1201	616	10	following	follow	VBG
cord-022561-rv5j1201	616	11	:	:	:
cord-022561-rv5j1201	616	12	•	•	XX
cord-022561-rv5j1201	617	1	Increased	increase	VBN
cord-022561-rv5j1201	617	2	release	release	NN
cord-022561-rv5j1201	617	3	of	of	IN
cord-022561-rv5j1201	617	4	mature	mature	JJ
cord-022561-rv5j1201	617	5	neutrophils	neutrophil	NNS
cord-022561-rv5j1201	617	6	from	from	IN
cord-022561-rv5j1201	617	7	the	the	DT
cord-022561-rv5j1201	617	8	bone	bone	NN
cord-022561-rv5j1201	617	9	marrow	marrow	NN
cord-022561-rv5j1201	617	10	storage	storage	NN
cord-022561-rv5j1201	617	11	pool	pool	NN
cord-022561-rv5j1201	618	1	•	•	NNP
cord-022561-rv5j1201	619	1	Decreased	decrease	VBN
cord-022561-rv5j1201	619	2	margination	margination	NN
cord-022561-rv5j1201	619	3	of	of	IN
cord-022561-rv5j1201	619	4	neutrophils	neutrophil	NNS
cord-022561-rv5j1201	619	5	within	within	IN
cord-022561-rv5j1201	619	6	the	the	DT
cord-022561-rv5j1201	619	7	vasculature	vasculature	NN
cord-022561-rv5j1201	619	8	,	,	,
cord-022561-rv5j1201	619	9	with	with	IN
cord-022561-rv5j1201	619	10	a	a	DT
cord-022561-rv5j1201	619	11	resulting	result	VBG
cord-022561-rv5j1201	619	12	increase	increase	NN
cord-022561-rv5j1201	619	13	in	in	IN
cord-022561-rv5j1201	619	14	the	the	DT
cord-022561-rv5j1201	619	15	circulating	circulate	VBG
cord-022561-rv5j1201	619	16	pool	pool	NN
cord-022561-rv5j1201	620	1	•	•	NNP
cord-022561-rv5j1201	621	1	Decreased	decrease	VBN
cord-022561-rv5j1201	621	2	migration	migration	NN
cord-022561-rv5j1201	621	3	of	of	IN
cord-022561-rv5j1201	621	4	neutrophils	neutrophil	NNS
cord-022561-rv5j1201	621	5	from	from	IN
cord-022561-rv5j1201	621	6	the	the	DT
cord-022561-rv5j1201	621	7	bloodstream	bloodstream	NN
cord-022561-rv5j1201	621	8	into	into	IN
cord-022561-rv5j1201	621	9	tissues	tissue	NNS
cord-022561-rv5j1201	622	1	The	the	DT
cord-022561-rv5j1201	622	2	magnitude	magnitude	NN
cord-022561-rv5j1201	622	3	of	of	IN
cord-022561-rv5j1201	622	4	neutrophilia	neutrophilia	NNP
cord-022561-rv5j1201	622	5	tends	tend	VBZ
cord-022561-rv5j1201	622	6	to	to	TO
cord-022561-rv5j1201	622	7	be	be	VB
cord-022561-rv5j1201	622	8	species	specie	NNS
cord-022561-rv5j1201	622	9	dependent	dependent	JJ
cord-022561-rv5j1201	622	10	,	,	,
cord-022561-rv5j1201	622	11	with	with	IN
cord-022561-rv5j1201	622	12	dogs	dog	NNS
cord-022561-rv5j1201	622	13	having	have	VBG
cord-022561-rv5j1201	622	14	the	the	DT
cord-022561-rv5j1201	622	15	most	most	RBS
cord-022561-rv5j1201	622	16	pronounced	pronounced	JJ
cord-022561-rv5j1201	622	17	response	response	NN
cord-022561-rv5j1201	622	18	(	(	-LRB-
cord-022561-rv5j1201	622	19	up	up	IN
cord-022561-rv5j1201	622	20	to	to	IN
cord-022561-rv5j1201	622	21	35,000	35,000	CD
cord-022561-rv5j1201	622	22	cells/µL	cells/µL	NNP
cord-022561-rv5j1201	622	23	)	)	-RRB-
cord-022561-rv5j1201	622	24	and	and	CC
cord-022561-rv5j1201	623	1	in	in	IN
cord-022561-rv5j1201	623	2	decreasing	decrease	VBG
cord-022561-rv5j1201	623	3	order	order	NN
cord-022561-rv5j1201	623	4	of	of	IN
cord-022561-rv5j1201	623	5	responsiveness	responsiveness	NN
cord-022561-rv5j1201	623	6	,	,	,
cord-022561-rv5j1201	623	7	cats	cat	NNS
cord-022561-rv5j1201	623	8	(	(	-LRB-
cord-022561-rv5j1201	623	9	30,000	30,000	CD
cord-022561-rv5j1201	623	10	cells/µL	cells/µL	NNP
cord-022561-rv5j1201	623	11	)	)	-RRB-
cord-022561-rv5j1201	623	12	,	,	,
cord-022561-rv5j1201	623	13	horses	horse	NNS
cord-022561-rv5j1201	623	14	(	(	-LRB-
cord-022561-rv5j1201	623	15	20,000	20,000	CD
cord-022561-rv5j1201	623	16	cells/µL	cells/µL	NNP
cord-022561-rv5j1201	623	17	)	)	-RRB-
cord-022561-rv5j1201	623	18	,	,	,
cord-022561-rv5j1201	623	19	and	and	CC
cord-022561-rv5j1201	623	20	cattle	cattle	NNS
cord-022561-rv5j1201	623	21	(	(	-LRB-
cord-022561-rv5j1201	623	22	15,000	15,000	CD
cord-022561-rv5j1201	623	23	cells/µL	cells/µL	NNP
cord-022561-rv5j1201	623	24	)	)	-RRB-
cord-022561-rv5j1201	623	25	having	have	VBG
cord-022561-rv5j1201	623	26	less	less	RBR
cord-022561-rv5j1201	623	27	marked	marked	JJ
cord-022561-rv5j1201	623	28	responses	response	NNS
cord-022561-rv5j1201	623	29	.	.	.
cord-022561-rv5j1201	624	1	With	with	IN
cord-022561-rv5j1201	624	2	long	long	JJ
cord-022561-rv5j1201	624	3	-	-	HYPH
cord-022561-rv5j1201	624	4	term	term	NN
cord-022561-rv5j1201	624	5	glucocorticoid	glucocorticoid	NN
cord-022561-rv5j1201	624	6	excess	excess	NN
cord-022561-rv5j1201	624	7	,	,	,
cord-022561-rv5j1201	624	8	neutrophil	neutrophil	NN
cord-022561-rv5j1201	624	9	numbers	number	NNS
cord-022561-rv5j1201	624	10	tend	tend	VBP
cord-022561-rv5j1201	624	11	to	to	TO
cord-022561-rv5j1201	624	12	normalize	normalize	VB
cord-022561-rv5j1201	624	13	,	,	,
cord-022561-rv5j1201	624	14	whereas	whereas	IN
cord-022561-rv5j1201	624	15	lymphopenia	lymphopenia	NNP
cord-022561-rv5j1201	624	16	persists	persist	VBZ
cord-022561-rv5j1201	624	17	.	.	.
cord-022561-rv5j1201	625	1	Epinephrine	epinephrine	NN
cord-022561-rv5j1201	625	2	release	release	NN
cord-022561-rv5j1201	625	3	results	result	NNS
cord-022561-rv5j1201	625	4	in	in	IN
cord-022561-rv5j1201	625	5	a	a	DT
cord-022561-rv5j1201	625	6	different	different	JJ
cord-022561-rv5j1201	625	7	pattern	pattern	NN
cord-022561-rv5j1201	625	8	,	,	,
cord-022561-rv5j1201	625	9	known	know	VBN
cord-022561-rv5j1201	625	10	as	as	IN
cord-022561-rv5j1201	625	11	physiologic	physiologic	JJ
cord-022561-rv5j1201	625	12	leukocytosis	leukocytosis	NN
cord-022561-rv5j1201	625	13	or	or	CC
cord-022561-rv5j1201	625	14	excitement	excitement	NN
cord-022561-rv5j1201	625	15	leukocytosis	leukocytosis	NNP
cord-022561-rv5j1201	625	16	,	,	,
cord-022561-rv5j1201	625	17	characterized	characterize	VBN
cord-022561-rv5j1201	625	18	by	by	IN
cord-022561-rv5j1201	625	19	mature	mature	JJ
cord-022561-rv5j1201	625	20	neutrophilia	neutrophilia	NNP
cord-022561-rv5j1201	625	21	(	(	-LRB-
cord-022561-rv5j1201	625	22	like	like	IN
cord-022561-rv5j1201	625	23	the	the	DT
cord-022561-rv5j1201	625	24	glucocorticoid	glucocorticoid	NN
cord-022561-rv5j1201	625	25	response	response	NN
cord-022561-rv5j1201	625	26	)	)	-RRB-
cord-022561-rv5j1201	625	27	and	and	CC
cord-022561-rv5j1201	625	28	lymphocytosis	lymphocytosis	NNP
cord-022561-rv5j1201	625	29	(	(	-LRB-
cord-022561-rv5j1201	625	30	unlike	unlike	IN
cord-022561-rv5j1201	625	31	the	the	DT
cord-022561-rv5j1201	625	32	glucocorticoid	glucocorticoid	NN
cord-022561-rv5j1201	625	33	response	response	NN
cord-022561-rv5j1201	625	34	)	)	-RRB-
cord-022561-rv5j1201	625	35	.	.	.
cord-022561-rv5j1201	626	1	This	this	DT
cord-022561-rv5j1201	626	2	phenomenon	phenomenon	NN
cord-022561-rv5j1201	626	3	is	be	VBZ
cord-022561-rv5j1201	626	4	short	short	JJ
cord-022561-rv5j1201	626	5	lived	live	VBN
cord-022561-rv5j1201	626	6	(	(	-LRB-
cord-022561-rv5j1201	626	7	i.e.	i.e.	FW
cord-022561-rv5j1201	626	8	,	,	,
cord-022561-rv5j1201	626	9	<	<	XX
cord-022561-rv5j1201	626	10	1	1	CD
cord-022561-rv5j1201	626	11	hour	hour	NN
cord-022561-rv5j1201	626	12	)	)	-RRB-
cord-022561-rv5j1201	626	13	.	.	.
cord-022561-rv5j1201	627	1	Neutrophilia	Neutrophilia	NNP
cord-022561-rv5j1201	627	2	occurs	occur	VBZ
cord-022561-rv5j1201	627	3	primarily	primarily	RB
cord-022561-rv5j1201	627	4	because	because	IN
cord-022561-rv5j1201	627	5	of	of	IN
cord-022561-rv5j1201	627	6	a	a	DT
cord-022561-rv5j1201	627	7	shift	shift	NN
cord-022561-rv5j1201	627	8	of	of	IN
cord-022561-rv5j1201	627	9	cells	cell	NNS
cord-022561-rv5j1201	627	10	from	from	IN
cord-022561-rv5j1201	627	11	the	the	DT
cord-022561-rv5j1201	627	12	marginating	marginating	NN
cord-022561-rv5j1201	627	13	to	to	IN
cord-022561-rv5j1201	627	14	the	the	DT
cord-022561-rv5j1201	627	15	circulating	circulate	VBG
cord-022561-rv5j1201	627	16	pool	pool	NN
cord-022561-rv5j1201	627	17	.	.	.
cord-022561-rv5j1201	628	1	Physiologic	physiologic	JJ
cord-022561-rv5j1201	628	2	leukocytosis	leukocytosis	NN
cord-022561-rv5j1201	628	3	is	be	VBZ
cord-022561-rv5j1201	628	4	common	common	JJ
cord-022561-rv5j1201	628	5	in	in	IN
cord-022561-rv5j1201	628	6	cats	cat	NNS
cord-022561-rv5j1201	628	7	(	(	-LRB-
cord-022561-rv5j1201	628	8	especially	especially	RB
cord-022561-rv5j1201	628	9	when	when	WRB
cord-022561-rv5j1201	628	10	they	-PRON-	PRP
cord-022561-rv5j1201	628	11	are	be	VBP
cord-022561-rv5j1201	628	12	highly	highly	RB
cord-022561-rv5j1201	628	13	stressed	stress	VBN
cord-022561-rv5j1201	628	14	during	during	IN
cord-022561-rv5j1201	628	15	blood	blood	NN
cord-022561-rv5j1201	628	16	collection	collection	NN
cord-022561-rv5j1201	628	17	)	)	-RRB-
cord-022561-rv5j1201	628	18	and	and	CC
cord-022561-rv5j1201	628	19	horses	horse	NNS
cord-022561-rv5j1201	628	20	,	,	,
cord-022561-rv5j1201	628	21	less	less	RBR
cord-022561-rv5j1201	628	22	common	common	JJ
cord-022561-rv5j1201	628	23	in	in	IN
cord-022561-rv5j1201	628	24	cattle	cattle	NNS
cord-022561-rv5j1201	628	25	,	,	,
cord-022561-rv5j1201	628	26	and	and	CC
cord-022561-rv5j1201	628	27	uncommon	uncommon	JJ
cord-022561-rv5j1201	628	28	in	in	IN
cord-022561-rv5j1201	628	29	dogs	dog	NNS
cord-022561-rv5j1201	628	30	.	.	.
cord-022561-rv5j1201	629	1	of	of	IN
cord-022561-rv5j1201	629	2	a	a	DT
cord-022561-rv5j1201	629	3	regenerative	regenerative	JJ
cord-022561-rv5j1201	629	4	response	response	NN
cord-022561-rv5j1201	629	5	in	in	IN
cord-022561-rv5j1201	629	6	patients	patient	NNS
cord-022561-rv5j1201	629	7	recovering	recover	VBG
cord-022561-rv5j1201	629	8	from	from	IN
cord-022561-rv5j1201	629	9	thrombocytopenia	thrombocytopenia	NN
cord-022561-rv5j1201	629	10	,	,	,
cord-022561-rv5j1201	629	11	as	as	IN
cord-022561-rv5j1201	629	12	a	a	DT
cord-022561-rv5j1201	629	13	result	result	NN
cord-022561-rv5j1201	629	14	of	of	IN
cord-022561-rv5j1201	629	15	redistribution	redistribution	NN
cord-022561-rv5j1201	629	16	after	after	IN
cord-022561-rv5j1201	629	17	splenic	splenic	JJ
cord-022561-rv5j1201	629	18	contraction	contraction	NN
cord-022561-rv5j1201	629	19	,	,	,
cord-022561-rv5j1201	629	20	or	or	CC
cord-022561-rv5j1201	629	21	within	within	IN
cord-022561-rv5j1201	629	22	the	the	DT
cord-022561-rv5j1201	629	23	several	several	JJ
cord-022561-rv5j1201	629	24	weeks	week	NNS
cord-022561-rv5j1201	629	25	after	after	IN
cord-022561-rv5j1201	629	26	splenectomy	splenectomy	NN
cord-022561-rv5j1201	629	27	.	.	.
cord-022561-rv5j1201	630	1	In	in	IN
cord-022561-rv5j1201	630	2	these	these	DT
cord-022561-rv5j1201	630	3	cases	case	NNS
cord-022561-rv5j1201	630	4	,	,	,
cord-022561-rv5j1201	630	5	thrombocytosis	thrombocytosis	NNP
cord-022561-rv5j1201	630	6	is	be	VBZ
cord-022561-rv5j1201	630	7	transient	transient	JJ
cord-022561-rv5j1201	630	8	.	.	.
cord-022561-rv5j1201	631	1	In	in	IN
cord-022561-rv5j1201	631	2	the	the	DT
cord-022561-rv5j1201	631	3	case	case	NN
cord-022561-rv5j1201	631	4	of	of	IN
cord-022561-rv5j1201	631	5	splenectomy	splenectomy	NN
cord-022561-rv5j1201	631	6	,	,	,
cord-022561-rv5j1201	631	7	thrombocytosis	thrombocytosis	NNP
cord-022561-rv5j1201	631	8	may	may	MD
cord-022561-rv5j1201	631	9	be	be	VB
cord-022561-rv5j1201	631	10	marked	mark	VBN
cord-022561-rv5j1201	631	11	but	but	CC
cord-022561-rv5j1201	631	12	normalizes	normalize	VBZ
cord-022561-rv5j1201	631	13	after	after	IN
cord-022561-rv5j1201	631	14	several	several	JJ
cord-022561-rv5j1201	631	15	weeks	week	NNS
cord-022561-rv5j1201	631	16	.	.	.
cord-022561-rv5j1201	632	1	Because	because	IN
cord-022561-rv5j1201	632	2	the	the	DT
cord-022561-rv5j1201	632	3	body	body	NN
cord-022561-rv5j1201	632	4	's	's	POS
cord-022561-rv5j1201	632	5	total	total	JJ
cord-022561-rv5j1201	632	6	platelet	platelet	NN
cord-022561-rv5j1201	632	7	mass	mass	NN
cord-022561-rv5j1201	632	8	regulates	regulate	VBZ
cord-022561-rv5j1201	632	9	thrombopoiesis	thrombopoiesis	NNP
cord-022561-rv5j1201	632	10	,	,	,
cord-022561-rv5j1201	632	11	and	and	CC
cord-022561-rv5j1201	632	12	a	a	DT
cord-022561-rv5j1201	632	13	significant	significant	JJ
cord-022561-rv5j1201	632	14	portion	portion	NN
cord-022561-rv5j1201	632	15	of	of	IN
cord-022561-rv5j1201	632	16	the	the	DT
cord-022561-rv5j1201	632	17	platelet	platelet	NN
cord-022561-rv5j1201	632	18	mass	mass	NN
cord-022561-rv5j1201	632	19	is	be	VBZ
cord-022561-rv5j1201	632	20	normally	normally	RB
cord-022561-rv5j1201	632	21	in	in	IN
cord-022561-rv5j1201	632	22	the	the	DT
cord-022561-rv5j1201	632	23	spleen	spleen	NN
cord-022561-rv5j1201	632	24	,	,	,
cord-022561-rv5j1201	632	25	it	-PRON-	PRP
cord-022561-rv5j1201	632	26	makes	make	VBZ
cord-022561-rv5j1201	632	27	sense	sense	NN
cord-022561-rv5j1201	632	28	that	that	IN
cord-022561-rv5j1201	632	29	splenectomized	splenectomize	VBN
cord-022561-rv5j1201	632	30	animals	animal	NNS
cord-022561-rv5j1201	632	31	develop	develop	VBP
cord-022561-rv5j1201	632	32	thrombocytosis	thrombocytosis	NN
cord-022561-rv5j1201	632	33	.	.	.
cord-022561-rv5j1201	633	1	However	however	RB
cord-022561-rv5j1201	633	2	,	,	,
cord-022561-rv5j1201	633	3	the	the	DT
cord-022561-rv5j1201	633	4	reason	reason	NN
cord-022561-rv5j1201	633	5	that	that	IN
cord-022561-rv5j1201	633	6	the	the	DT
cord-022561-rv5j1201	633	7	number	number	NN
cord-022561-rv5j1201	633	8	of	of	IN
cord-022561-rv5j1201	633	9	circulating	circulate	VBG
cord-022561-rv5j1201	633	10	platelets	platelet	NNS
cord-022561-rv5j1201	633	11	normalizes	normalize	VBZ
cord-022561-rv5j1201	633	12	in	in	IN
cord-022561-rv5j1201	633	13	these	these	DT
cord-022561-rv5j1201	633	14	individuals	individual	NNS
cord-022561-rv5j1201	633	15	in	in	IN
cord-022561-rv5j1201	633	16	the	the	DT
cord-022561-rv5j1201	633	17	weeks	week	NNS
cord-022561-rv5j1201	633	18	after	after	IN
cord-022561-rv5j1201	633	19	splenectomy	splenectomy	NN
cord-022561-rv5j1201	633	20	is	be	VBZ
cord-022561-rv5j1201	633	21	not	not	RB
cord-022561-rv5j1201	633	22	Thrombocytosis	Thrombocytosis	NNP
cord-022561-rv5j1201	633	23	.	.	.
cord-022561-rv5j1201	634	1	Thrombocytosis	Thrombocytosis	NNP
cord-022561-rv5j1201	634	2	,	,	,
cord-022561-rv5j1201	634	3	or	or	CC
cord-022561-rv5j1201	634	4	an	an	DT
cord-022561-rv5j1201	634	5	increased	increase	VBN
cord-022561-rv5j1201	634	6	concentration	concentration	NN
cord-022561-rv5j1201	634	7	of	of	IN
cord-022561-rv5j1201	634	8	platelets	platelet	NNS
cord-022561-rv5j1201	634	9	in	in	IN
cord-022561-rv5j1201	634	10	the	the	DT
cord-022561-rv5j1201	634	11	blood	blood	NN
cord-022561-rv5j1201	634	12	,	,	,
cord-022561-rv5j1201	634	13	is	be	VBZ
cord-022561-rv5j1201	634	14	a	a	DT
cord-022561-rv5j1201	634	15	relatively	relatively	RB
cord-022561-rv5j1201	634	16	common	common	JJ
cord-022561-rv5j1201	634	17	,	,	,
cord-022561-rv5j1201	634	18	nonspecific	nonspecific	JJ
cord-022561-rv5j1201	634	19	finding	finding	NN
cord-022561-rv5j1201	634	20	in	in	IN
cord-022561-rv5j1201	634	21	veterinary	veterinary	JJ
cord-022561-rv5j1201	634	22	patients	patient	NNS
cord-022561-rv5j1201	634	23	.	.	.
cord-022561-rv5j1201	635	1	In	in	IN
cord-022561-rv5j1201	635	2	the	the	DT
cord-022561-rv5j1201	635	3	vast	vast	JJ
cord-022561-rv5j1201	635	4	majority	majority	NN
cord-022561-rv5j1201	635	5	of	of	IN
cord-022561-rv5j1201	635	6	cases	case	NNS
cord-022561-rv5j1201	635	7	,	,	,
cord-022561-rv5j1201	635	8	thrombocytosis	thrombocytosis	NNP
cord-022561-rv5j1201	635	9	is	be	VBZ
cord-022561-rv5j1201	635	10	reactive	reactive	JJ
cord-022561-rv5j1201	635	11	-	-	:
cord-022561-rv5j1201	635	12	a	a	DT
cord-022561-rv5j1201	635	13	response	response	NN
cord-022561-rv5j1201	635	14	to	to	IN
cord-022561-rv5j1201	635	15	another	another	DT
cord-022561-rv5j1201	635	16	,	,	,
cord-022561-rv5j1201	635	17	often	often	RB
cord-022561-rv5j1201	635	18	apparently	apparently	RB
cord-022561-rv5j1201	635	19	unrelated	unrelated	JJ
cord-022561-rv5j1201	635	20	,	,	,
cord-022561-rv5j1201	635	21	disease	disease	NN
cord-022561-rv5j1201	635	22	process	process	NN
cord-022561-rv5j1201	635	23	.	.	.
cord-022561-rv5j1201	636	1	Examples	example	NNS
cord-022561-rv5j1201	636	2	of	of	IN
cord-022561-rv5j1201	636	3	conditions	condition	NNS
cord-022561-rv5j1201	636	4	having	have	VBG
cord-022561-rv5j1201	636	5	reactive	reactive	JJ
cord-022561-rv5j1201	636	6	thrombocytosis	thrombocytosis	NN
cord-022561-rv5j1201	636	7	include	include	VBP
cord-022561-rv5j1201	636	8	inflammatory	inflammatory	JJ
cord-022561-rv5j1201	636	9	and	and	CC
cord-022561-rv5j1201	636	10	infectious	infectious	JJ
cord-022561-rv5j1201	636	11	diseases	disease	NNS
cord-022561-rv5j1201	636	12	,	,	,
cord-022561-rv5j1201	636	13	iron	iron	NN
cord-022561-rv5j1201	636	14	deficiency	deficiency	NN
cord-022561-rv5j1201	636	15	,	,	,
cord-022561-rv5j1201	636	16	hemorrhage	hemorrhage	NN
cord-022561-rv5j1201	636	17	,	,	,
cord-022561-rv5j1201	636	18	endocrinopathies	endocrinopathie	NNS
cord-022561-rv5j1201	636	19	,	,	,
cord-022561-rv5j1201	636	20	and	and	CC
cord-022561-rv5j1201	636	21	neoplasia	neoplasia	NN
cord-022561-rv5j1201	636	22	.	.	.
cord-022561-rv5j1201	637	1	Factors	factor	NNS
cord-022561-rv5j1201	637	2	that	that	WDT
cord-022561-rv5j1201	637	3	may	may	MD
cord-022561-rv5j1201	637	4	contribute	contribute	VB
cord-022561-rv5j1201	637	5	to	to	IN
cord-022561-rv5j1201	637	6	reactive	reactive	JJ
cord-022561-rv5j1201	637	7	thrombocytosis	thrombocytosis	NN
cord-022561-rv5j1201	637	8	include	include	VBP
cord-022561-rv5j1201	637	9	increased	increase	VBN
cord-022561-rv5j1201	637	10	plasma	plasma	NN
cord-022561-rv5j1201	637	11	concentration	concentration	NN
cord-022561-rv5j1201	637	12	of	of	IN
cord-022561-rv5j1201	637	13	thrombopoietin	thrombopoietin	NNP
cord-022561-rv5j1201	637	14	,	,	,
cord-022561-rv5j1201	637	15	inflammatory	inflammatory	JJ
cord-022561-rv5j1201	637	16	cytokines	cytokine	NNS
cord-022561-rv5j1201	637	17	(	(	-LRB-
cord-022561-rv5j1201	637	18	e.g.	e.g.	RB
cord-022561-rv5j1201	637	19	,	,	,
cord-022561-rv5j1201	637	20	IL-6	IL-6	NNP
cord-022561-rv5j1201	637	21	)	)	-RRB-
cord-022561-rv5j1201	637	22	,	,	,
cord-022561-rv5j1201	637	23	or	or	CC
cord-022561-rv5j1201	637	24	catecholamines	catecholamine	NNS
cord-022561-rv5j1201	637	25	.	.	.
cord-022561-rv5j1201	638	1	Thrombocytosis	Thrombocytosis	NNP
cord-022561-rv5j1201	638	2	may	may	MD
cord-022561-rv5j1201	638	3	also	also	RB
cord-022561-rv5j1201	638	4	occur	occur	VB
cord-022561-rv5j1201	638	5	as	as	IN
cord-022561-rv5j1201	638	6	part	part	NN
cord-022561-rv5j1201	638	7	1	1	CD
cord-022561-rv5j1201	638	8	,	,	,
cord-022561-rv5j1201	638	9	Neutrophils	Neutrophils	NNPS
cord-022561-rv5j1201	638	10	and	and	CC
cord-022561-rv5j1201	638	11	their	-PRON-	PRP$
cord-022561-rv5j1201	638	12	precursors	precursor	NNS
cord-022561-rv5j1201	638	13	are	be	VBP
cord-022561-rv5j1201	638	14	distributed	distribute	VBN
cord-022561-rv5j1201	638	15	in	in	IN
cord-022561-rv5j1201	638	16	five	five	CD
cord-022561-rv5j1201	638	17	pools	pool	NNS
cord-022561-rv5j1201	638	18	:	:	:
cord-022561-rv5j1201	638	19	a	a	DT
cord-022561-rv5j1201	638	20	bone	bone	NN
cord-022561-rv5j1201	638	21	marrow	marrow	NN
cord-022561-rv5j1201	638	22	precursor	precursor	NN
cord-022561-rv5j1201	638	23	pool	pool	NN
cord-022561-rv5j1201	638	24	,	,	,
cord-022561-rv5j1201	638	25	which	which	WDT
cord-022561-rv5j1201	638	26	includes	include	VBZ
cord-022561-rv5j1201	638	27	mitotically	mitotically	RB
cord-022561-rv5j1201	638	28	active	active	JJ
cord-022561-rv5j1201	638	29	and	and	CC
cord-022561-rv5j1201	638	30	inactive	inactive	JJ
cord-022561-rv5j1201	638	31	immature	immature	JJ
cord-022561-rv5j1201	638	32	cells	cell	NNS
cord-022561-rv5j1201	638	33	;	;	:
cord-022561-rv5j1201	638	34	a	a	DT
cord-022561-rv5j1201	638	35	bone	bone	NN
cord-022561-rv5j1201	638	36	marrow	marrow	NN
cord-022561-rv5j1201	638	37	storage	storage	NN
cord-022561-rv5j1201	638	38	pool	pool	NN
cord-022561-rv5j1201	638	39	,	,	,
cord-022561-rv5j1201	638	40	consisting	consist	VBG
cord-022561-rv5j1201	638	41	of	of	IN
cord-022561-rv5j1201	638	42	mitotically	mitotically	RB
cord-022561-rv5j1201	638	43	inactive	inactive	JJ
cord-022561-rv5j1201	638	44	mature	mature	JJ
cord-022561-rv5j1201	638	45	neutrophils	neutrophil	NNS
cord-022561-rv5j1201	638	46	;	;	:
cord-022561-rv5j1201	638	47	a	a	DT
cord-022561-rv5j1201	638	48	peripheral	peripheral	JJ
cord-022561-rv5j1201	638	49	blood	blood	NN
cord-022561-rv5j1201	638	50	marginating	marginate	VBG
cord-022561-rv5j1201	638	51	pool	pool	NN
cord-022561-rv5j1201	638	52	;	;	:
cord-022561-rv5j1201	638	53	a	a	DT
cord-022561-rv5j1201	638	54	peripheral	peripheral	JJ
cord-022561-rv5j1201	638	55	blood	blood	NN
cord-022561-rv5j1201	638	56	circulating	circulate	VBG
cord-022561-rv5j1201	638	57	pool	pool	NN
cord-022561-rv5j1201	638	58	;	;	:
cord-022561-rv5j1201	638	59	and	and	CC
cord-022561-rv5j1201	638	60	a	a	DT
cord-022561-rv5j1201	638	61	tissue	tissue	NN
cord-022561-rv5j1201	638	62	pool	pool	NN
cord-022561-rv5j1201	638	63	.	.	.
cord-022561-rv5j1201	639	1	The	the	DT
cord-022561-rv5j1201	639	2	relative	relative	JJ
cord-022561-rv5j1201	639	3	size	size	NN
cord-022561-rv5j1201	639	4	of	of	IN
cord-022561-rv5j1201	639	5	each	each	DT
cord-022561-rv5j1201	639	6	pool	pool	NN
cord-022561-rv5j1201	639	7	is	be	VBZ
cord-022561-rv5j1201	639	8	represented	represent	VBN
cord-022561-rv5j1201	639	9	by	by	IN
cord-022561-rv5j1201	639	10	the	the	DT
cord-022561-rv5j1201	639	11	size	size	NN
cord-022561-rv5j1201	639	12	of	of	IN
cord-022561-rv5j1201	639	13	its	-PRON-	PRP$
cord-022561-rv5j1201	639	14	corresponding	correspond	VBG
cord-022561-rv5j1201	639	15	wedge	wedge	NN
cord-022561-rv5j1201	639	16	.	.	.
cord-022561-rv5j1201	640	1	The	the	DT
cord-022561-rv5j1201	640	2	peripheral	peripheral	JJ
cord-022561-rv5j1201	640	3	blood	blood	NN
cord-022561-rv5j1201	640	4	neutrophil	neutrophil	NN
cord-022561-rv5j1201	640	5	count	count	NN
cord-022561-rv5j1201	640	6	measures	measure	NNS
cord-022561-rv5j1201	640	7	only	only	RB
cord-022561-rv5j1201	640	8	neutrophils	neutrophil	NNS
cord-022561-rv5j1201	640	9	within	within	IN
cord-022561-rv5j1201	640	10	the	the	DT
cord-022561-rv5j1201	640	11	circulating	circulate	VBG
cord-022561-rv5j1201	640	12	peripheral	peripheral	JJ
cord-022561-rv5j1201	640	13	blood	blood	NN
cord-022561-rv5j1201	640	14	pool	pool	NN
cord-022561-rv5j1201	640	15	,	,	,
cord-022561-rv5j1201	640	16	which	which	WDT
cord-022561-rv5j1201	640	17	can	can	MD
cord-022561-rv5j1201	640	18	be	be	VB
cord-022561-rv5j1201	640	19	enlarged	enlarge	VBN
cord-022561-rv5j1201	640	20	by	by	IN
cord-022561-rv5j1201	640	21	(	(	-LRB-
cord-022561-rv5j1201	640	22	2	2	CD
cord-022561-rv5j1201	640	23	)	)	-RRB-
cord-022561-rv5j1201	640	24	increased	increase	VBN
cord-022561-rv5j1201	640	25	demargination	demargination	NN
cord-022561-rv5j1201	640	26	,	,	,
cord-022561-rv5j1201	640	27	(	(	-LRB-
cord-022561-rv5j1201	640	28	3	3	LS
cord-022561-rv5j1201	640	29	)	)	-RRB-
cord-022561-rv5j1201	640	30	diminished	diminish	VBD
cord-022561-rv5j1201	640	31	extravasation	extravasation	NN
cord-022561-rv5j1201	640	32	into	into	IN
cord-022561-rv5j1201	640	33	tissue	tissue	NN
cord-022561-rv5j1201	640	34	,	,	,
cord-022561-rv5j1201	640	35	(	(	-LRB-
cord-022561-rv5j1201	640	36	4	4	LS
cord-022561-rv5j1201	640	37	)	)	-RRB-
cord-022561-rv5j1201	640	38	increased	increase	VBN
cord-022561-rv5j1201	640	39	release	release	NN
cord-022561-rv5j1201	640	40	of	of	IN
cord-022561-rv5j1201	640	41	cells	cell	NNS
cord-022561-rv5j1201	640	42	from	from	IN
cord-022561-rv5j1201	640	43	the	the	DT
cord-022561-rv5j1201	640	44	marrow	marrow	NN
cord-022561-rv5j1201	640	45	storage	storage	NN
cord-022561-rv5j1201	640	46	pool	pool	NN
cord-022561-rv5j1201	640	47	,	,	,
cord-022561-rv5j1201	640	48	and	and	CC
cord-022561-rv5j1201	640	49	(	(	-LRB-
cord-022561-rv5j1201	640	50	5	5	LS
cord-022561-rv5j1201	640	51	)	)	-RRB-
cord-022561-rv5j1201	640	52	 	 	_SP
cord-022561-rv5j1201	640	53	Cells	cell	NNS
cord-022561-rv5j1201	640	54	.	.	.
cord-022561-rv5j1201	641	1	The	the	DT
cord-022561-rv5j1201	641	2	preceding	precede	VBG
cord-022561-rv5j1201	641	3	section	section	NN
cord-022561-rv5j1201	641	4	focused	focus	VBN
cord-022561-rv5j1201	641	5	on	on	IN
cord-022561-rv5j1201	641	6	abnormalities	abnormality	NNS
cord-022561-rv5j1201	641	7	in	in	IN
cord-022561-rv5j1201	641	8	the	the	DT
cord-022561-rv5j1201	641	9	number	number	NN
cord-022561-rv5j1201	641	10	of	of	IN
cord-022561-rv5j1201	641	11	blood	blood	NN
cord-022561-rv5j1201	641	12	cells	cell	NNS
cord-022561-rv5j1201	641	13	.	.	.
cord-022561-rv5j1201	642	1	There	there	EX
cord-022561-rv5j1201	642	2	are	be	VBP
cord-022561-rv5j1201	642	3	also	also	RB
cord-022561-rv5j1201	642	4	various	various	JJ
cord-022561-rv5j1201	642	5	acquired	acquire	VBN
cord-022561-rv5j1201	642	6	and	and	CC
cord-022561-rv5j1201	642	7	congenital	congenital	JJ
cord-022561-rv5j1201	642	8	conditions	condition	NNS
cord-022561-rv5j1201	642	9	involving	involve	VBG
cord-022561-rv5j1201	642	10	abnormal	abnormal	JJ
cord-022561-rv5j1201	642	11	structure	structure	NN
cord-022561-rv5j1201	642	12	or	or	CC
cord-022561-rv5j1201	642	13	function	function	NN
cord-022561-rv5j1201	642	14	of	of	IN
cord-022561-rv5j1201	642	15	blood	blood	NN
cord-022561-rv5j1201	642	16	cells	cell	NNS
cord-022561-rv5j1201	642	17	.	.	.
cord-022561-rv5j1201	643	1	This	this	DT
cord-022561-rv5j1201	643	2	section	section	NN
cord-022561-rv5j1201	643	3	briefly	briefly	RB
cord-022561-rv5j1201	643	4	discusses	discuss	VBZ
cord-022561-rv5j1201	643	5	abnormal	abnormal	JJ
cord-022561-rv5j1201	643	6	blood	blood	NN
cord-022561-rv5j1201	643	7	cell	cell	NN
cord-022561-rv5j1201	643	8	structure	structure	NN
cord-022561-rv5j1201	643	9	or	or	CC
cord-022561-rv5j1201	643	10	function	function	NN
cord-022561-rv5j1201	643	11	occurring	occur	VBG
cord-022561-rv5j1201	643	12	secondary	secondary	JJ
cord-022561-rv5j1201	643	13	to	to	IN
cord-022561-rv5j1201	643	14	other	other	JJ
cord-022561-rv5j1201	643	15	underlying	underlie	VBG
cord-022561-rv5j1201	643	16	disease	disease	NN
cord-022561-rv5j1201	643	17	.	.	.
cord-022561-rv5j1201	644	1	Primary	primary	JJ
cord-022561-rv5j1201	644	2	disorders	disorder	NNS
cord-022561-rv5j1201	644	3	of	of	IN
cord-022561-rv5j1201	644	4	blood	blood	NN
cord-022561-rv5j1201	644	5	cells	cell	NNS
cord-022561-rv5j1201	644	6	are	be	VBP
cord-022561-rv5j1201	644	7	discussed	discuss	VBN
cord-022561-rv5j1201	644	8	later	later	RB
cord-022561-rv5j1201	644	9	in	in	IN
cord-022561-rv5j1201	644	10	the	the	DT
cord-022561-rv5j1201	644	11	chapter	chapter	NN
cord-022561-rv5j1201	644	12	in	in	IN
cord-022561-rv5j1201	644	13	the	the	DT
cord-022561-rv5j1201	644	14	section	section	NN
cord-022561-rv5j1201	644	15	on	on	IN
cord-022561-rv5j1201	644	16	specific	specific	JJ
cord-022561-rv5j1201	644	17	diseases	disease	NNS
cord-022561-rv5j1201	644	18	.	.	.
cord-022561-rv5j1201	645	1	Morphologic	morphologic	JJ
cord-022561-rv5j1201	645	2	abnormalities	abnormality	NNS
cord-022561-rv5j1201	645	3	detected	detect	VBN
cord-022561-rv5j1201	645	4	on	on	IN
cord-022561-rv5j1201	645	5	routine	routine	JJ
cord-022561-rv5j1201	645	6	microscopic	microscopic	JJ
cord-022561-rv5j1201	645	7	examination	examination	NN
cord-022561-rv5j1201	645	8	of	of	IN
cord-022561-rv5j1201	645	9	blood	blood	NN
cord-022561-rv5j1201	645	10	smears	smear	NNS
cord-022561-rv5j1201	645	11	may	may	MD
cord-022561-rv5j1201	645	12	provide	provide	VB
cord-022561-rv5j1201	645	13	important	important	JJ
cord-022561-rv5j1201	645	14	clues	clue	NNS
cord-022561-rv5j1201	645	15	about	about	IN
cord-022561-rv5j1201	645	16	underlying	underlie	VBG
cord-022561-rv5j1201	645	17	disease	disease	NN
cord-022561-rv5j1201	645	18	processes	process	NNS
cord-022561-rv5j1201	645	19	.	.	.
cord-022561-rv5j1201	646	1	Poikilocytosis	Poikilocytosis	NNP
cord-022561-rv5j1201	646	2	is	be	VBZ
cord-022561-rv5j1201	646	3	a	a	DT
cord-022561-rv5j1201	646	4	broad	broad	JJ
cord-022561-rv5j1201	646	5	term	term	NN
cord-022561-rv5j1201	646	6	referring	refer	VBG
cord-022561-rv5j1201	646	7	to	to	IN
cord-022561-rv5j1201	646	8	the	the	DT
cord-022561-rv5j1201	646	9	presence	presence	NN
cord-022561-rv5j1201	646	10	of	of	IN
cord-022561-rv5j1201	646	11	abnormally	abnormally	RB
cord-022561-rv5j1201	646	12	shaped	shape	VBN
cord-022561-rv5j1201	646	13	erythrocytes	erythrocyte	NNS
cord-022561-rv5j1201	646	14	in	in	IN
cord-022561-rv5j1201	646	15	circulation	circulation	NN
cord-022561-rv5j1201	646	16	.	.	.
cord-022561-rv5j1201	647	1	E-	E-	NNP
cord-022561-rv5j1201	647	2	Table	Table	NNP
cord-022561-rv5j1201	647	3	13	13	CD
cord-022561-rv5j1201	647	4	-1	-1	NN
cord-022561-rv5j1201	647	5	lists	list	NNS
cord-022561-rv5j1201	647	6	conditions	condition	NNS
cord-022561-rv5j1201	647	7	with	with	IN
cord-022561-rv5j1201	647	8	and	and	CC
cord-022561-rv5j1201	647	9	mechanisms	mechanism	NNS
cord-022561-rv5j1201	647	10	involved	involve	VBN
cord-022561-rv5j1201	647	11	in	in	IN
cord-022561-rv5j1201	647	12	the	the	DT
cord-022561-rv5j1201	647	13	formation	formation	NN
cord-022561-rv5j1201	647	14	of	of	IN
cord-022561-rv5j1201	647	15	a	a	DT
cord-022561-rv5j1201	647	16	number	number	NN
cord-022561-rv5j1201	647	17	of	of	IN
cord-022561-rv5j1201	647	18	specific	specific	JJ
cord-022561-rv5j1201	647	19	types	type	NNS
cord-022561-rv5j1201	647	20	of	of	IN
cord-022561-rv5j1201	647	21	erythrocyte	erythrocyte	NN
cord-022561-rv5j1201	647	22	morphologic	morphologic	JJ
cord-022561-rv5j1201	647	23	abnormalities	abnormality	NNS
cord-022561-rv5j1201	647	24	,	,	,
cord-022561-rv5j1201	647	25	and	and	CC
cord-022561-rv5j1201	647	26	Fig	Fig	NNP
cord-022561-rv5j1201	647	27	.	.	NNP
cord-022561-rv5j1201	647	28	13	13	CD
cord-022561-rv5j1201	647	29	-	-	SYM
cord-022561-rv5j1201	647	30	15	15	CD
cord-022561-rv5j1201	647	31	shows	show	NNS
cord-022561-rv5j1201	647	32	some	some	DT
cord-022561-rv5j1201	647	33	examples	example	NNS
cord-022561-rv5j1201	647	34	.	.	.
cord-022561-rv5j1201	648	1	The	the	DT
cord-022561-rv5j1201	648	2	acquired	acquire	VBN
cord-022561-rv5j1201	648	3	neutrophil	neutrophil	NN
cord-022561-rv5j1201	648	4	morphologic	morphologic	JJ
cord-022561-rv5j1201	648	5	abnormality	abnormality	NN
cord-022561-rv5j1201	648	6	known	know	VBN
cord-022561-rv5j1201	648	7	as	as	IN
cord-022561-rv5j1201	648	8	toxic	toxic	JJ
cord-022561-rv5j1201	648	9	change	change	NN
cord-022561-rv5j1201	649	1	(	(	-LRB-
cord-022561-rv5j1201	649	2	Fig	Fig	NNP
cord-022561-rv5j1201	649	3	.	.	NNP
cord-022561-rv5j1201	649	4	13	13	CD
cord-022561-rv5j1201	649	5	-20	-20	CD
cord-022561-rv5j1201	649	6	)	)	-RRB-
cord-022561-rv5j1201	649	7	reflects	reflect	VBZ
cord-022561-rv5j1201	649	8	accelerated	accelerated	JJ
cord-022561-rv5j1201	649	9	production	production	NN
cord-022561-rv5j1201	649	10	of	of	IN
cord-022561-rv5j1201	649	11	neutrophils	neutrophil	NNS
cord-022561-rv5j1201	649	12	as	as	IN
cord-022561-rv5j1201	649	13	part	part	NN
cord-022561-rv5j1201	649	14	of	of	IN
cord-022561-rv5j1201	649	15	the	the	DT
cord-022561-rv5j1201	649	16	inflammatory	inflammatory	JJ
cord-022561-rv5j1201	649	17	response	response	NN
cord-022561-rv5j1201	649	18	.	.	.
cord-022561-rv5j1201	650	1	Features	feature	NNS
cord-022561-rv5j1201	650	2	of	of	IN
cord-022561-rv5j1201	650	3	toxic	toxic	JJ
cord-022561-rv5j1201	650	4	change	change	NN
cord-022561-rv5j1201	650	5	include	include	VBP
cord-022561-rv5j1201	650	6	increased	increase	VBN
cord-022561-rv5j1201	650	7	cytoplasmic	cytoplasmic	JJ
cord-022561-rv5j1201	650	8	basophilia	basophilia	NN
cord-022561-rv5j1201	650	9	,	,	,
cord-022561-rv5j1201	650	10	the	the	DT
cord-022561-rv5j1201	650	11	presence	presence	NN
cord-022561-rv5j1201	650	12	of	of	IN
cord-022561-rv5j1201	650	13	small	small	JJ
cord-022561-rv5j1201	650	14	bluegray	bluegray	JJ
cord-022561-rv5j1201	650	15	cytoplasmic	cytoplasmic	JJ
cord-022561-rv5j1201	650	16	inclusions	inclusion	NNS
cord-022561-rv5j1201	650	17	known	know	VBN
cord-022561-rv5j1201	650	18	as	as	IN
cord-022561-rv5j1201	650	19	Döhle	Döhle	NNP
cord-022561-rv5j1201	650	20	bodies	body	NNS
cord-022561-rv5j1201	650	21	(	(	-LRB-
cord-022561-rv5j1201	650	22	often	often	RB
cord-022561-rv5j1201	650	23	noted	note	VBN
cord-022561-rv5j1201	650	24	incidentally	incidentally	RB
cord-022561-rv5j1201	650	25	in	in	IN
cord-022561-rv5j1201	650	26	cats	cat	NNS
cord-022561-rv5j1201	650	27	)	)	-RRB-
cord-022561-rv5j1201	650	28	,	,	,
cord-022561-rv5j1201	650	29	and	and	CC
cord-022561-rv5j1201	650	30	in	in	IN
cord-022561-rv5j1201	650	31	more	more	RBR
cord-022561-rv5j1201	650	32	severe	severe	JJ
cord-022561-rv5j1201	650	33	cases	case	NNS
cord-022561-rv5j1201	650	34	,	,	,
cord-022561-rv5j1201	650	35	cytoplasmic	cytoplasmic	JJ
cord-022561-rv5j1201	650	36	vacuolation	vacuolation	NN
cord-022561-rv5j1201	650	37	.	.	.
cord-022561-rv5j1201	651	1	Although	although	IN
cord-022561-rv5j1201	651	2	not	not	RB
cord-022561-rv5j1201	651	3	causing	cause	VBG
cord-022561-rv5j1201	651	4	impaired	impaired	JJ
cord-022561-rv5j1201	651	5	neutrophil	neutrophil	NN
cord-022561-rv5j1201	651	6	function	function	NN
cord-022561-rv5j1201	651	7	,	,	,
cord-022561-rv5j1201	651	8	toxic	toxic	JJ
cord-022561-rv5j1201	651	9	change	change	NN
cord-022561-rv5j1201	651	10	occurs	occur	VBZ
cord-022561-rv5j1201	651	11	during	during	IN
cord-022561-rv5j1201	651	12	granulopoiesis	granulopoiesis	NNP
cord-022561-rv5j1201	651	13	and	and	CC
cord-022561-rv5j1201	651	14	thus	thus	RB
cord-022561-rv5j1201	651	15	is	be	VBZ
cord-022561-rv5j1201	651	16	technically	technically	RB
cord-022561-rv5j1201	651	17	a	a	DT
cord-022561-rv5j1201	651	18	form	form	NN
cord-022561-rv5j1201	651	19	of	of	IN
cord-022561-rv5j1201	651	20	dysplasia	dysplasia	NN
cord-022561-rv5j1201	651	21	(	(	-LRB-
cord-022561-rv5j1201	651	22	e.g.	e.g.	RB
cord-022561-rv5j1201	651	23	,	,	,
cord-022561-rv5j1201	651	24	Döhle	Döhle	NNP
cord-022561-rv5j1201	651	25	bodies	body	NNS
cord-022561-rv5j1201	651	26	are	be	VBP
cord-022561-rv5j1201	651	27	foci	foci	JJ
cord-022561-rv5j1201	651	28	of	of	IN
cord-022561-rv5j1201	651	29	aggregated	aggregated	JJ
cord-022561-rv5j1201	651	30	endoplasmic	endoplasmic	NN
cord-022561-rv5j1201	651	31	reticulum	reticulum	NN
cord-022561-rv5j1201	651	32	)	)	-RRB-
cord-022561-rv5j1201	651	33	.	.	.
cord-022561-rv5j1201	652	1	Toxic	toxic	JJ
cord-022561-rv5j1201	652	2	change	change	NN
cord-022561-rv5j1201	652	3	may	may	MD
cord-022561-rv5j1201	652	4	accompany	accompany	VB
cord-022561-rv5j1201	652	5	any	any	DT
cord-022561-rv5j1201	652	6	inflammatory	inflammatory	JJ
cord-022561-rv5j1201	652	7	response	response	NN
cord-022561-rv5j1201	652	8	,	,	,
cord-022561-rv5j1201	652	9	but	but	CC
cord-022561-rv5j1201	652	10	in	in	IN
cord-022561-rv5j1201	652	11	general	general	JJ
cord-022561-rv5j1201	652	12	the	the	DT
cord-022561-rv5j1201	652	13	more	more	RBR
cord-022561-rv5j1201	652	14	marked	mark	VBD
cord-022561-rv5j1201	652	15	the	the	DT
cord-022561-rv5j1201	652	16	toxic	toxic	JJ
cord-022561-rv5j1201	652	17	change	change	NN
cord-022561-rv5j1201	652	18	,	,	,
cord-022561-rv5j1201	652	19	the	the	DT
cord-022561-rv5j1201	652	20	higher	high	JJR
cord-022561-rv5j1201	652	21	the	the	DT
cord-022561-rv5j1201	652	22	index	index	NN
cord-022561-rv5j1201	652	23	of	of	IN
cord-022561-rv5j1201	652	24	suspicion	suspicion	NN
cord-022561-rv5j1201	652	25	for	for	IN
cord-022561-rv5j1201	652	26	infection	infection	NN
cord-022561-rv5j1201	652	27	or	or	CC
cord-022561-rv5j1201	652	28	endotoxemia	endotoxemia	NN
cord-022561-rv5j1201	652	29	.	.	.
cord-022561-rv5j1201	653	1	Other	other	JJ
cord-022561-rv5j1201	653	2	secondary	secondary	JJ
cord-022561-rv5j1201	653	3	changes	change	NNS
cord-022561-rv5j1201	653	4	to	to	IN
cord-022561-rv5j1201	653	5	neutrophils	neutrophil	NNS
cord-022561-rv5j1201	653	6	may	may	MD
cord-022561-rv5j1201	653	7	not	not	RB
cord-022561-rv5j1201	653	8	be	be	VB
cord-022561-rv5j1201	653	9	evident	evident	JJ
cord-022561-rv5j1201	653	10	morphologically	morphologically	RB
cord-022561-rv5j1201	653	11	.	.	.
cord-022561-rv5j1201	654	1	For	for	IN
cord-022561-rv5j1201	654	2	example	example	NN
cord-022561-rv5j1201	654	3	,	,	,
cord-022561-rv5j1201	654	4	studies	study	NNS
cord-022561-rv5j1201	654	5	in	in	IN
cord-022561-rv5j1201	654	6	human	human	JJ
cord-022561-rv5j1201	654	7	beings	being	NNS
cord-022561-rv5j1201	654	8	and	and	CC
cord-022561-rv5j1201	654	9	dogs	dog	NNS
cord-022561-rv5j1201	654	10	have	have	VBP
cord-022561-rv5j1201	654	11	shown	show	VBN
cord-022561-rv5j1201	654	12	that	that	IN
cord-022561-rv5j1201	654	13	individuals	individual	NNS
cord-022561-rv5j1201	654	14	with	with	IN
cord-022561-rv5j1201	654	15	cancer	cancer	NN
cord-022561-rv5j1201	654	16	have	have	VBP
cord-022561-rv5j1201	654	17	abnormal	abnormal	JJ
cord-022561-rv5j1201	654	18	neutrophil	neutrophil	NN
cord-022561-rv5j1201	654	19	function	function	NN
cord-022561-rv5j1201	654	20	(	(	-LRB-
cord-022561-rv5j1201	654	21	including	include	VBG
cord-022561-rv5j1201	654	22	phagocytic	phagocytic	JJ
cord-022561-rv5j1201	654	23	activity	activity	NN
cord-022561-rv5j1201	654	24	,	,	,
cord-022561-rv5j1201	654	25	killing	kill	VBG
cord-022561-rv5j1201	654	26	capacity	capacity	NN
cord-022561-rv5j1201	654	27	,	,	,
cord-022561-rv5j1201	654	28	and	and	CC
cord-022561-rv5j1201	654	29	oxidative	oxidative	JJ
cord-022561-rv5j1201	654	30	burst	burst	NN
cord-022561-rv5j1201	654	31	activity	activity	NN
cord-022561-rv5j1201	654	32	)	)	-RRB-
cord-022561-rv5j1201	654	33	before	before	IN
cord-022561-rv5j1201	654	34	initiation	initiation	NN
cord-022561-rv5j1201	654	35	of	of	IN
cord-022561-rv5j1201	654	36	therapy	therapy	NN
cord-022561-rv5j1201	654	37	.	.	.
cord-022561-rv5j1201	655	1	The	the	DT
cord-022561-rv5j1201	655	2	clinical	clinical	JJ
cord-022561-rv5j1201	655	3	significance	significance	NN
cord-022561-rv5j1201	655	4	of	of	IN
cord-022561-rv5j1201	655	5	this	this	DT
cord-022561-rv5j1201	655	6	finding	finding	NN
cord-022561-rv5j1201	655	7	is	be	VBZ
cord-022561-rv5j1201	655	8	not	not	RB
cord-022561-rv5j1201	655	9	clear	clear	JJ
cord-022561-rv5j1201	655	10	.	.	.
cord-022561-rv5j1201	656	1	Platelet	platelet	NN
cord-022561-rv5j1201	656	2	function	function	NN
cord-022561-rv5j1201	656	3	disorders	disorder	NNS
cord-022561-rv5j1201	656	4	,	,	,
cord-022561-rv5j1201	656	5	also	also	RB
cord-022561-rv5j1201	656	6	known	know	VBN
cord-022561-rv5j1201	656	7	as	as	IN
cord-022561-rv5j1201	656	8	thrombopathies	thrombopathie	NNS
cord-022561-rv5j1201	656	9	or	or	CC
cord-022561-rv5j1201	656	10	thrombopathias	thrombopathias	NNP
cord-022561-rv5j1201	656	11	,	,	,
cord-022561-rv5j1201	656	12	may	may	MD
cord-022561-rv5j1201	656	13	be	be	VB
cord-022561-rv5j1201	656	14	primary	primary	JJ
cord-022561-rv5j1201	656	15	or	or	CC
cord-022561-rv5j1201	656	16	secondary	secondary	JJ
cord-022561-rv5j1201	656	17	.	.	.
cord-022561-rv5j1201	657	1	Many	many	JJ
cord-022561-rv5j1201	657	2	conditions	condition	NNS
cord-022561-rv5j1201	657	3	are	be	VBP
cord-022561-rv5j1201	657	4	known	know	VBN
cord-022561-rv5j1201	657	5	or	or	CC
cord-022561-rv5j1201	657	6	suspected	suspect	VBN
cord-022561-rv5j1201	657	7	to	to	TO
cord-022561-rv5j1201	657	8	cause	cause	VB
cord-022561-rv5j1201	657	9	secondary	secondary	JJ
cord-022561-rv5j1201	657	10	platelet	platelet	NN
cord-022561-rv5j1201	657	11	dysfunction	dysfunction	NN
cord-022561-rv5j1201	657	12	(	(	-LRB-
cord-022561-rv5j1201	657	13	hypofunction	hypofunction	NN
cord-022561-rv5j1201	657	14	or	or	CC
cord-022561-rv5j1201	657	15	hyperfunction	hyperfunction	NN
cord-022561-rv5j1201	657	16	)	)	-RRB-
cord-022561-rv5j1201	657	17	by	by	IN
cord-022561-rv5j1201	657	18	altering	alter	VBG
cord-022561-rv5j1201	657	19	platelet	platelet	NN
cord-022561-rv5j1201	657	20	adhesion	adhesion	NN
cord-022561-rv5j1201	657	21	or	or	CC
cord-022561-rv5j1201	657	22	aggregation	aggregation	NN
cord-022561-rv5j1201	657	23	or	or	CC
cord-022561-rv5j1201	657	24	by	by	IN
cord-022561-rv5j1201	657	25	mechanisms	mechanism	NNS
cord-022561-rv5j1201	657	26	that	that	WDT
cord-022561-rv5j1201	657	27	are	be	VBP
cord-022561-rv5j1201	657	28	not	not	RB
cord-022561-rv5j1201	657	29	fully	fully	RB
cord-022561-rv5j1201	657	30	understood	understand	VBN
cord-022561-rv5j1201	657	31	.	.	.
cord-022561-rv5j1201	658	1	Box	Box	NNP
cord-022561-rv5j1201	658	2	13	13	CD
cord-022561-rv5j1201	658	3	-	-	SYM
cord-022561-rv5j1201	658	4	2	2	CD
cord-022561-rv5j1201	658	5	shows	show	VBZ
cord-022561-rv5j1201	658	6	underlying	underlie	VBG
cord-022561-rv5j1201	658	7	conditions	condition	NNS
cord-022561-rv5j1201	658	8	having	have	VBG
cord-022561-rv5j1201	658	9	secondary	secondary	JJ
cord-022561-rv5j1201	658	10	platelet	platelet	NN
cord-022561-rv5j1201	658	11	dysfunction	dysfunction	NN
cord-022561-rv5j1201	658	12	.	.	.
cord-022561-rv5j1201	659	1	clear	clear	JJ
cord-022561-rv5j1201	659	2	.	.	.
cord-022561-rv5j1201	660	1	There	there	EX
cord-022561-rv5j1201	660	2	is	be	VBZ
cord-022561-rv5j1201	660	3	also	also	RB
cord-022561-rv5j1201	660	4	a	a	DT
cord-022561-rv5j1201	660	5	rare	rare	JJ
cord-022561-rv5j1201	660	6	form	form	NN
cord-022561-rv5j1201	660	7	of	of	IN
cord-022561-rv5j1201	660	8	megakaryocytic	megakaryocytic	JJ
cord-022561-rv5j1201	660	9	leukemia	leukemia	NN
cord-022561-rv5j1201	660	10	known	know	VBN
cord-022561-rv5j1201	660	11	as	as	IN
cord-022561-rv5j1201	660	12	essential	essential	JJ
cord-022561-rv5j1201	660	13	thrombocythemia	thrombocythemia	NN
cord-022561-rv5j1201	660	14	,	,	,
cord-022561-rv5j1201	660	15	which	which	WDT
cord-022561-rv5j1201	660	16	is	be	VBZ
cord-022561-rv5j1201	660	17	characterized	characterize	VBN
cord-022561-rv5j1201	660	18	by	by	IN
cord-022561-rv5j1201	660	19	marked	mark	VBN
cord-022561-rv5j1201	660	20	thrombocytosis	thrombocytosis	NN
cord-022561-rv5j1201	660	21	.	.	.
cord-022561-rv5j1201	661	1	Lymphocytosis	Lymphocytosis	NNP
cord-022561-rv5j1201	661	2	.	.	.
cord-022561-rv5j1201	662	1	Lymphocytosis	Lymphocytosis	NNP
cord-022561-rv5j1201	662	2	refers	refer	VBZ
cord-022561-rv5j1201	662	3	to	to	IN
cord-022561-rv5j1201	662	4	an	an	DT
cord-022561-rv5j1201	662	5	increase	increase	NN
cord-022561-rv5j1201	662	6	in	in	IN
cord-022561-rv5j1201	662	7	the	the	DT
cord-022561-rv5j1201	662	8	concentration	concentration	NN
cord-022561-rv5j1201	662	9	of	of	IN
cord-022561-rv5j1201	662	10	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	662	11	in	in	IN
cord-022561-rv5j1201	662	12	blood	blood	NN
cord-022561-rv5j1201	662	13	circulation	circulation	NN
cord-022561-rv5j1201	662	14	.	.	.
cord-022561-rv5j1201	663	1	There	there	EX
cord-022561-rv5j1201	663	2	are	be	VBP
cord-022561-rv5j1201	663	3	several	several	JJ
cord-022561-rv5j1201	663	4	causes	cause	NNS
cord-022561-rv5j1201	663	5	of	of	IN
cord-022561-rv5j1201	663	6	lymphocytosis	lymphocytosis	NN
cord-022561-rv5j1201	663	7	,	,	,
cord-022561-rv5j1201	663	8	including	include	VBG
cord-022561-rv5j1201	663	9	age	age	NN
cord-022561-rv5j1201	663	10	,	,	,
cord-022561-rv5j1201	663	11	excessive	excessive	JJ
cord-022561-rv5j1201	663	12	epinephrine	epinephrine	NN
cord-022561-rv5j1201	663	13	,	,	,
cord-022561-rv5j1201	663	14	chronic	chronic	JJ
cord-022561-rv5j1201	663	15	inflammation	inflammation	NN
cord-022561-rv5j1201	663	16	,	,	,
cord-022561-rv5j1201	663	17	hypoadrenocorticism	hypoadrenocorticism	NN
cord-022561-rv5j1201	663	18	,	,	,
cord-022561-rv5j1201	663	19	and	and	CC
cord-022561-rv5j1201	663	20	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	663	21	neoplasia	neoplasia	NN
cord-022561-rv5j1201	663	22	;	;	:
cord-022561-rv5j1201	663	23	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	663	24	neoplasms	neoplasm	NNS
cord-022561-rv5j1201	663	25	are	be	VBP
cord-022561-rv5j1201	663	26	presented	present	VBN
cord-022561-rv5j1201	663	27	later	later	RB
cord-022561-rv5j1201	663	28	in	in	IN
cord-022561-rv5j1201	663	29	the	the	DT
cord-022561-rv5j1201	663	30	chapter	chapter	NN
cord-022561-rv5j1201	663	31	.	.	.
cord-022561-rv5j1201	664	1	Young	young	JJ
cord-022561-rv5j1201	664	2	animals	animal	NNS
cord-022561-rv5j1201	664	3	normally	normally	RB
cord-022561-rv5j1201	664	4	have	have	VBP
cord-022561-rv5j1201	664	5	higher	high	JJR
cord-022561-rv5j1201	664	6	concentrations	concentration	NNS
cord-022561-rv5j1201	664	7	of	of	IN
cord-022561-rv5j1201	664	8	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	664	9	than	than	IN
cord-022561-rv5j1201	664	10	older	old	JJR
cord-022561-rv5j1201	664	11	animals	animal	NNS
cord-022561-rv5j1201	664	12	,	,	,
cord-022561-rv5j1201	664	13	and	and	CC
cord-022561-rv5j1201	664	14	normal	normal	JJ
cord-022561-rv5j1201	664	15	healthy	healthy	JJ
cord-022561-rv5j1201	664	16	young	young	JJ
cord-022561-rv5j1201	664	17	animals	animal	NNS
cord-022561-rv5j1201	664	18	may	may	MD
cord-022561-rv5j1201	664	19	have	have	VB
cord-022561-rv5j1201	664	20	counts	count	NNS
cord-022561-rv5j1201	664	21	that	that	IN
cord-022561-rv5j1201	664	22	exceed	exceed	VBP
cord-022561-rv5j1201	664	23	adult	adult	NN
cord-022561-rv5j1201	664	24	reference	reference	NN
cord-022561-rv5j1201	664	25	values	value	NNS
cord-022561-rv5j1201	664	26	.	.	.
cord-022561-rv5j1201	665	1	Because	because	IN
cord-022561-rv5j1201	665	2	this	this	DT
cord-022561-rv5j1201	665	3	is	be	VBZ
cord-022561-rv5j1201	665	4	not	not	RB
cord-022561-rv5j1201	665	5	pathologic	pathologic	JJ
cord-022561-rv5j1201	665	6	lymphocytosis	lymphocytosis	NN
cord-022561-rv5j1201	665	7	,	,	,
cord-022561-rv5j1201	665	8	but	but	CC
cord-022561-rv5j1201	665	9	normal	normal	JJ
cord-022561-rv5j1201	665	10	physiologic	physiologic	JJ
cord-022561-rv5j1201	665	11	variation	variation	NN
cord-022561-rv5j1201	665	12	,	,	,
cord-022561-rv5j1201	665	13	it	-PRON-	PRP
cord-022561-rv5j1201	665	14	is	be	VBZ
cord-022561-rv5j1201	665	15	often	often	RB
cord-022561-rv5j1201	665	16	termed	term	VBN
cord-022561-rv5j1201	665	17	pseudolymphocytosis	pseudolymphocytosis	NN
cord-022561-rv5j1201	665	18	of	of	IN
cord-022561-rv5j1201	665	19	young	young	JJ
cord-022561-rv5j1201	665	20	animals	animal	NNS
cord-022561-rv5j1201	665	21	.	.	.
cord-022561-rv5j1201	666	1	As	as	IN
cord-022561-rv5j1201	666	2	discussed	discuss	VBN
cord-022561-rv5j1201	666	3	earlier	early	RBR
cord-022561-rv5j1201	666	4	in	in	IN
cord-022561-rv5j1201	666	5	the	the	DT
cord-022561-rv5j1201	666	6	section	section	NN
cord-022561-rv5j1201	666	7	on	on	IN
cord-022561-rv5j1201	666	8	neutrophilia	neutrophilia	NNP
cord-022561-rv5j1201	666	9	,	,	,
cord-022561-rv5j1201	666	10	lymphocytosis	lymphocytosis	NNP
cord-022561-rv5j1201	666	11	is	be	VBZ
cord-022561-rv5j1201	666	12	also	also	RB
cord-022561-rv5j1201	666	13	a	a	DT
cord-022561-rv5j1201	666	14	feature	feature	NN
cord-022561-rv5j1201	666	15	of	of	IN
cord-022561-rv5j1201	666	16	epinephrine	epinephrine	NN
cord-022561-rv5j1201	666	17	-	-	HYPH
cord-022561-rv5j1201	666	18	mediated	mediate	VBN
cord-022561-rv5j1201	666	19	physiologic	physiologic	JJ
cord-022561-rv5j1201	666	20	leukocytosis	leukocytosis	NN
cord-022561-rv5j1201	666	21	,	,	,
cord-022561-rv5j1201	666	22	resulting	result	VBG
cord-022561-rv5j1201	666	23	from	from	IN
cord-022561-rv5j1201	666	24	redistribution	redistribution	NN
cord-022561-rv5j1201	666	25	of	of	IN
cord-022561-rv5j1201	666	26	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	666	27	from	from	IN
cord-022561-rv5j1201	666	28	the	the	DT
cord-022561-rv5j1201	666	29	blood	blood	NN
cord-022561-rv5j1201	666	30	marginating	marginate	VBG
cord-022561-rv5j1201	666	31	pool	pool	NN
cord-022561-rv5j1201	666	32	into	into	IN
cord-022561-rv5j1201	666	33	the	the	DT
cord-022561-rv5j1201	666	34	blood	blood	NN
cord-022561-rv5j1201	666	35	circulating	circulate	VBG
cord-022561-rv5j1201	666	36	pool	pool	NN
cord-022561-rv5j1201	666	37	.	.	.
cord-022561-rv5j1201	667	1	Epinephrine	epinephrine	NN
cord-022561-rv5j1201	667	2	-	-	HYPH
cord-022561-rv5j1201	667	3	mediated	mediate	VBN
cord-022561-rv5j1201	667	4	lymphocytosis	lymphocytosis	NN
cord-022561-rv5j1201	667	5	may	may	MD
cord-022561-rv5j1201	667	6	be	be	VB
cord-022561-rv5j1201	667	7	more	more	RBR
cord-022561-rv5j1201	667	8	marked	marked	JJ
cord-022561-rv5j1201	667	9	than	than	IN
cord-022561-rv5j1201	667	10	neutrophilia	neutrophilia	NNP
cord-022561-rv5j1201	667	11	,	,	,
cord-022561-rv5j1201	667	12	particularly	particularly	RB
cord-022561-rv5j1201	667	13	in	in	IN
cord-022561-rv5j1201	667	14	cats	cat	NNS
cord-022561-rv5j1201	667	15	(	(	-LRB-
cord-022561-rv5j1201	667	16	lymphocyte	lymphocyte	NN
cord-022561-rv5j1201	667	17	counts	count	NNS
cord-022561-rv5j1201	667	18	of	of	IN
cord-022561-rv5j1201	667	19	>	>	$
cord-022561-rv5j1201	667	20	20,000/µL	20,000/µl	CD
cord-022561-rv5j1201	667	21	are	be	VBP
cord-022561-rv5j1201	667	22	not	not	RB
cord-022561-rv5j1201	667	23	uncommon	uncommon	JJ
cord-022561-rv5j1201	667	24	)	)	-RRB-
cord-022561-rv5j1201	667	25	.	.	.
cord-022561-rv5j1201	668	1	Antigenic	antigenic	JJ
cord-022561-rv5j1201	668	2	stimulation	stimulation	NN
cord-022561-rv5j1201	668	3	may	may	MD
cord-022561-rv5j1201	668	4	result	result	VB
cord-022561-rv5j1201	668	5	in	in	IN
cord-022561-rv5j1201	668	6	lymphocytosis	lymphocytosis	NN
cord-022561-rv5j1201	668	7	,	,	,
cord-022561-rv5j1201	668	8	which	which	WDT
cord-022561-rv5j1201	668	9	may	may	MD
cord-022561-rv5j1201	668	10	be	be	VB
cord-022561-rv5j1201	668	11	marked	mark	VBN
cord-022561-rv5j1201	668	12	in	in	IN
cord-022561-rv5j1201	668	13	rare	rare	JJ
cord-022561-rv5j1201	668	14	cases	case	NNS
cord-022561-rv5j1201	668	15	(	(	-LRB-
cord-022561-rv5j1201	668	16	up	up	IN
cord-022561-rv5j1201	668	17	to	to	IN
cord-022561-rv5j1201	668	18	approximately	approximately	RB
cord-022561-rv5j1201	668	19	30,000/µL	30,000/µl	CD
cord-022561-rv5j1201	668	20	in	in	IN
cord-022561-rv5j1201	668	21	dogs	dog	NNS
cord-022561-rv5j1201	668	22	and	and	CC
cord-022561-rv5j1201	668	23	40,000/µL	40,000/µl	CD
cord-022561-rv5j1201	668	24	in	in	IN
cord-022561-rv5j1201	668	25	cats	cat	NNS
cord-022561-rv5j1201	668	26	)	)	-RRB-
cord-022561-rv5j1201	668	27	;	;	:
cord-022561-rv5j1201	668	28	however	however	RB
cord-022561-rv5j1201	668	29	,	,	,
cord-022561-rv5j1201	668	30	this	this	DT
cord-022561-rv5j1201	668	31	is	be	VBZ
cord-022561-rv5j1201	668	32	not	not	RB
cord-022561-rv5j1201	668	33	usually	usually	RB
cord-022561-rv5j1201	668	34	the	the	DT
cord-022561-rv5j1201	668	35	case	case	NN
cord-022561-rv5j1201	668	36	,	,	,
cord-022561-rv5j1201	668	37	even	even	RB
cord-022561-rv5j1201	668	38	when	when	WRB
cord-022561-rv5j1201	668	39	there	there	EX
cord-022561-rv5j1201	668	40	is	be	VBZ
cord-022561-rv5j1201	668	41	clear	clear	JJ
cord-022561-rv5j1201	668	42	evidence	evidence	NN
cord-022561-rv5j1201	668	43	of	of	IN
cord-022561-rv5j1201	668	44	increased	increase	VBN
cord-022561-rv5j1201	668	45	immunologic	immunologic	JJ
cord-022561-rv5j1201	668	46	activity	activity	NN
cord-022561-rv5j1201	668	47	in	in	IN
cord-022561-rv5j1201	668	48	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	668	49	tissues	tissue	NNS
cord-022561-rv5j1201	668	50	.	.	.
cord-022561-rv5j1201	669	1	In	in	IN
cord-022561-rv5j1201	669	2	cases	case	NNS
cord-022561-rv5j1201	669	3	of	of	IN
cord-022561-rv5j1201	669	4	antigenic	antigenic	JJ
cord-022561-rv5j1201	669	5	stimulation	stimulation	NN
cord-022561-rv5j1201	669	6	,	,	,
cord-022561-rv5j1201	669	7	it	-PRON-	PRP
cord-022561-rv5j1201	669	8	is	be	VBZ
cord-022561-rv5j1201	669	9	common	common	JJ
cord-022561-rv5j1201	669	10	for	for	IN
cord-022561-rv5j1201	669	11	a	a	DT
cord-022561-rv5j1201	669	12	minority	minority	NN
cord-022561-rv5j1201	669	13	of	of	IN
cord-022561-rv5j1201	669	14	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	669	15	to	to	TO
cord-022561-rv5j1201	669	16	have	have	VB
cord-022561-rv5j1201	669	17	"	"	``
cord-022561-rv5j1201	669	18	reactive	reactive	JJ
cord-022561-rv5j1201	669	19	"	"	''
cord-022561-rv5j1201	669	20	morphologic	morphologic	JJ
cord-022561-rv5j1201	669	21	features	feature	NNS
cord-022561-rv5j1201	669	22	-	-	HYPH
cord-022561-rv5j1201	669	23	larger	large	JJR
cord-022561-rv5j1201	669	24	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	669	25	with	with	IN
cord-022561-rv5j1201	669	26	more	more	RBR
cord-022561-rv5j1201	669	27	abundant	abundant	JJ
cord-022561-rv5j1201	669	28	,	,	,
cord-022561-rv5j1201	669	29	deeply	deeply	RB
cord-022561-rv5j1201	669	30	basophilic	basophilic	JJ
cord-022561-rv5j1201	669	31	cytoplasm	cytoplasm	NN
cord-022561-rv5j1201	669	32	and	and	CC
cord-022561-rv5j1201	669	33	more	more	RBR
cord-022561-rv5j1201	669	34	open	open	JJ
cord-022561-rv5j1201	669	35	chromatin	chromatin	NN
cord-022561-rv5j1201	670	1	(	(	-LRB-
cord-022561-rv5j1201	670	2	Fig	Fig	NNP
cord-022561-rv5j1201	670	3	.	.	.
cord-022561-rv5j1201	670	4	13	13	CD
cord-022561-rv5j1201	670	5	-	-	SYM
cord-022561-rv5j1201	670	6	19	19	CD
cord-022561-rv5j1201	670	7	)	)	-RRB-
cord-022561-rv5j1201	670	8	.	.	.
cord-022561-rv5j1201	671	1	Just	just	RB
cord-022561-rv5j1201	671	2	as	as	IN
cord-022561-rv5j1201	671	3	glucocorticoid	glucocorticoid	NN
cord-022561-rv5j1201	671	4	excess	excess	NN
cord-022561-rv5j1201	671	5	can	can	MD
cord-022561-rv5j1201	671	6	cause	cause	VB
cord-022561-rv5j1201	671	7	lymphopenia	lymphopenia	NNP
cord-022561-rv5j1201	671	8	,	,	,
cord-022561-rv5j1201	671	9	glucocorticoid	glucocorticoid	NN
cord-022561-rv5j1201	671	10	deficiency	deficiency	NN
cord-022561-rv5j1201	671	11	(	(	-LRB-
cord-022561-rv5j1201	671	12	hypoadrenocorticism	hypoadrenocorticism	NNP
cord-022561-rv5j1201	671	13	)	)	-RRB-
cord-022561-rv5j1201	671	14	can	can	MD
cord-022561-rv5j1201	671	15	cause	cause	VB
cord-022561-rv5j1201	671	16	lymphocytosis	lymphocytosis	NN
cord-022561-rv5j1201	671	17	,	,	,
cord-022561-rv5j1201	671	18	or	or	CC
cord-022561-rv5j1201	671	19	lack	lack	NN
cord-022561-rv5j1201	671	20	of	of	IN
cord-022561-rv5j1201	671	21	lymphopenia	lymphopenia	NNP
cord-022561-rv5j1201	671	22	during	during	IN
cord-022561-rv5j1201	671	23	conditions	condition	NNS
cord-022561-rv5j1201	671	24	of	of	IN
cord-022561-rv5j1201	671	25	stress	stress	NN
cord-022561-rv5j1201	671	26	that	that	WDT
cord-022561-rv5j1201	671	27	typically	typically	RB
cord-022561-rv5j1201	671	28	result	result	VBP
cord-022561-rv5j1201	671	29	in	in	IN
cord-022561-rv5j1201	671	30	glucocorticoid	glucocorticoid	NN
cord-022561-rv5j1201	671	31	-	-	HYPH
cord-022561-rv5j1201	671	32	mediated	mediate	VBN
cord-022561-rv5j1201	671	33	lymphopenia	lymphopenia	NNP
cord-022561-rv5j1201	671	34	.	.	.
cord-022561-rv5j1201	672	1	A	a	DT
cord-022561-rv5j1201	672	2	condition	condition	NN
cord-022561-rv5j1201	672	3	known	know	VBN
cord-022561-rv5j1201	672	4	as	as	IN
cord-022561-rv5j1201	672	5	persistent	persistent	JJ
cord-022561-rv5j1201	672	6	lymphocytosis	lymphocytosis	NN
cord-022561-rv5j1201	672	7	(	(	-LRB-
cord-022561-rv5j1201	672	8	PL	PL	NNP
cord-022561-rv5j1201	672	9	)	)	-RRB-
cord-022561-rv5j1201	672	10	occurs	occur	VBZ
cord-022561-rv5j1201	672	11	in	in	IN
cord-022561-rv5j1201	672	12	approximately	approximately	RB
cord-022561-rv5j1201	672	13	30	30	CD
cord-022561-rv5j1201	672	14	%	%	NN
cord-022561-rv5j1201	672	15	of	of	IN
cord-022561-rv5j1201	672	16	cattle	cattle	NNS
cord-022561-rv5j1201	672	17	infected	infect	VBN
cord-022561-rv5j1201	672	18	with	with	IN
cord-022561-rv5j1201	672	19	the	the	DT
cord-022561-rv5j1201	672	20	bovine	bovine	JJ
cord-022561-rv5j1201	672	21	leukemia	leukemia	NN
cord-022561-rv5j1201	672	22	virus	virus	NN
cord-022561-rv5j1201	672	23	(	(	-LRB-
cord-022561-rv5j1201	672	24	BLV	BLV	NNP
cord-022561-rv5j1201	672	25	)	)	-RRB-
cord-022561-rv5j1201	672	26	.	.	.
cord-022561-rv5j1201	673	1	The	the	DT
cord-022561-rv5j1201	673	2	condition	condition	NN
cord-022561-rv5j1201	673	3	is	be	VBZ
cord-022561-rv5j1201	673	4	defined	define	VBN
cord-022561-rv5j1201	673	5	as	as	IN
cord-022561-rv5j1201	673	6	an	an	DT
cord-022561-rv5j1201	673	7	increase	increase	NN
cord-022561-rv5j1201	673	8	in	in	IN
cord-022561-rv5j1201	673	9	the	the	DT
cord-022561-rv5j1201	673	10	blood	blood	NN
cord-022561-rv5j1201	673	11	concentration	concentration	NN
cord-022561-rv5j1201	673	12	of	of	IN
cord-022561-rv5j1201	673	13	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	673	14	above	above	IN
cord-022561-rv5j1201	673	15	the	the	DT
cord-022561-rv5j1201	673	16	reference	reference	NN
cord-022561-rv5j1201	673	17	interval	interval	NN
cord-022561-rv5j1201	673	18	for	for	IN
cord-022561-rv5j1201	673	19	at	at	RB
cord-022561-rv5j1201	673	20	least	least	JJS
cord-022561-rv5j1201	673	21	3	3	CD
cord-022561-rv5j1201	673	22	months	month	NNS
cord-022561-rv5j1201	673	23	.	.	.
cord-022561-rv5j1201	674	1	This	this	DT
cord-022561-rv5j1201	674	2	form	form	NN
cord-022561-rv5j1201	674	3	of	of	IN
cord-022561-rv5j1201	674	4	lymphocytosis	lymphocytosis	NN
cord-022561-rv5j1201	674	5	is	be	VBZ
cord-022561-rv5j1201	674	6	a	a	DT
cord-022561-rv5j1201	674	7	nonneoplastic	nonneoplastic	JJ
cord-022561-rv5j1201	674	8	proliferation	proliferation	NN
cord-022561-rv5j1201	674	9	(	(	-LRB-
cord-022561-rv5j1201	674	10	i.e.	i.e.	FW
cord-022561-rv5j1201	674	11	,	,	,
cord-022561-rv5j1201	674	12	hyperplasia	hyperplasia	NN
cord-022561-rv5j1201	674	13	)	)	-RRB-
cord-022561-rv5j1201	674	14	of	of	IN
cord-022561-rv5j1201	674	15	B	b	NN
cord-022561-rv5j1201	674	16	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	674	17	.	.	.
cord-022561-rv5j1201	675	1	In	in	IN
cord-022561-rv5j1201	675	2	the	the	DT
cord-022561-rv5j1201	675	3	absence	absence	NN
cord-022561-rv5j1201	675	4	of	of	IN
cord-022561-rv5j1201	675	5	other	other	JJ
cord-022561-rv5j1201	675	6	disease	disease	NN
cord-022561-rv5j1201	675	7	,	,	,
cord-022561-rv5j1201	675	8	cattle	cattle	NNS
cord-022561-rv5j1201	675	9	with	with	IN
cord-022561-rv5j1201	675	10	persistent	persistent	JJ
cord-022561-rv5j1201	675	11	lymphocytosis	lymphocytosis	NN
cord-022561-rv5j1201	675	12	are	be	VBP
cord-022561-rv5j1201	675	13	asymptomatic	asymptomatic	JJ
cord-022561-rv5j1201	675	14	.	.	.
cord-022561-rv5j1201	676	1	However	however	RB
cord-022561-rv5j1201	676	2	,	,	,
cord-022561-rv5j1201	676	3	cattle	cattle	NNS
cord-022561-rv5j1201	676	4	infected	infect	VBN
cord-022561-rv5j1201	676	5	with	with	IN
cord-022561-rv5j1201	676	6	BLV	BLV	NNP
cord-022561-rv5j1201	676	7	,	,	,
cord-022561-rv5j1201	676	8	especially	especially	RB
cord-022561-rv5j1201	676	9	those	those	DT
cord-022561-rv5j1201	676	10	animals	animal	NNS
cord-022561-rv5j1201	676	11	with	with	IN
cord-022561-rv5j1201	676	12	persistent	persistent	JJ
cord-022561-rv5j1201	676	13	lymphocytosis	lymphocytosis	NN
cord-022561-rv5j1201	676	14	,	,	,
cord-022561-rv5j1201	676	15	are	be	VBP
cord-022561-rv5j1201	676	16	at	at	IN
cord-022561-rv5j1201	676	17	increased	increase	VBN
cord-022561-rv5j1201	676	18	risk	risk	NN
cord-022561-rv5j1201	676	19	for	for	IN
cord-022561-rv5j1201	676	20	developing	develop	VBG
cord-022561-rv5j1201	676	21	B	b	NN
cord-022561-rv5j1201	676	22	lymphocyte	lymphocyte	NN
cord-022561-rv5j1201	676	23	lymphoma	lymphoma	NN
cord-022561-rv5j1201	676	24	.	.	.
cord-022561-rv5j1201	676	25	 	 	_SP
cord-022561-rv5j1201	677	1	Aplastic	Aplastic	NNP
cord-022561-rv5j1201	677	2	Anemia	anemia	NN
cord-022561-rv5j1201	677	3	(	(	-LRB-
cord-022561-rv5j1201	677	4	Aplastic	Aplastic	NNP
cord-022561-rv5j1201	677	5	Pancytopenia	Pancytopenia	NNP
cord-022561-rv5j1201	677	6	)	)	-RRB-
cord-022561-rv5j1201	678	1	Aplastic	aplastic	JJ
cord-022561-rv5j1201	678	2	anemia	anemia	NN
cord-022561-rv5j1201	678	3	,	,	,
cord-022561-rv5j1201	678	4	or	or	CC
cord-022561-rv5j1201	678	5	more	more	RBR
cord-022561-rv5j1201	678	6	accurately	accurately	RB
cord-022561-rv5j1201	678	7	aplastic	aplastic	JJ
cord-022561-rv5j1201	678	8	pancytopenia	pancytopenia	NNP
cord-022561-rv5j1201	678	9	,	,	,
cord-022561-rv5j1201	678	10	is	be	VBZ
cord-022561-rv5j1201	678	11	a	a	DT
cord-022561-rv5j1201	678	12	rare	rare	JJ
cord-022561-rv5j1201	678	13	condition	condition	NN
cord-022561-rv5j1201	678	14	characterized	characterize	VBN
cord-022561-rv5j1201	678	15	by	by	IN
cord-022561-rv5j1201	678	16	aplasia	aplasia	NNP
cord-022561-rv5j1201	678	17	or	or	CC
cord-022561-rv5j1201	678	18	severe	severe	JJ
cord-022561-rv5j1201	678	19	hypoplasia	hypoplasia	NN
cord-022561-rv5j1201	678	20	of	of	IN
cord-022561-rv5j1201	678	21	all	all	DT
cord-022561-rv5j1201	678	22	hematopoietic	hematopoietic	JJ
cord-022561-rv5j1201	678	23	lineages	lineage	NNS
cord-022561-rv5j1201	678	24	in	in	IN
cord-022561-rv5j1201	678	25	the	the	DT
cord-022561-rv5j1201	678	26	bone	bone	NN
cord-022561-rv5j1201	678	27	marrow	marrow	NN
cord-022561-rv5j1201	678	28	with	with	IN
cord-022561-rv5j1201	678	29	resulting	result	VBG
cord-022561-rv5j1201	678	30	cytopenias	cytopenia	NNS
cord-022561-rv5j1201	678	31	.	.	.
cord-022561-rv5j1201	679	1	The	the	DT
cord-022561-rv5j1201	679	2	term	term	NN
cord-022561-rv5j1201	679	3	aplastic	aplastic	JJ
cord-022561-rv5j1201	679	4	anemia	anemia	NN
cord-022561-rv5j1201	679	5	is	be	VBZ
cord-022561-rv5j1201	679	6	a	a	DT
cord-022561-rv5j1201	679	7	misnomer	misnomer	NN
cord-022561-rv5j1201	679	8	because	because	IN
cord-022561-rv5j1201	679	9	affected	affected	JJ
cord-022561-rv5j1201	679	10	cells	cell	NNS
cord-022561-rv5j1201	679	11	are	be	VBP
cord-022561-rv5j1201	679	12	not	not	RB
cord-022561-rv5j1201	679	13	limited	limited	JJ
cord-022561-rv5j1201	679	14	to	to	IN
cord-022561-rv5j1201	679	15	the	the	DT
cord-022561-rv5j1201	679	16	erythroid	erythroid	NN
cord-022561-rv5j1201	679	17	lineage	lineage	NN
cord-022561-rv5j1201	679	18	.	.	.
cord-022561-rv5j1201	680	1	Many	many	JJ
cord-022561-rv5j1201	680	2	of	of	IN
cord-022561-rv5j1201	680	3	the	the	DT
cord-022561-rv5j1201	680	4	conditions	condition	NNS
cord-022561-rv5j1201	680	5	reported	report	VBN
cord-022561-rv5j1201	680	6	to	to	TO
cord-022561-rv5j1201	680	7	cause	cause	VB
cord-022561-rv5j1201	680	8	aplastic	aplastic	JJ
cord-022561-rv5j1201	680	9	anemia	anemia	NN
cord-022561-rv5j1201	680	10	do	do	VBP
cord-022561-rv5j1201	680	11	so	so	RB
cord-022561-rv5j1201	680	12	only	only	RB
cord-022561-rv5j1201	680	13	rarely	rarely	RB
cord-022561-rv5j1201	680	14	or	or	CC
cord-022561-rv5j1201	680	15	idiosyncratically	idiosyncratically	RB
cord-022561-rv5j1201	680	16	;	;	:
cord-022561-rv5j1201	680	17	more	more	RBR
cord-022561-rv5j1201	680	18	frequently	frequently	RB
cord-022561-rv5j1201	680	19	,	,	,
cord-022561-rv5j1201	680	20	they	-PRON-	PRP
cord-022561-rv5j1201	680	21	cause	cause	VBP
cord-022561-rv5j1201	680	22	other	other	JJ
cord-022561-rv5j1201	680	23	hematologic	hematologic	JJ
cord-022561-rv5j1201	680	24	or	or	CC
cord-022561-rv5j1201	680	25	nonhematologic	nonhematologic	JJ
cord-022561-rv5j1201	680	26	abnormalities	abnormality	NNS
cord-022561-rv5j1201	680	27	.	.	.
cord-022561-rv5j1201	681	1	A	a	DT
cord-022561-rv5j1201	681	2	partial	partial	JJ
cord-022561-rv5j1201	681	3	list	list	NN
cord-022561-rv5j1201	681	4	of	of	IN
cord-022561-rv5j1201	681	5	reported	report	VBN
cord-022561-rv5j1201	681	6	causes	cause	NNS
cord-022561-rv5j1201	681	7	of	of	IN
cord-022561-rv5j1201	681	8	aplastic	aplastic	JJ
cord-022561-rv5j1201	681	9	anemia	anemia	NN
cord-022561-rv5j1201	681	10	in	in	IN
cord-022561-rv5j1201	681	11	domestic	domestic	JJ
cord-022561-rv5j1201	681	12	animals	animal	NNS
cord-022561-rv5j1201	681	13	includes	include	VBZ
cord-022561-rv5j1201	681	14	the	the	DT
cord-022561-rv5j1201	681	15	following	follow	VBG
cord-022561-rv5j1201	681	16	:	:	:
cord-022561-rv5j1201	681	17	Most	Most	JJS
cord-022561-rv5j1201	681	18	of	of	IN
cord-022561-rv5j1201	681	19	these	these	DT
cord-022561-rv5j1201	681	20	causes	cause	NNS
cord-022561-rv5j1201	681	21	,	,	,
cord-022561-rv5j1201	681	22	especially	especially	RB
cord-022561-rv5j1201	681	23	the	the	DT
cord-022561-rv5j1201	681	24	chemical	chemical	JJ
cord-022561-rv5j1201	681	25	agents	agent	NNS
cord-022561-rv5j1201	681	26	,	,	,
cord-022561-rv5j1201	681	27	are	be	VBP
cord-022561-rv5j1201	681	28	directly	directly	RB
cord-022561-rv5j1201	681	29	cytotoxic	cytotoxic	JJ
cord-022561-rv5j1201	681	30	to	to	IN
cord-022561-rv5j1201	681	31	HSCs	hscs	NN
cord-022561-rv5j1201	681	32	or	or	CC
cord-022561-rv5j1201	681	33	progenitor	progenitor	NN
cord-022561-rv5j1201	681	34	cells	cell	NNS
cord-022561-rv5j1201	681	35	,	,	,
cord-022561-rv5j1201	681	36	resulting	result	VBG
cord-022561-rv5j1201	681	37	in	in	IN
cord-022561-rv5j1201	681	38	their	-PRON-	PRP$
cord-022561-rv5j1201	681	39	destruction	destruction	NN
cord-022561-rv5j1201	681	40	.	.	.
cord-022561-rv5j1201	682	1	However	however	RB
cord-022561-rv5j1201	682	2	,	,	,
cord-022561-rv5j1201	682	3	another	another	DT
cord-022561-rv5j1201	682	4	proposed	propose	VBN
cord-022561-rv5j1201	682	5	mechanism	mechanism	NN
cord-022561-rv5j1201	682	6	is	be	VBZ
cord-022561-rv5j1201	682	7	disruption	disruption	NN
cord-022561-rv5j1201	682	8	of	of	IN
cord-022561-rv5j1201	682	9	normal	normal	JJ
cord-022561-rv5j1201	682	10	stem	stem	NN
cord-022561-rv5j1201	682	11	cell	cell	NN
cord-022561-rv5j1201	682	12	function	function	NN
cord-022561-rv5j1201	682	13	because	because	IN
cord-022561-rv5j1201	682	14	of	of	IN
cord-022561-rv5j1201	682	15	mutation	mutation	NN
cord-022561-rv5j1201	682	16	or	or	CC
cord-022561-rv5j1201	682	17	perturbation	perturbation	NN
cord-022561-rv5j1201	682	18	of	of	IN
cord-022561-rv5j1201	682	19	hematopoietic	hematopoietic	JJ
cord-022561-rv5j1201	682	20	cells	cell	NNS
cord-022561-rv5j1201	682	21	and/or	and/or	CC
cord-022561-rv5j1201	682	22	their	-PRON-	PRP$
cord-022561-rv5j1201	682	23	microenvironment	microenvironment	NN
cord-022561-rv5j1201	682	24	.	.	.
cord-022561-rv5j1201	683	1	This	this	DT
cord-022561-rv5j1201	683	2	pathogenesis	pathogenesis	NN
cord-022561-rv5j1201	683	3	is	be	VBZ
cord-022561-rv5j1201	683	4	mostly	mostly	RB
cord-022561-rv5j1201	683	5	recognized	recognize	VBN
cord-022561-rv5j1201	683	6	in	in	IN
cord-022561-rv5j1201	683	7	retroviral	retroviral	JJ
cord-022561-rv5j1201	683	8	infections	infection	NNS
cord-022561-rv5j1201	683	9	.	.	.
cord-022561-rv5j1201	684	1	Aplastic	aplastic	JJ
cord-022561-rv5j1201	684	2	anemia	anemia	NN
cord-022561-rv5j1201	684	3	occurs	occur	VBZ
cord-022561-rv5j1201	684	4	in	in	IN
cord-022561-rv5j1201	684	5	both	both	CC
cord-022561-rv5j1201	684	6	acute	acute	JJ
cord-022561-rv5j1201	684	7	and	and	CC
cord-022561-rv5j1201	684	8	chronic	chronic	JJ
cord-022561-rv5j1201	684	9	forms	form	NNS
cord-022561-rv5j1201	684	10	.	.	.
cord-022561-rv5j1201	685	1	Most	Most	JJS
cord-022561-rv5j1201	685	2	of	of	IN
cord-022561-rv5j1201	685	3	the	the	DT
cord-022561-rv5j1201	685	4	chemical	chemical	NN
cord-022561-rv5j1201	685	5	causes	cause	NNS
cord-022561-rv5j1201	685	6	result	result	VBP
cord-022561-rv5j1201	685	7	in	in	IN
cord-022561-rv5j1201	685	8	acute	acute	JJ
cord-022561-rv5j1201	685	9	disease	disease	NN
cord-022561-rv5j1201	685	10	.	.	.
cord-022561-rv5j1201	686	1	Grossly	grossly	RB
cord-022561-rv5j1201	686	2	,	,	,
cord-022561-rv5j1201	686	3	affected	affected	JJ
cord-022561-rv5j1201	686	4	animals	animal	NNS
cord-022561-rv5j1201	686	5	may	may	MD
cord-022561-rv5j1201	686	6	show	show	VB
cord-022561-rv5j1201	686	7	signs	sign	NNS
cord-022561-rv5j1201	686	8	of	of	IN
cord-022561-rv5j1201	686	9	multisystemic	multisystemic	JJ
cord-022561-rv5j1201	686	10	infection	infection	NN
cord-022561-rv5j1201	686	11	and	and	CC
cord-022561-rv5j1201	686	12	hemorrhage	hemorrhage	NN
cord-022561-rv5j1201	686	13	due	due	IN
cord-022561-rv5j1201	686	14	to	to	IN
cord-022561-rv5j1201	686	15	severe	severe	JJ
cord-022561-rv5j1201	686	16	neutropenia	neutropenia	NN
cord-022561-rv5j1201	686	17	and	and	CC
cord-022561-rv5j1201	686	18	thrombocytopenia	thrombocytopenia	NN
cord-022561-rv5j1201	686	19	,	,	,
cord-022561-rv5j1201	686	20	respectively	respectively	RB
cord-022561-rv5j1201	686	21	.	.	.
cord-022561-rv5j1201	687	1	Severe	severe	JJ
cord-022561-rv5j1201	687	2	neutropenia	neutropenia	NN
cord-022561-rv5j1201	687	3	typically	typically	RB
cord-022561-rv5j1201	687	4	develops	develop	VBZ
cord-022561-rv5j1201	687	5	within	within	IN
cord-022561-rv5j1201	687	6	1	1	CD
cord-022561-rv5j1201	687	7	week	week	NN
cord-022561-rv5j1201	687	8	of	of	IN
cord-022561-rv5j1201	687	9	an	an	DT
cord-022561-rv5j1201	687	10	acute	acute	JJ
cord-022561-rv5j1201	687	11	insult	insult	NN
cord-022561-rv5j1201	687	12	to	to	IN
cord-022561-rv5j1201	687	13	the	the	DT
cord-022561-rv5j1201	687	14	bone	bone	NN
cord-022561-rv5j1201	687	15	marrow	marrow	NN
cord-022561-rv5j1201	687	16	,	,	,
cord-022561-rv5j1201	687	17	and	and	CC
cord-022561-rv5j1201	687	18	severe	severe	JJ
cord-022561-rv5j1201	687	19	thrombocytopenia	thrombocytopenia	NN
cord-022561-rv5j1201	687	20	occurs	occur	VBZ
cord-022561-rv5j1201	687	21	in	in	IN
cord-022561-rv5j1201	687	22	the	the	DT
cord-022561-rv5j1201	687	23	second	second	JJ
cord-022561-rv5j1201	687	24	week	week	NN
cord-022561-rv5j1201	687	25	.	.	.
cord-022561-rv5j1201	688	1	This	this	DT
cord-022561-rv5j1201	688	2	sequence	sequence	NN
cord-022561-rv5j1201	688	3	is	be	VBZ
cord-022561-rv5j1201	688	4	a	a	DT
cord-022561-rv5j1201	688	5	result	result	NN
cord-022561-rv5j1201	688	6	of	of	IN
cord-022561-rv5j1201	688	7	the	the	DT
cord-022561-rv5j1201	688	8	circulating	circulate	VBG
cord-022561-rv5j1201	688	9	life	life	NN
cord-022561-rv5j1201	688	10	spans	span	NNS
cord-022561-rv5j1201	688	11	of	of	IN
cord-022561-rv5j1201	688	12	each	each	DT
cord-022561-rv5j1201	688	13	cell	cell	NN
cord-022561-rv5j1201	688	14	type	type	NN
cord-022561-rv5j1201	688	15	;	;	:
cord-022561-rv5j1201	688	16	in	in	IN
cord-022561-rv5j1201	688	17	health	health	NN
cord-022561-rv5j1201	688	18	,	,	,
cord-022561-rv5j1201	688	19	neutrophils	neutrophil	NNS
cord-022561-rv5j1201	688	20	have	have	VBP
cord-022561-rv5j1201	688	21	a	a	DT
cord-022561-rv5j1201	688	22	blood	blood	NN
cord-022561-rv5j1201	688	23	half	half	JJ
cord-022561-rv5j1201	688	24	-	-	HYPH
cord-022561-rv5j1201	688	25	life	life	NN
cord-022561-rv5j1201	688	26	of	of	IN
cord-022561-rv5j1201	688	27	5	5	CD
cord-022561-rv5j1201	688	28	to	to	TO
cord-022561-rv5j1201	688	29	10	10	CD
cord-022561-rv5j1201	688	30	hours	hour	NNS
cord-022561-rv5j1201	688	31	,	,	,
cord-022561-rv5j1201	688	32	whereas	whereas	IN
cord-022561-rv5j1201	688	33	platelets	platelet	NNS
cord-022561-rv5j1201	688	34	circulate	circulate	VBP
cord-022561-rv5j1201	688	35	for	for	IN
cord-022561-rv5j1201	688	36	5	5	CD
cord-022561-rv5j1201	688	37	to	to	TO
cord-022561-rv5j1201	688	38	10	10	CD
cord-022561-rv5j1201	688	39	days	day	NNS
cord-022561-rv5j1201	688	40	.	.	.
cord-022561-rv5j1201	689	1	The	the	DT
cord-022561-rv5j1201	689	2	development	development	NN
cord-022561-rv5j1201	689	3	of	of	IN
cord-022561-rv5j1201	689	4	signs	sign	NNS
cord-022561-rv5j1201	689	5	of	of	IN
cord-022561-rv5j1201	689	6	anemia	anemia	NN
cord-022561-rv5j1201	689	7	,	,	,
cord-022561-rv5j1201	689	8	such	such	JJ
cord-022561-rv5j1201	689	9	as	as	IN
cord-022561-rv5j1201	689	10	pale	pale	JJ
cord-022561-rv5j1201	689	11	mucous	mucous	JJ
cord-022561-rv5j1201	689	12	membranes	membrane	NNS
cord-022561-rv5j1201	689	13	,	,	,
cord-022561-rv5j1201	689	14	is	be	VBZ
cord-022561-rv5j1201	689	15	more	more	RBR
cord-022561-rv5j1201	689	16	variable	variable	JJ
cord-022561-rv5j1201	689	17	.	.	.
cord-022561-rv5j1201	690	1	The	the	DT
cord-022561-rv5j1201	690	2	presence	presence	NN
cord-022561-rv5j1201	690	3	and	and	CC
cord-022561-rv5j1201	690	4	severity	severity	NN
cord-022561-rv5j1201	690	5	of	of	IN
cord-022561-rv5j1201	690	6	anemia	anemia	NN
cord-022561-rv5j1201	690	7	depends	depend	VBZ
cord-022561-rv5j1201	690	8	on	on	IN
cord-022561-rv5j1201	690	9	how	how	WRB
cord-022561-rv5j1201	690	10	rapidly	rapidly	RB
cord-022561-rv5j1201	690	11	the	the	DT
cord-022561-rv5j1201	690	12	marrow	marrow	NN
cord-022561-rv5j1201	690	13	recovers	recover	VBZ
cord-022561-rv5j1201	690	14	from	from	IN
cord-022561-rv5j1201	690	15	the	the	DT
cord-022561-rv5j1201	690	16	insult	insult	NN
cord-022561-rv5j1201	690	17	and	and	CC
cord-022561-rv5j1201	690	18	the	the	DT
cord-022561-rv5j1201	690	19	erythrocyte	erythrocyte	NN
cord-022561-rv5j1201	690	20	life	life	NN
cord-022561-rv5j1201	690	21	span	span	NN
cord-022561-rv5j1201	690	22	of	of	IN
cord-022561-rv5j1201	690	23	the	the	DT
cord-022561-rv5j1201	690	24	particular	particular	JJ
cord-022561-rv5j1201	690	25	species	specie	NNS
cord-022561-rv5j1201	690	26	.	.	.
cord-022561-rv5j1201	691	1	Microscopically	microscopically	RB
cord-022561-rv5j1201	691	2	,	,	,
cord-022561-rv5j1201	691	3	bone	bone	NN
cord-022561-rv5j1201	691	4	marrow	marrow	NN
cord-022561-rv5j1201	691	5	is	be	VBZ
cord-022561-rv5j1201	691	6	hypocellular	hypocellular	NN
cord-022561-rv5j1201	691	7	with	with	IN
cord-022561-rv5j1201	691	8	markedly	markedly	RB
cord-022561-rv5j1201	691	9	reduced	reduce	VBN
cord-022561-rv5j1201	691	10	hematopoietic	hematopoietic	JJ
cord-022561-rv5j1201	691	11	cells	cell	NNS
cord-022561-rv5j1201	691	12	.	.	.
cord-022561-rv5j1201	692	1	Hematopoietic	hematopoietic	JJ
cord-022561-rv5j1201	692	2	cells	cell	NNS
cord-022561-rv5j1201	692	3	are	be	VBP
cord-022561-rv5j1201	692	4	replaced	replace	VBN
cord-022561-rv5j1201	692	5	with	with	IN
cord-022561-rv5j1201	692	6	adipose	adipose	JJ
cord-022561-rv5j1201	692	7	tissue	tissue	NN
cord-022561-rv5j1201	692	8	,	,	,
cord-022561-rv5j1201	692	9	and	and	CC
cord-022561-rv5j1201	692	10	there	there	EX
cord-022561-rv5j1201	692	11	is	be	VBZ
cord-022561-rv5j1201	692	12	a	a	DT
cord-022561-rv5j1201	692	13	variable	variable	JJ
cord-022561-rv5j1201	692	14	inflammatory	inflammatory	JJ
cord-022561-rv5j1201	692	15	infiltrate	infiltrate	NN
cord-022561-rv5j1201	692	16	of	of	IN
cord-022561-rv5j1201	692	17	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	692	18	,	,	,
cord-022561-rv5j1201	692	19	plasma	plasma	NN
cord-022561-rv5j1201	692	20	cells	cell	NNS
cord-022561-rv5j1201	692	21	,	,	,
cord-022561-rv5j1201	692	22	and	and	CC
cord-022561-rv5j1201	692	23	macrophages	macrophage	NNS
cord-022561-rv5j1201	692	24	.	.	.
cord-022561-rv5j1201	693	1	In	in	IN
cord-022561-rv5j1201	693	2	addition	addition	NN
cord-022561-rv5j1201	693	3	,	,	,
cord-022561-rv5j1201	693	4	there	there	EX
cord-022561-rv5j1201	693	5	may	may	MD
cord-022561-rv5j1201	693	6	be	be	VB
cord-022561-rv5j1201	693	7	necrosis	necrosis	NN
cord-022561-rv5j1201	693	8	,	,	,
cord-022561-rv5j1201	693	9	hematopoietic	hematopoietic	JJ
cord-022561-rv5j1201	693	10	cell	cell	NN
cord-022561-rv5j1201	693	11	apoptosis	apoptosis	NN
cord-022561-rv5j1201	693	12	,	,	,
cord-022561-rv5j1201	693	13	and	and	CC
cord-022561-rv5j1201	693	14	an	an	DT
cord-022561-rv5j1201	693	15	increase	increase	NN
cord-022561-rv5j1201	693	16	in	in	IN
cord-022561-rv5j1201	693	17	phagocytic	phagocytic	JJ
cord-022561-rv5j1201	693	18	macrophages	macrophage	NNS
cord-022561-rv5j1201	693	19	.	.	.
cord-022561-rv5j1201	694	1	Fig	Fig	NNP
cord-022561-rv5j1201	694	2	.	.	NNP
cord-022561-rv5j1201	694	3	13	13	CD
cord-022561-rv5j1201	694	4	-21	-21	NN
cord-022561-rv5j1201	694	5	shows	show	VBZ
cord-022561-rv5j1201	694	6	bone	bone	NN
cord-022561-rv5j1201	694	7	marrow	marrow	NN
cord-022561-rv5j1201	694	8	aspirates	aspirate	NNS
cord-022561-rv5j1201	694	9	from	from	IN
cord-022561-rv5j1201	694	10	a	a	DT
cord-022561-rv5j1201	694	11	dog	dog	NN
cord-022561-rv5j1201	694	12	with	with	IN
cord-022561-rv5j1201	694	13	pancytopenia	pancytopenia	NNP
cord-022561-rv5j1201	694	14	from	from	IN
cord-022561-rv5j1201	694	15	acute	acute	JJ
cord-022561-rv5j1201	694	16	5-fluorouracil	5-fluorouracil	CD
cord-022561-rv5j1201	694	17	toxicosis	toxicosis	NN
cord-022561-rv5j1201	694	18	,	,	,
cord-022561-rv5j1201	694	19	before	before	IN
cord-022561-rv5j1201	694	20	and	and	CC
cord-022561-rv5j1201	694	21	during	during	IN
cord-022561-rv5j1201	694	22	recovery	recovery	NN
cord-022561-rv5j1201	694	23	.	.	.
cord-022561-rv5j1201	695	1	Many	many	JJ
cord-022561-rv5j1201	695	2	inherited	inherit	VBN
cord-022561-rv5j1201	695	3	or	or	CC
cord-022561-rv5j1201	695	4	presumably	presumably	RB
cord-022561-rv5j1201	695	5	inherited	inherit	VBN
cord-022561-rv5j1201	695	6	disorders	disorder	NNS
cord-022561-rv5j1201	695	7	of	of	IN
cord-022561-rv5j1201	695	8	blood	blood	NN
cord-022561-rv5j1201	695	9	cells	cell	NNS
cord-022561-rv5j1201	695	10	have	have	VBP
cord-022561-rv5j1201	695	11	been	be	VBN
cord-022561-rv5j1201	695	12	recognized	recognize	VBN
cord-022561-rv5j1201	695	13	in	in	IN
cord-022561-rv5j1201	695	14	domestic	domestic	JJ
cord-022561-rv5j1201	695	15	animals	animal	NNS
cord-022561-rv5j1201	695	16	,	,	,
cord-022561-rv5j1201	695	17	including	include	VBG
cord-022561-rv5j1201	695	18	rare	rare	JJ
cord-022561-rv5j1201	695	19	or	or	CC
cord-022561-rv5j1201	695	20	sporadic	sporadic	JJ
cord-022561-rv5j1201	695	21	cases	case	NNS
cord-022561-rv5j1201	695	22	and	and	CC
cord-022561-rv5j1201	695	23	conditions	condition	NNS
cord-022561-rv5j1201	695	24	that	that	WDT
cord-022561-rv5j1201	695	25	are	be	VBP
cord-022561-rv5j1201	695	26	of	of	IN
cord-022561-rv5j1201	695	27	questionable	questionable	JJ
cord-022561-rv5j1201	695	28	clinical	clinical	JJ
cord-022561-rv5j1201	695	29	relevance	relevance	NN
cord-022561-rv5j1201	695	30	.	.	.
cord-022561-rv5j1201	696	1	This	this	DT
cord-022561-rv5j1201	696	2	section	section	NN
cord-022561-rv5j1201	696	3	and	and	CC
cord-022561-rv5j1201	696	4	the	the	DT
cord-022561-rv5j1201	696	5	later	later	JJ
cord-022561-rv5j1201	696	6	sections	section	NNS
cord-022561-rv5j1201	696	7	covering	cover	VBG
cord-022561-rv5j1201	696	8	species	species	NN
cord-022561-rv5j1201	696	9	-	-	HYPH
cord-022561-rv5j1201	696	10	specific	specific	JJ
cord-022561-rv5j1201	696	11	disorders	disorder	NNS
cord-022561-rv5j1201	696	12	are	be	VBP
cord-022561-rv5j1201	696	13	Invading	invade	VBG
cord-022561-rv5j1201	696	14	cells	cell	NNS
cord-022561-rv5j1201	696	15	or	or	CC
cord-022561-rv5j1201	696	16	microorganism	microorganism	NN
cord-022561-rv5j1201	696	17	gain	gain	VB
cord-022561-rv5j1201	696	18	access	access	NN
cord-022561-rv5j1201	696	19	to	to	IN
cord-022561-rv5j1201	696	20	the	the	DT
cord-022561-rv5j1201	696	21	bone	bone	NN
cord-022561-rv5j1201	696	22	marrow	marrow	NN
cord-022561-rv5j1201	696	23	or	or	CC
cord-022561-rv5j1201	696	24	blood	blood	NN
cord-022561-rv5j1201	696	25	circulation	circulation	NN
cord-022561-rv5j1201	696	26	either	either	CC
cord-022561-rv5j1201	696	27	hematogenously	hematogenously	NN
cord-022561-rv5j1201	696	28	or	or	CC
cord-022561-rv5j1201	696	29	by	by	IN
cord-022561-rv5j1201	696	30	trauma	trauma	NN
cord-022561-rv5j1201	696	31	.	.	.
cord-022561-rv5j1201	697	1	Trauma	trauma	NN
cord-022561-rv5j1201	697	2	may	may	MD
cord-022561-rv5j1201	697	3	be	be	VB
cord-022561-rv5j1201	697	4	as	as	RB
cord-022561-rv5j1201	697	5	obvious	obvious	JJ
cord-022561-rv5j1201	697	6	as	as	IN
cord-022561-rv5j1201	697	7	a	a	DT
cord-022561-rv5j1201	697	8	gaping	gape	VBG
cord-022561-rv5j1201	697	9	wound	wound	NN
cord-022561-rv5j1201	697	10	or	or	CC
cord-022561-rv5j1201	697	11	as	as	RB
cord-022561-rv5j1201	697	12	subtle	subtle	JJ
cord-022561-rv5j1201	697	13	as	as	IN
cord-022561-rv5j1201	697	14	the	the	DT
cord-022561-rv5j1201	697	15	bite	bite	NN
cord-022561-rv5j1201	697	16	of	of	IN
cord-022561-rv5j1201	697	17	an	an	DT
cord-022561-rv5j1201	697	18	insect	insect	NN
cord-022561-rv5j1201	697	19	.	.	.
cord-022561-rv5j1201	698	1	Portals	portal	NNS
cord-022561-rv5j1201	698	2	of	of	IN
cord-022561-rv5j1201	698	3	entry	entry	NN
cord-022561-rv5j1201	698	4	for	for	IN
cord-022561-rv5j1201	698	5	the	the	DT
cord-022561-rv5j1201	698	6	bone	bone	NN
cord-022561-rv5j1201	698	7	marrow	marrow	NN
cord-022561-rv5j1201	698	8	are	be	VBP
cord-022561-rv5j1201	698	9	summarized	summarize	VBN
cord-022561-rv5j1201	698	10	in	in	IN
cord-022561-rv5j1201	698	11	Box	Box	NNP
cord-022561-rv5j1201	698	12	13	13	CD
cord-022561-rv5j1201	698	13	-	-	SYM
cord-022561-rv5j1201	698	14	3	3	CD
cord-022561-rv5j1201	698	15	.	.	.
cord-022561-rv5j1201	699	1	Diseases	disease	NNS
cord-022561-rv5j1201	699	2	that	that	WDT
cord-022561-rv5j1201	699	3	arise	arise	VBP
cord-022561-rv5j1201	699	4	from	from	IN
cord-022561-rv5j1201	699	5	the	the	DT
cord-022561-rv5j1201	699	6	bone	bone	NN
cord-022561-rv5j1201	699	7	marrow	marrow	NN
cord-022561-rv5j1201	699	8	,	,	,
cord-022561-rv5j1201	699	9	such	such	JJ
cord-022561-rv5j1201	699	10	as	as	IN
cord-022561-rv5j1201	699	11	leukemia	leukemia	NN
cord-022561-rv5j1201	699	12	,	,	,
cord-022561-rv5j1201	699	13	typically	typically	RB
cord-022561-rv5j1201	699	14	spread	spread	VBN
cord-022561-rv5j1201	699	15	to	to	IN
cord-022561-rv5j1201	699	16	other	other	JJ
cord-022561-rv5j1201	699	17	tissues	tissue	NNS
cord-022561-rv5j1201	699	18	hematogenously	hematogenously	RB
cord-022561-rv5j1201	699	19	.	.	.
cord-022561-rv5j1201	700	1	The	the	DT
cord-022561-rv5j1201	700	2	bone	bone	NN
cord-022561-rv5j1201	700	3	marrow	marrow	NN
cord-022561-rv5j1201	700	4	is	be	VBZ
cord-022561-rv5j1201	700	5	encased	encase	VBN
cord-022561-rv5j1201	700	6	by	by	IN
cord-022561-rv5j1201	700	7	a	a	DT
cord-022561-rv5j1201	700	8	protective	protective	JJ
cord-022561-rv5j1201	700	9	shell	shell	NN
cord-022561-rv5j1201	700	10	of	of	IN
cord-022561-rv5j1201	700	11	cortical	cortical	JJ
cord-022561-rv5j1201	700	12	bone	bone	NN
cord-022561-rv5j1201	700	13	,	,	,
cord-022561-rv5j1201	700	14	and	and	CC
cord-022561-rv5j1201	700	15	blood	blood	NN
cord-022561-rv5j1201	700	16	supply	supply	NN
cord-022561-rv5j1201	700	17	to	to	IN
cord-022561-rv5j1201	700	18	the	the	DT
cord-022561-rv5j1201	700	19	marrow	marrow	NN
cord-022561-rv5j1201	700	20	provides	provide	VBZ
cord-022561-rv5j1201	700	21	access	access	NN
cord-022561-rv5j1201	700	22	to	to	IN
cord-022561-rv5j1201	700	23	systemic	systemic	JJ
cord-022561-rv5j1201	700	24	humoral	humoral	JJ
cord-022561-rv5j1201	700	25	and	and	CC
cord-022561-rv5j1201	700	26	cellular	cellular	JJ
cord-022561-rv5j1201	700	27	defenses	defense	NNS
cord-022561-rv5j1201	700	28	.	.	.
cord-022561-rv5j1201	701	1	Of	of	RB
cord-022561-rv5j1201	701	2	course	course	RB
cord-022561-rv5j1201	701	3	,	,	,
cord-022561-rv5j1201	701	4	leukocytes	leukocyte	VBZ
cord-022561-rv5j1201	701	5	themselves	-PRON-	PRP
cord-022561-rv5j1201	701	6	function	function	VBP
cord-022561-rv5j1201	701	7	as	as	IN
cord-022561-rv5j1201	701	8	an	an	DT
cord-022561-rv5j1201	701	9	essential	essential	JJ
cord-022561-rv5j1201	701	10	part	part	NN
cord-022561-rv5j1201	701	11	of	of	IN
cord-022561-rv5j1201	701	12	inflammation	inflammation	NN
cord-022561-rv5j1201	701	13	and	and	CC
cord-022561-rv5j1201	701	14	immune	immune	JJ
cord-022561-rv5j1201	701	15	function	function	NN
cord-022561-rv5j1201	701	16	,	,	,
cord-022561-rv5j1201	701	17	as	as	IN
cord-022561-rv5j1201	701	18	discussed	discuss	VBN
cord-022561-rv5j1201	701	19	briefly	briefly	RB
cord-022561-rv5j1201	701	20	in	in	IN
cord-022561-rv5j1201	701	21	the	the	DT
cord-022561-rv5j1201	701	22	section	section	NN
cord-022561-rv5j1201	701	23	on	on	IN
cord-022561-rv5j1201	701	24	Granulopoiesis	Granulopoiesis	NNP
cord-022561-rv5j1201	701	25	and	and	CC
cord-022561-rv5j1201	701	26	Monocytopoiesis	Monocytopoiesis	NNP
cord-022561-rv5j1201	701	27	(	(	-LRB-
cord-022561-rv5j1201	701	28	Myelopoiesis	Myelopoiesis	NNP
cord-022561-rv5j1201	701	29	)	)	-RRB-
cord-022561-rv5j1201	701	30	and	and	CC
cord-022561-rv5j1201	701	31	in	in	IN
cord-022561-rv5j1201	701	32	greater	great	JJR
cord-022561-rv5j1201	701	33	detail	detail	NN
cord-022561-rv5j1201	701	34	in	in	IN
cord-022561-rv5j1201	701	35	Chapters	chapter	NNS
cord-022561-rv5j1201	701	36	3	3	CD
cord-022561-rv5j1201	701	37	and	and	CC
cord-022561-rv5j1201	701	38	5	5	CD
cord-022561-rv5j1201	701	39	.	.	.
cord-022561-rv5j1201	702	1	Biochemical	biochemical	JJ
cord-022561-rv5j1201	702	2	steps	step	NNS
cord-022561-rv5j1201	702	3	in	in	IN
cord-022561-rv5j1201	702	4	the	the	DT
cord-022561-rv5j1201	702	5	glycolytic	glycolytic	JJ
cord-022561-rv5j1201	702	6	pathway	pathway	NN
cord-022561-rv5j1201	702	7	or	or	CC
cord-022561-rv5j1201	702	8	linked	link	VBN
cord-022561-rv5j1201	702	9	to	to	IN
cord-022561-rv5j1201	702	10	it	-PRON-	PRP
cord-022561-rv5j1201	702	11	generate	generate	VB
cord-022561-rv5j1201	702	12	antioxidant	antioxidant	JJ
cord-022561-rv5j1201	702	13	molecules	molecule	NNS
cord-022561-rv5j1201	702	14	that	that	WDT
cord-022561-rv5j1201	702	15	enable	enable	VBP
cord-022561-rv5j1201	702	16	erythrocytes	erythrocyte	NNS
cord-022561-rv5j1201	702	17	to	to	TO
cord-022561-rv5j1201	702	18	withstand	withstand	VB
cord-022561-rv5j1201	702	19	oxidative	oxidative	JJ
cord-022561-rv5j1201	702	20	insults	insult	NNS
cord-022561-rv5j1201	702	21	throughout	throughout	IN
cord-022561-rv5j1201	702	22	their	-PRON-	PRP$
cord-022561-rv5j1201	702	23	many	many	JJ
cord-022561-rv5j1201	702	24	days	day	NNS
cord-022561-rv5j1201	702	25	in	in	IN
cord-022561-rv5j1201	702	26	circulation	circulation	NN
cord-022561-rv5j1201	702	27	.	.	.
cord-022561-rv5j1201	703	1	In	in	IN
cord-022561-rv5j1201	703	2	addition	addition	NN
cord-022561-rv5j1201	703	3	to	to	IN
cord-022561-rv5j1201	703	4	producing	produce	VBG
cord-022561-rv5j1201	703	5	energy	energy	NN
cord-022561-rv5j1201	703	6	in	in	IN
cord-022561-rv5j1201	703	7	the	the	DT
cord-022561-rv5j1201	703	8	form	form	NN
cord-022561-rv5j1201	703	9	of	of	IN
cord-022561-rv5j1201	703	10	adenosine	adenosine	NN
cord-022561-rv5j1201	703	11	triphosphate	triphosphate	NN
cord-022561-rv5j1201	703	12	(	(	-LRB-
cord-022561-rv5j1201	703	13	ATP	ATP	NNP
cord-022561-rv5j1201	703	14	)	)	-RRB-
cord-022561-rv5j1201	703	15	,	,	,
cord-022561-rv5j1201	703	16	glycolysis	glycolysis	NN
cord-022561-rv5j1201	703	17	generates	generate	VBZ
cord-022561-rv5j1201	703	18	NADH	NADH	NNP
cord-022561-rv5j1201	703	19	,	,	,
cord-022561-rv5j1201	703	20	which	which	WDT
cord-022561-rv5j1201	703	21	helps	help	VBZ
cord-022561-rv5j1201	703	22	convert	convert	VB
cord-022561-rv5j1201	703	23	the	the	DT
cord-022561-rv5j1201	703	24	oxidized	oxidize	VBN
cord-022561-rv5j1201	703	25	,	,	,
cord-022561-rv5j1201	703	26	nonfunctional	nonfunctional	JJ
cord-022561-rv5j1201	703	27	form	form	NN
cord-022561-rv5j1201	703	28	of	of	IN
cord-022561-rv5j1201	703	29	hemoglobin	hemoglobin	NN
cord-022561-rv5j1201	703	30	,	,	,
cord-022561-rv5j1201	703	31	known	know	VBN
cord-022561-rv5j1201	703	32	as	as	IN
cord-022561-rv5j1201	703	33	methemoglobin	methemoglobin	NNP
cord-022561-rv5j1201	703	34	,	,	,
cord-022561-rv5j1201	703	35	back	back	RB
cord-022561-rv5j1201	703	36	to	to	IN
cord-022561-rv5j1201	703	37	its	-PRON-	PRP$
cord-022561-rv5j1201	703	38	active	active	JJ
cord-022561-rv5j1201	703	39	,	,	,
cord-022561-rv5j1201	703	40	reduced	reduced	JJ
cord-022561-rv5j1201	703	41	state	state	NN
cord-022561-rv5j1201	703	42	.	.	.
cord-022561-rv5j1201	704	1	Another	another	DT
cord-022561-rv5j1201	704	2	antioxidant	antioxidant	JJ
cord-022561-rv5j1201	704	3	erythrocyte	erythrocyte	NN
cord-022561-rv5j1201	704	4	metabolic	metabolic	JJ
cord-022561-rv5j1201	704	5	pathway	pathway	NN
cord-022561-rv5j1201	704	6	,	,	,
cord-022561-rv5j1201	704	7	the	the	DT
cord-022561-rv5j1201	704	8	pentose	pentose	JJ
cord-022561-rv5j1201	704	9	shunt	shunt	NN
cord-022561-rv5j1201	704	10	or	or	CC
cord-022561-rv5j1201	704	11	hexose	hexose	NN
cord-022561-rv5j1201	704	12	Uremia	Uremia	NNP
cord-022561-rv5j1201	704	13	Antiplatelet	Antiplatelet	NNP
cord-022561-rv5j1201	704	14	antibodies	antibody	NNS
cord-022561-rv5j1201	704	15	(	(	-LRB-
cord-022561-rv5j1201	704	16	also	also	RB
cord-022561-rv5j1201	704	17	cause	cause	VB
cord-022561-rv5j1201	704	18	immune	immune	NN
cord-022561-rv5j1201	704	19	-	-	HYPH
cord-022561-rv5j1201	704	20	mediated	mediate	VBN
cord-022561-rv5j1201	704	21	thrombocytopenia	thrombocytopenia	NN
cord-022561-rv5j1201	704	22	)	)	-RRB-
cord-022561-rv5j1201	705	1	Infection	infection	NN
cord-022561-rv5j1201	705	2	(	(	-LRB-
cord-022561-rv5j1201	705	3	BVDV	BVDV	NNP
cord-022561-rv5j1201	705	4	,	,	,
cord-022561-rv5j1201	705	5	FeLV	FeLV	NNP
cord-022561-rv5j1201	705	6	)	)	-RRB-
cord-022561-rv5j1201	706	1	Hyperglobulinemia	Hyperglobulinemia	NNP
cord-022561-rv5j1201	706	2	Increased	increase	VBN
cord-022561-rv5j1201	706	3	fibrinolytic	fibrinolytic	JJ
cord-022561-rv5j1201	706	4	products	product	NNS
cord-022561-rv5j1201	706	5	Hypoammonemia	Hypoammonemia	NNP
cord-022561-rv5j1201	706	6	Snake	Snake	NNP
cord-022561-rv5j1201	706	7	envenomation	envenomation	NN
cord-022561-rv5j1201	706	8	Platelet	platelet	NN
cord-022561-rv5j1201	706	9	inhibitors	inhibitor	NNS
cord-022561-rv5j1201	706	10	NSAIDs	nsaids	JJ
cord-022561-rv5j1201	706	11	-	-	HYPH
cord-022561-rv5j1201	706	12	irreversible	irreversible	JJ
cord-022561-rv5j1201	706	13	(	(	-LRB-
cord-022561-rv5j1201	706	14	aspirin	aspirin	NN
cord-022561-rv5j1201	706	15	)	)	-RRB-
cord-022561-rv5j1201	706	16	or	or	CC
cord-022561-rv5j1201	706	17	reversible	reversible	JJ
cord-022561-rv5j1201	706	18	inhibition	inhibition	NN
cord-022561-rv5j1201	706	19	of	of	IN
cord-022561-rv5j1201	706	20	cyclooxygenase	cyclooxygenase	JJ
cord-022561-rv5j1201	706	21	Colloidal	colloidal	NN
cord-022561-rv5j1201	706	22	plasma	plasma	NN
cord-022561-rv5j1201	706	23	expanders	expander	NNS
cord-022561-rv5j1201	706	24	(	(	-LRB-
cord-022561-rv5j1201	706	25	e.g.	e.g.	RB
cord-022561-rv5j1201	706	26	,	,	,
cord-022561-rv5j1201	706	27	hydroxyethyl	hydroxyethyl	NN
cord-022561-rv5j1201	706	28	starch	starch	NN
cord-022561-rv5j1201	706	29	)	)	-RRB-
cord-022561-rv5j1201	707	1	Other	other	JJ
cord-022561-rv5j1201	707	2	drugs	drug	NNS
cord-022561-rv5j1201	707	3	and	and	CC
cord-022561-rv5j1201	707	4	exogenous	exogenous	JJ
cord-022561-rv5j1201	707	5	agents	agent	NNS
cord-022561-rv5j1201	707	6	(	(	-LRB-
cord-022561-rv5j1201	707	7	many	many	JJ
cord-022561-rv5j1201	707	8	)	)	-RRB-
cord-022561-rv5j1201	707	9	 	 	_SP
cord-022561-rv5j1201	707	10	Hematogenously	Hematogenously	NNP
cord-022561-rv5j1201	707	11	Direct	direct	JJ
cord-022561-rv5j1201	707	12	penetration	penetration	NN
cord-022561-rv5j1201	707	13	(	(	-LRB-
cord-022561-rv5j1201	707	14	trauma	trauma	NN
cord-022561-rv5j1201	707	15	)	)	-RRB-
cord-022561-rv5j1201	707	16	including	include	VBG
cord-022561-rv5j1201	707	17	hypercellular	hypercellular	NNP
cord-022561-rv5j1201	707	18	glomeruli	glomerulus	NNS
cord-022561-rv5j1201	707	19	,	,	,
cord-022561-rv5j1201	707	20	thickened	thicken	VBD
cord-022561-rv5j1201	707	21	glomerular	glomerular	JJ
cord-022561-rv5j1201	707	22	and	and	CC
cord-022561-rv5j1201	707	23	tubular	tubular	JJ
cord-022561-rv5j1201	707	24	basement	basement	NN
cord-022561-rv5j1201	707	25	membranes	membrane	NNS
cord-022561-rv5j1201	707	26	,	,	,
cord-022561-rv5j1201	707	27	and	and	CC
cord-022561-rv5j1201	707	28	tubular	tubular	JJ
cord-022561-rv5j1201	707	29	epithelial	epithelial	JJ
cord-022561-rv5j1201	707	30	lipidosis	lipidosis	NN
cord-022561-rv5j1201	707	31	,	,	,
cord-022561-rv5j1201	707	32	degeneration	degeneration	NN
cord-022561-rv5j1201	707	33	,	,	,
cord-022561-rv5j1201	707	34	and	and	CC
cord-022561-rv5j1201	707	35	necrosis	necrosis	NN
cord-022561-rv5j1201	707	36	.	.	.
cord-022561-rv5j1201	708	1	Other	other	JJ
cord-022561-rv5j1201	708	2	porphyrias	porphyrias	NN
cord-022561-rv5j1201	708	3	have	have	VBP
cord-022561-rv5j1201	708	4	been	be	VBN
cord-022561-rv5j1201	708	5	diagnosed	diagnose	VBN
cord-022561-rv5j1201	708	6	in	in	IN
cord-022561-rv5j1201	708	7	cattle	cattle	NNS
cord-022561-rv5j1201	708	8	,	,	,
cord-022561-rv5j1201	708	9	pigs	pig	NNS
cord-022561-rv5j1201	708	10	,	,	,
cord-022561-rv5j1201	708	11	and	and	CC
cord-022561-rv5j1201	708	12	cats	cat	NNS
cord-022561-rv5j1201	708	13	but	but	CC
cord-022561-rv5j1201	708	14	are	be	VBP
cord-022561-rv5j1201	708	15	not	not	RB
cord-022561-rv5j1201	708	16	known	know	VBN
cord-022561-rv5j1201	708	17	to	to	TO
cord-022561-rv5j1201	708	18	cause	cause	VB
cord-022561-rv5j1201	708	19	hemolytic	hemolytic	JJ
cord-022561-rv5j1201	708	20	anemia	anemia	NN
cord-022561-rv5j1201	708	21	.	.	.
cord-022561-rv5j1201	709	1	Pyruvate	Pyruvate	NNP
cord-022561-rv5j1201	709	2	Kinase	Kinase	NNP
cord-022561-rv5j1201	709	3	Deficiency	deficiency	NN
cord-022561-rv5j1201	709	4	.	.	.
cord-022561-rv5j1201	710	1	Pyruvate	pyruvate	NN
cord-022561-rv5j1201	710	2	kinase	kinase	NN
cord-022561-rv5j1201	710	3	(	(	-LRB-
cord-022561-rv5j1201	710	4	PK	PK	NNP
cord-022561-rv5j1201	710	5	)	)	-RRB-
cord-022561-rv5j1201	710	6	deficiency	deficiency	NN
cord-022561-rv5j1201	710	7	is	be	VBZ
cord-022561-rv5j1201	710	8	an	an	DT
cord-022561-rv5j1201	710	9	inherited	inherit	VBN
cord-022561-rv5j1201	710	10	autosomal	autosomal	JJ
cord-022561-rv5j1201	710	11	recessive	recessive	JJ
cord-022561-rv5j1201	710	12	condition	condition	NN
cord-022561-rv5j1201	710	13	due	due	IN
cord-022561-rv5j1201	710	14	to	to	IN
cord-022561-rv5j1201	710	15	a	a	DT
cord-022561-rv5j1201	710	16	defective	defective	JJ
cord-022561-rv5j1201	710	17	R	r	NN
cord-022561-rv5j1201	710	18	-	-	HYPH
cord-022561-rv5j1201	710	19	type	type	NN
cord-022561-rv5j1201	710	20	PK	PK	NNP
cord-022561-rv5j1201	710	21	isoenzyme	isoenzyme	NNS
cord-022561-rv5j1201	710	22	that	that	WDT
cord-022561-rv5j1201	710	23	is	be	VBZ
cord-022561-rv5j1201	710	24	normally	normally	RB
cord-022561-rv5j1201	710	25	present	present	JJ
cord-022561-rv5j1201	710	26	in	in	IN
cord-022561-rv5j1201	710	27	high	high	JJ
cord-022561-rv5j1201	710	28	concentrations	concentration	NNS
cord-022561-rv5j1201	710	29	in	in	IN
cord-022561-rv5j1201	710	30	mature	mature	JJ
cord-022561-rv5j1201	710	31	erythrocytes	erythrocyte	NNS
cord-022561-rv5j1201	710	32	.	.	.
cord-022561-rv5j1201	711	1	To	to	TO
cord-022561-rv5j1201	711	2	compensate	compensate	VB
cord-022561-rv5j1201	711	3	for	for	IN
cord-022561-rv5j1201	711	4	this	this	DT
cord-022561-rv5j1201	711	5	deficiency	deficiency	NN
cord-022561-rv5j1201	711	6	,	,	,
cord-022561-rv5j1201	711	7	there	there	EX
cord-022561-rv5j1201	711	8	is	be	VBZ
cord-022561-rv5j1201	711	9	persistence	persistence	NN
cord-022561-rv5j1201	711	10	of	of	IN
cord-022561-rv5j1201	711	11	the	the	DT
cord-022561-rv5j1201	711	12	M2-type	M2-type	NNS
cord-022561-rv5j1201	711	13	PK	PK	NNP
cord-022561-rv5j1201	711	14	isoenzyme	isoenzyme	NNP
cord-022561-rv5j1201	711	15	,	,	,
cord-022561-rv5j1201	711	16	which	which	WDT
cord-022561-rv5j1201	711	17	is	be	VBZ
cord-022561-rv5j1201	711	18	less	less	RBR
cord-022561-rv5j1201	711	19	stable	stable	JJ
cord-022561-rv5j1201	711	20	than	than	IN
cord-022561-rv5j1201	711	21	the	the	DT
cord-022561-rv5j1201	711	22	R	r	NN
cord-022561-rv5j1201	711	23	-	-	HYPH
cord-022561-rv5j1201	711	24	type	type	NN
cord-022561-rv5j1201	711	25	isoenzyme	isoenzyme	NNS
cord-022561-rv5j1201	711	26	.	.	.
cord-022561-rv5j1201	712	1	The	the	DT
cord-022561-rv5j1201	712	2	disease	disease	NN
cord-022561-rv5j1201	712	3	is	be	VBZ
cord-022561-rv5j1201	712	4	reported	report	VBN
cord-022561-rv5j1201	712	5	in	in	IN
cord-022561-rv5j1201	712	6	many	many	JJ
cord-022561-rv5j1201	712	7	dog	dog	NN
cord-022561-rv5j1201	712	8	breeds	breed	NNS
cord-022561-rv5j1201	712	9	and	and	CC
cord-022561-rv5j1201	712	10	fewer	few	JJR
cord-022561-rv5j1201	712	11	cat	cat	NN
cord-022561-rv5j1201	712	12	breeds	breed	NNS
cord-022561-rv5j1201	712	13	(	(	-LRB-
cord-022561-rv5j1201	712	14	e.g.	e.g.	RB
cord-022561-rv5j1201	712	15	,	,	,
cord-022561-rv5j1201	712	16	Abyssinian	Abyssinian	NNP
cord-022561-rv5j1201	712	17	,	,	,
cord-022561-rv5j1201	712	18	Somali	Somali	NNP
cord-022561-rv5j1201	712	19	,	,	,
cord-022561-rv5j1201	712	20	and	and	CC
cord-022561-rv5j1201	712	21	domestic	domestic	JJ
cord-022561-rv5j1201	712	22	shorthair	shorthair	NN
cord-022561-rv5j1201	712	23	)	)	-RRB-
cord-022561-rv5j1201	712	24	.	.	.
cord-022561-rv5j1201	713	1	Erythrocyte	Erythrocyte	NNP
cord-022561-rv5j1201	713	2	PK	PK	NNP
cord-022561-rv5j1201	713	3	deficiency	deficiency	NN
cord-022561-rv5j1201	713	4	results	result	NNS
cord-022561-rv5j1201	713	5	in	in	IN
cord-022561-rv5j1201	713	6	decreased	decrease	VBN
cord-022561-rv5j1201	713	7	ATP	ATP	NNP
cord-022561-rv5j1201	713	8	production	production	NN
cord-022561-rv5j1201	713	9	and	and	CC
cord-022561-rv5j1201	713	10	shortened	shorten	VBN
cord-022561-rv5j1201	713	11	erythrocyte	erythrocyte	NN
cord-022561-rv5j1201	713	12	life	life	NN
cord-022561-rv5j1201	713	13	spans	span	VBZ
cord-022561-rv5j1201	713	14	.	.	.
cord-022561-rv5j1201	714	1	In	in	IN
cord-022561-rv5j1201	714	2	dogs	dog	NNS
cord-022561-rv5j1201	714	3	the	the	DT
cord-022561-rv5j1201	714	4	hemolytic	hemolytic	JJ
cord-022561-rv5j1201	714	5	anemia	anemia	NN
cord-022561-rv5j1201	714	6	is	be	VBZ
cord-022561-rv5j1201	714	7	typically	typically	RB
cord-022561-rv5j1201	714	8	chronic	chronic	JJ
cord-022561-rv5j1201	714	9	,	,	,
cord-022561-rv5j1201	714	10	moderate	moderate	JJ
cord-022561-rv5j1201	714	11	to	to	IN
cord-022561-rv5j1201	714	12	severe	severe	JJ
cord-022561-rv5j1201	714	13	,	,	,
cord-022561-rv5j1201	714	14	extravascular	extravascular	JJ
cord-022561-rv5j1201	714	15	,	,	,
cord-022561-rv5j1201	714	16	and	and	CC
cord-022561-rv5j1201	714	17	strongly	strongly	RB
cord-022561-rv5j1201	714	18	regenerative	regenerative	JJ
cord-022561-rv5j1201	714	19	.	.	.
cord-022561-rv5j1201	715	1	With	with	IN
cord-022561-rv5j1201	715	2	chronicity	chronicity	NN
cord-022561-rv5j1201	715	3	,	,	,
cord-022561-rv5j1201	715	4	hemolytic	hemolytic	JJ
cord-022561-rv5j1201	715	5	anemia	anemia	NN
cord-022561-rv5j1201	715	6	causes	cause	VBZ
cord-022561-rv5j1201	715	7	enhanced	enhance	VBN
cord-022561-rv5j1201	715	8	intestinal	intestinal	JJ
cord-022561-rv5j1201	715	9	absorption	absorption	NN
cord-022561-rv5j1201	715	10	of	of	IN
cord-022561-rv5j1201	715	11	iron	iron	NN
cord-022561-rv5j1201	715	12	and	and	CC
cord-022561-rv5j1201	715	13	subsequent	subsequent	JJ
cord-022561-rv5j1201	715	14	hemosiderosis	hemosiderosis	NN
cord-022561-rv5j1201	715	15	,	,	,
cord-022561-rv5j1201	715	16	especially	especially	RB
cord-022561-rv5j1201	715	17	of	of	IN
cord-022561-rv5j1201	715	18	the	the	DT
cord-022561-rv5j1201	715	19	liver	liver	NN
cord-022561-rv5j1201	715	20	and	and	CC
cord-022561-rv5j1201	715	21	bone	bone	NN
cord-022561-rv5j1201	715	22	marrow	marrow	NN
cord-022561-rv5j1201	715	23	.	.	.
cord-022561-rv5j1201	716	1	Dogs	dog	NNS
cord-022561-rv5j1201	716	2	typically	typically	RB
cord-022561-rv5j1201	716	3	die	die	VBP
cord-022561-rv5j1201	716	4	at	at	IN
cord-022561-rv5j1201	716	5	1	1	CD
cord-022561-rv5j1201	716	6	to	to	IN
cord-022561-rv5j1201	716	7	5	5	CD
cord-022561-rv5j1201	716	8	years	year	NNS
cord-022561-rv5j1201	716	9	of	of	IN
cord-022561-rv5j1201	716	10	age	age	NN
cord-022561-rv5j1201	716	11	of	of	IN
cord-022561-rv5j1201	716	12	hemochromatosis	hemochromatosis	NN
cord-022561-rv5j1201	716	13	-	-	HYPH
cord-022561-rv5j1201	716	14	induced	induce	VBN
cord-022561-rv5j1201	716	15	liver	liver	NN
cord-022561-rv5j1201	716	16	and	and	CC
cord-022561-rv5j1201	716	17	bone	bone	NN
cord-022561-rv5j1201	716	18	marrow	marrow	NN
cord-022561-rv5j1201	716	19	failure	failure	NN
cord-022561-rv5j1201	716	20	.	.	.
cord-022561-rv5j1201	717	1	However	however	RB
cord-022561-rv5j1201	717	2	,	,	,
cord-022561-rv5j1201	717	3	cats	cat	NNS
cord-022561-rv5j1201	717	4	with	with	IN
cord-022561-rv5j1201	717	5	PK	PK	NNP
cord-022561-rv5j1201	717	6	deficiency	deficiency	NN
cord-022561-rv5j1201	717	7	typically	typically	RB
cord-022561-rv5j1201	717	8	show	show	VBP
cord-022561-rv5j1201	717	9	no	no	DT
cord-022561-rv5j1201	717	10	clinical	clinical	JJ
cord-022561-rv5j1201	717	11	signs	sign	NNS
cord-022561-rv5j1201	717	12	,	,	,
cord-022561-rv5j1201	717	13	have	have	VBP
cord-022561-rv5j1201	717	14	milder	mild	JJR
cord-022561-rv5j1201	717	15	anemia	anemia	NN
cord-022561-rv5j1201	717	16	,	,	,
cord-022561-rv5j1201	717	17	and	and	CC
cord-022561-rv5j1201	717	18	do	do	VBP
cord-022561-rv5j1201	717	19	not	not	RB
cord-022561-rv5j1201	717	20	develop	develop	VB
cord-022561-rv5j1201	717	21	organ	organ	NN
cord-022561-rv5j1201	717	22	failure	failure	NN
cord-022561-rv5j1201	717	23	.	.	.
cord-022561-rv5j1201	718	1	Grossly	grossly	RB
cord-022561-rv5j1201	718	2	,	,	,
cord-022561-rv5j1201	718	3	affected	affected	JJ
cord-022561-rv5j1201	718	4	animals	animal	NNS
cord-022561-rv5j1201	718	5	have	have	VBP
cord-022561-rv5j1201	718	6	lesions	lesion	NNS
cord-022561-rv5j1201	718	7	attributed	attribute	VBN
cord-022561-rv5j1201	718	8	to	to	IN
cord-022561-rv5j1201	718	9	hemolytic	hemolytic	JJ
cord-022561-rv5j1201	718	10	anemia	anemia	NN
cord-022561-rv5j1201	718	11	,	,	,
cord-022561-rv5j1201	718	12	including	include	VBG
cord-022561-rv5j1201	718	13	splenomegaly	splenomegaly	NN
cord-022561-rv5j1201	718	14	,	,	,
cord-022561-rv5j1201	718	15	pale	pale	JJ
cord-022561-rv5j1201	718	16	mucous	mucous	JJ
cord-022561-rv5j1201	718	17	membranes	membrane	NNS
cord-022561-rv5j1201	718	18	,	,	,
cord-022561-rv5j1201	718	19	and	and	CC
cord-022561-rv5j1201	718	20	rarely	rarely	RB
cord-022561-rv5j1201	718	21	icterus	icterus	NN
cord-022561-rv5j1201	718	22	.	.	.
cord-022561-rv5j1201	719	1	Dogs	dog	NNS
cord-022561-rv5j1201	719	2	with	with	IN
cord-022561-rv5j1201	719	3	end	end	NN
cord-022561-rv5j1201	719	4	-	-	HYPH
cord-022561-rv5j1201	719	5	stage	stage	NN
cord-022561-rv5j1201	719	6	disease	disease	NN
cord-022561-rv5j1201	719	7	have	have	VBP
cord-022561-rv5j1201	719	8	cirrhosis	cirrhosis	NN
cord-022561-rv5j1201	719	9	,	,	,
cord-022561-rv5j1201	719	10	myelofibrosis	myelofibrosis	NNP
cord-022561-rv5j1201	719	11	,	,	,
cord-022561-rv5j1201	719	12	and	and	CC
cord-022561-rv5j1201	719	13	osteosclerosis	osteosclerosis	NN
cord-022561-rv5j1201	719	14	.	.	.
cord-022561-rv5j1201	720	1	Dogs	dog	NNS
cord-022561-rv5j1201	720	2	with	with	IN
cord-022561-rv5j1201	720	3	PK	PK	NNP
cord-022561-rv5j1201	720	4	deficiency	deficiency	NN
cord-022561-rv5j1201	720	5	do	do	VBP
cord-022561-rv5j1201	720	6	not	not	RB
cord-022561-rv5j1201	720	7	necessarily	necessarily	RB
cord-022561-rv5j1201	720	8	have	have	VB
cord-022561-rv5j1201	720	9	the	the	DT
cord-022561-rv5j1201	720	10	same	same	JJ
cord-022561-rv5j1201	720	11	genetic	genetic	JJ
cord-022561-rv5j1201	720	12	defect	defect	NN
cord-022561-rv5j1201	720	13	,	,	,
cord-022561-rv5j1201	720	14	so	so	RB
cord-022561-rv5j1201	720	15	mutation	mutation	NN
cord-022561-rv5j1201	720	16	-	-	HYPH
cord-022561-rv5j1201	720	17	specific	specific	JJ
cord-022561-rv5j1201	720	18	DNA	dna	NN
cord-022561-rv5j1201	720	19	-	-	HYPH
cord-022561-rv5j1201	720	20	based	base	VBN
cord-022561-rv5j1201	720	21	assays	assay	NNS
cord-022561-rv5j1201	720	22	are	be	VBP
cord-022561-rv5j1201	720	23	required	require	VBN
cord-022561-rv5j1201	720	24	.	.	.
cord-022561-rv5j1201	721	1	In	in	IN
cord-022561-rv5j1201	721	2	contrast	contrast	NN
cord-022561-rv5j1201	721	3	,	,	,
cord-022561-rv5j1201	721	4	a	a	DT
cord-022561-rv5j1201	721	5	single	single	JJ
cord-022561-rv5j1201	721	6	DNA	dna	NN
cord-022561-rv5j1201	721	7	-	-	HYPH
cord-022561-rv5j1201	721	8	based	base	VBN
cord-022561-rv5j1201	721	9	test	test	NN
cord-022561-rv5j1201	721	10	is	be	VBZ
cord-022561-rv5j1201	721	11	available	available	JJ
cord-022561-rv5j1201	721	12	to	to	TO
cord-022561-rv5j1201	721	13	detect	detect	VB
cord-022561-rv5j1201	721	14	the	the	DT
cord-022561-rv5j1201	721	15	common	common	JJ
cord-022561-rv5j1201	721	16	mutation	mutation	NN
cord-022561-rv5j1201	721	17	affecting	affect	VBG
cord-022561-rv5j1201	721	18	Abyssinian	Abyssinian	NNP
cord-022561-rv5j1201	721	19	,	,	,
cord-022561-rv5j1201	721	20	Somali	somali	JJ
cord-022561-rv5j1201	721	21	,	,	,
cord-022561-rv5j1201	721	22	and	and	CC
cord-022561-rv5j1201	721	23	domestic	domestic	JJ
cord-022561-rv5j1201	721	24	shorthair	shorthair	JJ
cord-022561-rv5j1201	721	25	cats	cat	NNS
cord-022561-rv5j1201	721	26	.	.	.
cord-022561-rv5j1201	722	1	Cytochrome	cytochrome	NN
cord-022561-rv5j1201	722	2	-	-	HYPH
cord-022561-rv5j1201	722	3	b	b	NN
cord-022561-rv5j1201	722	4	5	5	CD
cord-022561-rv5j1201	722	5	Reductase	Reductase	NNP
cord-022561-rv5j1201	722	6	Deficiency	deficiency	NN
cord-022561-rv5j1201	722	7	.	.	.
cord-022561-rv5j1201	723	1	Deficiency	deficiency	NN
cord-022561-rv5j1201	723	2	of	of	IN
cord-022561-rv5j1201	723	3	cytochrome	cytochrome	NN
cord-022561-rv5j1201	723	4	-	-	HYPH
cord-022561-rv5j1201	723	5	b	b	NN
cord-022561-rv5j1201	723	6	5	5	CD
cord-022561-rv5j1201	723	7	reductase	reductase	NN
cord-022561-rv5j1201	723	8	(	(	-LRB-
cord-022561-rv5j1201	723	9	Cb5R	Cb5R	NNP
cord-022561-rv5j1201	723	10	,	,	,
cord-022561-rv5j1201	723	11	also	also	RB
cord-022561-rv5j1201	723	12	known	know	VBN
cord-022561-rv5j1201	723	13	as	as	IN
cord-022561-rv5j1201	723	14	methemoglobin	methemoglobin	NNP
cord-022561-rv5j1201	723	15	reductase	reductase	NNP
cord-022561-rv5j1201	723	16	)	)	-RRB-
cord-022561-rv5j1201	723	17	,	,	,
cord-022561-rv5j1201	723	18	the	the	DT
cord-022561-rv5j1201	723	19	enzyme	enzyme	NN
cord-022561-rv5j1201	723	20	that	that	WDT
cord-022561-rv5j1201	723	21	catalyzes	catalyze	VBZ
cord-022561-rv5j1201	723	22	the	the	DT
cord-022561-rv5j1201	723	23	reduction	reduction	NN
cord-022561-rv5j1201	723	24	of	of	IN
cord-022561-rv5j1201	723	25	methemoglobin	methemoglobin	NNP
cord-022561-rv5j1201	723	26	(	(	-LRB-
cord-022561-rv5j1201	723	27	Fe	Fe	NNP
cord-022561-rv5j1201	723	28	3	3	CD
cord-022561-rv5j1201	723	29	+	+	SYM
cord-022561-rv5j1201	723	30	)	)	-RRB-
cord-022561-rv5j1201	723	31	to	to	IN
cord-022561-rv5j1201	723	32	hemoglobin	hemoglobin	NN
cord-022561-rv5j1201	723	33	(	(	-LRB-
cord-022561-rv5j1201	723	34	Fe	Fe	NNP
cord-022561-rv5j1201	723	35	2	2	CD
cord-022561-rv5j1201	723	36	+	+	SYM
cord-022561-rv5j1201	723	37	)	)	-RRB-
cord-022561-rv5j1201	723	38	,	,	,
cord-022561-rv5j1201	723	39	has	have	VBZ
cord-022561-rv5j1201	723	40	been	be	VBN
cord-022561-rv5j1201	723	41	recognized	recognize	VBN
cord-022561-rv5j1201	723	42	in	in	IN
cord-022561-rv5j1201	723	43	many	many	JJ
cord-022561-rv5j1201	723	44	dog	dog	NN
cord-022561-rv5j1201	723	45	breeds	breed	NNS
cord-022561-rv5j1201	723	46	and	and	CC
cord-022561-rv5j1201	723	47	in	in	IN
cord-022561-rv5j1201	723	48	domestic	domestic	JJ
cord-022561-rv5j1201	723	49	shorthair	shorthair	JJ
cord-022561-rv5j1201	723	50	cats	cat	NNS
cord-022561-rv5j1201	723	51	.	.	.
cord-022561-rv5j1201	724	1	It	-PRON-	PRP
cord-022561-rv5j1201	724	2	is	be	VBZ
cord-022561-rv5j1201	724	3	probably	probably	RB
cord-022561-rv5j1201	724	4	an	an	DT
cord-022561-rv5j1201	724	5	autosomal	autosomal	JJ
cord-022561-rv5j1201	724	6	recessive	recessive	JJ
cord-022561-rv5j1201	724	7	trait	trait	NN
cord-022561-rv5j1201	724	8	.	.	.
cord-022561-rv5j1201	725	1	Affected	affected	JJ
cord-022561-rv5j1201	725	2	animals	animal	NNS
cord-022561-rv5j1201	725	3	may	may	MD
cord-022561-rv5j1201	725	4	have	have	VB
cord-022561-rv5j1201	725	5	cyanotic	cyanotic	JJ
cord-022561-rv5j1201	725	6	mucous	mucous	JJ
cord-022561-rv5j1201	725	7	membranes	membrane	NNS
cord-022561-rv5j1201	725	8	or	or	CC
cord-022561-rv5j1201	725	9	exercise	exercise	VB
cord-022561-rv5j1201	725	10	intolerance	intolerance	NN
cord-022561-rv5j1201	725	11	but	but	CC
cord-022561-rv5j1201	725	12	usually	usually	RB
cord-022561-rv5j1201	725	13	lack	lack	VBP
cord-022561-rv5j1201	725	14	anemia	anemia	NN
cord-022561-rv5j1201	725	15	and	and	CC
cord-022561-rv5j1201	725	16	clinical	clinical	JJ
cord-022561-rv5j1201	725	17	signs	sign	NNS
cord-022561-rv5j1201	725	18	of	of	IN
cord-022561-rv5j1201	725	19	disease	disease	NN
cord-022561-rv5j1201	725	20	.	.	.
cord-022561-rv5j1201	726	1	Life	life	NN
cord-022561-rv5j1201	726	2	expectancies	expectancy	NNS
cord-022561-rv5j1201	726	3	are	be	VBP
cord-022561-rv5j1201	726	4	normal	normal	JJ
cord-022561-rv5j1201	726	5	.	.	.
cord-022561-rv5j1201	727	1	Glucose-6-Phosphate	Glucose-6-Phosphate	NNP
cord-022561-rv5j1201	727	2	Dehydrogenase	Dehydrogenase	NNP
cord-022561-rv5j1201	727	3	Deficiency	deficiency	NN
cord-022561-rv5j1201	727	4	.	.	.
cord-022561-rv5j1201	728	1	Deficiency	deficiency	NN
cord-022561-rv5j1201	728	2	of	of	IN
cord-022561-rv5j1201	728	3	glucose-6-phosphate	glucose-6-phosphate	JJ
cord-022561-rv5j1201	728	4	dehydrogenase	dehydrogenase	NN
cord-022561-rv5j1201	728	5	(	(	-LRB-
cord-022561-rv5j1201	728	6	G6PD	G6PD	NNP
cord-022561-rv5j1201	728	7	)	)	-RRB-
cord-022561-rv5j1201	728	8	,	,	,
cord-022561-rv5j1201	728	9	the	the	DT
cord-022561-rv5j1201	728	10	ratecontrolling	ratecontrolling	NN
cord-022561-rv5j1201	728	11	enzyme	enzyme	NN
cord-022561-rv5j1201	728	12	of	of	IN
cord-022561-rv5j1201	728	13	the	the	DT
cord-022561-rv5j1201	728	14	pentose	pentose	NN
cord-022561-rv5j1201	728	15	phosphate	phosphate	NN
cord-022561-rv5j1201	728	16	pathway	pathway	NN
cord-022561-rv5j1201	728	17	(	(	-LRB-
cord-022561-rv5j1201	728	18	PPP	PPP	NNP
cord-022561-rv5j1201	728	19	)	)	-RRB-
cord-022561-rv5j1201	728	20	,	,	,
cord-022561-rv5j1201	728	21	has	have	VBZ
cord-022561-rv5j1201	728	22	been	be	VBN
cord-022561-rv5j1201	728	23	reported	report	VBN
cord-022561-rv5j1201	728	24	in	in	IN
cord-022561-rv5j1201	728	25	an	an	DT
cord-022561-rv5j1201	728	26	American	american	JJ
cord-022561-rv5j1201	728	27	saddlebred	saddlebred	JJ
cord-022561-rv5j1201	728	28	colt	colt	NN
cord-022561-rv5j1201	728	29	,	,	,
cord-022561-rv5j1201	728	30	its	-PRON-	PRP$
cord-022561-rv5j1201	728	31	dam	dam	NN
cord-022561-rv5j1201	728	32	,	,	,
cord-022561-rv5j1201	728	33	and	and	CC
cord-022561-rv5j1201	728	34	one	one	CD
cord-022561-rv5j1201	728	35	male	male	JJ
cord-022561-rv5j1201	728	36	dog	dog	NN
cord-022561-rv5j1201	728	37	.	.	.
cord-022561-rv5j1201	729	1	The	the	DT
cord-022561-rv5j1201	729	2	PPP	PPP	NNP
cord-022561-rv5j1201	729	3	is	be	VBZ
cord-022561-rv5j1201	729	4	an	an	DT
cord-022561-rv5j1201	729	5	antioxidative	antioxidative	JJ
cord-022561-rv5j1201	729	6	pathway	pathway	NN
cord-022561-rv5j1201	729	7	that	that	WDT
cord-022561-rv5j1201	729	8	generates	generate	VBZ
cord-022561-rv5j1201	729	9	NADPH	NADPH	NNP
cord-022561-rv5j1201	729	10	,	,	,
cord-022561-rv5j1201	729	11	which	which	WDT
cord-022561-rv5j1201	729	12	maintains	maintain	VBZ
cord-022561-rv5j1201	729	13	glutathione	glutathione	NN
cord-022561-rv5j1201	729	14	in	in	IN
cord-022561-rv5j1201	729	15	its	-PRON-	PRP$
cord-022561-rv5j1201	729	16	reduced	reduce	VBN
cord-022561-rv5j1201	729	17	form	form	NN
cord-022561-rv5j1201	729	18	(	(	-LRB-
cord-022561-rv5j1201	729	19	GSH	GSH	NNP
cord-022561-rv5j1201	729	20	)	)	-RRB-
cord-022561-rv5j1201	729	21	.	.	.
cord-022561-rv5j1201	730	1	Therefore	therefore	RB
cord-022561-rv5j1201	730	2	in	in	IN
cord-022561-rv5j1201	730	3	animals	animal	NNS
cord-022561-rv5j1201	730	4	with	with	IN
cord-022561-rv5j1201	730	5	G6PD	G6PD	NNP
cord-022561-rv5j1201	730	6	deficiency	deficiency	NN
cord-022561-rv5j1201	730	7	,	,	,
cord-022561-rv5j1201	730	8	oxidants	oxidant	NNS
cord-022561-rv5j1201	730	9	are	be	VBP
cord-022561-rv5j1201	730	10	not	not	RB
cord-022561-rv5j1201	730	11	scavenged	scavenge	VBN
cord-022561-rv5j1201	730	12	,	,	,
cord-022561-rv5j1201	730	13	and	and	CC
cord-022561-rv5j1201	730	14	erythrocyte	erythrocyte	NN
cord-022561-rv5j1201	730	15	oxidative	oxidative	JJ
cord-022561-rv5j1201	730	16	injury	injury	NN
cord-022561-rv5j1201	730	17	occurs	occur	VBZ
cord-022561-rv5j1201	730	18	.	.	.
cord-022561-rv5j1201	731	1	The	the	DT
cord-022561-rv5j1201	731	2	colt	colt	NN
cord-022561-rv5j1201	731	3	with	with	IN
cord-022561-rv5j1201	731	4	G6PD	G6PD	NNP
cord-022561-rv5j1201	731	5	deficiency	deficiency	NN
cord-022561-rv5j1201	731	6	had	have	VBD
cord-022561-rv5j1201	731	7	severe	severe	JJ
cord-022561-rv5j1201	731	8	oxidative	oxidative	JJ
cord-022561-rv5j1201	731	9	hemolytic	hemolytic	JJ
cord-022561-rv5j1201	731	10	anemia	anemia	NN
cord-022561-rv5j1201	731	11	with	with	IN
cord-022561-rv5j1201	731	12	eccentrocytes	eccentrocyte	NNS
cord-022561-rv5j1201	731	13	on	on	IN
cord-022561-rv5j1201	731	14	blood	blood	NN
cord-022561-rv5j1201	731	15	smear	smear	NN
cord-022561-rv5j1201	731	16	evaluation	evaluation	NN
cord-022561-rv5j1201	731	17	.	.	.
cord-022561-rv5j1201	732	1	However	however	RB
cord-022561-rv5j1201	732	2	,	,	,
cord-022561-rv5j1201	732	3	the	the	DT
cord-022561-rv5j1201	732	4	colt	colt	NN
cord-022561-rv5j1201	732	5	's	's	POS
cord-022561-rv5j1201	732	6	dam	dam	NN
cord-022561-rv5j1201	732	7	only	only	RB
cord-022561-rv5j1201	732	8	had	have	VBD
cord-022561-rv5j1201	732	9	eccentrocytes	eccentrocyte	NNS
cord-022561-rv5j1201	732	10	,	,	,
cord-022561-rv5j1201	732	11	and	and	CC
cord-022561-rv5j1201	732	12	showed	show	VBD
cord-022561-rv5j1201	732	13	no	no	DT
cord-022561-rv5j1201	732	14	hematologic	hematologic	JJ
cord-022561-rv5j1201	732	15	signs	sign	NNS
cord-022561-rv5j1201	732	16	of	of	IN
cord-022561-rv5j1201	732	17	disease	disease	NN
cord-022561-rv5j1201	732	18	.	.	.
cord-022561-rv5j1201	733	1	Leukocyte	Leukocyte	NNP
cord-022561-rv5j1201	733	2	Adhesion	Adhesion	NNP
cord-022561-rv5j1201	733	3	Deficiency	Deficiency	NNP
cord-022561-rv5j1201	733	4	.	.	.
cord-022561-rv5j1201	734	1	Leukocyte	Leukocyte	NNP
cord-022561-rv5j1201	734	2	adhesion	adhesion	NN
cord-022561-rv5j1201	734	3	deficiency	deficiency	NN
cord-022561-rv5j1201	734	4	(	(	-LRB-
cord-022561-rv5j1201	734	5	LAD	lad	NN
cord-022561-rv5j1201	734	6	)	)	-RRB-
cord-022561-rv5j1201	734	7	is	be	VBZ
cord-022561-rv5j1201	734	8	a	a	DT
cord-022561-rv5j1201	734	9	fatal	fatal	JJ
cord-022561-rv5j1201	734	10	autosomal	autosomal	JJ
cord-022561-rv5j1201	734	11	recessive	recessive	JJ
cord-022561-rv5j1201	734	12	defect	defect	NN
cord-022561-rv5j1201	734	13	of	of	IN
cord-022561-rv5j1201	734	14	leukocyte	leukocyte	NN
cord-022561-rv5j1201	734	15	integrins	integrin	NNS
cord-022561-rv5j1201	734	16	,	,	,
cord-022561-rv5j1201	734	17	in	in	IN
cord-022561-rv5j1201	734	18	particular	particular	JJ
cord-022561-rv5j1201	734	19	the	the	DT
cord-022561-rv5j1201	734	20	β	β	NN
cord-022561-rv5j1201	734	21	2	2	CD
cord-022561-rv5j1201	734	22	chain	chain	NN
cord-022561-rv5j1201	734	23	(	(	-LRB-
cord-022561-rv5j1201	734	24	also	also	RB
cord-022561-rv5j1201	734	25	known	know	VBN
cord-022561-rv5j1201	734	26	as	as	IN
cord-022561-rv5j1201	734	27	cluster	cluster	NN
cord-022561-rv5j1201	734	28	of	of	IN
cord-022561-rv5j1201	734	29	differentiation	differentiation	NN
cord-022561-rv5j1201	734	30	[	[	-LRB-
cord-022561-rv5j1201	734	31	CD	CD	NNP
cord-022561-rv5j1201	734	32	]	]	-RRB-
cord-022561-rv5j1201	734	33	18	18	CD
cord-022561-rv5j1201	735	1	[	[	-LRB-
cord-022561-rv5j1201	735	2	CD18	CD18	NNP
cord-022561-rv5j1201	735	3	]	]	-RRB-
cord-022561-rv5j1201	735	4	)	)	-RRB-
cord-022561-rv5j1201	735	5	.	.	.
cord-022561-rv5j1201	736	1	Disease	Disease	NNP
cord-022561-rv5j1201	736	2	has	have	VBZ
cord-022561-rv5j1201	736	3	been	be	VBN
cord-022561-rv5j1201	736	4	recognized	recognize	VBN
cord-022561-rv5j1201	736	5	in	in	IN
cord-022561-rv5j1201	736	6	Holstein	Holstein	NNP
cord-022561-rv5j1201	736	7	cattle	cattle	NNS
cord-022561-rv5j1201	736	8	(	(	-LRB-
cord-022561-rv5j1201	736	9	known	know	VBN
cord-022561-rv5j1201	736	10	as	as	IN
cord-022561-rv5j1201	736	11	bovine	bovine	JJ
cord-022561-rv5j1201	736	12	leukocyte	leukocyte	NN
cord-022561-rv5j1201	736	13	adhesion	adhesion	NN
cord-022561-rv5j1201	736	14	deficiency	deficiency	NN
cord-022561-rv5j1201	736	15	[	[	-LRB-
cord-022561-rv5j1201	736	16	BLAD	BLAD	NNP
cord-022561-rv5j1201	736	17	]	]	-RRB-
cord-022561-rv5j1201	736	18	)	)	-RRB-
cord-022561-rv5j1201	736	19	and	and	CC
cord-022561-rv5j1201	736	20	Irish	irish	JJ
cord-022561-rv5j1201	736	21	setter	setter	NN
cord-022561-rv5j1201	736	22	dogs	dog	NNS
cord-022561-rv5j1201	736	23	(	(	-LRB-
cord-022561-rv5j1201	736	24	known	know	VBN
cord-022561-rv5j1201	736	25	as	as	IN
cord-022561-rv5j1201	736	26	canine	canine	JJ
cord-022561-rv5j1201	736	27	leukocyte	leukocyte	NN
cord-022561-rv5j1201	736	28	adhesion	adhesion	NN
cord-022561-rv5j1201	736	29	deficiency	deficiency	NN
cord-022561-rv5j1201	736	30	[	[	-LRB-
cord-022561-rv5j1201	736	31	CLAD	CLAD	NNP
cord-022561-rv5j1201	736	32	]	]	-RRB-
cord-022561-rv5j1201	736	33	)	)	-RRB-
cord-022561-rv5j1201	736	34	(	(	-LRB-
cord-022561-rv5j1201	736	35	see	see	VB
cord-022561-rv5j1201	736	36	Chapter	chapter	NN
cord-022561-rv5j1201	736	37	3	3	CD
cord-022561-rv5j1201	736	38	)	)	-RRB-
cord-022561-rv5j1201	736	39	.	.	.
cord-022561-rv5j1201	737	1	Without	without	IN
cord-022561-rv5j1201	737	2	normal	normal	JJ
cord-022561-rv5j1201	737	3	expression	expression	NN
cord-022561-rv5j1201	737	4	of	of	IN
cord-022561-rv5j1201	737	5	this	this	DT
cord-022561-rv5j1201	737	6	adhesion	adhesion	NN
cord-022561-rv5j1201	737	7	molecule	molecule	NN
cord-022561-rv5j1201	737	8	,	,	,
cord-022561-rv5j1201	737	9	leukocytes	leukocyte	NNS
cord-022561-rv5j1201	737	10	have	have	VBP
cord-022561-rv5j1201	737	11	severely	severely	RB
cord-022561-rv5j1201	737	12	impaired	impair	VBN
cord-022561-rv5j1201	737	13	abilities	ability	NNS
cord-022561-rv5j1201	737	14	to	to	TO
cord-022561-rv5j1201	737	15	migrate	migrate	VB
cord-022561-rv5j1201	737	16	from	from	IN
cord-022561-rv5j1201	737	17	the	the	DT
cord-022561-rv5j1201	737	18	blood	blood	NN
cord-022561-rv5j1201	737	19	into	into	IN
cord-022561-rv5j1201	737	20	tissues	tissue	NNS
cord-022561-rv5j1201	737	21	.	.	.
cord-022561-rv5j1201	738	1	As	as	IN
cord-022561-rv5j1201	738	2	a	a	DT
cord-022561-rv5j1201	738	3	result	result	NN
cord-022561-rv5j1201	738	4	,	,	,
cord-022561-rv5j1201	738	5	animals	animal	NNS
cord-022561-rv5j1201	738	6	with	with	IN
cord-022561-rv5j1201	738	7	leukocyte	leukocyte	NN
cord-022561-rv5j1201	738	8	adhesion	adhesion	NN
cord-022561-rv5j1201	738	9	deficiency	deficiency	NN
cord-022561-rv5j1201	738	10	have	have	VBP
cord-022561-rv5j1201	738	11	marked	mark	VBN
cord-022561-rv5j1201	738	12	neutrophilia	neutrophilia	NNP
cord-022561-rv5j1201	738	13	with	with	IN
cord-022561-rv5j1201	738	14	nonsuppurative	nonsuppurative	NNP
cord-022561-rv5j1201	738	15	multisystemic	multisystemic	NNP
cord-022561-rv5j1201	738	16	infections	infection	NNS
cord-022561-rv5j1201	738	17	.	.	.
cord-022561-rv5j1201	739	1	Blood	blood	NN
cord-022561-rv5j1201	739	2	neutrophils	neutrophil	NNS
cord-022561-rv5j1201	739	3	often	often	RB
cord-022561-rv5j1201	739	4	have	have	VBP
cord-022561-rv5j1201	739	5	nuclei	nucleus	NNS
cord-022561-rv5j1201	739	6	with	with	IN
cord-022561-rv5j1201	739	7	greater	great	JJR
cord-022561-rv5j1201	739	8	than	than	IN
cord-022561-rv5j1201	739	9	five	five	CD
cord-022561-rv5j1201	739	10	nuclear	nuclear	JJ
cord-022561-rv5j1201	739	11	segments	segment	NNS
cord-022561-rv5j1201	739	12	,	,	,
cord-022561-rv5j1201	739	13	termed	term	VBD
cord-022561-rv5j1201	739	14	not	not	RB
cord-022561-rv5j1201	739	15	comprehensive	comprehensive	JJ
cord-022561-rv5j1201	739	16	but	but	CC
cord-022561-rv5j1201	739	17	instead	instead	RB
cord-022561-rv5j1201	739	18	focus	focus	VB
cord-022561-rv5j1201	739	19	on	on	IN
cord-022561-rv5j1201	739	20	the	the	DT
cord-022561-rv5j1201	739	21	more	more	RBR
cord-022561-rv5j1201	739	22	common	common	JJ
cord-022561-rv5j1201	739	23	,	,	,
cord-022561-rv5j1201	739	24	wellcharacterized	wellcharacterized	JJ
cord-022561-rv5j1201	739	25	,	,	,
cord-022561-rv5j1201	739	26	or	or	CC
cord-022561-rv5j1201	739	27	recently	recently	RB
cord-022561-rv5j1201	739	28	reported	report	VBN
cord-022561-rv5j1201	739	29	conditions	condition	NNS
cord-022561-rv5j1201	739	30	.	.	.
cord-022561-rv5j1201	740	1	Erythropoietic	Erythropoietic	NNP
cord-022561-rv5j1201	740	2	Porphyrias	Porphyrias	NNP
cord-022561-rv5j1201	740	3	.	.	.
cord-022561-rv5j1201	741	1	Porphyrias	Porphyrias	NNP
cord-022561-rv5j1201	741	2	are	be	VBP
cord-022561-rv5j1201	741	3	a	a	DT
cord-022561-rv5j1201	741	4	group	group	NN
cord-022561-rv5j1201	741	5	of	of	IN
cord-022561-rv5j1201	741	6	hereditary	hereditary	JJ
cord-022561-rv5j1201	741	7	disorders	disorder	NNS
cord-022561-rv5j1201	741	8	in	in	IN
cord-022561-rv5j1201	741	9	which	which	WDT
cord-022561-rv5j1201	741	10	porphyrins	porphyrin	NNS
cord-022561-rv5j1201	741	11	accumulate	accumulate	VBP
cord-022561-rv5j1201	741	12	in	in	IN
cord-022561-rv5j1201	741	13	the	the	DT
cord-022561-rv5j1201	741	14	body	body	NN
cord-022561-rv5j1201	741	15	because	because	IN
cord-022561-rv5j1201	741	16	of	of	IN
cord-022561-rv5j1201	741	17	defective	defective	JJ
cord-022561-rv5j1201	741	18	heme	heme	NN
cord-022561-rv5j1201	741	19	synthesis	synthesis	NN
cord-022561-rv5j1201	741	20	.	.	.
cord-022561-rv5j1201	742	1	Inherited	inherit	VBN
cord-022561-rv5j1201	742	2	enzyme	enzyme	NN
cord-022561-rv5j1201	742	3	defects	defect	NNS
cord-022561-rv5j1201	742	4	in	in	IN
cord-022561-rv5j1201	742	5	hemoglobin	hemoglobin	NN
cord-022561-rv5j1201	742	6	synthesis	synthesis	NN
cord-022561-rv5j1201	742	7	have	have	VBP
cord-022561-rv5j1201	742	8	been	be	VBN
cord-022561-rv5j1201	742	9	identified	identify	VBN
cord-022561-rv5j1201	742	10	in	in	IN
cord-022561-rv5j1201	742	11	Holstein	Holstein	NNP
cord-022561-rv5j1201	742	12	cattle	cattle	NNS
cord-022561-rv5j1201	742	13	,	,	,
cord-022561-rv5j1201	742	14	Siamese	siamese	JJ
cord-022561-rv5j1201	742	15	cats	cat	NNS
cord-022561-rv5j1201	742	16	,	,	,
cord-022561-rv5j1201	742	17	and	and	CC
cord-022561-rv5j1201	742	18	other	other	JJ
cord-022561-rv5j1201	742	19	cattle	cattle	NNS
cord-022561-rv5j1201	742	20	and	and	CC
cord-022561-rv5j1201	742	21	cat	cat	NN
cord-022561-rv5j1201	742	22	breeds	breed	NNS
cord-022561-rv5j1201	742	23	,	,	,
cord-022561-rv5j1201	742	24	resulting	result	VBG
cord-022561-rv5j1201	742	25	in	in	IN
cord-022561-rv5j1201	742	26	bovine	bovine	JJ
cord-022561-rv5j1201	742	27	congenital	congenital	JJ
cord-022561-rv5j1201	742	28	erythropoietic	erythropoietic	NN
cord-022561-rv5j1201	742	29	porphyria	porphyria	NN
cord-022561-rv5j1201	742	30	and	and	CC
cord-022561-rv5j1201	742	31	feline	feline	JJ
cord-022561-rv5j1201	742	32	erythropoietic	erythropoietic	NN
cord-022561-rv5j1201	742	33	porphyria	porphyria	NN
cord-022561-rv5j1201	742	34	,	,	,
cord-022561-rv5j1201	742	35	respectively	respectively	RB
cord-022561-rv5j1201	742	36	.	.	.
cord-022561-rv5j1201	743	1	Accumulation	accumulation	NN
cord-022561-rv5j1201	743	2	of	of	IN
cord-022561-rv5j1201	743	3	toxic	toxic	JJ
cord-022561-rv5j1201	743	4	porphyrins	porphyrin	NNS
cord-022561-rv5j1201	743	5	in	in	IN
cord-022561-rv5j1201	743	6	erythrocytes	erythrocyte	NNS
cord-022561-rv5j1201	743	7	causes	cause	VBZ
cord-022561-rv5j1201	743	8	hemolytic	hemolytic	JJ
cord-022561-rv5j1201	743	9	anemia	anemia	NN
cord-022561-rv5j1201	743	10	,	,	,
cord-022561-rv5j1201	743	11	whereas	whereas	IN
cord-022561-rv5j1201	743	12	accumulation	accumulation	NN
cord-022561-rv5j1201	743	13	of	of	IN
cord-022561-rv5j1201	743	14	porphyrins	porphyrin	NNS
cord-022561-rv5j1201	743	15	in	in	IN
cord-022561-rv5j1201	743	16	tissues	tissue	NNS
cord-022561-rv5j1201	743	17	and	and	CC
cord-022561-rv5j1201	743	18	fluids	fluid	NNS
cord-022561-rv5j1201	743	19	produces	produce	VBZ
cord-022561-rv5j1201	743	20	discoloration	discoloration	NN
cord-022561-rv5j1201	743	21	,	,	,
cord-022561-rv5j1201	743	22	including	include	VBG
cord-022561-rv5j1201	743	23	red	red	JJ
cord-022561-rv5j1201	743	24	-	-	HYPH
cord-022561-rv5j1201	743	25	brown	brown	JJ
cord-022561-rv5j1201	743	26	teeth	tooth	NNS
cord-022561-rv5j1201	743	27	,	,	,
cord-022561-rv5j1201	743	28	bones	bone	NNS
cord-022561-rv5j1201	743	29	,	,	,
cord-022561-rv5j1201	743	30	and	and	CC
cord-022561-rv5j1201	743	31	urine	urine	NN
cord-022561-rv5j1201	743	32	(	(	-LRB-
cord-022561-rv5j1201	743	33	see	see	VB
cord-022561-rv5j1201	743	34	Fig	Fig	NNP
cord-022561-rv5j1201	743	35	.	.	.
cord-022561-rv5j1201	743	36	1	1	CD
cord-022561-rv5j1201	743	37	-59	-59	CD
cord-022561-rv5j1201	743	38	)	)	-RRB-
cord-022561-rv5j1201	743	39	.	.	.
cord-022561-rv5j1201	744	1	Because	because	IN
cord-022561-rv5j1201	744	2	of	of	IN
cord-022561-rv5j1201	744	3	the	the	DT
cord-022561-rv5j1201	744	4	circulation	circulation	NN
cord-022561-rv5j1201	744	5	of	of	IN
cord-022561-rv5j1201	744	6	the	the	DT
cord-022561-rv5j1201	744	7	photodynamic	photodynamic	NN
cord-022561-rv5j1201	744	8	porphyrins	porphyrin	NNS
cord-022561-rv5j1201	744	9	in	in	IN
cord-022561-rv5j1201	744	10	blood	blood	NN
cord-022561-rv5j1201	744	11	,	,	,
cord-022561-rv5j1201	744	12	these	these	DT
cord-022561-rv5j1201	744	13	animals	animal	NNS
cord-022561-rv5j1201	744	14	have	have	VBP
cord-022561-rv5j1201	744	15	lesions	lesion	NNS
cord-022561-rv5j1201	744	16	of	of	IN
cord-022561-rv5j1201	744	17	photosensitization	photosensitization	NN
cord-022561-rv5j1201	744	18	of	of	IN
cord-022561-rv5j1201	744	19	the	the	DT
cord-022561-rv5j1201	744	20	nonpigmented	nonpigmented	JJ
cord-022561-rv5j1201	744	21	skin	skin	NN
cord-022561-rv5j1201	744	22	.	.	.
cord-022561-rv5j1201	745	1	All	all	DT
cord-022561-rv5j1201	745	2	affected	affect	VBN
cord-022561-rv5j1201	745	3	tissues	tissue	NNS
cord-022561-rv5j1201	745	4	,	,	,
cord-022561-rv5j1201	745	5	including	include	VBG
cord-022561-rv5j1201	745	6	erythrocytes	erythrocyte	NNS
cord-022561-rv5j1201	745	7	,	,	,
cord-022561-rv5j1201	745	8	exhibit	exhibit	VB
cord-022561-rv5j1201	745	9	fluorescence	fluorescence	NN
cord-022561-rv5j1201	745	10	with	with	IN
cord-022561-rv5j1201	745	11	ultraviolet	ultraviolet	JJ
cord-022561-rv5j1201	745	12	light	light	NN
cord-022561-rv5j1201	745	13	.	.	.
cord-022561-rv5j1201	746	1	Histologically	histologically	RB
cord-022561-rv5j1201	746	2	,	,	,
cord-022561-rv5j1201	746	3	animals	animal	NNS
cord-022561-rv5j1201	746	4	may	may	MD
cord-022561-rv5j1201	746	5	exhibit	exhibit	VB
cord-022561-rv5j1201	746	6	perivascular	perivascular	JJ
cord-022561-rv5j1201	746	7	dermatitis	dermatitis	NN
cord-022561-rv5j1201	746	8	,	,	,
cord-022561-rv5j1201	746	9	as	as	RB
cord-022561-rv5j1201	746	10	well	well	RB
cord-022561-rv5j1201	746	11	as	as	IN
cord-022561-rv5j1201	746	12	multisystemic	multisystemic	NNP
cord-022561-rv5j1201	746	13	porphyrin	porphyrin	NN
cord-022561-rv5j1201	746	14	deposition	deposition	NN
cord-022561-rv5j1201	746	15	,	,	,
cord-022561-rv5j1201	746	16	hemosiderosis	hemosiderosis	NNP
cord-022561-rv5j1201	746	17	,	,	,
cord-022561-rv5j1201	746	18	EMH	EMH	NNP
cord-022561-rv5j1201	746	19	,	,	,
cord-022561-rv5j1201	746	20	and	and	CC
cord-022561-rv5j1201	746	21	marrow	marrow	NN
cord-022561-rv5j1201	746	22	erythroid	erythroid	NN
cord-022561-rv5j1201	746	23	hyperplasia	hyperplasia	NN
cord-022561-rv5j1201	746	24	.	.	.
cord-022561-rv5j1201	747	1	Cats	cat	NNS
cord-022561-rv5j1201	747	2	may	may	MD
cord-022561-rv5j1201	747	3	show	show	VB
cord-022561-rv5j1201	747	4	evidence	evidence	NN
cord-022561-rv5j1201	747	5	of	of	IN
cord-022561-rv5j1201	747	6	renal	renal	JJ
cord-022561-rv5j1201	747	7	disease	disease	NN
cord-022561-rv5j1201	747	8	,	,	.
cord-022561-rv5j1201	748	1	A	a	DT
cord-022561-rv5j1201	748	2	B	b	NN
cord-022561-rv5j1201	748	3	syndrome	syndrome	NN
cord-022561-rv5j1201	748	4	exhibit	exhibit	NN
cord-022561-rv5j1201	748	5	oculocutaneous	oculocutaneous	JJ
cord-022561-rv5j1201	748	6	albinism	albinism	NN
cord-022561-rv5j1201	748	7	(	(	-LRB-
cord-022561-rv5j1201	748	8	due	due	JJ
cord-022561-rv5j1201	748	9	to	to	IN
cord-022561-rv5j1201	748	10	altered	alter	VBN
cord-022561-rv5j1201	748	11	distribution	distribution	NN
cord-022561-rv5j1201	748	12	of	of	IN
cord-022561-rv5j1201	748	13	melanin	melanin	NN
cord-022561-rv5j1201	748	14	granules	granule	NNS
cord-022561-rv5j1201	748	15	)	)	-RRB-
cord-022561-rv5j1201	748	16	and	and	CC
cord-022561-rv5j1201	748	17	are	be	VBP
cord-022561-rv5j1201	748	18	prone	prone	JJ
cord-022561-rv5j1201	748	19	to	to	IN
cord-022561-rv5j1201	748	20	infection	infection	NN
cord-022561-rv5j1201	748	21	and	and	CC
cord-022561-rv5j1201	748	22	bleeding	bleeding	NN
cord-022561-rv5j1201	748	23	.	.	.
cord-022561-rv5j1201	749	1	Blood	blood	NN
cord-022561-rv5j1201	749	2	smear	smear	NN
cord-022561-rv5j1201	749	3	evaluation	evaluation	NN
cord-022561-rv5j1201	749	4	reveals	reveal	VBZ
cord-022561-rv5j1201	749	5	granulocytes	granulocyte	NNS
cord-022561-rv5j1201	749	6	with	with	IN
cord-022561-rv5j1201	749	7	large	large	JJ
cord-022561-rv5j1201	749	8	cytoplasmic	cytoplasmic	JJ
cord-022561-rv5j1201	749	9	granules	granule	NNS
cord-022561-rv5j1201	749	10	.	.	.
cord-022561-rv5j1201	750	1	Glanzmann	Glanzmann	NNP
cord-022561-rv5j1201	750	2	Thrombasthenia	Thrombasthenia	NNP
cord-022561-rv5j1201	750	3	.	.	.
cord-022561-rv5j1201	751	1	Glanzmann	Glanzmann	NNP
cord-022561-rv5j1201	751	2	thrombasthenia	thrombasthenia	NNP
cord-022561-rv5j1201	751	3	(	(	-LRB-
cord-022561-rv5j1201	751	4	GT	GT	NNP
cord-022561-rv5j1201	751	5	)	)	-RRB-
cord-022561-rv5j1201	751	6	is	be	VBZ
cord-022561-rv5j1201	751	7	an	an	DT
cord-022561-rv5j1201	751	8	inherited	inherit	VBN
cord-022561-rv5j1201	751	9	platelet	platelet	NN
cord-022561-rv5j1201	751	10	function	function	NN
cord-022561-rv5j1201	751	11	defect	defect	NN
cord-022561-rv5j1201	751	12	caused	cause	VBN
cord-022561-rv5j1201	751	13	by	by	IN
cord-022561-rv5j1201	751	14	a	a	DT
cord-022561-rv5j1201	751	15	mutated	mutated	JJ
cord-022561-rv5j1201	751	16	α	α	NN
cord-022561-rv5j1201	751	17	IIb	iib	NN
cord-022561-rv5j1201	751	18	subunit	subunit	NN
cord-022561-rv5j1201	751	19	of	of	IN
cord-022561-rv5j1201	751	20	the	the	DT
cord-022561-rv5j1201	751	21	integrin	integrin	NN
cord-022561-rv5j1201	751	22	α	α	NN
cord-022561-rv5j1201	751	23	IIb	IIb	NNP
cord-022561-rv5j1201	751	24	β	β	XX
cord-022561-rv5j1201	751	25	3	3	CD
cord-022561-rv5j1201	751	26	(	(	-LRB-
cord-022561-rv5j1201	751	27	also	also	RB
cord-022561-rv5j1201	751	28	known	know	VBN
cord-022561-rv5j1201	751	29	as	as	IN
cord-022561-rv5j1201	751	30	glycoprotein	glycoprotein	NN
cord-022561-rv5j1201	751	31	IIb	iib	NN
cord-022561-rv5j1201	751	32	-	-	HYPH
cord-022561-rv5j1201	751	33	IIIa	iiia	NN
cord-022561-rv5j1201	751	34	[	[	-LRB-
cord-022561-rv5j1201	751	35	GPIIb	GPIIb	NNP
cord-022561-rv5j1201	751	36	-	-	HYPH
cord-022561-rv5j1201	751	37	IIIa	IIIa	NNP
cord-022561-rv5j1201	751	38	]	]	-RRB-
cord-022561-rv5j1201	751	39	)	)	-RRB-
cord-022561-rv5j1201	751	40	.	.	.
cord-022561-rv5j1201	752	1	The	the	DT
cord-022561-rv5j1201	752	2	disorder	disorder	NN
cord-022561-rv5j1201	752	3	has	have	VBZ
cord-022561-rv5j1201	752	4	been	be	VBN
cord-022561-rv5j1201	752	5	recognized	recognize	VBN
cord-022561-rv5j1201	752	6	in	in	IN
cord-022561-rv5j1201	752	7	Great	Great	NNP
cord-022561-rv5j1201	752	8	Pyrenees	Pyrenees	NNP
cord-022561-rv5j1201	752	9	and	and	CC
cord-022561-rv5j1201	752	10	otterhound	otterhound	JJ
cord-022561-rv5j1201	752	11	dogs	dog	NNS
cord-022561-rv5j1201	752	12	and	and	CC
cord-022561-rv5j1201	752	13	several	several	JJ
cord-022561-rv5j1201	752	14	horse	horse	NN
cord-022561-rv5j1201	752	15	breeds	breed	NNS
cord-022561-rv5j1201	752	16	,	,	,
cord-022561-rv5j1201	752	17	including	include	VBG
cord-022561-rv5j1201	752	18	a	a	DT
cord-022561-rv5j1201	752	19	quarter	quarter	NN
cord-022561-rv5j1201	752	20	horse	horse	NN
cord-022561-rv5j1201	752	21	,	,	,
cord-022561-rv5j1201	752	22	a	a	DT
cord-022561-rv5j1201	752	23	standardbred	standardbred	NN
cord-022561-rv5j1201	752	24	,	,	,
cord-022561-rv5j1201	752	25	a	a	DT
cord-022561-rv5j1201	752	26	thoroughbred	thoroughbred	NN
cord-022561-rv5j1201	752	27	-	-	HYPH
cord-022561-rv5j1201	752	28	cross	cross	NN
cord-022561-rv5j1201	752	29	,	,	,
cord-022561-rv5j1201	752	30	a	a	DT
cord-022561-rv5j1201	752	31	Peruvian	Peruvian	NNP
cord-022561-rv5j1201	752	32	Paso	Paso	NNP
cord-022561-rv5j1201	752	33	mare	mare	NN
cord-022561-rv5j1201	752	34	,	,	,
cord-022561-rv5j1201	752	35	and	and	CC
cord-022561-rv5j1201	752	36	an	an	DT
cord-022561-rv5j1201	752	37	Oldenburg	Oldenburg	NNP
cord-022561-rv5j1201	752	38	filly	filly	NN
cord-022561-rv5j1201	752	39	.	.	.
cord-022561-rv5j1201	753	1	The	the	DT
cord-022561-rv5j1201	753	2	α	α	NN
cord-022561-rv5j1201	753	3	IIb	iib	NN
cord-022561-rv5j1201	753	4	β	β	XX
cord-022561-rv5j1201	753	5	3	3	CD
cord-022561-rv5j1201	753	6	molecule	molecule	NN
cord-022561-rv5j1201	753	7	has	have	VBZ
cord-022561-rv5j1201	753	8	multiple	multiple	JJ
cord-022561-rv5j1201	753	9	functions	function	NNS
cord-022561-rv5j1201	753	10	but	but	CC
cord-022561-rv5j1201	753	11	is	be	VBZ
cord-022561-rv5j1201	753	12	best	well	RBS
cord-022561-rv5j1201	753	13	known	know	VBN
cord-022561-rv5j1201	753	14	as	as	IN
cord-022561-rv5j1201	753	15	a	a	DT
cord-022561-rv5j1201	753	16	fibrinogen	fibrinogen	NN
cord-022561-rv5j1201	753	17	receptor	receptor	NN
cord-022561-rv5j1201	753	18	that	that	WDT
cord-022561-rv5j1201	753	19	is	be	VBZ
cord-022561-rv5j1201	753	20	essential	essential	JJ
cord-022561-rv5j1201	753	21	for	for	IN
cord-022561-rv5j1201	753	22	normal	normal	JJ
cord-022561-rv5j1201	753	23	platelet	platelet	NN
cord-022561-rv5j1201	753	24	aggregation	aggregation	NN
cord-022561-rv5j1201	753	25	.	.	.
cord-022561-rv5j1201	754	1	Bleeding	bleeding	JJ
cord-022561-rv5j1201	754	2	tendencies	tendency	NNS
cord-022561-rv5j1201	754	3	vary	vary	VBP
cord-022561-rv5j1201	754	4	widely	widely	RB
cord-022561-rv5j1201	754	5	between	between	IN
cord-022561-rv5j1201	754	6	affected	affect	VBN
cord-022561-rv5j1201	754	7	individuals	individual	NNS
cord-022561-rv5j1201	754	8	but	but	CC
cord-022561-rv5j1201	754	9	mainly	mainly	RB
cord-022561-rv5j1201	754	10	occur	occur	VBP
cord-022561-rv5j1201	754	11	on	on	IN
cord-022561-rv5j1201	754	12	mucosal	mucosal	JJ
cord-022561-rv5j1201	754	13	surfaces	surface	NNS
cord-022561-rv5j1201	754	14	.	.	.
cord-022561-rv5j1201	755	1	The	the	DT
cord-022561-rv5j1201	755	2	condition	condition	NN
cord-022561-rv5j1201	755	3	is	be	VBZ
cord-022561-rv5j1201	755	4	characterized	characterize	VBN
cord-022561-rv5j1201	755	5	by	by	IN
cord-022561-rv5j1201	755	6	an	an	DT
cord-022561-rv5j1201	755	7	in	in	FW
cord-022561-rv5j1201	755	8	vitro	vitro	FW
cord-022561-rv5j1201	755	9	lack	lack	NN
cord-022561-rv5j1201	755	10	of	of	IN
cord-022561-rv5j1201	755	11	response	response	NN
cord-022561-rv5j1201	755	12	to	to	IN
cord-022561-rv5j1201	755	13	all	all	DT
cord-022561-rv5j1201	755	14	platelet	platelet	NN
cord-022561-rv5j1201	755	15	agonists	agonist	NNS
cord-022561-rv5j1201	755	16	and	and	CC
cord-022561-rv5j1201	755	17	severely	severely	RB
cord-022561-rv5j1201	755	18	impaired	impaired	JJ
cord-022561-rv5j1201	755	19	clot	clot	NN
cord-022561-rv5j1201	755	20	retraction	retraction	NN
cord-022561-rv5j1201	755	21	(	(	-LRB-
cord-022561-rv5j1201	755	22	i.e.	i.e.	FW
cord-022561-rv5j1201	755	23	,	,	,
cord-022561-rv5j1201	755	24	whole	whole	JJ
cord-022561-rv5j1201	755	25	blood	blood	NN
cord-022561-rv5j1201	755	26	samples	sample	NNS
cord-022561-rv5j1201	755	27	without	without	IN
cord-022561-rv5j1201	755	28	anticoagulant	anticoagulant	NN
cord-022561-rv5j1201	755	29	often	often	RB
cord-022561-rv5j1201	755	30	fail	fail	VBP
cord-022561-rv5j1201	755	31	to	to	TO
cord-022561-rv5j1201	755	32	clot	clot	VB
cord-022561-rv5j1201	755	33	)	)	-RRB-
cord-022561-rv5j1201	755	34	.	.	.
cord-022561-rv5j1201	756	1	Molecular	molecular	JJ
cord-022561-rv5j1201	756	2	testing	testing	NN
cord-022561-rv5j1201	756	3	is	be	VBZ
cord-022561-rv5j1201	756	4	available	available	JJ
cord-022561-rv5j1201	756	5	to	to	TO
cord-022561-rv5j1201	756	6	detect	detect	VB
cord-022561-rv5j1201	756	7	diseased	diseased	JJ
cord-022561-rv5j1201	756	8	or	or	CC
cord-022561-rv5j1201	756	9	carrier	carrier	NN
cord-022561-rv5j1201	756	10	states	state	NNS
cord-022561-rv5j1201	756	11	in	in	IN
cord-022561-rv5j1201	756	12	dogs	dog	NNS
cord-022561-rv5j1201	756	13	and	and	CC
cord-022561-rv5j1201	756	14	horses	horse	NNS
cord-022561-rv5j1201	756	15	.	.	.
cord-022561-rv5j1201	757	1	Thrombopathia	Thrombopathia	NNP
cord-022561-rv5j1201	757	2	.	.	.
cord-022561-rv5j1201	758	1	Calcium	calcium	NN
cord-022561-rv5j1201	758	2	diacylglycerol	diacylglycerol	NN
cord-022561-rv5j1201	758	3	guanine	guanine	NN
cord-022561-rv5j1201	758	4	nucleotide	nucleotide	JJ
cord-022561-rv5j1201	758	5	exchange	exchange	NN
cord-022561-rv5j1201	758	6	factor	factor	NN
cord-022561-rv5j1201	759	1	I	-PRON-	PRP
cord-022561-rv5j1201	759	2	(	(	-LRB-
cord-022561-rv5j1201	759	3	CalDAG	CalDAG	NNP
cord-022561-rv5j1201	759	4	-	-	HYPH
cord-022561-rv5j1201	759	5	GEFI	GEFI	NNP
cord-022561-rv5j1201	759	6	)	)	-RRB-
cord-022561-rv5j1201	759	7	is	be	VBZ
cord-022561-rv5j1201	759	8	a	a	DT
cord-022561-rv5j1201	759	9	molecule	molecule	NN
cord-022561-rv5j1201	759	10	within	within	IN
cord-022561-rv5j1201	759	11	the	the	DT
cord-022561-rv5j1201	759	12	signaling	signal	VBG
cord-022561-rv5j1201	759	13	pathway	pathway	NN
cord-022561-rv5j1201	759	14	that	that	WDT
cord-022561-rv5j1201	759	15	results	result	VBZ
cord-022561-rv5j1201	759	16	in	in	IN
cord-022561-rv5j1201	759	17	platelet	platelet	NN
cord-022561-rv5j1201	759	18	activation	activation	NN
cord-022561-rv5j1201	759	19	in	in	IN
cord-022561-rv5j1201	759	20	response	response	NN
cord-022561-rv5j1201	759	21	to	to	IN
cord-022561-rv5j1201	759	22	platelet	platelet	NN
cord-022561-rv5j1201	759	23	agonists	agonist	NNS
cord-022561-rv5j1201	759	24	.	.	.
cord-022561-rv5j1201	760	1	Mutated	mutated	JJ
cord-022561-rv5j1201	760	2	CalDAG	CalDAG	NNP
cord-022561-rv5j1201	760	3	-	-	HYPH
cord-022561-rv5j1201	760	4	GEFI	GEFI	NNP
cord-022561-rv5j1201	760	5	has	have	VBZ
cord-022561-rv5j1201	760	6	been	be	VBN
cord-022561-rv5j1201	760	7	documented	document	VBN
cord-022561-rv5j1201	760	8	in	in	IN
cord-022561-rv5j1201	760	9	basset	basset	NN
cord-022561-rv5j1201	760	10	hound	hound	NN
cord-022561-rv5j1201	760	11	,	,	,
cord-022561-rv5j1201	760	12	Eskimo	Eskimo	NNP
cord-022561-rv5j1201	760	13	spitz	spitz	NNP
cord-022561-rv5j1201	760	14	,	,	,
cord-022561-rv5j1201	760	15	and	and	CC
cord-022561-rv5j1201	760	16	Landseer	Landseer	NNP
cord-022561-rv5j1201	760	17	dogs	dog	NNS
cord-022561-rv5j1201	760	18	,	,	,
cord-022561-rv5j1201	760	19	and	and	CC
cord-022561-rv5j1201	760	20	Simmental	Simmental	NNP
cord-022561-rv5j1201	760	21	cattle	cattle	NNS
cord-022561-rv5j1201	760	22	.	.	.
cord-022561-rv5j1201	761	1	All	all	DT
cord-022561-rv5j1201	761	2	reported	report	VBN
cord-022561-rv5j1201	761	3	mutations	mutation	NNS
cord-022561-rv5j1201	761	4	have	have	VBP
cord-022561-rv5j1201	761	5	a	a	DT
cord-022561-rv5j1201	761	6	bleeding	bleeding	JJ
cord-022561-rv5j1201	761	7	tendency	tendency	NN
cord-022561-rv5j1201	761	8	.	.	.
cord-022561-rv5j1201	762	1	In	in	IN
cord-022561-rv5j1201	762	2	vitro	vitro	FW
cord-022561-rv5j1201	762	3	platelet	platelet	NN
cord-022561-rv5j1201	762	4	aggregation	aggregation	NN
cord-022561-rv5j1201	762	5	responses	response	NNS
cord-022561-rv5j1201	762	6	to	to	IN
cord-022561-rv5j1201	762	7	platelet	platelet	NN
cord-022561-rv5j1201	762	8	agonists	agonist	NNS
cord-022561-rv5j1201	762	9	,	,	,
cord-022561-rv5j1201	762	10	such	such	JJ
cord-022561-rv5j1201	762	11	as	as	IN
cord-022561-rv5j1201	762	12	ADP	ADP	NNP
cord-022561-rv5j1201	762	13	,	,	,
cord-022561-rv5j1201	762	14	collagen	collagen	NN
cord-022561-rv5j1201	762	15	,	,	,
cord-022561-rv5j1201	762	16	and	and	CC
cord-022561-rv5j1201	762	17	thrombin	thrombin	NN
cord-022561-rv5j1201	762	18	,	,	,
cord-022561-rv5j1201	762	19	are	be	VBP
cord-022561-rv5j1201	762	20	absent	absent	JJ
cord-022561-rv5j1201	762	21	or	or	CC
cord-022561-rv5j1201	762	22	impaired	impaired	JJ
cord-022561-rv5j1201	762	23	.	.	.
cord-022561-rv5j1201	763	1	Information	information	NN
cord-022561-rv5j1201	763	2	on	on	IN
cord-022561-rv5j1201	763	3	this	this	DT
cord-022561-rv5j1201	763	4	topic	topic	NN
cord-022561-rv5j1201	763	5	is	be	VBZ
cord-022561-rv5j1201	763	6	available	available	JJ
cord-022561-rv5j1201	763	7	at	at	IN
cord-022561-rv5j1201	763	8	www.expertconsult.com	www.expertconsult.com	ADD
cord-022561-rv5j1201	763	9	.	.	.
cord-022561-rv5j1201	764	1	Information	information	NN
cord-022561-rv5j1201	764	2	on	on	IN
cord-022561-rv5j1201	764	3	this	this	DT
cord-022561-rv5j1201	764	4	topic	topic	NN
cord-022561-rv5j1201	764	5	is	be	VBZ
cord-022561-rv5j1201	764	6	available	available	JJ
cord-022561-rv5j1201	764	7	at	at	IN
cord-022561-rv5j1201	764	8	www.expertconsult.com	www.expertconsult.com	ADD
cord-022561-rv5j1201	764	9	.	.	.
cord-022561-rv5j1201	765	1	Information	information	NN
cord-022561-rv5j1201	765	2	on	on	IN
cord-022561-rv5j1201	765	3	this	this	DT
cord-022561-rv5j1201	765	4	topic	topic	NN
cord-022561-rv5j1201	765	5	is	be	VBZ
cord-022561-rv5j1201	765	6	available	available	JJ
cord-022561-rv5j1201	765	7	at	at	IN
cord-022561-rv5j1201	765	8	www.expertconsult.com	www.expertconsult.com	ADD
cord-022561-rv5j1201	765	9	.	.	.
cord-022561-rv5j1201	766	1	Oxidative	oxidative	JJ
cord-022561-rv5j1201	766	2	Agents	agent	NNS
cord-022561-rv5j1201	766	3	.	.	.
cord-022561-rv5j1201	767	1	A	a	DT
cord-022561-rv5j1201	767	2	variety	variety	NN
cord-022561-rv5j1201	767	3	of	of	IN
cord-022561-rv5j1201	767	4	oxidative	oxidative	JJ
cord-022561-rv5j1201	767	5	toxins	toxin	NNS
cord-022561-rv5j1201	767	6	cause	cause	VBP
cord-022561-rv5j1201	767	7	hemolytic	hemolytic	JJ
cord-022561-rv5j1201	767	8	anemia	anemia	NN
cord-022561-rv5j1201	767	9	and/or	and/or	CC
cord-022561-rv5j1201	767	10	methemoglobinemia	methemoglobinemia	NN
cord-022561-rv5j1201	767	11	in	in	IN
cord-022561-rv5j1201	767	12	domestic	domestic	JJ
cord-022561-rv5j1201	767	13	species	specie	NNS
cord-022561-rv5j1201	767	14	.	.	.
cord-022561-rv5j1201	768	1	More	more	RBR
cord-022561-rv5j1201	768	2	common	common	JJ
cord-022561-rv5j1201	768	3	or	or	CC
cord-022561-rv5j1201	768	4	well	well	RB
cord-022561-rv5j1201	768	5	-	-	HYPH
cord-022561-rv5j1201	768	6	characterized	characterize	VBN
cord-022561-rv5j1201	768	7	oxidants	oxidant	NNS
cord-022561-rv5j1201	768	8	are	be	VBP
cord-022561-rv5j1201	768	9	listed	list	VBN
cord-022561-rv5j1201	768	10	here	here	RB
cord-022561-rv5j1201	768	11	:	:	:
cord-022561-rv5j1201	769	1	•	•	NNP
cord-022561-rv5j1201	770	1	Horses	horse	NNS
cord-022561-rv5j1201	770	2	-	-	:
cord-022561-rv5j1201	770	3	Acer	Acer	NNP
cord-022561-rv5j1201	770	4	rubrum	rubrum	NN
cord-022561-rv5j1201	770	5	(	(	-LRB-
cord-022561-rv5j1201	770	6	red	red	JJ
cord-022561-rv5j1201	770	7	maple	maple	NN
cord-022561-rv5j1201	770	8	)	)	-RRB-
cord-022561-rv5j1201	771	1	•	•	NNP
cord-022561-rv5j1201	772	1	Ruminants	ruminant	NNS
cord-022561-rv5j1201	772	2	-	-	HYPH
cord-022561-rv5j1201	772	3	Brassica	Brassica	NNP
cord-022561-rv5j1201	772	4	spp	spp	NNS
cord-022561-rv5j1201	772	5	.	.	.
cord-022561-rv5j1201	773	1	(	(	-LRB-
cord-022561-rv5j1201	773	2	cabbage	cabbage	NN
cord-022561-rv5j1201	773	3	,	,	,
cord-022561-rv5j1201	773	4	kale	kale	NN
cord-022561-rv5j1201	773	5	,	,	,
cord-022561-rv5j1201	773	6	and	and	CC
cord-022561-rv5j1201	773	7	rape	rape	NN
cord-022561-rv5j1201	773	8	)	)	-RRB-
cord-022561-rv5j1201	773	9	,	,	,
cord-022561-rv5j1201	773	10	copper	copper	NN
cord-022561-rv5j1201	773	11	hypersegmented	hypersegmente	VBN
cord-022561-rv5j1201	773	12	neutrophils	neutrophil	NNS
cord-022561-rv5j1201	773	13	,	,	,
cord-022561-rv5j1201	773	14	due	due	IN
cord-022561-rv5j1201	773	15	to	to	IN
cord-022561-rv5j1201	773	16	neutrophil	neutrophil	NN
cord-022561-rv5j1201	773	17	aging	aging	NN
cord-022561-rv5j1201	773	18	within	within	IN
cord-022561-rv5j1201	773	19	blood	blood	NN
cord-022561-rv5j1201	773	20	vessels	vessel	NNS
cord-022561-rv5j1201	773	21	(	(	-LRB-
cord-022561-rv5j1201	773	22	Fig	Fig	NNP
cord-022561-rv5j1201	773	23	.	.	.
cord-022561-rv5j1201	773	24	13	13	CD
cord-022561-rv5j1201	773	25	-	-	SYM
cord-022561-rv5j1201	773	26	22	22	CD
cord-022561-rv5j1201	773	27	)	)	-RRB-
cord-022561-rv5j1201	773	28	.	.	.
cord-022561-rv5j1201	774	1	These	these	DT
cord-022561-rv5j1201	774	2	animals	animal	NNS
cord-022561-rv5j1201	774	3	are	be	VBP
cord-022561-rv5j1201	774	4	highly	highly	RB
cord-022561-rv5j1201	774	5	susceptible	susceptible	JJ
cord-022561-rv5j1201	774	6	to	to	IN
cord-022561-rv5j1201	774	7	infections	infection	NNS
cord-022561-rv5j1201	774	8	and	and	CC
cord-022561-rv5j1201	774	9	usually	usually	RB
cord-022561-rv5j1201	774	10	die	die	VB
cord-022561-rv5j1201	774	11	at	at	IN
cord-022561-rv5j1201	774	12	a	a	DT
cord-022561-rv5j1201	774	13	young	young	JJ
cord-022561-rv5j1201	774	14	age	age	NN
cord-022561-rv5j1201	774	15	.	.	.
cord-022561-rv5j1201	775	1	Pelger	Pelger	NNP
cord-022561-rv5j1201	775	2	-	-	HYPH
cord-022561-rv5j1201	775	3	Huët	Huët	NNP
cord-022561-rv5j1201	775	4	Anomaly	Anomaly	NNP
cord-022561-rv5j1201	775	5	.	.	.
cord-022561-rv5j1201	776	1	Pelger	Pelger	NNP
cord-022561-rv5j1201	776	2	-	-	HYPH
cord-022561-rv5j1201	776	3	Huët	Huët	NNP
cord-022561-rv5j1201	776	4	anomaly	anomaly	NN
cord-022561-rv5j1201	776	5	(	(	-LRB-
cord-022561-rv5j1201	776	6	PHA	PHA	NNP
cord-022561-rv5j1201	776	7	)	)	-RRB-
cord-022561-rv5j1201	776	8	is	be	VBZ
cord-022561-rv5j1201	776	9	a	a	DT
cord-022561-rv5j1201	776	10	condition	condition	NN
cord-022561-rv5j1201	776	11	of	of	IN
cord-022561-rv5j1201	776	12	hyposegmented	hyposegmented	JJ
cord-022561-rv5j1201	776	13	granulocytes	granulocyte	NNS
cord-022561-rv5j1201	776	14	due	due	IN
cord-022561-rv5j1201	776	15	to	to	IN
cord-022561-rv5j1201	776	16	a	a	DT
cord-022561-rv5j1201	776	17	lamin	lamin	NN
cord-022561-rv5j1201	776	18	B	B	NNP
cord-022561-rv5j1201	776	19	receptor	receptor	NN
cord-022561-rv5j1201	776	20	mutation	mutation	NN
cord-022561-rv5j1201	776	21	.	.	.
cord-022561-rv5j1201	777	1	It	-PRON-	PRP
cord-022561-rv5j1201	777	2	has	have	VBZ
cord-022561-rv5j1201	777	3	been	be	VBN
cord-022561-rv5j1201	777	4	described	describe	VBN
cord-022561-rv5j1201	777	5	in	in	IN
cord-022561-rv5j1201	777	6	dogs	dog	NNS
cord-022561-rv5j1201	777	7	,	,	,
cord-022561-rv5j1201	777	8	cats	cat	NNS
cord-022561-rv5j1201	777	9	,	,	,
cord-022561-rv5j1201	777	10	horses	horse	NNS
cord-022561-rv5j1201	777	11	,	,	,
cord-022561-rv5j1201	777	12	and	and	CC
cord-022561-rv5j1201	777	13	rabbits	rabbit	NNS
cord-022561-rv5j1201	777	14	,	,	,
cord-022561-rv5j1201	777	15	especially	especially	RB
cord-022561-rv5j1201	777	16	in	in	IN
cord-022561-rv5j1201	777	17	certain	certain	JJ
cord-022561-rv5j1201	777	18	breeds	breed	NNS
cord-022561-rv5j1201	777	19	.	.	.
cord-022561-rv5j1201	778	1	In	in	IN
cord-022561-rv5j1201	778	2	Australian	australian	JJ
cord-022561-rv5j1201	778	3	shepherd	shepherd	NN
cord-022561-rv5j1201	778	4	dogs	dog	VBZ
cord-022561-rv5j1201	778	5	the	the	DT
cord-022561-rv5j1201	778	6	mode	mode	NN
cord-022561-rv5j1201	778	7	of	of	IN
cord-022561-rv5j1201	778	8	inheritance	inheritance	NN
cord-022561-rv5j1201	778	9	is	be	VBZ
cord-022561-rv5j1201	778	10	autosomal	autosomal	JJ
cord-022561-rv5j1201	778	11	dominant	dominant	JJ
cord-022561-rv5j1201	778	12	with	with	IN
cord-022561-rv5j1201	778	13	incomplete	incomplete	JJ
cord-022561-rv5j1201	778	14	penetrance	penetrance	NN
cord-022561-rv5j1201	778	15	.	.	.
cord-022561-rv5j1201	779	1	Most	Most	JJS
cord-022561-rv5j1201	779	2	cases	case	NNS
cord-022561-rv5j1201	779	3	of	of	IN
cord-022561-rv5j1201	779	4	Pelger	Pelger	NNP
cord-022561-rv5j1201	779	5	-	-	HYPH
cord-022561-rv5j1201	779	6	Huët	Huët	NNP
cord-022561-rv5j1201	779	7	anomaly	anomaly	NN
cord-022561-rv5j1201	779	8	are	be	VBP
cord-022561-rv5j1201	779	9	the	the	DT
cord-022561-rv5j1201	779	10	heterozygous	heterozygous	JJ
cord-022561-rv5j1201	779	11	form	form	NN
cord-022561-rv5j1201	779	12	and	and	CC
cord-022561-rv5j1201	779	13	of	of	IN
cord-022561-rv5j1201	779	14	no	no	DT
cord-022561-rv5j1201	779	15	clinical	clinical	JJ
cord-022561-rv5j1201	779	16	significance	significance	NN
cord-022561-rv5j1201	779	17	.	.	.
cord-022561-rv5j1201	780	1	However	however	RB
cord-022561-rv5j1201	780	2	,	,	,
cord-022561-rv5j1201	780	3	skeletal	skeletal	JJ
cord-022561-rv5j1201	780	4	abnormalities	abnormality	NNS
cord-022561-rv5j1201	780	5	,	,	,
cord-022561-rv5j1201	780	6	stillbirths	stillbirth	NNS
cord-022561-rv5j1201	780	7	,	,	,
cord-022561-rv5j1201	780	8	and/or	and/or	CC
cord-022561-rv5j1201	780	9	early	early	JJ
cord-022561-rv5j1201	780	10	mortality	mortality	NN
cord-022561-rv5j1201	780	11	may	may	MD
cord-022561-rv5j1201	780	12	accompany	accompany	VB
cord-022561-rv5j1201	780	13	Pelger	Pelger	NNP
cord-022561-rv5j1201	780	14	-	-	HYPH
cord-022561-rv5j1201	780	15	Huët	Huët	NNP
cord-022561-rv5j1201	780	16	anomaly	anomaly	NN
cord-022561-rv5j1201	780	17	in	in	IN
cord-022561-rv5j1201	780	18	rabbits	rabbit	NNS
cord-022561-rv5j1201	780	19	and	and	CC
cord-022561-rv5j1201	780	20	cats	cat	NNS
cord-022561-rv5j1201	780	21	,	,	,
cord-022561-rv5j1201	780	22	especially	especially	RB
cord-022561-rv5j1201	780	23	homozygotes	homozygote	NNS
cord-022561-rv5j1201	780	24	.	.	.
cord-022561-rv5j1201	781	1	In	in	IN
cord-022561-rv5j1201	781	2	Pelger	Pelger	NNP
cord-022561-rv5j1201	781	3	-	-	HYPH
cord-022561-rv5j1201	781	4	Huët	Huët	NNP
cord-022561-rv5j1201	781	5	anomaly	anomaly	NN
cord-022561-rv5j1201	781	6	the	the	DT
cord-022561-rv5j1201	781	7	nuclei	nucleus	NNS
cord-022561-rv5j1201	781	8	of	of	IN
cord-022561-rv5j1201	781	9	neutrophils	neutrophil	NNS
cord-022561-rv5j1201	781	10	,	,	,
cord-022561-rv5j1201	781	11	eosinophils	eosinophil	NNS
cord-022561-rv5j1201	781	12	,	,	,
cord-022561-rv5j1201	781	13	and	and	CC
cord-022561-rv5j1201	781	14	basophils	basophil	NNS
cord-022561-rv5j1201	781	15	fail	fail	VBP
cord-022561-rv5j1201	781	16	to	to	IN
cord-022561-rv5j1201	781	17	segment	segment	NN
cord-022561-rv5j1201	781	18	,	,	,
cord-022561-rv5j1201	781	19	resulting	result	VBG
cord-022561-rv5j1201	781	20	in	in	IN
cord-022561-rv5j1201	781	21	band	band	NN
cord-022561-rv5j1201	781	22	-	-	HYPH
cord-022561-rv5j1201	781	23	shaped	shape	VBN
cord-022561-rv5j1201	781	24	,	,	,
cord-022561-rv5j1201	781	25	bean	bean	NN
cord-022561-rv5j1201	781	26	-	-	HYPH
cord-022561-rv5j1201	781	27	shaped	shape	VBN
cord-022561-rv5j1201	781	28	,	,	,
cord-022561-rv5j1201	781	29	or	or	CC
cord-022561-rv5j1201	781	30	round	round	JJ
cord-022561-rv5j1201	781	31	nuclei	nucleus	NNS
cord-022561-rv5j1201	781	32	.	.	.
cord-022561-rv5j1201	782	1	Although	although	IN
cord-022561-rv5j1201	782	2	the	the	DT
cord-022561-rv5j1201	782	3	nuclear	nuclear	JJ
cord-022561-rv5j1201	782	4	shape	shape	NN
cord-022561-rv5j1201	782	5	is	be	VBZ
cord-022561-rv5j1201	782	6	similar	similar	JJ
cord-022561-rv5j1201	782	7	to	to	IN
cord-022561-rv5j1201	782	8	that	that	DT
cord-022561-rv5j1201	782	9	of	of	IN
cord-022561-rv5j1201	782	10	an	an	DT
cord-022561-rv5j1201	782	11	inflammatory	inflammatory	JJ
cord-022561-rv5j1201	782	12	left	left	JJ
cord-022561-rv5j1201	782	13	shift	shift	NN
cord-022561-rv5j1201	782	14	,	,	,
cord-022561-rv5j1201	782	15	healthy	healthy	JJ
cord-022561-rv5j1201	782	16	animals	animal	NNS
cord-022561-rv5j1201	782	17	with	with	IN
cord-022561-rv5j1201	782	18	Pelger	Pelger	NNP
cord-022561-rv5j1201	782	19	-	-	HYPH
cord-022561-rv5j1201	782	20	Huët	Huët	NNP
cord-022561-rv5j1201	782	21	anomaly	anomaly	NN
cord-022561-rv5j1201	782	22	do	do	VBP
cord-022561-rv5j1201	782	23	not	not	RB
cord-022561-rv5j1201	782	24	have	have	VB
cord-022561-rv5j1201	782	25	clinical	clinical	JJ
cord-022561-rv5j1201	782	26	signs	sign	NNS
cord-022561-rv5j1201	782	27	or	or	CC
cord-022561-rv5j1201	782	28	other	other	JJ
cord-022561-rv5j1201	782	29	laboratory	laboratory	NN
cord-022561-rv5j1201	782	30	findings	finding	NNS
cord-022561-rv5j1201	782	31	indicating	indicate	VBG
cord-022561-rv5j1201	782	32	inflammation	inflammation	NN
cord-022561-rv5j1201	782	33	.	.	.
cord-022561-rv5j1201	783	1	For	for	IN
cord-022561-rv5j1201	783	2	example	example	NN
cord-022561-rv5j1201	783	3	,	,	,
cord-022561-rv5j1201	783	4	neutrophils	neutrophil	NNS
cord-022561-rv5j1201	783	5	in	in	IN
cord-022561-rv5j1201	783	6	healthy	healthy	JJ
cord-022561-rv5j1201	783	7	animals	animal	NNS
cord-022561-rv5j1201	783	8	with	with	IN
cord-022561-rv5j1201	783	9	Pelger	Pelger	NNP
cord-022561-rv5j1201	783	10	-	-	HYPH
cord-022561-rv5j1201	783	11	Huët	Huët	NNP
cord-022561-rv5j1201	783	12	anomaly	anomaly	NN
cord-022561-rv5j1201	783	13	have	have	VBP
cord-022561-rv5j1201	783	14	mature	mature	JJ
cord-022561-rv5j1201	783	15	(	(	-LRB-
cord-022561-rv5j1201	783	16	clumped	clumped	JJ
cord-022561-rv5j1201	783	17	)	)	-RRB-
cord-022561-rv5j1201	783	18	chromatin	chromatin	NN
cord-022561-rv5j1201	783	19	and	and	CC
cord-022561-rv5j1201	783	20	do	do	VBP
cord-022561-rv5j1201	783	21	not	not	RB
cord-022561-rv5j1201	783	22	show	show	VB
cord-022561-rv5j1201	783	23	signs	sign	NNS
cord-022561-rv5j1201	783	24	of	of	IN
cord-022561-rv5j1201	783	25	toxicity	toxicity	NN
cord-022561-rv5j1201	783	26	(	(	-LRB-
cord-022561-rv5j1201	783	27	Fig	Fig	NNP
cord-022561-rv5j1201	783	28	.	.	.
cord-022561-rv5j1201	783	29	13	13	CD
cord-022561-rv5j1201	783	30	-	-	SYM
cord-022561-rv5j1201	783	31	23	23	CD
cord-022561-rv5j1201	783	32	)	)	-RRB-
cord-022561-rv5j1201	783	33	.	.	.
cord-022561-rv5j1201	784	1	An	an	DT
cord-022561-rv5j1201	784	2	acquired	acquire	VBN
cord-022561-rv5j1201	784	3	,	,	,
cord-022561-rv5j1201	784	4	reversible	reversible	JJ
cord-022561-rv5j1201	784	5	condition	condition	NN
cord-022561-rv5j1201	784	6	mimicking	mimic	VBG
cord-022561-rv5j1201	784	7	Pelger	Pelger	NNP
cord-022561-rv5j1201	784	8	-	-	HYPH
cord-022561-rv5j1201	784	9	Huët	Huët	NNP
cord-022561-rv5j1201	784	10	anomaly	anomaly	NN
cord-022561-rv5j1201	784	11	,	,	,
cord-022561-rv5j1201	784	12	known	know	VBN
cord-022561-rv5j1201	784	13	as	as	IN
cord-022561-rv5j1201	784	14	pseudo	pseudo	JJ
cord-022561-rv5j1201	784	15	-	-	HYPH
cord-022561-rv5j1201	784	16	Pelger	Pelger	NNP
cord-022561-rv5j1201	784	17	-	-	HYPH
cord-022561-rv5j1201	784	18	Huët	Huët	NNP
cord-022561-rv5j1201	784	19	anomaly	anomaly	NN
cord-022561-rv5j1201	784	20	,	,	,
cord-022561-rv5j1201	784	21	is	be	VBZ
cord-022561-rv5j1201	784	22	occasionally	occasionally	RB
cord-022561-rv5j1201	784	23	noted	note	VBN
cord-022561-rv5j1201	784	24	in	in	IN
cord-022561-rv5j1201	784	25	animals	animal	NNS
cord-022561-rv5j1201	784	26	with	with	IN
cord-022561-rv5j1201	784	27	infectious	infectious	JJ
cord-022561-rv5j1201	784	28	disease	disease	NN
cord-022561-rv5j1201	784	29	,	,	,
cord-022561-rv5j1201	784	30	neoplasia	neoplasia	NN
cord-022561-rv5j1201	784	31	,	,	,
cord-022561-rv5j1201	784	32	or	or	CC
cord-022561-rv5j1201	784	33	drug	drug	NNP
cord-022561-rv5j1201	784	34	administration	administration	NN
cord-022561-rv5j1201	784	35	.	.	.
cord-022561-rv5j1201	785	1	Chédiak	Chédiak	NNP
cord-022561-rv5j1201	785	2	-	-	HYPH
cord-022561-rv5j1201	785	3	Higashi	Higashi	NNP
cord-022561-rv5j1201	785	4	Syndrome	Syndrome	NNP
cord-022561-rv5j1201	785	5	.	.	.
cord-022561-rv5j1201	786	1	Chédiak	Chédiak	NNP
cord-022561-rv5j1201	786	2	-	-	HYPH
cord-022561-rv5j1201	786	3	Higashi	Higashi	NNP
cord-022561-rv5j1201	786	4	syndrome	syndrome	NN
cord-022561-rv5j1201	786	5	(	(	-LRB-
cord-022561-rv5j1201	786	6	CHS	CHS	NNP
cord-022561-rv5j1201	786	7	)	)	-RRB-
cord-022561-rv5j1201	786	8	is	be	VBZ
cord-022561-rv5j1201	786	9	a	a	DT
cord-022561-rv5j1201	786	10	rare	rare	JJ
cord-022561-rv5j1201	786	11	autosomal	autosomal	JJ
cord-022561-rv5j1201	786	12	recessive	recessive	JJ
cord-022561-rv5j1201	786	13	defect	defect	NN
cord-022561-rv5j1201	786	14	in	in	IN
cord-022561-rv5j1201	786	15	the	the	DT
cord-022561-rv5j1201	786	16	lysosomal	lysosomal	JJ
cord-022561-rv5j1201	786	17	trafficking	traffic	VBG
cord-022561-rv5j1201	786	18	regulator	regulator	NN
cord-022561-rv5j1201	786	19	(	(	-LRB-
cord-022561-rv5j1201	786	20	LYST	LYST	NNP
cord-022561-rv5j1201	786	21	)	)	-RRB-
cord-022561-rv5j1201	786	22	protein	protein	NN
cord-022561-rv5j1201	786	23	.	.	.
cord-022561-rv5j1201	787	1	The	the	DT
cord-022561-rv5j1201	787	2	syndrome	syndrome	NN
cord-022561-rv5j1201	787	3	has	have	VBZ
cord-022561-rv5j1201	787	4	been	be	VBN
cord-022561-rv5j1201	787	5	identified	identify	VBN
cord-022561-rv5j1201	787	6	in	in	IN
cord-022561-rv5j1201	787	7	Hereford	Hereford	NNP
cord-022561-rv5j1201	787	8	,	,	,
cord-022561-rv5j1201	787	9	Brangus	Brangus	NNP
cord-022561-rv5j1201	787	10	,	,	,
cord-022561-rv5j1201	787	11	and	and	CC
cord-022561-rv5j1201	787	12	Japanese	japanese	JJ
cord-022561-rv5j1201	787	13	black	black	JJ
cord-022561-rv5j1201	787	14	cattle	cattle	NNS
cord-022561-rv5j1201	787	15	,	,	,
cord-022561-rv5j1201	787	16	Persian	persian	JJ
cord-022561-rv5j1201	787	17	cats	cat	NNS
cord-022561-rv5j1201	787	18	,	,	,
cord-022561-rv5j1201	787	19	and	and	CC
cord-022561-rv5j1201	787	20	several	several	JJ
cord-022561-rv5j1201	787	21	nondomestic	nondomestic	JJ
cord-022561-rv5j1201	787	22	species	specie	NNS
cord-022561-rv5j1201	787	23	.	.	.
cord-022561-rv5j1201	788	1	The	the	DT
cord-022561-rv5j1201	788	2	defective	defective	JJ
cord-022561-rv5j1201	788	3	LYST	LYST	NNP
cord-022561-rv5j1201	788	4	protein	protein	NN
cord-022561-rv5j1201	788	5	results	result	NNS
cord-022561-rv5j1201	788	6	in	in	IN
cord-022561-rv5j1201	788	7	granule	granule	NN
cord-022561-rv5j1201	788	8	fusion	fusion	NN
cord-022561-rv5j1201	788	9	in	in	IN
cord-022561-rv5j1201	788	10	multiple	multiple	JJ
cord-022561-rv5j1201	788	11	cell	cell	NN
cord-022561-rv5j1201	788	12	types	type	NNS
cord-022561-rv5j1201	788	13	,	,	,
cord-022561-rv5j1201	788	14	including	include	VBG
cord-022561-rv5j1201	788	15	granulocytes	granulocyte	NNS
cord-022561-rv5j1201	788	16	,	,	,
cord-022561-rv5j1201	788	17	platelets	platelet	NNS
cord-022561-rv5j1201	788	18	,	,	,
cord-022561-rv5j1201	788	19	and	and	CC
cord-022561-rv5j1201	788	20	melanocytes	melanocyte	NNS
cord-022561-rv5j1201	788	21	,	,	,
cord-022561-rv5j1201	788	22	as	as	RB
cord-022561-rv5j1201	788	23	well	well	RB
cord-022561-rv5j1201	788	24	as	as	IN
cord-022561-rv5j1201	788	25	abnormal	abnormal	JJ
cord-022561-rv5j1201	788	26	cell	cell	NN
cord-022561-rv5j1201	788	27	function	function	NN
cord-022561-rv5j1201	788	28	.	.	.
cord-022561-rv5j1201	789	1	Individuals	individual	NNS
cord-022561-rv5j1201	789	2	with	with	IN
cord-022561-rv5j1201	789	3	Chédiak	Chédiak	NNP
cord-022561-rv5j1201	789	4	-	-	HYPH
cord-022561-rv5j1201	789	5	Higashi	Higashi	NNP
cord-022561-rv5j1201	789	6	syndrome	syndrome	NN
cord-022561-rv5j1201	789	7	have	have	VBP
cord-022561-rv5j1201	789	8	severely	severely	RB
cord-022561-rv5j1201	789	9	impaired	impair	VBN
cord-022561-rv5j1201	789	10	cellular	cellular	JJ
cord-022561-rv5j1201	789	11	innate	innate	JJ
cord-022561-rv5j1201	789	12	immunity	immunity	NN
cord-022561-rv5j1201	789	13	because	because	IN
cord-022561-rv5j1201	789	14	of	of	IN
cord-022561-rv5j1201	789	15	neutropenia	neutropenia	NN
cord-022561-rv5j1201	789	16	,	,	,
cord-022561-rv5j1201	789	17	impaired	impaired	JJ
cord-022561-rv5j1201	789	18	leukocyte	leukocyte	NN
cord-022561-rv5j1201	789	19	chemotaxis	chemotaxis	NN
cord-022561-rv5j1201	789	20	,	,	,
cord-022561-rv5j1201	789	21	and	and	CC
cord-022561-rv5j1201	789	22	impaired	impaired	JJ
cord-022561-rv5j1201	789	23	killing	killing	NN
cord-022561-rv5j1201	789	24	by	by	IN
cord-022561-rv5j1201	789	25	granulocytes	granulocyte	NNS
cord-022561-rv5j1201	789	26	and	and	CC
cord-022561-rv5j1201	789	27	cytotoxic	cytotoxic	JJ
cord-022561-rv5j1201	789	28	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	789	29	.	.	.
cord-022561-rv5j1201	790	1	Platelets	platelet	NNS
cord-022561-rv5j1201	790	2	lack	lack	VBP
cord-022561-rv5j1201	790	3	the	the	DT
cord-022561-rv5j1201	790	4	dense	dense	JJ
cord-022561-rv5j1201	790	5	granules	granule	NNS
cord-022561-rv5j1201	790	6	that	that	WDT
cord-022561-rv5j1201	790	7	normally	normally	RB
cord-022561-rv5j1201	790	8	contain	contain	VBP
cord-022561-rv5j1201	790	9	key	key	JJ
cord-022561-rv5j1201	790	10	bioactive	bioactive	JJ
cord-022561-rv5j1201	790	11	molecules	molecule	NNS
cord-022561-rv5j1201	790	12	involved	involve	VBN
cord-022561-rv5j1201	790	13	in	in	IN
cord-022561-rv5j1201	790	14	hemostasis	hemostasis	NN
cord-022561-rv5j1201	790	15	,	,	,
cord-022561-rv5j1201	790	16	including	include	VBG
cord-022561-rv5j1201	790	17	platelet	platelet	NN
cord-022561-rv5j1201	790	18	agonists	agonist	NNS
cord-022561-rv5j1201	790	19	,	,	,
cord-022561-rv5j1201	790	20	such	such	JJ
cord-022561-rv5j1201	790	21	as	as	IN
cord-022561-rv5j1201	790	22	ADP	ADP	NNP
cord-022561-rv5j1201	790	23	and	and	CC
cord-022561-rv5j1201	790	24	serotonin	serotonin	NN
cord-022561-rv5j1201	790	25	.	.	.
cord-022561-rv5j1201	791	1	In	in	IN
cord-022561-rv5j1201	791	2	vitro	vitro	FW
cord-022561-rv5j1201	791	3	platelet	platelet	NN
cord-022561-rv5j1201	791	4	aggregation	aggregation	NN
cord-022561-rv5j1201	791	5	is	be	VBZ
cord-022561-rv5j1201	791	6	severely	severely	RB
cord-022561-rv5j1201	791	7	impaired	impaired	JJ
cord-022561-rv5j1201	791	8	.	.	.
cord-022561-rv5j1201	792	1	As	as	IN
cord-022561-rv5j1201	792	2	a	a	DT
cord-022561-rv5j1201	792	3	result	result	NN
cord-022561-rv5j1201	792	4	,	,	,
cord-022561-rv5j1201	792	5	animals	animal	NNS
cord-022561-rv5j1201	792	6	with	with	IN
cord-022561-rv5j1201	792	7	Chédiak	Chédiak	NNP
cord-022561-rv5j1201	792	8	-	-	HYPH
cord-022561-rv5j1201	792	9	Higashi	Higashi	NNP
cord-022561-rv5j1201	793	1	746.e1	746.e1	CD
cord-022561-rv5j1201	794	1	CHAPTER	chapter	NN
cord-022561-rv5j1201	794	2	13	13	CD
cord-022561-rv5j1201	794	3	Bone	Bone	NNP
cord-022561-rv5j1201	794	4	Marrow	Marrow	NNP
cord-022561-rv5j1201	794	5	,	,	,
cord-022561-rv5j1201	794	6	Blood	blood	NN
cord-022561-rv5j1201	794	7	Cells	cell	NNS
cord-022561-rv5j1201	794	8	,	,	,
cord-022561-rv5j1201	794	9	and	and	CC
cord-022561-rv5j1201	794	10	the	the	DT
cord-022561-rv5j1201	794	11	Lymphoid	Lymphoid	NNP
cord-022561-rv5j1201	794	12	/	/	SYM
cord-022561-rv5j1201	794	13	Lymphatic	Lymphatic	NNP
cord-022561-rv5j1201	794	14	System	System	NNP
cord-022561-rv5j1201	794	15	von	von	NNP
cord-022561-rv5j1201	794	16	Willebrand	Willebrand	NNP
cord-022561-rv5j1201	794	17	disease	disease	NN
cord-022561-rv5j1201	794	18	(	(	-LRB-
cord-022561-rv5j1201	794	19	vWD	vwd	NN
cord-022561-rv5j1201	794	20	)	)	-RRB-
cord-022561-rv5j1201	794	21	is	be	VBZ
cord-022561-rv5j1201	794	22	the	the	DT
cord-022561-rv5j1201	794	23	most	most	RBS
cord-022561-rv5j1201	794	24	common	common	JJ
cord-022561-rv5j1201	794	25	canine	canine	JJ
cord-022561-rv5j1201	794	26	hereditary	hereditary	JJ
cord-022561-rv5j1201	794	27	bleeding	bleed	VBG
cord-022561-rv5j1201	794	28	disorder	disorder	NN
cord-022561-rv5j1201	794	29	and	and	CC
cord-022561-rv5j1201	794	30	has	have	VBZ
cord-022561-rv5j1201	794	31	also	also	RB
cord-022561-rv5j1201	794	32	been	be	VBN
cord-022561-rv5j1201	794	33	described	describe	VBN
cord-022561-rv5j1201	794	34	in	in	IN
cord-022561-rv5j1201	794	35	many	many	JJ
cord-022561-rv5j1201	794	36	other	other	JJ
cord-022561-rv5j1201	794	37	domestic	domestic	JJ
cord-022561-rv5j1201	794	38	species	specie	NNS
cord-022561-rv5j1201	794	39	.	.	.
cord-022561-rv5j1201	795	1	The	the	DT
cord-022561-rv5j1201	795	2	disease	disease	NN
cord-022561-rv5j1201	795	3	actually	actually	RB
cord-022561-rv5j1201	795	4	refers	refer	VBZ
cord-022561-rv5j1201	795	5	to	to	IN
cord-022561-rv5j1201	795	6	a	a	DT
cord-022561-rv5j1201	795	7	group	group	NN
cord-022561-rv5j1201	795	8	of	of	IN
cord-022561-rv5j1201	795	9	inherited	inherit	VBN
cord-022561-rv5j1201	795	10	conditions	condition	NNS
cord-022561-rv5j1201	795	11	characterized	characterize	VBN
cord-022561-rv5j1201	795	12	by	by	IN
cord-022561-rv5j1201	795	13	a	a	DT
cord-022561-rv5j1201	795	14	quantitative	quantitative	JJ
cord-022561-rv5j1201	795	15	or	or	CC
cord-022561-rv5j1201	795	16	qualitative	qualitative	JJ
cord-022561-rv5j1201	795	17	deficiency	deficiency	NN
cord-022561-rv5j1201	795	18	of	of	IN
cord-022561-rv5j1201	795	19	vWF	vWF	NNP
cord-022561-rv5j1201	795	20	.	.	.
cord-022561-rv5j1201	796	1	This	this	DT
cord-022561-rv5j1201	796	2	factor	factor	NN
cord-022561-rv5j1201	796	3	is	be	VBZ
cord-022561-rv5j1201	796	4	a	a	DT
cord-022561-rv5j1201	796	5	multimeric	multimeric	JJ
cord-022561-rv5j1201	796	6	glycoprotein	glycoprotein	NN
cord-022561-rv5j1201	796	7	that	that	WDT
cord-022561-rv5j1201	796	8	is	be	VBZ
cord-022561-rv5j1201	796	9	stored	store	VBN
cord-022561-rv5j1201	796	10	in	in	IN
cord-022561-rv5j1201	796	11	platelet	platelet	NN
cord-022561-rv5j1201	796	12	α	α	NN
cord-022561-rv5j1201	796	13	-	-	HYPH
cord-022561-rv5j1201	796	14	granules	granule	NNS
cord-022561-rv5j1201	796	15	and	and	CC
cord-022561-rv5j1201	796	16	endothelial	endothelial	JJ
cord-022561-rv5j1201	796	17	cells	cell	NNS
cord-022561-rv5j1201	796	18	and	and	CC
cord-022561-rv5j1201	796	19	circulates	circulate	VBZ
cord-022561-rv5j1201	796	20	as	as	IN
cord-022561-rv5j1201	796	21	a	a	DT
cord-022561-rv5j1201	796	22	complex	complex	NN
cord-022561-rv5j1201	796	23	with	with	IN
cord-022561-rv5j1201	796	24	coagulation	coagulation	NN
cord-022561-rv5j1201	796	25	factor	factor	NN
cord-022561-rv5j1201	796	26	VIII	VIII	NNP
cord-022561-rv5j1201	796	27	.	.	.
cord-022561-rv5j1201	797	1	Its	-PRON-	PRP$
cord-022561-rv5j1201	797	2	primary	primary	JJ
cord-022561-rv5j1201	797	3	functions	function	NNS
cord-022561-rv5j1201	797	4	are	be	VBP
cord-022561-rv5j1201	797	5	to	to	TO
cord-022561-rv5j1201	797	6	stabilize	stabilize	VB
cord-022561-rv5j1201	797	7	factor	factor	NN
cord-022561-rv5j1201	797	8	VIII	VIII	NNP
cord-022561-rv5j1201	797	9	and	and	CC
cord-022561-rv5j1201	797	10	mediate	mediate	VB
cord-022561-rv5j1201	797	11	platelet	platelet	NN
cord-022561-rv5j1201	797	12	binding	bind	VBG
cord-022561-rv5j1201	797	13	to	to	IN
cord-022561-rv5j1201	797	14	other	other	JJ
cord-022561-rv5j1201	797	15	platelets	platelet	NNS
cord-022561-rv5j1201	797	16	and	and	CC
cord-022561-rv5j1201	797	17	subendothelial	subendothelial	JJ
cord-022561-rv5j1201	797	18	collagen	collagen	NN
cord-022561-rv5j1201	797	19	.	.	.
cord-022561-rv5j1201	798	1	Although	although	IN
cord-022561-rv5j1201	798	2	not	not	RB
cord-022561-rv5j1201	798	3	technically	technically	RB
cord-022561-rv5j1201	798	4	a	a	DT
cord-022561-rv5j1201	798	5	platelet	platelet	NN
cord-022561-rv5j1201	798	6	disorder	disorder	NN
cord-022561-rv5j1201	798	7	,	,	,
cord-022561-rv5j1201	798	8	von	von	NNP
cord-022561-rv5j1201	798	9	Willebrand	Willebrand	NNP
cord-022561-rv5j1201	798	10	disease	disease	NN
cord-022561-rv5j1201	798	11	is	be	VBZ
cord-022561-rv5j1201	798	12	often	often	RB
cord-022561-rv5j1201	798	13	classified	classify	VBN
cord-022561-rv5j1201	798	14	as	as	IN
cord-022561-rv5j1201	798	15	such	such	JJ
cord-022561-rv5j1201	798	16	because	because	IN
cord-022561-rv5j1201	798	17	it	-PRON-	PRP
cord-022561-rv5j1201	798	18	results	result	VBZ
cord-022561-rv5j1201	798	19	in	in	IN
cord-022561-rv5j1201	798	20	a	a	DT
cord-022561-rv5j1201	798	21	loss	loss	NN
cord-022561-rv5j1201	798	22	of	of	IN
cord-022561-rv5j1201	798	23	normal	normal	JJ
cord-022561-rv5j1201	798	24	platelet	platelet	NN
cord-022561-rv5j1201	798	25	function	function	NN
cord-022561-rv5j1201	798	26	.	.	.
cord-022561-rv5j1201	799	1	Different	different	JJ
cord-022561-rv5j1201	799	2	types	type	NNS
cord-022561-rv5j1201	799	3	of	of	IN
cord-022561-rv5j1201	799	4	von	von	NNP
cord-022561-rv5j1201	799	5	Willebrand	Willebrand	NNP
cord-022561-rv5j1201	799	6	disease	disease	NN
cord-022561-rv5j1201	799	7	vary	vary	VBP
cord-022561-rv5j1201	799	8	in	in	IN
cord-022561-rv5j1201	799	9	terms	term	NNS
cord-022561-rv5j1201	799	10	of	of	IN
cord-022561-rv5j1201	799	11	mode	mode	NN
cord-022561-rv5j1201	799	12	of	of	IN
cord-022561-rv5j1201	799	13	inheritance	inheritance	NN
cord-022561-rv5j1201	799	14	and	and	CC
cord-022561-rv5j1201	799	15	severity	severity	NN
cord-022561-rv5j1201	799	16	of	of	IN
cord-022561-rv5j1201	799	17	clinical	clinical	JJ
cord-022561-rv5j1201	799	18	disease	disease	NN
cord-022561-rv5j1201	799	19	.	.	.
cord-022561-rv5j1201	800	1	Type	type	NN
cord-022561-rv5j1201	800	2	I	-PRON-	PRP
cord-022561-rv5j1201	800	3	von	von	NNP
cord-022561-rv5j1201	800	4	Willebrand	Willebrand	NNP
cord-022561-rv5j1201	800	5	disease	disease	NN
cord-022561-rv5j1201	800	6	is	be	VBZ
cord-022561-rv5j1201	800	7	characterized	characterize	VBN
cord-022561-rv5j1201	800	8	by	by	IN
cord-022561-rv5j1201	800	9	low	low	JJ
cord-022561-rv5j1201	800	10	plasma	plasma	NN
cord-022561-rv5j1201	800	11	vWF	vwf	IN
cord-022561-rv5j1201	800	12	concentration	concentration	NN
cord-022561-rv5j1201	800	13	but	but	CC
cord-022561-rv5j1201	800	14	normal	normal	JJ
cord-022561-rv5j1201	800	15	multimeric	multimeric	JJ
cord-022561-rv5j1201	800	16	proportions	proportion	NNS
cord-022561-rv5j1201	800	17	and	and	CC
cord-022561-rv5j1201	800	18	a	a	DT
cord-022561-rv5j1201	800	19	mild	mild	JJ
cord-022561-rv5j1201	800	20	to	to	TO
cord-022561-rv5j1201	800	21	moderate	moderate	VB
cord-022561-rv5j1201	800	22	clinical	clinical	JJ
cord-022561-rv5j1201	800	23	bleeding	bleeding	NN
cord-022561-rv5j1201	800	24	tendency	tendency	NN
cord-022561-rv5j1201	800	25	;	;	:
cord-022561-rv5j1201	800	26	it	-PRON-	PRP
cord-022561-rv5j1201	800	27	has	have	VBZ
cord-022561-rv5j1201	800	28	been	be	VBN
cord-022561-rv5j1201	800	29	reported	report	VBN
cord-022561-rv5j1201	800	30	in	in	IN
cord-022561-rv5j1201	800	31	many	many	JJ
cord-022561-rv5j1201	800	32	dog	dog	NN
cord-022561-rv5j1201	800	33	breeds	breed	NNS
cord-022561-rv5j1201	800	34	.	.	.
cord-022561-rv5j1201	801	1	Type	Type	NNP
cord-022561-rv5j1201	801	2	II	II	NNP
cord-022561-rv5j1201	801	3	von	von	NNP
cord-022561-rv5j1201	801	4	Willebrand	Willebrand	NNP
cord-022561-rv5j1201	801	5	disease	disease	NN
cord-022561-rv5j1201	801	6	is	be	VBZ
cord-022561-rv5j1201	801	7	characterized	characterize	VBN
cord-022561-rv5j1201	801	8	by	by	IN
cord-022561-rv5j1201	801	9	low	low	JJ
cord-022561-rv5j1201	801	10	vWF	vwf	NN
cord-022561-rv5j1201	801	11	concentration	concentration	NN
cord-022561-rv5j1201	801	12	,	,	,
cord-022561-rv5j1201	801	13	absence	absence	NN
cord-022561-rv5j1201	801	14	of	of	IN
cord-022561-rv5j1201	801	15	large	large	JJ
cord-022561-rv5j1201	801	16	multimers	multimer	NNS
cord-022561-rv5j1201	801	17	,	,	,
cord-022561-rv5j1201	801	18	and	and	CC
cord-022561-rv5j1201	801	19	a	a	DT
cord-022561-rv5j1201	801	20	moderate	moderate	JJ
cord-022561-rv5j1201	801	21	to	to	IN
cord-022561-rv5j1201	801	22	severe	severe	JJ
cord-022561-rv5j1201	801	23	bleeding	bleeding	JJ
cord-022561-rv5j1201	801	24	tendency	tendency	NN
cord-022561-rv5j1201	801	25	;	;	:
cord-022561-rv5j1201	801	26	it	-PRON-	PRP
cord-022561-rv5j1201	801	27	has	have	VBZ
cord-022561-rv5j1201	801	28	been	be	VBN
cord-022561-rv5j1201	801	29	reported	report	VBN
cord-022561-rv5j1201	801	30	in	in	IN
cord-022561-rv5j1201	801	31	German	german	JJ
cord-022561-rv5j1201	801	32	short	short	JJ
cord-022561-rv5j1201	801	33	-	-	HYPH
cord-022561-rv5j1201	801	34	haired	haired	JJ
cord-022561-rv5j1201	801	35	pointer	pointer	NN
cord-022561-rv5j1201	801	36	and	and	CC
cord-022561-rv5j1201	801	37	German	german	JJ
cord-022561-rv5j1201	801	38	wirehaired	wirehaired	JJ
cord-022561-rv5j1201	801	39	pointer	pointer	NN
cord-022561-rv5j1201	801	40	dogs	dog	NNS
cord-022561-rv5j1201	801	41	.	.	.
cord-022561-rv5j1201	802	1	Type	type	NN
cord-022561-rv5j1201	802	2	III	III	NNP
cord-022561-rv5j1201	802	3	von	von	NNP
cord-022561-rv5j1201	802	4	Willebrand	Willebrand	NNP
cord-022561-rv5j1201	802	5	disease	disease	NN
cord-022561-rv5j1201	802	6	is	be	VBZ
cord-022561-rv5j1201	802	7	characterized	characterize	VBN
cord-022561-rv5j1201	802	8	by	by	IN
cord-022561-rv5j1201	802	9	absence	absence	NN
cord-022561-rv5j1201	802	10	of	of	IN
cord-022561-rv5j1201	802	11	vWF	vwf	NN
cord-022561-rv5j1201	802	12	and	and	CC
cord-022561-rv5j1201	802	13	a	a	DT
cord-022561-rv5j1201	802	14	severe	severe	JJ
cord-022561-rv5j1201	802	15	bleeding	bleeding	NN
cord-022561-rv5j1201	802	16	tendency	tendency	NN
cord-022561-rv5j1201	802	17	;	;	:
cord-022561-rv5j1201	802	18	familial	familial	JJ
cord-022561-rv5j1201	802	19	and	and	CC
cord-022561-rv5j1201	802	20	sporadic	sporadic	JJ
cord-022561-rv5j1201	802	21	cases	case	NNS
cord-022561-rv5j1201	802	22	have	have	VBP
cord-022561-rv5j1201	802	23	been	be	VBN
cord-022561-rv5j1201	802	24	reported	report	VBN
cord-022561-rv5j1201	802	25	in	in	IN
cord-022561-rv5j1201	802	26	numerous	numerous	JJ
cord-022561-rv5j1201	802	27	dog	dog	NN
cord-022561-rv5j1201	802	28	breeds	breed	NNS
cord-022561-rv5j1201	802	29	.	.	.
cord-022561-rv5j1201	803	1	The	the	DT
cord-022561-rv5j1201	803	2	buccal	buccal	JJ
cord-022561-rv5j1201	803	3	mucosal	mucosal	JJ
cord-022561-rv5j1201	803	4	bleeding	bleeding	NN
cord-022561-rv5j1201	803	5	time	time	NN
cord-022561-rv5j1201	803	6	is	be	VBZ
cord-022561-rv5j1201	803	7	prolonged	prolong	VBN
cord-022561-rv5j1201	803	8	with	with	IN
cord-022561-rv5j1201	803	9	von	von	NNP
cord-022561-rv5j1201	803	10	Willebrand	Willebrand	NNP
cord-022561-rv5j1201	803	11	disease	disease	NN
cord-022561-rv5j1201	803	12	,	,	,
cord-022561-rv5j1201	803	13	often	often	RB
cord-022561-rv5j1201	803	14	with	with	IN
cord-022561-rv5j1201	803	15	adequate	adequate	JJ
cord-022561-rv5j1201	803	16	concentrations	concentration	NNS
cord-022561-rv5j1201	803	17	of	of	IN
cord-022561-rv5j1201	803	18	platelets	platelet	NNS
cord-022561-rv5j1201	803	19	and	and	CC
cord-022561-rv5j1201	803	20	normal	normal	JJ
cord-022561-rv5j1201	803	21	prothrombin	prothrombin	NN
cord-022561-rv5j1201	803	22	time	time	NN
cord-022561-rv5j1201	803	23	and	and	CC
cord-022561-rv5j1201	803	24	partial	partial	JJ
cord-022561-rv5j1201	803	25	thromboplastin	thromboplastin	NNP
cord-022561-rv5j1201	803	26	time	time	NN
cord-022561-rv5j1201	803	27	(	(	-LRB-
cord-022561-rv5j1201	803	28	PTT	PTT	NNP
cord-022561-rv5j1201	803	29	)	)	-RRB-
cord-022561-rv5j1201	803	30	.	.	.
cord-022561-rv5j1201	804	1	However	however	RB
cord-022561-rv5j1201	804	2	,	,	,
cord-022561-rv5j1201	804	3	PTT	PTT	NNP
cord-022561-rv5j1201	804	4	may	may	MD
cord-022561-rv5j1201	804	5	be	be	VB
cord-022561-rv5j1201	804	6	mildly	mildly	RB
cord-022561-rv5j1201	804	7	prolonged	prolong	VBN
cord-022561-rv5j1201	804	8	because	because	IN
cord-022561-rv5j1201	804	9	vWF	vwf	NN
cord-022561-rv5j1201	804	10	stabilizes	stabilize	VBZ
cord-022561-rv5j1201	804	11	factor	factor	NN
cord-022561-rv5j1201	804	12	VIII	VIII	NNP
cord-022561-rv5j1201	804	13	,	,	,
cord-022561-rv5j1201	804	14	and	and	CC
cord-022561-rv5j1201	804	15	deficiency	deficiency	NN
cord-022561-rv5j1201	804	16	of	of	IN
cord-022561-rv5j1201	804	17	vWF	vwf	NN
cord-022561-rv5j1201	804	18	results	result	NNS
cord-022561-rv5j1201	804	19	in	in	IN
cord-022561-rv5j1201	804	20	enhanced	enhanced	JJ
cord-022561-rv5j1201	804	21	factor	factor	NN
cord-022561-rv5j1201	804	22	VIII	VIII	NNP
cord-022561-rv5j1201	804	23	degradation	degradation	NN
cord-022561-rv5j1201	804	24	.	.	.
cord-022561-rv5j1201	805	1	Grossly	grossly	RB
cord-022561-rv5j1201	805	2	,	,	,
cord-022561-rv5j1201	805	3	affected	affected	JJ
cord-022561-rv5j1201	805	4	animals	animal	NNS
cord-022561-rv5j1201	805	5	exhibit	exhibit	VBP
cord-022561-rv5j1201	805	6	bleeding	bleed	VBG
cord-022561-rv5j1201	805	7	tendencies	tendency	NNS
cord-022561-rv5j1201	805	8	,	,	,
cord-022561-rv5j1201	805	9	especially	especially	RB
cord-022561-rv5j1201	805	10	in	in	IN
cord-022561-rv5j1201	805	11	the	the	DT
cord-022561-rv5j1201	805	12	form	form	NN
cord-022561-rv5j1201	805	13	of	of	IN
cord-022561-rv5j1201	805	14	Inherited	inherit	VBN
cord-022561-rv5j1201	805	15	coagulation	coagulation	NN
cord-022561-rv5j1201	805	16	factor	factor	NN
cord-022561-rv5j1201	805	17	deficiencies	deficiency	NNS
cord-022561-rv5j1201	805	18	have	have	VBP
cord-022561-rv5j1201	805	19	been	be	VBN
cord-022561-rv5j1201	805	20	documented	document	VBN
cord-022561-rv5j1201	805	21	in	in	IN
cord-022561-rv5j1201	805	22	most	most	JJS
cord-022561-rv5j1201	805	23	domestic	domestic	JJ
cord-022561-rv5j1201	805	24	species	specie	NNS
cord-022561-rv5j1201	805	25	,	,	,
cord-022561-rv5j1201	805	26	including	include	VBG
cord-022561-rv5j1201	805	27	deficiencies	deficiency	NNS
cord-022561-rv5j1201	805	28	of	of	IN
cord-022561-rv5j1201	805	29	prekallikrein	prekallikrein	NNS
cord-022561-rv5j1201	805	30	and	and	CC
cord-022561-rv5j1201	805	31	factors	factor	NNS
cord-022561-rv5j1201	805	32	I	-PRON-	PRP
cord-022561-rv5j1201	805	33	,	,	,
cord-022561-rv5j1201	805	34	II	II	NNP
cord-022561-rv5j1201	805	35	,	,	,
cord-022561-rv5j1201	805	36	VII	VII	NNP
cord-022561-rv5j1201	805	37	,	,	,
cord-022561-rv5j1201	805	38	VIII	VIII	NNP
cord-022561-rv5j1201	805	39	,	,	,
cord-022561-rv5j1201	805	40	IX	IX	NNP
cord-022561-rv5j1201	805	41	,	,	,
cord-022561-rv5j1201	805	42	X	X	NNP
cord-022561-rv5j1201	805	43	,	,	,
cord-022561-rv5j1201	805	44	XI	XI	NNP
cord-022561-rv5j1201	805	45	,	,	,
cord-022561-rv5j1201	805	46	and	and	CC
cord-022561-rv5j1201	805	47	XII	XII	NNP
cord-022561-rv5j1201	805	48	.	.	.
cord-022561-rv5j1201	806	1	Of	of	IN
cord-022561-rv5j1201	806	2	these	these	DT
cord-022561-rv5j1201	806	3	disorders	disorder	NNS
cord-022561-rv5j1201	806	4	,	,	,
cord-022561-rv5j1201	806	5	hereditary	hereditary	JJ
cord-022561-rv5j1201	806	6	coagulation	coagulation	NN
cord-022561-rv5j1201	806	7	factor	factor	NN
cord-022561-rv5j1201	806	8	VIII	VIII	NNP
cord-022561-rv5j1201	806	9	(	(	-LRB-
cord-022561-rv5j1201	806	10	hemophilia	hemophilia	NN
cord-022561-rv5j1201	806	11	A	A	NNP
cord-022561-rv5j1201	806	12	)	)	-RRB-
cord-022561-rv5j1201	806	13	and	and	CC
cord-022561-rv5j1201	806	14	factor	factor	NN
cord-022561-rv5j1201	806	15	IX	IX	NNP
cord-022561-rv5j1201	806	16	(	(	-LRB-
cord-022561-rv5j1201	806	17	hemophilia	hemophilia	NN
cord-022561-rv5j1201	806	18	B	B	NNP
cord-022561-rv5j1201	806	19	)	)	-RRB-
cord-022561-rv5j1201	806	20	deficiencies	deficiency	NNS
cord-022561-rv5j1201	806	21	are	be	VBP
cord-022561-rv5j1201	806	22	most	most	RBS
cord-022561-rv5j1201	806	23	common	common	JJ
cord-022561-rv5j1201	806	24	.	.	.
cord-022561-rv5j1201	807	1	Hemophilia	Hemophilia	NNP
cord-022561-rv5j1201	807	2	A	A	NNP
cord-022561-rv5j1201	807	3	has	have	VBZ
cord-022561-rv5j1201	807	4	been	be	VBN
cord-022561-rv5j1201	807	5	recognized	recognize	VBN
cord-022561-rv5j1201	807	6	in	in	IN
cord-022561-rv5j1201	807	7	horses	horse	NNS
cord-022561-rv5j1201	807	8	,	,	,
cord-022561-rv5j1201	807	9	cattle	cattle	NNS
cord-022561-rv5j1201	807	10	,	,	,
cord-022561-rv5j1201	807	11	dogs	dog	NNS
cord-022561-rv5j1201	807	12	,	,	,
cord-022561-rv5j1201	807	13	and	and	CC
cord-022561-rv5j1201	807	14	cats	cat	NNS
cord-022561-rv5j1201	807	15	,	,	,
cord-022561-rv5j1201	807	16	and	and	CC
cord-022561-rv5j1201	807	17	hemophilia	hemophilia	NN
cord-022561-rv5j1201	807	18	B	b	NN
cord-022561-rv5j1201	807	19	occurs	occur	VBZ
cord-022561-rv5j1201	807	20	in	in	IN
cord-022561-rv5j1201	807	21	dogs	dog	NNS
cord-022561-rv5j1201	807	22	and	and	CC
cord-022561-rv5j1201	807	23	cats	cat	NNS
cord-022561-rv5j1201	807	24	.	.	.
cord-022561-rv5j1201	808	1	Both	both	DT
cord-022561-rv5j1201	808	2	disorders	disorder	NNS
cord-022561-rv5j1201	808	3	have	have	VBP
cord-022561-rv5j1201	808	4	an	an	DT
cord-022561-rv5j1201	808	5	X	x	NN
cord-022561-rv5j1201	808	6	-	-	HYPH
cord-022561-rv5j1201	808	7	linked	link	VBN
cord-022561-rv5j1201	808	8	recessive	recessive	JJ
cord-022561-rv5j1201	808	9	mode	mode	NN
cord-022561-rv5j1201	808	10	of	of	IN
cord-022561-rv5j1201	808	11	inheritance	inheritance	NN
cord-022561-rv5j1201	808	12	,	,	,
cord-022561-rv5j1201	808	13	meaning	mean	VBG
cord-022561-rv5j1201	808	14	that	that	IN
cord-022561-rv5j1201	808	15	clinical	clinical	JJ
cord-022561-rv5j1201	808	16	disease	disease	NN
cord-022561-rv5j1201	808	17	is	be	VBZ
cord-022561-rv5j1201	808	18	more	more	RBR
cord-022561-rv5j1201	808	19	common	common	JJ
cord-022561-rv5j1201	808	20	in	in	IN
cord-022561-rv5j1201	808	21	males	male	NNS
cord-022561-rv5j1201	808	22	.	.	.
cord-022561-rv5j1201	809	1	Affected	affected	JJ
cord-022561-rv5j1201	809	2	males	male	NNS
cord-022561-rv5j1201	809	3	have	have	VBP
cord-022561-rv5j1201	809	4	variable	variable	JJ
cord-022561-rv5j1201	809	5	tendencies	tendency	NNS
cord-022561-rv5j1201	809	6	to	to	TO
cord-022561-rv5j1201	809	7	bleed	bleed	VB
cord-022561-rv5j1201	809	8	,	,	,
cord-022561-rv5j1201	809	9	depending	depend	VBG
cord-022561-rv5j1201	809	10	on	on	IN
cord-022561-rv5j1201	809	11	the	the	DT
cord-022561-rv5j1201	809	12	severity	severity	NN
cord-022561-rv5j1201	809	13	of	of	IN
cord-022561-rv5j1201	809	14	the	the	DT
cord-022561-rv5j1201	809	15	deficiency	deficiency	NN
cord-022561-rv5j1201	809	16	,	,	,
cord-022561-rv5j1201	809	17	exposure	exposure	NN
cord-022561-rv5j1201	809	18	to	to	IN
cord-022561-rv5j1201	809	19	trauma	trauma	NN
cord-022561-rv5j1201	809	20	,	,	,
cord-022561-rv5j1201	809	21	and	and	CC
cord-022561-rv5j1201	809	22	size	size	NN
cord-022561-rv5j1201	809	23	and	and	CC
cord-022561-rv5j1201	809	24	activity	activity	NN
cord-022561-rv5j1201	809	25	level	level	NN
cord-022561-rv5j1201	809	26	of	of	IN
cord-022561-rv5j1201	809	27	the	the	DT
cord-022561-rv5j1201	809	28	affected	affect	VBN
cord-022561-rv5j1201	809	29	individual	individual	NN
cord-022561-rv5j1201	809	30	.	.	.
cord-022561-rv5j1201	810	1	Carrier	carrier	NN
cord-022561-rv5j1201	810	2	females	female	NNS
cord-022561-rv5j1201	810	3	are	be	VBP
cord-022561-rv5j1201	810	4	usually	usually	RB
cord-022561-rv5j1201	810	5	asymptomatic	asymptomatic	JJ
cord-022561-rv5j1201	810	6	.	.	.
cord-022561-rv5j1201	811	1	Laboratory	laboratory	NN
cord-022561-rv5j1201	811	2	tests	test	NNS
cord-022561-rv5j1201	811	3	often	often	RB
cord-022561-rv5j1201	811	4	reveal	reveal	VBP
cord-022561-rv5j1201	811	5	adequate	adequate	JJ
cord-022561-rv5j1201	811	6	platelets	platelet	NNS
cord-022561-rv5j1201	811	7	,	,	,
cord-022561-rv5j1201	811	8	normal	normal	JJ
cord-022561-rv5j1201	811	9	prothrombin	prothrombin	NN
cord-022561-rv5j1201	811	10	times	time	NNS
cord-022561-rv5j1201	811	11	,	,	,
cord-022561-rv5j1201	811	12	and	and	CC
cord-022561-rv5j1201	811	13	prolonged	prolong	VBD
cord-022561-rv5j1201	811	14	partial	partial	JJ
cord-022561-rv5j1201	811	15	thromboplastin	thromboplastin	NNS
cord-022561-rv5j1201	811	16	times	time	NNS
cord-022561-rv5j1201	811	17	.	.	.
cord-022561-rv5j1201	812	1	Hereditary	hereditary	JJ
cord-022561-rv5j1201	812	2	defects	defect	NNS
cord-022561-rv5j1201	812	3	in	in	IN
cord-022561-rv5j1201	812	4	γ	γ	NN
cord-022561-rv5j1201	812	5	-	-	HYPH
cord-022561-rv5j1201	812	6	glutamyl	glutamyl	NNP
cord-022561-rv5j1201	812	7	carboxylase	carboxylase	NNP
cord-022561-rv5j1201	812	8	,	,	,
cord-022561-rv5j1201	812	9	the	the	DT
cord-022561-rv5j1201	812	10	enzyme	enzyme	NN
cord-022561-rv5j1201	812	11	required	require	VBN
cord-022561-rv5j1201	812	12	for	for	IN
cord-022561-rv5j1201	812	13	normal	normal	JJ
cord-022561-rv5j1201	812	14	carboxylation	carboxylation	NN
cord-022561-rv5j1201	812	15	of	of	IN
cord-022561-rv5j1201	812	16	vitamin	vitamin	NN
cord-022561-rv5j1201	812	17	K	k	NN
cord-022561-rv5j1201	812	18	-	-	HYPH
cord-022561-rv5j1201	812	19	dependent	dependent	JJ
cord-022561-rv5j1201	812	20	coagulation	coagulation	NN
cord-022561-rv5j1201	812	21	factors	factor	NNS
cord-022561-rv5j1201	812	22	,	,	,
cord-022561-rv5j1201	812	23	have	have	VBP
cord-022561-rv5j1201	812	24	been	be	VBN
cord-022561-rv5j1201	812	25	recognized	recognize	VBN
cord-022561-rv5j1201	812	26	in	in	IN
cord-022561-rv5j1201	812	27	a	a	DT
cord-022561-rv5j1201	812	28	flock	flock	NN
cord-022561-rv5j1201	812	29	of	of	IN
cord-022561-rv5j1201	812	30	Rambouillet	Rambouillet	NNP
cord-022561-rv5j1201	812	31	sheep	sheep	NN
cord-022561-rv5j1201	812	32	and	and	CC
cord-022561-rv5j1201	812	33	two	two	CD
cord-022561-rv5j1201	812	34	Devon	Devon	NNP
cord-022561-rv5j1201	812	35	rex	rex	NNP
cord-022561-rv5j1201	812	36	cats	cat	NNS
cord-022561-rv5j1201	812	37	from	from	IN
cord-022561-rv5j1201	812	38	the	the	DT
cord-022561-rv5j1201	812	39	same	same	JJ
cord-022561-rv5j1201	812	40	litter	litter	NN
cord-022561-rv5j1201	812	41	.	.	.
cord-022561-rv5j1201	813	1	The	the	DT
cord-022561-rv5j1201	813	2	genetic	genetic	JJ
cord-022561-rv5j1201	813	3	defect	defect	NN
cord-022561-rv5j1201	813	4	is	be	VBZ
cord-022561-rv5j1201	813	5	not	not	RB
cord-022561-rv5j1201	813	6	known	know	VBN
cord-022561-rv5j1201	813	7	in	in	IN
cord-022561-rv5j1201	813	8	cats	cat	NNS
cord-022561-rv5j1201	813	9	,	,	,
cord-022561-rv5j1201	813	10	but	but	CC
cord-022561-rv5j1201	813	11	in	in	IN
cord-022561-rv5j1201	813	12	sheep	sheep	NN
cord-022561-rv5j1201	813	13	it	-PRON-	PRP
cord-022561-rv5j1201	813	14	is	be	VBZ
cord-022561-rv5j1201	813	15	an	an	DT
cord-022561-rv5j1201	813	16	autosomal	autosomal	JJ
cord-022561-rv5j1201	813	17	recessive	recessive	JJ
cord-022561-rv5j1201	813	18	trait	trait	NN
cord-022561-rv5j1201	813	19	that	that	WDT
cord-022561-rv5j1201	813	20	results	result	VBZ
cord-022561-rv5j1201	813	21	in	in	IN
cord-022561-rv5j1201	813	22	a	a	DT
cord-022561-rv5j1201	813	23	premature	premature	JJ
cord-022561-rv5j1201	813	24	stop	stop	NN
cord-022561-rv5j1201	813	25	codon	codon	NN
cord-022561-rv5j1201	813	26	and	and	CC
cord-022561-rv5j1201	813	27	truncated	truncated	JJ
cord-022561-rv5j1201	813	28	γ	γ	NN
cord-022561-rv5j1201	813	29	-	-	HYPH
cord-022561-rv5j1201	813	30	glutamyl	glutamyl	NNP
cord-022561-rv5j1201	813	31	carboxylase	carboxylase	NN
cord-022561-rv5j1201	813	32	.	.	.
cord-022561-rv5j1201	814	1	In	in	IN
cord-022561-rv5j1201	814	2	sheep	sheep	NN
cord-022561-rv5j1201	814	3	there	there	EX
cord-022561-rv5j1201	814	4	is	be	VBZ
cord-022561-rv5j1201	814	5	increased	increase	VBN
cord-022561-rv5j1201	814	6	lamb	lamb	NN
cord-022561-rv5j1201	814	7	mortality	mortality	NN
cord-022561-rv5j1201	814	8	with	with	IN
cord-022561-rv5j1201	814	9	excessive	excessive	JJ
cord-022561-rv5j1201	814	10	bleeding	bleeding	NN
cord-022561-rv5j1201	814	11	during	during	IN
cord-022561-rv5j1201	814	12	parturition	parturition	NN
cord-022561-rv5j1201	814	13	,	,	,
cord-022561-rv5j1201	814	14	especially	especially	RB
cord-022561-rv5j1201	814	15	through	through	IN
cord-022561-rv5j1201	814	16	the	the	DT
cord-022561-rv5j1201	814	17	umbilicus	umbilicus	NN
cord-022561-rv5j1201	814	18	or	or	CC
cord-022561-rv5j1201	814	19	into	into	IN
cord-022561-rv5j1201	814	20	subcutaneous	subcutaneous	JJ
cord-022561-rv5j1201	814	21	tissues	tissue	NNS
cord-022561-rv5j1201	814	22	.	.	.
cord-022561-rv5j1201	815	1	gingival	gingival	JJ
cord-022561-rv5j1201	815	2	bleeding	bleeding	NN
cord-022561-rv5j1201	815	3	,	,	,
cord-022561-rv5j1201	815	4	epistaxis	epistaxis	NN
cord-022561-rv5j1201	815	5	,	,	,
cord-022561-rv5j1201	815	6	and	and	CC
cord-022561-rv5j1201	815	7	hematuria	hematuria	NN
cord-022561-rv5j1201	815	8	or	or	CC
cord-022561-rv5j1201	815	9	at	at	IN
cord-022561-rv5j1201	815	10	sites	site	NNS
cord-022561-rv5j1201	815	11	of	of	IN
cord-022561-rv5j1201	815	12	injections	injection	NNS
cord-022561-rv5j1201	815	13	,	,	,
cord-022561-rv5j1201	815	14	venipuncture	venipuncture	NN
cord-022561-rv5j1201	815	15	,	,	,
cord-022561-rv5j1201	815	16	or	or	CC
cord-022561-rv5j1201	815	17	surgery	surgery	NN
cord-022561-rv5j1201	815	18	.	.	.
cord-022561-rv5j1201	816	1	of	of	IN
cord-022561-rv5j1201	816	2	loss	loss	NN
cord-022561-rv5j1201	816	3	is	be	VBZ
cord-022561-rv5j1201	816	4	through	through	IN
cord-022561-rv5j1201	816	5	the	the	DT
cord-022561-rv5j1201	816	6	gastrointestinal	gastrointestinal	JJ
cord-022561-rv5j1201	816	7	tract	tract	NN
cord-022561-rv5j1201	816	8	(	(	-LRB-
cord-022561-rv5j1201	816	9	e.g.	e.g.	RB
cord-022561-rv5j1201	816	10	,	,	,
cord-022561-rv5j1201	816	11	neoplasia	neoplasia	NN
cord-022561-rv5j1201	816	12	in	in	IN
cord-022561-rv5j1201	816	13	older	old	JJR
cord-022561-rv5j1201	816	14	animals	animal	NNS
cord-022561-rv5j1201	816	15	or	or	CC
cord-022561-rv5j1201	816	16	hookworm	hookworm	NN
cord-022561-rv5j1201	816	17	infection	infection	NN
cord-022561-rv5j1201	816	18	in	in	IN
cord-022561-rv5j1201	816	19	puppies	puppy	NNS
cord-022561-rv5j1201	816	20	)	)	-RRB-
cord-022561-rv5j1201	816	21	.	.	.
cord-022561-rv5j1201	817	1	Chronic	chronic	JJ
cord-022561-rv5j1201	817	2	blood	blood	NN
cord-022561-rv5j1201	817	3	loss	loss	NN
cord-022561-rv5j1201	817	4	may	may	MD
cord-022561-rv5j1201	817	5	also	also	RB
cord-022561-rv5j1201	817	6	be	be	VB
cord-022561-rv5j1201	817	7	caused	cause	VBN
cord-022561-rv5j1201	817	8	by	by	IN
cord-022561-rv5j1201	817	9	marked	mark	VBN
cord-022561-rv5j1201	817	10	ectoparasitism	ectoparasitism	NN
cord-022561-rv5j1201	817	11	(	(	-LRB-
cord-022561-rv5j1201	817	12	e.g.	e.g.	RB
cord-022561-rv5j1201	817	13	,	,	,
cord-022561-rv5j1201	817	14	pediculosis	pediculosis	NN
cord-022561-rv5j1201	817	15	in	in	IN
cord-022561-rv5j1201	817	16	cattle	cattle	NNS
cord-022561-rv5j1201	817	17	or	or	CC
cord-022561-rv5j1201	817	18	massive	massive	JJ
cord-022561-rv5j1201	817	19	flea	flea	NN
cord-022561-rv5j1201	817	20	burden	burden	NN
cord-022561-rv5j1201	817	21	in	in	IN
cord-022561-rv5j1201	817	22	kittens	kitten	NNS
cord-022561-rv5j1201	817	23	and	and	CC
cord-022561-rv5j1201	817	24	puppies	puppy	NNS
cord-022561-rv5j1201	817	25	)	)	-RRB-
cord-022561-rv5j1201	817	26	,	,	,
cord-022561-rv5j1201	817	27	neoplasia	neoplasia	NN
cord-022561-rv5j1201	817	28	in	in	IN
cord-022561-rv5j1201	817	29	locations	location	NNS
cord-022561-rv5j1201	817	30	other	other	JJ
cord-022561-rv5j1201	817	31	than	than	IN
cord-022561-rv5j1201	817	32	the	the	DT
cord-022561-rv5j1201	817	33	gastrointestinal	gastrointestinal	JJ
cord-022561-rv5j1201	817	34	tract	tract	NN
cord-022561-rv5j1201	817	35	(	(	-LRB-
cord-022561-rv5j1201	817	36	e.g.	e.g.	RB
cord-022561-rv5j1201	817	37	,	,	,
cord-022561-rv5j1201	817	38	cutaneous	cutaneous	JJ
cord-022561-rv5j1201	817	39	hemangiosarcoma	hemangiosarcoma	NN
cord-022561-rv5j1201	817	40	)	)	-RRB-
cord-022561-rv5j1201	817	41	,	,	,
cord-022561-rv5j1201	817	42	coagulation	coagulation	NN
cord-022561-rv5j1201	817	43	disorders	disorder	NNS
cord-022561-rv5j1201	817	44	,	,	,
cord-022561-rv5j1201	817	45	and	and	CC
cord-022561-rv5j1201	817	46	repeated	repeat	VBD
cord-022561-rv5j1201	817	47	phlebotomy	phlebotomy	NN
cord-022561-rv5j1201	817	48	of	of	IN
cord-022561-rv5j1201	817	49	blood	blood	NN
cord-022561-rv5j1201	817	50	donor	donor	NN
cord-022561-rv5j1201	817	51	animals	animal	NNS
cord-022561-rv5j1201	817	52	.	.	.
cord-022561-rv5j1201	818	1	Rapidly	rapidly	RB
cord-022561-rv5j1201	818	2	growing	grow	VBG
cord-022561-rv5j1201	818	3	nursing	nursing	NN
cord-022561-rv5j1201	818	4	animals	animal	NNS
cord-022561-rv5j1201	818	5	may	may	MD
cord-022561-rv5j1201	818	6	be	be	VB
cord-022561-rv5j1201	818	7	iron	iron	NN
cord-022561-rv5j1201	818	8	deficient	deficient	JJ
cord-022561-rv5j1201	818	9	when	when	WRB
cord-022561-rv5j1201	818	10	compared	compare	VBN
cord-022561-rv5j1201	818	11	with	with	IN
cord-022561-rv5j1201	818	12	adults	adult	NNS
cord-022561-rv5j1201	818	13	because	because	IN
cord-022561-rv5j1201	818	14	milk	milk	NN
cord-022561-rv5j1201	818	15	is	be	VBZ
cord-022561-rv5j1201	818	16	an	an	DT
cord-022561-rv5j1201	818	17	iron	iron	NN
cord-022561-rv5j1201	818	18	-	-	HYPH
cord-022561-rv5j1201	818	19	poor	poor	JJ
cord-022561-rv5j1201	818	20	diet	diet	NN
cord-022561-rv5j1201	818	21	.	.	.
cord-022561-rv5j1201	819	1	In	in	IN
cord-022561-rv5j1201	819	2	most	most	JJS
cord-022561-rv5j1201	819	3	cases	case	NNS
cord-022561-rv5j1201	819	4	this	this	DT
cord-022561-rv5j1201	819	5	has	have	VBZ
cord-022561-rv5j1201	819	6	little	little	JJ
cord-022561-rv5j1201	819	7	clinical	clinical	JJ
cord-022561-rv5j1201	819	8	significance	significance	NN
cord-022561-rv5j1201	819	9	(	(	-LRB-
cord-022561-rv5j1201	819	10	and	and	CC
cord-022561-rv5j1201	819	11	in	in	IN
cord-022561-rv5j1201	819	12	fact	fact	NN
cord-022561-rv5j1201	819	13	is	be	VBZ
cord-022561-rv5j1201	819	14	normal	normal	JJ
cord-022561-rv5j1201	819	15	)	)	-RRB-
cord-022561-rv5j1201	819	16	.	.	.
cord-022561-rv5j1201	820	1	An	an	DT
cord-022561-rv5j1201	820	2	important	important	JJ
cord-022561-rv5j1201	820	3	exception	exception	NN
cord-022561-rv5j1201	820	4	is	be	VBZ
cord-022561-rv5j1201	820	5	piglets	piglet	NNS
cord-022561-rv5j1201	820	6	with	with	IN
cord-022561-rv5j1201	820	7	no	no	DT
cord-022561-rv5j1201	820	8	access	access	NN
cord-022561-rv5j1201	820	9	to	to	IN
cord-022561-rv5j1201	820	10	iron	iron	NN
cord-022561-rv5j1201	820	11	,	,	,
cord-022561-rv5j1201	820	12	which	which	WDT
cord-022561-rv5j1201	820	13	may	may	MD
cord-022561-rv5j1201	820	14	cause	cause	VB
cord-022561-rv5j1201	820	15	anemia	anemia	NN
cord-022561-rv5j1201	820	16	,	,	,
cord-022561-rv5j1201	820	17	failure	failure	NN
cord-022561-rv5j1201	820	18	to	to	TO
cord-022561-rv5j1201	820	19	thrive	thrive	VB
cord-022561-rv5j1201	820	20	,	,	,
cord-022561-rv5j1201	820	21	and	and	CC
cord-022561-rv5j1201	820	22	increased	increase	VBN
cord-022561-rv5j1201	820	23	mortality	mortality	NN
cord-022561-rv5j1201	820	24	.	.	.
cord-022561-rv5j1201	821	1	Neonatal	neonatal	JJ
cord-022561-rv5j1201	821	2	piglets	piglet	NNS
cord-022561-rv5j1201	821	3	are	be	VBP
cord-022561-rv5j1201	821	4	routinely	routinely	RB
cord-022561-rv5j1201	821	5	given	give	VBN
cord-022561-rv5j1201	821	6	parenteral	parenteral	JJ
cord-022561-rv5j1201	821	7	iron	iron	NN
cord-022561-rv5j1201	821	8	for	for	IN
cord-022561-rv5j1201	821	9	this	this	DT
cord-022561-rv5j1201	821	10	reason	reason	NN
cord-022561-rv5j1201	821	11	.	.	.
cord-022561-rv5j1201	822	1	Copper	copper	NN
cord-022561-rv5j1201	822	2	deficiency	deficiency	NN
cord-022561-rv5j1201	822	3	can	can	MD
cord-022561-rv5j1201	822	4	cause	cause	VB
cord-022561-rv5j1201	822	5	iron	iron	NN
cord-022561-rv5j1201	822	6	deficiency	deficiency	NN
cord-022561-rv5j1201	822	7	in	in	IN
cord-022561-rv5j1201	822	8	ruminants	ruminant	NNS
cord-022561-rv5j1201	822	9	and	and	CC
cord-022561-rv5j1201	822	10	may	may	MD
cord-022561-rv5j1201	822	11	occur	occur	VB
cord-022561-rv5j1201	822	12	because	because	IN
cord-022561-rv5j1201	822	13	of	of	IN
cord-022561-rv5j1201	822	14	copper	copper	NN
cord-022561-rv5j1201	822	15	-	-	HYPH
cord-022561-rv5j1201	822	16	deficient	deficient	JJ
cord-022561-rv5j1201	822	17	forage	forage	NN
cord-022561-rv5j1201	822	18	or	or	CC
cord-022561-rv5j1201	822	19	impaired	impaired	JJ
cord-022561-rv5j1201	822	20	usage	usage	NN
cord-022561-rv5j1201	822	21	of	of	IN
cord-022561-rv5j1201	822	22	copper	copper	NN
cord-022561-rv5j1201	822	23	by	by	IN
cord-022561-rv5j1201	822	24	high	high	JJ
cord-022561-rv5j1201	822	25	dietary	dietary	JJ
cord-022561-rv5j1201	822	26	molybdenum	molybdenum	NN
cord-022561-rv5j1201	822	27	or	or	CC
cord-022561-rv5j1201	822	28	sulfate	sulfate	NN
cord-022561-rv5j1201	822	29	.	.	.
cord-022561-rv5j1201	823	1	It	-PRON-	PRP
cord-022561-rv5j1201	823	2	is	be	VBZ
cord-022561-rv5j1201	823	3	believed	believe	VBN
cord-022561-rv5j1201	823	4	that	that	IN
cord-022561-rv5j1201	823	5	copper	copper	NN
cord-022561-rv5j1201	823	6	deficiency	deficiency	NN
cord-022561-rv5j1201	823	7	impairs	impair	VBZ
cord-022561-rv5j1201	823	8	production	production	NN
cord-022561-rv5j1201	823	9	of	of	IN
cord-022561-rv5j1201	823	10	ceruloplasmin	ceruloplasmin	NNP
cord-022561-rv5j1201	823	11	,	,	,
cord-022561-rv5j1201	823	12	a	a	DT
cord-022561-rv5j1201	823	13	copper	copper	NN
cord-022561-rv5j1201	823	14	-	-	HYPH
cord-022561-rv5j1201	823	15	containing	contain	VBG
cord-022561-rv5j1201	823	16	enzyme	enzyme	NN
cord-022561-rv5j1201	823	17	involved	involve	VBN
cord-022561-rv5j1201	823	18	in	in	IN
cord-022561-rv5j1201	823	19	gastrointestinal	gastrointestinal	JJ
cord-022561-rv5j1201	823	20	iron	iron	NN
cord-022561-rv5j1201	823	21	absorption	absorption	NN
cord-022561-rv5j1201	823	22	.	.	.
cord-022561-rv5j1201	824	1	Iron	iron	NN
cord-022561-rv5j1201	824	2	deficiency	deficiency	NN
cord-022561-rv5j1201	824	3	causes	cause	VBZ
cord-022561-rv5j1201	824	4	anemia	anemia	NN
cord-022561-rv5j1201	824	5	by	by	IN
cord-022561-rv5j1201	824	6	impaired	impaired	JJ
cord-022561-rv5j1201	824	7	hemoglobin	hemoglobin	NN
cord-022561-rv5j1201	824	8	synthesis	synthesis	NN
cord-022561-rv5j1201	824	9	.	.	.
cord-022561-rv5j1201	825	1	Iron	iron	NN
cord-022561-rv5j1201	825	2	is	be	VBZ
cord-022561-rv5j1201	825	3	an	an	DT
cord-022561-rv5j1201	825	4	essential	essential	JJ
cord-022561-rv5j1201	825	5	component	component	NN
cord-022561-rv5j1201	825	6	of	of	IN
cord-022561-rv5j1201	825	7	hemoglobin	hemoglobin	NN
cord-022561-rv5j1201	825	8	,	,	,
cord-022561-rv5j1201	825	9	and	and	CC
cord-022561-rv5j1201	825	10	when	when	WRB
cord-022561-rv5j1201	825	11	it	-PRON-	PRP
cord-022561-rv5j1201	825	12	is	be	VBZ
cord-022561-rv5j1201	825	13	absent	absent	JJ
cord-022561-rv5j1201	825	14	,	,	,
cord-022561-rv5j1201	825	15	hemoglobin	hemoglobin	NN
cord-022561-rv5j1201	825	16	synthesis	synthesis	NN
cord-022561-rv5j1201	825	17	is	be	VBZ
cord-022561-rv5j1201	825	18	depressed	depressed	JJ
cord-022561-rv5j1201	825	19	.	.	.
cord-022561-rv5j1201	826	1	Because	because	IN
cord-022561-rv5j1201	826	2	erythrocyte	erythrocyte	NN
cord-022561-rv5j1201	826	3	maturation	maturation	NN
cord-022561-rv5j1201	826	4	is	be	VBZ
cord-022561-rv5j1201	826	5	dependent	dependent	JJ
cord-022561-rv5j1201	826	6	upon	upon	IN
cord-022561-rv5j1201	826	7	obtaining	obtain	VBG
cord-022561-rv5j1201	826	8	a	a	DT
cord-022561-rv5j1201	826	9	critical	critical	JJ
cord-022561-rv5j1201	826	10	hemoglobin	hemoglobin	NN
cord-022561-rv5j1201	826	11	concentration	concentration	NN
cord-022561-rv5j1201	826	12	,	,	,
cord-022561-rv5j1201	826	13	maturing	mature	VBG
cord-022561-rv5j1201	826	14	erythroid	erythroid	NN
cord-022561-rv5j1201	826	15	precursors	precursor	NNS
cord-022561-rv5j1201	826	16	undergo	undergo	VBP
cord-022561-rv5j1201	826	17	additional	additional	JJ
cord-022561-rv5j1201	826	18	cell	cell	NN
cord-022561-rv5j1201	826	19	divisions	division	NNS
cord-022561-rv5j1201	826	20	during	during	IN
cord-022561-rv5j1201	826	21	iron	iron	NN
cord-022561-rv5j1201	826	22	-	-	HYPH
cord-022561-rv5j1201	826	23	deficient	deficient	JJ
cord-022561-rv5j1201	826	24	states	state	NNS
cord-022561-rv5j1201	826	25	.	.	.
cord-022561-rv5j1201	827	1	These	these	DT
cord-022561-rv5j1201	827	2	additional	additional	JJ
cord-022561-rv5j1201	827	3	cell	cell	NN
cord-022561-rv5j1201	827	4	divisions	division	NNS
cord-022561-rv5j1201	827	5	result	result	VBP
cord-022561-rv5j1201	827	6	in	in	IN
cord-022561-rv5j1201	827	7	small	small	JJ
cord-022561-rv5j1201	827	8	erythrocytes	erythrocyte	NNS
cord-022561-rv5j1201	827	9	,	,	,
cord-022561-rv5j1201	827	10	termed	term	VBN
cord-022561-rv5j1201	827	11	microcytes	microcyte	NNS
cord-022561-rv5j1201	827	12	(	(	-LRB-
cord-022561-rv5j1201	827	13	see	see	VB
cord-022561-rv5j1201	827	14	Fig	Fig	NNP
cord-022561-rv5j1201	827	15	.	.	.
cord-022561-rv5j1201	828	1	13	13	CD
cord-022561-rv5j1201	828	2	-15	-15	CD
cord-022561-rv5j1201	828	3	,	,	,
cord-022561-rv5j1201	828	4	G	G	NNP
cord-022561-rv5j1201	828	5	)	)	-RRB-
cord-022561-rv5j1201	828	6	.	.	.
cord-022561-rv5j1201	829	1	However	however	RB
cord-022561-rv5j1201	829	2	,	,	,
cord-022561-rv5j1201	829	3	erythrocytes	erythrocyte	VBZ
cord-022561-rv5j1201	829	4	with	with	IN
cord-022561-rv5j1201	829	5	low	low	JJ
cord-022561-rv5j1201	829	6	hemoglobin	hemoglobin	NN
cord-022561-rv5j1201	829	7	concentrations	concentration	NNS
cord-022561-rv5j1201	829	8	are	be	VBP
cord-022561-rv5j1201	829	9	produced	produce	VBN
cord-022561-rv5j1201	829	10	when	when	WRB
cord-022561-rv5j1201	829	11	microcyte	microcyte	NNP
cord-022561-rv5j1201	829	12	formation	formation	NN
cord-022561-rv5j1201	829	13	can	can	MD
cord-022561-rv5j1201	829	14	no	no	RB
cord-022561-rv5j1201	829	15	longer	longer	RB
cord-022561-rv5j1201	829	16	compensate	compensate	VB
cord-022561-rv5j1201	829	17	for	for	IN
cord-022561-rv5j1201	829	18	iron	iron	NN
cord-022561-rv5j1201	829	19	deficiency	deficiency	NN
cord-022561-rv5j1201	829	20	.	.	.
cord-022561-rv5j1201	830	1	The	the	DT
cord-022561-rv5j1201	830	2	classic	classic	JJ
cord-022561-rv5j1201	830	3	hematologic	hematologic	JJ
cord-022561-rv5j1201	830	4	picture	picture	NN
cord-022561-rv5j1201	830	5	with	with	IN
cord-022561-rv5j1201	830	6	iron	iron	NN
cord-022561-rv5j1201	830	7	deficiency	deficiency	NN
cord-022561-rv5j1201	830	8	anemia	anemia	NN
cord-022561-rv5j1201	830	9	is	be	VBZ
cord-022561-rv5j1201	830	10	microcytic	microcytic	JJ
cord-022561-rv5j1201	830	11	(	(	-LRB-
cord-022561-rv5j1201	830	12	i.e.	i.e.	FW
cord-022561-rv5j1201	830	13	,	,	,
cord-022561-rv5j1201	830	14	decreased	decrease	VBD
cord-022561-rv5j1201	830	15	MCV	MCV	NNP
cord-022561-rv5j1201	830	16	)	)	-RRB-
cord-022561-rv5j1201	830	17	,	,	,
cord-022561-rv5j1201	830	18	hypochromic	hypochromic	JJ
cord-022561-rv5j1201	830	19	(	(	-LRB-
cord-022561-rv5j1201	830	20	i.e.	i.e.	FW
cord-022561-rv5j1201	830	21	,	,	,
cord-022561-rv5j1201	830	22	decreased	decrease	VBD
cord-022561-rv5j1201	830	23	MCHC	MCHC	NNP
cord-022561-rv5j1201	830	24	)	)	-RRB-
cord-022561-rv5j1201	830	25	anemia	anemia	NN
cord-022561-rv5j1201	830	26	.	.	.
cord-022561-rv5j1201	831	1	Microcytes	Microcytes	NNP
cord-022561-rv5j1201	831	2	and	and	CC
cord-022561-rv5j1201	831	3	hypochromasia	hypochromasia	NNP
cord-022561-rv5j1201	831	4	(	(	-LRB-
cord-022561-rv5j1201	831	5	see	see	VB
cord-022561-rv5j1201	831	6	Fig	Fig	NNP
cord-022561-rv5j1201	831	7	.	.	.
cord-022561-rv5j1201	832	1	13	13	CD
cord-022561-rv5j1201	832	2	-15	-15	CD
cord-022561-rv5j1201	832	3	,	,	,
cord-022561-rv5j1201	832	4	G	G	NNP
cord-022561-rv5j1201	832	5	)	)	-RRB-
cord-022561-rv5j1201	832	6	may	may	MD
cord-022561-rv5j1201	832	7	also	also	RB
cord-022561-rv5j1201	832	8	be	be	VB
cord-022561-rv5j1201	832	9	discernible	discernible	JJ
cord-022561-rv5j1201	832	10	on	on	IN
cord-022561-rv5j1201	832	11	blood	blood	NN
cord-022561-rv5j1201	832	12	smear	smear	NN
cord-022561-rv5j1201	832	13	examination	examination	NN
cord-022561-rv5j1201	832	14	as	as	IN
cord-022561-rv5j1201	832	15	erythrocytes	erythrocyte	NNS
cord-022561-rv5j1201	832	16	that	that	WDT
cord-022561-rv5j1201	832	17	are	be	VBP
cord-022561-rv5j1201	832	18	abnormally	abnormally	RB
cord-022561-rv5j1201	832	19	small	small	JJ
cord-022561-rv5j1201	832	20	and	and	CC
cord-022561-rv5j1201	832	21	paler	pale	JJR
cord-022561-rv5j1201	832	22	-	-	HYPH
cord-022561-rv5j1201	832	23	staining	stain	VBG
cord-022561-rv5j1201	832	24	,	,	,
cord-022561-rv5j1201	832	25	respectively	respectively	RB
cord-022561-rv5j1201	832	26	.	.	.
cord-022561-rv5j1201	833	1	Early	early	JJ
cord-022561-rv5j1201	833	2	iron	iron	NN
cord-022561-rv5j1201	833	3	deficiency	deficiency	NN
cord-022561-rv5j1201	833	4	anemia	anemia	NN
cord-022561-rv5j1201	833	5	is	be	VBZ
cord-022561-rv5j1201	833	6	poorly	poorly	RB
cord-022561-rv5j1201	833	7	regenerative	regenerative	JJ
cord-022561-rv5j1201	833	8	,	,	,
cord-022561-rv5j1201	833	9	whereas	whereas	IN
cord-022561-rv5j1201	833	10	continued	continue	VBN
cord-022561-rv5j1201	833	11	hemorrhage	hemorrhage	NN
cord-022561-rv5j1201	833	12	and	and	CC
cord-022561-rv5j1201	833	13	iron	iron	NN
cord-022561-rv5j1201	833	14	loss	loss	NN
cord-022561-rv5j1201	833	15	cause	cause	NN
cord-022561-rv5j1201	833	16	nonregenerative	nonregenerative	JJ
cord-022561-rv5j1201	833	17	anemia	anemia	NN
cord-022561-rv5j1201	833	18	.	.	.
cord-022561-rv5j1201	834	1	Additional	additional	JJ
cord-022561-rv5j1201	834	2	hematologic	hematologic	JJ
cord-022561-rv5j1201	834	3	changes	change	NNS
cord-022561-rv5j1201	834	4	may	may	MD
cord-022561-rv5j1201	834	5	include	include	VB
cord-022561-rv5j1201	834	6	evidence	evidence	NN
cord-022561-rv5j1201	834	7	of	of	IN
cord-022561-rv5j1201	834	8	erythrocyte	erythrocyte	NN
cord-022561-rv5j1201	834	9	mechanical	mechanical	JJ
cord-022561-rv5j1201	834	10	fragmentation	fragmentation	NN
cord-022561-rv5j1201	834	11	(	(	-LRB-
cord-022561-rv5j1201	834	12	e.g.	e.g.	RB
cord-022561-rv5j1201	834	13	,	,	,
cord-022561-rv5j1201	834	14	schistocytes	schistocytes	NNP
cord-022561-rv5j1201	834	15	)	)	-RRB-
cord-022561-rv5j1201	834	16	and	and	CC
cord-022561-rv5j1201	834	17	reactive	reactive	JJ
cord-022561-rv5j1201	834	18	thrombocytosis	thrombocytosis	NN
cord-022561-rv5j1201	834	19	.	.	.
cord-022561-rv5j1201	835	1	Hypophosphatemic	Hypophosphatemic	NNP
cord-022561-rv5j1201	835	2	Hemolytic	Hemolytic	NNP
cord-022561-rv5j1201	835	3	Anemia	Anemia	NNP
cord-022561-rv5j1201	835	4	.	.	.
cord-022561-rv5j1201	836	1	Marked	marked	JJ
cord-022561-rv5j1201	836	2	hypophosphatemia	hypophosphatemia	NN
cord-022561-rv5j1201	836	3	is	be	VBZ
cord-022561-rv5j1201	836	4	recognized	recognize	VBN
cord-022561-rv5j1201	836	5	as	as	IN
cord-022561-rv5j1201	836	6	a	a	DT
cord-022561-rv5j1201	836	7	cause	cause	NN
cord-022561-rv5j1201	836	8	of	of	IN
cord-022561-rv5j1201	836	9	intravascular	intravascular	JJ
cord-022561-rv5j1201	836	10	hemolytic	hemolytic	JJ
cord-022561-rv5j1201	836	11	anemia	anemia	NN
cord-022561-rv5j1201	836	12	in	in	IN
cord-022561-rv5j1201	836	13	postparturient	postparturient	NN
cord-022561-rv5j1201	836	14	dairy	dairy	NN
cord-022561-rv5j1201	836	15	cows	cow	NNS
cord-022561-rv5j1201	836	16	and	and	CC
cord-022561-rv5j1201	836	17	diabetic	diabetic	JJ
cord-022561-rv5j1201	836	18	animals	animal	NNS
cord-022561-rv5j1201	836	19	receiving	receive	VBG
cord-022561-rv5j1201	836	20	insulin	insulin	NN
cord-022561-rv5j1201	836	21	therapy	therapy	NN
cord-022561-rv5j1201	836	22	.	.	.
cord-022561-rv5j1201	837	1	In	in	IN
cord-022561-rv5j1201	837	2	postparturient	postparturient	NN
cord-022561-rv5j1201	837	3	cows	cow	NNS
cord-022561-rv5j1201	837	4	,	,	,
cord-022561-rv5j1201	837	5	hypophosphatemia	hypophosphatemia	NN
cord-022561-rv5j1201	837	6	results	result	NNS
cord-022561-rv5j1201	837	7	from	from	IN
cord-022561-rv5j1201	837	8	increased	increase	VBN
cord-022561-rv5j1201	837	9	loss	loss	NN
cord-022561-rv5j1201	837	10	of	of	IN
cord-022561-rv5j1201	837	11	phosphorus	phosphorus	NN
cord-022561-rv5j1201	837	12	in	in	IN
cord-022561-rv5j1201	837	13	their	-PRON-	PRP$
cord-022561-rv5j1201	837	14	milk	milk	NN
cord-022561-rv5j1201	837	15	.	.	.
cord-022561-rv5j1201	838	1	Insulin	insulin	NN
cord-022561-rv5j1201	838	2	therapy	therapy	NN
cord-022561-rv5j1201	838	3	may	may	MD
cord-022561-rv5j1201	838	4	cause	cause	VB
cord-022561-rv5j1201	838	5	hypophosphatemia	hypophosphatemia	NN
cord-022561-rv5j1201	838	6	by	by	IN
cord-022561-rv5j1201	838	7	shifting	shift	VBG
cord-022561-rv5j1201	838	8	phosphorus	phosphorus	NN
cord-022561-rv5j1201	838	9	from	from	IN
cord-022561-rv5j1201	838	10	the	the	DT
cord-022561-rv5j1201	838	11	extracellular	extracellular	JJ
cord-022561-rv5j1201	838	12	space	space	NN
cord-022561-rv5j1201	838	13	to	to	IN
cord-022561-rv5j1201	838	14	the	the	DT
cord-022561-rv5j1201	838	15	intracellular	intracellular	JJ
cord-022561-rv5j1201	838	16	space	space	NN
cord-022561-rv5j1201	838	17	.	.	.
cord-022561-rv5j1201	839	1	In	in	IN
cord-022561-rv5j1201	839	2	either	either	DT
cord-022561-rv5j1201	839	3	case	case	NN
cord-022561-rv5j1201	839	4	,	,	,
cord-022561-rv5j1201	839	5	marked	mark	VBD
cord-022561-rv5j1201	839	6	hypophosphatemia	hypophosphatemia	NN
cord-022561-rv5j1201	840	1	(	(	-LRB-
cord-022561-rv5j1201	840	2	e.g.	e.g.	RB
cord-022561-rv5j1201	840	3	,	,	,
cord-022561-rv5j1201	840	4	1	1	CD
cord-022561-rv5j1201	840	5	mg	mg	NNP
cord-022561-rv5j1201	840	6	/	/	SYM
cord-022561-rv5j1201	840	7	dL	dl	NN
cord-022561-rv5j1201	840	8	in	in	IN
cord-022561-rv5j1201	840	9	cows	cow	NNS
cord-022561-rv5j1201	840	10	,	,	,
cord-022561-rv5j1201	840	11	or	or	CC
cord-022561-rv5j1201	840	12	≤	≤	NNP
cord-022561-rv5j1201	840	13	1.5	1.5	CD
cord-022561-rv5j1201	841	1	mg	mg	NNP
cord-022561-rv5j1201	841	2	/	/	SYM
cord-022561-rv5j1201	841	3	dL	dl	NN
cord-022561-rv5j1201	841	4	in	in	IN
cord-022561-rv5j1201	841	5	cats	cat	NNS
cord-022561-rv5j1201	841	6	)	)	-RRB-
cord-022561-rv5j1201	841	7	is	be	VBZ
cord-022561-rv5j1201	841	8	thought	think	VBN
cord-022561-rv5j1201	841	9	to	to	TO
cord-022561-rv5j1201	841	10	decrease	decrease	VB
cord-022561-rv5j1201	841	11	erythrocyte	erythrocyte	NN
cord-022561-rv5j1201	841	12	production	production	NN
cord-022561-rv5j1201	841	13	of	of	IN
cord-022561-rv5j1201	841	14	ATP	ATP	NNP
cord-022561-rv5j1201	841	15	,	,	,
cord-022561-rv5j1201	841	16	leading	lead	VBG
cord-022561-rv5j1201	841	17	to	to	IN
cord-022561-rv5j1201	841	18	inadequate	inadequate	JJ
cord-022561-rv5j1201	841	19	energy	energy	NN
cord-022561-rv5j1201	841	20	required	require	VBN
cord-022561-rv5j1201	841	21	for	for	IN
cord-022561-rv5j1201	841	22	maintenance	maintenance	NN
cord-022561-rv5j1201	841	23	of	of	IN
cord-022561-rv5j1201	841	24	membrane	membrane	NN
cord-022561-rv5j1201	841	25	and	and	CC
cord-022561-rv5j1201	841	26	cytoskeletal	cytoskeletal	JJ
cord-022561-rv5j1201	841	27	integrity	integrity	NN
cord-022561-rv5j1201	841	28	.	.	.
cord-022561-rv5j1201	842	1	An	an	DT
cord-022561-rv5j1201	842	2	accompanying	accompany	VBG
cord-022561-rv5j1201	842	3	decrease	decrease	NN
cord-022561-rv5j1201	842	4	in	in	IN
cord-022561-rv5j1201	842	5	reducing	reduce	VBG
cord-022561-rv5j1201	842	6	capacity	capacity	NN
cord-022561-rv5j1201	842	7	and	and	CC
cord-022561-rv5j1201	842	8	increase	increase	NN
cord-022561-rv5j1201	842	9	in	in	IN
cord-022561-rv5j1201	842	10	methemoglobin	methemoglobin	JJ
cord-022561-rv5j1201	842	11	concentration	concentration	NN
cord-022561-rv5j1201	842	12	have	have	VBP
cord-022561-rv5j1201	842	13	also	also	RB
cord-022561-rv5j1201	842	14	been	be	VBN
cord-022561-rv5j1201	842	15	noted	note	VBN
cord-022561-rv5j1201	842	16	in	in	IN
cord-022561-rv5j1201	842	17	experimental	experimental	JJ
cord-022561-rv5j1201	842	18	studies	study	NNS
cord-022561-rv5j1201	842	19	of	of	IN
cord-022561-rv5j1201	842	20	hypophosphatemic	hypophosphatemic	JJ
cord-022561-rv5j1201	842	21	hemolytic	hemolytic	JJ
cord-022561-rv5j1201	842	22	anemia	anemia	NN
cord-022561-rv5j1201	842	23	in	in	IN
cord-022561-rv5j1201	842	24	dairy	dairy	NN
cord-022561-rv5j1201	842	25	cattle	cattle	NNS
cord-022561-rv5j1201	842	26	,	,	,
cord-022561-rv5j1201	842	27	suggesting	suggest	VBG
cord-022561-rv5j1201	842	28	that	that	IN
cord-022561-rv5j1201	842	29	oxidative	oxidative	JJ
cord-022561-rv5j1201	842	30	mechanisms	mechanism	NNS
cord-022561-rv5j1201	842	31	may	may	MD
cord-022561-rv5j1201	842	32	also	also	RB
cord-022561-rv5j1201	842	33	contribute	contribute	VB
cord-022561-rv5j1201	842	34	to	to	IN
cord-022561-rv5j1201	842	35	anemia	anemia	NN
cord-022561-rv5j1201	842	36	.	.	.
cord-022561-rv5j1201	843	1	Affected	affected	JJ
cord-022561-rv5j1201	843	2	animals	animal	NNS
cord-022561-rv5j1201	843	3	are	be	VBP
cord-022561-rv5j1201	843	4	anemic	anemic	JJ
cord-022561-rv5j1201	843	5	and	and	CC
cord-022561-rv5j1201	843	6	hemoglobinuric	hemoglobinuric	JJ
cord-022561-rv5j1201	843	7	.	.	.
cord-022561-rv5j1201	844	1	Gross	gross	JJ
cord-022561-rv5j1201	844	2	postmortem	postmortem	JJ
cord-022561-rv5j1201	844	3	findings	finding	NNS
cord-022561-rv5j1201	844	4	include	include	VBP
cord-022561-rv5j1201	844	5	pallor	pallor	NN
cord-022561-rv5j1201	844	6	,	,	,
cord-022561-rv5j1201	844	7	decreased	decrease	VBD
cord-022561-rv5j1201	844	8	viscosity	viscosity	NN
cord-022561-rv5j1201	844	9	of	of	IN
cord-022561-rv5j1201	844	10	the	the	DT
cord-022561-rv5j1201	844	11	blood	blood	NN
cord-022561-rv5j1201	844	12	,	,	,
cord-022561-rv5j1201	844	13	and	and	CC
cord-022561-rv5j1201	844	14	lesions	lesion	NNS
cord-022561-rv5j1201	844	15	arising	arise	VBG
cord-022561-rv5j1201	844	16	from	from	IN
cord-022561-rv5j1201	844	17	the	the	DT
cord-022561-rv5j1201	844	18	underlying	underlie	VBG
cord-022561-rv5j1201	844	19	metabolic	metabolic	JJ
cord-022561-rv5j1201	844	20	derangement	derangement	NN
cord-022561-rv5j1201	844	21	(	(	-LRB-
cord-022561-rv5j1201	844	22	e.g.	e.g.	RB
cord-022561-rv5j1201	844	23	,	,	,
cord-022561-rv5j1201	844	24	discolored	discolor	VBN
cord-022561-rv5j1201	844	25	pale	pale	JJ
cord-022561-rv5j1201	844	26	yellow	yellow	JJ
cord-022561-rv5j1201	844	27	and	and	CC
cord-022561-rv5j1201	844	28	swollen	swollen	JJ
cord-022561-rv5j1201	844	29	liver	liver	NN
cord-022561-rv5j1201	844	30	due	due	IN
cord-022561-rv5j1201	844	31	to	to	IN
cord-022561-rv5j1201	844	32	hepatic	hepatic	JJ
cord-022561-rv5j1201	844	33	lipidosis	lipidosis	NN
cord-022561-rv5j1201	844	34	)	)	-RRB-
cord-022561-rv5j1201	844	35	.	.	.
cord-022561-rv5j1201	845	1	Renal	renal	JJ
cord-022561-rv5j1201	845	2	tubular	tubular	JJ
cord-022561-rv5j1201	845	3	necrosis	necrosis	NN
cord-022561-rv5j1201	845	4	and	and	CC
cord-022561-rv5j1201	845	5	hemoglobin	hemoglobin	NN
cord-022561-rv5j1201	845	6	pigment	pigment	NN
cord-022561-rv5j1201	845	7	within	within	IN
cord-022561-rv5j1201	845	8	the	the	DT
cord-022561-rv5j1201	845	9	tubules	tubule	NNS
cord-022561-rv5j1201	845	10	is	be	VBZ
cord-022561-rv5j1201	845	11	evident	evident	JJ
cord-022561-rv5j1201	845	12	microscopically	microscopically	RB
cord-022561-rv5j1201	845	13	.	.	.
cord-022561-rv5j1201	846	1	This	this	DT
cord-022561-rv5j1201	846	2	section	section	NN
cord-022561-rv5j1201	846	3	covers	cover	VBZ
cord-022561-rv5j1201	846	4	infectious	infectious	JJ
cord-022561-rv5j1201	846	5	agents	agent	NNS
cord-022561-rv5j1201	846	6	within	within	IN
cord-022561-rv5j1201	846	7	the	the	DT
cord-022561-rv5j1201	846	8	same	same	JJ
cord-022561-rv5j1201	846	9	genus	genus	NN
cord-022561-rv5j1201	846	10	that	that	WDT
cord-022561-rv5j1201	846	11	are	be	VBP
cord-022561-rv5j1201	846	12	recognized	recognize	VBN
cord-022561-rv5j1201	846	13	to	to	TO
cord-022561-rv5j1201	846	14	cause	cause	VB
cord-022561-rv5j1201	846	15	disease	disease	NN
cord-022561-rv5j1201	846	16	in	in	IN
cord-022561-rv5j1201	846	17	multiple	multiple	JJ
cord-022561-rv5j1201	846	18	species	specie	NNS
cord-022561-rv5j1201	846	19	.	.	.
cord-022561-rv5j1201	847	1	Other	other	JJ
cord-022561-rv5j1201	847	2	infectious	infectious	JJ
cord-022561-rv5j1201	847	3	agents	agent	NNS
cord-022561-rv5j1201	847	4	with	with	IN
cord-022561-rv5j1201	847	5	more	more	RBR
cord-022561-rv5j1201	847	6	limited	limited	JJ
cord-022561-rv5j1201	847	7	host	host	NN
cord-022561-rv5j1201	847	8	specificity	specificity	NN
cord-022561-rv5j1201	847	9	(	(	-LRB-
cord-022561-rv5j1201	847	10	e.g.	e.g.	RB
cord-022561-rv5j1201	847	11	,	,	,
cord-022561-rv5j1201	847	12	cytauxzoonosis	cytauxzoonosis	NN
cord-022561-rv5j1201	847	13	in	in	IN
cord-022561-rv5j1201	847	14	cats	cat	NNS
cord-022561-rv5j1201	847	15	,	,	,
cord-022561-rv5j1201	847	16	feline	feline	JJ
cord-022561-rv5j1201	847	17	and	and	CC
cord-022561-rv5j1201	847	18	equine	equine	JJ
cord-022561-rv5j1201	847	19	retroviruses	retrovirus	NNS
cord-022561-rv5j1201	847	20	)	)	-RRB-
cord-022561-rv5j1201	847	21	are	be	VBP
cord-022561-rv5j1201	847	22	covered	cover	VBN
cord-022561-rv5j1201	847	23	in	in	IN
cord-022561-rv5j1201	847	24	later	later	JJ
cord-022561-rv5j1201	847	25	sections	section	NNS
cord-022561-rv5j1201	847	26	on	on	IN
cord-022561-rv5j1201	847	27	species	species	NN
cord-022561-rv5j1201	847	28	-	-	HYPH
cord-022561-rv5j1201	847	29	specific	specific	JJ
cord-022561-rv5j1201	847	30	diseases	disease	NNS
cord-022561-rv5j1201	847	31	.	.	.
cord-022561-rv5j1201	848	1	Throughout	throughout	IN
cord-022561-rv5j1201	848	2	both	both	DT
cord-022561-rv5j1201	848	3	sections	section	NNS
cord-022561-rv5j1201	848	4	,	,	,
cord-022561-rv5j1201	848	5	diseases	disease	NNS
cord-022561-rv5j1201	848	6	are	be	VBP
cord-022561-rv5j1201	848	7	•	•	NN
cord-022561-rv5j1201	849	1	Dogs	dog	NNS
cord-022561-rv5j1201	849	2	-	-	HYPH
cord-022561-rv5j1201	849	3	Acetaminophen	acetaminophen	NN
cord-022561-rv5j1201	849	4	,	,	,
cord-022561-rv5j1201	849	5	propofol	propofol	NN
cord-022561-rv5j1201	849	6	,	,	,
cord-022561-rv5j1201	849	7	zinc	zinc	NN
cord-022561-rv5j1201	849	8	•	•	CD
cord-022561-rv5j1201	849	9	Cats	Cats	NNPS
cord-022561-rv5j1201	849	10	-	-	HYPH
cord-022561-rv5j1201	849	11	Acetaminophen	Acetaminophen	NNP
cord-022561-rv5j1201	849	12	,	,	,
cord-022561-rv5j1201	849	13	propofol	propofol	NN
cord-022561-rv5j1201	849	14	,	,	,
cord-022561-rv5j1201	849	15	propylene	propylene	NN
cord-022561-rv5j1201	849	16	glycol	glycol	NN
cord-022561-rv5j1201	850	1	•	•	NNP
cord-022561-rv5j1201	851	1	All	all	DT
cord-022561-rv5j1201	851	2	species	species	NN
cord-022561-rv5j1201	851	3	-	-	HYPH
cord-022561-rv5j1201	851	4	Allium	allium	NN
cord-022561-rv5j1201	851	5	spp	spp	NNS
cord-022561-rv5j1201	851	6	.	.	.
cord-022561-rv5j1201	852	1	(	(	-LRB-
cord-022561-rv5j1201	852	2	chives	chive	NNS
cord-022561-rv5j1201	852	3	,	,	,
cord-022561-rv5j1201	852	4	garlic	garlic	NN
cord-022561-rv5j1201	852	5	,	,	,
cord-022561-rv5j1201	852	6	and	and	CC
cord-022561-rv5j1201	852	7	onions	onion	NNS
cord-022561-rv5j1201	852	8	)	)	-RRB-
cord-022561-rv5j1201	853	1	In	in	IN
cord-022561-rv5j1201	853	2	horses	horse	NNS
cord-022561-rv5j1201	853	3	,	,	,
cord-022561-rv5j1201	853	4	red	red	JJ
cord-022561-rv5j1201	853	5	maple	maple	NN
cord-022561-rv5j1201	853	6	leaves	leave	NNS
cord-022561-rv5j1201	853	7	and	and	CC
cord-022561-rv5j1201	853	8	bark	bark	NN
cord-022561-rv5j1201	853	9	are	be	VBP
cord-022561-rv5j1201	853	10	toxic	toxic	JJ
cord-022561-rv5j1201	853	11	,	,	,
cord-022561-rv5j1201	853	12	especially	especially	RB
cord-022561-rv5j1201	853	13	wilted	wilted	JJ
cord-022561-rv5j1201	853	14	or	or	CC
cord-022561-rv5j1201	853	15	dried	dry	VBN
cord-022561-rv5j1201	853	16	leaves	leave	NNS
cord-022561-rv5j1201	853	17	.	.	.
cord-022561-rv5j1201	854	1	The	the	DT
cord-022561-rv5j1201	854	2	toxic	toxic	JJ
cord-022561-rv5j1201	854	3	principle	principle	NN
cord-022561-rv5j1201	854	4	is	be	VBZ
cord-022561-rv5j1201	854	5	believed	believe	VBN
cord-022561-rv5j1201	854	6	to	to	TO
cord-022561-rv5j1201	854	7	be	be	VB
cord-022561-rv5j1201	854	8	gallic	gallic	JJ
cord-022561-rv5j1201	854	9	acid	acid	NN
cord-022561-rv5j1201	854	10	.	.	.
cord-022561-rv5j1201	855	1	Plants	plant	NNS
cord-022561-rv5j1201	855	2	that	that	WDT
cord-022561-rv5j1201	855	3	contain	contain	VBP
cord-022561-rv5j1201	855	4	high	high	JJ
cord-022561-rv5j1201	855	5	concentrations	concentration	NNS
cord-022561-rv5j1201	855	6	of	of	IN
cord-022561-rv5j1201	855	7	nitrates	nitrate	NNS
cord-022561-rv5j1201	855	8	,	,	,
cord-022561-rv5j1201	855	9	such	such	JJ
cord-022561-rv5j1201	855	10	as	as	IN
cord-022561-rv5j1201	855	11	cabbage	cabbage	NN
cord-022561-rv5j1201	855	12	,	,	,
cord-022561-rv5j1201	855	13	kale	kale	NN
cord-022561-rv5j1201	855	14	,	,	,
cord-022561-rv5j1201	855	15	and	and	CC
cord-022561-rv5j1201	855	16	rape	rape	NN
cord-022561-rv5j1201	855	17	,	,	,
cord-022561-rv5j1201	855	18	may	may	MD
cord-022561-rv5j1201	855	19	cause	cause	VB
cord-022561-rv5j1201	855	20	oxidative	oxidative	JJ
cord-022561-rv5j1201	855	21	injury	injury	NN
cord-022561-rv5j1201	855	22	to	to	IN
cord-022561-rv5j1201	855	23	erythrocytes	erythrocyte	NNS
cord-022561-rv5j1201	855	24	;	;	:
cord-022561-rv5j1201	855	25	cattle	cattle	NNS
cord-022561-rv5j1201	855	26	are	be	VBP
cord-022561-rv5j1201	855	27	more	more	RBR
cord-022561-rv5j1201	855	28	susceptible	susceptible	JJ
cord-022561-rv5j1201	855	29	than	than	IN
cord-022561-rv5j1201	855	30	sheep	sheep	NNS
cord-022561-rv5j1201	855	31	and	and	CC
cord-022561-rv5j1201	855	32	goats	goat	NNS
cord-022561-rv5j1201	855	33	.	.	.
cord-022561-rv5j1201	856	1	However	however	RB
cord-022561-rv5j1201	856	2	,	,	,
cord-022561-rv5j1201	856	3	sheep	sheep	NNS
cord-022561-rv5j1201	856	4	are	be	VBP
cord-022561-rv5j1201	856	5	more	more	RBR
cord-022561-rv5j1201	856	6	prone	prone	JJ
cord-022561-rv5j1201	856	7	to	to	IN
cord-022561-rv5j1201	856	8	copper	copper	NN
cord-022561-rv5j1201	856	9	toxicosis	toxicosis	NN
cord-022561-rv5j1201	856	10	relative	relative	JJ
cord-022561-rv5j1201	856	11	to	to	IN
cord-022561-rv5j1201	856	12	other	other	JJ
cord-022561-rv5j1201	856	13	ruminants	ruminant	NNS
cord-022561-rv5j1201	856	14	.	.	.
cord-022561-rv5j1201	857	1	The	the	DT
cord-022561-rv5j1201	857	2	condition	condition	NN
cord-022561-rv5j1201	857	3	occurs	occur	VBZ
cord-022561-rv5j1201	857	4	in	in	IN
cord-022561-rv5j1201	857	5	animals	animal	NNS
cord-022561-rv5j1201	857	6	that	that	WDT
cord-022561-rv5j1201	857	7	have	have	VBP
cord-022561-rv5j1201	857	8	chronically	chronically	RB
cord-022561-rv5j1201	857	9	accumulated	accumulate	VBN
cord-022561-rv5j1201	857	10	large	large	JJ
cord-022561-rv5j1201	857	11	amounts	amount	NNS
cord-022561-rv5j1201	857	12	of	of	IN
cord-022561-rv5j1201	857	13	copper	copper	NN
cord-022561-rv5j1201	857	14	in	in	IN
cord-022561-rv5j1201	857	15	the	the	DT
cord-022561-rv5j1201	857	16	liver	liver	NN
cord-022561-rv5j1201	857	17	through	through	IN
cord-022561-rv5j1201	857	18	the	the	DT
cord-022561-rv5j1201	857	19	diet	diet	NN
cord-022561-rv5j1201	857	20	.	.	.
cord-022561-rv5j1201	858	1	The	the	DT
cord-022561-rv5j1201	858	2	copper	copper	NN
cord-022561-rv5j1201	858	3	is	be	VBZ
cord-022561-rv5j1201	858	4	then	then	RB
cord-022561-rv5j1201	858	5	acutely	acutely	RB
cord-022561-rv5j1201	858	6	released	release	VBN
cord-022561-rv5j1201	858	7	during	during	IN
cord-022561-rv5j1201	858	8	conditions	condition	NNS
cord-022561-rv5j1201	858	9	of	of	IN
cord-022561-rv5j1201	858	10	stress	stress	NN
cord-022561-rv5j1201	858	11	,	,	,
cord-022561-rv5j1201	858	12	such	such	JJ
cord-022561-rv5j1201	858	13	as	as	IN
cord-022561-rv5j1201	858	14	shipping	shipping	NN
cord-022561-rv5j1201	858	15	or	or	CC
cord-022561-rv5j1201	858	16	starvation	starvation	NN
cord-022561-rv5j1201	858	17	.	.	.
cord-022561-rv5j1201	859	1	Continuous	continuous	JJ
cord-022561-rv5j1201	859	2	rate	rate	NN
cord-022561-rv5j1201	859	3	infusions	infusion	NNS
cord-022561-rv5j1201	859	4	of	of	IN
cord-022561-rv5j1201	859	5	the	the	DT
cord-022561-rv5j1201	859	6	anesthetic	anesthetic	NN
cord-022561-rv5j1201	859	7	propofol	propofol	NN
cord-022561-rv5j1201	859	8	may	may	MD
cord-022561-rv5j1201	859	9	cause	cause	VB
cord-022561-rv5j1201	859	10	oxidative	oxidative	JJ
cord-022561-rv5j1201	859	11	hemolytic	hemolytic	JJ
cord-022561-rv5j1201	859	12	anemia	anemia	NN
cord-022561-rv5j1201	859	13	in	in	IN
cord-022561-rv5j1201	859	14	dogs	dog	NNS
cord-022561-rv5j1201	859	15	and	and	CC
cord-022561-rv5j1201	859	16	cats	cat	NNS
cord-022561-rv5j1201	859	17	,	,	,
cord-022561-rv5j1201	859	18	but	but	CC
cord-022561-rv5j1201	860	1	single	single	JJ
cord-022561-rv5j1201	860	2	or	or	CC
cord-022561-rv5j1201	860	3	multiple	multiple	JJ
cord-022561-rv5j1201	860	4	single	single	JJ
cord-022561-rv5j1201	860	5	doses	dose	NNS
cord-022561-rv5j1201	860	6	are	be	VBP
cord-022561-rv5j1201	860	7	not	not	RB
cord-022561-rv5j1201	860	8	expected	expect	VBN
cord-022561-rv5j1201	860	9	to	to	TO
cord-022561-rv5j1201	860	10	cause	cause	VB
cord-022561-rv5j1201	860	11	clinical	clinical	JJ
cord-022561-rv5j1201	860	12	hemolysis	hemolysis	NN
cord-022561-rv5j1201	860	13	.	.	.
cord-022561-rv5j1201	861	1	Zinc	zinc	NN
cord-022561-rv5j1201	861	2	toxicosis	toxicosis	NN
cord-022561-rv5j1201	861	3	has	have	VBZ
cord-022561-rv5j1201	861	4	been	be	VBN
cord-022561-rv5j1201	861	5	identified	identify	VBN
cord-022561-rv5j1201	861	6	in	in	IN
cord-022561-rv5j1201	861	7	a	a	DT
cord-022561-rv5j1201	861	8	wide	wide	JJ
cord-022561-rv5j1201	861	9	range	range	NN
cord-022561-rv5j1201	861	10	of	of	IN
cord-022561-rv5j1201	861	11	animals	animal	NNS
cord-022561-rv5j1201	861	12	;	;	:
cord-022561-rv5j1201	861	13	however	however	RB
cord-022561-rv5j1201	861	14	,	,	,
cord-022561-rv5j1201	861	15	it	-PRON-	PRP
cord-022561-rv5j1201	861	16	is	be	VBZ
cord-022561-rv5j1201	861	17	most	most	RBS
cord-022561-rv5j1201	861	18	common	common	JJ
cord-022561-rv5j1201	861	19	in	in	IN
cord-022561-rv5j1201	861	20	dogs	dog	NNS
cord-022561-rv5j1201	861	21	due	due	JJ
cord-022561-rv5j1201	861	22	to	to	IN
cord-022561-rv5j1201	861	23	their	-PRON-	PRP$
cord-022561-rv5j1201	861	24	indiscriminate	indiscriminate	JJ
cord-022561-rv5j1201	861	25	eating	eat	VBG
cord-022561-rv5j1201	861	26	habits	habit	NNS
cord-022561-rv5j1201	861	27	.	.	.
cord-022561-rv5j1201	862	1	Common	common	JJ
cord-022561-rv5j1201	862	2	sources	source	NNS
cord-022561-rv5j1201	862	3	include	include	VBP
cord-022561-rv5j1201	862	4	pennies	penny	NNS
cord-022561-rv5j1201	862	5	,	,	,
cord-022561-rv5j1201	862	6	batteries	battery	NNS
cord-022561-rv5j1201	862	7	,	,	,
cord-022561-rv5j1201	862	8	paints	paint	NNS
cord-022561-rv5j1201	862	9	,	,	,
cord-022561-rv5j1201	862	10	creams	cream	NNS
cord-022561-rv5j1201	862	11	,	,	,
cord-022561-rv5j1201	862	12	automotive	automotive	JJ
cord-022561-rv5j1201	862	13	parts	part	NNS
cord-022561-rv5j1201	862	14	,	,	,
cord-022561-rv5j1201	862	15	screws	screw	NNS
cord-022561-rv5j1201	862	16	,	,	,
cord-022561-rv5j1201	862	17	nuts	nut	NNS
cord-022561-rv5j1201	862	18	,	,	,
cord-022561-rv5j1201	862	19	and	and	CC
cord-022561-rv5j1201	862	20	coating	coat	VBG
cord-022561-rv5j1201	862	21	on	on	IN
cord-022561-rv5j1201	862	22	galvanized	galvanize	VBN
cord-022561-rv5j1201	862	23	metals	metal	NNS
cord-022561-rv5j1201	862	24	.	.	.
cord-022561-rv5j1201	863	1	Propylene	propylene	NN
cord-022561-rv5j1201	863	2	glycol	glycol	NN
cord-022561-rv5j1201	863	3	is	be	VBZ
cord-022561-rv5j1201	863	4	an	an	DT
cord-022561-rv5j1201	863	5	odorless	odorless	JJ
cord-022561-rv5j1201	863	6	,	,	,
cord-022561-rv5j1201	863	7	slightly	slightly	RB
cord-022561-rv5j1201	863	8	sweet	sweet	JJ
cord-022561-rv5j1201	863	9	solvent	solvent	NN
cord-022561-rv5j1201	863	10	and	and	CC
cord-022561-rv5j1201	863	11	moistening	moisten	VBG
cord-022561-rv5j1201	863	12	agent	agent	NN
cord-022561-rv5j1201	863	13	in	in	IN
cord-022561-rv5j1201	863	14	many	many	JJ
cord-022561-rv5j1201	863	15	foods	food	NNS
cord-022561-rv5j1201	863	16	,	,	,
cord-022561-rv5j1201	863	17	drugs	drug	NNS
cord-022561-rv5j1201	863	18	,	,	,
cord-022561-rv5j1201	863	19	and	and	CC
cord-022561-rv5j1201	863	20	tobacco	tobacco	NN
cord-022561-rv5j1201	863	21	products	product	NNS
cord-022561-rv5j1201	863	22	.	.	.
cord-022561-rv5j1201	864	1	Although	although	IN
cord-022561-rv5j1201	864	2	it	-PRON-	PRP
cord-022561-rv5j1201	864	3	is	be	VBZ
cord-022561-rv5j1201	864	4	"	"	``
cord-022561-rv5j1201	864	5	generally	generally	RB
cord-022561-rv5j1201	864	6	recognized	recognize	VBN
cord-022561-rv5j1201	864	7	as	as	RB
cord-022561-rv5j1201	864	8	safe	safe	JJ
cord-022561-rv5j1201	864	9	"	"	''
cord-022561-rv5j1201	864	10	for	for	IN
cord-022561-rv5j1201	864	11	animal	animal	NN
cord-022561-rv5j1201	864	12	foods	food	NNS
cord-022561-rv5j1201	864	13	other	other	JJ
cord-022561-rv5j1201	864	14	than	than	IN
cord-022561-rv5j1201	864	15	for	for	IN
cord-022561-rv5j1201	864	16	cats	cat	NNS
cord-022561-rv5j1201	864	17	by	by	IN
cord-022561-rv5j1201	864	18	the	the	DT
cord-022561-rv5j1201	864	19	Food	Food	NNP
cord-022561-rv5j1201	864	20	and	and	CC
cord-022561-rv5j1201	864	21	Drug	Drug	NNP
cord-022561-rv5j1201	864	22	Administration	Administration	NNP
cord-022561-rv5j1201	864	23	,	,	,
cord-022561-rv5j1201	864	24	it	-PRON-	PRP
cord-022561-rv5j1201	864	25	has	have	VBZ
cord-022561-rv5j1201	864	26	been	be	VBN
cord-022561-rv5j1201	864	27	banned	ban	VBN
cord-022561-rv5j1201	864	28	from	from	IN
cord-022561-rv5j1201	864	29	cat	cat	NN
cord-022561-rv5j1201	864	30	food	food	NN
cord-022561-rv5j1201	864	31	since	since	IN
cord-022561-rv5j1201	864	32	1996	1996	CD
cord-022561-rv5j1201	864	33	.	.	.
cord-022561-rv5j1201	865	1	Grossly	grossly	RB
cord-022561-rv5j1201	865	2	and	and	CC
cord-022561-rv5j1201	865	3	microscopically	microscopically	RB
cord-022561-rv5j1201	865	4	,	,	,
cord-022561-rv5j1201	865	5	animals	animal	NNS
cord-022561-rv5j1201	865	6	show	show	VBP
cord-022561-rv5j1201	865	7	varying	vary	VBG
cord-022561-rv5j1201	865	8	signs	sign	NNS
cord-022561-rv5j1201	865	9	of	of	IN
cord-022561-rv5j1201	865	10	oxidative	oxidative	JJ
cord-022561-rv5j1201	865	11	hemolysis	hemolysis	NN
cord-022561-rv5j1201	865	12	and/or	and/or	CC
cord-022561-rv5j1201	865	13	methemoglobinemia	methemoglobinemia	NN
cord-022561-rv5j1201	865	14	,	,	,
cord-022561-rv5j1201	865	15	as	as	IN
cord-022561-rv5j1201	865	16	previously	previously	RB
cord-022561-rv5j1201	865	17	presented	present	VBN
cord-022561-rv5j1201	865	18	in	in	IN
cord-022561-rv5j1201	865	19	the	the	DT
cord-022561-rv5j1201	865	20	section	section	NN
cord-022561-rv5j1201	865	21	discussing	discuss	VBG
cord-022561-rv5j1201	865	22	anemias	anemia	NNS
cord-022561-rv5j1201	865	23	(	(	-LRB-
cord-022561-rv5j1201	865	24	see	see	VB
cord-022561-rv5j1201	865	25	Bone	Bone	NNP
cord-022561-rv5j1201	865	26	Marrow	Marrow	NNP
cord-022561-rv5j1201	865	27	and	and	CC
cord-022561-rv5j1201	865	28	Blood	blood	NN
cord-022561-rv5j1201	865	29	Cells	cell	NNS
cord-022561-rv5j1201	865	30	,	,	,
cord-022561-rv5j1201	865	31	Dysfunction	dysfunction	NN
cord-022561-rv5j1201	865	32	/	/	SYM
cord-022561-rv5j1201	865	33	Responses	response	NNS
cord-022561-rv5j1201	865	34	to	to	IN
cord-022561-rv5j1201	865	35	Injury	injury	NN
cord-022561-rv5j1201	865	36	,	,	,
cord-022561-rv5j1201	865	37	Blood	blood	NN
cord-022561-rv5j1201	865	38	Cells	cell	NNS
cord-022561-rv5j1201	865	39	,	,	,
cord-022561-rv5j1201	865	40	Abnormal	abnormal	JJ
cord-022561-rv5j1201	865	41	Concentrations	concentration	NNS
cord-022561-rv5j1201	865	42	of	of	IN
cord-022561-rv5j1201	865	43	Blood	blood	NN
cord-022561-rv5j1201	865	44	Cells	cell	NNS
cord-022561-rv5j1201	865	45	,	,	,
cord-022561-rv5j1201	865	46	Anemia	anemia	NN
cord-022561-rv5j1201	865	47	)	)	-RRB-
cord-022561-rv5j1201	865	48	.	.	.
cord-022561-rv5j1201	866	1	In	in	IN
cord-022561-rv5j1201	866	2	sheep	sheep	NNS
cord-022561-rv5j1201	866	3	with	with	IN
cord-022561-rv5j1201	866	4	copper	copper	NN
cord-022561-rv5j1201	866	5	toxicosis	toxicosis	NN
cord-022561-rv5j1201	866	6	,	,	,
cord-022561-rv5j1201	866	7	hemoglobinuric	hemoglobinuric	NNP
cord-022561-rv5j1201	866	8	nephrosis	nephrosis	NNP
cord-022561-rv5j1201	866	9	,	,	,
cord-022561-rv5j1201	866	10	frequently	frequently	RB
cord-022561-rv5j1201	866	11	described	describe	VBN
cord-022561-rv5j1201	866	12	as	as	IN
cord-022561-rv5j1201	866	13	gunmetal	gunmetal	JJ
cord-022561-rv5j1201	866	14	-	-	HYPH
cord-022561-rv5j1201	866	15	colored	color	VBN
cord-022561-rv5j1201	866	16	kidneys	kidney	NNS
cord-022561-rv5j1201	866	17	with	with	IN
cord-022561-rv5j1201	866	18	port	port	NN
cord-022561-rv5j1201	866	19	wine	wine	NN
cord-022561-rv5j1201	866	20	-	-	HYPH
cord-022561-rv5j1201	866	21	colored	color	VBN
cord-022561-rv5j1201	866	22	urine	urine	NN
cord-022561-rv5j1201	866	23	,	,	,
cord-022561-rv5j1201	866	24	is	be	VBZ
cord-022561-rv5j1201	866	25	a	a	DT
cord-022561-rv5j1201	866	26	classic	classic	JJ
cord-022561-rv5j1201	866	27	postmortem	postmortem	JJ
cord-022561-rv5j1201	866	28	lesion	lesion	NN
cord-022561-rv5j1201	866	29	.	.	.
cord-022561-rv5j1201	867	1	Snake	Snake	NNP
cord-022561-rv5j1201	867	2	Envenomation	Envenomation	NNP
cord-022561-rv5j1201	867	3	.	.	.
cord-022561-rv5j1201	868	1	Hemolytic	hemolytic	JJ
cord-022561-rv5j1201	868	2	anemia	anemia	NN
cord-022561-rv5j1201	868	3	from	from	IN
cord-022561-rv5j1201	868	4	snake	snake	NN
cord-022561-rv5j1201	868	5	envenomation	envenomation	NN
cord-022561-rv5j1201	868	6	has	have	VBZ
cord-022561-rv5j1201	868	7	been	be	VBN
cord-022561-rv5j1201	868	8	reported	report	VBN
cord-022561-rv5j1201	868	9	in	in	IN
cord-022561-rv5j1201	868	10	horses	horse	NNS
cord-022561-rv5j1201	868	11	,	,	,
cord-022561-rv5j1201	868	12	dogs	dog	NNS
cord-022561-rv5j1201	868	13	,	,	,
cord-022561-rv5j1201	868	14	and	and	CC
cord-022561-rv5j1201	868	15	cats	cat	NNS
cord-022561-rv5j1201	868	16	.	.	.
cord-022561-rv5j1201	869	1	It	-PRON-	PRP
cord-022561-rv5j1201	869	2	is	be	VBZ
cord-022561-rv5j1201	869	3	most	most	RBS
cord-022561-rv5j1201	869	4	commonly	commonly	RB
cord-022561-rv5j1201	869	5	reported	report	VBN
cord-022561-rv5j1201	869	6	with	with	IN
cord-022561-rv5j1201	869	7	viper	viper	NN
cord-022561-rv5j1201	869	8	and	and	CC
cord-022561-rv5j1201	869	9	pit	pit	NNP
cord-022561-rv5j1201	869	10	viper	viper	NNP
cord-022561-rv5j1201	869	11	envenomations	envenomations	NNP
cord-022561-rv5j1201	869	12	,	,	,
cord-022561-rv5j1201	869	13	including	include	VBG
cord-022561-rv5j1201	869	14	those	those	DT
cord-022561-rv5j1201	869	15	from	from	IN
cord-022561-rv5j1201	869	16	rattlesnakes	rattlesnake	NNS
cord-022561-rv5j1201	869	17	.	.	.
cord-022561-rv5j1201	870	1	Hemolysins	Hemolysins	NNP
cord-022561-rv5j1201	870	2	within	within	IN
cord-022561-rv5j1201	870	3	viper	viper	NN
cord-022561-rv5j1201	870	4	venom	venom	NN
cord-022561-rv5j1201	870	5	directly	directly	RB
cord-022561-rv5j1201	870	6	injure	injure	VB
cord-022561-rv5j1201	870	7	erythrocytes	erythrocyte	NNS
cord-022561-rv5j1201	870	8	,	,	,
cord-022561-rv5j1201	870	9	causing	cause	VBG
cord-022561-rv5j1201	870	10	intravascular	intravascular	JJ
cord-022561-rv5j1201	870	11	hemolysis	hemolysis	NN
cord-022561-rv5j1201	870	12	.	.	.
cord-022561-rv5j1201	871	1	Other	other	JJ
cord-022561-rv5j1201	871	2	mechanisms	mechanism	NNS
cord-022561-rv5j1201	871	3	of	of	IN
cord-022561-rv5j1201	871	4	hemolysis	hemolysis	NN
cord-022561-rv5j1201	871	5	include	include	VBP
cord-022561-rv5j1201	871	6	the	the	DT
cord-022561-rv5j1201	871	7	action	action	NN
cord-022561-rv5j1201	871	8	of	of	IN
cord-022561-rv5j1201	871	9	phospholipase	phospholipase	NN
cord-022561-rv5j1201	871	10	A	a	DT
cord-022561-rv5j1201	871	11	2	2	CD
cord-022561-rv5j1201	871	12	on	on	IN
cord-022561-rv5j1201	871	13	erythrocyte	erythrocyte	NN
cord-022561-rv5j1201	871	14	membranes	membrane	NNS
cord-022561-rv5j1201	871	15	and	and	CC
cord-022561-rv5j1201	871	16	erythrocyte	erythrocyte	NN
cord-022561-rv5j1201	871	17	mechanical	mechanical	JJ
cord-022561-rv5j1201	871	18	fragmentation	fragmentation	NN
cord-022561-rv5j1201	871	19	due	due	IN
cord-022561-rv5j1201	871	20	to	to	IN
cord-022561-rv5j1201	871	21	intravascular	intravascular	JJ
cord-022561-rv5j1201	871	22	coagulation	coagulation	NN
cord-022561-rv5j1201	871	23	and	and	CC
cord-022561-rv5j1201	871	24	vasculitis	vasculitis	NN
cord-022561-rv5j1201	871	25	.	.	.
cord-022561-rv5j1201	872	1	Nonhemolytic	nonhemolytic	JJ
cord-022561-rv5j1201	872	2	lesions	lesion	NNS
cord-022561-rv5j1201	872	3	depend	depend	VBP
cord-022561-rv5j1201	872	4	on	on	IN
cord-022561-rv5j1201	872	5	the	the	DT
cord-022561-rv5j1201	872	6	venom	venom	NN
cord-022561-rv5j1201	872	7	's	's	POS
cord-022561-rv5j1201	872	8	additional	additional	JJ
cord-022561-rv5j1201	872	9	components	component	NNS
cord-022561-rv5j1201	872	10	and	and	CC
cord-022561-rv5j1201	872	11	may	may	MD
cord-022561-rv5j1201	872	12	include	include	VB
cord-022561-rv5j1201	872	13	hemorrhage	hemorrhage	NN
cord-022561-rv5j1201	872	14	,	,	,
cord-022561-rv5j1201	872	15	paralysis	paralysis	NN
cord-022561-rv5j1201	872	16	,	,	,
cord-022561-rv5j1201	872	17	and/or	and/or	CC
cord-022561-rv5j1201	872	18	tissue	tissue	NN
cord-022561-rv5j1201	872	19	edema	edema	NN
cord-022561-rv5j1201	872	20	,	,	,
cord-022561-rv5j1201	872	21	inflammation	inflammation	NN
cord-022561-rv5j1201	872	22	,	,	,
cord-022561-rv5j1201	872	23	and	and	CC
cord-022561-rv5j1201	872	24	necrosis	necrosis	NN
cord-022561-rv5j1201	872	25	.	.	.
cord-022561-rv5j1201	873	1	On	on	IN
cord-022561-rv5j1201	873	2	blood	blood	NN
cord-022561-rv5j1201	873	3	smear	smear	NN
cord-022561-rv5j1201	873	4	evaluation	evaluation	NN
cord-022561-rv5j1201	873	5	,	,	,
cord-022561-rv5j1201	873	6	animals	animal	NNS
cord-022561-rv5j1201	873	7	with	with	IN
cord-022561-rv5j1201	873	8	snake	snake	NN
cord-022561-rv5j1201	873	9	envenomation	envenomation	NN
cord-022561-rv5j1201	873	10	may	may	MD
cord-022561-rv5j1201	873	11	have	have	VB
cord-022561-rv5j1201	873	12	ghost	ghost	NN
cord-022561-rv5j1201	873	13	cells	cell	NNS
cord-022561-rv5j1201	873	14	,	,	,
cord-022561-rv5j1201	873	15	spherocytes	spherocyte	NNS
cord-022561-rv5j1201	873	16	,	,	,
cord-022561-rv5j1201	873	17	and/or	and/or	CC
cord-022561-rv5j1201	873	18	echinocytes	echinocytes	NNP
cord-022561-rv5j1201	873	19	(	(	-LRB-
cord-022561-rv5j1201	873	20	see	see	VB
cord-022561-rv5j1201	873	21	Figs	fig	NNS
cord-022561-rv5j1201	873	22	.	.	.
cord-022561-rv5j1201	874	1	13	13	CD
cord-022561-rv5j1201	874	2	-	-	SYM
cord-022561-rv5j1201	874	3	13	13	CD
cord-022561-rv5j1201	874	4	and	and	CC
cord-022561-rv5j1201	874	5	13	13	CD
cord-022561-rv5j1201	874	6	-	-	SYM
cord-022561-rv5j1201	874	7	15	15	CD
cord-022561-rv5j1201	874	8	)	)	-RRB-
cord-022561-rv5j1201	874	9	.	.	.
cord-022561-rv5j1201	875	1	Information	information	NN
cord-022561-rv5j1201	875	2	on	on	IN
cord-022561-rv5j1201	875	3	this	this	DT
cord-022561-rv5j1201	875	4	topic	topic	NN
cord-022561-rv5j1201	875	5	is	be	VBZ
cord-022561-rv5j1201	875	6	available	available	JJ
cord-022561-rv5j1201	875	7	at	at	IN
cord-022561-rv5j1201	875	8	www.expertconsult.com	www.expertconsult.com	ADD
cord-022561-rv5j1201	875	9	.	.	.
cord-022561-rv5j1201	876	1	Severe	severe	JJ
cord-022561-rv5j1201	876	2	malnutrition	malnutrition	NN
cord-022561-rv5j1201	876	3	is	be	VBZ
cord-022561-rv5j1201	876	4	probably	probably	RB
cord-022561-rv5j1201	876	5	a	a	DT
cord-022561-rv5j1201	876	6	cause	cause	NN
cord-022561-rv5j1201	876	7	of	of	IN
cord-022561-rv5j1201	876	8	nonregenerative	nonregenerative	JJ
cord-022561-rv5j1201	876	9	anemia	anemia	NN
cord-022561-rv5j1201	876	10	in	in	IN
cord-022561-rv5j1201	876	11	all	all	DT
cord-022561-rv5j1201	876	12	species	specie	NNS
cord-022561-rv5j1201	876	13	attributable	attributable	JJ
cord-022561-rv5j1201	876	14	to	to	IN
cord-022561-rv5j1201	876	15	combined	combine	VBN
cord-022561-rv5j1201	876	16	deficiencies	deficiency	NNS
cord-022561-rv5j1201	876	17	of	of	IN
cord-022561-rv5j1201	876	18	molecular	molecular	JJ
cord-022561-rv5j1201	876	19	building	building	NN
cord-022561-rv5j1201	876	20	blocks	block	NNS
cord-022561-rv5j1201	876	21	,	,	,
cord-022561-rv5j1201	876	22	energy	energy	NN
cord-022561-rv5j1201	876	23	,	,	,
cord-022561-rv5j1201	876	24	and	and	CC
cord-022561-rv5j1201	876	25	essential	essential	JJ
cord-022561-rv5j1201	876	26	cofactors	cofactor	NNS
cord-022561-rv5j1201	876	27	.	.	.
cord-022561-rv5j1201	877	1	By	by	IN
cord-022561-rv5j1201	877	2	far	far	RB
cord-022561-rv5j1201	877	3	the	the	DT
cord-022561-rv5j1201	877	4	most	most	RBS
cord-022561-rv5j1201	877	5	commonly	commonly	RB
cord-022561-rv5j1201	877	6	recognized	recognize	VBN
cord-022561-rv5j1201	877	7	specific	specific	JJ
cord-022561-rv5j1201	877	8	deficiency	deficiency	NN
cord-022561-rv5j1201	877	9	that	that	WDT
cord-022561-rv5j1201	877	10	results	result	VBZ
cord-022561-rv5j1201	877	11	in	in	IN
cord-022561-rv5j1201	877	12	anemia	anemia	NN
cord-022561-rv5j1201	877	13	is	be	VBZ
cord-022561-rv5j1201	877	14	iron	iron	NN
cord-022561-rv5j1201	877	15	deficiency	deficiency	NN
cord-022561-rv5j1201	877	16	.	.	.
cord-022561-rv5j1201	878	1	Other	other	JJ
cord-022561-rv5j1201	878	2	specific	specific	JJ
cord-022561-rv5j1201	878	3	nutritional	nutritional	JJ
cord-022561-rv5j1201	878	4	deficiencies	deficiency	NNS
cord-022561-rv5j1201	878	5	causing	cause	VBG
cord-022561-rv5j1201	878	6	anemia	anemia	NN
cord-022561-rv5j1201	878	7	in	in	IN
cord-022561-rv5j1201	878	8	animals	animal	NNS
cord-022561-rv5j1201	878	9	are	be	VBP
cord-022561-rv5j1201	878	10	uncommon	uncommon	JJ
cord-022561-rv5j1201	878	11	or	or	CC
cord-022561-rv5j1201	878	12	rare	rare	JJ
cord-022561-rv5j1201	878	13	.	.	.
cord-022561-rv5j1201	879	1	Acquired	acquire	VBN
cord-022561-rv5j1201	879	2	cobalamin	cobalamin	NN
cord-022561-rv5j1201	879	3	(	(	-LRB-
cord-022561-rv5j1201	879	4	vitamin	vitamin	NN
cord-022561-rv5j1201	879	5	B	B	NNP
cord-022561-rv5j1201	879	6	12	12	CD
cord-022561-rv5j1201	879	7	)	)	-RRB-
cord-022561-rv5j1201	879	8	and	and	CC
cord-022561-rv5j1201	879	9	folate	folate	JJ
cord-022561-rv5j1201	879	10	deficiencies	deficiency	NNS
cord-022561-rv5j1201	879	11	are	be	VBP
cord-022561-rv5j1201	879	12	recognized	recognize	VBN
cord-022561-rv5j1201	879	13	as	as	IN
cord-022561-rv5j1201	879	14	causes	cause	NNS
cord-022561-rv5j1201	879	15	of	of	IN
cord-022561-rv5j1201	879	16	anemia	anemia	NN
cord-022561-rv5j1201	879	17	in	in	IN
cord-022561-rv5j1201	879	18	human	human	JJ
cord-022561-rv5j1201	879	19	beings	being	NNS
cord-022561-rv5j1201	879	20	but	but	CC
cord-022561-rv5j1201	879	21	are	be	VBP
cord-022561-rv5j1201	879	22	rare	rare	JJ
cord-022561-rv5j1201	879	23	in	in	IN
cord-022561-rv5j1201	879	24	animals	animal	NNS
cord-022561-rv5j1201	879	25	.	.	.
cord-022561-rv5j1201	880	1	Iron	iron	NN
cord-022561-rv5j1201	880	2	Deficiency	deficiency	NN
cord-022561-rv5j1201	880	3	Anemia	anemia	NN
cord-022561-rv5j1201	880	4	.	.	.
cord-022561-rv5j1201	881	1	Iron	iron	NN
cord-022561-rv5j1201	881	2	deficiency	deficiency	NN
cord-022561-rv5j1201	881	3	is	be	VBZ
cord-022561-rv5j1201	881	4	usually	usually	RB
cord-022561-rv5j1201	881	5	not	not	RB
cord-022561-rv5j1201	881	6	a	a	DT
cord-022561-rv5j1201	881	7	primary	primary	JJ
cord-022561-rv5j1201	881	8	nutritional	nutritional	JJ
cord-022561-rv5j1201	881	9	deficiency	deficiency	NN
cord-022561-rv5j1201	881	10	but	but	CC
cord-022561-rv5j1201	881	11	rather	rather	RB
cord-022561-rv5j1201	881	12	occurs	occur	VBZ
cord-022561-rv5j1201	881	13	secondary	secondary	JJ
cord-022561-rv5j1201	881	14	to	to	IN
cord-022561-rv5j1201	881	15	depletion	depletion	NN
cord-022561-rv5j1201	881	16	of	of	IN
cord-022561-rv5j1201	881	17	iron	iron	NN
cord-022561-rv5j1201	881	18	stores	store	NNS
cord-022561-rv5j1201	881	19	via	via	IN
cord-022561-rv5j1201	881	20	chronic	chronic	JJ
cord-022561-rv5j1201	881	21	blood	blood	NN
cord-022561-rv5j1201	881	22	loss	loss	NN
cord-022561-rv5j1201	881	23	.	.	.
cord-022561-rv5j1201	882	1	The	the	DT
cord-022561-rv5j1201	882	2	most	most	RBS
cord-022561-rv5j1201	882	3	common	common	JJ
cord-022561-rv5j1201	882	4	route	route	NN
cord-022561-rv5j1201	882	5	747.e1	747.e1	CD
cord-022561-rv5j1201	882	6	CHAPTER	chapter	NN
cord-022561-rv5j1201	882	7	13	13	CD
cord-022561-rv5j1201	882	8	Bone	Bone	NNP
cord-022561-rv5j1201	882	9	Marrow	Marrow	NNP
cord-022561-rv5j1201	882	10	,	,	,
cord-022561-rv5j1201	882	11	Blood	blood	NN
cord-022561-rv5j1201	882	12	Cells	cell	NNS
cord-022561-rv5j1201	882	13	,	,	,
cord-022561-rv5j1201	882	14	and	and	CC
cord-022561-rv5j1201	882	15	the	the	DT
cord-022561-rv5j1201	882	16	Lymphoid	Lymphoid	NNP
cord-022561-rv5j1201	882	17	/	/	SYM
cord-022561-rv5j1201	882	18	Lymphatic	Lymphatic	NNP
cord-022561-rv5j1201	882	19	System	System	NNP
cord-022561-rv5j1201	882	20	Antagonism	Antagonism	NNP
cord-022561-rv5j1201	882	21	of	of	IN
cord-022561-rv5j1201	882	22	vitamin	vitamin	NN
cord-022561-rv5j1201	882	23	K	k	NN
cord-022561-rv5j1201	882	24	leads	lead	VBZ
cord-022561-rv5j1201	882	25	to	to	IN
cord-022561-rv5j1201	882	26	production	production	NN
cord-022561-rv5j1201	882	27	of	of	IN
cord-022561-rv5j1201	882	28	a	a	DT
cord-022561-rv5j1201	882	29	nonfunctional	nonfunctional	JJ
cord-022561-rv5j1201	882	30	form	form	NN
cord-022561-rv5j1201	882	31	of	of	IN
cord-022561-rv5j1201	882	32	some	some	DT
cord-022561-rv5j1201	882	33	coagulation	coagulation	NN
cord-022561-rv5j1201	882	34	factors	factor	NNS
cord-022561-rv5j1201	882	35	and	and	CC
cord-022561-rv5j1201	882	36	resulting	result	VBG
cord-022561-rv5j1201	882	37	coagulopathy	coagulopathy	NN
cord-022561-rv5j1201	882	38	;	;	:
cord-022561-rv5j1201	882	39	a	a	DT
cord-022561-rv5j1201	882	40	similar	similar	JJ
cord-022561-rv5j1201	882	41	condition	condition	NN
cord-022561-rv5j1201	882	42	results	result	NNS
cord-022561-rv5j1201	882	43	from	from	IN
cord-022561-rv5j1201	882	44	vitamin	vitamin	NN
cord-022561-rv5j1201	882	45	K	K	NNP
cord-022561-rv5j1201	882	46	deficiency	deficiency	NN
cord-022561-rv5j1201	882	47	.	.	.
cord-022561-rv5j1201	883	1	Conditions	condition	NNS
cord-022561-rv5j1201	883	2	with	with	IN
cord-022561-rv5j1201	884	1	avitaminosis	avitaminosis	NNP
cord-022561-rv5j1201	884	2	K	K	NNP
cord-022561-rv5j1201	884	3	include	include	VBP
cord-022561-rv5j1201	884	4	poisoning	poisoning	NN
cord-022561-rv5j1201	884	5	with	with	IN
cord-022561-rv5j1201	884	6	coumarin	coumarin	NN
cord-022561-rv5j1201	884	7	-	-	HYPH
cord-022561-rv5j1201	884	8	related	relate	VBN
cord-022561-rv5j1201	884	9	molecules	molecule	NNS
cord-022561-rv5j1201	884	10	,	,	,
cord-022561-rv5j1201	884	11	fat	fat	JJ
cord-022561-rv5j1201	884	12	malabsorption	malabsorption	NN
cord-022561-rv5j1201	884	13	(	(	-LRB-
cord-022561-rv5j1201	884	14	vitamin	vitamin	NN
cord-022561-rv5j1201	884	15	K	k	NN
cord-022561-rv5j1201	884	16	is	be	VBZ
cord-022561-rv5j1201	884	17	a	a	DT
cord-022561-rv5j1201	884	18	fat	fat	NN
cord-022561-rv5j1201	884	19	-	-	HYPH
cord-022561-rv5j1201	884	20	soluble	soluble	JJ
cord-022561-rv5j1201	884	21	vitamin	vitamin	NN
cord-022561-rv5j1201	884	22	)	)	-RRB-
cord-022561-rv5j1201	884	23	caused	cause	VBN
cord-022561-rv5j1201	884	24	by	by	IN
cord-022561-rv5j1201	884	25	primary	primary	JJ
cord-022561-rv5j1201	884	26	intestinal	intestinal	JJ
cord-022561-rv5j1201	884	27	disease	disease	NN
cord-022561-rv5j1201	884	28	or	or	CC
cord-022561-rv5j1201	884	29	impaired	impair	VBN
cord-022561-rv5j1201	884	30	biliary	biliary	JJ
cord-022561-rv5j1201	884	31	outflow	outflow	NN
cord-022561-rv5j1201	884	32	(	(	-LRB-
cord-022561-rv5j1201	884	33	uncommon	uncommon	JJ
cord-022561-rv5j1201	884	34	)	)	-RRB-
cord-022561-rv5j1201	884	35	,	,	,
cord-022561-rv5j1201	884	36	dietary	dietary	JJ
cord-022561-rv5j1201	884	37	deficiency	deficiency	NN
cord-022561-rv5j1201	884	38	(	(	-LRB-
cord-022561-rv5j1201	884	39	rare	rare	JJ
cord-022561-rv5j1201	884	40	)	)	-RRB-
cord-022561-rv5j1201	884	41	,	,	,
cord-022561-rv5j1201	884	42	and	and	CC
cord-022561-rv5j1201	884	43	antibiotics	antibiotic	NNS
cord-022561-rv5j1201	884	44	that	that	WDT
cord-022561-rv5j1201	884	45	interfere	interfere	VBP
cord-022561-rv5j1201	884	46	with	with	IN
cord-022561-rv5j1201	884	47	vitamin	vitamin	NN
cord-022561-rv5j1201	884	48	K	K	NNP
cord-022561-rv5j1201	884	49	absorption	absorption	NN
cord-022561-rv5j1201	884	50	or	or	CC
cord-022561-rv5j1201	884	51	usage	usage	NN
cord-022561-rv5j1201	884	52	.	.	.
cord-022561-rv5j1201	885	1	A	a	DT
cord-022561-rv5j1201	885	2	number	number	NN
cord-022561-rv5j1201	885	3	of	of	IN
cord-022561-rv5j1201	885	4	coagulation	coagulation	NN
cord-022561-rv5j1201	885	5	factors	factor	NNS
cord-022561-rv5j1201	885	6	-	-	,
cord-022561-rv5j1201	885	7	factors	factor	NNS
cord-022561-rv5j1201	885	8	II	II	NNP
cord-022561-rv5j1201	885	9	,	,	,
cord-022561-rv5j1201	885	10	VII	VII	NNP
cord-022561-rv5j1201	885	11	,	,	,
cord-022561-rv5j1201	885	12	IX	IX	NNP
cord-022561-rv5j1201	885	13	,	,	,
cord-022561-rv5j1201	885	14	and	and	CC
cord-022561-rv5j1201	885	15	X	X	NNP
cord-022561-rv5j1201	885	16	(	(	-LRB-
cord-022561-rv5j1201	885	17	collectively	collectively	RB
cord-022561-rv5j1201	885	18	known	know	VBN
cord-022561-rv5j1201	885	19	as	as	IN
cord-022561-rv5j1201	885	20	the	the	DT
cord-022561-rv5j1201	885	21	vitamin	vitamin	NN
cord-022561-rv5j1201	885	22	K	k	NN
cord-022561-rv5j1201	885	23	-	-	HYPH
cord-022561-rv5j1201	885	24	dependent	dependent	JJ
cord-022561-rv5j1201	885	25	factors	factor	NNS
cord-022561-rv5j1201	885	26	)	)	-RRB-
cord-022561-rv5j1201	885	27	,	,	,
cord-022561-rv5j1201	885	28	as	as	RB
cord-022561-rv5j1201	885	29	well	well	RB
cord-022561-rv5j1201	885	30	as	as	IN
cord-022561-rv5j1201	885	31	the	the	DT
cord-022561-rv5j1201	885	32	regulatory	regulatory	JJ
cord-022561-rv5j1201	885	33	molecules	molecule	NNS
cord-022561-rv5j1201	885	34	protein	protein	NN
cord-022561-rv5j1201	885	35	C	c	NN
cord-022561-rv5j1201	885	36	and	and	CC
cord-022561-rv5j1201	885	37	protein	protein	NN
cord-022561-rv5j1201	885	38	S	S	NNP
cord-022561-rv5j1201	885	39	-	-	:
cord-022561-rv5j1201	885	40	must	must	MD
cord-022561-rv5j1201	885	41	undergo	undergo	VB
cord-022561-rv5j1201	885	42	carboxylation	carboxylation	NN
cord-022561-rv5j1201	885	43	to	to	TO
cord-022561-rv5j1201	885	44	be	be	VB
cord-022561-rv5j1201	885	45	functional	functional	JJ
cord-022561-rv5j1201	885	46	.	.	.
cord-022561-rv5j1201	886	1	This	this	DT
cord-022561-rv5j1201	886	2	posttranslational	posttranslational	JJ
cord-022561-rv5j1201	886	3	modification	modification	NN
cord-022561-rv5j1201	886	4	is	be	VBZ
cord-022561-rv5j1201	886	5	catalyzed	catalyze	VBN
cord-022561-rv5j1201	886	6	by	by	IN
cord-022561-rv5j1201	886	7	the	the	DT
cord-022561-rv5j1201	886	8	enzyme	enzyme	NN
cord-022561-rv5j1201	886	9	γ	γ	NN
cord-022561-rv5j1201	886	10	-	-	HYPH
cord-022561-rv5j1201	886	11	glutamyl	glutamyl	NNP
cord-022561-rv5j1201	886	12	carboxylase	carboxylase	NNP
cord-022561-rv5j1201	886	13	,	,	,
cord-022561-rv5j1201	886	14	and	and	CC
cord-022561-rv5j1201	886	15	requires	require	VBZ
cord-022561-rv5j1201	886	16	vitamin	vitamin	NN
cord-022561-rv5j1201	886	17	K	K	NNP
cord-022561-rv5j1201	886	18	as	as	IN
cord-022561-rv5j1201	886	19	a	a	DT
cord-022561-rv5j1201	886	20	cofactor	cofactor	NN
cord-022561-rv5j1201	886	21	.	.	.
cord-022561-rv5j1201	887	1	Vitamin	vitamin	NN
cord-022561-rv5j1201	887	2	K	K	NNP
cord-022561-rv5j1201	887	3	is	be	VBZ
cord-022561-rv5j1201	887	4	oxidized	oxidize	VBN
cord-022561-rv5j1201	887	5	during	during	IN
cord-022561-rv5j1201	887	6	the	the	DT
cord-022561-rv5j1201	887	7	carboxylation	carboxylation	NN
cord-022561-rv5j1201	887	8	reaction	reaction	NN
cord-022561-rv5j1201	887	9	and	and	CC
cord-022561-rv5j1201	887	10	is	be	VBZ
cord-022561-rv5j1201	887	11	converted	convert	VBN
cord-022561-rv5j1201	887	12	back	back	RB
cord-022561-rv5j1201	887	13	into	into	IN
cord-022561-rv5j1201	887	14	its	-PRON-	PRP$
cord-022561-rv5j1201	887	15	active	active	JJ
cord-022561-rv5j1201	887	16	reduced	reduce	VBN
cord-022561-rv5j1201	887	17	form	form	NN
cord-022561-rv5j1201	887	18	by	by	IN
cord-022561-rv5j1201	887	19	the	the	DT
cord-022561-rv5j1201	887	20	enzyme	enzyme	NN
cord-022561-rv5j1201	887	21	vitamin	vitamin	NN
cord-022561-rv5j1201	887	22	K	K	NNP
cord-022561-rv5j1201	887	23	epoxide	epoxide	NN
cord-022561-rv5j1201	887	24	reductase	reductase	NN
cord-022561-rv5j1201	887	25	.	.	.
cord-022561-rv5j1201	888	1	Coumarin	coumarin	NN
cord-022561-rv5j1201	888	2	-	-	HYPH
cord-022561-rv5j1201	888	3	related	relate	VBN
cord-022561-rv5j1201	888	4	rodenticides	rodenticide	NNS
cord-022561-rv5j1201	888	5	,	,	,
cord-022561-rv5j1201	888	6	such	such	JJ
cord-022561-rv5j1201	888	7	as	as	IN
cord-022561-rv5j1201	888	8	warfarin	warfarin	NNP
cord-022561-rv5j1201	888	9	,	,	,
cord-022561-rv5j1201	888	10	act	act	VB
cord-022561-rv5j1201	888	11	by	by	IN
cord-022561-rv5j1201	888	12	inhibiting	inhibit	VBG
cord-022561-rv5j1201	888	13	vitamin	vitamin	NN
cord-022561-rv5j1201	888	14	K	k	NN
cord-022561-rv5j1201	888	15	epoxide	epoxide	NN
cord-022561-rv5j1201	888	16	reductase	reductase	NN
cord-022561-rv5j1201	888	17	,	,	,
cord-022561-rv5j1201	888	18	resulting	result	VBG
cord-022561-rv5j1201	888	19	in	in	IN
cord-022561-rv5j1201	888	20	an	an	DT
cord-022561-rv5j1201	888	21	absence	absence	NN
cord-022561-rv5j1201	888	22	of	of	IN
cord-022561-rv5j1201	888	23	vitamin	vitamin	NN
cord-022561-rv5j1201	888	24	K	k	NN
cord-022561-rv5j1201	888	25	in	in	IN
cord-022561-rv5j1201	888	26	its	-PRON-	PRP$
cord-022561-rv5j1201	888	27	active	active	JJ
cord-022561-rv5j1201	888	28	reduced	reduce	VBN
cord-022561-rv5j1201	888	29	form	form	NN
cord-022561-rv5j1201	888	30	(	(	-LRB-
cord-022561-rv5j1201	888	31	E-	E-	NNP
cord-022561-rv5j1201	888	32	Fig	Fig	NNP
cord-022561-rv5j1201	888	33	.	.	.
cord-022561-rv5j1201	888	34	13	13	CD
cord-022561-rv5j1201	888	35	-2	-2	CD
cord-022561-rv5j1201	888	36	)	)	-RRB-
cord-022561-rv5j1201	888	37	.	.	.
cord-022561-rv5j1201	889	1	This	this	DT
cord-022561-rv5j1201	889	2	inhibition	inhibition	NN
cord-022561-rv5j1201	889	3	lasts	last	VBZ
cord-022561-rv5j1201	889	4	until	until	IN
cord-022561-rv5j1201	889	5	the	the	DT
cord-022561-rv5j1201	889	6	rodenticide	rodenticide	NN
cord-022561-rv5j1201	889	7	is	be	VBZ
cord-022561-rv5j1201	889	8	metabolized	metabolize	VBN
cord-022561-rv5j1201	889	9	and	and	CC
cord-022561-rv5j1201	889	10	cleared	clear	VBN
cord-022561-rv5j1201	889	11	.	.	.
cord-022561-rv5j1201	890	1	How	how	WRB
cord-022561-rv5j1201	890	2	long	long	RB
cord-022561-rv5j1201	890	3	this	this	DT
cord-022561-rv5j1201	890	4	takes	take	VBZ
cord-022561-rv5j1201	890	5	depends	depend	VBZ
cord-022561-rv5j1201	890	6	on	on	IN
cord-022561-rv5j1201	890	7	the	the	DT
cord-022561-rv5j1201	890	8	half	half	JJ
cord-022561-rv5j1201	890	9	-	-	HYPH
cord-022561-rv5j1201	890	10	life	life	NN
cord-022561-rv5j1201	890	11	of	of	IN
cord-022561-rv5j1201	890	12	the	the	DT
cord-022561-rv5j1201	890	13	rodenticide	rodenticide	NN
cord-022561-rv5j1201	890	14	and	and	CC
cord-022561-rv5j1201	890	15	dose	dose	NN
cord-022561-rv5j1201	890	16	,	,	,
cord-022561-rv5j1201	890	17	but	but	CC
cord-022561-rv5j1201	890	18	it	-PRON-	PRP
cord-022561-rv5j1201	890	19	may	may	MD
cord-022561-rv5j1201	890	20	take	take	VB
cord-022561-rv5j1201	890	21	many	many	JJ
cord-022561-rv5j1201	890	22	weeks	week	NNS
cord-022561-rv5j1201	890	23	.	.	.
cord-022561-rv5j1201	891	1	Secondgeneration	secondgeneration	NN
cord-022561-rv5j1201	891	2	rodenticides	rodenticide	NNS
cord-022561-rv5j1201	891	3	,	,	,
cord-022561-rv5j1201	891	4	such	such	JJ
cord-022561-rv5j1201	891	5	as	as	IN
cord-022561-rv5j1201	891	6	bromadoline	bromadoline	NN
cord-022561-rv5j1201	891	7	and	and	CC
cord-022561-rv5j1201	891	8	brodifacoum	brodifacoum	NNP
cord-022561-rv5j1201	891	9	,	,	,
cord-022561-rv5j1201	891	10	are	be	VBP
cord-022561-rv5j1201	891	11	more	more	RBR
cord-022561-rv5j1201	891	12	potent	potent	JJ
cord-022561-rv5j1201	891	13	than	than	IN
cord-022561-rv5j1201	891	14	warfarin	warfarin	NN
cord-022561-rv5j1201	891	15	,	,	,
cord-022561-rv5j1201	891	16	with	with	IN
cord-022561-rv5j1201	891	17	longer	long	JJR
cord-022561-rv5j1201	891	18	half	half	RB
cord-022561-rv5j1201	891	19	-	-	HYPH
cord-022561-rv5j1201	891	20	lives	life	NNS
cord-022561-rv5j1201	891	21	.	.	.
cord-022561-rv5j1201	892	1	Spoiled	spoiled	JJ
cord-022561-rv5j1201	892	2	sweet	sweet	JJ
cord-022561-rv5j1201	892	3	clover	clover	NN
cord-022561-rv5j1201	892	4	contains	contain	VBZ
cord-022561-rv5j1201	892	5	dicumarol	dicumarol	NNP
cord-022561-rv5j1201	892	6	,	,	,
cord-022561-rv5j1201	892	7	which	which	WDT
cord-022561-rv5j1201	892	8	causes	cause	VBZ
cord-022561-rv5j1201	892	9	coagulopathy	coagulopathy	NN
cord-022561-rv5j1201	892	10	by	by	IN
cord-022561-rv5j1201	892	11	the	the	DT
cord-022561-rv5j1201	892	12	same	same	JJ
cord-022561-rv5j1201	892	13	mechanism	mechanism	NN
cord-022561-rv5j1201	892	14	.	.	.
cord-022561-rv5j1201	893	1	E-	E-	NNP
cord-022561-rv5j1201	893	2	Figure	figure	NN
cord-022561-rv5j1201	893	3	13	13	CD
cord-022561-rv5j1201	893	4	-2	-2	NNP
cord-022561-rv5j1201	893	5	Mechanism	Mechanism	NNP
cord-022561-rv5j1201	893	6	of	of	IN
cord-022561-rv5j1201	893	7	Anticoagulant	Anticoagulant	NNP
cord-022561-rv5j1201	893	8	Rodenticide	Rodenticide	NNP
cord-022561-rv5j1201	893	9	Toxicity	toxicity	NN
cord-022561-rv5j1201	893	10	.	.	.
cord-022561-rv5j1201	894	1	Anticoagulant	anticoagulant	NN
cord-022561-rv5j1201	894	2	rodenticides	rodenticide	NNS
cord-022561-rv5j1201	894	3	inhibit	inhibit	VBP
cord-022561-rv5j1201	894	4	the	the	DT
cord-022561-rv5j1201	894	5	enzyme	enzyme	NN
cord-022561-rv5j1201	894	6	that	that	WDT
cord-022561-rv5j1201	894	7	converts	convert	VBZ
cord-022561-rv5j1201	894	8	vitamin	vitamin	NN
cord-022561-rv5j1201	894	9	K	K	NNP
cord-022561-rv5j1201	894	10	back	back	RB
cord-022561-rv5j1201	894	11	to	to	IN
cord-022561-rv5j1201	894	12	its	-PRON-	PRP$
cord-022561-rv5j1201	894	13	active	active	JJ
cord-022561-rv5j1201	894	14	reduced	reduce	VBN
cord-022561-rv5j1201	894	15	form	form	NN
cord-022561-rv5j1201	894	16	.	.	.
cord-022561-rv5j1201	895	1	Active	active	JJ
cord-022561-rv5j1201	895	2	factors	factor	NNS
cord-022561-rv5j1201	895	3	(	(	-LRB-
cord-022561-rv5j1201	895	4	carboxylated	carboxylated	JJ
cord-022561-rv5j1201	895	5	)	)	-RRB-
cord-022561-rv5j1201	896	1	Inactive	inactive	JJ
cord-022561-rv5j1201	896	2	factors	factor	NNS
cord-022561-rv5j1201	896	3	(	(	-LRB-
cord-022561-rv5j1201	896	4	II	II	NNP
cord-022561-rv5j1201	896	5	,	,	,
cord-022561-rv5j1201	896	6	VII	VII	NNP
cord-022561-rv5j1201	896	7	,	,	,
cord-022561-rv5j1201	896	8	IX	IX	NNP
cord-022561-rv5j1201	896	9	,	,	,
cord-022561-rv5j1201	896	10	X	X	NNP
cord-022561-rv5j1201	896	11	)	)	-RRB-
cord-022561-rv5j1201	896	12	=	=	NFP
cord-022561-rv5j1201	897	1	Inactivation	inactivation	NN
cord-022561-rv5j1201	897	2	of	of	IN
cord-022561-rv5j1201	897	3	vitamin	vitamin	NN
cord-022561-rv5j1201	897	4	K	k	NN
cord-022561-rv5j1201	897	5	epoxide	epoxide	NN
cord-022561-rv5j1201	897	6	reductase	reductase	NN
cord-022561-rv5j1201	897	7	,	,	,
cord-022561-rv5j1201	897	8	the	the	DT
cord-022561-rv5j1201	897	9	enzyme	enzyme	NN
cord-022561-rv5j1201	897	10	that	that	WDT
cord-022561-rv5j1201	897	11	maintains	maintain	VBZ
cord-022561-rv5j1201	897	12	vitamin	vitamin	NN
cord-022561-rv5j1201	897	13	K	k	NN
cord-022561-rv5j1201	897	14	in	in	IN
cord-022561-rv5j1201	897	15	the	the	DT
cord-022561-rv5j1201	897	16	active	active	JJ
cord-022561-rv5j1201	897	17	form	form	NN
cord-022561-rv5j1201	897	18	Vitamin	vitamin	NN
cord-022561-rv5j1201	897	19	K	K	NNP
cord-022561-rv5j1201	897	20	epoxide	epoxide	NN
cord-022561-rv5j1201	897	21	(	(	-LRB-
cord-022561-rv5j1201	897	22	inactive	inactive	JJ
cord-022561-rv5j1201	897	23	)	)	-RRB-
cord-022561-rv5j1201	898	1	X	X	NNP
cord-022561-rv5j1201	898	2	X	X	NNP
cord-022561-rv5j1201	898	3	Laboratory	Laboratory	NNP
cord-022561-rv5j1201	898	4	findings	finding	NNS
cord-022561-rv5j1201	898	5	include	include	VBP
cord-022561-rv5j1201	898	6	prolonged	prolonged	JJ
cord-022561-rv5j1201	898	7	coagulation	coagulation	NN
cord-022561-rv5j1201	898	8	times	time	NNS
cord-022561-rv5j1201	898	9	(	(	-LRB-
cord-022561-rv5j1201	898	10	prothrombin	prothrombin	NN
cord-022561-rv5j1201	898	11	time	time	NN
cord-022561-rv5j1201	898	12	[	[	-LRB-
cord-022561-rv5j1201	898	13	PT	PT	NNP
cord-022561-rv5j1201	898	14	]	]	-RRB-
cord-022561-rv5j1201	898	15	,	,	,
cord-022561-rv5j1201	898	16	PTT	PTT	NNP
cord-022561-rv5j1201	898	17	,	,	,
cord-022561-rv5j1201	898	18	and	and	CC
cord-022561-rv5j1201	898	19	activated	activate	VBN
cord-022561-rv5j1201	898	20	clotting	clotting	NN
cord-022561-rv5j1201	898	21	time	time	NN
cord-022561-rv5j1201	898	22	[	[	-LRB-
cord-022561-rv5j1201	898	23	ACT	ACT	NNP
cord-022561-rv5j1201	898	24	]	]	-RRB-
cord-022561-rv5j1201	898	25	)	)	-RRB-
cord-022561-rv5j1201	898	26	.	.	.
cord-022561-rv5j1201	899	1	Early	early	RB
cord-022561-rv5j1201	899	2	in	in	IN
cord-022561-rv5j1201	899	3	the	the	DT
cord-022561-rv5j1201	899	4	course	course	NN
cord-022561-rv5j1201	899	5	of	of	IN
cord-022561-rv5j1201	899	6	rodenticide	rodenticide	NN
cord-022561-rv5j1201	899	7	and	and	CC
cord-022561-rv5j1201	899	8	related	relate	VBN
cord-022561-rv5j1201	899	9	toxicoses	toxicose	NNS
cord-022561-rv5j1201	899	10	,	,	,
cord-022561-rv5j1201	899	11	PT	PT	NNP
cord-022561-rv5j1201	899	12	may	may	MD
cord-022561-rv5j1201	899	13	be	be	VB
cord-022561-rv5j1201	899	14	the	the	DT
cord-022561-rv5j1201	899	15	only	only	JJ
cord-022561-rv5j1201	899	16	one	one	CD
cord-022561-rv5j1201	899	17	of	of	IN
cord-022561-rv5j1201	899	18	these	these	DT
cord-022561-rv5j1201	899	19	tests	test	NNS
cord-022561-rv5j1201	899	20	that	that	WDT
cord-022561-rv5j1201	899	21	is	be	VBZ
cord-022561-rv5j1201	899	22	prolonged	prolong	VBN
cord-022561-rv5j1201	899	23	because	because	IN
cord-022561-rv5j1201	899	24	factor	factor	NN
cord-022561-rv5j1201	899	25	VII	VII	NNP
cord-022561-rv5j1201	899	26	has	have	VBZ
cord-022561-rv5j1201	899	27	the	the	DT
cord-022561-rv5j1201	899	28	shortest	short	JJS
cord-022561-rv5j1201	899	29	half	half	JJ
cord-022561-rv5j1201	899	30	-	-	HYPH
cord-022561-rv5j1201	899	31	life	life	NN
cord-022561-rv5j1201	899	32	of	of	IN
cord-022561-rv5j1201	899	33	the	the	DT
cord-022561-rv5j1201	899	34	vitamin	vitamin	NN
cord-022561-rv5j1201	899	35	K	k	NN
cord-022561-rv5j1201	899	36	-	-	HYPH
cord-022561-rv5j1201	899	37	dependent	dependent	JJ
cord-022561-rv5j1201	899	38	factors	factor	NNS
cord-022561-rv5j1201	899	39	.	.	.
cord-022561-rv5j1201	900	1	However	however	RB
cord-022561-rv5j1201	900	2	,	,	,
cord-022561-rv5j1201	900	3	the	the	DT
cord-022561-rv5j1201	900	4	other	other	JJ
cord-022561-rv5j1201	900	5	tests	test	NNS
cord-022561-rv5j1201	900	6	become	become	VBP
cord-022561-rv5j1201	900	7	prolonged	prolonged	JJ
cord-022561-rv5j1201	900	8	as	as	IN
cord-022561-rv5j1201	900	9	nonfunctional	nonfunctional	JJ
cord-022561-rv5j1201	900	10	forms	form	NNS
cord-022561-rv5j1201	900	11	of	of	IN
cord-022561-rv5j1201	900	12	the	the	DT
cord-022561-rv5j1201	900	13	other	other	JJ
cord-022561-rv5j1201	900	14	factors	factor	NNS
cord-022561-rv5j1201	900	15	accumulate	accumulate	VBP
cord-022561-rv5j1201	900	16	.	.	.
cord-022561-rv5j1201	901	1	In	in	IN
cord-022561-rv5j1201	901	2	uncomplicated	uncomplicated	JJ
cord-022561-rv5j1201	901	3	cases	case	NNS
cord-022561-rv5j1201	901	4	,	,	,
cord-022561-rv5j1201	901	5	patients	patient	NNS
cord-022561-rv5j1201	901	6	are	be	VBP
cord-022561-rv5j1201	901	7	not	not	RB
cord-022561-rv5j1201	901	8	thrombocytopenic	thrombocytopenic	JJ
cord-022561-rv5j1201	901	9	.	.	.
cord-022561-rv5j1201	902	1	A	a	DT
cord-022561-rv5j1201	902	2	wide	wide	JJ
cord-022561-rv5j1201	902	3	range	range	NN
cord-022561-rv5j1201	902	4	of	of	IN
cord-022561-rv5j1201	902	5	hemorrhagic	hemorrhagic	JJ
cord-022561-rv5j1201	902	6	lesions	lesion	NNS
cord-022561-rv5j1201	902	7	may	may	MD
cord-022561-rv5j1201	902	8	occur	occur	VB
cord-022561-rv5j1201	902	9	in	in	IN
cord-022561-rv5j1201	902	10	affected	affect	VBN
cord-022561-rv5j1201	902	11	individuals	individual	NNS
cord-022561-rv5j1201	902	12	,	,	,
cord-022561-rv5j1201	902	13	including	include	VBG
cord-022561-rv5j1201	902	14	ecchymoses	ecchymosis	NNS
cord-022561-rv5j1201	902	15	,	,	,
cord-022561-rv5j1201	902	16	epistaxis	epistaxis	NN
cord-022561-rv5j1201	902	17	,	,	,
cord-022561-rv5j1201	902	18	gingival	gingival	NN
cord-022561-rv5j1201	902	19	bleeding	bleeding	NN
cord-022561-rv5j1201	902	20	,	,	,
cord-022561-rv5j1201	902	21	hematomas	hematoma	NNS
cord-022561-rv5j1201	902	22	,	,	,
cord-022561-rv5j1201	902	23	hemoptysis	hemoptysis	NN
cord-022561-rv5j1201	902	24	,	,	,
cord-022561-rv5j1201	902	25	melena	melena	NNP
cord-022561-rv5j1201	902	26	or	or	CC
cord-022561-rv5j1201	902	27	hematochezia	hematochezia	NNP
cord-022561-rv5j1201	902	28	,	,	,
cord-022561-rv5j1201	902	29	hematuria	hematuria	NN
cord-022561-rv5j1201	902	30	,	,	,
cord-022561-rv5j1201	902	31	and	and	CC
cord-022561-rv5j1201	902	32	other	other	JJ
cord-022561-rv5j1201	902	33	forms	form	NNS
cord-022561-rv5j1201	902	34	of	of	IN
cord-022561-rv5j1201	902	35	hemorrhage	hemorrhage	NN
cord-022561-rv5j1201	902	36	.	.	.
cord-022561-rv5j1201	903	1	There	there	EX
cord-022561-rv5j1201	903	2	are	be	VBP
cord-022561-rv5j1201	903	3	also	also	RB
cord-022561-rv5j1201	903	4	lesions	lesion	NNS
cord-022561-rv5j1201	903	5	with	with	IN
cord-022561-rv5j1201	903	6	regenerative	regenerative	JJ
cord-022561-rv5j1201	903	7	anemia	anemia	NN
cord-022561-rv5j1201	903	8	,	,	,
cord-022561-rv5j1201	903	9	such	such	JJ
cord-022561-rv5j1201	903	10	as	as	IN
cord-022561-rv5j1201	903	11	pale	pale	JJ
cord-022561-rv5j1201	903	12	mucous	mucous	JJ
cord-022561-rv5j1201	903	13	membranes	membrane	NNS
cord-022561-rv5j1201	903	14	and	and	CC
cord-022561-rv5j1201	903	15	splenomegaly	splenomegaly	NN
cord-022561-rv5j1201	903	16	.	.	.
cord-022561-rv5j1201	904	1	Histologically	histologically	RB
cord-022561-rv5j1201	904	2	,	,	,
cord-022561-rv5j1201	904	3	there	there	EX
cord-022561-rv5j1201	904	4	is	be	VBZ
cord-022561-rv5j1201	904	5	hemorrhage	hemorrhage	NN
cord-022561-rv5j1201	904	6	,	,	,
cord-022561-rv5j1201	904	7	EMH	EMH	NNP
cord-022561-rv5j1201	904	8	,	,	,
cord-022561-rv5j1201	904	9	and	and	CC
cord-022561-rv5j1201	904	10	marrow	marrow	NN
cord-022561-rv5j1201	904	11	erythroid	erythroid	NN
cord-022561-rv5j1201	904	12	hyperplasia	hyperplasia	NN
cord-022561-rv5j1201	904	13	.	.	.
cord-022561-rv5j1201	905	1	The	the	DT
cord-022561-rv5j1201	905	2	treatment	treatment	NN
cord-022561-rv5j1201	905	3	of	of	IN
cord-022561-rv5j1201	905	4	cases	case	NNS
cord-022561-rv5j1201	905	5	of	of	IN
cord-022561-rv5j1201	905	6	rodenticide	rodenticide	NN
cord-022561-rv5j1201	905	7	and	and	CC
cord-022561-rv5j1201	905	8	related	related	JJ
cord-022561-rv5j1201	905	9	toxicoses	toxicose	NNS
cord-022561-rv5j1201	905	10	is	be	VBZ
cord-022561-rv5j1201	905	11	regular	regular	JJ
cord-022561-rv5j1201	905	12	administration	administration	NN
cord-022561-rv5j1201	905	13	of	of	IN
cord-022561-rv5j1201	905	14	exogenous	exogenous	JJ
cord-022561-rv5j1201	905	15	vitamin	vitamin	NN
cord-022561-rv5j1201	905	16	K	K	NNP
cord-022561-rv5j1201	905	17	1	1	CD
cord-022561-rv5j1201	905	18	until	until	IN
cord-022561-rv5j1201	905	19	the	the	DT
cord-022561-rv5j1201	905	20	toxin	toxin	NN
cord-022561-rv5j1201	905	21	is	be	VBZ
cord-022561-rv5j1201	905	22	cleared	clear	VBN
cord-022561-rv5j1201	905	23	(	(	-LRB-
cord-022561-rv5j1201	905	24	determined	determine	VBN
cord-022561-rv5j1201	905	25	by	by	IN
cord-022561-rv5j1201	905	26	repeat	repeat	NN
cord-022561-rv5j1201	905	27	coagulation	coagulation	NN
cord-022561-rv5j1201	905	28	testing	testing	NN
cord-022561-rv5j1201	905	29	after	after	IN
cord-022561-rv5j1201	905	30	withholding	withhold	VBG
cord-022561-rv5j1201	905	31	treatment	treatment	NN
cord-022561-rv5j1201	905	32	)	)	-RRB-
cord-022561-rv5j1201	905	33	.	.	.
cord-022561-rv5j1201	906	1	Babesiosis	babesiosis	NN
cord-022561-rv5j1201	906	2	may	may	MD
cord-022561-rv5j1201	906	3	cause	cause	VB
cord-022561-rv5j1201	906	4	intravascular	intravascular	JJ
cord-022561-rv5j1201	906	5	and	and	CC
cord-022561-rv5j1201	906	6	extravascular	extravascular	JJ
cord-022561-rv5j1201	906	7	hemolytic	hemolytic	JJ
cord-022561-rv5j1201	906	8	anemia	anemia	NN
cord-022561-rv5j1201	906	9	via	via	IN
cord-022561-rv5j1201	906	10	direct	direct	JJ
cord-022561-rv5j1201	906	11	red	red	JJ
cord-022561-rv5j1201	906	12	blood	blood	NN
cord-022561-rv5j1201	906	13	cell	cell	NN
cord-022561-rv5j1201	906	14	injury	injury	NN
cord-022561-rv5j1201	906	15	,	,	,
cord-022561-rv5j1201	906	16	the	the	DT
cord-022561-rv5j1201	906	17	innocent	innocent	JJ
cord-022561-rv5j1201	906	18	bystander	bystander	NN
cord-022561-rv5j1201	906	19	effect	effect	NN
cord-022561-rv5j1201	906	20	,	,	,
cord-022561-rv5j1201	906	21	and	and	CC
cord-022561-rv5j1201	906	22	secondary	secondary	JJ
cord-022561-rv5j1201	906	23	immune	immune	NN
cord-022561-rv5j1201	906	24	-	-	HYPH
cord-022561-rv5j1201	906	25	mediated	mediate	VBN
cord-022561-rv5j1201	906	26	hemolytic	hemolytic	JJ
cord-022561-rv5j1201	906	27	anemia	anemia	NN
cord-022561-rv5j1201	906	28	.	.	.
cord-022561-rv5j1201	907	1	Infection	infection	NN
cord-022561-rv5j1201	907	2	with	with	IN
cord-022561-rv5j1201	907	3	highly	highly	RB
cord-022561-rv5j1201	907	4	virulent	virulent	JJ
cord-022561-rv5j1201	907	5	strains	strain	NNS
cord-022561-rv5j1201	907	6	may	may	MD
cord-022561-rv5j1201	907	7	cause	cause	VB
cord-022561-rv5j1201	907	8	severe	severe	JJ
cord-022561-rv5j1201	907	9	multisystemic	multisystemic	JJ
cord-022561-rv5j1201	907	10	disease	disease	NN
cord-022561-rv5j1201	907	11	.	.	.
cord-022561-rv5j1201	908	1	In	in	IN
cord-022561-rv5j1201	908	2	these	these	DT
cord-022561-rv5j1201	908	3	cases	case	NNS
cord-022561-rv5j1201	908	4	,	,	,
cord-022561-rv5j1201	908	5	massive	massive	JJ
cord-022561-rv5j1201	908	6	immunostimulation	immunostimulation	NN
cord-022561-rv5j1201	908	7	and	and	CC
cord-022561-rv5j1201	908	8	cytokine	cytokine	NN
cord-022561-rv5j1201	908	9	release	release	NN
cord-022561-rv5j1201	908	10	cause	cause	IN
cord-022561-rv5j1201	908	11	circulatory	circulatory	JJ
cord-022561-rv5j1201	908	12	disturbances	disturbance	NNS
cord-022561-rv5j1201	908	13	,	,	,
cord-022561-rv5j1201	908	14	which	which	WDT
cord-022561-rv5j1201	908	15	may	may	MD
cord-022561-rv5j1201	908	16	result	result	VB
cord-022561-rv5j1201	908	17	in	in	IN
cord-022561-rv5j1201	908	18	shock	shock	NN
cord-022561-rv5j1201	908	19	,	,	,
cord-022561-rv5j1201	908	20	induction	induction	NN
cord-022561-rv5j1201	908	21	of	of	IN
cord-022561-rv5j1201	908	22	the	the	DT
cord-022561-rv5j1201	908	23	systemic	systemic	JJ
cord-022561-rv5j1201	908	24	inflammatory	inflammatory	JJ
cord-022561-rv5j1201	908	25	response	response	NN
cord-022561-rv5j1201	908	26	,	,	,
cord-022561-rv5j1201	908	27	and	and	CC
cord-022561-rv5j1201	908	28	multiple	multiple	JJ
cord-022561-rv5j1201	908	29	organ	organ	NN
cord-022561-rv5j1201	908	30	dysfunction	dysfunction	NN
cord-022561-rv5j1201	908	31	syndromes	syndrome	NNS
cord-022561-rv5j1201	908	32	.	.	.
cord-022561-rv5j1201	909	1	Babesia	babesia	JJ
cord-022561-rv5j1201	909	2	organisms	organism	NNS
cord-022561-rv5j1201	909	3	can	can	MD
cord-022561-rv5j1201	909	4	usually	usually	RB
cord-022561-rv5j1201	909	5	be	be	VB
cord-022561-rv5j1201	909	6	detected	detect	VBN
cord-022561-rv5j1201	909	7	on	on	IN
cord-022561-rv5j1201	909	8	a	a	DT
cord-022561-rv5j1201	909	9	routine	routine	JJ
cord-022561-rv5j1201	909	10	blood	blood	NN
cord-022561-rv5j1201	909	11	smear	smear	NN
cord-022561-rv5j1201	909	12	in	in	IN
cord-022561-rv5j1201	909	13	animals	animal	NNS
cord-022561-rv5j1201	909	14	with	with	IN
cord-022561-rv5j1201	909	15	acute	acute	JJ
cord-022561-rv5j1201	909	16	disease	disease	NN
cord-022561-rv5j1201	909	17	.	.	.
cord-022561-rv5j1201	910	1	Infected	infected	JJ
cord-022561-rv5j1201	910	2	erythrocytes	erythrocyte	NNS
cord-022561-rv5j1201	910	3	may	may	MD
cord-022561-rv5j1201	910	4	be	be	VB
cord-022561-rv5j1201	910	5	more	more	RBR
cord-022561-rv5j1201	910	6	prevalent	prevalent	JJ
cord-022561-rv5j1201	910	7	in	in	IN
cord-022561-rv5j1201	910	8	capillary	capillary	JJ
cord-022561-rv5j1201	910	9	blood	blood	NN
cord-022561-rv5j1201	910	10	,	,	,
cord-022561-rv5j1201	910	11	so	so	RB
cord-022561-rv5j1201	910	12	blood	blood	NN
cord-022561-rv5j1201	910	13	smears	smear	NNS
cord-022561-rv5j1201	910	14	made	make	VBN
cord-022561-rv5j1201	910	15	from	from	IN
cord-022561-rv5j1201	910	16	samples	sample	NNS
cord-022561-rv5j1201	910	17	taken	take	VBN
cord-022561-rv5j1201	910	18	from	from	IN
cord-022561-rv5j1201	910	19	the	the	DT
cord-022561-rv5j1201	910	20	pinna	pinna	NN
cord-022561-rv5j1201	910	21	of	of	IN
cord-022561-rv5j1201	910	22	the	the	DT
cord-022561-rv5j1201	910	23	ear	ear	NN
cord-022561-rv5j1201	910	24	or	or	CC
cord-022561-rv5j1201	910	25	the	the	DT
cord-022561-rv5j1201	910	26	nail	nail	NN
cord-022561-rv5j1201	910	27	bed	bed	NN
cord-022561-rv5j1201	910	28	may	may	MD
cord-022561-rv5j1201	910	29	increase	increase	VB
cord-022561-rv5j1201	910	30	the	the	DT
cord-022561-rv5j1201	910	31	likelihood	likelihood	NN
cord-022561-rv5j1201	910	32	of	of	IN
cord-022561-rv5j1201	910	33	detecting	detect	VBG
cord-022561-rv5j1201	910	34	organisms	organism	NNS
cord-022561-rv5j1201	910	35	microscopically	microscopically	RB
cord-022561-rv5j1201	910	36	.	.	.
cord-022561-rv5j1201	911	1	Buffy	Buffy	NNP
cord-022561-rv5j1201	911	2	coat	coat	NN
cord-022561-rv5j1201	911	3	smears	smear	VBZ
cord-022561-rv5j1201	911	4	also	also	RB
cord-022561-rv5j1201	911	5	have	have	VBP
cord-022561-rv5j1201	911	6	an	an	DT
cord-022561-rv5j1201	911	7	enriched	enriched	JJ
cord-022561-rv5j1201	911	8	population	population	NN
cord-022561-rv5j1201	911	9	of	of	IN
cord-022561-rv5j1201	911	10	infected	infected	JJ
cord-022561-rv5j1201	911	11	erythrocytes	erythrocyte	NNS
cord-022561-rv5j1201	911	12	.	.	.
cord-022561-rv5j1201	912	1	PCR	PCR	NNP
cord-022561-rv5j1201	912	2	-	-	HYPH
cord-022561-rv5j1201	912	3	based	base	VBN
cord-022561-rv5j1201	912	4	tests	test	NNS
cord-022561-rv5j1201	912	5	are	be	VBP
cord-022561-rv5j1201	912	6	the	the	DT
cord-022561-rv5j1201	912	7	most	most	RBS
cord-022561-rv5j1201	912	8	sensitive	sensitive	JJ
cord-022561-rv5j1201	912	9	assay	assay	NN
cord-022561-rv5j1201	912	10	for	for	IN
cord-022561-rv5j1201	912	11	detecting	detect	VBG
cord-022561-rv5j1201	912	12	infection	infection	NN
cord-022561-rv5j1201	912	13	in	in	IN
cord-022561-rv5j1201	912	14	animals	animal	NNS
cord-022561-rv5j1201	912	15	with	with	IN
cord-022561-rv5j1201	912	16	very	very	RB
cord-022561-rv5j1201	912	17	low	low	JJ
cord-022561-rv5j1201	912	18	levels	level	NNS
cord-022561-rv5j1201	912	19	of	of	IN
cord-022561-rv5j1201	912	20	parasitemia	parasitemia	NN
cord-022561-rv5j1201	912	21	.	.	.
cord-022561-rv5j1201	913	1	At	at	IN
cord-022561-rv5j1201	913	2	necropsy	necropsy	JJ
cord-022561-rv5j1201	913	3	,	,	,
cord-022561-rv5j1201	913	4	gross	gross	JJ
cord-022561-rv5j1201	913	5	lesions	lesion	NNS
cord-022561-rv5j1201	913	6	are	be	VBP
cord-022561-rv5j1201	913	7	mainly	mainly	RB
cord-022561-rv5j1201	913	8	related	relate	VBN
cord-022561-rv5j1201	913	9	to	to	IN
cord-022561-rv5j1201	913	10	hemolysis	hemolysis	NN
cord-022561-rv5j1201	913	11	and	and	CC
cord-022561-rv5j1201	913	12	include	include	VBP
cord-022561-rv5j1201	913	13	pale	pale	JJ
cord-022561-rv5j1201	913	14	mucous	mucous	JJ
cord-022561-rv5j1201	913	15	membranes	membrane	NNS
cord-022561-rv5j1201	913	16	,	,	,
cord-022561-rv5j1201	913	17	icterus	icterus	NN
cord-022561-rv5j1201	913	18	,	,	,
cord-022561-rv5j1201	913	19	splenomegaly	splenomegaly	NN
cord-022561-rv5j1201	913	20	,	,	,
cord-022561-rv5j1201	913	21	dark	dark	JJ
cord-022561-rv5j1201	913	22	red	red	JJ
cord-022561-rv5j1201	913	23	or	or	CC
cord-022561-rv5j1201	913	24	black	black	JJ
cord-022561-rv5j1201	913	25	kidneys	kidney	NNS
cord-022561-rv5j1201	913	26	,	,	,
cord-022561-rv5j1201	913	27	and	and	CC
cord-022561-rv5j1201	913	28	reddish	reddish	JJ
cord-022561-rv5j1201	913	29	-	-	HYPH
cord-022561-rv5j1201	913	30	brown	brown	JJ
cord-022561-rv5j1201	913	31	urine	urine	NN
cord-022561-rv5j1201	913	32	.	.	.
cord-022561-rv5j1201	914	1	The	the	DT
cord-022561-rv5j1201	914	2	cut	cut	NN
cord-022561-rv5j1201	914	3	surface	surface	NN
cord-022561-rv5j1201	914	4	of	of	IN
cord-022561-rv5j1201	914	5	the	the	DT
cord-022561-rv5j1201	914	6	congested	congested	JJ
cord-022561-rv5j1201	914	7	spleen	spleen	NN
cord-022561-rv5j1201	914	8	oozes	ooze	VBZ
cord-022561-rv5j1201	914	9	blood	blood	NN
cord-022561-rv5j1201	914	10	.	.	.
cord-022561-rv5j1201	915	1	The	the	DT
cord-022561-rv5j1201	915	2	gallbladder	gallbladder	NN
cord-022561-rv5j1201	915	3	is	be	VBZ
cord-022561-rv5j1201	915	4	usually	usually	RB
cord-022561-rv5j1201	915	5	distended	distend	VBN
cord-022561-rv5j1201	915	6	with	with	IN
cord-022561-rv5j1201	915	7	thick	thick	JJ
cord-022561-rv5j1201	915	8	bile	bile	NN
cord-022561-rv5j1201	915	9	.	.	.
cord-022561-rv5j1201	916	1	Less	less	RBR
cord-022561-rv5j1201	916	2	common	common	JJ
cord-022561-rv5j1201	916	3	lesions	lesion	NNS
cord-022561-rv5j1201	916	4	include	include	VBP
cord-022561-rv5j1201	916	5	pulmonary	pulmonary	JJ
cord-022561-rv5j1201	916	6	edema	edema	NN
cord-022561-rv5j1201	916	7	,	,	,
cord-022561-rv5j1201	916	8	ascites	ascites	NN
cord-022561-rv5j1201	916	9	,	,	,
cord-022561-rv5j1201	916	10	and	and	CC
cord-022561-rv5j1201	916	11	congestion	congestion	NN
cord-022561-rv5j1201	916	12	,	,	,
cord-022561-rv5j1201	916	13	petechiae	petechia	NNS
cord-022561-rv5j1201	916	14	,	,	,
cord-022561-rv5j1201	916	15	and	and	CC
cord-022561-rv5j1201	916	16	ecchymoses	ecchymosis	NNS
cord-022561-rv5j1201	916	17	of	of	IN
cord-022561-rv5j1201	916	18	organs	organ	NNS
cord-022561-rv5j1201	916	19	,	,	,
cord-022561-rv5j1201	916	20	including	include	VBG
cord-022561-rv5j1201	916	21	the	the	DT
cord-022561-rv5j1201	916	22	heart	heart	NN
cord-022561-rv5j1201	916	23	and	and	CC
cord-022561-rv5j1201	916	24	brain	brain	NN
cord-022561-rv5j1201	916	25	.	.	.
cord-022561-rv5j1201	917	1	Parasitized	parasitized	JJ
cord-022561-rv5j1201	917	2	erythrocytes	erythrocyte	NNS
cord-022561-rv5j1201	917	3	are	be	VBP
cord-022561-rv5j1201	917	4	best	well	RBS
cord-022561-rv5j1201	917	5	visualized	visualize	VBN
cord-022561-rv5j1201	917	6	on	on	IN
cord-022561-rv5j1201	917	7	impression	impression	NN
cord-022561-rv5j1201	917	8	smears	smear	NNS
cord-022561-rv5j1201	917	9	of	of	IN
cord-022561-rv5j1201	917	10	the	the	DT
cord-022561-rv5j1201	917	11	kidney	kidney	NN
cord-022561-rv5j1201	917	12	,	,	,
cord-022561-rv5j1201	917	13	brain	brain	NN
cord-022561-rv5j1201	917	14	,	,	,
cord-022561-rv5j1201	917	15	and	and	CC
cord-022561-rv5j1201	917	16	skeletal	skeletal	JJ
cord-022561-rv5j1201	917	17	muscle	muscle	NN
cord-022561-rv5j1201	917	18	.	.	.
cord-022561-rv5j1201	918	1	Microscopic	microscopic	JJ
cord-022561-rv5j1201	918	2	findings	finding	NNS
cord-022561-rv5j1201	918	3	in	in	IN
cord-022561-rv5j1201	918	4	the	the	DT
cord-022561-rv5j1201	918	5	liver	liver	NN
cord-022561-rv5j1201	918	6	and	and	CC
cord-022561-rv5j1201	918	7	kidney	kidney	NN
cord-022561-rv5j1201	918	8	are	be	VBP
cord-022561-rv5j1201	918	9	typical	typical	JJ
cord-022561-rv5j1201	918	10	of	of	IN
cord-022561-rv5j1201	918	11	a	a	DT
cord-022561-rv5j1201	918	12	hemolytic	hemolytic	JJ
cord-022561-rv5j1201	918	13	crisis	crisis	NN
cord-022561-rv5j1201	918	14	and	and	CC
cord-022561-rv5j1201	918	15	include	include	VBP
cord-022561-rv5j1201	918	16	anemia	anemia	NN
cord-022561-rv5j1201	918	17	-	-	HYPH
cord-022561-rv5j1201	918	18	induced	induce	VBN
cord-022561-rv5j1201	918	19	degeneration	degeneration	NN
cord-022561-rv5j1201	918	20	,	,	,
cord-022561-rv5j1201	918	21	necrosis	necrosis	NN
cord-022561-rv5j1201	918	22	of	of	IN
cord-022561-rv5j1201	918	23	periacinar	periacinar	JJ
cord-022561-rv5j1201	918	24	hepatocytes	hepatocyte	NNS
cord-022561-rv5j1201	918	25	and	and	CC
cord-022561-rv5j1201	918	26	cholestasis	cholestasis	NN
cord-022561-rv5j1201	918	27	,	,	,
cord-022561-rv5j1201	918	28	and	and	CC
cord-022561-rv5j1201	918	29	hemoglobinuric	hemoglobinuric	NNP
cord-022561-rv5j1201	918	30	nephrosis	nephrosis	NNP
cord-022561-rv5j1201	918	31	with	with	IN
cord-022561-rv5j1201	918	32	degeneration	degeneration	NN
cord-022561-rv5j1201	918	33	of	of	IN
cord-022561-rv5j1201	918	34	tubular	tubular	JJ
cord-022561-rv5j1201	918	35	epithelium	epithelium	NN
cord-022561-rv5j1201	918	36	.	.	.
cord-022561-rv5j1201	919	1	Erythroid	Erythroid	NNP
cord-022561-rv5j1201	919	2	hyperplasia	hyperplasia	NN
cord-022561-rv5j1201	919	3	is	be	VBZ
cord-022561-rv5j1201	919	4	present	present	JJ
cord-022561-rv5j1201	919	5	in	in	IN
cord-022561-rv5j1201	919	6	the	the	DT
cord-022561-rv5j1201	919	7	bone	bone	NN
cord-022561-rv5j1201	919	8	marrow	marrow	NN
cord-022561-rv5j1201	919	9	.	.	.
cord-022561-rv5j1201	920	1	In	in	IN
cord-022561-rv5j1201	920	2	animals	animal	NNS
cord-022561-rv5j1201	920	3	that	that	WDT
cord-022561-rv5j1201	920	4	survive	survive	VBP
cord-022561-rv5j1201	920	5	the	the	DT
cord-022561-rv5j1201	920	6	acute	acute	JJ
cord-022561-rv5j1201	920	7	disease	disease	NN
cord-022561-rv5j1201	920	8	,	,	,
cord-022561-rv5j1201	920	9	there	there	EX
cord-022561-rv5j1201	920	10	is	be	VBZ
cord-022561-rv5j1201	920	11	hemosiderin	hemosiderin	NNP
cord-022561-rv5j1201	920	12	accumulation	accumulation	NN
cord-022561-rv5j1201	920	13	in	in	IN
cord-022561-rv5j1201	920	14	the	the	DT
cord-022561-rv5j1201	920	15	liver	liver	NN
cord-022561-rv5j1201	920	16	,	,	,
cord-022561-rv5j1201	920	17	kidney	kidney	NN
cord-022561-rv5j1201	920	18	,	,	,
cord-022561-rv5j1201	920	19	spleen	spleen	NNS
cord-022561-rv5j1201	920	20	,	,	,
cord-022561-rv5j1201	920	21	and	and	CC
cord-022561-rv5j1201	920	22	bone	bone	NN
cord-022561-rv5j1201	920	23	marrow	marrow	NN
cord-022561-rv5j1201	920	24	.	.	.
cord-022561-rv5j1201	921	1	In	in	IN
cord-022561-rv5j1201	921	2	chronic	chronic	JJ
cord-022561-rv5j1201	921	3	cases	case	NNS
cord-022561-rv5j1201	921	4	there	there	EX
cord-022561-rv5j1201	921	5	is	be	VBZ
cord-022561-rv5j1201	921	6	hyperplasia	hyperplasia	NN
cord-022561-rv5j1201	921	7	of	of	IN
cord-022561-rv5j1201	921	8	macrophages	macrophage	NNS
cord-022561-rv5j1201	921	9	in	in	IN
cord-022561-rv5j1201	921	10	the	the	DT
cord-022561-rv5j1201	921	11	red	red	JJ
cord-022561-rv5j1201	921	12	pulp	pulp	NN
cord-022561-rv5j1201	921	13	of	of	IN
cord-022561-rv5j1201	921	14	the	the	DT
cord-022561-rv5j1201	921	15	spleen	spleen	NN
cord-022561-rv5j1201	921	16	.	.	.
cord-022561-rv5j1201	922	1	Theileriosis	Theileriosis	NNP
cord-022561-rv5j1201	922	2	(	(	-LRB-
cord-022561-rv5j1201	922	3	Piroplasmosis	Piroplasmosis	NNP
cord-022561-rv5j1201	922	4	)	)	-RRB-
cord-022561-rv5j1201	922	5	.	.	.
cord-022561-rv5j1201	923	1	Theileria	Theileria	NNP
cord-022561-rv5j1201	923	2	spp	spp	NNS
cord-022561-rv5j1201	923	3	.	.	.
cord-022561-rv5j1201	924	1	are	be	VBP
cord-022561-rv5j1201	924	2	tick	tick	NN
cord-022561-rv5j1201	924	3	-	-	HYPH
cord-022561-rv5j1201	924	4	borne	bear	VBN
cord-022561-rv5j1201	924	5	protozoal	protozoal	NN
cord-022561-rv5j1201	924	6	organisms	organism	NNS
cord-022561-rv5j1201	924	7	that	that	WDT
cord-022561-rv5j1201	924	8	infect	infect	VBP
cord-022561-rv5j1201	924	9	many	many	JJ
cord-022561-rv5j1201	924	10	domestic	domestic	JJ
cord-022561-rv5j1201	924	11	and	and	CC
cord-022561-rv5j1201	924	12	wild	wild	JJ
cord-022561-rv5j1201	924	13	animals	animal	NNS
cord-022561-rv5j1201	924	14	worldwide	worldwide	RB
cord-022561-rv5j1201	924	15	.	.	.
cord-022561-rv5j1201	925	1	Numerous	numerous	JJ
cord-022561-rv5j1201	925	2	Theileria	Theileria	NNP
cord-022561-rv5j1201	925	3	spp	spp	NNS
cord-022561-rv5j1201	925	4	.	.	.
cord-022561-rv5j1201	926	1	have	have	VBP
cord-022561-rv5j1201	926	2	been	be	VBN
cord-022561-rv5j1201	926	3	documented	document	VBN
cord-022561-rv5j1201	926	4	,	,	,
cord-022561-rv5j1201	926	5	but	but	CC
cord-022561-rv5j1201	926	6	only	only	RB
cord-022561-rv5j1201	926	7	the	the	DT
cord-022561-rv5j1201	926	8	more	more	RBR
cord-022561-rv5j1201	926	9	economically	economically	RB
cord-022561-rv5j1201	926	10	or	or	CC
cord-022561-rv5j1201	926	11	regionally	regionally	RB
cord-022561-rv5j1201	926	12	important	important	JJ
cord-022561-rv5j1201	926	13	species	specie	NNS
cord-022561-rv5j1201	926	14	are	be	VBP
cord-022561-rv5j1201	926	15	mentioned	mention	VBN
cord-022561-rv5j1201	926	16	here	here	RB
cord-022561-rv5j1201	926	17	.	.	.
cord-022561-rv5j1201	927	1	Diseases	disease	NNS
cord-022561-rv5j1201	927	2	with	with	IN
cord-022561-rv5j1201	927	3	the	the	DT
cord-022561-rv5j1201	927	4	greatest	great	JJS
cord-022561-rv5j1201	927	5	economic	economic	JJ
cord-022561-rv5j1201	927	6	impact	impact	NN
cord-022561-rv5j1201	927	7	in	in	IN
cord-022561-rv5j1201	927	8	ruminants	ruminant	NNS
cord-022561-rv5j1201	927	9	are	be	VBP
cord-022561-rv5j1201	927	10	East	East	NNP
cord-022561-rv5j1201	927	11	Coast	Coast	NNP
cord-022561-rv5j1201	927	12	fever	fever	NN
cord-022561-rv5j1201	928	1	(	(	-LRB-
cord-022561-rv5j1201	928	2	Theileria	Theileria	NNP
cord-022561-rv5j1201	928	3	parva	parva	NNP
cord-022561-rv5j1201	928	4	infection	infection	NN
cord-022561-rv5j1201	928	5	)	)	-RRB-
cord-022561-rv5j1201	928	6	and	and	CC
cord-022561-rv5j1201	928	7	tropical	tropical	JJ
cord-022561-rv5j1201	928	8	theileriosis	theileriosis	NN
cord-022561-rv5j1201	929	1	(	(	-LRB-
cord-022561-rv5j1201	929	2	Theileria	Theileria	NNP
cord-022561-rv5j1201	929	3	annulata	annulata	NN
cord-022561-rv5j1201	929	4	infection	infection	NN
cord-022561-rv5j1201	929	5	)	)	-RRB-
cord-022561-rv5j1201	929	6	.	.	.
cord-022561-rv5j1201	930	1	•	•	NNP
cord-022561-rv5j1201	930	2	Horses	Horses	NNP
cord-022561-rv5j1201	930	3	-	-	HYPH
cord-022561-rv5j1201	930	4	Theileria	Theileria	NNP
cord-022561-rv5j1201	930	5	equi	equi	NN
cord-022561-rv5j1201	930	6	(	(	-LRB-
cord-022561-rv5j1201	930	7	formerly	formerly	RB
cord-022561-rv5j1201	930	8	Babesia	babesia	JJ
cord-022561-rv5j1201	930	9	equi	equi	NN
cord-022561-rv5j1201	930	10	)	)	-RRB-
cord-022561-rv5j1201	931	1	•	•	NNP
cord-022561-rv5j1201	932	1	Cattle	Cattle	NNS
cord-022561-rv5j1201	932	2	-	-	HYPH
cord-022561-rv5j1201	932	3	Theileria	Theileria	NNP
cord-022561-rv5j1201	932	4	annulata	annulata	NN
cord-022561-rv5j1201	932	5	,	,	,
cord-022561-rv5j1201	932	6	Theileria	Theileria	NNP
cord-022561-rv5j1201	932	7	buffeli	buffeli	NNP
cord-022561-rv5j1201	932	8	,	,	,
cord-022561-rv5j1201	933	1	T.	T.	NNP
cord-022561-rv5j1201	933	2	parva	parva	NNP
cord-022561-rv5j1201	934	1	•	•	NNP
cord-022561-rv5j1201	935	1	Sheep	Sheep	NNS
cord-022561-rv5j1201	935	2	and	and	CC
cord-022561-rv5j1201	935	3	goats	goat	NNS
cord-022561-rv5j1201	935	4	-	-	:
cord-022561-rv5j1201	935	5	Theileria	Theileria	NNP
cord-022561-rv5j1201	935	6	lestoquardi	lestoquardi	NNS
cord-022561-rv5j1201	935	7	(	(	-LRB-
cord-022561-rv5j1201	935	8	formerly	formerly	RB
cord-022561-rv5j1201	935	9	Theileria	Theileria	NNP
cord-022561-rv5j1201	935	10	hirci	hirci	NNP
cord-022561-rv5j1201	935	11	)	)	-RRB-
cord-022561-rv5j1201	936	1	Like	like	IN
cord-022561-rv5j1201	936	2	babesiosis	babesiosi	NNS
cord-022561-rv5j1201	936	3	,	,	,
cord-022561-rv5j1201	936	4	theileriosis	theileriosis	NNP
cord-022561-rv5j1201	936	5	is	be	VBZ
cord-022561-rv5j1201	936	6	generally	generally	RB
cord-022561-rv5j1201	936	7	restricted	restrict	VBN
cord-022561-rv5j1201	936	8	to	to	IN
cord-022561-rv5j1201	936	9	tropical	tropical	JJ
cord-022561-rv5j1201	936	10	and	and	CC
cord-022561-rv5j1201	936	11	subtropical	subtropical	JJ
cord-022561-rv5j1201	936	12	regions	region	NNS
cord-022561-rv5j1201	936	13	,	,	,
cord-022561-rv5j1201	936	14	including	include	VBG
cord-022561-rv5j1201	936	15	parts	part	NNS
cord-022561-rv5j1201	936	16	of	of	IN
cord-022561-rv5j1201	936	17	Africa	Africa	NNP
cord-022561-rv5j1201	936	18	,	,	,
cord-022561-rv5j1201	936	19	Asia	Asia	NNP
cord-022561-rv5j1201	936	20	,	,	,
cord-022561-rv5j1201	936	21	the	the	DT
cord-022561-rv5j1201	936	22	Middle	Middle	NNP
cord-022561-rv5j1201	936	23	East	East	NNP
cord-022561-rv5j1201	936	24	,	,	,
cord-022561-rv5j1201	936	25	and	and	CC
cord-022561-rv5j1201	936	26	Europe	Europe	NNP
cord-022561-rv5j1201	936	27	.	.	.
cord-022561-rv5j1201	937	1	Except	except	IN
cord-022561-rv5j1201	937	2	for	for	IN
cord-022561-rv5j1201	937	3	T.	t.	NN
cord-022561-rv5j1201	937	4	buffeli	buffeli	NNS
cord-022561-rv5j1201	937	5	,	,	,
cord-022561-rv5j1201	937	6	all	all	DT
cord-022561-rv5j1201	937	7	previously	previously	RB
cord-022561-rv5j1201	937	8	listed	list	VBN
cord-022561-rv5j1201	937	9	species	specie	NNS
cord-022561-rv5j1201	937	10	are	be	VBP
cord-022561-rv5j1201	937	11	exotic	exotic	JJ
cord-022561-rv5j1201	937	12	to	to	IN
cord-022561-rv5j1201	937	13	the	the	DT
cord-022561-rv5j1201	937	14	United	United	NNP
cord-022561-rv5j1201	937	15	States	States	NNP
cord-022561-rv5j1201	937	16	.	.	.
cord-022561-rv5j1201	938	1	Infection	infection	NN
cord-022561-rv5j1201	938	2	is	be	VBZ
cord-022561-rv5j1201	938	3	characterized	characterize	VBN
cord-022561-rv5j1201	938	4	by	by	IN
cord-022561-rv5j1201	938	5	schizonts	schizont	NNS
cord-022561-rv5j1201	938	6	within	within	IN
cord-022561-rv5j1201	938	7	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	938	8	or	or	CC
cord-022561-rv5j1201	938	9	monocytes	monocyte	NNS
cord-022561-rv5j1201	938	10	,	,	,
cord-022561-rv5j1201	938	11	and	and	CC
cord-022561-rv5j1201	938	12	pleomorphic	pleomorphic	JJ
cord-022561-rv5j1201	938	13	intraerythrocytic	intraerythrocytic	JJ
cord-022561-rv5j1201	938	14	piroplasms	piroplasm	NNS
cord-022561-rv5j1201	938	15	(	(	-LRB-
cord-022561-rv5j1201	938	16	merozoites	merozoite	NNS
cord-022561-rv5j1201	938	17	and	and	CC
cord-022561-rv5j1201	938	18	trophozoites	trophozoite	NNS
cord-022561-rv5j1201	938	19	)	)	-RRB-
cord-022561-rv5j1201	938	20	.	.	.
cord-022561-rv5j1201	939	1	Within	within	IN
cord-022561-rv5j1201	939	2	host	host	NN
cord-022561-rv5j1201	939	3	leukocytes	leukocyte	VBZ
cord-022561-rv5j1201	939	4	the	the	DT
cord-022561-rv5j1201	939	5	parasite	parasite	NN
cord-022561-rv5j1201	939	6	induces	induce	VBZ
cord-022561-rv5j1201	939	7	leukocyte	leukocyte	NNP
cord-022561-rv5j1201	939	8	cellular	cellular	JJ
cord-022561-rv5j1201	939	9	division	division	NN
cord-022561-rv5j1201	939	10	,	,	,
cord-022561-rv5j1201	939	11	which	which	WDT
cord-022561-rv5j1201	939	12	expands	expand	VBZ
cord-022561-rv5j1201	939	13	the	the	DT
cord-022561-rv5j1201	939	14	parasitized	parasitized	JJ
cord-022561-rv5j1201	939	15	cell	cell	NN
cord-022561-rv5j1201	939	16	population	population	NN
cord-022561-rv5j1201	939	17	.	.	.
cord-022561-rv5j1201	940	1	Infected	infected	JJ
cord-022561-rv5j1201	940	2	cells	cell	NNS
cord-022561-rv5j1201	940	3	disseminate	disseminate	VBP
cord-022561-rv5j1201	940	4	throughout	throughout	IN
cord-022561-rv5j1201	940	5	the	the	DT
cord-022561-rv5j1201	940	6	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	940	7	system	system	NN
cord-022561-rv5j1201	940	8	via	via	IN
cord-022561-rv5j1201	940	9	the	the	DT
cord-022561-rv5j1201	940	10	lymphatic	lymphatic	NN
cord-022561-rv5j1201	940	11	and	and	CC
cord-022561-rv5j1201	940	12	blood	blood	NN
cord-022561-rv5j1201	940	13	vessels	vessel	NNS
cord-022561-rv5j1201	940	14	.	.	.
cord-022561-rv5j1201	941	1	The	the	DT
cord-022561-rv5j1201	941	2	infected	infected	JJ
cord-022561-rv5j1201	941	3	leukocyte	leukocyte	NN
cord-022561-rv5j1201	941	4	may	may	MD
cord-022561-rv5j1201	941	5	block	block	VB
cord-022561-rv5j1201	941	6	capillaries	capillary	NNS
cord-022561-rv5j1201	941	7	,	,	,
cord-022561-rv5j1201	941	8	causing	cause	VBG
cord-022561-rv5j1201	941	9	tissue	tissue	NN
cord-022561-rv5j1201	941	10	ischemia	ischemia	NN
cord-022561-rv5j1201	941	11	.	.	.
cord-022561-rv5j1201	942	1	Later	later	RB
cord-022561-rv5j1201	942	2	in	in	IN
cord-022561-rv5j1201	942	3	infection	infection	NN
cord-022561-rv5j1201	942	4	some	some	DT
cord-022561-rv5j1201	942	5	schizonts	schizont	NNS
cord-022561-rv5j1201	942	6	cause	cause	VBP
cord-022561-rv5j1201	942	7	leukocyte	leukocyte	NN
cord-022561-rv5j1201	942	8	lysis	lysis	NN
cord-022561-rv5j1201	942	9	and	and	CC
cord-022561-rv5j1201	942	10	release	release	NN
cord-022561-rv5j1201	942	11	of	of	IN
cord-022561-rv5j1201	942	12	merozoites	merozoite	NNS
cord-022561-rv5j1201	942	13	.	.	.
cord-022561-rv5j1201	943	1	Merozoites	merozoite	NNS
cord-022561-rv5j1201	943	2	then	then	RB
cord-022561-rv5j1201	943	3	invade	invade	VB
cord-022561-rv5j1201	943	4	and	and	CC
cord-022561-rv5j1201	943	5	parasitize	parasitize	VB
cord-022561-rv5j1201	943	6	erythrocytes	erythrocyte	NNS
cord-022561-rv5j1201	943	7	,	,	,
cord-022561-rv5j1201	943	8	causing	cause	VBG
cord-022561-rv5j1201	943	9	hemolytic	hemolytic	JJ
cord-022561-rv5j1201	943	10	anemia	anemia	NN
cord-022561-rv5j1201	943	11	.	.	.
cord-022561-rv5j1201	944	1	Possible	possible	JJ
cord-022561-rv5j1201	944	2	mechanisms	mechanism	NNS
cord-022561-rv5j1201	944	3	of	of	IN
cord-022561-rv5j1201	944	4	anemia	anemia	NN
cord-022561-rv5j1201	944	5	in	in	IN
cord-022561-rv5j1201	944	6	theileriosis	theileriosis	NNP
cord-022561-rv5j1201	944	7	include	include	VBP
cord-022561-rv5j1201	944	8	invasion	invasion	NN
cord-022561-rv5j1201	944	9	of	of	IN
cord-022561-rv5j1201	944	10	erythroid	erythroid	JJ
cord-022561-rv5j1201	944	11	precursors	precursor	NNS
cord-022561-rv5j1201	944	12	by	by	IN
cord-022561-rv5j1201	944	13	merozoite	merozoite	NNP
cord-022561-rv5j1201	944	14	stages	stage	NNS
cord-022561-rv5j1201	944	15	and	and	CC
cord-022561-rv5j1201	944	16	associated	associated	JJ
cord-022561-rv5j1201	944	17	erythroid	erythroid	NN
cord-022561-rv5j1201	944	18	hypoplasia	hypoplasia	NN
cord-022561-rv5j1201	944	19	(	(	-LRB-
cord-022561-rv5j1201	944	20	as	as	IN
cord-022561-rv5j1201	944	21	occurs	occur	VBZ
cord-022561-rv5j1201	944	22	with	with	IN
cord-022561-rv5j1201	944	23	T.	T.	NNP
cord-022561-rv5j1201	944	24	parva	parva	NNP
cord-022561-rv5j1201	944	25	infection	infection	NN
cord-022561-rv5j1201	944	26	)	)	-RRB-
cord-022561-rv5j1201	944	27	,	,	,
cord-022561-rv5j1201	944	28	immune	immune	NN
cord-022561-rv5j1201	944	29	-	-	HYPH
cord-022561-rv5j1201	944	30	mediated	mediate	VBN
cord-022561-rv5j1201	944	31	hemolysis	hemolysis	NN
cord-022561-rv5j1201	944	32	,	,	,
cord-022561-rv5j1201	944	33	mechanical	mechanical	JJ
cord-022561-rv5j1201	944	34	fragmentation	fragmentation	NN
cord-022561-rv5j1201	944	35	because	because	IN
cord-022561-rv5j1201	944	36	of	of	IN
cord-022561-rv5j1201	944	37	vasculitis	vasculitis	NN
cord-022561-rv5j1201	944	38	or	or	CC
cord-022561-rv5j1201	944	39	microthrombi	microthrombi	NN
cord-022561-rv5j1201	944	40	,	,	,
cord-022561-rv5j1201	944	41	enzymatic	enzymatic	JJ
cord-022561-rv5j1201	944	42	destruction	destruction	NN
cord-022561-rv5j1201	944	43	by	by	IN
cord-022561-rv5j1201	944	44	proteases	protease	NNS
cord-022561-rv5j1201	944	45	,	,	,
cord-022561-rv5j1201	944	46	and	and	CC
cord-022561-rv5j1201	944	47	oxidative	oxidative	JJ
cord-022561-rv5j1201	944	48	damage	damage	NN
cord-022561-rv5j1201	944	49	.	.	.
cord-022561-rv5j1201	945	1	Gross	gross	JJ
cord-022561-rv5j1201	945	2	and	and	CC
cord-022561-rv5j1201	945	3	microscopic	microscopic	JJ
cord-022561-rv5j1201	945	4	lesions	lesion	NNS
cord-022561-rv5j1201	945	5	are	be	VBP
cord-022561-rv5j1201	945	6	similar	similar	JJ
cord-022561-rv5j1201	945	7	to	to	IN
cord-022561-rv5j1201	945	8	those	those	DT
cord-022561-rv5j1201	945	9	of	of	IN
cord-022561-rv5j1201	945	10	babesiosis	babesiosis	NN
cord-022561-rv5j1201	945	11	,	,	,
cord-022561-rv5j1201	945	12	except	except	IN
cord-022561-rv5j1201	945	13	that	that	DT
cord-022561-rv5j1201	945	14	cattle	cattle	NNS
cord-022561-rv5j1201	945	15	with	with	IN
cord-022561-rv5j1201	945	16	East	East	NNP
cord-022561-rv5j1201	945	17	Coast	Coast	NNP
cord-022561-rv5j1201	945	18	fever	fever	NN
cord-022561-rv5j1201	945	19	tend	tend	VBP
cord-022561-rv5j1201	945	20	not	not	RB
cord-022561-rv5j1201	945	21	to	to	TO
cord-022561-rv5j1201	945	22	develop	develop	VB
cord-022561-rv5j1201	945	23	organized	organize	VBN
cord-022561-rv5j1201	945	24	by	by	IN
cord-022561-rv5j1201	945	25	taxonomy	taxonomy	NN
cord-022561-rv5j1201	945	26	(	(	-LRB-
cord-022561-rv5j1201	945	27	protozoal	protozoal	NNP
cord-022561-rv5j1201	945	28	,	,	,
cord-022561-rv5j1201	945	29	bacterial	bacterial	JJ
cord-022561-rv5j1201	945	30	and	and	CC
cord-022561-rv5j1201	945	31	rickettsial	rickettsial	JJ
cord-022561-rv5j1201	945	32	,	,	,
cord-022561-rv5j1201	945	33	and	and	CC
cord-022561-rv5j1201	945	34	viral	viral	JJ
cord-022561-rv5j1201	945	35	)	)	-RRB-
cord-022561-rv5j1201	945	36	.	.	.
cord-022561-rv5j1201	946	1	Babesiosis	babesiosis	NN
cord-022561-rv5j1201	946	2	(	(	-LRB-
cord-022561-rv5j1201	946	3	Piroplasmosis	Piroplasmosis	NNP
cord-022561-rv5j1201	946	4	)	)	-RRB-
cord-022561-rv5j1201	946	5	.	.	.
cord-022561-rv5j1201	947	1	Babesia	Babesia	NNP
cord-022561-rv5j1201	947	2	spp	spp	NNS
cord-022561-rv5j1201	947	3	.	.	.
cord-022561-rv5j1201	948	1	and	and	CC
cord-022561-rv5j1201	948	2	Theileria	Theileria	NNP
cord-022561-rv5j1201	948	3	spp	spp	NNP
cord-022561-rv5j1201	948	4	.	.	.
cord-022561-rv5j1201	949	1	,	,	,
cord-022561-rv5j1201	949	2	presented	present	VBN
cord-022561-rv5j1201	949	3	in	in	IN
cord-022561-rv5j1201	949	4	the	the	DT
cord-022561-rv5j1201	949	5	next	next	JJ
cord-022561-rv5j1201	949	6	section	section	NN
cord-022561-rv5j1201	949	7	,	,	,
cord-022561-rv5j1201	949	8	are	be	VBP
cord-022561-rv5j1201	949	9	members	member	NNS
cord-022561-rv5j1201	949	10	of	of	IN
cord-022561-rv5j1201	949	11	the	the	DT
cord-022561-rv5j1201	949	12	order	order	NN
cord-022561-rv5j1201	949	13	Piroplasmida	Piroplasmida	NNP
cord-022561-rv5j1201	949	14	,	,	,
cord-022561-rv5j1201	949	15	and	and	CC
cord-022561-rv5j1201	949	16	are	be	VBP
cord-022561-rv5j1201	949	17	generally	generally	RB
cord-022561-rv5j1201	949	18	referenced	reference	VBN
cord-022561-rv5j1201	949	19	as	as	IN
cord-022561-rv5j1201	949	20	piroplasms	piroplasm	NNS
cord-022561-rv5j1201	949	21	.	.	.
cord-022561-rv5j1201	950	1	These	these	DT
cord-022561-rv5j1201	950	2	organisms	organism	NNS
cord-022561-rv5j1201	950	3	are	be	VBP
cord-022561-rv5j1201	950	4	morphologically	morphologically	RB
cord-022561-rv5j1201	950	5	similar	similar	JJ
cord-022561-rv5j1201	950	6	but	but	CC
cord-022561-rv5j1201	950	7	have	have	VBP
cord-022561-rv5j1201	950	8	different	different	JJ
cord-022561-rv5j1201	950	9	life	life	NN
cord-022561-rv5j1201	950	10	cycles	cycle	NNS
cord-022561-rv5j1201	950	11	;	;	:
cord-022561-rv5j1201	950	12	Babesia	Babesia	NNP
cord-022561-rv5j1201	950	13	spp	spp	NNS
cord-022561-rv5j1201	950	14	.	.	.
cord-022561-rv5j1201	951	1	are	be	VBP
cord-022561-rv5j1201	951	2	primarily	primarily	RB
cord-022561-rv5j1201	951	3	erythrocytic	erythrocytic	VBN
cord-022561-rv5j1201	951	4	parasites	parasite	NNS
cord-022561-rv5j1201	951	5	,	,	,
cord-022561-rv5j1201	951	6	whereas	whereas	IN
cord-022561-rv5j1201	951	7	Theileria	Theileria	NNP
cord-022561-rv5j1201	951	8	spp	spp	NNP
cord-022561-rv5j1201	951	9	.	.	.
cord-022561-rv5j1201	952	1	sequentially	sequentially	RB
cord-022561-rv5j1201	952	2	parasitize	parasitize	VB
cord-022561-rv5j1201	952	3	leukocytes	leukocyte	NNS
cord-022561-rv5j1201	952	4	and	and	CC
cord-022561-rv5j1201	952	5	then	then	RB
cord-022561-rv5j1201	952	6	erythrocytes	erythrocyte	VBZ
cord-022561-rv5j1201	952	7	.	.	.
cord-022561-rv5j1201	953	1	Both	both	DT
cord-022561-rv5j1201	953	2	are	be	VBP
cord-022561-rv5j1201	953	3	protozoan	protozoan	NN
cord-022561-rv5j1201	953	4	parasites	parasite	NNS
cord-022561-rv5j1201	953	5	spread	spread	VBN
cord-022561-rv5j1201	953	6	by	by	IN
cord-022561-rv5j1201	953	7	ticks	tick	NNS
cord-022561-rv5j1201	953	8	,	,	,
cord-022561-rv5j1201	953	9	but	but	CC
cord-022561-rv5j1201	953	10	other	other	JJ
cord-022561-rv5j1201	953	11	modes	mode	NNS
cord-022561-rv5j1201	953	12	of	of	IN
cord-022561-rv5j1201	953	13	transmission	transmission	NN
cord-022561-rv5j1201	953	14	are	be	VBP
cord-022561-rv5j1201	953	15	possible	possible	JJ
cord-022561-rv5j1201	953	16	(	(	-LRB-
cord-022561-rv5j1201	953	17	e.g.	e.g.	RB
cord-022561-rv5j1201	953	18	,	,	,
cord-022561-rv5j1201	953	19	biting	bite	VBG
cord-022561-rv5j1201	953	20	flies	fly	NNS
cord-022561-rv5j1201	953	21	,	,	,
cord-022561-rv5j1201	953	22	transplacental	transplacental	NNP
cord-022561-rv5j1201	953	23	,	,	,
cord-022561-rv5j1201	953	24	and	and	CC
cord-022561-rv5j1201	953	25	blood	blood	NN
cord-022561-rv5j1201	953	26	transfusions	transfusion	NNS
cord-022561-rv5j1201	953	27	)	)	-RRB-
cord-022561-rv5j1201	953	28	.	.	.
cord-022561-rv5j1201	954	1	Evidence	evidence	NN
cord-022561-rv5j1201	954	2	is	be	VBZ
cord-022561-rv5j1201	954	3	accumulating	accumulate	VBG
cord-022561-rv5j1201	954	4	that	that	DT
cord-022561-rv5j1201	954	5	dog	dog	NN
cord-022561-rv5j1201	954	6	fighting	fighting	NN
cord-022561-rv5j1201	954	7	also	also	RB
cord-022561-rv5j1201	954	8	transmits	transmit	VBZ
cord-022561-rv5j1201	954	9	Babesia	Babesia	NNP
cord-022561-rv5j1201	954	10	gibsoni	gibsoni	NNP
cord-022561-rv5j1201	954	11	infection	infection	NN
cord-022561-rv5j1201	954	12	.	.	.
cord-022561-rv5j1201	955	1	Babesia	babesia	JJ
cord-022561-rv5j1201	955	2	organisms	organism	NNS
cord-022561-rv5j1201	955	3	are	be	VBP
cord-022561-rv5j1201	955	4	typically	typically	RB
cord-022561-rv5j1201	955	5	classified	classify	VBN
cord-022561-rv5j1201	955	6	as	as	IN
cord-022561-rv5j1201	955	7	large	large	JJ
cord-022561-rv5j1201	955	8	(	(	-LRB-
cord-022561-rv5j1201	955	9	2	2	CD
cord-022561-rv5j1201	955	10	to	to	TO
cord-022561-rv5j1201	955	11	4	4	CD
cord-022561-rv5j1201	955	12	µm	µm	CD
cord-022561-rv5j1201	955	13	)	)	-RRB-
cord-022561-rv5j1201	955	14	or	or	CC
cord-022561-rv5j1201	955	15	small	small	JJ
cord-022561-rv5j1201	955	16	(	(	-LRB-
cord-022561-rv5j1201	955	17	<	<	XX
cord-022561-rv5j1201	955	18	2	2	CD
cord-022561-rv5j1201	955	19	µm	µm	CD
cord-022561-rv5j1201	955	20	)	)	-RRB-
cord-022561-rv5j1201	955	21	with	with	IN
cord-022561-rv5j1201	955	22	routine	routine	JJ
cord-022561-rv5j1201	955	23	light	light	JJ
cord-022561-rv5j1201	955	24	microscopy	microscopy	NNS
cord-022561-rv5j1201	955	25	(	(	-LRB-
cord-022561-rv5j1201	955	26	Fig	Fig	NNP
cord-022561-rv5j1201	955	27	.	.	.
cord-022561-rv5j1201	955	28	13	13	CD
cord-022561-rv5j1201	955	29	-	-	SYM
cord-022561-rv5j1201	955	30	24	24	CD
cord-022561-rv5j1201	955	31	)	)	-RRB-
cord-022561-rv5j1201	955	32	.	.	.
cord-022561-rv5j1201	956	1	Over	over	IN
cord-022561-rv5j1201	956	2	100	100	CD
cord-022561-rv5j1201	956	3	Babesia	Babesia	NNP
cord-022561-rv5j1201	956	4	species	specie	NNS
cord-022561-rv5j1201	956	5	have	have	VBP
cord-022561-rv5j1201	956	6	been	be	VBN
cord-022561-rv5j1201	956	7	identified	identify	VBN
cord-022561-rv5j1201	956	8	,	,	,
cord-022561-rv5j1201	956	9	some	some	DT
cord-022561-rv5j1201	956	10	of	of	IN
cord-022561-rv5j1201	956	11	which	which	WDT
cord-022561-rv5j1201	956	12	are	be	VBP
cord-022561-rv5j1201	956	13	listed	list	VBN
cord-022561-rv5j1201	956	14	here	here	RB
cord-022561-rv5j1201	956	15	,	,	,
cord-022561-rv5j1201	956	16	along	along	IN
cord-022561-rv5j1201	956	17	with	with	IN
cord-022561-rv5j1201	956	18	their	-PRON-	PRP$
cord-022561-rv5j1201	956	19	relative	relative	JJ
cord-022561-rv5j1201	956	20	microscopic	microscopic	JJ
cord-022561-rv5j1201	956	21	size	size	NN
cord-022561-rv5j1201	956	22	in	in	IN
cord-022561-rv5j1201	956	23	parentheses	parenthesis	NNS
cord-022561-rv5j1201	956	24	:	:	:
cord-022561-rv5j1201	956	25	Geographic	geographic	JJ
cord-022561-rv5j1201	956	26	distributions	distribution	NNS
cord-022561-rv5j1201	956	27	vary	vary	VBP
cord-022561-rv5j1201	956	28	with	with	IN
cord-022561-rv5j1201	956	29	the	the	DT
cord-022561-rv5j1201	956	30	species	specie	NNS
cord-022561-rv5j1201	956	31	,	,	,
cord-022561-rv5j1201	956	32	but	but	CC
cord-022561-rv5j1201	956	33	most	most	JJS
cord-022561-rv5j1201	956	34	have	have	VBP
cord-022561-rv5j1201	956	35	higher	high	JJR
cord-022561-rv5j1201	956	36	prevalences	prevalence	NNS
cord-022561-rv5j1201	956	37	in	in	IN
cord-022561-rv5j1201	956	38	tropical	tropical	JJ
cord-022561-rv5j1201	956	39	and	and	CC
cord-022561-rv5j1201	956	40	subtropical	subtropical	JJ
cord-022561-rv5j1201	956	41	regions	region	NNS
cord-022561-rv5j1201	956	42	.	.	.
cord-022561-rv5j1201	957	1	For	for	IN
cord-022561-rv5j1201	957	2	example	example	NN
cord-022561-rv5j1201	957	3	,	,	,
cord-022561-rv5j1201	957	4	equine	equine	NN
cord-022561-rv5j1201	957	5	and	and	CC
cord-022561-rv5j1201	957	6	bovine	bovine	JJ
cord-022561-rv5j1201	957	7	babesiosis	babesiosis	NN
cord-022561-rv5j1201	957	8	are	be	VBP
cord-022561-rv5j1201	957	9	endemic	endemic	JJ
cord-022561-rv5j1201	957	10	in	in	IN
cord-022561-rv5j1201	957	11	parts	part	NNS
cord-022561-rv5j1201	957	12	of	of	IN
cord-022561-rv5j1201	957	13	Africa	Africa	NNP
cord-022561-rv5j1201	957	14	,	,	,
cord-022561-rv5j1201	957	15	the	the	DT
cord-022561-rv5j1201	957	16	Middle	Middle	NNP
cord-022561-rv5j1201	957	17	East	East	NNP
cord-022561-rv5j1201	957	18	,	,	,
cord-022561-rv5j1201	957	19	Asia	Asia	NNP
cord-022561-rv5j1201	957	20	,	,	,
cord-022561-rv5j1201	957	21	Central	Central	NNP
cord-022561-rv5j1201	957	22	and	and	CC
cord-022561-rv5j1201	957	23	South	South	NNP
cord-022561-rv5j1201	957	24	America	America	NNP
cord-022561-rv5j1201	957	25	,	,	,
cord-022561-rv5j1201	957	26	the	the	DT
cord-022561-rv5j1201	957	27	Caribbean	Caribbean	NNP
cord-022561-rv5j1201	957	28	,	,	,
cord-022561-rv5j1201	957	29	and	and	CC
cord-022561-rv5j1201	957	30	Europe	Europe	NNP
cord-022561-rv5j1201	957	31	.	.	.
cord-022561-rv5j1201	958	1	Both	both	DT
cord-022561-rv5j1201	958	2	were	be	VBD
cord-022561-rv5j1201	958	3	eradicated	eradicate	VBN
cord-022561-rv5j1201	958	4	from	from	IN
cord-022561-rv5j1201	958	5	the	the	DT
cord-022561-rv5j1201	958	6	United	United	NNP
cord-022561-rv5j1201	958	7	States	States	NNP
cord-022561-rv5j1201	958	8	and	and	CC
cord-022561-rv5j1201	958	9	are	be	VBP
cord-022561-rv5j1201	958	10	now	now	RB
cord-022561-rv5j1201	958	11	considered	consider	VBN
cord-022561-rv5j1201	958	12	exotic	exotic	JJ
cord-022561-rv5j1201	958	13	diseases	disease	NNS
cord-022561-rv5j1201	958	14	in	in	IN
cord-022561-rv5j1201	958	15	that	that	DT
cord-022561-rv5j1201	958	16	country	country	NN
cord-022561-rv5j1201	958	17	.	.	.
cord-022561-rv5j1201	959	1	Of	of	IN
cord-022561-rv5j1201	959	2	the	the	DT
cord-022561-rv5j1201	959	3	previously	previously	RB
cord-022561-rv5j1201	959	4	mentioned	mention	VBN
cord-022561-rv5j1201	959	5	species	specie	NNS
cord-022561-rv5j1201	959	6	,	,	,
cord-022561-rv5j1201	959	7	only	only	RB
cord-022561-rv5j1201	959	8	agents	agent	NNS
cord-022561-rv5j1201	959	9	of	of	IN
cord-022561-rv5j1201	959	10	canine	canine	JJ
cord-022561-rv5j1201	959	11	babesiosis	babesiosi	NNS
cord-022561-rv5j1201	959	12	are	be	VBP
cord-022561-rv5j1201	959	13	thought	think	VBN
cord-022561-rv5j1201	959	14	to	to	TO
cord-022561-rv5j1201	959	15	be	be	VB
cord-022561-rv5j1201	959	16	endemic	endemic	JJ
cord-022561-rv5j1201	959	17	in	in	IN
cord-022561-rv5j1201	959	18	the	the	DT
cord-022561-rv5j1201	959	19	United	United	NNP
cord-022561-rv5j1201	959	20	States	States	NNP
cord-022561-rv5j1201	959	21	.	.	.
cord-022561-rv5j1201	960	1	Fever	fever	NN
cord-022561-rv5j1201	960	2	.	.	.
cord-022561-rv5j1201	961	1	Anaplasmosis	Anaplasmosis	NNP
cord-022561-rv5j1201	961	2	,	,	,
cord-022561-rv5j1201	961	3	ehrlichiosis	ehrlichiosis	NNP
cord-022561-rv5j1201	961	4	,	,	,
cord-022561-rv5j1201	961	5	heartwater	heartwater	NNP
cord-022561-rv5j1201	961	6	,	,	,
cord-022561-rv5j1201	961	7	and	and	CC
cord-022561-rv5j1201	961	8	tick	tick	VB
cord-022561-rv5j1201	961	9	-	-	HYPH
cord-022561-rv5j1201	961	10	borne	bear	VBN
cord-022561-rv5j1201	961	11	fever	fever	NN
cord-022561-rv5j1201	961	12	are	be	VBP
cord-022561-rv5j1201	961	13	tick	tick	NN
cord-022561-rv5j1201	961	14	-	-	HYPH
cord-022561-rv5j1201	961	15	borne	bear	VBN
cord-022561-rv5j1201	961	16	diseases	disease	NNS
cord-022561-rv5j1201	961	17	caused	cause	VBN
cord-022561-rv5j1201	961	18	by	by	IN
cord-022561-rv5j1201	961	19	small	small	JJ
cord-022561-rv5j1201	961	20	,	,	,
cord-022561-rv5j1201	961	21	pleomorphic	pleomorphic	JJ
cord-022561-rv5j1201	961	22	,	,	,
cord-022561-rv5j1201	961	23	Gramnegative	Gramnegative	NNP
cord-022561-rv5j1201	961	24	,	,	,
cord-022561-rv5j1201	961	25	obligate	obligate	VBP
cord-022561-rv5j1201	961	26	intracellular	intracellular	JJ
cord-022561-rv5j1201	961	27	bacteria	bacteria	NNS
cord-022561-rv5j1201	961	28	within	within	IN
cord-022561-rv5j1201	961	29	the	the	DT
cord-022561-rv5j1201	961	30	order	order	NN
cord-022561-rv5j1201	961	31	Rickettsiaceae	Rickettsiaceae	NNP
cord-022561-rv5j1201	961	32	,	,	,
cord-022561-rv5j1201	961	33	also	also	RB
cord-022561-rv5j1201	961	34	colloquially	colloquially	RB
cord-022561-rv5j1201	961	35	known	know	VBN
cord-022561-rv5j1201	961	36	as	as	IN
cord-022561-rv5j1201	961	37	rickettsias	rickettsias	NNP
cord-022561-rv5j1201	961	38	.	.	.
cord-022561-rv5j1201	962	1	As	as	IN
cord-022561-rv5j1201	962	2	a	a	DT
cord-022561-rv5j1201	962	3	group	group	NN
cord-022561-rv5j1201	962	4	,	,	,
cord-022561-rv5j1201	962	5	rickettsias	rickettsias	NNP
cord-022561-rv5j1201	962	6	primarily	primarily	RB
cord-022561-rv5j1201	962	7	infect	infect	VBP
cord-022561-rv5j1201	962	8	hematopoietic	hematopoietic	JJ
cord-022561-rv5j1201	962	9	cells	cell	NNS
cord-022561-rv5j1201	962	10	and	and	CC
cord-022561-rv5j1201	962	11	endothelial	endothelial	JJ
cord-022561-rv5j1201	962	12	cells	cell	NNS
cord-022561-rv5j1201	962	13	.	.	.
cord-022561-rv5j1201	963	1	Rickettsias	Rickettsias	NNP
cord-022561-rv5j1201	963	2	that	that	WDT
cord-022561-rv5j1201	963	3	predominantly	predominantly	RB
cord-022561-rv5j1201	963	4	infect	infect	VBP
cord-022561-rv5j1201	963	5	endothelial	endothelial	JJ
cord-022561-rv5j1201	963	6	cells	cell	NNS
cord-022561-rv5j1201	963	7	(	(	-LRB-
cord-022561-rv5j1201	964	1	e.g.	e.g.	RB
cord-022561-rv5j1201	964	2	,	,	,
cord-022561-rv5j1201	964	3	Rickettsia	Rickettsia	NNP
cord-022561-rv5j1201	964	4	rickettsii	rickettsii	NNP
cord-022561-rv5j1201	965	1	[	[	-LRB-
cord-022561-rv5j1201	965	2	Rocky	Rocky	NNP
cord-022561-rv5j1201	965	3	Mountain	Mountain	NNP
cord-022561-rv5j1201	965	4	spotted	spot	VBD
cord-022561-rv5j1201	965	5	fever	fever	NN
cord-022561-rv5j1201	965	6	]	]	-RRB-
cord-022561-rv5j1201	965	7	)	)	-RRB-
cord-022561-rv5j1201	965	8	,	,	,
cord-022561-rv5j1201	965	9	or	or	CC
cord-022561-rv5j1201	965	10	cause	cause	VB
cord-022561-rv5j1201	965	11	gastrointestinal	gastrointestinal	JJ
cord-022561-rv5j1201	965	12	disease	disease	NN
cord-022561-rv5j1201	965	13	(	(	-LRB-
cord-022561-rv5j1201	966	1	e.g.	e.g.	RB
cord-022561-rv5j1201	966	2	,	,	,
cord-022561-rv5j1201	966	3	Neorickettsia	Neorickettsia	NNP
cord-022561-rv5j1201	966	4	helminthoeca	helminthoeca	NNP
cord-022561-rv5j1201	966	5	[	[	-LRB-
cord-022561-rv5j1201	966	6	salmon	salmon	NN
cord-022561-rv5j1201	966	7	poisoning	poisoning	NN
cord-022561-rv5j1201	966	8	disease	disease	NN
cord-022561-rv5j1201	966	9	]	]	-RRB-
cord-022561-rv5j1201	966	10	and	and	CC
cord-022561-rv5j1201	966	11	Neorickettsia	Neorickettsia	NNP
cord-022561-rv5j1201	966	12	risticii	risticii	NN
cord-022561-rv5j1201	966	13	[	[	-LRB-
cord-022561-rv5j1201	966	14	Potomac	Potomac	NNP
cord-022561-rv5j1201	966	15	horse	horse	NN
cord-022561-rv5j1201	966	16	fever	fever	NN
cord-022561-rv5j1201	966	17	]	]	-RRB-
cord-022561-rv5j1201	966	18	)	)	-RRB-
cord-022561-rv5j1201	966	19	are	be	VBP
cord-022561-rv5j1201	966	20	discussed	discuss	VBN
cord-022561-rv5j1201	966	21	elsewhere	elsewhere	RB
cord-022561-rv5j1201	966	22	(	(	-LRB-
cord-022561-rv5j1201	966	23	see	see	VB
cord-022561-rv5j1201	966	24	Chapters	chapter	NNS
cord-022561-rv5j1201	966	25	4	4	CD
cord-022561-rv5j1201	966	26	and	and	CC
cord-022561-rv5j1201	966	27	7	7	CD
cord-022561-rv5j1201	966	28	)	)	-RRB-
cord-022561-rv5j1201	966	29	.	.	.
cord-022561-rv5j1201	967	1	Less	less	RBR
cord-022561-rv5j1201	967	2	commonly	commonly	RB
cord-022561-rv5j1201	967	3	,	,	,
cord-022561-rv5j1201	967	4	transmission	transmission	NN
cord-022561-rv5j1201	967	5	may	may	MD
cord-022561-rv5j1201	967	6	occur	occur	VB
cord-022561-rv5j1201	967	7	via	via	IN
cord-022561-rv5j1201	967	8	blood	blood	NN
cord-022561-rv5j1201	967	9	transfusions	transfusion	NNS
cord-022561-rv5j1201	967	10	or	or	CC
cord-022561-rv5j1201	967	11	blood	blood	NN
cord-022561-rv5j1201	967	12	-	-	HYPH
cord-022561-rv5j1201	967	13	contaminated	contaminate	VBN
cord-022561-rv5j1201	967	14	medical	medical	JJ
cord-022561-rv5j1201	967	15	supplies	supply	NNS
cord-022561-rv5j1201	967	16	.	.	.
cord-022561-rv5j1201	968	1	Rickettsias	Rickettsias	NNP
cord-022561-rv5j1201	968	2	that	that	WDT
cord-022561-rv5j1201	968	3	infect	infect	VBP
cord-022561-rv5j1201	968	4	erythrocytes	erythrocyte	NNS
cord-022561-rv5j1201	968	5	include	include	VBP
cord-022561-rv5j1201	968	6	the	the	DT
cord-022561-rv5j1201	968	7	following	follow	VBG
cord-022561-rv5j1201	968	8	species	specie	NNS
cord-022561-rv5j1201	968	9	(	(	-LRB-
cord-022561-rv5j1201	968	10	the	the	DT
cord-022561-rv5j1201	968	11	disease	disease	NN
cord-022561-rv5j1201	968	12	name	name	NN
cord-022561-rv5j1201	968	13	follows	follow	VBZ
cord-022561-rv5j1201	968	14	in	in	IN
cord-022561-rv5j1201	968	15	parentheses	parenthesis	NNS
cord-022561-rv5j1201	968	16	)	)	-RRB-
cord-022561-rv5j1201	968	17	:	:	:
cord-022561-rv5j1201	969	1	•	•	NNP
cord-022561-rv5j1201	969	2	Cattle	Cattle	NNP
cord-022561-rv5j1201	969	3	-	-	HYPH
cord-022561-rv5j1201	969	4	Anaplasma	Anaplasma	NNP
cord-022561-rv5j1201	969	5	marginale	marginale	NN
cord-022561-rv5j1201	969	6	,	,	,
cord-022561-rv5j1201	969	7	Anaplasma	Anaplasma	NNP
cord-022561-rv5j1201	969	8	centrale	centrale	NNP
cord-022561-rv5j1201	969	9	(	(	-LRB-
cord-022561-rv5j1201	969	10	bovine	bovine	JJ
cord-022561-rv5j1201	969	11	anaplasmosis	anaplasmosis	NNP
cord-022561-rv5j1201	969	12	)	)	-RRB-
cord-022561-rv5j1201	970	1	•	•	NNP
cord-022561-rv5j1201	971	1	Sheep	Sheep	NNS
cord-022561-rv5j1201	971	2	and	and	CC
cord-022561-rv5j1201	971	3	goats	goat	NNS
cord-022561-rv5j1201	971	4	-	-	:
cord-022561-rv5j1201	971	5	Anaplasma	Anaplasma	NNP
cord-022561-rv5j1201	971	6	ovis	ovis	NN
cord-022561-rv5j1201	971	7	(	(	-LRB-
cord-022561-rv5j1201	971	8	ovine	ovine	NNP
cord-022561-rv5j1201	971	9	and	and	CC
cord-022561-rv5j1201	971	10	caprine	caprine	NNP
cord-022561-rv5j1201	971	11	anaplasmosis	anaplasmosis	NNP
cord-022561-rv5j1201	971	12	,	,	,
cord-022561-rv5j1201	971	13	respectively	respectively	RB
cord-022561-rv5j1201	971	14	)	)	-RRB-
cord-022561-rv5j1201	972	1	Anaplasma	Anaplasma	NNP
cord-022561-rv5j1201	972	2	marginale	marginale	NN
cord-022561-rv5j1201	972	3	and	and	CC
cord-022561-rv5j1201	972	4	A.	a.	NN
cord-022561-rv5j1201	972	5	ovis	ovis	NN
cord-022561-rv5j1201	972	6	have	have	VBP
cord-022561-rv5j1201	972	7	worldwide	worldwide	JJ
cord-022561-rv5j1201	972	8	distributions	distribution	NNS
cord-022561-rv5j1201	972	9	,	,	,
cord-022561-rv5j1201	972	10	but	but	CC
cord-022561-rv5j1201	972	11	A.	A.	NNP
cord-022561-rv5j1201	972	12	centrale	centrale	NNP
cord-022561-rv5j1201	972	13	is	be	VBZ
cord-022561-rv5j1201	972	14	mostly	mostly	RB
cord-022561-rv5j1201	972	15	restricted	restricted	JJ
cord-022561-rv5j1201	972	16	to	to	IN
cord-022561-rv5j1201	972	17	South	South	NNP
cord-022561-rv5j1201	972	18	America	America	NNP
cord-022561-rv5j1201	972	19	,	,	,
cord-022561-rv5j1201	972	20	Africa	Africa	NNP
cord-022561-rv5j1201	972	21	,	,	,
cord-022561-rv5j1201	972	22	and	and	CC
cord-022561-rv5j1201	972	23	the	the	DT
cord-022561-rv5j1201	972	24	Middle	Middle	NNP
cord-022561-rv5j1201	972	25	East	East	NNP
cord-022561-rv5j1201	972	26	.	.	.
cord-022561-rv5j1201	973	1	hemolytic	hemolytic	JJ
cord-022561-rv5j1201	973	2	anemia	anemia	NN
cord-022561-rv5j1201	973	3	.	.	.
cord-022561-rv5j1201	974	1	In	in	IN
cord-022561-rv5j1201	974	2	acute	acute	JJ
cord-022561-rv5j1201	974	3	East	East	NNP
cord-022561-rv5j1201	974	4	Coast	Coast	NNP
cord-022561-rv5j1201	974	5	fever	fever	NN
cord-022561-rv5j1201	974	6	,	,	,
cord-022561-rv5j1201	974	7	lymph	lymph	NN
cord-022561-rv5j1201	974	8	nodes	node	NNS
cord-022561-rv5j1201	974	9	are	be	VBP
cord-022561-rv5j1201	974	10	enlarged	enlarge	VBN
cord-022561-rv5j1201	974	11	,	,	,
cord-022561-rv5j1201	974	12	edematous	edematous	JJ
cord-022561-rv5j1201	974	13	,	,	,
cord-022561-rv5j1201	974	14	and	and	CC
cord-022561-rv5j1201	974	15	hemorrhagic	hemorrhagic	JJ
cord-022561-rv5j1201	974	16	.	.	.
cord-022561-rv5j1201	975	1	But	but	CC
cord-022561-rv5j1201	975	2	with	with	IN
cord-022561-rv5j1201	975	3	chronic	chronic	JJ
cord-022561-rv5j1201	975	4	cases	case	NNS
cord-022561-rv5j1201	975	5	they	-PRON-	PRP
cord-022561-rv5j1201	975	6	may	may	MD
cord-022561-rv5j1201	975	7	be	be	VB
cord-022561-rv5j1201	975	8	shrunken	shrunken	JJ
cord-022561-rv5j1201	975	9	.	.	.
cord-022561-rv5j1201	976	1	There	there	EX
cord-022561-rv5j1201	976	2	is	be	VBZ
cord-022561-rv5j1201	976	3	often	often	RB
cord-022561-rv5j1201	976	4	splenomegaly	splenomegaly	JJ
cord-022561-rv5j1201	976	5	,	,	,
cord-022561-rv5j1201	976	6	hepatomegaly	hepatomegaly	NNP
cord-022561-rv5j1201	976	7	,	,	,
cord-022561-rv5j1201	976	8	and	and	CC
cord-022561-rv5j1201	976	9	hemorrhagic	hemorrhagic	JJ
cord-022561-rv5j1201	976	10	enteritis	enteritis	NN
cord-022561-rv5j1201	976	11	with	with	IN
cord-022561-rv5j1201	976	12	white	white	JJ
cord-022561-rv5j1201	976	13	foci	foci	NN
cord-022561-rv5j1201	976	14	of	of	IN
cord-022561-rv5j1201	976	15	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	976	16	infiltrates	infiltrate	VBZ
cord-022561-rv5j1201	976	17	(	(	-LRB-
cord-022561-rv5j1201	976	18	pseudoinfarcts	pseudoinfarcts	NNP
cord-022561-rv5j1201	976	19	)	)	-RRB-
cord-022561-rv5j1201	976	20	in	in	IN
cord-022561-rv5j1201	976	21	the	the	DT
cord-022561-rv5j1201	976	22	liver	liver	NN
cord-022561-rv5j1201	976	23	and	and	CC
cord-022561-rv5j1201	976	24	kidney	kidney	NN
cord-022561-rv5j1201	976	25	.	.	.
cord-022561-rv5j1201	977	1	Microscopically	microscopically	RB
cord-022561-rv5j1201	977	2	,	,	,
cord-022561-rv5j1201	977	3	infected	infected	JJ
cord-022561-rv5j1201	977	4	leukocytes	leukocyte	NNS
cord-022561-rv5j1201	977	5	may	may	MD
cord-022561-rv5j1201	977	6	block	block	VB
cord-022561-rv5j1201	977	7	capillaries	capillary	NNS
cord-022561-rv5j1201	977	8	.	.	.
cord-022561-rv5j1201	978	1	African	African	NNP
cord-022561-rv5j1201	978	2	Trypanosomiasis	Trypanosomiasis	NNP
cord-022561-rv5j1201	978	3	.	.	.
cord-022561-rv5j1201	979	1	Trypanosomes	trypanosome	NNS
cord-022561-rv5j1201	979	2	are	be	VBP
cord-022561-rv5j1201	979	3	flagellated	flagellate	VBN
cord-022561-rv5j1201	979	4	protozoa	protozoan	NNS
cord-022561-rv5j1201	979	5	that	that	WDT
cord-022561-rv5j1201	979	6	can	can	MD
cord-022561-rv5j1201	979	7	infect	infect	VB
cord-022561-rv5j1201	979	8	all	all	DT
cord-022561-rv5j1201	979	9	domesticated	domesticate	VBN
cord-022561-rv5j1201	979	10	animals	animal	NNS
cord-022561-rv5j1201	979	11	.	.	.
cord-022561-rv5j1201	980	1	The	the	DT
cord-022561-rv5j1201	980	2	most	most	RBS
cord-022561-rv5j1201	980	3	important	important	JJ
cord-022561-rv5j1201	980	4	species	specie	NNS
cord-022561-rv5j1201	980	5	that	that	WDT
cord-022561-rv5j1201	980	6	cause	cause	VBP
cord-022561-rv5j1201	980	7	disease	disease	NN
cord-022561-rv5j1201	980	8	are	be	VBP
cord-022561-rv5j1201	980	9	Trypanosoma	Trypanosoma	NNP
cord-022561-rv5j1201	980	10	congolense	congolense	NN
cord-022561-rv5j1201	980	11	,	,	,
cord-022561-rv5j1201	980	12	Trypanosoma	Trypanosoma	NNP
cord-022561-rv5j1201	980	13	vivax	vivax	NN
cord-022561-rv5j1201	980	14	,	,	,
cord-022561-rv5j1201	980	15	and	and	CC
cord-022561-rv5j1201	980	16	Trypanosoma	Trypanosoma	NNP
cord-022561-rv5j1201	980	17	brucei	brucei	NNP
cord-022561-rv5j1201	980	18	ssp	ssp	NNP
cord-022561-rv5j1201	980	19	.	.	.
cord-022561-rv5j1201	981	1	brucei	brucei	NNP
cord-022561-rv5j1201	981	2	.	.	.
cord-022561-rv5j1201	982	1	Disease	Disease	NNP
cord-022561-rv5j1201	982	2	is	be	VBZ
cord-022561-rv5j1201	982	3	most	most	RBS
cord-022561-rv5j1201	982	4	common	common	JJ
cord-022561-rv5j1201	982	5	in	in	IN
cord-022561-rv5j1201	982	6	parts	part	NNS
cord-022561-rv5j1201	982	7	of	of	IN
cord-022561-rv5j1201	982	8	Africa	Africa	NNP
cord-022561-rv5j1201	982	9	where	where	WRB
cord-022561-rv5j1201	982	10	the	the	DT
cord-022561-rv5j1201	982	11	biologic	biologic	JJ
cord-022561-rv5j1201	982	12	vector	vector	NN
cord-022561-rv5j1201	982	13	,	,	,
cord-022561-rv5j1201	982	14	the	the	DT
cord-022561-rv5j1201	982	15	tsetse	tsetse	NN
cord-022561-rv5j1201	982	16	fly	fly	VB
cord-022561-rv5j1201	982	17	,	,	,
cord-022561-rv5j1201	982	18	exists	exist	VBZ
cord-022561-rv5j1201	982	19	.	.	.
cord-022561-rv5j1201	983	1	However	however	RB
cord-022561-rv5j1201	983	2	,	,	,
cord-022561-rv5j1201	983	3	T.	T.	NNP
cord-022561-rv5j1201	983	4	vivax	vivax	NN
cord-022561-rv5j1201	983	5	has	have	VBZ
cord-022561-rv5j1201	983	6	spread	spread	VBN
cord-022561-rv5j1201	983	7	to	to	IN
cord-022561-rv5j1201	983	8	Central	Central	NNP
cord-022561-rv5j1201	983	9	and	and	CC
cord-022561-rv5j1201	983	10	South	South	NNP
cord-022561-rv5j1201	983	11	America	America	NNP
cord-022561-rv5j1201	983	12	and	and	CC
cord-022561-rv5j1201	983	13	the	the	DT
cord-022561-rv5j1201	983	14	Caribbean	Caribbean	NNP
cord-022561-rv5j1201	983	15	,	,	,
cord-022561-rv5j1201	983	16	where	where	WRB
cord-022561-rv5j1201	983	17	other	other	JJ
cord-022561-rv5j1201	983	18	biting	bite	VBG
cord-022561-rv5j1201	983	19	flies	fly	NNS
cord-022561-rv5j1201	983	20	transmit	transmit	VBP
cord-022561-rv5j1201	983	21	the	the	DT
cord-022561-rv5j1201	983	22	parasite	parasite	NN
cord-022561-rv5j1201	983	23	mechanically	mechanically	RB
cord-022561-rv5j1201	983	24	.	.	.
cord-022561-rv5j1201	984	1	In	in	IN
cord-022561-rv5j1201	984	2	Africa	Africa	NNP
cord-022561-rv5j1201	984	3	,	,	,
cord-022561-rv5j1201	984	4	cattle	cattle	NNS
cord-022561-rv5j1201	984	5	are	be	VBP
cord-022561-rv5j1201	984	6	mainly	mainly	RB
cord-022561-rv5j1201	984	7	affected	affect	VBN
cord-022561-rv5j1201	984	8	due	due	IN
cord-022561-rv5j1201	984	9	to	to	IN
cord-022561-rv5j1201	984	10	the	the	DT
cord-022561-rv5j1201	984	11	feeding	feeding	NN
cord-022561-rv5j1201	984	12	preferences	preference	NNS
cord-022561-rv5j1201	984	13	of	of	IN
cord-022561-rv5j1201	984	14	the	the	DT
cord-022561-rv5j1201	984	15	tsetse	tsetse	NN
cord-022561-rv5j1201	984	16	fly	fly	VB
cord-022561-rv5j1201	984	17	.	.	.
cord-022561-rv5j1201	985	1	African	african	JJ
cord-022561-rv5j1201	985	2	trypanosomiasis	trypanosomiasis	NN
cord-022561-rv5j1201	985	3	must	must	MD
cord-022561-rv5j1201	985	4	be	be	VB
cord-022561-rv5j1201	985	5	distinguished	distinguish	VBN
cord-022561-rv5j1201	985	6	from	from	IN
cord-022561-rv5j1201	985	7	nonpathogenic	nonpathogenic	NNP
cord-022561-rv5j1201	985	8	trypanosomiasis	trypanosomiasis	NN
cord-022561-rv5j1201	985	9	,	,	,
cord-022561-rv5j1201	985	10	such	such	JJ
cord-022561-rv5j1201	985	11	as	as	IN
cord-022561-rv5j1201	985	12	Trypanosoma	Trypanosoma	NNP
cord-022561-rv5j1201	985	13	theileri	theileri	VBP
cord-022561-rv5j1201	985	14	infection	infection	NN
cord-022561-rv5j1201	985	15	in	in	IN
cord-022561-rv5j1201	985	16	cattle	cattle	NNS
cord-022561-rv5j1201	985	17	.	.	.
cord-022561-rv5j1201	986	1	Animals	animal	NNS
cord-022561-rv5j1201	986	2	become	become	VBP
cord-022561-rv5j1201	986	3	infected	infected	JJ
cord-022561-rv5j1201	986	4	when	when	WRB
cord-022561-rv5j1201	986	5	feeding	feed	VBG
cord-022561-rv5j1201	986	6	tsetse	tsetse	NN
cord-022561-rv5j1201	986	7	flies	fly	NNS
cord-022561-rv5j1201	986	8	inoculate	inoculate	VBP
cord-022561-rv5j1201	986	9	metacyclic	metacyclic	JJ
cord-022561-rv5j1201	986	10	trypanosomes	trypanosome	NNS
cord-022561-rv5j1201	986	11	into	into	IN
cord-022561-rv5j1201	986	12	the	the	DT
cord-022561-rv5j1201	986	13	skin	skin	NN
cord-022561-rv5j1201	986	14	of	of	IN
cord-022561-rv5j1201	986	15	animals	animal	NNS
cord-022561-rv5j1201	986	16	.	.	.
cord-022561-rv5j1201	987	1	The	the	DT
cord-022561-rv5j1201	987	2	trypanosomes	trypanosome	NNS
cord-022561-rv5j1201	987	3	grow	grow	VBP
cord-022561-rv5j1201	987	4	for	for	IN
cord-022561-rv5j1201	987	5	a	a	DT
cord-022561-rv5j1201	987	6	few	few	JJ
cord-022561-rv5j1201	987	7	days	day	NNS
cord-022561-rv5j1201	987	8	,	,	,
cord-022561-rv5j1201	987	9	causing	cause	VBG
cord-022561-rv5j1201	987	10	a	a	DT
cord-022561-rv5j1201	987	11	localized	localized	JJ
cord-022561-rv5j1201	987	12	chancre	chancre	NN
cord-022561-rv5j1201	987	13	sore	sore	JJ
cord-022561-rv5j1201	987	14	,	,	,
cord-022561-rv5j1201	987	15	and	and	CC
cord-022561-rv5j1201	987	16	then	then	RB
cord-022561-rv5j1201	987	17	sequentially	sequentially	RB
cord-022561-rv5j1201	987	18	enter	enter	VBP
cord-022561-rv5j1201	987	19	the	the	DT
cord-022561-rv5j1201	987	20	lymph	lymph	NN
cord-022561-rv5j1201	987	21	nodes	node	NNS
cord-022561-rv5j1201	987	22	and	and	CC
cord-022561-rv5j1201	987	23	bloodstream	bloodstream	NN
cord-022561-rv5j1201	987	24	.	.	.
cord-022561-rv5j1201	988	1	Trypanosomal	trypanosomal	JJ
cord-022561-rv5j1201	988	2	organisms	organism	NNS
cord-022561-rv5j1201	988	3	do	do	VBP
cord-022561-rv5j1201	988	4	not	not	RB
cord-022561-rv5j1201	988	5	infect	infect	VB
cord-022561-rv5j1201	988	6	erythrocytes	erythrocyte	NNS
cord-022561-rv5j1201	988	7	but	but	CC
cord-022561-rv5j1201	988	8	rather	rather	RB
cord-022561-rv5j1201	988	9	exist	exist	VBP
cord-022561-rv5j1201	988	10	as	as	IN
cord-022561-rv5j1201	988	11	free	free	JJ
cord-022561-rv5j1201	988	12	trypomastigotes	trypomastigote	NNS
cord-022561-rv5j1201	988	13	(	(	-LRB-
cord-022561-rv5j1201	988	14	i.e.	i.e.	FW
cord-022561-rv5j1201	988	15	,	,	,
cord-022561-rv5j1201	988	16	flagellated	flagellated	JJ
cord-022561-rv5j1201	988	17	protozoa	protozoan	NNS
cord-022561-rv5j1201	988	18	with	with	IN
cord-022561-rv5j1201	988	19	a	a	DT
cord-022561-rv5j1201	988	20	characteristic	characteristic	JJ
cord-022561-rv5j1201	988	21	undulating	undulating	JJ
cord-022561-rv5j1201	988	22	membrane	membrane	NN
cord-022561-rv5j1201	988	23	)	)	-RRB-
cord-022561-rv5j1201	988	24	in	in	IN
cord-022561-rv5j1201	988	25	the	the	DT
cord-022561-rv5j1201	988	26	blood	blood	NN
cord-022561-rv5j1201	988	27	(	(	-LRB-
cord-022561-rv5j1201	988	28	Fig	Fig	NNP
cord-022561-rv5j1201	988	29	.	.	.
cord-022561-rv5j1201	988	30	13	13	CD
cord-022561-rv5j1201	988	31	-25	-25	NN
cord-022561-rv5j1201	988	32	,	,	,
cord-022561-rv5j1201	988	33	A	A	NNP
cord-022561-rv5j1201	988	34	)	)	-RRB-
cord-022561-rv5j1201	988	35	or	or	CC
cord-022561-rv5j1201	988	36	as	as	IN
cord-022561-rv5j1201	988	37	amastigotes	amastigote	NNS
cord-022561-rv5j1201	988	38	in	in	IN
cord-022561-rv5j1201	988	39	tissue	tissue	NN
cord-022561-rv5j1201	988	40	.	.	.
cord-022561-rv5j1201	989	1	The	the	DT
cord-022561-rv5j1201	989	2	mechanism	mechanism	NN
cord-022561-rv5j1201	989	3	of	of	IN
cord-022561-rv5j1201	989	4	anemia	anemia	NN
cord-022561-rv5j1201	989	5	is	be	VBZ
cord-022561-rv5j1201	989	6	believed	believe	VBN
cord-022561-rv5j1201	989	7	to	to	TO
cord-022561-rv5j1201	989	8	be	be	VB
cord-022561-rv5j1201	989	9	immune	immune	JJ
cord-022561-rv5j1201	989	10	mediated	mediate	VBN
cord-022561-rv5j1201	989	11	.	.	.
cord-022561-rv5j1201	990	1	Cattle	Cattle	NNS
cord-022561-rv5j1201	990	2	with	with	IN
cord-022561-rv5j1201	990	3	acute	acute	JJ
cord-022561-rv5j1201	990	4	trypanosomiasis	trypanosomiasis	NN
cord-022561-rv5j1201	990	5	have	have	VBP
cord-022561-rv5j1201	990	6	significant	significant	JJ
cord-022561-rv5j1201	990	7	anemia	anemia	NN
cord-022561-rv5j1201	990	8	,	,	,
cord-022561-rv5j1201	990	9	which	which	WDT
cord-022561-rv5j1201	990	10	initially	initially	RB
cord-022561-rv5j1201	990	11	is	be	VBZ
cord-022561-rv5j1201	990	12	regenerative	regenerative	JJ
cord-022561-rv5j1201	990	13	,	,	,
cord-022561-rv5j1201	990	14	but	but	CC
cord-022561-rv5j1201	990	15	less	less	RBR
cord-022561-rv5j1201	990	16	so	so	RB
cord-022561-rv5j1201	990	17	with	with	IN
cord-022561-rv5j1201	990	18	time	time	NN
cord-022561-rv5j1201	990	19	.	.	.
cord-022561-rv5j1201	991	1	The	the	DT
cord-022561-rv5j1201	991	2	extent	extent	NN
cord-022561-rv5j1201	991	3	of	of	IN
cord-022561-rv5j1201	991	4	parasitemia	parasitemia	NNP
cord-022561-rv5j1201	991	5	is	be	VBZ
cord-022561-rv5j1201	991	6	readily	readily	RB
cord-022561-rv5j1201	991	7	apparent	apparent	JJ
cord-022561-rv5j1201	991	8	with	with	IN
cord-022561-rv5j1201	991	9	T.	t.	NN
cord-022561-rv5j1201	991	10	vivax	vivax	NN
cord-022561-rv5j1201	991	11	and	and	CC
cord-022561-rv5j1201	991	12	T.	t.	NN
cord-022561-rv5j1201	991	13	theileri	theileri	NN
cord-022561-rv5j1201	991	14	infections	infection	NNS
cord-022561-rv5j1201	991	15	because	because	IN
cord-022561-rv5j1201	991	16	the	the	DT
cord-022561-rv5j1201	991	17	organisms	organism	NNS
cord-022561-rv5j1201	991	18	are	be	VBP
cord-022561-rv5j1201	991	19	present	present	JJ
cord-022561-rv5j1201	991	20	in	in	IN
cord-022561-rv5j1201	991	21	large	large	JJ
cord-022561-rv5j1201	991	22	numbers	number	NNS
cord-022561-rv5j1201	991	23	in	in	IN
cord-022561-rv5j1201	991	24	the	the	DT
cord-022561-rv5j1201	991	25	blood	blood	NN
cord-022561-rv5j1201	991	26	.	.	.
cord-022561-rv5j1201	992	1	This	this	DT
cord-022561-rv5j1201	992	2	is	be	VBZ
cord-022561-rv5j1201	992	3	in	in	IN
cord-022561-rv5j1201	992	4	contrast	contrast	NN
cord-022561-rv5j1201	992	5	to	to	IN
cord-022561-rv5j1201	992	6	T.	t.	NN
cord-022561-rv5j1201	992	7	congolense	congolense	NN
cord-022561-rv5j1201	992	8	,	,	,
cord-022561-rv5j1201	992	9	which	which	WDT
cord-022561-rv5j1201	992	10	localizes	localize	VBZ
cord-022561-rv5j1201	992	11	within	within	IN
cord-022561-rv5j1201	992	12	the	the	DT
cord-022561-rv5j1201	992	13	vasculature	vasculature	NN
cord-022561-rv5j1201	992	14	of	of	IN
cord-022561-rv5j1201	992	15	the	the	DT
cord-022561-rv5j1201	992	16	brain	brain	NN
cord-022561-rv5j1201	992	17	and	and	CC
cord-022561-rv5j1201	992	18	skeletal	skeletal	JJ
cord-022561-rv5j1201	992	19	muscle	muscle	NN
cord-022561-rv5j1201	992	20	.	.	.
cord-022561-rv5j1201	993	1	Chronically	chronically	RB
cord-022561-rv5j1201	993	2	infected	infected	JJ
cord-022561-rv5j1201	993	3	animals	animal	NNS
cord-022561-rv5j1201	993	4	often	often	RB
cord-022561-rv5j1201	993	5	die	die	VBP
cord-022561-rv5j1201	993	6	secondary	secondary	JJ
cord-022561-rv5j1201	993	7	to	to	IN
cord-022561-rv5j1201	993	8	poor	poor	JJ
cord-022561-rv5j1201	993	9	body	body	NN
cord-022561-rv5j1201	993	10	condition	condition	NN
cord-022561-rv5j1201	993	11	,	,	,
cord-022561-rv5j1201	993	12	immunosuppression	immunosuppression	NN
cord-022561-rv5j1201	993	13	,	,	,
cord-022561-rv5j1201	993	14	and	and	CC
cord-022561-rv5j1201	993	15	concurrent	concurrent	JJ
cord-022561-rv5j1201	993	16	infections	infection	NNS
cord-022561-rv5j1201	993	17	.	.	.
cord-022561-rv5j1201	994	1	Gross	gross	JJ
cord-022561-rv5j1201	994	2	examination	examination	NN
cord-022561-rv5j1201	994	3	of	of	IN
cord-022561-rv5j1201	994	4	animals	animal	NNS
cord-022561-rv5j1201	994	5	with	with	IN
cord-022561-rv5j1201	994	6	acute	acute	JJ
cord-022561-rv5j1201	994	7	disease	disease	NN
cord-022561-rv5j1201	994	8	often	often	RB
cord-022561-rv5j1201	994	9	reveals	reveal	VBZ
cord-022561-rv5j1201	994	10	generalized	generalize	VBN
cord-022561-rv5j1201	994	11	lymphadenomegaly	lymphadenomegaly	NNS
cord-022561-rv5j1201	994	12	,	,	,
cord-022561-rv5j1201	994	13	splenomegaly	splenomegaly	NN
cord-022561-rv5j1201	994	14	,	,	,
cord-022561-rv5j1201	994	15	and	and	CC
cord-022561-rv5j1201	994	16	petechiae	petechia	NNS
cord-022561-rv5j1201	994	17	on	on	IN
cord-022561-rv5j1201	994	18	serosal	serosal	NN
cord-022561-rv5j1201	994	19	membranes	membrane	NNS
cord-022561-rv5j1201	994	20	.	.	.
cord-022561-rv5j1201	995	1	An	an	DT
cord-022561-rv5j1201	995	2	acute	acute	JJ
cord-022561-rv5j1201	995	3	hemorrhagic	hemorrhagic	JJ
cord-022561-rv5j1201	995	4	syndrome	syndrome	NN
cord-022561-rv5j1201	995	5	may	may	MD
cord-022561-rv5j1201	995	6	occur	occur	VB
cord-022561-rv5j1201	995	7	in	in	IN
cord-022561-rv5j1201	995	8	cattle	cattle	NNS
cord-022561-rv5j1201	995	9	,	,	,
cord-022561-rv5j1201	995	10	resulting	result	VBG
cord-022561-rv5j1201	995	11	in	in	IN
cord-022561-rv5j1201	995	12	lesions	lesion	NNS
cord-022561-rv5j1201	995	13	of	of	IN
cord-022561-rv5j1201	995	14	severe	severe	JJ
cord-022561-rv5j1201	995	15	anemia	anemia	NN
cord-022561-rv5j1201	995	16	(	(	-LRB-
cord-022561-rv5j1201	995	17	e.g.	e.g.	RB
cord-022561-rv5j1201	995	18	,	,	,
cord-022561-rv5j1201	995	19	pale	pale	JJ
cord-022561-rv5j1201	995	20	mucous	mucous	JJ
cord-022561-rv5j1201	995	21	membranes	membrane	NNS
cord-022561-rv5j1201	995	22	)	)	-RRB-
cord-022561-rv5j1201	995	23	and	and	CC
cord-022561-rv5j1201	995	24	widespread	widespread	JJ
cord-022561-rv5j1201	995	25	mucosal	mucosal	JJ
cord-022561-rv5j1201	995	26	and	and	CC
cord-022561-rv5j1201	995	27	visceral	visceral	JJ
cord-022561-rv5j1201	995	28	hemorrhages	hemorrhage	NNS
cord-022561-rv5j1201	995	29	.	.	.
cord-022561-rv5j1201	996	1	Main	main	JJ
cord-022561-rv5j1201	996	2	lesions	lesion	NNS
cord-022561-rv5j1201	996	3	of	of	IN
cord-022561-rv5j1201	996	4	chronic	chronic	JJ
cord-022561-rv5j1201	996	5	infections	infection	NNS
cord-022561-rv5j1201	996	6	include	include	VBP
cord-022561-rv5j1201	996	7	signs	sign	NNS
cord-022561-rv5j1201	996	8	of	of	IN
cord-022561-rv5j1201	996	9	anemia	anemia	NN
cord-022561-rv5j1201	996	10	,	,	,
cord-022561-rv5j1201	996	11	lymphadenopathy	lymphadenopathy	JJ
cord-022561-rv5j1201	996	12	(	(	-LRB-
cord-022561-rv5j1201	996	13	e.g.	e.g.	RB
cord-022561-rv5j1201	996	14	,	,	,
cord-022561-rv5j1201	996	15	enlarged	enlarged	JJ
cord-022561-rv5j1201	996	16	or	or	CC
cord-022561-rv5j1201	996	17	atrophied	atrophy	VBN
cord-022561-rv5j1201	996	18	lymph	lymph	NN
cord-022561-rv5j1201	996	19	nodes	node	NNS
cord-022561-rv5j1201	996	20	)	)	-RRB-
cord-022561-rv5j1201	996	21	,	,	,
cord-022561-rv5j1201	996	22	emaciation	emaciation	NN
cord-022561-rv5j1201	996	23	,	,	,
cord-022561-rv5j1201	996	24	subcutaneous	subcutaneous	JJ
cord-022561-rv5j1201	996	25	edema	edema	NN
cord-022561-rv5j1201	996	26	,	,	,
cord-022561-rv5j1201	996	27	pulmonary	pulmonary	JJ
cord-022561-rv5j1201	996	28	edema	edema	NN
cord-022561-rv5j1201	996	29	,	,	,
cord-022561-rv5j1201	996	30	increased	increase	VBN
cord-022561-rv5j1201	996	31	fluid	fluid	NN
cord-022561-rv5j1201	996	32	in	in	IN
cord-022561-rv5j1201	996	33	body	body	NN
cord-022561-rv5j1201	996	34	cavities	cavity	NNS
cord-022561-rv5j1201	996	35	,	,	,
cord-022561-rv5j1201	996	36	and	and	CC
cord-022561-rv5j1201	996	37	serous	serous	JJ
cord-022561-rv5j1201	996	38	atrophy	atrophy	NN
cord-022561-rv5j1201	996	39	of	of	IN
cord-022561-rv5j1201	996	40	fat	fat	NN
cord-022561-rv5j1201	996	41	.	.	.
cord-022561-rv5j1201	997	1	Trypanosoma	Trypanosoma	NNP
cord-022561-rv5j1201	997	2	cruzi	cruzi	NNP
cord-022561-rv5j1201	997	3	is	be	VBZ
cord-022561-rv5j1201	997	4	the	the	DT
cord-022561-rv5j1201	997	5	flagellated	flagellated	JJ
cord-022561-rv5j1201	997	6	protozoal	protozoal	JJ
cord-022561-rv5j1201	997	7	agent	agent	NN
cord-022561-rv5j1201	997	8	of	of	IN
cord-022561-rv5j1201	997	9	American	american	JJ
cord-022561-rv5j1201	997	10	trypanosomiasis	trypanosomiasis	NN
cord-022561-rv5j1201	997	11	.	.	.
cord-022561-rv5j1201	998	1	Infections	infection	NNS
cord-022561-rv5j1201	998	2	have	have	VBP
cord-022561-rv5j1201	998	3	been	be	VBN
cord-022561-rv5j1201	998	4	reported	report	VBN
cord-022561-rv5j1201	998	5	in	in	IN
cord-022561-rv5j1201	998	6	more	more	JJR
cord-022561-rv5j1201	998	7	than	than	IN
cord-022561-rv5j1201	998	8	100	100	CD
cord-022561-rv5j1201	998	9	mammal	mammal	NN
cord-022561-rv5j1201	998	10	species	specie	NNS
cord-022561-rv5j1201	998	11	in	in	IN
cord-022561-rv5j1201	998	12	South	South	NNP
cord-022561-rv5j1201	998	13	America	America	NNP
cord-022561-rv5j1201	998	14	,	,	,
cord-022561-rv5j1201	998	15	Central	Central	NNP
cord-022561-rv5j1201	998	16	America	America	NNP
cord-022561-rv5j1201	998	17	,	,	,
cord-022561-rv5j1201	998	18	and	and	CC
cord-022561-rv5j1201	998	19	the	the	DT
cord-022561-rv5j1201	998	20	southern	southern	JJ
cord-022561-rv5j1201	998	21	United	United	NNP
cord-022561-rv5j1201	998	22	States	States	NNP
cord-022561-rv5j1201	998	23	,	,	,
cord-022561-rv5j1201	998	24	but	but	CC
cord-022561-rv5j1201	998	25	dogs	dog	NNS
cord-022561-rv5j1201	998	26	and	and	CC
cord-022561-rv5j1201	998	27	cats	cat	NNS
cord-022561-rv5j1201	998	28	are	be	VBP
cord-022561-rv5j1201	998	29	among	among	IN
cord-022561-rv5j1201	998	30	the	the	DT
cord-022561-rv5j1201	998	31	more	more	RBR
cord-022561-rv5j1201	998	32	common	common	JJ
cord-022561-rv5j1201	998	33	domestic	domestic	JJ
cord-022561-rv5j1201	998	34	hosts	host	NNS
cord-022561-rv5j1201	998	35	.	.	.
cord-022561-rv5j1201	999	1	Infected	infected	JJ
cord-022561-rv5j1201	999	2	triatomine	triatomine	JJ
cord-022561-rv5j1201	999	3	insects	insect	NNS
cord-022561-rv5j1201	999	4	,	,	,
cord-022561-rv5j1201	999	5	or	or	CC
cord-022561-rv5j1201	999	6	"	"	``
cord-022561-rv5j1201	999	7	kissing	kiss	VBG
cord-022561-rv5j1201	999	8	bugs	bug	NNS
cord-022561-rv5j1201	999	9	,	,	,
cord-022561-rv5j1201	999	10	"	"	''
cord-022561-rv5j1201	999	11	defecate	defecate	VB
cord-022561-rv5j1201	999	12	as	as	IN
cord-022561-rv5j1201	999	13	they	-PRON-	PRP
cord-022561-rv5j1201	999	14	feed	feed	VBP
cord-022561-rv5j1201	999	15	on	on	IN
cord-022561-rv5j1201	999	16	their	-PRON-	PRP$
cord-022561-rv5j1201	999	17	mammalian	mammalian	JJ
cord-022561-rv5j1201	999	18	host	host	NN
cord-022561-rv5j1201	999	19	,	,	,
cord-022561-rv5j1201	999	20	releasing	release	VBG
cord-022561-rv5j1201	999	21	infective	infective	JJ
cord-022561-rv5j1201	999	22	T.	T.	NNP
cord-022561-rv5j1201	999	23	cruzi	cruzi	NN
cord-022561-rv5j1201	999	24	organisms	organism	NNS
cord-022561-rv5j1201	999	25	.	.	.
cord-022561-rv5j1201	1000	1	The	the	DT
cord-022561-rv5j1201	1000	2	parasite	parasite	NN
cord-022561-rv5j1201	1000	3	then	then	RB
cord-022561-rv5j1201	1000	4	enters	enter	VBZ
cord-022561-rv5j1201	1000	5	the	the	DT
cord-022561-rv5j1201	1000	6	body	body	NN
cord-022561-rv5j1201	1000	7	through	through	IN
cord-022561-rv5j1201	1000	8	mucous	mucous	JJ
cord-022561-rv5j1201	1000	9	membranes	membrane	NNS
cord-022561-rv5j1201	1000	10	or	or	CC
cord-022561-rv5j1201	1000	11	breaks	break	NNS
cord-022561-rv5j1201	1000	12	in	in	IN
cord-022561-rv5j1201	1000	13	the	the	DT
cord-022561-rv5j1201	1000	14	skin	skin	NN
cord-022561-rv5j1201	1000	15	.	.	.
cord-022561-rv5j1201	1001	1	Like	like	IN
cord-022561-rv5j1201	1001	2	the	the	DT
cord-022561-rv5j1201	1001	3	other	other	JJ
cord-022561-rv5j1201	1001	4	trypanosomes	trypanosome	NNS
cord-022561-rv5j1201	1001	5	described	describe	VBN
cord-022561-rv5j1201	1001	6	previously	previously	RB
cord-022561-rv5j1201	1001	7	,	,	,
cord-022561-rv5j1201	1001	8	T.	T.	NNP
cord-022561-rv5j1201	1001	9	cruzi	cruzi	NNP
cord-022561-rv5j1201	1001	10	lives	live	VBZ
cord-022561-rv5j1201	1001	11	in	in	IN
cord-022561-rv5j1201	1001	12	the	the	DT
cord-022561-rv5j1201	1001	13	blood	blood	NN
cord-022561-rv5j1201	1001	14	as	as	IN
cord-022561-rv5j1201	1001	15	extracellular	extracellular	JJ
cord-022561-rv5j1201	1001	16	trypomastigotes	trypomastigote	NNS
cord-022561-rv5j1201	1001	17	(	(	-LRB-
cord-022561-rv5j1201	1001	18	see	see	VB
cord-022561-rv5j1201	1001	19	Fig	Fig	NNP
cord-022561-rv5j1201	1001	20	.	.	.
cord-022561-rv5j1201	1001	21	 	 	_SP
cord-022561-rv5j1201	1002	1	13	13	CD
cord-022561-rv5j1201	1002	2	-25	-25	NN
cord-022561-rv5j1201	1002	3	,	,	,
cord-022561-rv5j1201	1002	4	B	B	NNP
cord-022561-rv5j1201	1002	5	)	)	-RRB-
cord-022561-rv5j1201	1002	6	and	and	CC
cord-022561-rv5j1201	1002	7	in	in	IN
cord-022561-rv5j1201	1002	8	the	the	DT
cord-022561-rv5j1201	1002	9	tissues	tissue	NNS
cord-022561-rv5j1201	1002	10	as	as	IN
cord-022561-rv5j1201	1002	11	intracellular	intracellular	JJ
cord-022561-rv5j1201	1002	12	amastigotes	amastigote	NNS
cord-022561-rv5j1201	1002	13	.	.	.
cord-022561-rv5j1201	1003	1	Trypanosoma	Trypanosoma	NNP
cord-022561-rv5j1201	1003	2	cruzi	cruzi	VBP
cord-022561-rv5j1201	1003	3	primarily	primarily	RB
cord-022561-rv5j1201	1003	4	causes	cause	VBZ
cord-022561-rv5j1201	1003	5	heart	heart	NN
cord-022561-rv5j1201	1003	6	disease	disease	NN
cord-022561-rv5j1201	1003	7	.	.	.
cord-022561-rv5j1201	1004	1	Lesions	lesion	NNS
cord-022561-rv5j1201	1004	2	of	of	IN
cord-022561-rv5j1201	1004	3	acute	acute	JJ
cord-022561-rv5j1201	1004	4	disease	disease	NN
cord-022561-rv5j1201	1004	5	include	include	VBP
cord-022561-rv5j1201	1004	6	a	a	DT
cord-022561-rv5j1201	1004	7	pale	pale	JJ
cord-022561-rv5j1201	1004	8	myocardium	myocardium	NN
cord-022561-rv5j1201	1004	9	,	,	,
cord-022561-rv5j1201	1004	10	subendocardial	subendocardial	JJ
cord-022561-rv5j1201	1004	11	and	and	CC
cord-022561-rv5j1201	1004	12	subepicardial	subepicardial	JJ
cord-022561-rv5j1201	1004	13	hemorrhages	hemorrhage	NNS
cord-022561-rv5j1201	1004	14	,	,	,
cord-022561-rv5j1201	1004	15	and	and	CC
cord-022561-rv5j1201	1004	16	yellowish	yellowish	JJ
cord-022561-rv5j1201	1004	17	-	-	HYPH
cord-022561-rv5j1201	1004	18	white	white	JJ
cord-022561-rv5j1201	1004	19	spots	spot	NNS
cord-022561-rv5j1201	1004	20	and	and	CC
cord-022561-rv5j1201	1004	21	streaks	streak	NNS
cord-022561-rv5j1201	1004	22	.	.	.
cord-022561-rv5j1201	1005	1	There	there	EX
cord-022561-rv5j1201	1005	2	may	may	MD
cord-022561-rv5j1201	1005	3	also	also	RB
cord-022561-rv5j1201	1005	4	be	be	VB
cord-022561-rv5j1201	1005	5	secondary	secondary	JJ
cord-022561-rv5j1201	1005	6	lesions	lesion	NNS
cord-022561-rv5j1201	1005	7	,	,	,
cord-022561-rv5j1201	1005	8	such	such	JJ
cord-022561-rv5j1201	1005	9	as	as	IN
cord-022561-rv5j1201	1005	10	pulmonary	pulmonary	JJ
cord-022561-rv5j1201	1005	11	edema	edema	NN
cord-022561-rv5j1201	1005	12	,	,	,
cord-022561-rv5j1201	1005	13	ascites	ascites	NN
cord-022561-rv5j1201	1005	14	,	,	,
cord-022561-rv5j1201	1005	15	and	and	CC
cord-022561-rv5j1201	1005	16	congestion	congestion	NN
cord-022561-rv5j1201	1005	17	of	of	IN
cord-022561-rv5j1201	1005	18	the	the	DT
cord-022561-rv5j1201	1005	19	liver	liver	NN
cord-022561-rv5j1201	1005	20	,	,	,
cord-022561-rv5j1201	1005	21	spleen	spleen	NNS
cord-022561-rv5j1201	1005	22	,	,	,
cord-022561-rv5j1201	1005	23	and	and	CC
cord-022561-rv5j1201	1005	24	kidneys	kidney	NNS
cord-022561-rv5j1201	1005	25	.	.	.
cord-022561-rv5j1201	1006	1	In	in	IN
cord-022561-rv5j1201	1006	2	chronic	chronic	JJ
cord-022561-rv5j1201	1006	3	disease	disease	NN
cord-022561-rv5j1201	1006	4	the	the	DT
cord-022561-rv5j1201	1006	5	heart	heart	NN
cord-022561-rv5j1201	1006	6	may	may	MD
cord-022561-rv5j1201	1006	7	be	be	VB
cord-022561-rv5j1201	1006	8	enlarged	enlarge	VBN
cord-022561-rv5j1201	1006	9	and	and	CC
cord-022561-rv5j1201	1006	10	flaccid	flaccid	JJ
cord-022561-rv5j1201	1006	11	with	with	IN
cord-022561-rv5j1201	1006	12	thin	thin	JJ
cord-022561-rv5j1201	1006	13	walls	wall	NNS
cord-022561-rv5j1201	1006	14	.	.	.
cord-022561-rv5j1201	1007	1	Microscopically	microscopically	RB
cord-022561-rv5j1201	1007	2	,	,	,
cord-022561-rv5j1201	1007	3	there	there	EX
cord-022561-rv5j1201	1007	4	is	be	VBZ
cord-022561-rv5j1201	1007	5	often	often	RB
cord-022561-rv5j1201	1007	6	myocarditis	myocarditis	NN
cord-022561-rv5j1201	1007	7	and	and	CC
cord-022561-rv5j1201	1007	8	amastigotes	amastigote	NNS
cord-022561-rv5j1201	1007	9	within	within	IN
cord-022561-rv5j1201	1007	10	cardiomyocytes	cardiomyocyte	NNS
cord-022561-rv5j1201	1007	11	.	.	.
cord-022561-rv5j1201	1007	12	 	 	_SP
cord-022561-rv5j1201	1008	1	Most	Most	JJS
cord-022561-rv5j1201	1008	2	of	of	IN
cord-022561-rv5j1201	1008	3	these	these	DT
cord-022561-rv5j1201	1008	4	rickettsias	rickettsia	NNS
cord-022561-rv5j1201	1008	5	have	have	VBP
cord-022561-rv5j1201	1008	6	worldwide	worldwide	JJ
cord-022561-rv5j1201	1008	7	distributions	distribution	NNS
cord-022561-rv5j1201	1008	8	.	.	.
cord-022561-rv5j1201	1009	1	However	however	RB
cord-022561-rv5j1201	1009	2	,	,	,
cord-022561-rv5j1201	1009	3	E.	E.	NNP
cord-022561-rv5j1201	1009	4	ewingii	ewingii	NNP
cord-022561-rv5j1201	1009	5	has	have	VBZ
cord-022561-rv5j1201	1009	6	been	be	VBN
cord-022561-rv5j1201	1009	7	reported	report	VBN
cord-022561-rv5j1201	1009	8	only	only	RB
cord-022561-rv5j1201	1009	9	in	in	IN
cord-022561-rv5j1201	1009	10	the	the	DT
cord-022561-rv5j1201	1009	11	United	United	NNP
cord-022561-rv5j1201	1009	12	States	States	NNP
cord-022561-rv5j1201	1009	13	,	,	,
cord-022561-rv5j1201	1009	14	and	and	CC
cord-022561-rv5j1201	1009	15	E.	E.	NNP
cord-022561-rv5j1201	1009	16	ruminantium	ruminantium	NNP
cord-022561-rv5j1201	1009	17	is	be	VBZ
cord-022561-rv5j1201	1009	18	endemic	endemic	JJ
cord-022561-rv5j1201	1009	19	only	only	RB
cord-022561-rv5j1201	1009	20	in	in	IN
cord-022561-rv5j1201	1009	21	parts	part	NNS
cord-022561-rv5j1201	1009	22	of	of	IN
cord-022561-rv5j1201	1009	23	Africa	Africa	NNP
cord-022561-rv5j1201	1009	24	and	and	CC
cord-022561-rv5j1201	1009	25	the	the	DT
cord-022561-rv5j1201	1009	26	Caribbean	Caribbean	NNP
cord-022561-rv5j1201	1009	27	.	.	.
cord-022561-rv5j1201	1010	1	Although	although	IN
cord-022561-rv5j1201	1010	2	A.	A.	NNP
cord-022561-rv5j1201	1010	3	phagocytophilum	phagocytophilum	NN
cord-022561-rv5j1201	1010	4	has	have	VBZ
cord-022561-rv5j1201	1010	5	a	a	DT
cord-022561-rv5j1201	1010	6	wide	wide	JJ
cord-022561-rv5j1201	1010	7	geographic	geographic	JJ
cord-022561-rv5j1201	1010	8	distribution	distribution	NN
cord-022561-rv5j1201	1010	9	,	,	,
cord-022561-rv5j1201	1010	10	strain	strain	NN
cord-022561-rv5j1201	1010	11	variants	variant	NNS
cord-022561-rv5j1201	1010	12	are	be	VBP
cord-022561-rv5j1201	1010	13	regionally	regionally	RB
cord-022561-rv5j1201	1010	14	restricted	restrict	VBN
cord-022561-rv5j1201	1010	15	.	.	.
cord-022561-rv5j1201	1011	1	For	for	IN
cord-022561-rv5j1201	1011	2	example	example	NN
cord-022561-rv5j1201	1011	3	,	,	,
cord-022561-rv5j1201	1011	4	A.	a.	NN
cord-022561-rv5j1201	1011	5	phagocytophilum	phagocytophilum	NN
cord-022561-rv5j1201	1011	6	causes	cause	VBZ
cord-022561-rv5j1201	1011	7	disease	disease	NN
cord-022561-rv5j1201	1011	8	in	in	IN
cord-022561-rv5j1201	1011	9	ruminants	ruminant	NNS
cord-022561-rv5j1201	1011	10	in	in	IN
cord-022561-rv5j1201	1011	11	Europe	Europe	NNP
cord-022561-rv5j1201	1011	12	,	,	,
cord-022561-rv5j1201	1011	13	but	but	CC
cord-022561-rv5j1201	1011	14	it	-PRON-	PRP
cord-022561-rv5j1201	1011	15	has	have	VBZ
cord-022561-rv5j1201	1011	16	not	not	RB
cord-022561-rv5j1201	1011	17	been	be	VBN
cord-022561-rv5j1201	1011	18	documented	document	VBN
cord-022561-rv5j1201	1011	19	in	in	IN
cord-022561-rv5j1201	1011	20	ruminants	ruminant	NNS
cord-022561-rv5j1201	1011	21	in	in	IN
cord-022561-rv5j1201	1011	22	the	the	DT
cord-022561-rv5j1201	1011	23	United	United	NNP
cord-022561-rv5j1201	1011	24	States	States	NNP
cord-022561-rv5j1201	1011	25	.	.	.
cord-022561-rv5j1201	1012	1	Reservoirs	reservoir	NNS
cord-022561-rv5j1201	1012	2	of	of	IN
cord-022561-rv5j1201	1012	3	disease	disease	NN
cord-022561-rv5j1201	1012	4	vary	vary	VBP
cord-022561-rv5j1201	1012	5	,	,	,
cord-022561-rv5j1201	1012	6	depending	depend	VBG
cord-022561-rv5j1201	1012	7	upon	upon	IN
cord-022561-rv5j1201	1012	8	the	the	DT
cord-022561-rv5j1201	1012	9	rickettsial	rickettsial	JJ
cord-022561-rv5j1201	1012	10	species	specie	NNS
cord-022561-rv5j1201	1012	11	.	.	.
cord-022561-rv5j1201	1013	1	Cattle	Cattle	NNS
cord-022561-rv5j1201	1013	2	are	be	VBP
cord-022561-rv5j1201	1013	3	the	the	DT
cord-022561-rv5j1201	1013	4	reservoir	reservoir	NN
cord-022561-rv5j1201	1013	5	host	host	NN
cord-022561-rv5j1201	1013	6	for	for	IN
cord-022561-rv5j1201	1013	7	E.	E.	NNP
cord-022561-rv5j1201	1013	8	ruminantium	ruminantium	NNP
cord-022561-rv5j1201	1013	9	,	,	,
cord-022561-rv5j1201	1013	10	canids	canid	NNS
cord-022561-rv5j1201	1013	11	are	be	VBP
cord-022561-rv5j1201	1013	12	the	the	DT
cord-022561-rv5j1201	1013	13	reservoir	reservoir	NN
cord-022561-rv5j1201	1013	14	host	host	NN
cord-022561-rv5j1201	1013	15	for	for	IN
cord-022561-rv5j1201	1013	16	A.	a.	NN
cord-022561-rv5j1201	1013	17	platys	platy	NNS
cord-022561-rv5j1201	1013	18	and	and	CC
cord-022561-rv5j1201	1013	19	E.	E.	NNP
cord-022561-rv5j1201	1013	20	canis	canis	NNP
cord-022561-rv5j1201	1013	21	,	,	,
cord-022561-rv5j1201	1013	22	and	and	CC
cord-022561-rv5j1201	1013	23	the	the	DT
cord-022561-rv5j1201	1013	24	other	other	JJ
cord-022561-rv5j1201	1013	25	rickettsias	rickettsia	NNS
cord-022561-rv5j1201	1013	26	have	have	VBP
cord-022561-rv5j1201	1013	27	wildlife	wildlife	NN
cord-022561-rv5j1201	1013	28	reservoirs	reservoir	NNS
cord-022561-rv5j1201	1013	29	.	.	.
cord-022561-rv5j1201	1014	1	Pathogenesis	pathogenesis	NN
cord-022561-rv5j1201	1014	2	of	of	IN
cord-022561-rv5j1201	1014	3	disease	disease	NN
cord-022561-rv5j1201	1014	4	involves	involve	VBZ
cord-022561-rv5j1201	1014	5	endothelial	endothelial	JJ
cord-022561-rv5j1201	1014	6	cell	cell	NN
cord-022561-rv5j1201	1014	7	,	,	,
cord-022561-rv5j1201	1014	8	platelet	platelet	NN
cord-022561-rv5j1201	1014	9	,	,	,
cord-022561-rv5j1201	1014	10	and	and	CC
cord-022561-rv5j1201	1014	11	leukocyte	leukocyte	NN
cord-022561-rv5j1201	1014	12	dysfunction	dysfunction	NN
cord-022561-rv5j1201	1014	13	.	.	.
cord-022561-rv5j1201	1015	1	Those	those	DT
cord-022561-rv5j1201	1015	2	agents	agent	NNS
cord-022561-rv5j1201	1015	3	that	that	WDT
cord-022561-rv5j1201	1015	4	infect	infect	VBP
cord-022561-rv5j1201	1015	5	endothelial	endothelial	JJ
cord-022561-rv5j1201	1015	6	cells	cell	NNS
cord-022561-rv5j1201	1015	7	cause	cause	VBP
cord-022561-rv5j1201	1015	8	vasculitis	vasculitis	NN
cord-022561-rv5j1201	1015	9	and	and	CC
cord-022561-rv5j1201	1015	10	increased	increase	VBD
cord-022561-rv5j1201	1015	11	vascular	vascular	JJ
cord-022561-rv5j1201	1015	12	permeability	permeability	NN
cord-022561-rv5j1201	1015	13	of	of	IN
cord-022561-rv5j1201	1015	14	small	small	JJ
cord-022561-rv5j1201	1015	15	blood	blood	NN
cord-022561-rv5j1201	1015	16	vessels	vessel	NNS
cord-022561-rv5j1201	1015	17	.	.	.
cord-022561-rv5j1201	1016	1	If	if	IN
cord-022561-rv5j1201	1016	2	only	only	JJ
cord-022561-rv5j1201	1016	3	plasma	plasma	NN
cord-022561-rv5j1201	1016	4	is	be	VBZ
cord-022561-rv5j1201	1016	5	lost	lose	VBN
cord-022561-rv5j1201	1016	6	,	,	,
cord-022561-rv5j1201	1016	7	then	then	RB
cord-022561-rv5j1201	1016	8	there	there	EX
cord-022561-rv5j1201	1016	9	is	be	VBZ
cord-022561-rv5j1201	1016	10	hypotension	hypotension	NN
cord-022561-rv5j1201	1016	11	and	and	CC
cord-022561-rv5j1201	1016	12	tissue	tissue	NN
cord-022561-rv5j1201	1016	13	edema	edema	NN
cord-022561-rv5j1201	1016	14	.	.	.
cord-022561-rv5j1201	1017	1	However	however	RB
cord-022561-rv5j1201	1017	2	,	,	,
cord-022561-rv5j1201	1017	3	more	more	RBR
cord-022561-rv5j1201	1017	4	severe	severe	JJ
cord-022561-rv5j1201	1017	5	vasculitis	vasculitis	NN
cord-022561-rv5j1201	1017	6	causes	cause	VBZ
cord-022561-rv5j1201	1017	7	microvascular	microvascular	JJ
cord-022561-rv5j1201	1017	8	hemorrhage	hemorrhage	NN
cord-022561-rv5j1201	1017	9	with	with	IN
cord-022561-rv5j1201	1017	10	the	the	DT
cord-022561-rv5j1201	1017	11	potential	potential	NN
cord-022561-rv5j1201	1017	12	for	for	IN
cord-022561-rv5j1201	1017	13	platelet	platelet	NN
cord-022561-rv5j1201	1017	14	consumption	consumption	NN
cord-022561-rv5j1201	1017	15	thrombocytopenia	thrombocytopenia	NN
cord-022561-rv5j1201	1017	16	,	,	,
cord-022561-rv5j1201	1017	17	disseminated	disseminate	VBN
cord-022561-rv5j1201	1017	18	intravascular	intravascular	JJ
cord-022561-rv5j1201	1017	19	coagulation	coagulation	NN
cord-022561-rv5j1201	1017	20	,	,	,
cord-022561-rv5j1201	1017	21	and	and	CC
cord-022561-rv5j1201	1017	22	hypotension	hypotension	NN
cord-022561-rv5j1201	1017	23	.	.	.
cord-022561-rv5j1201	1018	1	Infection	infection	NN
cord-022561-rv5j1201	1018	2	of	of	IN
cord-022561-rv5j1201	1018	3	platelets	platelet	NNS
cord-022561-rv5j1201	1018	4	may	may	MD
cord-022561-rv5j1201	1018	5	cause	cause	VB
cord-022561-rv5j1201	1018	6	thrombocytopenia	thrombocytopenia	NN
cord-022561-rv5j1201	1018	7	by	by	IN
cord-022561-rv5j1201	1018	8	direct	direct	JJ
cord-022561-rv5j1201	1018	9	platelet	platelet	NN
cord-022561-rv5j1201	1018	10	lysis	lysis	NN
cord-022561-rv5j1201	1018	11	,	,	,
cord-022561-rv5j1201	1018	12	immune	immune	NN
cord-022561-rv5j1201	1018	13	-	-	HYPH
cord-022561-rv5j1201	1018	14	mediated	mediate	VBN
cord-022561-rv5j1201	1018	15	mechanisms	mechanism	NNS
cord-022561-rv5j1201	1018	16	,	,	,
cord-022561-rv5j1201	1018	17	or	or	CC
cord-022561-rv5j1201	1018	18	platelet	platelet	NN
cord-022561-rv5j1201	1018	19	sequestration	sequestration	NN
cord-022561-rv5j1201	1018	20	within	within	IN
cord-022561-rv5j1201	1018	21	the	the	DT
cord-022561-rv5j1201	1018	22	spleen	spleen	NN
cord-022561-rv5j1201	1018	23	.	.	.
cord-022561-rv5j1201	1019	1	Pathogenesis	pathogenesis	NN
cord-022561-rv5j1201	1019	2	of	of	IN
cord-022561-rv5j1201	1019	3	leukocyte	leukocyte	NN
cord-022561-rv5j1201	1019	4	dysfunction	dysfunction	NN
cord-022561-rv5j1201	1019	5	is	be	VBZ
cord-022561-rv5j1201	1019	6	unclear	unclear	JJ
cord-022561-rv5j1201	1019	7	,	,	,
cord-022561-rv5j1201	1019	8	but	but	CC
cord-022561-rv5j1201	1019	9	may	may	MD
cord-022561-rv5j1201	1019	10	involve	involve	VB
cord-022561-rv5j1201	1019	11	sepsis	sepsis	NN
cord-022561-rv5j1201	1019	12	,	,	,
cord-022561-rv5j1201	1019	13	inhibited	inhibited	JJ
cord-022561-rv5j1201	1019	14	leukocyte	leukocyte	NN
cord-022561-rv5j1201	1019	15	function	function	NN
cord-022561-rv5j1201	1019	16	,	,	,
cord-022561-rv5j1201	1019	17	endothelial	endothelial	JJ
cord-022561-rv5j1201	1019	18	cell	cell	NN
cord-022561-rv5j1201	1019	19	activation	activation	NN
cord-022561-rv5j1201	1019	20	,	,	,
cord-022561-rv5j1201	1019	21	and	and	CC
cord-022561-rv5j1201	1019	22	platelet	platelet	NN
cord-022561-rv5j1201	1019	23	consumption	consumption	NN
cord-022561-rv5j1201	1019	24	.	.	.
cord-022561-rv5j1201	1020	1	Chronic	Chronic	NNP
cord-022561-rv5j1201	1020	2	E.	E.	NNP
cord-022561-rv5j1201	1020	3	canis	canis	NN
cord-022561-rv5j1201	1020	4	infection	infection	NN
cord-022561-rv5j1201	1020	5	may	may	MD
cord-022561-rv5j1201	1020	6	cause	cause	VB
cord-022561-rv5j1201	1020	7	aplastic	aplastic	JJ
cord-022561-rv5j1201	1020	8	anemia	anemia	NN
cord-022561-rv5j1201	1020	9	with	with	IN
cord-022561-rv5j1201	1020	10	pancytopenia	pancytopenia	NNP
cord-022561-rv5j1201	1020	11	by	by	IN
cord-022561-rv5j1201	1020	12	an	an	DT
cord-022561-rv5j1201	1020	13	unknown	unknown	JJ
cord-022561-rv5j1201	1020	14	mechanism	mechanism	NN
cord-022561-rv5j1201	1020	15	.	.	.
cord-022561-rv5j1201	1021	1	Some	some	DT
cord-022561-rv5j1201	1021	2	studies	study	NNS
cord-022561-rv5j1201	1021	3	indicate	indicate	VBP
cord-022561-rv5j1201	1021	4	that	that	IN
cord-022561-rv5j1201	1021	5	German	german	JJ
cord-022561-rv5j1201	1021	6	shepherd	shepherd	NN
cord-022561-rv5j1201	1021	7	dogs	dog	NNS
cord-022561-rv5j1201	1021	8	with	with	IN
cord-022561-rv5j1201	1021	9	ehrlichiosis	ehrlichiosis	NNP
cord-022561-rv5j1201	1021	10	are	be	VBP
cord-022561-rv5j1201	1021	11	predisposed	predisposed	JJ
cord-022561-rv5j1201	1021	12	to	to	TO
cord-022561-rv5j1201	1021	13	have	have	VB
cord-022561-rv5j1201	1021	14	particularly	particularly	RB
cord-022561-rv5j1201	1021	15	severe	severe	JJ
cord-022561-rv5j1201	1021	16	clinical	clinical	JJ
cord-022561-rv5j1201	1021	17	disease	disease	NN
cord-022561-rv5j1201	1021	18	.	.	.
cord-022561-rv5j1201	1022	1	Some	some	DT
cord-022561-rv5j1201	1022	2	breeds	breed	NNS
cord-022561-rv5j1201	1022	3	of	of	IN
cord-022561-rv5j1201	1022	4	cattle	cattle	NNS
cord-022561-rv5j1201	1022	5	(	(	-LRB-
cord-022561-rv5j1201	1022	6	Bos	Bos	NNP
cord-022561-rv5j1201	1022	7	taurus	taurus	NNP
cord-022561-rv5j1201	1022	8	)	)	-RRB-
cord-022561-rv5j1201	1022	9	,	,	,
cord-022561-rv5j1201	1022	10	sheep	sheep	NNP
cord-022561-rv5j1201	1022	11	(	(	-LRB-
cord-022561-rv5j1201	1022	12	merino	merino	NNP
cord-022561-rv5j1201	1022	13	)	)	-RRB-
cord-022561-rv5j1201	1022	14	,	,	,
cord-022561-rv5j1201	1022	15	and	and	CC
cord-022561-rv5j1201	1022	16	goats	goat	NNS
cord-022561-rv5j1201	1022	17	(	(	-LRB-
cord-022561-rv5j1201	1022	18	Angora	Angora	NNP
cord-022561-rv5j1201	1022	19	and	and	CC
cord-022561-rv5j1201	1022	20	Saanen	Saanen	NNP
cord-022561-rv5j1201	1022	21	)	)	-RRB-
cord-022561-rv5j1201	1022	22	are	be	VBP
cord-022561-rv5j1201	1022	23	more	more	RBR
cord-022561-rv5j1201	1022	24	susceptible	susceptible	JJ
cord-022561-rv5j1201	1022	25	to	to	IN
cord-022561-rv5j1201	1022	26	heartwater	heartwater	NNP
cord-022561-rv5j1201	1022	27	.	.	.
cord-022561-rv5j1201	1023	1	Upon	upon	IN
cord-022561-rv5j1201	1023	2	blood	blood	NN
cord-022561-rv5j1201	1023	3	smear	smear	NN
cord-022561-rv5j1201	1023	4	evaluation	evaluation	NN
cord-022561-rv5j1201	1023	5	,	,	,
cord-022561-rv5j1201	1023	6	thrombocytopenia	thrombocytopenia	NN
cord-022561-rv5j1201	1023	7	is	be	VBZ
cord-022561-rv5j1201	1023	8	the	the	DT
cord-022561-rv5j1201	1023	9	most	most	RBS
cord-022561-rv5j1201	1023	10	common	common	JJ
cord-022561-rv5j1201	1023	11	hematologic	hematologic	JJ
cord-022561-rv5j1201	1023	12	abnormality	abnormality	NN
cord-022561-rv5j1201	1023	13	;	;	:
cord-022561-rv5j1201	1023	14	anemia	anemia	NN
cord-022561-rv5j1201	1023	15	and	and	CC
cord-022561-rv5j1201	1023	16	neutropenia	neutropenia	NN
cord-022561-rv5j1201	1023	17	occur	occur	VBP
cord-022561-rv5j1201	1023	18	less	less	RBR
cord-022561-rv5j1201	1023	19	frequently	frequently	RB
cord-022561-rv5j1201	1023	20	.	.	.
cord-022561-rv5j1201	1024	1	In	in	IN
cord-022561-rv5j1201	1024	2	early	early	JJ
cord-022561-rv5j1201	1024	3	stages	stage	NNS
cord-022561-rv5j1201	1024	4	of	of	IN
cord-022561-rv5j1201	1024	5	infection	infection	NN
cord-022561-rv5j1201	1024	6	,	,	,
cord-022561-rv5j1201	1024	7	blood	blood	NN
cord-022561-rv5j1201	1024	8	cells	cell	NNS
cord-022561-rv5j1201	1024	9	may	may	MD
cord-022561-rv5j1201	1024	10	contain	contain	VB
cord-022561-rv5j1201	1024	11	morulae	morulae	NNP
cord-022561-rv5j1201	1024	12	,	,	,
cord-022561-rv5j1201	1024	13	which	which	WDT
cord-022561-rv5j1201	1024	14	are	be	VBP
cord-022561-rv5j1201	1024	15	clusters	cluster	NNS
cord-022561-rv5j1201	1024	16	of	of	IN
cord-022561-rv5j1201	1024	17	rickettsial	rickettsial	JJ
cord-022561-rv5j1201	1024	18	organisms	organism	NNS
cord-022561-rv5j1201	1024	19	within	within	IN
cord-022561-rv5j1201	1024	20	cytoplasmic	cytoplasmic	JJ
cord-022561-rv5j1201	1024	21	,	,	,
cord-022561-rv5j1201	1024	22	membrane	membrane	NN
cord-022561-rv5j1201	1024	23	-	-	HYPH
cord-022561-rv5j1201	1024	24	bound	bind	VBN
cord-022561-rv5j1201	1024	25	vacuoles	vacuole	NNS
cord-022561-rv5j1201	1024	26	(	(	-LRB-
cord-022561-rv5j1201	1024	27	Fig	Fig	NNP
cord-022561-rv5j1201	1024	28	.	.	.
cord-022561-rv5j1201	1024	29	13	13	CD
cord-022561-rv5j1201	1024	30	-	-	SYM
cord-022561-rv5j1201	1024	31	27	27	CD
cord-022561-rv5j1201	1024	32	)	)	-RRB-
cord-022561-rv5j1201	1024	33	.	.	.
cord-022561-rv5j1201	1025	1	Examination	examination	NN
cord-022561-rv5j1201	1025	2	of	of	IN
cord-022561-rv5j1201	1025	3	buffy	buffy	NNP
cord-022561-rv5j1201	1025	4	coat	coat	NN
cord-022561-rv5j1201	1025	5	smears	smear	VBZ
cord-022561-rv5j1201	1025	6	increases	increase	VBZ
cord-022561-rv5j1201	1025	7	the	the	DT
cord-022561-rv5j1201	1025	8	probability	probability	NN
cord-022561-rv5j1201	1025	9	of	of	IN
cord-022561-rv5j1201	1025	10	detecting	detect	VBG
cord-022561-rv5j1201	1025	11	the	the	DT
cord-022561-rv5j1201	1025	12	organism	organism	NN
cord-022561-rv5j1201	1025	13	.	.	.
cord-022561-rv5j1201	1026	1	Chronic	chronic	JJ
cord-022561-rv5j1201	1026	2	infection	infection	NN
cord-022561-rv5j1201	1026	3	may	may	MD
cord-022561-rv5j1201	1026	4	cause	cause	VB
cord-022561-rv5j1201	1026	5	lymphocytosis	lymphocytosis	NNP
cord-022561-rv5j1201	1026	6	,	,	,
cord-022561-rv5j1201	1026	7	particularly	particularly	RB
cord-022561-rv5j1201	1026	8	of	of	IN
cord-022561-rv5j1201	1026	9	granular	granular	JJ
cord-022561-rv5j1201	1026	10	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	1026	11	.	.	.
cord-022561-rv5j1201	1027	1	Anaplasma	anaplasma	NN
cord-022561-rv5j1201	1027	2	platys	platy	NNS
cord-022561-rv5j1201	1027	3	causes	cause	VBZ
cord-022561-rv5j1201	1027	4	recurrent	recurrent	JJ
cord-022561-rv5j1201	1027	5	marked	mark	VBN
cord-022561-rv5j1201	1027	6	thrombocytopenia	thrombocytopenia	NN
cord-022561-rv5j1201	1027	7	.	.	.
cord-022561-rv5j1201	1028	1	In	in	IN
cord-022561-rv5j1201	1028	2	general	general	JJ
cord-022561-rv5j1201	1028	3	,	,	,
cord-022561-rv5j1201	1028	4	more	more	RBR
cord-022561-rv5j1201	1028	5	common	common	JJ
cord-022561-rv5j1201	1028	6	gross	gross	JJ
cord-022561-rv5j1201	1028	7	lesions	lesion	NNS
cord-022561-rv5j1201	1028	8	are	be	VBP
cord-022561-rv5j1201	1028	9	splenomegaly	splenomegaly	JJ
cord-022561-rv5j1201	1028	10	,	,	,
cord-022561-rv5j1201	1028	11	lymphadenomegaly	lymphadenomegaly	NNP
cord-022561-rv5j1201	1028	12	,	,	,
cord-022561-rv5j1201	1028	13	and	and	CC
cord-022561-rv5j1201	1028	14	pulmonary	pulmonary	JJ
cord-022561-rv5j1201	1028	15	edema	edema	NN
cord-022561-rv5j1201	1028	16	and	and	CC
cord-022561-rv5j1201	1028	17	hemorrhage	hemorrhage	NN
cord-022561-rv5j1201	1028	18	.	.	.
cord-022561-rv5j1201	1029	1	More	More	JJR
cord-022561-rv5j1201	1029	2	severe	severe	JJ
cord-022561-rv5j1201	1029	3	cases	case	NNS
cord-022561-rv5j1201	1029	4	may	may	MD
cord-022561-rv5j1201	1029	5	also	also	RB
cord-022561-rv5j1201	1029	6	exhibit	exhibit	VB
cord-022561-rv5j1201	1029	7	multisystemic	multisystemic	JJ
cord-022561-rv5j1201	1029	8	petechiae	petechia	NNS
cord-022561-rv5j1201	1029	9	,	,	,
cord-022561-rv5j1201	1029	10	ecchymoses	ecchymosis	NNS
cord-022561-rv5j1201	1029	11	,	,	,
cord-022561-rv5j1201	1029	12	and	and	CC
cord-022561-rv5j1201	1029	13	Bovine	bovine	JJ
cord-022561-rv5j1201	1029	14	anaplasmosis	anaplasmosis	NN
cord-022561-rv5j1201	1029	15	causes	cause	VBZ
cord-022561-rv5j1201	1029	16	anemia	anemia	NN
cord-022561-rv5j1201	1029	17	mainly	mainly	RB
cord-022561-rv5j1201	1029	18	by	by	IN
cord-022561-rv5j1201	1029	19	immune	immune	NN
cord-022561-rv5j1201	1029	20	-	-	HYPH
cord-022561-rv5j1201	1029	21	mediated	mediate	VBN
cord-022561-rv5j1201	1029	22	extravascular	extravascular	JJ
cord-022561-rv5j1201	1029	23	hemolysis	hemolysis	NN
cord-022561-rv5j1201	1029	24	.	.	.
cord-022561-rv5j1201	1030	1	The	the	DT
cord-022561-rv5j1201	1030	2	severity	severity	NN
cord-022561-rv5j1201	1030	3	of	of	IN
cord-022561-rv5j1201	1030	4	disease	disease	NN
cord-022561-rv5j1201	1030	5	in	in	IN
cord-022561-rv5j1201	1030	6	infected	infected	JJ
cord-022561-rv5j1201	1030	7	animals	animal	NNS
cord-022561-rv5j1201	1030	8	varies	vary	VBZ
cord-022561-rv5j1201	1030	9	with	with	IN
cord-022561-rv5j1201	1030	10	age	age	NN
cord-022561-rv5j1201	1030	11	.	.	.
cord-022561-rv5j1201	1031	1	Infected	infected	JJ
cord-022561-rv5j1201	1031	2	calves	calf	NNS
cord-022561-rv5j1201	1031	3	under	under	IN
cord-022561-rv5j1201	1031	4	1	1	CD
cord-022561-rv5j1201	1031	5	year	year	NN
cord-022561-rv5j1201	1031	6	of	of	IN
cord-022561-rv5j1201	1031	7	age	age	NN
cord-022561-rv5j1201	1031	8	rarely	rarely	RB
cord-022561-rv5j1201	1031	9	develop	develop	VBP
cord-022561-rv5j1201	1031	10	clinical	clinical	JJ
cord-022561-rv5j1201	1031	11	disease	disease	NN
cord-022561-rv5j1201	1031	12	,	,	,
cord-022561-rv5j1201	1031	13	whereas	whereas	IN
cord-022561-rv5j1201	1031	14	cattle	cattle	NNS
cord-022561-rv5j1201	1031	15	3	3	CD
cord-022561-rv5j1201	1031	16	years	year	NNS
cord-022561-rv5j1201	1031	17	of	of	IN
cord-022561-rv5j1201	1031	18	age	age	NN
cord-022561-rv5j1201	1031	19	or	or	CC
cord-022561-rv5j1201	1031	20	older	old	JJR
cord-022561-rv5j1201	1031	21	are	be	VBP
cord-022561-rv5j1201	1031	22	more	more	RBR
cord-022561-rv5j1201	1031	23	likely	likely	JJ
cord-022561-rv5j1201	1031	24	to	to	TO
cord-022561-rv5j1201	1031	25	develop	develop	VB
cord-022561-rv5j1201	1031	26	severe	severe	JJ
cord-022561-rv5j1201	1031	27	,	,	,
cord-022561-rv5j1201	1031	28	potentially	potentially	RB
cord-022561-rv5j1201	1031	29	fatal	fatal	JJ
cord-022561-rv5j1201	1031	30	,	,	,
cord-022561-rv5j1201	1031	31	illness	illness	NN
cord-022561-rv5j1201	1031	32	.	.	.
cord-022561-rv5j1201	1032	1	The	the	DT
cord-022561-rv5j1201	1032	2	reason	reason	NN
cord-022561-rv5j1201	1032	3	for	for	IN
cord-022561-rv5j1201	1032	4	this	this	DT
cord-022561-rv5j1201	1032	5	discrepancy	discrepancy	NN
cord-022561-rv5j1201	1032	6	is	be	VBZ
cord-022561-rv5j1201	1032	7	not	not	RB
cord-022561-rv5j1201	1032	8	clear	clear	JJ
cord-022561-rv5j1201	1032	9	.	.	.
cord-022561-rv5j1201	1033	1	Indian	indian	JJ
cord-022561-rv5j1201	1033	2	cattle	cattle	NNS
cord-022561-rv5j1201	1033	3	(	(	-LRB-
cord-022561-rv5j1201	1033	4	Bos	Bos	NNP
cord-022561-rv5j1201	1033	5	indicus	indicus	NN
cord-022561-rv5j1201	1033	6	)	)	-RRB-
cord-022561-rv5j1201	1033	7	are	be	VBP
cord-022561-rv5j1201	1033	8	more	more	RBR
cord-022561-rv5j1201	1033	9	resistant	resistant	JJ
cord-022561-rv5j1201	1033	10	to	to	IN
cord-022561-rv5j1201	1033	11	disease	disease	NN
cord-022561-rv5j1201	1033	12	than	than	IN
cord-022561-rv5j1201	1033	13	European	european	JJ
cord-022561-rv5j1201	1033	14	cattle	cattle	NNS
cord-022561-rv5j1201	1033	15	(	(	-LRB-
cord-022561-rv5j1201	1033	16	Bos	Bos	NNP
cord-022561-rv5j1201	1033	17	taurus	taurus	NNP
cord-022561-rv5j1201	1033	18	)	)	-RRB-
cord-022561-rv5j1201	1033	19	.	.	.
cord-022561-rv5j1201	1034	1	Surviving	survive	VBG
cord-022561-rv5j1201	1034	2	cattle	cattle	NNS
cord-022561-rv5j1201	1034	3	become	become	VBP
cord-022561-rv5j1201	1034	4	chronic	chronic	JJ
cord-022561-rv5j1201	1034	5	carriers	carrier	NNS
cord-022561-rv5j1201	1034	6	(	(	-LRB-
cord-022561-rv5j1201	1034	7	and	and	CC
cord-022561-rv5j1201	1034	8	thus	thus	RB
cord-022561-rv5j1201	1034	9	reservoirs	reservoir	NNS
cord-022561-rv5j1201	1034	10	for	for	IN
cord-022561-rv5j1201	1034	11	infection	infection	NN
cord-022561-rv5j1201	1034	12	of	of	IN
cord-022561-rv5j1201	1034	13	other	other	JJ
cord-022561-rv5j1201	1034	14	animals	animal	NNS
cord-022561-rv5j1201	1034	15	)	)	-RRB-
cord-022561-rv5j1201	1034	16	and	and	CC
cord-022561-rv5j1201	1034	17	develop	develop	VB
cord-022561-rv5j1201	1034	18	cyclic	cyclic	JJ
cord-022561-rv5j1201	1034	19	bacteremia	bacteremia	NN
cord-022561-rv5j1201	1034	20	,	,	,
cord-022561-rv5j1201	1034	21	which	which	WDT
cord-022561-rv5j1201	1034	22	is	be	VBZ
cord-022561-rv5j1201	1034	23	typically	typically	RB
cord-022561-rv5j1201	1034	24	not	not	RB
cord-022561-rv5j1201	1034	25	detectable	detectable	JJ
cord-022561-rv5j1201	1034	26	on	on	IN
cord-022561-rv5j1201	1034	27	blood	blood	NN
cord-022561-rv5j1201	1034	28	smears	smear	NNS
cord-022561-rv5j1201	1034	29	.	.	.
cord-022561-rv5j1201	1035	1	Splenectomy	Splenectomy	NNP
cord-022561-rv5j1201	1035	2	of	of	IN
cord-022561-rv5j1201	1035	3	carrier	carrier	NN
cord-022561-rv5j1201	1035	4	animals	animal	NNS
cord-022561-rv5j1201	1035	5	results	result	VBZ
cord-022561-rv5j1201	1035	6	in	in	IN
cord-022561-rv5j1201	1035	7	marked	marked	JJ
cord-022561-rv5j1201	1035	8	bacteremia	bacteremia	NN
cord-022561-rv5j1201	1035	9	and	and	CC
cord-022561-rv5j1201	1035	10	acute	acute	JJ
cord-022561-rv5j1201	1035	11	hemolysis	hemolysis	NN
cord-022561-rv5j1201	1035	12	.	.	.
cord-022561-rv5j1201	1036	1	PCR	PCR	NNP
cord-022561-rv5j1201	1036	2	testing	testing	NN
cord-022561-rv5j1201	1036	3	is	be	VBZ
cord-022561-rv5j1201	1036	4	the	the	DT
cord-022561-rv5j1201	1036	5	most	most	RBS
cord-022561-rv5j1201	1036	6	sensitive	sensitive	JJ
cord-022561-rv5j1201	1036	7	means	mean	NNS
cord-022561-rv5j1201	1036	8	of	of	IN
cord-022561-rv5j1201	1036	9	identifying	identify	VBG
cord-022561-rv5j1201	1036	10	animals	animal	NNS
cord-022561-rv5j1201	1036	11	with	with	IN
cord-022561-rv5j1201	1036	12	low	low	JJ
cord-022561-rv5j1201	1036	13	levels	level	NNS
cord-022561-rv5j1201	1036	14	of	of	IN
cord-022561-rv5j1201	1036	15	bacteremia	bacteremia	NN
cord-022561-rv5j1201	1036	16	.	.	.
cord-022561-rv5j1201	1037	1	Grossly	grossly	RB
cord-022561-rv5j1201	1037	2	,	,	,
cord-022561-rv5j1201	1037	3	acute	acute	JJ
cord-022561-rv5j1201	1037	4	disease	disease	NN
cord-022561-rv5j1201	1037	5	causes	cause	VBZ
cord-022561-rv5j1201	1037	6	lesions	lesion	NNS
cord-022561-rv5j1201	1037	7	of	of	IN
cord-022561-rv5j1201	1037	8	acute	acute	JJ
cord-022561-rv5j1201	1037	9	hemolytic	hemolytic	JJ
cord-022561-rv5j1201	1037	10	anemia	anemia	NN
cord-022561-rv5j1201	1037	11	,	,	,
cord-022561-rv5j1201	1037	12	including	include	VBG
cord-022561-rv5j1201	1037	13	pale	pale	JJ
cord-022561-rv5j1201	1037	14	mucous	mucous	JJ
cord-022561-rv5j1201	1037	15	membranes	membrane	NNS
cord-022561-rv5j1201	1037	16	,	,	,
cord-022561-rv5j1201	1037	17	low	low	JJ
cord-022561-rv5j1201	1037	18	blood	blood	NN
cord-022561-rv5j1201	1037	19	viscosity	viscosity	NN
cord-022561-rv5j1201	1037	20	,	,	,
cord-022561-rv5j1201	1037	21	icterus	icterus	NN
cord-022561-rv5j1201	1037	22	,	,	,
cord-022561-rv5j1201	1037	23	splenomegaly	splenomegaly	NN
cord-022561-rv5j1201	1037	24	,	,	,
cord-022561-rv5j1201	1037	25	hepatomegaly	hepatomegaly	NNP
cord-022561-rv5j1201	1037	26	,	,	,
cord-022561-rv5j1201	1037	27	and	and	CC
cord-022561-rv5j1201	1037	28	a	a	DT
cord-022561-rv5j1201	1037	29	distended	distended	JJ
cord-022561-rv5j1201	1037	30	gallbladder	gallbladder	NN
cord-022561-rv5j1201	1037	31	.	.	.
cord-022561-rv5j1201	1038	1	In	in	IN
cord-022561-rv5j1201	1038	2	animals	animal	NNS
cord-022561-rv5j1201	1038	3	with	with	IN
cord-022561-rv5j1201	1038	4	acute	acute	JJ
cord-022561-rv5j1201	1038	5	disease	disease	NN
cord-022561-rv5j1201	1038	6	it	-PRON-	PRP
cord-022561-rv5j1201	1038	7	is	be	VBZ
cord-022561-rv5j1201	1038	8	usually	usually	RB
cord-022561-rv5j1201	1038	9	easy	easy	JJ
cord-022561-rv5j1201	1038	10	to	to	TO
cord-022561-rv5j1201	1038	11	detect	detect	VB
cord-022561-rv5j1201	1038	12	A.	a.	NN
cord-022561-rv5j1201	1038	13	marginale	marginale	NN
cord-022561-rv5j1201	1038	14	organisms	organism	NNS
cord-022561-rv5j1201	1038	15	on	on	IN
cord-022561-rv5j1201	1038	16	routine	routine	JJ
cord-022561-rv5j1201	1038	17	blood	blood	NN
cord-022561-rv5j1201	1038	18	smear	smear	NN
cord-022561-rv5j1201	1038	19	evaluation	evaluation	NN
cord-022561-rv5j1201	1038	20	(	(	-LRB-
cord-022561-rv5j1201	1038	21	Fig	Fig	NNP
cord-022561-rv5j1201	1038	22	.	.	.
cord-022561-rv5j1201	1038	23	13	13	CD
cord-022561-rv5j1201	1038	24	-	-	SYM
cord-022561-rv5j1201	1038	25	26	26	CD
cord-022561-rv5j1201	1038	26	)	)	-RRB-
cord-022561-rv5j1201	1038	27	or	or	CC
cord-022561-rv5j1201	1038	28	impression	impression	NN
cord-022561-rv5j1201	1038	29	smears	smear	NNS
cord-022561-rv5j1201	1038	30	from	from	IN
cord-022561-rv5j1201	1038	31	cut	cut	NN
cord-022561-rv5j1201	1038	32	sections	section	NNS
cord-022561-rv5j1201	1038	33	of	of	IN
cord-022561-rv5j1201	1038	34	the	the	DT
cord-022561-rv5j1201	1038	35	spleen	spleen	NN
cord-022561-rv5j1201	1038	36	.	.	.
cord-022561-rv5j1201	1039	1	However	however	RB
cord-022561-rv5j1201	1039	2	,	,	,
cord-022561-rv5j1201	1039	3	in	in	IN
cord-022561-rv5j1201	1039	4	recovering	recover	VBG
cord-022561-rv5j1201	1039	5	animals	animal	NNS
cord-022561-rv5j1201	1039	6	,	,	,
cord-022561-rv5j1201	1039	7	the	the	DT
cord-022561-rv5j1201	1039	8	organisms	organism	NNS
cord-022561-rv5j1201	1039	9	may	may	MD
cord-022561-rv5j1201	1039	10	be	be	VB
cord-022561-rv5j1201	1039	11	difficult	difficult	JJ
cord-022561-rv5j1201	1039	12	to	to	TO
cord-022561-rv5j1201	1039	13	find	find	VB
cord-022561-rv5j1201	1039	14	.	.	.
cord-022561-rv5j1201	1040	1	Rickettsias	Rickettsias	NNP
cord-022561-rv5j1201	1040	2	that	that	WDT
cord-022561-rv5j1201	1040	3	infect	infect	VBP
cord-022561-rv5j1201	1040	4	leukocytes	leukocyte	NNS
cord-022561-rv5j1201	1040	5	are	be	VBP
cord-022561-rv5j1201	1040	6	broadly	broadly	RB
cord-022561-rv5j1201	1040	7	divided	divide	VBN
cord-022561-rv5j1201	1040	8	into	into	IN
cord-022561-rv5j1201	1040	9	those	those	DT
cord-022561-rv5j1201	1040	10	that	that	WDT
cord-022561-rv5j1201	1040	11	preferentially	preferentially	RB
cord-022561-rv5j1201	1040	12	infect	infect	VBP
cord-022561-rv5j1201	1040	13	granulocytes	granulocyte	NNS
cord-022561-rv5j1201	1040	14	(	(	-LRB-
cord-022561-rv5j1201	1040	15	In	in	IN
cord-022561-rv5j1201	1040	16	addition	addition	NN
cord-022561-rv5j1201	1040	17	to	to	IN
cord-022561-rv5j1201	1040	18	anemia	anemia	NN
cord-022561-rv5j1201	1040	19	,	,	,
cord-022561-rv5j1201	1040	20	common	common	JJ
cord-022561-rv5j1201	1040	21	findings	finding	NNS
cord-022561-rv5j1201	1040	22	in	in	IN
cord-022561-rv5j1201	1040	23	animals	animal	NNS
cord-022561-rv5j1201	1040	24	with	with	IN
cord-022561-rv5j1201	1040	25	leptospirosis	leptospirosis	NN
cord-022561-rv5j1201	1040	26	-	-	HYPH
cord-022561-rv5j1201	1040	27	induced	induce	VBN
cord-022561-rv5j1201	1040	28	hemolysis	hemolysis	NN
cord-022561-rv5j1201	1040	29	include	include	VBP
cord-022561-rv5j1201	1040	30	hemoglobinuria	hemoglobinuria	NNP
cord-022561-rv5j1201	1040	31	and	and	CC
cord-022561-rv5j1201	1040	32	icterus	icterus	NN
cord-022561-rv5j1201	1040	33	.	.	.
cord-022561-rv5j1201	1041	1	On	on	IN
cord-022561-rv5j1201	1041	2	necropsy	necropsy	JJ
cord-022561-rv5j1201	1041	3	,	,	,
cord-022561-rv5j1201	1041	4	renal	renal	JJ
cord-022561-rv5j1201	1041	5	tubular	tubular	JJ
cord-022561-rv5j1201	1041	6	necrosis	necrosis	NN
cord-022561-rv5j1201	1041	7	,	,	,
cord-022561-rv5j1201	1041	8	which	which	WDT
cord-022561-rv5j1201	1041	9	occurs	occur	VBZ
cord-022561-rv5j1201	1041	10	in	in	IN
cord-022561-rv5j1201	1041	11	part	part	NN
cord-022561-rv5j1201	1041	12	because	because	IN
cord-022561-rv5j1201	1041	13	of	of	IN
cord-022561-rv5j1201	1041	14	hemoglobinuria	hemoglobinuria	NNP
cord-022561-rv5j1201	1041	15	(	(	-LRB-
cord-022561-rv5j1201	1041	16	hemoglobinuric	hemoglobinuric	NNP
cord-022561-rv5j1201	1041	17	nephrosis	nephrosis	NNP
cord-022561-rv5j1201	1041	18	)	)	-RRB-
cord-022561-rv5j1201	1041	19	,	,	,
cord-022561-rv5j1201	1041	20	may	may	MD
cord-022561-rv5j1201	1041	21	also	also	RB
cord-022561-rv5j1201	1041	22	be	be	VB
cord-022561-rv5j1201	1041	23	present	present	JJ
cord-022561-rv5j1201	1041	24	.	.	.
cord-022561-rv5j1201	1042	1	Hemotropic	Hemotropic	NNP
cord-022561-rv5j1201	1042	2	Mycoplasmosis	Mycoplasmosis	NNP
cord-022561-rv5j1201	1042	3	(	(	-LRB-
cord-022561-rv5j1201	1042	4	Hemoplasmosis	Hemoplasmosis	NNP
cord-022561-rv5j1201	1042	5	)	)	-RRB-
cord-022561-rv5j1201	1042	6	.	.	.
cord-022561-rv5j1201	1043	1	The	the	DT
cord-022561-rv5j1201	1043	2	term	term	NN
cord-022561-rv5j1201	1043	3	hemotropic	hemotropic	NNP
cord-022561-rv5j1201	1043	4	mycoplasmas	mycoplasmas	NNP
cord-022561-rv5j1201	1043	5	,	,	,
cord-022561-rv5j1201	1043	6	or	or	CC
cord-022561-rv5j1201	1043	7	hemoplasmas	hemoplasmas	NNP
cord-022561-rv5j1201	1043	8	,	,	,
cord-022561-rv5j1201	1043	9	encompasses	encompass	VBZ
cord-022561-rv5j1201	1043	10	a	a	DT
cord-022561-rv5j1201	1043	11	group	group	NN
cord-022561-rv5j1201	1043	12	of	of	IN
cord-022561-rv5j1201	1043	13	bacteria	bacteria	NNS
cord-022561-rv5j1201	1043	14	,	,	,
cord-022561-rv5j1201	1043	15	formerly	formerly	RB
cord-022561-rv5j1201	1043	16	known	know	VBN
cord-022561-rv5j1201	1043	17	as	as	IN
cord-022561-rv5j1201	1043	18	Haemobartonella	Haemobartonella	NNP
cord-022561-rv5j1201	1043	19	or	or	CC
cord-022561-rv5j1201	1043	20	Eperythrozoon	Eperythrozoon	NNP
cord-022561-rv5j1201	1043	21	spp	spp	NNS
cord-022561-rv5j1201	1043	22	.	.	.
cord-022561-rv5j1201	1044	1	,	,	,
cord-022561-rv5j1201	1044	2	that	that	WDT
cord-022561-rv5j1201	1044	3	infect	infect	VBP
cord-022561-rv5j1201	1044	4	erythrocytes	erythrocyte	NNS
cord-022561-rv5j1201	1044	5	of	of	IN
cord-022561-rv5j1201	1044	6	many	many	JJ
cord-022561-rv5j1201	1044	7	domestic	domestic	JJ
cord-022561-rv5j1201	1044	8	,	,	,
cord-022561-rv5j1201	1044	9	laboratory	laboratory	NN
cord-022561-rv5j1201	1044	10	,	,	,
cord-022561-rv5j1201	1044	11	and	and	CC
cord-022561-rv5j1201	1044	12	wild	wild	JJ
cord-022561-rv5j1201	1044	13	animals	animal	NNS
cord-022561-rv5j1201	1044	14	.	.	.
cord-022561-rv5j1201	1045	1	Hemotropic	Hemotropic	NNP
cord-022561-rv5j1201	1045	2	mycoplasmas	mycoplasmas	IN
cord-022561-rv5j1201	1045	3	affecting	affect	VBG
cord-022561-rv5j1201	1045	4	common	common	JJ
cord-022561-rv5j1201	1045	5	domestic	domestic	JJ
cord-022561-rv5j1201	1045	6	species	specie	NNS
cord-022561-rv5j1201	1045	7	are	be	VBP
cord-022561-rv5j1201	1045	8	as	as	IN
cord-022561-rv5j1201	1045	9	follows	follow	VBZ
cord-022561-rv5j1201	1045	10	:	:	:
cord-022561-rv5j1201	1046	1	•	•	NNP
cord-022561-rv5j1201	1047	1	Cattle	Cattle	NNS
cord-022561-rv5j1201	1047	2	-	-	HYPH
cord-022561-rv5j1201	1047	3	Mycoplasma	Mycoplasma	NNP
cord-022561-rv5j1201	1047	4	wenyonii	wenyonii	NN
cord-022561-rv5j1201	1047	5	•	•	NNP
cord-022561-rv5j1201	1047	6	Camelids-"Candidatus	camelids-"candidatus	NN
cord-022561-rv5j1201	1047	7	Mycoplasma	Mycoplasma	NNP
cord-022561-rv5j1201	1047	8	haemolamae	haemolamae	NN
cord-022561-rv5j1201	1047	9	"	"	''
cord-022561-rv5j1201	1048	1	•	•	NNP
cord-022561-rv5j1201	1049	1	Sheep	Sheep	NNS
cord-022561-rv5j1201	1049	2	and	and	CC
cord-022561-rv5j1201	1049	3	goats	goat	NNS
cord-022561-rv5j1201	1049	4	-	-	HYPH
cord-022561-rv5j1201	1049	5	Mycoplasma	Mycoplasma	NNP
cord-022561-rv5j1201	1049	6	ovis	ovis	NN
cord-022561-rv5j1201	1049	7	•	•	NN
cord-022561-rv5j1201	1050	1	Pigs	pig	NNS
cord-022561-rv5j1201	1050	2	-	-	HYPH
cord-022561-rv5j1201	1050	3	Mycoplasma	Mycoplasma	NNP
cord-022561-rv5j1201	1050	4	suis	suis	NN
cord-022561-rv5j1201	1051	1	(	(	-LRB-
cord-022561-rv5j1201	1051	2	E-	E-	NNP
cord-022561-rv5j1201	1051	3	Fig	Fig	NNP
cord-022561-rv5j1201	1051	4	.	.	.
cord-022561-rv5j1201	1052	1	13	13	CD
cord-022561-rv5j1201	1052	2	-	-	SYM
cord-022561-rv5j1201	1052	3	4	4	CD
cord-022561-rv5j1201	1052	4	)	)	-RRB-
cord-022561-rv5j1201	1053	1	•	•	NNP
cord-022561-rv5j1201	1054	1	Dogs	dog	NNS
cord-022561-rv5j1201	1054	2	-	-	HYPH
cord-022561-rv5j1201	1054	3	Mycoplasma	mycoplasma	NN
cord-022561-rv5j1201	1054	4	haemocanis	haemocanis	NN
cord-022561-rv5j1201	1054	5	,	,	,
cord-022561-rv5j1201	1054	6	"	"	''
cord-022561-rv5j1201	1054	7	Candidatus	Candidatus	NNP
cord-022561-rv5j1201	1054	8	Mycoplasma	Mycoplasma	NNP
cord-022561-rv5j1201	1054	9	haematoparvum	haematoparvum	NN
cord-022561-rv5j1201	1054	10	"	"	''
cord-022561-rv5j1201	1055	1	•	•	NNP
cord-022561-rv5j1201	1056	1	Cats	cat	NNS
cord-022561-rv5j1201	1056	2	-	-	HYPH
cord-022561-rv5j1201	1056	3	Mycoplasma	mycoplasma	NN
cord-022561-rv5j1201	1056	4	haemofelis	haemofeli	VBD
cord-022561-rv5j1201	1056	5	,	,	,
cord-022561-rv5j1201	1056	6	"	"	''
cord-022561-rv5j1201	1056	7	Candidatus	Candidatus	NNP
cord-022561-rv5j1201	1056	8	Mycoplasma	Mycoplasma	NNP
cord-022561-rv5j1201	1056	9	haemominutum	haemominutum	RB
cord-022561-rv5j1201	1056	10	,	,	,
cord-022561-rv5j1201	1056	11	"	"	''
cord-022561-rv5j1201	1056	12	"	"	``
cord-022561-rv5j1201	1056	13	Candidatus	Candidatus	NNP
cord-022561-rv5j1201	1056	14	Mycoplasma	Mycoplasma	NNP
cord-022561-rv5j1201	1056	15	turicensus	turicensus	XX
cord-022561-rv5j1201	1056	16	"	"	''
cord-022561-rv5j1201	1057	1	Like	like	IN
cord-022561-rv5j1201	1057	2	other	other	JJ
cord-022561-rv5j1201	1057	3	mycoplasmas	mycoplasmas	NN
cord-022561-rv5j1201	1057	4	,	,	,
cord-022561-rv5j1201	1057	5	hemoplasmas	hemoplasmas	NNP
cord-022561-rv5j1201	1057	6	are	be	VBP
cord-022561-rv5j1201	1057	7	small	small	JJ
cord-022561-rv5j1201	1057	8	(	(	-LRB-
cord-022561-rv5j1201	1057	9	0.3	0.3	CD
cord-022561-rv5j1201	1057	10	to	to	TO
cord-022561-rv5j1201	1057	11	3	3	CD
cord-022561-rv5j1201	1057	12	µm	µm	NN
cord-022561-rv5j1201	1057	13	in	in	IN
cord-022561-rv5j1201	1057	14	diameter	diameter	NN
cord-022561-rv5j1201	1057	15	)	)	-RRB-
cord-022561-rv5j1201	1057	16	and	and	CC
cord-022561-rv5j1201	1057	17	lack	lack	VBP
cord-022561-rv5j1201	1057	18	a	a	DT
cord-022561-rv5j1201	1057	19	cell	cell	NN
cord-022561-rv5j1201	1057	20	wall	wall	NN
cord-022561-rv5j1201	1057	21	.	.	.
cord-022561-rv5j1201	1058	1	They	-PRON-	PRP
cord-022561-rv5j1201	1058	2	are	be	VBP
cord-022561-rv5j1201	1058	3	epicellular	epicellular	NNS
cord-022561-rv5j1201	1058	4	parasites	parasite	NNS
cord-022561-rv5j1201	1058	5	,	,	,
cord-022561-rv5j1201	1058	6	residing	reside	VBG
cord-022561-rv5j1201	1058	7	in	in	IN
cord-022561-rv5j1201	1058	8	indentations	indentation	NNS
cord-022561-rv5j1201	1058	9	and	and	CC
cord-022561-rv5j1201	1058	10	invaginations	invagination	NNS
cord-022561-rv5j1201	1058	11	of	of	IN
cord-022561-rv5j1201	1058	12	red	red	JJ
cord-022561-rv5j1201	1058	13	blood	blood	NN
cord-022561-rv5j1201	1058	14	cell	cell	NN
cord-022561-rv5j1201	1058	15	surfaces	surface	NNS
cord-022561-rv5j1201	1058	16	.	.	.
cord-022561-rv5j1201	1059	1	The	the	DT
cord-022561-rv5j1201	1059	2	mode	mode	NN
cord-022561-rv5j1201	1059	3	of	of	IN
cord-022561-rv5j1201	1059	4	transmission	transmission	NN
cord-022561-rv5j1201	1059	5	is	be	VBZ
cord-022561-rv5j1201	1059	6	poorly	poorly	RB
cord-022561-rv5j1201	1059	7	understood	understand	VBN
cord-022561-rv5j1201	1059	8	,	,	,
cord-022561-rv5j1201	1059	9	but	but	CC
cord-022561-rv5j1201	1059	10	blood	blood	NN
cord-022561-rv5j1201	1059	11	-	-	HYPH
cord-022561-rv5j1201	1059	12	sucking	suck	VBG
cord-022561-rv5j1201	1059	13	arthropods	arthropod	NNS
cord-022561-rv5j1201	1059	14	are	be	VBP
cord-022561-rv5j1201	1059	15	believed	believe	VBN
cord-022561-rv5j1201	1059	16	to	to	TO
cord-022561-rv5j1201	1059	17	play	play	VB
cord-022561-rv5j1201	1059	18	a	a	DT
cord-022561-rv5j1201	1059	19	role	role	NN
cord-022561-rv5j1201	1059	20	;	;	:
cord-022561-rv5j1201	1059	21	transmission	transmission	NN
cord-022561-rv5j1201	1059	22	in	in	IN
cord-022561-rv5j1201	1059	23	utero	utero	NN
cord-022561-rv5j1201	1059	24	,	,	,
cord-022561-rv5j1201	1059	25	through	through	IN
cord-022561-rv5j1201	1059	26	biting	bite	VBG
cord-022561-rv5j1201	1059	27	or	or	CC
cord-022561-rv5j1201	1059	28	fighting	fighting	NN
cord-022561-rv5j1201	1059	29	,	,	,
cord-022561-rv5j1201	1059	30	and	and	CC
cord-022561-rv5j1201	1059	31	transfusion	transfusion	NN
cord-022561-rv5j1201	1059	32	of	of	IN
cord-022561-rv5j1201	1059	33	infected	infected	JJ
cord-022561-rv5j1201	1059	34	blood	blood	NN
cord-022561-rv5j1201	1059	35	products	product	NNS
cord-022561-rv5j1201	1059	36	are	be	VBP
cord-022561-rv5j1201	1059	37	also	also	RB
cord-022561-rv5j1201	1059	38	suspected	suspect	VBN
cord-022561-rv5j1201	1059	39	.	.	.
cord-022561-rv5j1201	1060	1	Effects	effect	NNS
cord-022561-rv5j1201	1060	2	of	of	IN
cord-022561-rv5j1201	1060	3	infection	infection	NN
cord-022561-rv5j1201	1060	4	vary	vary	VBP
cord-022561-rv5j1201	1060	5	from	from	IN
cord-022561-rv5j1201	1060	6	subclinical	subclinical	JJ
cord-022561-rv5j1201	1060	7	to	to	IN
cord-022561-rv5j1201	1060	8	fatal	fatal	JJ
cord-022561-rv5j1201	1060	9	anemia	anemia	NN
cord-022561-rv5j1201	1060	10	,	,	,
cord-022561-rv5j1201	1060	11	depending	depend	VBG
cord-022561-rv5j1201	1060	12	on	on	IN
cord-022561-rv5j1201	1060	13	the	the	DT
cord-022561-rv5j1201	1060	14	specific	specific	JJ
cord-022561-rv5j1201	1060	15	organism	organism	NN
cord-022561-rv5j1201	1060	16	,	,	,
cord-022561-rv5j1201	1060	17	dose	dose	NN
cord-022561-rv5j1201	1060	18	,	,	,
cord-022561-rv5j1201	1060	19	and	and	CC
cord-022561-rv5j1201	1060	20	host	host	NN
cord-022561-rv5j1201	1060	21	susceptibility	susceptibility	NN
cord-022561-rv5j1201	1060	22	.	.	.
cord-022561-rv5j1201	1061	1	Most	Most	JJS
cord-022561-rv5j1201	1061	2	hemoplasmas	hemoplasma	NNS
cord-022561-rv5j1201	1061	3	are	be	VBP
cord-022561-rv5j1201	1061	4	more	more	RBR
cord-022561-rv5j1201	1061	5	likely	likely	JJ
cord-022561-rv5j1201	1061	6	to	to	TO
cord-022561-rv5j1201	1061	7	cause	cause	VB
cord-022561-rv5j1201	1061	8	acute	acute	JJ
cord-022561-rv5j1201	1061	9	illness	illness	NN
cord-022561-rv5j1201	1061	10	in	in	IN
cord-022561-rv5j1201	1061	11	individuals	individual	NNS
cord-022561-rv5j1201	1061	12	that	that	WDT
cord-022561-rv5j1201	1061	13	are	be	VBP
cord-022561-rv5j1201	1061	14	immunocompromised	immunocompromised	JJ
cord-022561-rv5j1201	1061	15	or	or	CC
cord-022561-rv5j1201	1061	16	have	have	VBP
cord-022561-rv5j1201	1061	17	concurrent	concurrent	JJ
cord-022561-rv5j1201	1061	18	disease	disease	NN
cord-022561-rv5j1201	1061	19	.	.	.
cord-022561-rv5j1201	1062	1	However	however	RB
cord-022561-rv5j1201	1062	2	,	,	,
cord-022561-rv5j1201	1062	3	M.	M.	NNP
cord-022561-rv5j1201	1062	4	haemofelis	haemofelis	NNP
cord-022561-rv5j1201	1062	5	is	be	VBZ
cord-022561-rv5j1201	1062	6	an	an	DT
cord-022561-rv5j1201	1062	7	exception	exception	NN
cord-022561-rv5j1201	1062	8	and	and	CC
cord-022561-rv5j1201	1062	9	tends	tend	VBZ
cord-022561-rv5j1201	1062	10	to	to	TO
cord-022561-rv5j1201	1062	11	cause	cause	VB
cord-022561-rv5j1201	1062	12	acute	acute	JJ
cord-022561-rv5j1201	1062	13	hemolytic	hemolytic	JJ
cord-022561-rv5j1201	1062	14	anemia	anemia	NN
cord-022561-rv5j1201	1062	15	in	in	IN
cord-022561-rv5j1201	1062	16	immunocompetent	immunocompetent	JJ
cord-022561-rv5j1201	1062	17	cats	cat	NNS
cord-022561-rv5j1201	1062	18	.	.	.
cord-022561-rv5j1201	1063	1	Anemia	anemia	NN
cord-022561-rv5j1201	1063	2	occurs	occur	VBZ
cord-022561-rv5j1201	1063	3	mainly	mainly	RB
cord-022561-rv5j1201	1063	4	because	because	IN
cord-022561-rv5j1201	1063	5	of	of	IN
cord-022561-rv5j1201	1063	6	extravascular	extravascular	JJ
cord-022561-rv5j1201	1063	7	hemolysis	hemolysis	NN
cord-022561-rv5j1201	1063	8	,	,	,
cord-022561-rv5j1201	1063	9	but	but	CC
cord-022561-rv5j1201	1063	10	intravascular	intravascular	JJ
cord-022561-rv5j1201	1063	11	hemolysis	hemolysis	NN
cord-022561-rv5j1201	1063	12	also	also	RB
cord-022561-rv5j1201	1063	13	occurs	occur	VBZ
cord-022561-rv5j1201	1063	14	.	.	.
cord-022561-rv5j1201	1064	1	Although	although	IN
cord-022561-rv5j1201	1064	2	the	the	DT
cord-022561-rv5j1201	1064	3	pathogenic	pathogenic	JJ
cord-022561-rv5j1201	1064	4	mechanisms	mechanism	NNS
cord-022561-rv5j1201	1064	5	are	be	VBP
cord-022561-rv5j1201	1064	6	not	not	RB
cord-022561-rv5j1201	1064	7	completely	completely	RB
cord-022561-rv5j1201	1064	8	understood	understand	VBN
cord-022561-rv5j1201	1064	9	,	,	,
cord-022561-rv5j1201	1064	10	an	an	DT
cord-022561-rv5j1201	1064	11	immune	immune	NN
cord-022561-rv5j1201	1064	12	-	-	HYPH
cord-022561-rv5j1201	1064	13	mediated	mediate	VBN
cord-022561-rv5j1201	1064	14	component	component	NN
cord-022561-rv5j1201	1064	15	is	be	VBZ
cord-022561-rv5j1201	1064	16	highly	highly	RB
cord-022561-rv5j1201	1064	17	probable	probable	JJ
cord-022561-rv5j1201	1064	18	,	,	,
cord-022561-rv5j1201	1064	19	as	as	RB
cord-022561-rv5j1201	1064	20	well	well	RB
cord-022561-rv5j1201	1064	21	as	as	IN
cord-022561-rv5j1201	1064	22	direct	direct	JJ
cord-022561-rv5j1201	1064	23	red	red	JJ
cord-022561-rv5j1201	1064	24	blood	blood	NN
cord-022561-rv5j1201	1064	25	cell	cell	NN
cord-022561-rv5j1201	1064	26	injury	injury	NN
cord-022561-rv5j1201	1064	27	by	by	IN
cord-022561-rv5j1201	1064	28	the	the	DT
cord-022561-rv5j1201	1064	29	bacteria	bacteria	NNS
cord-022561-rv5j1201	1064	30	and	and	CC
cord-022561-rv5j1201	1064	31	the	the	DT
cord-022561-rv5j1201	1064	32	innocent	innocent	JJ
cord-022561-rv5j1201	1064	33	bystander	bystander	NN
cord-022561-rv5j1201	1064	34	effect	effect	NN
cord-022561-rv5j1201	1064	35	.	.	.
cord-022561-rv5j1201	1065	1	Hemotropic	Hemotropic	NNP
cord-022561-rv5j1201	1065	2	mycoplasmas	mycoplasma	NNS
cord-022561-rv5j1201	1065	3	induce	induce	VBP
cord-022561-rv5j1201	1065	4	cold	cold	JJ
cord-022561-rv5j1201	1065	5	agglutinins	agglutinin	NNS
cord-022561-rv5j1201	1065	6	in	in	IN
cord-022561-rv5j1201	1065	7	infected	infected	JJ
cord-022561-rv5j1201	1065	8	individuals	individual	NNS
cord-022561-rv5j1201	1065	9	,	,	,
cord-022561-rv5j1201	1065	10	although	although	IN
cord-022561-rv5j1201	1065	11	it	-PRON-	PRP
cord-022561-rv5j1201	1065	12	is	be	VBZ
cord-022561-rv5j1201	1065	13	not	not	RB
cord-022561-rv5j1201	1065	14	clear	clear	JJ
cord-022561-rv5j1201	1065	15	whether	whether	IN
cord-022561-rv5j1201	1065	16	these	these	DT
cord-022561-rv5j1201	1065	17	particular	particular	JJ
cord-022561-rv5j1201	1065	18	antibodies	antibody	NNS
cord-022561-rv5j1201	1065	19	are	be	VBP
cord-022561-rv5j1201	1065	20	important	important	JJ
cord-022561-rv5j1201	1065	21	in	in	IN
cord-022561-rv5j1201	1065	22	the	the	DT
cord-022561-rv5j1201	1065	23	development	development	NN
cord-022561-rv5j1201	1065	24	of	of	IN
cord-022561-rv5j1201	1065	25	hemolytic	hemolytic	JJ
cord-022561-rv5j1201	1065	26	anemia	anemia	NN
cord-022561-rv5j1201	1065	27	.	.	.
cord-022561-rv5j1201	1066	1	When	when	WRB
cord-022561-rv5j1201	1066	2	detected	detect	VBN
cord-022561-rv5j1201	1066	3	on	on	IN
cord-022561-rv5j1201	1066	4	routine	routine	JJ
cord-022561-rv5j1201	1066	5	blood	blood	NN
cord-022561-rv5j1201	1066	6	smear	smear	NN
cord-022561-rv5j1201	1066	7	evaluation	evaluation	NN
cord-022561-rv5j1201	1066	8	,	,	,
cord-022561-rv5j1201	1066	9	the	the	DT
cord-022561-rv5j1201	1066	10	organisms	organism	NNS
cord-022561-rv5j1201	1066	11	are	be	VBP
cord-022561-rv5j1201	1066	12	variably	variably	RB
cord-022561-rv5j1201	1066	13	shaped	shape	VBN
cord-022561-rv5j1201	1066	14	(	(	-LRB-
cord-022561-rv5j1201	1066	15	cocci	coccus	NNS
cord-022561-rv5j1201	1066	16	,	,	,
cord-022561-rv5j1201	1066	17	small	small	JJ
cord-022561-rv5j1201	1066	18	rods	rod	NNS
cord-022561-rv5j1201	1066	19	,	,	,
cord-022561-rv5j1201	1066	20	or	or	CC
cord-022561-rv5j1201	1066	21	ring	ring	NN
cord-022561-rv5j1201	1066	22	forms	form	NNS
cord-022561-rv5j1201	1066	23	)	)	-RRB-
cord-022561-rv5j1201	1066	24	and	and	CC
cord-022561-rv5j1201	1066	25	sometimes	sometimes	RB
cord-022561-rv5j1201	1066	26	arranged	arrange	VBN
cord-022561-rv5j1201	1066	27	in	in	IN
cord-022561-rv5j1201	1066	28	short	short	JJ
cord-022561-rv5j1201	1066	29	,	,	,
cord-022561-rv5j1201	1066	30	branching	branch	VBG
cord-022561-rv5j1201	1066	31	chains	chain	NNS
cord-022561-rv5j1201	1066	32	(	(	-LRB-
cord-022561-rv5j1201	1066	33	Fig	Fig	NNP
cord-022561-rv5j1201	1066	34	.	.	.
cord-022561-rv5j1201	1066	35	13	13	CD
cord-022561-rv5j1201	1066	36	-	-	SYM
cord-022561-rv5j1201	1066	37	28	28	CD
cord-022561-rv5j1201	1066	38	)	)	-RRB-
cord-022561-rv5j1201	1066	39	.	.	.
cord-022561-rv5j1201	1067	1	The	the	DT
cord-022561-rv5j1201	1067	2	organisms	organism	NNS
cord-022561-rv5j1201	1067	3	may	may	MD
cord-022561-rv5j1201	1067	4	also	also	RB
cord-022561-rv5j1201	1067	5	be	be	VB
cord-022561-rv5j1201	1067	6	noted	note	VBN
cord-022561-rv5j1201	1067	7	extracellularly	extracellularly	RB
cord-022561-rv5j1201	1067	8	,	,	,
cord-022561-rv5j1201	1067	9	in	in	IN
cord-022561-rv5j1201	1067	10	the	the	DT
cord-022561-rv5j1201	1067	11	background	background	NN
cord-022561-rv5j1201	1067	12	of	of	IN
cord-022561-rv5j1201	1067	13	the	the	DT
cord-022561-rv5j1201	1067	14	blood	blood	NN
cord-022561-rv5j1201	1067	15	smear	smear	NN
cord-022561-rv5j1201	1067	16	,	,	,
cord-022561-rv5j1201	1067	17	especially	especially	RB
cord-022561-rv5j1201	1067	18	if	if	IN
cord-022561-rv5j1201	1067	19	the	the	DT
cord-022561-rv5j1201	1067	20	smear	smear	NN
cord-022561-rv5j1201	1067	21	is	be	VBZ
cord-022561-rv5j1201	1067	22	made	make	VBN
cord-022561-rv5j1201	1067	23	after	after	IN
cord-022561-rv5j1201	1067	24	prolonged	prolong	VBN
cord-022561-rv5j1201	1067	25	storage	storage	NN
cord-022561-rv5j1201	1067	26	of	of	IN
cord-022561-rv5j1201	1067	27	the	the	DT
cord-022561-rv5j1201	1067	28	blood	blood	NN
cord-022561-rv5j1201	1067	29	in	in	IN
cord-022561-rv5j1201	1067	30	an	an	DT
cord-022561-rv5j1201	1067	31	anticoagulant	anticoagulant	JJ
cord-022561-rv5j1201	1067	32	tube	tube	NN
cord-022561-rv5j1201	1067	33	.	.	.
cord-022561-rv5j1201	1068	1	In	in	IN
cord-022561-rv5j1201	1068	2	animals	animal	NNS
cord-022561-rv5j1201	1068	3	dying	die	VBG
cord-022561-rv5j1201	1068	4	of	of	IN
cord-022561-rv5j1201	1068	5	acute	acute	JJ
cord-022561-rv5j1201	1068	6	hemoplasma	hemoplasma	JJ
cord-022561-rv5j1201	1068	7	infection	infection	NN
cord-022561-rv5j1201	1068	8	,	,	,
cord-022561-rv5j1201	1068	9	the	the	DT
cord-022561-rv5j1201	1068	10	gross	gross	JJ
cord-022561-rv5j1201	1068	11	findings	finding	NNS
cord-022561-rv5j1201	1068	12	are	be	VBP
cord-022561-rv5j1201	1068	13	typical	typical	JJ
cord-022561-rv5j1201	1068	14	of	of	IN
cord-022561-rv5j1201	1068	15	extravascular	extravascular	JJ
cord-022561-rv5j1201	1068	16	hemolysis	hemolysis	NN
cord-022561-rv5j1201	1068	17	,	,	,
cord-022561-rv5j1201	1068	18	with	with	IN
cord-022561-rv5j1201	1068	19	pallor	pallor	NN
cord-022561-rv5j1201	1068	20	,	,	,
cord-022561-rv5j1201	1068	21	icterus	icterus	NN
cord-022561-rv5j1201	1068	22	,	,	,
cord-022561-rv5j1201	1068	23	splenomegaly	splenomegaly	NN
cord-022561-rv5j1201	1068	24	,	,	,
cord-022561-rv5j1201	1068	25	and	and	CC
cord-022561-rv5j1201	1068	26	distended	distended	JJ
cord-022561-rv5j1201	1068	27	gallbladder	gallbladder	NN
cord-022561-rv5j1201	1068	28	(	(	-LRB-
cord-022561-rv5j1201	1068	29	Fig	Fig	NNP
cord-022561-rv5j1201	1068	30	.	.	.
cord-022561-rv5j1201	1068	31	13	13	CD
cord-022561-rv5j1201	1068	32	-	-	SYM
cord-022561-rv5j1201	1068	33	29	29	CD
cord-022561-rv5j1201	1068	34	)	)	-RRB-
cord-022561-rv5j1201	1068	35	.	.	.
cord-022561-rv5j1201	1069	1	Additional	additional	JJ
cord-022561-rv5j1201	1069	2	lesions	lesion	NNS
cord-022561-rv5j1201	1069	3	documented	document	VBN
cord-022561-rv5j1201	1069	4	in	in	IN
cord-022561-rv5j1201	1069	5	cattle	cattle	NNS
cord-022561-rv5j1201	1069	6	include	include	VBP
cord-022561-rv5j1201	1069	7	scrotal	scrotal	JJ
cord-022561-rv5j1201	1069	8	and	and	CC
cord-022561-rv5j1201	1069	9	hind	hind	JJ
cord-022561-rv5j1201	1069	10	limb	limb	NN
cord-022561-rv5j1201	1069	11	edema	edema	NN
cord-022561-rv5j1201	1069	12	and	and	CC
cord-022561-rv5j1201	1069	13	swelling	swelling	NN
cord-022561-rv5j1201	1069	14	of	of	IN
cord-022561-rv5j1201	1069	15	the	the	DT
cord-022561-rv5j1201	1069	16	teats	teat	NNS
cord-022561-rv5j1201	1069	17	.	.	.
cord-022561-rv5j1201	1070	1	Microscopic	microscopic	JJ
cord-022561-rv5j1201	1070	2	lesions	lesion	NNS
cord-022561-rv5j1201	1070	3	in	in	IN
cord-022561-rv5j1201	1070	4	the	the	DT
cord-022561-rv5j1201	1070	5	red	red	JJ
cord-022561-rv5j1201	1070	6	pulp	pulp	NN
cord-022561-rv5j1201	1070	7	of	of	IN
cord-022561-rv5j1201	1070	8	the	the	DT
cord-022561-rv5j1201	1070	9	spleen	spleen	NNS
cord-022561-rv5j1201	1070	10	include	include	VBP
cord-022561-rv5j1201	1070	11	congestion	congestion	NN
cord-022561-rv5j1201	1070	12	,	,	,
cord-022561-rv5j1201	1070	13	erythrophagocytosis	erythrophagocytosis	NNP
cord-022561-rv5j1201	1070	14	,	,	,
cord-022561-rv5j1201	1070	15	macrophage	macrophage	NN
cord-022561-rv5j1201	1070	16	hyperplasia	hyperplasia	NN
cord-022561-rv5j1201	1070	17	,	,	,
cord-022561-rv5j1201	1070	18	EMH	EMH	NNP
cord-022561-rv5j1201	1070	19	,	,	,
cord-022561-rv5j1201	1070	20	and	and	CC
cord-022561-rv5j1201	1070	21	increased	increase	VBN
cord-022561-rv5j1201	1070	22	numbers	number	NNS
cord-022561-rv5j1201	1070	23	of	of	IN
cord-022561-rv5j1201	1070	24	plasma	plasma	NN
cord-022561-rv5j1201	1070	25	cells	cell	NNS
cord-022561-rv5j1201	1070	26	.	.	.
cord-022561-rv5j1201	1071	1	Bone	bone	NN
cord-022561-rv5j1201	1071	2	marrow	marrow	NN
cord-022561-rv5j1201	1071	3	has	have	VBZ
cord-022561-rv5j1201	1071	4	varying	vary	VBG
cord-022561-rv5j1201	1071	5	degrees	degree	NNS
cord-022561-rv5j1201	1071	6	of	of	IN
cord-022561-rv5j1201	1071	7	erythroid	erythroid	JJ
cord-022561-rv5j1201	1071	8	hyperplasia	hyperplasia	NN
cord-022561-rv5j1201	1071	9	,	,	,
cord-022561-rv5j1201	1071	10	depending	depend	VBG
cord-022561-rv5j1201	1071	11	on	on	IN
cord-022561-rv5j1201	1071	12	the	the	DT
cord-022561-rv5j1201	1071	13	duration	duration	NN
cord-022561-rv5j1201	1071	14	of	of	IN
cord-022561-rv5j1201	1071	15	hemolysis	hemolysis	NN
cord-022561-rv5j1201	1071	16	.	.	.
cord-022561-rv5j1201	1072	1	Immune	immune	NN
cord-022561-rv5j1201	1072	2	-	-	HYPH
cord-022561-rv5j1201	1072	3	Mediated	mediate	VBN
cord-022561-rv5j1201	1072	4	Hemolytic	hemolytic	JJ
cord-022561-rv5j1201	1072	5	Anemia	anemia	NN
cord-022561-rv5j1201	1072	6	.	.	.
cord-022561-rv5j1201	1073	1	Immune	immune	NN
cord-022561-rv5j1201	1073	2	-	-	HYPH
cord-022561-rv5j1201	1073	3	mediated	mediate	VBN
cord-022561-rv5j1201	1073	4	hemolytic	hemolytic	JJ
cord-022561-rv5j1201	1073	5	anemia	anemia	NN
cord-022561-rv5j1201	1073	6	is	be	VBZ
cord-022561-rv5j1201	1073	7	a	a	DT
cord-022561-rv5j1201	1073	8	condition	condition	NN
cord-022561-rv5j1201	1073	9	characterized	characterize	VBN
cord-022561-rv5j1201	1073	10	by	by	IN
cord-022561-rv5j1201	1073	11	increased	increase	VBN
cord-022561-rv5j1201	1073	12	destruction	destruction	NN
cord-022561-rv5j1201	1073	13	of	of	IN
cord-022561-rv5j1201	1073	14	erythrocytes	erythrocyte	NNS
cord-022561-rv5j1201	1073	15	because	because	IN
cord-022561-rv5j1201	1073	16	of	of	IN
cord-022561-rv5j1201	1073	17	binding	binding	NN
cord-022561-rv5j1201	1073	18	of	of	IN
cord-022561-rv5j1201	1073	19	immunoglobulin	immunoglobulin	NN
cord-022561-rv5j1201	1073	20	to	to	IN
cord-022561-rv5j1201	1073	21	red	red	JJ
cord-022561-rv5j1201	1073	22	blood	blood	NN
cord-022561-rv5j1201	1073	23	cell	cell	NN
cord-022561-rv5j1201	1073	24	surface	surface	NN
cord-022561-rv5j1201	1073	25	antigens	antigen	NNS
cord-022561-rv5j1201	1073	26	.	.	.
cord-022561-rv5j1201	1074	1	It	-PRON-	PRP
cord-022561-rv5j1201	1074	2	is	be	VBZ
cord-022561-rv5j1201	1074	3	a	a	DT
cord-022561-rv5j1201	1074	4	common	common	JJ
cord-022561-rv5j1201	1074	5	,	,	,
cord-022561-rv5j1201	1074	6	life	life	NN
cord-022561-rv5j1201	1074	7	-	-	HYPH
cord-022561-rv5j1201	1074	8	threatening	threaten	VBG
cord-022561-rv5j1201	1074	9	condition	condition	NN
cord-022561-rv5j1201	1074	10	in	in	IN
cord-022561-rv5j1201	1074	11	dogs	dog	NNS
cord-022561-rv5j1201	1074	12	but	but	CC
cord-022561-rv5j1201	1074	13	also	also	RB
cord-022561-rv5j1201	1074	14	has	have	VBZ
cord-022561-rv5j1201	1074	15	been	be	VBN
cord-022561-rv5j1201	1074	16	described	describe	VBN
cord-022561-rv5j1201	1074	17	in	in	IN
cord-022561-rv5j1201	1074	18	horses	horse	NNS
cord-022561-rv5j1201	1074	19	,	,	,
cord-022561-rv5j1201	1074	20	cattle	cattle	NNS
cord-022561-rv5j1201	1074	21	,	,	,
cord-022561-rv5j1201	1074	22	and	and	CC
cord-022561-rv5j1201	1074	23	cats	cat	NNS
cord-022561-rv5j1201	1074	24	.	.	.
cord-022561-rv5j1201	1075	1	Immune	immune	NN
cord-022561-rv5j1201	1075	2	-	-	HYPH
cord-022561-rv5j1201	1075	3	mediated	mediate	VBN
cord-022561-rv5j1201	1075	4	hemolytic	hemolytic	JJ
cord-022561-rv5j1201	1075	5	anemia	anemia	NN
cord-022561-rv5j1201	1075	6	may	may	MD
cord-022561-rv5j1201	1075	7	be	be	VB
cord-022561-rv5j1201	1075	8	idiopathic	idiopathic	JJ
cord-022561-rv5j1201	1075	9	(	(	-LRB-
cord-022561-rv5j1201	1075	10	also	also	RB
cord-022561-rv5j1201	1075	11	called	call	VBN
cord-022561-rv5j1201	1075	12	edema	edema	NN
cord-022561-rv5j1201	1075	13	,	,	,
cord-022561-rv5j1201	1075	14	cavitary	cavitary	JJ
cord-022561-rv5j1201	1075	15	effusions	effusion	NNS
cord-022561-rv5j1201	1075	16	,	,	,
cord-022561-rv5j1201	1075	17	and	and	CC
cord-022561-rv5j1201	1075	18	effusive	effusive	JJ
cord-022561-rv5j1201	1075	19	polyarthropathy	polyarthropathy	NN
cord-022561-rv5j1201	1075	20	.	.	.
cord-022561-rv5j1201	1076	1	Hydropericardium	Hydropericardium	NNP
cord-022561-rv5j1201	1076	2	gives	give	VBZ
cord-022561-rv5j1201	1076	3	heartwater	heartwater	NNP
cord-022561-rv5j1201	1076	4	its	-PRON-	PRP$
cord-022561-rv5j1201	1076	5	name	name	NN
cord-022561-rv5j1201	1076	6	but	but	CC
cord-022561-rv5j1201	1076	7	is	be	VBZ
cord-022561-rv5j1201	1076	8	more	more	RBR
cord-022561-rv5j1201	1076	9	consistently	consistently	RB
cord-022561-rv5j1201	1076	10	found	find	VBN
cord-022561-rv5j1201	1076	11	in	in	IN
cord-022561-rv5j1201	1076	12	small	small	JJ
cord-022561-rv5j1201	1076	13	ruminants	ruminant	NNS
cord-022561-rv5j1201	1076	14	than	than	IN
cord-022561-rv5j1201	1076	15	in	in	IN
cord-022561-rv5j1201	1076	16	cattle	cattle	NNS
cord-022561-rv5j1201	1076	17	.	.	.
cord-022561-rv5j1201	1077	1	Chronically	chronically	RB
cord-022561-rv5j1201	1077	2	infected	infected	JJ
cord-022561-rv5j1201	1077	3	dogs	dog	NNS
cord-022561-rv5j1201	1077	4	are	be	VBP
cord-022561-rv5j1201	1077	5	emaciated	emaciated	JJ
cord-022561-rv5j1201	1077	6	.	.	.
cord-022561-rv5j1201	1078	1	The	the	DT
cord-022561-rv5j1201	1078	2	bone	bone	NN
cord-022561-rv5j1201	1078	3	marrow	marrow	NN
cord-022561-rv5j1201	1078	4	is	be	VBZ
cord-022561-rv5j1201	1078	5	hyperplastic	hyperplastic	JJ
cord-022561-rv5j1201	1078	6	and	and	CC
cord-022561-rv5j1201	1078	7	red	red	JJ
cord-022561-rv5j1201	1078	8	in	in	IN
cord-022561-rv5j1201	1078	9	the	the	DT
cord-022561-rv5j1201	1078	10	acute	acute	JJ
cord-022561-rv5j1201	1078	11	disease	disease	NN
cord-022561-rv5j1201	1078	12	but	but	CC
cord-022561-rv5j1201	1078	13	becomes	become	VBZ
cord-022561-rv5j1201	1078	14	hypoplastic	hypoplastic	JJ
cord-022561-rv5j1201	1078	15	and	and	CC
cord-022561-rv5j1201	1078	16	pale	pale	JJ
cord-022561-rv5j1201	1078	17	in	in	IN
cord-022561-rv5j1201	1078	18	dogs	dog	NNS
cord-022561-rv5j1201	1078	19	with	with	IN
cord-022561-rv5j1201	1078	20	chronic	chronic	JJ
cord-022561-rv5j1201	1078	21	E.	E.	NNP
cord-022561-rv5j1201	1078	22	canis	canis	NN
cord-022561-rv5j1201	1078	23	infection	infection	NN
cord-022561-rv5j1201	1078	24	.	.	.
cord-022561-rv5j1201	1079	1	Equine	equine	JJ
cord-022561-rv5j1201	1079	2	anaplasmosis	anaplasmosis	NN
cord-022561-rv5j1201	1079	3	is	be	VBZ
cord-022561-rv5j1201	1079	4	often	often	RB
cord-022561-rv5j1201	1079	5	mild	mild	JJ
cord-022561-rv5j1201	1079	6	but	but	CC
cord-022561-rv5j1201	1079	7	may	may	MD
cord-022561-rv5j1201	1079	8	cause	cause	VB
cord-022561-rv5j1201	1079	9	edema	edema	NN
cord-022561-rv5j1201	1079	10	and	and	CC
cord-022561-rv5j1201	1079	11	hemorrhages	hemorrhage	NNS
cord-022561-rv5j1201	1079	12	.	.	.
cord-022561-rv5j1201	1080	1	Disease	Disease	NNP
cord-022561-rv5j1201	1080	2	in	in	IN
cord-022561-rv5j1201	1080	3	cats	cat	NNS
cord-022561-rv5j1201	1080	4	is	be	VBZ
cord-022561-rv5j1201	1080	5	rare	rare	JJ
cord-022561-rv5j1201	1080	6	and	and	CC
cord-022561-rv5j1201	1080	7	poorly	poorly	RB
cord-022561-rv5j1201	1080	8	documented	document	VBN
cord-022561-rv5j1201	1080	9	.	.	.
cord-022561-rv5j1201	1081	1	Histologic	Histologic	NNP
cord-022561-rv5j1201	1081	2	findings	finding	NNS
cord-022561-rv5j1201	1081	3	include	include	VBP
cord-022561-rv5j1201	1081	4	generalized	generalize	VBN
cord-022561-rv5j1201	1081	5	perivascular	perivascular	JJ
cord-022561-rv5j1201	1081	6	plasma	plasma	NN
cord-022561-rv5j1201	1081	7	cell	cell	NN
cord-022561-rv5j1201	1081	8	infiltration	infiltration	NN
cord-022561-rv5j1201	1081	9	,	,	,
cord-022561-rv5j1201	1081	10	which	which	WDT
cord-022561-rv5j1201	1081	11	is	be	VBZ
cord-022561-rv5j1201	1081	12	most	most	RBS
cord-022561-rv5j1201	1081	13	pronounced	pronounce	VBN
cord-022561-rv5j1201	1081	14	in	in	IN
cord-022561-rv5j1201	1081	15	animals	animal	NNS
cord-022561-rv5j1201	1081	16	with	with	IN
cord-022561-rv5j1201	1081	17	chronic	chronic	JJ
cord-022561-rv5j1201	1081	18	disease	disease	NN
cord-022561-rv5j1201	1081	19	.	.	.
cord-022561-rv5j1201	1082	1	Multifocal	multifocal	JJ
cord-022561-rv5j1201	1082	2	,	,	,
cord-022561-rv5j1201	1082	3	nonsuppurative	nonsuppurative	NNP
cord-022561-rv5j1201	1082	4	meningoencephalitis	meningoencephalitis	NNP
cord-022561-rv5j1201	1082	5	,	,	,
cord-022561-rv5j1201	1082	6	interstitial	interstitial	JJ
cord-022561-rv5j1201	1082	7	pneumonia	pneumonia	NN
cord-022561-rv5j1201	1082	8	,	,	,
cord-022561-rv5j1201	1082	9	and	and	CC
cord-022561-rv5j1201	1082	10	glomerulonephritis	glomerulonephritis	NN
cord-022561-rv5j1201	1082	11	are	be	VBP
cord-022561-rv5j1201	1082	12	present	present	JJ
cord-022561-rv5j1201	1082	13	in	in	IN
cord-022561-rv5j1201	1082	14	most	most	JJS
cord-022561-rv5j1201	1082	15	dogs	dog	NNS
cord-022561-rv5j1201	1082	16	with	with	IN
cord-022561-rv5j1201	1082	17	the	the	DT
cord-022561-rv5j1201	1082	18	disease	disease	NN
cord-022561-rv5j1201	1082	19	.	.	.
cord-022561-rv5j1201	1083	1	Rickettsial	rickettsial	JJ
cord-022561-rv5j1201	1083	2	organisms	organism	NNS
cord-022561-rv5j1201	1083	3	are	be	VBP
cord-022561-rv5j1201	1083	4	difficult	difficult	JJ
cord-022561-rv5j1201	1083	5	to	to	TO
cord-022561-rv5j1201	1083	6	detect	detect	VB
cord-022561-rv5j1201	1083	7	histologically	histologically	RB
cord-022561-rv5j1201	1083	8	;	;	:
cord-022561-rv5j1201	1083	9	examination	examination	NN
cord-022561-rv5j1201	1083	10	of	of	IN
cord-022561-rv5j1201	1083	11	Wright	Wright	NNP
cord-022561-rv5j1201	1083	12	-	-	HYPH
cord-022561-rv5j1201	1083	13	Giemsa	Giemsa	NNP
cord-022561-rv5j1201	1083	14	-	-	HYPH
cord-022561-rv5j1201	1083	15	stained	stain	VBN
cord-022561-rv5j1201	1083	16	impression	impression	NN
cord-022561-rv5j1201	1083	17	smears	smear	NNS
cord-022561-rv5j1201	1083	18	of	of	IN
cord-022561-rv5j1201	1083	19	lung	lung	NN
cord-022561-rv5j1201	1083	20	,	,	,
cord-022561-rv5j1201	1083	21	liver	liver	NN
cord-022561-rv5j1201	1083	22	,	,	,
cord-022561-rv5j1201	1083	23	lymph	lymph	NN
cord-022561-rv5j1201	1083	24	nodes	node	NNS
cord-022561-rv5j1201	1083	25	,	,	,
cord-022561-rv5j1201	1083	26	and	and	CC
cord-022561-rv5j1201	1083	27	spleen	spleen	NN
cord-022561-rv5j1201	1083	28	is	be	VBZ
cord-022561-rv5j1201	1083	29	a	a	DT
cord-022561-rv5j1201	1083	30	more	more	RBR
cord-022561-rv5j1201	1083	31	effective	effective	JJ
cord-022561-rv5j1201	1083	32	method	method	NN
cord-022561-rv5j1201	1083	33	for	for	IN
cord-022561-rv5j1201	1083	34	detecting	detect	VBG
cord-022561-rv5j1201	1083	35	the	the	DT
cord-022561-rv5j1201	1083	36	morulae	morulae	NNP
cord-022561-rv5j1201	1083	37	within	within	IN
cord-022561-rv5j1201	1083	38	leukocytes	leukocyte	NNS
cord-022561-rv5j1201	1083	39	.	.	.
cord-022561-rv5j1201	1084	1	Heartwater	Heartwater	NNP
cord-022561-rv5j1201	1084	2	is	be	VBZ
cord-022561-rv5j1201	1084	3	often	often	RB
cord-022561-rv5j1201	1084	4	diagnosed	diagnose	VBN
cord-022561-rv5j1201	1084	5	by	by	IN
cord-022561-rv5j1201	1084	6	observing	observe	VBG
cord-022561-rv5j1201	1084	7	morulae	morulae	NNP
cord-022561-rv5j1201	1084	8	in	in	IN
cord-022561-rv5j1201	1084	9	endothelial	endothelial	JJ
cord-022561-rv5j1201	1084	10	cells	cell	NNS
cord-022561-rv5j1201	1084	11	of	of	IN
cord-022561-rv5j1201	1084	12	Giemsastained	Giemsastained	NNP
cord-022561-rv5j1201	1084	13	squash	squash	NN
cord-022561-rv5j1201	1084	14	preparations	preparation	NNS
cord-022561-rv5j1201	1084	15	of	of	IN
cord-022561-rv5j1201	1084	16	brain	brain	NN
cord-022561-rv5j1201	1084	17	.	.	.
cord-022561-rv5j1201	1085	1	Rickettsial	rickettsial	JJ
cord-022561-rv5j1201	1085	2	diseases	disease	NNS
cord-022561-rv5j1201	1085	3	are	be	VBP
cord-022561-rv5j1201	1085	4	often	often	RB
cord-022561-rv5j1201	1085	5	diagnosed	diagnose	VBN
cord-022561-rv5j1201	1085	6	on	on	IN
cord-022561-rv5j1201	1085	7	the	the	DT
cord-022561-rv5j1201	1085	8	basis	basis	NN
cord-022561-rv5j1201	1085	9	of	of	IN
cord-022561-rv5j1201	1085	10	serologic	serologic	JJ
cord-022561-rv5j1201	1085	11	testing	testing	NN
cord-022561-rv5j1201	1085	12	,	,	,
cord-022561-rv5j1201	1085	13	but	but	CC
cord-022561-rv5j1201	1085	14	PCR	PCR	NNP
cord-022561-rv5j1201	1085	15	testing	testing	NN
cord-022561-rv5j1201	1085	16	is	be	VBZ
cord-022561-rv5j1201	1085	17	more	more	RBR
cord-022561-rv5j1201	1085	18	sensitive	sensitive	JJ
cord-022561-rv5j1201	1085	19	.	.	.
cord-022561-rv5j1201	1086	1	Clostridial	Clostridial	NNP
cord-022561-rv5j1201	1086	2	Diseases	disease	NNS
cord-022561-rv5j1201	1086	3	.	.	.
cord-022561-rv5j1201	1087	1	Certain	certain	JJ
cord-022561-rv5j1201	1087	2	Clostridium	clostridium	NN
cord-022561-rv5j1201	1087	3	spp	spp	NN
cord-022561-rv5j1201	1087	4	.	.	.
cord-022561-rv5j1201	1088	1	may	may	MD
cord-022561-rv5j1201	1088	2	cause	cause	VB
cord-022561-rv5j1201	1088	3	potentially	potentially	RB
cord-022561-rv5j1201	1088	4	fatal	fatal	JJ
cord-022561-rv5j1201	1088	5	hemolytic	hemolytic	JJ
cord-022561-rv5j1201	1088	6	anemias	anemia	NNS
cord-022561-rv5j1201	1088	7	in	in	IN
cord-022561-rv5j1201	1088	8	animals	animal	NNS
cord-022561-rv5j1201	1088	9	;	;	:
cord-022561-rv5j1201	1088	10	nonhemolytic	nonhemolytic	JJ
cord-022561-rv5j1201	1088	11	lesions	lesion	NNS
cord-022561-rv5j1201	1088	12	are	be	VBP
cord-022561-rv5j1201	1088	13	presented	present	VBN
cord-022561-rv5j1201	1088	14	elsewhere	elsewhere	RB
cord-022561-rv5j1201	1088	15	(	(	-LRB-
cord-022561-rv5j1201	1088	16	see	see	VB
cord-022561-rv5j1201	1088	17	Chapters	Chapters	NNPS
cord-022561-rv5j1201	1088	18	4	4	CD
cord-022561-rv5j1201	1088	19	,	,	,
cord-022561-rv5j1201	1088	20	7	7	CD
cord-022561-rv5j1201	1088	21	,	,	,
cord-022561-rv5j1201	1088	22	8	8	CD
cord-022561-rv5j1201	1088	23	,	,	,
cord-022561-rv5j1201	1088	24	and	and	CC
cord-022561-rv5j1201	1088	25	19	19	CD
cord-022561-rv5j1201	1088	26	)	)	-RRB-
cord-022561-rv5j1201	1088	27	.	.	.
cord-022561-rv5j1201	1089	1	Clostridium	clostridium	NN
cord-022561-rv5j1201	1089	2	haemolyticum	haemolyticum	NN
cord-022561-rv5j1201	1089	3	and	and	CC
cord-022561-rv5j1201	1089	4	Clostridium	Clostridium	NNP
cord-022561-rv5j1201	1089	5	novyi	novyi	NNS
cord-022561-rv5j1201	1089	6	type	type	NN
cord-022561-rv5j1201	1089	7	D	d	NN
cord-022561-rv5j1201	1089	8	cause	cause	VBP
cord-022561-rv5j1201	1089	9	the	the	DT
cord-022561-rv5j1201	1089	10	disease	disease	NN
cord-022561-rv5j1201	1089	11	in	in	IN
cord-022561-rv5j1201	1089	12	cattle	cattle	NNS
cord-022561-rv5j1201	1089	13	known	know	VBN
cord-022561-rv5j1201	1089	14	as	as	IN
cord-022561-rv5j1201	1089	15	bacillary	bacillary	NNP
cord-022561-rv5j1201	1089	16	hemoglobinuria	hemoglobinuria	NNP
cord-022561-rv5j1201	1089	17	.	.	.
cord-022561-rv5j1201	1090	1	(	(	-LRB-
cord-022561-rv5j1201	1090	2	The	the	DT
cord-022561-rv5j1201	1090	3	phrase	phrase	NN
cord-022561-rv5j1201	1090	4	"	"	``
cord-022561-rv5j1201	1090	5	red	red	JJ
cord-022561-rv5j1201	1090	6	water	water	NN
cord-022561-rv5j1201	1090	7	"	"	''
cord-022561-rv5j1201	1090	8	has	have	VBZ
cord-022561-rv5j1201	1090	9	also	also	RB
cord-022561-rv5j1201	1090	10	been	be	VBN
cord-022561-rv5j1201	1090	11	used	use	VBN
cord-022561-rv5j1201	1090	12	for	for	IN
cord-022561-rv5j1201	1090	13	this	this	DT
cord-022561-rv5j1201	1090	14	disease	disease	NN
cord-022561-rv5j1201	1090	15	and	and	CC
cord-022561-rv5j1201	1090	16	for	for	IN
cord-022561-rv5j1201	1090	17	hemolytic	hemolytic	JJ
cord-022561-rv5j1201	1090	18	anemias	anemia	NNS
cord-022561-rv5j1201	1090	19	in	in	IN
cord-022561-rv5j1201	1090	20	cattle	cattle	NNS
cord-022561-rv5j1201	1090	21	caused	cause	VBN
cord-022561-rv5j1201	1090	22	by	by	IN
cord-022561-rv5j1201	1090	23	Babesia	Babesia	NNP
cord-022561-rv5j1201	1090	24	spp	spp	NNS
cord-022561-rv5j1201	1090	25	.	.	.
cord-022561-rv5j1201	1090	26	)	)	-RRB-
cord-022561-rv5j1201	1091	1	Similar	similar	JJ
cord-022561-rv5j1201	1091	2	naturally	naturally	RB
cord-022561-rv5j1201	1091	3	occurring	occur	VBG
cord-022561-rv5j1201	1091	4	disease	disease	NN
cord-022561-rv5j1201	1091	5	has	have	VBZ
cord-022561-rv5j1201	1091	6	been	be	VBN
cord-022561-rv5j1201	1091	7	reported	report	VBN
cord-022561-rv5j1201	1091	8	in	in	IN
cord-022561-rv5j1201	1091	9	sheep	sheep	NNS
cord-022561-rv5j1201	1091	10	.	.	.
cord-022561-rv5j1201	1092	1	In	in	IN
cord-022561-rv5j1201	1092	2	cattle	cattle	NNS
cord-022561-rv5j1201	1092	3	the	the	DT
cord-022561-rv5j1201	1092	4	disease	disease	NN
cord-022561-rv5j1201	1092	5	is	be	VBZ
cord-022561-rv5j1201	1092	6	caused	cause	VBN
cord-022561-rv5j1201	1092	7	by	by	IN
cord-022561-rv5j1201	1092	8	liver	liver	NN
cord-022561-rv5j1201	1092	9	fluke	fluke	NN
cord-022561-rv5j1201	1092	10	(	(	-LRB-
cord-022561-rv5j1201	1092	11	Fasciola	Fasciola	NNP
cord-022561-rv5j1201	1092	12	hepatica	hepatica	NNP
cord-022561-rv5j1201	1092	13	)	)	-RRB-
cord-022561-rv5j1201	1092	14	migration	migration	NN
cord-022561-rv5j1201	1092	15	in	in	IN
cord-022561-rv5j1201	1092	16	susceptible	susceptible	JJ
cord-022561-rv5j1201	1092	17	animals	animal	NNS
cord-022561-rv5j1201	1092	18	.	.	.
cord-022561-rv5j1201	1093	1	Ingested	ingested	JJ
cord-022561-rv5j1201	1093	2	clostridial	clostridial	JJ
cord-022561-rv5j1201	1093	3	spores	spore	NNS
cord-022561-rv5j1201	1093	4	may	may	MD
cord-022561-rv5j1201	1093	5	live	live	VB
cord-022561-rv5j1201	1093	6	in	in	IN
cord-022561-rv5j1201	1093	7	Kupffer	Kupffer	NNP
cord-022561-rv5j1201	1093	8	cells	cell	NNS
cord-022561-rv5j1201	1093	9	for	for	IN
cord-022561-rv5j1201	1093	10	a	a	DT
cord-022561-rv5j1201	1093	11	long	long	JJ
cord-022561-rv5j1201	1093	12	time	time	NN
cord-022561-rv5j1201	1093	13	without	without	IN
cord-022561-rv5j1201	1093	14	causing	cause	VBG
cord-022561-rv5j1201	1093	15	disease	disease	NN
cord-022561-rv5j1201	1093	16	.	.	.
cord-022561-rv5j1201	1094	1	However	however	RB
cord-022561-rv5j1201	1094	2	,	,	,
cord-022561-rv5j1201	1094	3	when	when	WRB
cord-022561-rv5j1201	1094	4	migrating	migrate	VBG
cord-022561-rv5j1201	1094	5	flukes	fluke	NNS
cord-022561-rv5j1201	1094	6	cause	cause	VBP
cord-022561-rv5j1201	1094	7	hepatic	hepatic	JJ
cord-022561-rv5j1201	1094	8	necrosis	necrosis	NN
cord-022561-rv5j1201	1094	9	,	,	,
cord-022561-rv5j1201	1094	10	the	the	DT
cord-022561-rv5j1201	1094	11	resulting	result	VBG
cord-022561-rv5j1201	1094	12	anaerobic	anaerobic	JJ
cord-022561-rv5j1201	1094	13	environment	environment	NN
cord-022561-rv5j1201	1094	14	stimulates	stimulate	VBZ
cord-022561-rv5j1201	1094	15	the	the	DT
cord-022561-rv5j1201	1094	16	clostridial	clostridial	JJ
cord-022561-rv5j1201	1094	17	organisms	organism	NNS
cord-022561-rv5j1201	1094	18	to	to	TO
cord-022561-rv5j1201	1094	19	proliferate	proliferate	VB
cord-022561-rv5j1201	1094	20	and	and	CC
cord-022561-rv5j1201	1094	21	elaborate	elaborate	VB
cord-022561-rv5j1201	1094	22	their	-PRON-	PRP$
cord-022561-rv5j1201	1094	23	hemolytic	hemolytic	JJ
cord-022561-rv5j1201	1094	24	toxins	toxin	NNS
cord-022561-rv5j1201	1094	25	,	,	,
cord-022561-rv5j1201	1094	26	causing	cause	VBG
cord-022561-rv5j1201	1094	27	additional	additional	JJ
cord-022561-rv5j1201	1094	28	hepatic	hepatic	JJ
cord-022561-rv5j1201	1094	29	necrosis	necrosis	NN
cord-022561-rv5j1201	1094	30	.	.	.
cord-022561-rv5j1201	1095	1	The	the	DT
cord-022561-rv5j1201	1095	2	mechanism	mechanism	NN
cord-022561-rv5j1201	1095	3	of	of	IN
cord-022561-rv5j1201	1095	4	hemolysis	hemolysis	NN
cord-022561-rv5j1201	1095	5	involves	involve	VBZ
cord-022561-rv5j1201	1095	6	a	a	DT
cord-022561-rv5j1201	1095	7	bacterial	bacterial	JJ
cord-022561-rv5j1201	1095	8	β	β	NN
cord-022561-rv5j1201	1095	9	-	-	HYPH
cord-022561-rv5j1201	1095	10	toxin	toxin	NN
cord-022561-rv5j1201	1095	11	(	(	-LRB-
cord-022561-rv5j1201	1095	12	phospholipase	phospholipase	NN
cord-022561-rv5j1201	1095	13	C	c	NN
cord-022561-rv5j1201	1095	14	or	or	CC
cord-022561-rv5j1201	1095	15	lecithinase	lecithinase	NNP
cord-022561-rv5j1201	1095	16	)	)	-RRB-
cord-022561-rv5j1201	1095	17	,	,	,
cord-022561-rv5j1201	1095	18	which	which	WDT
cord-022561-rv5j1201	1095	19	enzymatically	enzymatically	RB
cord-022561-rv5j1201	1095	20	degrades	degrade	VBZ
cord-022561-rv5j1201	1095	21	cell	cell	NN
cord-022561-rv5j1201	1095	22	membranes	membrane	NNS
cord-022561-rv5j1201	1095	23	,	,	,
cord-022561-rv5j1201	1095	24	causing	cause	VBG
cord-022561-rv5j1201	1095	25	acute	acute	JJ
cord-022561-rv5j1201	1095	26	intravascular	intravascular	JJ
cord-022561-rv5j1201	1095	27	hemolysis	hemolysis	NN
cord-022561-rv5j1201	1095	28	.	.	.
cord-022561-rv5j1201	1096	1	Bacillary	Bacillary	NNP
cord-022561-rv5j1201	1096	2	hemoglobinuria	hemoglobinuria	NNP
cord-022561-rv5j1201	1096	3	also	also	RB
cord-022561-rv5j1201	1096	4	occurs	occur	VBZ
cord-022561-rv5j1201	1096	5	with	with	IN
cord-022561-rv5j1201	1096	6	liver	liver	NN
cord-022561-rv5j1201	1096	7	biopsies	biopsy	NNS
cord-022561-rv5j1201	1096	8	in	in	IN
cord-022561-rv5j1201	1096	9	calves	calf	NNS
cord-022561-rv5j1201	1096	10	.	.	.
cord-022561-rv5j1201	1097	1	Clostridium	clostridium	NN
cord-022561-rv5j1201	1097	2	perfringens	perfringens	NN
cord-022561-rv5j1201	1097	3	type	type	NN
cord-022561-rv5j1201	1097	4	A	a	NN
cord-022561-rv5j1201	1097	5	causes	cause	VBZ
cord-022561-rv5j1201	1097	6	intravascular	intravascular	JJ
cord-022561-rv5j1201	1097	7	hemolytic	hemolytic	JJ
cord-022561-rv5j1201	1097	8	anemia	anemia	NN
cord-022561-rv5j1201	1097	9	in	in	IN
cord-022561-rv5j1201	1097	10	lambs	lamb	NNS
cord-022561-rv5j1201	1097	11	and	and	CC
cord-022561-rv5j1201	1097	12	calves	calf	NNS
cord-022561-rv5j1201	1097	13	-	-	:
cord-022561-rv5j1201	1097	14	a	a	DT
cord-022561-rv5j1201	1097	15	condition	condition	NN
cord-022561-rv5j1201	1097	16	known	know	VBN
cord-022561-rv5j1201	1097	17	as	as	IN
cord-022561-rv5j1201	1097	18	yellow	yellow	JJ
cord-022561-rv5j1201	1097	19	lamb	lamb	NN
cord-022561-rv5j1201	1097	20	disease	disease	NN
cord-022561-rv5j1201	1097	21	,	,	,
cord-022561-rv5j1201	1097	22	yellows	yellow	NNS
cord-022561-rv5j1201	1097	23	,	,	,
cord-022561-rv5j1201	1097	24	or	or	CC
cord-022561-rv5j1201	1097	25	enterotoxemic	enterotoxemic	JJ
cord-022561-rv5j1201	1097	26	jaundice	jaundice	NN
cord-022561-rv5j1201	1097	27	because	because	IN
cord-022561-rv5j1201	1097	28	of	of	IN
cord-022561-rv5j1201	1097	29	the	the	DT
cord-022561-rv5j1201	1097	30	characteristic	characteristic	JJ
cord-022561-rv5j1201	1097	31	icterus	icterus	NN
cord-022561-rv5j1201	1097	32	.	.	.
cord-022561-rv5j1201	1098	1	The	the	DT
cord-022561-rv5j1201	1098	2	organism	organism	NN
cord-022561-rv5j1201	1098	3	is	be	VBZ
cord-022561-rv5j1201	1098	4	a	a	DT
cord-022561-rv5j1201	1098	5	normal	normal	JJ
cord-022561-rv5j1201	1098	6	inhabitant	inhabitant	NN
cord-022561-rv5j1201	1098	7	of	of	IN
cord-022561-rv5j1201	1098	8	the	the	DT
cord-022561-rv5j1201	1098	9	gastrointestinal	gastrointestinal	JJ
cord-022561-rv5j1201	1098	10	tract	tract	NN
cord-022561-rv5j1201	1098	11	in	in	IN
cord-022561-rv5j1201	1098	12	these	these	DT
cord-022561-rv5j1201	1098	13	animals	animal	NNS
cord-022561-rv5j1201	1098	14	but	but	CC
cord-022561-rv5j1201	1098	15	may	may	MD
cord-022561-rv5j1201	1098	16	proliferate	proliferate	VB
cord-022561-rv5j1201	1098	17	abnormally	abnormally	RB
cord-022561-rv5j1201	1098	18	in	in	IN
cord-022561-rv5j1201	1098	19	response	response	NN
cord-022561-rv5j1201	1098	20	to	to	IN
cord-022561-rv5j1201	1098	21	some	some	DT
cord-022561-rv5j1201	1098	22	diets	diet	NNS
cord-022561-rv5j1201	1098	23	.	.	.
cord-022561-rv5j1201	1099	1	C.	C.	NNP
cord-022561-rv5j1201	1099	2	perfringens	perfringens	NN
cord-022561-rv5j1201	1099	3	causes	cause	VBZ
cord-022561-rv5j1201	1099	4	intravascular	intravascular	JJ
cord-022561-rv5j1201	1099	5	hemolytic	hemolytic	JJ
cord-022561-rv5j1201	1099	6	anemia	anemia	NN
cord-022561-rv5j1201	1099	7	in	in	IN
cord-022561-rv5j1201	1099	8	horses	horse	NNS
cord-022561-rv5j1201	1099	9	with	with	IN
cord-022561-rv5j1201	1099	10	clostridial	clostridial	JJ
cord-022561-rv5j1201	1099	11	abscesses	abscess	NNS
cord-022561-rv5j1201	1099	12	,	,	,
cord-022561-rv5j1201	1099	13	and	and	CC
cord-022561-rv5j1201	1099	14	clostridial	clostridial	JJ
cord-022561-rv5j1201	1099	15	mastitis	mastitis	NN
cord-022561-rv5j1201	1099	16	in	in	IN
cord-022561-rv5j1201	1099	17	ewes	ewe	NNS
cord-022561-rv5j1201	1099	18	.	.	.
cord-022561-rv5j1201	1100	1	C.	C.	NNP
cord-022561-rv5j1201	1100	2	perfringens	perfringens	NN
cord-022561-rv5j1201	1100	3	type	type	NN
cord-022561-rv5j1201	1100	4	A	a	NN
cord-022561-rv5j1201	1100	5	produces	produce	VBZ
cord-022561-rv5j1201	1100	6	hemolytic	hemolytic	JJ
cord-022561-rv5j1201	1100	7	α	α	NN
cord-022561-rv5j1201	1100	8	-	-	HYPH
cord-022561-rv5j1201	1100	9	toxin	toxin	NN
cord-022561-rv5j1201	1100	10	,	,	,
cord-022561-rv5j1201	1100	11	which	which	WDT
cord-022561-rv5j1201	1100	12	also	also	RB
cord-022561-rv5j1201	1100	13	has	have	VBZ
cord-022561-rv5j1201	1100	14	phospholipase	phospholipase	NN
cord-022561-rv5j1201	1100	15	C	c	NN
cord-022561-rv5j1201	1100	16	activity	activity	NN
cord-022561-rv5j1201	1100	17	.	.	.
cord-022561-rv5j1201	1101	1	Leptospirosis	leptospirosis	NN
cord-022561-rv5j1201	1101	2	.	.	.
cord-022561-rv5j1201	1102	1	Leptospirosis	leptospirosis	NN
cord-022561-rv5j1201	1102	2	is	be	VBZ
cord-022561-rv5j1201	1102	3	recognized	recognize	VBN
cord-022561-rv5j1201	1102	4	as	as	IN
cord-022561-rv5j1201	1102	5	a	a	DT
cord-022561-rv5j1201	1102	6	cause	cause	NN
cord-022561-rv5j1201	1102	7	of	of	IN
cord-022561-rv5j1201	1102	8	hemolytic	hemolytic	JJ
cord-022561-rv5j1201	1102	9	anemia	anemia	NN
cord-022561-rv5j1201	1102	10	in	in	IN
cord-022561-rv5j1201	1102	11	calves	calf	NNS
cord-022561-rv5j1201	1102	12	,	,	,
cord-022561-rv5j1201	1102	13	lambs	lamb	NNS
cord-022561-rv5j1201	1102	14	,	,	,
cord-022561-rv5j1201	1102	15	and	and	CC
cord-022561-rv5j1201	1102	16	pigs	pig	NNS
cord-022561-rv5j1201	1102	17	.	.	.
cord-022561-rv5j1201	1103	1	Specific	specific	JJ
cord-022561-rv5j1201	1103	2	leptospiral	leptospiral	JJ
cord-022561-rv5j1201	1103	3	organisms	organism	NNS
cord-022561-rv5j1201	1103	4	that	that	WDT
cord-022561-rv5j1201	1103	5	cause	cause	VBP
cord-022561-rv5j1201	1103	6	hemolytic	hemolytic	JJ
cord-022561-rv5j1201	1103	7	disease	disease	NN
cord-022561-rv5j1201	1103	8	include	include	VBP
cord-022561-rv5j1201	1103	9	Leptospira	Leptospira	NNP
cord-022561-rv5j1201	1103	10	interrogans	interrogans	NNPS
cord-022561-rv5j1201	1103	11	serovars	serovars	NNPS
cord-022561-rv5j1201	1103	12	pomona	pomona	NNP
cord-022561-rv5j1201	1103	13	and	and	CC
cord-022561-rv5j1201	1103	14	ictohaemorrhagiae	ictohaemorrhagiae	NNP
cord-022561-rv5j1201	1103	15	.	.	.
cord-022561-rv5j1201	1104	1	Leptospira	Leptospira	NNP
cord-022561-rv5j1201	1104	2	organisms	organism	NNS
cord-022561-rv5j1201	1104	3	are	be	VBP
cord-022561-rv5j1201	1104	4	ubiquitous	ubiquitous	JJ
cord-022561-rv5j1201	1104	5	in	in	IN
cord-022561-rv5j1201	1104	6	the	the	DT
cord-022561-rv5j1201	1104	7	environment	environment	NN
cord-022561-rv5j1201	1104	8	.	.	.
cord-022561-rv5j1201	1105	1	Infection	infection	NN
cord-022561-rv5j1201	1105	2	occurs	occur	VBZ
cord-022561-rv5j1201	1105	3	percutaneously	percutaneously	NN
cord-022561-rv5j1201	1105	4	and	and	CC
cord-022561-rv5j1201	1105	5	via	via	IN
cord-022561-rv5j1201	1105	6	mucosal	mucosal	JJ
cord-022561-rv5j1201	1105	7	surfaces	surface	NNS
cord-022561-rv5j1201	1105	8	and	and	CC
cord-022561-rv5j1201	1105	9	is	be	VBZ
cord-022561-rv5j1201	1105	10	followed	follow	VBN
cord-022561-rv5j1201	1105	11	by	by	IN
cord-022561-rv5j1201	1105	12	leptospiremia	leptospiremia	NN
cord-022561-rv5j1201	1105	13	;	;	:
cord-022561-rv5j1201	1105	14	organisms	organism	NNS
cord-022561-rv5j1201	1105	15	then	then	RB
cord-022561-rv5j1201	1105	16	localize	localize	VBP
cord-022561-rv5j1201	1105	17	preferentially	preferentially	RB
cord-022561-rv5j1201	1105	18	in	in	IN
cord-022561-rv5j1201	1105	19	certain	certain	JJ
cord-022561-rv5j1201	1105	20	tissues	tissue	NNS
cord-022561-rv5j1201	1105	21	(	(	-LRB-
cord-022561-rv5j1201	1105	22	e.g.	e.g.	RB
cord-022561-rv5j1201	1105	23	,	,	,
cord-022561-rv5j1201	1105	24	kidney	kidney	NN
cord-022561-rv5j1201	1105	25	,	,	,
cord-022561-rv5j1201	1105	26	liver	liver	NN
cord-022561-rv5j1201	1105	27	,	,	,
cord-022561-rv5j1201	1105	28	and	and	CC
cord-022561-rv5j1201	1105	29	pregnant	pregnant	JJ
cord-022561-rv5j1201	1105	30	uterus	uterus	NN
cord-022561-rv5j1201	1105	31	)	)	-RRB-
cord-022561-rv5j1201	1105	32	.	.	.
cord-022561-rv5j1201	1106	1	Proposed	propose	VBN
cord-022561-rv5j1201	1106	2	mechanisms	mechanism	NNS
cord-022561-rv5j1201	1106	3	of	of	IN
cord-022561-rv5j1201	1106	4	hemolytic	hemolytic	JJ
cord-022561-rv5j1201	1106	5	disease	disease	NN
cord-022561-rv5j1201	1106	6	include	include	VBP
cord-022561-rv5j1201	1106	7	immune	immune	NN
cord-022561-rv5j1201	1106	8	-	-	HYPH
cord-022561-rv5j1201	1106	9	mediated	mediate	VBN
cord-022561-rv5j1201	1106	10	(	(	-LRB-
cord-022561-rv5j1201	1106	11	immunoglobulin	immunoglobulin	NN
cord-022561-rv5j1201	1106	12	M	M	NNP
cord-022561-rv5j1201	1106	13	[	[	-LRB-
cord-022561-rv5j1201	1106	14	IgM	IgM	NNP
cord-022561-rv5j1201	1106	15	]	]	-RRB-
cord-022561-rv5j1201	1106	16	cold	cold	NNP
cord-022561-rv5j1201	1106	17	agglutinin	agglutinin	NNP
cord-022561-rv5j1201	1106	18	)	)	-RRB-
cord-022561-rv5j1201	1107	1	extravascular	extravascular	JJ
cord-022561-rv5j1201	1107	2	hemolysis	hemolysis	NN
cord-022561-rv5j1201	1107	3	and	and	CC
cord-022561-rv5j1201	1107	4	enzymatic	enzymatic	JJ
cord-022561-rv5j1201	1107	5	(	(	-LRB-
cord-022561-rv5j1201	1107	6	phospholipase	phospholipase	NN
cord-022561-rv5j1201	1107	7	produced	produce	VBN
cord-022561-rv5j1201	1107	8	by	by	IN
cord-022561-rv5j1201	1107	9	the	the	DT
cord-022561-rv5j1201	1107	10	organism	organism	NN
cord-022561-rv5j1201	1107	11	)	)	-RRB-
cord-022561-rv5j1201	1107	12	intravascular	intravascular	JJ
cord-022561-rv5j1201	1107	13	hemolysis	hemolysis	NN
cord-022561-rv5j1201	1107	14	.	.	.
cord-022561-rv5j1201	1108	1	Leptospirosis	leptospirosis	NN
cord-022561-rv5j1201	1108	2	can	can	MD
cord-022561-rv5j1201	1108	3	also	also	RB
cord-022561-rv5j1201	1108	4	cause	cause	VB
cord-022561-rv5j1201	1108	5	many	many	JJ
cord-022561-rv5j1201	1108	6	disease	disease	NN
cord-022561-rv5j1201	1108	7	manifestations	manifestation	NNS
cord-022561-rv5j1201	1108	8	besides	besides	IN
cord-022561-rv5j1201	1108	9	hemolysis	hemolysis	NN
cord-022561-rv5j1201	1108	10	(	(	-LRB-
cord-022561-rv5j1201	1108	11	e.g.	e.g.	RB
cord-022561-rv5j1201	1108	12	,	,	,
cord-022561-rv5j1201	1108	13	renal	renal	JJ
cord-022561-rv5j1201	1108	14	failure	failure	NN
cord-022561-rv5j1201	1108	15	,	,	,
cord-022561-rv5j1201	1108	16	liver	liver	NN
cord-022561-rv5j1201	1108	17	failure	failure	NN
cord-022561-rv5j1201	1108	18	,	,	,
cord-022561-rv5j1201	1108	19	abortion	abortion	NN
cord-022561-rv5j1201	1108	20	,	,	,
cord-022561-rv5j1201	1108	21	and	and	CC
cord-022561-rv5j1201	1108	22	other	other	JJ
cord-022561-rv5j1201	1108	23	conditions	condition	NNS
cord-022561-rv5j1201	1108	24	)	)	-RRB-
cord-022561-rv5j1201	1108	25	that	that	WDT
cord-022561-rv5j1201	1108	26	are	be	VBP
cord-022561-rv5j1201	1108	27	not	not	RB
cord-022561-rv5j1201	1108	28	discussed	discuss	VBN
cord-022561-rv5j1201	1108	29	here	here	RB
cord-022561-rv5j1201	1108	30	.	.	.
cord-022561-rv5j1201	1109	1	primary	primary	JJ
cord-022561-rv5j1201	1109	2	immune	immune	NN
cord-022561-rv5j1201	1109	3	-	-	HYPH
cord-022561-rv5j1201	1109	4	mediated	mediate	VBN
cord-022561-rv5j1201	1109	5	hemolytic	hemolytic	JJ
cord-022561-rv5j1201	1109	6	anemia	anemia	NN
cord-022561-rv5j1201	1109	7	or	or	CC
cord-022561-rv5j1201	1109	8	autoimmune	autoimmune	JJ
cord-022561-rv5j1201	1109	9	hemolytic	hemolytic	JJ
cord-022561-rv5j1201	1109	10	anemia	anemia	NN
cord-022561-rv5j1201	1109	11	)	)	-RRB-
cord-022561-rv5j1201	1109	12	or	or	CC
cord-022561-rv5j1201	1109	13	secondary	secondary	JJ
cord-022561-rv5j1201	1109	14	to	to	IN
cord-022561-rv5j1201	1109	15	a	a	DT
cord-022561-rv5j1201	1109	16	known	know	VBN
cord-022561-rv5j1201	1109	17	initiator	initiator	NN
cord-022561-rv5j1201	1109	18	,	,	,
cord-022561-rv5j1201	1109	19	termed	term	VBD
cord-022561-rv5j1201	1109	20	secondary	secondary	JJ
cord-022561-rv5j1201	1109	21	immune	immune	NN
cord-022561-rv5j1201	1109	22	-	-	HYPH
cord-022561-rv5j1201	1109	23	mediated	mediate	VBN
cord-022561-rv5j1201	1109	24	hemolytic	hemolytic	JJ
cord-022561-rv5j1201	1109	25	anemia	anemia	NN
cord-022561-rv5j1201	1109	26	.	.	.
cord-022561-rv5j1201	1110	1	Although	although	IN
cord-022561-rv5j1201	1110	2	the	the	DT
cord-022561-rv5j1201	1110	3	cause	cause	NN
cord-022561-rv5j1201	1110	4	of	of	IN
cord-022561-rv5j1201	1110	5	idiopathic	idiopathic	JJ
cord-022561-rv5j1201	1110	6	immune	immune	NN
cord-022561-rv5j1201	1110	7	-	-	HYPH
cord-022561-rv5j1201	1110	8	mediated	mediate	VBN
cord-022561-rv5j1201	1110	9	hemolytic	hemolytic	JJ
cord-022561-rv5j1201	1110	10	anemia	anemia	NN
cord-022561-rv5j1201	1110	11	is	be	VBZ
cord-022561-rv5j1201	1110	12	unknown	unknown	JJ
cord-022561-rv5j1201	1110	13	,	,	,
cord-022561-rv5j1201	1110	14	certain	certain	JJ
cord-022561-rv5j1201	1110	15	dog	dog	NN
cord-022561-rv5j1201	1110	16	breeds	breed	NNS
cord-022561-rv5j1201	1110	17	(	(	-LRB-
cord-022561-rv5j1201	1110	18	e.g.	e.g.	RB
cord-022561-rv5j1201	1110	19	,	,	,
cord-022561-rv5j1201	1110	20	cocker	cocker	NN
cord-022561-rv5j1201	1110	21	spaniels	spaniel	NNS
cord-022561-rv5j1201	1110	22	)	)	-RRB-
cord-022561-rv5j1201	1110	23	are	be	VBP
cord-022561-rv5j1201	1110	24	predisposed	predisposed	JJ
cord-022561-rv5j1201	1110	25	to	to	IN
cord-022561-rv5j1201	1110	26	developing	develop	VBG
cord-022561-rv5j1201	1110	27	disease	disease	NN
cord-022561-rv5j1201	1110	28	,	,	,
cord-022561-rv5j1201	1110	29	suggesting	suggest	VBG
cord-022561-rv5j1201	1110	30	the	the	DT
cord-022561-rv5j1201	1110	31	possibility	possibility	NN
cord-022561-rv5j1201	1110	32	of	of	IN
cord-022561-rv5j1201	1110	33	a	a	DT
cord-022561-rv5j1201	1110	34	genetic	genetic	JJ
cord-022561-rv5j1201	1110	35	component	component	NN
cord-022561-rv5j1201	1110	36	.	.	.
cord-022561-rv5j1201	1111	1	Causes	cause	NNS
cord-022561-rv5j1201	1111	2	of	of	IN
cord-022561-rv5j1201	1111	3	secondary	secondary	JJ
cord-022561-rv5j1201	1111	4	immune	immune	NN
cord-022561-rv5j1201	1111	5	-	-	HYPH
cord-022561-rv5j1201	1111	6	mediated	mediate	VBN
cord-022561-rv5j1201	1111	7	hemolytic	hemolytic	JJ
cord-022561-rv5j1201	1111	8	anemia	anemia	NN
cord-022561-rv5j1201	1111	9	include	include	VBP
cord-022561-rv5j1201	1111	10	certain	certain	JJ
cord-022561-rv5j1201	1111	11	infections	infection	NNS
cord-022561-rv5j1201	1111	12	(	(	-LRB-
cord-022561-rv5j1201	1111	13	e.g.	e.g.	RB
cord-022561-rv5j1201	1111	14	,	,	,
cord-022561-rv5j1201	1111	15	hemoplasmosis	hemoplasmosis	NN
cord-022561-rv5j1201	1111	16	,	,	,
cord-022561-rv5j1201	1111	17	babesiosis	babesiosi	NNS
cord-022561-rv5j1201	1111	18	,	,	,
cord-022561-rv5j1201	1111	19	and	and	CC
cord-022561-rv5j1201	1111	20	theileriosis	theileriosis	NNP
cord-022561-rv5j1201	1111	21	)	)	-RRB-
cord-022561-rv5j1201	1111	22	,	,	,
cord-022561-rv5j1201	1111	23	drugs	drug	NNS
cord-022561-rv5j1201	1111	24	(	(	-LRB-
cord-022561-rv5j1201	1111	25	e.g.	e.g.	RB
cord-022561-rv5j1201	1111	26	,	,	,
cord-022561-rv5j1201	1111	27	cephalosporins	cephalosporin	NNS
cord-022561-rv5j1201	1111	28	,	,	,
cord-022561-rv5j1201	1111	29	penicillin	penicillin	NN
cord-022561-rv5j1201	1111	30	,	,	,
cord-022561-rv5j1201	1111	31	and	and	CC
cord-022561-rv5j1201	1111	32	sulfonamides	sulfonamides	NNPS
cord-022561-rv5j1201	1111	33	)	)	-RRB-
cord-022561-rv5j1201	1111	34	,	,	,
cord-022561-rv5j1201	1111	35	vaccines	vaccine	NNS
cord-022561-rv5j1201	1111	36	,	,	,
cord-022561-rv5j1201	1111	37	and	and	CC
cord-022561-rv5j1201	1111	38	envenomations	envenomations	NNP
cord-022561-rv5j1201	1111	39	(	(	-LRB-
cord-022561-rv5j1201	1111	40	e.g.	e.g.	RB
cord-022561-rv5j1201	1111	41	,	,	,
cord-022561-rv5j1201	1111	42	bee	bee	NN
cord-022561-rv5j1201	1111	43	stings	sting	NNS
cord-022561-rv5j1201	1111	44	)	)	-RRB-
cord-022561-rv5j1201	1111	45	.	.	.
cord-022561-rv5j1201	1112	1	Immune	immune	NN
cord-022561-rv5j1201	1112	2	-	-	HYPH
cord-022561-rv5j1201	1112	3	mediated	mediate	VBN
cord-022561-rv5j1201	1112	4	hemolysis	hemolysis	NN
cord-022561-rv5j1201	1112	5	directed	direct	VBN
cord-022561-rv5j1201	1112	6	at	at	IN
cord-022561-rv5j1201	1112	7	nonself	nonself	NN
cord-022561-rv5j1201	1112	8	antigens	antigen	NNS
cord-022561-rv5j1201	1112	9	,	,	,
cord-022561-rv5j1201	1112	10	such	such	JJ
cord-022561-rv5j1201	1112	11	as	as	IN
cord-022561-rv5j1201	1112	12	in	in	IN
cord-022561-rv5j1201	1112	13	neonatal	neonatal	JJ
cord-022561-rv5j1201	1112	14	isoerythrolysis	isoerythrolysis	NN
cord-022561-rv5j1201	1112	15	,	,	,
cord-022561-rv5j1201	1112	16	is	be	VBZ
cord-022561-rv5j1201	1112	17	presented	present	VBN
cord-022561-rv5j1201	1112	18	later	later	RB
cord-022561-rv5j1201	1112	19	.	.	.
cord-022561-rv5j1201	1113	1	In	in	IN
cord-022561-rv5j1201	1113	2	most	most	JJS
cord-022561-rv5j1201	1113	3	cases	case	NNS
cord-022561-rv5j1201	1113	4	of	of	IN
cord-022561-rv5j1201	1113	5	idiopathic	idiopathic	JJ
cord-022561-rv5j1201	1113	6	immune	immune	NN
cord-022561-rv5j1201	1113	7	-	-	HYPH
cord-022561-rv5j1201	1113	8	mediated	mediate	VBN
cord-022561-rv5j1201	1113	9	hemolytic	hemolytic	JJ
cord-022561-rv5j1201	1113	10	anemia	anemia	NN
cord-022561-rv5j1201	1113	11	,	,	,
cord-022561-rv5j1201	1113	12	the	the	DT
cord-022561-rv5j1201	1113	13	reactive	reactive	JJ
cord-022561-rv5j1201	1113	14	antibody	antibody	NN
cord-022561-rv5j1201	1113	15	is	be	VBZ
cord-022561-rv5j1201	1113	16	IgG	IgG	NNP
cord-022561-rv5j1201	1113	17	,	,	,
cord-022561-rv5j1201	1113	18	and	and	CC
cord-022561-rv5j1201	1113	19	the	the	DT
cord-022561-rv5j1201	1113	20	hemolysis	hemolysis	NN
cord-022561-rv5j1201	1113	21	is	be	VBZ
cord-022561-rv5j1201	1113	22	extravascular	extravascular	NNP
cord-022561-rv5j1201	1113	23	(	(	-LRB-
cord-022561-rv5j1201	1113	24	i.e.	i.e.	FW
cord-022561-rv5j1201	1113	25	,	,	,
cord-022561-rv5j1201	1113	26	erythrocytes	erythrocyte	NNS
cord-022561-rv5j1201	1113	27	with	with	IN
cord-022561-rv5j1201	1113	28	surface	surface	NN
cord-022561-rv5j1201	1113	29	-	-	HYPH
cord-022561-rv5j1201	1113	30	bound	bind	VBN
cord-022561-rv5j1201	1113	31	antibody	antibody	NN
cord-022561-rv5j1201	1113	32	are	be	VBP
cord-022561-rv5j1201	1113	33	phagocytized	phagocytize	VBN
cord-022561-rv5j1201	1113	34	by	by	IN
cord-022561-rv5j1201	1113	35	macrophages	macrophage	NNS
cord-022561-rv5j1201	1113	36	,	,	,
cord-022561-rv5j1201	1113	37	mainly	mainly	RB
cord-022561-rv5j1201	1113	38	in	in	IN
cord-022561-rv5j1201	1113	39	the	the	DT
cord-022561-rv5j1201	1113	40	spleen	spleen	NN
cord-022561-rv5j1201	1113	41	)	)	-RRB-
cord-022561-rv5j1201	1113	42	.	.	.
cord-022561-rv5j1201	1114	1	IgM	IgM	NNP
cord-022561-rv5j1201	1114	2	and/or	and/or	CC
cord-022561-rv5j1201	1114	3	complement	complement	NN
cord-022561-rv5j1201	1114	4	proteins	protein	NNS
cord-022561-rv5j1201	1114	5	may	may	MD
cord-022561-rv5j1201	1114	6	also	also	RB
cord-022561-rv5j1201	1114	7	contribute	contribute	VB
cord-022561-rv5j1201	1114	8	to	to	IN
cord-022561-rv5j1201	1114	9	idiopathic	idiopathic	JJ
cord-022561-rv5j1201	1114	10	immune	immune	NN
cord-022561-rv5j1201	1114	11	-	-	HYPH
cord-022561-rv5j1201	1114	12	mediated	mediate	VBN
cord-022561-rv5j1201	1114	13	hemolytic	hemolytic	JJ
cord-022561-rv5j1201	1114	14	anemia	anemia	NN
cord-022561-rv5j1201	1114	15	.	.	.
cord-022561-rv5j1201	1115	1	Complement	complement	NN
cord-022561-rv5j1201	1115	2	factor	factor	NN
cord-022561-rv5j1201	1116	1	C3b	C3b	NNP
cord-022561-rv5j1201	1116	2	usually	usually	RB
cord-022561-rv5j1201	1116	3	acts	act	VBZ
cord-022561-rv5j1201	1116	4	as	as	IN
cord-022561-rv5j1201	1116	5	an	an	DT
cord-022561-rv5j1201	1116	6	opsonin	opsonin	NNS
cord-022561-rv5j1201	1116	7	that	that	WDT
cord-022561-rv5j1201	1116	8	promotes	promote	VBZ
cord-022561-rv5j1201	1116	9	phagocytosis	phagocytosis	NN
cord-022561-rv5j1201	1116	10	and	and	CC
cord-022561-rv5j1201	1116	11	extravascular	extravascular	JJ
cord-022561-rv5j1201	1116	12	hemolysis	hemolysis	NN
cord-022561-rv5j1201	1116	13	.	.	.
cord-022561-rv5j1201	1117	1	However	however	RB
cord-022561-rv5j1201	1117	2	,	,	,
cord-022561-rv5j1201	1117	3	formation	formation	NN
cord-022561-rv5j1201	1117	4	of	of	IN
cord-022561-rv5j1201	1117	5	the	the	DT
cord-022561-rv5j1201	1117	6	complement	complement	JJ
cord-022561-rv5j1201	1117	7	membrane	membrane	NN
cord-022561-rv5j1201	1117	8	attack	attack	NN
cord-022561-rv5j1201	1117	9	complex	complex	NN
cord-022561-rv5j1201	1117	10	on	on	IN
cord-022561-rv5j1201	1117	11	red	red	JJ
cord-022561-rv5j1201	1117	12	blood	blood	NN
cord-022561-rv5j1201	1117	13	cell	cell	NN
cord-022561-rv5j1201	1117	14	surfaces	surface	NNS
cord-022561-rv5j1201	1117	15	causes	cause	VBZ
cord-022561-rv5j1201	1117	16	intravascular	intravascular	JJ
cord-022561-rv5j1201	1117	17	hemolysis	hemolysis	NN
cord-022561-rv5j1201	1117	18	;	;	:
cord-022561-rv5j1201	1117	19	this	this	DT
cord-022561-rv5j1201	1117	20	mechanism	mechanism	NN
cord-022561-rv5j1201	1117	21	more	more	RBR
cord-022561-rv5j1201	1117	22	commonly	commonly	RB
cord-022561-rv5j1201	1117	23	occurs	occur	VBZ
cord-022561-rv5j1201	1117	24	with	with	IN
cord-022561-rv5j1201	1117	25	IgM	IgM	NNP
cord-022561-rv5j1201	1117	26	autoantibodies	autoantibody	NNS
cord-022561-rv5j1201	1117	27	.	.	.
cord-022561-rv5j1201	1118	1	Most	Most	JJS
cord-022561-rv5j1201	1118	2	immunoglobulins	immunoglobulin	NNS
cord-022561-rv5j1201	1118	3	implicated	implicate	VBN
cord-022561-rv5j1201	1118	4	in	in	IN
cord-022561-rv5j1201	1118	5	immune	immune	NN
cord-022561-rv5j1201	1118	6	-	-	HYPH
cord-022561-rv5j1201	1118	7	mediated	mediate	VBN
cord-022561-rv5j1201	1118	8	hemolytic	hemolytic	JJ
cord-022561-rv5j1201	1118	9	anemia	anemia	NN
cord-022561-rv5j1201	1118	10	are	be	VBP
cord-022561-rv5j1201	1118	11	reactive	reactive	JJ
cord-022561-rv5j1201	1118	12	at	at	IN
cord-022561-rv5j1201	1118	13	body	body	NN
cord-022561-rv5j1201	1118	14	temperature	temperature	NN
cord-022561-rv5j1201	1118	15	(	(	-LRB-
cord-022561-rv5j1201	1118	16	warm	warm	JJ
cord-022561-rv5j1201	1118	17	hemagglutinins	hemagglutinin	NNS
cord-022561-rv5j1201	1118	18	)	)	-RRB-
cord-022561-rv5j1201	1118	19	.	.	.
cord-022561-rv5j1201	1119	1	A	a	DT
cord-022561-rv5j1201	1119	2	smaller	small	JJR
cord-022561-rv5j1201	1119	3	portion	portion	NN
cord-022561-rv5j1201	1119	4	,	,	,
cord-022561-rv5j1201	1119	5	usually	usually	RB
cord-022561-rv5j1201	1119	6	IgM	IgM	NNP
cord-022561-rv5j1201	1119	7	,	,	,
cord-022561-rv5j1201	1119	8	are	be	VBP
cord-022561-rv5j1201	1119	9	more	more	RBR
cord-022561-rv5j1201	1119	10	reactive	reactive	JJ
cord-022561-rv5j1201	1119	11	at	at	IN
cord-022561-rv5j1201	1119	12	lower	low	JJR
cord-022561-rv5j1201	1119	13	temperatures	temperature	NNS
cord-022561-rv5j1201	1119	14	,	,	,
cord-022561-rv5j1201	1119	15	young	young	JJ
cord-022561-rv5j1201	1119	16	(	(	-LRB-
cord-022561-rv5j1201	1119	17	hours	hour	NNS
cord-022561-rv5j1201	1119	18	to	to	IN
cord-022561-rv5j1201	1119	19	days	day	NNS
cord-022561-rv5j1201	1119	20	old	old	JJ
cord-022561-rv5j1201	1119	21	)	)	-RRB-
cord-022561-rv5j1201	1119	22	with	with	IN
cord-022561-rv5j1201	1119	23	typical	typical	JJ
cord-022561-rv5j1201	1119	24	gross	gross	JJ
cord-022561-rv5j1201	1119	25	and	and	CC
cord-022561-rv5j1201	1119	26	microscopic	microscopic	JJ
cord-022561-rv5j1201	1119	27	changes	change	NNS
cord-022561-rv5j1201	1119	28	of	of	IN
cord-022561-rv5j1201	1119	29	immune	immune	NN
cord-022561-rv5j1201	1119	30	-	-	HYPH
cord-022561-rv5j1201	1119	31	mediated	mediate	VBN
cord-022561-rv5j1201	1119	32	hemolytic	hemolytic	JJ
cord-022561-rv5j1201	1119	33	anemia	anemia	NN
cord-022561-rv5j1201	1119	34	.	.	.
cord-022561-rv5j1201	1120	1	Pure	pure	JJ
cord-022561-rv5j1201	1120	2	Red	Red	NNP
cord-022561-rv5j1201	1120	3	Cell	Cell	NNP
cord-022561-rv5j1201	1120	4	Aplasia	Aplasia	NNP
cord-022561-rv5j1201	1120	5	.	.	.
cord-022561-rv5j1201	1121	1	Pure	pure	JJ
cord-022561-rv5j1201	1121	2	red	red	JJ
cord-022561-rv5j1201	1121	3	cell	cell	NN
cord-022561-rv5j1201	1121	4	aplasia	aplasia	NNP
cord-022561-rv5j1201	1121	5	(	(	-LRB-
cord-022561-rv5j1201	1121	6	PRCA	PRCA	NNP
cord-022561-rv5j1201	1121	7	)	)	-RRB-
cord-022561-rv5j1201	1121	8	is	be	VBZ
cord-022561-rv5j1201	1121	9	a	a	DT
cord-022561-rv5j1201	1121	10	rare	rare	JJ
cord-022561-rv5j1201	1121	11	bone	bone	NN
cord-022561-rv5j1201	1121	12	marrow	marrow	NN
cord-022561-rv5j1201	1121	13	disorder	disorder	NN
cord-022561-rv5j1201	1121	14	characterized	characterize	VBN
cord-022561-rv5j1201	1121	15	by	by	IN
cord-022561-rv5j1201	1121	16	absence	absence	NN
cord-022561-rv5j1201	1121	17	of	of	IN
cord-022561-rv5j1201	1121	18	erythropoiesis	erythropoiesis	NN
cord-022561-rv5j1201	1121	19	and	and	CC
cord-022561-rv5j1201	1121	20	severe	severe	JJ
cord-022561-rv5j1201	1121	21	nonregenerative	nonregenerative	JJ
cord-022561-rv5j1201	1121	22	anemia	anemia	NN
cord-022561-rv5j1201	1121	23	.	.	.
cord-022561-rv5j1201	1122	1	Primary	primary	JJ
cord-022561-rv5j1201	1122	2	and	and	CC
cord-022561-rv5j1201	1122	3	secondary	secondary	JJ
cord-022561-rv5j1201	1122	4	forms	form	NNS
cord-022561-rv5j1201	1122	5	of	of	IN
cord-022561-rv5j1201	1122	6	pure	pure	JJ
cord-022561-rv5j1201	1122	7	red	red	JJ
cord-022561-rv5j1201	1122	8	cell	cell	NN
cord-022561-rv5j1201	1122	9	aplasia	aplasia	NNP
cord-022561-rv5j1201	1122	10	have	have	VBP
cord-022561-rv5j1201	1122	11	been	be	VBN
cord-022561-rv5j1201	1122	12	described	describe	VBN
cord-022561-rv5j1201	1122	13	in	in	IN
cord-022561-rv5j1201	1122	14	dogs	dog	NNS
cord-022561-rv5j1201	1122	15	and	and	CC
cord-022561-rv5j1201	1122	16	cats	cat	NNS
cord-022561-rv5j1201	1122	17	.	.	.
cord-022561-rv5j1201	1123	1	Primary	primary	JJ
cord-022561-rv5j1201	1123	2	pure	pure	JJ
cord-022561-rv5j1201	1123	3	red	red	JJ
cord-022561-rv5j1201	1123	4	cell	cell	NN
cord-022561-rv5j1201	1123	5	aplasia	aplasia	NNP
cord-022561-rv5j1201	1123	6	is	be	VBZ
cord-022561-rv5j1201	1123	7	apparently	apparently	RB
cord-022561-rv5j1201	1123	8	caused	cause	VBN
cord-022561-rv5j1201	1123	9	by	by	IN
cord-022561-rv5j1201	1123	10	immune	immune	NN
cord-022561-rv5j1201	1123	11	-	-	HYPH
cord-022561-rv5j1201	1123	12	mediated	mediate	VBN
cord-022561-rv5j1201	1123	13	destruction	destruction	NN
cord-022561-rv5j1201	1123	14	of	of	IN
cord-022561-rv5j1201	1123	15	early	early	JJ
cord-022561-rv5j1201	1123	16	erythroid	erythroid	JJ
cord-022561-rv5j1201	1123	17	progenitor	progenitor	NN
cord-022561-rv5j1201	1123	18	cells	cell	NNS
cord-022561-rv5j1201	1123	19	,	,	,
cord-022561-rv5j1201	1123	20	a	a	DT
cord-022561-rv5j1201	1123	21	presumption	presumption	NN
cord-022561-rv5j1201	1123	22	supported	support	VBN
cord-022561-rv5j1201	1123	23	by	by	IN
cord-022561-rv5j1201	1123	24	the	the	DT
cord-022561-rv5j1201	1123	25	response	response	NN
cord-022561-rv5j1201	1123	26	of	of	IN
cord-022561-rv5j1201	1123	27	some	some	DT
cord-022561-rv5j1201	1123	28	patients	patient	NNS
cord-022561-rv5j1201	1123	29	to	to	IN
cord-022561-rv5j1201	1123	30	immunosuppressive	immunosuppressive	JJ
cord-022561-rv5j1201	1123	31	therapy	therapy	NN
cord-022561-rv5j1201	1123	32	and	and	CC
cord-022561-rv5j1201	1123	33	by	by	IN
cord-022561-rv5j1201	1123	34	the	the	DT
cord-022561-rv5j1201	1123	35	detection	detection	NN
cord-022561-rv5j1201	1123	36	of	of	IN
cord-022561-rv5j1201	1123	37	antibodies	antibody	NNS
cord-022561-rv5j1201	1123	38	inhibiting	inhibit	VBG
cord-022561-rv5j1201	1123	39	erythroid	erythroid	JJ
cord-022561-rv5j1201	1123	40	colony	colony	NN
cord-022561-rv5j1201	1123	41	formation	formation	NN
cord-022561-rv5j1201	1123	42	in	in	IN
cord-022561-rv5j1201	1123	43	vitro	vitro	FW
cord-022561-rv5j1201	1123	44	in	in	IN
cord-022561-rv5j1201	1123	45	some	some	DT
cord-022561-rv5j1201	1123	46	dogs	dog	NNS
cord-022561-rv5j1201	1123	47	.	.	.
cord-022561-rv5j1201	1124	1	Administration	administration	NN
cord-022561-rv5j1201	1124	2	of	of	IN
cord-022561-rv5j1201	1124	3	recombinant	recombinant	JJ
cord-022561-rv5j1201	1124	4	human	human	JJ
cord-022561-rv5j1201	1124	5	erythropoietin	erythropoietin	NN
cord-022561-rv5j1201	1124	6	(	(	-LRB-
cord-022561-rv5j1201	1124	7	rhEpo	rhepo	RB
cord-022561-rv5j1201	1124	8	)	)	-RRB-
cord-022561-rv5j1201	1124	9	has	have	VBZ
cord-022561-rv5j1201	1124	10	been	be	VBN
cord-022561-rv5j1201	1124	11	identified	identify	VBN
cord-022561-rv5j1201	1124	12	as	as	IN
cord-022561-rv5j1201	1124	13	a	a	DT
cord-022561-rv5j1201	1124	14	cause	cause	NN
cord-022561-rv5j1201	1124	15	of	of	IN
cord-022561-rv5j1201	1124	16	secondary	secondary	JJ
cord-022561-rv5j1201	1124	17	pure	pure	JJ
cord-022561-rv5j1201	1124	18	red	red	JJ
cord-022561-rv5j1201	1124	19	cell	cell	NN
cord-022561-rv5j1201	1124	20	aplasia	aplasia	NNP
cord-022561-rv5j1201	1124	21	in	in	IN
cord-022561-rv5j1201	1124	22	dogs	dog	NNS
cord-022561-rv5j1201	1124	23	,	,	,
cord-022561-rv5j1201	1124	24	cats	cat	NNS
cord-022561-rv5j1201	1124	25	,	,	,
cord-022561-rv5j1201	1124	26	and	and	CC
cord-022561-rv5j1201	1124	27	horses	horse	NNS
cord-022561-rv5j1201	1124	28	,	,	,
cord-022561-rv5j1201	1124	29	presumably	presumably	RB
cord-022561-rv5j1201	1124	30	caused	cause	VBN
cord-022561-rv5j1201	1124	31	by	by	IN
cord-022561-rv5j1201	1124	32	induction	induction	NN
cord-022561-rv5j1201	1124	33	of	of	IN
cord-022561-rv5j1201	1124	34	antibodies	antibody	NNS
cord-022561-rv5j1201	1124	35	against	against	IN
cord-022561-rv5j1201	1124	36	rhEpo	rhepo	RB
cord-022561-rv5j1201	1124	37	that	that	DT
cord-022561-rv5j1201	1124	38	cross	cross	NN
cord-022561-rv5j1201	1124	39	-	-	NN
cord-022561-rv5j1201	1124	40	react	react	VB
cord-022561-rv5j1201	1124	41	with	with	IN
cord-022561-rv5j1201	1124	42	endogenous	endogenous	JJ
cord-022561-rv5j1201	1124	43	Epo	Epo	NNP
cord-022561-rv5j1201	1124	44	.	.	.
cord-022561-rv5j1201	1125	1	Experimentation	experimentation	NN
cord-022561-rv5j1201	1125	2	with	with	IN
cord-022561-rv5j1201	1125	3	the	the	DT
cord-022561-rv5j1201	1125	4	use	use	NN
cord-022561-rv5j1201	1125	5	of	of	IN
cord-022561-rv5j1201	1125	6	speciesspecific	speciesspecific	NN
cord-022561-rv5j1201	1125	7	recombinant	recombinant	JJ
cord-022561-rv5j1201	1125	8	Epo	Epo	NNP
cord-022561-rv5j1201	1125	9	has	have	VBZ
cord-022561-rv5j1201	1125	10	produced	produce	VBN
cord-022561-rv5j1201	1125	11	mixed	mixed	JJ
cord-022561-rv5j1201	1125	12	results	result	NNS
cord-022561-rv5j1201	1125	13	.	.	.
cord-022561-rv5j1201	1126	1	Dogs	dog	NNS
cord-022561-rv5j1201	1126	2	treated	treat	VBN
cord-022561-rv5j1201	1126	3	with	with	IN
cord-022561-rv5j1201	1126	4	recombinant	recombinant	JJ
cord-022561-rv5j1201	1126	5	canine	canine	NN
cord-022561-rv5j1201	1126	6	Epo	Epo	NNP
cord-022561-rv5j1201	1126	7	have	have	VBP
cord-022561-rv5j1201	1126	8	not	not	RB
cord-022561-rv5j1201	1126	9	developed	develop	VBN
cord-022561-rv5j1201	1126	10	pure	pure	JJ
cord-022561-rv5j1201	1126	11	red	red	JJ
cord-022561-rv5j1201	1126	12	cell	cell	NN
cord-022561-rv5j1201	1126	13	aplasia	aplasia	NNP
cord-022561-rv5j1201	1126	14	.	.	.
cord-022561-rv5j1201	1127	1	However	however	RB
cord-022561-rv5j1201	1127	2	,	,	,
cord-022561-rv5j1201	1127	3	in	in	IN
cord-022561-rv5j1201	1127	4	experiments	experiment	NNS
cord-022561-rv5j1201	1127	5	reported	report	VBN
cord-022561-rv5j1201	1127	6	thus	thus	RB
cord-022561-rv5j1201	1127	7	far	far	RB
cord-022561-rv5j1201	1127	8	involving	involve	VBG
cord-022561-rv5j1201	1127	9	cats	cat	NNS
cord-022561-rv5j1201	1127	10	treated	treat	VBN
cord-022561-rv5j1201	1127	11	with	with	IN
cord-022561-rv5j1201	1127	12	recombinant	recombinant	JJ
cord-022561-rv5j1201	1127	13	feline	feline	JJ
cord-022561-rv5j1201	1127	14	Epo	Epo	NNP
cord-022561-rv5j1201	1127	15	,	,	,
cord-022561-rv5j1201	1127	16	at	at	IN
cord-022561-rv5j1201	1127	17	least	least	JJS
cord-022561-rv5j1201	1127	18	some	some	DT
cord-022561-rv5j1201	1127	19	animals	animal	NNS
cord-022561-rv5j1201	1127	20	have	have	VBP
cord-022561-rv5j1201	1127	21	developed	develop	VBN
cord-022561-rv5j1201	1127	22	pure	pure	JJ
cord-022561-rv5j1201	1127	23	red	red	JJ
cord-022561-rv5j1201	1127	24	cell	cell	NN
cord-022561-rv5j1201	1127	25	aplasia	aplasia	NNP
cord-022561-rv5j1201	1127	26	.	.	.
cord-022561-rv5j1201	1128	1	Parvoviral	Parvoviral	NNP
cord-022561-rv5j1201	1128	2	infection	infection	NN
cord-022561-rv5j1201	1128	3	has	have	VBZ
cord-022561-rv5j1201	1128	4	been	be	VBN
cord-022561-rv5j1201	1128	5	suggested	suggest	VBN
cord-022561-rv5j1201	1128	6	as	as	IN
cord-022561-rv5j1201	1128	7	a	a	DT
cord-022561-rv5j1201	1128	8	possible	possible	JJ
cord-022561-rv5j1201	1128	9	cause	cause	NN
cord-022561-rv5j1201	1128	10	of	of	IN
cord-022561-rv5j1201	1128	11	secondary	secondary	JJ
cord-022561-rv5j1201	1128	12	pure	pure	JJ
cord-022561-rv5j1201	1128	13	red	red	JJ
cord-022561-rv5j1201	1128	14	cell	cell	NN
cord-022561-rv5j1201	1128	15	aplasia	aplasia	NNP
cord-022561-rv5j1201	1128	16	in	in	IN
cord-022561-rv5j1201	1128	17	dogs	dog	NNS
cord-022561-rv5j1201	1128	18	.	.	.
cord-022561-rv5j1201	1129	1	Infection	infection	NN
cord-022561-rv5j1201	1129	2	with	with	IN
cord-022561-rv5j1201	1129	3	FeLV	FeLV	NNP
cord-022561-rv5j1201	1130	1	subgroup	subgroup	NNP
cord-022561-rv5j1201	1130	2	C	C	NNP
cord-022561-rv5j1201	1130	3	causes	cause	VBZ
cord-022561-rv5j1201	1130	4	secondary	secondary	JJ
cord-022561-rv5j1201	1130	5	erythroid	erythroid	NN
cord-022561-rv5j1201	1130	6	aplasia	aplasia	NNP
cord-022561-rv5j1201	1130	7	in	in	IN
cord-022561-rv5j1201	1130	8	cats	cat	NNS
cord-022561-rv5j1201	1130	9	,	,	,
cord-022561-rv5j1201	1130	10	probably	probably	RB
cord-022561-rv5j1201	1130	11	because	because	IN
cord-022561-rv5j1201	1130	12	of	of	IN
cord-022561-rv5j1201	1130	13	infection	infection	NN
cord-022561-rv5j1201	1130	14	of	of	IN
cord-022561-rv5j1201	1130	15	early	early	JJ
cord-022561-rv5j1201	1130	16	-	-	HYPH
cord-022561-rv5j1201	1130	17	stage	stage	NN
cord-022561-rv5j1201	1130	18	erythroid	erythroid	NN
cord-022561-rv5j1201	1130	19	precursors	precursor	NNS
cord-022561-rv5j1201	1130	20	.	.	.
cord-022561-rv5j1201	1131	1	Grossly	grossly	RB
cord-022561-rv5j1201	1131	2	,	,	,
cord-022561-rv5j1201	1131	3	animals	animal	NNS
cord-022561-rv5j1201	1131	4	with	with	IN
cord-022561-rv5j1201	1131	5	pure	pure	JJ
cord-022561-rv5j1201	1131	6	red	red	JJ
cord-022561-rv5j1201	1131	7	cell	cell	NN
cord-022561-rv5j1201	1131	8	aplasia	aplasia	NNP
cord-022561-rv5j1201	1131	9	have	have	VBP
cord-022561-rv5j1201	1131	10	pale	pale	JJ
cord-022561-rv5j1201	1131	11	mucous	mucous	JJ
cord-022561-rv5j1201	1131	12	membranes	membrane	NNS
cord-022561-rv5j1201	1131	13	without	without	IN
cord-022561-rv5j1201	1131	14	indicators	indicator	NNS
cord-022561-rv5j1201	1131	15	of	of	IN
cord-022561-rv5j1201	1131	16	hemolysis	hemolysis	NN
cord-022561-rv5j1201	1131	17	(	(	-LRB-
cord-022561-rv5j1201	1131	18	e.g.	e.g.	RB
cord-022561-rv5j1201	1131	19	,	,	,
cord-022561-rv5j1201	1131	20	icterus	icterus	NN
cord-022561-rv5j1201	1131	21	)	)	-RRB-
cord-022561-rv5j1201	1131	22	.	.	.
cord-022561-rv5j1201	1132	1	Microscopic	microscopic	JJ
cord-022561-rv5j1201	1132	2	examination	examination	NN
cord-022561-rv5j1201	1132	3	of	of	IN
cord-022561-rv5j1201	1132	4	the	the	DT
cord-022561-rv5j1201	1132	5	bone	bone	NN
cord-022561-rv5j1201	1132	6	marrow	marrow	NN
cord-022561-rv5j1201	1132	7	shows	show	VBZ
cord-022561-rv5j1201	1132	8	an	an	DT
cord-022561-rv5j1201	1132	9	absence	absence	NN
cord-022561-rv5j1201	1132	10	or	or	CC
cord-022561-rv5j1201	1132	11	near	near	IN
cord-022561-rv5j1201	1132	12	absence	absence	NN
cord-022561-rv5j1201	1132	13	of	of	IN
cord-022561-rv5j1201	1132	14	erythroid	erythroid	NN
cord-022561-rv5j1201	1132	15	precursors	precursor	NNS
cord-022561-rv5j1201	1132	16	with	with	IN
cord-022561-rv5j1201	1132	17	or	or	CC
cord-022561-rv5j1201	1132	18	without	without	IN
cord-022561-rv5j1201	1132	19	lymphocytosis	lymphocytosis	NNP
cord-022561-rv5j1201	1132	20	,	,	,
cord-022561-rv5j1201	1132	21	plasmacytosis	plasmacytosis	NNP
cord-022561-rv5j1201	1132	22	,	,	,
cord-022561-rv5j1201	1132	23	and	and	CC
cord-022561-rv5j1201	1132	24	myelofibrosis	myelofibrosis	NN
cord-022561-rv5j1201	1132	25	;	;	:
cord-022561-rv5j1201	1132	26	production	production	NN
cord-022561-rv5j1201	1132	27	of	of	IN
cord-022561-rv5j1201	1132	28	other	other	JJ
cord-022561-rv5j1201	1132	29	cell	cell	NN
cord-022561-rv5j1201	1132	30	lines	line	NNS
cord-022561-rv5j1201	1132	31	(	(	-LRB-
cord-022561-rv5j1201	1132	32	e.g.	e.g.	RB
cord-022561-rv5j1201	1132	33	,	,	,
cord-022561-rv5j1201	1132	34	neutrophils	neutrophil	NNS
cord-022561-rv5j1201	1132	35	and	and	CC
cord-022561-rv5j1201	1132	36	platelets	platelet	NNS
cord-022561-rv5j1201	1132	37	)	)	-RRB-
cord-022561-rv5j1201	1132	38	is	be	VBZ
cord-022561-rv5j1201	1132	39	normal	normal	JJ
cord-022561-rv5j1201	1132	40	or	or	CC
cord-022561-rv5j1201	1132	41	hyperplastic	hyperplastic	JJ
cord-022561-rv5j1201	1132	42	.	.	.
cord-022561-rv5j1201	1133	1	Immune	immune	NN
cord-022561-rv5j1201	1133	2	-	-	HYPH
cord-022561-rv5j1201	1133	3	Mediated	mediate	VBN
cord-022561-rv5j1201	1133	4	Neutropenia	neutropenia	NN
cord-022561-rv5j1201	1133	5	.	.	.
cord-022561-rv5j1201	1134	1	Immune	immune	NN
cord-022561-rv5j1201	1134	2	-	-	HYPH
cord-022561-rv5j1201	1134	3	mediated	mediate	VBN
cord-022561-rv5j1201	1134	4	neutropenia	neutropenia	NN
cord-022561-rv5j1201	1134	5	is	be	VBZ
cord-022561-rv5j1201	1134	6	a	a	DT
cord-022561-rv5j1201	1134	7	rare	rare	JJ
cord-022561-rv5j1201	1134	8	condition	condition	NN
cord-022561-rv5j1201	1134	9	that	that	WDT
cord-022561-rv5j1201	1134	10	has	have	VBZ
cord-022561-rv5j1201	1134	11	been	be	VBN
cord-022561-rv5j1201	1134	12	reported	report	VBN
cord-022561-rv5j1201	1134	13	in	in	IN
cord-022561-rv5j1201	1134	14	horses	horse	NNS
cord-022561-rv5j1201	1134	15	,	,	,
cord-022561-rv5j1201	1134	16	dogs	dog	NNS
cord-022561-rv5j1201	1134	17	,	,	,
cord-022561-rv5j1201	1134	18	and	and	CC
cord-022561-rv5j1201	1134	19	cats	cat	NNS
cord-022561-rv5j1201	1134	20	.	.	.
cord-022561-rv5j1201	1135	1	This	this	DT
cord-022561-rv5j1201	1135	2	disease	disease	NN
cord-022561-rv5j1201	1135	3	is	be	VBZ
cord-022561-rv5j1201	1135	4	characterized	characterize	VBN
cord-022561-rv5j1201	1135	5	by	by	IN
cord-022561-rv5j1201	1135	6	severe	severe	JJ
cord-022561-rv5j1201	1135	7	neutropenia	neutropenia	NN
cord-022561-rv5j1201	1135	8	from	from	IN
cord-022561-rv5j1201	1135	9	immune	immune	NN
cord-022561-rv5j1201	1135	10	-	-	HYPH
cord-022561-rv5j1201	1135	11	mediated	mediate	VBN
cord-022561-rv5j1201	1135	12	destruction	destruction	NN
cord-022561-rv5j1201	1135	13	of	of	IN
cord-022561-rv5j1201	1135	14	neutrophils	neutrophil	NNS
cord-022561-rv5j1201	1135	15	or	or	CC
cord-022561-rv5j1201	1135	16	their	-PRON-	PRP$
cord-022561-rv5j1201	1135	17	precursors	precursor	NNS
cord-022561-rv5j1201	1135	18	.	.	.
cord-022561-rv5j1201	1136	1	The	the	DT
cord-022561-rv5j1201	1136	2	range	range	NN
cord-022561-rv5j1201	1136	3	of	of	IN
cord-022561-rv5j1201	1136	4	causes	cause	NNS
cord-022561-rv5j1201	1136	5	is	be	VBZ
cord-022561-rv5j1201	1136	6	presumably	presumably	RB
cord-022561-rv5j1201	1136	7	similar	similar	JJ
cord-022561-rv5j1201	1136	8	to	to	IN
cord-022561-rv5j1201	1136	9	that	that	DT
cord-022561-rv5j1201	1136	10	of	of	IN
cord-022561-rv5j1201	1136	11	other	other	JJ
cord-022561-rv5j1201	1136	12	immunemediated	immunemediated	JJ
cord-022561-rv5j1201	1136	13	cytopenias	cytopenia	NNS
cord-022561-rv5j1201	1136	14	(	(	-LRB-
cord-022561-rv5j1201	1136	15	e.g.	e.g.	RB
cord-022561-rv5j1201	1136	16	,	,	,
cord-022561-rv5j1201	1136	17	immune	immune	NN
cord-022561-rv5j1201	1136	18	-	-	HYPH
cord-022561-rv5j1201	1136	19	mediated	mediate	VBN
cord-022561-rv5j1201	1136	20	hemolytic	hemolytic	JJ
cord-022561-rv5j1201	1136	21	anemia	anemia	NN
cord-022561-rv5j1201	1136	22	,	,	,
cord-022561-rv5j1201	1136	23	pure	pure	JJ
cord-022561-rv5j1201	1136	24	red	red	JJ
cord-022561-rv5j1201	1136	25	cell	cell	NN
cord-022561-rv5j1201	1136	26	aplasia	aplasia	NNP
cord-022561-rv5j1201	1136	27	,	,	,
cord-022561-rv5j1201	1136	28	and	and	CC
cord-022561-rv5j1201	1136	29	immune	immune	NN
cord-022561-rv5j1201	1136	30	-	-	HYPH
cord-022561-rv5j1201	1136	31	mediated	mediate	VBN
cord-022561-rv5j1201	1136	32	thrombocytopenia	thrombocytopenia	NN
cord-022561-rv5j1201	1136	33	)	)	-RRB-
cord-022561-rv5j1201	1136	34	.	.	.
cord-022561-rv5j1201	1137	1	Affected	affected	JJ
cord-022561-rv5j1201	1137	2	animals	animal	NNS
cord-022561-rv5j1201	1137	3	may	may	MD
cord-022561-rv5j1201	1137	4	have	have	VB
cord-022561-rv5j1201	1137	5	infections	infection	NNS
cord-022561-rv5j1201	1137	6	,	,	,
cord-022561-rv5j1201	1137	7	such	such	JJ
cord-022561-rv5j1201	1137	8	as	as	IN
cord-022561-rv5j1201	1137	9	dermatitis	dermatitis	NN
cord-022561-rv5j1201	1137	10	,	,	,
cord-022561-rv5j1201	1137	11	conjunctivitis	conjunctivitis	NN
cord-022561-rv5j1201	1137	12	,	,	,
cord-022561-rv5j1201	1137	13	or	or	CC
cord-022561-rv5j1201	1137	14	vaginitis	vaginitis	NN
cord-022561-rv5j1201	1137	15	,	,	,
cord-022561-rv5j1201	1137	16	which	which	WDT
cord-022561-rv5j1201	1137	17	are	be	VBP
cord-022561-rv5j1201	1137	18	secondary	secondary	JJ
cord-022561-rv5j1201	1137	19	to	to	IN
cord-022561-rv5j1201	1137	20	marked	marked	JJ
cord-022561-rv5j1201	1137	21	neutropenia	neutropenia	NN
cord-022561-rv5j1201	1137	22	and	and	CC
cord-022561-rv5j1201	1137	23	a	a	DT
cord-022561-rv5j1201	1137	24	compromised	compromised	JJ
cord-022561-rv5j1201	1137	25	innate	innate	JJ
cord-022561-rv5j1201	1137	26	immune	immune	JJ
cord-022561-rv5j1201	1137	27	system	system	NN
cord-022561-rv5j1201	1137	28	.	.	.
cord-022561-rv5j1201	1138	1	Microscopically	microscopically	RB
cord-022561-rv5j1201	1138	2	,	,	,
cord-022561-rv5j1201	1138	3	there	there	EX
cord-022561-rv5j1201	1138	4	may	may	MD
cord-022561-rv5j1201	1138	5	be	be	VB
cord-022561-rv5j1201	1138	6	neutrophil	neutrophil	NN
cord-022561-rv5j1201	1138	7	hyperplasia	hyperplasia	NN
cord-022561-rv5j1201	1138	8	,	,	,
cord-022561-rv5j1201	1138	9	maturation	maturation	NN
cord-022561-rv5j1201	1138	10	arrest	arrest	NN
cord-022561-rv5j1201	1138	11	,	,	,
cord-022561-rv5j1201	1138	12	or	or	CC
cord-022561-rv5j1201	1138	13	aplasia	aplasia	NNP
cord-022561-rv5j1201	1138	14	in	in	IN
cord-022561-rv5j1201	1138	15	the	the	DT
cord-022561-rv5j1201	1138	16	bone	bone	NN
cord-022561-rv5j1201	1138	17	marrow	marrow	NN
cord-022561-rv5j1201	1138	18	,	,	,
cord-022561-rv5j1201	1138	19	depending	depend	VBG
cord-022561-rv5j1201	1138	20	on	on	IN
cord-022561-rv5j1201	1138	21	which	which	WDT
cord-022561-rv5j1201	1138	22	neutrophil	neutrophil	NN
cord-022561-rv5j1201	1138	23	maturation	maturation	NN
cord-022561-rv5j1201	1138	24	stage	stage	NN
cord-022561-rv5j1201	1138	25	is	be	VBZ
cord-022561-rv5j1201	1138	26	targeted	target	VBN
cord-022561-rv5j1201	1138	27	causing	cause	VBG
cord-022561-rv5j1201	1138	28	a	a	DT
cord-022561-rv5j1201	1138	29	condition	condition	NN
cord-022561-rv5j1201	1138	30	known	know	VBN
cord-022561-rv5j1201	1138	31	as	as	IN
cord-022561-rv5j1201	1138	32	cold	cold	JJ
cord-022561-rv5j1201	1138	33	hemagglutinin	hemagglutinin	NN
cord-022561-rv5j1201	1138	34	disease	disease	NN
cord-022561-rv5j1201	1138	35	.	.	.
cord-022561-rv5j1201	1139	1	This	this	DT
cord-022561-rv5j1201	1139	2	results	result	VBZ
cord-022561-rv5j1201	1139	3	in	in	IN
cord-022561-rv5j1201	1139	4	ischemic	ischemic	JJ
cord-022561-rv5j1201	1139	5	necrosis	necrosis	NN
cord-022561-rv5j1201	1139	6	at	at	IN
cord-022561-rv5j1201	1139	7	anatomic	anatomic	JJ
cord-022561-rv5j1201	1139	8	extremities	extremity	NNS
cord-022561-rv5j1201	1139	9	(	(	-LRB-
cord-022561-rv5j1201	1139	10	e.g.	e.g.	RB
cord-022561-rv5j1201	1139	11	,	,	,
cord-022561-rv5j1201	1139	12	tips	tip	NNS
cord-022561-rv5j1201	1139	13	of	of	IN
cord-022561-rv5j1201	1139	14	the	the	DT
cord-022561-rv5j1201	1139	15	ears	ear	NNS
cord-022561-rv5j1201	1139	16	)	)	-RRB-
cord-022561-rv5j1201	1139	17	,	,	,
cord-022561-rv5j1201	1139	18	where	where	WRB
cord-022561-rv5j1201	1139	19	cooling	cool	VBG
cord-022561-rv5j1201	1139	20	of	of	IN
cord-022561-rv5j1201	1139	21	the	the	DT
cord-022561-rv5j1201	1139	22	circulation	circulation	NN
cord-022561-rv5j1201	1139	23	causes	cause	VBZ
cord-022561-rv5j1201	1139	24	autoagglutination	autoagglutination	NN
cord-022561-rv5j1201	1139	25	of	of	IN
cord-022561-rv5j1201	1139	26	erythrocytes	erythrocyte	NNS
cord-022561-rv5j1201	1139	27	and	and	CC
cord-022561-rv5j1201	1139	28	occlusion	occlusion	NN
cord-022561-rv5j1201	1139	29	of	of	IN
cord-022561-rv5j1201	1139	30	the	the	DT
cord-022561-rv5j1201	1139	31	microvasculature	microvasculature	NN
cord-022561-rv5j1201	1139	32	.	.	.
cord-022561-rv5j1201	1140	1	Typically	typically	RB
cord-022561-rv5j1201	1140	2	immunemediated	immunemediate	VBN
cord-022561-rv5j1201	1140	3	hemolytic	hemolytic	JJ
cord-022561-rv5j1201	1140	4	anemia	anemia	NN
cord-022561-rv5j1201	1140	5	targets	target	VBZ
cord-022561-rv5j1201	1140	6	mature	mature	JJ
cord-022561-rv5j1201	1140	7	erythrocytes	erythrocyte	NNS
cord-022561-rv5j1201	1140	8	,	,	,
cord-022561-rv5j1201	1140	9	causing	cause	VBG
cord-022561-rv5j1201	1140	10	a	a	DT
cord-022561-rv5j1201	1140	11	marked	marked	JJ
cord-022561-rv5j1201	1140	12	regenerative	regenerative	JJ
cord-022561-rv5j1201	1140	13	response	response	NN
cord-022561-rv5j1201	1140	14	.	.	.
cord-022561-rv5j1201	1141	1	However	however	RB
cord-022561-rv5j1201	1141	2	,	,	,
cord-022561-rv5j1201	1141	3	as	as	IN
cord-022561-rv5j1201	1141	4	discussed	discuss	VBN
cord-022561-rv5j1201	1141	5	earlier	early	RBR
cord-022561-rv5j1201	1141	6	in	in	IN
cord-022561-rv5j1201	1141	7	the	the	DT
cord-022561-rv5j1201	1141	8	chapter	chapter	NN
cord-022561-rv5j1201	1141	9	,	,	,
cord-022561-rv5j1201	1141	10	immune	immune	NN
cord-022561-rv5j1201	1141	11	-	-	HYPH
cord-022561-rv5j1201	1141	12	mediated	mediate	VBN
cord-022561-rv5j1201	1141	13	destruction	destruction	NN
cord-022561-rv5j1201	1141	14	of	of	IN
cord-022561-rv5j1201	1141	15	immature	immature	JJ
cord-022561-rv5j1201	1141	16	erythroid	erythroid	NN
cord-022561-rv5j1201	1141	17	cells	cell	NNS
cord-022561-rv5j1201	1141	18	in	in	IN
cord-022561-rv5j1201	1141	19	the	the	DT
cord-022561-rv5j1201	1141	20	bone	bone	NN
cord-022561-rv5j1201	1141	21	marrow	marrow	NN
cord-022561-rv5j1201	1141	22	may	may	MD
cord-022561-rv5j1201	1141	23	also	also	RB
cord-022561-rv5j1201	1141	24	occur	occur	VB
cord-022561-rv5j1201	1141	25	,	,	,
cord-022561-rv5j1201	1141	26	resulting	result	VBG
cord-022561-rv5j1201	1141	27	in	in	IN
cord-022561-rv5j1201	1141	28	nonregenerative	nonregenerative	JJ
cord-022561-rv5j1201	1141	29	anemia	anemia	NN
cord-022561-rv5j1201	1141	30	.	.	.
cord-022561-rv5j1201	1142	1	Pathogenesis	pathogenesis	NN
cord-022561-rv5j1201	1142	2	of	of	IN
cord-022561-rv5j1201	1142	3	secondary	secondary	JJ
cord-022561-rv5j1201	1142	4	immune	immune	NN
cord-022561-rv5j1201	1142	5	-	-	HYPH
cord-022561-rv5j1201	1142	6	mediated	mediate	VBN
cord-022561-rv5j1201	1142	7	hemolytic	hemolytic	JJ
cord-022561-rv5j1201	1142	8	anemia	anemia	NN
cord-022561-rv5j1201	1142	9	is	be	VBZ
cord-022561-rv5j1201	1142	10	dependent	dependent	JJ
cord-022561-rv5j1201	1142	11	upon	upon	IN
cord-022561-rv5j1201	1142	12	the	the	DT
cord-022561-rv5j1201	1142	13	cause	cause	NN
cord-022561-rv5j1201	1142	14	.	.	.
cord-022561-rv5j1201	1143	1	Erythrocytic	erythrocytic	JJ
cord-022561-rv5j1201	1143	2	parasites	parasite	NNS
cord-022561-rv5j1201	1143	3	may	may	MD
cord-022561-rv5j1201	1143	4	cause	cause	VB
cord-022561-rv5j1201	1143	5	immune	immune	NN
cord-022561-rv5j1201	1143	6	-	-	HYPH
cord-022561-rv5j1201	1143	7	mediated	mediate	VBN
cord-022561-rv5j1201	1143	8	hemolysis	hemolysis	NN
cord-022561-rv5j1201	1143	9	by	by	IN
cord-022561-rv5j1201	1143	10	altering	alter	VBG
cord-022561-rv5j1201	1143	11	the	the	DT
cord-022561-rv5j1201	1143	12	red	red	JJ
cord-022561-rv5j1201	1143	13	blood	blood	NN
cord-022561-rv5j1201	1143	14	cell	cell	NN
cord-022561-rv5j1201	1143	15	surface	surface	NN
cord-022561-rv5j1201	1143	16	and	and	CC
cord-022561-rv5j1201	1143	17	exposing	expose	VBG
cord-022561-rv5j1201	1143	18	"	"	``
cord-022561-rv5j1201	1143	19	hidden	hide	VBN
cord-022561-rv5j1201	1143	20	antigens	antigen	NNS
cord-022561-rv5j1201	1143	21	"	"	''
cord-022561-rv5j1201	1143	22	that	that	WDT
cord-022561-rv5j1201	1143	23	are	be	VBP
cord-022561-rv5j1201	1143	24	not	not	RB
cord-022561-rv5j1201	1143	25	recognized	recognize	VBN
cord-022561-rv5j1201	1143	26	as	as	IN
cord-022561-rv5j1201	1143	27	selfantigens	selfantigen	NNS
cord-022561-rv5j1201	1143	28	by	by	IN
cord-022561-rv5j1201	1143	29	the	the	DT
cord-022561-rv5j1201	1143	30	host	host	NN
cord-022561-rv5j1201	1143	31	's	's	POS
cord-022561-rv5j1201	1143	32	immune	immune	JJ
cord-022561-rv5j1201	1143	33	system	system	NN
cord-022561-rv5j1201	1143	34	.	.	.
cord-022561-rv5j1201	1144	1	Alternatively	alternatively	RB
cord-022561-rv5j1201	1144	2	,	,	,
cord-022561-rv5j1201	1144	3	the	the	DT
cord-022561-rv5j1201	1144	4	immune	immune	JJ
cord-022561-rv5j1201	1144	5	attack	attack	NN
cord-022561-rv5j1201	1144	6	may	may	MD
cord-022561-rv5j1201	1144	7	be	be	VB
cord-022561-rv5j1201	1144	8	directed	direct	VBN
cord-022561-rv5j1201	1144	9	at	at	IN
cord-022561-rv5j1201	1144	10	the	the	DT
cord-022561-rv5j1201	1144	11	infectious	infectious	JJ
cord-022561-rv5j1201	1144	12	agent	agent	NN
cord-022561-rv5j1201	1144	13	,	,	,
cord-022561-rv5j1201	1144	14	but	but	CC
cord-022561-rv5j1201	1144	15	erythrocytes	erythrocyte	NNS
cord-022561-rv5j1201	1144	16	are	be	VBP
cord-022561-rv5j1201	1144	17	nonspecifically	nonspecifically	RB
cord-022561-rv5j1201	1144	18	destroyed	destroy	VBN
cord-022561-rv5j1201	1144	19	because	because	IN
cord-022561-rv5j1201	1144	20	of	of	IN
cord-022561-rv5j1201	1144	21	their	-PRON-	PRP$
cord-022561-rv5j1201	1144	22	close	close	JJ
cord-022561-rv5j1201	1144	23	proximity	proximity	NN
cord-022561-rv5j1201	1144	24	-	-	:
cord-022561-rv5j1201	1144	25	this	this	DT
cord-022561-rv5j1201	1144	26	is	be	VBZ
cord-022561-rv5j1201	1144	27	called	call	VBN
cord-022561-rv5j1201	1144	28	the	the	DT
cord-022561-rv5j1201	1144	29	innocent	innocent	JJ
cord-022561-rv5j1201	1144	30	bystander	bystander	NN
cord-022561-rv5j1201	1144	31	mechanism	mechanism	NN
cord-022561-rv5j1201	1144	32	.	.	.
cord-022561-rv5j1201	1145	1	Certain	certain	JJ
cord-022561-rv5j1201	1145	2	drugs	drug	NNS
cord-022561-rv5j1201	1145	3	,	,	,
cord-022561-rv5j1201	1145	4	such	such	JJ
cord-022561-rv5j1201	1145	5	as	as	IN
cord-022561-rv5j1201	1145	6	penicillin	penicillin	NN
cord-022561-rv5j1201	1145	7	,	,	,
cord-022561-rv5j1201	1145	8	may	may	MD
cord-022561-rv5j1201	1145	9	cause	cause	VB
cord-022561-rv5j1201	1145	10	immune	immune	NN
cord-022561-rv5j1201	1145	11	-	-	HYPH
cord-022561-rv5j1201	1145	12	mediated	mediate	VBN
cord-022561-rv5j1201	1145	13	hemolytic	hemolytic	JJ
cord-022561-rv5j1201	1145	14	anemia	anemia	NN
cord-022561-rv5j1201	1145	15	by	by	IN
cord-022561-rv5j1201	1145	16	binding	bind	VBG
cord-022561-rv5j1201	1145	17	to	to	IN
cord-022561-rv5j1201	1145	18	erythrocyte	erythrocyte	NN
cord-022561-rv5j1201	1145	19	membranes	membrane	NNS
cord-022561-rv5j1201	1145	20	and	and	CC
cord-022561-rv5j1201	1145	21	forming	form	VBG
cord-022561-rv5j1201	1145	22	drug	drug	NN
cord-022561-rv5j1201	1145	23	-	-	HYPH
cord-022561-rv5j1201	1145	24	autoantigen	autoantigen	NN
cord-022561-rv5j1201	1145	25	complexes	complex	NNS
cord-022561-rv5j1201	1145	26	that	that	WDT
cord-022561-rv5j1201	1145	27	induce	induce	VBP
cord-022561-rv5j1201	1145	28	antibody	antibody	NN
cord-022561-rv5j1201	1145	29	formation	formation	NN
cord-022561-rv5j1201	1145	30	,	,	,
cord-022561-rv5j1201	1145	31	termed	term	VBD
cord-022561-rv5j1201	1145	32	hapten	hapten	NN
cord-022561-rv5j1201	1145	33	-	-	HYPH
cord-022561-rv5j1201	1145	34	dependent	dependent	JJ
cord-022561-rv5j1201	1145	35	antibodies	antibody	NNS
cord-022561-rv5j1201	1145	36	.	.	.
cord-022561-rv5j1201	1146	1	Other	other	JJ
cord-022561-rv5j1201	1146	2	proposed	propose	VBN
cord-022561-rv5j1201	1146	3	mechanisms	mechanism	NNS
cord-022561-rv5j1201	1146	4	include	include	VBP
cord-022561-rv5j1201	1146	5	binding	bind	VBG
cord-022561-rv5j1201	1146	6	of	of	IN
cord-022561-rv5j1201	1146	7	drugantibody	drugantibody	NN
cord-022561-rv5j1201	1146	8	immune	immune	JJ
cord-022561-rv5j1201	1146	9	complexes	complex	NNS
cord-022561-rv5j1201	1146	10	to	to	IN
cord-022561-rv5j1201	1146	11	the	the	DT
cord-022561-rv5j1201	1146	12	erythrocyte	erythrocyte	NN
cord-022561-rv5j1201	1146	13	membrane	membrane	NN
cord-022561-rv5j1201	1146	14	,	,	,
cord-022561-rv5j1201	1146	15	or	or	CC
cord-022561-rv5j1201	1146	16	induction	induction	NN
cord-022561-rv5j1201	1146	17	of	of	IN
cord-022561-rv5j1201	1146	18	a	a	DT
cord-022561-rv5j1201	1146	19	true	true	JJ
cord-022561-rv5j1201	1146	20	autoantibody	autoantibody	NN
cord-022561-rv5j1201	1146	21	directed	direct	VBN
cord-022561-rv5j1201	1146	22	against	against	IN
cord-022561-rv5j1201	1146	23	an	an	DT
cord-022561-rv5j1201	1146	24	erythrocyte	erythrocyte	NN
cord-022561-rv5j1201	1146	25	antigen	antigen	NN
cord-022561-rv5j1201	1146	26	.	.	.
cord-022561-rv5j1201	1147	1	Hematologic	Hematologic	NNP
cord-022561-rv5j1201	1147	2	,	,	,
cord-022561-rv5j1201	1147	3	gross	gross	JJ
cord-022561-rv5j1201	1147	4	,	,	,
cord-022561-rv5j1201	1147	5	and	and	CC
cord-022561-rv5j1201	1147	6	histopathologic	histopathologic	JJ
cord-022561-rv5j1201	1147	7	abnormalities	abnormality	NNS
cord-022561-rv5j1201	1147	8	are	be	VBP
cord-022561-rv5j1201	1147	9	typical	typical	JJ
cord-022561-rv5j1201	1147	10	of	of	IN
cord-022561-rv5j1201	1147	11	those	those	DT
cord-022561-rv5j1201	1147	12	of	of	IN
cord-022561-rv5j1201	1147	13	hemolytic	hemolytic	JJ
cord-022561-rv5j1201	1147	14	anemia	anemia	NN
cord-022561-rv5j1201	1147	15	,	,	,
cord-022561-rv5j1201	1147	16	as	as	IN
cord-022561-rv5j1201	1147	17	presented	present	VBN
cord-022561-rv5j1201	1147	18	in	in	IN
cord-022561-rv5j1201	1147	19	the	the	DT
cord-022561-rv5j1201	1147	20	earlier	early	JJR
cord-022561-rv5j1201	1147	21	section	section	NN
cord-022561-rv5j1201	1147	22	on	on	IN
cord-022561-rv5j1201	1147	23	Bone	Bone	NNP
cord-022561-rv5j1201	1147	24	Marrow	Marrow	NNP
cord-022561-rv5j1201	1147	25	and	and	CC
cord-022561-rv5j1201	1147	26	Blood	blood	NN
cord-022561-rv5j1201	1147	27	Cells	cell	NNS
cord-022561-rv5j1201	1147	28	,	,	,
cord-022561-rv5j1201	1147	29	Dysfunction	dysfunction	NN
cord-022561-rv5j1201	1147	30	/	/	SYM
cord-022561-rv5j1201	1147	31	Responses	response	NNS
cord-022561-rv5j1201	1147	32	to	to	IN
cord-022561-rv5j1201	1147	33	Injury	injury	NN
cord-022561-rv5j1201	1147	34	,	,	,
cord-022561-rv5j1201	1147	35	Blood	blood	NN
cord-022561-rv5j1201	1147	36	Cells	cell	NNS
cord-022561-rv5j1201	1147	37	,	,	,
cord-022561-rv5j1201	1147	38	Abnormal	abnormal	JJ
cord-022561-rv5j1201	1147	39	Concentrations	concentration	NNS
cord-022561-rv5j1201	1147	40	of	of	IN
cord-022561-rv5j1201	1147	41	Blood	blood	NN
cord-022561-rv5j1201	1147	42	Cells	cell	NNS
cord-022561-rv5j1201	1147	43	,	,	,
cord-022561-rv5j1201	1147	44	Anemia	anemia	NN
cord-022561-rv5j1201	1147	45	)	)	-RRB-
cord-022561-rv5j1201	1147	46	.	.	.
cord-022561-rv5j1201	1148	1	In	in	IN
cord-022561-rv5j1201	1148	2	brief	brief	NN
cord-022561-rv5j1201	1148	3	,	,	,
cord-022561-rv5j1201	1148	4	there	there	EX
cord-022561-rv5j1201	1148	5	may	may	MD
cord-022561-rv5j1201	1148	6	be	be	VB
cord-022561-rv5j1201	1148	7	spherocytes	spherocyte	NNS
cord-022561-rv5j1201	1148	8	and	and	CC
cord-022561-rv5j1201	1148	9	autoagglutination	autoagglutination	NN
cord-022561-rv5j1201	1148	10	on	on	IN
cord-022561-rv5j1201	1148	11	blood	blood	NN
cord-022561-rv5j1201	1148	12	smear	smear	NN
cord-022561-rv5j1201	1148	13	evaluation	evaluation	NN
cord-022561-rv5j1201	1148	14	,	,	,
cord-022561-rv5j1201	1148	15	icterus	icterus	NN
cord-022561-rv5j1201	1148	16	and	and	CC
cord-022561-rv5j1201	1148	17	splenomegaly	splenomegaly	NN
cord-022561-rv5j1201	1148	18	on	on	IN
cord-022561-rv5j1201	1148	19	gross	gross	JJ
cord-022561-rv5j1201	1148	20	examination	examination	NN
cord-022561-rv5j1201	1148	21	,	,	,
cord-022561-rv5j1201	1148	22	and	and	CC
cord-022561-rv5j1201	1148	23	EMH	EMH	NNP
cord-022561-rv5j1201	1148	24	,	,	,
cord-022561-rv5j1201	1148	25	erythrophagocytic	erythrophagocytic	JJ
cord-022561-rv5j1201	1148	26	macrophages	macrophage	NNS
cord-022561-rv5j1201	1148	27	,	,	,
cord-022561-rv5j1201	1148	28	and	and	CC
cord-022561-rv5j1201	1148	29	hypoxia	hypoxia	NN
cord-022561-rv5j1201	1148	30	-	-	HYPH
cord-022561-rv5j1201	1148	31	induced	induce	VBN
cord-022561-rv5j1201	1148	32	or	or	CC
cord-022561-rv5j1201	1148	33	thromboemboli	thromboemboli	NNS
cord-022561-rv5j1201	1148	34	-	-	HYPH
cord-022561-rv5j1201	1148	35	induced	induce	VBN
cord-022561-rv5j1201	1148	36	tissue	tissue	NN
cord-022561-rv5j1201	1148	37	necrosis	necrosis	NN
cord-022561-rv5j1201	1148	38	on	on	IN
cord-022561-rv5j1201	1148	39	histopathologic	histopathologic	JJ
cord-022561-rv5j1201	1148	40	examination	examination	NN
cord-022561-rv5j1201	1148	41	.	.	.
cord-022561-rv5j1201	1149	1	Dogs	dog	NNS
cord-022561-rv5j1201	1149	2	with	with	IN
cord-022561-rv5j1201	1149	3	immune	immune	NN
cord-022561-rv5j1201	1149	4	-	-	HYPH
cord-022561-rv5j1201	1149	5	mediated	mediate	VBN
cord-022561-rv5j1201	1149	6	hemolytic	hemolytic	JJ
cord-022561-rv5j1201	1149	7	anemia	anemia	NN
cord-022561-rv5j1201	1149	8	also	also	RB
cord-022561-rv5j1201	1149	9	frequently	frequently	RB
cord-022561-rv5j1201	1149	10	develop	develop	VBP
cord-022561-rv5j1201	1149	11	an	an	DT
cord-022561-rv5j1201	1149	12	inflammatory	inflammatory	JJ
cord-022561-rv5j1201	1149	13	leukocytosis	leukocytosis	NN
cord-022561-rv5j1201	1149	14	and	and	CC
cord-022561-rv5j1201	1149	15	coagulation	coagulation	NN
cord-022561-rv5j1201	1149	16	abnormalities	abnormality	NNS
cord-022561-rv5j1201	1149	17	(	(	-LRB-
cord-022561-rv5j1201	1149	18	prolonged	prolong	VBN
cord-022561-rv5j1201	1149	19	coagulation	coagulation	NN
cord-022561-rv5j1201	1149	20	times	time	NNS
cord-022561-rv5j1201	1149	21	,	,	,
cord-022561-rv5j1201	1149	22	decreased	decrease	VBD
cord-022561-rv5j1201	1149	23	plasma	plasma	NN
cord-022561-rv5j1201	1149	24	antithrombin	antithrombin	NN
cord-022561-rv5j1201	1149	25	concentration	concentration	NN
cord-022561-rv5j1201	1149	26	,	,	,
cord-022561-rv5j1201	1149	27	increased	increase	VBN
cord-022561-rv5j1201	1149	28	plasma	plasma	NN
cord-022561-rv5j1201	1149	29	concentration	concentration	NN
cord-022561-rv5j1201	1149	30	of	of	IN
cord-022561-rv5j1201	1149	31	fibrin	fibrin	NN
cord-022561-rv5j1201	1149	32	degradation	degradation	NN
cord-022561-rv5j1201	1149	33	products	product	NNS
cord-022561-rv5j1201	1149	34	,	,	,
cord-022561-rv5j1201	1149	35	thrombocytopenia	thrombocytopenia	NN
cord-022561-rv5j1201	1149	36	,	,	,
cord-022561-rv5j1201	1149	37	and	and	CC
cord-022561-rv5j1201	1149	38	disseminated	disseminate	VBN
cord-022561-rv5j1201	1149	39	intravascular	intravascular	JJ
cord-022561-rv5j1201	1149	40	coagulation	coagulation	NN
cord-022561-rv5j1201	1149	41	)	)	-RRB-
cord-022561-rv5j1201	1149	42	.	.	.
cord-022561-rv5j1201	1150	1	Intravascular	Intravascular	NNP
cord-022561-rv5j1201	1150	2	hemolysis	hemolysis	NN
cord-022561-rv5j1201	1150	3	plays	play	VBZ
cord-022561-rv5j1201	1150	4	a	a	DT
cord-022561-rv5j1201	1150	5	relatively	relatively	RB
cord-022561-rv5j1201	1150	6	insignificant	insignificant	JJ
cord-022561-rv5j1201	1150	7	role	role	NN
cord-022561-rv5j1201	1150	8	in	in	IN
cord-022561-rv5j1201	1150	9	most	most	JJS
cord-022561-rv5j1201	1150	10	cases	case	NNS
cord-022561-rv5j1201	1150	11	of	of	IN
cord-022561-rv5j1201	1150	12	immune	immune	NN
cord-022561-rv5j1201	1150	13	-	-	HYPH
cord-022561-rv5j1201	1150	14	mediated	mediate	VBN
cord-022561-rv5j1201	1150	15	hemolytic	hemolytic	JJ
cord-022561-rv5j1201	1150	16	anemia	anemia	NN
cord-022561-rv5j1201	1150	17	,	,	,
cord-022561-rv5j1201	1150	18	but	but	CC
cord-022561-rv5j1201	1150	19	evidence	evidence	NN
cord-022561-rv5j1201	1150	20	of	of	IN
cord-022561-rv5j1201	1150	21	intravascular	intravascular	JJ
cord-022561-rv5j1201	1150	22	hemolysis	hemolysis	NN
cord-022561-rv5j1201	1150	23	(	(	-LRB-
cord-022561-rv5j1201	1150	24	e.g.	e.g.	RB
cord-022561-rv5j1201	1150	25	,	,	,
cord-022561-rv5j1201	1150	26	ghost	ghost	NN
cord-022561-rv5j1201	1150	27	cells	cell	NNS
cord-022561-rv5j1201	1150	28	,	,	,
cord-022561-rv5j1201	1150	29	red	red	JJ
cord-022561-rv5j1201	1150	30	plasma	plasma	NN
cord-022561-rv5j1201	1150	31	and	and	CC
cord-022561-rv5j1201	1150	32	urine	urine	NN
cord-022561-rv5j1201	1150	33	,	,	,
cord-022561-rv5j1201	1150	34	dark	dark	JJ
cord-022561-rv5j1201	1150	35	red	red	JJ
cord-022561-rv5j1201	1150	36	kidneys	kidney	NNS
cord-022561-rv5j1201	1150	37	)	)	-RRB-
cord-022561-rv5j1201	1150	38	is	be	VBZ
cord-022561-rv5j1201	1150	39	noted	note	VBN
cord-022561-rv5j1201	1150	40	occasionally	occasionally	RB
cord-022561-rv5j1201	1150	41	,	,	,
cord-022561-rv5j1201	1150	42	presumably	presumably	RB
cord-022561-rv5j1201	1150	43	in	in	IN
cord-022561-rv5j1201	1150	44	those	those	DT
cord-022561-rv5j1201	1150	45	cases	case	NNS
cord-022561-rv5j1201	1150	46	in	in	IN
cord-022561-rv5j1201	1150	47	which	which	WDT
cord-022561-rv5j1201	1150	48	IgM	IgM	NNP
cord-022561-rv5j1201	1150	49	and	and	CC
cord-022561-rv5j1201	1150	50	complement	complement	NN
cord-022561-rv5j1201	1150	51	are	be	VBP
cord-022561-rv5j1201	1150	52	major	major	JJ
cord-022561-rv5j1201	1150	53	mediators	mediator	NNS
cord-022561-rv5j1201	1150	54	of	of	IN
cord-022561-rv5j1201	1150	55	hemolysis	hemolysis	NN
cord-022561-rv5j1201	1150	56	.	.	.
cord-022561-rv5j1201	1151	1	Neonatal	Neonatal	NNP
cord-022561-rv5j1201	1151	2	Isoerythrolysis	Isoerythrolysis	NNP
cord-022561-rv5j1201	1151	3	.	.	.
cord-022561-rv5j1201	1152	1	Neonatal	neonatal	JJ
cord-022561-rv5j1201	1152	2	isoerythrolysis	isoerythrolysis	NN
cord-022561-rv5j1201	1152	3	(	(	-LRB-
cord-022561-rv5j1201	1152	4	NI	NI	NNP
cord-022561-rv5j1201	1152	5	)	)	-RRB-
cord-022561-rv5j1201	1152	6	is	be	VBZ
cord-022561-rv5j1201	1152	7	a	a	DT
cord-022561-rv5j1201	1152	8	form	form	NN
cord-022561-rv5j1201	1152	9	of	of	IN
cord-022561-rv5j1201	1152	10	immune	immune	NN
cord-022561-rv5j1201	1152	11	-	-	HYPH
cord-022561-rv5j1201	1152	12	mediated	mediate	VBN
cord-022561-rv5j1201	1152	13	hemolytic	hemolytic	JJ
cord-022561-rv5j1201	1152	14	anemia	anemia	NN
cord-022561-rv5j1201	1152	15	in	in	IN
cord-022561-rv5j1201	1152	16	which	which	WDT
cord-022561-rv5j1201	1152	17	colostrumderived	colostrumderive	VBD
cord-022561-rv5j1201	1152	18	maternal	maternal	JJ
cord-022561-rv5j1201	1152	19	antibodies	antibody	NNS
cord-022561-rv5j1201	1152	20	react	react	VBP
cord-022561-rv5j1201	1152	21	against	against	IN
cord-022561-rv5j1201	1152	22	the	the	DT
cord-022561-rv5j1201	1152	23	newborn	newborn	NN
cord-022561-rv5j1201	1152	24	's	's	POS
cord-022561-rv5j1201	1152	25	erythrocytes	erythrocyte	NNS
cord-022561-rv5j1201	1152	26	.	.	.
cord-022561-rv5j1201	1153	1	It	-PRON-	PRP
cord-022561-rv5j1201	1153	2	is	be	VBZ
cord-022561-rv5j1201	1153	3	common	common	JJ
cord-022561-rv5j1201	1153	4	in	in	IN
cord-022561-rv5j1201	1153	5	horses	horse	NNS
cord-022561-rv5j1201	1153	6	(	(	-LRB-
cord-022561-rv5j1201	1153	7	Fig	Fig	NNP
cord-022561-rv5j1201	1153	8	.	.	.
cord-022561-rv5j1201	1153	9	13	13	CD
cord-022561-rv5j1201	1153	10	-	-	SYM
cord-022561-rv5j1201	1153	11	30	30	CD
cord-022561-rv5j1201	1153	12	)	)	-RRB-
cord-022561-rv5j1201	1153	13	and	and	CC
cord-022561-rv5j1201	1153	14	has	have	VBZ
cord-022561-rv5j1201	1153	15	been	be	VBN
cord-022561-rv5j1201	1153	16	reported	report	VBN
cord-022561-rv5j1201	1153	17	in	in	IN
cord-022561-rv5j1201	1153	18	cattle	cattle	NNS
cord-022561-rv5j1201	1153	19	,	,	,
cord-022561-rv5j1201	1153	20	cats	cat	NNS
cord-022561-rv5j1201	1153	21	,	,	,
cord-022561-rv5j1201	1153	22	and	and	CC
cord-022561-rv5j1201	1153	23	some	some	DT
cord-022561-rv5j1201	1153	24	other	other	JJ
cord-022561-rv5j1201	1153	25	domestic	domestic	JJ
cord-022561-rv5j1201	1153	26	and	and	CC
cord-022561-rv5j1201	1153	27	wildlife	wildlife	NN
cord-022561-rv5j1201	1153	28	species	specie	NNS
cord-022561-rv5j1201	1153	29	.	.	.
cord-022561-rv5j1201	1154	1	In	in	IN
cord-022561-rv5j1201	1154	2	horses	horse	NNS
cord-022561-rv5j1201	1154	3	,	,	,
cord-022561-rv5j1201	1154	4	neonatal	neonatal	JJ
cord-022561-rv5j1201	1154	5	isoerythrolysis	isoerythrolysis	NN
cord-022561-rv5j1201	1154	6	occurs	occur	VBZ
cord-022561-rv5j1201	1154	7	as	as	IN
cord-022561-rv5j1201	1154	8	a	a	DT
cord-022561-rv5j1201	1154	9	result	result	NN
cord-022561-rv5j1201	1154	10	of	of	IN
cord-022561-rv5j1201	1154	11	immunosensitization	immunosensitization	NN
cord-022561-rv5j1201	1154	12	of	of	IN
cord-022561-rv5j1201	1154	13	the	the	DT
cord-022561-rv5j1201	1154	14	dam	dam	NN
cord-022561-rv5j1201	1154	15	from	from	IN
cord-022561-rv5j1201	1154	16	exposure	exposure	NN
cord-022561-rv5j1201	1154	17	to	to	IN
cord-022561-rv5j1201	1154	18	an	an	DT
cord-022561-rv5j1201	1154	19	incompatible	incompatible	JJ
cord-022561-rv5j1201	1154	20	blood	blood	NN
cord-022561-rv5j1201	1154	21	type	type	NN
cord-022561-rv5j1201	1154	22	inherited	inherit	VBN
cord-022561-rv5j1201	1154	23	from	from	IN
cord-022561-rv5j1201	1154	24	the	the	DT
cord-022561-rv5j1201	1154	25	stallion	stallion	NN
cord-022561-rv5j1201	1154	26	(	(	-LRB-
cord-022561-rv5j1201	1154	27	e.g.	e.g.	RB
cord-022561-rv5j1201	1154	28	,	,	,
cord-022561-rv5j1201	1154	29	transplacental	transplacental	NN
cord-022561-rv5j1201	1154	30	exposure	exposure	NN
cord-022561-rv5j1201	1154	31	to	to	IN
cord-022561-rv5j1201	1154	32	fetal	fetal	JJ
cord-022561-rv5j1201	1154	33	blood	blood	NN
cord-022561-rv5j1201	1154	34	during	during	IN
cord-022561-rv5j1201	1154	35	pregnancy	pregnancy	NN
cord-022561-rv5j1201	1154	36	or	or	CC
cord-022561-rv5j1201	1154	37	mixing	mixing	NN
cord-022561-rv5j1201	1154	38	of	of	IN
cord-022561-rv5j1201	1154	39	maternal	maternal	JJ
cord-022561-rv5j1201	1154	40	and	and	CC
cord-022561-rv5j1201	1154	41	fetal	fetal	JJ
cord-022561-rv5j1201	1154	42	blood	blood	NN
cord-022561-rv5j1201	1154	43	during	during	IN
cord-022561-rv5j1201	1154	44	parturition	parturition	NN
cord-022561-rv5j1201	1154	45	)	)	-RRB-
cord-022561-rv5j1201	1154	46	.	.	.
cord-022561-rv5j1201	1155	1	A	a	DT
cord-022561-rv5j1201	1155	2	previously	previously	RB
cord-022561-rv5j1201	1155	3	mismatched	mismatch	VBN
cord-022561-rv5j1201	1155	4	blood	blood	NN
cord-022561-rv5j1201	1155	5	transfusion	transfusion	NN
cord-022561-rv5j1201	1155	6	produces	produce	VBZ
cord-022561-rv5j1201	1155	7	the	the	DT
cord-022561-rv5j1201	1155	8	same	same	JJ
cord-022561-rv5j1201	1155	9	results	result	NNS
cord-022561-rv5j1201	1155	10	.	.	.
cord-022561-rv5j1201	1156	1	Some	some	DT
cord-022561-rv5j1201	1156	2	equine	equine	JJ
cord-022561-rv5j1201	1156	3	blood	blood	NN
cord-022561-rv5j1201	1156	4	groups	group	NNS
cord-022561-rv5j1201	1156	5	are	be	VBP
cord-022561-rv5j1201	1156	6	more	more	RBR
cord-022561-rv5j1201	1156	7	antigenic	antigenic	JJ
cord-022561-rv5j1201	1156	8	than	than	IN
cord-022561-rv5j1201	1156	9	others	other	NNS
cord-022561-rv5j1201	1156	10	;	;	:
cord-022561-rv5j1201	1156	11	in	in	IN
cord-022561-rv5j1201	1156	12	particular	particular	JJ
cord-022561-rv5j1201	1156	13	,	,	,
cord-022561-rv5j1201	1156	14	types	type	NNS
cord-022561-rv5j1201	1156	15	Aa	Aa	NNP
cord-022561-rv5j1201	1156	16	and	and	CC
cord-022561-rv5j1201	1156	17	Qa	Qa	NNP
cord-022561-rv5j1201	1156	18	are	be	VBP
cord-022561-rv5j1201	1156	19	very	very	RB
cord-022561-rv5j1201	1156	20	immunogenic	immunogenic	JJ
cord-022561-rv5j1201	1156	21	in	in	IN
cord-022561-rv5j1201	1156	22	mares	mare	NNS
cord-022561-rv5j1201	1156	23	.	.	.
cord-022561-rv5j1201	1157	1	In	in	IN
cord-022561-rv5j1201	1157	2	cattle	cattle	NNS
cord-022561-rv5j1201	1157	3	,	,	,
cord-022561-rv5j1201	1157	4	neonatal	neonatal	JJ
cord-022561-rv5j1201	1157	5	isoerythrolysis	isoerythrolysis	NN
cord-022561-rv5j1201	1157	6	has	have	VBZ
cord-022561-rv5j1201	1157	7	been	be	VBN
cord-022561-rv5j1201	1157	8	caused	cause	VBN
cord-022561-rv5j1201	1157	9	by	by	IN
cord-022561-rv5j1201	1157	10	vaccination	vaccination	NN
cord-022561-rv5j1201	1157	11	with	with	IN
cord-022561-rv5j1201	1157	12	whole	whole	JJ
cord-022561-rv5j1201	1157	13	blood	blood	NN
cord-022561-rv5j1201	1157	14	products	product	NNS
cord-022561-rv5j1201	1157	15	or	or	CC
cord-022561-rv5j1201	1157	16	products	product	NNS
cord-022561-rv5j1201	1157	17	containing	contain	VBG
cord-022561-rv5j1201	1157	18	erythrocyte	erythrocyte	NN
cord-022561-rv5j1201	1157	19	membrane	membrane	NN
cord-022561-rv5j1201	1157	20	fragments	fragment	NNS
cord-022561-rv5j1201	1157	21	.	.	.
cord-022561-rv5j1201	1158	1	Neonatal	neonatal	JJ
cord-022561-rv5j1201	1158	2	isoerythrolysis	isoerythrolysis	NN
cord-022561-rv5j1201	1158	3	has	have	VBZ
cord-022561-rv5j1201	1158	4	been	be	VBN
cord-022561-rv5j1201	1158	5	produced	produce	VBN
cord-022561-rv5j1201	1158	6	experimentally	experimentally	RB
cord-022561-rv5j1201	1158	7	in	in	IN
cord-022561-rv5j1201	1158	8	dogs	dog	NNS
cord-022561-rv5j1201	1158	9	,	,	,
cord-022561-rv5j1201	1158	10	but	but	CC
cord-022561-rv5j1201	1158	11	there	there	EX
cord-022561-rv5j1201	1158	12	are	be	VBP
cord-022561-rv5j1201	1158	13	no	no	DT
cord-022561-rv5j1201	1158	14	reports	report	NNS
cord-022561-rv5j1201	1158	15	of	of	IN
cord-022561-rv5j1201	1158	16	naturally	naturally	RB
cord-022561-rv5j1201	1158	17	occurring	occur	VBG
cord-022561-rv5j1201	1158	18	disease	disease	NN
cord-022561-rv5j1201	1158	19	.	.	.
cord-022561-rv5j1201	1159	1	In	in	IN
cord-022561-rv5j1201	1159	2	cats	cat	NNS
cord-022561-rv5j1201	1159	3	the	the	DT
cord-022561-rv5j1201	1159	4	recognized	recognize	VBN
cord-022561-rv5j1201	1159	5	form	form	NN
cord-022561-rv5j1201	1159	6	of	of	IN
cord-022561-rv5j1201	1159	7	neonatal	neonatal	JJ
cord-022561-rv5j1201	1159	8	isoerythrolysis	isoerythrolysis	NN
cord-022561-rv5j1201	1159	9	does	do	VBZ
cord-022561-rv5j1201	1159	10	not	not	RB
cord-022561-rv5j1201	1159	11	depend	depend	VB
cord-022561-rv5j1201	1159	12	on	on	IN
cord-022561-rv5j1201	1159	13	prior	prior	JJ
cord-022561-rv5j1201	1159	14	maternal	maternal	JJ
cord-022561-rv5j1201	1159	15	immunosensitization	immunosensitization	NN
cord-022561-rv5j1201	1159	16	but	but	CC
cord-022561-rv5j1201	1159	17	on	on	IN
cord-022561-rv5j1201	1159	18	naturally	naturally	RB
cord-022561-rv5j1201	1159	19	occurring	occur	VBG
cord-022561-rv5j1201	1159	20	anti	anti	JJ
cord-022561-rv5j1201	1159	21	-	-	JJ
cord-022561-rv5j1201	1159	22	A	a	JJ
cord-022561-rv5j1201	1159	23	antibodies	antibody	NNS
cord-022561-rv5j1201	1159	24	in	in	IN
cord-022561-rv5j1201	1159	25	queens	queen	NNS
cord-022561-rv5j1201	1159	26	with	with	IN
cord-022561-rv5j1201	1159	27	type	type	NN
cord-022561-rv5j1201	1159	28	B	b	NN
cord-022561-rv5j1201	1159	29	blood	blood	NN
cord-022561-rv5j1201	1159	30	.	.	.
cord-022561-rv5j1201	1160	1	Affected	affected	JJ
cord-022561-rv5j1201	1160	2	animals	animal	NNS
cord-022561-rv5j1201	1160	3	are	be	VBP
cord-022561-rv5j1201	1160	4	S	S	NNP
cord-022561-rv5j1201	1160	5	L	L	NNP
cord-022561-rv5j1201	1160	6	rather	rather	RB
cord-022561-rv5j1201	1160	7	a	a	DT
cord-022561-rv5j1201	1160	8	secondary	secondary	JJ
cord-022561-rv5j1201	1160	9	complication	complication	NN
cord-022561-rv5j1201	1160	10	of	of	IN
cord-022561-rv5j1201	1160	11	many	many	JJ
cord-022561-rv5j1201	1160	12	types	type	NNS
cord-022561-rv5j1201	1160	13	of	of	IN
cord-022561-rv5j1201	1160	14	underlying	underlie	VBG
cord-022561-rv5j1201	1160	15	disease	disease	NN
cord-022561-rv5j1201	1160	16	,	,	,
cord-022561-rv5j1201	1160	17	including	include	VBG
cord-022561-rv5j1201	1160	18	severe	severe	JJ
cord-022561-rv5j1201	1160	19	inflammation	inflammation	NN
cord-022561-rv5j1201	1160	20	,	,	,
cord-022561-rv5j1201	1160	21	organ	organ	NN
cord-022561-rv5j1201	1160	22	failure	failure	NN
cord-022561-rv5j1201	1160	23	,	,	,
cord-022561-rv5j1201	1160	24	and	and	CC
cord-022561-rv5j1201	1160	25	neoplasia	neoplasia	NN
cord-022561-rv5j1201	1160	26	.	.	.
cord-022561-rv5j1201	1161	1	It	-PRON-	PRP
cord-022561-rv5j1201	1161	2	is	be	VBZ
cord-022561-rv5j1201	1161	3	included	include	VBN
cord-022561-rv5j1201	1161	4	in	in	IN
cord-022561-rv5j1201	1161	5	the	the	DT
cord-022561-rv5j1201	1161	6	section	section	NN
cord-022561-rv5j1201	1161	7	on	on	IN
cord-022561-rv5j1201	1161	8	Inflammatory	Inflammatory	NNP
cord-022561-rv5j1201	1161	9	Disorders	Disorders	NNPS
cord-022561-rv5j1201	1161	10	because	because	IN
cord-022561-rv5j1201	1161	11	the	the	DT
cord-022561-rv5j1201	1161	12	coagulation	coagulation	NN
cord-022561-rv5j1201	1161	13	cascade	cascade	NN
cord-022561-rv5j1201	1161	14	is	be	VBZ
cord-022561-rv5j1201	1161	15	closely	closely	RB
cord-022561-rv5j1201	1161	16	linked	link	VBN
cord-022561-rv5j1201	1161	17	to	to	IN
cord-022561-rv5j1201	1161	18	inflammatory	inflammatory	JJ
cord-022561-rv5j1201	1161	19	pathways	pathway	NNS
cord-022561-rv5j1201	1161	20	.	.	.
cord-022561-rv5j1201	1162	1	Information	information	NN
cord-022561-rv5j1201	1162	2	on	on	IN
cord-022561-rv5j1201	1162	3	this	this	DT
cord-022561-rv5j1201	1162	4	topic	topic	NN
cord-022561-rv5j1201	1162	5	,	,	,
cord-022561-rv5j1201	1162	6	including	include	VBG
cord-022561-rv5j1201	1162	7	E-	E-	NNP
cord-022561-rv5j1201	1162	8	Fig	Fig	NNP
cord-022561-rv5j1201	1162	9	.	.	.
cord-022561-rv5j1201	1163	1	13	13	CD
cord-022561-rv5j1201	1163	2	-5	-5	NNP
cord-022561-rv5j1201	1163	3	,	,	,
cord-022561-rv5j1201	1163	4	is	be	VBZ
cord-022561-rv5j1201	1163	5	available	available	JJ
cord-022561-rv5j1201	1163	6	at	at	IN
cord-022561-rv5j1201	1163	7	www.expertconsult.com	www.expertconsult.com	ADD
cord-022561-rv5j1201	1163	8	.	.	.
cord-022561-rv5j1201	1164	1	as	as	RB
cord-022561-rv5j1201	1164	2	well	well	RB
cord-022561-rv5j1201	1164	3	as	as	IN
cord-022561-rv5j1201	1164	4	in	in	IN
cord-022561-rv5j1201	1164	5	Chapter	chapter	NN
cord-022561-rv5j1201	1164	6	2	2	CD
cord-022561-rv5j1201	1164	7	.	.	.
cord-022561-rv5j1201	1165	1	The	the	DT
cord-022561-rv5j1201	1165	2	term	term	NN
cord-022561-rv5j1201	1165	3	hematopoietic	hematopoietic	JJ
cord-022561-rv5j1201	1165	4	neoplasia	neoplasia	NN
cord-022561-rv5j1201	1165	5	encompasses	encompass	VBZ
cord-022561-rv5j1201	1165	6	a	a	DT
cord-022561-rv5j1201	1165	7	large	large	JJ
cord-022561-rv5j1201	1165	8	and	and	CC
cord-022561-rv5j1201	1165	9	diverse	diverse	JJ
cord-022561-rv5j1201	1165	10	group	group	NN
cord-022561-rv5j1201	1165	11	of	of	IN
cord-022561-rv5j1201	1165	12	clonal	clonal	JJ
cord-022561-rv5j1201	1165	13	proliferative	proliferative	JJ
cord-022561-rv5j1201	1165	14	disorders	disorder	NNS
cord-022561-rv5j1201	1165	15	of	of	IN
cord-022561-rv5j1201	1165	16	hematopoietic	hematopoietic	JJ
cord-022561-rv5j1201	1165	17	cells	cell	NNS
cord-022561-rv5j1201	1165	18	.	.	.
cord-022561-rv5j1201	1166	1	Historically	historically	RB
cord-022561-rv5j1201	1166	2	,	,	,
cord-022561-rv5j1201	1166	3	numerous	numerous	JJ
cord-022561-rv5j1201	1166	4	systems	system	NNS
cord-022561-rv5j1201	1166	5	have	have	VBP
cord-022561-rv5j1201	1166	6	been	be	VBN
cord-022561-rv5j1201	1166	7	used	use	VBN
cord-022561-rv5j1201	1166	8	to	to	TO
cord-022561-rv5j1201	1166	9	classify	classify	VB
cord-022561-rv5j1201	1166	10	hematopoietic	hematopoietic	JJ
cord-022561-rv5j1201	1166	11	neoplasms	neoplasm	NNS
cord-022561-rv5j1201	1166	12	in	in	IN
cord-022561-rv5j1201	1166	13	human	human	JJ
cord-022561-rv5j1201	1166	14	medicine	medicine	NN
cord-022561-rv5j1201	1166	15	,	,	,
cord-022561-rv5j1201	1166	16	some	some	DT
cord-022561-rv5j1201	1166	17	of	of	IN
cord-022561-rv5j1201	1166	18	which	which	WDT
cord-022561-rv5j1201	1166	19	have	have	VBP
cord-022561-rv5j1201	1166	20	been	be	VBN
cord-022561-rv5j1201	1166	21	applied	apply	VBN
cord-022561-rv5j1201	1166	22	inconsistently	inconsistently	RB
cord-022561-rv5j1201	1166	23	to	to	IN
cord-022561-rv5j1201	1166	24	veterinary	veterinary	JJ
cord-022561-rv5j1201	1166	25	species	specie	NNS
cord-022561-rv5j1201	1166	26	(	(	-LRB-
cord-022561-rv5j1201	1166	27	examples	example	NNS
cord-022561-rv5j1201	1166	28	include	include	VBP
cord-022561-rv5j1201	1166	29	the	the	DT
cord-022561-rv5j1201	1166	30	Kiel	Kiel	NNP
cord-022561-rv5j1201	1166	31	classification	classification	NN
cord-022561-rv5j1201	1166	32	and	and	CC
cord-022561-rv5j1201	1166	33	National	National	NNP
cord-022561-rv5j1201	1166	34	Cancer	Cancer	NNP
cord-022561-rv5j1201	1166	35	Institute	Institute	NNP
cord-022561-rv5j1201	1166	36	Working	Working	NNP
cord-022561-rv5j1201	1166	37	Formulation	Formulation	NNP
cord-022561-rv5j1201	1166	38	)	)	-RRB-
cord-022561-rv5j1201	1166	39	.	.	.
cord-022561-rv5j1201	1167	1	The	the	DT
cord-022561-rv5j1201	1167	2	World	World	NNP
cord-022561-rv5j1201	1167	3	Health	Health	NNP
cord-022561-rv5j1201	1167	4	Organization	Organization	NNP
cord-022561-rv5j1201	1167	5	(	(	-LRB-
cord-022561-rv5j1201	1167	6	WHO	who	WP
cord-022561-rv5j1201	1167	7	)	)	-RRB-
cord-022561-rv5j1201	1167	8	classification	classification	NN
cord-022561-rv5j1201	1167	9	of	of	IN
cord-022561-rv5j1201	1167	10	hematopoietic	hematopoietic	JJ
cord-022561-rv5j1201	1167	11	neoplasia	neoplasia	NN
cord-022561-rv5j1201	1167	12	was	be	VBD
cord-022561-rv5j1201	1167	13	first	first	RB
cord-022561-rv5j1201	1167	14	published	publish	VBN
cord-022561-rv5j1201	1167	15	in	in	IN
cord-022561-rv5j1201	1167	16	2001	2001	CD
cord-022561-rv5j1201	1167	17	(	(	-LRB-
cord-022561-rv5j1201	1167	18	updated	update	VBN
cord-022561-rv5j1201	1167	19	in	in	IN
cord-022561-rv5j1201	1167	20	2008	2008	CD
cord-022561-rv5j1201	1167	21	)	)	-RRB-
cord-022561-rv5j1201	1167	22	and	and	CC
cord-022561-rv5j1201	1167	23	is	be	VBZ
cord-022561-rv5j1201	1167	24	based	base	VBN
cord-022561-rv5j1201	1167	25	on	on	IN
cord-022561-rv5j1201	1167	26	the	the	DT
cord-022561-rv5j1201	1167	27	principles	principle	NNS
cord-022561-rv5j1201	1167	28	defined	define	VBN
cord-022561-rv5j1201	1167	29	in	in	IN
cord-022561-rv5j1201	1167	30	the	the	DT
cord-022561-rv5j1201	1167	31	Revised	revise	VBN
cord-022561-rv5j1201	1167	32	European	european	JJ
cord-022561-rv5j1201	1167	33	-	-	HYPH
cord-022561-rv5j1201	1167	34	American	american	JJ
cord-022561-rv5j1201	1167	35	Classification	Classification	NNP
cord-022561-rv5j1201	1167	36	of	of	IN
cord-022561-rv5j1201	1167	37	Lymphoid	Lymphoid	NNP
cord-022561-rv5j1201	1167	38	Neoplasms	Neoplasms	NNP
cord-022561-rv5j1201	1167	39	(	(	-LRB-
cord-022561-rv5j1201	1167	40	REAL	REAL	NNP
cord-022561-rv5j1201	1167	41	)	)	-RRB-
cord-022561-rv5j1201	1167	42	from	from	IN
cord-022561-rv5j1201	1167	43	the	the	DT
cord-022561-rv5j1201	1167	44	International	International	NNP
cord-022561-rv5j1201	1167	45	Lymphoma	Lymphoma	NNP
cord-022561-rv5j1201	1167	46	Study	Study	NNP
cord-022561-rv5j1201	1167	47	Group	Group	NNP
cord-022561-rv5j1201	1167	48	.	.	.
cord-022561-rv5j1201	1168	1	The	the	DT
cord-022561-rv5j1201	1168	2	WHO	who	WP
cord-022561-rv5j1201	1168	3	classification	classification	NN
cord-022561-rv5j1201	1168	4	system	system	NN
cord-022561-rv5j1201	1168	5	is	be	VBZ
cord-022561-rv5j1201	1168	6	considered	consider	VBN
cord-022561-rv5j1201	1168	7	the	the	DT
cord-022561-rv5j1201	1168	8	first	first	JJ
cord-022561-rv5j1201	1168	9	true	true	JJ
cord-022561-rv5j1201	1168	10	worldwide	worldwide	JJ
cord-022561-rv5j1201	1168	11	consensus	consensus	NN
cord-022561-rv5j1201	1168	12	on	on	IN
cord-022561-rv5j1201	1168	13	the	the	DT
cord-022561-rv5j1201	1168	14	classification	classification	NN
cord-022561-rv5j1201	1168	15	of	of	IN
cord-022561-rv5j1201	1168	16	hematopoietic	hematopoietic	JJ
cord-022561-rv5j1201	1168	17	malignancies	malignancy	NNS
cord-022561-rv5j1201	1168	18	and	and	CC
cord-022561-rv5j1201	1168	19	integrates	integrate	VBZ
cord-022561-rv5j1201	1168	20	information	information	NN
cord-022561-rv5j1201	1168	21	on	on	IN
cord-022561-rv5j1201	1168	22	tumor	tumor	NN
cord-022561-rv5j1201	1168	23	topography	topography	NN
cord-022561-rv5j1201	1168	24	,	,	,
cord-022561-rv5j1201	1168	25	cell	cell	NN
cord-022561-rv5j1201	1168	26	morphology	morphology	NN
cord-022561-rv5j1201	1168	27	,	,	,
cord-022561-rv5j1201	1168	28	immunophenotype	immunophenotype	NN
cord-022561-rv5j1201	1168	29	,	,	,
cord-022561-rv5j1201	1168	30	genetic	genetic	JJ
cord-022561-rv5j1201	1168	31	features	feature	NNS
cord-022561-rv5j1201	1168	32	,	,	,
cord-022561-rv5j1201	1168	33	and	and	CC
cord-022561-rv5j1201	1168	34	clinical	clinical	JJ
cord-022561-rv5j1201	1168	35	presentation	presentation	NN
cord-022561-rv5j1201	1168	36	and	and	CC
cord-022561-rv5j1201	1168	37	course	course	NN
cord-022561-rv5j1201	1168	38	.	.	.
cord-022561-rv5j1201	1169	1	A	a	DT
cord-022561-rv5j1201	1169	2	veterinary	veterinary	JJ
cord-022561-rv5j1201	1169	3	reference	reference	NN
cord-022561-rv5j1201	1169	4	of	of	IN
cord-022561-rv5j1201	1169	5	the	the	DT
cord-022561-rv5j1201	1169	6	WHO	who	WP
cord-022561-rv5j1201	1169	7	classification	classification	NN
cord-022561-rv5j1201	1169	8	system	system	NN
cord-022561-rv5j1201	1169	9	,	,	,
cord-022561-rv5j1201	1169	10	published	publish	VBN
cord-022561-rv5j1201	1169	11	in	in	IN
cord-022561-rv5j1201	1169	12	2002	2002	CD
cord-022561-rv5j1201	1169	13	,	,	,
cord-022561-rv5j1201	1169	14	was	be	VBD
cord-022561-rv5j1201	1169	15	later	later	RB
cord-022561-rv5j1201	1169	16	validated	validate	VBN
cord-022561-rv5j1201	1169	17	in	in	IN
cord-022561-rv5j1201	1169	18	2011	2011	CD
cord-022561-rv5j1201	1169	19	using	use	VBG
cord-022561-rv5j1201	1169	20	the	the	DT
cord-022561-rv5j1201	1169	21	canine	canine	JJ
cord-022561-rv5j1201	1169	22	model	model	NN
cord-022561-rv5j1201	1169	23	of	of	IN
cord-022561-rv5j1201	1169	24	lymphoma	lymphoma	NN
cord-022561-rv5j1201	1169	25	.	.	.
cord-022561-rv5j1201	1170	1	This	this	DT
cord-022561-rv5j1201	1170	2	project	project	NN
cord-022561-rv5j1201	1170	3	,	,	,
cord-022561-rv5j1201	1170	4	modeled	model	VBN
cord-022561-rv5j1201	1170	5	after	after	IN
cord-022561-rv5j1201	1170	6	the	the	DT
cord-022561-rv5j1201	1170	7	study	study	NN
cord-022561-rv5j1201	1170	8	to	to	TO
cord-022561-rv5j1201	1170	9	validate	validate	VB
cord-022561-rv5j1201	1170	10	the	the	DT
cord-022561-rv5j1201	1170	11	system	system	NN
cord-022561-rv5j1201	1170	12	in	in	IN
cord-022561-rv5j1201	1170	13	human	human	JJ
cord-022561-rv5j1201	1170	14	beings	being	NNS
cord-022561-rv5j1201	1170	15	,	,	,
cord-022561-rv5j1201	1170	16	yielded	yield	VBD
cord-022561-rv5j1201	1170	17	an	an	DT
cord-022561-rv5j1201	1170	18	overall	overall	JJ
cord-022561-rv5j1201	1170	19	accuracy	accuracy	NN
cord-022561-rv5j1201	1170	20	(	(	-LRB-
cord-022561-rv5j1201	1170	21	i.e.	i.e.	FW
cord-022561-rv5j1201	1170	22	,	,	,
cord-022561-rv5j1201	1170	23	agreement	agreement	NN
cord-022561-rv5j1201	1170	24	on	on	IN
cord-022561-rv5j1201	1170	25	a	a	DT
cord-022561-rv5j1201	1170	26	diagnosis	diagnosis	NN
cord-022561-rv5j1201	1170	27	)	)	-RRB-
cord-022561-rv5j1201	1170	28	among	among	IN
cord-022561-rv5j1201	1170	29	pathologists	pathologist	NNS
cord-022561-rv5j1201	1170	30	of	of	IN
cord-022561-rv5j1201	1170	31	83	83	CD
cord-022561-rv5j1201	1170	32	%	%	NN
cord-022561-rv5j1201	1170	33	.	.	.
cord-022561-rv5j1201	1171	1	Currently	currently	RB
cord-022561-rv5j1201	1171	2	this	this	DT
cord-022561-rv5j1201	1171	3	classification	classification	NN
cord-022561-rv5j1201	1171	4	system	system	NN
cord-022561-rv5j1201	1171	5	is	be	VBZ
cord-022561-rv5j1201	1171	6	accepted	accept	VBN
cord-022561-rv5j1201	1171	7	as	as	IN
cord-022561-rv5j1201	1171	8	the	the	DT
cord-022561-rv5j1201	1171	9	method	method	NN
cord-022561-rv5j1201	1171	10	of	of	IN
cord-022561-rv5j1201	1171	11	choice	choice	NN
cord-022561-rv5j1201	1171	12	in	in	IN
cord-022561-rv5j1201	1171	13	both	both	CC
cord-022561-rv5j1201	1171	14	human	human	JJ
cord-022561-rv5j1201	1171	15	and	and	CC
cord-022561-rv5j1201	1171	16	veterinary	veterinary	JJ
cord-022561-rv5j1201	1171	17	medicine	medicine	NN
cord-022561-rv5j1201	1171	18	.	.	.
cord-022561-rv5j1201	1172	1	The	the	DT
cord-022561-rv5j1201	1172	2	WHO	who	WP
cord-022561-rv5j1201	1172	3	classification	classification	NN
cord-022561-rv5j1201	1172	4	broadly	broadly	RB
cord-022561-rv5j1201	1172	5	categorizes	categorize	VBZ
cord-022561-rv5j1201	1172	6	neoplasms	neoplasm	NNS
cord-022561-rv5j1201	1172	7	primarily	primarily	RB
cord-022561-rv5j1201	1172	8	according	accord	VBG
cord-022561-rv5j1201	1172	9	to	to	IN
cord-022561-rv5j1201	1172	10	cell	cell	NN
cord-022561-rv5j1201	1172	11	lineage	lineage	NN
cord-022561-rv5j1201	1172	12	:	:	:
cord-022561-rv5j1201	1172	13	myeloid	myeloid	JJ
cord-022561-rv5j1201	1172	14	,	,	,
cord-022561-rv5j1201	1172	15	lymphoid	lymphoid	NN
cord-022561-rv5j1201	1172	16	,	,	,
cord-022561-rv5j1201	1172	17	and	and	CC
cord-022561-rv5j1201	1172	18	histiocytic	histiocytic	NNP
cord-022561-rv5j1201	1172	19	.	.	.
cord-022561-rv5j1201	1173	1	This	this	DT
cord-022561-rv5j1201	1173	2	distinction	distinction	NN
cord-022561-rv5j1201	1173	3	is	be	VBZ
cord-022561-rv5j1201	1173	4	based	base	VBN
cord-022561-rv5j1201	1173	5	on	on	IN
cord-022561-rv5j1201	1173	6	the	the	DT
cord-022561-rv5j1201	1173	7	fact	fact	NN
cord-022561-rv5j1201	1173	8	that	that	IN
cord-022561-rv5j1201	1173	9	the	the	DT
cord-022561-rv5j1201	1173	10	earliest	early	JJS
cord-022561-rv5j1201	1173	11	commitment	commitment	NN
cord-022561-rv5j1201	1173	12	of	of	IN
cord-022561-rv5j1201	1173	13	a	a	DT
cord-022561-rv5j1201	1173	14	pluripotent	pluripotent	JJ
cord-022561-rv5j1201	1173	15	HSC	HSC	NNP
cord-022561-rv5j1201	1173	16	is	be	VBZ
cord-022561-rv5j1201	1173	17	to	to	IN
cord-022561-rv5j1201	1173	18	either	either	CC
cord-022561-rv5j1201	1173	19	a	a	DT
cord-022561-rv5j1201	1173	20	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	1173	21	or	or	CC
cord-022561-rv5j1201	1173	22	nonlymphoid	nonlymphoid	JJ
cord-022561-rv5j1201	1173	23	lineage	lineage	NN
cord-022561-rv5j1201	1173	24	.	.	.
cord-022561-rv5j1201	1174	1	Many	many	JJ
cord-022561-rv5j1201	1174	2	pathologists	pathologist	NNS
cord-022561-rv5j1201	1174	3	and	and	CC
cord-022561-rv5j1201	1174	4	clinicians	clinician	NNS
cord-022561-rv5j1201	1174	5	distinguish	distinguish	VBP
cord-022561-rv5j1201	1174	6	leukemias	leukemias	RB
cord-022561-rv5j1201	1174	7	from	from	IN
cord-022561-rv5j1201	1174	8	other	other	JJ
cord-022561-rv5j1201	1174	9	hematopoietic	hematopoietic	JJ
cord-022561-rv5j1201	1174	10	neoplasms	neoplasm	NNS
cord-022561-rv5j1201	1174	11	.	.	.
cord-022561-rv5j1201	1175	1	Leukemia	leukemia	NN
cord-022561-rv5j1201	1175	2	refers	refer	VBZ
cord-022561-rv5j1201	1175	3	to	to	IN
cord-022561-rv5j1201	1175	4	a	a	DT
cord-022561-rv5j1201	1175	5	group	group	NN
cord-022561-rv5j1201	1175	6	of	of	IN
cord-022561-rv5j1201	1175	7	hematopoietic	hematopoietic	JJ
cord-022561-rv5j1201	1175	8	neoplasms	neoplasm	NNS
cord-022561-rv5j1201	1175	9	that	that	WDT
cord-022561-rv5j1201	1175	10	arise	arise	VBP
cord-022561-rv5j1201	1175	11	from	from	IN
cord-022561-rv5j1201	1175	12	the	the	DT
cord-022561-rv5j1201	1175	13	bone	bone	NN
cord-022561-rv5j1201	1175	14	marrow	marrow	NN
cord-022561-rv5j1201	1175	15	and	and	CC
cord-022561-rv5j1201	1175	16	are	be	VBP
cord-022561-rv5j1201	1175	17	present	present	JJ
cord-022561-rv5j1201	1175	18	within	within	IN
cord-022561-rv5j1201	1175	19	the	the	DT
cord-022561-rv5j1201	1175	20	blood	blood	NN
cord-022561-rv5j1201	1175	21	.	.	.
cord-022561-rv5j1201	1176	1	Leukemia	leukemia	NN
cord-022561-rv5j1201	1176	2	may	may	MD
cord-022561-rv5j1201	1176	3	be	be	VB
cord-022561-rv5j1201	1176	4	difficult	difficult	JJ
cord-022561-rv5j1201	1176	5	to	to	TO
cord-022561-rv5j1201	1176	6	differentiate	differentiate	VB
cord-022561-rv5j1201	1176	7	from	from	IN
cord-022561-rv5j1201	1176	8	other	other	JJ
cord-022561-rv5j1201	1176	9	forms	form	NNS
cord-022561-rv5j1201	1176	10	of	of	IN
cord-022561-rv5j1201	1176	11	hematopoietic	hematopoietic	JJ
cord-022561-rv5j1201	1176	12	neoplasms	neoplasm	NNS
cord-022561-rv5j1201	1176	13	that	that	WDT
cord-022561-rv5j1201	1176	14	originate	originate	VBP
cord-022561-rv5j1201	1176	15	outside	outside	IN
cord-022561-rv5j1201	1176	16	of	of	IN
cord-022561-rv5j1201	1176	17	the	the	DT
cord-022561-rv5j1201	1176	18	bone	bone	NN
cord-022561-rv5j1201	1176	19	marrow	marrow	NN
cord-022561-rv5j1201	1176	20	but	but	CC
cord-022561-rv5j1201	1176	21	infiltrate	infiltrate	VB
cord-022561-rv5j1201	1176	22	the	the	DT
cord-022561-rv5j1201	1176	23	bone	bone	NN
cord-022561-rv5j1201	1176	24	marrow	marrow	NN
cord-022561-rv5j1201	1176	25	and	and	CC
cord-022561-rv5j1201	1176	26	blood	blood	NN
cord-022561-rv5j1201	1176	27	.	.	.
cord-022561-rv5j1201	1177	1	For	for	IN
cord-022561-rv5j1201	1177	2	simplicity	simplicity	NN
cord-022561-rv5j1201	1177	3	,	,	,
cord-022561-rv5j1201	1177	4	cases	case	NNS
cord-022561-rv5j1201	1177	5	of	of	IN
cord-022561-rv5j1201	1177	6	secondary	secondary	JJ
cord-022561-rv5j1201	1177	7	bone	bone	NN
cord-022561-rv5j1201	1177	8	marrow	marrow	NN
cord-022561-rv5j1201	1177	9	or	or	CC
cord-022561-rv5j1201	1177	10	blood	blood	NN
cord-022561-rv5j1201	1177	11	involvement	involvement	NN
cord-022561-rv5j1201	1177	12	may	may	MD
cord-022561-rv5j1201	1177	13	not	not	RB
cord-022561-rv5j1201	1177	14	be	be	VB
cord-022561-rv5j1201	1177	15	considered	consider	VBN
cord-022561-rv5j1201	1177	16	leukemia	leukemia	NN
cord-022561-rv5j1201	1177	17	but	but	CC
cord-022561-rv5j1201	1177	18	rather	rather	RB
cord-022561-rv5j1201	1177	19	the	the	DT
cord-022561-rv5j1201	1177	20	"	"	``
cord-022561-rv5j1201	1177	21	leukemic	leukemic	JJ
cord-022561-rv5j1201	1177	22	phase	phase	NN
cord-022561-rv5j1201	1177	23	"	"	''
cord-022561-rv5j1201	1177	24	of	of	IN
cord-022561-rv5j1201	1177	25	another	another	DT
cord-022561-rv5j1201	1177	26	primary	primary	JJ
cord-022561-rv5j1201	1177	27	neoplasm	neoplasm	NN
cord-022561-rv5j1201	1177	28	.	.	.
cord-022561-rv5j1201	1178	1	It	-PRON-	PRP
cord-022561-rv5j1201	1178	2	is	be	VBZ
cord-022561-rv5j1201	1178	3	now	now	RB
cord-022561-rv5j1201	1178	4	recognized	recognize	VBN
cord-022561-rv5j1201	1178	5	that	that	IN
cord-022561-rv5j1201	1178	6	certain	certain	JJ
cord-022561-rv5j1201	1178	7	lymphomas	lymphoma	NNS
cord-022561-rv5j1201	1178	8	and	and	CC
cord-022561-rv5j1201	1178	9	leukemias	leukemia	NNS
cord-022561-rv5j1201	1178	10	are	be	VBP
cord-022561-rv5j1201	1178	11	different	different	JJ
cord-022561-rv5j1201	1178	12	manifestations	manifestation	NNS
cord-022561-rv5j1201	1178	13	of	of	IN
cord-022561-rv5j1201	1178	14	the	the	DT
cord-022561-rv5j1201	1178	15	same	same	JJ
cord-022561-rv5j1201	1178	16	disease	disease	NN
cord-022561-rv5j1201	1178	17	(	(	-LRB-
cord-022561-rv5j1201	1178	18	e.g.	e.g.	RB
cord-022561-rv5j1201	1178	19	,	,	,
cord-022561-rv5j1201	1178	20	chronic	chronic	JJ
cord-022561-rv5j1201	1178	21	lymphocytic	lymphocytic	JJ
cord-022561-rv5j1201	1178	22	leukemia	leukemia	NN
cord-022561-rv5j1201	1178	23	and	and	CC
cord-022561-rv5j1201	1178	24	small	small	JJ
cord-022561-rv5j1201	1178	25	lymphocytic	lymphocytic	JJ
cord-022561-rv5j1201	1178	26	lymphoma	lymphoma	NN
cord-022561-rv5j1201	1178	27	)	)	-RRB-
cord-022561-rv5j1201	1178	28	,	,	,
cord-022561-rv5j1201	1178	29	and	and	CC
cord-022561-rv5j1201	1178	30	the	the	DT
cord-022561-rv5j1201	1178	31	designation	designation	NN
cord-022561-rv5j1201	1178	32	of	of	IN
cord-022561-rv5j1201	1178	33	lymphoma	lymphoma	NN
cord-022561-rv5j1201	1178	34	or	or	CC
cord-022561-rv5j1201	1178	35	leukemia	leukemia	NN
cord-022561-rv5j1201	1178	36	is	be	VBZ
cord-022561-rv5j1201	1178	37	placed	place	VBN
cord-022561-rv5j1201	1178	38	on	on	IN
cord-022561-rv5j1201	1178	39	the	the	DT
cord-022561-rv5j1201	1178	40	tissue	tissue	NN
cord-022561-rv5j1201	1178	41	with	with	IN
cord-022561-rv5j1201	1178	42	the	the	DT
cord-022561-rv5j1201	1178	43	largest	large	JJS
cord-022561-rv5j1201	1178	44	tumor	tumor	NN
cord-022561-rv5j1201	1178	45	burden	burden	NN
cord-022561-rv5j1201	1178	46	.	.	.
cord-022561-rv5j1201	1179	1	Based	base	VBN
cord-022561-rv5j1201	1179	2	on	on	IN
cord-022561-rv5j1201	1179	3	their	-PRON-	PRP$
cord-022561-rv5j1201	1179	4	degree	degree	NN
cord-022561-rv5j1201	1179	5	of	of	IN
cord-022561-rv5j1201	1179	6	differentiation	differentiation	NN
cord-022561-rv5j1201	1179	7	,	,	,
cord-022561-rv5j1201	1179	8	leukemias	leukemia	NNS
cord-022561-rv5j1201	1179	9	are	be	VBP
cord-022561-rv5j1201	1179	10	classified	classify	VBN
cord-022561-rv5j1201	1179	11	as	as	IN
cord-022561-rv5j1201	1179	12	acute	acute	JJ
cord-022561-rv5j1201	1179	13	or	or	CC
cord-022561-rv5j1201	1179	14	chronic	chronic	JJ
cord-022561-rv5j1201	1179	15	.	.	.
cord-022561-rv5j1201	1180	1	Acute	acute	JJ
cord-022561-rv5j1201	1180	2	leukemias	leukemia	NNS
cord-022561-rv5j1201	1180	3	are	be	VBP
cord-022561-rv5j1201	1180	4	poorly	poorly	RB
cord-022561-rv5j1201	1180	5	differentiated	differentiate	VBN
cord-022561-rv5j1201	1180	6	or	or	CC
cord-022561-rv5j1201	1180	7	undifferentiated	undifferentiated	JJ
cord-022561-rv5j1201	1180	8	,	,	,
cord-022561-rv5j1201	1180	9	meaning	mean	VBG
cord-022561-rv5j1201	1180	10	that	that	IN
cord-022561-rv5j1201	1180	11	there	there	EX
cord-022561-rv5j1201	1180	12	are	be	VBP
cord-022561-rv5j1201	1180	13	high	high	JJ
cord-022561-rv5j1201	1180	14	percentages	percentage	NNS
cord-022561-rv5j1201	1180	15	of	of	IN
cord-022561-rv5j1201	1180	16	early	early	JJ
cord-022561-rv5j1201	1180	17	progenitor	progenitor	NN
cord-022561-rv5j1201	1180	18	and	and	CC
cord-022561-rv5j1201	1180	19	precursor	precursor	NN
cord-022561-rv5j1201	1180	20	cells	cell	NNS
cord-022561-rv5j1201	1180	21	,	,	,
cord-022561-rv5j1201	1180	22	including	include	VBG
cord-022561-rv5j1201	1180	23	lymphoblasts	lymphoblast	NNS
cord-022561-rv5j1201	1180	24	,	,	,
cord-022561-rv5j1201	1180	25	myeloblasts	myeloblasts	NNPS
cord-022561-rv5j1201	1180	26	,	,	,
cord-022561-rv5j1201	1180	27	monoblasts	monoblast	NNS
cord-022561-rv5j1201	1180	28	,	,	,
cord-022561-rv5j1201	1180	29	erythroblasts	erythroblast	NNS
cord-022561-rv5j1201	1180	30	,	,	,
cord-022561-rv5j1201	1180	31	and/or	and/or	CC
cord-022561-rv5j1201	1180	32	megakaryoblasts	megakaryoblast	NNS
cord-022561-rv5j1201	1180	33	.	.	.
cord-022561-rv5j1201	1181	1	In	in	IN
cord-022561-rv5j1201	1181	2	contrast	contrast	NN
cord-022561-rv5j1201	1181	3	,	,	,
cord-022561-rv5j1201	1181	4	well	well	RB
cord-022561-rv5j1201	1181	5	-	-	HYPH
cord-022561-rv5j1201	1181	6	differentiated	differentiate	VBN
cord-022561-rv5j1201	1181	7	cells	cell	NNS
cord-022561-rv5j1201	1181	8	predominate	predominate	VBP
cord-022561-rv5j1201	1181	9	in	in	IN
cord-022561-rv5j1201	1181	10	chronic	chronic	JJ
cord-022561-rv5j1201	1181	11	leukemias	leukemia	NNS
cord-022561-rv5j1201	1181	12	.	.	.
cord-022561-rv5j1201	1182	1	Because	because	IN
cord-022561-rv5j1201	1182	2	well	well	RB
cord-022561-rv5j1201	1182	3	-	-	HYPH
cord-022561-rv5j1201	1182	4	differentiated	differentiate	VBN
cord-022561-rv5j1201	1182	5	cells	cell	NNS
cord-022561-rv5j1201	1182	6	also	also	RB
cord-022561-rv5j1201	1182	7	predominate	predominate	VBP
cord-022561-rv5j1201	1182	8	with	with	IN
cord-022561-rv5j1201	1182	9	nonneoplastic	nonneoplastic	JJ
cord-022561-rv5j1201	1182	10	proliferations	proliferation	NNS
cord-022561-rv5j1201	1182	11	,	,	,
cord-022561-rv5j1201	1182	12	chronic	chronic	JJ
cord-022561-rv5j1201	1182	13	leukemias	leukemia	NNS
cord-022561-rv5j1201	1182	14	must	must	MD
cord-022561-rv5j1201	1182	15	be	be	VB
cord-022561-rv5j1201	1182	16	differentiated	differentiate	VBN
cord-022561-rv5j1201	1182	17	from	from	IN
cord-022561-rv5j1201	1182	18	reactive	reactive	JJ
cord-022561-rv5j1201	1182	19	processes	process	NNS
cord-022561-rv5j1201	1182	20	,	,	,
cord-022561-rv5j1201	1182	21	such	such	JJ
cord-022561-rv5j1201	1182	22	as	as	IN
cord-022561-rv5j1201	1182	23	those	those	DT
cord-022561-rv5j1201	1182	24	cells	cell	NNS
cord-022561-rv5j1201	1182	25	that	that	WDT
cord-022561-rv5j1201	1182	26	occur	occur	VBP
cord-022561-rv5j1201	1182	27	in	in	IN
cord-022561-rv5j1201	1182	28	chronic	chronic	JJ
cord-022561-rv5j1201	1182	29	and/or	and/or	CC
cord-022561-rv5j1201	1182	30	granulomatous	granulomatous	JJ
cord-022561-rv5j1201	1182	31	inflammation	inflammation	NN
cord-022561-rv5j1201	1182	32	.	.	.
cord-022561-rv5j1201	1183	1	Diagnosis	diagnosis	NN
cord-022561-rv5j1201	1183	2	of	of	IN
cord-022561-rv5j1201	1183	3	chronic	chronic	JJ
cord-022561-rv5j1201	1183	4	leukemia	leukemia	NN
cord-022561-rv5j1201	1183	5	is	be	VBZ
cord-022561-rv5j1201	1183	6	often	often	RB
cord-022561-rv5j1201	1183	7	made	make	VBN
cord-022561-rv5j1201	1183	8	by	by	IN
cord-022561-rv5j1201	1183	9	excluding	exclude	VBG
cord-022561-rv5j1201	1183	10	all	all	DT
cord-022561-rv5j1201	1183	11	other	other	JJ
cord-022561-rv5j1201	1183	12	causes	cause	NNS
cord-022561-rv5j1201	1183	13	for	for	IN
cord-022561-rv5j1201	1183	14	the	the	DT
cord-022561-rv5j1201	1183	15	proliferating	proliferate	VBG
cord-022561-rv5j1201	1183	16	cell	cell	NN
cord-022561-rv5j1201	1183	17	type	type	NN
cord-022561-rv5j1201	1183	18	.	.	.
cord-022561-rv5j1201	1184	1	For	for	IN
cord-022561-rv5j1201	1184	2	example	example	NN
cord-022561-rv5j1201	1184	3	,	,	,
cord-022561-rv5j1201	1184	4	causes	cause	NNS
cord-022561-rv5j1201	1184	5	of	of	IN
cord-022561-rv5j1201	1184	6	relative	relative	JJ
cord-022561-rv5j1201	1184	7	and	and	CC
cord-022561-rv5j1201	1184	8	secondary	secondary	JJ
cord-022561-rv5j1201	1184	9	erythrocytosis	erythrocytosis	NN
cord-022561-rv5j1201	1184	10	are	be	VBP
cord-022561-rv5j1201	1184	11	excluded	exclude	VBN
cord-022561-rv5j1201	1184	12	to	to	TO
cord-022561-rv5j1201	1184	13	be	be	VB
cord-022561-rv5j1201	1184	14	able	able	JJ
cord-022561-rv5j1201	1184	15	to	to	TO
cord-022561-rv5j1201	1184	16	diagnose	diagnose	VB
cord-022561-rv5j1201	1184	17	polycythemia	polycythemia	NN
cord-022561-rv5j1201	1184	18	vera	vera	NN
cord-022561-rv5j1201	1184	19	.	.	.
cord-022561-rv5j1201	1185	1	Furthermore	furthermore	RB
cord-022561-rv5j1201	1185	2	,	,	,
cord-022561-rv5j1201	1185	3	the	the	DT
cord-022561-rv5j1201	1185	4	designation	designation	NN
cord-022561-rv5j1201	1185	5	of	of	IN
cord-022561-rv5j1201	1185	6	acute	acute	JJ
cord-022561-rv5j1201	1185	7	or	or	CC
cord-022561-rv5j1201	1185	8	chronic	chronic	JJ
cord-022561-rv5j1201	1185	9	also	also	RB
cord-022561-rv5j1201	1185	10	refers	refer	VBZ
cord-022561-rv5j1201	1185	11	to	to	IN
cord-022561-rv5j1201	1185	12	the	the	DT
cord-022561-rv5j1201	1185	13	disease	disease	NN
cord-022561-rv5j1201	1185	14	's	's	POS
cord-022561-rv5j1201	1185	15	clinical	clinical	JJ
cord-022561-rv5j1201	1185	16	course	course	NN
cord-022561-rv5j1201	1185	17	.	.	.
cord-022561-rv5j1201	1186	1	Acute	acute	JJ
cord-022561-rv5j1201	1186	2	leukemias	leukemia	NNS
cord-022561-rv5j1201	1186	3	tend	tend	VBP
cord-022561-rv5j1201	1186	4	to	to	TO
cord-022561-rv5j1201	1186	5	have	have	VB
cord-022561-rv5j1201	1186	6	an	an	DT
cord-022561-rv5j1201	1186	7	acute	acute	JJ
cord-022561-rv5j1201	1186	8	onset	onset	NN
cord-022561-rv5j1201	1186	9	of	of	IN
cord-022561-rv5j1201	1186	10	severe	severe	JJ
cord-022561-rv5j1201	1186	11	and	and	CC
cord-022561-rv5j1201	1186	12	rapidly	rapidly	RB
cord-022561-rv5j1201	1186	13	progressive	progressive	JJ
cord-022561-rv5j1201	1186	14	clinical	clinical	JJ
cord-022561-rv5j1201	1186	15	signs	sign	NNS
cord-022561-rv5j1201	1186	16	,	,	,
cord-022561-rv5j1201	1186	17	whereas	whereas	IN
cord-022561-rv5j1201	1186	18	animals	animal	NNS
cord-022561-rv5j1201	1186	19	with	with	IN
cord-022561-rv5j1201	1186	20	chronic	chronic	JJ
cord-022561-rv5j1201	1186	21	leukemia	leukemia	NN
cord-022561-rv5j1201	1186	22	for	for	IN
cord-022561-rv5j1201	1186	23	destruction	destruction	NN
cord-022561-rv5j1201	1186	24	.	.	.
cord-022561-rv5j1201	1187	1	Marrow	Marrow	NNP
cord-022561-rv5j1201	1187	2	lymphocytosis	lymphocytosis	NN
cord-022561-rv5j1201	1187	3	and	and	CC
cord-022561-rv5j1201	1187	4	plasmacytosis	plasmacytosis	NN
cord-022561-rv5j1201	1187	5	may	may	MD
cord-022561-rv5j1201	1187	6	be	be	VB
cord-022561-rv5j1201	1187	7	marked	mark	VBN
cord-022561-rv5j1201	1187	8	(	(	-LRB-
cord-022561-rv5j1201	1187	9	e.g.	e.g.	RB
cord-022561-rv5j1201	1187	10	,	,	,
cord-022561-rv5j1201	1187	11	>	>	XX
cord-022561-rv5j1201	1188	1	60	60	CD
cord-022561-rv5j1201	1188	2	%	%	NN
cord-022561-rv5j1201	1188	3	of	of	IN
cord-022561-rv5j1201	1188	4	nucleated	nucleated	JJ
cord-022561-rv5j1201	1188	5	cells	cell	NNS
cord-022561-rv5j1201	1188	6	)	)	-RRB-
cord-022561-rv5j1201	1188	7	.	.	.
cord-022561-rv5j1201	1189	1	The	the	DT
cord-022561-rv5j1201	1189	2	diagnosis	diagnosis	NN
cord-022561-rv5j1201	1189	3	may	may	MD
cord-022561-rv5j1201	1189	4	be	be	VB
cord-022561-rv5j1201	1189	5	supported	support	VBN
cord-022561-rv5j1201	1189	6	by	by	IN
cord-022561-rv5j1201	1189	7	flow	flow	NN
cord-022561-rv5j1201	1189	8	cytometric	cytometric	NN
cord-022561-rv5j1201	1189	9	detection	detection	NN
cord-022561-rv5j1201	1189	10	of	of	IN
cord-022561-rv5j1201	1189	11	immunoglobulin	immunoglobulin	NN
cord-022561-rv5j1201	1189	12	bound	bind	VBN
cord-022561-rv5j1201	1189	13	to	to	IN
cord-022561-rv5j1201	1189	14	neutrophils	neutrophil	NNS
cord-022561-rv5j1201	1189	15	but	but	CC
cord-022561-rv5j1201	1189	16	is	be	VBZ
cord-022561-rv5j1201	1189	17	most	most	RBS
cord-022561-rv5j1201	1189	18	often	often	RB
cord-022561-rv5j1201	1189	19	made	make	VBN
cord-022561-rv5j1201	1189	20	on	on	IN
cord-022561-rv5j1201	1189	21	the	the	DT
cord-022561-rv5j1201	1189	22	basis	basis	NN
cord-022561-rv5j1201	1189	23	of	of	IN
cord-022561-rv5j1201	1189	24	exclusion	exclusion	NN
cord-022561-rv5j1201	1189	25	of	of	IN
cord-022561-rv5j1201	1189	26	other	other	JJ
cord-022561-rv5j1201	1189	27	causes	cause	NNS
cord-022561-rv5j1201	1189	28	of	of	IN
cord-022561-rv5j1201	1189	29	neutropenia	neutropenia	NN
cord-022561-rv5j1201	1189	30	and	and	CC
cord-022561-rv5j1201	1189	31	response	response	NN
cord-022561-rv5j1201	1189	32	to	to	IN
cord-022561-rv5j1201	1189	33	immunosuppressive	immunosuppressive	JJ
cord-022561-rv5j1201	1189	34	therapy	therapy	NN
cord-022561-rv5j1201	1189	35	.	.	.
cord-022561-rv5j1201	1190	1	Immune	immune	NN
cord-022561-rv5j1201	1190	2	-	-	HYPH
cord-022561-rv5j1201	1190	3	Mediated	mediate	VBN
cord-022561-rv5j1201	1190	4	Thrombocytopenia	Thrombocytopenia	NNP
cord-022561-rv5j1201	1190	5	.	.	.
cord-022561-rv5j1201	1191	1	Immune	immune	NN
cord-022561-rv5j1201	1191	2	-	-	HYPH
cord-022561-rv5j1201	1191	3	mediated	mediate	VBN
cord-022561-rv5j1201	1191	4	thrombocytopenia	thrombocytopenia	NN
cord-022561-rv5j1201	1191	5	(	(	-LRB-
cord-022561-rv5j1201	1191	6	IMTP	IMTP	NNP
cord-022561-rv5j1201	1191	7	)	)	-RRB-
cord-022561-rv5j1201	1191	8	is	be	VBZ
cord-022561-rv5j1201	1191	9	a	a	DT
cord-022561-rv5j1201	1191	10	condition	condition	NN
cord-022561-rv5j1201	1191	11	characterized	characterize	VBN
cord-022561-rv5j1201	1191	12	by	by	IN
cord-022561-rv5j1201	1191	13	immunemediated	immunemediated	JJ
cord-022561-rv5j1201	1191	14	destruction	destruction	NN
cord-022561-rv5j1201	1191	15	of	of	IN
cord-022561-rv5j1201	1191	16	platelets	platelet	NNS
cord-022561-rv5j1201	1191	17	.	.	.
cord-022561-rv5j1201	1192	1	It	-PRON-	PRP
cord-022561-rv5j1201	1192	2	is	be	VBZ
cord-022561-rv5j1201	1192	3	a	a	DT
cord-022561-rv5j1201	1192	4	fairly	fairly	RB
cord-022561-rv5j1201	1192	5	common	common	JJ
cord-022561-rv5j1201	1192	6	condition	condition	NN
cord-022561-rv5j1201	1192	7	in	in	IN
cord-022561-rv5j1201	1192	8	dogs	dog	NNS
cord-022561-rv5j1201	1192	9	and	and	CC
cord-022561-rv5j1201	1192	10	is	be	VBZ
cord-022561-rv5j1201	1192	11	less	less	RBR
cord-022561-rv5j1201	1192	12	frequent	frequent	JJ
cord-022561-rv5j1201	1192	13	in	in	IN
cord-022561-rv5j1201	1192	14	horses	horse	NNS
cord-022561-rv5j1201	1192	15	and	and	CC
cord-022561-rv5j1201	1192	16	cats	cat	NNS
cord-022561-rv5j1201	1192	17	.	.	.
cord-022561-rv5j1201	1193	1	The	the	DT
cord-022561-rv5j1201	1193	2	disease	disease	NN
cord-022561-rv5j1201	1193	3	is	be	VBZ
cord-022561-rv5j1201	1193	4	usually	usually	RB
cord-022561-rv5j1201	1193	5	idiopathic	idiopathic	JJ
cord-022561-rv5j1201	1193	6	but	but	CC
cord-022561-rv5j1201	1193	7	may	may	MD
cord-022561-rv5j1201	1193	8	be	be	VB
cord-022561-rv5j1201	1193	9	secondary	secondary	JJ
cord-022561-rv5j1201	1193	10	to	to	IN
cord-022561-rv5j1201	1193	11	infection	infection	NN
cord-022561-rv5j1201	1193	12	(	(	-LRB-
cord-022561-rv5j1201	1193	13	e.g.	e.g.	RB
cord-022561-rv5j1201	1193	14	,	,	,
cord-022561-rv5j1201	1193	15	equine	equine	JJ
cord-022561-rv5j1201	1193	16	infectious	infectious	JJ
cord-022561-rv5j1201	1193	17	anemia	anemia	NN
cord-022561-rv5j1201	1193	18	and	and	CC
cord-022561-rv5j1201	1193	19	ehrlichiosis	ehrlichiosis	NNP
cord-022561-rv5j1201	1193	20	)	)	-RRB-
cord-022561-rv5j1201	1193	21	,	,	,
cord-022561-rv5j1201	1193	22	drug	drug	NNP
cord-022561-rv5j1201	1193	23	administration	administration	NN
cord-022561-rv5j1201	1193	24	(	(	-LRB-
cord-022561-rv5j1201	1193	25	e.g.	e.g.	RB
cord-022561-rv5j1201	1193	26	,	,	,
cord-022561-rv5j1201	1193	27	cephalosporins	cephalosporin	NNS
cord-022561-rv5j1201	1193	28	and	and	CC
cord-022561-rv5j1201	1193	29	sulfonamides	sulfonamide	NNS
cord-022561-rv5j1201	1193	30	)	)	-RRB-
cord-022561-rv5j1201	1193	31	,	,	,
cord-022561-rv5j1201	1193	32	neoplasia	neoplasia	NN
cord-022561-rv5j1201	1193	33	,	,	,
cord-022561-rv5j1201	1193	34	and	and	CC
cord-022561-rv5j1201	1193	35	other	other	JJ
cord-022561-rv5j1201	1193	36	immunemediated	immunemediated	JJ
cord-022561-rv5j1201	1193	37	diseases	disease	NNS
cord-022561-rv5j1201	1193	38	.	.	.
cord-022561-rv5j1201	1194	1	When	when	WRB
cord-022561-rv5j1201	1194	2	immune	immune	NN
cord-022561-rv5j1201	1194	3	-	-	HYPH
cord-022561-rv5j1201	1194	4	mediated	mediate	VBN
cord-022561-rv5j1201	1194	5	thrombocytopenia	thrombocytopenia	NN
cord-022561-rv5j1201	1194	6	occurs	occur	VBZ
cord-022561-rv5j1201	1194	7	together	together	RB
cord-022561-rv5j1201	1194	8	with	with	IN
cord-022561-rv5j1201	1194	9	immune	immune	NN
cord-022561-rv5j1201	1194	10	-	-	HYPH
cord-022561-rv5j1201	1194	11	mediated	mediate	VBN
cord-022561-rv5j1201	1194	12	hemolytic	hemolytic	JJ
cord-022561-rv5j1201	1194	13	anemia	anemia	NN
cord-022561-rv5j1201	1194	14	,	,	,
cord-022561-rv5j1201	1194	15	the	the	DT
cord-022561-rv5j1201	1194	16	condition	condition	NN
cord-022561-rv5j1201	1194	17	is	be	VBZ
cord-022561-rv5j1201	1194	18	called	call	VBN
cord-022561-rv5j1201	1194	19	Evans	Evans	NNP
cord-022561-rv5j1201	1194	20	's	's	POS
cord-022561-rv5j1201	1194	21	syndrome	syndrome	NN
cord-022561-rv5j1201	1194	22	.	.	.
cord-022561-rv5j1201	1195	1	The	the	DT
cord-022561-rv5j1201	1195	2	thrombocytopenia	thrombocytopenia	NN
cord-022561-rv5j1201	1195	3	is	be	VBZ
cord-022561-rv5j1201	1195	4	often	often	RB
cord-022561-rv5j1201	1195	5	severe	severe	JJ
cord-022561-rv5j1201	1195	6	(	(	-LRB-
cord-022561-rv5j1201	1195	7	e.g.	e.g.	RB
cord-022561-rv5j1201	1195	8	,	,	,
cord-022561-rv5j1201	1195	9	<	<	XX
cord-022561-rv5j1201	1195	10	20,000	20,000	CD
cord-022561-rv5j1201	1195	11	platelets/µL	platelets/µl	JJ
cord-022561-rv5j1201	1195	12	)	)	-RRB-
cord-022561-rv5j1201	1195	13	,	,	,
cord-022561-rv5j1201	1195	14	resulting	result	VBG
cord-022561-rv5j1201	1195	15	in	in	IN
cord-022561-rv5j1201	1195	16	varying	vary	VBG
cord-022561-rv5j1201	1195	17	degrees	degree	NNS
cord-022561-rv5j1201	1195	18	of	of	IN
cord-022561-rv5j1201	1195	19	bleeding	bleed	VBG
cord-022561-rv5j1201	1195	20	tendencies	tendency	NNS
cord-022561-rv5j1201	1195	21	,	,	,
cord-022561-rv5j1201	1195	22	mainly	mainly	RB
cord-022561-rv5j1201	1195	23	in	in	IN
cord-022561-rv5j1201	1195	24	skin	skin	NN
cord-022561-rv5j1201	1195	25	and	and	CC
cord-022561-rv5j1201	1195	26	mucous	mucous	JJ
cord-022561-rv5j1201	1195	27	membranes	membrane	NNS
cord-022561-rv5j1201	1195	28	.	.	.
cord-022561-rv5j1201	1196	1	Microscopically	microscopically	RB
cord-022561-rv5j1201	1196	2	,	,	,
cord-022561-rv5j1201	1196	3	there	there	EX
cord-022561-rv5j1201	1196	4	are	be	VBP
cord-022561-rv5j1201	1196	5	multifocal	multifocal	JJ
cord-022561-rv5j1201	1196	6	perivascular	perivascular	JJ
cord-022561-rv5j1201	1196	7	hemorrhages	hemorrhage	NNS
cord-022561-rv5j1201	1196	8	in	in	IN
cord-022561-rv5j1201	1196	9	multiple	multiple	JJ
cord-022561-rv5j1201	1196	10	tissues	tissue	NNS
cord-022561-rv5j1201	1196	11	,	,	,
cord-022561-rv5j1201	1196	12	and	and	CC
cord-022561-rv5j1201	1196	13	the	the	DT
cord-022561-rv5j1201	1196	14	bone	bone	NN
cord-022561-rv5j1201	1196	15	marrow	marrow	NN
cord-022561-rv5j1201	1196	16	exhibits	exhibit	VBZ
cord-022561-rv5j1201	1196	17	megakaryocytic	megakaryocytic	JJ
cord-022561-rv5j1201	1196	18	and	and	CC
cord-022561-rv5j1201	1196	19	erythroid	erythroid	JJ
cord-022561-rv5j1201	1196	20	hyperplasia	hyperplasia	NN
cord-022561-rv5j1201	1196	21	.	.	.
cord-022561-rv5j1201	1197	1	Rarely	rarely	RB
cord-022561-rv5j1201	1197	2	,	,	,
cord-022561-rv5j1201	1197	3	immune	immune	JJ
cord-022561-rv5j1201	1197	4	-	-	HYPH
cord-022561-rv5j1201	1197	5	mediated	mediate	VBN
cord-022561-rv5j1201	1197	6	destruction	destruction	NN
cord-022561-rv5j1201	1197	7	of	of	IN
cord-022561-rv5j1201	1197	8	megakaryocytes	megakaryocyte	NNS
cord-022561-rv5j1201	1197	9	may	may	MD
cord-022561-rv5j1201	1197	10	cause	cause	VB
cord-022561-rv5j1201	1197	11	megakaryocytic	megakaryocytic	JJ
cord-022561-rv5j1201	1197	12	hypoplasia	hypoplasia	NNP
cord-022561-rv5j1201	1197	13	,	,	,
cord-022561-rv5j1201	1197	14	termed	term	VBN
cord-022561-rv5j1201	1197	15	amegakaryocytic	amegakaryocytic	JJ
cord-022561-rv5j1201	1197	16	thrombocytopenia	thrombocytopenia	NN
cord-022561-rv5j1201	1197	17	.	.	.
cord-022561-rv5j1201	1198	1	Neonatal	Neonatal	NNP
cord-022561-rv5j1201	1198	2	Alloimmune	Alloimmune	NNP
cord-022561-rv5j1201	1198	3	Thrombocytopenia	Thrombocytopenia	NNP
cord-022561-rv5j1201	1198	4	.	.	.
cord-022561-rv5j1201	1199	1	A	a	DT
cord-022561-rv5j1201	1199	2	form	form	NN
cord-022561-rv5j1201	1199	3	of	of	IN
cord-022561-rv5j1201	1199	4	immune	immune	NN
cord-022561-rv5j1201	1199	5	-	-	HYPH
cord-022561-rv5j1201	1199	6	mediated	mediate	VBN
cord-022561-rv5j1201	1199	7	thrombocytopenia	thrombocytopenia	NN
cord-022561-rv5j1201	1199	8	,	,	,
cord-022561-rv5j1201	1199	9	known	know	VBN
cord-022561-rv5j1201	1199	10	as	as	IN
cord-022561-rv5j1201	1199	11	neonatal	neonatal	JJ
cord-022561-rv5j1201	1199	12	alloimmune	alloimmune	NNP
cord-022561-rv5j1201	1199	13	thrombocytopenia	thrombocytopenia	NN
cord-022561-rv5j1201	1199	14	,	,	,
cord-022561-rv5j1201	1199	15	is	be	VBZ
cord-022561-rv5j1201	1199	16	recognized	recognize	VBN
cord-022561-rv5j1201	1199	17	in	in	IN
cord-022561-rv5j1201	1199	18	neonatal	neonatal	JJ
cord-022561-rv5j1201	1199	19	pigs	pig	NNS
cord-022561-rv5j1201	1199	20	and	and	CC
cord-022561-rv5j1201	1199	21	foals	foal	NNS
cord-022561-rv5j1201	1199	22	.	.	.
cord-022561-rv5j1201	1200	1	The	the	DT
cord-022561-rv5j1201	1200	2	pathogenesis	pathogenesis	NN
cord-022561-rv5j1201	1200	3	of	of	IN
cord-022561-rv5j1201	1200	4	this	this	DT
cord-022561-rv5j1201	1200	5	disease	disease	NN
cord-022561-rv5j1201	1200	6	is	be	VBZ
cord-022561-rv5j1201	1200	7	virtually	virtually	RB
cord-022561-rv5j1201	1200	8	identical	identical	JJ
cord-022561-rv5j1201	1200	9	to	to	IN
cord-022561-rv5j1201	1200	10	that	that	DT
cord-022561-rv5j1201	1200	11	of	of	IN
cord-022561-rv5j1201	1200	12	neonatal	neonatal	JJ
cord-022561-rv5j1201	1200	13	isoerythrolysis	isoerythrolysis	NN
cord-022561-rv5j1201	1200	14	as	as	IN
cord-022561-rv5j1201	1200	15	a	a	DT
cord-022561-rv5j1201	1200	16	cause	cause	NN
cord-022561-rv5j1201	1200	17	of	of	IN
cord-022561-rv5j1201	1200	18	anemia	anemia	NN
cord-022561-rv5j1201	1200	19	:	:	:
cord-022561-rv5j1201	1200	20	a	a	DT
cord-022561-rv5j1201	1200	21	neonate	neonate	NN
cord-022561-rv5j1201	1200	22	inheriting	inherit	VBG
cord-022561-rv5j1201	1200	23	paternal	paternal	JJ
cord-022561-rv5j1201	1200	24	platelet	platelet	NN
cord-022561-rv5j1201	1200	25	antigens	antigen	NNS
cord-022561-rv5j1201	1200	26	absorbs	absorb	VBZ
cord-022561-rv5j1201	1200	27	maternal	maternal	JJ
cord-022561-rv5j1201	1200	28	antibodies	antibody	NNS
cord-022561-rv5j1201	1200	29	against	against	IN
cord-022561-rv5j1201	1200	30	these	these	DT
cord-022561-rv5j1201	1200	31	antigens	antigen	NNS
cord-022561-rv5j1201	1200	32	through	through	IN
cord-022561-rv5j1201	1200	33	the	the	DT
cord-022561-rv5j1201	1200	34	colostrum	colostrum	NN
cord-022561-rv5j1201	1200	35	.	.	.
cord-022561-rv5j1201	1201	1	In	in	IN
cord-022561-rv5j1201	1201	2	principle	principle	NN
cord-022561-rv5j1201	1201	3	,	,	,
cord-022561-rv5j1201	1201	4	a	a	DT
cord-022561-rv5j1201	1201	5	similar	similar	JJ
cord-022561-rv5j1201	1201	6	situation	situation	NN
cord-022561-rv5j1201	1201	7	may	may	MD
cord-022561-rv5j1201	1201	8	occur	occur	VB
cord-022561-rv5j1201	1201	9	after	after	IN
cord-022561-rv5j1201	1201	10	platelet	platelet	NN
cord-022561-rv5j1201	1201	11	-	-	HYPH
cord-022561-rv5j1201	1201	12	incompatible	incompatible	JJ
cord-022561-rv5j1201	1201	13	transfusion	transfusion	NN
cord-022561-rv5j1201	1201	14	of	of	IN
cord-022561-rv5j1201	1201	15	blood	blood	NN
cord-022561-rv5j1201	1201	16	or	or	CC
cord-022561-rv5j1201	1201	17	blood	blood	NN
cord-022561-rv5j1201	1201	18	products	product	NNS
cord-022561-rv5j1201	1201	19	containing	contain	VBG
cord-022561-rv5j1201	1201	20	platelets	platelet	NNS
cord-022561-rv5j1201	1201	21	.	.	.
cord-022561-rv5j1201	1202	1	Gross	gross	JJ
cord-022561-rv5j1201	1202	2	and	and	CC
cord-022561-rv5j1201	1202	3	microscopic	microscopic	JJ
cord-022561-rv5j1201	1202	4	changes	change	NNS
cord-022561-rv5j1201	1202	5	are	be	VBP
cord-022561-rv5j1201	1202	6	similar	similar	JJ
cord-022561-rv5j1201	1202	7	to	to	IN
cord-022561-rv5j1201	1202	8	those	those	DT
cord-022561-rv5j1201	1202	9	of	of	IN
cord-022561-rv5j1201	1202	10	immune	immune	NN
cord-022561-rv5j1201	1202	11	-	-	HYPH
cord-022561-rv5j1201	1202	12	mediated	mediate	VBN
cord-022561-rv5j1201	1202	13	thrombocytopenia	thrombocytopenia	NN
cord-022561-rv5j1201	1202	14	except	except	IN
cord-022561-rv5j1201	1202	15	that	that	IN
cord-022561-rv5j1201	1202	16	the	the	DT
cord-022561-rv5j1201	1202	17	animal	animal	NN
cord-022561-rv5j1201	1202	18	is	be	VBZ
cord-022561-rv5j1201	1202	19	young	young	JJ
cord-022561-rv5j1201	1202	20	(	(	-LRB-
cord-022561-rv5j1201	1202	21	e.g.	e.g.	RB
cord-022561-rv5j1201	1202	22	,	,	,
cord-022561-rv5j1201	1202	23	1	1	CD
cord-022561-rv5j1201	1202	24	to	to	TO
cord-022561-rv5j1201	1202	25	3	3	CD
cord-022561-rv5j1201	1202	26	days	day	NNS
cord-022561-rv5j1201	1202	27	)	)	-RRB-
cord-022561-rv5j1201	1202	28	.	.	.
cord-022561-rv5j1201	1203	1	Hemophagocytic	Hemophagocytic	NNP
cord-022561-rv5j1201	1203	2	Syndrome	Syndrome	NNP
cord-022561-rv5j1201	1203	3	.	.	.
cord-022561-rv5j1201	1204	1	Hemophagocytic	hemophagocytic	JJ
cord-022561-rv5j1201	1204	2	syndrome	syndrome	NN
cord-022561-rv5j1201	1204	3	is	be	VBZ
cord-022561-rv5j1201	1204	4	a	a	DT
cord-022561-rv5j1201	1204	5	term	term	NN
cord-022561-rv5j1201	1204	6	used	use	VBN
cord-022561-rv5j1201	1204	7	to	to	TO
cord-022561-rv5j1201	1204	8	describe	describe	VB
cord-022561-rv5j1201	1204	9	the	the	DT
cord-022561-rv5j1201	1204	10	proliferation	proliferation	NN
cord-022561-rv5j1201	1204	11	of	of	IN
cord-022561-rv5j1201	1204	12	nonneoplastic	nonneoplastic	NNP
cord-022561-rv5j1201	1204	13	(	(	-LRB-
cord-022561-rv5j1201	1204	14	i.e.	i.e.	FW
cord-022561-rv5j1201	1204	15	,	,	,
cord-022561-rv5j1201	1204	16	polyclonal	polyclonal	JJ
cord-022561-rv5j1201	1204	17	)	)	-RRB-
cord-022561-rv5j1201	1204	18	,	,	,
cord-022561-rv5j1201	1204	19	well	well	RB
cord-022561-rv5j1201	1204	20	-	-	HYPH
cord-022561-rv5j1201	1204	21	differentiated	differentiate	VBN
cord-022561-rv5j1201	1204	22	but	but	CC
cord-022561-rv5j1201	1204	23	highly	highly	RB
cord-022561-rv5j1201	1204	24	erythrophagic	erythrophagic	JJ
cord-022561-rv5j1201	1204	25	macrophages	macrophage	NNS
cord-022561-rv5j1201	1204	26	.	.	.
cord-022561-rv5j1201	1205	1	The	the	DT
cord-022561-rv5j1201	1205	2	condition	condition	NN
cord-022561-rv5j1201	1205	3	is	be	VBZ
cord-022561-rv5j1201	1205	4	rare	rare	JJ
cord-022561-rv5j1201	1205	5	but	but	CC
cord-022561-rv5j1201	1205	6	has	have	VBZ
cord-022561-rv5j1201	1205	7	been	be	VBN
cord-022561-rv5j1201	1205	8	recognized	recognize	VBN
cord-022561-rv5j1201	1205	9	in	in	IN
cord-022561-rv5j1201	1205	10	dogs	dog	NNS
cord-022561-rv5j1201	1205	11	and	and	CC
cord-022561-rv5j1201	1205	12	cats	cat	NNS
cord-022561-rv5j1201	1205	13	.	.	.
cord-022561-rv5j1201	1206	1	Unlike	unlike	IN
cord-022561-rv5j1201	1206	2	hemophagocytic	hemophagocytic	JJ
cord-022561-rv5j1201	1206	3	histiocytic	histiocytic	JJ
cord-022561-rv5j1201	1206	4	sarcoma	sarcoma	NN
cord-022561-rv5j1201	1206	5	,	,	,
cord-022561-rv5j1201	1206	6	which	which	WDT
cord-022561-rv5j1201	1206	7	is	be	VBZ
cord-022561-rv5j1201	1206	8	a	a	DT
cord-022561-rv5j1201	1206	9	neoplastic	neoplastic	JJ
cord-022561-rv5j1201	1206	10	proliferation	proliferation	NN
cord-022561-rv5j1201	1206	11	of	of	IN
cord-022561-rv5j1201	1206	12	phagocytic	phagocytic	JJ
cord-022561-rv5j1201	1206	13	macrophages	macrophage	NNS
cord-022561-rv5j1201	1206	14	,	,	,
cord-022561-rv5j1201	1206	15	hemophagocytic	hemophagocytic	JJ
cord-022561-rv5j1201	1206	16	syndrome	syndrome	NN
cord-022561-rv5j1201	1206	17	is	be	VBZ
cord-022561-rv5j1201	1206	18	secondary	secondary	JJ
cord-022561-rv5j1201	1206	19	to	to	IN
cord-022561-rv5j1201	1206	20	an	an	DT
cord-022561-rv5j1201	1206	21	underlying	underlie	VBG
cord-022561-rv5j1201	1206	22	disease	disease	NN
cord-022561-rv5j1201	1206	23	,	,	,
cord-022561-rv5j1201	1206	24	such	such	JJ
cord-022561-rv5j1201	1206	25	as	as	IN
cord-022561-rv5j1201	1206	26	neoplasia	neoplasia	NN
cord-022561-rv5j1201	1206	27	,	,	,
cord-022561-rv5j1201	1206	28	infection	infection	NN
cord-022561-rv5j1201	1206	29	,	,	,
cord-022561-rv5j1201	1206	30	or	or	CC
cord-022561-rv5j1201	1206	31	an	an	DT
cord-022561-rv5j1201	1206	32	immune	immune	NN
cord-022561-rv5j1201	1206	33	-	-	HYPH
cord-022561-rv5j1201	1206	34	mediated	mediate	VBN
cord-022561-rv5j1201	1206	35	disorder	disorder	NN
cord-022561-rv5j1201	1206	36	.	.	.
cord-022561-rv5j1201	1207	1	The	the	DT
cord-022561-rv5j1201	1207	2	primary	primary	JJ
cord-022561-rv5j1201	1207	3	disease	disease	NN
cord-022561-rv5j1201	1207	4	process	process	NN
cord-022561-rv5j1201	1207	5	causes	cause	VBZ
cord-022561-rv5j1201	1207	6	increased	increase	VBN
cord-022561-rv5j1201	1207	7	production	production	NN
cord-022561-rv5j1201	1207	8	of	of	IN
cord-022561-rv5j1201	1207	9	stimulatory	stimulatory	JJ
cord-022561-rv5j1201	1207	10	cytokines	cytokine	NNS
cord-022561-rv5j1201	1207	11	,	,	,
cord-022561-rv5j1201	1207	12	which	which	WDT
cord-022561-rv5j1201	1207	13	results	result	VBZ
cord-022561-rv5j1201	1207	14	in	in	IN
cord-022561-rv5j1201	1207	15	macrophage	macrophage	NN
cord-022561-rv5j1201	1207	16	proliferation	proliferation	NN
cord-022561-rv5j1201	1207	17	and	and	CC
cord-022561-rv5j1201	1207	18	hyperactivation	hyperactivation	NN
cord-022561-rv5j1201	1207	19	.	.	.
cord-022561-rv5j1201	1208	1	These	these	DT
cord-022561-rv5j1201	1208	2	activated	activate	VBN
cord-022561-rv5j1201	1208	3	macrophages	macrophage	NNS
cord-022561-rv5j1201	1208	4	phagocytize	phagocytize	VBP
cord-022561-rv5j1201	1208	5	mature	mature	JJ
cord-022561-rv5j1201	1208	6	hematopoietic	hematopoietic	JJ
cord-022561-rv5j1201	1208	7	cells	cell	NNS
cord-022561-rv5j1201	1208	8	and	and	CC
cord-022561-rv5j1201	1208	9	hematopoietic	hematopoietic	JJ
cord-022561-rv5j1201	1208	10	precursors	precursor	NNS
cord-022561-rv5j1201	1208	11	at	at	IN
cord-022561-rv5j1201	1208	12	an	an	DT
cord-022561-rv5j1201	1208	13	enhanced	enhance	VBN
cord-022561-rv5j1201	1208	14	rate	rate	NN
cord-022561-rv5j1201	1208	15	,	,	,
cord-022561-rv5j1201	1208	16	resulting	result	VBG
cord-022561-rv5j1201	1208	17	in	in	IN
cord-022561-rv5j1201	1208	18	one	one	CD
cord-022561-rv5j1201	1208	19	or	or	CC
cord-022561-rv5j1201	1208	20	more	more	JJR
cord-022561-rv5j1201	1208	21	cytopenias	cytopenia	NNS
cord-022561-rv5j1201	1208	22	.	.	.
cord-022561-rv5j1201	1209	1	Affected	affected	JJ
cord-022561-rv5j1201	1209	2	animals	animal	NNS
cord-022561-rv5j1201	1209	3	usually	usually	RB
cord-022561-rv5j1201	1209	4	have	have	VBP
cord-022561-rv5j1201	1209	5	lesions	lesion	NNS
cord-022561-rv5j1201	1209	6	of	of	IN
cord-022561-rv5j1201	1209	7	the	the	DT
cord-022561-rv5j1201	1209	8	primary	primary	JJ
cord-022561-rv5j1201	1209	9	disease	disease	NN
cord-022561-rv5j1201	1209	10	,	,	,
cord-022561-rv5j1201	1209	11	as	as	RB
cord-022561-rv5j1201	1209	12	well	well	RB
cord-022561-rv5j1201	1209	13	as	as	IN
cord-022561-rv5j1201	1209	14	signs	sign	NNS
cord-022561-rv5j1201	1209	15	of	of	IN
cord-022561-rv5j1201	1209	16	the	the	DT
cord-022561-rv5j1201	1209	17	anemia	anemia	NN
cord-022561-rv5j1201	1209	18	(	(	-LRB-
cord-022561-rv5j1201	1209	19	e.g.	e.g.	RB
cord-022561-rv5j1201	1209	20	,	,	,
cord-022561-rv5j1201	1209	21	pale	pale	JJ
cord-022561-rv5j1201	1209	22	mucous	mucous	JJ
cord-022561-rv5j1201	1209	23	membranes	membrane	NNS
cord-022561-rv5j1201	1209	24	)	)	-RRB-
cord-022561-rv5j1201	1209	25	,	,	,
cord-022561-rv5j1201	1209	26	neutropenia	neutropenia	FW
cord-022561-rv5j1201	1209	27	(	(	-LRB-
cord-022561-rv5j1201	1209	28	e.g.	e.g.	RB
cord-022561-rv5j1201	1209	29	,	,	,
cord-022561-rv5j1201	1209	30	bacterial	bacterial	JJ
cord-022561-rv5j1201	1209	31	infections	infection	NNS
cord-022561-rv5j1201	1209	32	)	)	-RRB-
cord-022561-rv5j1201	1209	33	,	,	,
cord-022561-rv5j1201	1209	34	and	and	CC
cord-022561-rv5j1201	1209	35	thrombocytopenia	thrombocytopenia	NN
cord-022561-rv5j1201	1209	36	(	(	-LRB-
cord-022561-rv5j1201	1209	37	e.g.	e.g.	RB
cord-022561-rv5j1201	1209	38	,	,	,
cord-022561-rv5j1201	1209	39	petechiae	petechia	NNS
cord-022561-rv5j1201	1209	40	and	and	CC
cord-022561-rv5j1201	1209	41	ecchymoses	ecchymosis	NNS
cord-022561-rv5j1201	1209	42	)	)	-RRB-
cord-022561-rv5j1201	1209	43	.	.	.
cord-022561-rv5j1201	1210	1	Microscopically	microscopically	RB
cord-022561-rv5j1201	1210	2	,	,	,
cord-022561-rv5j1201	1210	3	phagocytic	phagocytic	JJ
cord-022561-rv5j1201	1210	4	macrophages	macrophage	NNS
cord-022561-rv5j1201	1210	5	are	be	VBP
cord-022561-rv5j1201	1210	6	found	find	VBN
cord-022561-rv5j1201	1210	7	in	in	IN
cord-022561-rv5j1201	1210	8	high	high	JJ
cord-022561-rv5j1201	1210	9	numbers	number	NNS
cord-022561-rv5j1201	1210	10	in	in	IN
cord-022561-rv5j1201	1210	11	the	the	DT
cord-022561-rv5j1201	1210	12	bone	bone	NN
cord-022561-rv5j1201	1210	13	marrow	marrow	NN
cord-022561-rv5j1201	1210	14	and	and	CC
cord-022561-rv5j1201	1210	15	commonly	commonly	RB
cord-022561-rv5j1201	1210	16	in	in	IN
cord-022561-rv5j1201	1210	17	other	other	JJ
cord-022561-rv5j1201	1210	18	tissues	tissue	NNS
cord-022561-rv5j1201	1210	19	,	,	,
cord-022561-rv5j1201	1210	20	including	include	VBG
cord-022561-rv5j1201	1210	21	lymph	lymph	NN
cord-022561-rv5j1201	1210	22	nodes	node	NNS
cord-022561-rv5j1201	1210	23	,	,	,
cord-022561-rv5j1201	1210	24	spleen	spleen	NNS
cord-022561-rv5j1201	1210	25	,	,	,
cord-022561-rv5j1201	1210	26	and	and	CC
cord-022561-rv5j1201	1210	27	liver	liver	NN
cord-022561-rv5j1201	1210	28	.	.	.
cord-022561-rv5j1201	1211	1	Additional	additional	JJ
cord-022561-rv5j1201	1211	2	bone	bone	NN
cord-022561-rv5j1201	1211	3	marrow	marrow	NN
cord-022561-rv5j1201	1211	4	findings	finding	NNS
cord-022561-rv5j1201	1211	5	reported	report	VBN
cord-022561-rv5j1201	1211	6	in	in	IN
cord-022561-rv5j1201	1211	7	animals	animal	NNS
cord-022561-rv5j1201	1211	8	with	with	IN
cord-022561-rv5j1201	1211	9	hemophagocytic	hemophagocytic	JJ
cord-022561-rv5j1201	1211	10	syndrome	syndrome	NN
cord-022561-rv5j1201	1211	11	vary	vary	VBP
cord-022561-rv5j1201	1211	12	widely	widely	RB
cord-022561-rv5j1201	1211	13	,	,	,
cord-022561-rv5j1201	1211	14	ranging	range	VBG
cord-022561-rv5j1201	1211	15	from	from	IN
cord-022561-rv5j1201	1211	16	hypoplasia	hypoplasia	NN
cord-022561-rv5j1201	1211	17	to	to	IN
cord-022561-rv5j1201	1211	18	hyperplasia	hyperplasia	NN
cord-022561-rv5j1201	1211	19	of	of	IN
cord-022561-rv5j1201	1211	20	cell	cell	NN
cord-022561-rv5j1201	1211	21	lines	line	NNS
cord-022561-rv5j1201	1211	22	with	with	IN
cord-022561-rv5j1201	1211	23	peripheral	peripheral	JJ
cord-022561-rv5j1201	1211	24	cytopenias	cytopenia	NNS
cord-022561-rv5j1201	1211	25	.	.	.
cord-022561-rv5j1201	1212	1	Disseminated	disseminate	VBN
cord-022561-rv5j1201	1212	2	Intravascular	Intravascular	NNP
cord-022561-rv5j1201	1212	3	Coagulation	Coagulation	NNP
cord-022561-rv5j1201	1212	4	.	.	.
cord-022561-rv5j1201	1213	1	Disseminated	disseminate	VBN
cord-022561-rv5j1201	1213	2	intravascular	intravascular	JJ
cord-022561-rv5j1201	1213	3	coagulation	coagulation	NN
cord-022561-rv5j1201	1213	4	is	be	VBZ
cord-022561-rv5j1201	1213	5	a	a	DT
cord-022561-rv5j1201	1213	6	syndrome	syndrome	NN
cord-022561-rv5j1201	1213	7	characterized	characterize	VBN
cord-022561-rv5j1201	1213	8	by	by	IN
cord-022561-rv5j1201	1213	9	continuous	continuous	JJ
cord-022561-rv5j1201	1213	10	activation	activation	NN
cord-022561-rv5j1201	1213	11	of	of	IN
cord-022561-rv5j1201	1213	12	both	both	DT
cord-022561-rv5j1201	1213	13	coagulation	coagulation	NN
cord-022561-rv5j1201	1213	14	and	and	CC
cord-022561-rv5j1201	1213	15	fibrinolytic	fibrinolytic	JJ
cord-022561-rv5j1201	1213	16	pathways	pathway	NNS
cord-022561-rv5j1201	1213	17	and	and	CC
cord-022561-rv5j1201	1213	18	is	be	VBZ
cord-022561-rv5j1201	1213	19	also	also	RB
cord-022561-rv5j1201	1213	20	known	know	VBN
cord-022561-rv5j1201	1213	21	as	as	IN
cord-022561-rv5j1201	1213	22	consumptive	consumptive	JJ
cord-022561-rv5j1201	1213	23	coagulopathy	coagulopathy	NN
cord-022561-rv5j1201	1213	24	.	.	.
cord-022561-rv5j1201	1214	1	It	-PRON-	PRP
cord-022561-rv5j1201	1214	2	is	be	VBZ
cord-022561-rv5j1201	1214	3	not	not	RB
cord-022561-rv5j1201	1214	4	a	a	DT
cord-022561-rv5j1201	1214	5	primary	primary	JJ
cord-022561-rv5j1201	1214	6	disease	disease	NN
cord-022561-rv5j1201	1214	7	,	,	,
cord-022561-rv5j1201	1214	8	but	but	CC
cord-022561-rv5j1201	1214	9	754.e1	754.e1	CD
cord-022561-rv5j1201	1214	10	CHAPTER	chapter	NN
cord-022561-rv5j1201	1214	11	13	13	CD
cord-022561-rv5j1201	1214	12	Bone	Bone	NNP
cord-022561-rv5j1201	1214	13	Marrow	Marrow	NNP
cord-022561-rv5j1201	1214	14	,	,	,
cord-022561-rv5j1201	1214	15	Blood	blood	NN
cord-022561-rv5j1201	1214	16	Cells	cell	NNS
cord-022561-rv5j1201	1214	17	,	,	,
cord-022561-rv5j1201	1214	18	and	and	CC
cord-022561-rv5j1201	1214	19	the	the	DT
cord-022561-rv5j1201	1214	20	Lymphoid	Lymphoid	NNP
cord-022561-rv5j1201	1214	21	/	/	SYM
cord-022561-rv5j1201	1214	22	Lymphatic	Lymphatic	NNP
cord-022561-rv5j1201	1214	23	System	System	NNP
cord-022561-rv5j1201	1214	24	Disseminated	disseminate	VBD
cord-022561-rv5j1201	1214	25	intravascular	intravascular	JJ
cord-022561-rv5j1201	1214	26	coagulation	coagulation	NN
cord-022561-rv5j1201	1214	27	is	be	VBZ
cord-022561-rv5j1201	1214	28	a	a	DT
cord-022561-rv5j1201	1214	29	consumptive	consumptive	JJ
cord-022561-rv5j1201	1214	30	coagulopathy	coagulopathy	NN
cord-022561-rv5j1201	1214	31	resulting	result	VBG
cord-022561-rv5j1201	1214	32	from	from	IN
cord-022561-rv5j1201	1214	33	activation	activation	NN
cord-022561-rv5j1201	1214	34	of	of	IN
cord-022561-rv5j1201	1214	35	both	both	DT
cord-022561-rv5j1201	1214	36	coagulation	coagulation	NN
cord-022561-rv5j1201	1214	37	and	and	CC
cord-022561-rv5j1201	1214	38	fibrinolytic	fibrinolytic	JJ
cord-022561-rv5j1201	1214	39	pathways	pathway	NNS
cord-022561-rv5j1201	1214	40	.	.	.
cord-022561-rv5j1201	1215	1	It	-PRON-	PRP
cord-022561-rv5j1201	1215	2	is	be	VBZ
cord-022561-rv5j1201	1215	3	a	a	DT
cord-022561-rv5j1201	1215	4	secondary	secondary	JJ
cord-022561-rv5j1201	1215	5	complication	complication	NN
cord-022561-rv5j1201	1215	6	of	of	IN
cord-022561-rv5j1201	1215	7	many	many	JJ
cord-022561-rv5j1201	1215	8	types	type	NNS
cord-022561-rv5j1201	1215	9	of	of	IN
cord-022561-rv5j1201	1215	10	underlying	underlie	VBG
cord-022561-rv5j1201	1215	11	disease	disease	NN
cord-022561-rv5j1201	1215	12	,	,	,
cord-022561-rv5j1201	1215	13	including	include	VBG
cord-022561-rv5j1201	1215	14	many	many	JJ
cord-022561-rv5j1201	1215	15	infectious	infectious	JJ
cord-022561-rv5j1201	1215	16	diseases	disease	NNS
cord-022561-rv5j1201	1215	17	,	,	,
cord-022561-rv5j1201	1215	18	trauma	trauma	NN
cord-022561-rv5j1201	1215	19	,	,	,
cord-022561-rv5j1201	1215	20	burns	burn	NNS
cord-022561-rv5j1201	1215	21	,	,	,
cord-022561-rv5j1201	1215	22	heat	heat	NN
cord-022561-rv5j1201	1215	23	stroke	stroke	NN
cord-022561-rv5j1201	1215	24	,	,	,
cord-022561-rv5j1201	1215	25	immune	immune	NN
cord-022561-rv5j1201	1215	26	-	-	HYPH
cord-022561-rv5j1201	1215	27	mediated	mediate	VBN
cord-022561-rv5j1201	1215	28	disease	disease	NN
cord-022561-rv5j1201	1215	29	,	,	,
cord-022561-rv5j1201	1215	30	hemolysis	hemolysis	NN
cord-022561-rv5j1201	1215	31	,	,	,
cord-022561-rv5j1201	1215	32	shock	shock	NN
cord-022561-rv5j1201	1215	33	,	,	,
cord-022561-rv5j1201	1215	34	neoplasia	neoplasia	NN
cord-022561-rv5j1201	1215	35	,	,	,
cord-022561-rv5j1201	1215	36	organ	organ	NN
cord-022561-rv5j1201	1215	37	failure	failure	NN
cord-022561-rv5j1201	1215	38	,	,	,
cord-022561-rv5j1201	1215	39	obstetric	obstetric	JJ
cord-022561-rv5j1201	1215	40	complications	complication	NNS
cord-022561-rv5j1201	1215	41	,	,	,
cord-022561-rv5j1201	1215	42	and	and	CC
cord-022561-rv5j1201	1215	43	noninfectious	noninfectious	JJ
cord-022561-rv5j1201	1215	44	inflammatory	inflammatory	JJ
cord-022561-rv5j1201	1215	45	disease	disease	NN
cord-022561-rv5j1201	1215	46	,	,	,
cord-022561-rv5j1201	1215	47	such	such	JJ
cord-022561-rv5j1201	1215	48	as	as	IN
cord-022561-rv5j1201	1215	49	pancreatitis	pancreatitis	NN
cord-022561-rv5j1201	1215	50	.	.	.
cord-022561-rv5j1201	1216	1	It	-PRON-	PRP
cord-022561-rv5j1201	1216	2	is	be	VBZ
cord-022561-rv5j1201	1216	3	common	common	JJ
cord-022561-rv5j1201	1216	4	in	in	IN
cord-022561-rv5j1201	1216	5	critically	critically	RB
cord-022561-rv5j1201	1216	6	ill	ill	JJ
cord-022561-rv5j1201	1216	7	domestic	domestic	JJ
cord-022561-rv5j1201	1216	8	animals	animal	NNS
cord-022561-rv5j1201	1216	9	.	.	.
cord-022561-rv5j1201	1217	1	Disseminated	disseminate	VBN
cord-022561-rv5j1201	1217	2	intravascular	intravascular	JJ
cord-022561-rv5j1201	1217	3	coagulation	coagulation	NN
cord-022561-rv5j1201	1217	4	involves	involve	VBZ
cord-022561-rv5j1201	1217	5	an	an	DT
cord-022561-rv5j1201	1217	6	initial	initial	JJ
cord-022561-rv5j1201	1217	7	hypercoagulable	hypercoagulable	JJ
cord-022561-rv5j1201	1217	8	phase	phase	NN
cord-022561-rv5j1201	1217	9	,	,	,
cord-022561-rv5j1201	1217	10	resulting	result	VBG
cord-022561-rv5j1201	1217	11	in	in	IN
cord-022561-rv5j1201	1217	12	thrombosis	thrombosis	NN
cord-022561-rv5j1201	1217	13	and	and	CC
cord-022561-rv5j1201	1217	14	ischemic	ischemic	JJ
cord-022561-rv5j1201	1217	15	tissue	tissue	NN
cord-022561-rv5j1201	1217	16	damage	damage	NN
cord-022561-rv5j1201	1217	17	,	,	,
cord-022561-rv5j1201	1217	18	and	and	CC
cord-022561-rv5j1201	1217	19	a	a	DT
cord-022561-rv5j1201	1217	20	subsequent	subsequent	JJ
cord-022561-rv5j1201	1217	21	hypocoagulable	hypocoagulable	NN
cord-022561-rv5j1201	1217	22	phase	phase	NN
cord-022561-rv5j1201	1217	23	as	as	IN
cord-022561-rv5j1201	1217	24	a	a	DT
cord-022561-rv5j1201	1217	25	result	result	NN
cord-022561-rv5j1201	1217	26	of	of	IN
cord-022561-rv5j1201	1217	27	consumption	consumption	NN
cord-022561-rv5j1201	1217	28	of	of	IN
cord-022561-rv5j1201	1217	29	coagulation	coagulation	NN
cord-022561-rv5j1201	1217	30	factors	factor	NNS
cord-022561-rv5j1201	1217	31	and	and	CC
cord-022561-rv5j1201	1217	32	platelets	platelet	NNS
cord-022561-rv5j1201	1217	33	,	,	,
cord-022561-rv5j1201	1217	34	resulting	result	VBG
cord-022561-rv5j1201	1217	35	in	in	IN
cord-022561-rv5j1201	1217	36	hemorrhage	hemorrhage	NN
cord-022561-rv5j1201	1217	37	(	(	-LRB-
cord-022561-rv5j1201	1217	38	E-	E-	NNP
cord-022561-rv5j1201	1217	39	Fig	Fig	NNP
cord-022561-rv5j1201	1217	40	.	.	.
cord-022561-rv5j1201	1218	1	13	13	CD
cord-022561-rv5j1201	1218	2	-	-	SYM
cord-022561-rv5j1201	1218	3	5	5	CD
cord-022561-rv5j1201	1218	4	)	)	-RRB-
cord-022561-rv5j1201	1218	5	.	.	.
cord-022561-rv5j1201	1219	1	The	the	DT
cord-022561-rv5j1201	1219	2	pathogenesis	pathogenesis	NN
cord-022561-rv5j1201	1219	3	of	of	IN
cord-022561-rv5j1201	1219	4	disseminated	disseminate	VBN
cord-022561-rv5j1201	1219	5	intravascular	intravascular	JJ
cord-022561-rv5j1201	1219	6	coagulation	coagulation	NN
cord-022561-rv5j1201	1219	7	typically	typically	RB
cord-022561-rv5j1201	1219	8	involves	involve	VBZ
cord-022561-rv5j1201	1219	9	the	the	DT
cord-022561-rv5j1201	1219	10	release	release	NN
cord-022561-rv5j1201	1219	11	of	of	IN
cord-022561-rv5j1201	1219	12	tissue	tissue	NN
cord-022561-rv5j1201	1219	13	factor	factor	NN
cord-022561-rv5j1201	1219	14	(	(	-LRB-
cord-022561-rv5j1201	1219	15	thromboplastin	thromboplastin	NNP
cord-022561-rv5j1201	1219	16	)	)	-RRB-
cord-022561-rv5j1201	1219	17	and	and	CC
cord-022561-rv5j1201	1219	18	subsequent	subsequent	JJ
cord-022561-rv5j1201	1219	19	activation	activation	NN
cord-022561-rv5j1201	1219	20	of	of	IN
cord-022561-rv5j1201	1219	21	coagulation	coagulation	NN
cord-022561-rv5j1201	1219	22	pathways	pathway	NNS
cord-022561-rv5j1201	1219	23	and	and	CC
cord-022561-rv5j1201	1219	24	platelets	platelet	NNS
cord-022561-rv5j1201	1219	25	but	but	CC
cord-022561-rv5j1201	1219	26	may	may	MD
cord-022561-rv5j1201	1219	27	also	also	RB
cord-022561-rv5j1201	1219	28	involve	involve	VB
cord-022561-rv5j1201	1219	29	defective	defective	JJ
cord-022561-rv5j1201	1219	30	normal	normal	JJ
cord-022561-rv5j1201	1219	31	inhibition	inhibition	NN
cord-022561-rv5j1201	1219	32	of	of	IN
cord-022561-rv5j1201	1219	33	coagulation	coagulation	NN
cord-022561-rv5j1201	1219	34	or	or	CC
cord-022561-rv5j1201	1219	35	defective	defective	JJ
cord-022561-rv5j1201	1219	36	fibrinolysis	fibrinolysis	NN
cord-022561-rv5j1201	1219	37	.	.	.
cord-022561-rv5j1201	1220	1	Classically	classically	RB
cord-022561-rv5j1201	1220	2	diagnosis	diagnosis	NN
cord-022561-rv5j1201	1220	3	of	of	IN
cord-022561-rv5j1201	1220	4	disseminated	disseminate	VBN
cord-022561-rv5j1201	1220	5	intravascular	intravascular	JJ
cord-022561-rv5j1201	1220	6	coagulation	coagulation	NN
cord-022561-rv5j1201	1220	7	is	be	VBZ
cord-022561-rv5j1201	1220	8	based	base	VBN
cord-022561-rv5j1201	1220	9	on	on	IN
cord-022561-rv5j1201	1220	10	clinical	clinical	JJ
cord-022561-rv5j1201	1220	11	evidence	evidence	NN
cord-022561-rv5j1201	1220	12	of	of	IN
cord-022561-rv5j1201	1220	13	hemorrhage	hemorrhage	NN
cord-022561-rv5j1201	1220	14	and/or	and/or	CC
cord-022561-rv5j1201	1220	15	thromboembolic	thromboembolic	JJ
cord-022561-rv5j1201	1220	16	disease	disease	NN
cord-022561-rv5j1201	1220	17	and	and	CC
cord-022561-rv5j1201	1220	18	a	a	DT
cord-022561-rv5j1201	1220	19	triad	triad	NN
cord-022561-rv5j1201	1220	20	of	of	IN
cord-022561-rv5j1201	1220	21	laboratory	laboratory	NN
cord-022561-rv5j1201	1220	22	findings	finding	NNS
cord-022561-rv5j1201	1220	23	:	:	:
cord-022561-rv5j1201	1220	24	thrombocytopenia	thrombocytopenia	NN
cord-022561-rv5j1201	1220	25	,	,	,
cord-022561-rv5j1201	1220	26	usually	usually	RB
cord-022561-rv5j1201	1220	27	moderate	moderate	VBP
cord-022561-rv5j1201	1220	28	(	(	-LRB-
cord-022561-rv5j1201	1220	29	below	below	IN
cord-022561-rv5j1201	1220	30	the	the	DT
cord-022561-rv5j1201	1220	31	lower	low	JJR
cord-022561-rv5j1201	1220	32	reference	reference	NN
cord-022561-rv5j1201	1220	33	value	value	NN
cord-022561-rv5j1201	1220	34	but	but	CC
cord-022561-rv5j1201	1220	35	above	above	IN
cord-022561-rv5j1201	1220	36	50,000/µL	50,000/µl	CD
cord-022561-rv5j1201	1220	37	)	)	-RRB-
cord-022561-rv5j1201	1220	38	;	;	,
cord-022561-rv5j1201	1220	39	prolonged	prolonged	JJ
cord-022561-rv5j1201	1220	40	coagulation	coagulation	NN
cord-022561-rv5j1201	1220	41	times	time	NNS
cord-022561-rv5j1201	1220	42	(	(	-LRB-
cord-022561-rv5j1201	1220	43	prothrombin	prothrombin	NN
cord-022561-rv5j1201	1220	44	time	time	NN
cord-022561-rv5j1201	1220	45	and/or	and/or	CC
cord-022561-rv5j1201	1220	46	partial	partial	JJ
cord-022561-rv5j1201	1220	47	thromboplastin	thromboplastin	NNP
cord-022561-rv5j1201	1220	48	time	time	NN
cord-022561-rv5j1201	1220	49	)	)	-RRB-
cord-022561-rv5j1201	1220	50	;	;	:
cord-022561-rv5j1201	1220	51	and	and	CC
cord-022561-rv5j1201	1220	52	decreased	decrease	VBD
cord-022561-rv5j1201	1220	53	fibrinogen	fibrinogen	NN
cord-022561-rv5j1201	1220	54	or	or	CC
cord-022561-rv5j1201	1220	55	increased	increase	VBN
cord-022561-rv5j1201	1220	56	concentration	concentration	NN
cord-022561-rv5j1201	1220	57	of	of	IN
cord-022561-rv5j1201	1220	58	plasma	plasma	NN
cord-022561-rv5j1201	1220	59	fibrin	fibrin	NN
cord-022561-rv5j1201	1220	60	degradation	degradation	NN
cord-022561-rv5j1201	1220	61	products	product	NNS
cord-022561-rv5j1201	1220	62	or	or	CC
cord-022561-rv5j1201	1220	63	D	d	NN
cord-022561-rv5j1201	1220	64	-	-	HYPH
cord-022561-rv5j1201	1220	65	dimer	dimer	NN
cord-022561-rv5j1201	1220	66	.	.	.
cord-022561-rv5j1201	1221	1	Milder	mild	JJR
cord-022561-rv5j1201	1221	2	forms	form	NNS
cord-022561-rv5j1201	1221	3	of	of	IN
cord-022561-rv5j1201	1221	4	disseminated	disseminate	VBN
cord-022561-rv5j1201	1221	5	intravascular	intravascular	JJ
cord-022561-rv5j1201	1221	6	coagulation	coagulation	NN
cord-022561-rv5j1201	1221	7	that	that	WDT
cord-022561-rv5j1201	1221	8	do	do	VBP
cord-022561-rv5j1201	1221	9	not	not	RB
cord-022561-rv5j1201	1221	10	meet	meet	VB
cord-022561-rv5j1201	1221	11	all	all	DT
cord-022561-rv5j1201	1221	12	of	of	IN
cord-022561-rv5j1201	1221	13	the	the	DT
cord-022561-rv5j1201	1221	14	diagnostic	diagnostic	JJ
cord-022561-rv5j1201	1221	15	criteria	criterion	NNS
cord-022561-rv5j1201	1221	16	also	also	RB
cord-022561-rv5j1201	1221	17	occur	occur	VBP
cord-022561-rv5j1201	1221	18	.	.	.
cord-022561-rv5j1201	1222	1	Decreased	decrease	VBN
cord-022561-rv5j1201	1223	1	plasma	plasma	NNP
cord-022561-rv5j1201	1223	2	antithrombin	antithrombin	NNP
cord-022561-rv5j1201	1223	3	(	(	-LRB-
cord-022561-rv5j1201	1223	4	antithrombin	antithrombin	NN
cord-022561-rv5j1201	1223	5	III	III	NNP
cord-022561-rv5j1201	1223	6	)	)	-RRB-
cord-022561-rv5j1201	1223	7	concentration	concentration	NN
cord-022561-rv5j1201	1223	8	and	and	CC
cord-022561-rv5j1201	1223	9	schistocytosis	schistocytosis	NN
cord-022561-rv5j1201	1223	10	are	be	VBP
cord-022561-rv5j1201	1223	11	other	other	JJ
cord-022561-rv5j1201	1223	12	laboratory	laboratory	NN
cord-022561-rv5j1201	1223	13	abnormalities	abnormality	NNS
cord-022561-rv5j1201	1223	14	often	often	RB
cord-022561-rv5j1201	1223	15	found	find	VBD
cord-022561-rv5j1201	1223	16	in	in	IN
cord-022561-rv5j1201	1223	17	patients	patient	NNS
cord-022561-rv5j1201	1223	18	with	with	IN
cord-022561-rv5j1201	1223	19	disseminated	disseminate	VBN
cord-022561-rv5j1201	1223	20	intravascular	intravascular	JJ
cord-022561-rv5j1201	1223	21	coagulation	coagulation	NN
cord-022561-rv5j1201	1223	22	.	.	.
cord-022561-rv5j1201	1224	1	dysplasia	dysplasia	NN
cord-022561-rv5j1201	1224	2	of	of	IN
cord-022561-rv5j1201	1224	3	myeloid	myeloid	NN
cord-022561-rv5j1201	1224	4	cells	cell	NNS
cord-022561-rv5j1201	1224	5	,	,	,
cord-022561-rv5j1201	1224	6	and	and	CC
cord-022561-rv5j1201	1224	7	fewer	few	JJR
cord-022561-rv5j1201	1224	8	than	than	IN
cord-022561-rv5j1201	1224	9	20	20	CD
cord-022561-rv5j1201	1224	10	%	%	NN
cord-022561-rv5j1201	1224	11	myeloblasts	myeloblast	NNS
cord-022561-rv5j1201	1224	12	and	and	CC
cord-022561-rv5j1201	1224	13	"	"	``
cord-022561-rv5j1201	1224	14	blast	blast	NN
cord-022561-rv5j1201	1224	15	equivalents	equivalent	NNS
cord-022561-rv5j1201	1224	16	.	.	.
cord-022561-rv5j1201	1225	1	"	"	``
cord-022561-rv5j1201	1225	2	3	3	CD
cord-022561-rv5j1201	1225	3	Acute	Acute	NNP
cord-022561-rv5j1201	1225	4	Myeloid	Myeloid	NNP
cord-022561-rv5j1201	1225	5	Leukemia	Leukemia	NNP
cord-022561-rv5j1201	1225	6	.	.	.
cord-022561-rv5j1201	1226	1	Acute	acute	JJ
cord-022561-rv5j1201	1226	2	myeloid	myeloid	NN
cord-022561-rv5j1201	1226	3	leukemia	leukemia	NN
cord-022561-rv5j1201	1226	4	(	(	-LRB-
cord-022561-rv5j1201	1226	5	AML	AML	NNP
cord-022561-rv5j1201	1226	6	)	)	-RRB-
cord-022561-rv5j1201	1226	7	is	be	VBZ
cord-022561-rv5j1201	1226	8	uncommon	uncommon	JJ
cord-022561-rv5j1201	1226	9	in	in	IN
cord-022561-rv5j1201	1226	10	domestic	domestic	JJ
cord-022561-rv5j1201	1226	11	animals	animal	NNS
cord-022561-rv5j1201	1226	12	but	but	CC
cord-022561-rv5j1201	1226	13	most	most	RBS
cord-022561-rv5j1201	1226	14	frequently	frequently	RB
cord-022561-rv5j1201	1226	15	occurs	occur	VBZ
cord-022561-rv5j1201	1226	16	in	in	IN
cord-022561-rv5j1201	1226	17	dogs	dog	NNS
cord-022561-rv5j1201	1226	18	and	and	CC
cord-022561-rv5j1201	1226	19	cats	cat	NNS
cord-022561-rv5j1201	1226	20	.	.	.
cord-022561-rv5j1201	1227	1	In	in	IN
cord-022561-rv5j1201	1227	2	veterinary	veterinary	JJ
cord-022561-rv5j1201	1227	3	species	specie	NNS
cord-022561-rv5j1201	1227	4	,	,	,
cord-022561-rv5j1201	1227	5	acute	acute	JJ
cord-022561-rv5j1201	1227	6	myeloid	myeloid	NN
cord-022561-rv5j1201	1227	7	leukemia	leukemia	NN
cord-022561-rv5j1201	1227	8	is	be	VBZ
cord-022561-rv5j1201	1227	9	most	most	RBS
cord-022561-rv5j1201	1227	10	commonly	commonly	RB
cord-022561-rv5j1201	1227	11	of	of	IN
cord-022561-rv5j1201	1227	12	neutrophil	neutrophil	NN
cord-022561-rv5j1201	1227	13	,	,	,
cord-022561-rv5j1201	1227	14	monocyte	monocyte	NNP
cord-022561-rv5j1201	1227	15	,	,	,
cord-022561-rv5j1201	1227	16	and/or	and/or	CC
cord-022561-rv5j1201	1227	17	erythroid	erythroid	JJ
cord-022561-rv5j1201	1227	18	origin	origin	NN
cord-022561-rv5j1201	1227	19	,	,	,
cord-022561-rv5j1201	1227	20	with	with	IN
cord-022561-rv5j1201	1227	21	rare	rare	JJ
cord-022561-rv5j1201	1227	22	reports	report	NNS
cord-022561-rv5j1201	1227	23	of	of	IN
cord-022561-rv5j1201	1227	24	eosinophil	eosinophil	NNP
cord-022561-rv5j1201	1227	25	,	,	,
cord-022561-rv5j1201	1227	26	basophil	basophil	NNP
cord-022561-rv5j1201	1227	27	,	,	,
cord-022561-rv5j1201	1227	28	or	or	CC
cord-022561-rv5j1201	1227	29	megakaryocytic	megakaryocytic	JJ
cord-022561-rv5j1201	1227	30	lineages	lineage	NNS
cord-022561-rv5j1201	1227	31	.	.	.
cord-022561-rv5j1201	1228	1	It	-PRON-	PRP
cord-022561-rv5j1201	1228	2	is	be	VBZ
cord-022561-rv5j1201	1228	3	caused	cause	VBN
cord-022561-rv5j1201	1228	4	by	by	IN
cord-022561-rv5j1201	1228	5	FeLV	FeLV	NNP
cord-022561-rv5j1201	1228	6	infection	infection	NN
cord-022561-rv5j1201	1228	7	in	in	IN
cord-022561-rv5j1201	1228	8	cats	cat	NNS
cord-022561-rv5j1201	1228	9	.	.	.
cord-022561-rv5j1201	1229	1	Evaluations	evaluation	NNS
cord-022561-rv5j1201	1229	2	of	of	IN
cord-022561-rv5j1201	1229	3	blood	blood	NN
cord-022561-rv5j1201	1229	4	smears	smear	NNS
cord-022561-rv5j1201	1229	5	show	show	VBP
cord-022561-rv5j1201	1229	6	many	many	JJ
cord-022561-rv5j1201	1229	7	early	early	JJ
cord-022561-rv5j1201	1229	8	myeloid	myeloid	JJ
cord-022561-rv5j1201	1229	9	precursors	precursor	NNS
cord-022561-rv5j1201	1229	10	,	,	,
cord-022561-rv5j1201	1229	11	including	include	VBG
cord-022561-rv5j1201	1229	12	myeloblasts	myeloblast	NNS
cord-022561-rv5j1201	1229	13	and	and	CC
cord-022561-rv5j1201	1229	14	blast	blast	NN
cord-022561-rv5j1201	1229	15	equivalents	equivalent	NNS
cord-022561-rv5j1201	1229	16	(	(	-LRB-
cord-022561-rv5j1201	1229	17	Fig	Fig	NNP
cord-022561-rv5j1201	1229	18	.	.	NNP
cord-022561-rv5j1201	1229	19	13	13	CD
cord-022561-rv5j1201	1229	20	-	-	SYM
cord-022561-rv5j1201	1229	21	31	31	CD
cord-022561-rv5j1201	1229	22	,	,	,
cord-022561-rv5j1201	1229	23	A	A	NNP
cord-022561-rv5j1201	1229	24	)	)	-RRB-
cord-022561-rv5j1201	1229	25	.	.	.
cord-022561-rv5j1201	1230	1	In	in	IN
cord-022561-rv5j1201	1230	2	dogs	dog	NNS
cord-022561-rv5j1201	1230	3	the	the	DT
cord-022561-rv5j1201	1230	4	total	total	JJ
cord-022561-rv5j1201	1230	5	leukocyte	leukocyte	NN
cord-022561-rv5j1201	1230	6	concentration	concentration	NN
cord-022561-rv5j1201	1230	7	averages	average	VBZ
cord-022561-rv5j1201	1230	8	approximately	approximately	RB
cord-022561-rv5j1201	1230	9	70,000/µL	70,000/µl	CD
cord-022561-rv5j1201	1230	10	;	;	:
cord-022561-rv5j1201	1230	11	anemia	anemia	NN
cord-022561-rv5j1201	1230	12	,	,	,
cord-022561-rv5j1201	1230	13	neutropenia	neutropenia	NN
cord-022561-rv5j1201	1230	14	,	,	,
cord-022561-rv5j1201	1230	15	and	and	CC
cord-022561-rv5j1201	1230	16	thrombocytopenia	thrombocytopenia	NN
cord-022561-rv5j1201	1230	17	commonly	commonly	RB
cord-022561-rv5j1201	1230	18	occur	occur	VBP
cord-022561-rv5j1201	1230	19	.	.	.
cord-022561-rv5j1201	1231	1	Grossly	grossly	RB
cord-022561-rv5j1201	1231	2	,	,	,
cord-022561-rv5j1201	1231	3	animals	animal	NNS
cord-022561-rv5j1201	1231	4	show	show	VBP
cord-022561-rv5j1201	1231	5	lesions	lesion	NNS
cord-022561-rv5j1201	1231	6	attributed	attribute	VBN
cord-022561-rv5j1201	1231	7	to	to	IN
cord-022561-rv5j1201	1231	8	anemia	anemia	NN
cord-022561-rv5j1201	1231	9	,	,	,
cord-022561-rv5j1201	1231	10	neutropenia	neutropenia	NN
cord-022561-rv5j1201	1231	11	,	,	,
cord-022561-rv5j1201	1231	12	and	and	CC
cord-022561-rv5j1201	1231	13	thrombocytopenia	thrombocytopenia	NN
cord-022561-rv5j1201	1231	14	,	,	,
cord-022561-rv5j1201	1231	15	such	such	JJ
cord-022561-rv5j1201	1231	16	as	as	IN
cord-022561-rv5j1201	1231	17	pale	pale	JJ
cord-022561-rv5j1201	1231	18	mucous	mucous	JJ
cord-022561-rv5j1201	1231	19	membranes	membrane	NNS
cord-022561-rv5j1201	1231	20	,	,	,
cord-022561-rv5j1201	1231	21	secondary	secondary	JJ
cord-022561-rv5j1201	1231	22	infections	infection	NNS
cord-022561-rv5j1201	1231	23	,	,	,
cord-022561-rv5j1201	1231	24	and	and	CC
cord-022561-rv5j1201	1231	25	multisystemic	multisystemic	JJ
cord-022561-rv5j1201	1231	26	bleeding	bleeding	NN
cord-022561-rv5j1201	1231	27	,	,	,
cord-022561-rv5j1201	1231	28	respectively	respectively	RB
cord-022561-rv5j1201	1231	29	.	.	.
cord-022561-rv5j1201	1232	1	Neoplastic	neoplastic	JJ
cord-022561-rv5j1201	1232	2	cells	cell	NNS
cord-022561-rv5j1201	1232	3	often	often	RB
cord-022561-rv5j1201	1232	4	infiltrate	infiltrate	VBP
cord-022561-rv5j1201	1232	5	tissues	tissue	NNS
cord-022561-rv5j1201	1232	6	,	,	,
cord-022561-rv5j1201	1232	7	resulting	result	VBG
cord-022561-rv5j1201	1232	8	in	in	IN
cord-022561-rv5j1201	1232	9	splenomegaly	splenomegaly	NN
cord-022561-rv5j1201	1232	10	,	,	,
cord-022561-rv5j1201	1232	11	hepatomegaly	hepatomegaly	NNP
cord-022561-rv5j1201	1232	12	,	,	,
cord-022561-rv5j1201	1232	13	and	and	CC
cord-022561-rv5j1201	1232	14	lymphadenomegaly	lymphadenomegaly	NNP
cord-022561-rv5j1201	1232	15	.	.	.
cord-022561-rv5j1201	1233	1	Microscopically	microscopically	RB
cord-022561-rv5j1201	1233	2	,	,	,
cord-022561-rv5j1201	1233	3	myeloid	myeloid	NN
cord-022561-rv5j1201	1233	4	cells	cell	NNS
cord-022561-rv5j1201	1233	5	efface	efface	VBP
cord-022561-rv5j1201	1233	6	(	(	-LRB-
cord-022561-rv5j1201	1233	7	replace	replace	VB
cord-022561-rv5j1201	1233	8	)	)	-RRB-
cord-022561-rv5j1201	1233	9	the	the	DT
cord-022561-rv5j1201	1233	10	bone	bone	NN
cord-022561-rv5j1201	1233	11	marrow	marrow	NN
cord-022561-rv5j1201	1233	12	and	and	CC
cord-022561-rv5j1201	1233	13	infiltrate	infiltrate	VB
cord-022561-rv5j1201	1233	14	extramedullary	extramedullary	JJ
cord-022561-rv5j1201	1233	15	tissues	tissue	NNS
cord-022561-rv5j1201	1233	16	,	,	,
cord-022561-rv5j1201	1233	17	especially	especially	RB
cord-022561-rv5j1201	1233	18	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	1233	19	tissue	tissue	NN
cord-022561-rv5j1201	1233	20	.	.	.
cord-022561-rv5j1201	1234	1	Chronic	Chronic	NNP
cord-022561-rv5j1201	1234	2	Myeloid	Myeloid	NNP
cord-022561-rv5j1201	1234	3	Leukemia	Leukemia	NNP
cord-022561-rv5j1201	1234	4	.	.	.
cord-022561-rv5j1201	1235	1	Chronic	chronic	JJ
cord-022561-rv5j1201	1235	2	myeloid	myeloid	NN
cord-022561-rv5j1201	1235	3	leukemia	leukemia	NN
cord-022561-rv5j1201	1235	4	(	(	-LRB-
cord-022561-rv5j1201	1235	5	CML	CML	NNP
cord-022561-rv5j1201	1235	6	)	)	-RRB-
cord-022561-rv5j1201	1235	7	,	,	,
cord-022561-rv5j1201	1235	8	also	also	RB
cord-022561-rv5j1201	1235	9	called	call	VBN
cord-022561-rv5j1201	1235	10	chronic	chronic	JJ
cord-022561-rv5j1201	1235	11	myelogenous	myelogenous	NN
cord-022561-rv5j1201	1235	12	leukemia	leukemia	NN
cord-022561-rv5j1201	1235	13	or	or	CC
cord-022561-rv5j1201	1235	14	myeloproliferative	myeloproliferative	NNP
cord-022561-rv5j1201	1235	15	neoplasia	neoplasia	NN
cord-022561-rv5j1201	1235	16	,	,	,
cord-022561-rv5j1201	1235	17	is	be	VBZ
cord-022561-rv5j1201	1235	18	rare	rare	JJ
cord-022561-rv5j1201	1235	19	in	in	IN
cord-022561-rv5j1201	1235	20	animals	animal	NNS
cord-022561-rv5j1201	1235	21	.	.	.
cord-022561-rv5j1201	1236	1	Most	most	RBS
cord-022561-rv5j1201	1236	2	reported	report	VBN
cord-022561-rv5j1201	1236	3	cases	case	NNS
cord-022561-rv5j1201	1236	4	occur	occur	VBP
cord-022561-rv5j1201	1236	5	in	in	IN
cord-022561-rv5j1201	1236	6	dogs	dog	NNS
cord-022561-rv5j1201	1236	7	and	and	CC
cord-022561-rv5j1201	1236	8	cats	cat	NNS
cord-022561-rv5j1201	1236	9	.	.	.
cord-022561-rv5j1201	1237	1	There	there	EX
cord-022561-rv5j1201	1237	2	are	be	VBP
cord-022561-rv5j1201	1237	3	various	various	JJ
cord-022561-rv5j1201	1237	4	subclassifications	subclassification	NNS
cord-022561-rv5j1201	1237	5	of	of	IN
cord-022561-rv5j1201	1237	6	chronic	chronic	JJ
cord-022561-rv5j1201	1237	7	myeloid	myeloid	NN
cord-022561-rv5j1201	1237	8	leukemia	leukemia	NN
cord-022561-rv5j1201	1237	9	,	,	,
cord-022561-rv5j1201	1237	10	including	include	VBG
cord-022561-rv5j1201	1237	11	excessive	excessive	JJ
cord-022561-rv5j1201	1237	12	production	production	NN
cord-022561-rv5j1201	1237	13	of	of	IN
cord-022561-rv5j1201	1237	14	erythrocytes	erythrocyte	NNS
cord-022561-rv5j1201	1237	15	(	(	-LRB-
cord-022561-rv5j1201	1237	16	polycythemia	polycythemia	NN
cord-022561-rv5j1201	1237	17	vera	vera	NNP
cord-022561-rv5j1201	1237	18	)	)	-RRB-
cord-022561-rv5j1201	1237	19	,	,	,
cord-022561-rv5j1201	1237	20	platelets	platelet	NNS
cord-022561-rv5j1201	1237	21	(	(	-LRB-
cord-022561-rv5j1201	1237	22	essential	essential	JJ
cord-022561-rv5j1201	1237	23	thrombocythemia	thrombocythemia	NN
cord-022561-rv5j1201	1237	24	)	)	-RRB-
cord-022561-rv5j1201	1237	25	,	,	,
cord-022561-rv5j1201	1237	26	neutrophils	neutrophil	NNS
cord-022561-rv5j1201	1237	27	(	(	-LRB-
cord-022561-rv5j1201	1237	28	chronic	chronic	JJ
cord-022561-rv5j1201	1237	29	neutrophilic	neutrophilic	NNP
cord-022561-rv5j1201	1237	30	leukemia	leukemia	NN
cord-022561-rv5j1201	1237	31	)	)	-RRB-
cord-022561-rv5j1201	1237	32	,	,	,
cord-022561-rv5j1201	1237	33	monocytes	monocyte	NNS
cord-022561-rv5j1201	1237	34	(	(	-LRB-
cord-022561-rv5j1201	1237	35	chronic	chronic	JJ
cord-022561-rv5j1201	1237	36	monocytic	monocytic	JJ
cord-022561-rv5j1201	1237	37	leukemia	leukemia	NN
cord-022561-rv5j1201	1237	38	)	)	-RRB-
cord-022561-rv5j1201	1237	39	,	,	,
cord-022561-rv5j1201	1237	40	neutrophils	neutrophil	NNS
cord-022561-rv5j1201	1237	41	and	and	CC
cord-022561-rv5j1201	1237	42	monocytes	monocyte	NNS
cord-022561-rv5j1201	1237	43	(	(	-LRB-
cord-022561-rv5j1201	1237	44	chronic	chronic	JJ
cord-022561-rv5j1201	1237	45	myelomonocytic	myelomonocytic	NNP
cord-022561-rv5j1201	1237	46	leukemia	leukemia	NN
cord-022561-rv5j1201	1237	47	)	)	-RRB-
cord-022561-rv5j1201	1237	48	,	,	,
cord-022561-rv5j1201	1237	49	eosinophils	eosinophil	NNS
cord-022561-rv5j1201	1237	50	(	(	-LRB-
cord-022561-rv5j1201	1237	51	chronic	chronic	JJ
cord-022561-rv5j1201	1237	52	eosinophilic	eosinophilic	JJ
cord-022561-rv5j1201	1237	53	leukemia	leukemia	NN
cord-022561-rv5j1201	1237	54	)	)	-RRB-
cord-022561-rv5j1201	1237	55	,	,	,
cord-022561-rv5j1201	1237	56	or	or	CC
cord-022561-rv5j1201	1237	57	basophils	basophil	NNS
cord-022561-rv5j1201	1237	58	(	(	-LRB-
cord-022561-rv5j1201	1237	59	chronic	chronic	JJ
cord-022561-rv5j1201	1237	60	basophilic	basophilic	NN
cord-022561-rv5j1201	1237	61	leukemia	leukemia	NN
cord-022561-rv5j1201	1237	62	)	)	-RRB-
cord-022561-rv5j1201	1237	63	.	.	.
cord-022561-rv5j1201	1238	1	Complete	complete	JJ
cord-022561-rv5j1201	1238	2	peripheral	peripheral	JJ
cord-022561-rv5j1201	1238	3	blood	blood	NN
cord-022561-rv5j1201	1238	4	count	count	NN
cord-022561-rv5j1201	1238	5	analysis	analysis	NN
cord-022561-rv5j1201	1238	6	often	often	RB
cord-022561-rv5j1201	1238	7	reveals	reveal	VBZ
cord-022561-rv5j1201	1238	8	very	very	RB
cord-022561-rv5j1201	1238	9	high	high	JJ
cord-022561-rv5j1201	1238	10	concentrations	concentration	NNS
cord-022561-rv5j1201	1238	11	of	of	IN
cord-022561-rv5j1201	1238	12	the	the	DT
cord-022561-rv5j1201	1238	13	neoplastic	neoplastic	JJ
cord-022561-rv5j1201	1238	14	cells	cell	NNS
cord-022561-rv5j1201	1238	15	,	,	,
cord-022561-rv5j1201	1238	16	such	such	JJ
cord-022561-rv5j1201	1238	17	as	as	IN
cord-022561-rv5j1201	1238	18	greater	great	JJR
cord-022561-rv5j1201	1238	19	than	than	IN
cord-022561-rv5j1201	1238	20	50,000	50,000	CD
cord-022561-rv5j1201	1238	21	to	to	TO
cord-022561-rv5j1201	1238	22	100,000	100,000	CD
cord-022561-rv5j1201	1238	23	leukocytes/µL	leukocytes/µl	XX
cord-022561-rv5j1201	1238	24	(	(	-LRB-
cord-022561-rv5j1201	1238	25	see	see	VB
cord-022561-rv5j1201	1238	26	Fig	Fig	NNP
cord-022561-rv5j1201	1238	27	.	.	.
cord-022561-rv5j1201	1239	1	13	13	CD
cord-022561-rv5j1201	1239	2	-	-	SYM
cord-022561-rv5j1201	1239	3	31	31	CD
cord-022561-rv5j1201	1239	4	,	,	,
cord-022561-rv5j1201	1239	5	B	b	NN
cord-022561-rv5j1201	1239	6	)	)	-RRB-
cord-022561-rv5j1201	1239	7	or	or	CC
cord-022561-rv5j1201	1239	8	2,000,000	2,000,000	CD
cord-022561-rv5j1201	1239	9	platelets/µL.	platelets/µl.	NN
cord-022561-rv5j1201	1239	10	Cellular	cellular	JJ
cord-022561-rv5j1201	1239	11	morphologic	morphologic	JJ
cord-022561-rv5j1201	1239	12	features	feature	NNS
cord-022561-rv5j1201	1239	13	are	be	VBP
cord-022561-rv5j1201	1239	14	often	often	RB
cord-022561-rv5j1201	1239	15	normal	normal	JJ
cord-022561-rv5j1201	1239	16	,	,	,
cord-022561-rv5j1201	1239	17	but	but	CC
cord-022561-rv5j1201	1239	18	slight	slight	JJ
cord-022561-rv5j1201	1239	19	dysplasia	dysplasia	NN
cord-022561-rv5j1201	1239	20	may	may	MD
cord-022561-rv5j1201	1239	21	be	be	VB
cord-022561-rv5j1201	1239	22	observed	observe	VBN
cord-022561-rv5j1201	1239	23	.	.	.
cord-022561-rv5j1201	1240	1	Later	later	RB
cord-022561-rv5j1201	1240	2	in	in	IN
cord-022561-rv5j1201	1240	3	the	the	DT
cord-022561-rv5j1201	1240	4	disease	disease	NN
cord-022561-rv5j1201	1240	5	there	there	EX
cord-022561-rv5j1201	1240	6	may	may	MD
cord-022561-rv5j1201	1240	7	be	be	VB
cord-022561-rv5j1201	1240	8	cytopenias	cytopenia	NNS
cord-022561-rv5j1201	1240	9	of	of	IN
cord-022561-rv5j1201	1240	10	nonneoplastic	nonneoplastic	JJ
cord-022561-rv5j1201	1240	11	cell	cell	NN
cord-022561-rv5j1201	1240	12	types	type	NNS
cord-022561-rv5j1201	1240	13	.	.	.
cord-022561-rv5j1201	1241	1	Animals	animal	NNS
cord-022561-rv5j1201	1241	2	with	with	IN
cord-022561-rv5j1201	1241	3	polycythemia	polycythemia	NN
cord-022561-rv5j1201	1241	4	vera	vera	NN
cord-022561-rv5j1201	1241	5	often	often	RB
cord-022561-rv5j1201	1241	6	have	have	VBP
cord-022561-rv5j1201	1241	7	red	red	JJ
cord-022561-rv5j1201	1241	8	mucous	mucous	JJ
cord-022561-rv5j1201	1241	9	membranes	membrane	NNS
cord-022561-rv5j1201	1241	10	and	and	CC
cord-022561-rv5j1201	1241	11	lesions	lesion	NNS
cord-022561-rv5j1201	1241	12	of	of	IN
cord-022561-rv5j1201	1241	13	hyperviscosity	hyperviscosity	NN
cord-022561-rv5j1201	1241	14	syndrome	syndrome	NN
cord-022561-rv5j1201	1241	15	,	,	,
cord-022561-rv5j1201	1241	16	such	such	JJ
cord-022561-rv5j1201	1241	17	as	as	IN
cord-022561-rv5j1201	1241	18	bleeding	bleed	VBG
cord-022561-rv5j1201	1241	19	and	and	CC
cord-022561-rv5j1201	1241	20	dilated	dilated	JJ
cord-022561-rv5j1201	1241	21	,	,	,
cord-022561-rv5j1201	1241	22	tortuous	tortuous	JJ
cord-022561-rv5j1201	1241	23	retinal	retinal	JJ
cord-022561-rv5j1201	1241	24	vessels	vessel	NNS
cord-022561-rv5j1201	1241	25	.	.	.
cord-022561-rv5j1201	1242	1	Essential	essential	JJ
cord-022561-rv5j1201	1242	2	thrombocythemia	thrombocythemia	NN
cord-022561-rv5j1201	1242	3	results	result	VBZ
cord-022561-rv5j1201	1242	4	in	in	IN
cord-022561-rv5j1201	1242	5	multisystemic	multisystemic	JJ
cord-022561-rv5j1201	1242	6	bleeding	bleed	VBG
cord-022561-rv5j1201	1242	7	due	due	IN
cord-022561-rv5j1201	1242	8	to	to	IN
cord-022561-rv5j1201	1242	9	dysfunctional	dysfunctional	JJ
cord-022561-rv5j1201	1242	10	platelets	platelet	NNS
cord-022561-rv5j1201	1242	11	,	,	,
cord-022561-rv5j1201	1242	12	or	or	CC
cord-022561-rv5j1201	1242	13	multisystemic	multisystemic	JJ
cord-022561-rv5j1201	1242	14	infarcts	infarct	NNS
cord-022561-rv5j1201	1242	15	from	from	IN
cord-022561-rv5j1201	1242	16	hyperaggregability	hyperaggregability	NN
cord-022561-rv5j1201	1242	17	and	and	CC
cord-022561-rv5j1201	1242	18	excessive	excessive	JJ
cord-022561-rv5j1201	1242	19	platelets	platelet	NNS
cord-022561-rv5j1201	1242	20	.	.	.
cord-022561-rv5j1201	1243	1	Chronic	chronic	JJ
cord-022561-rv5j1201	1243	2	myeloid	myeloid	NN
cord-022561-rv5j1201	1243	3	leukemias	leukemia	NNS
cord-022561-rv5j1201	1243	4	of	of	IN
cord-022561-rv5j1201	1243	5	leukocytes	leukocyte	NNS
cord-022561-rv5j1201	1243	6	often	often	RB
cord-022561-rv5j1201	1243	7	result	result	VBP
cord-022561-rv5j1201	1243	8	in	in	IN
cord-022561-rv5j1201	1243	9	splenomegaly	splenomegaly	NN
cord-022561-rv5j1201	1243	10	,	,	,
cord-022561-rv5j1201	1243	11	hepatomegaly	hepatomegaly	NNP
cord-022561-rv5j1201	1243	12	,	,	,
cord-022561-rv5j1201	1243	13	and	and	CC
cord-022561-rv5j1201	1243	14	lymphadenomegaly	lymphadenomegaly	NNP
cord-022561-rv5j1201	1243	15	because	because	IN
cord-022561-rv5j1201	1243	16	of	of	IN
cord-022561-rv5j1201	1243	17	infiltration	infiltration	NN
cord-022561-rv5j1201	1243	18	by	by	IN
cord-022561-rv5j1201	1243	19	the	the	DT
cord-022561-rv5j1201	1243	20	neoplastic	neoplastic	JJ
cord-022561-rv5j1201	1243	21	cells	cell	NNS
cord-022561-rv5j1201	1243	22	.	.	.
cord-022561-rv5j1201	1244	1	Histologically	histologically	RB
cord-022561-rv5j1201	1244	2	,	,	,
cord-022561-rv5j1201	1244	3	the	the	DT
cord-022561-rv5j1201	1244	4	bone	bone	NN
cord-022561-rv5j1201	1244	5	marrow	marrow	NN
cord-022561-rv5j1201	1244	6	shows	show	VBZ
cord-022561-rv5j1201	1244	7	proliferation	proliferation	NN
cord-022561-rv5j1201	1244	8	of	of	IN
cord-022561-rv5j1201	1244	9	the	the	DT
cord-022561-rv5j1201	1244	10	neoplastic	neoplastic	JJ
cord-022561-rv5j1201	1244	11	cell	cell	NN
cord-022561-rv5j1201	1244	12	type	type	NN
cord-022561-rv5j1201	1244	13	characterized	characterize	VBN
cord-022561-rv5j1201	1244	14	by	by	IN
cord-022561-rv5j1201	1244	15	dysplasia	dysplasia	NN
cord-022561-rv5j1201	1244	16	and	and	CC
cord-022561-rv5j1201	1244	17	low	low	JJ
cord-022561-rv5j1201	1244	18	numbers	number	NNS
cord-022561-rv5j1201	1244	19	(	(	-LRB-
cord-022561-rv5j1201	1244	20	e.g.	e.g.	RB
cord-022561-rv5j1201	1244	21	,	,	,
cord-022561-rv5j1201	1244	22	<	<	XX
cord-022561-rv5j1201	1244	23	20	20	CD
cord-022561-rv5j1201	1244	24	%	%	NN
cord-022561-rv5j1201	1244	25	)	)	-RRB-
cord-022561-rv5j1201	1244	26	of	of	IN
cord-022561-rv5j1201	1244	27	myeloblasts	myeloblast	NNS
cord-022561-rv5j1201	1244	28	and	and	CC
cord-022561-rv5j1201	1244	29	blast	blast	NN
cord-022561-rv5j1201	1244	30	equivalents	equivalent	NNS
cord-022561-rv5j1201	1244	31	.	.	.
cord-022561-rv5j1201	1245	1	Mast	Mast	NNP
cord-022561-rv5j1201	1245	2	Cell	Cell	NNP
cord-022561-rv5j1201	1245	3	Neoplasia	Neoplasia	NNP
cord-022561-rv5j1201	1245	4	.	.	.
cord-022561-rv5j1201	1246	1	Mast	mast	JJ
cord-022561-rv5j1201	1246	2	cell	cell	NN
cord-022561-rv5j1201	1246	3	tumors	tumor	NNS
cord-022561-rv5j1201	1246	4	(	(	-LRB-
cord-022561-rv5j1201	1246	5	MCTs	MCTs	NNP
cord-022561-rv5j1201	1246	6	)	)	-RRB-
cord-022561-rv5j1201	1246	7	of	of	IN
cord-022561-rv5j1201	1246	8	the	the	DT
cord-022561-rv5j1201	1246	9	skin	skin	NN
cord-022561-rv5j1201	1246	10	and	and	CC
cord-022561-rv5j1201	1246	11	other	other	JJ
cord-022561-rv5j1201	1246	12	sites	site	NNS
cord-022561-rv5j1201	1246	13	are	be	VBP
cord-022561-rv5j1201	1246	14	common	common	JJ
cord-022561-rv5j1201	1246	15	in	in	IN
cord-022561-rv5j1201	1246	16	animals	animal	NNS
cord-022561-rv5j1201	1246	17	(	(	-LRB-
cord-022561-rv5j1201	1246	18	see	see	VB
cord-022561-rv5j1201	1246	19	Chapters	Chapters	NNP
cord-022561-rv5j1201	1246	20	6	6	CD
cord-022561-rv5j1201	1246	21	,	,	,
cord-022561-rv5j1201	1246	22	7	7	CD
cord-022561-rv5j1201	1246	23	,	,	,
cord-022561-rv5j1201	1246	24	and	and	CC
cord-022561-rv5j1201	1246	25	17	17	CD
cord-022561-rv5j1201	1246	26	)	)	-RRB-
cord-022561-rv5j1201	1246	27	,	,	,
cord-022561-rv5j1201	1246	28	but	but	CC
cord-022561-rv5j1201	1246	29	mast	mast	JJ
cord-022561-rv5j1201	1246	30	cell	cell	NN
cord-022561-rv5j1201	1246	31	leukemia	leukemia	NN
cord-022561-rv5j1201	1246	32	is	be	VBZ
cord-022561-rv5j1201	1246	33	rare	rare	JJ
cord-022561-rv5j1201	1246	34	.	.	.
cord-022561-rv5j1201	1247	1	In	in	IN
cord-022561-rv5j1201	1247	2	cats	cat	NNS
cord-022561-rv5j1201	1247	3	,	,	,
cord-022561-rv5j1201	1247	4	MCTs	mct	NNS
cord-022561-rv5j1201	1247	5	are	be	VBP
cord-022561-rv5j1201	1247	6	the	the	DT
cord-022561-rv5j1201	1247	7	most	most	RBS
cord-022561-rv5j1201	1247	8	common	common	JJ
cord-022561-rv5j1201	1247	9	neoplasm	neoplasm	NN
cord-022561-rv5j1201	1247	10	in	in	IN
cord-022561-rv5j1201	1247	11	the	the	DT
cord-022561-rv5j1201	1247	12	spleen	spleen	NN
cord-022561-rv5j1201	1248	1	(	(	-LRB-
cord-022561-rv5j1201	1248	2	E-	E-	NNP
cord-022561-rv5j1201	1248	3	Fig	Fig	NNP
cord-022561-rv5j1201	1248	4	.	.	.
cord-022561-rv5j1201	1248	5	13	13	CD
cord-022561-rv5j1201	1248	6	-	-	SYM
cord-022561-rv5j1201	1248	7	6	6	CD
cord-022561-rv5j1201	1248	8	)	)	-RRB-
cord-022561-rv5j1201	1248	9	.	.	.
cord-022561-rv5j1201	1249	1	Mast	mast	NN
cord-022561-rv5j1201	1249	2	cells	cell	NNS
cord-022561-rv5j1201	1249	3	normally	normally	RB
cord-022561-rv5j1201	1249	4	are	be	VBP
cord-022561-rv5j1201	1249	5	not	not	RB
cord-022561-rv5j1201	1249	6	present	present	JJ
cord-022561-rv5j1201	1249	7	in	in	IN
cord-022561-rv5j1201	1249	8	the	the	DT
cord-022561-rv5j1201	1249	9	blood	blood	NN
cord-022561-rv5j1201	1249	10	vascular	vascular	JJ
cord-022561-rv5j1201	1249	11	system	system	NN
cord-022561-rv5j1201	1249	12	,	,	,
cord-022561-rv5j1201	1249	13	but	but	CC
cord-022561-rv5j1201	1249	14	the	the	DT
cord-022561-rv5j1201	1249	15	finding	finding	NN
cord-022561-rv5j1201	1249	16	of	of	IN
cord-022561-rv5j1201	1249	17	mast	mast	NN
cord-022561-rv5j1201	1249	18	cells	cell	NNS
cord-022561-rv5j1201	1249	19	in	in	IN
cord-022561-rv5j1201	1249	20	the	the	DT
cord-022561-rv5j1201	1249	21	blood	blood	NN
cord-022561-rv5j1201	1249	22	(	(	-LRB-
cord-022561-rv5j1201	1249	23	mastocytemia	mastocytemia	NNP
cord-022561-rv5j1201	1249	24	)	)	-RRB-
cord-022561-rv5j1201	1249	25	is	be	VBZ
cord-022561-rv5j1201	1249	26	highly	highly	RB
cord-022561-rv5j1201	1249	27	suggestive	suggestive	JJ
cord-022561-rv5j1201	1249	28	of	of	IN
cord-022561-rv5j1201	1249	29	disseminated	disseminate	VBN
cord-022561-rv5j1201	1249	30	mast	mast	JJ
cord-022561-rv5j1201	1249	31	cell	cell	NN
cord-022561-rv5j1201	1249	32	neoplasia	neoplasia	NN
cord-022561-rv5j1201	1249	33	(	(	-LRB-
cord-022561-rv5j1201	1249	34	systemic	systemic	JJ
cord-022561-rv5j1201	1249	35	mastocytosis	mastocytosis	NN
cord-022561-rv5j1201	1249	36	)	)	-RRB-
cord-022561-rv5j1201	1249	37	in	in	IN
cord-022561-rv5j1201	1249	38	cats	cat	NNS
cord-022561-rv5j1201	1249	39	.	.	.
cord-022561-rv5j1201	1250	1	However	however	RB
cord-022561-rv5j1201	1250	2	,	,	,
cord-022561-rv5j1201	1250	3	mastocytemia	mastocytemia	NNP
cord-022561-rv5j1201	1250	4	does	do	VBZ
cord-022561-rv5j1201	1250	5	not	not	RB
cord-022561-rv5j1201	1250	6	necessarily	necessarily	RB
cord-022561-rv5j1201	1250	7	indicate	indicate	VB
cord-022561-rv5j1201	1250	8	myeloid	myeloid	JJ
cord-022561-rv5j1201	1250	9	neoplasia	neoplasia	NN
cord-022561-rv5j1201	1250	10	in	in	IN
cord-022561-rv5j1201	1250	11	dogs	dog	NNS
cord-022561-rv5j1201	1250	12	.	.	.
cord-022561-rv5j1201	1251	1	In	in	IN
cord-022561-rv5j1201	1251	2	fact	fact	NN
cord-022561-rv5j1201	1251	3	,	,	,
cord-022561-rv5j1201	1251	4	one	one	CD
cord-022561-rv5j1201	1251	5	study	study	NN
cord-022561-rv5j1201	1251	6	found	find	VBD
cord-022561-rv5j1201	1251	7	that	that	IN
cord-022561-rv5j1201	1251	8	the	the	DT
cord-022561-rv5j1201	1251	9	severity	severity	NN
cord-022561-rv5j1201	1251	10	of	of	IN
cord-022561-rv5j1201	1251	11	mastocytemia	mastocytemia	NNP
cord-022561-rv5j1201	1251	12	in	in	IN
cord-022561-rv5j1201	1251	13	dogs	dog	NNS
cord-022561-rv5j1201	1251	14	was	be	VBD
cord-022561-rv5j1201	1251	15	frequently	frequently	RB
cord-022561-rv5j1201	1251	16	higher	high	JJR
cord-022561-rv5j1201	1251	17	in	in	IN
cord-022561-rv5j1201	1251	18	animals	animal	NNS
cord-022561-rv5j1201	1251	19	without	without	IN
cord-022561-rv5j1201	1251	20	MCTs	mct	NNS
cord-022561-rv5j1201	1251	21	than	than	IN
cord-022561-rv5j1201	1251	22	those	those	DT
cord-022561-rv5j1201	1251	23	with	with	IN
cord-022561-rv5j1201	1251	24	MCTs	mct	NNS
cord-022561-rv5j1201	1251	25	and	and	CC
cord-022561-rv5j1201	1251	26	that	that	IN
cord-022561-rv5j1201	1251	27	random	random	JJ
cord-022561-rv5j1201	1251	28	detection	detection	NN
cord-022561-rv5j1201	1251	29	of	of	IN
cord-022561-rv5j1201	1251	30	mast	mast	NN
cord-022561-rv5j1201	1251	31	cells	cell	NNS
cord-022561-rv5j1201	1251	32	in	in	IN
cord-022561-rv5j1201	1251	33	blood	blood	NN
cord-022561-rv5j1201	1251	34	smears	smear	NNS
cord-022561-rv5j1201	1251	35	usually	usually	RB
cord-022561-rv5j1201	1251	36	is	be	VBZ
cord-022561-rv5j1201	1251	37	not	not	RB
cord-022561-rv5j1201	1251	38	the	the	DT
cord-022561-rv5j1201	1251	39	result	result	NN
cord-022561-rv5j1201	1251	40	of	of	IN
cord-022561-rv5j1201	1251	41	underlying	underlie	VBG
cord-022561-rv5j1201	1251	42	MCT	MCT	NNP
cord-022561-rv5j1201	1251	43	.	.	.
cord-022561-rv5j1201	1252	1	Granulocytic	granulocytic	JJ
cord-022561-rv5j1201	1252	2	Sarcoma	Sarcoma	NNP
cord-022561-rv5j1201	1252	3	.	.	.
cord-022561-rv5j1201	1253	1	Granulocytic	granulocytic	JJ
cord-022561-rv5j1201	1253	2	sarcoma	sarcoma	NN
cord-022561-rv5j1201	1253	3	is	be	VBZ
cord-022561-rv5j1201	1253	4	a	a	DT
cord-022561-rv5j1201	1253	5	poorly	poorly	RB
cord-022561-rv5j1201	1253	6	characterized	characterize	VBN
cord-022561-rv5j1201	1253	7	extramedullary	extramedullary	JJ
cord-022561-rv5j1201	1253	8	proliferation	proliferation	NN
cord-022561-rv5j1201	1253	9	of	of	IN
cord-022561-rv5j1201	1253	10	myeloid	myeloid	JJ
cord-022561-rv5j1201	1253	11	precursors	precursor	NNS
cord-022561-rv5j1201	1253	12	,	,	,
cord-022561-rv5j1201	1253	13	most	most	RBS
cord-022561-rv5j1201	1253	14	typically	typically	RB
cord-022561-rv5j1201	1253	15	have	have	VBP
cord-022561-rv5j1201	1253	16	indolent	indolent	JJ
cord-022561-rv5j1201	1253	17	,	,	,
cord-022561-rv5j1201	1253	18	slowly	slowly	RB
cord-022561-rv5j1201	1253	19	progressive	progressive	JJ
cord-022561-rv5j1201	1253	20	disease	disease	NN
cord-022561-rv5j1201	1253	21	.	.	.
cord-022561-rv5j1201	1254	1	This	this	DT
cord-022561-rv5j1201	1254	2	classification	classification	NN
cord-022561-rv5j1201	1254	3	scheme	scheme	NN
cord-022561-rv5j1201	1254	4	is	be	VBZ
cord-022561-rv5j1201	1254	5	summarized	summarize	VBN
cord-022561-rv5j1201	1254	6	in	in	IN
cord-022561-rv5j1201	1254	7	Table	Table	NNP
cord-022561-rv5j1201	1254	8	13	13	CD
cord-022561-rv5j1201	1254	9	-4	-4	NNS
cord-022561-rv5j1201	1254	10	.	.	.
cord-022561-rv5j1201	1255	1	Subcategories	subcategorie	NNS
cord-022561-rv5j1201	1255	2	exist	exist	VBP
cord-022561-rv5j1201	1255	3	within	within	IN
cord-022561-rv5j1201	1255	4	each	each	DT
cord-022561-rv5j1201	1255	5	of	of	IN
cord-022561-rv5j1201	1255	6	these	these	DT
cord-022561-rv5j1201	1255	7	groups	group	NNS
cord-022561-rv5j1201	1255	8	,	,	,
cord-022561-rv5j1201	1255	9	as	as	IN
cord-022561-rv5j1201	1255	10	discussed	discuss	VBN
cord-022561-rv5j1201	1255	11	further	further	RB
cord-022561-rv5j1201	1255	12	later	later	RB
cord-022561-rv5j1201	1255	13	.	.	.
cord-022561-rv5j1201	1256	1	Information	information	NN
cord-022561-rv5j1201	1256	2	on	on	IN
cord-022561-rv5j1201	1256	3	this	this	DT
cord-022561-rv5j1201	1256	4	topic	topic	NN
cord-022561-rv5j1201	1256	5	is	be	VBZ
cord-022561-rv5j1201	1256	6	available	available	JJ
cord-022561-rv5j1201	1256	7	at	at	IN
cord-022561-rv5j1201	1256	8	www.expertconsult.com	www.expertconsult.com	ADD
cord-022561-rv5j1201	1256	9	.	.	.
cord-022561-rv5j1201	1257	1	This	this	DT
cord-022561-rv5j1201	1257	2	section	section	NN
cord-022561-rv5j1201	1257	3	discusses	discuss	VBZ
cord-022561-rv5j1201	1257	4	examples	example	NNS
cord-022561-rv5j1201	1257	5	of	of	IN
cord-022561-rv5j1201	1257	6	myeloid	myeloid	JJ
cord-022561-rv5j1201	1257	7	neoplasms	neoplasm	NNS
cord-022561-rv5j1201	1257	8	,	,	,
cord-022561-rv5j1201	1257	9	including	include	VBG
cord-022561-rv5j1201	1257	10	myelodysplastic	myelodysplastic	JJ
cord-022561-rv5j1201	1257	11	syndrome	syndrome	NN
cord-022561-rv5j1201	1257	12	,	,	,
cord-022561-rv5j1201	1257	13	myeloid	myeloid	NN
cord-022561-rv5j1201	1257	14	leukemias	leukemias	RB
cord-022561-rv5j1201	1257	15	,	,	,
cord-022561-rv5j1201	1257	16	and	and	CC
cord-022561-rv5j1201	1257	17	mast	mast	NN
cord-022561-rv5j1201	1257	18	cell	cell	NN
cord-022561-rv5j1201	1257	19	neoplasms	neoplasm	NNS
cord-022561-rv5j1201	1257	20	(	(	-LRB-
cord-022561-rv5j1201	1257	21	technically	technically	RB
cord-022561-rv5j1201	1257	22	a	a	DT
cord-022561-rv5j1201	1257	23	form	form	NN
cord-022561-rv5j1201	1257	24	of	of	IN
cord-022561-rv5j1201	1257	25	myeloid	myeloid	JJ
cord-022561-rv5j1201	1257	26	neoplasia	neoplasia	NN
cord-022561-rv5j1201	1257	27	)	)	-RRB-
cord-022561-rv5j1201	1257	28	,	,	,
cord-022561-rv5j1201	1257	29	and	and	CC
cord-022561-rv5j1201	1257	30	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	1257	31	neoplasms	neoplasm	NNS
cord-022561-rv5j1201	1257	32	,	,	,
cord-022561-rv5j1201	1257	33	including	include	VBG
cord-022561-rv5j1201	1257	34	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	1257	35	leukemias	leukemia	NNS
cord-022561-rv5j1201	1257	36	and	and	CC
cord-022561-rv5j1201	1257	37	multiple	multiple	JJ
cord-022561-rv5j1201	1257	38	myeloma	myeloma	NN
cord-022561-rv5j1201	1257	39	.	.	.
cord-022561-rv5j1201	1258	1	Other	other	JJ
cord-022561-rv5j1201	1258	2	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	1258	3	neoplasms	neoplasm	NNS
cord-022561-rv5j1201	1258	4	,	,	,
cord-022561-rv5j1201	1258	5	such	such	JJ
cord-022561-rv5j1201	1258	6	as	as	IN
cord-022561-rv5j1201	1258	7	the	the	DT
cord-022561-rv5j1201	1258	8	numerous	numerous	JJ
cord-022561-rv5j1201	1258	9	subtypes	subtype	NNS
cord-022561-rv5j1201	1258	10	of	of	IN
cord-022561-rv5j1201	1258	11	lymphoma	lymphoma	NN
cord-022561-rv5j1201	1258	12	and	and	CC
cord-022561-rv5j1201	1258	13	extramedullary	extramedullary	JJ
cord-022561-rv5j1201	1258	14	plasmacytomas	plasmacytomas	NNP
cord-022561-rv5j1201	1258	15	(	(	-LRB-
cord-022561-rv5j1201	1258	16	EMPs	EMPs	NNP
cord-022561-rv5j1201	1258	17	)	)	-RRB-
cord-022561-rv5j1201	1258	18	,	,	,
cord-022561-rv5j1201	1258	19	as	as	RB
cord-022561-rv5j1201	1258	20	well	well	RB
cord-022561-rv5j1201	1258	21	as	as	IN
cord-022561-rv5j1201	1258	22	histiocytic	histiocytic	JJ
cord-022561-rv5j1201	1258	23	disorders	disorder	NNS
cord-022561-rv5j1201	1258	24	are	be	VBP
cord-022561-rv5j1201	1258	25	described	describe	VBN
cord-022561-rv5j1201	1258	26	in	in	IN
cord-022561-rv5j1201	1258	27	the	the	DT
cord-022561-rv5j1201	1258	28	section	section	NN
cord-022561-rv5j1201	1258	29	on	on	IN
cord-022561-rv5j1201	1258	30	Lymphoid	Lymphoid	NNP
cord-022561-rv5j1201	1258	31	/	/	SYM
cord-022561-rv5j1201	1258	32	Lymphatic	Lymphatic	NNP
cord-022561-rv5j1201	1258	33	System	System	NNP
cord-022561-rv5j1201	1258	34	,	,	,
cord-022561-rv5j1201	1258	35	Disorders	Disorders	NNPS
cord-022561-rv5j1201	1258	36	of	of	IN
cord-022561-rv5j1201	1258	37	Domestic	domestic	JJ
cord-022561-rv5j1201	1258	38	Animals	Animals	NNPS
cord-022561-rv5j1201	1258	39	,	,	,
cord-022561-rv5j1201	1258	40	Neoplasia	Neoplasia	NNP
cord-022561-rv5j1201	1258	41	.	.	.
cord-022561-rv5j1201	1259	1	Additional	additional	JJ
cord-022561-rv5j1201	1259	2	discussion	discussion	NN
cord-022561-rv5j1201	1259	3	of	of	IN
cord-022561-rv5j1201	1259	4	hematopoietic	hematopoietic	JJ
cord-022561-rv5j1201	1259	5	neoplasia	neoplasia	NN
cord-022561-rv5j1201	1259	6	occurs	occur	VBZ
cord-022561-rv5j1201	1259	7	in	in	IN
cord-022561-rv5j1201	1259	8	the	the	DT
cord-022561-rv5j1201	1259	9	species	species	NN
cord-022561-rv5j1201	1259	10	-	-	HYPH
cord-022561-rv5j1201	1259	11	specific	specific	JJ
cord-022561-rv5j1201	1259	12	sections	section	NNS
cord-022561-rv5j1201	1259	13	at	at	IN
cord-022561-rv5j1201	1259	14	the	the	DT
cord-022561-rv5j1201	1259	15	end	end	NN
cord-022561-rv5j1201	1259	16	of	of	IN
cord-022561-rv5j1201	1259	17	this	this	DT
cord-022561-rv5j1201	1259	18	chapter	chapter	NN
cord-022561-rv5j1201	1259	19	.	.	.
cord-022561-rv5j1201	1260	1	Myelodysplastic	Myelodysplastic	NNP
cord-022561-rv5j1201	1260	2	Syndrome	Syndrome	NNP
cord-022561-rv5j1201	1260	3	.	.	.
cord-022561-rv5j1201	1261	1	Myelodysplastic	myelodysplastic	JJ
cord-022561-rv5j1201	1261	2	syndrome	syndrome	NN
cord-022561-rv5j1201	1261	3	(	(	-LRB-
cord-022561-rv5j1201	1261	4	MDS	MDS	NNP
cord-022561-rv5j1201	1261	5	)	)	-RRB-
cord-022561-rv5j1201	1261	6	most	most	RBS
cord-022561-rv5j1201	1261	7	commonly	commonly	RB
cord-022561-rv5j1201	1261	8	occurs	occur	VBZ
cord-022561-rv5j1201	1261	9	in	in	IN
cord-022561-rv5j1201	1261	10	dogs	dog	NNS
cord-022561-rv5j1201	1261	11	and	and	CC
cord-022561-rv5j1201	1261	12	cats	cat	NNS
cord-022561-rv5j1201	1261	13	and	and	CC
cord-022561-rv5j1201	1261	14	may	may	MD
cord-022561-rv5j1201	1261	15	be	be	VB
cord-022561-rv5j1201	1261	16	caused	cause	VBN
cord-022561-rv5j1201	1261	17	by	by	IN
cord-022561-rv5j1201	1261	18	FeLV	FeLV	NNP
cord-022561-rv5j1201	1261	19	infection	infection	NN
cord-022561-rv5j1201	1261	20	in	in	IN
cord-022561-rv5j1201	1261	21	cats	cat	NNS
cord-022561-rv5j1201	1261	22	.	.	.
cord-022561-rv5j1201	1262	1	The	the	DT
cord-022561-rv5j1201	1262	2	disease	disease	NN
cord-022561-rv5j1201	1262	3	refers	refer	VBZ
cord-022561-rv5j1201	1262	4	to	to	IN
cord-022561-rv5j1201	1262	5	a	a	DT
cord-022561-rv5j1201	1262	6	group	group	NN
cord-022561-rv5j1201	1262	7	of	of	IN
cord-022561-rv5j1201	1262	8	clonal	clonal	JJ
cord-022561-rv5j1201	1262	9	myeloid	myeloid	JJ
cord-022561-rv5j1201	1262	10	proliferative	proliferative	JJ
cord-022561-rv5j1201	1262	11	disorders	disorder	NNS
cord-022561-rv5j1201	1262	12	with	with	IN
cord-022561-rv5j1201	1262	13	ineffective	ineffective	JJ
cord-022561-rv5j1201	1262	14	hematopoiesis	hematopoiesis	NN
cord-022561-rv5j1201	1262	15	in	in	IN
cord-022561-rv5j1201	1262	16	the	the	DT
cord-022561-rv5j1201	1262	17	bone	bone	NN
cord-022561-rv5j1201	1262	18	marrow	marrow	NN
cord-022561-rv5j1201	1262	19	,	,	,
cord-022561-rv5j1201	1262	20	resulting	result	VBG
cord-022561-rv5j1201	1262	21	in	in	IN
cord-022561-rv5j1201	1262	22	cytopenias	cytopenia	NNS
cord-022561-rv5j1201	1262	23	of	of	IN
cord-022561-rv5j1201	1262	24	more	more	JJR
cord-022561-rv5j1201	1262	25	than	than	IN
cord-022561-rv5j1201	1262	26	one	one	CD
cord-022561-rv5j1201	1262	27	cell	cell	NN
cord-022561-rv5j1201	1262	28	line	line	NN
cord-022561-rv5j1201	1262	29	.	.	.
cord-022561-rv5j1201	1263	1	Hematopoietic	hematopoietic	JJ
cord-022561-rv5j1201	1263	2	proliferation	proliferation	NN
cord-022561-rv5j1201	1263	3	in	in	IN
cord-022561-rv5j1201	1263	4	bone	bone	NN
cord-022561-rv5j1201	1263	5	marrow	marrow	NN
cord-022561-rv5j1201	1263	6	with	with	IN
cord-022561-rv5j1201	1263	7	concurrent	concurrent	JJ
cord-022561-rv5j1201	1263	8	peripheral	peripheral	JJ
cord-022561-rv5j1201	1263	9	blood	blood	NN
cord-022561-rv5j1201	1263	10	cytopenias	cytopenia	NNS
cord-022561-rv5j1201	1263	11	is	be	VBZ
cord-022561-rv5j1201	1263	12	likely	likely	RB
cord-022561-rv5j1201	1263	13	a	a	DT
cord-022561-rv5j1201	1263	14	result	result	NN
cord-022561-rv5j1201	1263	15	of	of	IN
cord-022561-rv5j1201	1263	16	increased	increase	VBN
cord-022561-rv5j1201	1263	17	apoptosis	apoptosis	NN
cord-022561-rv5j1201	1263	18	of	of	IN
cord-022561-rv5j1201	1263	19	neoplastic	neoplastic	JJ
cord-022561-rv5j1201	1263	20	cells	cell	NNS
cord-022561-rv5j1201	1263	21	within	within	IN
cord-022561-rv5j1201	1263	22	the	the	DT
cord-022561-rv5j1201	1263	23	bone	bone	NN
cord-022561-rv5j1201	1263	24	marrow	marrow	NN
cord-022561-rv5j1201	1263	25	,	,	,
cord-022561-rv5j1201	1263	26	before	before	IN
cord-022561-rv5j1201	1263	27	their	-PRON-	PRP$
cord-022561-rv5j1201	1263	28	release	release	NN
cord-022561-rv5j1201	1263	29	into	into	IN
cord-022561-rv5j1201	1263	30	circulation	circulation	NN
cord-022561-rv5j1201	1263	31	.	.	.
cord-022561-rv5j1201	1264	1	Clinical	clinical	JJ
cord-022561-rv5j1201	1264	2	illness	illness	NN
cord-022561-rv5j1201	1264	3	and	and	CC
cord-022561-rv5j1201	1264	4	death	death	NN
cord-022561-rv5j1201	1264	5	often	often	RB
cord-022561-rv5j1201	1264	6	result	result	VBP
cord-022561-rv5j1201	1264	7	from	from	IN
cord-022561-rv5j1201	1264	8	secondary	secondary	JJ
cord-022561-rv5j1201	1264	9	manifestations	manifestation	NNS
cord-022561-rv5j1201	1264	10	,	,	,
cord-022561-rv5j1201	1264	11	such	such	JJ
cord-022561-rv5j1201	1264	12	as	as	IN
cord-022561-rv5j1201	1264	13	secondary	secondary	JJ
cord-022561-rv5j1201	1264	14	infections	infection	NNS
cord-022561-rv5j1201	1264	15	or	or	CC
cord-022561-rv5j1201	1264	16	cachexia	cachexia	NN
cord-022561-rv5j1201	1264	17	,	,	,
cord-022561-rv5j1201	1264	18	attributable	attributable	JJ
cord-022561-rv5j1201	1264	19	to	to	IN
cord-022561-rv5j1201	1264	20	the	the	DT
cord-022561-rv5j1201	1264	21	effects	effect	NNS
cord-022561-rv5j1201	1264	22	of	of	IN
cord-022561-rv5j1201	1264	23	cytopenias	cytopenia	NNS
cord-022561-rv5j1201	1264	24	and/or	and/or	CC
cord-022561-rv5j1201	1264	25	transformation	transformation	NN
cord-022561-rv5j1201	1264	26	of	of	IN
cord-022561-rv5j1201	1264	27	the	the	DT
cord-022561-rv5j1201	1264	28	neoplasm	neoplasm	NN
cord-022561-rv5j1201	1264	29	into	into	IN
cord-022561-rv5j1201	1264	30	acute	acute	JJ
cord-022561-rv5j1201	1264	31	myeloid	myeloid	JJ
cord-022561-rv5j1201	1264	32	leukemia	leukemia	NN
cord-022561-rv5j1201	1264	33	.	.	.
cord-022561-rv5j1201	1265	1	Gross	gross	JJ
cord-022561-rv5j1201	1265	2	lesions	lesion	NNS
cord-022561-rv5j1201	1265	3	are	be	VBP
cord-022561-rv5j1201	1265	4	dependent	dependent	JJ
cord-022561-rv5j1201	1265	5	upon	upon	IN
cord-022561-rv5j1201	1265	6	the	the	DT
cord-022561-rv5j1201	1265	7	type	type	NN
cord-022561-rv5j1201	1265	8	and	and	CC
cord-022561-rv5j1201	1265	9	severity	severity	NN
cord-022561-rv5j1201	1265	10	of	of	IN
cord-022561-rv5j1201	1265	11	the	the	DT
cord-022561-rv5j1201	1265	12	cytopenias	cytopenia	NNS
cord-022561-rv5j1201	1265	13	.	.	.
cord-022561-rv5j1201	1266	1	However	however	RB
cord-022561-rv5j1201	1266	2	,	,	,
cord-022561-rv5j1201	1266	3	essential	essential	JJ
cord-022561-rv5j1201	1266	4	microscopic	microscopic	JJ
cord-022561-rv5j1201	1266	5	findings	finding	NNS
cord-022561-rv5j1201	1266	6	within	within	IN
cord-022561-rv5j1201	1266	7	the	the	DT
cord-022561-rv5j1201	1266	8	bone	bone	NN
cord-022561-rv5j1201	1266	9	marrow	marrow	NN
cord-022561-rv5j1201	1266	10	are	be	VBP
cord-022561-rv5j1201	1266	11	normal	normal	JJ
cord-022561-rv5j1201	1266	12	or	or	CC
cord-022561-rv5j1201	1266	13	increased	increase	VBN
cord-022561-rv5j1201	1266	14	cellularity	cellularity	NN
cord-022561-rv5j1201	1266	15	,	,	,
cord-022561-rv5j1201	1266	16	3	3	CD
cord-022561-rv5j1201	1266	17	"	"	``
cord-022561-rv5j1201	1266	18	Blast	blast	NN
cord-022561-rv5j1201	1266	19	equivalents	equivalent	NNS
cord-022561-rv5j1201	1266	20	"	"	''
cord-022561-rv5j1201	1266	21	include	include	VBP
cord-022561-rv5j1201	1266	22	other	other	JJ
cord-022561-rv5j1201	1266	23	stages	stage	NNS
cord-022561-rv5j1201	1266	24	of	of	IN
cord-022561-rv5j1201	1266	25	immature	immature	JJ
cord-022561-rv5j1201	1266	26	myeloid	myeloid	NN
cord-022561-rv5j1201	1266	27	cells	cell	NNS
cord-022561-rv5j1201	1266	28	,	,	,
cord-022561-rv5j1201	1266	29	such	such	JJ
cord-022561-rv5j1201	1266	30	as	as	IN
cord-022561-rv5j1201	1266	31	abnormal	abnormal	JJ
cord-022561-rv5j1201	1266	32	promyelocytes	promyelocyte	NNS
cord-022561-rv5j1201	1266	33	,	,	,
cord-022561-rv5j1201	1266	34	monoblasts	monoblast	NNS
cord-022561-rv5j1201	1266	35	,	,	,
cord-022561-rv5j1201	1266	36	promonocytes	promonocyte	NNS
cord-022561-rv5j1201	1266	37	,	,	,
cord-022561-rv5j1201	1266	38	erythroblasts	erythroblast	NNS
cord-022561-rv5j1201	1266	39	,	,	,
cord-022561-rv5j1201	1266	40	and	and	CC
cord-022561-rv5j1201	1266	41	megakaryoblasts	megakaryoblast	NNS
cord-022561-rv5j1201	1266	42	.	.	.
cord-022561-rv5j1201	1267	1	Before	before	IN
cord-022561-rv5j1201	1267	2	the	the	DT
cord-022561-rv5j1201	1267	3	discussion	discussion	NN
cord-022561-rv5j1201	1267	4	of	of	IN
cord-022561-rv5j1201	1267	5	specific	specific	JJ
cord-022561-rv5j1201	1267	6	diseases	disease	NNS
cord-022561-rv5j1201	1267	7	,	,	,
cord-022561-rv5j1201	1267	8	it	-PRON-	PRP
cord-022561-rv5j1201	1267	9	is	be	VBZ
cord-022561-rv5j1201	1267	10	worthwhile	worthwhile	JJ
cord-022561-rv5j1201	1267	11	to	to	TO
cord-022561-rv5j1201	1267	12	describe	describe	VB
cord-022561-rv5j1201	1267	13	the	the	DT
cord-022561-rv5j1201	1267	14	diagnostic	diagnostic	JJ
cord-022561-rv5j1201	1267	15	techniques	technique	NNS
cord-022561-rv5j1201	1267	16	required	require	VBN
cord-022561-rv5j1201	1267	17	to	to	TO
cord-022561-rv5j1201	1267	18	classify	classify	VB
cord-022561-rv5j1201	1267	19	hematopoietic	hematopoietic	JJ
cord-022561-rv5j1201	1267	20	neoplasms	neoplasm	NNS
cord-022561-rv5j1201	1267	21	that	that	WDT
cord-022561-rv5j1201	1267	22	are	be	VBP
cord-022561-rv5j1201	1267	23	becoming	become	VBG
cord-022561-rv5j1201	1267	24	increasingly	increasingly	RB
cord-022561-rv5j1201	1267	25	available	available	JJ
cord-022561-rv5j1201	1267	26	for	for	IN
cord-022561-rv5j1201	1267	27	routine	routine	JJ
cord-022561-rv5j1201	1267	28	use	use	NN
cord-022561-rv5j1201	1267	29	in	in	IN
cord-022561-rv5j1201	1267	30	veterinary	veterinary	JJ
cord-022561-rv5j1201	1267	31	medicine	medicine	NN
cord-022561-rv5j1201	1267	32	.	.	.
cord-022561-rv5j1201	1268	1	Immunophenotyping	immunophenotyping	NN
cord-022561-rv5j1201	1268	2	refers	refer	VBZ
cord-022561-rv5j1201	1268	3	to	to	IN
cord-022561-rv5j1201	1268	4	the	the	DT
cord-022561-rv5j1201	1268	5	use	use	NN
cord-022561-rv5j1201	1268	6	of	of	IN
cord-022561-rv5j1201	1268	7	antibodies	antibody	NNS
cord-022561-rv5j1201	1268	8	recognizing	recognize	VBG
cord-022561-rv5j1201	1268	9	specific	specific	JJ
cord-022561-rv5j1201	1268	10	molecules	molecule	NNS
cord-022561-rv5j1201	1268	11	expressed	express	VBN
cord-022561-rv5j1201	1268	12	on	on	IN
cord-022561-rv5j1201	1268	13	different	different	JJ
cord-022561-rv5j1201	1268	14	cell	cell	NN
cord-022561-rv5j1201	1268	15	types	type	NNS
cord-022561-rv5j1201	1268	16	to	to	TO
cord-022561-rv5j1201	1268	17	determine	determine	VB
cord-022561-rv5j1201	1268	18	the	the	DT
cord-022561-rv5j1201	1268	19	identity	identity	NN
cord-022561-rv5j1201	1268	20	of	of	IN
cord-022561-rv5j1201	1268	21	a	a	DT
cord-022561-rv5j1201	1268	22	cell	cell	NN
cord-022561-rv5j1201	1268	23	population	population	NN
cord-022561-rv5j1201	1268	24	of	of	IN
cord-022561-rv5j1201	1268	25	interest	interest	NN
cord-022561-rv5j1201	1268	26	.	.	.
cord-022561-rv5j1201	1269	1	Immunophenotyping	immunophenotype	VBG
cord-022561-rv5j1201	1269	2	on	on	IN
cord-022561-rv5j1201	1269	3	the	the	DT
cord-022561-rv5j1201	1269	4	basis	basis	NN
cord-022561-rv5j1201	1269	5	of	of	IN
cord-022561-rv5j1201	1269	6	these	these	DT
cord-022561-rv5j1201	1269	7	lineage	lineage	NN
cord-022561-rv5j1201	1269	8	-	-	HYPH
cord-022561-rv5j1201	1269	9	specific	specific	JJ
cord-022561-rv5j1201	1269	10	or	or	CC
cord-022561-rv5j1201	1269	11	lineage	lineage	NN
cord-022561-rv5j1201	1269	12	-	-	HYPH
cord-022561-rv5j1201	1269	13	associated	associate	VBN
cord-022561-rv5j1201	1269	14	markers	marker	NNS
cord-022561-rv5j1201	1269	15	can	can	MD
cord-022561-rv5j1201	1269	16	be	be	VB
cord-022561-rv5j1201	1269	17	performed	perform	VBN
cord-022561-rv5j1201	1269	18	on	on	IN
cord-022561-rv5j1201	1269	19	histologic	histologic	JJ
cord-022561-rv5j1201	1269	20	sections	section	NNS
cord-022561-rv5j1201	1269	21	(	(	-LRB-
cord-022561-rv5j1201	1269	22	immunohistochemistry	immunohistochemistry	JJ
cord-022561-rv5j1201	1269	23	[	[	-LRB-
cord-022561-rv5j1201	1269	24	see	see	VB
cord-022561-rv5j1201	1269	25	Fig	Fig	NNP
cord-022561-rv5j1201	1269	26	.	.	.
cord-022561-rv5j1201	1269	27	13	13	CD
cord-022561-rv5j1201	1269	28	-86	-86	NNP
cord-022561-rv5j1201	1269	29	]	]	-RRB-
cord-022561-rv5j1201	1269	30	)	)	-RRB-
cord-022561-rv5j1201	1269	31	,	,	,
cord-022561-rv5j1201	1269	32	air	air	NN
cord-022561-rv5j1201	1269	33	-	-	HYPH
cord-022561-rv5j1201	1269	34	dried	dry	VBN
cord-022561-rv5j1201	1269	35	cytologic	cytologic	JJ
cord-022561-rv5j1201	1269	36	examination	examination	NN
cord-022561-rv5j1201	1269	37	smears	smear	NNS
cord-022561-rv5j1201	1269	38	(	(	-LRB-
cord-022561-rv5j1201	1269	39	immunocytochemistry	immunocytochemistry	NNP
cord-022561-rv5j1201	1269	40	)	)	-RRB-
cord-022561-rv5j1201	1269	41	,	,	,
cord-022561-rv5j1201	1269	42	or	or	CC
cord-022561-rv5j1201	1269	43	by	by	IN
cord-022561-rv5j1201	1269	44	laser	laser	NN
cord-022561-rv5j1201	1269	45	analysis	analysis	NN
cord-022561-rv5j1201	1269	46	of	of	IN
cord-022561-rv5j1201	1269	47	cells	cell	NNS
cord-022561-rv5j1201	1269	48	in	in	IN
cord-022561-rv5j1201	1269	49	suspension	suspension	NN
cord-022561-rv5j1201	1269	50	in	in	IN
cord-022561-rv5j1201	1269	51	blood	blood	NN
cord-022561-rv5j1201	1269	52	or	or	CC
cord-022561-rv5j1201	1269	53	buffer	buffer	NN
cord-022561-rv5j1201	1269	54	solutions	solution	NNS
cord-022561-rv5j1201	1269	55	(	(	-LRB-
cord-022561-rv5j1201	1269	56	flow	flow	NN
cord-022561-rv5j1201	1269	57	cytometry	cytometry	NN
cord-022561-rv5j1201	1269	58	)	)	-RRB-
cord-022561-rv5j1201	1269	59	.	.	.
cord-022561-rv5j1201	1270	1	In	in	IN
cord-022561-rv5j1201	1270	2	cases	case	NNS
cord-022561-rv5j1201	1270	3	of	of	IN
cord-022561-rv5j1201	1270	4	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	1270	5	neoplasia	neoplasia	NN
cord-022561-rv5j1201	1270	6	,	,	,
cord-022561-rv5j1201	1270	7	immunophenotyping	immunophenotype	VBG
cord-022561-rv5j1201	1270	8	most	most	RBS
cord-022561-rv5j1201	1270	9	routinely	routinely	RB
cord-022561-rv5j1201	1270	10	refers	refer	VBZ
cord-022561-rv5j1201	1270	11	to	to	IN
cord-022561-rv5j1201	1270	12	determination	determination	NN
cord-022561-rv5j1201	1270	13	of	of	IN
cord-022561-rv5j1201	1270	14	B	B	NNP
cord-022561-rv5j1201	1270	15	or	or	CC
cord-022561-rv5j1201	1270	16	T	T	NNP
cord-022561-rv5j1201	1270	17	lymphocyte	lymphocyte	NN
cord-022561-rv5j1201	1270	18	origin	origin	NN
cord-022561-rv5j1201	1270	19	.	.	.
cord-022561-rv5j1201	1271	1	Clonality	clonality	NN
cord-022561-rv5j1201	1271	2	assays	assay	NNS
cord-022561-rv5j1201	1271	3	,	,	,
cord-022561-rv5j1201	1271	4	PCR	PCR	NNP
cord-022561-rv5j1201	1271	5	for	for	IN
cord-022561-rv5j1201	1271	6	antigen	antigen	NN
cord-022561-rv5j1201	1271	7	receptor	receptor	NN
cord-022561-rv5j1201	1271	8	rearrangement	rearrangement	NN
cord-022561-rv5j1201	1271	9	(	(	-LRB-
cord-022561-rv5j1201	1271	10	PARR	PARR	NNP
cord-022561-rv5j1201	1271	11	)	)	-RRB-
cord-022561-rv5j1201	1271	12	,	,	,
cord-022561-rv5j1201	1271	13	can	can	MD
cord-022561-rv5j1201	1271	14	help	help	VB
cord-022561-rv5j1201	1271	15	identify	identify	VB
cord-022561-rv5j1201	1271	16	neoplastic	neoplastic	JJ
cord-022561-rv5j1201	1271	17	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	1271	18	proliferations	proliferation	NNS
cord-022561-rv5j1201	1271	19	on	on	IN
cord-022561-rv5j1201	1271	20	the	the	DT
cord-022561-rv5j1201	1271	21	basis	basis	NN
cord-022561-rv5j1201	1271	22	of	of	IN
cord-022561-rv5j1201	1271	23	clonal	clonal	JJ
cord-022561-rv5j1201	1271	24	rearrangements	rearrangement	NNS
cord-022561-rv5j1201	1271	25	of	of	IN
cord-022561-rv5j1201	1271	26	genes	gene	NNS
cord-022561-rv5j1201	1271	27	encoding	encode	VBG
cord-022561-rv5j1201	1271	28	lymphocyte	lymphocyte	NN
cord-022561-rv5j1201	1271	29	antigen	antigen	NN
cord-022561-rv5j1201	1271	30	receptors	receptor	NNS
cord-022561-rv5j1201	1271	31	.	.	.
cord-022561-rv5j1201	1272	1	In	in	IN
cord-022561-rv5j1201	1272	2	terms	term	NNS
cord-022561-rv5j1201	1272	3	of	of	IN
cord-022561-rv5j1201	1272	4	practical	practical	JJ
cord-022561-rv5j1201	1272	5	application	application	NN
cord-022561-rv5j1201	1272	6	the	the	DT
cord-022561-rv5j1201	1272	7	PARR	PARR	NNP
cord-022561-rv5j1201	1272	8	assay	assay	NN
cord-022561-rv5j1201	1272	9	is	be	VBZ
cord-022561-rv5j1201	1272	10	most	most	RBS
cord-022561-rv5j1201	1272	11	useful	useful	JJ
cord-022561-rv5j1201	1272	12	in	in	IN
cord-022561-rv5j1201	1272	13	helping	help	VBG
cord-022561-rv5j1201	1272	14	to	to	TO
cord-022561-rv5j1201	1272	15	distinguish	distinguish	VB
cord-022561-rv5j1201	1272	16	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	1272	17	neoplasms	neoplasm	NNS
cord-022561-rv5j1201	1272	18	from	from	IN
cord-022561-rv5j1201	1272	19	those	those	DT
cord-022561-rv5j1201	1272	20	nonneoplastic	nonneoplastic	JJ
cord-022561-rv5j1201	1272	21	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	1272	22	proliferations	proliferation	NNS
cord-022561-rv5j1201	1272	23	mimicking	mimic	VBG
cord-022561-rv5j1201	1272	24	neoplasia	neoplasia	NN
cord-022561-rv5j1201	1272	25	.	.	.
cord-022561-rv5j1201	1273	1	Cytogenetic	cytogenetic	JJ
cord-022561-rv5j1201	1273	2	testing	testing	NN
cord-022561-rv5j1201	1273	3	has	have	VBZ
cord-022561-rv5j1201	1273	4	not	not	RB
cord-022561-rv5j1201	1273	5	been	be	VBN
cord-022561-rv5j1201	1273	6	routinely	routinely	RB
cord-022561-rv5j1201	1273	7	used	use	VBN
cord-022561-rv5j1201	1273	8	in	in	IN
cord-022561-rv5j1201	1273	9	veterinary	veterinary	JJ
cord-022561-rv5j1201	1273	10	medicine	medicine	NN
cord-022561-rv5j1201	1273	11	,	,	,
cord-022561-rv5j1201	1273	12	though	though	IN
cord-022561-rv5j1201	1273	13	several	several	JJ
cord-022561-rv5j1201	1273	14	genetic	genetic	JJ
cord-022561-rv5j1201	1273	15	mutations	mutation	NNS
cord-022561-rv5j1201	1273	16	have	have	VBP
cord-022561-rv5j1201	1273	17	been	be	VBN
cord-022561-rv5j1201	1273	18	identified	identify	VBN
cord-022561-rv5j1201	1273	19	in	in	IN
cord-022561-rv5j1201	1273	20	dogs	dog	NNS
cord-022561-rv5j1201	1273	21	.	.	.
cord-022561-rv5j1201	1274	1	For	for	IN
cord-022561-rv5j1201	1274	2	example	example	NN
cord-022561-rv5j1201	1274	3	,	,	,
cord-022561-rv5j1201	1274	4	breakpoint	breakpoint	NN
cord-022561-rv5j1201	1274	5	cluster	cluster	NN
cord-022561-rv5j1201	1274	6	region	region	NN
cord-022561-rv5j1201	1274	7	-	-	:
cord-022561-rv5j1201	1274	8	Abelson	Abelson	NNP
cord-022561-rv5j1201	1274	9	(	(	-LRB-
cord-022561-rv5j1201	1274	10	BCR	BCR	NNP
cord-022561-rv5j1201	1274	11	-	-	HYPH
cord-022561-rv5j1201	1274	12	ABL	ABL	NNP
cord-022561-rv5j1201	1274	13	)	)	-RRB-
cord-022561-rv5j1201	1274	14	translocations	translocation	NNS
cord-022561-rv5j1201	1274	15	have	have	VBP
cord-022561-rv5j1201	1274	16	been	be	VBN
cord-022561-rv5j1201	1274	17	identified	identify	VBN
cord-022561-rv5j1201	1274	18	in	in	IN
cord-022561-rv5j1201	1274	19	some	some	DT
cord-022561-rv5j1201	1274	20	canine	canine	JJ
cord-022561-rv5j1201	1274	21	leukemias	leukemia	NNS
cord-022561-rv5j1201	1274	22	,	,	,
cord-022561-rv5j1201	1274	23	including	include	VBG
cord-022561-rv5j1201	1274	24	acute	acute	JJ
cord-022561-rv5j1201	1274	25	myeloblastic	myeloblastic	JJ
cord-022561-rv5j1201	1274	26	leukemia	leukemia	NN
cord-022561-rv5j1201	1274	27	and	and	CC
cord-022561-rv5j1201	1274	28	chronic	chronic	JJ
cord-022561-rv5j1201	1274	29	monocytic	monocytic	JJ
cord-022561-rv5j1201	1274	30	leukemia	leukemia	NN
cord-022561-rv5j1201	1274	31	.	.	.
cord-022561-rv5j1201	1275	1	Dogs	dog	NNS
cord-022561-rv5j1201	1275	2	with	with	IN
cord-022561-rv5j1201	1275	3	Burkitt	Burkitt	NNP
cord-022561-rv5j1201	1275	4	-	-	HYPH
cord-022561-rv5j1201	1275	5	like	like	JJ
cord-022561-rv5j1201	1275	6	lymphoma	lymphoma	NN
cord-022561-rv5j1201	1275	7	have	have	VBP
cord-022561-rv5j1201	1275	8	a	a	DT
cord-022561-rv5j1201	1275	9	translocation	translocation	NN
cord-022561-rv5j1201	1275	10	leading	lead	VBG
cord-022561-rv5j1201	1275	11	to	to	IN
cord-022561-rv5j1201	1275	12	constitutive	constitutive	JJ
cord-022561-rv5j1201	1275	13	c	c	NN
cord-022561-rv5j1201	1275	14	-	-	HYPH
cord-022561-rv5j1201	1275	15	Myc	Myc	NNP
cord-022561-rv5j1201	1275	16	expression	expression	NN
cord-022561-rv5j1201	1275	17	.	.	.
cord-022561-rv5j1201	1276	1	A	a	DT
cord-022561-rv5j1201	1276	2	B	b	NN
cord-022561-rv5j1201	1276	3	thrombocytopenia	thrombocytopenia	NN
cord-022561-rv5j1201	1276	4	commonly	commonly	RB
cord-022561-rv5j1201	1276	5	occur	occur	VBP
cord-022561-rv5j1201	1276	6	.	.	.
cord-022561-rv5j1201	1277	1	Gross	gross	JJ
cord-022561-rv5j1201	1277	2	and	and	CC
cord-022561-rv5j1201	1277	3	microscopic	microscopic	JJ
cord-022561-rv5j1201	1277	4	lesions	lesion	NNS
cord-022561-rv5j1201	1277	5	also	also	RB
cord-022561-rv5j1201	1277	6	are	be	VBP
cord-022561-rv5j1201	1277	7	similar	similar	JJ
cord-022561-rv5j1201	1277	8	to	to	IN
cord-022561-rv5j1201	1277	9	those	those	DT
cord-022561-rv5j1201	1277	10	that	that	WDT
cord-022561-rv5j1201	1277	11	occur	occur	VBP
cord-022561-rv5j1201	1277	12	in	in	IN
cord-022561-rv5j1201	1277	13	cases	case	NNS
cord-022561-rv5j1201	1277	14	of	of	IN
cord-022561-rv5j1201	1277	15	acute	acute	JJ
cord-022561-rv5j1201	1277	16	myeloid	myeloid	NN
cord-022561-rv5j1201	1277	17	leukemia	leukemia	NN
cord-022561-rv5j1201	1277	18	,	,	,
cord-022561-rv5j1201	1277	19	except	except	IN
cord-022561-rv5j1201	1277	20	that	that	DT
cord-022561-rv5j1201	1277	21	neoplastic	neoplastic	JJ
cord-022561-rv5j1201	1277	22	cells	cell	NNS
cord-022561-rv5j1201	1277	23	may	may	MD
cord-022561-rv5j1201	1277	24	differentiate	differentiate	VB
cord-022561-rv5j1201	1277	25	into	into	IN
cord-022561-rv5j1201	1277	26	morphologically	morphologically	RB
cord-022561-rv5j1201	1277	27	identifiable	identifiable	JJ
cord-022561-rv5j1201	1277	28	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	1277	29	cells	cell	NNS
cord-022561-rv5j1201	1277	30	.	.	.
cord-022561-rv5j1201	1278	1	Chronic	Chronic	NNP
cord-022561-rv5j1201	1278	2	Lymphocytic	lymphocytic	JJ
cord-022561-rv5j1201	1278	3	Leukemia	Leukemia	NNP
cord-022561-rv5j1201	1278	4	.	.	.
cord-022561-rv5j1201	1279	1	Chronic	chronic	JJ
cord-022561-rv5j1201	1279	2	lymphocytic	lymphocytic	JJ
cord-022561-rv5j1201	1279	3	leukemia	leukemia	NN
cord-022561-rv5j1201	1279	4	(	(	-LRB-
cord-022561-rv5j1201	1279	5	CLL	CLL	NNP
cord-022561-rv5j1201	1279	6	)	)	-RRB-
cord-022561-rv5j1201	1279	7	is	be	VBZ
cord-022561-rv5j1201	1279	8	uncommon	uncommon	JJ
cord-022561-rv5j1201	1279	9	in	in	IN
cord-022561-rv5j1201	1279	10	veterinary	veterinary	JJ
cord-022561-rv5j1201	1279	11	medicine	medicine	NN
cord-022561-rv5j1201	1279	12	.	.	.
cord-022561-rv5j1201	1280	1	It	-PRON-	PRP
cord-022561-rv5j1201	1280	2	is	be	VBZ
cord-022561-rv5j1201	1280	3	predominantly	predominantly	RB
cord-022561-rv5j1201	1280	4	a	a	DT
cord-022561-rv5j1201	1280	5	disease	disease	NN
cord-022561-rv5j1201	1280	6	of	of	IN
cord-022561-rv5j1201	1280	7	middle	middle	NN
cord-022561-rv5j1201	1280	8	-	-	HYPH
cord-022561-rv5j1201	1280	9	aged	aged	JJ
cord-022561-rv5j1201	1280	10	to	to	IN
cord-022561-rv5j1201	1280	11	older	old	JJR
cord-022561-rv5j1201	1280	12	dogs	dog	NNS
cord-022561-rv5j1201	1280	13	but	but	CC
cord-022561-rv5j1201	1280	14	is	be	VBZ
cord-022561-rv5j1201	1280	15	also	also	RB
cord-022561-rv5j1201	1280	16	documented	document	VBN
cord-022561-rv5j1201	1280	17	in	in	IN
cord-022561-rv5j1201	1280	18	horses	horse	NNS
cord-022561-rv5j1201	1280	19	,	,	,
cord-022561-rv5j1201	1280	20	cattle	cattle	NNS
cord-022561-rv5j1201	1280	21	,	,	,
cord-022561-rv5j1201	1280	22	and	and	CC
cord-022561-rv5j1201	1280	23	cats	cat	NNS
cord-022561-rv5j1201	1280	24	.	.	.
cord-022561-rv5j1201	1281	1	Most	Most	JJS
cord-022561-rv5j1201	1281	2	canine	canine	JJ
cord-022561-rv5j1201	1281	3	chronic	chronic	NN
cord-022561-rv5j1201	1281	4	lymphocytic	lymphocytic	JJ
cord-022561-rv5j1201	1281	5	leukemia	leukemia	NN
cord-022561-rv5j1201	1281	6	cases	case	NNS
cord-022561-rv5j1201	1281	7	are	be	VBP
cord-022561-rv5j1201	1281	8	of	of	IN
cord-022561-rv5j1201	1281	9	T	T	NNP
cord-022561-rv5j1201	1281	10	lymphocyte	lymphocyte	NN
cord-022561-rv5j1201	1281	11	origin	origin	NN
cord-022561-rv5j1201	1281	12	,	,	,
cord-022561-rv5j1201	1281	13	typically	typically	RB
cord-022561-rv5j1201	1281	14	cytotoxic	cytotoxic	JJ
cord-022561-rv5j1201	1281	15	T	t	NN
cord-022561-rv5j1201	1281	16	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	1281	17	expressing	express	VBG
cord-022561-rv5j1201	1281	18	CD8	CD8	NNP
cord-022561-rv5j1201	1281	19	.	.	.
cord-022561-rv5j1201	1282	1	In	in	IN
cord-022561-rv5j1201	1282	2	cats	cat	NNS
cord-022561-rv5j1201	1282	3	the	the	DT
cord-022561-rv5j1201	1282	4	majority	majority	NN
cord-022561-rv5j1201	1282	5	of	of	IN
cord-022561-rv5j1201	1282	6	chronic	chronic	JJ
cord-022561-rv5j1201	1282	7	lymphocytic	lymphocytic	JJ
cord-022561-rv5j1201	1282	8	leukemia	leukemia	NN
cord-022561-rv5j1201	1282	9	cases	case	NNS
cord-022561-rv5j1201	1282	10	have	have	VBP
cord-022561-rv5j1201	1282	11	a	a	DT
cord-022561-rv5j1201	1282	12	T	t	NN
cord-022561-rv5j1201	1282	13	helper	helper	NN
cord-022561-rv5j1201	1282	14	lymphocyte	lymphocyte	NN
cord-022561-rv5j1201	1282	15	immunophenotype	immunophenotype	NN
cord-022561-rv5j1201	1282	16	.	.	.
cord-022561-rv5j1201	1283	1	A	a	DT
cord-022561-rv5j1201	1283	2	CBC	CBC	NNP
cord-022561-rv5j1201	1283	3	often	often	RB
cord-022561-rv5j1201	1283	4	shows	show	VBZ
cord-022561-rv5j1201	1283	5	very	very	RB
cord-022561-rv5j1201	1283	6	high	high	JJ
cord-022561-rv5j1201	1283	7	numbers	number	NNS
cord-022561-rv5j1201	1283	8	of	of	IN
cord-022561-rv5j1201	1283	9	small	small	JJ
cord-022561-rv5j1201	1283	10	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	1283	11	with	with	IN
cord-022561-rv5j1201	1283	12	clumped	clumped	JJ
cord-022561-rv5j1201	1283	13	chromatin	chromatin	NN
cord-022561-rv5j1201	1283	14	and	and	CC
cord-022561-rv5j1201	1283	15	scant	scant	JJ
cord-022561-rv5j1201	1283	16	cytoplasm	cytoplasm	NN
cord-022561-rv5j1201	1283	17	.	.	.
cord-022561-rv5j1201	1284	1	Proliferating	proliferate	VBG
cord-022561-rv5j1201	1284	2	cytotoxic	cytotoxic	JJ
cord-022561-rv5j1201	1284	3	T	t	NN
cord-022561-rv5j1201	1284	4	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	1284	5	frequently	frequently	RB
cord-022561-rv5j1201	1284	6	contain	contain	VBP
cord-022561-rv5j1201	1284	7	a	a	DT
cord-022561-rv5j1201	1284	8	few	few	JJ
cord-022561-rv5j1201	1284	9	pink	pink	JJ
cord-022561-rv5j1201	1284	10	cytoplasmic	cytoplasmic	JJ
cord-022561-rv5j1201	1284	11	granules	granule	NNS
cord-022561-rv5j1201	1284	12	when	when	WRB
cord-022561-rv5j1201	1284	13	stained	stain	VBN
cord-022561-rv5j1201	1284	14	with	with	IN
cord-022561-rv5j1201	1284	15	most	most	JJS
cord-022561-rv5j1201	1284	16	methanol	methanol	NN
cord-022561-rv5j1201	1284	17	-	-	HYPH
cord-022561-rv5j1201	1284	18	based	base	VBN
cord-022561-rv5j1201	1284	19	Romanowsky	Romanowsky	NNP
cord-022561-rv5j1201	1284	20	stains	stain	NNS
cord-022561-rv5j1201	1284	21	(	(	-LRB-
cord-022561-rv5j1201	1284	22	e.g.	e.g.	RB
cord-022561-rv5j1201	1284	23	,	,	,
cord-022561-rv5j1201	1284	24	Wright	Wright	NNP
cord-022561-rv5j1201	1284	25	-	-	HYPH
cord-022561-rv5j1201	1284	26	Giemsa	Giemsa	NNP
cord-022561-rv5j1201	1284	27	)	)	-RRB-
cord-022561-rv5j1201	1284	28	.	.	.
cord-022561-rv5j1201	1285	1	However	however	RB
cord-022561-rv5j1201	1285	2	,	,	,
cord-022561-rv5j1201	1285	3	these	these	DT
cord-022561-rv5j1201	1285	4	granules	granule	NNS
cord-022561-rv5j1201	1285	5	may	may	MD
cord-022561-rv5j1201	1285	6	not	not	RB
cord-022561-rv5j1201	1285	7	be	be	VB
cord-022561-rv5j1201	1285	8	appreciated	appreciate	VBN
cord-022561-rv5j1201	1285	9	with	with	IN
cord-022561-rv5j1201	1285	10	some	some	DT
cord-022561-rv5j1201	1285	11	aqueous	aqueous	NN
cord-022561-rv5j1201	1285	12	-	-	HYPH
cord-022561-rv5j1201	1285	13	based	base	VBN
cord-022561-rv5j1201	1285	14	Romanowsky	Romanowsky	NNP
cord-022561-rv5j1201	1285	15	stains	stain	NNS
cord-022561-rv5j1201	1285	16	(	(	-LRB-
cord-022561-rv5j1201	1285	17	e.g.	e.g.	RB
cord-022561-rv5j1201	1285	18	,	,	,
cord-022561-rv5j1201	1285	19	Diff	Diff	NNP
cord-022561-rv5j1201	1285	20	-	-	HYPH
cord-022561-rv5j1201	1285	21	Quik	Quik	NNP
cord-022561-rv5j1201	1285	22	)	)	-RRB-
cord-022561-rv5j1201	1285	23	.	.	.
cord-022561-rv5j1201	1286	1	Although	although	IN
cord-022561-rv5j1201	1286	2	the	the	DT
cord-022561-rv5j1201	1286	3	number	number	NN
cord-022561-rv5j1201	1286	4	of	of	IN
cord-022561-rv5j1201	1286	5	total	total	JJ
cord-022561-rv5j1201	1286	6	blood	blood	NN
cord-022561-rv5j1201	1286	7	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	1286	8	is	be	VBZ
cord-022561-rv5j1201	1286	9	often	often	RB
cord-022561-rv5j1201	1286	10	greater	great	JJR
cord-022561-rv5j1201	1286	11	than	than	IN
cord-022561-rv5j1201	1286	12	100,000/µL	100,000/µl	CD
cord-022561-rv5j1201	1286	13	,	,	,
cord-022561-rv5j1201	1286	14	relatively	relatively	RB
cord-022561-rv5j1201	1286	15	mild	mild	JJ
cord-022561-rv5j1201	1286	16	lymphocytosis	lymphocytosis	NN
cord-022561-rv5j1201	1286	17	(	(	-LRB-
cord-022561-rv5j1201	1286	18	e.g.	e.g.	RB
cord-022561-rv5j1201	1286	19	,	,	,
cord-022561-rv5j1201	1286	20	15,000/µL	15,000/µl	CD
cord-022561-rv5j1201	1286	21	)	)	-RRB-
cord-022561-rv5j1201	1286	22	has	have	VBZ
cord-022561-rv5j1201	1286	23	been	be	VBN
cord-022561-rv5j1201	1286	24	reported	report	VBN
cord-022561-rv5j1201	1286	25	.	.	.
cord-022561-rv5j1201	1287	1	Seventy	seventy	CD
cord-022561-rv5j1201	1287	2	-	-	HYPH
cord-022561-rv5j1201	1287	3	five	five	CD
cord-022561-rv5j1201	1287	4	percent	percent	NN
cord-022561-rv5j1201	1287	5	of	of	IN
cord-022561-rv5j1201	1287	6	affected	affect	VBN
cord-022561-rv5j1201	1287	7	dogs	dog	NNS
cord-022561-rv5j1201	1287	8	also	also	RB
cord-022561-rv5j1201	1287	9	have	have	VBP
cord-022561-rv5j1201	1287	10	often	often	RB
cord-022561-rv5j1201	1287	11	of	of	IN
cord-022561-rv5j1201	1287	12	eosinophilic	eosinophilic	JJ
cord-022561-rv5j1201	1287	13	or	or	CC
cord-022561-rv5j1201	1287	14	neutrophilic	neutrophilic	JJ
cord-022561-rv5j1201	1287	15	cell	cell	NN
cord-022561-rv5j1201	1287	16	lines	line	NNS
cord-022561-rv5j1201	1287	17	.	.	.
cord-022561-rv5j1201	1288	1	Although	although	IN
cord-022561-rv5j1201	1288	2	rare	rare	JJ
cord-022561-rv5j1201	1288	3	,	,	,
cord-022561-rv5j1201	1288	4	there	there	EX
cord-022561-rv5j1201	1288	5	are	be	VBP
cord-022561-rv5j1201	1288	6	reports	report	NNS
cord-022561-rv5j1201	1288	7	of	of	IN
cord-022561-rv5j1201	1288	8	granulocytic	granulocytic	JJ
cord-022561-rv5j1201	1288	9	sarcoma	sarcoma	NN
cord-022561-rv5j1201	1288	10	in	in	IN
cord-022561-rv5j1201	1288	11	dogs	dog	NNS
cord-022561-rv5j1201	1288	12	,	,	,
cord-022561-rv5j1201	1288	13	cats	cat	NNS
cord-022561-rv5j1201	1288	14	,	,	,
cord-022561-rv5j1201	1288	15	cattle	cattle	NNS
cord-022561-rv5j1201	1288	16	,	,	,
cord-022561-rv5j1201	1288	17	and	and	CC
cord-022561-rv5j1201	1288	18	pigs	pig	NNS
cord-022561-rv5j1201	1288	19	,	,	,
cord-022561-rv5j1201	1288	20	and	and	CC
cord-022561-rv5j1201	1288	21	it	-PRON-	PRP
cord-022561-rv5j1201	1288	22	may	may	MD
cord-022561-rv5j1201	1288	23	arise	arise	VB
cord-022561-rv5j1201	1288	24	in	in	IN
cord-022561-rv5j1201	1288	25	a	a	DT
cord-022561-rv5j1201	1288	26	number	number	NN
cord-022561-rv5j1201	1288	27	of	of	IN
cord-022561-rv5j1201	1288	28	sites	site	NNS
cord-022561-rv5j1201	1288	29	,	,	,
cord-022561-rv5j1201	1288	30	such	such	JJ
cord-022561-rv5j1201	1288	31	as	as	IN
cord-022561-rv5j1201	1288	32	lung	lung	NN
cord-022561-rv5j1201	1288	33	,	,	,
cord-022561-rv5j1201	1288	34	intestine	intestine	NN
cord-022561-rv5j1201	1288	35	,	,	,
cord-022561-rv5j1201	1288	36	lymph	lymph	NN
cord-022561-rv5j1201	1288	37	nodes	node	NNS
cord-022561-rv5j1201	1288	38	,	,	,
cord-022561-rv5j1201	1288	39	liver	liver	NN
cord-022561-rv5j1201	1288	40	,	,	,
cord-022561-rv5j1201	1288	41	kidney	kidney	NN
cord-022561-rv5j1201	1288	42	,	,	,
cord-022561-rv5j1201	1288	43	skin	skin	NN
cord-022561-rv5j1201	1288	44	,	,	,
cord-022561-rv5j1201	1288	45	and	and	CC
cord-022561-rv5j1201	1288	46	muscle	muscle	NN
cord-022561-rv5j1201	1288	47	.	.	.
cord-022561-rv5j1201	1289	1	Acute	acute	JJ
cord-022561-rv5j1201	1289	2	Lymphoblastic	Lymphoblastic	NNP
cord-022561-rv5j1201	1289	3	Leukemia	Leukemia	NNP
cord-022561-rv5j1201	1289	4	.	.	.
cord-022561-rv5j1201	1290	1	Acute	acute	JJ
cord-022561-rv5j1201	1290	2	lymphoblastic	lymphoblastic	JJ
cord-022561-rv5j1201	1290	3	leukemia	leukemia	NN
cord-022561-rv5j1201	1290	4	(	(	-LRB-
cord-022561-rv5j1201	1290	5	ALL	all	DT
cord-022561-rv5j1201	1290	6	)	)	-RRB-
cord-022561-rv5j1201	1290	7	is	be	VBZ
cord-022561-rv5j1201	1290	8	uncommon	uncommon	JJ
cord-022561-rv5j1201	1290	9	in	in	IN
cord-022561-rv5j1201	1290	10	dogs	dog	NNS
cord-022561-rv5j1201	1290	11	and	and	CC
cord-022561-rv5j1201	1290	12	cats	cat	NNS
cord-022561-rv5j1201	1290	13	,	,	,
cord-022561-rv5j1201	1290	14	and	and	CC
cord-022561-rv5j1201	1290	15	rare	rare	JJ
cord-022561-rv5j1201	1290	16	in	in	IN
cord-022561-rv5j1201	1290	17	horses	horse	NNS
cord-022561-rv5j1201	1290	18	and	and	CC
cord-022561-rv5j1201	1290	19	cattle	cattle	NNS
cord-022561-rv5j1201	1290	20	.	.	.
cord-022561-rv5j1201	1291	1	In	in	IN
cord-022561-rv5j1201	1291	2	a	a	DT
cord-022561-rv5j1201	1291	3	recent	recent	JJ
cord-022561-rv5j1201	1291	4	immunophenotype	immunophenotype	NN
cord-022561-rv5j1201	1291	5	study	study	NN
cord-022561-rv5j1201	1291	6	of	of	IN
cord-022561-rv5j1201	1291	7	51	51	CD
cord-022561-rv5j1201	1291	8	cases	case	NNS
cord-022561-rv5j1201	1291	9	of	of	IN
cord-022561-rv5j1201	1291	10	acute	acute	JJ
cord-022561-rv5j1201	1291	11	lymphoblastic	lymphoblastic	JJ
cord-022561-rv5j1201	1291	12	leukemia	leukemia	NN
cord-022561-rv5j1201	1291	13	in	in	IN
cord-022561-rv5j1201	1291	14	dogs	dog	NNS
cord-022561-rv5j1201	1291	15	,	,	,
cord-022561-rv5j1201	1291	16	47	47	CD
cord-022561-rv5j1201	1291	17	arose	arise	VBD
cord-022561-rv5j1201	1291	18	from	from	IN
cord-022561-rv5j1201	1291	19	B	b	NN
cord-022561-rv5j1201	1291	20	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	1291	21	and	and	CC
cord-022561-rv5j1201	1291	22	4	4	CD
cord-022561-rv5j1201	1291	23	arose	arise	VBD
cord-022561-rv5j1201	1291	24	from	from	IN
cord-022561-rv5j1201	1291	25	double	double	JJ
cord-022561-rv5j1201	1291	26	-	-	HYPH
cord-022561-rv5j1201	1291	27	negative	negative	JJ
cord-022561-rv5j1201	1291	28	T	t	NN
cord-022561-rv5j1201	1291	29	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	1291	30	that	that	WDT
cord-022561-rv5j1201	1291	31	were	be	VBD
cord-022561-rv5j1201	1291	32	immunonegative	immunonegative	JJ
cord-022561-rv5j1201	1291	33	for	for	IN
cord-022561-rv5j1201	1291	34	CD4	CD4	NNP
cord-022561-rv5j1201	1291	35	and	and	CC
cord-022561-rv5j1201	1291	36	CD8	CD8	NNP
cord-022561-rv5j1201	1291	37	markers	marker	NNS
cord-022561-rv5j1201	1291	38	.	.	.
cord-022561-rv5j1201	1292	1	In	in	IN
cord-022561-rv5j1201	1292	2	the	the	DT
cord-022561-rv5j1201	1292	3	blood	blood	NN
cord-022561-rv5j1201	1292	4	of	of	IN
cord-022561-rv5j1201	1292	5	animals	animal	NNS
cord-022561-rv5j1201	1292	6	with	with	IN
cord-022561-rv5j1201	1292	7	acute	acute	JJ
cord-022561-rv5j1201	1292	8	lymphoblastic	lymphoblastic	JJ
cord-022561-rv5j1201	1292	9	leukemia	leukemia	NN
cord-022561-rv5j1201	1292	10	,	,	,
cord-022561-rv5j1201	1292	11	there	there	EX
cord-022561-rv5j1201	1292	12	are	be	VBP
cord-022561-rv5j1201	1292	13	typically	typically	RB
cord-022561-rv5j1201	1292	14	many	many	JJ
cord-022561-rv5j1201	1292	15	medium	medium	NN
cord-022561-rv5j1201	1292	16	to	to	IN
cord-022561-rv5j1201	1292	17	large	large	JJ
cord-022561-rv5j1201	1292	18	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	1292	19	cells	cell	NNS
cord-022561-rv5j1201	1292	20	with	with	IN
cord-022561-rv5j1201	1292	21	deeply	deeply	RB
cord-022561-rv5j1201	1292	22	basophilic	basophilic	JJ
cord-022561-rv5j1201	1292	23	cytoplasm	cytoplasm	NN
cord-022561-rv5j1201	1292	24	,	,	,
cord-022561-rv5j1201	1292	25	reticular	reticular	JJ
cord-022561-rv5j1201	1292	26	to	to	IN
cord-022561-rv5j1201	1292	27	coarse	coarse	JJ
cord-022561-rv5j1201	1292	28	chromatin	chromatin	NN
cord-022561-rv5j1201	1292	29	,	,	,
cord-022561-rv5j1201	1292	30	and	and	CC
cord-022561-rv5j1201	1292	31	prominent	prominent	JJ
cord-022561-rv5j1201	1292	32	,	,	,
cord-022561-rv5j1201	1292	33	multiple	multiple	JJ
cord-022561-rv5j1201	1292	34	nucleoli	nucleolus	NNS
cord-022561-rv5j1201	1292	35	(	(	-LRB-
cord-022561-rv5j1201	1292	36	see	see	VB
cord-022561-rv5j1201	1292	37	Fig	Fig	NNP
cord-022561-rv5j1201	1292	38	.	.	.
cord-022561-rv5j1201	1293	1	13	13	CD
cord-022561-rv5j1201	1293	2	-	-	SYM
cord-022561-rv5j1201	1293	3	31	31	CD
cord-022561-rv5j1201	1293	4	,	,	,
cord-022561-rv5j1201	1293	5	C	C	NNP
cord-022561-rv5j1201	1293	6	)	)	-RRB-
cord-022561-rv5j1201	1293	7	.	.	.
cord-022561-rv5j1201	1294	1	In	in	IN
cord-022561-rv5j1201	1294	2	affected	affected	JJ
cord-022561-rv5j1201	1294	3	dogs	dog	NNS
cord-022561-rv5j1201	1294	4	the	the	DT
cord-022561-rv5j1201	1294	5	mean	mean	JJ
cord-022561-rv5j1201	1294	6	blood	blood	NN
cord-022561-rv5j1201	1294	7	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	1294	8	concentration	concentration	NN
cord-022561-rv5j1201	1294	9	is	be	VBZ
cord-022561-rv5j1201	1294	10	approximately	approximately	RB
cord-022561-rv5j1201	1294	11	70,000/µL	70,000/µl	CD
cord-022561-rv5j1201	1294	12	,	,	,
cord-022561-rv5j1201	1294	13	but	but	CC
cord-022561-rv5j1201	1294	14	cats	cat	NNS
cord-022561-rv5j1201	1294	15	with	with	IN
cord-022561-rv5j1201	1294	16	acute	acute	JJ
cord-022561-rv5j1201	1294	17	lymphoblastic	lymphoblastic	JJ
cord-022561-rv5j1201	1294	18	leukemia	leukemia	NN
cord-022561-rv5j1201	1294	19	often	often	RB
cord-022561-rv5j1201	1294	20	have	have	VBP
cord-022561-rv5j1201	1294	21	low	low	JJ
cord-022561-rv5j1201	1294	22	numbers	number	NNS
cord-022561-rv5j1201	1294	23	of	of	IN
cord-022561-rv5j1201	1294	24	neoplastic	neoplastic	JJ
cord-022561-rv5j1201	1294	25	cells	cell	NNS
cord-022561-rv5j1201	1294	26	in	in	IN
cord-022561-rv5j1201	1294	27	the	the	DT
cord-022561-rv5j1201	1294	28	circulation	circulation	NN
cord-022561-rv5j1201	1294	29	.	.	.
cord-022561-rv5j1201	1295	1	As	as	IN
cord-022561-rv5j1201	1295	2	with	with	IN
cord-022561-rv5j1201	1295	3	animals	animal	NNS
cord-022561-rv5j1201	1295	4	with	with	IN
cord-022561-rv5j1201	1295	5	acute	acute	JJ
cord-022561-rv5j1201	1295	6	myeloid	myeloid	NN
cord-022561-rv5j1201	1295	7	leukemia	leukemia	NN
cord-022561-rv5j1201	1295	8	,	,	,
cord-022561-rv5j1201	1295	9	anemia	anemia	NN
cord-022561-rv5j1201	1295	10	,	,	,
cord-022561-rv5j1201	1295	11	neutropenia	neutropenia	NN
cord-022561-rv5j1201	1295	12	,	,	,
cord-022561-rv5j1201	1295	13	and	and	CC
cord-022561-rv5j1201	1295	14	C	c	NN
cord-022561-rv5j1201	1295	15	D	d	NN
cord-022561-rv5j1201	1295	16	m	m	NN
cord-022561-rv5j1201	1295	17	the	the	DT
cord-022561-rv5j1201	1295	18	light	light	JJ
cord-022561-rv5j1201	1295	19	chains	chain	NNS
cord-022561-rv5j1201	1295	20	deposit	deposit	VBP
cord-022561-rv5j1201	1295	21	as	as	IN
cord-022561-rv5j1201	1295	22	nonamyloid	nonamyloid	NNP
cord-022561-rv5j1201	1295	23	granules	granules	NNP
cord-022561-rv5j1201	1295	24	,	,	,
cord-022561-rv5j1201	1295	25	it	-PRON-	PRP
cord-022561-rv5j1201	1295	26	is	be	VBZ
cord-022561-rv5j1201	1295	27	termed	term	VBN
cord-022561-rv5j1201	1295	28	light	light	JJ
cord-022561-rv5j1201	1295	29	chain	chain	NN
cord-022561-rv5j1201	1295	30	deposition	deposition	NN
cord-022561-rv5j1201	1295	31	disease	disease	NN
cord-022561-rv5j1201	1295	32	.	.	.
cord-022561-rv5j1201	1296	1	Light	light	JJ
cord-022561-rv5j1201	1296	2	chains	chain	NNS
cord-022561-rv5j1201	1296	3	are	be	VBP
cord-022561-rv5j1201	1296	4	low	low	JJ
cord-022561-rv5j1201	1296	5	-	-	HYPH
cord-022561-rv5j1201	1296	6	molecular	molecular	JJ
cord-022561-rv5j1201	1296	7	-	-	HYPH
cord-022561-rv5j1201	1296	8	weight	weight	NN
cord-022561-rv5j1201	1296	9	proteins	protein	NNS
cord-022561-rv5j1201	1296	10	that	that	WDT
cord-022561-rv5j1201	1296	11	pass	pass	VBP
cord-022561-rv5j1201	1296	12	through	through	IN
cord-022561-rv5j1201	1296	13	the	the	DT
cord-022561-rv5j1201	1296	14	glomerular	glomerular	JJ
cord-022561-rv5j1201	1296	15	filter	filter	NN
cord-022561-rv5j1201	1296	16	into	into	IN
cord-022561-rv5j1201	1296	17	the	the	DT
cord-022561-rv5j1201	1296	18	urine	urine	NN
cord-022561-rv5j1201	1296	19	,	,	,
cord-022561-rv5j1201	1296	20	wherein	wherein	WRB
cord-022561-rv5j1201	1296	21	they	-PRON-	PRP
cord-022561-rv5j1201	1296	22	are	be	VBP
cord-022561-rv5j1201	1296	23	also	also	RB
cord-022561-rv5j1201	1296	24	known	know	VBN
cord-022561-rv5j1201	1296	25	as	as	IN
cord-022561-rv5j1201	1296	26	Bence	Bence	NNP
cord-022561-rv5j1201	1296	27	Jones	Jones	NNP
cord-022561-rv5j1201	1296	28	proteins	protein	NNS
cord-022561-rv5j1201	1296	29	.	.	.
cord-022561-rv5j1201	1297	1	They	-PRON-	PRP
cord-022561-rv5j1201	1297	2	tend	tend	VBP
cord-022561-rv5j1201	1297	3	to	to	TO
cord-022561-rv5j1201	1297	4	not	not	RB
cord-022561-rv5j1201	1297	5	react	react	VB
cord-022561-rv5j1201	1297	6	with	with	IN
cord-022561-rv5j1201	1297	7	urine	urine	NN
cord-022561-rv5j1201	1297	8	dipstick	dipstick	NN
cord-022561-rv5j1201	1297	9	protein	protein	NN
cord-022561-rv5j1201	1297	10	indicators	indicator	NNS
cord-022561-rv5j1201	1297	11	and	and	CC
cord-022561-rv5j1201	1297	12	are	be	VBP
cord-022561-rv5j1201	1297	13	most	most	RBS
cord-022561-rv5j1201	1297	14	specifically	specifically	RB
cord-022561-rv5j1201	1297	15	detected	detect	VBN
cord-022561-rv5j1201	1297	16	by	by	IN
cord-022561-rv5j1201	1297	17	electrophoresis	electrophoresis	NN
cord-022561-rv5j1201	1297	18	and	and	CC
cord-022561-rv5j1201	1297	19	immunoprecipitation	immunoprecipitation	NN
cord-022561-rv5j1201	1297	20	.	.	.
cord-022561-rv5j1201	1298	1	In	in	IN
cord-022561-rv5j1201	1298	2	addition	addition	NN
cord-022561-rv5j1201	1298	3	to	to	IN
cord-022561-rv5j1201	1298	4	aiding	aid	VBG
cord-022561-rv5j1201	1298	5	in	in	IN
cord-022561-rv5j1201	1298	6	the	the	DT
cord-022561-rv5j1201	1298	7	diagnosis	diagnosis	NN
cord-022561-rv5j1201	1298	8	of	of	IN
cord-022561-rv5j1201	1298	9	multiple	multiple	JJ
cord-022561-rv5j1201	1298	10	myeloma	myeloma	NN
cord-022561-rv5j1201	1298	11	,	,	,
cord-022561-rv5j1201	1298	12	paraproteins	paraprotein	NNS
cord-022561-rv5j1201	1298	13	have	have	VBP
cord-022561-rv5j1201	1298	14	an	an	DT
cord-022561-rv5j1201	1298	15	important	important	JJ
cord-022561-rv5j1201	1298	16	role	role	NN
cord-022561-rv5j1201	1298	17	in	in	IN
cord-022561-rv5j1201	1298	18	pathogenesis	pathogenesis	NN
cord-022561-rv5j1201	1298	19	of	of	IN
cord-022561-rv5j1201	1298	20	disease	disease	NN
cord-022561-rv5j1201	1298	21	.	.	.
cord-022561-rv5j1201	1299	1	These	these	DT
cord-022561-rv5j1201	1299	2	proteins	protein	NNS
cord-022561-rv5j1201	1299	3	may	may	MD
cord-022561-rv5j1201	1299	4	inhibit	inhibit	VB
cord-022561-rv5j1201	1299	5	platelet	platelet	NN
cord-022561-rv5j1201	1299	6	function	function	NN
cord-022561-rv5j1201	1299	7	,	,	,
cord-022561-rv5j1201	1299	8	increase	increase	VB
cord-022561-rv5j1201	1299	9	blood	blood	NN
cord-022561-rv5j1201	1299	10	viscosity	viscosity	NN
cord-022561-rv5j1201	1299	11	,	,	,
cord-022561-rv5j1201	1299	12	deposit	deposit	NN
cord-022561-rv5j1201	1299	13	in	in	IN
cord-022561-rv5j1201	1299	14	glomerular	glomerular	JJ
cord-022561-rv5j1201	1299	15	basement	basement	NN
cord-022561-rv5j1201	1299	16	membranes	membrane	NNS
cord-022561-rv5j1201	1299	17	(	(	-LRB-
cord-022561-rv5j1201	1299	18	see	see	VB
cord-022561-rv5j1201	1299	19	Chapter	chapter	NN
cord-022561-rv5j1201	1299	20	11	11	CD
cord-022561-rv5j1201	1299	21	;	;	:
cord-022561-rv5j1201	1299	22	see	see	VB
cord-022561-rv5j1201	1299	23	Figs	fig	NNS
cord-022561-rv5j1201	1299	24	.	.	.
cord-022561-rv5j1201	1300	1	11	11	CD
cord-022561-rv5j1201	1300	2	-	-	SYM
cord-022561-rv5j1201	1300	3	27	27	CD
cord-022561-rv5j1201	1300	4	and	and	CC
cord-022561-rv5j1201	1300	5	11	11	CD
cord-022561-rv5j1201	1300	6	-	-	SYM
cord-022561-rv5j1201	1300	7	28	28	CD
cord-022561-rv5j1201	1300	8	,	,	,
cord-022561-rv5j1201	1300	9	or	or	CC
cord-022561-rv5j1201	1300	10	precipitate	precipitate	VB
cord-022561-rv5j1201	1300	11	at	at	IN
cord-022561-rv5j1201	1300	12	cool	cool	JJ
cord-022561-rv5j1201	1300	13	temperatures	temperature	NNS
cord-022561-rv5j1201	1300	14	,	,	,
cord-022561-rv5j1201	1300	15	which	which	WDT
cord-022561-rv5j1201	1300	16	results	result	VBZ
cord-022561-rv5j1201	1300	17	in	in	IN
cord-022561-rv5j1201	1300	18	bleeding	bleed	VBG
cord-022561-rv5j1201	1300	19	tendencies	tendency	NNS
cord-022561-rv5j1201	1300	20	,	,	,
cord-022561-rv5j1201	1300	21	hyperviscosity	hyperviscosity	NN
cord-022561-rv5j1201	1300	22	syndrome	syndrome	NN
cord-022561-rv5j1201	1300	23	,	,	,
cord-022561-rv5j1201	1300	24	glomerulopathies	glomerulopathie	NNS
cord-022561-rv5j1201	1300	25	,	,	,
cord-022561-rv5j1201	1300	26	and	and	CC
cord-022561-rv5j1201	1300	27	cryoglobulinemia	cryoglobulinemia	NN
cord-022561-rv5j1201	1300	28	,	,	,
cord-022561-rv5j1201	1300	29	respectively	respectively	RB
cord-022561-rv5j1201	1300	30	.	.	.
cord-022561-rv5j1201	1301	1	Hyperviscosity	Hyperviscosity	NNP
cord-022561-rv5j1201	1301	2	syndrome	syndrome	NN
cord-022561-rv5j1201	1301	3	refers	refer	VBZ
cord-022561-rv5j1201	1301	4	to	to	IN
cord-022561-rv5j1201	1301	5	the	the	DT
cord-022561-rv5j1201	1301	6	clinical	clinical	JJ
cord-022561-rv5j1201	1301	7	sequelae	sequela	NNS
cord-022561-rv5j1201	1301	8	of	of	IN
cord-022561-rv5j1201	1301	9	pathologically	pathologically	RB
cord-022561-rv5j1201	1301	10	increased	increase	VBN
cord-022561-rv5j1201	1301	11	blood	blood	NN
cord-022561-rv5j1201	1301	12	viscosity	viscosity	NN
cord-022561-rv5j1201	1301	13	,	,	,
cord-022561-rv5j1201	1301	14	which	which	WDT
cord-022561-rv5j1201	1301	15	are	be	VBP
cord-022561-rv5j1201	1301	16	slowed	slow	VBN
cord-022561-rv5j1201	1301	17	blood	blood	NN
cord-022561-rv5j1201	1301	18	flow	flow	NN
cord-022561-rv5j1201	1301	19	and	and	CC
cord-022561-rv5j1201	1301	20	loss	loss	NN
cord-022561-rv5j1201	1301	21	of	of	IN
cord-022561-rv5j1201	1301	22	laminar	laminar	JJ
cord-022561-rv5j1201	1301	23	flow	flow	NN
cord-022561-rv5j1201	1301	24	.	.	.
cord-022561-rv5j1201	1302	1	Clinical	clinical	JJ
cord-022561-rv5j1201	1302	2	signs	sign	NNS
cord-022561-rv5j1201	1302	3	include	include	VBP
cord-022561-rv5j1201	1302	4	mucosal	mucosal	JJ
cord-022561-rv5j1201	1302	5	hemorrhages	hemorrhage	NNS
cord-022561-rv5j1201	1302	6	,	,	,
cord-022561-rv5j1201	1302	7	visual	visual	JJ
cord-022561-rv5j1201	1302	8	impairment	impairment	NN
cord-022561-rv5j1201	1302	9	due	due	IN
cord-022561-rv5j1201	1302	10	to	to	IN
cord-022561-rv5j1201	1302	11	retinopathy	retinopathy	NN
cord-022561-rv5j1201	1302	12	,	,	,
cord-022561-rv5j1201	1302	13	and	and	CC
cord-022561-rv5j1201	1302	14	neurologic	neurologic	JJ
cord-022561-rv5j1201	1302	15	signs	sign	NNS
cord-022561-rv5j1201	1302	16	,	,	,
cord-022561-rv5j1201	1302	17	such	such	JJ
cord-022561-rv5j1201	1302	18	as	as	IN
cord-022561-rv5j1201	1302	19	tremors	tremor	NNS
cord-022561-rv5j1201	1302	20	and	and	CC
cord-022561-rv5j1201	1302	21	abnormal	abnormal	JJ
cord-022561-rv5j1201	1302	22	aggressive	aggressive	JJ
cord-022561-rv5j1201	1302	23	behavior	behavior	NN
cord-022561-rv5j1201	1302	24	.	.	.
cord-022561-rv5j1201	1303	1	Cryoglobulinemia	Cryoglobulinemia	NNP
cord-022561-rv5j1201	1303	2	is	be	VBZ
cord-022561-rv5j1201	1303	3	the	the	DT
cord-022561-rv5j1201	1303	4	condition	condition	NN
cord-022561-rv5j1201	1303	5	in	in	IN
cord-022561-rv5j1201	1303	6	which	which	WDT
cord-022561-rv5j1201	1303	7	proteins	protein	NNS
cord-022561-rv5j1201	1303	8	,	,	,
cord-022561-rv5j1201	1303	9	typically	typically	RB
cord-022561-rv5j1201	1303	10	IgM	IgM	NNP
cord-022561-rv5j1201	1303	11	,	,	,
cord-022561-rv5j1201	1303	12	precipitate	precipitate	VBP
cord-022561-rv5j1201	1303	13	at	at	IN
cord-022561-rv5j1201	1303	14	temperatures	temperature	NNS
cord-022561-rv5j1201	1303	15	below	below	IN
cord-022561-rv5j1201	1303	16	normal	normal	JJ
cord-022561-rv5j1201	1303	17	body	body	NN
cord-022561-rv5j1201	1303	18	temperature	temperature	NN
cord-022561-rv5j1201	1303	19	(	(	-LRB-
cord-022561-rv5j1201	1303	20	cold	cold	JJ
cord-022561-rv5j1201	1303	21	agglutinins	agglutinin	NNS
cord-022561-rv5j1201	1303	22	)	)	-RRB-
cord-022561-rv5j1201	1303	23	.	.	.
cord-022561-rv5j1201	1304	1	Precipitation	precipitation	NN
cord-022561-rv5j1201	1304	2	often	often	RB
cord-022561-rv5j1201	1304	3	occurs	occur	VBZ
cord-022561-rv5j1201	1304	4	in	in	IN
cord-022561-rv5j1201	1304	5	blood	blood	NN
cord-022561-rv5j1201	1304	6	vessels	vessel	NNS
cord-022561-rv5j1201	1304	7	of	of	IN
cord-022561-rv5j1201	1304	8	the	the	DT
cord-022561-rv5j1201	1304	9	skin	skin	NN
cord-022561-rv5j1201	1304	10	and	and	CC
cord-022561-rv5j1201	1304	11	extremities	extremity	NNS
cord-022561-rv5j1201	1304	12	,	,	,
cord-022561-rv5j1201	1304	13	such	such	JJ
cord-022561-rv5j1201	1304	14	as	as	IN
cord-022561-rv5j1201	1304	15	the	the	DT
cord-022561-rv5j1201	1304	16	ears	ear	NNS
cord-022561-rv5j1201	1304	17	and	and	CC
cord-022561-rv5j1201	1304	18	digits	digit	NNS
cord-022561-rv5j1201	1304	19	,	,	,
cord-022561-rv5j1201	1304	20	and	and	CC
cord-022561-rv5j1201	1304	21	results	result	NNS
cord-022561-rv5j1201	1304	22	in	in	IN
cord-022561-rv5j1201	1304	23	ischemic	ischemic	JJ
cord-022561-rv5j1201	1304	24	necrosis	necrosis	NN
cord-022561-rv5j1201	1304	25	.	.	.
cord-022561-rv5j1201	1305	1	In	in	IN
cord-022561-rv5j1201	1305	2	multiple	multiple	JJ
cord-022561-rv5j1201	1305	3	myeloma	myeloma	NN
cord-022561-rv5j1201	1305	4	the	the	DT
cord-022561-rv5j1201	1305	5	neoplastic	neoplastic	JJ
cord-022561-rv5j1201	1305	6	proliferation	proliferation	NN
cord-022561-rv5j1201	1305	7	of	of	IN
cord-022561-rv5j1201	1305	8	plasma	plasma	NN
cord-022561-rv5j1201	1305	9	cells	cell	NNS
cord-022561-rv5j1201	1305	10	results	result	NNS
cord-022561-rv5j1201	1305	11	in	in	IN
cord-022561-rv5j1201	1305	12	osteolysis	osteolysis	NN
cord-022561-rv5j1201	1305	13	.	.	.
cord-022561-rv5j1201	1306	1	Work	work	VB
cord-022561-rv5j1201	1306	2	with	with	IN
cord-022561-rv5j1201	1306	3	human	human	JJ
cord-022561-rv5j1201	1306	4	cell	cell	NN
cord-022561-rv5j1201	1306	5	cultures	culture	NNS
cord-022561-rv5j1201	1306	6	has	have	VBZ
cord-022561-rv5j1201	1306	7	shown	show	VBN
cord-022561-rv5j1201	1306	8	that	that	DT
cord-022561-rv5j1201	1306	9	anemia	anemia	NN
cord-022561-rv5j1201	1306	10	,	,	,
cord-022561-rv5j1201	1306	11	and	and	CC
cord-022561-rv5j1201	1306	12	15	15	CD
cord-022561-rv5j1201	1306	13	%	%	NN
cord-022561-rv5j1201	1306	14	have	have	VBP
cord-022561-rv5j1201	1306	15	thrombocytopenia	thrombocytopenia	NN
cord-022561-rv5j1201	1306	16	.	.	.
cord-022561-rv5j1201	1307	1	Autopsy	autopsy	JJ
cord-022561-rv5j1201	1307	2	findings	finding	NNS
cord-022561-rv5j1201	1307	3	depend	depend	VBP
cord-022561-rv5j1201	1307	4	on	on	IN
cord-022561-rv5j1201	1307	5	the	the	DT
cord-022561-rv5j1201	1307	6	stage	stage	NN
cord-022561-rv5j1201	1307	7	of	of	IN
cord-022561-rv5j1201	1307	8	disease	disease	NN
cord-022561-rv5j1201	1307	9	.	.	.
cord-022561-rv5j1201	1308	1	In	in	IN
cord-022561-rv5j1201	1308	2	advanced	advanced	JJ
cord-022561-rv5j1201	1308	3	cases	case	NNS
cord-022561-rv5j1201	1308	4	with	with	IN
cord-022561-rv5j1201	1308	5	marked	marked	JJ
cord-022561-rv5j1201	1308	6	infiltration	infiltration	NN
cord-022561-rv5j1201	1308	7	of	of	IN
cord-022561-rv5j1201	1308	8	organs	organ	NNS
cord-022561-rv5j1201	1308	9	with	with	IN
cord-022561-rv5j1201	1308	10	neoplastic	neoplastic	JJ
cord-022561-rv5j1201	1308	11	cells	cell	NNS
cord-022561-rv5j1201	1308	12	,	,	,
cord-022561-rv5j1201	1308	13	there	there	EX
cord-022561-rv5j1201	1308	14	is	be	VBZ
cord-022561-rv5j1201	1308	15	often	often	RB
cord-022561-rv5j1201	1308	16	uniform	uniform	JJ
cord-022561-rv5j1201	1308	17	splenomegaly	splenomegaly	NN
cord-022561-rv5j1201	1308	18	,	,	,
cord-022561-rv5j1201	1308	19	hepatomegaly	hepatomegaly	NNP
cord-022561-rv5j1201	1308	20	,	,	,
cord-022561-rv5j1201	1308	21	and	and	CC
cord-022561-rv5j1201	1308	22	lymphadenomegaly	lymphadenomegaly	NNP
cord-022561-rv5j1201	1308	23	,	,	,
cord-022561-rv5j1201	1308	24	and	and	CC
cord-022561-rv5j1201	1308	25	the	the	DT
cord-022561-rv5j1201	1308	26	bone	bone	NN
cord-022561-rv5j1201	1308	27	marrow	marrow	NN
cord-022561-rv5j1201	1308	28	is	be	VBZ
cord-022561-rv5j1201	1308	29	highly	highly	RB
cord-022561-rv5j1201	1308	30	cellular	cellular	JJ
cord-022561-rv5j1201	1309	1	(	(	-LRB-
cord-022561-rv5j1201	1309	2	E-	E-	NNP
cord-022561-rv5j1201	1309	3	Fig	Fig	NNP
cord-022561-rv5j1201	1309	4	.	.	.
cord-022561-rv5j1201	1310	1	13	13	CD
cord-022561-rv5j1201	1310	2	-	-	SYM
cord-022561-rv5j1201	1310	3	7	7	CD
cord-022561-rv5j1201	1310	4	;	;	:
cord-022561-rv5j1201	1310	5	see	see	VB
cord-022561-rv5j1201	1310	6	Fig	Fig	NNP
cord-022561-rv5j1201	1310	7	.	.	.
cord-022561-rv5j1201	1311	1	13	13	CD
cord-022561-rv5j1201	1311	2	-	-	SYM
cord-022561-rv5j1201	1311	3	31	31	CD
cord-022561-rv5j1201	1311	4	,	,	,
cord-022561-rv5j1201	1311	5	D	D	NNP
cord-022561-rv5j1201	1311	6	)	)	-RRB-
cord-022561-rv5j1201	1311	7	.	.	.
cord-022561-rv5j1201	1312	1	Other	other	JJ
cord-022561-rv5j1201	1312	2	lesions	lesion	NNS
cord-022561-rv5j1201	1312	3	depend	depend	VBP
cord-022561-rv5j1201	1312	4	on	on	IN
cord-022561-rv5j1201	1312	5	whether	whether	IN
cord-022561-rv5j1201	1312	6	there	there	EX
cord-022561-rv5j1201	1312	7	are	be	VBP
cord-022561-rv5j1201	1312	8	concurrent	concurrent	JJ
cord-022561-rv5j1201	1312	9	cytopenias	cytopenia	NNS
cord-022561-rv5j1201	1312	10	,	,	,
cord-022561-rv5j1201	1312	11	such	such	JJ
cord-022561-rv5j1201	1312	12	as	as	IN
cord-022561-rv5j1201	1312	13	anemia	anemia	NN
cord-022561-rv5j1201	1312	14	,	,	,
cord-022561-rv5j1201	1312	15	neutropenia	neutropenia	NN
cord-022561-rv5j1201	1312	16	,	,	,
cord-022561-rv5j1201	1312	17	and	and	CC
cord-022561-rv5j1201	1312	18	thrombocytopenia	thrombocytopenia	NN
cord-022561-rv5j1201	1312	19	,	,	,
cord-022561-rv5j1201	1312	20	and	and	CC
cord-022561-rv5j1201	1312	21	if	if	IN
cord-022561-rv5j1201	1312	22	the	the	DT
cord-022561-rv5j1201	1312	23	neoplastic	neoplastic	JJ
cord-022561-rv5j1201	1312	24	cells	cell	NNS
cord-022561-rv5j1201	1312	25	produce	produce	VBP
cord-022561-rv5j1201	1312	26	excessive	excessive	JJ
cord-022561-rv5j1201	1312	27	immunoglobulin	immunoglobulin	NN
cord-022561-rv5j1201	1312	28	.	.	.
cord-022561-rv5j1201	1313	1	Lesions	lesion	NNS
cord-022561-rv5j1201	1313	2	caused	cause	VBN
cord-022561-rv5j1201	1313	3	by	by	IN
cord-022561-rv5j1201	1313	4	excessive	excessive	JJ
cord-022561-rv5j1201	1313	5	immunoglobulin	immunoglobulin	NN
cord-022561-rv5j1201	1313	6	are	be	VBP
cord-022561-rv5j1201	1313	7	further	further	RB
cord-022561-rv5j1201	1313	8	discussed	discuss	VBN
cord-022561-rv5j1201	1313	9	in	in	IN
cord-022561-rv5j1201	1313	10	the	the	DT
cord-022561-rv5j1201	1313	11	section	section	NN
cord-022561-rv5j1201	1313	12	on	on	IN
cord-022561-rv5j1201	1313	13	multiple	multiple	JJ
cord-022561-rv5j1201	1313	14	myeloma	myeloma	NN
cord-022561-rv5j1201	1313	15	.	.	.
cord-022561-rv5j1201	1314	1	Histologically	histologically	RB
cord-022561-rv5j1201	1314	2	,	,	,
cord-022561-rv5j1201	1314	3	the	the	DT
cord-022561-rv5j1201	1314	4	bone	bone	NN
cord-022561-rv5j1201	1314	5	marrow	marrow	NN
cord-022561-rv5j1201	1314	6	is	be	VBZ
cord-022561-rv5j1201	1314	7	densely	densely	RB
cord-022561-rv5j1201	1314	8	cellular	cellular	JJ
cord-022561-rv5j1201	1314	9	with	with	IN
cord-022561-rv5j1201	1314	10	welldifferentiated	welldifferentiated	JJ
cord-022561-rv5j1201	1314	11	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	1314	12	.	.	.
cord-022561-rv5j1201	1315	1	Small	small	JJ
cord-022561-rv5j1201	1315	2	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	1315	3	infiltrate	infiltrate	VBP
cord-022561-rv5j1201	1315	4	and	and	CC
cord-022561-rv5j1201	1315	5	often	often	RB
cord-022561-rv5j1201	1315	6	efface	efface	VB
cord-022561-rv5j1201	1315	7	in	in	IN
cord-022561-rv5j1201	1315	8	the	the	DT
cord-022561-rv5j1201	1315	9	architecture	architecture	NN
cord-022561-rv5j1201	1315	10	of	of	IN
cord-022561-rv5j1201	1315	11	the	the	DT
cord-022561-rv5j1201	1315	12	lymph	lymph	NN
cord-022561-rv5j1201	1315	13	nodes	node	NNS
cord-022561-rv5j1201	1315	14	and	and	CC
cord-022561-rv5j1201	1315	15	spleen	spleen	NNS
cord-022561-rv5j1201	1315	16	.	.	.
cord-022561-rv5j1201	1316	1	The	the	DT
cord-022561-rv5j1201	1316	2	liver	liver	NN
cord-022561-rv5j1201	1316	3	may	may	MD
cord-022561-rv5j1201	1316	4	have	have	VB
cord-022561-rv5j1201	1316	5	dense	dense	JJ
cord-022561-rv5j1201	1316	6	accumulations	accumulation	NNS
cord-022561-rv5j1201	1316	7	of	of	IN
cord-022561-rv5j1201	1316	8	neoplastic	neoplastic	JJ
cord-022561-rv5j1201	1316	9	cells	cell	NNS
cord-022561-rv5j1201	1316	10	in	in	IN
cord-022561-rv5j1201	1316	11	the	the	DT
cord-022561-rv5j1201	1316	12	connective	connective	JJ
cord-022561-rv5j1201	1316	13	tissue	tissue	NN
cord-022561-rv5j1201	1316	14	around	around	IN
cord-022561-rv5j1201	1316	15	the	the	DT
cord-022561-rv5j1201	1316	16	portal	portal	JJ
cord-022561-rv5j1201	1316	17	triad	triad	NN
cord-022561-rv5j1201	1316	18	.	.	.
cord-022561-rv5j1201	1317	1	Plasma	plasma	NN
cord-022561-rv5j1201	1317	2	Cell	cell	NN
cord-022561-rv5j1201	1317	3	Neoplasia	Neoplasia	NNP
cord-022561-rv5j1201	1317	4	.	.	.
cord-022561-rv5j1201	1318	1	Plasma	plasma	NN
cord-022561-rv5j1201	1318	2	cell	cell	NN
cord-022561-rv5j1201	1318	3	neoplasms	neoplasm	NNS
cord-022561-rv5j1201	1318	4	are	be	VBP
cord-022561-rv5j1201	1318	5	most	most	RBS
cord-022561-rv5j1201	1318	6	easily	easily	RB
cord-022561-rv5j1201	1318	7	categorized	categorize	VBN
cord-022561-rv5j1201	1318	8	as	as	IN
cord-022561-rv5j1201	1318	9	myeloma	myeloma	NN
cord-022561-rv5j1201	1318	10	or	or	CC
cord-022561-rv5j1201	1318	11	multiple	multiple	JJ
cord-022561-rv5j1201	1318	12	myeloma	myeloma	NN
cord-022561-rv5j1201	1318	13	,	,	,
cord-022561-rv5j1201	1318	14	which	which	WDT
cord-022561-rv5j1201	1318	15	arises	arise	VBZ
cord-022561-rv5j1201	1318	16	in	in	IN
cord-022561-rv5j1201	1318	17	the	the	DT
cord-022561-rv5j1201	1318	18	bone	bone	NN
cord-022561-rv5j1201	1318	19	marrow	marrow	NN
cord-022561-rv5j1201	1318	20	,	,	,
cord-022561-rv5j1201	1318	21	and	and	CC
cord-022561-rv5j1201	1318	22	extramedullary	extramedullary	NNP
cord-022561-rv5j1201	1318	23	plasmacytoma	plasmacytoma	NNP
cord-022561-rv5j1201	1318	24	,	,	,
cord-022561-rv5j1201	1318	25	which	which	WDT
cord-022561-rv5j1201	1318	26	as	as	IN
cord-022561-rv5j1201	1318	27	the	the	DT
cord-022561-rv5j1201	1318	28	name	name	NN
cord-022561-rv5j1201	1318	29	implies	imply	VBZ
cord-022561-rv5j1201	1318	30	involves	involve	VBZ
cord-022561-rv5j1201	1318	31	sites	site	NNS
cord-022561-rv5j1201	1318	32	other	other	JJ
cord-022561-rv5j1201	1318	33	than	than	IN
cord-022561-rv5j1201	1318	34	bone	bone	NN
cord-022561-rv5j1201	1318	35	;	;	:
cord-022561-rv5j1201	1318	36	the	the	DT
cord-022561-rv5j1201	1318	37	latter	latter	JJ
cord-022561-rv5j1201	1318	38	is	be	VBZ
cord-022561-rv5j1201	1318	39	discussed	discuss	VBN
cord-022561-rv5j1201	1318	40	in	in	IN
cord-022561-rv5j1201	1318	41	the	the	DT
cord-022561-rv5j1201	1318	42	section	section	NN
cord-022561-rv5j1201	1318	43	on	on	IN
cord-022561-rv5j1201	1318	44	Lymphoid	Lymphoid	NNP
cord-022561-rv5j1201	1318	45	/	/	SYM
cord-022561-rv5j1201	1318	46	Lymphatic	Lymphatic	NNP
cord-022561-rv5j1201	1318	47	System	System	NNP
cord-022561-rv5j1201	1318	48	,	,	,
cord-022561-rv5j1201	1318	49	Disorders	disorder	NNS
cord-022561-rv5j1201	1318	50	of	of	IN
cord-022561-rv5j1201	1318	51	Domestic	domestic	JJ
cord-022561-rv5j1201	1318	52	Animals	animal	NNS
cord-022561-rv5j1201	1318	53	:	:	:
cord-022561-rv5j1201	1318	54	Lymph	lymph	NN
cord-022561-rv5j1201	1318	55	Nodes	node	NNS
cord-022561-rv5j1201	1318	56	,	,	,
cord-022561-rv5j1201	1318	57	Neoplasia	Neoplasia	NNP
cord-022561-rv5j1201	1318	58	,	,	,
cord-022561-rv5j1201	1318	59	Plasma	plasma	NN
cord-022561-rv5j1201	1318	60	Cell	Cell	NNP
cord-022561-rv5j1201	1318	61	Neoplasia	Neoplasia	NNP
cord-022561-rv5j1201	1318	62	.	.	.
cord-022561-rv5j1201	1319	1	Multiple	multiple	JJ
cord-022561-rv5j1201	1319	2	Myeloma	Myeloma	NNP
cord-022561-rv5j1201	1319	3	.	.	.
cord-022561-rv5j1201	1320	1	Multiple	multiple	JJ
cord-022561-rv5j1201	1320	2	myeloma	myeloma	NN
cord-022561-rv5j1201	1320	3	(	(	-LRB-
cord-022561-rv5j1201	1320	4	MM	MM	NNP
cord-022561-rv5j1201	1320	5	)	)	-RRB-
cord-022561-rv5j1201	1320	6	is	be	VBZ
cord-022561-rv5j1201	1320	7	a	a	DT
cord-022561-rv5j1201	1320	8	rare	rare	JJ
cord-022561-rv5j1201	1320	9	,	,	,
cord-022561-rv5j1201	1320	10	malignant	malignant	JJ
cord-022561-rv5j1201	1320	11	tumor	tumor	NN
cord-022561-rv5j1201	1320	12	of	of	IN
cord-022561-rv5j1201	1320	13	plasma	plasma	NN
cord-022561-rv5j1201	1320	14	cells	cell	NNS
cord-022561-rv5j1201	1320	15	that	that	WDT
cord-022561-rv5j1201	1320	16	arises	arise	VBZ
cord-022561-rv5j1201	1320	17	in	in	IN
cord-022561-rv5j1201	1320	18	the	the	DT
cord-022561-rv5j1201	1320	19	bone	bone	NN
cord-022561-rv5j1201	1320	20	marrow	marrow	NN
cord-022561-rv5j1201	1320	21	and	and	CC
cord-022561-rv5j1201	1320	22	usually	usually	RB
cord-022561-rv5j1201	1320	23	secretes	secrete	VBZ
cord-022561-rv5j1201	1320	24	large	large	JJ
cord-022561-rv5j1201	1320	25	amounts	amount	NNS
cord-022561-rv5j1201	1320	26	of	of	IN
cord-022561-rv5j1201	1320	27	immunoglobulin	immunoglobulin	NN
cord-022561-rv5j1201	1320	28	.	.	.
cord-022561-rv5j1201	1321	1	The	the	DT
cord-022561-rv5j1201	1321	2	finding	finding	NN
cord-022561-rv5j1201	1321	3	of	of	IN
cord-022561-rv5j1201	1321	4	neoplastic	neoplastic	JJ
cord-022561-rv5j1201	1321	5	plasma	plasma	NN
cord-022561-rv5j1201	1321	6	cells	cell	NNS
cord-022561-rv5j1201	1321	7	in	in	IN
cord-022561-rv5j1201	1321	8	blood	blood	NN
cord-022561-rv5j1201	1321	9	samples	sample	NNS
cord-022561-rv5j1201	1321	10	or	or	CC
cord-022561-rv5j1201	1321	11	smears	smear	NNS
cord-022561-rv5j1201	1321	12	is	be	VBZ
cord-022561-rv5j1201	1321	13	rare	rare	JJ
cord-022561-rv5j1201	1321	14	.	.	.
cord-022561-rv5j1201	1322	1	Dogs	dog	NNS
cord-022561-rv5j1201	1322	2	are	be	VBP
cord-022561-rv5j1201	1322	3	affected	affect	VBN
cord-022561-rv5j1201	1322	4	more	more	RBR
cord-022561-rv5j1201	1322	5	frequently	frequently	RB
cord-022561-rv5j1201	1322	6	than	than	IN
cord-022561-rv5j1201	1322	7	other	other	JJ
cord-022561-rv5j1201	1322	8	species	specie	NNS
cord-022561-rv5j1201	1322	9	,	,	,
cord-022561-rv5j1201	1322	10	but	but	CC
cord-022561-rv5j1201	1322	11	multiple	multiple	JJ
cord-022561-rv5j1201	1322	12	myeloma	myeloma	NN
cord-022561-rv5j1201	1322	13	has	have	VBZ
cord-022561-rv5j1201	1322	14	also	also	RB
cord-022561-rv5j1201	1322	15	been	be	VBN
cord-022561-rv5j1201	1322	16	reported	report	VBN
cord-022561-rv5j1201	1322	17	in	in	IN
cord-022561-rv5j1201	1322	18	horses	horse	NNS
cord-022561-rv5j1201	1322	19	,	,	,
cord-022561-rv5j1201	1322	20	cattle	cattle	NNS
cord-022561-rv5j1201	1322	21	,	,	,
cord-022561-rv5j1201	1322	22	cats	cat	NNS
cord-022561-rv5j1201	1322	23	,	,	,
cord-022561-rv5j1201	1322	24	and	and	CC
cord-022561-rv5j1201	1322	25	pigs	pig	NNS
cord-022561-rv5j1201	1322	26	.	.	.
cord-022561-rv5j1201	1323	1	Diagnosis	diagnosis	NN
cord-022561-rv5j1201	1323	2	of	of	IN
cord-022561-rv5j1201	1323	3	multiple	multiple	JJ
cord-022561-rv5j1201	1323	4	myeloma	myeloma	NN
cord-022561-rv5j1201	1323	5	is	be	VBZ
cord-022561-rv5j1201	1323	6	based	base	VBN
cord-022561-rv5j1201	1323	7	on	on	IN
cord-022561-rv5j1201	1323	8	finding	find	VBG
cord-022561-rv5j1201	1323	9	a	a	DT
cord-022561-rv5j1201	1323	10	minimum	minimum	NN
cord-022561-rv5j1201	1323	11	of	of	IN
cord-022561-rv5j1201	1323	12	two	two	CD
cord-022561-rv5j1201	1323	13	or	or	CC
cord-022561-rv5j1201	1323	14	three	three	CD
cord-022561-rv5j1201	1323	15	(	(	-LRB-
cord-022561-rv5j1201	1323	16	opinions	opinion	NNS
cord-022561-rv5j1201	1323	17	vary	vary	VBP
cord-022561-rv5j1201	1323	18	)	)	-RRB-
cord-022561-rv5j1201	1323	19	of	of	IN
cord-022561-rv5j1201	1323	20	the	the	DT
cord-022561-rv5j1201	1323	21	following	follow	VBG
cord-022561-rv5j1201	1323	22	abnormalities	abnormality	NNS
cord-022561-rv5j1201	1323	23	:	:	:
cord-022561-rv5j1201	1323	24	•	•	NNP
cord-022561-rv5j1201	1323	25	Markedly	markedly	RB
cord-022561-rv5j1201	1323	26	increased	increase	VBN
cord-022561-rv5j1201	1323	27	numbers	number	NNS
cord-022561-rv5j1201	1323	28	of	of	IN
cord-022561-rv5j1201	1323	29	plasma	plasma	NN
cord-022561-rv5j1201	1323	30	cells	cell	NNS
cord-022561-rv5j1201	1323	31	in	in	IN
cord-022561-rv5j1201	1323	32	the	the	DT
cord-022561-rv5j1201	1323	33	bone	bone	NN
cord-022561-rv5j1201	1323	34	marrow	marrow	NN
cord-022561-rv5j1201	1323	35	(	(	-LRB-
cord-022561-rv5j1201	1323	36	Fig	Fig	NNP
cord-022561-rv5j1201	1323	37	.	.	.
cord-022561-rv5j1201	1323	38	13	13	CD
cord-022561-rv5j1201	1323	39	-	-	SYM
cord-022561-rv5j1201	1323	40	32	32	CD
cord-022561-rv5j1201	1323	41	,	,	,
cord-022561-rv5j1201	1323	42	A	a	NN
cord-022561-rv5j1201	1323	43	)	)	-RRB-
cord-022561-rv5j1201	1324	1	•	•	NNP
cord-022561-rv5j1201	1325	1	Monoclonal	Monoclonal	NNP
cord-022561-rv5j1201	1325	2	gammopathy	gammopathy	NNP
cord-022561-rv5j1201	1326	1	•	•	NNP
cord-022561-rv5j1201	1327	1	Radiographic	radiographic	JJ
cord-022561-rv5j1201	1327	2	evidence	evidence	NN
cord-022561-rv5j1201	1327	3	of	of	IN
cord-022561-rv5j1201	1327	4	osteolysis	osteolysis	NN
cord-022561-rv5j1201	1328	1	•	•	NNP
cord-022561-rv5j1201	1329	1	Light	light	JJ
cord-022561-rv5j1201	1329	2	chain	chain	NN
cord-022561-rv5j1201	1329	3	proteinuria	proteinuria	NN
cord-022561-rv5j1201	1329	4	The	the	DT
cord-022561-rv5j1201	1329	5	classic	classic	JJ
cord-022561-rv5j1201	1329	6	laboratory	laboratory	NN
cord-022561-rv5j1201	1329	7	finding	finding	NN
cord-022561-rv5j1201	1329	8	in	in	IN
cord-022561-rv5j1201	1329	9	patients	patient	NNS
cord-022561-rv5j1201	1329	10	with	with	IN
cord-022561-rv5j1201	1329	11	multiple	multiple	JJ
cord-022561-rv5j1201	1329	12	myeloma	myeloma	NN
cord-022561-rv5j1201	1329	13	is	be	VBZ
cord-022561-rv5j1201	1329	14	hyperglobulinemia	hyperglobulinemia	NN
cord-022561-rv5j1201	1329	15	,	,	,
cord-022561-rv5j1201	1329	16	which	which	WDT
cord-022561-rv5j1201	1329	17	results	result	VBZ
cord-022561-rv5j1201	1329	18	from	from	IN
cord-022561-rv5j1201	1329	19	the	the	DT
cord-022561-rv5j1201	1329	20	excessive	excessive	JJ
cord-022561-rv5j1201	1329	21	production	production	NN
cord-022561-rv5j1201	1329	22	of	of	IN
cord-022561-rv5j1201	1329	23	immunoglobulin	immunoglobulin	NN
cord-022561-rv5j1201	1329	24	or	or	CC
cord-022561-rv5j1201	1329	25	an	an	DT
cord-022561-rv5j1201	1329	26	immunoglobulin	immunoglobulin	NN
cord-022561-rv5j1201	1329	27	subunit	subunit	NN
cord-022561-rv5j1201	1329	28	by	by	IN
cord-022561-rv5j1201	1329	29	the	the	DT
cord-022561-rv5j1201	1329	30	neoplastic	neoplastic	JJ
cord-022561-rv5j1201	1329	31	cells	cell	NNS
cord-022561-rv5j1201	1329	32	.	.	.
cord-022561-rv5j1201	1330	1	This	this	DT
cord-022561-rv5j1201	1330	2	homogeneous	homogeneous	JJ
cord-022561-rv5j1201	1330	3	protein	protein	NN
cord-022561-rv5j1201	1330	4	fraction	fraction	NN
cord-022561-rv5j1201	1330	5	is	be	VBZ
cord-022561-rv5j1201	1330	6	often	often	RB
cord-022561-rv5j1201	1330	7	called	call	VBN
cord-022561-rv5j1201	1330	8	paraprotein	paraprotein	NNP
cord-022561-rv5j1201	1330	9	or	or	CC
cord-022561-rv5j1201	1330	10	M	M	NNP
cord-022561-rv5j1201	1330	11	protein	protein	NN
cord-022561-rv5j1201	1330	12	.	.	.
cord-022561-rv5j1201	1331	1	Paraproteins	paraprotein	NNS
cord-022561-rv5j1201	1331	2	produced	produce	VBD
cord-022561-rv5j1201	1331	3	from	from	IN
cord-022561-rv5j1201	1331	4	the	the	DT
cord-022561-rv5j1201	1331	5	same	same	JJ
cord-022561-rv5j1201	1331	6	clone	clone	NN
cord-022561-rv5j1201	1331	7	of	of	IN
cord-022561-rv5j1201	1331	8	plasma	plasma	NN
cord-022561-rv5j1201	1331	9	cells	cell	NNS
cord-022561-rv5j1201	1331	10	have	have	VBP
cord-022561-rv5j1201	1331	11	the	the	DT
cord-022561-rv5j1201	1331	12	same	same	JJ
cord-022561-rv5j1201	1331	13	molecular	molecular	JJ
cord-022561-rv5j1201	1331	14	weight	weight	NN
cord-022561-rv5j1201	1331	15	and	and	CC
cord-022561-rv5j1201	1331	16	electric	electric	JJ
cord-022561-rv5j1201	1331	17	charge	charge	NN
cord-022561-rv5j1201	1331	18	.	.	.
cord-022561-rv5j1201	1332	1	Therefore	therefore	RB
cord-022561-rv5j1201	1332	2	they	-PRON-	PRP
cord-022561-rv5j1201	1332	3	have	have	VBP
cord-022561-rv5j1201	1332	4	the	the	DT
cord-022561-rv5j1201	1332	5	same	same	JJ
cord-022561-rv5j1201	1332	6	migration	migration	NN
cord-022561-rv5j1201	1332	7	pattern	pattern	NN
cord-022561-rv5j1201	1332	8	using	use	VBG
cord-022561-rv5j1201	1332	9	serum	serum	NN
cord-022561-rv5j1201	1332	10	protein	protein	NN
cord-022561-rv5j1201	1332	11	electrophoresis	electrophoresis	NN
cord-022561-rv5j1201	1332	12	,	,	,
cord-022561-rv5j1201	1332	13	which	which	WDT
cord-022561-rv5j1201	1332	14	results	result	VBZ
cord-022561-rv5j1201	1332	15	in	in	IN
cord-022561-rv5j1201	1332	16	a	a	DT
cord-022561-rv5j1201	1332	17	tall	tall	JJ
cord-022561-rv5j1201	1332	18	,	,	,
cord-022561-rv5j1201	1332	19	narrow	narrow	JJ
cord-022561-rv5j1201	1332	20	spike	spike	NN
cord-022561-rv5j1201	1332	21	in	in	IN
cord-022561-rv5j1201	1332	22	the	the	DT
cord-022561-rv5j1201	1332	23	globulins	globulins	NNP
cord-022561-rv5j1201	1332	24	region	region	NN
cord-022561-rv5j1201	1332	25	,	,	,
cord-022561-rv5j1201	1332	26	termed	term	VBD
cord-022561-rv5j1201	1332	27	monoclonal	monoclonal	JJ
cord-022561-rv5j1201	1332	28	gammopathy	gammopathy	NN
cord-022561-rv5j1201	1332	29	(	(	-LRB-
cord-022561-rv5j1201	1332	30	see	see	VB
cord-022561-rv5j1201	1332	31	Fig	Fig	NNP
cord-022561-rv5j1201	1332	32	.	.	.
cord-022561-rv5j1201	1333	1	13	13	CD
cord-022561-rv5j1201	1333	2	-	-	SYM
cord-022561-rv5j1201	1333	3	32	32	CD
cord-022561-rv5j1201	1333	4	,	,	,
cord-022561-rv5j1201	1333	5	B	b	NN
cord-022561-rv5j1201	1333	6	)	)	-RRB-
cord-022561-rv5j1201	1333	7	.	.	.
cord-022561-rv5j1201	1334	1	The	the	DT
cord-022561-rv5j1201	1334	2	term	term	NN
cord-022561-rv5j1201	1334	3	gammopathy	gammopathy	NNP
cord-022561-rv5j1201	1334	4	is	be	VBZ
cord-022561-rv5j1201	1334	5	used	use	VBN
cord-022561-rv5j1201	1334	6	because	because	IN
cord-022561-rv5j1201	1334	7	most	most	JJS
cord-022561-rv5j1201	1334	8	immunoglobulins	immunoglobulin	NNS
cord-022561-rv5j1201	1334	9	migrate	migrate	VBP
cord-022561-rv5j1201	1334	10	in	in	IN
cord-022561-rv5j1201	1334	11	the	the	DT
cord-022561-rv5j1201	1334	12	γ	γ	NN
cord-022561-rv5j1201	1334	13	-	-	HYPH
cord-022561-rv5j1201	1334	14	region	region	NN
cord-022561-rv5j1201	1334	15	of	of	IN
cord-022561-rv5j1201	1334	16	an	an	DT
cord-022561-rv5j1201	1334	17	electrophoresis	electrophoresis	NN
cord-022561-rv5j1201	1334	18	gel	gel	NN
cord-022561-rv5j1201	1334	19	.	.	.
cord-022561-rv5j1201	1335	1	However	however	RB
cord-022561-rv5j1201	1335	2	,	,	,
cord-022561-rv5j1201	1335	3	some	some	DT
cord-022561-rv5j1201	1335	4	immunoglobulins	immunoglobulin	NNS
cord-022561-rv5j1201	1335	5	,	,	,
cord-022561-rv5j1201	1335	6	especially	especially	RB
cord-022561-rv5j1201	1335	7	immunoglobulin	immunoglobulin	NN
cord-022561-rv5j1201	1335	8	A	a	NN
cord-022561-rv5j1201	1335	9	(	(	-LRB-
cord-022561-rv5j1201	1335	10	IgA	IgA	NNP
cord-022561-rv5j1201	1335	11	)	)	-RRB-
cord-022561-rv5j1201	1335	12	and	and	CC
cord-022561-rv5j1201	1335	13	IgM	IgM	NNP
cord-022561-rv5j1201	1335	14	,	,	,
cord-022561-rv5j1201	1335	15	migrate	migrate	VB
cord-022561-rv5j1201	1335	16	to	to	IN
cord-022561-rv5j1201	1335	17	the	the	DT
cord-022561-rv5j1201	1335	18	β	β	NN
cord-022561-rv5j1201	1335	19	-	-	HYPH
cord-022561-rv5j1201	1335	20	region	region	NN
cord-022561-rv5j1201	1335	21	.	.	.
cord-022561-rv5j1201	1336	1	Occasionally	occasionally	RB
cord-022561-rv5j1201	1336	2	,	,	,
cord-022561-rv5j1201	1336	3	biclonal	biclonal	JJ
cord-022561-rv5j1201	1336	4	or	or	CC
cord-022561-rv5j1201	1336	5	other	other	JJ
cord-022561-rv5j1201	1336	6	atypical	atypical	JJ
cord-022561-rv5j1201	1336	7	electrophoretic	electrophoretic	JJ
cord-022561-rv5j1201	1336	8	patterns	pattern	NNS
cord-022561-rv5j1201	1336	9	may	may	MD
cord-022561-rv5j1201	1336	10	be	be	VB
cord-022561-rv5j1201	1336	11	seen	see	VBN
cord-022561-rv5j1201	1336	12	with	with	IN
cord-022561-rv5j1201	1336	13	multiple	multiple	JJ
cord-022561-rv5j1201	1336	14	myeloma	myeloma	NN
cord-022561-rv5j1201	1336	15	as	as	IN
cord-022561-rv5j1201	1336	16	a	a	DT
cord-022561-rv5j1201	1336	17	result	result	NN
cord-022561-rv5j1201	1336	18	of	of	IN
cord-022561-rv5j1201	1336	19	protein	protein	NN
cord-022561-rv5j1201	1336	20	degradation	degradation	NN
cord-022561-rv5j1201	1336	21	,	,	,
cord-022561-rv5j1201	1336	22	protein	protein	NN
cord-022561-rv5j1201	1336	23	complex	complex	JJ
cord-022561-rv5j1201	1336	24	formation	formation	NN
cord-022561-rv5j1201	1336	25	,	,	,
cord-022561-rv5j1201	1336	26	binding	bind	VBG
cord-022561-rv5j1201	1336	27	to	to	IN
cord-022561-rv5j1201	1336	28	other	other	JJ
cord-022561-rv5j1201	1336	29	proteins	protein	NNS
cord-022561-rv5j1201	1336	30	,	,	,
cord-022561-rv5j1201	1336	31	or	or	CC
cord-022561-rv5j1201	1336	32	when	when	WRB
cord-022561-rv5j1201	1336	33	the	the	DT
cord-022561-rv5j1201	1336	34	tumor	tumor	NN
cord-022561-rv5j1201	1336	35	includes	include	VBZ
cord-022561-rv5j1201	1336	36	more	more	JJR
cord-022561-rv5j1201	1336	37	than	than	IN
cord-022561-rv5j1201	1336	38	one	one	CD
cord-022561-rv5j1201	1336	39	clonal	clonal	JJ
cord-022561-rv5j1201	1336	40	population	population	NN
cord-022561-rv5j1201	1336	41	.	.	.
cord-022561-rv5j1201	1337	1	It	-PRON-	PRP
cord-022561-rv5j1201	1337	2	is	be	VBZ
cord-022561-rv5j1201	1337	3	important	important	JJ
cord-022561-rv5j1201	1337	4	to	to	TO
cord-022561-rv5j1201	1337	5	note	note	VB
cord-022561-rv5j1201	1337	6	that	that	DT
cord-022561-rv5j1201	1337	7	monoclonal	monoclonal	JJ
cord-022561-rv5j1201	1337	8	gammopathy	gammopathy	NNP
cord-022561-rv5j1201	1337	9	is	be	VBZ
cord-022561-rv5j1201	1337	10	not	not	RB
cord-022561-rv5j1201	1337	11	specific	specific	JJ
cord-022561-rv5j1201	1337	12	to	to	IN
cord-022561-rv5j1201	1337	13	multiple	multiple	JJ
cord-022561-rv5j1201	1337	14	myeloma	myeloma	NN
cord-022561-rv5j1201	1337	15	but	but	CC
cord-022561-rv5j1201	1337	16	has	have	VBZ
cord-022561-rv5j1201	1337	17	also	also	RB
cord-022561-rv5j1201	1337	18	been	be	VBN
cord-022561-rv5j1201	1337	19	reported	report	VBN
cord-022561-rv5j1201	1337	20	with	with	IN
cord-022561-rv5j1201	1337	21	lymphoma	lymphoma	NN
cord-022561-rv5j1201	1337	22	,	,	,
cord-022561-rv5j1201	1337	23	chronic	chronic	JJ
cord-022561-rv5j1201	1337	24	lymphocytic	lymphocytic	JJ
cord-022561-rv5j1201	1337	25	leukemia	leukemia	NN
cord-022561-rv5j1201	1337	26	,	,	,
cord-022561-rv5j1201	1337	27	canine	canine	JJ
cord-022561-rv5j1201	1337	28	ehrlichiosis	ehrlichiosis	NN
cord-022561-rv5j1201	1337	29	,	,	,
cord-022561-rv5j1201	1337	30	and	and	CC
cord-022561-rv5j1201	1337	31	canine	canine	JJ
cord-022561-rv5j1201	1337	32	leishmaniasis	leishmaniasis	NN
cord-022561-rv5j1201	1337	33	.	.	.
cord-022561-rv5j1201	1338	1	Definitively	definitively	RB
cord-022561-rv5j1201	1338	2	distinguishing	distinguish	VBG
cord-022561-rv5j1201	1338	3	monoclonal	monoclonal	JJ
cord-022561-rv5j1201	1338	4	from	from	IN
cord-022561-rv5j1201	1338	5	polyclonal	polyclonal	JJ
cord-022561-rv5j1201	1338	6	gammopathy	gammopathy	NNP
cord-022561-rv5j1201	1338	7	requires	require	VBZ
cord-022561-rv5j1201	1338	8	immunoelectrophoresis	immunoelectrophoresis	NN
cord-022561-rv5j1201	1338	9	or	or	CC
cord-022561-rv5j1201	1338	10	immunofixation	immunofixation	NN
cord-022561-rv5j1201	1338	11	using	use	VBG
cord-022561-rv5j1201	1338	12	species	species	NN
cord-022561-rv5j1201	1338	13	-	-	HYPH
cord-022561-rv5j1201	1338	14	specific	specific	JJ
cord-022561-rv5j1201	1338	15	antibodies	antibody	NNS
cord-022561-rv5j1201	1338	16	recognizing	recognize	VBG
cord-022561-rv5j1201	1338	17	different	different	JJ
cord-022561-rv5j1201	1338	18	immunoglobulin	immunoglobulin	NN
cord-022561-rv5j1201	1338	19	subclasses	subclass	NNS
cord-022561-rv5j1201	1338	20	and	and	CC
cord-022561-rv5j1201	1338	21	subunits	subunit	NNS
cord-022561-rv5j1201	1338	22	.	.	.
cord-022561-rv5j1201	1339	1	Occasionally	occasionally	RB
cord-022561-rv5j1201	1339	2	,	,	,
cord-022561-rv5j1201	1339	3	multiple	multiple	JJ
cord-022561-rv5j1201	1339	4	myeloma	myeloma	NN
cord-022561-rv5j1201	1339	5	cells	cell	NNS
cord-022561-rv5j1201	1339	6	produce	produce	VBP
cord-022561-rv5j1201	1339	7	only	only	RB
cord-022561-rv5j1201	1339	8	the	the	DT
cord-022561-rv5j1201	1339	9	immunoglobulin	immunoglobulin	NN
cord-022561-rv5j1201	1339	10	light	light	NN
cord-022561-rv5j1201	1339	11	chain	chain	NN
cord-022561-rv5j1201	1339	12	.	.	.
cord-022561-rv5j1201	1340	1	An	an	DT
cord-022561-rv5j1201	1340	2	immunoglobulin	immunoglobulin	NN
cord-022561-rv5j1201	1340	3	monomer	monomer	NN
cord-022561-rv5j1201	1340	4	consists	consist	VBZ
cord-022561-rv5j1201	1340	5	of	of	IN
cord-022561-rv5j1201	1340	6	two	two	CD
cord-022561-rv5j1201	1340	7	heavy	heavy	JJ
cord-022561-rv5j1201	1340	8	chains	chain	NNS
cord-022561-rv5j1201	1340	9	and	and	CC
cord-022561-rv5j1201	1340	10	two	two	CD
cord-022561-rv5j1201	1340	11	light	light	JJ
cord-022561-rv5j1201	1340	12	chains	chain	NNS
cord-022561-rv5j1201	1340	13	connected	connect	VBN
cord-022561-rv5j1201	1340	14	by	by	IN
cord-022561-rv5j1201	1340	15	disulfide	disulfide	JJ
cord-022561-rv5j1201	1340	16	bonds	bond	NNS
cord-022561-rv5j1201	1340	17	.	.	.
cord-022561-rv5j1201	1341	1	These	these	DT
cord-022561-rv5j1201	1341	2	light	light	JJ
cord-022561-rv5j1201	1341	3	chains	chain	NNS
cord-022561-rv5j1201	1341	4	may	may	MD
cord-022561-rv5j1201	1341	5	deposit	deposit	VB
cord-022561-rv5j1201	1341	6	in	in	IN
cord-022561-rv5j1201	1341	7	tissues	tissue	NNS
cord-022561-rv5j1201	1341	8	and	and	CC
cord-022561-rv5j1201	1341	9	cause	cause	VB
cord-022561-rv5j1201	1341	10	organ	organ	NN
cord-022561-rv5j1201	1341	11	dysfunction	dysfunction	NN
cord-022561-rv5j1201	1341	12	,	,	,
cord-022561-rv5j1201	1341	13	especially	especially	RB
cord-022561-rv5j1201	1341	14	renal	renal	JJ
cord-022561-rv5j1201	1341	15	failure	failure	NN
cord-022561-rv5j1201	1341	16	.	.	.
cord-022561-rv5j1201	1342	1	When	when	WRB
cord-022561-rv5j1201	1342	2	the	the	DT
cord-022561-rv5j1201	1342	3	light	light	JJ
cord-022561-rv5j1201	1342	4	chains	chain	NNS
cord-022561-rv5j1201	1342	5	form	form	VBP
cord-022561-rv5j1201	1342	6	amyloid	amyloid	NN
cord-022561-rv5j1201	1342	7	deposits	deposit	NNS
cord-022561-rv5j1201	1342	8	,	,	,
cord-022561-rv5j1201	1342	9	the	the	DT
cord-022561-rv5j1201	1342	10	disease	disease	NN
cord-022561-rv5j1201	1342	11	is	be	VBZ
cord-022561-rv5j1201	1342	12	called	call	VBN
cord-022561-rv5j1201	1342	13	amyloid	amyloid	JJ
cord-022561-rv5j1201	1342	14	light	light	NN
cord-022561-rv5j1201	1342	15	chain	chain	NN
cord-022561-rv5j1201	1342	16	amyloidosis	amyloidosis	NN
cord-022561-rv5j1201	1342	17	.	.	.
cord-022561-rv5j1201	1343	1	But	but	CC
cord-022561-rv5j1201	1343	2	if	if	IN
cord-022561-rv5j1201	1343	3	marrow	marrow	NN
cord-022561-rv5j1201	1343	4	is	be	VBZ
cord-022561-rv5j1201	1343	5	dark	dark	JJ
cord-022561-rv5j1201	1343	6	red	red	JJ
cord-022561-rv5j1201	1343	7	as	as	IN
cord-022561-rv5j1201	1343	8	a	a	DT
cord-022561-rv5j1201	1343	9	result	result	NN
cord-022561-rv5j1201	1343	10	of	of	IN
cord-022561-rv5j1201	1343	11	replacement	replacement	NN
cord-022561-rv5j1201	1343	12	of	of	IN
cord-022561-rv5j1201	1343	13	fat	fat	NN
cord-022561-rv5j1201	1343	14	by	by	IN
cord-022561-rv5j1201	1343	15	hematopoietic	hematopoietic	JJ
cord-022561-rv5j1201	1343	16	tissue	tissue	NN
cord-022561-rv5j1201	1343	17	;	;	:
cord-022561-rv5j1201	1343	18	the	the	DT
cord-022561-rv5j1201	1343	19	extent	extent	NN
cord-022561-rv5j1201	1343	20	of	of	IN
cord-022561-rv5j1201	1343	21	replacement	replacement	NN
cord-022561-rv5j1201	1343	22	is	be	VBZ
cord-022561-rv5j1201	1343	23	an	an	DT
cord-022561-rv5j1201	1343	24	indication	indication	NN
cord-022561-rv5j1201	1343	25	of	of	IN
cord-022561-rv5j1201	1343	26	the	the	DT
cord-022561-rv5j1201	1343	27	duration	duration	NN
cord-022561-rv5j1201	1343	28	of	of	IN
cord-022561-rv5j1201	1343	29	the	the	DT
cord-022561-rv5j1201	1343	30	anemia	anemia	NN
cord-022561-rv5j1201	1343	31	.	.	.
cord-022561-rv5j1201	1344	1	The	the	DT
cord-022561-rv5j1201	1344	2	severity	severity	NN
cord-022561-rv5j1201	1344	3	of	of	IN
cord-022561-rv5j1201	1344	4	microscopic	microscopic	JJ
cord-022561-rv5j1201	1344	5	lesions	lesion	NNS
cord-022561-rv5j1201	1344	6	is	be	VBZ
cord-022561-rv5j1201	1344	7	dependent	dependent	JJ
cord-022561-rv5j1201	1344	8	on	on	IN
cord-022561-rv5j1201	1344	9	the	the	DT
cord-022561-rv5j1201	1344	10	chronicity	chronicity	NN
cord-022561-rv5j1201	1344	11	of	of	IN
cord-022561-rv5j1201	1344	12	the	the	DT
cord-022561-rv5j1201	1344	13	disease	disease	NN
cord-022561-rv5j1201	1344	14	,	,	,
cord-022561-rv5j1201	1344	15	and	and	CC
cord-022561-rv5j1201	1344	16	they	-PRON-	PRP
cord-022561-rv5j1201	1344	17	are	be	VBP
cord-022561-rv5j1201	1344	18	most	most	RBS
cord-022561-rv5j1201	1344	19	significant	significant	JJ
cord-022561-rv5j1201	1344	20	in	in	IN
cord-022561-rv5j1201	1344	21	the	the	DT
cord-022561-rv5j1201	1344	22	spleen	spleen	NN
cord-022561-rv5j1201	1344	23	,	,	,
cord-022561-rv5j1201	1344	24	liver	liver	NN
cord-022561-rv5j1201	1344	25	,	,	,
cord-022561-rv5j1201	1344	26	and	and	CC
cord-022561-rv5j1201	1344	27	bone	bone	NN
cord-022561-rv5j1201	1344	28	marrow	marrow	NN
cord-022561-rv5j1201	1344	29	.	.	.
cord-022561-rv5j1201	1345	1	As	as	IN
cord-022561-rv5j1201	1345	2	would	would	MD
cord-022561-rv5j1201	1345	3	be	be	VB
cord-022561-rv5j1201	1345	4	anticipated	anticipate	VBN
cord-022561-rv5j1201	1345	5	,	,	,
cord-022561-rv5j1201	1345	6	microscopic	microscopic	JJ
cord-022561-rv5j1201	1345	7	findings	finding	NNS
cord-022561-rv5j1201	1345	8	of	of	IN
cord-022561-rv5j1201	1345	9	the	the	DT
cord-022561-rv5j1201	1345	10	spleen	spleen	NNS
cord-022561-rv5j1201	1345	11	are	be	VBP
cord-022561-rv5j1201	1345	12	predominantly	predominantly	RB
cord-022561-rv5j1201	1345	13	influenced	influence	VBN
cord-022561-rv5j1201	1345	14	by	by	IN
cord-022561-rv5j1201	1345	15	the	the	DT
cord-022561-rv5j1201	1345	16	number	number	NN
cord-022561-rv5j1201	1345	17	and	and	CC
cord-022561-rv5j1201	1345	18	activity	activity	NN
cord-022561-rv5j1201	1345	19	of	of	IN
cord-022561-rv5j1201	1345	20	macrophages	macrophage	NNS
cord-022561-rv5j1201	1345	21	,	,	,
cord-022561-rv5j1201	1345	22	which	which	WDT
cord-022561-rv5j1201	1345	23	is	be	VBZ
cord-022561-rv5j1201	1345	24	a	a	DT
cord-022561-rv5j1201	1345	25	reflection	reflection	NN
cord-022561-rv5j1201	1345	26	of	of	IN
cord-022561-rv5j1201	1345	27	the	the	DT
cord-022561-rv5j1201	1345	28	duration	duration	NN
cord-022561-rv5j1201	1345	29	of	of	IN
cord-022561-rv5j1201	1345	30	the	the	DT
cord-022561-rv5j1201	1345	31	disease	disease	NN
cord-022561-rv5j1201	1345	32	and	and	CC
cord-022561-rv5j1201	1345	33	the	the	DT
cord-022561-rv5j1201	1345	34	frequency	frequency	NN
cord-022561-rv5j1201	1345	35	of	of	IN
cord-022561-rv5j1201	1345	36	hemolytic	hemolytic	JJ
cord-022561-rv5j1201	1345	37	episodes	episode	NNS
cord-022561-rv5j1201	1345	38	.	.	.
cord-022561-rv5j1201	1346	1	Hemosiderin	Hemosiderin	NNP
cord-022561-rv5j1201	1346	2	-	-	HYPH
cord-022561-rv5j1201	1346	3	laden	laden	JJ
cord-022561-rv5j1201	1346	4	macrophages	macrophage	NNS
cord-022561-rv5j1201	1346	5	persist	persist	VBP
cord-022561-rv5j1201	1346	6	for	for	IN
cord-022561-rv5j1201	1346	7	months	month	NNS
cord-022561-rv5j1201	1346	8	to	to	IN
cord-022561-rv5j1201	1346	9	years	year	NNS
cord-022561-rv5j1201	1346	10	;	;	:
cord-022561-rv5j1201	1346	11	therefore	therefore	RB
cord-022561-rv5j1201	1346	12	large	large	JJ
cord-022561-rv5j1201	1346	13	numbers	number	NNS
cord-022561-rv5j1201	1346	14	are	be	VBP
cord-022561-rv5j1201	1346	15	consistent	consistent	JJ
cord-022561-rv5j1201	1346	16	with	with	IN
cord-022561-rv5j1201	1346	17	chronicity	chronicity	NN
cord-022561-rv5j1201	1346	18	.	.	.
cord-022561-rv5j1201	1347	1	Kupffer	Kupffer	NNP
cord-022561-rv5j1201	1347	2	cell	cell	NN
cord-022561-rv5j1201	1347	3	hyperplasia	hyperplasia	NN
cord-022561-rv5j1201	1347	4	with	with	IN
cord-022561-rv5j1201	1347	5	hemosiderin	hemosiderin	NNP
cord-022561-rv5j1201	1347	6	stores	store	NNS
cord-022561-rv5j1201	1347	7	and	and	CC
cord-022561-rv5j1201	1347	8	periportal	periportal	NNP
cord-022561-rv5j1201	1347	9	infiltrates	infiltrate	VBZ
cord-022561-rv5j1201	1347	10	of	of	IN
cord-022561-rv5j1201	1347	11	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	1347	12	are	be	VBP
cord-022561-rv5j1201	1347	13	the	the	DT
cord-022561-rv5j1201	1347	14	most	most	RBS
cord-022561-rv5j1201	1347	15	significant	significant	JJ
cord-022561-rv5j1201	1347	16	changes	change	NNS
cord-022561-rv5j1201	1347	17	in	in	IN
cord-022561-rv5j1201	1347	18	the	the	DT
cord-022561-rv5j1201	1347	19	liver	liver	NN
cord-022561-rv5j1201	1347	20	.	.	.
cord-022561-rv5j1201	1348	1	Bone	bone	NN
cord-022561-rv5j1201	1348	2	marrow	marrow	NN
cord-022561-rv5j1201	1348	3	histologic	histologic	JJ
cord-022561-rv5j1201	1348	4	findings	finding	NNS
cord-022561-rv5j1201	1348	5	vary	vary	VBP
cord-022561-rv5j1201	1348	6	depending	depend	VBG
cord-022561-rv5j1201	1348	7	on	on	IN
cord-022561-rv5j1201	1348	8	the	the	DT
cord-022561-rv5j1201	1348	9	duration	duration	NN
cord-022561-rv5j1201	1348	10	of	of	IN
cord-022561-rv5j1201	1348	11	the	the	DT
cord-022561-rv5j1201	1348	12	disease	disease	NN
cord-022561-rv5j1201	1348	13	.	.	.
cord-022561-rv5j1201	1349	1	In	in	IN
cord-022561-rv5j1201	1349	2	most	most	JJS
cord-022561-rv5j1201	1349	3	animals	animal	NNS
cord-022561-rv5j1201	1349	4	the	the	DT
cord-022561-rv5j1201	1349	5	marrow	marrow	NN
cord-022561-rv5j1201	1349	6	is	be	VBZ
cord-022561-rv5j1201	1349	7	cellular	cellular	JJ
cord-022561-rv5j1201	1349	8	because	because	IN
cord-022561-rv5j1201	1349	9	of	of	IN
cord-022561-rv5j1201	1349	10	the	the	DT
cord-022561-rv5j1201	1349	11	replacement	replacement	NN
cord-022561-rv5j1201	1349	12	of	of	IN
cord-022561-rv5j1201	1349	13	fat	fat	NN
cord-022561-rv5j1201	1349	14	by	by	IN
cord-022561-rv5j1201	1349	15	intense	intense	JJ
cord-022561-rv5j1201	1349	16	,	,	,
cord-022561-rv5j1201	1349	17	orderly	orderly	JJ
cord-022561-rv5j1201	1349	18	erythropoiesis	erythropoiesis	NN
cord-022561-rv5j1201	1349	19	.	.	.
cord-022561-rv5j1201	1350	1	Granulocytes	granulocyte	NNS
cord-022561-rv5j1201	1350	2	are	be	VBP
cord-022561-rv5j1201	1350	3	relatively	relatively	RB
cord-022561-rv5j1201	1350	4	less	less	RBR
cord-022561-rv5j1201	1350	5	numerous	numerous	JJ
cord-022561-rv5j1201	1350	6	,	,	,
cord-022561-rv5j1201	1350	7	and	and	CC
cord-022561-rv5j1201	1350	8	plasma	plasma	NN
cord-022561-rv5j1201	1350	9	cells	cell	NNS
cord-022561-rv5j1201	1350	10	are	be	VBP
cord-022561-rv5j1201	1350	11	increased	increase	VBN
cord-022561-rv5j1201	1350	12	.	.	.
cord-022561-rv5j1201	1351	1	As	as	IN
cord-022561-rv5j1201	1351	2	in	in	IN
cord-022561-rv5j1201	1351	3	the	the	DT
cord-022561-rv5j1201	1351	4	spleen	spleen	NN
cord-022561-rv5j1201	1351	5	,	,	,
cord-022561-rv5j1201	1351	6	hemosiderin	hemosiderin	NN
cord-022561-rv5j1201	1351	7	-	-	HYPH
cord-022561-rv5j1201	1351	8	laden	laden	JJ
cord-022561-rv5j1201	1351	9	macrophages	macrophage	NNS
cord-022561-rv5j1201	1351	10	are	be	VBP
cord-022561-rv5j1201	1351	11	present	present	JJ
cord-022561-rv5j1201	1351	12	in	in	IN
cord-022561-rv5j1201	1351	13	large	large	JJ
cord-022561-rv5j1201	1351	14	numbers	number	NNS
cord-022561-rv5j1201	1351	15	in	in	IN
cord-022561-rv5j1201	1351	16	chronic	chronic	JJ
cord-022561-rv5j1201	1351	17	cases	case	NNS
cord-022561-rv5j1201	1351	18	.	.	.
cord-022561-rv5j1201	1352	1	Emaciated	emaciated	JJ
cord-022561-rv5j1201	1352	2	animals	animal	NNS
cord-022561-rv5j1201	1352	3	with	with	IN
cord-022561-rv5j1201	1352	4	chronic	chronic	JJ
cord-022561-rv5j1201	1352	5	disease	disease	NN
cord-022561-rv5j1201	1352	6	have	have	VBP
cord-022561-rv5j1201	1352	7	serous	serous	JJ
cord-022561-rv5j1201	1352	8	atrophy	atrophy	NN
cord-022561-rv5j1201	1352	9	of	of	IN
cord-022561-rv5j1201	1352	10	fat	fat	NN
cord-022561-rv5j1201	1352	11	(	(	-LRB-
cord-022561-rv5j1201	1352	12	see	see	VB
cord-022561-rv5j1201	1352	13	E-	E-	NNP
cord-022561-rv5j1201	1352	14	Fig	Fig	NNP
cord-022561-rv5j1201	1352	15	.	.	.
cord-022561-rv5j1201	1353	1	13	13	CD
cord-022561-rv5j1201	1353	2	-	-	SYM
cord-022561-rv5j1201	1353	3	1	1	CD
cord-022561-rv5j1201	1353	4	)	)	-RRB-
cord-022561-rv5j1201	1353	5	.	.	.
cord-022561-rv5j1201	1354	1	Clinical	clinical	JJ
cord-022561-rv5j1201	1354	2	findings	finding	NNS
cord-022561-rv5j1201	1354	3	with	with	IN
cord-022561-rv5j1201	1354	4	viremic	viremic	JJ
cord-022561-rv5j1201	1354	5	episodes	episode	NNS
cord-022561-rv5j1201	1354	6	include	include	VBP
cord-022561-rv5j1201	1354	7	fever	fever	NN
cord-022561-rv5j1201	1354	8	,	,	,
cord-022561-rv5j1201	1354	9	depression	depression	NN
cord-022561-rv5j1201	1354	10	,	,	,
cord-022561-rv5j1201	1354	11	icterus	icterus	NN
cord-022561-rv5j1201	1354	12	,	,	,
cord-022561-rv5j1201	1354	13	petechial	petechial	JJ
cord-022561-rv5j1201	1354	14	hemorrhages	hemorrhage	NNS
cord-022561-rv5j1201	1354	15	,	,	,
cord-022561-rv5j1201	1354	16	lymph	lymph	NN
cord-022561-rv5j1201	1354	17	node	node	NN
cord-022561-rv5j1201	1354	18	enlargement	enlargement	NN
cord-022561-rv5j1201	1354	19	,	,	,
cord-022561-rv5j1201	1354	20	and	and	CC
cord-022561-rv5j1201	1354	21	dependent	dependent	JJ
cord-022561-rv5j1201	1354	22	edema	edema	NN
cord-022561-rv5j1201	1354	23	.	.	.
cord-022561-rv5j1201	1355	1	Equine	equine	JJ
cord-022561-rv5j1201	1355	2	infectious	infectious	JJ
cord-022561-rv5j1201	1355	3	anemia	anemia	NN
cord-022561-rv5j1201	1355	4	infection	infection	NN
cord-022561-rv5j1201	1355	5	is	be	VBZ
cord-022561-rv5j1201	1355	6	diagnosed	diagnose	VBN
cord-022561-rv5j1201	1355	7	on	on	IN
cord-022561-rv5j1201	1355	8	the	the	DT
cord-022561-rv5j1201	1355	9	basis	basis	NN
cord-022561-rv5j1201	1355	10	of	of	IN
cord-022561-rv5j1201	1355	11	the	the	DT
cord-022561-rv5j1201	1355	12	Coggins	Coggins	NNPS
cord-022561-rv5j1201	1355	13	test	test	NN
cord-022561-rv5j1201	1355	14	,	,	,
cord-022561-rv5j1201	1355	15	an	an	DT
cord-022561-rv5j1201	1355	16	agarose	agarose	JJ
cord-022561-rv5j1201	1355	17	gel	gel	NN
cord-022561-rv5j1201	1355	18	immunodiffusion	immunodiffusion	NN
cord-022561-rv5j1201	1355	19	test	test	NN
cord-022561-rv5j1201	1355	20	for	for	IN
cord-022561-rv5j1201	1355	21	the	the	DT
cord-022561-rv5j1201	1355	22	presence	presence	NN
cord-022561-rv5j1201	1355	23	of	of	IN
cord-022561-rv5j1201	1355	24	the	the	DT
cord-022561-rv5j1201	1355	25	antibody	antibody	NN
cord-022561-rv5j1201	1355	26	against	against	IN
cord-022561-rv5j1201	1355	27	the	the	DT
cord-022561-rv5j1201	1355	28	virus	virus	NN
cord-022561-rv5j1201	1355	29	.	.	.
cord-022561-rv5j1201	1356	1	Congenital	Congenital	NNP
cord-022561-rv5j1201	1356	2	Dyserythropoiesis	Dyserythropoiesis	NNP
cord-022561-rv5j1201	1356	3	in	in	IN
cord-022561-rv5j1201	1356	4	Polled	poll	VBN
cord-022561-rv5j1201	1356	5	Herefords	Herefords	NNP
cord-022561-rv5j1201	1356	6	.	.	.
cord-022561-rv5j1201	1357	1	A	a	DT
cord-022561-rv5j1201	1357	2	syndrome	syndrome	NN
cord-022561-rv5j1201	1357	3	of	of	IN
cord-022561-rv5j1201	1357	4	congenital	congenital	JJ
cord-022561-rv5j1201	1357	5	dyserythropoiesis	dyserythropoiesis	NN
cord-022561-rv5j1201	1357	6	and	and	CC
cord-022561-rv5j1201	1357	7	alopecia	alopecia	NN
cord-022561-rv5j1201	1357	8	occurs	occur	VBZ
cord-022561-rv5j1201	1357	9	in	in	IN
cord-022561-rv5j1201	1357	10	polled	poll	VBN
cord-022561-rv5j1201	1357	11	Hereford	Hereford	NNP
cord-022561-rv5j1201	1357	12	calves	calf	NNS
cord-022561-rv5j1201	1357	13	.	.	.
cord-022561-rv5j1201	1358	1	The	the	DT
cord-022561-rv5j1201	1358	2	cause	cause	NN
cord-022561-rv5j1201	1358	3	and	and	CC
cord-022561-rv5j1201	1358	4	pathogenesis	pathogenesis	NN
cord-022561-rv5j1201	1358	5	of	of	IN
cord-022561-rv5j1201	1358	6	this	this	DT
cord-022561-rv5j1201	1358	7	often	often	RB
cord-022561-rv5j1201	1358	8	fatal	fatal	JJ
cord-022561-rv5j1201	1358	9	disease	disease	NN
cord-022561-rv5j1201	1358	10	are	be	VBP
cord-022561-rv5j1201	1358	11	unknown	unknown	JJ
cord-022561-rv5j1201	1358	12	.	.	.
cord-022561-rv5j1201	1359	1	Early	early	RB
cord-022561-rv5j1201	1359	2	in	in	IN
cord-022561-rv5j1201	1359	3	disease	disease	NN
cord-022561-rv5j1201	1359	4	there	there	EX
cord-022561-rv5j1201	1359	5	is	be	VBZ
cord-022561-rv5j1201	1359	6	hyperkeratosis	hyperkeratosis	NN
cord-022561-rv5j1201	1359	7	and	and	CC
cord-022561-rv5j1201	1359	8	alopecia	alopecia	NN
cord-022561-rv5j1201	1359	9	of	of	IN
cord-022561-rv5j1201	1359	10	the	the	DT
cord-022561-rv5j1201	1359	11	muzzle	muzzle	NN
cord-022561-rv5j1201	1359	12	and	and	CC
cord-022561-rv5j1201	1359	13	ears	ear	NNS
cord-022561-rv5j1201	1359	14	,	,	,
cord-022561-rv5j1201	1359	15	which	which	WDT
cord-022561-rv5j1201	1359	16	progresses	progress	VBZ
cord-022561-rv5j1201	1359	17	to	to	IN
cord-022561-rv5j1201	1359	18	generalized	generalized	JJ
cord-022561-rv5j1201	1359	19	alopecia	alopecia	NN
cord-022561-rv5j1201	1359	20	and	and	CC
cord-022561-rv5j1201	1359	21	hyperkeratotic	hyperkeratotic	JJ
cord-022561-rv5j1201	1359	22	dermatitis	dermatitis	NN
cord-022561-rv5j1201	1359	23	.	.	.
cord-022561-rv5j1201	1360	1	Histologically	histologically	RB
cord-022561-rv5j1201	1360	2	,	,	,
cord-022561-rv5j1201	1360	3	there	there	EX
cord-022561-rv5j1201	1360	4	is	be	VBZ
cord-022561-rv5j1201	1360	5	orthokeratotic	orthokeratotic	JJ
cord-022561-rv5j1201	1360	6	hyperkeratosis	hyperkeratosis	NN
cord-022561-rv5j1201	1360	7	with	with	IN
cord-022561-rv5j1201	1360	8	dyskeratosis	dyskeratosis	NNP
cord-022561-rv5j1201	1360	9	,	,	,
cord-022561-rv5j1201	1360	10	as	as	RB
cord-022561-rv5j1201	1360	11	well	well	RB
cord-022561-rv5j1201	1360	12	as	as	IN
cord-022561-rv5j1201	1360	13	erythroid	erythroid	JJ
cord-022561-rv5j1201	1360	14	hyperplasia	hyperplasia	NN
cord-022561-rv5j1201	1360	15	,	,	,
cord-022561-rv5j1201	1360	16	dysplasia	dysplasia	NN
cord-022561-rv5j1201	1360	17	,	,	,
cord-022561-rv5j1201	1360	18	and	and	CC
cord-022561-rv5j1201	1360	19	maturation	maturation	NN
cord-022561-rv5j1201	1360	20	arrest	arrest	NN
cord-022561-rv5j1201	1360	21	in	in	IN
cord-022561-rv5j1201	1360	22	the	the	DT
cord-022561-rv5j1201	1360	23	bone	bone	NN
cord-022561-rv5j1201	1360	24	marrow	marrow	NN
cord-022561-rv5j1201	1360	25	.	.	.
cord-022561-rv5j1201	1361	1	Ineffective	ineffective	JJ
cord-022561-rv5j1201	1361	2	erythropoiesis	erythropoiesis	NN
cord-022561-rv5j1201	1361	3	results	result	NNS
cord-022561-rv5j1201	1361	4	in	in	IN
cord-022561-rv5j1201	1361	5	nonregenerative	nonregenerative	NN
cord-022561-rv5j1201	1361	6	to	to	TO
cord-022561-rv5j1201	1361	7	poorly	poorly	RB
cord-022561-rv5j1201	1361	8	regenerative	regenerative	JJ
cord-022561-rv5j1201	1361	9	anemia	anemia	NN
cord-022561-rv5j1201	1361	10	.	.	.
cord-022561-rv5j1201	1362	1	Erythrocyte	Erythrocyte	NNP
cord-022561-rv5j1201	1362	2	band	band	NN
cord-022561-rv5j1201	1362	3	3	3	CD
cord-022561-rv5j1201	1362	4	is	be	VBZ
cord-022561-rv5j1201	1362	5	integral	integral	JJ
cord-022561-rv5j1201	1362	6	membrane	membrane	NN
cord-022561-rv5j1201	1362	7	protein	protein	NN
cord-022561-rv5j1201	1362	8	that	that	WDT
cord-022561-rv5j1201	1362	9	connects	connect	VBZ
cord-022561-rv5j1201	1362	10	to	to	IN
cord-022561-rv5j1201	1362	11	the	the	DT
cord-022561-rv5j1201	1362	12	cytoskeleton	cytoskeleton	NN
cord-022561-rv5j1201	1362	13	and	and	CC
cord-022561-rv5j1201	1362	14	aids	aid	NNS
cord-022561-rv5j1201	1362	15	in	in	IN
cord-022561-rv5j1201	1362	16	erythrocyte	erythrocyte	NN
cord-022561-rv5j1201	1362	17	stability	stability	NN
cord-022561-rv5j1201	1362	18	.	.	.
cord-022561-rv5j1201	1363	1	A	a	DT
cord-022561-rv5j1201	1363	2	hereditary	hereditary	JJ
cord-022561-rv5j1201	1363	3	deficiency	deficiency	NN
cord-022561-rv5j1201	1363	4	of	of	IN
cord-022561-rv5j1201	1363	5	this	this	DT
cord-022561-rv5j1201	1363	6	protein	protein	NN
cord-022561-rv5j1201	1363	7	has	have	VBZ
cord-022561-rv5j1201	1363	8	been	be	VBN
cord-022561-rv5j1201	1363	9	identified	identify	VBN
cord-022561-rv5j1201	1363	10	in	in	IN
cord-022561-rv5j1201	1363	11	Japanese	japanese	JJ
cord-022561-rv5j1201	1363	12	black	black	JJ
cord-022561-rv5j1201	1363	13	cattle	cattle	NNS
cord-022561-rv5j1201	1363	14	,	,	,
cord-022561-rv5j1201	1363	15	resulting	result	VBG
cord-022561-rv5j1201	1363	16	in	in	IN
cord-022561-rv5j1201	1363	17	increased	increase	VBN
cord-022561-rv5j1201	1363	18	erythrocyte	erythrocyte	NN
cord-022561-rv5j1201	1363	19	fragility	fragility	NN
cord-022561-rv5j1201	1363	20	,	,	,
cord-022561-rv5j1201	1363	21	spherocytosis	spherocytosis	NNP
cord-022561-rv5j1201	1363	22	,	,	,
cord-022561-rv5j1201	1363	23	intravascular	intravascular	JJ
cord-022561-rv5j1201	1363	24	hemolytic	hemolytic	JJ
cord-022561-rv5j1201	1363	25	anemia	anemia	NN
cord-022561-rv5j1201	1363	26	,	,	,
cord-022561-rv5j1201	1363	27	and	and	CC
cord-022561-rv5j1201	1363	28	retarded	retarded	JJ
cord-022561-rv5j1201	1363	29	growth	growth	NN
cord-022561-rv5j1201	1363	30	.	.	.
cord-022561-rv5j1201	1364	1	Affected	affected	JJ
cord-022561-rv5j1201	1364	2	calves	calf	NNS
cord-022561-rv5j1201	1364	3	show	show	VBP
cord-022561-rv5j1201	1364	4	lesions	lesion	NNS
cord-022561-rv5j1201	1364	5	consistent	consistent	JJ
cord-022561-rv5j1201	1364	6	with	with	IN
cord-022561-rv5j1201	1364	7	hemolytic	hemolytic	JJ
cord-022561-rv5j1201	1364	8	anemia	anemia	NN
cord-022561-rv5j1201	1364	9	,	,	,
cord-022561-rv5j1201	1364	10	including	include	VBG
cord-022561-rv5j1201	1364	11	pale	pale	JJ
cord-022561-rv5j1201	1364	12	mucous	mucous	JJ
cord-022561-rv5j1201	1364	13	membranes	membrane	NNS
cord-022561-rv5j1201	1364	14	,	,	,
cord-022561-rv5j1201	1364	15	icterus	icterus	NN
cord-022561-rv5j1201	1364	16	,	,	,
cord-022561-rv5j1201	1364	17	and	and	CC
cord-022561-rv5j1201	1364	18	splenomegaly	splenomegaly	NN
cord-022561-rv5j1201	1364	19	.	.	.
cord-022561-rv5j1201	1365	1	Histologically	histologically	RB
cord-022561-rv5j1201	1365	2	,	,	,
cord-022561-rv5j1201	1365	3	there	there	EX
cord-022561-rv5j1201	1365	4	are	be	VBP
cord-022561-rv5j1201	1365	5	bilirubin	bilirubin	JJ
cord-022561-rv5j1201	1365	6	accumulations	accumulation	NNS
cord-022561-rv5j1201	1365	7	in	in	IN
cord-022561-rv5j1201	1365	8	the	the	DT
cord-022561-rv5j1201	1365	9	liver	liver	NN
cord-022561-rv5j1201	1365	10	,	,	,
cord-022561-rv5j1201	1365	11	and	and	CC
cord-022561-rv5j1201	1365	12	hemosiderin	hemosiderin	NN
cord-022561-rv5j1201	1365	13	in	in	IN
cord-022561-rv5j1201	1365	14	renal	renal	JJ
cord-022561-rv5j1201	1365	15	tubules	tubule	NNS
cord-022561-rv5j1201	1365	16	.	.	.
cord-022561-rv5j1201	1366	1	Bovine	Bovine	NNP
cord-022561-rv5j1201	1366	2	Leukemia	Leukemia	NNP
cord-022561-rv5j1201	1366	3	Virus	Virus	NNP
cord-022561-rv5j1201	1366	4	.	.	.
cord-022561-rv5j1201	1367	1	Bovine	bovine	JJ
cord-022561-rv5j1201	1367	2	leukemia	leukemia	NN
cord-022561-rv5j1201	1367	3	virus	virus	NN
cord-022561-rv5j1201	1367	4	is	be	VBZ
cord-022561-rv5j1201	1367	5	discussed	discuss	VBN
cord-022561-rv5j1201	1367	6	in	in	IN
cord-022561-rv5j1201	1367	7	the	the	DT
cord-022561-rv5j1201	1367	8	later	later	JJ
cord-022561-rv5j1201	1367	9	section	section	NN
cord-022561-rv5j1201	1367	10	on	on	IN
cord-022561-rv5j1201	1367	11	lymphoma	lymphoma	NN
cord-022561-rv5j1201	1367	12	(	(	-LRB-
cord-022561-rv5j1201	1367	13	see	see	VB
cord-022561-rv5j1201	1367	14	Lymphoid	Lymphoid	NNP
cord-022561-rv5j1201	1367	15	/	/	SYM
cord-022561-rv5j1201	1367	16	Lymphatic	Lymphatic	NNP
cord-022561-rv5j1201	1367	17	System	System	NNP
cord-022561-rv5j1201	1367	18	,	,	,
cord-022561-rv5j1201	1367	19	Disorders	disorder	NNS
cord-022561-rv5j1201	1367	20	of	of	IN
cord-022561-rv5j1201	1367	21	Domestic	domestic	JJ
cord-022561-rv5j1201	1367	22	Animals	animal	NNS
cord-022561-rv5j1201	1367	23	:	:	:
cord-022561-rv5j1201	1367	24	Lymph	lymph	NN
cord-022561-rv5j1201	1367	25	Nodes	node	NNS
cord-022561-rv5j1201	1367	26	,	,	,
cord-022561-rv5j1201	1367	27	Neoplasia	neoplasia	NN
cord-022561-rv5j1201	1367	28	,	,	,
cord-022561-rv5j1201	1367	29	Lymphoma	Lymphoma	NNP
cord-022561-rv5j1201	1367	30	)	)	-RRB-
cord-022561-rv5j1201	1367	31	.	.	.
cord-022561-rv5j1201	1368	1	Bovine	bovine	JJ
cord-022561-rv5j1201	1368	2	Viral	Viral	NNP
cord-022561-rv5j1201	1368	3	Diarrhea	Diarrhea	NNP
cord-022561-rv5j1201	1368	4	Virus	Virus	NNP
cord-022561-rv5j1201	1368	5	.	.	.
cord-022561-rv5j1201	1369	1	BVDV	BVDV	NNP
cord-022561-rv5j1201	1369	2	infection	infection	NN
cord-022561-rv5j1201	1369	3	may	may	MD
cord-022561-rv5j1201	1369	4	cause	cause	VB
cord-022561-rv5j1201	1369	5	thrombocytopenia	thrombocytopenia	NN
cord-022561-rv5j1201	1369	6	in	in	IN
cord-022561-rv5j1201	1369	7	cattle	cattle	NNS
cord-022561-rv5j1201	1369	8	,	,	,
cord-022561-rv5j1201	1369	9	and	and	CC
cord-022561-rv5j1201	1369	10	a	a	DT
cord-022561-rv5j1201	1369	11	thrombocytopenic	thrombocytopenic	JJ
cord-022561-rv5j1201	1369	12	hemorrhagic	hemorrhagic	JJ
cord-022561-rv5j1201	1369	13	syndrome	syndrome	NN
cord-022561-rv5j1201	1369	14	has	have	VBZ
cord-022561-rv5j1201	1369	15	been	be	VBN
cord-022561-rv5j1201	1369	16	specifically	specifically	RB
cord-022561-rv5j1201	1369	17	caused	cause	VBN
cord-022561-rv5j1201	1369	18	by	by	IN
cord-022561-rv5j1201	1369	19	type	type	NN
cord-022561-rv5j1201	1369	20	II	II	NNP
cord-022561-rv5j1201	1369	21	BVDV	BVDV	NNP
cord-022561-rv5j1201	1369	22	infection	infection	NN
cord-022561-rv5j1201	1369	23	.	.	.
cord-022561-rv5j1201	1370	1	Investigations	investigation	NNS
cord-022561-rv5j1201	1370	2	of	of	IN
cord-022561-rv5j1201	1370	3	the	the	DT
cord-022561-rv5j1201	1370	4	mechanism	mechanism	NN
cord-022561-rv5j1201	1370	5	of	of	IN
cord-022561-rv5j1201	1370	6	BVDV	BVDV	NNP
cord-022561-rv5j1201	1370	7	-	-	HYPH
cord-022561-rv5j1201	1370	8	induced	induce	VBN
cord-022561-rv5j1201	1370	9	thrombocytopenia	thrombocytopenia	NNS
cord-022561-rv5j1201	1370	10	have	have	VBP
cord-022561-rv5j1201	1370	11	resulted	result	VBN
cord-022561-rv5j1201	1370	12	in	in	IN
cord-022561-rv5j1201	1370	13	varying	varying	NN
cord-022561-rv5j1201	1370	14	,	,	,
cord-022561-rv5j1201	1370	15	sometimes	sometimes	RB
cord-022561-rv5j1201	1370	16	conflicting	conflict	VBG
cord-022561-rv5j1201	1370	17	,	,	,
cord-022561-rv5j1201	1370	18	conclusions	conclusion	NNS
cord-022561-rv5j1201	1370	19	.	.	.
cord-022561-rv5j1201	1371	1	More	More	JJR
cord-022561-rv5j1201	1371	2	than	than	IN
cord-022561-rv5j1201	1371	3	one	one	CD
cord-022561-rv5j1201	1371	4	study	study	NN
cord-022561-rv5j1201	1371	5	has	have	VBZ
cord-022561-rv5j1201	1371	6	shown	show	VBN
cord-022561-rv5j1201	1371	7	viral	viral	JJ
cord-022561-rv5j1201	1371	8	antigen	antigen	NN
cord-022561-rv5j1201	1371	9	within	within	IN
cord-022561-rv5j1201	1371	10	bone	bone	NN
cord-022561-rv5j1201	1371	11	marrow	marrow	NN
cord-022561-rv5j1201	1371	12	megakaryocytes	megakaryocyte	NNS
cord-022561-rv5j1201	1371	13	and	and	CC
cord-022561-rv5j1201	1371	14	circulating	circulate	VBG
cord-022561-rv5j1201	1371	15	platelets	platelet	NNS
cord-022561-rv5j1201	1371	16	.	.	.
cord-022561-rv5j1201	1372	1	Evidence	evidence	NN
cord-022561-rv5j1201	1372	2	of	of	IN
cord-022561-rv5j1201	1372	3	impaired	impaired	JJ
cord-022561-rv5j1201	1372	4	thrombopoiesis	thrombopoiesis	NNP
cord-022561-rv5j1201	1372	5	(	(	-LRB-
cord-022561-rv5j1201	1372	6	megakaryocyte	megakaryocyte	NNP
cord-022561-rv5j1201	1372	7	necrosis	necrosis	NNP
cord-022561-rv5j1201	1372	8	,	,	,
cord-022561-rv5j1201	1372	9	megakaryocyte	megakaryocyte	NNP
cord-022561-rv5j1201	1372	10	pyknosis	pyknosis	NNP
cord-022561-rv5j1201	1372	11	,	,	,
cord-022561-rv5j1201	1372	12	osteoclasts	osteoclast	NNS
cord-022561-rv5j1201	1372	13	support	support	VBP
cord-022561-rv5j1201	1372	14	the	the	DT
cord-022561-rv5j1201	1372	15	growth	growth	NN
cord-022561-rv5j1201	1372	16	of	of	IN
cord-022561-rv5j1201	1372	17	myeloma	myeloma	NN
cord-022561-rv5j1201	1372	18	cells	cell	NNS
cord-022561-rv5j1201	1372	19	,	,	,
cord-022561-rv5j1201	1372	20	and	and	CC
cord-022561-rv5j1201	1372	21	that	that	IN
cord-022561-rv5j1201	1372	22	direct	direct	JJ
cord-022561-rv5j1201	1372	23	contact	contact	NN
cord-022561-rv5j1201	1372	24	between	between	IN
cord-022561-rv5j1201	1372	25	the	the	DT
cord-022561-rv5j1201	1372	26	two	two	CD
cord-022561-rv5j1201	1372	27	cell	cell	NN
cord-022561-rv5j1201	1372	28	types	type	NNS
cord-022561-rv5j1201	1372	29	increases	increase	VBZ
cord-022561-rv5j1201	1372	30	the	the	DT
cord-022561-rv5j1201	1372	31	myeloma	myeloma	NN
cord-022561-rv5j1201	1372	32	cell	cell	NN
cord-022561-rv5j1201	1372	33	proliferation	proliferation	NN
cord-022561-rv5j1201	1372	34	and	and	CC
cord-022561-rv5j1201	1372	35	promotes	promote	VBZ
cord-022561-rv5j1201	1372	36	osteoclast	osteoclast	JJ
cord-022561-rv5j1201	1372	37	survival	survival	NN
cord-022561-rv5j1201	1372	38	.	.	.
cord-022561-rv5j1201	1373	1	Increased	increase	VBN
cord-022561-rv5j1201	1373	2	osteoclast	osteoclast	NN
cord-022561-rv5j1201	1373	3	activity	activity	NN
cord-022561-rv5j1201	1373	4	causes	cause	VBZ
cord-022561-rv5j1201	1373	5	osteolysis	osteolysis	NN
cord-022561-rv5j1201	1373	6	,	,	,
cord-022561-rv5j1201	1373	7	but	but	CC
cord-022561-rv5j1201	1373	8	the	the	DT
cord-022561-rv5j1201	1373	9	exact	exact	JJ
cord-022561-rv5j1201	1373	10	mechanism	mechanism	NN
cord-022561-rv5j1201	1373	11	is	be	VBZ
cord-022561-rv5j1201	1373	12	not	not	RB
cord-022561-rv5j1201	1373	13	known	know	VBN
cord-022561-rv5j1201	1373	14	.	.	.
cord-022561-rv5j1201	1374	1	Osteolysis	Osteolysis	NNP
cord-022561-rv5j1201	1374	2	often	often	RB
cord-022561-rv5j1201	1374	3	results	result	VBZ
cord-022561-rv5j1201	1374	4	in	in	IN
cord-022561-rv5j1201	1374	5	bone	bone	NN
cord-022561-rv5j1201	1374	6	pain	pain	NN
cord-022561-rv5j1201	1374	7	,	,	,
cord-022561-rv5j1201	1374	8	lytic	lytic	JJ
cord-022561-rv5j1201	1374	9	bone	bone	NN
cord-022561-rv5j1201	1374	10	lesions	lesion	NNS
cord-022561-rv5j1201	1374	11	on	on	IN
cord-022561-rv5j1201	1374	12	radiographs	radiograph	NNS
cord-022561-rv5j1201	1374	13	,	,	,
cord-022561-rv5j1201	1374	14	hypercalcemia	hypercalcemia	NN
cord-022561-rv5j1201	1374	15	,	,	,
cord-022561-rv5j1201	1374	16	and	and	CC
cord-022561-rv5j1201	1374	17	increased	increase	VBD
cord-022561-rv5j1201	1374	18	serum	serum	JJ
cord-022561-rv5j1201	1374	19	alkaline	alkaline	JJ
cord-022561-rv5j1201	1374	20	phosphatase	phosphatase	NN
cord-022561-rv5j1201	1374	21	activity	activity	NN
cord-022561-rv5j1201	1374	22	.	.	.
cord-022561-rv5j1201	1375	1	Later	later	RB
cord-022561-rv5j1201	1375	2	in	in	IN
cord-022561-rv5j1201	1375	3	disease	disease	NN
cord-022561-rv5j1201	1375	4	,	,	,
cord-022561-rv5j1201	1375	5	osteolysis	osteolysis	NN
cord-022561-rv5j1201	1375	6	may	may	MD
cord-022561-rv5j1201	1375	7	cause	cause	VB
cord-022561-rv5j1201	1375	8	pathologic	pathologic	JJ
cord-022561-rv5j1201	1375	9	fractures	fracture	NNS
cord-022561-rv5j1201	1375	10	.	.	.
cord-022561-rv5j1201	1376	1	Morphologically	morphologically	RB
cord-022561-rv5j1201	1376	2	,	,	,
cord-022561-rv5j1201	1376	3	myeloma	myeloma	NN
cord-022561-rv5j1201	1376	4	cells	cell	NNS
cord-022561-rv5j1201	1376	5	tend	tend	VBP
cord-022561-rv5j1201	1376	6	to	to	TO
cord-022561-rv5j1201	1376	7	grow	grow	VB
cord-022561-rv5j1201	1376	8	in	in	IN
cord-022561-rv5j1201	1376	9	sheets	sheet	NNS
cord-022561-rv5j1201	1376	10	that	that	WDT
cord-022561-rv5j1201	1376	11	displace	displace	VBP
cord-022561-rv5j1201	1376	12	normal	normal	JJ
cord-022561-rv5j1201	1376	13	hematopoietic	hematopoietic	JJ
cord-022561-rv5j1201	1376	14	cells	cell	NNS
cord-022561-rv5j1201	1376	15	in	in	IN
cord-022561-rv5j1201	1376	16	the	the	DT
cord-022561-rv5j1201	1376	17	bone	bone	NN
cord-022561-rv5j1201	1376	18	marrow	marrow	NN
cord-022561-rv5j1201	1376	19	.	.	.
cord-022561-rv5j1201	1377	1	A	a	DT
cord-022561-rv5j1201	1377	2	proposed	propose	VBN
cord-022561-rv5j1201	1377	3	diagnostic	diagnostic	JJ
cord-022561-rv5j1201	1377	4	criterion	criterion	NN
cord-022561-rv5j1201	1377	5	of	of	IN
cord-022561-rv5j1201	1377	6	multiple	multiple	JJ
cord-022561-rv5j1201	1377	7	myeloma	myeloma	NN
cord-022561-rv5j1201	1377	8	is	be	VBZ
cord-022561-rv5j1201	1377	9	that	that	IN
cord-022561-rv5j1201	1377	10	plasma	plasma	NN
cord-022561-rv5j1201	1377	11	cells	cell	NNS
cord-022561-rv5j1201	1377	12	constitute	constitute	VBP
cord-022561-rv5j1201	1377	13	30	30	CD
cord-022561-rv5j1201	1377	14	%	%	NN
cord-022561-rv5j1201	1377	15	or	or	CC
cord-022561-rv5j1201	1377	16	more	more	JJR
cord-022561-rv5j1201	1377	17	of	of	IN
cord-022561-rv5j1201	1377	18	the	the	DT
cord-022561-rv5j1201	1377	19	nucleated	nucleated	JJ
cord-022561-rv5j1201	1377	20	cells	cell	NNS
cord-022561-rv5j1201	1377	21	in	in	IN
cord-022561-rv5j1201	1377	22	the	the	DT
cord-022561-rv5j1201	1377	23	marrow	marrow	NN
cord-022561-rv5j1201	1377	24	.	.	.
cord-022561-rv5j1201	1378	1	Welldifferentiated	welldifferentiated	JJ
cord-022561-rv5j1201	1378	2	plasma	plasma	NN
cord-022561-rv5j1201	1378	3	cells	cell	NNS
cord-022561-rv5j1201	1378	4	are	be	VBP
cord-022561-rv5j1201	1378	5	round	round	JJ
cord-022561-rv5j1201	1378	6	with	with	IN
cord-022561-rv5j1201	1378	7	abundant	abundant	JJ
cord-022561-rv5j1201	1378	8	basophilic	basophilic	NN
cord-022561-rv5j1201	1378	9	cytoplasm	cytoplasm	NN
cord-022561-rv5j1201	1378	10	(	(	-LRB-
cord-022561-rv5j1201	1378	11	due	due	JJ
cord-022561-rv5j1201	1378	12	to	to	IN
cord-022561-rv5j1201	1378	13	increased	increase	VBN
cord-022561-rv5j1201	1378	14	rough	rough	JJ
cord-022561-rv5j1201	1378	15	endoplasmic	endoplasmic	NN
cord-022561-rv5j1201	1378	16	reticulum	reticulum	NN
cord-022561-rv5j1201	1378	17	)	)	-RRB-
cord-022561-rv5j1201	1378	18	and	and	CC
cord-022561-rv5j1201	1378	19	a	a	DT
cord-022561-rv5j1201	1378	20	perinuclear	perinuclear	NNP
cord-022561-rv5j1201	1378	21	pale	pale	NNP
cord-022561-rv5j1201	1378	22	zone	zone	NN
cord-022561-rv5j1201	1378	23	(	(	-LRB-
cord-022561-rv5j1201	1378	24	enlarged	enlarge	VBN
cord-022561-rv5j1201	1378	25	Golgi	Golgi	NNP
cord-022561-rv5j1201	1378	26	apparatus	apparatus	NN
cord-022561-rv5j1201	1378	27	for	for	IN
cord-022561-rv5j1201	1378	28	the	the	DT
cord-022561-rv5j1201	1378	29	production	production	NN
cord-022561-rv5j1201	1378	30	of	of	IN
cord-022561-rv5j1201	1378	31	immunoglobulin	immunoglobulin	NN
cord-022561-rv5j1201	1378	32	)	)	-RRB-
cord-022561-rv5j1201	1378	33	;	;	:
cord-022561-rv5j1201	1378	34	anisocytosis	anisocytosis	NNP
cord-022561-rv5j1201	1378	35	and	and	CC
cord-022561-rv5j1201	1378	36	anisokaryosis	anisokaryosis	NNP
cord-022561-rv5j1201	1378	37	are	be	VBP
cord-022561-rv5j1201	1378	38	often	often	RB
cord-022561-rv5j1201	1378	39	mild	mild	JJ
cord-022561-rv5j1201	1378	40	but	but	CC
cord-022561-rv5j1201	1378	41	may	may	MD
cord-022561-rv5j1201	1378	42	be	be	VB
cord-022561-rv5j1201	1378	43	marked	mark	VBN
cord-022561-rv5j1201	1378	44	.	.	.
cord-022561-rv5j1201	1379	1	Some	some	DT
cord-022561-rv5j1201	1379	2	plasma	plasma	NN
cord-022561-rv5j1201	1379	3	cell	cell	NN
cord-022561-rv5j1201	1379	4	neoplasms	neoplasm	NNS
cord-022561-rv5j1201	1379	5	have	have	VBP
cord-022561-rv5j1201	1379	6	a	a	DT
cord-022561-rv5j1201	1379	7	bright	bright	JJ
cord-022561-rv5j1201	1379	8	eosinophilic	eosinophilic	JJ
cord-022561-rv5j1201	1379	9	fringe	fringe	NN
cord-022561-rv5j1201	1379	10	due	due	IN
cord-022561-rv5j1201	1379	11	to	to	IN
cord-022561-rv5j1201	1379	12	accumulated	accumulate	VBN
cord-022561-rv5j1201	1379	13	IgA	IgA	NNP
cord-022561-rv5j1201	1379	14	(	(	-LRB-
cord-022561-rv5j1201	1379	15	see	see	VB
cord-022561-rv5j1201	1379	16	Fig	Fig	NNP
cord-022561-rv5j1201	1379	17	.	.	.
cord-022561-rv5j1201	1380	1	13	13	CD
cord-022561-rv5j1201	1380	2	-	-	SYM
cord-022561-rv5j1201	1380	3	32	32	CD
cord-022561-rv5j1201	1380	4	,	,	,
cord-022561-rv5j1201	1380	5	A	A	NNP
cord-022561-rv5j1201	1380	6	)	)	-RRB-
cord-022561-rv5j1201	1380	7	.	.	.
cord-022561-rv5j1201	1381	1	Nuclei	nucleus	NNS
cord-022561-rv5j1201	1381	2	are	be	VBP
cord-022561-rv5j1201	1381	3	round	round	JJ
cord-022561-rv5j1201	1381	4	with	with	IN
cord-022561-rv5j1201	1381	5	clumped	clumped	JJ
cord-022561-rv5j1201	1381	6	chromatin	chromatin	NN
cord-022561-rv5j1201	1381	7	and	and	CC
cord-022561-rv5j1201	1381	8	often	often	RB
cord-022561-rv5j1201	1381	9	peripherally	peripherally	RB
cord-022561-rv5j1201	1381	10	placed	place	VBN
cord-022561-rv5j1201	1381	11	with	with	IN
cord-022561-rv5j1201	1381	12	the	the	DT
cord-022561-rv5j1201	1381	13	cytoplasm	cytoplasm	NN
cord-022561-rv5j1201	1381	14	;	;	:
cord-022561-rv5j1201	1381	15	binucleation	binucleation	NN
cord-022561-rv5j1201	1381	16	and	and	CC
cord-022561-rv5j1201	1381	17	multinucleation	multinucleation	NN
cord-022561-rv5j1201	1381	18	are	be	VBP
cord-022561-rv5j1201	1381	19	common	common	JJ
cord-022561-rv5j1201	1381	20	.	.	.
cord-022561-rv5j1201	1382	1	Poorly	poorly	RB
cord-022561-rv5j1201	1382	2	differentiated	differentiate	VBN
cord-022561-rv5j1201	1382	3	myeloma	myeloma	NN
cord-022561-rv5j1201	1382	4	cells	cell	NNS
cord-022561-rv5j1201	1382	5	may	may	MD
cord-022561-rv5j1201	1382	6	lack	lack	VB
cord-022561-rv5j1201	1382	7	and/or	and/or	CC
cord-022561-rv5j1201	1382	8	display	display	VB
cord-022561-rv5j1201	1382	9	less	less	RBR
cord-022561-rv5j1201	1382	10	characteristic	characteristic	JJ
cord-022561-rv5j1201	1382	11	features	feature	NNS
cord-022561-rv5j1201	1382	12	.	.	.
cord-022561-rv5j1201	1383	1	Osteolysis	osteolysis	NN
cord-022561-rv5j1201	1383	2	of	of	IN
cord-022561-rv5j1201	1383	3	bone	bone	NN
cord-022561-rv5j1201	1383	4	may	may	MD
cord-022561-rv5j1201	1383	5	be	be	VB
cord-022561-rv5j1201	1383	6	present	present	JJ
cord-022561-rv5j1201	1383	7	microscopically	microscopically	RB
cord-022561-rv5j1201	1383	8	.	.	.
cord-022561-rv5j1201	1384	1	Common	common	JJ
cord-022561-rv5j1201	1384	2	sites	site	NNS
cord-022561-rv5j1201	1384	3	of	of	IN
cord-022561-rv5j1201	1384	4	metastasis	metastasis	NN
cord-022561-rv5j1201	1384	5	include	include	VBP
cord-022561-rv5j1201	1384	6	the	the	DT
cord-022561-rv5j1201	1384	7	spleen	spleen	NN
cord-022561-rv5j1201	1384	8	,	,	,
cord-022561-rv5j1201	1384	9	liver	liver	NN
cord-022561-rv5j1201	1384	10	,	,	,
cord-022561-rv5j1201	1384	11	lymph	lymph	NN
cord-022561-rv5j1201	1384	12	nodes	node	NNS
cord-022561-rv5j1201	1384	13	,	,	,
cord-022561-rv5j1201	1384	14	and	and	CC
cord-022561-rv5j1201	1384	15	kidneys	kidney	NNS
cord-022561-rv5j1201	1384	16	.	.	.
cord-022561-rv5j1201	1385	1	Flavin	Flavin	NNP
cord-022561-rv5j1201	1385	2	Adenine	Adenine	NNP
cord-022561-rv5j1201	1385	3	Dinucleotide	Dinucleotide	NNP
cord-022561-rv5j1201	1385	4	Deficiency	Deficiency	NNP
cord-022561-rv5j1201	1385	5	.	.	.
cord-022561-rv5j1201	1386	1	Flavin	flavin	NN
cord-022561-rv5j1201	1386	2	adenine	adenine	NN
cord-022561-rv5j1201	1386	3	dinucleotide	dinucleotide	NN
cord-022561-rv5j1201	1386	4	(	(	-LRB-
cord-022561-rv5j1201	1386	5	FAD	fad	NN
cord-022561-rv5j1201	1386	6	)	)	-RRB-
cord-022561-rv5j1201	1386	7	is	be	VBZ
cord-022561-rv5j1201	1386	8	a	a	DT
cord-022561-rv5j1201	1386	9	cofactor	cofactor	NN
cord-022561-rv5j1201	1386	10	for	for	IN
cord-022561-rv5j1201	1386	11	cytochrome	cytochrome	NN
cord-022561-rv5j1201	1386	12	-	-	HYPH
cord-022561-rv5j1201	1386	13	b	b	NN
cord-022561-rv5j1201	1386	14	5	5	CD
cord-022561-rv5j1201	1386	15	reductase	reductase	NN
cord-022561-rv5j1201	1386	16	,	,	,
cord-022561-rv5j1201	1386	17	the	the	DT
cord-022561-rv5j1201	1386	18	enzyme	enzyme	NN
cord-022561-rv5j1201	1386	19	that	that	WDT
cord-022561-rv5j1201	1386	20	maintains	maintain	VBZ
cord-022561-rv5j1201	1386	21	hemoglobin	hemoglobin	NN
cord-022561-rv5j1201	1386	22	in	in	IN
cord-022561-rv5j1201	1386	23	its	-PRON-	PRP$
cord-022561-rv5j1201	1386	24	functional	functional	JJ
cord-022561-rv5j1201	1386	25	reduced	reduce	VBN
cord-022561-rv5j1201	1386	26	state	state	NN
cord-022561-rv5j1201	1386	27	,	,	,
cord-022561-rv5j1201	1386	28	and	and	CC
cord-022561-rv5j1201	1386	29	for	for	IN
cord-022561-rv5j1201	1386	30	glutathione	glutathione	NN
cord-022561-rv5j1201	1386	31	reductase	reductase	NN
cord-022561-rv5j1201	1386	32	,	,	,
cord-022561-rv5j1201	1386	33	an	an	DT
cord-022561-rv5j1201	1386	34	enzyme	enzyme	NN
cord-022561-rv5j1201	1386	35	that	that	WDT
cord-022561-rv5j1201	1386	36	also	also	RB
cord-022561-rv5j1201	1386	37	protects	protect	VBZ
cord-022561-rv5j1201	1386	38	erythrocytes	erythrocyte	NNS
cord-022561-rv5j1201	1386	39	from	from	IN
cord-022561-rv5j1201	1386	40	oxidative	oxidative	JJ
cord-022561-rv5j1201	1386	41	damage	damage	NN
cord-022561-rv5j1201	1386	42	.	.	.
cord-022561-rv5j1201	1387	1	Reported	report	VBN
cord-022561-rv5j1201	1387	2	in	in	IN
cord-022561-rv5j1201	1387	3	a	a	DT
cord-022561-rv5j1201	1387	4	Spanish	spanish	JJ
cord-022561-rv5j1201	1387	5	mustang	mustang	NNP
cord-022561-rv5j1201	1387	6	mare	mare	NN
cord-022561-rv5j1201	1387	7	and	and	CC
cord-022561-rv5j1201	1387	8	a	a	DT
cord-022561-rv5j1201	1387	9	Kentucky	Kentucky	NNP
cord-022561-rv5j1201	1387	10	mountain	mountain	NN
cord-022561-rv5j1201	1387	11	saddle	saddle	NN
cord-022561-rv5j1201	1387	12	horse	horse	NN
cord-022561-rv5j1201	1387	13	gelding	gelding	NN
cord-022561-rv5j1201	1387	14	,	,	,
cord-022561-rv5j1201	1387	15	erythrocyte	erythrocyte	NN
cord-022561-rv5j1201	1387	16	FAD	fad	NN
cord-022561-rv5j1201	1387	17	deficiency	deficiency	NN
cord-022561-rv5j1201	1387	18	is	be	VBZ
cord-022561-rv5j1201	1387	19	a	a	DT
cord-022561-rv5j1201	1387	20	result	result	NN
cord-022561-rv5j1201	1387	21	of	of	IN
cord-022561-rv5j1201	1387	22	an	an	DT
cord-022561-rv5j1201	1387	23	abnormal	abnormal	JJ
cord-022561-rv5j1201	1387	24	riboflavin	riboflavin	NN
cord-022561-rv5j1201	1387	25	kinase	kinase	NN
cord-022561-rv5j1201	1387	26	reaction	reaction	NN
cord-022561-rv5j1201	1387	27	,	,	,
cord-022561-rv5j1201	1387	28	which	which	WDT
cord-022561-rv5j1201	1387	29	is	be	VBZ
cord-022561-rv5j1201	1387	30	the	the	DT
cord-022561-rv5j1201	1387	31	first	first	JJ
cord-022561-rv5j1201	1387	32	reaction	reaction	NN
cord-022561-rv5j1201	1387	33	in	in	IN
cord-022561-rv5j1201	1387	34	converting	convert	VBG
cord-022561-rv5j1201	1387	35	riboflavin	riboflavin	NN
cord-022561-rv5j1201	1387	36	to	to	IN
cord-022561-rv5j1201	1387	37	FAD	fad	NN
cord-022561-rv5j1201	1387	38	.	.	.
cord-022561-rv5j1201	1388	1	Clinicopathologic	Clinicopathologic	NNP
cord-022561-rv5j1201	1388	2	changes	change	NNS
cord-022561-rv5j1201	1388	3	include	include	VBP
cord-022561-rv5j1201	1388	4	persistent	persistent	JJ
cord-022561-rv5j1201	1388	5	methemoglobinemia	methemoglobinemia	NN
cord-022561-rv5j1201	1388	6	of	of	IN
cord-022561-rv5j1201	1388	7	26	26	CD
cord-022561-rv5j1201	1388	8	%	%	NN
cord-022561-rv5j1201	1388	9	to	to	IN
cord-022561-rv5j1201	1388	10	46	46	CD
cord-022561-rv5j1201	1388	11	%	%	NN
cord-022561-rv5j1201	1388	12	,	,	,
cord-022561-rv5j1201	1388	13	eccentrocytosis	eccentrocytosis	NN
cord-022561-rv5j1201	1388	14	,	,	,
cord-022561-rv5j1201	1388	15	a	a	DT
cord-022561-rv5j1201	1388	16	slightly	slightly	RB
cord-022561-rv5j1201	1388	17	decreased	decreased	JJ
cord-022561-rv5j1201	1388	18	or	or	CC
cord-022561-rv5j1201	1388	19	normal	normal	JJ
cord-022561-rv5j1201	1388	20	hematocrit	hematocrit	NN
cord-022561-rv5j1201	1388	21	,	,	,
cord-022561-rv5j1201	1388	22	and	and	CC
cord-022561-rv5j1201	1388	23	erythroid	erythroid	JJ
cord-022561-rv5j1201	1388	24	hyperplasia	hyperplasia	NN
cord-022561-rv5j1201	1388	25	in	in	IN
cord-022561-rv5j1201	1388	26	the	the	DT
cord-022561-rv5j1201	1388	27	bone	bone	NN
cord-022561-rv5j1201	1388	28	marrow	marrow	NN
cord-022561-rv5j1201	1388	29	.	.	.
cord-022561-rv5j1201	1389	1	Equine	equine	JJ
cord-022561-rv5j1201	1389	2	Infectious	Infectious	NNP
cord-022561-rv5j1201	1389	3	Anemia	Anemia	NNP
cord-022561-rv5j1201	1389	4	Virus	Virus	NNP
cord-022561-rv5j1201	1389	5	.	.	.
cord-022561-rv5j1201	1390	1	Equine	equine	JJ
cord-022561-rv5j1201	1390	2	infectious	infectious	JJ
cord-022561-rv5j1201	1390	3	anemia	anemia	NN
cord-022561-rv5j1201	1390	4	virus	virus	NN
cord-022561-rv5j1201	1390	5	(	(	-LRB-
cord-022561-rv5j1201	1390	6	EIAV	EIAV	NNP
cord-022561-rv5j1201	1390	7	)	)	-RRB-
cord-022561-rv5j1201	1390	8	,	,	,
cord-022561-rv5j1201	1390	9	the	the	DT
cord-022561-rv5j1201	1390	10	agent	agent	NN
cord-022561-rv5j1201	1390	11	of	of	IN
cord-022561-rv5j1201	1390	12	equine	equine	JJ
cord-022561-rv5j1201	1390	13	infectious	infectious	JJ
cord-022561-rv5j1201	1390	14	anemia	anemia	NN
cord-022561-rv5j1201	1390	15	,	,	,
cord-022561-rv5j1201	1390	16	is	be	VBZ
cord-022561-rv5j1201	1390	17	a	a	DT
cord-022561-rv5j1201	1390	18	lentivirus	lentivirus	NN
cord-022561-rv5j1201	1390	19	that	that	WDT
cord-022561-rv5j1201	1390	20	infects	infect	VBZ
cord-022561-rv5j1201	1390	21	cells	cell	NNS
cord-022561-rv5j1201	1390	22	of	of	IN
cord-022561-rv5j1201	1390	23	the	the	DT
cord-022561-rv5j1201	1390	24	monocyte	monocyte	JJ
cord-022561-rv5j1201	1390	25	-	-	HYPH
cord-022561-rv5j1201	1390	26	macrophage	macrophage	NN
cord-022561-rv5j1201	1390	27	system	system	NN
cord-022561-rv5j1201	1390	28	in	in	IN
cord-022561-rv5j1201	1390	29	horses	horse	NNS
cord-022561-rv5j1201	1390	30	(	(	-LRB-
cord-022561-rv5j1201	1390	31	also	also	RB
cord-022561-rv5j1201	1390	32	ponies	pony	NNS
cord-022561-rv5j1201	1390	33	,	,	,
cord-022561-rv5j1201	1390	34	donkeys	donkey	NNS
cord-022561-rv5j1201	1390	35	,	,	,
cord-022561-rv5j1201	1390	36	and	and	CC
cord-022561-rv5j1201	1390	37	mules	mule	NNS
cord-022561-rv5j1201	1390	38	)	)	-RRB-
cord-022561-rv5j1201	1390	39	.	.	.
cord-022561-rv5j1201	1391	1	The	the	DT
cord-022561-rv5j1201	1391	2	virus	virus	NN
cord-022561-rv5j1201	1391	3	is	be	VBZ
cord-022561-rv5j1201	1391	4	mechanically	mechanically	RB
cord-022561-rv5j1201	1391	5	transmitted	transmit	VBN
cord-022561-rv5j1201	1391	6	by	by	IN
cord-022561-rv5j1201	1391	7	biting	bite	VBG
cord-022561-rv5j1201	1391	8	flies	fly	NNS
cord-022561-rv5j1201	1391	9	,	,	,
cord-022561-rv5j1201	1391	10	such	such	JJ
cord-022561-rv5j1201	1391	11	as	as	IN
cord-022561-rv5j1201	1391	12	horseflies	horsefly	NNS
cord-022561-rv5j1201	1391	13	and	and	CC
cord-022561-rv5j1201	1391	14	deer	deer	NN
cord-022561-rv5j1201	1391	15	flies	fly	NNS
cord-022561-rv5j1201	1391	16	.	.	.
cord-022561-rv5j1201	1392	1	Less	less	RBR
cord-022561-rv5j1201	1392	2	common	common	JJ
cord-022561-rv5j1201	1392	3	routes	route	NNS
cord-022561-rv5j1201	1392	4	of	of	IN
cord-022561-rv5j1201	1392	5	transmission	transmission	NN
cord-022561-rv5j1201	1392	6	include	include	VBP
cord-022561-rv5j1201	1392	7	blood	blood	NN
cord-022561-rv5j1201	1392	8	transfusions	transfusion	NNS
cord-022561-rv5j1201	1392	9	,	,	,
cord-022561-rv5j1201	1392	10	contaminated	contaminated	JJ
cord-022561-rv5j1201	1392	11	medical	medical	JJ
cord-022561-rv5j1201	1392	12	equipment	equipment	NN
cord-022561-rv5j1201	1392	13	,	,	,
cord-022561-rv5j1201	1392	14	and	and	CC
cord-022561-rv5j1201	1392	15	transplacentally	transplacentally	NN
cord-022561-rv5j1201	1392	16	.	.	.
cord-022561-rv5j1201	1393	1	Disease	Disease	NNP
cord-022561-rv5j1201	1393	2	may	may	MD
cord-022561-rv5j1201	1393	3	present	present	VB
cord-022561-rv5j1201	1393	4	in	in	IN
cord-022561-rv5j1201	1393	5	acute	acute	JJ
cord-022561-rv5j1201	1393	6	,	,	,
cord-022561-rv5j1201	1393	7	subacute	subacute	JJ
cord-022561-rv5j1201	1393	8	,	,	,
cord-022561-rv5j1201	1393	9	and	and	CC
cord-022561-rv5j1201	1393	10	chronic	chronic	JJ
cord-022561-rv5j1201	1393	11	forms	form	NNS
cord-022561-rv5j1201	1393	12	and	and	CC
cord-022561-rv5j1201	1393	13	is	be	VBZ
cord-022561-rv5j1201	1393	14	potentially	potentially	RB
cord-022561-rv5j1201	1393	15	fatal	fatal	JJ
cord-022561-rv5j1201	1393	16	.	.	.
cord-022561-rv5j1201	1394	1	After	after	IN
cord-022561-rv5j1201	1394	2	an	an	DT
cord-022561-rv5j1201	1394	3	acute	acute	JJ
cord-022561-rv5j1201	1394	4	period	period	NN
cord-022561-rv5j1201	1394	5	of	of	IN
cord-022561-rv5j1201	1394	6	fever	fever	NN
cord-022561-rv5j1201	1394	7	,	,	,
cord-022561-rv5j1201	1394	8	depression	depression	NN
cord-022561-rv5j1201	1394	9	,	,	,
cord-022561-rv5j1201	1394	10	and	and	CC
cord-022561-rv5j1201	1394	11	thrombocytopenia	thrombocytopenia	NN
cord-022561-rv5j1201	1394	12	that	that	WDT
cord-022561-rv5j1201	1394	13	lasts	last	VBZ
cord-022561-rv5j1201	1394	14	1	1	CD
cord-022561-rv5j1201	1394	15	to	to	TO
cord-022561-rv5j1201	1394	16	3	3	CD
cord-022561-rv5j1201	1394	17	days	day	NNS
cord-022561-rv5j1201	1394	18	,	,	,
cord-022561-rv5j1201	1394	19	there	there	EX
cord-022561-rv5j1201	1394	20	is	be	VBZ
cord-022561-rv5j1201	1394	21	a	a	DT
cord-022561-rv5j1201	1394	22	prolonged	prolonged	JJ
cord-022561-rv5j1201	1394	23	period	period	NN
cord-022561-rv5j1201	1394	24	of	of	IN
cord-022561-rv5j1201	1394	25	recurrent	recurrent	JJ
cord-022561-rv5j1201	1394	26	fever	fever	NN
cord-022561-rv5j1201	1394	27	,	,	,
cord-022561-rv5j1201	1394	28	thrombocytopenia	thrombocytopenia	NN
cord-022561-rv5j1201	1394	29	,	,	,
cord-022561-rv5j1201	1394	30	and	and	CC
cord-022561-rv5j1201	1394	31	anemia	anemia	NN
cord-022561-rv5j1201	1394	32	.	.	.
cord-022561-rv5j1201	1395	1	In	in	IN
cord-022561-rv5j1201	1395	2	most	most	JJS
cord-022561-rv5j1201	1395	3	cases	case	NNS
cord-022561-rv5j1201	1395	4	,	,	,
cord-022561-rv5j1201	1395	5	clinical	clinical	JJ
cord-022561-rv5j1201	1395	6	disease	disease	NN
cord-022561-rv5j1201	1395	7	subsides	subside	VBZ
cord-022561-rv5j1201	1395	8	within	within	IN
cord-022561-rv5j1201	1395	9	a	a	DT
cord-022561-rv5j1201	1395	10	year	year	NN
cord-022561-rv5j1201	1395	11	,	,	,
cord-022561-rv5j1201	1395	12	and	and	CC
cord-022561-rv5j1201	1395	13	horses	horse	NNS
cord-022561-rv5j1201	1395	14	become	become	VBP
cord-022561-rv5j1201	1395	15	lifelong	lifelong	JJ
cord-022561-rv5j1201	1395	16	carriers	carrier	NNS
cord-022561-rv5j1201	1395	17	and	and	CC
cord-022561-rv5j1201	1395	18	reservoirs	reservoir	NNS
cord-022561-rv5j1201	1395	19	of	of	IN
cord-022561-rv5j1201	1395	20	EIAV	EIAV	NNS
cord-022561-rv5j1201	1395	21	.	.	.
cord-022561-rv5j1201	1396	1	EIAV	EIAV	NNP
cord-022561-rv5j1201	1396	2	causes	cause	VBZ
cord-022561-rv5j1201	1396	3	anemia	anemia	NN
cord-022561-rv5j1201	1396	4	by	by	IN
cord-022561-rv5j1201	1396	5	both	both	DT
cord-022561-rv5j1201	1396	6	immune	immune	NN
cord-022561-rv5j1201	1396	7	-	-	HYPH
cord-022561-rv5j1201	1396	8	mediated	mediate	VBN
cord-022561-rv5j1201	1396	9	hemolysis	hemolysis	NN
cord-022561-rv5j1201	1396	10	and	and	CC
cord-022561-rv5j1201	1396	11	decreased	decrease	VBD
cord-022561-rv5j1201	1396	12	erythropoiesis	erythropoiesis	NN
cord-022561-rv5j1201	1396	13	.	.	.
cord-022561-rv5j1201	1397	1	Hemolysis	Hemolysis	NNP
cord-022561-rv5j1201	1397	2	is	be	VBZ
cord-022561-rv5j1201	1397	3	typically	typically	RB
cord-022561-rv5j1201	1397	4	extravascular	extravascular	JJ
cord-022561-rv5j1201	1397	5	but	but	CC
cord-022561-rv5j1201	1397	6	may	may	MD
cord-022561-rv5j1201	1397	7	have	have	VB
cord-022561-rv5j1201	1397	8	an	an	DT
cord-022561-rv5j1201	1397	9	intravascular	intravascular	JJ
cord-022561-rv5j1201	1397	10	component	component	NN
cord-022561-rv5j1201	1397	11	during	during	IN
cord-022561-rv5j1201	1397	12	the	the	DT
cord-022561-rv5j1201	1397	13	acute	acute	JJ
cord-022561-rv5j1201	1397	14	phase	phase	NN
cord-022561-rv5j1201	1397	15	.	.	.
cord-022561-rv5j1201	1398	1	Decreased	decrease	VBN
cord-022561-rv5j1201	1398	2	erythropoiesis	erythropoiesis	NN
cord-022561-rv5j1201	1398	3	may	may	MD
cord-022561-rv5j1201	1398	4	result	result	VB
cord-022561-rv5j1201	1398	5	from	from	IN
cord-022561-rv5j1201	1398	6	direct	direct	JJ
cord-022561-rv5j1201	1398	7	suppression	suppression	NN
cord-022561-rv5j1201	1398	8	of	of	IN
cord-022561-rv5j1201	1398	9	earlystage	earlystage	NN
cord-022561-rv5j1201	1398	10	erythroid	erythroid	NN
cord-022561-rv5j1201	1398	11	cells	cell	NNS
cord-022561-rv5j1201	1398	12	by	by	IN
cord-022561-rv5j1201	1398	13	the	the	DT
cord-022561-rv5j1201	1398	14	virus	virus	NN
cord-022561-rv5j1201	1398	15	,	,	,
cord-022561-rv5j1201	1398	16	as	as	RB
cord-022561-rv5j1201	1398	17	well	well	RB
cord-022561-rv5j1201	1398	18	as	as	IN
cord-022561-rv5j1201	1398	19	anemia	anemia	NN
cord-022561-rv5j1201	1398	20	of	of	IN
cord-022561-rv5j1201	1398	21	inflammation	inflammation	NN
cord-022561-rv5j1201	1398	22	.	.	.
cord-022561-rv5j1201	1399	1	Thrombocytopenia	Thrombocytopenia	NNP
cord-022561-rv5j1201	1399	2	likely	likely	JJ
cord-022561-rv5j1201	1399	3	results	result	VBZ
cord-022561-rv5j1201	1399	4	from	from	IN
cord-022561-rv5j1201	1399	5	immune	immune	NN
cord-022561-rv5j1201	1399	6	-	-	HYPH
cord-022561-rv5j1201	1399	7	mediated	mediate	VBN
cord-022561-rv5j1201	1399	8	platelet	platelet	NN
cord-022561-rv5j1201	1399	9	destruction	destruction	NN
cord-022561-rv5j1201	1399	10	and	and	CC
cord-022561-rv5j1201	1399	11	suppressed	suppress	VBN
cord-022561-rv5j1201	1399	12	platelet	platelet	NN
cord-022561-rv5j1201	1399	13	production	production	NN
cord-022561-rv5j1201	1399	14	.	.	.
cord-022561-rv5j1201	1400	1	Animals	animal	NNS
cord-022561-rv5j1201	1400	2	dying	die	VBG
cord-022561-rv5j1201	1400	3	during	during	IN
cord-022561-rv5j1201	1400	4	hemolytic	hemolytic	JJ
cord-022561-rv5j1201	1400	5	crises	crisis	NNS
cord-022561-rv5j1201	1400	6	are	be	VBP
cord-022561-rv5j1201	1400	7	pale	pale	JJ
cord-022561-rv5j1201	1400	8	with	with	IN
cord-022561-rv5j1201	1400	9	mucosal	mucosal	JJ
cord-022561-rv5j1201	1400	10	hemorrhages	hemorrhage	NNS
cord-022561-rv5j1201	1400	11	and	and	CC
cord-022561-rv5j1201	1400	12	dependent	dependent	JJ
cord-022561-rv5j1201	1400	13	edema	edema	NN
cord-022561-rv5j1201	1400	14	.	.	.
cord-022561-rv5j1201	1401	1	The	the	DT
cord-022561-rv5j1201	1401	2	spleen	spleen	NNS
cord-022561-rv5j1201	1401	3	and	and	CC
cord-022561-rv5j1201	1401	4	liver	liver	NN
cord-022561-rv5j1201	1401	5	are	be	VBP
cord-022561-rv5j1201	1401	6	enlarged	enlarge	VBN
cord-022561-rv5j1201	1401	7	,	,	,
cord-022561-rv5j1201	1401	8	dark	dark	JJ
cord-022561-rv5j1201	1401	9	,	,	,
cord-022561-rv5j1201	1401	10	and	and	CC
cord-022561-rv5j1201	1401	11	turgid	turgid	JJ
cord-022561-rv5j1201	1401	12	,	,	,
cord-022561-rv5j1201	1401	13	and	and	CC
cord-022561-rv5j1201	1401	14	they	-PRON-	PRP
cord-022561-rv5j1201	1401	15	and	and	CC
cord-022561-rv5j1201	1401	16	other	other	JJ
cord-022561-rv5j1201	1401	17	organs	organ	NNS
cord-022561-rv5j1201	1401	18	have	have	VBP
cord-022561-rv5j1201	1401	19	superficial	superficial	JJ
cord-022561-rv5j1201	1401	20	subcapsular	subcapsular	JJ
cord-022561-rv5j1201	1401	21	hemorrhages	hemorrhage	NNS
cord-022561-rv5j1201	1401	22	.	.	.
cord-022561-rv5j1201	1402	1	Petechiae	Petechiae	NNP
cord-022561-rv5j1201	1402	2	are	be	VBP
cord-022561-rv5j1201	1402	3	evident	evident	JJ
cord-022561-rv5j1201	1402	4	beneath	beneath	IN
cord-022561-rv5j1201	1402	5	the	the	DT
cord-022561-rv5j1201	1402	6	renal	renal	JJ
cord-022561-rv5j1201	1402	7	capsule	capsule	NN
cord-022561-rv5j1201	1402	8	and	and	CC
cord-022561-rv5j1201	1402	9	throughout	throughout	IN
cord-022561-rv5j1201	1402	10	the	the	DT
cord-022561-rv5j1201	1402	11	cortex	cortex	NN
cord-022561-rv5j1201	1402	12	and	and	CC
cord-022561-rv5j1201	1402	13	medulla	medulla	NN
cord-022561-rv5j1201	1402	14	.	.	.
cord-022561-rv5j1201	1403	1	The	the	DT
cord-022561-rv5j1201	1403	2	bone	bone	NN
cord-022561-rv5j1201	1403	3	affected	affect	VBN
cord-022561-rv5j1201	1403	4	animals	animal	NNS
cord-022561-rv5j1201	1403	5	are	be	VBP
cord-022561-rv5j1201	1403	6	not	not	RB
cord-022561-rv5j1201	1403	7	necessarily	necessarily	RB
cord-022561-rv5j1201	1403	8	anemic	anemic	JJ
cord-022561-rv5j1201	1403	9	.	.	.
cord-022561-rv5j1201	1404	1	However	however	RB
cord-022561-rv5j1201	1404	2	,	,	,
cord-022561-rv5j1201	1404	3	acute	acute	JJ
cord-022561-rv5j1201	1404	4	intravascular	intravascular	JJ
cord-022561-rv5j1201	1404	5	hemolytic	hemolytic	JJ
cord-022561-rv5j1201	1404	6	episodes	episode	NNS
cord-022561-rv5j1201	1404	7	may	may	MD
cord-022561-rv5j1201	1404	8	occur	occur	VB
cord-022561-rv5j1201	1404	9	with	with	IN
cord-022561-rv5j1201	1404	10	hyperventilationinduced	hyperventilationinduced	NNP
cord-022561-rv5j1201	1404	11	alkalemia	alkalemia	NNP
cord-022561-rv5j1201	1404	12	.	.	.
cord-022561-rv5j1201	1405	1	Lesions	lesion	NNS
cord-022561-rv5j1201	1405	2	are	be	VBP
cord-022561-rv5j1201	1405	3	typical	typical	JJ
cord-022561-rv5j1201	1405	4	of	of	IN
cord-022561-rv5j1201	1405	5	hemolytic	hemolytic	JJ
cord-022561-rv5j1201	1405	6	anemia	anemia	NN
cord-022561-rv5j1201	1405	7	and	and	CC
cord-022561-rv5j1201	1405	8	include	include	VBP
cord-022561-rv5j1201	1405	9	pale	pale	JJ
cord-022561-rv5j1201	1405	10	mucous	mucous	JJ
cord-022561-rv5j1201	1405	11	membranes	membrane	NNS
cord-022561-rv5j1201	1405	12	,	,	,
cord-022561-rv5j1201	1405	13	icterus	icterus	NN
cord-022561-rv5j1201	1405	14	,	,	,
cord-022561-rv5j1201	1405	15	hepatosplenomegaly	hepatosplenomegaly	NNP
cord-022561-rv5j1201	1405	16	,	,	,
cord-022561-rv5j1201	1405	17	and	and	CC
cord-022561-rv5j1201	1405	18	dark	dark	JJ
cord-022561-rv5j1201	1405	19	red	red	JJ
cord-022561-rv5j1201	1405	20	urine	urine	NN
cord-022561-rv5j1201	1405	21	with	with	IN
cord-022561-rv5j1201	1405	22	microscopic	microscopic	JJ
cord-022561-rv5j1201	1405	23	EMH	EMH	NNP
cord-022561-rv5j1201	1405	24	and	and	CC
cord-022561-rv5j1201	1405	25	marrow	marrow	NN
cord-022561-rv5j1201	1405	26	erythroid	erythroid	NN
cord-022561-rv5j1201	1405	27	hyperplasia	hyperplasia	NN
cord-022561-rv5j1201	1405	28	.	.	.
cord-022561-rv5j1201	1406	1	A	a	DT
cord-022561-rv5j1201	1406	2	single	single	JJ
cord-022561-rv5j1201	1406	3	DNA	dna	NN
cord-022561-rv5j1201	1406	4	-	-	HYPH
cord-022561-rv5j1201	1406	5	based	base	VBN
cord-022561-rv5j1201	1406	6	test	test	NN
cord-022561-rv5j1201	1406	7	is	be	VBZ
cord-022561-rv5j1201	1406	8	available	available	JJ
cord-022561-rv5j1201	1406	9	to	to	TO
cord-022561-rv5j1201	1406	10	detect	detect	VB
cord-022561-rv5j1201	1406	11	the	the	DT
cord-022561-rv5j1201	1406	12	common	common	JJ
cord-022561-rv5j1201	1406	13	mutation	mutation	NN
cord-022561-rv5j1201	1406	14	.	.	.
cord-022561-rv5j1201	1407	1	Erythrocyte	Erythrocyte	NNP
cord-022561-rv5j1201	1407	2	Structural	Structural	NNP
cord-022561-rv5j1201	1407	3	Abnormalities	Abnormalities	NNPS
cord-022561-rv5j1201	1407	4	.	.	.
cord-022561-rv5j1201	1408	1	Congenital	congenital	JJ
cord-022561-rv5j1201	1408	2	erythrocyte	erythrocyte	NN
cord-022561-rv5j1201	1408	3	structural	structural	JJ
cord-022561-rv5j1201	1408	4	abnormalities	abnormality	NNS
cord-022561-rv5j1201	1408	5	may	may	MD
cord-022561-rv5j1201	1408	6	occur	occur	VB
cord-022561-rv5j1201	1408	7	with	with	IN
cord-022561-rv5j1201	1408	8	abnormal	abnormal	JJ
cord-022561-rv5j1201	1408	9	membrane	membrane	NN
cord-022561-rv5j1201	1408	10	composition	composition	NN
cord-022561-rv5j1201	1408	11	or	or	CC
cord-022561-rv5j1201	1408	12	defective	defective	JJ
cord-022561-rv5j1201	1408	13	proteins	protein	NNS
cord-022561-rv5j1201	1408	14	within	within	IN
cord-022561-rv5j1201	1408	15	the	the	DT
cord-022561-rv5j1201	1408	16	membrane	membrane	NN
cord-022561-rv5j1201	1408	17	or	or	CC
cord-022561-rv5j1201	1408	18	cytoskeleton	cytoskeleton	NN
cord-022561-rv5j1201	1408	19	.	.	.
cord-022561-rv5j1201	1409	1	Some	some	DT
cord-022561-rv5j1201	1409	2	of	of	IN
cord-022561-rv5j1201	1409	3	these	these	DT
cord-022561-rv5j1201	1409	4	morphologic	morphologic	JJ
cord-022561-rv5j1201	1409	5	changes	change	NNS
cord-022561-rv5j1201	1409	6	occur	occur	VBP
cord-022561-rv5j1201	1409	7	concurrently	concurrently	RB
cord-022561-rv5j1201	1409	8	with	with	IN
cord-022561-rv5j1201	1409	9	clinical	clinical	JJ
cord-022561-rv5j1201	1409	10	disease	disease	NN
cord-022561-rv5j1201	1409	11	,	,	,
cord-022561-rv5j1201	1409	12	but	but	CC
cord-022561-rv5j1201	1409	13	others	other	NNS
cord-022561-rv5j1201	1409	14	do	do	VBP
cord-022561-rv5j1201	1409	15	not	not	RB
cord-022561-rv5j1201	1409	16	.	.	.
cord-022561-rv5j1201	1410	1	Hereditary	hereditary	JJ
cord-022561-rv5j1201	1410	2	stomatocytosis	stomatocytosis	NN
cord-022561-rv5j1201	1410	3	is	be	VBZ
cord-022561-rv5j1201	1410	4	recognized	recognize	VBN
cord-022561-rv5j1201	1410	5	in	in	IN
cord-022561-rv5j1201	1410	6	Alaskan	alaskan	JJ
cord-022561-rv5j1201	1410	7	malamutes	malamute	NNS
cord-022561-rv5j1201	1410	8	,	,	,
cord-022561-rv5j1201	1410	9	Drentse	Drentse	NNP
cord-022561-rv5j1201	1410	10	patrijshonds	patrijshond	NNS
cord-022561-rv5j1201	1410	11	,	,	,
cord-022561-rv5j1201	1410	12	and	and	CC
cord-022561-rv5j1201	1410	13	schnauzers	schnauzer	NNS
cord-022561-rv5j1201	1410	14	.	.	.
cord-022561-rv5j1201	1411	1	The	the	DT
cord-022561-rv5j1201	1411	2	specific	specific	JJ
cord-022561-rv5j1201	1411	3	defects	defect	NNS
cord-022561-rv5j1201	1411	4	are	be	VBP
cord-022561-rv5j1201	1411	5	not	not	RB
cord-022561-rv5j1201	1411	6	known	know	VBN
cord-022561-rv5j1201	1411	7	,	,	,
cord-022561-rv5j1201	1411	8	but	but	CC
cord-022561-rv5j1201	1411	9	they	-PRON-	PRP
cord-022561-rv5j1201	1411	10	are	be	VBP
cord-022561-rv5j1201	1411	11	likely	likely	RB
cord-022561-rv5j1201	1411	12	different	different	JJ
cord-022561-rv5j1201	1411	13	in	in	IN
cord-022561-rv5j1201	1411	14	the	the	DT
cord-022561-rv5j1201	1411	15	various	various	JJ
cord-022561-rv5j1201	1411	16	dog	dog	NN
cord-022561-rv5j1201	1411	17	breeds	breed	NNS
cord-022561-rv5j1201	1411	18	.	.	.
cord-022561-rv5j1201	1412	1	However	however	RB
cord-022561-rv5j1201	1412	2	,	,	,
cord-022561-rv5j1201	1412	3	all	all	DT
cord-022561-rv5j1201	1412	4	affected	affect	VBN
cord-022561-rv5j1201	1412	5	dogs	dog	NNS
cord-022561-rv5j1201	1412	6	have	have	VBP
cord-022561-rv5j1201	1412	7	stomatocytes	stomatocyte	NNS
cord-022561-rv5j1201	1412	8	on	on	IN
cord-022561-rv5j1201	1412	9	blood	blood	NN
cord-022561-rv5j1201	1412	10	smear	smear	NN
cord-022561-rv5j1201	1412	11	evaluation	evaluation	NN
cord-022561-rv5j1201	1412	12	,	,	,
cord-022561-rv5j1201	1412	13	as	as	IN
cord-022561-rv5j1201	1412	14	identified	identify	VBN
cord-022561-rv5j1201	1412	15	by	by	IN
cord-022561-rv5j1201	1412	16	their	-PRON-	PRP$
cord-022561-rv5j1201	1412	17	slit	slit	NN
cord-022561-rv5j1201	1412	18	-	-	HYPH
cord-022561-rv5j1201	1412	19	shaped	shaped	JJ
cord-022561-rv5j1201	1412	20	area	area	NN
cord-022561-rv5j1201	1412	21	of	of	IN
cord-022561-rv5j1201	1412	22	central	central	JJ
cord-022561-rv5j1201	1412	23	pallor	pallor	NN
cord-022561-rv5j1201	1412	24	.	.	.
cord-022561-rv5j1201	1413	1	Erythrocytes	erythrocyte	NNS
cord-022561-rv5j1201	1413	2	also	also	RB
cord-022561-rv5j1201	1413	3	have	have	VBP
cord-022561-rv5j1201	1413	4	increased	increase	VBN
cord-022561-rv5j1201	1413	5	osmotic	osmotic	JJ
cord-022561-rv5j1201	1413	6	fragility	fragility	NN
cord-022561-rv5j1201	1413	7	and	and	CC
cord-022561-rv5j1201	1413	8	decreased	decrease	VBD
cord-022561-rv5j1201	1413	9	survival	survival	NN
cord-022561-rv5j1201	1413	10	.	.	.
cord-022561-rv5j1201	1414	1	Schnauzers	schnauzer	NNS
cord-022561-rv5j1201	1414	2	are	be	VBP
cord-022561-rv5j1201	1414	3	clinically	clinically	RB
cord-022561-rv5j1201	1414	4	healthy	healthy	JJ
cord-022561-rv5j1201	1414	5	and	and	CC
cord-022561-rv5j1201	1414	6	not	not	RB
cord-022561-rv5j1201	1414	7	anemic	anemic	JJ
cord-022561-rv5j1201	1414	8	but	but	CC
cord-022561-rv5j1201	1414	9	do	do	VBP
cord-022561-rv5j1201	1414	10	have	have	VB
cord-022561-rv5j1201	1414	11	reticulocytosis	reticulocytosis	NN
cord-022561-rv5j1201	1414	12	,	,	,
cord-022561-rv5j1201	1414	13	suggesting	suggest	VBG
cord-022561-rv5j1201	1414	14	that	that	IN
cord-022561-rv5j1201	1414	15	the	the	DT
cord-022561-rv5j1201	1414	16	hemolytic	hemolytic	JJ
cord-022561-rv5j1201	1414	17	anemia	anemia	NN
cord-022561-rv5j1201	1414	18	is	be	VBZ
cord-022561-rv5j1201	1414	19	compensated	compensate	VBN
cord-022561-rv5j1201	1414	20	by	by	IN
cord-022561-rv5j1201	1414	21	erythroid	erythroid	JJ
cord-022561-rv5j1201	1414	22	hyperplasia	hyperplasia	NN
cord-022561-rv5j1201	1414	23	.	.	.
cord-022561-rv5j1201	1415	1	Mild	mild	JJ
cord-022561-rv5j1201	1415	2	to	to	IN
cord-022561-rv5j1201	1415	3	marked	marked	JJ
cord-022561-rv5j1201	1415	4	hemolytic	hemolytic	JJ
cord-022561-rv5j1201	1415	5	anemia	anemia	NN
cord-022561-rv5j1201	1415	6	is	be	VBZ
cord-022561-rv5j1201	1415	7	documented	document	VBN
cord-022561-rv5j1201	1415	8	in	in	IN
cord-022561-rv5j1201	1415	9	Alaskan	alaskan	JJ
cord-022561-rv5j1201	1415	10	malamutes	malamute	NNS
cord-022561-rv5j1201	1415	11	and	and	CC
cord-022561-rv5j1201	1415	12	Drentse	Drentse	NNP
cord-022561-rv5j1201	1415	13	patrijshonds	patrijshond	NNS
cord-022561-rv5j1201	1415	14	.	.	.
cord-022561-rv5j1201	1416	1	Alaskan	alaskan	JJ
cord-022561-rv5j1201	1416	2	malamutes	malamute	NNS
cord-022561-rv5j1201	1416	3	have	have	VBP
cord-022561-rv5j1201	1416	4	concurrent	concurrent	JJ
cord-022561-rv5j1201	1416	5	short	short	JJ
cord-022561-rv5j1201	1416	6	-	-	HYPH
cord-022561-rv5j1201	1416	7	limb	limb	NN
cord-022561-rv5j1201	1416	8	dwarfism	dwarfism	NN
cord-022561-rv5j1201	1416	9	,	,	,
cord-022561-rv5j1201	1416	10	and	and	CC
cord-022561-rv5j1201	1416	11	Drentse	Drentse	NNP
cord-022561-rv5j1201	1416	12	patrijshonds	patrijshond	NNS
cord-022561-rv5j1201	1416	13	have	have	VBP
cord-022561-rv5j1201	1416	14	hypertrophic	hypertrophic	JJ
cord-022561-rv5j1201	1416	15	gastritis	gastritis	NN
cord-022561-rv5j1201	1416	16	and	and	CC
cord-022561-rv5j1201	1416	17	polycystic	polycystic	JJ
cord-022561-rv5j1201	1416	18	kidney	kidney	NN
cord-022561-rv5j1201	1416	19	disease	disease	NN
cord-022561-rv5j1201	1416	20	.	.	.
cord-022561-rv5j1201	1417	1	Other	other	JJ
cord-022561-rv5j1201	1417	2	(	(	-LRB-
cord-022561-rv5j1201	1417	3	presumably	presumably	RB
cord-022561-rv5j1201	1417	4	heritable	heritable	JJ
cord-022561-rv5j1201	1417	5	)	)	-RRB-
cord-022561-rv5j1201	1417	6	erythrocyte	erythrocyte	NN
cord-022561-rv5j1201	1417	7	abnormalities	abnormality	NNS
cord-022561-rv5j1201	1417	8	in	in	IN
cord-022561-rv5j1201	1417	9	dogs	dog	NNS
cord-022561-rv5j1201	1417	10	that	that	WDT
cord-022561-rv5j1201	1417	11	do	do	VBP
cord-022561-rv5j1201	1417	12	not	not	RB
cord-022561-rv5j1201	1417	13	have	have	VB
cord-022561-rv5j1201	1417	14	clinical	clinical	JJ
cord-022561-rv5j1201	1417	15	signs	sign	NNS
cord-022561-rv5j1201	1417	16	include	include	VBP
cord-022561-rv5j1201	1417	17	elliptocytosis	elliptocytosis	NN
cord-022561-rv5j1201	1417	18	caused	cause	VBN
cord-022561-rv5j1201	1417	19	by	by	IN
cord-022561-rv5j1201	1417	20	band	band	NN
cord-022561-rv5j1201	1417	21	4.1	4.1	CD
cord-022561-rv5j1201	1417	22	deficiency	deficiency	NN
cord-022561-rv5j1201	1417	23	or	or	CC
cord-022561-rv5j1201	1417	24	β	β	NN
cord-022561-rv5j1201	1417	25	-	-	HYPH
cord-022561-rv5j1201	1417	26	spectrin	spectrin	NNP
cord-022561-rv5j1201	1417	27	mutation	mutation	NN
cord-022561-rv5j1201	1417	28	,	,	,
cord-022561-rv5j1201	1417	29	and	and	CC
cord-022561-rv5j1201	1417	30	familial	familial	JJ
cord-022561-rv5j1201	1417	31	macrocytosis	macrocytosis	NN
cord-022561-rv5j1201	1417	32	and	and	CC
cord-022561-rv5j1201	1417	33	dyshematopoiesis	dyshematopoiesis	NN
cord-022561-rv5j1201	1417	34	in	in	IN
cord-022561-rv5j1201	1417	35	poodles	poodle	NNS
cord-022561-rv5j1201	1417	36	.	.	.
cord-022561-rv5j1201	1418	1	Scott	Scott	NNP
cord-022561-rv5j1201	1418	2	's	's	POS
cord-022561-rv5j1201	1418	3	Syndrome	Syndrome	NNP
cord-022561-rv5j1201	1418	4	.	.	.
cord-022561-rv5j1201	1419	1	An	an	DT
cord-022561-rv5j1201	1419	2	inherited	inherit	VBN
cord-022561-rv5j1201	1419	3	thrombopathy	thrombopathy	NN
cord-022561-rv5j1201	1419	4	resembling	resemble	VBG
cord-022561-rv5j1201	1419	5	Scott	Scott	NNP
cord-022561-rv5j1201	1419	6	's	's	POS
cord-022561-rv5j1201	1419	7	syndrome	syndrome	NN
cord-022561-rv5j1201	1419	8	in	in	IN
cord-022561-rv5j1201	1419	9	human	human	JJ
cord-022561-rv5j1201	1419	10	beings	being	NNS
cord-022561-rv5j1201	1419	11	,	,	,
cord-022561-rv5j1201	1419	12	in	in	IN
cord-022561-rv5j1201	1419	13	which	which	WDT
cord-022561-rv5j1201	1419	14	platelets	platelet	NNS
cord-022561-rv5j1201	1419	15	lack	lack	VBP
cord-022561-rv5j1201	1419	16	normal	normal	JJ
cord-022561-rv5j1201	1419	17	procoagulant	procoagulant	NN
cord-022561-rv5j1201	1419	18	activity	activity	NN
cord-022561-rv5j1201	1419	19	,	,	,
cord-022561-rv5j1201	1419	20	has	have	VBZ
cord-022561-rv5j1201	1419	21	been	be	VBN
cord-022561-rv5j1201	1419	22	recognized	recognize	VBN
cord-022561-rv5j1201	1419	23	in	in	IN
cord-022561-rv5j1201	1419	24	a	a	DT
cord-022561-rv5j1201	1419	25	family	family	NN
cord-022561-rv5j1201	1419	26	of	of	IN
cord-022561-rv5j1201	1419	27	German	german	JJ
cord-022561-rv5j1201	1419	28	shepherd	shepherd	NN
cord-022561-rv5j1201	1419	29	dogs	dog	NNS
cord-022561-rv5j1201	1419	30	.	.	.
cord-022561-rv5j1201	1420	1	The	the	DT
cord-022561-rv5j1201	1420	2	specific	specific	JJ
cord-022561-rv5j1201	1420	3	defect	defect	NN
cord-022561-rv5j1201	1420	4	in	in	IN
cord-022561-rv5j1201	1420	5	these	these	DT
cord-022561-rv5j1201	1420	6	dogs	dog	NNS
cord-022561-rv5j1201	1420	7	has	have	VBZ
cord-022561-rv5j1201	1420	8	not	not	RB
cord-022561-rv5j1201	1420	9	been	be	VBN
cord-022561-rv5j1201	1420	10	identified	identify	VBN
cord-022561-rv5j1201	1420	11	on	on	IN
cord-022561-rv5j1201	1420	12	the	the	DT
cord-022561-rv5j1201	1420	13	molecular	molecular	JJ
cord-022561-rv5j1201	1420	14	level	level	NN
cord-022561-rv5j1201	1420	15	but	but	CC
cord-022561-rv5j1201	1420	16	involves	involve	VBZ
cord-022561-rv5j1201	1420	17	impaired	impaired	JJ
cord-022561-rv5j1201	1420	18	expression	expression	NN
cord-022561-rv5j1201	1420	19	of	of	IN
cord-022561-rv5j1201	1420	20	phosphatidylserine	phosphatidylserine	NN
cord-022561-rv5j1201	1420	21	on	on	IN
cord-022561-rv5j1201	1420	22	the	the	DT
cord-022561-rv5j1201	1420	23	platelet	platelet	NN
cord-022561-rv5j1201	1420	24	surface	surface	NN
cord-022561-rv5j1201	1420	25	.	.	.
cord-022561-rv5j1201	1421	1	Affected	affected	JJ
cord-022561-rv5j1201	1421	2	dogs	dog	NNS
cord-022561-rv5j1201	1421	3	have	have	VBP
cord-022561-rv5j1201	1421	4	a	a	DT
cord-022561-rv5j1201	1421	5	mild	mild	JJ
cord-022561-rv5j1201	1421	6	to	to	TO
cord-022561-rv5j1201	1421	7	moderate	moderate	VB
cord-022561-rv5j1201	1421	8	clinical	clinical	JJ
cord-022561-rv5j1201	1421	9	bleeding	bleeding	NN
cord-022561-rv5j1201	1421	10	tendency	tendency	NN
cord-022561-rv5j1201	1421	11	characterized	characterize	VBN
cord-022561-rv5j1201	1421	12	by	by	IN
cord-022561-rv5j1201	1421	13	epistaxis	epistaxis	NNP
cord-022561-rv5j1201	1421	14	,	,	,
cord-022561-rv5j1201	1421	15	hyphema	hyphema	NNP
cord-022561-rv5j1201	1421	16	,	,	,
cord-022561-rv5j1201	1421	17	intramuscular	intramuscular	JJ
cord-022561-rv5j1201	1421	18	hematoma	hematoma	NN
cord-022561-rv5j1201	1421	19	formation	formation	NN
cord-022561-rv5j1201	1421	20	,	,	,
cord-022561-rv5j1201	1421	21	and	and	CC
cord-022561-rv5j1201	1421	22	increased	increase	VBN
cord-022561-rv5j1201	1421	23	hemorrhage	hemorrhage	NN
cord-022561-rv5j1201	1421	24	with	with	IN
cord-022561-rv5j1201	1421	25	surgery	surgery	NN
cord-022561-rv5j1201	1421	26	.	.	.
cord-022561-rv5j1201	1422	1	Macrothrombocytopenia	Macrothrombocytopenia	NNP
cord-022561-rv5j1201	1422	2	.	.	.
cord-022561-rv5j1201	1423	1	Macrothrombocytopenia	Macrothrombocytopenia	NNP
cord-022561-rv5j1201	1423	2	is	be	VBZ
cord-022561-rv5j1201	1423	3	an	an	DT
cord-022561-rv5j1201	1423	4	inherited	inherit	VBN
cord-022561-rv5j1201	1423	5	condition	condition	NN
cord-022561-rv5j1201	1423	6	in	in	IN
cord-022561-rv5j1201	1423	7	Cavalier	Cavalier	NNP
cord-022561-rv5j1201	1423	8	King	King	NNP
cord-022561-rv5j1201	1423	9	Charles	Charles	NNP
cord-022561-rv5j1201	1423	10	spaniels	spaniel	NNS
cord-022561-rv5j1201	1423	11	in	in	IN
cord-022561-rv5j1201	1423	12	which	which	WDT
cord-022561-rv5j1201	1423	13	there	there	EX
cord-022561-rv5j1201	1423	14	are	be	VBP
cord-022561-rv5j1201	1423	15	lower	low	JJR
cord-022561-rv5j1201	1423	16	than	than	IN
cord-022561-rv5j1201	1423	17	normal	normal	JJ
cord-022561-rv5j1201	1423	18	concentrations	concentration	NNS
cord-022561-rv5j1201	1423	19	of	of	IN
cord-022561-rv5j1201	1423	20	platelets	platelet	NNS
cord-022561-rv5j1201	1423	21	with	with	IN
cord-022561-rv5j1201	1423	22	enlarged	enlarged	JJ
cord-022561-rv5j1201	1423	23	and	and	CC
cord-022561-rv5j1201	1423	24	giant	giant	JJ
cord-022561-rv5j1201	1423	25	platelets	platelet	NNS
cord-022561-rv5j1201	1423	26	.	.	.
cord-022561-rv5j1201	1424	1	The	the	DT
cord-022561-rv5j1201	1424	2	condition	condition	NN
cord-022561-rv5j1201	1424	3	is	be	VBZ
cord-022561-rv5j1201	1424	4	caused	cause	VBN
cord-022561-rv5j1201	1424	5	by	by	IN
cord-022561-rv5j1201	1424	6	defective	defective	JJ
cord-022561-rv5j1201	1424	7	β	β	NNP
cord-022561-rv5j1201	1424	8	1	1	CD
cord-022561-rv5j1201	1424	9	-tubulin	-tubulin	NNP
cord-022561-rv5j1201	1424	10	,	,	,
cord-022561-rv5j1201	1424	11	which	which	WDT
cord-022561-rv5j1201	1424	12	results	result	VBZ
cord-022561-rv5j1201	1424	13	in	in	IN
cord-022561-rv5j1201	1424	14	impaired	impaired	JJ
cord-022561-rv5j1201	1424	15	microtubule	microtubule	NN
cord-022561-rv5j1201	1424	16	assembly	assembly	NN
cord-022561-rv5j1201	1424	17	.	.	.
cord-022561-rv5j1201	1425	1	Affected	affected	JJ
cord-022561-rv5j1201	1425	2	dogs	dog	NNS
cord-022561-rv5j1201	1425	3	are	be	VBP
cord-022561-rv5j1201	1425	4	asymptomatic	asymptomatic	JJ
cord-022561-rv5j1201	1425	5	but	but	CC
cord-022561-rv5j1201	1425	6	may	may	MD
cord-022561-rv5j1201	1425	7	have	have	VB
cord-022561-rv5j1201	1425	8	abnormal	abnormal	JJ
cord-022561-rv5j1201	1425	9	platelet	platelet	NN
cord-022561-rv5j1201	1425	10	aggregation	aggregation	NN
cord-022561-rv5j1201	1425	11	in	in	IN
cord-022561-rv5j1201	1425	12	vitro	vitro	FW
cord-022561-rv5j1201	1425	13	.	.	.
cord-022561-rv5j1201	1426	1	Canine	canine	JJ
cord-022561-rv5j1201	1426	2	Distemper	Distemper	NNP
cord-022561-rv5j1201	1426	3	.	.	.
cord-022561-rv5j1201	1427	1	Canine	canine	JJ
cord-022561-rv5j1201	1427	2	distemper	distemper	NN
cord-022561-rv5j1201	1427	3	virus	virus	NN
cord-022561-rv5j1201	1427	4	preferentially	preferentially	RB
cord-022561-rv5j1201	1427	5	infects	infect	VBZ
cord-022561-rv5j1201	1427	6	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	1427	7	,	,	,
cord-022561-rv5j1201	1427	8	epithelial	epithelial	JJ
cord-022561-rv5j1201	1427	9	,	,	,
cord-022561-rv5j1201	1427	10	and	and	CC
cord-022561-rv5j1201	1427	11	nervous	nervous	JJ
cord-022561-rv5j1201	1427	12	cells	cell	NNS
cord-022561-rv5j1201	1427	13	and	and	CC
cord-022561-rv5j1201	1427	14	is	be	VBZ
cord-022561-rv5j1201	1427	15	presented	present	VBN
cord-022561-rv5j1201	1427	16	in	in	IN
cord-022561-rv5j1201	1427	17	greater	great	JJR
cord-022561-rv5j1201	1427	18	detail	detail	NN
cord-022561-rv5j1201	1427	19	in	in	IN
cord-022561-rv5j1201	1427	20	the	the	DT
cord-022561-rv5j1201	1427	21	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	1427	22	section	section	NN
cord-022561-rv5j1201	1427	23	.	.	.
cord-022561-rv5j1201	1428	1	Canine	canine	JJ
cord-022561-rv5j1201	1428	2	distemper	distemper	NN
cord-022561-rv5j1201	1428	3	virus	virus	NN
cord-022561-rv5j1201	1428	4	may	may	MD
cord-022561-rv5j1201	1428	5	also	also	RB
cord-022561-rv5j1201	1428	6	infect	infect	VB
cord-022561-rv5j1201	1428	7	other	other	JJ
cord-022561-rv5j1201	1428	8	hematopoietic	hematopoietic	JJ
cord-022561-rv5j1201	1428	9	cells	cell	NNS
cord-022561-rv5j1201	1428	10	,	,	,
cord-022561-rv5j1201	1428	11	including	include	VBG
cord-022561-rv5j1201	1428	12	erythrocytes	erythrocyte	NNS
cord-022561-rv5j1201	1428	13	,	,	,
cord-022561-rv5j1201	1428	14	nonlymphoid	nonlymphoid	NNP
cord-022561-rv5j1201	1428	15	leukocytes	leukocyte	NNS
cord-022561-rv5j1201	1428	16	,	,	,
cord-022561-rv5j1201	1428	17	and	and	CC
cord-022561-rv5j1201	1428	18	platelets	platelet	NNS
cord-022561-rv5j1201	1428	19	(	(	-LRB-
cord-022561-rv5j1201	1428	20	Fig	Fig	NNP
cord-022561-rv5j1201	1428	21	.	.	.
cord-022561-rv5j1201	1428	22	13	13	CD
cord-022561-rv5j1201	1428	23	-	-	SYM
cord-022561-rv5j1201	1428	24	33	33	CD
cord-022561-rv5j1201	1428	25	)	)	-RRB-
cord-022561-rv5j1201	1428	26	,	,	,
cord-022561-rv5j1201	1428	27	and	and	CC
cord-022561-rv5j1201	1428	28	can	can	MD
cord-022561-rv5j1201	1428	29	cause	cause	VB
cord-022561-rv5j1201	1428	30	decreased	decrease	VBN
cord-022561-rv5j1201	1428	31	peripheral	peripheral	JJ
cord-022561-rv5j1201	1428	32	blood	blood	NN
cord-022561-rv5j1201	1428	33	concentrations	concentration	NNS
cord-022561-rv5j1201	1428	34	of	of	IN
cord-022561-rv5j1201	1428	35	neutrophils	neutrophil	NNS
cord-022561-rv5j1201	1428	36	,	,	,
cord-022561-rv5j1201	1428	37	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	1428	38	,	,	,
cord-022561-rv5j1201	1428	39	monocytes	monocyte	NNS
cord-022561-rv5j1201	1428	40	,	,	,
cord-022561-rv5j1201	1428	41	and	and	CC
cord-022561-rv5j1201	1428	42	platelets	platelet	NNS
cord-022561-rv5j1201	1428	43	during	during	IN
cord-022561-rv5j1201	1428	44	viremia	viremia	NN
cord-022561-rv5j1201	1428	45	.	.	.
cord-022561-rv5j1201	1429	1	The	the	DT
cord-022561-rv5j1201	1429	2	thrombocytopenia	thrombocytopenia	NN
cord-022561-rv5j1201	1429	3	is	be	VBZ
cord-022561-rv5j1201	1429	4	a	a	DT
cord-022561-rv5j1201	1429	5	result	result	NN
cord-022561-rv5j1201	1429	6	of	of	IN
cord-022561-rv5j1201	1429	7	virus	virus	NN
cord-022561-rv5j1201	1429	8	-	-	HYPH
cord-022561-rv5j1201	1429	9	antibody	antibody	NN
cord-022561-rv5j1201	1429	10	immune	immune	JJ
cord-022561-rv5j1201	1429	11	complexes	complex	NNS
cord-022561-rv5j1201	1429	12	on	on	IN
cord-022561-rv5j1201	1429	13	platelet	platelet	NN
cord-022561-rv5j1201	1429	14	membranes	membrane	NNS
cord-022561-rv5j1201	1429	15	and	and	CC
cord-022561-rv5j1201	1429	16	direct	direct	JJ
cord-022561-rv5j1201	1429	17	viral	viral	JJ
cord-022561-rv5j1201	1429	18	infection	infection	NN
cord-022561-rv5j1201	1429	19	of	of	IN
cord-022561-rv5j1201	1429	20	megakaryocytes	megakaryocyte	NNS
cord-022561-rv5j1201	1429	21	.	.	.
cord-022561-rv5j1201	1430	1	Increased	increase	VBN
cord-022561-rv5j1201	1430	2	Erythrocyte	Erythrocyte	NNP
cord-022561-rv5j1201	1430	3	Osmotic	osmotic	JJ
cord-022561-rv5j1201	1430	4	Fragility	Fragility	NNP
cord-022561-rv5j1201	1430	5	.	.	.
cord-022561-rv5j1201	1431	1	A	a	DT
cord-022561-rv5j1201	1431	2	condition	condition	NN
cord-022561-rv5j1201	1431	3	characterized	characterize	VBN
cord-022561-rv5j1201	1431	4	by	by	IN
cord-022561-rv5j1201	1431	5	increased	increase	VBN
cord-022561-rv5j1201	1431	6	erythrocyte	erythrocyte	NN
cord-022561-rv5j1201	1431	7	osmotic	osmotic	JJ
cord-022561-rv5j1201	1431	8	fragility	fragility	NN
cord-022561-rv5j1201	1431	9	has	have	VBZ
cord-022561-rv5j1201	1431	10	been	be	VBN
cord-022561-rv5j1201	1431	11	described	describe	VBN
cord-022561-rv5j1201	1431	12	in	in	IN
cord-022561-rv5j1201	1431	13	Abyssinian	abyssinian	JJ
cord-022561-rv5j1201	1431	14	and	and	CC
cord-022561-rv5j1201	1431	15	Somali	somali	JJ
cord-022561-rv5j1201	1431	16	cats	cat	NNS
cord-022561-rv5j1201	1431	17	.	.	.
cord-022561-rv5j1201	1432	1	The	the	DT
cord-022561-rv5j1201	1432	2	specific	specific	JJ
cord-022561-rv5j1201	1432	3	defect	defect	NN
cord-022561-rv5j1201	1432	4	has	have	VBZ
cord-022561-rv5j1201	1432	5	and	and	CC
cord-022561-rv5j1201	1432	6	degeneration	degeneration	NN
cord-022561-rv5j1201	1432	7	)	)	-RRB-
cord-022561-rv5j1201	1432	8	and	and	CC
cord-022561-rv5j1201	1432	9	increased	increase	VBN
cord-022561-rv5j1201	1432	10	thrombopoiesis	thrombopoiesis	NNP
cord-022561-rv5j1201	1432	11	(	(	-LRB-
cord-022561-rv5j1201	1432	12	megakaryocytic	megakaryocytic	JJ
cord-022561-rv5j1201	1432	13	hyperplasia	hyperplasia	NNP
cord-022561-rv5j1201	1432	14	,	,	,
cord-022561-rv5j1201	1432	15	increased	increase	VBN
cord-022561-rv5j1201	1432	16	numbers	number	NNS
cord-022561-rv5j1201	1432	17	of	of	IN
cord-022561-rv5j1201	1432	18	immature	immature	JJ
cord-022561-rv5j1201	1432	19	megakaryocytes	megakaryocyte	NNS
cord-022561-rv5j1201	1432	20	)	)	-RRB-
cord-022561-rv5j1201	1432	21	in	in	IN
cord-022561-rv5j1201	1432	22	the	the	DT
cord-022561-rv5j1201	1432	23	bone	bone	NN
cord-022561-rv5j1201	1432	24	marrow	marrow	NN
cord-022561-rv5j1201	1432	25	has	have	VBZ
cord-022561-rv5j1201	1432	26	been	be	VBN
cord-022561-rv5j1201	1432	27	reported	report	VBN
cord-022561-rv5j1201	1432	28	in	in	IN
cord-022561-rv5j1201	1432	29	type	type	NN
cord-022561-rv5j1201	1432	30	II	II	NNP
cord-022561-rv5j1201	1432	31	BVDV	BVDV	NNP
cord-022561-rv5j1201	1432	32	-	-	HYPH
cord-022561-rv5j1201	1432	33	infected	infect	VBN
cord-022561-rv5j1201	1432	34	animals	animal	NNS
cord-022561-rv5j1201	1432	35	,	,	,
cord-022561-rv5j1201	1432	36	including	include	VBG
cord-022561-rv5j1201	1432	37	concurrent	concurrent	JJ
cord-022561-rv5j1201	1432	38	megakaryocyte	megakaryocyte	NNP
cord-022561-rv5j1201	1432	39	necrosis	necrosis	NN
cord-022561-rv5j1201	1432	40	and	and	CC
cord-022561-rv5j1201	1432	41	hyperplasia	hyperplasia	NN
cord-022561-rv5j1201	1432	42	in	in	IN
cord-022561-rv5j1201	1432	43	some	some	DT
cord-022561-rv5j1201	1432	44	experimental	experimental	JJ
cord-022561-rv5j1201	1432	45	subjects	subject	NNS
cord-022561-rv5j1201	1432	46	.	.	.
cord-022561-rv5j1201	1433	1	Calves	calf	NNS
cord-022561-rv5j1201	1433	2	infected	infect	VBN
cord-022561-rv5j1201	1433	3	with	with	IN
cord-022561-rv5j1201	1433	4	type	type	NN
cord-022561-rv5j1201	1433	5	II	II	NNP
cord-022561-rv5j1201	1433	6	BVDV	BVDV	NNP
cord-022561-rv5j1201	1433	7	also	also	RB
cord-022561-rv5j1201	1433	8	have	have	VBP
cord-022561-rv5j1201	1433	9	impaired	impair	VBN
cord-022561-rv5j1201	1433	10	platelet	platelet	NN
cord-022561-rv5j1201	1433	11	function	function	NN
cord-022561-rv5j1201	1433	12	.	.	.
cord-022561-rv5j1201	1434	1	Cattle	Cattle	NNS
cord-022561-rv5j1201	1434	2	with	with	IN
cord-022561-rv5j1201	1434	3	the	the	DT
cord-022561-rv5j1201	1434	4	hemorrhagic	hemorrhagic	JJ
cord-022561-rv5j1201	1434	5	syndrome	syndrome	NN
cord-022561-rv5j1201	1434	6	are	be	VBP
cord-022561-rv5j1201	1434	7	severely	severely	RB
cord-022561-rv5j1201	1434	8	thrombocytopenic	thrombocytopenic	JJ
cord-022561-rv5j1201	1434	9	and	and	CC
cord-022561-rv5j1201	1434	10	neutropenic	neutropenic	JJ
cord-022561-rv5j1201	1434	11	with	with	IN
cord-022561-rv5j1201	1434	12	multisystemic	multisystemic	JJ
cord-022561-rv5j1201	1434	13	hemorrhages	hemorrhage	NNS
cord-022561-rv5j1201	1434	14	,	,	,
cord-022561-rv5j1201	1434	15	particularly	particularly	RB
cord-022561-rv5j1201	1434	16	of	of	IN
cord-022561-rv5j1201	1434	17	the	the	DT
cord-022561-rv5j1201	1434	18	digestive	digestive	JJ
cord-022561-rv5j1201	1434	19	tract	tract	NN
cord-022561-rv5j1201	1434	20	,	,	,
cord-022561-rv5j1201	1434	21	spleen	spleen	NNS
cord-022561-rv5j1201	1434	22	,	,	,
cord-022561-rv5j1201	1434	23	gallbladder	gallbladder	NN
cord-022561-rv5j1201	1434	24	,	,	,
cord-022561-rv5j1201	1434	25	urinary	urinary	JJ
cord-022561-rv5j1201	1434	26	bladder	bladder	NN
cord-022561-rv5j1201	1434	27	,	,	,
cord-022561-rv5j1201	1434	28	and	and	CC
cord-022561-rv5j1201	1434	29	lymph	lymph	NN
cord-022561-rv5j1201	1434	30	nodes	node	NNS
cord-022561-rv5j1201	1434	31	.	.	.
cord-022561-rv5j1201	1435	1	Histologic	Histologic	NNP
cord-022561-rv5j1201	1435	2	lesions	lesion	NNS
cord-022561-rv5j1201	1435	3	include	include	VBP
cord-022561-rv5j1201	1435	4	hemorrhage	hemorrhage	NN
cord-022561-rv5j1201	1435	5	,	,	,
cord-022561-rv5j1201	1435	6	epithelial	epithelial	JJ
cord-022561-rv5j1201	1435	7	necrosis	necrosis	NN
cord-022561-rv5j1201	1435	8	of	of	IN
cord-022561-rv5j1201	1435	9	enterocytes	enterocyte	NNS
cord-022561-rv5j1201	1435	10	,	,	,
cord-022561-rv5j1201	1435	11	intestinal	intestinal	JJ
cord-022561-rv5j1201	1435	12	erosions	erosion	NNS
cord-022561-rv5j1201	1435	13	,	,	,
cord-022561-rv5j1201	1435	14	crypt	crypt	NN
cord-022561-rv5j1201	1435	15	proliferation	proliferation	NN
cord-022561-rv5j1201	1435	16	with	with	IN
cord-022561-rv5j1201	1435	17	microabscesses	microabscesse	NNS
cord-022561-rv5j1201	1435	18	,	,	,
cord-022561-rv5j1201	1435	19	and	and	CC
cord-022561-rv5j1201	1435	20	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	1435	21	depletion	depletion	NN
cord-022561-rv5j1201	1435	22	of	of	IN
cord-022561-rv5j1201	1435	23	the	the	DT
cord-022561-rv5j1201	1435	24	gut	gut	NN
cord-022561-rv5j1201	1435	25	-	-	HYPH
cord-022561-rv5j1201	1435	26	associated	associate	VBN
cord-022561-rv5j1201	1435	27	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	1435	28	tissue	tissue	NN
cord-022561-rv5j1201	1435	29	,	,	,
cord-022561-rv5j1201	1435	30	Peyer	Peyer	NNP
cord-022561-rv5j1201	1435	31	's	's	POS
cord-022561-rv5j1201	1435	32	patches	patch	NNS
cord-022561-rv5j1201	1435	33	,	,	,
cord-022561-rv5j1201	1435	34	and	and	CC
cord-022561-rv5j1201	1435	35	spleen	spleen	NNS
cord-022561-rv5j1201	1435	36	.	.	.
cord-022561-rv5j1201	1436	1	Lesions	lesion	NNS
cord-022561-rv5j1201	1436	2	of	of	IN
cord-022561-rv5j1201	1436	3	the	the	DT
cord-022561-rv5j1201	1436	4	bone	bone	NN
cord-022561-rv5j1201	1436	5	marrow	marrow	NN
cord-022561-rv5j1201	1436	6	are	be	VBP
cord-022561-rv5j1201	1436	7	variable	variable	JJ
cord-022561-rv5j1201	1436	8	,	,	,
cord-022561-rv5j1201	1436	9	as	as	IN
cord-022561-rv5j1201	1436	10	previously	previously	RB
cord-022561-rv5j1201	1436	11	described	describe	VBN
cord-022561-rv5j1201	1436	12	.	.	.
cord-022561-rv5j1201	1437	1	Bovine	bovine	JJ
cord-022561-rv5j1201	1437	2	Neonatal	Neonatal	NNP
cord-022561-rv5j1201	1437	3	Pancytopenia	Pancytopenia	NNP
cord-022561-rv5j1201	1437	4	.	.	.
cord-022561-rv5j1201	1438	1	Bovine	bovine	JJ
cord-022561-rv5j1201	1438	2	neonatal	neonatal	JJ
cord-022561-rv5j1201	1438	3	pancytopenia	pancytopenia	NNS
cord-022561-rv5j1201	1438	4	(	(	-LRB-
cord-022561-rv5j1201	1438	5	BNP	BNP	NNP
cord-022561-rv5j1201	1438	6	)	)	-RRB-
cord-022561-rv5j1201	1438	7	is	be	VBZ
cord-022561-rv5j1201	1438	8	caused	cause	VBN
cord-022561-rv5j1201	1438	9	by	by	IN
cord-022561-rv5j1201	1438	10	alloantibodies	alloantibody	NNS
cord-022561-rv5j1201	1438	11	absorbed	absorb	VBN
cord-022561-rv5j1201	1438	12	from	from	IN
cord-022561-rv5j1201	1438	13	colostrum	colostrum	NN
cord-022561-rv5j1201	1438	14	,	,	,
cord-022561-rv5j1201	1438	15	resulting	result	VBG
cord-022561-rv5j1201	1438	16	in	in	IN
cord-022561-rv5j1201	1438	17	a	a	DT
cord-022561-rv5j1201	1438	18	hemorrhagic	hemorrhagic	JJ
cord-022561-rv5j1201	1438	19	syndrome	syndrome	NN
cord-022561-rv5j1201	1438	20	in	in	IN
cord-022561-rv5j1201	1438	21	calves	calf	NNS
cord-022561-rv5j1201	1438	22	.	.	.
cord-022561-rv5j1201	1439	1	The	the	DT
cord-022561-rv5j1201	1439	2	syndrome	syndrome	NN
cord-022561-rv5j1201	1439	3	was	be	VBD
cord-022561-rv5j1201	1439	4	first	first	RB
cord-022561-rv5j1201	1439	5	recognized	recognize	VBN
cord-022561-rv5j1201	1439	6	in	in	IN
cord-022561-rv5j1201	1439	7	Europe	Europe	NNP
cord-022561-rv5j1201	1439	8	in	in	IN
cord-022561-rv5j1201	1439	9	the	the	DT
cord-022561-rv5j1201	1439	10	early	early	JJ
cord-022561-rv5j1201	1439	11	2000s	2000	NNS
cord-022561-rv5j1201	1439	12	and	and	CC
cord-022561-rv5j1201	1439	13	has	have	VBZ
cord-022561-rv5j1201	1439	14	since	since	IN
cord-022561-rv5j1201	1439	15	been	be	VBN
cord-022561-rv5j1201	1439	16	experimentally	experimentally	RB
cord-022561-rv5j1201	1439	17	correlated	correlate	VBN
cord-022561-rv5j1201	1439	18	with	with	IN
cord-022561-rv5j1201	1439	19	prior	prior	JJ
cord-022561-rv5j1201	1439	20	vaccination	vaccination	NN
cord-022561-rv5j1201	1439	21	of	of	IN
cord-022561-rv5j1201	1439	22	affected	affected	JJ
cord-022561-rv5j1201	1439	23	calves	calf	NNS
cord-022561-rv5j1201	1439	24	'	'	POS
cord-022561-rv5j1201	1439	25	dams	dam	NNS
cord-022561-rv5j1201	1439	26	with	with	IN
cord-022561-rv5j1201	1439	27	a	a	DT
cord-022561-rv5j1201	1439	28	commercial	commercial	JJ
cord-022561-rv5j1201	1439	29	BVDV	BVDV	NNP
cord-022561-rv5j1201	1439	30	vaccine	vaccine	NN
cord-022561-rv5j1201	1439	31	(	(	-LRB-
cord-022561-rv5j1201	1439	32	Pregsure	Pregsure	NNP
cord-022561-rv5j1201	1439	33	BVD	BVD	NNP
cord-022561-rv5j1201	1439	34	;	;	:
cord-022561-rv5j1201	1439	35	Pfizer	Pfizer	NNP
cord-022561-rv5j1201	1439	36	Animal	Animal	NNP
cord-022561-rv5j1201	1439	37	Health	Health	NNP
cord-022561-rv5j1201	1439	38	)	)	-RRB-
cord-022561-rv5j1201	1439	39	.	.	.
cord-022561-rv5j1201	1440	1	The	the	DT
cord-022561-rv5j1201	1440	2	vaccine	vaccine	NN
cord-022561-rv5j1201	1440	3	has	have	VBZ
cord-022561-rv5j1201	1440	4	since	since	IN
cord-022561-rv5j1201	1440	5	been	be	VBN
cord-022561-rv5j1201	1440	6	voluntarily	voluntarily	RB
cord-022561-rv5j1201	1440	7	recalled	recall	VBN
cord-022561-rv5j1201	1440	8	from	from	IN
cord-022561-rv5j1201	1440	9	the	the	DT
cord-022561-rv5j1201	1440	10	market	market	NN
cord-022561-rv5j1201	1440	11	.	.	.
cord-022561-rv5j1201	1441	1	It	-PRON-	PRP
cord-022561-rv5j1201	1441	2	is	be	VBZ
cord-022561-rv5j1201	1441	3	thought	think	VBN
cord-022561-rv5j1201	1441	4	that	that	IN
cord-022561-rv5j1201	1441	5	vaccination	vaccination	NN
cord-022561-rv5j1201	1441	6	induces	induce	VBZ
cord-022561-rv5j1201	1441	7	alloantibody	alloantibody	NN
cord-022561-rv5j1201	1441	8	formation	formation	NN
cord-022561-rv5j1201	1441	9	by	by	IN
cord-022561-rv5j1201	1441	10	the	the	DT
cord-022561-rv5j1201	1441	11	dam	dam	NN
cord-022561-rv5j1201	1441	12	.	.	.
cord-022561-rv5j1201	1442	1	The	the	DT
cord-022561-rv5j1201	1442	2	alloantibodies	alloantibody	NNS
cord-022561-rv5j1201	1442	3	are	be	VBP
cord-022561-rv5j1201	1442	4	ingested	ingest	VBN
cord-022561-rv5j1201	1442	5	by	by	IN
cord-022561-rv5j1201	1442	6	the	the	DT
cord-022561-rv5j1201	1442	7	calf	calf	NN
cord-022561-rv5j1201	1442	8	and	and	CC
cord-022561-rv5j1201	1442	9	bind	bind	VB
cord-022561-rv5j1201	1442	10	to	to	IN
cord-022561-rv5j1201	1442	11	the	the	DT
cord-022561-rv5j1201	1442	12	calf	calf	NN
cord-022561-rv5j1201	1442	13	's	's	POS
cord-022561-rv5j1201	1442	14	hematopoietic	hematopoietic	JJ
cord-022561-rv5j1201	1442	15	progenitor	progenitor	NN
cord-022561-rv5j1201	1442	16	cells	cell	NNS
cord-022561-rv5j1201	1442	17	,	,	,
cord-022561-rv5j1201	1442	18	resulting	result	VBG
cord-022561-rv5j1201	1442	19	in	in	IN
cord-022561-rv5j1201	1442	20	functional	functional	JJ
cord-022561-rv5j1201	1442	21	compromise	compromise	NN
cord-022561-rv5j1201	1442	22	of	of	IN
cord-022561-rv5j1201	1442	23	those	those	DT
cord-022561-rv5j1201	1442	24	cells	cell	NNS
cord-022561-rv5j1201	1442	25	.	.	.
cord-022561-rv5j1201	1443	1	Acutely	acutely	RB
cord-022561-rv5j1201	1443	2	affected	affected	JJ
cord-022561-rv5j1201	1443	3	calves	calf	NNS
cord-022561-rv5j1201	1443	4	are	be	VBP
cord-022561-rv5j1201	1443	5	less	less	JJR
cord-022561-rv5j1201	1443	6	than	than	IN
cord-022561-rv5j1201	1443	7	a	a	DT
cord-022561-rv5j1201	1443	8	year	year	NN
cord-022561-rv5j1201	1443	9	of	of	IN
cord-022561-rv5j1201	1443	10	age	age	NN
cord-022561-rv5j1201	1443	11	and	and	CC
cord-022561-rv5j1201	1443	12	have	have	VBP
cord-022561-rv5j1201	1443	13	peripheral	peripheral	JJ
cord-022561-rv5j1201	1443	14	thrombocytopenia	thrombocytopenia	NNS
cord-022561-rv5j1201	1443	15	and	and	CC
cord-022561-rv5j1201	1443	16	neutropenia	neutropenia	NN
cord-022561-rv5j1201	1443	17	.	.	.
cord-022561-rv5j1201	1444	1	Death	death	NN
cord-022561-rv5j1201	1444	2	results	result	NNS
cord-022561-rv5j1201	1444	3	from	from	IN
cord-022561-rv5j1201	1444	4	thrombocytopenia	thrombocytopenia	NN
cord-022561-rv5j1201	1444	5	-	-	HYPH
cord-022561-rv5j1201	1444	6	induced	induce	VBN
cord-022561-rv5j1201	1444	7	hemorrhages	hemorrhage	NNS
cord-022561-rv5j1201	1444	8	or	or	CC
cord-022561-rv5j1201	1444	9	neutropenia	neutropenia	NN
cord-022561-rv5j1201	1444	10	-	-	HYPH
cord-022561-rv5j1201	1444	11	induced	induce	VBN
cord-022561-rv5j1201	1444	12	secondary	secondary	JJ
cord-022561-rv5j1201	1444	13	infections	infection	NNS
cord-022561-rv5j1201	1444	14	,	,	,
cord-022561-rv5j1201	1444	15	including	include	VBG
cord-022561-rv5j1201	1444	16	pneumonia	pneumonia	NN
cord-022561-rv5j1201	1444	17	,	,	,
cord-022561-rv5j1201	1444	18	enteritis	enteritis	NN
cord-022561-rv5j1201	1444	19	,	,	,
cord-022561-rv5j1201	1444	20	and	and	CC
cord-022561-rv5j1201	1444	21	septicemia	septicemia	NN
cord-022561-rv5j1201	1444	22	.	.	.
cord-022561-rv5j1201	1445	1	Within	within	IN
cord-022561-rv5j1201	1445	2	the	the	DT
cord-022561-rv5j1201	1445	3	bone	bone	NN
cord-022561-rv5j1201	1445	4	marrow	marrow	NN
cord-022561-rv5j1201	1445	5	there	there	EX
cord-022561-rv5j1201	1445	6	is	be	VBZ
cord-022561-rv5j1201	1445	7	erythroid	erythroid	JJ
cord-022561-rv5j1201	1445	8	,	,	,
cord-022561-rv5j1201	1445	9	myeloid	myeloid	NN
cord-022561-rv5j1201	1445	10	,	,	,
cord-022561-rv5j1201	1445	11	and	and	CC
cord-022561-rv5j1201	1445	12	megakaryocytic	megakaryocytic	JJ
cord-022561-rv5j1201	1445	13	hypoplasia	hypoplasia	NN
cord-022561-rv5j1201	1445	14	.	.	.
cord-022561-rv5j1201	1446	1	Cyclic	Cyclic	NNP
cord-022561-rv5j1201	1446	2	Hematopoiesis	Hematopoiesis	NNP
cord-022561-rv5j1201	1446	3	.	.	.
cord-022561-rv5j1201	1447	1	Cyclic	cyclic	JJ
cord-022561-rv5j1201	1447	2	hematopoiesis	hematopoiesis	NN
cord-022561-rv5j1201	1447	3	(	(	-LRB-
cord-022561-rv5j1201	1447	4	also	also	RB
cord-022561-rv5j1201	1447	5	known	know	VBN
cord-022561-rv5j1201	1447	6	as	as	IN
cord-022561-rv5j1201	1447	7	lethal	lethal	JJ
cord-022561-rv5j1201	1447	8	gray	gray	JJ
cord-022561-rv5j1201	1447	9	collie	collie	NN
cord-022561-rv5j1201	1447	10	disease	disease	NN
cord-022561-rv5j1201	1447	11	)	)	-RRB-
cord-022561-rv5j1201	1447	12	is	be	VBZ
cord-022561-rv5j1201	1447	13	an	an	DT
cord-022561-rv5j1201	1447	14	autosomal	autosomal	JJ
cord-022561-rv5j1201	1447	15	recessive	recessive	JJ
cord-022561-rv5j1201	1447	16	disorder	disorder	NN
cord-022561-rv5j1201	1447	17	of	of	IN
cord-022561-rv5j1201	1447	18	pluripotent	pluripotent	JJ
cord-022561-rv5j1201	1447	19	HSCs	hscs	NN
cord-022561-rv5j1201	1447	20	in	in	IN
cord-022561-rv5j1201	1447	21	gray	gray	JJ
cord-022561-rv5j1201	1447	22	collie	collie	NN
cord-022561-rv5j1201	1447	23	dogs	dog	NNS
cord-022561-rv5j1201	1447	24	.	.	.
cord-022561-rv5j1201	1448	1	A	a	DT
cord-022561-rv5j1201	1448	2	defect	defect	NN
cord-022561-rv5j1201	1448	3	in	in	IN
cord-022561-rv5j1201	1448	4	the	the	DT
cord-022561-rv5j1201	1448	5	adaptor	adaptor	NN
cord-022561-rv5j1201	1448	6	protein	protein	NN
cord-022561-rv5j1201	1448	7	complex	complex	NN
cord-022561-rv5j1201	1448	8	(	(	-LRB-
cord-022561-rv5j1201	1448	9	AP3	AP3	NNP
cord-022561-rv5j1201	1448	10	)	)	-RRB-
cord-022561-rv5j1201	1448	11	results	result	NNS
cord-022561-rv5j1201	1448	12	in	in	IN
cord-022561-rv5j1201	1448	13	defective	defective	JJ
cord-022561-rv5j1201	1448	14	intracellular	intracellular	JJ
cord-022561-rv5j1201	1448	15	signaling	signaling	NN
cord-022561-rv5j1201	1448	16	and	and	CC
cord-022561-rv5j1201	1448	17	predictable	predictable	JJ
cord-022561-rv5j1201	1448	18	fluctuations	fluctuation	NNS
cord-022561-rv5j1201	1448	19	in	in	IN
cord-022561-rv5j1201	1448	20	concentrations	concentration	NNS
cord-022561-rv5j1201	1448	21	of	of	IN
cord-022561-rv5j1201	1448	22	blood	blood	NN
cord-022561-rv5j1201	1448	23	cells	cell	NNS
cord-022561-rv5j1201	1448	24	that	that	WDT
cord-022561-rv5j1201	1448	25	occur	occur	VBP
cord-022561-rv5j1201	1448	26	in	in	IN
cord-022561-rv5j1201	1448	27	14-day	14-day	CD
cord-022561-rv5j1201	1448	28	cycles	cycle	NNS
cord-022561-rv5j1201	1448	29	.	.	.
cord-022561-rv5j1201	1449	1	The	the	DT
cord-022561-rv5j1201	1449	2	pattern	pattern	NN
cord-022561-rv5j1201	1449	3	is	be	VBZ
cord-022561-rv5j1201	1449	4	cyclic	cyclic	JJ
cord-022561-rv5j1201	1449	5	marked	marked	JJ
cord-022561-rv5j1201	1449	6	neutropenia	neutropenia	NN
cord-022561-rv5j1201	1449	7	,	,	,
cord-022561-rv5j1201	1449	8	and	and	CC
cord-022561-rv5j1201	1449	9	in	in	IN
cord-022561-rv5j1201	1449	10	a	a	DT
cord-022561-rv5j1201	1449	11	different	different	JJ
cord-022561-rv5j1201	1449	12	phase	phase	NN
cord-022561-rv5j1201	1449	13	,	,	,
cord-022561-rv5j1201	1449	14	cyclic	cyclic	JJ
cord-022561-rv5j1201	1449	15	reticulocytosis	reticulocytosis	NN
cord-022561-rv5j1201	1449	16	,	,	,
cord-022561-rv5j1201	1449	17	monocytosis	monocytosis	NNP
cord-022561-rv5j1201	1449	18	,	,	,
cord-022561-rv5j1201	1449	19	and	and	CC
cord-022561-rv5j1201	1449	20	thrombocytosis	thrombocytosis	NNP
cord-022561-rv5j1201	1449	21	.	.	.
cord-022561-rv5j1201	1450	1	Production	production	NN
cord-022561-rv5j1201	1450	2	of	of	IN
cord-022561-rv5j1201	1450	3	key	key	JJ
cord-022561-rv5j1201	1450	4	cytokines	cytokine	NNS
cord-022561-rv5j1201	1450	5	involved	involve	VBN
cord-022561-rv5j1201	1450	6	in	in	IN
cord-022561-rv5j1201	1450	7	regulation	regulation	NN
cord-022561-rv5j1201	1450	8	of	of	IN
cord-022561-rv5j1201	1450	9	hematopoiesis	hematopoiesis	NN
cord-022561-rv5j1201	1450	10	is	be	VBZ
cord-022561-rv5j1201	1450	11	also	also	RB
cord-022561-rv5j1201	1450	12	cyclic	cyclic	JJ
cord-022561-rv5j1201	1450	13	.	.	.
cord-022561-rv5j1201	1451	1	Neutropenia	neutropenia	NN
cord-022561-rv5j1201	1451	2	predisposes	predispose	VBZ
cord-022561-rv5j1201	1451	3	affected	affect	VBN
cord-022561-rv5j1201	1451	4	animals	animal	NNS
cord-022561-rv5j1201	1451	5	to	to	IN
cord-022561-rv5j1201	1451	6	infection	infection	NN
cord-022561-rv5j1201	1451	7	,	,	,
cord-022561-rv5j1201	1451	8	and	and	CC
cord-022561-rv5j1201	1451	9	many	many	JJ
cord-022561-rv5j1201	1451	10	die	die	VBP
cord-022561-rv5j1201	1451	11	of	of	IN
cord-022561-rv5j1201	1451	12	infectious	infectious	JJ
cord-022561-rv5j1201	1451	13	causes	cause	NNS
cord-022561-rv5j1201	1451	14	.	.	.
cord-022561-rv5j1201	1452	1	Affected	affected	JJ
cord-022561-rv5j1201	1452	2	animals	animal	NNS
cord-022561-rv5j1201	1452	3	have	have	VBP
cord-022561-rv5j1201	1452	4	dilute	dilute	VB
cord-022561-rv5j1201	1452	5	hair	hair	NN
cord-022561-rv5j1201	1452	6	coats	coat	NNS
cord-022561-rv5j1201	1452	7	and	and	CC
cord-022561-rv5j1201	1452	8	lesions	lesion	NNS
cord-022561-rv5j1201	1452	9	with	with	IN
cord-022561-rv5j1201	1452	10	acute	acute	JJ
cord-022561-rv5j1201	1452	11	or	or	CC
cord-022561-rv5j1201	1452	12	chronic	chronic	JJ
cord-022561-rv5j1201	1452	13	infectious	infectious	JJ
cord-022561-rv5j1201	1452	14	disease	disease	NN
cord-022561-rv5j1201	1452	15	,	,	,
cord-022561-rv5j1201	1452	16	especially	especially	RB
cord-022561-rv5j1201	1452	17	of	of	IN
cord-022561-rv5j1201	1452	18	the	the	DT
cord-022561-rv5j1201	1452	19	lungs	lung	NNS
cord-022561-rv5j1201	1452	20	,	,	,
cord-022561-rv5j1201	1452	21	gastrointestinal	gastrointestinal	JJ
cord-022561-rv5j1201	1452	22	tract	tract	NN
cord-022561-rv5j1201	1452	23	,	,	,
cord-022561-rv5j1201	1452	24	and	and	CC
cord-022561-rv5j1201	1452	25	kidneys	kidney	NNS
cord-022561-rv5j1201	1452	26	.	.	.
cord-022561-rv5j1201	1453	1	Dogs	dog	NNS
cord-022561-rv5j1201	1453	2	older	old	JJR
cord-022561-rv5j1201	1453	3	than	than	IN
cord-022561-rv5j1201	1453	4	30	30	CD
cord-022561-rv5j1201	1453	5	weeks	week	NNS
cord-022561-rv5j1201	1453	6	of	of	IN
cord-022561-rv5j1201	1453	7	age	age	NN
cord-022561-rv5j1201	1453	8	have	have	VBP
cord-022561-rv5j1201	1453	9	systemic	systemic	JJ
cord-022561-rv5j1201	1453	10	amyloidosis	amyloidosis	NN
cord-022561-rv5j1201	1453	11	,	,	,
cord-022561-rv5j1201	1453	12	which	which	WDT
cord-022561-rv5j1201	1453	13	occurs	occur	VBZ
cord-022561-rv5j1201	1453	14	because	because	IN
cord-022561-rv5j1201	1453	15	of	of	IN
cord-022561-rv5j1201	1453	16	cyclic	cyclic	JJ
cord-022561-rv5j1201	1453	17	increases	increase	NNS
cord-022561-rv5j1201	1453	18	in	in	IN
cord-022561-rv5j1201	1453	19	concentration	concentration	NN
cord-022561-rv5j1201	1453	20	of	of	IN
cord-022561-rv5j1201	1453	21	acute	acute	JJ
cord-022561-rv5j1201	1453	22	phase	phase	NN
cord-022561-rv5j1201	1453	23	proteins	protein	NNS
cord-022561-rv5j1201	1453	24	during	during	IN
cord-022561-rv5j1201	1453	25	phases	phase	NNS
cord-022561-rv5j1201	1453	26	of	of	IN
cord-022561-rv5j1201	1453	27	monocytosis	monocytosis	NNP
cord-022561-rv5j1201	1453	28	.	.	.
cord-022561-rv5j1201	1454	1	Phosphofructokinase	Phosphofructokinase	NNP
cord-022561-rv5j1201	1454	2	Deficiency	deficiency	NN
cord-022561-rv5j1201	1454	3	.	.	.
cord-022561-rv5j1201	1455	1	Inherited	inherit	VBN
cord-022561-rv5j1201	1455	2	autosomal	autosomal	JJ
cord-022561-rv5j1201	1455	3	recessive	recessive	JJ
cord-022561-rv5j1201	1455	4	deficiency	deficiency	NN
cord-022561-rv5j1201	1455	5	of	of	IN
cord-022561-rv5j1201	1455	6	the	the	DT
cord-022561-rv5j1201	1455	7	erythrocyte	erythrocyte	NN
cord-022561-rv5j1201	1455	8	glycolytic	glycolytic	JJ
cord-022561-rv5j1201	1455	9	enzyme	enzyme	NN
cord-022561-rv5j1201	1455	10	,	,	,
cord-022561-rv5j1201	1455	11	phosphofructokinase	phosphofructokinase	NNP
cord-022561-rv5j1201	1455	12	(	(	-LRB-
cord-022561-rv5j1201	1455	13	PFK	PFK	NNP
cord-022561-rv5j1201	1455	14	)	)	-RRB-
cord-022561-rv5j1201	1455	15	,	,	,
cord-022561-rv5j1201	1455	16	is	be	VBZ
cord-022561-rv5j1201	1455	17	described	describe	VBN
cord-022561-rv5j1201	1455	18	in	in	IN
cord-022561-rv5j1201	1455	19	English	English	NNP
cord-022561-rv5j1201	1455	20	springer	springer	NNP
cord-022561-rv5j1201	1455	21	spaniel	spaniel	NN
cord-022561-rv5j1201	1455	22	,	,	,
cord-022561-rv5j1201	1455	23	American	american	JJ
cord-022561-rv5j1201	1455	24	cocker	cocker	NN
cord-022561-rv5j1201	1455	25	spaniel	spaniel	NN
cord-022561-rv5j1201	1455	26	,	,	,
cord-022561-rv5j1201	1455	27	and	and	CC
cord-022561-rv5j1201	1455	28	mixed	mix	VBN
cord-022561-rv5j1201	1455	29	-	-	HYPH
cord-022561-rv5j1201	1455	30	breed	breed	NN
cord-022561-rv5j1201	1455	31	dogs	dog	NNS
cord-022561-rv5j1201	1455	32	.	.	.
cord-022561-rv5j1201	1456	1	There	there	EX
cord-022561-rv5j1201	1456	2	are	be	VBP
cord-022561-rv5j1201	1456	3	three	three	CD
cord-022561-rv5j1201	1456	4	genes	gene	NNS
cord-022561-rv5j1201	1456	5	encoding	encode	VBG
cord-022561-rv5j1201	1456	6	PFK	PFK	NNP
cord-022561-rv5j1201	1456	7	enzymes	enzyme	NNS
cord-022561-rv5j1201	1456	8	,	,	,
cord-022561-rv5j1201	1456	9	designated	designate	VBN
cord-022561-rv5j1201	1456	10	M	M	NNP
cord-022561-rv5j1201	1456	11	-	-	HYPH
cord-022561-rv5j1201	1456	12	PFK	PFK	NNP
cord-022561-rv5j1201	1456	13	in	in	IN
cord-022561-rv5j1201	1456	14	muscle	muscle	NN
cord-022561-rv5j1201	1456	15	and	and	CC
cord-022561-rv5j1201	1456	16	erythrocytes	erythrocyte	NNS
cord-022561-rv5j1201	1456	17	,	,	,
cord-022561-rv5j1201	1456	18	L	l	NN
cord-022561-rv5j1201	1456	19	-	-	HYPH
cord-022561-rv5j1201	1456	20	PFK	PFK	NNP
cord-022561-rv5j1201	1456	21	in	in	IN
cord-022561-rv5j1201	1456	22	liver	liver	NN
cord-022561-rv5j1201	1456	23	,	,	,
cord-022561-rv5j1201	1456	24	and	and	CC
cord-022561-rv5j1201	1456	25	P	p	NN
cord-022561-rv5j1201	1456	26	-	-	HYPH
cord-022561-rv5j1201	1456	27	PFK	PFK	NNP
cord-022561-rv5j1201	1456	28	in	in	IN
cord-022561-rv5j1201	1456	29	platelets	platelet	NNS
cord-022561-rv5j1201	1456	30	.	.	.
cord-022561-rv5j1201	1457	1	A	a	DT
cord-022561-rv5j1201	1457	2	point	point	NN
cord-022561-rv5j1201	1457	3	mutation	mutation	NN
cord-022561-rv5j1201	1457	4	in	in	IN
cord-022561-rv5j1201	1457	5	the	the	DT
cord-022561-rv5j1201	1457	6	gene	gene	NN
cord-022561-rv5j1201	1457	7	coding	coding	NN
cord-022561-rv5j1201	1457	8	for	for	IN
cord-022561-rv5j1201	1457	9	M	M	NNP
cord-022561-rv5j1201	1457	10	-	-	HYPH
cord-022561-rv5j1201	1457	11	PFK	PFK	NNP
cord-022561-rv5j1201	1457	12	results	result	NNS
cord-022561-rv5j1201	1457	13	in	in	IN
cord-022561-rv5j1201	1457	14	an	an	DT
cord-022561-rv5j1201	1457	15	unstable	unstable	JJ
cord-022561-rv5j1201	1457	16	,	,	,
cord-022561-rv5j1201	1457	17	truncated	truncated	JJ
cord-022561-rv5j1201	1457	18	molecule	molecule	NN
cord-022561-rv5j1201	1457	19	.	.	.
cord-022561-rv5j1201	1458	1	Erythrocytes	erythrocyte	NNS
cord-022561-rv5j1201	1458	2	in	in	IN
cord-022561-rv5j1201	1458	3	PFK	PFK	NNP
cord-022561-rv5j1201	1458	4	-	-	HYPH
cord-022561-rv5j1201	1458	5	deficient	deficient	JJ
cord-022561-rv5j1201	1458	6	dogs	dog	NNS
cord-022561-rv5j1201	1458	7	have	have	VBP
cord-022561-rv5j1201	1458	8	decreased	decrease	VBN
cord-022561-rv5j1201	1458	9	ATP	ATP	NNP
cord-022561-rv5j1201	1458	10	and	and	CC
cord-022561-rv5j1201	1458	11	2,3-diphosphoglycerate	2,3-diphosphoglycerate	CD
cord-022561-rv5j1201	1458	12	(	(	-LRB-
cord-022561-rv5j1201	1458	13	2,3-DPG	2,3-dpg	CD
cord-022561-rv5j1201	1458	14	)	)	-RRB-
cord-022561-rv5j1201	1458	15	production	production	NN
cord-022561-rv5j1201	1458	16	and	and	CC
cord-022561-rv5j1201	1458	17	increased	increase	VBN
cord-022561-rv5j1201	1458	18	fragility	fragility	NN
cord-022561-rv5j1201	1458	19	under	under	IN
cord-022561-rv5j1201	1458	20	alkaline	alkaline	JJ
cord-022561-rv5j1201	1458	21	conditions	condition	NNS
cord-022561-rv5j1201	1458	22	.	.	.
cord-022561-rv5j1201	1459	1	The	the	DT
cord-022561-rv5j1201	1459	2	disease	disease	NN
cord-022561-rv5j1201	1459	3	is	be	VBZ
cord-022561-rv5j1201	1459	4	characterized	characterize	VBN
cord-022561-rv5j1201	1459	5	by	by	IN
cord-022561-rv5j1201	1459	6	chronic	chronic	JJ
cord-022561-rv5j1201	1459	7	hemolysis	hemolysis	NN
cord-022561-rv5j1201	1459	8	with	with	IN
cord-022561-rv5j1201	1459	9	marked	marked	JJ
cord-022561-rv5j1201	1459	10	reticulocytosis	reticulocytosis	NN
cord-022561-rv5j1201	1459	11	.	.	.
cord-022561-rv5j1201	1460	1	The	the	DT
cord-022561-rv5j1201	1460	2	marked	marked	JJ
cord-022561-rv5j1201	1460	3	regenerative	regenerative	JJ
cord-022561-rv5j1201	1460	4	response	response	NN
cord-022561-rv5j1201	1460	5	may	may	MD
cord-022561-rv5j1201	1460	6	compensate	compensate	VB
cord-022561-rv5j1201	1460	7	for	for	IN
cord-022561-rv5j1201	1460	8	the	the	DT
cord-022561-rv5j1201	1460	9	ongoing	ongoing	JJ
cord-022561-rv5j1201	1460	10	hemolysis	hemolysis	NN
cord-022561-rv5j1201	1460	11	;	;	:
cord-022561-rv5j1201	1460	12	therefore	therefore	RB
cord-022561-rv5j1201	1460	13	Erythrophagocytosis	Erythrophagocytosis	NNP
cord-022561-rv5j1201	1460	14	,	,	,
cord-022561-rv5j1201	1460	15	thrombosis	thrombosis	NN
cord-022561-rv5j1201	1460	16	,	,	,
cord-022561-rv5j1201	1460	17	and	and	CC
cord-022561-rv5j1201	1460	18	histologic	histologic	JJ
cord-022561-rv5j1201	1460	19	changes	change	NNS
cord-022561-rv5j1201	1460	20	of	of	IN
cord-022561-rv5j1201	1460	21	ischemia	ischemia	NN
cord-022561-rv5j1201	1460	22	are	be	VBP
cord-022561-rv5j1201	1460	23	common	common	JJ
cord-022561-rv5j1201	1460	24	,	,	,
cord-022561-rv5j1201	1460	25	especially	especially	RB
cord-022561-rv5j1201	1460	26	within	within	IN
cord-022561-rv5j1201	1460	27	the	the	DT
cord-022561-rv5j1201	1460	28	spleen	spleen	NN
cord-022561-rv5j1201	1460	29	,	,	,
cord-022561-rv5j1201	1460	30	liver	liver	NN
cord-022561-rv5j1201	1460	31	,	,	,
cord-022561-rv5j1201	1460	32	and	and	CC
cord-022561-rv5j1201	1460	33	lungs	lung	NNS
cord-022561-rv5j1201	1460	34	.	.	.
cord-022561-rv5j1201	1461	1	Affected	affected	JJ
cord-022561-rv5j1201	1461	2	cats	cat	NNS
cord-022561-rv5j1201	1461	3	typically	typically	RB
cord-022561-rv5j1201	1461	4	become	become	VBP
cord-022561-rv5j1201	1461	5	acutely	acutely	RB
cord-022561-rv5j1201	1461	6	ill	ill	JJ
cord-022561-rv5j1201	1461	7	with	with	IN
cord-022561-rv5j1201	1461	8	fever	fever	NN
cord-022561-rv5j1201	1461	9	,	,	,
cord-022561-rv5j1201	1461	10	pallor	pallor	NN
cord-022561-rv5j1201	1461	11	,	,	,
cord-022561-rv5j1201	1461	12	and	and	CC
cord-022561-rv5j1201	1461	13	icterus	icterus	NN
cord-022561-rv5j1201	1461	14	and	and	CC
cord-022561-rv5j1201	1461	15	usually	usually	RB
cord-022561-rv5j1201	1461	16	die	die	VBP
cord-022561-rv5j1201	1461	17	within	within	IN
cord-022561-rv5j1201	1461	18	2	2	CD
cord-022561-rv5j1201	1461	19	to	to	TO
cord-022561-rv5j1201	1461	20	3	3	CD
cord-022561-rv5j1201	1461	21	days	day	NNS
cord-022561-rv5j1201	1461	22	.	.	.
cord-022561-rv5j1201	1462	1	For	for	IN
cord-022561-rv5j1201	1462	2	many	many	JJ
cord-022561-rv5j1201	1462	3	years	year	NNS
cord-022561-rv5j1201	1462	4	,	,	,
cord-022561-rv5j1201	1462	5	cytauxzoonosis	cytauxzoonosis	NNP
cord-022561-rv5j1201	1462	6	was	be	VBD
cord-022561-rv5j1201	1462	7	considered	consider	VBN
cord-022561-rv5j1201	1462	8	to	to	TO
cord-022561-rv5j1201	1462	9	be	be	VB
cord-022561-rv5j1201	1462	10	almost	almost	RB
cord-022561-rv5j1201	1462	11	always	always	RB
cord-022561-rv5j1201	1462	12	fatal	fatal	JJ
cord-022561-rv5j1201	1462	13	.	.	.
cord-022561-rv5j1201	1463	1	However	however	RB
cord-022561-rv5j1201	1463	2	,	,	,
cord-022561-rv5j1201	1463	3	a	a	DT
cord-022561-rv5j1201	1463	4	recent	recent	JJ
cord-022561-rv5j1201	1463	5	not	not	RB
cord-022561-rv5j1201	1463	6	been	be	VBN
cord-022561-rv5j1201	1463	7	identified	identify	VBN
cord-022561-rv5j1201	1463	8	,	,	,
cord-022561-rv5j1201	1463	9	but	but	CC
cord-022561-rv5j1201	1463	10	PK	PK	NNP
cord-022561-rv5j1201	1463	11	deficiency	deficiency	NN
cord-022561-rv5j1201	1463	12	(	(	-LRB-
cord-022561-rv5j1201	1463	13	which	which	WDT
cord-022561-rv5j1201	1463	14	has	have	VBZ
cord-022561-rv5j1201	1463	15	been	be	VBN
cord-022561-rv5j1201	1463	16	reported	report	VBN
cord-022561-rv5j1201	1463	17	in	in	IN
cord-022561-rv5j1201	1463	18	these	these	DT
cord-022561-rv5j1201	1463	19	breeds	breed	NNS
cord-022561-rv5j1201	1463	20	)	)	-RRB-
cord-022561-rv5j1201	1463	21	was	be	VBD
cord-022561-rv5j1201	1463	22	excluded	exclude	VBN
cord-022561-rv5j1201	1463	23	as	as	IN
cord-022561-rv5j1201	1463	24	the	the	DT
cord-022561-rv5j1201	1463	25	cause	cause	NN
cord-022561-rv5j1201	1463	26	.	.	.
cord-022561-rv5j1201	1464	1	Affected	affected	JJ
cord-022561-rv5j1201	1464	2	cats	cat	NNS
cord-022561-rv5j1201	1464	3	have	have	VBP
cord-022561-rv5j1201	1464	4	chronic	chronic	JJ
cord-022561-rv5j1201	1464	5	intermittent	intermittent	JJ
cord-022561-rv5j1201	1464	6	severe	severe	JJ
cord-022561-rv5j1201	1464	7	hemolytic	hemolytic	JJ
cord-022561-rv5j1201	1464	8	anemia	anemia	NN
cord-022561-rv5j1201	1464	9	and	and	CC
cord-022561-rv5j1201	1464	10	often	often	RB
cord-022561-rv5j1201	1464	11	have	have	VBP
cord-022561-rv5j1201	1464	12	other	other	JJ
cord-022561-rv5j1201	1464	13	lesions	lesion	NNS
cord-022561-rv5j1201	1464	14	secondary	secondary	JJ
cord-022561-rv5j1201	1464	15	to	to	IN
cord-022561-rv5j1201	1464	16	hemolytic	hemolytic	JJ
cord-022561-rv5j1201	1464	17	anemia	anemia	NN
cord-022561-rv5j1201	1464	18	(	(	-LRB-
cord-022561-rv5j1201	1464	19	e.g.	e.g.	RB
cord-022561-rv5j1201	1464	20	,	,	,
cord-022561-rv5j1201	1464	21	splenomegaly	splenomegaly	NN
cord-022561-rv5j1201	1464	22	and	and	CC
cord-022561-rv5j1201	1464	23	hyperbilirubinemia	hyperbilirubinemia	NN
cord-022561-rv5j1201	1464	24	)	)	-RRB-
cord-022561-rv5j1201	1464	25	.	.	.
cord-022561-rv5j1201	1465	1	Cytauxzoonosis	Cytauxzoonosis	NNP
cord-022561-rv5j1201	1465	2	.	.	.
cord-022561-rv5j1201	1466	1	Cytauxzoonosis	Cytauxzoonosis	NNP
cord-022561-rv5j1201	1466	2	is	be	VBZ
cord-022561-rv5j1201	1466	3	a	a	DT
cord-022561-rv5j1201	1466	4	severe	severe	JJ
cord-022561-rv5j1201	1466	5	,	,	,
cord-022561-rv5j1201	1466	6	often	often	RB
cord-022561-rv5j1201	1466	7	fatal	fatal	JJ
cord-022561-rv5j1201	1466	8	disease	disease	NN
cord-022561-rv5j1201	1466	9	of	of	IN
cord-022561-rv5j1201	1466	10	domestic	domestic	JJ
cord-022561-rv5j1201	1466	11	cats	cat	NNS
cord-022561-rv5j1201	1466	12	caused	cause	VBN
cord-022561-rv5j1201	1466	13	by	by	IN
cord-022561-rv5j1201	1466	14	the	the	DT
cord-022561-rv5j1201	1466	15	protozoal	protozoal	JJ
cord-022561-rv5j1201	1466	16	organism	organism	NN
cord-022561-rv5j1201	1466	17	,	,	,
cord-022561-rv5j1201	1466	18	Cytauxzoon	Cytauxzoon	NNP
cord-022561-rv5j1201	1466	19	felis	felis	NN
cord-022561-rv5j1201	1466	20	.	.	.
cord-022561-rv5j1201	1467	1	Disease	Disease	NNP
cord-022561-rv5j1201	1467	2	is	be	VBZ
cord-022561-rv5j1201	1467	3	relatively	relatively	RB
cord-022561-rv5j1201	1467	4	common	common	JJ
cord-022561-rv5j1201	1467	5	in	in	IN
cord-022561-rv5j1201	1467	6	the	the	DT
cord-022561-rv5j1201	1467	7	south	south	JJ
cord-022561-rv5j1201	1467	8	central	central	JJ
cord-022561-rv5j1201	1467	9	United	United	NNP
cord-022561-rv5j1201	1467	10	States	States	NNP
cord-022561-rv5j1201	1467	11	,	,	,
cord-022561-rv5j1201	1467	12	particularly	particularly	RB
cord-022561-rv5j1201	1467	13	during	during	IN
cord-022561-rv5j1201	1467	14	summer	summer	NN
cord-022561-rv5j1201	1467	15	months	month	NNS
cord-022561-rv5j1201	1467	16	.	.	.
cord-022561-rv5j1201	1468	1	Bobcats	Bobcats	NNP
cord-022561-rv5j1201	1468	2	(	(	-LRB-
cord-022561-rv5j1201	1468	3	Lynx	Lynx	NNP
cord-022561-rv5j1201	1468	4	rufus	rufus	NNP
cord-022561-rv5j1201	1468	5	)	)	-RRB-
cord-022561-rv5j1201	1468	6	and	and	CC
cord-022561-rv5j1201	1468	7	other	other	JJ
cord-022561-rv5j1201	1468	8	wild	wild	JJ
cord-022561-rv5j1201	1468	9	felids	felid	NNS
cord-022561-rv5j1201	1468	10	are	be	VBP
cord-022561-rv5j1201	1468	11	thought	think	VBN
cord-022561-rv5j1201	1468	12	to	to	TO
cord-022561-rv5j1201	1468	13	be	be	VB
cord-022561-rv5j1201	1468	14	wildlife	wildlife	NN
cord-022561-rv5j1201	1468	15	reservoirs	reservoir	NNS
cord-022561-rv5j1201	1468	16	of	of	IN
cord-022561-rv5j1201	1468	17	disease	disease	NN
cord-022561-rv5j1201	1468	18	.	.	.
cord-022561-rv5j1201	1469	1	C.	C.	NNP
cord-022561-rv5j1201	1469	2	felis	felis	NNP
cord-022561-rv5j1201	1469	3	is	be	VBZ
cord-022561-rv5j1201	1469	4	transmitted	transmit	VBN
cord-022561-rv5j1201	1469	5	by	by	IN
cord-022561-rv5j1201	1469	6	a	a	DT
cord-022561-rv5j1201	1469	7	tick	tick	NN
cord-022561-rv5j1201	1469	8	vector	vector	NN
cord-022561-rv5j1201	1469	9	,	,	,
cord-022561-rv5j1201	1469	10	Dermacentor	Dermacentor	NNP
cord-022561-rv5j1201	1469	11	variabilis	variabilis	NNP
cord-022561-rv5j1201	1469	12	,	,	,
cord-022561-rv5j1201	1469	13	which	which	WDT
cord-022561-rv5j1201	1469	14	is	be	VBZ
cord-022561-rv5j1201	1469	15	probably	probably	RB
cord-022561-rv5j1201	1469	16	essential	essential	JJ
cord-022561-rv5j1201	1469	17	for	for	IN
cord-022561-rv5j1201	1469	18	infectivity	infectivity	NN
cord-022561-rv5j1201	1469	19	of	of	IN
cord-022561-rv5j1201	1469	20	the	the	DT
cord-022561-rv5j1201	1469	21	organism	organism	NN
cord-022561-rv5j1201	1469	22	.	.	.
cord-022561-rv5j1201	1470	1	Cytauxzoonosis	Cytauxzoonosis	NNP
cord-022561-rv5j1201	1470	2	has	have	VBZ
cord-022561-rv5j1201	1470	3	a	a	DT
cord-022561-rv5j1201	1470	4	schizogenous	schizogenous	JJ
cord-022561-rv5j1201	1470	5	phase	phase	NN
cord-022561-rv5j1201	1470	6	within	within	IN
cord-022561-rv5j1201	1470	7	macrophages	macrophage	NNS
cord-022561-rv5j1201	1470	8	throughout	throughout	IN
cord-022561-rv5j1201	1470	9	the	the	DT
cord-022561-rv5j1201	1470	10	body	body	NN
cord-022561-rv5j1201	1470	11	(	(	-LRB-
cord-022561-rv5j1201	1470	12	especially	especially	RB
cord-022561-rv5j1201	1470	13	liver	liver	NN
cord-022561-rv5j1201	1470	14	,	,	,
cord-022561-rv5j1201	1470	15	spleen	spleen	NNS
cord-022561-rv5j1201	1470	16	,	,	,
cord-022561-rv5j1201	1470	17	lung	lung	NN
cord-022561-rv5j1201	1470	18	,	,	,
cord-022561-rv5j1201	1470	19	lymph	lymph	NN
cord-022561-rv5j1201	1470	20	nodes	node	NNS
cord-022561-rv5j1201	1470	21	,	,	,
cord-022561-rv5j1201	1470	22	and	and	CC
cord-022561-rv5j1201	1470	23	bone	bone	NN
cord-022561-rv5j1201	1470	24	marrow	marrow	NN
cord-022561-rv5j1201	1470	25	)	)	-RRB-
cord-022561-rv5j1201	1470	26	that	that	WDT
cord-022561-rv5j1201	1470	27	causes	cause	VBZ
cord-022561-rv5j1201	1470	28	systemic	systemic	JJ
cord-022561-rv5j1201	1470	29	illness	illness	NN
cord-022561-rv5j1201	1470	30	.	.	.
cord-022561-rv5j1201	1471	1	These	these	DT
cord-022561-rv5j1201	1471	2	schizontcontaining	schizontcontaine	VBG
cord-022561-rv5j1201	1471	3	macrophages	macrophage	NNS
cord-022561-rv5j1201	1471	4	enlarge	enlarge	VBP
cord-022561-rv5j1201	1471	5	and	and	CC
cord-022561-rv5j1201	1471	6	accumulate	accumulate	VBP
cord-022561-rv5j1201	1471	7	within	within	IN
cord-022561-rv5j1201	1471	8	the	the	DT
cord-022561-rv5j1201	1471	9	walls	wall	NNS
cord-022561-rv5j1201	1471	10	of	of	IN
cord-022561-rv5j1201	1471	11	veins	vein	NNS
cord-022561-rv5j1201	1471	12	,	,	,
cord-022561-rv5j1201	1471	13	eventually	eventually	RB
cord-022561-rv5j1201	1471	14	causing	cause	VBG
cord-022561-rv5j1201	1471	15	vessel	vessel	NN
cord-022561-rv5j1201	1471	16	occlusion	occlusion	NN
cord-022561-rv5j1201	1471	17	,	,	,
cord-022561-rv5j1201	1471	18	circulatory	circulatory	JJ
cord-022561-rv5j1201	1471	19	impairment	impairment	NN
cord-022561-rv5j1201	1471	20	,	,	,
cord-022561-rv5j1201	1471	21	and	and	CC
cord-022561-rv5j1201	1471	22	tissue	tissue	NN
cord-022561-rv5j1201	1471	23	hypoxia	hypoxia	NN
cord-022561-rv5j1201	1471	24	.	.	.
cord-022561-rv5j1201	1472	1	Later	later	RB
cord-022561-rv5j1201	1472	2	in	in	IN
cord-022561-rv5j1201	1472	3	disease	disease	NN
cord-022561-rv5j1201	1472	4	,	,	,
cord-022561-rv5j1201	1472	5	merozoites	merozoite	NNS
cord-022561-rv5j1201	1472	6	released	release	VBN
cord-022561-rv5j1201	1472	7	from	from	IN
cord-022561-rv5j1201	1472	8	schizonts	schizont	NNS
cord-022561-rv5j1201	1472	9	enter	enter	VBP
cord-022561-rv5j1201	1472	10	erythrocytes	erythrocyte	NNS
cord-022561-rv5j1201	1472	11	,	,	,
cord-022561-rv5j1201	1472	12	resulting	result	VBG
cord-022561-rv5j1201	1472	13	in	in	IN
cord-022561-rv5j1201	1472	14	an	an	DT
cord-022561-rv5j1201	1472	15	erythrocytic	erythrocytic	JJ
cord-022561-rv5j1201	1472	16	phase	phase	NN
cord-022561-rv5j1201	1472	17	of	of	IN
cord-022561-rv5j1201	1472	18	infection	infection	NN
cord-022561-rv5j1201	1472	19	.	.	.
cord-022561-rv5j1201	1473	1	Infected	infect	VBN
cord-022561-rv5j1201	1473	2	domestic	domestic	JJ
cord-022561-rv5j1201	1473	3	cats	cat	NNS
cord-022561-rv5j1201	1473	4	often	often	RB
cord-022561-rv5j1201	1473	5	have	have	VBP
cord-022561-rv5j1201	1473	6	nonregenerative	nonregenerative	JJ
cord-022561-rv5j1201	1473	7	anemia	anemia	NN
cord-022561-rv5j1201	1473	8	,	,	,
cord-022561-rv5j1201	1473	9	but	but	CC
cord-022561-rv5j1201	1473	10	the	the	DT
cord-022561-rv5j1201	1473	11	pathogenesis	pathogenesis	NN
cord-022561-rv5j1201	1473	12	for	for	IN
cord-022561-rv5j1201	1473	13	the	the	DT
cord-022561-rv5j1201	1473	14	anemia	anemia	NN
cord-022561-rv5j1201	1473	15	is	be	VBZ
cord-022561-rv5j1201	1473	16	unclear	unclear	JJ
cord-022561-rv5j1201	1473	17	.	.	.
cord-022561-rv5j1201	1474	1	However	however	RB
cord-022561-rv5j1201	1474	2	,	,	,
cord-022561-rv5j1201	1474	3	it	-PRON-	PRP
cord-022561-rv5j1201	1474	4	likely	likely	RB
cord-022561-rv5j1201	1474	5	represents	represent	VBZ
cord-022561-rv5j1201	1474	6	preregenerative	preregenerative	JJ
cord-022561-rv5j1201	1474	7	hemolytic	hemolytic	JJ
cord-022561-rv5j1201	1474	8	anemia	anemia	NN
cord-022561-rv5j1201	1474	9	because	because	IN
cord-022561-rv5j1201	1474	10	erythrocyte	erythrocyte	NN
cord-022561-rv5j1201	1474	11	phagocytosis	phagocytosis	NN
cord-022561-rv5j1201	1474	12	is	be	VBZ
cord-022561-rv5j1201	1474	13	a	a	DT
cord-022561-rv5j1201	1474	14	prominent	prominent	JJ
cord-022561-rv5j1201	1474	15	finding	finding	NN
cord-022561-rv5j1201	1474	16	in	in	IN
cord-022561-rv5j1201	1474	17	many	many	JJ
cord-022561-rv5j1201	1474	18	organs	organ	NNS
cord-022561-rv5j1201	1474	19	.	.	.
cord-022561-rv5j1201	1475	1	Infected	infected	JJ
cord-022561-rv5j1201	1475	2	cats	cat	NNS
cord-022561-rv5j1201	1475	3	often	often	RB
cord-022561-rv5j1201	1475	4	also	also	RB
cord-022561-rv5j1201	1475	5	develop	develop	VBP
cord-022561-rv5j1201	1475	6	neutropenia	neutropenia	NN
cord-022561-rv5j1201	1475	7	and	and	CC
cord-022561-rv5j1201	1475	8	thrombocytopenia	thrombocytopenia	NN
cord-022561-rv5j1201	1475	9	,	,	,
cord-022561-rv5j1201	1475	10	which	which	WDT
cord-022561-rv5j1201	1475	11	likely	likely	RB
cord-022561-rv5j1201	1475	12	result	result	VBP
cord-022561-rv5j1201	1475	13	from	from	IN
cord-022561-rv5j1201	1475	14	inflammation	inflammation	NN
cord-022561-rv5j1201	1475	15	and	and	CC
cord-022561-rv5j1201	1475	16	disseminated	disseminate	VBN
cord-022561-rv5j1201	1475	17	intravascular	intravascular	JJ
cord-022561-rv5j1201	1475	18	coagulation	coagulation	NN
cord-022561-rv5j1201	1475	19	,	,	,
cord-022561-rv5j1201	1475	20	respectively	respectively	RB
cord-022561-rv5j1201	1475	21	.	.	.
cord-022561-rv5j1201	1476	1	On	on	IN
cord-022561-rv5j1201	1476	2	blood	blood	NN
cord-022561-rv5j1201	1476	3	smear	smear	NN
cord-022561-rv5j1201	1476	4	evaluation	evaluation	NN
cord-022561-rv5j1201	1476	5	,	,	,
cord-022561-rv5j1201	1476	6	signet	signet	NN
cord-022561-rv5j1201	1476	7	ring	ring	NN
cord-022561-rv5j1201	1476	8	-	-	HYPH
cord-022561-rv5j1201	1476	9	shaped	shape	VBN
cord-022561-rv5j1201	1476	10	erythrocytic	erythrocytic	JJ
cord-022561-rv5j1201	1476	11	inclusions	inclusion	NNS
cord-022561-rv5j1201	1476	12	(	(	-LRB-
cord-022561-rv5j1201	1476	13	piroplasms	piroplasms	NNP
cord-022561-rv5j1201	1476	14	)	)	-RRB-
cord-022561-rv5j1201	1476	15	may	may	MD
cord-022561-rv5j1201	1476	16	be	be	VB
cord-022561-rv5j1201	1476	17	observed	observe	VBN
cord-022561-rv5j1201	1476	18	during	during	IN
cord-022561-rv5j1201	1476	19	the	the	DT
cord-022561-rv5j1201	1476	20	erythrocytic	erythrocytic	JJ
cord-022561-rv5j1201	1476	21	phase	phase	NN
cord-022561-rv5j1201	1476	22	of	of	IN
cord-022561-rv5j1201	1476	23	disease	disease	NN
cord-022561-rv5j1201	1476	24	(	(	-LRB-
cord-022561-rv5j1201	1476	25	Fig	Fig	NNP
cord-022561-rv5j1201	1476	26	.	.	.
cord-022561-rv5j1201	1476	27	13	13	CD
cord-022561-rv5j1201	1476	28	-	-	SYM
cord-022561-rv5j1201	1476	29	34	34	CD
cord-022561-rv5j1201	1476	30	)	)	-RRB-
cord-022561-rv5j1201	1476	31	.	.	.
cord-022561-rv5j1201	1477	1	These	these	DT
cord-022561-rv5j1201	1477	2	inclusions	inclusion	NNS
cord-022561-rv5j1201	1477	3	closely	closely	RB
cord-022561-rv5j1201	1477	4	resemble	resemble	VBP
cord-022561-rv5j1201	1477	5	small	small	JJ
cord-022561-rv5j1201	1477	6	-	-	HYPH
cord-022561-rv5j1201	1477	7	form	form	NN
cord-022561-rv5j1201	1478	1	Babesia	Babesia	NNP
cord-022561-rv5j1201	1478	2	(	(	-LRB-
cord-022561-rv5j1201	1478	3	see	see	VB
cord-022561-rv5j1201	1478	4	Fig	Fig	NNP
cord-022561-rv5j1201	1478	5	.	.	.
cord-022561-rv5j1201	1479	1	13	13	CD
cord-022561-rv5j1201	1479	2	-	-	SYM
cord-022561-rv5j1201	1479	3	24	24	CD
cord-022561-rv5j1201	1479	4	,	,	,
cord-022561-rv5j1201	1479	5	A	a	NN
cord-022561-rv5j1201	1479	6	)	)	-RRB-
cord-022561-rv5j1201	1479	7	and	and	CC
cord-022561-rv5j1201	1479	8	some	some	DT
cord-022561-rv5j1201	1479	9	Theileria	Theileria	NNP
cord-022561-rv5j1201	1479	10	organisms	organism	NNS
cord-022561-rv5j1201	1479	11	.	.	.
cord-022561-rv5j1201	1480	1	Postmortem	postmortem	JJ
cord-022561-rv5j1201	1480	2	examination	examination	NN
cord-022561-rv5j1201	1480	3	typically	typically	RB
cord-022561-rv5j1201	1480	4	shows	show	VBZ
cord-022561-rv5j1201	1480	5	pallor	pallor	NN
cord-022561-rv5j1201	1480	6	,	,	,
cord-022561-rv5j1201	1480	7	icterus	icterus	NN
cord-022561-rv5j1201	1480	8	,	,	,
cord-022561-rv5j1201	1480	9	splenomegaly	splenomegaly	NN
cord-022561-rv5j1201	1480	10	,	,	,
cord-022561-rv5j1201	1480	11	enlarged	enlarged	JJ
cord-022561-rv5j1201	1480	12	and	and	CC
cord-022561-rv5j1201	1480	13	red	red	JJ
cord-022561-rv5j1201	1480	14	lymph	lymph	NN
cord-022561-rv5j1201	1480	15	nodes	node	NNS
cord-022561-rv5j1201	1480	16	,	,	,
cord-022561-rv5j1201	1480	17	diffuse	diffuse	VB
cord-022561-rv5j1201	1480	18	pulmonary	pulmonary	JJ
cord-022561-rv5j1201	1480	19	congestion	congestion	NN
cord-022561-rv5j1201	1480	20	and	and	CC
cord-022561-rv5j1201	1480	21	edema	edema	NN
cord-022561-rv5j1201	1480	22	,	,	,
cord-022561-rv5j1201	1480	23	and	and	CC
cord-022561-rv5j1201	1480	24	multisystemic	multisystemic	NNP
cord-022561-rv5j1201	1480	25	petechiae	petechia	NNS
cord-022561-rv5j1201	1480	26	and	and	CC
cord-022561-rv5j1201	1480	27	ecchymoses	ecchymosis	NNS
cord-022561-rv5j1201	1480	28	.	.	.
cord-022561-rv5j1201	1481	1	Vascular	vascular	JJ
cord-022561-rv5j1201	1481	2	obstruction	obstruction	NN
cord-022561-rv5j1201	1481	3	may	may	MD
cord-022561-rv5j1201	1481	4	cause	cause	VB
cord-022561-rv5j1201	1481	5	marked	mark	VBN
cord-022561-rv5j1201	1481	6	distention	distention	NN
cord-022561-rv5j1201	1481	7	of	of	IN
cord-022561-rv5j1201	1481	8	abdominal	abdominal	JJ
cord-022561-rv5j1201	1481	9	veins	vein	NNS
cord-022561-rv5j1201	1481	10	.	.	.
cord-022561-rv5j1201	1482	1	Cavitary	cavitary	JJ
cord-022561-rv5j1201	1482	2	effusions	effusion	NNS
cord-022561-rv5j1201	1482	3	are	be	VBP
cord-022561-rv5j1201	1482	4	present	present	JJ
cord-022561-rv5j1201	1482	5	in	in	IN
cord-022561-rv5j1201	1482	6	some	some	DT
cord-022561-rv5j1201	1482	7	cats	cat	NNS
cord-022561-rv5j1201	1482	8	.	.	.
cord-022561-rv5j1201	1483	1	Microscopically	microscopically	RB
cord-022561-rv5j1201	1483	2	,	,	,
cord-022561-rv5j1201	1483	3	large	large	JJ
cord-022561-rv5j1201	1483	4	,	,	,
cord-022561-rv5j1201	1483	5	schizont	schizont	JJ
cord-022561-rv5j1201	1483	6	-	-	HYPH
cord-022561-rv5j1201	1483	7	laden	laden	JJ
cord-022561-rv5j1201	1483	8	macrophages	macrophage	NNS
cord-022561-rv5j1201	1483	9	accumulate	accumulate	VBP
cord-022561-rv5j1201	1483	10	within	within	IN
cord-022561-rv5j1201	1483	11	venous	venous	JJ
cord-022561-rv5j1201	1483	12	and	and	CC
cord-022561-rv5j1201	1483	13	sinusoidal	sinusoidal	JJ
cord-022561-rv5j1201	1483	14	lumens	lumen	NNS
cord-022561-rv5j1201	1483	15	and	and	CC
cord-022561-rv5j1201	1483	16	often	often	RB
cord-022561-rv5j1201	1483	17	completely	completely	RB
cord-022561-rv5j1201	1483	18	occlude	occlude	VBP
cord-022561-rv5j1201	1483	19	the	the	DT
cord-022561-rv5j1201	1483	20	lumens	lumen	NNS
cord-022561-rv5j1201	1483	21	(	(	-LRB-
cord-022561-rv5j1201	1483	22	Fig	Fig	NNP
cord-022561-rv5j1201	1483	23	.	.	.
cord-022561-rv5j1201	1483	24	13	13	CD
cord-022561-rv5j1201	1483	25	-	-	SYM
cord-022561-rv5j1201	1483	26	35	35	CD
cord-022561-rv5j1201	1483	27	)	)	-RRB-
cord-022561-rv5j1201	1483	28	.	.	.
cord-022561-rv5j1201	1484	1	which	which	WDT
cord-022561-rv5j1201	1484	2	the	the	DT
cord-022561-rv5j1201	1484	3	B	B	NNP
cord-022561-rv5j1201	1484	4	and	and	CC
cord-022561-rv5j1201	1484	5	T	t	NN
cord-022561-rv5j1201	1484	6	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	1484	7	proliferate	proliferate	VBP
cord-022561-rv5j1201	1484	8	,	,	,
cord-022561-rv5j1201	1484	9	differentiate	differentiate	VBP
cord-022561-rv5j1201	1484	10	,	,	,
cord-022561-rv5j1201	1484	11	and	and	CC
cord-022561-rv5j1201	1484	12	mature	mature	VB
cord-022561-rv5j1201	1484	13	.	.	.
cord-022561-rv5j1201	1485	1	In	in	IN
cord-022561-rv5j1201	1485	2	mammals	mammal	NNS
cord-022561-rv5j1201	1485	3	,	,	,
cord-022561-rv5j1201	1485	4	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	1485	5	arise	arise	VBP
cord-022561-rv5j1201	1485	6	from	from	IN
cord-022561-rv5j1201	1485	7	HSCs	hsc	NNS
cord-022561-rv5j1201	1485	8	in	in	IN
cord-022561-rv5j1201	1485	9	the	the	DT
cord-022561-rv5j1201	1485	10	bone	bone	NN
cord-022561-rv5j1201	1485	11	marrow	marrow	NN
cord-022561-rv5j1201	1485	12	,	,	,
cord-022561-rv5j1201	1485	13	and	and	CC
cord-022561-rv5j1201	1485	14	B	b	NN
cord-022561-rv5j1201	1485	15	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	1485	16	continue	continue	VBP
cord-022561-rv5j1201	1485	17	to	to	TO
cord-022561-rv5j1201	1485	18	develop	develop	VB
cord-022561-rv5j1201	1485	19	at	at	IN
cord-022561-rv5j1201	1485	20	this	this	DT
cord-022561-rv5j1201	1485	21	site	site	NN
cord-022561-rv5j1201	1485	22	.	.	.
cord-022561-rv5j1201	1486	1	Ruminants	ruminant	NNS
cord-022561-rv5j1201	1486	2	also	also	RB
cord-022561-rv5j1201	1486	3	have	have	VBP
cord-022561-rv5j1201	1486	4	B	b	NN
cord-022561-rv5j1201	1486	5	lymphocyte	lymphocyte	NN
cord-022561-rv5j1201	1486	6	proliferation	proliferation	NN
cord-022561-rv5j1201	1486	7	and	and	CC
cord-022561-rv5j1201	1486	8	maturation	maturation	NN
cord-022561-rv5j1201	1486	9	within	within	IN
cord-022561-rv5j1201	1486	10	their	-PRON-	PRP$
cord-022561-rv5j1201	1486	11	Peyer	Peyer	NNP
cord-022561-rv5j1201	1486	12	's	's	POS
cord-022561-rv5j1201	1486	13	patches	patch	NNS
cord-022561-rv5j1201	1486	14	.	.	.
cord-022561-rv5j1201	1487	1	Progenitor	progenitor	NN
cord-022561-rv5j1201	1487	2	T	t	NN
cord-022561-rv5j1201	1487	3	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	1487	4	migrate	migrate	VBP
cord-022561-rv5j1201	1487	5	from	from	IN
cord-022561-rv5j1201	1487	6	bone	bone	NN
cord-022561-rv5j1201	1487	7	marrow	marrow	NN
cord-022561-rv5j1201	1487	8	to	to	TO
cord-022561-rv5j1201	1487	9	mature	mature	VB
cord-022561-rv5j1201	1487	10	and	and	CC
cord-022561-rv5j1201	1487	11	undergo	undergo	VB
cord-022561-rv5j1201	1487	12	selection	selection	NN
cord-022561-rv5j1201	1487	13	in	in	IN
cord-022561-rv5j1201	1487	14	the	the	DT
cord-022561-rv5j1201	1487	15	thymus	thymus	NN
cord-022561-rv5j1201	1487	16	.	.	.
cord-022561-rv5j1201	1488	1	The	the	DT
cord-022561-rv5j1201	1488	2	spleen	spleen	NNS
cord-022561-rv5j1201	1488	3	,	,	,
cord-022561-rv5j1201	1488	4	lymph	lymph	NN
cord-022561-rv5j1201	1488	5	nodes	node	NNS
cord-022561-rv5j1201	1488	6	,	,	,
cord-022561-rv5j1201	1488	7	and	and	CC
cord-022561-rv5j1201	1488	8	lymph	lymph	NN
cord-022561-rv5j1201	1488	9	nodules	nodule	NNS
cord-022561-rv5j1201	1488	10	are	be	VBP
cord-022561-rv5j1201	1488	11	secondary	secondary	JJ
cord-022561-rv5j1201	1488	12	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	1488	13	organs	organ	NNS
cord-022561-rv5j1201	1488	14	and	and	CC
cord-022561-rv5j1201	1488	15	are	be	VBP
cord-022561-rv5j1201	1488	16	responsible	responsible	JJ
cord-022561-rv5j1201	1488	17	for	for	IN
cord-022561-rv5j1201	1488	18	the	the	DT
cord-022561-rv5j1201	1488	19	immune	immune	JJ
cord-022561-rv5j1201	1488	20	responses	response	NNS
cord-022561-rv5j1201	1488	21	to	to	IN
cord-022561-rv5j1201	1488	22	antigens	antigen	NNS
cord-022561-rv5j1201	1488	23	,	,	,
cord-022561-rv5j1201	1488	24	such	such	JJ
cord-022561-rv5j1201	1488	25	as	as	IN
cord-022561-rv5j1201	1488	26	the	the	DT
cord-022561-rv5j1201	1488	27	production	production	NN
cord-022561-rv5j1201	1488	28	of	of	IN
cord-022561-rv5j1201	1488	29	antibody	antibody	NN
cord-022561-rv5j1201	1488	30	and	and	CC
cord-022561-rv5j1201	1488	31	cell	cell	NN
cord-022561-rv5j1201	1488	32	-	-	HYPH
cord-022561-rv5j1201	1488	33	mediated	mediate	VBN
cord-022561-rv5j1201	1488	34	immune	immune	JJ
cord-022561-rv5j1201	1488	35	reactions	reaction	NNS
cord-022561-rv5j1201	1488	36	.	.	.
cord-022561-rv5j1201	1489	1	At	at	IN
cord-022561-rv5j1201	1489	2	these	these	DT
cord-022561-rv5j1201	1489	3	sites	site	NNS
cord-022561-rv5j1201	1489	4	,	,	,
cord-022561-rv5j1201	1489	5	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	1489	6	are	be	VBP
cord-022561-rv5j1201	1489	7	activated	activate	VBN
cord-022561-rv5j1201	1489	8	by	by	IN
cord-022561-rv5j1201	1489	9	antigens	antigen	NNS
cord-022561-rv5j1201	1489	10	and	and	CC
cord-022561-rv5j1201	1489	11	undergo	undergo	VB
cord-022561-rv5j1201	1489	12	clonal	clonal	JJ
cord-022561-rv5j1201	1489	13	selection	selection	NN
cord-022561-rv5j1201	1489	14	,	,	,
cord-022561-rv5j1201	1489	15	proliferation	proliferation	NN
cord-022561-rv5j1201	1489	16	,	,	,
cord-022561-rv5j1201	1489	17	and	and	CC
cord-022561-rv5j1201	1489	18	differentiation	differentiation	NN
cord-022561-rv5j1201	1489	19	(	(	-LRB-
cord-022561-rv5j1201	1489	20	see	see	VB
cord-022561-rv5j1201	1489	21	also	also	RB
cord-022561-rv5j1201	1489	22	Chapter	chapter	NN
cord-022561-rv5j1201	1489	23	5	5	CD
cord-022561-rv5j1201	1489	24	)	)	-RRB-
cord-022561-rv5j1201	1489	25	.	.	.
cord-022561-rv5j1201	1490	1	In	in	IN
cord-022561-rv5j1201	1490	2	addition	addition	NN
cord-022561-rv5j1201	1490	3	,	,	,
cord-022561-rv5j1201	1490	4	the	the	DT
cord-022561-rv5j1201	1490	5	spleen	spleen	NNS
cord-022561-rv5j1201	1490	6	and	and	CC
cord-022561-rv5j1201	1490	7	lymph	lymph	NN
cord-022561-rv5j1201	1490	8	nodes	node	NNS
cord-022561-rv5j1201	1490	9	contain	contain	VBP
cord-022561-rv5j1201	1490	10	cells	cell	NNS
cord-022561-rv5j1201	1490	11	of	of	IN
cord-022561-rv5j1201	1490	12	the	the	DT
cord-022561-rv5j1201	1490	13	monocyte	monocyte	JJ
cord-022561-rv5j1201	1490	14	-	-	HYPH
cord-022561-rv5j1201	1490	15	macrophage	macrophage	NN
cord-022561-rv5j1201	1490	16	system	system	NN
cord-022561-rv5j1201	1490	17	and	and	CC
cord-022561-rv5j1201	1490	18	thus	thus	RB
cord-022561-rv5j1201	1490	19	also	also	RB
cord-022561-rv5j1201	1490	20	participate	participate	VB
cord-022561-rv5j1201	1490	21	in	in	IN
cord-022561-rv5j1201	1490	22	the	the	DT
cord-022561-rv5j1201	1490	23	phagocytosis	phagocytosis	NN
cord-022561-rv5j1201	1490	24	of	of	IN
cord-022561-rv5j1201	1490	25	cells	cell	NNS
cord-022561-rv5j1201	1490	26	and	and	CC
cord-022561-rv5j1201	1490	27	materials	material	NNS
cord-022561-rv5j1201	1490	28	.	.	.
cord-022561-rv5j1201	1491	1	The	the	DT
cord-022561-rv5j1201	1491	2	bone	bone	NN
cord-022561-rv5j1201	1491	3	marrow	marrow	NN
cord-022561-rv5j1201	1491	4	is	be	VBZ
cord-022561-rv5j1201	1491	5	described	describe	VBN
cord-022561-rv5j1201	1491	6	in	in	IN
cord-022561-rv5j1201	1491	7	the	the	DT
cord-022561-rv5j1201	1491	8	first	first	JJ
cord-022561-rv5j1201	1491	9	section	section	NN
cord-022561-rv5j1201	1491	10	of	of	IN
cord-022561-rv5j1201	1491	11	this	this	DT
cord-022561-rv5j1201	1491	12	chapter	chapter	NN
cord-022561-rv5j1201	1491	13	.	.	.
cord-022561-rv5j1201	1492	1	The	the	DT
cord-022561-rv5j1201	1492	2	remaining	remain	VBG
cord-022561-rv5j1201	1492	3	primary	primary	JJ
cord-022561-rv5j1201	1492	4	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	1492	5	organ	organ	NN
cord-022561-rv5j1201	1492	6	,	,	,
cord-022561-rv5j1201	1492	7	the	the	DT
cord-022561-rv5j1201	1492	8	thymus	thymus	NN
cord-022561-rv5j1201	1492	9	,	,	,
cord-022561-rv5j1201	1492	10	is	be	VBZ
cord-022561-rv5j1201	1492	11	described	describe	VBN
cord-022561-rv5j1201	1492	12	first	first	RB
cord-022561-rv5j1201	1492	13	in	in	IN
cord-022561-rv5j1201	1492	14	this	this	DT
cord-022561-rv5j1201	1492	15	section	section	NN
cord-022561-rv5j1201	1492	16	,	,	,
cord-022561-rv5j1201	1492	17	followed	follow	VBN
cord-022561-rv5j1201	1492	18	by	by	IN
cord-022561-rv5j1201	1492	19	the	the	DT
cord-022561-rv5j1201	1492	20	secondary	secondary	JJ
cord-022561-rv5j1201	1492	21	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	1492	22	organs	organ	NNS
cord-022561-rv5j1201	1492	23	:	:	:
cord-022561-rv5j1201	1492	24	spleen	spleen	NNS
cord-022561-rv5j1201	1492	25	,	,	,
cord-022561-rv5j1201	1492	26	lymph	lymph	NN
cord-022561-rv5j1201	1492	27	nodes	node	NNS
cord-022561-rv5j1201	1492	28	,	,	,
cord-022561-rv5j1201	1492	29	and	and	CC
cord-022561-rv5j1201	1492	30	diffuse	diffuse	VB
cord-022561-rv5j1201	1492	31	and	and	CC
cord-022561-rv5j1201	1492	32	nodular	nodular	JJ
cord-022561-rv5j1201	1492	33	lymphatic	lymphatic	JJ
cord-022561-rv5j1201	1492	34	tissues	tissue	NNS
cord-022561-rv5j1201	1492	35	.	.	.
cord-022561-rv5j1201	1493	1	Errors	error	NNS
cord-022561-rv5j1201	1493	2	from	from	IN
cord-022561-rv5j1201	1493	3	selection	selection	NN
cord-022561-rv5j1201	1493	4	of	of	IN
cord-022561-rv5j1201	1493	5	inappropriate	inappropriate	JJ
cord-022561-rv5j1201	1493	6	sampling	sampling	NN
cord-022561-rv5j1201	1493	7	sites	site	NNS
cord-022561-rv5j1201	1493	8	and	and	CC
cord-022561-rv5j1201	1493	9	artifacts	artifact	NNS
cord-022561-rv5j1201	1493	10	from	from	IN
cord-022561-rv5j1201	1493	11	compression	compression	NN
cord-022561-rv5j1201	1493	12	and	and	CC
cord-022561-rv5j1201	1493	13	incorrect	incorrect	JJ
cord-022561-rv5j1201	1493	14	fixation	fixation	NN
cord-022561-rv5j1201	1493	15	for	for	IN
cord-022561-rv5j1201	1493	16	histopathologic	histopathologic	NNP
cord-022561-rv5j1201	1493	17	and	and	CC
cord-022561-rv5j1201	1493	18	immunohistochemical	immunohistochemical	JJ
cord-022561-rv5j1201	1493	19	examinations	examination	NNS
cord-022561-rv5j1201	1493	20	are	be	VBP
cord-022561-rv5j1201	1493	21	common	common	JJ
cord-022561-rv5j1201	1493	22	in	in	IN
cord-022561-rv5j1201	1493	23	routine	routine	JJ
cord-022561-rv5j1201	1493	24	veterinary	veterinary	JJ
cord-022561-rv5j1201	1493	25	pathologic	pathologic	JJ
cord-022561-rv5j1201	1493	26	analysis	analysis	NN
cord-022561-rv5j1201	1493	27	.	.	.
cord-022561-rv5j1201	1494	1	The	the	DT
cord-022561-rv5j1201	1494	2	identification	identification	NN
cord-022561-rv5j1201	1494	3	and	and	CC
cord-022561-rv5j1201	1494	4	remedies	remedy	NNS
cord-022561-rv5j1201	1494	5	for	for	IN
cord-022561-rv5j1201	1494	6	these	these	DT
cord-022561-rv5j1201	1494	7	problems	problem	NNS
cord-022561-rv5j1201	1494	8	are	be	VBP
cord-022561-rv5j1201	1494	9	discussed	discuss	VBN
cord-022561-rv5j1201	1494	10	in	in	IN
cord-022561-rv5j1201	1494	11	E	E	NNP
cord-022561-rv5j1201	1494	12	-	-	NNP
cord-022561-rv5j1201	1494	13	Appendix	Appendix	NNP
cord-022561-rv5j1201	1494	14	13	13	CD
cord-022561-rv5j1201	1494	15	-	-	SYM
cord-022561-rv5j1201	1494	16	2	2	CD
cord-022561-rv5j1201	1494	17	.	.	.
cord-022561-rv5j1201	1495	1	The	the	DT
cord-022561-rv5j1201	1495	2	thymus	thymus	NN
cord-022561-rv5j1201	1495	3	is	be	VBZ
cord-022561-rv5j1201	1495	4	essential	essential	JJ
cord-022561-rv5j1201	1495	5	for	for	IN
cord-022561-rv5j1201	1495	6	the	the	DT
cord-022561-rv5j1201	1495	7	development	development	NN
cord-022561-rv5j1201	1495	8	and	and	CC
cord-022561-rv5j1201	1495	9	function	function	NN
cord-022561-rv5j1201	1495	10	of	of	IN
cord-022561-rv5j1201	1495	11	the	the	DT
cord-022561-rv5j1201	1495	12	immune	immune	JJ
cord-022561-rv5j1201	1495	13	system	system	NN
cord-022561-rv5j1201	1495	14	,	,	,
cord-022561-rv5j1201	1495	15	specifically	specifically	RB
cord-022561-rv5j1201	1495	16	for	for	IN
cord-022561-rv5j1201	1495	17	the	the	DT
cord-022561-rv5j1201	1495	18	differentiation	differentiation	NN
cord-022561-rv5j1201	1495	19	,	,	,
cord-022561-rv5j1201	1495	20	selection	selection	NN
cord-022561-rv5j1201	1495	21	,	,	,
cord-022561-rv5j1201	1495	22	and	and	CC
cord-022561-rv5j1201	1495	23	maturation	maturation	NN
cord-022561-rv5j1201	1495	24	of	of	IN
cord-022561-rv5j1201	1495	25	T	t	NN
cord-022561-rv5j1201	1495	26	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	1495	27	generated	generate	VBN
cord-022561-rv5j1201	1495	28	in	in	IN
cord-022561-rv5j1201	1495	29	the	the	DT
cord-022561-rv5j1201	1495	30	bone	bone	NN
cord-022561-rv5j1201	1495	31	marrow	marrow	NN
cord-022561-rv5j1201	1495	32	(	(	-LRB-
cord-022561-rv5j1201	1495	33	see	see	VB
cord-022561-rv5j1201	1495	34	also	also	RB
cord-022561-rv5j1201	1495	35	Chapter	chapter	NN
cord-022561-rv5j1201	1495	36	5	5	CD
cord-022561-rv5j1201	1495	37	)	)	-RRB-
cord-022561-rv5j1201	1495	38	.	.	.
cord-022561-rv5j1201	1496	1	The	the	DT
cord-022561-rv5j1201	1496	2	basic	basic	JJ
cord-022561-rv5j1201	1496	3	arrangement	arrangement	NN
cord-022561-rv5j1201	1496	4	of	of	IN
cord-022561-rv5j1201	1496	5	the	the	DT
cord-022561-rv5j1201	1496	6	thymus	thymus	NN
cord-022561-rv5j1201	1496	7	in	in	IN
cord-022561-rv5j1201	1496	8	domestic	domestic	JJ
cord-022561-rv5j1201	1496	9	animals	animal	NNS
cord-022561-rv5j1201	1496	10	consists	consist	VBZ
cord-022561-rv5j1201	1496	11	of	of	IN
cord-022561-rv5j1201	1496	12	paired	pair	VBN
cord-022561-rv5j1201	1496	13	cervical	cervical	JJ
cord-022561-rv5j1201	1496	14	lobes	lobe	NNS
cord-022561-rv5j1201	1496	15	(	(	-LRB-
cord-022561-rv5j1201	1496	16	left	left	JJ
cord-022561-rv5j1201	1496	17	and	and	CC
cord-022561-rv5j1201	1496	18	right	right	RB
cord-022561-rv5j1201	1496	19	)	)	-RRB-
cord-022561-rv5j1201	1496	20	,	,	,
cord-022561-rv5j1201	1496	21	an	an	DT
cord-022561-rv5j1201	1496	22	intermediate	intermediate	JJ
cord-022561-rv5j1201	1496	23	lobe	lobe	NN
cord-022561-rv5j1201	1496	24	at	at	IN
cord-022561-rv5j1201	1496	25	the	the	DT
cord-022561-rv5j1201	1496	26	thoracic	thoracic	JJ
cord-022561-rv5j1201	1496	27	inlet	inlet	NN
cord-022561-rv5j1201	1496	28	,	,	,
cord-022561-rv5j1201	1496	29	and	and	CC
cord-022561-rv5j1201	1496	30	a	a	DT
cord-022561-rv5j1201	1496	31	thoracic	thoracic	JJ
cord-022561-rv5j1201	1496	32	lobe	lobe	NN
cord-022561-rv5j1201	1496	33	,	,	,
cord-022561-rv5j1201	1496	34	which	which	WDT
cord-022561-rv5j1201	1496	35	may	may	MD
cord-022561-rv5j1201	1496	36	be	be	VB
cord-022561-rv5j1201	1496	37	bilobed	bilobe	VBN
cord-022561-rv5j1201	1496	38	.	.	.
cord-022561-rv5j1201	1497	1	The	the	DT
cord-022561-rv5j1201	1497	2	cervical	cervical	JJ
cord-022561-rv5j1201	1497	3	lobes	lobe	NNS
cord-022561-rv5j1201	1497	4	are	be	VBP
cord-022561-rv5j1201	1497	5	positioned	position	VBN
cord-022561-rv5j1201	1497	6	ventrolateral	ventrolateral	JJ
cord-022561-rv5j1201	1497	7	to	to	IN
cord-022561-rv5j1201	1497	8	the	the	DT
cord-022561-rv5j1201	1497	9	trachea	trachea	NN
cord-022561-rv5j1201	1497	10	,	,	,
cord-022561-rv5j1201	1497	11	adjacent	adjacent	JJ
cord-022561-rv5j1201	1497	12	to	to	IN
cord-022561-rv5j1201	1497	13	the	the	DT
cord-022561-rv5j1201	1497	14	carotid	carotid	JJ
cord-022561-rv5j1201	1497	15	arteries	artery	NNS
cord-022561-rv5j1201	1497	16	,	,	,
cord-022561-rv5j1201	1497	17	and	and	CC
cord-022561-rv5j1201	1497	18	extend	extend	VB
cord-022561-rv5j1201	1497	19	from	from	IN
cord-022561-rv5j1201	1497	20	the	the	DT
cord-022561-rv5j1201	1497	21	intermediate	intermediate	JJ
cord-022561-rv5j1201	1497	22	lobe	lobe	NN
cord-022561-rv5j1201	1497	23	at	at	IN
cord-022561-rv5j1201	1497	24	the	the	DT
cord-022561-rv5j1201	1497	25	thoracic	thoracic	JJ
cord-022561-rv5j1201	1497	26	inlet	inlet	NN
cord-022561-rv5j1201	1497	27	as	as	RB
cord-022561-rv5j1201	1497	28	far	far	RB
cord-022561-rv5j1201	1497	29	cranially	cranially	RB
cord-022561-rv5j1201	1497	30	as	as	IN
cord-022561-rv5j1201	1497	31	the	the	DT
cord-022561-rv5j1201	1497	32	larynx	larynx	NN
cord-022561-rv5j1201	1497	33	.	.	.
cord-022561-rv5j1201	1498	1	The	the	DT
cord-022561-rv5j1201	1498	2	intermediate	intermediate	JJ
cord-022561-rv5j1201	1498	3	lobe	lobe	NN
cord-022561-rv5j1201	1498	4	bridges	bridge	NNS
cord-022561-rv5j1201	1498	5	between	between	IN
cord-022561-rv5j1201	1498	6	the	the	DT
cord-022561-rv5j1201	1498	7	cervical	cervical	NN
cord-022561-rv5j1201	1498	8	and	and	CC
cord-022561-rv5j1201	1498	9	the	the	DT
cord-022561-rv5j1201	1498	10	thoracic	thoracic	JJ
cord-022561-rv5j1201	1498	11	lobe	lobe	NN
cord-022561-rv5j1201	1498	12	.	.	.
cord-022561-rv5j1201	1499	1	The	the	DT
cord-022561-rv5j1201	1499	2	right	right	JJ
cord-022561-rv5j1201	1499	3	thoracic	thoracic	JJ
cord-022561-rv5j1201	1499	4	lobe	lobe	NN
cord-022561-rv5j1201	1499	5	is	be	VBZ
cord-022561-rv5j1201	1499	6	usually	usually	RB
cord-022561-rv5j1201	1499	7	small	small	JJ
cord-022561-rv5j1201	1499	8	or	or	CC
cord-022561-rv5j1201	1499	9	completely	completely	RB
cord-022561-rv5j1201	1499	10	absent	absent	JJ
cord-022561-rv5j1201	1499	11	.	.	.
cord-022561-rv5j1201	1500	1	The	the	DT
cord-022561-rv5j1201	1500	2	left	left	JJ
cord-022561-rv5j1201	1500	3	lobe	lobe	NN
cord-022561-rv5j1201	1500	4	lies	lie	VBZ
cord-022561-rv5j1201	1500	5	in	in	IN
cord-022561-rv5j1201	1500	6	the	the	DT
cord-022561-rv5j1201	1500	7	ventral	ventral	JJ
cord-022561-rv5j1201	1500	8	aspect	aspect	NN
cord-022561-rv5j1201	1500	9	of	of	IN
cord-022561-rv5j1201	1500	10	the	the	DT
cord-022561-rv5j1201	1500	11	cranial	cranial	JJ
cord-022561-rv5j1201	1500	12	mediastinum	mediastinum	NN
cord-022561-rv5j1201	1500	13	(	(	-LRB-
cord-022561-rv5j1201	1500	14	except	except	IN
cord-022561-rv5j1201	1500	15	in	in	IN
cord-022561-rv5j1201	1500	16	the	the	DT
cord-022561-rv5j1201	1500	17	ruminant	ruminant	NN
cord-022561-rv5j1201	1500	18	,	,	,
cord-022561-rv5j1201	1500	19	where	where	WRB
cord-022561-rv5j1201	1500	20	it	-PRON-	PRP
cord-022561-rv5j1201	1500	21	is	be	VBZ
cord-022561-rv5j1201	1500	22	dorsal	dorsal	JJ
cord-022561-rv5j1201	1500	23	)	)	-RRB-
cord-022561-rv5j1201	1500	24	and	and	CC
cord-022561-rv5j1201	1500	25	extends	extend	VBZ
cord-022561-rv5j1201	1500	26	caudally	caudally	RB
cord-022561-rv5j1201	1500	27	as	as	RB
cord-022561-rv5j1201	1500	28	far	far	RB
cord-022561-rv5j1201	1500	29	as	as	IN
cord-022561-rv5j1201	1500	30	the	the	DT
cord-022561-rv5j1201	1500	31	pericardium	pericardium	NN
cord-022561-rv5j1201	1500	32	.	.	.
cord-022561-rv5j1201	1501	1	Horse	horse	NN
cord-022561-rv5j1201	1501	2	-	-	:
cord-022561-rv5j1201	1501	3	The	the	DT
cord-022561-rv5j1201	1501	4	cervical	cervical	JJ
cord-022561-rv5j1201	1501	5	lobes	lobe	NNS
cord-022561-rv5j1201	1501	6	in	in	IN
cord-022561-rv5j1201	1501	7	foals	foal	NNS
cord-022561-rv5j1201	1501	8	are	be	VBP
cord-022561-rv5j1201	1501	9	small	small	JJ
cord-022561-rv5j1201	1501	10	,	,	,
cord-022561-rv5j1201	1501	11	and	and	CC
cord-022561-rv5j1201	1501	12	the	the	DT
cord-022561-rv5j1201	1501	13	thoracic	thoracic	JJ
cord-022561-rv5j1201	1501	14	lobe	lobe	NN
cord-022561-rv5j1201	1501	15	constitutes	constitute	VBZ
cord-022561-rv5j1201	1501	16	the	the	DT
cord-022561-rv5j1201	1501	17	bulk	bulk	NN
cord-022561-rv5j1201	1501	18	of	of	IN
cord-022561-rv5j1201	1501	19	the	the	DT
cord-022561-rv5j1201	1501	20	thymus	thymus	NN
cord-022561-rv5j1201	1501	21	.	.	.
cord-022561-rv5j1201	1502	1	Ruminant-	Ruminant-	NNS
cord-022561-rv5j1201	1503	1	The	the	DT
cord-022561-rv5j1201	1503	2	cervical	cervical	JJ
cord-022561-rv5j1201	1503	3	lobes	lobe	NNS
cord-022561-rv5j1201	1503	4	are	be	VBP
cord-022561-rv5j1201	1503	5	large	large	JJ
cord-022561-rv5j1201	1503	6	.	.	.
cord-022561-rv5j1201	1504	1	The	the	DT
cord-022561-rv5j1201	1504	2	left	left	JJ
cord-022561-rv5j1201	1504	3	and	and	CC
cord-022561-rv5j1201	1504	4	right	right	JJ
cord-022561-rv5j1201	1504	5	thoracic	thoracic	JJ
cord-022561-rv5j1201	1504	6	lobes	lobe	NNS
cord-022561-rv5j1201	1504	7	are	be	VBP
cord-022561-rv5j1201	1504	8	fused	fuse	VBN
cord-022561-rv5j1201	1504	9	and	and	CC
cord-022561-rv5j1201	1504	10	unlike	unlike	IN
cord-022561-rv5j1201	1504	11	other	other	JJ
cord-022561-rv5j1201	1504	12	domestic	domestic	JJ
cord-022561-rv5j1201	1504	13	animals	animal	NNS
cord-022561-rv5j1201	1504	14	,	,	,
cord-022561-rv5j1201	1504	15	lie	lie	VB
cord-022561-rv5j1201	1504	16	in	in	IN
cord-022561-rv5j1201	1504	17	the	the	DT
cord-022561-rv5j1201	1504	18	dorsal	dorsal	JJ
cord-022561-rv5j1201	1504	19	aspect	aspect	NN
cord-022561-rv5j1201	1504	20	of	of	IN
cord-022561-rv5j1201	1504	21	the	the	DT
cord-022561-rv5j1201	1504	22	cranial	cranial	JJ
cord-022561-rv5j1201	1504	23	mediastinum	mediastinum	NN
cord-022561-rv5j1201	1504	24	.	.	.
cord-022561-rv5j1201	1505	1	Pig-	pig-	NN
cord-022561-rv5j1201	1506	1	The	the	DT
cord-022561-rv5j1201	1506	2	cervical	cervical	JJ
cord-022561-rv5j1201	1506	3	lobes	lobe	NNS
cord-022561-rv5j1201	1506	4	are	be	VBP
cord-022561-rv5j1201	1506	5	large	large	JJ
cord-022561-rv5j1201	1506	6	.	.	.
cord-022561-rv5j1201	1507	1	Dog	dog	NN
cord-022561-rv5j1201	1507	2	-	-	:
cord-022561-rv5j1201	1507	3	The	the	DT
cord-022561-rv5j1201	1507	4	cervical	cervical	JJ
cord-022561-rv5j1201	1507	5	lobes	lobe	NNS
cord-022561-rv5j1201	1507	6	regress	regress	VBP
cord-022561-rv5j1201	1507	7	very	very	RB
cord-022561-rv5j1201	1507	8	early	early	RB
cord-022561-rv5j1201	1507	9	and	and	CC
cord-022561-rv5j1201	1507	10	thus	thus	RB
cord-022561-rv5j1201	1507	11	appear	appear	VB
cord-022561-rv5j1201	1507	12	absent	absent	JJ
cord-022561-rv5j1201	1507	13	.	.	.
cord-022561-rv5j1201	1508	1	The	the	DT
cord-022561-rv5j1201	1508	2	thoracic	thoracic	JJ
cord-022561-rv5j1201	1508	3	lobe	lobe	NN
cord-022561-rv5j1201	1508	4	extends	extend	VBZ
cord-022561-rv5j1201	1508	5	caudally	caudally	RB
cord-022561-rv5j1201	1508	6	to	to	IN
cord-022561-rv5j1201	1508	7	the	the	DT
cord-022561-rv5j1201	1508	8	pericardium	pericardium	NN
cord-022561-rv5j1201	1508	9	.	.	.
cord-022561-rv5j1201	1509	1	Cat-	Cat-	NNP
cord-022561-rv5j1201	1510	1	The	the	DT
cord-022561-rv5j1201	1510	2	cervical	cervical	JJ
cord-022561-rv5j1201	1510	3	lobes	lobe	NNS
cord-022561-rv5j1201	1510	4	are	be	VBP
cord-022561-rv5j1201	1510	5	small	small	JJ
cord-022561-rv5j1201	1510	6	,	,	,
cord-022561-rv5j1201	1510	7	and	and	CC
cord-022561-rv5j1201	1510	8	the	the	DT
cord-022561-rv5j1201	1510	9	thoracic	thoracic	JJ
cord-022561-rv5j1201	1510	10	lobe	lobe	NN
cord-022561-rv5j1201	1510	11	,	,	,
cord-022561-rv5j1201	1510	12	which	which	WDT
cord-022561-rv5j1201	1510	13	forms	form	VBZ
cord-022561-rv5j1201	1510	14	the	the	DT
cord-022561-rv5j1201	1510	15	majority	majority	NN
cord-022561-rv5j1201	1510	16	of	of	IN
cord-022561-rv5j1201	1510	17	the	the	DT
cord-022561-rv5j1201	1510	18	thymus	thymus	NN
cord-022561-rv5j1201	1510	19	,	,	,
cord-022561-rv5j1201	1510	20	extends	extend	VBZ
cord-022561-rv5j1201	1510	21	caudally	caudally	RB
cord-022561-rv5j1201	1510	22	to	to	IN
cord-022561-rv5j1201	1510	23	the	the	DT
cord-022561-rv5j1201	1510	24	pericardium	pericardium	NN
cord-022561-rv5j1201	1510	25	and	and	CC
cord-022561-rv5j1201	1510	26	molds	mold	NNS
cord-022561-rv5j1201	1510	27	to	to	IN
cord-022561-rv5j1201	1510	28	its	-PRON-	PRP$
cord-022561-rv5j1201	1510	29	surface	surface	NN
cord-022561-rv5j1201	1510	30	.	.	.
cord-022561-rv5j1201	1511	1	The	the	DT
cord-022561-rv5j1201	1511	2	thymus	thymus	NN
cord-022561-rv5j1201	1511	3	is	be	VBZ
cord-022561-rv5j1201	1511	4	referred	refer	VBN
cord-022561-rv5j1201	1511	5	to	to	IN
cord-022561-rv5j1201	1511	6	as	as	IN
cord-022561-rv5j1201	1511	7	a	a	DT
cord-022561-rv5j1201	1511	8	lymphoepithelial	lymphoepithelial	JJ
cord-022561-rv5j1201	1511	9	organ	organ	NN
cord-022561-rv5j1201	1511	10	and	and	CC
cord-022561-rv5j1201	1511	11	hence	hence	RB
cord-022561-rv5j1201	1511	12	is	be	VBZ
cord-022561-rv5j1201	1511	13	composed	compose	VBN
cord-022561-rv5j1201	1511	14	of	of	IN
cord-022561-rv5j1201	1511	15	epithelial	epithelial	JJ
cord-022561-rv5j1201	1511	16	and	and	CC
cord-022561-rv5j1201	1511	17	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	1511	18	tissue	tissue	NN
cord-022561-rv5j1201	1511	19	.	.	.
cord-022561-rv5j1201	1512	1	Formed	form	VBN
cord-022561-rv5j1201	1512	2	from	from	IN
cord-022561-rv5j1201	1512	3	the	the	DT
cord-022561-rv5j1201	1512	4	endoderm	endoderm	NNS
cord-022561-rv5j1201	1512	5	of	of	IN
cord-022561-rv5j1201	1512	6	the	the	DT
cord-022561-rv5j1201	1512	7	third	third	JJ
cord-022561-rv5j1201	1512	8	pharyngeal	pharyngeal	JJ
cord-022561-rv5j1201	1512	9	pouch	pouch	NN
cord-022561-rv5j1201	1512	10	in	in	IN
cord-022561-rv5j1201	1512	11	the	the	DT
cord-022561-rv5j1201	1512	12	fetus	fetus	NN
cord-022561-rv5j1201	1512	13	,	,	,
cord-022561-rv5j1201	1512	14	the	the	DT
cord-022561-rv5j1201	1512	15	thymic	thymic	JJ
cord-022561-rv5j1201	1512	16	epithelium	epithelium	NN
cord-022561-rv5j1201	1512	17	is	be	VBZ
cord-022561-rv5j1201	1512	18	infiltrated	infiltrate	VBN
cord-022561-rv5j1201	1512	19	by	by	IN
cord-022561-rv5j1201	1512	20	blood	blood	NN
cord-022561-rv5j1201	1512	21	vessels	vessel	NNS
cord-022561-rv5j1201	1512	22	from	from	IN
cord-022561-rv5j1201	1512	23	the	the	DT
cord-022561-rv5j1201	1512	24	surrounding	surround	VBG
cord-022561-rv5j1201	1512	25	mesoderm	mesoderm	NNS
cord-022561-rv5j1201	1512	26	,	,	,
cord-022561-rv5j1201	1512	27	resulting	result	VBG
cord-022561-rv5j1201	1512	28	in	in	IN
cord-022561-rv5j1201	1512	29	the	the	DT
cord-022561-rv5j1201	1512	30	development	development	NN
cord-022561-rv5j1201	1512	31	of	of	IN
cord-022561-rv5j1201	1512	32	the	the	DT
cord-022561-rv5j1201	1512	33	thymic	thymic	JJ
cord-022561-rv5j1201	1512	34	epithelial	epithelial	JJ
cord-022561-rv5j1201	1512	35	reticulum	reticulum	NN
cord-022561-rv5j1201	1512	36	.	.	.
cord-022561-rv5j1201	1513	1	The	the	DT
cord-022561-rv5j1201	1513	2	lymphocyte	lymphocyte	NN
cord-022561-rv5j1201	1513	3	population	population	NN
cord-022561-rv5j1201	1513	4	consists	consist	VBZ
cord-022561-rv5j1201	1513	5	of	of	IN
cord-022561-rv5j1201	1513	6	bone	bone	NN
cord-022561-rv5j1201	1513	7	marrow	marrow	NN
cord-022561-rv5j1201	1513	8	-	-	HYPH
cord-022561-rv5j1201	1513	9	derived	derive	VBN
cord-022561-rv5j1201	1513	10	progenitor	progenitor	NN
cord-022561-rv5j1201	1513	11	cells	cell	NNS
cord-022561-rv5j1201	1513	12	,	,	,
cord-022561-rv5j1201	1513	13	which	which	WDT
cord-022561-rv5j1201	1513	14	fill	fill	VBP
cord-022561-rv5j1201	1513	15	spaces	space	NNS
cord-022561-rv5j1201	1513	16	within	within	IN
cord-022561-rv5j1201	1513	17	the	the	DT
cord-022561-rv5j1201	1513	18	epithelial	epithelial	JJ
cord-022561-rv5j1201	1513	19	network	network	NN
cord-022561-rv5j1201	1513	20	.	.	.
cord-022561-rv5j1201	1514	1	A	a	DT
cord-022561-rv5j1201	1514	2	connective	connective	JJ
cord-022561-rv5j1201	1514	3	tissue	tissue	NN
cord-022561-rv5j1201	1514	4	capsule	capsule	NN
cord-022561-rv5j1201	1514	5	surrounds	surround	VBZ
cord-022561-rv5j1201	1514	6	the	the	DT
cord-022561-rv5j1201	1514	7	thymus	thymus	NN
cord-022561-rv5j1201	1514	8	,	,	,
cord-022561-rv5j1201	1514	9	and	and	CC
cord-022561-rv5j1201	1514	10	attached	attach	VBD
cord-022561-rv5j1201	1514	11	thin	thin	JJ
cord-022561-rv5j1201	1514	12	septa	septa	NN
cord-022561-rv5j1201	1514	13	subdivide	subdivide	VB
cord-022561-rv5j1201	1514	14	the	the	DT
cord-022561-rv5j1201	1514	15	tissue	tissue	NN
cord-022561-rv5j1201	1514	16	into	into	IN
cord-022561-rv5j1201	1514	17	partially	partially	RB
cord-022561-rv5j1201	1514	18	separated	separate	VBN
cord-022561-rv5j1201	1514	19	lobules	lobule	NNS
cord-022561-rv5j1201	1514	20	.	.	.
cord-022561-rv5j1201	1515	1	Each	each	DT
cord-022561-rv5j1201	1515	2	report	report	NN
cord-022561-rv5j1201	1515	3	,	,	,
cord-022561-rv5j1201	1515	4	in	in	IN
cord-022561-rv5j1201	1515	5	which	which	WDT
cord-022561-rv5j1201	1515	6	numerous	numerous	JJ
cord-022561-rv5j1201	1515	7	cats	cat	NNS
cord-022561-rv5j1201	1515	8	from	from	IN
cord-022561-rv5j1201	1515	9	a	a	DT
cord-022561-rv5j1201	1515	10	subregion	subregion	NN
cord-022561-rv5j1201	1515	11	of	of	IN
cord-022561-rv5j1201	1515	12	the	the	DT
cord-022561-rv5j1201	1515	13	endemic	endemic	JJ
cord-022561-rv5j1201	1515	14	area	area	NN
cord-022561-rv5j1201	1515	15	in	in	IN
cord-022561-rv5j1201	1515	16	the	the	DT
cord-022561-rv5j1201	1515	17	United	United	NNP
cord-022561-rv5j1201	1515	18	States	States	NNP
cord-022561-rv5j1201	1515	19	survived	survive	VBD
cord-022561-rv5j1201	1515	20	infection	infection	NN
cord-022561-rv5j1201	1515	21	with	with	IN
cord-022561-rv5j1201	1515	22	an	an	DT
cord-022561-rv5j1201	1515	23	organism	organism	NN
cord-022561-rv5j1201	1515	24	with	with	IN
cord-022561-rv5j1201	1515	25	greater	great	JJR
cord-022561-rv5j1201	1515	26	than	than	IN
cord-022561-rv5j1201	1515	27	99	99	CD
cord-022561-rv5j1201	1515	28	%	%	NN
cord-022561-rv5j1201	1515	29	homology	homology	NN
cord-022561-rv5j1201	1515	30	to	to	IN
cord-022561-rv5j1201	1515	31	Cytauxzoon	Cytauxzoon	NNP
cord-022561-rv5j1201	1515	32	felis	felis	NNP
cord-022561-rv5j1201	1515	33	,	,	,
cord-022561-rv5j1201	1515	34	suggests	suggest	VBZ
cord-022561-rv5j1201	1515	35	the	the	DT
cord-022561-rv5j1201	1515	36	emergence	emergence	NN
cord-022561-rv5j1201	1515	37	of	of	IN
cord-022561-rv5j1201	1515	38	a	a	DT
cord-022561-rv5j1201	1515	39	less	less	RBR
cord-022561-rv5j1201	1515	40	virulent	virulent	JJ
cord-022561-rv5j1201	1515	41	strain	strain	NN
cord-022561-rv5j1201	1515	42	.	.	.
cord-022561-rv5j1201	1516	1	FeLV	FeLV	NNP
cord-022561-rv5j1201	1516	2	is	be	VBZ
cord-022561-rv5j1201	1516	3	an	an	DT
cord-022561-rv5j1201	1516	4	oncogenic	oncogenic	JJ
cord-022561-rv5j1201	1516	5	,	,	,
cord-022561-rv5j1201	1516	6	immunosuppressive	immunosuppressive	JJ
cord-022561-rv5j1201	1516	7	lentivirus	lentivirus	NN
cord-022561-rv5j1201	1516	8	that	that	WDT
cord-022561-rv5j1201	1516	9	causes	cause	VBZ
cord-022561-rv5j1201	1516	10	hematologic	hematologic	JJ
cord-022561-rv5j1201	1516	11	abnormalities	abnormality	NNS
cord-022561-rv5j1201	1516	12	of	of	IN
cord-022561-rv5j1201	1516	13	widely	widely	RB
cord-022561-rv5j1201	1516	14	varying	vary	VBG
cord-022561-rv5j1201	1516	15	types	type	NNS
cord-022561-rv5j1201	1516	16	and	and	CC
cord-022561-rv5j1201	1516	17	severity	severity	NN
cord-022561-rv5j1201	1516	18	.	.	.
cord-022561-rv5j1201	1517	1	Manifestations	manifestation	NNS
cord-022561-rv5j1201	1517	2	of	of	IN
cord-022561-rv5j1201	1517	3	disease	disease	NN
cord-022561-rv5j1201	1517	4	caused	cause	VBN
cord-022561-rv5j1201	1517	5	by	by	IN
cord-022561-rv5j1201	1517	6	FeLV	FeLV	NNP
cord-022561-rv5j1201	1517	7	infection	infection	NN
cord-022561-rv5j1201	1517	8	vary	vary	VBP
cord-022561-rv5j1201	1517	9	depending	depend	VBG
cord-022561-rv5j1201	1517	10	on	on	IN
cord-022561-rv5j1201	1517	11	dose	dose	NN
cord-022561-rv5j1201	1517	12	,	,	,
cord-022561-rv5j1201	1517	13	viral	viral	JJ
cord-022561-rv5j1201	1517	14	genetics	genetic	NNS
cord-022561-rv5j1201	1517	15	,	,	,
cord-022561-rv5j1201	1517	16	and	and	CC
cord-022561-rv5j1201	1517	17	host	host	NN
cord-022561-rv5j1201	1517	18	factors	factor	NNS
cord-022561-rv5j1201	1517	19	,	,	,
cord-022561-rv5j1201	1517	20	but	but	CC
cord-022561-rv5j1201	1517	21	normal	normal	JJ
cord-022561-rv5j1201	1517	22	hematopoiesis	hematopoiesis	NN
cord-022561-rv5j1201	1517	23	is	be	VBZ
cord-022561-rv5j1201	1517	24	probably	probably	RB
cord-022561-rv5j1201	1517	25	suppressed	suppress	VBN
cord-022561-rv5j1201	1517	26	to	to	IN
cord-022561-rv5j1201	1517	27	some	some	DT
cord-022561-rv5j1201	1517	28	degree	degree	NN
cord-022561-rv5j1201	1517	29	in	in	IN
cord-022561-rv5j1201	1517	30	all	all	DT
cord-022561-rv5j1201	1517	31	cases	case	NNS
cord-022561-rv5j1201	1517	32	.	.	.
cord-022561-rv5j1201	1518	1	FeLV	FeLV	NNP
cord-022561-rv5j1201	1518	2	infects	infect	VBZ
cord-022561-rv5j1201	1518	3	hematopoietic	hematopoietic	JJ
cord-022561-rv5j1201	1518	4	precursor	precursor	NN
cord-022561-rv5j1201	1518	5	cells	cell	NNS
cord-022561-rv5j1201	1518	6	soon	soon	RB
cord-022561-rv5j1201	1518	7	after	after	IN
cord-022561-rv5j1201	1518	8	the	the	DT
cord-022561-rv5j1201	1518	9	animal	animal	NN
cord-022561-rv5j1201	1518	10	is	be	VBZ
cord-022561-rv5j1201	1518	11	exposed	expose	VBN
cord-022561-rv5j1201	1518	12	and	and	CC
cord-022561-rv5j1201	1518	13	continues	continue	VBZ
cord-022561-rv5j1201	1518	14	to	to	TO
cord-022561-rv5j1201	1518	15	replicate	replicate	VB
cord-022561-rv5j1201	1518	16	in	in	IN
cord-022561-rv5j1201	1518	17	hematopoietic	hematopoietic	JJ
cord-022561-rv5j1201	1518	18	and	and	CC
cord-022561-rv5j1201	1518	19	lymphatic	lymphatic	JJ
cord-022561-rv5j1201	1518	20	tissue	tissue	NN
cord-022561-rv5j1201	1518	21	of	of	IN
cord-022561-rv5j1201	1518	22	animals	animal	NNS
cord-022561-rv5j1201	1518	23	that	that	WDT
cord-022561-rv5j1201	1518	24	remain	remain	VBP
cord-022561-rv5j1201	1518	25	persistently	persistently	RB
cord-022561-rv5j1201	1518	26	viremic	viremic	JJ
cord-022561-rv5j1201	1518	27	.	.	.
cord-022561-rv5j1201	1519	1	The	the	DT
cord-022561-rv5j1201	1519	2	virus	virus	NN
cord-022561-rv5j1201	1519	3	disrupts	disrupt	VBZ
cord-022561-rv5j1201	1519	4	normal	normal	JJ
cord-022561-rv5j1201	1519	5	hematopoiesis	hematopoiesis	NN
cord-022561-rv5j1201	1519	6	by	by	IN
cord-022561-rv5j1201	1519	7	inducing	induce	VBG
cord-022561-rv5j1201	1519	8	genetic	genetic	JJ
cord-022561-rv5j1201	1519	9	mutations	mutation	NNS
cord-022561-rv5j1201	1519	10	,	,	,
cord-022561-rv5j1201	1519	11	by	by	IN
cord-022561-rv5j1201	1519	12	other	other	JJ
cord-022561-rv5j1201	1519	13	direct	direct	JJ
cord-022561-rv5j1201	1519	14	effects	effect	NNS
cord-022561-rv5j1201	1519	15	of	of	IN
cord-022561-rv5j1201	1519	16	the	the	DT
cord-022561-rv5j1201	1519	17	virus	virus	NN
cord-022561-rv5j1201	1519	18	on	on	IN
cord-022561-rv5j1201	1519	19	infected	infected	JJ
cord-022561-rv5j1201	1519	20	hematopoietic	hematopoietic	JJ
cord-022561-rv5j1201	1519	21	cells	cell	NNS
cord-022561-rv5j1201	1519	22	,	,	,
cord-022561-rv5j1201	1519	23	or	or	CC
cord-022561-rv5j1201	1519	24	by	by	IN
cord-022561-rv5j1201	1519	25	an	an	DT
cord-022561-rv5j1201	1519	26	altered	altered	JJ
cord-022561-rv5j1201	1519	27	host	host	NN
cord-022561-rv5j1201	1519	28	immune	immune	NN
cord-022561-rv5j1201	1519	29	system	system	NN
cord-022561-rv5j1201	1519	30	.	.	.
cord-022561-rv5j1201	1520	1	Hematologic	Hematologic	NNP
cord-022561-rv5j1201	1520	2	changes	change	NNS
cord-022561-rv5j1201	1520	3	include	include	VBP
cord-022561-rv5j1201	1520	4	dysmyelopoiesis	dysmyelopoiesis	NN
cord-022561-rv5j1201	1520	5	with	with	IN
cord-022561-rv5j1201	1520	6	resultant	resultant	JJ
cord-022561-rv5j1201	1520	7	cytopenias	cytopenia	NNS
cord-022561-rv5j1201	1520	8	or	or	CC
cord-022561-rv5j1201	1520	9	abnormal	abnormal	JJ
cord-022561-rv5j1201	1520	10	cell	cell	NN
cord-022561-rv5j1201	1520	11	morphologic	morphologic	JJ
cord-022561-rv5j1201	1520	12	features	feature	NNS
cord-022561-rv5j1201	1520	13	,	,	,
cord-022561-rv5j1201	1520	14	and	and	CC
cord-022561-rv5j1201	1520	15	neoplastic	neoplastic	JJ
cord-022561-rv5j1201	1520	16	transformation	transformation	NN
cord-022561-rv5j1201	1520	17	of	of	IN
cord-022561-rv5j1201	1520	18	hematopoietic	hematopoietic	JJ
cord-022561-rv5j1201	1520	19	cells	cell	NNS
cord-022561-rv5j1201	1520	20	(	(	-LRB-
cord-022561-rv5j1201	1520	21	leukemia	leukemia	NN
cord-022561-rv5j1201	1520	22	)	)	-RRB-
cord-022561-rv5j1201	1520	23	.	.	.
cord-022561-rv5j1201	1521	1	A	a	DT
cord-022561-rv5j1201	1521	2	notable	notable	JJ
cord-022561-rv5j1201	1521	3	form	form	NN
cord-022561-rv5j1201	1521	4	of	of	IN
cord-022561-rv5j1201	1521	5	dysplasia	dysplasia	NN
cord-022561-rv5j1201	1521	6	is	be	VBZ
cord-022561-rv5j1201	1521	7	the	the	DT
cord-022561-rv5j1201	1521	8	presence	presence	NN
cord-022561-rv5j1201	1521	9	of	of	IN
cord-022561-rv5j1201	1521	10	macrocytic	macrocytic	JJ
cord-022561-rv5j1201	1521	11	erythrocytes	erythrocyte	NNS
cord-022561-rv5j1201	1521	12	(	(	-LRB-
cord-022561-rv5j1201	1521	13	macrocytes	macrocytes	NNP
cord-022561-rv5j1201	1521	14	)	)	-RRB-
cord-022561-rv5j1201	1521	15	and	and	CC
cord-022561-rv5j1201	1521	16	metarubricytosis	metarubricytosis	NN
cord-022561-rv5j1201	1521	17	in	in	IN
cord-022561-rv5j1201	1521	18	the	the	DT
cord-022561-rv5j1201	1521	19	absence	absence	NN
cord-022561-rv5j1201	1521	20	of	of	IN
cord-022561-rv5j1201	1521	21	erythrocyte	erythrocyte	NN
cord-022561-rv5j1201	1521	22	regeneration	regeneration	NN
cord-022561-rv5j1201	1521	23	(	(	-LRB-
cord-022561-rv5j1201	1521	24	inappropriate	inappropriate	JJ
cord-022561-rv5j1201	1521	25	metarubricytosis	metarubricytosis	NN
cord-022561-rv5j1201	1521	26	)	)	-RRB-
cord-022561-rv5j1201	1521	27	.	.	.
cord-022561-rv5j1201	1522	1	The	the	DT
cord-022561-rv5j1201	1522	2	relatively	relatively	RB
cord-022561-rv5j1201	1522	3	uncommon	uncommon	JJ
cord-022561-rv5j1201	1522	4	subgroup	subgroup	NN
cord-022561-rv5j1201	1522	5	C	c	NN
cord-022561-rv5j1201	1522	6	viruses	virus	NNS
cord-022561-rv5j1201	1522	7	cause	cause	VBP
cord-022561-rv5j1201	1522	8	erythroid	erythroid	JJ
cord-022561-rv5j1201	1522	9	hypoplasia	hypoplasia	NN
cord-022561-rv5j1201	1522	10	,	,	,
cord-022561-rv5j1201	1522	11	probably	probably	RB
cord-022561-rv5j1201	1522	12	because	because	IN
cord-022561-rv5j1201	1522	13	of	of	IN
cord-022561-rv5j1201	1522	14	infection	infection	NN
cord-022561-rv5j1201	1522	15	of	of	IN
cord-022561-rv5j1201	1522	16	early	early	JJ
cord-022561-rv5j1201	1522	17	-	-	HYPH
cord-022561-rv5j1201	1522	18	stage	stage	NN
cord-022561-rv5j1201	1522	19	erythroid	erythroid	NN
cord-022561-rv5j1201	1522	20	precursors	precursor	NNS
cord-022561-rv5j1201	1522	21	.	.	.
cord-022561-rv5j1201	1523	1	FeLV	FeLV	NNP
cord-022561-rv5j1201	1523	2	may	may	MD
cord-022561-rv5j1201	1523	3	be	be	VB
cord-022561-rv5j1201	1523	4	detected	detect	VBN
cord-022561-rv5j1201	1523	5	in	in	IN
cord-022561-rv5j1201	1523	6	megakaryocytes	megakaryocyte	NNS
cord-022561-rv5j1201	1523	7	and	and	CC
cord-022561-rv5j1201	1523	8	platelets	platelet	NNS
cord-022561-rv5j1201	1523	9	in	in	IN
cord-022561-rv5j1201	1523	10	infected	infected	JJ
cord-022561-rv5j1201	1523	11	cats	cat	NNS
cord-022561-rv5j1201	1523	12	and	and	CC
cord-022561-rv5j1201	1523	13	may	may	MD
cord-022561-rv5j1201	1523	14	result	result	VB
cord-022561-rv5j1201	1523	15	in	in	IN
cord-022561-rv5j1201	1523	16	platelet	platelet	NN
cord-022561-rv5j1201	1523	17	abnormalities	abnormality	NNS
cord-022561-rv5j1201	1523	18	,	,	,
cord-022561-rv5j1201	1523	19	including	include	VBG
cord-022561-rv5j1201	1523	20	thrombocytopenia	thrombocytopenia	NN
cord-022561-rv5j1201	1523	21	,	,	,
cord-022561-rv5j1201	1523	22	thrombocytosis	thrombocytosis	NNP
cord-022561-rv5j1201	1523	23	,	,	,
cord-022561-rv5j1201	1523	24	increased	increase	VBN
cord-022561-rv5j1201	1523	25	platelet	platelet	NN
cord-022561-rv5j1201	1523	26	size	size	NN
cord-022561-rv5j1201	1523	27	,	,	,
cord-022561-rv5j1201	1523	28	and	and	CC
cord-022561-rv5j1201	1523	29	decreased	decrease	VBD
cord-022561-rv5j1201	1523	30	function	function	NN
cord-022561-rv5j1201	1523	31	.	.	.
cord-022561-rv5j1201	1524	1	Proposed	propose	VBN
cord-022561-rv5j1201	1524	2	mechanisms	mechanism	NNS
cord-022561-rv5j1201	1524	3	of	of	IN
cord-022561-rv5j1201	1524	4	FeLV	felv	NN
cord-022561-rv5j1201	1524	5	-	-	HYPH
cord-022561-rv5j1201	1524	6	induced	induce	VBN
cord-022561-rv5j1201	1524	7	thrombocytopenia	thrombocytopenia	NN
cord-022561-rv5j1201	1524	8	include	include	VBP
cord-022561-rv5j1201	1524	9	direct	direct	JJ
cord-022561-rv5j1201	1524	10	cytopathic	cytopathic	JJ
cord-022561-rv5j1201	1524	11	effects	effect	NNS
cord-022561-rv5j1201	1524	12	,	,	,
cord-022561-rv5j1201	1524	13	myelophthisis	myelophthisis	NN
cord-022561-rv5j1201	1524	14	,	,	,
cord-022561-rv5j1201	1524	15	and	and	CC
cord-022561-rv5j1201	1524	16	immunemediated	immunemediated	JJ
cord-022561-rv5j1201	1524	17	destruction	destruction	NN
cord-022561-rv5j1201	1524	18	.	.	.
cord-022561-rv5j1201	1525	1	Platelet	platelet	NN
cord-022561-rv5j1201	1525	2	life	life	NN
cord-022561-rv5j1201	1525	3	span	span	NN
cord-022561-rv5j1201	1525	4	and	and	CC
cord-022561-rv5j1201	1525	5	function	function	NN
cord-022561-rv5j1201	1525	6	have	have	VBP
cord-022561-rv5j1201	1525	7	been	be	VBN
cord-022561-rv5j1201	1525	8	shown	show	VBN
cord-022561-rv5j1201	1525	9	to	to	TO
cord-022561-rv5j1201	1525	10	be	be	VB
cord-022561-rv5j1201	1525	11	decreased	decrease	VBN
cord-022561-rv5j1201	1525	12	in	in	IN
cord-022561-rv5j1201	1525	13	FeLV	felv	NN
cord-022561-rv5j1201	1525	14	-	-	HYPH
cord-022561-rv5j1201	1525	15	positive	positive	JJ
cord-022561-rv5j1201	1525	16	cats	cat	NNS
cord-022561-rv5j1201	1525	17	.	.	.
cord-022561-rv5j1201	1526	1	Persistently	persistently	RB
cord-022561-rv5j1201	1526	2	viremic	viremic	JJ
cord-022561-rv5j1201	1526	3	cats	cat	NNS
cord-022561-rv5j1201	1526	4	are	be	VBP
cord-022561-rv5j1201	1526	5	immunosuppressed	immunosuppressed	JJ
cord-022561-rv5j1201	1526	6	and	and	CC
cord-022561-rv5j1201	1526	7	are	be	VBP
cord-022561-rv5j1201	1526	8	prone	prone	JJ
cord-022561-rv5j1201	1526	9	to	to	IN
cord-022561-rv5j1201	1526	10	developing	develop	VBG
cord-022561-rv5j1201	1526	11	other	other	JJ
cord-022561-rv5j1201	1526	12	diseases	disease	NNS
cord-022561-rv5j1201	1526	13	,	,	,
cord-022561-rv5j1201	1526	14	including	include	VBG
cord-022561-rv5j1201	1526	15	infectious	infectious	JJ
cord-022561-rv5j1201	1526	16	diseases	disease	NNS
cord-022561-rv5j1201	1526	17	,	,	,
cord-022561-rv5j1201	1526	18	bone	bone	NN
cord-022561-rv5j1201	1526	19	marrow	marrow	NN
cord-022561-rv5j1201	1526	20	disorders	disorder	NNS
cord-022561-rv5j1201	1526	21	,	,	,
cord-022561-rv5j1201	1526	22	and	and	CC
cord-022561-rv5j1201	1526	23	lymphoma	lymphoma	NN
cord-022561-rv5j1201	1526	24	.	.	.
cord-022561-rv5j1201	1527	1	CBC	CBC	NNP
cord-022561-rv5j1201	1527	2	abnormalities	abnormality	NNS
cord-022561-rv5j1201	1527	3	attributed	attribute	VBN
cord-022561-rv5j1201	1527	4	to	to	IN
cord-022561-rv5j1201	1527	5	FeLV	felv	NN
cord-022561-rv5j1201	1527	6	infection	infection	NN
cord-022561-rv5j1201	1527	7	include	include	VBP
cord-022561-rv5j1201	1527	8	various	various	JJ
cord-022561-rv5j1201	1527	9	cytopenias	cytopenia	NNS
cord-022561-rv5j1201	1527	10	,	,	,
cord-022561-rv5j1201	1527	11	especially	especially	RB
cord-022561-rv5j1201	1527	12	nonregenerative	nonregenerative	JJ
cord-022561-rv5j1201	1527	13	anemia	anemia	NN
cord-022561-rv5j1201	1527	14	,	,	,
cord-022561-rv5j1201	1527	15	which	which	WDT
cord-022561-rv5j1201	1527	16	may	may	MD
cord-022561-rv5j1201	1527	17	be	be	VB
cord-022561-rv5j1201	1527	18	persistent	persistent	JJ
cord-022561-rv5j1201	1527	19	or	or	CC
cord-022561-rv5j1201	1527	20	cyclical	cyclical	JJ
cord-022561-rv5j1201	1527	21	.	.	.
cord-022561-rv5j1201	1528	1	Regenerative	regenerative	JJ
cord-022561-rv5j1201	1528	2	anemia	anemia	NN
cord-022561-rv5j1201	1528	3	may	may	MD
cord-022561-rv5j1201	1528	4	also	also	RB
cord-022561-rv5j1201	1528	5	occur	occur	VB
cord-022561-rv5j1201	1528	6	with	with	IN
cord-022561-rv5j1201	1528	7	FeLV	felv	NN
cord-022561-rv5j1201	1528	8	infection	infection	NN
cord-022561-rv5j1201	1528	9	,	,	,
cord-022561-rv5j1201	1528	10	often	often	RB
cord-022561-rv5j1201	1528	11	because	because	IN
cord-022561-rv5j1201	1528	12	of	of	IN
cord-022561-rv5j1201	1528	13	coinfection	coinfection	NN
cord-022561-rv5j1201	1528	14	with	with	IN
cord-022561-rv5j1201	1528	15	M.	M.	NNP
cord-022561-rv5j1201	1528	16	haemofelis	haemofelis	NNP
cord-022561-rv5j1201	1528	17	.	.	.
cord-022561-rv5j1201	1529	1	Hematopoietic	hematopoietic	JJ
cord-022561-rv5j1201	1529	2	cell	cell	NN
cord-022561-rv5j1201	1529	3	dysplasia	dysplasia	NN
cord-022561-rv5j1201	1529	4	or	or	CC
cord-022561-rv5j1201	1529	5	neoplasia	neoplasia	NN
cord-022561-rv5j1201	1529	6	may	may	MD
cord-022561-rv5j1201	1529	7	also	also	RB
cord-022561-rv5j1201	1529	8	be	be	VB
cord-022561-rv5j1201	1529	9	evident	evident	JJ
cord-022561-rv5j1201	1529	10	.	.	.
cord-022561-rv5j1201	1530	1	Grossly	grossly	RB
cord-022561-rv5j1201	1530	2	,	,	,
cord-022561-rv5j1201	1530	3	infected	infected	JJ
cord-022561-rv5j1201	1530	4	cats	cat	NNS
cord-022561-rv5j1201	1530	5	are	be	VBP
cord-022561-rv5j1201	1530	6	often	often	RB
cord-022561-rv5j1201	1530	7	pale	pale	JJ
cord-022561-rv5j1201	1530	8	,	,	,
cord-022561-rv5j1201	1530	9	but	but	CC
cord-022561-rv5j1201	1530	10	other	other	JJ
cord-022561-rv5j1201	1530	11	lesions	lesion	NNS
cord-022561-rv5j1201	1530	12	are	be	VBP
cord-022561-rv5j1201	1530	13	dependent	dependent	JJ
cord-022561-rv5j1201	1530	14	upon	upon	IN
cord-022561-rv5j1201	1530	15	the	the	DT
cord-022561-rv5j1201	1530	16	presence	presence	NN
cord-022561-rv5j1201	1530	17	of	of	IN
cord-022561-rv5j1201	1530	18	other	other	JJ
cord-022561-rv5j1201	1530	19	cytopenias	cytopenia	NNS
cord-022561-rv5j1201	1530	20	or	or	CC
cord-022561-rv5j1201	1530	21	concurrent	concurrent	JJ
cord-022561-rv5j1201	1530	22	disease	disease	NN
cord-022561-rv5j1201	1530	23	.	.	.
cord-022561-rv5j1201	1531	1	Microscopically	microscopically	RB
cord-022561-rv5j1201	1531	2	,	,	,
cord-022561-rv5j1201	1531	3	the	the	DT
cord-022561-rv5j1201	1531	4	bone	bone	NN
cord-022561-rv5j1201	1531	5	marrow	marrow	NN
cord-022561-rv5j1201	1531	6	is	be	VBZ
cord-022561-rv5j1201	1531	7	hypocellular	hypocellular	NNP
cord-022561-rv5j1201	1531	8	,	,	,
cord-022561-rv5j1201	1531	9	normocellular	normocellular	NNP
cord-022561-rv5j1201	1531	10	,	,	,
cord-022561-rv5j1201	1531	11	or	or	CC
cord-022561-rv5j1201	1531	12	hypercellular	hypercellular	NNP
cord-022561-rv5j1201	1531	13	.	.	.
cord-022561-rv5j1201	1532	1	There	there	EX
cord-022561-rv5j1201	1532	2	may	may	MD
cord-022561-rv5j1201	1532	3	be	be	VB
cord-022561-rv5j1201	1532	4	erythroid	erythroid	JJ
cord-022561-rv5j1201	1532	5	hypoplasia	hypoplasia	NN
cord-022561-rv5j1201	1532	6	,	,	,
cord-022561-rv5j1201	1532	7	erythroid	erythroid	JJ
cord-022561-rv5j1201	1532	8	hyperplasia	hyperplasia	NN
cord-022561-rv5j1201	1532	9	with	with	IN
cord-022561-rv5j1201	1532	10	maturation	maturation	NN
cord-022561-rv5j1201	1532	11	arrest	arrest	NN
cord-022561-rv5j1201	1532	12	,	,	,
cord-022561-rv5j1201	1532	13	or	or	CC
cord-022561-rv5j1201	1532	14	acute	acute	JJ
cord-022561-rv5j1201	1532	15	leukemia	leukemia	NN
cord-022561-rv5j1201	1532	16	.	.	.
cord-022561-rv5j1201	1533	1	Feline	Feline	NNP
cord-022561-rv5j1201	1533	2	Immunodeficiency	Immunodeficiency	NNP
cord-022561-rv5j1201	1533	3	Virus	Virus	NNP
cord-022561-rv5j1201	1533	4	.	.	.
cord-022561-rv5j1201	1534	1	Feline	feline	JJ
cord-022561-rv5j1201	1534	2	immunodeficiency	immunodeficiency	NN
cord-022561-rv5j1201	1534	3	virus	virus	NN
cord-022561-rv5j1201	1534	4	(	(	-LRB-
cord-022561-rv5j1201	1534	5	FIV	FIV	NNP
cord-022561-rv5j1201	1534	6	)	)	-RRB-
cord-022561-rv5j1201	1534	7	,	,	,
cord-022561-rv5j1201	1534	8	another	another	DT
cord-022561-rv5j1201	1534	9	feline	feline	JJ
cord-022561-rv5j1201	1534	10	lentivirus	lentivirus	NN
cord-022561-rv5j1201	1534	11	,	,	,
cord-022561-rv5j1201	1534	12	causes	cause	VBZ
cord-022561-rv5j1201	1534	13	anemia	anemia	NN
cord-022561-rv5j1201	1534	14	in	in	IN
cord-022561-rv5j1201	1534	15	a	a	DT
cord-022561-rv5j1201	1534	16	minority	minority	NN
cord-022561-rv5j1201	1534	17	of	of	IN
cord-022561-rv5j1201	1534	18	infected	infected	JJ
cord-022561-rv5j1201	1534	19	cats	cat	NNS
cord-022561-rv5j1201	1534	20	.	.	.
cord-022561-rv5j1201	1535	1	Immunosuppressive	immunosuppressive	JJ
cord-022561-rv5j1201	1535	2	effects	effect	NNS
cord-022561-rv5j1201	1535	3	of	of	IN
cord-022561-rv5j1201	1535	4	FIV	fiv	NN
cord-022561-rv5j1201	1535	5	from	from	IN
cord-022561-rv5j1201	1535	6	thymic	thymic	JJ
cord-022561-rv5j1201	1535	7	depletion	depletion	NN
cord-022561-rv5j1201	1535	8	are	be	VBP
cord-022561-rv5j1201	1535	9	discussed	discuss	VBN
cord-022561-rv5j1201	1535	10	elsewhere	elsewhere	RB
cord-022561-rv5j1201	1535	11	.	.	.
cord-022561-rv5j1201	1536	1	It	-PRON-	PRP
cord-022561-rv5j1201	1536	2	is	be	VBZ
cord-022561-rv5j1201	1536	3	generally	generally	RB
cord-022561-rv5j1201	1536	4	accepted	accept	VBN
cord-022561-rv5j1201	1536	5	that	that	IN
cord-022561-rv5j1201	1536	6	anemia	anemia	NN
cord-022561-rv5j1201	1536	7	does	do	VBZ
cord-022561-rv5j1201	1536	8	not	not	RB
cord-022561-rv5j1201	1536	9	result	result	VB
cord-022561-rv5j1201	1536	10	directly	directly	RB
cord-022561-rv5j1201	1536	11	from	from	IN
cord-022561-rv5j1201	1536	12	FIV	fiv	NN
cord-022561-rv5j1201	1536	13	infection	infection	NN
cord-022561-rv5j1201	1536	14	but	but	CC
cord-022561-rv5j1201	1536	15	instead	instead	RB
cord-022561-rv5j1201	1536	16	develops	develop	VBZ
cord-022561-rv5j1201	1536	17	because	because	IN
cord-022561-rv5j1201	1536	18	of	of	IN
cord-022561-rv5j1201	1536	19	concurrent	concurrent	JJ
cord-022561-rv5j1201	1536	20	disease	disease	NN
cord-022561-rv5j1201	1536	21	such	such	JJ
cord-022561-rv5j1201	1536	22	as	as	IN
cord-022561-rv5j1201	1536	23	coinfection	coinfection	NN
cord-022561-rv5j1201	1536	24	with	with	IN
cord-022561-rv5j1201	1536	25	FeLV	FeLV	NNP
cord-022561-rv5j1201	1536	26	or	or	CC
cord-022561-rv5j1201	1536	27	hemotropic	hemotropic	NNP
cord-022561-rv5j1201	1536	28	mycoplasma	mycoplasma	NN
cord-022561-rv5j1201	1536	29	,	,	,
cord-022561-rv5j1201	1536	30	other	other	JJ
cord-022561-rv5j1201	1536	31	infection	infection	NN
cord-022561-rv5j1201	1536	32	,	,	,
cord-022561-rv5j1201	1536	33	or	or	CC
cord-022561-rv5j1201	1536	34	malignancy	malignancy	NN
cord-022561-rv5j1201	1536	35	.	.	.
cord-022561-rv5j1201	1537	1	The	the	DT
cord-022561-rv5j1201	1537	2	severity	severity	NN
cord-022561-rv5j1201	1537	3	and	and	CC
cord-022561-rv5j1201	1537	4	type	type	NN
cord-022561-rv5j1201	1537	5	of	of	IN
cord-022561-rv5j1201	1537	6	anemia	anemia	NN
cord-022561-rv5j1201	1537	7	in	in	IN
cord-022561-rv5j1201	1537	8	FIV	FIV	NNP
cord-022561-rv5j1201	1537	9	-	-	HYPH
cord-022561-rv5j1201	1537	10	infected	infect	VBN
cord-022561-rv5j1201	1537	11	cats	cat	NNS
cord-022561-rv5j1201	1537	12	depends	depend	VBZ
cord-022561-rv5j1201	1537	13	on	on	IN
cord-022561-rv5j1201	1537	14	the	the	DT
cord-022561-rv5j1201	1537	15	other	other	JJ
cord-022561-rv5j1201	1537	16	specific	specific	JJ
cord-022561-rv5j1201	1537	17	disease	disease	NN
cord-022561-rv5j1201	1537	18	processes	process	NNS
cord-022561-rv5j1201	1537	19	involved	involve	VBN
cord-022561-rv5j1201	1537	20	.	.	.
cord-022561-rv5j1201	1538	1	The	the	DT
cord-022561-rv5j1201	1538	2	thymus	thymus	NN
cord-022561-rv5j1201	1538	3	,	,	,
cord-022561-rv5j1201	1538	4	spleen	spleen	NNS
cord-022561-rv5j1201	1538	5	,	,	,
cord-022561-rv5j1201	1538	6	lymph	lymph	NN
cord-022561-rv5j1201	1538	7	nodes	node	NNS
cord-022561-rv5j1201	1538	8	,	,	,
cord-022561-rv5j1201	1538	9	and	and	CC
cord-022561-rv5j1201	1538	10	lymph	lymph	NN
cord-022561-rv5j1201	1538	11	nodules	nodule	NNS
cord-022561-rv5j1201	1538	12	,	,	,
cord-022561-rv5j1201	1538	13	including	include	VBG
cord-022561-rv5j1201	1538	14	MALT	malt	NN
cord-022561-rv5j1201	1538	15	,	,	,
cord-022561-rv5j1201	1538	16	are	be	VBP
cord-022561-rv5j1201	1538	17	classified	classify	VBN
cord-022561-rv5j1201	1538	18	as	as	IN
cord-022561-rv5j1201	1538	19	part	part	NN
cord-022561-rv5j1201	1538	20	of	of	IN
cord-022561-rv5j1201	1538	21	both	both	CC
cord-022561-rv5j1201	1538	22	the	the	DT
cord-022561-rv5j1201	1538	23	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	1538	24	and	and	CC
cord-022561-rv5j1201	1538	25	immune	immune	JJ
cord-022561-rv5j1201	1538	26	systems	system	NNS
cord-022561-rv5j1201	1538	27	.	.	.
cord-022561-rv5j1201	1539	1	The	the	DT
cord-022561-rv5j1201	1539	2	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	1539	3	system	system	NN
cord-022561-rv5j1201	1539	4	(	(	-LRB-
cord-022561-rv5j1201	1539	5	also	also	RB
cord-022561-rv5j1201	1539	6	known	know	VBN
cord-022561-rv5j1201	1539	7	as	as	IN
cord-022561-rv5j1201	1539	8	lymphatic	lymphatic	JJ
cord-022561-rv5j1201	1539	9	system	system	NN
cord-022561-rv5j1201	1539	10	in	in	IN
cord-022561-rv5j1201	1539	11	some	some	DT
cord-022561-rv5j1201	1539	12	texts	text	NNS
cord-022561-rv5j1201	1539	13	)	)	-RRB-
cord-022561-rv5j1201	1539	14	is	be	VBZ
cord-022561-rv5j1201	1539	15	broadly	broadly	RB
cord-022561-rv5j1201	1539	16	categorized	categorize	VBN
cord-022561-rv5j1201	1539	17	into	into	IN
cord-022561-rv5j1201	1539	18	primary	primary	JJ
cord-022561-rv5j1201	1539	19	and	and	CC
cord-022561-rv5j1201	1539	20	secondary	secondary	JJ
cord-022561-rv5j1201	1539	21	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	1539	22	organs	organ	NNS
cord-022561-rv5j1201	1539	23	.	.	.
cord-022561-rv5j1201	1540	1	The	the	DT
cord-022561-rv5j1201	1540	2	main	main	JJ
cord-022561-rv5j1201	1540	3	primary	primary	JJ
cord-022561-rv5j1201	1540	4	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	1540	5	organs	organ	NNS
cord-022561-rv5j1201	1540	6	include	include	VBP
cord-022561-rv5j1201	1540	7	thymus	thymus	NN
cord-022561-rv5j1201	1540	8	,	,	,
cord-022561-rv5j1201	1540	9	bone	bone	NN
cord-022561-rv5j1201	1540	10	marrow	marrow	NN
cord-022561-rv5j1201	1540	11	,	,	,
cord-022561-rv5j1201	1540	12	and	and	CC
cord-022561-rv5j1201	1540	13	bursa	bursa	NN
cord-022561-rv5j1201	1540	14	of	of	IN
cord-022561-rv5j1201	1540	15	Fabricius	Fabricius	NNP
cord-022561-rv5j1201	1540	16	in	in	IN
cord-022561-rv5j1201	1540	17	birds	bird	NNS
cord-022561-rv5j1201	1540	18	and	and	CC
cord-022561-rv5j1201	1540	19	are	be	VBP
cord-022561-rv5j1201	1540	20	the	the	DT
cord-022561-rv5j1201	1540	21	sites	site	NNS
cord-022561-rv5j1201	1540	22	at	at	IN
cord-022561-rv5j1201	1540	23	761.e1	761.e1	CD
cord-022561-rv5j1201	1540	24	CHAPTER	chapter	NN
cord-022561-rv5j1201	1540	25	13	13	CD
cord-022561-rv5j1201	1540	26	Bone	Bone	NNP
cord-022561-rv5j1201	1540	27	Marrow	Marrow	NNP
cord-022561-rv5j1201	1540	28	,	,	,
cord-022561-rv5j1201	1540	29	Blood	blood	NN
cord-022561-rv5j1201	1540	30	Cells	cell	NNS
cord-022561-rv5j1201	1540	31	,	,	,
cord-022561-rv5j1201	1540	32	and	and	CC
cord-022561-rv5j1201	1540	33	the	the	DT
cord-022561-rv5j1201	1540	34	Lymphoid	Lymphoid	NNP
cord-022561-rv5j1201	1540	35	/	/	SYM
cord-022561-rv5j1201	1540	36	Lymphatic	Lymphatic	NNP
cord-022561-rv5j1201	1540	37	System	System	NNP
cord-022561-rv5j1201	1541	1	Because	because	IN
cord-022561-rv5j1201	1541	2	the	the	DT
cord-022561-rv5j1201	1541	3	thymus	thymus	NN
cord-022561-rv5j1201	1541	4	involutes	involute	NNS
cord-022561-rv5j1201	1541	5	after	after	IN
cord-022561-rv5j1201	1541	6	sexual	sexual	JJ
cord-022561-rv5j1201	1541	7	maturity	maturity	NN
cord-022561-rv5j1201	1541	8	,	,	,
cord-022561-rv5j1201	1541	9	evaluation	evaluation	NN
cord-022561-rv5j1201	1541	10	of	of	IN
cord-022561-rv5j1201	1541	11	whether	whether	IN
cord-022561-rv5j1201	1541	12	it	-PRON-	PRP
cord-022561-rv5j1201	1541	13	is	be	VBZ
cord-022561-rv5j1201	1541	14	smaller	small	JJR
cord-022561-rv5j1201	1541	15	than	than	IN
cord-022561-rv5j1201	1541	16	normal	normal	JJ
cord-022561-rv5j1201	1541	17	is	be	VBZ
cord-022561-rv5j1201	1541	18	difficult	difficult	JJ
cord-022561-rv5j1201	1541	19	to	to	TO
cord-022561-rv5j1201	1541	20	discern	discern	VB
cord-022561-rv5j1201	1541	21	unless	unless	IN
cord-022561-rv5j1201	1541	22	the	the	DT
cord-022561-rv5j1201	1541	23	change	change	NN
cord-022561-rv5j1201	1541	24	is	be	VBZ
cord-022561-rv5j1201	1541	25	extreme	extreme	JJ
cord-022561-rv5j1201	1541	26	or	or	CC
cord-022561-rv5j1201	1541	27	age	age	NN
cord-022561-rv5j1201	1541	28	-	-	HYPH
cord-022561-rv5j1201	1541	29	matched	match	VBN
cord-022561-rv5j1201	1541	30	control	control	NN
cord-022561-rv5j1201	1541	31	animals	animal	NNS
cord-022561-rv5j1201	1541	32	are	be	VBP
cord-022561-rv5j1201	1541	33	available	available	JJ
cord-022561-rv5j1201	1541	34	.	.	.
cord-022561-rv5j1201	1542	1	Before	before	IN
cord-022561-rv5j1201	1542	2	sexual	sexual	JJ
cord-022561-rv5j1201	1542	3	maturity	maturity	NN
cord-022561-rv5j1201	1542	4	the	the	DT
cord-022561-rv5j1201	1542	5	thymus	thymus	NN
cord-022561-rv5j1201	1542	6	is	be	VBZ
cord-022561-rv5j1201	1542	7	easily	easily	RB
cord-022561-rv5j1201	1542	8	identified	identify	VBN
cord-022561-rv5j1201	1542	9	as	as	IN
cord-022561-rv5j1201	1542	10	a	a	DT
cord-022561-rv5j1201	1542	11	lobular	lobular	JJ
cord-022561-rv5j1201	1542	12	white	white	NN
cord-022561-rv5j1201	1542	13	to	to	IN
cord-022561-rv5j1201	1542	14	gray	gray	JJ
cord-022561-rv5j1201	1542	15	organ	organ	NN
cord-022561-rv5j1201	1542	16	with	with	IN
cord-022561-rv5j1201	1542	17	a	a	DT
cord-022561-rv5j1201	1542	18	thin	thin	JJ
cord-022561-rv5j1201	1542	19	capsule	capsule	NN
cord-022561-rv5j1201	1542	20	.	.	.
cord-022561-rv5j1201	1543	1	After	after	IN
cord-022561-rv5j1201	1543	2	sexual	sexual	JJ
cord-022561-rv5j1201	1543	3	maturity	maturity	NN
cord-022561-rv5j1201	1543	4	the	the	DT
cord-022561-rv5j1201	1543	5	gland	gland	NN
cord-022561-rv5j1201	1543	6	is	be	VBZ
cord-022561-rv5j1201	1543	7	often	often	RB
cord-022561-rv5j1201	1543	8	grossly	grossly	RB
cord-022561-rv5j1201	1543	9	indistinguishable	indistinguishable	JJ
cord-022561-rv5j1201	1543	10	from	from	IN
cord-022561-rv5j1201	1543	11	adipose	adipose	JJ
cord-022561-rv5j1201	1543	12	connective	connective	JJ
cord-022561-rv5j1201	1543	13	tissue	tissue	NN
cord-022561-rv5j1201	1543	14	within	within	IN
cord-022561-rv5j1201	1543	15	the	the	DT
cord-022561-rv5j1201	1543	16	cranial	cranial	JJ
cord-022561-rv5j1201	1543	17	mediastinum	mediastinum	NN
cord-022561-rv5j1201	1543	18	,	,	,
cord-022561-rv5j1201	1543	19	although	although	IN
cord-022561-rv5j1201	1543	20	microscopic	microscopic	JJ
cord-022561-rv5j1201	1543	21	remnants	remnant	NNS
cord-022561-rv5j1201	1543	22	may	may	MD
cord-022561-rv5j1201	1543	23	remain	remain	VB
cord-022561-rv5j1201	1543	24	.	.	.
cord-022561-rv5j1201	1544	1	An	an	DT
cord-022561-rv5j1201	1544	2	extremely	extremely	RB
cord-022561-rv5j1201	1544	3	small	small	JJ
cord-022561-rv5j1201	1544	4	thymus	thymus	NN
cord-022561-rv5j1201	1544	5	in	in	IN
cord-022561-rv5j1201	1544	6	a	a	DT
cord-022561-rv5j1201	1544	7	neonatal	neonatal	JJ
cord-022561-rv5j1201	1544	8	animal	animal	NN
cord-022561-rv5j1201	1544	9	should	should	MD
cord-022561-rv5j1201	1544	10	be	be	VB
cord-022561-rv5j1201	1544	11	considered	consider	VBN
cord-022561-rv5j1201	1544	12	abnormal	abnormal	JJ
cord-022561-rv5j1201	1544	13	and	and	CC
cord-022561-rv5j1201	1544	14	may	may	MD
cord-022561-rv5j1201	1544	15	indicate	indicate	VB
cord-022561-rv5j1201	1544	16	a	a	DT
cord-022561-rv5j1201	1544	17	primary	primary	JJ
cord-022561-rv5j1201	1544	18	immunodeficiency	immunodeficiency	NN
cord-022561-rv5j1201	1544	19	or	or	CC
cord-022561-rv5j1201	1544	20	secondary	secondary	JJ
cord-022561-rv5j1201	1544	21	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	1544	22	depletion	depletion	NN
cord-022561-rv5j1201	1544	23	caused	cause	VBN
cord-022561-rv5j1201	1544	24	by	by	IN
cord-022561-rv5j1201	1544	25	extreme	extreme	JJ
cord-022561-rv5j1201	1544	26	stress	stress	NN
cord-022561-rv5j1201	1544	27	,	,	,
cord-022561-rv5j1201	1544	28	often	often	RB
cord-022561-rv5j1201	1544	29	due	due	JJ
cord-022561-rv5j1201	1544	30	to	to	IN
cord-022561-rv5j1201	1544	31	infectious	infectious	JJ
cord-022561-rv5j1201	1544	32	diseases	disease	NNS
cord-022561-rv5j1201	1544	33	.	.	.
cord-022561-rv5j1201	1545	1	Enlargement	enlargement	NN
cord-022561-rv5j1201	1545	2	of	of	IN
cord-022561-rv5j1201	1545	3	the	the	DT
cord-022561-rv5j1201	1545	4	thymus	thymus	NN
cord-022561-rv5j1201	1545	5	is	be	VBZ
cord-022561-rv5j1201	1545	6	most	most	RBS
cord-022561-rv5j1201	1545	7	often	often	RB
cord-022561-rv5j1201	1545	8	due	due	JJ
cord-022561-rv5j1201	1545	9	to	to	IN
cord-022561-rv5j1201	1545	10	neoplasia	neoplasia	NN
cord-022561-rv5j1201	1545	11	.	.	.
cord-022561-rv5j1201	1546	1	Serial	serial	JJ
cord-022561-rv5j1201	1546	2	sectioning	sectioning	NN
cord-022561-rv5j1201	1546	3	of	of	IN
cord-022561-rv5j1201	1546	4	the	the	DT
cord-022561-rv5j1201	1546	5	thymus	thymus	NN
cord-022561-rv5j1201	1546	6	allows	allow	VBZ
cord-022561-rv5j1201	1546	7	for	for	IN
cord-022561-rv5j1201	1546	8	gross	gross	JJ
cord-022561-rv5j1201	1546	9	identification	identification	NN
cord-022561-rv5j1201	1546	10	of	of	IN
cord-022561-rv5j1201	1546	11	neoplasms	neoplasm	NNS
cord-022561-rv5j1201	1546	12	,	,	,
cord-022561-rv5j1201	1546	13	cysts	cyst	NNS
cord-022561-rv5j1201	1546	14	,	,	,
cord-022561-rv5j1201	1546	15	or	or	CC
cord-022561-rv5j1201	1546	16	hematomas	hematoma	NNS
cord-022561-rv5j1201	1546	17	.	.	.
cord-022561-rv5j1201	1547	1	Spleens	spleen	NNS
cord-022561-rv5j1201	1547	2	vary	vary	VBP
cord-022561-rv5j1201	1547	3	in	in	IN
cord-022561-rv5j1201	1547	4	size	size	NN
cord-022561-rv5j1201	1547	5	within	within	IN
cord-022561-rv5j1201	1547	6	the	the	DT
cord-022561-rv5j1201	1547	7	same	same	JJ
cord-022561-rv5j1201	1547	8	species	specie	NNS
cord-022561-rv5j1201	1547	9	and	and	CC
cord-022561-rv5j1201	1547	10	among	among	IN
cord-022561-rv5j1201	1547	11	the	the	DT
cord-022561-rv5j1201	1547	12	different	different	JJ
cord-022561-rv5j1201	1547	13	species	specie	NNS
cord-022561-rv5j1201	1547	14	of	of	IN
cord-022561-rv5j1201	1547	15	domestic	domestic	JJ
cord-022561-rv5j1201	1547	16	animals	animal	NNS
cord-022561-rv5j1201	1547	17	.	.	.
cord-022561-rv5j1201	1548	1	The	the	DT
cord-022561-rv5j1201	1548	2	spleen	spleen	NN
cord-022561-rv5j1201	1548	3	can	can	MD
cord-022561-rv5j1201	1548	4	be	be	VB
cord-022561-rv5j1201	1548	5	enlarged	enlarge	VBN
cord-022561-rv5j1201	1548	6	(	(	-LRB-
cord-022561-rv5j1201	1548	7	splenomegaly	splenomegaly	NN
cord-022561-rv5j1201	1548	8	)	)	-RRB-
cord-022561-rv5j1201	1548	9	,	,	,
cord-022561-rv5j1201	1548	10	normal	normal	JJ
cord-022561-rv5j1201	1548	11	in	in	IN
cord-022561-rv5j1201	1548	12	size	size	NN
cord-022561-rv5j1201	1548	13	,	,	,
cord-022561-rv5j1201	1548	14	or	or	CC
cord-022561-rv5j1201	1548	15	small	small	JJ
cord-022561-rv5j1201	1548	16	(	(	-LRB-
cord-022561-rv5j1201	1548	17	atrophy	atrophy	NN
cord-022561-rv5j1201	1548	18	)	)	-RRB-
cord-022561-rv5j1201	1548	19	,	,	,
cord-022561-rv5j1201	1548	20	and	and	CC
cord-022561-rv5j1201	1548	21	the	the	DT
cord-022561-rv5j1201	1548	22	surface	surface	NN
cord-022561-rv5j1201	1548	23	can	can	MD
cord-022561-rv5j1201	1548	24	be	be	VB
cord-022561-rv5j1201	1548	25	smooth	smooth	JJ
cord-022561-rv5j1201	1548	26	,	,	,
cord-022561-rv5j1201	1548	27	wrinkled	wrinkled	JJ
cord-022561-rv5j1201	1548	28	,	,	,
cord-022561-rv5j1201	1548	29	or	or	CC
cord-022561-rv5j1201	1548	30	nodular	nodular	JJ
cord-022561-rv5j1201	1548	31	.	.	.
cord-022561-rv5j1201	1549	1	The	the	DT
cord-022561-rv5j1201	1549	2	appearance	appearance	NN
cord-022561-rv5j1201	1549	3	of	of	IN
cord-022561-rv5j1201	1549	4	the	the	DT
cord-022561-rv5j1201	1549	5	cut	cut	NN
cord-022561-rv5j1201	1549	6	surface	surface	NN
cord-022561-rv5j1201	1549	7	of	of	IN
cord-022561-rv5j1201	1549	8	the	the	DT
cord-022561-rv5j1201	1549	9	spleen	spleen	NNS
cord-022561-rv5j1201	1549	10	in	in	IN
cord-022561-rv5j1201	1549	11	normal	normal	JJ
cord-022561-rv5j1201	1549	12	animals	animal	NNS
cord-022561-rv5j1201	1549	13	depends	depend	VBZ
cord-022561-rv5j1201	1549	14	on	on	IN
cord-022561-rv5j1201	1549	15	the	the	DT
cord-022561-rv5j1201	1549	16	amount	amount	NN
cord-022561-rv5j1201	1549	17	of	of	IN
cord-022561-rv5j1201	1549	18	stroma	stroma	NN
cord-022561-rv5j1201	1549	19	(	(	-LRB-
cord-022561-rv5j1201	1549	20	e.g.	e.g.	RB
cord-022561-rv5j1201	1549	21	,	,	,
cord-022561-rv5j1201	1549	22	trabeculae	trabeculae	NNP
cord-022561-rv5j1201	1549	23	are	be	VBP
cord-022561-rv5j1201	1549	24	prominent	prominent	JJ
cord-022561-rv5j1201	1549	25	in	in	IN
cord-022561-rv5j1201	1549	26	ruminants	ruminant	NNS
cord-022561-rv5j1201	1549	27	)	)	-RRB-
cord-022561-rv5j1201	1549	28	;	;	:
cord-022561-rv5j1201	1549	29	the	the	DT
cord-022561-rv5j1201	1549	30	size	size	NN
cord-022561-rv5j1201	1549	31	and	and	CC
cord-022561-rv5j1201	1549	32	visibility	visibility	NN
cord-022561-rv5j1201	1549	33	of	of	IN
cord-022561-rv5j1201	1549	34	the	the	DT
cord-022561-rv5j1201	1549	35	white	white	JJ
cord-022561-rv5j1201	1549	36	pulp	pulp	NN
cord-022561-rv5j1201	1549	37	,	,	,
cord-022561-rv5j1201	1549	38	which	which	WDT
cord-022561-rv5j1201	1549	39	reflects	reflect	VBZ
cord-022561-rv5j1201	1549	40	the	the	DT
cord-022561-rv5j1201	1549	41	amount	amount	NN
cord-022561-rv5j1201	1549	42	of	of	IN
cord-022561-rv5j1201	1549	43	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	1549	44	tissue	tissue	NN
cord-022561-rv5j1201	1549	45	;	;	:
cord-022561-rv5j1201	1549	46	and	and	CC
cord-022561-rv5j1201	1549	47	whether	whether	IN
cord-022561-rv5j1201	1549	48	the	the	DT
cord-022561-rv5j1201	1549	49	red	red	JJ
cord-022561-rv5j1201	1549	50	pulp	pulp	NN
cord-022561-rv5j1201	1549	51	is	be	VBZ
cord-022561-rv5j1201	1549	52	congested	congest	VBN
cord-022561-rv5j1201	1549	53	with	with	IN
cord-022561-rv5j1201	1549	54	blood	blood	NN
cord-022561-rv5j1201	1549	55	.	.	.
cord-022561-rv5j1201	1550	1	During	during	IN
cord-022561-rv5j1201	1550	2	an	an	DT
cord-022561-rv5j1201	1550	3	autopsy	autopsy	JJ
cord-022561-rv5j1201	1550	4	(	(	-LRB-
cord-022561-rv5j1201	1550	5	syn	syn	NN
cord-022561-rv5j1201	1550	6	:	:	:
cord-022561-rv5j1201	1550	7	necropsy	necropsy	JJ
cord-022561-rv5j1201	1550	8	)	)	-RRB-
cord-022561-rv5j1201	1550	9	,	,	,
cord-022561-rv5j1201	1550	10	the	the	DT
cord-022561-rv5j1201	1550	11	spleen	spleen	NN
cord-022561-rv5j1201	1550	12	is	be	VBZ
cord-022561-rv5j1201	1550	13	dissected	dissect	VBN
cord-022561-rv5j1201	1550	14	free	free	JJ
cord-022561-rv5j1201	1550	15	and	and	CC
cord-022561-rv5j1201	1550	16	checked	check	VBN
cord-022561-rv5j1201	1550	17	for	for	IN
cord-022561-rv5j1201	1550	18	torsion	torsion	NN
cord-022561-rv5j1201	1550	19	of	of	IN
cord-022561-rv5j1201	1550	20	the	the	DT
cord-022561-rv5j1201	1550	21	gastrosplenic	gastrosplenic	NNP
cord-022561-rv5j1201	1550	22	ligament	ligament	NN
cord-022561-rv5j1201	1550	23	(	(	-LRB-
cord-022561-rv5j1201	1550	24	in	in	IN
cord-022561-rv5j1201	1550	25	nonruminants	nonruminant	NNS
cord-022561-rv5j1201	1550	26	)	)	-RRB-
cord-022561-rv5j1201	1550	27	.	.	.
cord-022561-rv5j1201	1551	1	The	the	DT
cord-022561-rv5j1201	1551	2	spleen	spleen	NN
cord-022561-rv5j1201	1551	3	is	be	VBZ
cord-022561-rv5j1201	1551	4	then	then	RB
cord-022561-rv5j1201	1551	5	sliced	slice	VBN
cord-022561-rv5j1201	1551	6	transversely	transversely	RB
cord-022561-rv5j1201	1551	7	at	at	IN
cord-022561-rv5j1201	1551	8	approximately	approximately	RB
cord-022561-rv5j1201	1551	9	5-mm	5-mm	CD
cord-022561-rv5j1201	1551	10	intervals	interval	NNS
cord-022561-rv5j1201	1551	11	(	(	-LRB-
cord-022561-rv5j1201	1551	12	serial	serial	JJ
cord-022561-rv5j1201	1551	13	sectioning	sectioning	NN
cord-022561-rv5j1201	1551	14	)	)	-RRB-
cord-022561-rv5j1201	1551	15	,	,	,
cord-022561-rv5j1201	1551	16	and	and	CC
cord-022561-rv5j1201	1551	17	the	the	DT
cord-022561-rv5j1201	1551	18	cut	cut	NN
cord-022561-rv5j1201	1551	19	surfaces	surface	NNS
cord-022561-rv5j1201	1551	20	are	be	VBP
cord-022561-rv5j1201	1551	21	checked	check	VBN
cord-022561-rv5j1201	1551	22	for	for	IN
cord-022561-rv5j1201	1551	23	lesions	lesion	NNS
cord-022561-rv5j1201	1551	24	.	.	.
cord-022561-rv5j1201	1552	1	Specimens	specimen	NNS
cord-022561-rv5j1201	1552	2	are	be	VBP
cord-022561-rv5j1201	1552	3	taken	take	VBN
cord-022561-rv5j1201	1552	4	for	for	IN
cord-022561-rv5j1201	1552	5	tests	test	NNS
cord-022561-rv5j1201	1552	6	that	that	WDT
cord-022561-rv5j1201	1552	7	require	require	VBP
cord-022561-rv5j1201	1552	8	fresh	fresh	JJ
cord-022561-rv5j1201	1552	9	tissue	tissue	NN
cord-022561-rv5j1201	1552	10	(	(	-LRB-
cord-022561-rv5j1201	1552	11	e.g.	e.g.	RB
cord-022561-rv5j1201	1552	12	,	,	,
cord-022561-rv5j1201	1552	13	bacteriologic	bacteriologic	NNP
cord-022561-rv5j1201	1552	14	and	and	CC
cord-022561-rv5j1201	1552	15	virologic	virologic	JJ
cord-022561-rv5j1201	1552	16	examinations	examination	NNS
cord-022561-rv5j1201	1552	17	)	)	-RRB-
cord-022561-rv5j1201	1552	18	,	,	,
cord-022561-rv5j1201	1552	19	and	and	CC
cord-022561-rv5j1201	1552	20	the	the	DT
cord-022561-rv5j1201	1552	21	remaining	remain	VBG
cord-022561-rv5j1201	1552	22	cross	cross	NN
cord-022561-rv5j1201	1552	23	-	-	NNS
cord-022561-rv5j1201	1552	24	sections	section	NNS
cord-022561-rv5j1201	1552	25	are	be	VBP
cord-022561-rv5j1201	1552	26	placed	place	VBN
cord-022561-rv5j1201	1552	27	in	in	IN
cord-022561-rv5j1201	1552	28	fixative	fixative	NN
cord-022561-rv5j1201	1552	29	(	(	-LRB-
cord-022561-rv5j1201	1552	30	10	10	CD
cord-022561-rv5j1201	1552	31	%	%	NN
cord-022561-rv5j1201	1552	32	buffered	buffer	VBN
cord-022561-rv5j1201	1552	33	neutral	neutral	JJ
cord-022561-rv5j1201	1552	34	formalin	formalin	NN
cord-022561-rv5j1201	1552	35	)	)	-RRB-
cord-022561-rv5j1201	1552	36	.	.	.
cord-022561-rv5j1201	1553	1	A	a	DT
cord-022561-rv5j1201	1553	2	diffusely	diffusely	RB
cord-022561-rv5j1201	1553	3	enlarged	enlarge	VBN
cord-022561-rv5j1201	1553	4	spleen	spleen	NNS
cord-022561-rv5j1201	1553	5	should	should	MD
cord-022561-rv5j1201	1553	6	be	be	VB
cord-022561-rv5j1201	1553	7	serially	serially	RB
cord-022561-rv5j1201	1553	8	sectioned	section	VBN
cord-022561-rv5j1201	1553	9	to	to	TO
cord-022561-rv5j1201	1553	10	determine	determine	VB
cord-022561-rv5j1201	1553	11	if	if	IN
cord-022561-rv5j1201	1553	12	the	the	DT
cord-022561-rv5j1201	1553	13	splenomegaly	splenomegaly	NN
cord-022561-rv5j1201	1553	14	is	be	VBZ
cord-022561-rv5j1201	1553	15	due	due	JJ
cord-022561-rv5j1201	1553	16	to	to	IN
cord-022561-rv5j1201	1553	17	congestion	congestion	NN
cord-022561-rv5j1201	1553	18	.	.	.
cord-022561-rv5j1201	1554	1	The	the	DT
cord-022561-rv5j1201	1554	2	cut	cut	NN
cord-022561-rv5j1201	1554	3	surface	surface	NN
cord-022561-rv5j1201	1554	4	of	of	IN
cord-022561-rv5j1201	1554	5	severely	severely	RB
cord-022561-rv5j1201	1554	6	congested	congest	VBN
cord-022561-rv5j1201	1554	7	spleens	spleen	NNS
cord-022561-rv5j1201	1554	8	is	be	VBZ
cord-022561-rv5j1201	1554	9	red	red	JJ
cord-022561-rv5j1201	1554	10	to	to	IN
cord-022561-rv5j1201	1554	11	bluish	bluish	JJ
cord-022561-rv5j1201	1554	12	-	-	HYPH
cord-022561-rv5j1201	1554	13	black	black	JJ
cord-022561-rv5j1201	1554	14	and	and	CC
cord-022561-rv5j1201	1554	15	exudes	exude	VBZ
cord-022561-rv5j1201	1554	16	blood	blood	NN
cord-022561-rv5j1201	1554	17	(	(	-LRB-
cord-022561-rv5j1201	1554	18	bloody	bloody	JJ
cord-022561-rv5j1201	1554	19	spleens	spleen	NNS
cord-022561-rv5j1201	1554	20	)	)	-RRB-
cord-022561-rv5j1201	1554	21	,	,	,
cord-022561-rv5j1201	1554	22	whereas	whereas	IN
cord-022561-rv5j1201	1554	23	cut	cut	VBN
cord-022561-rv5j1201	1554	24	surfaces	surface	NNS
cord-022561-rv5j1201	1554	25	of	of	IN
cord-022561-rv5j1201	1554	26	noncongested	noncongested	JJ
cord-022561-rv5j1201	1554	27	enlarged	enlarged	JJ
cord-022561-rv5j1201	1554	28	spleens	spleen	NNS
cord-022561-rv5j1201	1554	29	ooze	ooze	VBP
cord-022561-rv5j1201	1554	30	little	little	JJ
cord-022561-rv5j1201	1554	31	blood	blood	NN
cord-022561-rv5j1201	1554	32	(	(	-LRB-
cord-022561-rv5j1201	1554	33	meaty	meaty	JJ
cord-022561-rv5j1201	1554	34	spleens	spleen	NNS
cord-022561-rv5j1201	1554	35	)	)	-RRB-
cord-022561-rv5j1201	1554	36	and	and	CC
cord-022561-rv5j1201	1554	37	the	the	DT
cord-022561-rv5j1201	1554	38	color	color	NN
cord-022561-rv5j1201	1554	39	depends	depend	VBZ
cord-022561-rv5j1201	1554	40	on	on	IN
cord-022561-rv5j1201	1554	41	how	how	WRB
cord-022561-rv5j1201	1554	42	much	much	JJ
cord-022561-rv5j1201	1554	43	of	of	IN
cord-022561-rv5j1201	1554	44	the	the	DT
cord-022561-rv5j1201	1554	45	normal	normal	JJ
cord-022561-rv5j1201	1554	46	parenchyma	parenchyma	NN
cord-022561-rv5j1201	1554	47	is	be	VBZ
cord-022561-rv5j1201	1554	48	replaced	replace	VBN
cord-022561-rv5j1201	1554	49	by	by	IN
cord-022561-rv5j1201	1554	50	inflammatory	inflammatory	JJ
cord-022561-rv5j1201	1554	51	cells	cell	NNS
cord-022561-rv5j1201	1554	52	,	,	,
cord-022561-rv5j1201	1554	53	stored	store	VBD
cord-022561-rv5j1201	1554	54	materials	material	NNS
cord-022561-rv5j1201	1554	55	,	,	,
cord-022561-rv5j1201	1554	56	or	or	CC
cord-022561-rv5j1201	1554	57	neoplastic	neoplastic	JJ
cord-022561-rv5j1201	1554	58	cells	cell	NNS
cord-022561-rv5j1201	1554	59	(	(	-LRB-
cord-022561-rv5j1201	1554	60	see	see	VB
cord-022561-rv5j1201	1554	61	Splenomegaly	Splenomegaly	NNP
cord-022561-rv5j1201	1554	62	and	and	CC
cord-022561-rv5j1201	1554	63	Table	Table	NNP
cord-022561-rv5j1201	1554	64	13	13	CD
cord-022561-rv5j1201	1554	65	-5	-5	CD
cord-022561-rv5j1201	1554	66	)	)	-RRB-
cord-022561-rv5j1201	1554	67	.	.	.
cord-022561-rv5j1201	1555	1	The	the	DT
cord-022561-rv5j1201	1555	2	spleen	spleen	NNS
cord-022561-rv5j1201	1555	3	may	may	MD
cord-022561-rv5j1201	1555	4	be	be	VB
cord-022561-rv5j1201	1555	5	measured	measure	VBN
cord-022561-rv5j1201	1555	6	and	and	CC
cord-022561-rv5j1201	1555	7	weighed	weigh	VBD
cord-022561-rv5j1201	1555	8	,	,	,
cord-022561-rv5j1201	1555	9	but	but	CC
cord-022561-rv5j1201	1555	10	because	because	IN
cord-022561-rv5j1201	1555	11	of	of	IN
cord-022561-rv5j1201	1555	12	the	the	DT
cord-022561-rv5j1201	1555	13	wide	wide	JJ
cord-022561-rv5j1201	1555	14	variation	variation	NN
cord-022561-rv5j1201	1555	15	in	in	IN
cord-022561-rv5j1201	1555	16	the	the	DT
cord-022561-rv5j1201	1555	17	dimensions	dimension	NNS
cord-022561-rv5j1201	1555	18	and	and	CC
cord-022561-rv5j1201	1555	19	weight	weight	NN
cord-022561-rv5j1201	1555	20	of	of	IN
cord-022561-rv5j1201	1555	21	normal	normal	JJ
cord-022561-rv5j1201	1555	22	spleens	spleen	NNS
cord-022561-rv5j1201	1555	23	and	and	CC
cord-022561-rv5j1201	1555	24	the	the	DT
cord-022561-rv5j1201	1555	25	amount	amount	NN
cord-022561-rv5j1201	1555	26	of	of	IN
cord-022561-rv5j1201	1555	27	blood	blood	NN
cord-022561-rv5j1201	1555	28	stored	store	VBN
cord-022561-rv5j1201	1555	29	,	,	,
cord-022561-rv5j1201	1555	30	this	this	DT
cord-022561-rv5j1201	1555	31	information	information	NN
cord-022561-rv5j1201	1555	32	is	be	VBZ
cord-022561-rv5j1201	1555	33	difficult	difficult	JJ
cord-022561-rv5j1201	1555	34	to	to	TO
cord-022561-rv5j1201	1555	35	interpret	interpret	VB
cord-022561-rv5j1201	1555	36	.	.	.
cord-022561-rv5j1201	1556	1	It	-PRON-	PRP
cord-022561-rv5j1201	1556	2	is	be	VBZ
cord-022561-rv5j1201	1556	3	essential	essential	JJ
cord-022561-rv5j1201	1556	4	that	that	IN
cord-022561-rv5j1201	1556	5	spleens	spleen	NNS
cord-022561-rv5j1201	1556	6	with	with	IN
cord-022561-rv5j1201	1556	7	one	one	CD
cord-022561-rv5j1201	1556	8	or	or	CC
cord-022561-rv5j1201	1556	9	more	more	JJR
cord-022561-rv5j1201	1556	10	nodules	nodule	NNS
cord-022561-rv5j1201	1556	11	also	also	RB
cord-022561-rv5j1201	1556	12	be	be	VBP
cord-022561-rv5j1201	1556	13	serially	serially	RB
cord-022561-rv5j1201	1556	14	sectioned	section	VBN
cord-022561-rv5j1201	1556	15	and	and	CC
cord-022561-rv5j1201	1556	16	the	the	DT
cord-022561-rv5j1201	1556	17	nodules	nodule	NNS
cord-022561-rv5j1201	1556	18	evaluated	evaluate	VBN
cord-022561-rv5j1201	1556	19	for	for	IN
cord-022561-rv5j1201	1556	20	size	size	NN
cord-022561-rv5j1201	1556	21	,	,	,
cord-022561-rv5j1201	1556	22	shape	shape	NN
cord-022561-rv5j1201	1556	23	,	,	,
cord-022561-rv5j1201	1556	24	and	and	CC
cord-022561-rv5j1201	1556	25	consistency	consistency	NN
cord-022561-rv5j1201	1556	26	.	.	.
cord-022561-rv5j1201	1557	1	Nodules	nodule	NNS
cord-022561-rv5j1201	1557	2	may	may	MD
cord-022561-rv5j1201	1557	3	be	be	VB
cord-022561-rv5j1201	1557	4	dark	dark	JJ
cord-022561-rv5j1201	1557	5	red	red	JJ
cord-022561-rv5j1201	1557	6	and	and	CC
cord-022561-rv5j1201	1557	7	ooze	ooze	NN
cord-022561-rv5j1201	1557	8	blood	blood	NN
cord-022561-rv5j1201	1557	9	on	on	IN
cord-022561-rv5j1201	1557	10	cut	cut	NN
cord-022561-rv5j1201	1557	11	surface	surface	NN
cord-022561-rv5j1201	1557	12	,	,	,
cord-022561-rv5j1201	1557	13	white	white	JJ
cord-022561-rv5j1201	1557	14	-	-	HYPH
cord-022561-rv5j1201	1557	15	tan	tan	NN
cord-022561-rv5j1201	1557	16	with	with	IN
cord-022561-rv5j1201	1557	17	a	a	DT
cord-022561-rv5j1201	1557	18	more	more	RBR
cord-022561-rv5j1201	1557	19	firm	firm	JJ
cord-022561-rv5j1201	1557	20	texture	texture	NN
cord-022561-rv5j1201	1557	21	,	,	,
cord-022561-rv5j1201	1557	22	or	or	CC
cord-022561-rv5j1201	1557	23	a	a	DT
cord-022561-rv5j1201	1557	24	mixture	mixture	NN
cord-022561-rv5j1201	1557	25	of	of	IN
cord-022561-rv5j1201	1557	26	both	both	DT
cord-022561-rv5j1201	1557	27	.	.	.
cord-022561-rv5j1201	1558	1	Multiple	multiple	JJ
cord-022561-rv5j1201	1558	2	wedge	wedge	NN
cord-022561-rv5j1201	1558	3	sections	section	NNS
cord-022561-rv5j1201	1558	4	that	that	WDT
cord-022561-rv5j1201	1558	5	include	include	VBP
cord-022561-rv5j1201	1558	6	the	the	DT
cord-022561-rv5j1201	1558	7	interface	interface	NN
cord-022561-rv5j1201	1558	8	between	between	IN
cord-022561-rv5j1201	1558	9	a	a	DT
cord-022561-rv5j1201	1558	10	nodule	nodule	NN
cord-022561-rv5j1201	1558	11	and	and	CC
cord-022561-rv5j1201	1558	12	the	the	DT
cord-022561-rv5j1201	1558	13	adjacent	adjacent	JJ
cord-022561-rv5j1201	1558	14	nonmass	nonmass	NN
cord-022561-rv5j1201	1558	15	spleen	spleen	NNS
cord-022561-rv5j1201	1558	16	should	should	MD
cord-022561-rv5j1201	1558	17	be	be	VB
cord-022561-rv5j1201	1558	18	collected	collect	VBN
cord-022561-rv5j1201	1558	19	,	,	,
cord-022561-rv5j1201	1558	20	because	because	IN
cord-022561-rv5j1201	1558	21	the	the	DT
cord-022561-rv5j1201	1558	22	center	center	NN
cord-022561-rv5j1201	1558	23	of	of	IN
cord-022561-rv5j1201	1558	24	the	the	DT
cord-022561-rv5j1201	1558	25	nodules	nodule	NNS
cord-022561-rv5j1201	1558	26	often	often	RB
cord-022561-rv5j1201	1558	27	consists	consist	VBZ
cord-022561-rv5j1201	1558	28	only	only	RB
cord-022561-rv5j1201	1558	29	of	of	IN
cord-022561-rv5j1201	1558	30	hemorrhage	hemorrhage	NN
cord-022561-rv5j1201	1558	31	and	and	CC
cord-022561-rv5j1201	1558	32	necrosis	necrosis	NN
cord-022561-rv5j1201	1558	33	,	,	,
cord-022561-rv5j1201	1558	34	and	and	CC
cord-022561-rv5j1201	1558	35	neoplasms	neoplasm	NNS
cord-022561-rv5j1201	1558	36	may	may	MD
cord-022561-rv5j1201	1558	37	be	be	VB
cord-022561-rv5j1201	1558	38	missed	miss	VBN
cord-022561-rv5j1201	1558	39	.	.	.
cord-022561-rv5j1201	1559	1	The	the	DT
cord-022561-rv5j1201	1559	2	color	color	NN
cord-022561-rv5j1201	1559	3	of	of	IN
cord-022561-rv5j1201	1559	4	the	the	DT
cord-022561-rv5j1201	1559	5	capsular	capsular	JJ
cord-022561-rv5j1201	1559	6	surface	surface	NN
cord-022561-rv5j1201	1559	7	of	of	IN
cord-022561-rv5j1201	1559	8	the	the	DT
cord-022561-rv5j1201	1559	9	spleen	spleen	NNS
cord-022561-rv5j1201	1559	10	also	also	RB
cord-022561-rv5j1201	1559	11	varies	vary	VBZ
cord-022561-rv5j1201	1559	12	among	among	IN
cord-022561-rv5j1201	1559	13	species	specie	NNS
cord-022561-rv5j1201	1559	14	of	of	IN
cord-022561-rv5j1201	1559	15	domestic	domestic	JJ
cord-022561-rv5j1201	1559	16	animals	animal	NNS
cord-022561-rv5j1201	1559	17	and	and	CC
cord-022561-rv5j1201	1559	18	depends	depend	VBZ
cord-022561-rv5j1201	1559	19	on	on	IN
cord-022561-rv5j1201	1559	20	the	the	DT
cord-022561-rv5j1201	1559	21	opacity	opacity	NN
cord-022561-rv5j1201	1559	22	or	or	CC
cord-022561-rv5j1201	1559	23	translucence	translucence	NN
cord-022561-rv5j1201	1559	24	of	of	IN
cord-022561-rv5j1201	1559	25	the	the	DT
cord-022561-rv5j1201	1559	26	splenic	splenic	JJ
cord-022561-rv5j1201	1559	27	capsule	capsule	NN
cord-022561-rv5j1201	1559	28	.	.	.
cord-022561-rv5j1201	1560	1	The	the	DT
cord-022561-rv5j1201	1560	2	degree	degree	NN
cord-022561-rv5j1201	1560	3	of	of	IN
cord-022561-rv5j1201	1560	4	opacity	opacity	NN
cord-022561-rv5j1201	1560	5	of	of	IN
cord-022561-rv5j1201	1560	6	the	the	DT
cord-022561-rv5j1201	1560	7	capsule	capsule	NN
cord-022561-rv5j1201	1560	8	is	be	VBZ
cord-022561-rv5j1201	1560	9	a	a	DT
cord-022561-rv5j1201	1560	10	function	function	NN
cord-022561-rv5j1201	1560	11	of	of	IN
cord-022561-rv5j1201	1560	12	its	-PRON-	PRP$
cord-022561-rv5j1201	1560	13	thickness	thickness	NN
cord-022561-rv5j1201	1560	14	and	and	CC
cord-022561-rv5j1201	1560	15	the	the	DT
cord-022561-rv5j1201	1560	16	amount	amount	NN
cord-022561-rv5j1201	1560	17	of	of	IN
cord-022561-rv5j1201	1560	18	collagen	collagen	NN
cord-022561-rv5j1201	1560	19	.	.	.
cord-022561-rv5j1201	1561	1	The	the	DT
cord-022561-rv5j1201	1561	2	splenic	splenic	JJ
cord-022561-rv5j1201	1561	3	capsules	capsule	NNS
cord-022561-rv5j1201	1561	4	of	of	IN
cord-022561-rv5j1201	1561	5	horses	horse	NNS
cord-022561-rv5j1201	1561	6	and	and	CC
cord-022561-rv5j1201	1561	7	ruminants	ruminant	NNS
cord-022561-rv5j1201	1561	8	are	be	VBP
cord-022561-rv5j1201	1561	9	thick	thick	JJ
cord-022561-rv5j1201	1561	10	and	and	CC
cord-022561-rv5j1201	1561	11	usually	usually	RB
cord-022561-rv5j1201	1561	12	appear	appear	VBP
cord-022561-rv5j1201	1561	13	gray	gray	JJ
cord-022561-rv5j1201	1561	14	because	because	IN
cord-022561-rv5j1201	1561	15	the	the	DT
cord-022561-rv5j1201	1561	16	color	color	NN
cord-022561-rv5j1201	1561	17	of	of	IN
cord-022561-rv5j1201	1561	18	the	the	DT
cord-022561-rv5j1201	1561	19	red	red	JJ
cord-022561-rv5j1201	1561	20	pulp	pulp	NN
cord-022561-rv5j1201	1561	21	is	be	VBZ
cord-022561-rv5j1201	1561	22	not	not	RB
cord-022561-rv5j1201	1561	23	visible	visible	JJ
cord-022561-rv5j1201	1561	24	through	through	IN
cord-022561-rv5j1201	1561	25	the	the	DT
cord-022561-rv5j1201	1561	26	capsule	capsule	NN
cord-022561-rv5j1201	1561	27	.	.	.
cord-022561-rv5j1201	1562	1	In	in	IN
cord-022561-rv5j1201	1562	2	the	the	DT
cord-022561-rv5j1201	1562	3	pig	pig	NN
cord-022561-rv5j1201	1562	4	,	,	,
cord-022561-rv5j1201	1562	5	dog	dog	NN
cord-022561-rv5j1201	1562	6	,	,	,
cord-022561-rv5j1201	1562	7	and	and	CC
cord-022561-rv5j1201	1562	8	cat	cat	NN
cord-022561-rv5j1201	1562	9	,	,	,
cord-022561-rv5j1201	1562	10	the	the	DT
cord-022561-rv5j1201	1562	11	splenic	splenic	JJ
cord-022561-rv5j1201	1562	12	capsule	capsule	NN
cord-022561-rv5j1201	1562	13	is	be	VBZ
cord-022561-rv5j1201	1562	14	thin	thin	JJ
cord-022561-rv5j1201	1562	15	,	,	,
cord-022561-rv5j1201	1562	16	and	and	CC
cord-022561-rv5j1201	1562	17	thus	thus	RB
cord-022561-rv5j1201	1562	18	the	the	DT
cord-022561-rv5j1201	1562	19	surface	surface	NN
cord-022561-rv5j1201	1562	20	of	of	IN
cord-022561-rv5j1201	1562	21	the	the	DT
cord-022561-rv5j1201	1562	22	spleen	spleen	NN
cord-022561-rv5j1201	1562	23	is	be	VBZ
cord-022561-rv5j1201	1562	24	red	red	JJ
cord-022561-rv5j1201	1562	25	.	.	.
cord-022561-rv5j1201	1563	1	The	the	DT
cord-022561-rv5j1201	1563	2	tenseness	tenseness	NN
cord-022561-rv5j1201	1563	3	of	of	IN
cord-022561-rv5j1201	1563	4	the	the	DT
cord-022561-rv5j1201	1563	5	capsule	capsule	NN
cord-022561-rv5j1201	1563	6	depends	depend	VBZ
cord-022561-rv5j1201	1563	7	on	on	IN
cord-022561-rv5j1201	1563	8	how	how	WRB
cord-022561-rv5j1201	1563	9	much	much	JJ
cord-022561-rv5j1201	1563	10	the	the	DT
cord-022561-rv5j1201	1563	11	splenic	splenic	JJ
cord-022561-rv5j1201	1563	12	parenchyma	parenchyma	NN
cord-022561-rv5j1201	1563	13	is	be	VBZ
cord-022561-rv5j1201	1563	14	distended	distend	VBN
cord-022561-rv5j1201	1563	15	;	;	:
cord-022561-rv5j1201	1563	16	storage	storage	NN
cord-022561-rv5j1201	1563	17	spleens	spleen	NNS
cord-022561-rv5j1201	1563	18	devoid	devoid	JJ
cord-022561-rv5j1201	1563	19	of	of	IN
cord-022561-rv5j1201	1563	20	blood	blood	NN
cord-022561-rv5j1201	1563	21	usually	usually	RB
cord-022561-rv5j1201	1563	22	have	have	VBP
cord-022561-rv5j1201	1563	23	a	a	DT
cord-022561-rv5j1201	1563	24	wrinkled	wrinkled	JJ
cord-022561-rv5j1201	1563	25	surface	surface	NN
cord-022561-rv5j1201	1563	26	.	.	.
cord-022561-rv5j1201	1564	1	Irregular	irregular	JJ
cord-022561-rv5j1201	1564	2	contraction	contraction	NN
cord-022561-rv5j1201	1564	3	of	of	IN
cord-022561-rv5j1201	1564	4	storage	storage	NN
cord-022561-rv5j1201	1564	5	spleens	spleen	NNS
cord-022561-rv5j1201	1564	6	is	be	VBZ
cord-022561-rv5j1201	1564	7	common	common	JJ
cord-022561-rv5j1201	1564	8	,	,	,
cord-022561-rv5j1201	1564	9	especially	especially	RB
cord-022561-rv5j1201	1564	10	in	in	IN
cord-022561-rv5j1201	1564	11	dogs	dog	NNS
cord-022561-rv5j1201	1564	12	,	,	,
cord-022561-rv5j1201	1564	13	and	and	CC
cord-022561-rv5j1201	1564	14	consists	consist	VBZ
cord-022561-rv5j1201	1564	15	of	of	IN
cord-022561-rv5j1201	1564	16	nonuniform	nonuniform	JJ
cord-022561-rv5j1201	1564	17	areas	area	NNS
cord-022561-rv5j1201	1564	18	of	of	IN
cord-022561-rv5j1201	1564	19	congestion	congestion	NN
cord-022561-rv5j1201	1564	20	with	with	IN
cord-022561-rv5j1201	1564	21	intermingled	intermingle	VBN
cord-022561-rv5j1201	1564	22	contracted	contract	VBN
cord-022561-rv5j1201	1564	23	and	and	CC
cord-022561-rv5j1201	1564	24	wrinkled	wrinkled	JJ
cord-022561-rv5j1201	1564	25	regions	region	NNS
cord-022561-rv5j1201	1564	26	.	.	.
cord-022561-rv5j1201	1565	1	Lymph	lymph	NN
cord-022561-rv5j1201	1565	2	nodes	node	NNS
cord-022561-rv5j1201	1565	3	should	should	MD
cord-022561-rv5j1201	1565	4	be	be	VB
cord-022561-rv5j1201	1565	5	dissected	dissect	VBN
cord-022561-rv5j1201	1565	6	free	free	JJ
cord-022561-rv5j1201	1565	7	of	of	IN
cord-022561-rv5j1201	1565	8	fat	fat	JJ
cord-022561-rv5j1201	1565	9	and	and	CC
cord-022561-rv5j1201	1565	10	connective	connective	JJ
cord-022561-rv5j1201	1565	11	tissue	tissue	NN
cord-022561-rv5j1201	1565	12	,	,	,
cord-022561-rv5j1201	1565	13	and	and	CC
cord-022561-rv5j1201	1565	14	any	any	DT
cord-022561-rv5j1201	1565	15	firm	firm	JJ
cord-022561-rv5j1201	1565	16	attachment	attachment	NN
cord-022561-rv5j1201	1565	17	to	to	IN
cord-022561-rv5j1201	1565	18	adjacent	adjacent	JJ
cord-022561-rv5j1201	1565	19	tissues	tissue	NNS
cord-022561-rv5j1201	1565	20	should	should	MD
cord-022561-rv5j1201	1565	21	be	be	VB
cord-022561-rv5j1201	1565	22	noted	note	VBN
cord-022561-rv5j1201	1565	23	because	because	IN
cord-022561-rv5j1201	1565	24	these	these	DT
cord-022561-rv5j1201	1565	25	attachments	attachment	NNS
cord-022561-rv5j1201	1565	26	may	may	MD
cord-022561-rv5j1201	1565	27	indicate	indicate	VB
cord-022561-rv5j1201	1565	28	neoplastic	neoplastic	JJ
cord-022561-rv5j1201	1565	29	infiltration	infiltration	NN
cord-022561-rv5j1201	1565	30	through	through	IN
cord-022561-rv5j1201	1565	31	the	the	DT
cord-022561-rv5j1201	1565	32	capsule	capsule	NN
cord-022561-rv5j1201	1565	33	.	.	.
cord-022561-rv5j1201	1566	1	Gross	gross	JJ
cord-022561-rv5j1201	1566	2	examination	examination	NN
cord-022561-rv5j1201	1566	3	includes	include	VBZ
cord-022561-rv5j1201	1566	4	evaluating	evaluate	VBG
cord-022561-rv5j1201	1566	5	size	size	NN
cord-022561-rv5j1201	1566	6	(	(	-LRB-
cord-022561-rv5j1201	1566	7	measurement	measurement	NN
cord-022561-rv5j1201	1566	8	or	or	CC
cord-022561-rv5j1201	1566	9	weight	weight	NN
cord-022561-rv5j1201	1566	10	)	)	-RRB-
cord-022561-rv5j1201	1566	11	,	,	,
cord-022561-rv5j1201	1566	12	shape	shape	NN
cord-022561-rv5j1201	1566	13	,	,	,
cord-022561-rv5j1201	1566	14	and	and	CC
cord-022561-rv5j1201	1566	15	whether	whether	IN
cord-022561-rv5j1201	1566	16	the	the	DT
cord-022561-rv5j1201	1566	17	capsule	capsule	NN
cord-022561-rv5j1201	1566	18	is	be	VBZ
cord-022561-rv5j1201	1566	19	intact	intact	JJ
cord-022561-rv5j1201	1566	20	.	.	.
cord-022561-rv5j1201	1567	1	The	the	DT
cord-022561-rv5j1201	1567	2	cut	cut	NN
cord-022561-rv5j1201	1567	3	surface	surface	NN
cord-022561-rv5j1201	1567	4	is	be	VBZ
cord-022561-rv5j1201	1567	5	examined	examine	VBN
cord-022561-rv5j1201	1567	6	for	for	IN
cord-022561-rv5j1201	1567	7	the	the	DT
cord-022561-rv5j1201	1567	8	presence	presence	NN
cord-022561-rv5j1201	1567	9	of	of	IN
cord-022561-rv5j1201	1567	10	bulging	bulge	VBG
cord-022561-rv5j1201	1567	11	tissue	tissue	NN
cord-022561-rv5j1201	1567	12	,	,	,
cord-022561-rv5j1201	1567	13	edema	edema	NN
cord-022561-rv5j1201	1567	14	,	,	,
cord-022561-rv5j1201	1567	15	congestion	congestion	NN
cord-022561-rv5j1201	1567	16	,	,	,
cord-022561-rv5j1201	1567	17	exudate	exudate	NN
cord-022561-rv5j1201	1567	18	,	,	,
cord-022561-rv5j1201	1567	19	discoloration	discoloration	NN
cord-022561-rv5j1201	1567	20	(	(	-LRB-
cord-022561-rv5j1201	1567	21	see	see	VB
cord-022561-rv5j1201	1567	22	Pigmentation	pigmentation	NN
cord-022561-rv5j1201	1567	23	)	)	-RRB-
cord-022561-rv5j1201	1567	24	,	,	,
cord-022561-rv5j1201	1567	25	obscuration	obscuration	NN
cord-022561-rv5j1201	1567	26	of	of	IN
cord-022561-rv5j1201	1567	27	the	the	DT
cord-022561-rv5j1201	1567	28	normal	normal	JJ
cord-022561-rv5j1201	1567	29	architecture	architecture	NN
cord-022561-rv5j1201	1567	30	,	,	,
cord-022561-rv5j1201	1567	31	and	and	CC
cord-022561-rv5j1201	1567	32	masses	masse	NNS
cord-022561-rv5j1201	1567	33	such	such	JJ
cord-022561-rv5j1201	1567	34	as	as	IN
cord-022561-rv5j1201	1567	35	abscesses	abscess	NNS
cord-022561-rv5j1201	1567	36	,	,	,
cord-022561-rv5j1201	1567	37	granulomas	granuloma	NNS
cord-022561-rv5j1201	1567	38	,	,	,
cord-022561-rv5j1201	1567	39	and	and	CC
cord-022561-rv5j1201	1567	40	discrete	discrete	JJ
cord-022561-rv5j1201	1567	41	neoplasms	neoplasm	NNS
cord-022561-rv5j1201	1567	42	.	.	.
cord-022561-rv5j1201	1568	1	Cytologic	cytologic	JJ
cord-022561-rv5j1201	1568	2	evaluation	evaluation	NN
cord-022561-rv5j1201	1568	3	of	of	IN
cord-022561-rv5j1201	1568	4	superficial	superficial	JJ
cord-022561-rv5j1201	1568	5	lymph	lymph	NN
cord-022561-rv5j1201	1568	6	nodes	node	NNS
cord-022561-rv5j1201	1568	7	through	through	IN
cord-022561-rv5j1201	1568	8	fine	fine	JJ
cord-022561-rv5j1201	1568	9	-	-	HYPH
cord-022561-rv5j1201	1568	10	needle	needle	NN
cord-022561-rv5j1201	1568	11	aspirates	aspirate	NNS
cord-022561-rv5j1201	1568	12	provides	provide	VBZ
cord-022561-rv5j1201	1568	13	excellent	excellent	JJ
cord-022561-rv5j1201	1568	14	cellular	cellular	JJ
cord-022561-rv5j1201	1568	15	detail	detail	NN
cord-022561-rv5j1201	1568	16	and	and	CC
cord-022561-rv5j1201	1568	17	often	often	RB
cord-022561-rv5j1201	1568	18	yields	yield	VBZ
cord-022561-rv5j1201	1568	19	a	a	DT
cord-022561-rv5j1201	1568	20	diagnosis	diagnosis	NN
cord-022561-rv5j1201	1568	21	.	.	.
cord-022561-rv5j1201	1569	1	However	however	RB
cord-022561-rv5j1201	1569	2	,	,	,
cord-022561-rv5j1201	1569	3	diagnosis	diagnosis	NN
cord-022561-rv5j1201	1569	4	of	of	IN
cord-022561-rv5j1201	1569	5	certain	certain	JJ
cord-022561-rv5j1201	1569	6	diseases	disease	NNS
cord-022561-rv5j1201	1569	7	(	(	-LRB-
cord-022561-rv5j1201	1569	8	including	include	VBG
cord-022561-rv5j1201	1569	9	lymphomas	lymphoma	NNS
cord-022561-rv5j1201	1569	10	for	for	IN
cord-022561-rv5j1201	1569	11	complete	complete	JJ
cord-022561-rv5j1201	1569	12	World	World	NNP
cord-022561-rv5j1201	1569	13	Health	Health	NNP
cord-022561-rv5j1201	1569	14	Organization	Organization	NNP
cord-022561-rv5j1201	1569	15	[	[	-LRB-
cord-022561-rv5j1201	1569	16	WHO	who	WP
cord-022561-rv5j1201	1569	17	]	]	-RRB-
cord-022561-rv5j1201	1569	18	classification	classification	NN
cord-022561-rv5j1201	1569	19	)	)	-RRB-
cord-022561-rv5j1201	1569	20	requires	require	VBZ
cord-022561-rv5j1201	1569	21	architectural	architectural	JJ
cord-022561-rv5j1201	1569	22	assessments	assessment	NNS
cord-022561-rv5j1201	1569	23	,	,	,
cord-022561-rv5j1201	1569	24	and	and	CC
cord-022561-rv5j1201	1569	25	therefore	therefore	RB
cord-022561-rv5j1201	1569	26	cytologic	cytologic	JJ
cord-022561-rv5j1201	1569	27	or	or	CC
cord-022561-rv5j1201	1569	28	small	small	JJ
cord-022561-rv5j1201	1569	29	histologic	histologic	JJ
cord-022561-rv5j1201	1569	30	samples	sample	NNS
cord-022561-rv5j1201	1569	31	are	be	VBP
cord-022561-rv5j1201	1569	32	not	not	RB
cord-022561-rv5j1201	1569	33	sufficient	sufficient	JJ
cord-022561-rv5j1201	1569	34	.	.	.
cord-022561-rv5j1201	1570	1	Tru	Tru	NNP
cord-022561-rv5j1201	1570	2	-	-	HYPH
cord-022561-rv5j1201	1570	3	Cut	Cut	VBN
cord-022561-rv5j1201	1570	4	biopsies	biopsy	NNS
cord-022561-rv5j1201	1570	5	are	be	VBP
cord-022561-rv5j1201	1570	6	not	not	RB
cord-022561-rv5j1201	1570	7	ideal	ideal	JJ
cord-022561-rv5j1201	1570	8	,	,	,
cord-022561-rv5j1201	1570	9	but	but	CC
cord-022561-rv5j1201	1570	10	a	a	DT
cord-022561-rv5j1201	1570	11	2-mm	2-mm	CD
cord-022561-rv5j1201	1570	12	Tru	Tru	NNP
cord-022561-rv5j1201	1570	13	-	-	HYPH
cord-022561-rv5j1201	1570	14	Cut	cut	JJ
cord-022561-rv5j1201	1570	15	needle	needle	NN
cord-022561-rv5j1201	1570	16	may	may	MD
cord-022561-rv5j1201	1570	17	provide	provide	VB
cord-022561-rv5j1201	1570	18	adequate	adequate	JJ
cord-022561-rv5j1201	1570	19	tissue	tissue	NN
cord-022561-rv5j1201	1570	20	.	.	.
cord-022561-rv5j1201	1571	1	The	the	DT
cord-022561-rv5j1201	1571	2	surgeon	surgeon	NN
cord-022561-rv5j1201	1571	3	or	or	CC
cord-022561-rv5j1201	1571	4	pathologist	pathologist	NN
cord-022561-rv5j1201	1571	5	must	must	MD
cord-022561-rv5j1201	1571	6	handle	handle	VB
cord-022561-rv5j1201	1571	7	lymph	lymph	NN
cord-022561-rv5j1201	1571	8	nodes	node	NNS
cord-022561-rv5j1201	1571	9	carefully	carefully	RB
cord-022561-rv5j1201	1571	10	to	to	TO
cord-022561-rv5j1201	1571	11	minimize	minimize	VB
cord-022561-rv5j1201	1571	12	artifacts	artifact	NNS
cord-022561-rv5j1201	1571	13	.	.	.
cord-022561-rv5j1201	1572	1	Compression	compression	NN
cord-022561-rv5j1201	1572	2	(	(	-LRB-
cord-022561-rv5j1201	1572	3	e.g.	e.g.	RB
cord-022561-rv5j1201	1572	4	,	,	,
cord-022561-rv5j1201	1572	5	squeezing	squeeze	VBG
cord-022561-rv5j1201	1572	6	with	with	IN
cord-022561-rv5j1201	1572	7	forceps	forceps	NNS
cord-022561-rv5j1201	1572	8	)	)	-RRB-
cord-022561-rv5j1201	1572	9	may	may	MD
cord-022561-rv5j1201	1572	10	cause	cause	VB
cord-022561-rv5j1201	1572	11	crush	crush	NN
cord-022561-rv5j1201	1572	12	artifacts	artifact	NNS
cord-022561-rv5j1201	1572	13	,	,	,
cord-022561-rv5j1201	1572	14	usually	usually	RB
cord-022561-rv5j1201	1572	15	resulting	result	VBG
cord-022561-rv5j1201	1572	16	in	in	IN
cord-022561-rv5j1201	1572	17	nuclear	nuclear	JJ
cord-022561-rv5j1201	1572	18	"	"	``
cord-022561-rv5j1201	1572	19	streaming	streaming	NN
cord-022561-rv5j1201	1572	20	.	.	.
cord-022561-rv5j1201	1573	1	"	"	``
cord-022561-rv5j1201	1573	2	Immediately	immediately	RB
cord-022561-rv5j1201	1573	3	after	after	IN
cord-022561-rv5j1201	1573	4	removal	removal	NN
cord-022561-rv5j1201	1573	5	,	,	,
cord-022561-rv5j1201	1573	6	imprints	imprint	NNS
cord-022561-rv5j1201	1573	7	/	/	SYM
cord-022561-rv5j1201	1573	8	impression	impression	NN
cord-022561-rv5j1201	1573	9	smears	smear	NNS
cord-022561-rv5j1201	1573	10	should	should	MD
cord-022561-rv5j1201	1573	11	be	be	VB
cord-022561-rv5j1201	1573	12	prepared	prepared	JJ
cord-022561-rv5j1201	1573	13	and	and	CC
cord-022561-rv5j1201	1573	14	then	then	RB
cord-022561-rv5j1201	1573	15	kept	keep	VBD
cord-022561-rv5j1201	1573	16	away	away	RB
cord-022561-rv5j1201	1573	17	from	from	IN
cord-022561-rv5j1201	1573	18	formalin	formalin	NN
cord-022561-rv5j1201	1573	19	fumes	fume	NNS
cord-022561-rv5j1201	1573	20	.	.	.
cord-022561-rv5j1201	1574	1	Formalin	formalin	JJ
cord-022561-rv5j1201	1574	2	fixation	fixation	NN
cord-022561-rv5j1201	1574	3	(	(	-LRB-
cord-022561-rv5j1201	1574	4	in	in	IN
cord-022561-rv5j1201	1574	5	this	this	DT
cord-022561-rv5j1201	1574	6	case	case	NN
cord-022561-rv5j1201	1574	7	by	by	IN
cord-022561-rv5j1201	1574	8	formaldehyde	formaldehyde	NN
cord-022561-rv5j1201	1574	9	fumes	fume	NNS
cord-022561-rv5j1201	1574	10	)	)	-RRB-
cord-022561-rv5j1201	1574	11	destroys	destroy	VBZ
cord-022561-rv5j1201	1574	12	the	the	DT
cord-022561-rv5j1201	1574	13	differential	differential	JJ
cord-022561-rv5j1201	1574	14	staining	staining	NN
cord-022561-rv5j1201	1574	15	seen	see	VBN
cord-022561-rv5j1201	1574	16	with	with	IN
cord-022561-rv5j1201	1574	17	Romanowsky	Romanowsky	NNP
cord-022561-rv5j1201	1574	18	stains	stain	NNS
cord-022561-rv5j1201	1574	19	such	such	JJ
cord-022561-rv5j1201	1574	20	as	as	IN
cord-022561-rv5j1201	1574	21	Wright	Wright	NNP
cord-022561-rv5j1201	1574	22	's	's	POS
cord-022561-rv5j1201	1574	23	and	and	CC
cord-022561-rv5j1201	1574	24	Giemsa	Giemsa	NNP
cord-022561-rv5j1201	1574	25	and	and	CC
cord-022561-rv5j1201	1574	26	results	result	NNS
cord-022561-rv5j1201	1574	27	in	in	IN
cord-022561-rv5j1201	1574	28	diffuse	diffuse	JJ
cord-022561-rv5j1201	1574	29	blue	blue	JJ
cord-022561-rv5j1201	1574	30	staining	staining	NN
cord-022561-rv5j1201	1574	31	.	.	.
cord-022561-rv5j1201	1575	1	Prompt	prompt	JJ
cord-022561-rv5j1201	1575	2	transfer	transfer	NN
cord-022561-rv5j1201	1575	3	of	of	IN
cord-022561-rv5j1201	1575	4	biopsy	biopsy	NN
cord-022561-rv5j1201	1575	5	or	or	CC
cord-022561-rv5j1201	1575	6	postmortem	postmortem	JJ
cord-022561-rv5j1201	1575	7	specimens	specimen	NNS
cord-022561-rv5j1201	1575	8	into	into	IN
cord-022561-rv5j1201	1575	9	fixative	fixative	NN
cord-022561-rv5j1201	1575	10	is	be	VBZ
cord-022561-rv5j1201	1575	11	crucial	crucial	JJ
cord-022561-rv5j1201	1575	12	because	because	IN
cord-022561-rv5j1201	1575	13	delayed	delay	VBN
cord-022561-rv5j1201	1575	14	fixation	fixation	NN
cord-022561-rv5j1201	1575	15	can	can	MD
cord-022561-rv5j1201	1575	16	lead	lead	VB
cord-022561-rv5j1201	1575	17	to	to	IN
cord-022561-rv5j1201	1575	18	numerous	numerous	JJ
cord-022561-rv5j1201	1575	19	artifacts	artifact	NNS
cord-022561-rv5j1201	1575	20	,	,	,
cord-022561-rv5j1201	1575	21	including	include	VBG
cord-022561-rv5j1201	1575	22	an	an	DT
cord-022561-rv5j1201	1575	23	artificial	artificial	JJ
cord-022561-rv5j1201	1575	24	decrease	decrease	NN
cord-022561-rv5j1201	1575	25	in	in	IN
cord-022561-rv5j1201	1575	26	mitotic	mitotic	JJ
cord-022561-rv5j1201	1575	27	index	index	NN
cord-022561-rv5j1201	1575	28	(	(	-LRB-
cord-022561-rv5j1201	1575	29	up	up	IN
cord-022561-rv5j1201	1575	30	to	to	TO
cord-022561-rv5j1201	1575	31	40	40	CD
cord-022561-rv5j1201	1575	32	%	%	NN
cord-022561-rv5j1201	1575	33	reduction	reduction	NN
cord-022561-rv5j1201	1575	34	with	with	IN
cord-022561-rv5j1201	1575	35	a	a	DT
cord-022561-rv5j1201	1575	36	more	more	JJR
cord-022561-rv5j1201	1575	37	than	than	IN
cord-022561-rv5j1201	1575	38	12-hour	12-hour	CD
cord-022561-rv5j1201	1575	39	delay	delay	NN
cord-022561-rv5j1201	1575	40	in	in	IN
cord-022561-rv5j1201	1575	41	fixation	fixation	NN
cord-022561-rv5j1201	1575	42	)	)	-RRB-
cord-022561-rv5j1201	1575	43	;	;	:
cord-022561-rv5j1201	1575	44	this	this	DT
cord-022561-rv5j1201	1575	45	reduction	reduction	NN
cord-022561-rv5j1201	1575	46	can	can	MD
cord-022561-rv5j1201	1575	47	alter	alter	VB
cord-022561-rv5j1201	1575	48	tumor	tumor	NN
cord-022561-rv5j1201	1575	49	classification	classification	NN
cord-022561-rv5j1201	1575	50	and	and	CC
cord-022561-rv5j1201	1575	51	grade	grade	NN
cord-022561-rv5j1201	1575	52	.	.	.
cord-022561-rv5j1201	1576	1	The	the	DT
cord-022561-rv5j1201	1576	2	current	current	JJ
cord-022561-rv5j1201	1576	3	recommendation	recommendation	NN
cord-022561-rv5j1201	1576	4	for	for	IN
cord-022561-rv5j1201	1576	5	the	the	DT
cord-022561-rv5j1201	1576	6	duration	duration	NN
cord-022561-rv5j1201	1576	7	of	of	IN
cord-022561-rv5j1201	1576	8	formalin	formalin	NN
cord-022561-rv5j1201	1576	9	fixation	fixation	NN
cord-022561-rv5j1201	1576	10	is	be	VBZ
cord-022561-rv5j1201	1576	11	16	16	CD
cord-022561-rv5j1201	1576	12	to	to	TO
cord-022561-rv5j1201	1576	13	32	32	CD
cord-022561-rv5j1201	1576	14	hours	hour	NNS
cord-022561-rv5j1201	1576	15	;	;	:
cord-022561-rv5j1201	1576	16	complete	complete	JJ
cord-022561-rv5j1201	1576	17	fixation	fixation	NN
cord-022561-rv5j1201	1576	18	of	of	IN
cord-022561-rv5j1201	1576	19	2-to	2-to	CD
cord-022561-rv5j1201	1576	20	4-mm	4-mm	CD
cord-022561-rv5j1201	1576	21	thick	thick	JJ
cord-022561-rv5j1201	1576	22	tissues	tissue	NNS
cord-022561-rv5j1201	1576	23	is	be	VBZ
cord-022561-rv5j1201	1576	24	likely	likely	JJ
cord-022561-rv5j1201	1576	25	to	to	TO
cord-022561-rv5j1201	1576	26	be	be	VB
cord-022561-rv5j1201	1576	27	achieved	achieve	VBN
cord-022561-rv5j1201	1576	28	after	after	IN
cord-022561-rv5j1201	1576	29	24	24	CD
cord-022561-rv5j1201	1576	30	to	to	TO
cord-022561-rv5j1201	1576	31	48	48	CD
cord-022561-rv5j1201	1576	32	hours	hour	NNS
cord-022561-rv5j1201	1576	33	.	.	.
cord-022561-rv5j1201	1577	1	Both	both	DT
cord-022561-rv5j1201	1577	2	underfixation	underfixation	NN
cord-022561-rv5j1201	1577	3	and	and	CC
cord-022561-rv5j1201	1577	4	overfixation	overfixation	NN
cord-022561-rv5j1201	1577	5	may	may	MD
cord-022561-rv5j1201	1577	6	lead	lead	VB
cord-022561-rv5j1201	1577	7	to	to	IN
cord-022561-rv5j1201	1577	8	difficulties	difficulty	NNS
cord-022561-rv5j1201	1577	9	with	with	IN
cord-022561-rv5j1201	1577	10	antigen	antigen	NN
cord-022561-rv5j1201	1577	11	retrieval	retrieval	NN
cord-022561-rv5j1201	1577	12	for	for	IN
cord-022561-rv5j1201	1577	13	immunohistochemistry	immunohistochemistry	NN
cord-022561-rv5j1201	1577	14	,	,	,
cord-022561-rv5j1201	1577	15	though	though	IN
cord-022561-rv5j1201	1577	16	underfixation	underfixation	NN
cord-022561-rv5j1201	1577	17	is	be	VBZ
cord-022561-rv5j1201	1577	18	considered	consider	VBN
cord-022561-rv5j1201	1577	19	the	the	DT
cord-022561-rv5j1201	1577	20	more	more	RBR
cord-022561-rv5j1201	1577	21	common	common	JJ
cord-022561-rv5j1201	1577	22	and	and	CC
cord-022561-rv5j1201	1577	23	serious	serious	JJ
cord-022561-rv5j1201	1577	24	problem	problem	NN
cord-022561-rv5j1201	1577	25	.	.	.
cord-022561-rv5j1201	1578	1	Thinly	thinly	RB
cord-022561-rv5j1201	1578	2	slicing	slice	VBG
cord-022561-rv5j1201	1578	3	some	some	DT
cord-022561-rv5j1201	1578	4	nodes	node	NNS
cord-022561-rv5j1201	1578	5	may	may	MD
cord-022561-rv5j1201	1578	6	be	be	VB
cord-022561-rv5j1201	1578	7	difficult	difficult	JJ
cord-022561-rv5j1201	1578	8	,	,	,
cord-022561-rv5j1201	1578	9	and	and	CC
cord-022561-rv5j1201	1578	10	allowing	allow	VBG
cord-022561-rv5j1201	1578	11	the	the	DT
cord-022561-rv5j1201	1578	12	node	node	NN
cord-022561-rv5j1201	1578	13	to	to	TO
cord-022561-rv5j1201	1578	14	fix	fix	VB
cord-022561-rv5j1201	1578	15	for	for	IN
cord-022561-rv5j1201	1578	16	1	1	CD
cord-022561-rv5j1201	1578	17	hour	hour	NN
cord-022561-rv5j1201	1578	18	before	before	IN
cord-022561-rv5j1201	1578	19	slicing	slice	VBG
cord-022561-rv5j1201	1578	20	may	may	MD
cord-022561-rv5j1201	1578	21	help	help	VB
cord-022561-rv5j1201	1578	22	.	.	.
cord-022561-rv5j1201	1579	1	Some	some	DT
cord-022561-rv5j1201	1579	2	pathologists	pathologist	NNS
cord-022561-rv5j1201	1579	3	prefer	prefer	VBP
cord-022561-rv5j1201	1579	4	not	not	RB
cord-022561-rv5j1201	1579	5	to	to	TO
cord-022561-rv5j1201	1579	6	incise	incise	VB
cord-022561-rv5j1201	1579	7	very	very	RB
cord-022561-rv5j1201	1579	8	small	small	JJ
cord-022561-rv5j1201	1579	9	lymph	lymph	NN
cord-022561-rv5j1201	1579	10	nodes	node	NNS
cord-022561-rv5j1201	1579	11	to	to	TO
cord-022561-rv5j1201	1579	12	avoid	avoid	VB
cord-022561-rv5j1201	1579	13	compression	compression	NN
cord-022561-rv5j1201	1579	14	artifacts	artifact	NNS
cord-022561-rv5j1201	1579	15	,	,	,
cord-022561-rv5j1201	1579	16	but	but	CC
cord-022561-rv5j1201	1579	17	instead	instead	RB
cord-022561-rv5j1201	1579	18	nick	nick	NNP
cord-022561-rv5j1201	1579	19	the	the	DT
cord-022561-rv5j1201	1579	20	capsule	capsule	NN
cord-022561-rv5j1201	1579	21	to	to	TO
cord-022561-rv5j1201	1579	22	allow	allow	VB
cord-022561-rv5j1201	1579	23	formalin	formalin	NN
cord-022561-rv5j1201	1579	24	penetration	penetration	NN
cord-022561-rv5j1201	1579	25	.	.	.
cord-022561-rv5j1201	1580	1	However	however	RB
cord-022561-rv5j1201	1580	2	,	,	,
cord-022561-rv5j1201	1580	3	fixation	fixation	NN
cord-022561-rv5j1201	1580	4	of	of	IN
cord-022561-rv5j1201	1580	5	unincised	unincised	JJ
cord-022561-rv5j1201	1580	6	lymph	lymph	NN
cord-022561-rv5j1201	1580	7	nodes	node	NNS
cord-022561-rv5j1201	1580	8	can	can	MD
cord-022561-rv5j1201	1580	9	also	also	RB
cord-022561-rv5j1201	1580	10	cause	cause	VB
cord-022561-rv5j1201	1580	11	compression	compression	NN
cord-022561-rv5j1201	1580	12	artifacts	artifact	NNS
cord-022561-rv5j1201	1580	13	because	because	IN
cord-022561-rv5j1201	1580	14	the	the	DT
cord-022561-rv5j1201	1580	15	fibrous	fibrous	JJ
cord-022561-rv5j1201	1580	16	capsule	capsule	NN
cord-022561-rv5j1201	1580	17	contracts	contract	NNS
cord-022561-rv5j1201	1580	18	in	in	IN
cord-022561-rv5j1201	1580	19	the	the	DT
cord-022561-rv5j1201	1580	20	fixative	fixative	NN
cord-022561-rv5j1201	1580	21	.	.	.
cord-022561-rv5j1201	1581	1	Once	once	RB
cord-022561-rv5j1201	1581	2	fixed	fix	VBN
cord-022561-rv5j1201	1581	3	,	,	,
cord-022561-rv5j1201	1581	4	nodes	node	NNS
cord-022561-rv5j1201	1581	5	should	should	MD
cord-022561-rv5j1201	1581	6	be	be	VB
cord-022561-rv5j1201	1581	7	cut	cut	VBN
cord-022561-rv5j1201	1581	8	in	in	IN
cord-022561-rv5j1201	1581	9	uniformly	uniformly	RB
cord-022561-rv5j1201	1581	10	thick	thick	JJ
cord-022561-rv5j1201	1581	11	cross	cross	JJ
cord-022561-rv5j1201	1581	12	section	section	NN
cord-022561-rv5j1201	1581	13	to	to	TO
cord-022561-rv5j1201	1581	14	include	include	VB
cord-022561-rv5j1201	1581	15	both	both	CC
cord-022561-rv5j1201	1581	16	the	the	DT
cord-022561-rv5j1201	1581	17	cortex	cortex	NN
cord-022561-rv5j1201	1581	18	and	and	CC
cord-022561-rv5j1201	1581	19	medulla	medulla	NN
cord-022561-rv5j1201	1581	20	.	.	.
cord-022561-rv5j1201	1582	1	Transverse	transverse	JJ
cord-022561-rv5j1201	1582	2	sections	section	NNS
cord-022561-rv5j1201	1582	3	are	be	VBP
cord-022561-rv5j1201	1582	4	usually	usually	RB
cord-022561-rv5j1201	1582	5	sufficiently	sufficiently	RB
cord-022561-rv5j1201	1582	6	small	small	JJ
cord-022561-rv5j1201	1582	7	to	to	TO
cord-022561-rv5j1201	1582	8	allow	allow	VB
cord-022561-rv5j1201	1582	9	the	the	DT
cord-022561-rv5j1201	1582	10	entire	entire	JJ
cord-022561-rv5j1201	1582	11	cross	cross	NN
cord-022561-rv5j1201	1582	12	section	section	NN
cord-022561-rv5j1201	1582	13	of	of	IN
cord-022561-rv5j1201	1582	14	most	most	JJS
cord-022561-rv5j1201	1582	15	lymph	lymph	NN
cord-022561-rv5j1201	1582	16	nodes	node	NNS
cord-022561-rv5j1201	1582	17	to	to	TO
cord-022561-rv5j1201	1582	18	fit	fit	VB
cord-022561-rv5j1201	1582	19	on	on	IN
cord-022561-rv5j1201	1582	20	one	one	CD
cord-022561-rv5j1201	1582	21	microscopic	microscopic	JJ
cord-022561-rv5j1201	1582	22	slide	slide	NN
cord-022561-rv5j1201	1582	23	,	,	,
cord-022561-rv5j1201	1582	24	which	which	WDT
cord-022561-rv5j1201	1582	25	facilitates	facilitate	VBZ
cord-022561-rv5j1201	1582	26	histologic	histologic	JJ
cord-022561-rv5j1201	1582	27	interpretation	interpretation	NN
cord-022561-rv5j1201	1582	28	.	.	.
cord-022561-rv5j1201	1583	1	The	the	DT
cord-022561-rv5j1201	1583	2	longitudinal	longitudinal	JJ
cord-022561-rv5j1201	1583	3	plane	plane	NN
cord-022561-rv5j1201	1583	4	is	be	VBZ
cord-022561-rv5j1201	1583	5	preferred	prefer	VBN
cord-022561-rv5j1201	1583	6	for	for	IN
cord-022561-rv5j1201	1583	7	porcine	porcine	JJ
cord-022561-rv5j1201	1583	8	lymph	lymph	NN
cord-022561-rv5j1201	1583	9	nodes	node	NNS
cord-022561-rv5j1201	1583	10	because	because	IN
cord-022561-rv5j1201	1583	11	the	the	DT
cord-022561-rv5j1201	1583	12	location	location	NN
cord-022561-rv5j1201	1583	13	and	and	CC
cord-022561-rv5j1201	1583	14	amount	amount	NN
cord-022561-rv5j1201	1583	15	of	of	IN
cord-022561-rv5j1201	1583	16	cortex	cortex	NN
cord-022561-rv5j1201	1583	17	and	and	CC
cord-022561-rv5j1201	1583	18	medulla	medulla	NN
cord-022561-rv5j1201	1583	19	vary	vary	VBP
cord-022561-rv5j1201	1583	20	at	at	IN
cord-022561-rv5j1201	1583	21	different	different	JJ
cord-022561-rv5j1201	1583	22	sites	site	NNS
cord-022561-rv5j1201	1583	23	in	in	IN
cord-022561-rv5j1201	1583	24	transverse	transverse	JJ
cord-022561-rv5j1201	1583	25	sections	section	NNS
cord-022561-rv5j1201	1583	26	.	.	.
cord-022561-rv5j1201	1584	1	molecules	molecule	NNS
cord-022561-rv5j1201	1584	2	)	)	-RRB-
cord-022561-rv5j1201	1584	3	but	but	CC
cord-022561-rv5j1201	1584	4	not	not	RB
cord-022561-rv5j1201	1584	5	self	self	NN
cord-022561-rv5j1201	1584	6	-	-	HYPH
cord-022561-rv5j1201	1584	7	antigens	antigen	NNS
cord-022561-rv5j1201	1584	8	are	be	VBP
cord-022561-rv5j1201	1584	9	permitted	permit	VBN
cord-022561-rv5j1201	1584	10	to	to	TO
cord-022561-rv5j1201	1584	11	mature	mature	VB
cord-022561-rv5j1201	1584	12	by	by	IN
cord-022561-rv5j1201	1584	13	a	a	DT
cord-022561-rv5j1201	1584	14	process	process	NN
cord-022561-rv5j1201	1584	15	called	call	VBN
cord-022561-rv5j1201	1584	16	positive	positive	JJ
cord-022561-rv5j1201	1584	17	selection	selection	NN
cord-022561-rv5j1201	1584	18	.	.	.
cord-022561-rv5j1201	1585	1	Cells	cell	NNS
cord-022561-rv5j1201	1585	2	that	that	WDT
cord-022561-rv5j1201	1585	3	do	do	VBP
cord-022561-rv5j1201	1585	4	not	not	RB
cord-022561-rv5j1201	1585	5	recognize	recognize	VB
cord-022561-rv5j1201	1585	6	MHC	MHC	NNP
cord-022561-rv5j1201	1585	7	molecules	molecule	NNS
cord-022561-rv5j1201	1585	8	are	be	VBP
cord-022561-rv5j1201	1585	9	removed	remove	VBN
cord-022561-rv5j1201	1585	10	by	by	IN
cord-022561-rv5j1201	1585	11	apoptosis	apoptosis	NN
cord-022561-rv5j1201	1585	12	.	.	.
cord-022561-rv5j1201	1586	1	Those	those	DT
cord-022561-rv5j1201	1586	2	T	t	NN
cord-022561-rv5j1201	1586	3	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	1586	4	that	that	WDT
cord-022561-rv5j1201	1586	5	recognize	recognize	VBP
cord-022561-rv5j1201	1586	6	both	both	DT
cord-022561-rv5j1201	1586	7	MHC	MHC	NNP
cord-022561-rv5j1201	1586	8	molecules	molecule	NNS
cord-022561-rv5j1201	1586	9	and	and	CC
cord-022561-rv5j1201	1586	10	self	self	NN
cord-022561-rv5j1201	1586	11	-	-	HYPH
cord-022561-rv5j1201	1586	12	antigens	antigen	NNS
cord-022561-rv5j1201	1586	13	are	be	VBP
cord-022561-rv5j1201	1586	14	removed	remove	VBN
cord-022561-rv5j1201	1586	15	by	by	IN
cord-022561-rv5j1201	1586	16	macrophages	macrophage	NNS
cord-022561-rv5j1201	1586	17	at	at	IN
cord-022561-rv5j1201	1586	18	the	the	DT
cord-022561-rv5j1201	1586	19	corticomedullary	corticomedullary	JJ
cord-022561-rv5j1201	1586	20	junction	junction	NN
cord-022561-rv5j1201	1586	21	,	,	,
cord-022561-rv5j1201	1586	22	a	a	DT
cord-022561-rv5j1201	1586	23	process	process	NN
cord-022561-rv5j1201	1586	24	called	call	VBN
cord-022561-rv5j1201	1586	25	negative	negative	JJ
cord-022561-rv5j1201	1586	26	selection	selection	NN
cord-022561-rv5j1201	1586	27	.	.	.
cord-022561-rv5j1201	1587	1	Because	because	IN
cord-022561-rv5j1201	1587	2	of	of	IN
cord-022561-rv5j1201	1587	3	the	the	DT
cord-022561-rv5j1201	1587	4	rigid	rigid	JJ
cord-022561-rv5j1201	1587	5	differentiation	differentiation	NN
cord-022561-rv5j1201	1587	6	requirements	requirement	NNS
cord-022561-rv5j1201	1587	7	attributable	attributable	JJ
cord-022561-rv5j1201	1587	8	to	to	IN
cord-022561-rv5j1201	1587	9	MHC	MHC	NNP
cord-022561-rv5j1201	1587	10	restriction	restriction	NN
cord-022561-rv5j1201	1587	11	and	and	CC
cord-022561-rv5j1201	1587	12	tolerance	tolerance	NN
cord-022561-rv5j1201	1587	13	(	(	-LRB-
cord-022561-rv5j1201	1587	14	positive	positive	JJ
cord-022561-rv5j1201	1587	15	and	and	CC
cord-022561-rv5j1201	1587	16	negative	negative	JJ
cord-022561-rv5j1201	1587	17	selection	selection	NN
cord-022561-rv5j1201	1587	18	,	,	,
cord-022561-rv5j1201	1587	19	respectively	respectively	RB
cord-022561-rv5j1201	1587	20	)	)	-RRB-
cord-022561-rv5j1201	1587	21	,	,	,
cord-022561-rv5j1201	1587	22	only	only	RB
cord-022561-rv5j1201	1587	23	a	a	DT
cord-022561-rv5j1201	1587	24	small	small	JJ
cord-022561-rv5j1201	1587	25	fraction	fraction	NN
cord-022561-rv5j1201	1587	26	(	(	-LRB-
cord-022561-rv5j1201	1587	27	<	<	NNP
cord-022561-rv5j1201	1587	28	5	5	CD
cord-022561-rv5j1201	1587	29	%	%	NN
cord-022561-rv5j1201	1587	30	)	)	-RRB-
cord-022561-rv5j1201	1587	31	of	of	IN
cord-022561-rv5j1201	1587	32	the	the	DT
cord-022561-rv5j1201	1587	33	developing	develop	VBG
cord-022561-rv5j1201	1587	34	T	t	NN
cord-022561-rv5j1201	1587	35	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	1587	36	that	that	WDT
cord-022561-rv5j1201	1587	37	arrive	arrive	VBP
cord-022561-rv5j1201	1587	38	at	at	IN
cord-022561-rv5j1201	1587	39	the	the	DT
cord-022561-rv5j1201	1587	40	thymus	thymus	NN
cord-022561-rv5j1201	1587	41	from	from	IN
cord-022561-rv5j1201	1587	42	the	the	DT
cord-022561-rv5j1201	1587	43	bone	bone	NN
cord-022561-rv5j1201	1587	44	marrow	marrow	NN
cord-022561-rv5j1201	1587	45	survive	survive	VBP
cord-022561-rv5j1201	1587	46	.	.	.
cord-022561-rv5j1201	1588	1	Mature	mature	JJ
cord-022561-rv5j1201	1588	2	naïve	naïve	JJ
cord-022561-rv5j1201	1588	3	T	t	NN
cord-022561-rv5j1201	1588	4	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	1588	5	exit	exit	VBP
cord-022561-rv5j1201	1588	6	the	the	DT
cord-022561-rv5j1201	1588	7	thymus	thymus	NN
cord-022561-rv5j1201	1588	8	through	through	IN
cord-022561-rv5j1201	1588	9	postcapillary	postcapillary	NNP
cord-022561-rv5j1201	1588	10	venules	venule	NNS
cord-022561-rv5j1201	1588	11	in	in	IN
cord-022561-rv5j1201	1588	12	the	the	DT
cord-022561-rv5j1201	1588	13	corticomedullary	corticomedullary	JJ
cord-022561-rv5j1201	1588	14	region	region	NN
cord-022561-rv5j1201	1588	15	,	,	,
cord-022561-rv5j1201	1588	16	enter	enter	VB
cord-022561-rv5j1201	1588	17	the	the	DT
cord-022561-rv5j1201	1588	18	circulation	circulation	NN
cord-022561-rv5j1201	1588	19	,	,	,
cord-022561-rv5j1201	1588	20	and	and	CC
cord-022561-rv5j1201	1588	21	recirculate	recirculate	VBP
cord-022561-rv5j1201	1588	22	through	through	IN
cord-022561-rv5j1201	1588	23	secondary	secondary	JJ
cord-022561-rv5j1201	1588	24	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	1588	25	tissues	tissue	NNS
cord-022561-rv5j1201	1588	26	,	,	,
cord-022561-rv5j1201	1588	27	primarily	primarily	RB
cord-022561-rv5j1201	1588	28	located	locate	VBN
cord-022561-rv5j1201	1588	29	in	in	IN
cord-022561-rv5j1201	1588	30	the	the	DT
cord-022561-rv5j1201	1588	31	paracortex	paracortex	NN
cord-022561-rv5j1201	1588	32	of	of	IN
cord-022561-rv5j1201	1588	33	lymph	lymph	NN
cord-022561-rv5j1201	1588	34	nodes	node	NNS
cord-022561-rv5j1201	1588	35	and	and	CC
cord-022561-rv5j1201	1588	36	the	the	DT
cord-022561-rv5j1201	1588	37	periarteriolar	periarteriolar	JJ
cord-022561-rv5j1201	1588	38	sheaths	sheath	NNS
cord-022561-rv5j1201	1588	39	of	of	IN
cord-022561-rv5j1201	1588	40	the	the	DT
cord-022561-rv5j1201	1588	41	spleen	spleen	NN
cord-022561-rv5j1201	1588	42	.	.	.
cord-022561-rv5j1201	1589	1	In	in	IN
cord-022561-rv5j1201	1589	2	these	these	DT
cord-022561-rv5j1201	1589	3	specialized	specialized	JJ
cord-022561-rv5j1201	1589	4	sites	site	NNS
cord-022561-rv5j1201	1589	5	,	,	,
cord-022561-rv5j1201	1589	6	the	the	DT
cord-022561-rv5j1201	1589	7	mature	mature	JJ
cord-022561-rv5j1201	1589	8	naïve	naïve	JJ
cord-022561-rv5j1201	1589	9	T	t	NN
cord-022561-rv5j1201	1589	10	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	1589	11	are	be	VBP
cord-022561-rv5j1201	1589	12	activated	activate	VBN
cord-022561-rv5j1201	1589	13	upon	upon	IN
cord-022561-rv5j1201	1589	14	exposure	exposure	NN
cord-022561-rv5j1201	1589	15	to	to	IN
cord-022561-rv5j1201	1589	16	their	-PRON-	PRP$
cord-022561-rv5j1201	1589	17	specific	specific	JJ
cord-022561-rv5j1201	1589	18	antigens	antigen	NNS
cord-022561-rv5j1201	1589	19	and	and	CC
cord-022561-rv5j1201	1589	20	undergo	undergo	VB
cord-022561-rv5j1201	1589	21	additional	additional	JJ
cord-022561-rv5j1201	1589	22	phases	phase	NNS
cord-022561-rv5j1201	1589	23	of	of	IN
cord-022561-rv5j1201	1589	24	development	development	NN
cord-022561-rv5j1201	1589	25	to	to	TO
cord-022561-rv5j1201	1589	26	differentiate	differentiate	VB
cord-022561-rv5j1201	1589	27	into	into	IN
cord-022561-rv5j1201	1589	28	effector	effector	NN
cord-022561-rv5j1201	1589	29	and	and	CC
cord-022561-rv5j1201	1589	30	memory	memory	NN
cord-022561-rv5j1201	1589	31	cells	cell	NNS
cord-022561-rv5j1201	1589	32	.	.	.
cord-022561-rv5j1201	1590	1	The	the	DT
cord-022561-rv5j1201	1590	2	thymus	thymus	NN
cord-022561-rv5j1201	1590	3	attains	attain	VBZ
cord-022561-rv5j1201	1590	4	its	-PRON-	PRP$
cord-022561-rv5j1201	1590	5	maximal	maximal	JJ
cord-022561-rv5j1201	1590	6	mass	mass	NN
cord-022561-rv5j1201	1590	7	relative	relative	NN
cord-022561-rv5j1201	1590	8	to	to	IN
cord-022561-rv5j1201	1590	9	body	body	NN
cord-022561-rv5j1201	1590	10	weight	weight	NN
cord-022561-rv5j1201	1590	11	at	at	IN
cord-022561-rv5j1201	1590	12	birth	birth	NN
cord-022561-rv5j1201	1590	13	and	and	CC
cord-022561-rv5j1201	1590	14	involutes	involute	NNS
cord-022561-rv5j1201	1590	15	after	after	IN
cord-022561-rv5j1201	1590	16	sexual	sexual	JJ
cord-022561-rv5j1201	1590	17	maturity	maturity	NN
cord-022561-rv5j1201	1590	18	;	;	:
cord-022561-rv5j1201	1590	19	the	the	DT
cord-022561-rv5j1201	1590	20	rate	rate	NN
cord-022561-rv5j1201	1590	21	of	of	IN
cord-022561-rv5j1201	1590	22	involution	involution	NN
cord-022561-rv5j1201	1590	23	may	may	MD
cord-022561-rv5j1201	1590	24	vary	vary	VB
cord-022561-rv5j1201	1590	25	among	among	IN
cord-022561-rv5j1201	1590	26	domestic	domestic	JJ
cord-022561-rv5j1201	1590	27	species	specie	NNS
cord-022561-rv5j1201	1590	28	.	.	.
cord-022561-rv5j1201	1591	1	The	the	DT
cord-022561-rv5j1201	1591	2	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	1591	3	and	and	CC
cord-022561-rv5j1201	1591	4	epithelial	epithelial	JJ
cord-022561-rv5j1201	1591	5	components	component	NNS
cord-022561-rv5j1201	1591	6	are	be	VBP
cord-022561-rv5j1201	1591	7	gradually	gradually	RB
cord-022561-rv5j1201	1591	8	replaced	replace	VBN
cord-022561-rv5j1201	1591	9	by	by	IN
cord-022561-rv5j1201	1591	10	loose	loose	JJ
cord-022561-rv5j1201	1591	11	connective	connective	JJ
cord-022561-rv5j1201	1591	12	tissue	tissue	NN
cord-022561-rv5j1201	1591	13	and	and	CC
cord-022561-rv5j1201	1591	14	fat	fat	NN
cord-022561-rv5j1201	1591	15	,	,	,
cord-022561-rv5j1201	1591	16	although	although	IN
cord-022561-rv5j1201	1591	17	remnants	remnant	NNS
cord-022561-rv5j1201	1591	18	remain	remain	VBP
cord-022561-rv5j1201	1591	19	histologically	histologically	RB
cord-022561-rv5j1201	1591	20	,	,	,
cord-022561-rv5j1201	1591	21	even	even	RB
cord-022561-rv5j1201	1591	22	in	in	IN
cord-022561-rv5j1201	1591	23	aged	aged	JJ
cord-022561-rv5j1201	1591	24	animals	animal	NNS
cord-022561-rv5j1201	1591	25	.	.	.
cord-022561-rv5j1201	1592	1	lobule	lobule	NNP
cord-022561-rv5j1201	1592	2	is	be	VBZ
cord-022561-rv5j1201	1592	3	composed	compose	VBN
cord-022561-rv5j1201	1592	4	of	of	IN
cord-022561-rv5j1201	1592	5	a	a	DT
cord-022561-rv5j1201	1592	6	central	central	JJ
cord-022561-rv5j1201	1592	7	medulla	medulla	NN
cord-022561-rv5j1201	1592	8	and	and	CC
cord-022561-rv5j1201	1592	9	surrounding	surround	VBG
cord-022561-rv5j1201	1592	10	cortex	cortex	NN
cord-022561-rv5j1201	1593	1	(	(	-LRB-
cord-022561-rv5j1201	1593	2	Fig	Fig	NNP
cord-022561-rv5j1201	1593	3	.	.	.
cord-022561-rv5j1201	1593	4	 	 	_SP
cord-022561-rv5j1201	1593	5	13	13	CD
cord-022561-rv5j1201	1593	6	-	-	SYM
cord-022561-rv5j1201	1593	7	36	36	CD
cord-022561-rv5j1201	1593	8	)	)	-RRB-
cord-022561-rv5j1201	1593	9	.	.	.
cord-022561-rv5j1201	1594	1	The	the	DT
cord-022561-rv5j1201	1594	2	thymic	thymic	JJ
cord-022561-rv5j1201	1594	3	cortex	cortex	NN
cord-022561-rv5j1201	1594	4	consists	consist	VBZ
cord-022561-rv5j1201	1594	5	mainly	mainly	RB
cord-022561-rv5j1201	1594	6	of	of	IN
cord-022561-rv5j1201	1594	7	an	an	DT
cord-022561-rv5j1201	1594	8	epithelial	epithelial	JJ
cord-022561-rv5j1201	1594	9	reticulum	reticulum	NN
cord-022561-rv5j1201	1594	10	and	and	CC
cord-022561-rv5j1201	1594	11	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	1595	1	(	(	-LRB-
cord-022561-rv5j1201	1595	2	Fig	Fig	NNP
cord-022561-rv5j1201	1595	3	.	.	NNP
cord-022561-rv5j1201	1595	4	13	13	CD
cord-022561-rv5j1201	1595	5	-	-	SYM
cord-022561-rv5j1201	1595	6	37	37	CD
cord-022561-rv5j1201	1595	7	)	)	-RRB-
cord-022561-rv5j1201	1595	8	.	.	.
cord-022561-rv5j1201	1596	1	The	the	DT
cord-022561-rv5j1201	1596	2	stellate	stellate	JJ
cord-022561-rv5j1201	1596	3	cells	cell	NNS
cord-022561-rv5j1201	1596	4	of	of	IN
cord-022561-rv5j1201	1596	5	the	the	DT
cord-022561-rv5j1201	1596	6	epithelial	epithelial	JJ
cord-022561-rv5j1201	1596	7	reticulum	reticulum	NN
cord-022561-rv5j1201	1596	8	have	have	VBP
cord-022561-rv5j1201	1596	9	elongate	elongate	RB
cord-022561-rv5j1201	1596	10	branching	branch	VBG
cord-022561-rv5j1201	1596	11	cytoplasmic	cytoplasmic	JJ
cord-022561-rv5j1201	1596	12	processes	process	NNS
cord-022561-rv5j1201	1596	13	that	that	WDT
cord-022561-rv5j1201	1596	14	connect	connect	VBP
cord-022561-rv5j1201	1596	15	to	to	IN
cord-022561-rv5j1201	1596	16	adjacent	adjacent	JJ
cord-022561-rv5j1201	1596	17	epithelial	epithelial	JJ
cord-022561-rv5j1201	1596	18	cells	cell	NNS
cord-022561-rv5j1201	1596	19	through	through	IN
cord-022561-rv5j1201	1596	20	desmosomes	desmosome	NNS
cord-022561-rv5j1201	1596	21	,	,	,
cord-022561-rv5j1201	1596	22	thus	thus	RB
cord-022561-rv5j1201	1596	23	forming	form	VBG
cord-022561-rv5j1201	1596	24	a	a	DT
cord-022561-rv5j1201	1596	25	supportive	supportive	JJ
cord-022561-rv5j1201	1596	26	network	network	NN
cord-022561-rv5j1201	1596	27	(	(	-LRB-
cord-022561-rv5j1201	1596	28	cytoreticulum	cytoreticulum	NNP
cord-022561-rv5j1201	1596	29	)	)	-RRB-
cord-022561-rv5j1201	1596	30	.	.	.
cord-022561-rv5j1201	1597	1	The	the	DT
cord-022561-rv5j1201	1597	2	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	1597	3	component	component	NN
cord-022561-rv5j1201	1597	4	is	be	VBZ
cord-022561-rv5j1201	1597	5	composed	compose	VBN
cord-022561-rv5j1201	1597	6	of	of	IN
cord-022561-rv5j1201	1597	7	differentiating	differentiate	VBG
cord-022561-rv5j1201	1597	8	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	1597	9	derived	derive	VBN
cord-022561-rv5j1201	1597	10	from	from	IN
cord-022561-rv5j1201	1597	11	progenitor	progenitor	NN
cord-022561-rv5j1201	1597	12	(	(	-LRB-
cord-022561-rv5j1201	1597	13	also	also	RB
cord-022561-rv5j1201	1597	14	known	know	VBN
cord-022561-rv5j1201	1597	15	as	as	IN
cord-022561-rv5j1201	1597	16	precursor	precursor	NN
cord-022561-rv5j1201	1597	17	)	)	-RRB-
cord-022561-rv5j1201	1597	18	T	t	NN
cord-022561-rv5j1201	1597	19	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	1597	20	in	in	IN
cord-022561-rv5j1201	1597	21	the	the	DT
cord-022561-rv5j1201	1597	22	bone	bone	NN
cord-022561-rv5j1201	1597	23	marrow	marrow	NN
cord-022561-rv5j1201	1597	24	.	.	.
cord-022561-rv5j1201	1598	1	The	the	DT
cord-022561-rv5j1201	1598	2	medulla	medulla	NN
cord-022561-rv5j1201	1598	3	is	be	VBZ
cord-022561-rv5j1201	1598	4	composed	compose	VBN
cord-022561-rv5j1201	1598	5	of	of	IN
cord-022561-rv5j1201	1598	6	similar	similar	JJ
cord-022561-rv5j1201	1598	7	epithelial	epithelial	JJ
cord-022561-rv5j1201	1598	8	reticular	reticular	JJ
cord-022561-rv5j1201	1598	9	cells	cell	NNS
cord-022561-rv5j1201	1598	10	,	,	,
cord-022561-rv5j1201	1598	11	many	many	JJ
cord-022561-rv5j1201	1598	12	of	of	IN
cord-022561-rv5j1201	1598	13	which	which	WDT
cord-022561-rv5j1201	1598	14	are	be	VBP
cord-022561-rv5j1201	1598	15	much	much	RB
cord-022561-rv5j1201	1598	16	larger	large	JJR
cord-022561-rv5j1201	1598	17	than	than	IN
cord-022561-rv5j1201	1598	18	those	those	DT
cord-022561-rv5j1201	1598	19	in	in	IN
cord-022561-rv5j1201	1598	20	the	the	DT
cord-022561-rv5j1201	1598	21	cortex	cortex	NN
cord-022561-rv5j1201	1598	22	and	and	CC
cord-022561-rv5j1201	1598	23	have	have	VBP
cord-022561-rv5j1201	1598	24	a	a	DT
cord-022561-rv5j1201	1598	25	more	more	RBR
cord-022561-rv5j1201	1598	26	obvious	obvious	JJ
cord-022561-rv5j1201	1598	27	epithelial	epithelial	JJ
cord-022561-rv5j1201	1598	28	structure	structure	NN
cord-022561-rv5j1201	1598	29	.	.	.
cord-022561-rv5j1201	1599	1	Some	some	DT
cord-022561-rv5j1201	1599	2	of	of	IN
cord-022561-rv5j1201	1599	3	the	the	DT
cord-022561-rv5j1201	1599	4	epithelial	epithelial	JJ
cord-022561-rv5j1201	1599	5	reticular	reticular	JJ
cord-022561-rv5j1201	1599	6	cells	cell	NNS
cord-022561-rv5j1201	1599	7	form	form	VBP
cord-022561-rv5j1201	1599	8	thymic	thymic	JJ
cord-022561-rv5j1201	1599	9	corpuscles	corpuscle	NNS
cord-022561-rv5j1201	1599	10	,	,	,
cord-022561-rv5j1201	1599	11	also	also	RB
cord-022561-rv5j1201	1599	12	called	call	VBN
cord-022561-rv5j1201	1599	13	Hassall	Hassall	NNP
cord-022561-rv5j1201	1599	14	's	's	POS
cord-022561-rv5j1201	1599	15	corpuscles	corpuscle	NNS
cord-022561-rv5j1201	1599	16	,	,	,
cord-022561-rv5j1201	1599	17	which	which	WDT
cord-022561-rv5j1201	1599	18	are	be	VBP
cord-022561-rv5j1201	1599	19	distinctive	distinctive	JJ
cord-022561-rv5j1201	1599	20	keratinized	keratinized	JJ
cord-022561-rv5j1201	1599	21	epithelial	epithelial	JJ
cord-022561-rv5j1201	1599	22	structures	structure	NNS
cord-022561-rv5j1201	1599	23	(	(	-LRB-
cord-022561-rv5j1201	1599	24	see	see	VB
cord-022561-rv5j1201	1599	25	Fig	Fig	NNP
cord-022561-rv5j1201	1599	26	.	.	.
cord-022561-rv5j1201	1600	1	13	13	CD
cord-022561-rv5j1201	1600	2	-	-	SYM
cord-022561-rv5j1201	1600	3	37	37	CD
cord-022561-rv5j1201	1600	4	)	)	-RRB-
cord-022561-rv5j1201	1600	5	.	.	.
cord-022561-rv5j1201	1601	1	Interdigitating	Interdigitating	NNP
cord-022561-rv5j1201	1601	2	dendritic	dendritic	JJ
cord-022561-rv5j1201	1601	3	cells	cell	NNS
cord-022561-rv5j1201	1601	4	(	(	-LRB-
cord-022561-rv5j1201	1601	5	DCs	DCs	NNP
cord-022561-rv5j1201	1601	6	)	)	-RRB-
cord-022561-rv5j1201	1601	7	are	be	VBP
cord-022561-rv5j1201	1601	8	also	also	RB
cord-022561-rv5j1201	1601	9	present	present	JJ
cord-022561-rv5j1201	1601	10	within	within	IN
cord-022561-rv5j1201	1601	11	the	the	DT
cord-022561-rv5j1201	1601	12	medulla	medulla	NN
cord-022561-rv5j1201	1601	13	,	,	,
cord-022561-rv5j1201	1601	14	but	but	CC
cord-022561-rv5j1201	1601	15	there	there	EX
cord-022561-rv5j1201	1601	16	are	be	VBP
cord-022561-rv5j1201	1601	17	far	far	RB
cord-022561-rv5j1201	1601	18	fewer	few	JJR
cord-022561-rv5j1201	1601	19	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	1601	20	than	than	IN
cord-022561-rv5j1201	1601	21	in	in	IN
cord-022561-rv5j1201	1601	22	the	the	DT
cord-022561-rv5j1201	1601	23	cortex	cortex	NN
cord-022561-rv5j1201	1601	24	.	.	.
cord-022561-rv5j1201	1602	1	The	the	DT
cord-022561-rv5j1201	1602	2	progenitor	progenitor	NN
cord-022561-rv5j1201	1602	3	T	t	NN
cord-022561-rv5j1201	1602	4	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	1602	5	released	release	VBN
cord-022561-rv5j1201	1602	6	from	from	IN
cord-022561-rv5j1201	1602	7	the	the	DT
cord-022561-rv5j1201	1602	8	bone	bone	NN
cord-022561-rv5j1201	1602	9	marrow	marrow	NN
cord-022561-rv5j1201	1602	10	into	into	IN
cord-022561-rv5j1201	1602	11	the	the	DT
cord-022561-rv5j1201	1602	12	blood	blood	NN
cord-022561-rv5j1201	1602	13	enter	enter	VBP
cord-022561-rv5j1201	1602	14	the	the	DT
cord-022561-rv5j1201	1602	15	thymus	thymus	NN
cord-022561-rv5j1201	1602	16	in	in	IN
cord-022561-rv5j1201	1602	17	the	the	DT
cord-022561-rv5j1201	1602	18	subcapsular	subcapsular	NNP
cord-022561-rv5j1201	1602	19	zone	zone	NNP
cord-022561-rv5j1201	1602	20	of	of	IN
cord-022561-rv5j1201	1602	21	the	the	DT
cord-022561-rv5j1201	1602	22	cortex	cortex	NN
cord-022561-rv5j1201	1602	23	and	and	CC
cord-022561-rv5j1201	1602	24	begin	begin	VB
cord-022561-rv5j1201	1602	25	the	the	DT
cord-022561-rv5j1201	1602	26	differentiation	differentiation	NN
cord-022561-rv5j1201	1602	27	and	and	CC
cord-022561-rv5j1201	1602	28	selection	selection	NN
cord-022561-rv5j1201	1602	29	processes	process	NNS
cord-022561-rv5j1201	1602	30	,	,	,
cord-022561-rv5j1201	1602	31	developing	develop	VBG
cord-022561-rv5j1201	1602	32	into	into	IN
cord-022561-rv5j1201	1602	33	mature	mature	JJ
cord-022561-rv5j1201	1602	34	naïve	naïve	JJ
cord-022561-rv5j1201	1602	35	T	t	NN
cord-022561-rv5j1201	1602	36	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	1602	37	as	as	IN
cord-022561-rv5j1201	1602	38	they	-PRON-	PRP
cord-022561-rv5j1201	1602	39	traverse	traverse	VBP
cord-022561-rv5j1201	1602	40	the	the	DT
cord-022561-rv5j1201	1602	41	thymic	thymic	JJ
cord-022561-rv5j1201	1602	42	cortex	cortex	NN
cord-022561-rv5j1201	1602	43	to	to	IN
cord-022561-rv5j1201	1602	44	the	the	DT
cord-022561-rv5j1201	1602	45	medulla	medulla	NN
cord-022561-rv5j1201	1602	46	.	.	.
cord-022561-rv5j1201	1603	1	In	in	IN
cord-022561-rv5j1201	1603	2	the	the	DT
cord-022561-rv5j1201	1603	3	cortex	cortex	NN
cord-022561-rv5j1201	1603	4	,	,	,
cord-022561-rv5j1201	1603	5	T	t	NN
cord-022561-rv5j1201	1603	6	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	1603	7	that	that	WDT
cord-022561-rv5j1201	1603	8	recognize	recognize	VBP
cord-022561-rv5j1201	1603	9	self	self	NN
cord-022561-rv5j1201	1603	10	-	-	HYPH
cord-022561-rv5j1201	1603	11	molecules	molecule	NNS
cord-022561-rv5j1201	1603	12	(	(	-LRB-
cord-022561-rv5j1201	1603	13	major	major	JJ
cord-022561-rv5j1201	1603	14	histocompatibility	histocompatibility	NN
cord-022561-rv5j1201	1603	15	complex	complex	NN
cord-022561-rv5j1201	1603	16	[	[	-LRB-
cord-022561-rv5j1201	1603	17	MHC	MHC	NNP
cord-022561-rv5j1201	1603	18	]	]	-RRB-
cord-022561-rv5j1201	1603	19	 	 	_SP
cord-022561-rv5j1201	1604	1	The	the	DT
cord-022561-rv5j1201	1604	2	responses	response	NNS
cord-022561-rv5j1201	1604	3	of	of	IN
cord-022561-rv5j1201	1604	4	the	the	DT
cord-022561-rv5j1201	1604	5	thymus	thymus	NN
cord-022561-rv5j1201	1604	6	to	to	IN
cord-022561-rv5j1201	1604	7	injury	injury	NN
cord-022561-rv5j1201	1604	8	and	and	CC
cord-022561-rv5j1201	1604	9	causes	cause	NNS
cord-022561-rv5j1201	1604	10	are	be	VBP
cord-022561-rv5j1201	1604	11	listed	list	VBN
cord-022561-rv5j1201	1604	12	in	in	IN
cord-022561-rv5j1201	1604	13	Boxes	Boxes	NNP
cord-022561-rv5j1201	1604	14	13	13	CD
cord-022561-rv5j1201	1604	15	-	-	SYM
cord-022561-rv5j1201	1604	16	4	4	CD
cord-022561-rv5j1201	1604	17	and	and	CC
cord-022561-rv5j1201	1604	18	13	13	CD
cord-022561-rv5j1201	1604	19	-	-	SYM
cord-022561-rv5j1201	1604	20	5	5	CD
cord-022561-rv5j1201	1604	21	.	.	.
cord-022561-rv5j1201	1605	1	The	the	DT
cord-022561-rv5j1201	1605	2	most	most	RBS
cord-022561-rv5j1201	1605	3	common	common	JJ
cord-022561-rv5j1201	1605	4	change	change	NN
cord-022561-rv5j1201	1605	5	is	be	VBZ
cord-022561-rv5j1201	1605	6	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	1605	7	atrophy	atrophy	NN
cord-022561-rv5j1201	1605	8	caused	cause	VBN
cord-022561-rv5j1201	1605	9	by	by	IN
cord-022561-rv5j1201	1605	10	physical	physical	JJ
cord-022561-rv5j1201	1605	11	and	and	CC
cord-022561-rv5j1201	1605	12	physiologic	physiologic	JJ
cord-022561-rv5j1201	1605	13	stresses	stress	NNS
cord-022561-rv5j1201	1605	14	,	,	,
cord-022561-rv5j1201	1605	15	toxins	toxin	NNS
cord-022561-rv5j1201	1605	16	,	,	,
cord-022561-rv5j1201	1605	17	drugs	drug	NNS
cord-022561-rv5j1201	1605	18	,	,	,
cord-022561-rv5j1201	1605	19	and	and	CC
cord-022561-rv5j1201	1605	20	viral	viral	JJ
cord-022561-rv5j1201	1605	21	infections	infection	NNS
cord-022561-rv5j1201	1605	22	.	.	.
cord-022561-rv5j1201	1606	1	Atrophy	atrophy	NN
cord-022561-rv5j1201	1606	2	.	.	.
cord-022561-rv5j1201	1607	1	Because	because	IN
cord-022561-rv5j1201	1607	2	the	the	DT
cord-022561-rv5j1201	1607	3	thymus	thymus	NN
cord-022561-rv5j1201	1607	4	does	do	VBZ
cord-022561-rv5j1201	1607	5	not	not	RB
cord-022561-rv5j1201	1607	6	contain	contain	VB
cord-022561-rv5j1201	1607	7	any	any	DT
cord-022561-rv5j1201	1607	8	lymphopoietic	lymphopoietic	JJ
cord-022561-rv5j1201	1607	9	tissue	tissue	NN
cord-022561-rv5j1201	1607	10	,	,	,
cord-022561-rv5j1201	1607	11	it	-PRON-	PRP
cord-022561-rv5j1201	1607	12	depends	depend	VBZ
cord-022561-rv5j1201	1607	13	on	on	IN
cord-022561-rv5j1201	1607	14	the	the	DT
cord-022561-rv5j1201	1607	15	bone	bone	NN
cord-022561-rv5j1201	1607	16	marrow	marrow	NN
cord-022561-rv5j1201	1607	17	for	for	IN
cord-022561-rv5j1201	1607	18	the	the	DT
cord-022561-rv5j1201	1607	19	supply	supply	NN
cord-022561-rv5j1201	1607	20	of	of	IN
cord-022561-rv5j1201	1607	21	progenitor	progenitor	NN
cord-022561-rv5j1201	1607	22	T	t	NN
cord-022561-rv5j1201	1607	23	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	1607	24	.	.	.
cord-022561-rv5j1201	1608	1	Thus	thus	RB
cord-022561-rv5j1201	1608	2	thymic	thymic	JJ
cord-022561-rv5j1201	1608	3	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	1608	4	atrophy	atrophy	NN
cord-022561-rv5j1201	1608	5	can	can	MD
cord-022561-rv5j1201	1608	6	be	be	VB
cord-022561-rv5j1201	1608	7	the	the	DT
cord-022561-rv5j1201	1608	8	result	result	NN
cord-022561-rv5j1201	1608	9	of	of	IN
cord-022561-rv5j1201	1608	10	either	either	CC
cord-022561-rv5j1201	1608	11	an	an	DT
cord-022561-rv5j1201	1608	12	inadequate	inadequate	JJ
cord-022561-rv5j1201	1608	13	supply	supply	NN
cord-022561-rv5j1201	1608	14	of	of	IN
cord-022561-rv5j1201	1608	15	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	1608	16	from	from	IN
cord-022561-rv5j1201	1608	17	the	the	DT
cord-022561-rv5j1201	1608	18	bone	bone	NN
cord-022561-rv5j1201	1608	19	marrow	marrow	NN
cord-022561-rv5j1201	1608	20	or	or	CC
cord-022561-rv5j1201	1608	21	lysis	lysis	NN
cord-022561-rv5j1201	1608	22	of	of	IN
cord-022561-rv5j1201	1608	23	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	1608	24	(	(	-LRB-
cord-022561-rv5j1201	1608	25	lymphocytolysis	lymphocytolysis	NNP
cord-022561-rv5j1201	1608	26	)	)	-RRB-
cord-022561-rv5j1201	1608	27	in	in	IN
cord-022561-rv5j1201	1608	28	the	the	DT
cord-022561-rv5j1201	1608	29	thymus	thymus	NN
cord-022561-rv5j1201	1608	30	.	.	.
cord-022561-rv5j1201	1609	1	Thymic	Thymic	NNP
cord-022561-rv5j1201	1609	2	aims	aim	VBZ
cord-022561-rv5j1201	1609	3	to	to	TO
cord-022561-rv5j1201	1609	4	define	define	VB
cord-022561-rv5j1201	1609	5	the	the	DT
cord-022561-rv5j1201	1609	6	terms	term	NNS
cord-022561-rv5j1201	1609	7	used	use	VBN
cord-022561-rv5j1201	1609	8	in	in	IN
cord-022561-rv5j1201	1609	9	this	this	DT
cord-022561-rv5j1201	1609	10	chapter	chapter	NN
cord-022561-rv5j1201	1609	11	.	.	.
cord-022561-rv5j1201	1610	1	The	the	DT
cord-022561-rv5j1201	1610	2	term	term	NN
cord-022561-rv5j1201	1610	3	splenic	splenic	JJ
cord-022561-rv5j1201	1610	4	sinusoid	sinusoid	NN
cord-022561-rv5j1201	1610	5	is	be	VBZ
cord-022561-rv5j1201	1610	6	used	use	VBN
cord-022561-rv5j1201	1610	7	to	to	TO
cord-022561-rv5j1201	1610	8	describe	describe	VB
cord-022561-rv5j1201	1610	9	a	a	DT
cord-022561-rv5j1201	1610	10	vascular	vascular	JJ
cord-022561-rv5j1201	1610	11	structure	structure	NN
cord-022561-rv5j1201	1610	12	present	present	JJ
cord-022561-rv5j1201	1610	13	in	in	IN
cord-022561-rv5j1201	1610	14	the	the	DT
cord-022561-rv5j1201	1610	15	sinusal	sinusal	NN
cord-022561-rv5j1201	1610	16	spleen	spleen	NNS
cord-022561-rv5j1201	1610	17	(	(	-LRB-
cord-022561-rv5j1201	1610	18	also	also	RB
cord-022561-rv5j1201	1610	19	known	know	VBN
cord-022561-rv5j1201	1610	20	as	as	IN
cord-022561-rv5j1201	1610	21	sinusoidal	sinusoidal	JJ
cord-022561-rv5j1201	1610	22	spleen	spleen	NN
cord-022561-rv5j1201	1610	23	)	)	-RRB-
cord-022561-rv5j1201	1610	24	;	;	:
cord-022561-rv5j1201	1610	25	dogs	dog	NNS
cord-022561-rv5j1201	1610	26	are	be	VBP
cord-022561-rv5j1201	1610	27	the	the	DT
cord-022561-rv5j1201	1610	28	only	only	JJ
cord-022561-rv5j1201	1610	29	domestic	domestic	JJ
cord-022561-rv5j1201	1610	30	animal	animal	NN
cord-022561-rv5j1201	1610	31	with	with	IN
cord-022561-rv5j1201	1610	32	true	true	JJ
cord-022561-rv5j1201	1610	33	splenic	splenic	JJ
cord-022561-rv5j1201	1610	34	sinusoids	sinusoid	NNS
cord-022561-rv5j1201	1610	35	.	.	.
cord-022561-rv5j1201	1611	1	The	the	DT
cord-022561-rv5j1201	1611	2	term	term	NN
cord-022561-rv5j1201	1611	3	red	red	JJ
cord-022561-rv5j1201	1611	4	pulp	pulp	NN
cord-022561-rv5j1201	1611	5	vascular	vascular	JJ
cord-022561-rv5j1201	1611	6	spaces	space	NNS
cord-022561-rv5j1201	1611	7	is	be	VBZ
cord-022561-rv5j1201	1611	8	used	use	VBN
cord-022561-rv5j1201	1611	9	(	(	-LRB-
cord-022561-rv5j1201	1611	10	as	as	IN
cord-022561-rv5j1201	1611	11	opposed	oppose	VBN
cord-022561-rv5j1201	1611	12	to	to	IN
cord-022561-rv5j1201	1611	13	"	"	``
cord-022561-rv5j1201	1611	14	sinus	sinus	NN
cord-022561-rv5j1201	1611	15	"	"	''
cord-022561-rv5j1201	1611	16	)	)	-RRB-
cord-022561-rv5j1201	1611	17	to	to	TO
cord-022561-rv5j1201	1611	18	describe	describe	VB
cord-022561-rv5j1201	1611	19	the	the	DT
cord-022561-rv5j1201	1611	20	vascular	vascular	JJ
cord-022561-rv5j1201	1611	21	spaces	space	NNS
cord-022561-rv5j1201	1611	22	in	in	IN
cord-022561-rv5j1201	1611	23	the	the	DT
cord-022561-rv5j1201	1611	24	red	red	JJ
cord-022561-rv5j1201	1611	25	pulp	pulp	NN
cord-022561-rv5j1201	1611	26	of	of	IN
cord-022561-rv5j1201	1611	27	both	both	CC
cord-022561-rv5j1201	1611	28	the	the	DT
cord-022561-rv5j1201	1611	29	nonsinusal	nonsinusal	NN
cord-022561-rv5j1201	1611	30	and	and	CC
cord-022561-rv5j1201	1611	31	nonsinusoidal	nonsinusoidal	JJ
cord-022561-rv5j1201	1611	32	spleens	spleen	NNS
cord-022561-rv5j1201	1611	33	of	of	IN
cord-022561-rv5j1201	1611	34	all	all	DT
cord-022561-rv5j1201	1611	35	domestic	domestic	JJ
cord-022561-rv5j1201	1611	36	animals	animal	NNS
cord-022561-rv5j1201	1611	37	.	.	.
cord-022561-rv5j1201	1612	1	4	4	LS
cord-022561-rv5j1201	1613	1	The	the	DT
cord-022561-rv5j1201	1613	2	other	other	JJ
cord-022561-rv5j1201	1613	3	terms	term	NNS
cord-022561-rv5j1201	1613	4	used	use	VBN
cord-022561-rv5j1201	1613	5	here	here	RB
cord-022561-rv5j1201	1613	6	include	include	VBP
cord-022561-rv5j1201	1613	7	marginal	marginal	JJ
cord-022561-rv5j1201	1613	8	sinus	sinus	NN
cord-022561-rv5j1201	1613	9	,	,	,
cord-022561-rv5j1201	1613	10	marginal	marginal	JJ
cord-022561-rv5j1201	1613	11	zone	zone	NN
cord-022561-rv5j1201	1613	12	,	,	,
cord-022561-rv5j1201	1613	13	periarteriolar	periarteriolar	JJ
cord-022561-rv5j1201	1613	14	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	1613	15	sheath	sheath	NN
cord-022561-rv5j1201	1613	16	(	(	-LRB-
cord-022561-rv5j1201	1613	17	PALS	PALS	NNP
cord-022561-rv5j1201	1613	18	)	)	-RRB-
cord-022561-rv5j1201	1613	19	,	,	,
cord-022561-rv5j1201	1613	20	periarteriolar	periarteriolar	NNP
cord-022561-rv5j1201	1613	21	macrophage	macrophage	NN
cord-022561-rv5j1201	1613	22	sheath	sheath	NN
cord-022561-rv5j1201	1613	23	(	(	-LRB-
cord-022561-rv5j1201	1613	24	PAMS	PAMS	NNP
cord-022561-rv5j1201	1613	25	)	)	-RRB-
cord-022561-rv5j1201	1613	26	,	,	,
cord-022561-rv5j1201	1613	27	and	and	CC
cord-022561-rv5j1201	1613	28	splenic	splenic	JJ
cord-022561-rv5j1201	1613	29	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	1613	30	follicles	follicle	NNS
cord-022561-rv5j1201	1613	31	.	.	.
cord-022561-rv5j1201	1614	1	The	the	DT
cord-022561-rv5j1201	1614	2	spleen	spleen	NN
cord-022561-rv5j1201	1614	3	is	be	VBZ
cord-022561-rv5j1201	1614	4	located	locate	VBN
cord-022561-rv5j1201	1614	5	in	in	IN
cord-022561-rv5j1201	1614	6	the	the	DT
cord-022561-rv5j1201	1614	7	left	left	JJ
cord-022561-rv5j1201	1614	8	cranial	cranial	JJ
cord-022561-rv5j1201	1614	9	hypogastric	hypogastric	JJ
cord-022561-rv5j1201	1614	10	region	region	NN
cord-022561-rv5j1201	1614	11	of	of	IN
cord-022561-rv5j1201	1614	12	the	the	DT
cord-022561-rv5j1201	1614	13	abdomen	abdomen	NN
cord-022561-rv5j1201	1614	14	,	,	,
cord-022561-rv5j1201	1614	15	where	where	WRB
cord-022561-rv5j1201	1614	16	it	-PRON-	PRP
cord-022561-rv5j1201	1614	17	is	be	VBZ
cord-022561-rv5j1201	1614	18	typically	typically	RB
cord-022561-rv5j1201	1614	19	suspended	suspend	VBN
cord-022561-rv5j1201	1614	20	in	in	IN
cord-022561-rv5j1201	1614	21	the	the	DT
cord-022561-rv5j1201	1614	22	gastrosplenic	gastrosplenic	NNP
cord-022561-rv5j1201	1614	23	ligament	ligament	NN
cord-022561-rv5j1201	1614	24	between	between	IN
cord-022561-rv5j1201	1614	25	the	the	DT
cord-022561-rv5j1201	1614	26	diaphragm	diaphragm	NN
cord-022561-rv5j1201	1614	27	,	,	,
cord-022561-rv5j1201	1614	28	stomach	stomach	NN
cord-022561-rv5j1201	1614	29	,	,	,
cord-022561-rv5j1201	1614	30	and	and	CC
cord-022561-rv5j1201	1614	31	the	the	DT
cord-022561-rv5j1201	1614	32	body	body	NN
cord-022561-rv5j1201	1614	33	wall	wall	NN
cord-022561-rv5j1201	1614	34	.	.	.
cord-022561-rv5j1201	1615	1	The	the	DT
cord-022561-rv5j1201	1615	2	exception	exception	NN
cord-022561-rv5j1201	1615	3	is	be	VBZ
cord-022561-rv5j1201	1615	4	in	in	IN
cord-022561-rv5j1201	1615	5	domestic	domestic	JJ
cord-022561-rv5j1201	1615	6	ruminants	ruminant	NNS
cord-022561-rv5j1201	1615	7	,	,	,
cord-022561-rv5j1201	1615	8	where	where	WRB
cord-022561-rv5j1201	1615	9	it	-PRON-	PRP
cord-022561-rv5j1201	1615	10	is	be	VBZ
cord-022561-rv5j1201	1615	11	closely	closely	RB
cord-022561-rv5j1201	1615	12	adhered	adhere	VBN
cord-022561-rv5j1201	1615	13	to	to	IN
cord-022561-rv5j1201	1615	14	the	the	DT
cord-022561-rv5j1201	1615	15	left	left	JJ
cord-022561-rv5j1201	1615	16	dorsolateral	dorsolateral	JJ
cord-022561-rv5j1201	1615	17	aspect	aspect	NN
cord-022561-rv5j1201	1615	18	of	of	IN
cord-022561-rv5j1201	1615	19	the	the	DT
cord-022561-rv5j1201	1615	20	rumen	rumen	NN
cord-022561-rv5j1201	1615	21	.	.	.
cord-022561-rv5j1201	1616	1	The	the	DT
cord-022561-rv5j1201	1616	2	gross	gross	JJ
cord-022561-rv5j1201	1616	3	shape	shape	NN
cord-022561-rv5j1201	1616	4	and	and	CC
cord-022561-rv5j1201	1616	5	size	size	NN
cord-022561-rv5j1201	1616	6	of	of	IN
cord-022561-rv5j1201	1616	7	the	the	DT
cord-022561-rv5j1201	1616	8	spleen	spleen	NNS
cord-022561-rv5j1201	1616	9	vary	vary	VBP
cord-022561-rv5j1201	1616	10	markedly	markedly	RB
cord-022561-rv5j1201	1616	11	among	among	IN
cord-022561-rv5j1201	1616	12	domestic	domestic	JJ
cord-022561-rv5j1201	1616	13	animals	animal	NNS
cord-022561-rv5j1201	1616	14	,	,	,
cord-022561-rv5j1201	1616	15	but	but	CC
cord-022561-rv5j1201	1616	16	generally	generally	RB
cord-022561-rv5j1201	1616	17	it	-PRON-	PRP
cord-022561-rv5j1201	1616	18	is	be	VBZ
cord-022561-rv5j1201	1616	19	a	a	DT
cord-022561-rv5j1201	1616	20	flattened	flatten	VBN
cord-022561-rv5j1201	1616	21	,	,	,
cord-022561-rv5j1201	1616	22	elongated	elongated	JJ
cord-022561-rv5j1201	1616	23	organ	organ	NN
cord-022561-rv5j1201	1616	24	.	.	.
cord-022561-rv5j1201	1617	1	Some	some	DT
cord-022561-rv5j1201	1617	2	species	specie	NNS
cord-022561-rv5j1201	1617	3	,	,	,
cord-022561-rv5j1201	1617	4	notably	notably	RB
cord-022561-rv5j1201	1617	5	birds	bird	NNS
cord-022561-rv5j1201	1617	6	,	,	,
cord-022561-rv5j1201	1617	7	demonstrate	demonstrate	VB
cord-022561-rv5j1201	1617	8	seasonal	seasonal	JJ
cord-022561-rv5j1201	1617	9	variation	variation	NN
cord-022561-rv5j1201	1617	10	in	in	IN
cord-022561-rv5j1201	1617	11	splenic	splenic	JJ
cord-022561-rv5j1201	1617	12	shape	shape	NN
cord-022561-rv5j1201	1617	13	and	and	CC
cord-022561-rv5j1201	1617	14	size	size	NN
cord-022561-rv5j1201	1617	15	.	.	.
cord-022561-rv5j1201	1618	1	The	the	DT
cord-022561-rv5j1201	1618	2	spleen	spleen	NN
cord-022561-rv5j1201	1618	3	is	be	VBZ
cord-022561-rv5j1201	1618	4	covered	cover	VBN
cord-022561-rv5j1201	1618	5	by	by	IN
cord-022561-rv5j1201	1618	6	a	a	DT
cord-022561-rv5j1201	1618	7	thick	thick	JJ
cord-022561-rv5j1201	1618	8	capsule	capsule	NN
cord-022561-rv5j1201	1618	9	composed	compose	VBN
cord-022561-rv5j1201	1618	10	of	of	IN
cord-022561-rv5j1201	1618	11	smooth	smooth	JJ
cord-022561-rv5j1201	1618	12	muscle	muscle	NN
cord-022561-rv5j1201	1618	13	and	and	CC
cord-022561-rv5j1201	1618	14	elastic	elastic	JJ
cord-022561-rv5j1201	1618	15	fibers	fiber	NNS
cord-022561-rv5j1201	1618	16	,	,	,
cord-022561-rv5j1201	1618	17	from	from	IN
cord-022561-rv5j1201	1618	18	which	which	WDT
cord-022561-rv5j1201	1618	19	numerous	numerous	JJ
cord-022561-rv5j1201	1618	20	intertwining	intertwine	VBG
cord-022561-rv5j1201	1618	21	fibromuscular	fibromuscular	JJ
cord-022561-rv5j1201	1618	22	trabeculae	trabeculae	NNP
cord-022561-rv5j1201	1618	23	extend	extend	VBP
cord-022561-rv5j1201	1618	24	into	into	IN
cord-022561-rv5j1201	1618	25	the	the	DT
cord-022561-rv5j1201	1618	26	parenchyma	parenchyma	NN
cord-022561-rv5j1201	1618	27	.	.	.
cord-022561-rv5j1201	1619	1	These	these	DT
cord-022561-rv5j1201	1619	2	trabeculae	trabeculae	NNP
cord-022561-rv5j1201	1619	3	and	and	CC
cord-022561-rv5j1201	1619	4	reticular	reticular	JJ
cord-022561-rv5j1201	1619	5	cells	cell	NNS
cord-022561-rv5j1201	1619	6	form	form	VBP
cord-022561-rv5j1201	1619	7	a	a	DT
cord-022561-rv5j1201	1619	8	spongelike	spongelike	JJ
cord-022561-rv5j1201	1619	9	supportive	supportive	JJ
cord-022561-rv5j1201	1619	10	matrix	matrix	NN
cord-022561-rv5j1201	1619	11	for	for	IN
cord-022561-rv5j1201	1619	12	the	the	DT
cord-022561-rv5j1201	1619	13	parenchyma	parenchyma	NN
cord-022561-rv5j1201	1619	14	of	of	IN
cord-022561-rv5j1201	1619	15	the	the	DT
cord-022561-rv5j1201	1619	16	mammalian	mammalian	JJ
cord-022561-rv5j1201	1619	17	spleen	spleen	NNS
cord-022561-rv5j1201	1619	18	in	in	IN
cord-022561-rv5j1201	1619	19	all	all	DT
cord-022561-rv5j1201	1619	20	domestic	domestic	JJ
cord-022561-rv5j1201	1619	21	species	specie	NNS
cord-022561-rv5j1201	1619	22	.	.	.
cord-022561-rv5j1201	1620	1	In	in	IN
cord-022561-rv5j1201	1620	2	cattle	cattle	NNS
cord-022561-rv5j1201	1620	3	and	and	CC
cord-022561-rv5j1201	1620	4	horses	horse	NNS
cord-022561-rv5j1201	1620	5	the	the	DT
cord-022561-rv5j1201	1620	6	three	three	CD
cord-022561-rv5j1201	1620	7	muscular	muscular	JJ
cord-022561-rv5j1201	1620	8	layers	layer	NNS
cord-022561-rv5j1201	1620	9	of	of	IN
cord-022561-rv5j1201	1620	10	the	the	DT
cord-022561-rv5j1201	1620	11	capsule	capsule	NN
cord-022561-rv5j1201	1620	12	lie	lie	VBP
cord-022561-rv5j1201	1620	13	perpendicular	perpendicular	JJ
cord-022561-rv5j1201	1620	14	to	to	IN
cord-022561-rv5j1201	1620	15	each	each	DT
cord-022561-rv5j1201	1620	16	other	other	JJ
cord-022561-rv5j1201	1620	17	,	,	,
cord-022561-rv5j1201	1620	18	forming	form	VBG
cord-022561-rv5j1201	1620	19	a	a	DT
cord-022561-rv5j1201	1620	20	capsule	capsule	NN
cord-022561-rv5j1201	1620	21	thicker	thick	JJR
cord-022561-rv5j1201	1620	22	than	than	IN
cord-022561-rv5j1201	1620	23	that	that	DT
cord-022561-rv5j1201	1620	24	of	of	IN
cord-022561-rv5j1201	1620	25	carnivores	carnivore	NNS
cord-022561-rv5j1201	1620	26	.	.	.
cord-022561-rv5j1201	1621	1	Carnivores	carnivore	NNS
cord-022561-rv5j1201	1621	2	,	,	,
cord-022561-rv5j1201	1621	3	small	small	JJ
cord-022561-rv5j1201	1621	4	ruminants	ruminant	NNS
cord-022561-rv5j1201	1621	5	,	,	,
cord-022561-rv5j1201	1621	6	and	and	CC
cord-022561-rv5j1201	1621	7	pigs	pig	NNS
cord-022561-rv5j1201	1621	8	have	have	VBP
cord-022561-rv5j1201	1621	9	interwoven	interweave	VBN
cord-022561-rv5j1201	1621	10	smooth	smooth	JJ
cord-022561-rv5j1201	1621	11	muscle	muscle	NN
cord-022561-rv5j1201	1621	12	within	within	IN
cord-022561-rv5j1201	1621	13	the	the	DT
cord-022561-rv5j1201	1621	14	splenic	splenic	JJ
cord-022561-rv5j1201	1621	15	capsule	capsule	NN
cord-022561-rv5j1201	1621	16	,	,	,
cord-022561-rv5j1201	1621	17	and	and	CC
cord-022561-rv5j1201	1621	18	pigs	pig	NNS
cord-022561-rv5j1201	1621	19	also	also	RB
cord-022561-rv5j1201	1621	20	have	have	VBP
cord-022561-rv5j1201	1621	21	abundant	abundant	JJ
cord-022561-rv5j1201	1621	22	elastic	elastic	JJ
cord-022561-rv5j1201	1621	23	fibers	fiber	NNS
cord-022561-rv5j1201	1621	24	within	within	IN
cord-022561-rv5j1201	1621	25	the	the	DT
cord-022561-rv5j1201	1621	26	capsule	capsule	NN
cord-022561-rv5j1201	1621	27	.	.	.
cord-022561-rv5j1201	1622	1	The	the	DT
cord-022561-rv5j1201	1622	2	spleen	spleen	NN
cord-022561-rv5j1201	1622	3	differs	differ	VBZ
cord-022561-rv5j1201	1622	4	from	from	IN
cord-022561-rv5j1201	1622	5	many	many	JJ
cord-022561-rv5j1201	1622	6	other	other	JJ
cord-022561-rv5j1201	1622	7	organs	organ	NNS
cord-022561-rv5j1201	1622	8	in	in	IN
cord-022561-rv5j1201	1622	9	the	the	DT
cord-022561-rv5j1201	1622	10	organization	organization	NN
cord-022561-rv5j1201	1622	11	of	of	IN
cord-022561-rv5j1201	1622	12	its	-PRON-	PRP$
cord-022561-rv5j1201	1622	13	parenchyma	parenchyma	NN
cord-022561-rv5j1201	1622	14	.	.	.
cord-022561-rv5j1201	1623	1	Instead	instead	RB
cord-022561-rv5j1201	1623	2	of	of	IN
cord-022561-rv5j1201	1623	3	a	a	DT
cord-022561-rv5j1201	1623	4	cortex	cortex	NN
cord-022561-rv5j1201	1623	5	and	and	CC
cord-022561-rv5j1201	1623	6	medulla	medulla	NN
cord-022561-rv5j1201	1623	7	,	,	,
cord-022561-rv5j1201	1623	8	the	the	DT
cord-022561-rv5j1201	1623	9	spleen	spleen	NN
cord-022561-rv5j1201	1623	10	is	be	VBZ
cord-022561-rv5j1201	1623	11	divided	divide	VBN
cord-022561-rv5j1201	1623	12	into	into	IN
cord-022561-rv5j1201	1623	13	two	two	CD
cord-022561-rv5j1201	1623	14	distinct	distinct	JJ
cord-022561-rv5j1201	1623	15	structural	structural	JJ
cord-022561-rv5j1201	1623	16	and	and	CC
cord-022561-rv5j1201	1623	17	functional	functional	JJ
cord-022561-rv5j1201	1623	18	components	component	NNS
cord-022561-rv5j1201	1623	19	:	:	:
cord-022561-rv5j1201	1623	20	the	the	DT
cord-022561-rv5j1201	1623	21	red	red	JJ
cord-022561-rv5j1201	1623	22	pulp	pulp	NN
cord-022561-rv5j1201	1623	23	and	and	CC
cord-022561-rv5j1201	1623	24	white	white	JJ
cord-022561-rv5j1201	1623	25	pulp	pulp	NN
cord-022561-rv5j1201	1623	26	(	(	-LRB-
cord-022561-rv5j1201	1623	27	Fig	Fig	NNP
cord-022561-rv5j1201	1623	28	.	.	.
cord-022561-rv5j1201	1623	29	13	13	CD
cord-022561-rv5j1201	1623	30	-	-	SYM
cord-022561-rv5j1201	1623	31	38	38	CD
cord-022561-rv5j1201	1623	32	)	)	-RRB-
cord-022561-rv5j1201	1623	33	.	.	.
cord-022561-rv5j1201	1624	1	With	with	IN
cord-022561-rv5j1201	1624	2	hematoxylin	hematoxylin	NNP
cord-022561-rv5j1201	1624	3	and	and	CC
cord-022561-rv5j1201	1624	4	eosin	eosin	NNP
cord-022561-rv5j1201	1624	5	(	(	-LRB-
cord-022561-rv5j1201	1624	6	H&E	H&E	NNP
cord-022561-rv5j1201	1624	7	)	)	-RRB-
cord-022561-rv5j1201	1624	8	staining	staining	NN
cord-022561-rv5j1201	1624	9	,	,	,
cord-022561-rv5j1201	1624	10	red	red	JJ
cord-022561-rv5j1201	1624	11	pulp	pulp	NN
cord-022561-rv5j1201	1624	12	appears	appear	VBZ
cord-022561-rv5j1201	1624	13	red	red	JJ
cord-022561-rv5j1201	1624	14	-	-	HYPH
cord-022561-rv5j1201	1624	15	pink	pink	JJ
cord-022561-rv5j1201	1624	16	because	because	IN
cord-022561-rv5j1201	1624	17	of	of	IN
cord-022561-rv5j1201	1624	18	the	the	DT
cord-022561-rv5j1201	1624	19	abundance	abundance	NN
cord-022561-rv5j1201	1624	20	of	of	IN
cord-022561-rv5j1201	1624	21	red	red	JJ
cord-022561-rv5j1201	1624	22	blood	blood	NN
cord-022561-rv5j1201	1624	23	cells	cell	NNS
cord-022561-rv5j1201	1624	24	,	,	,
cord-022561-rv5j1201	1624	25	whereas	whereas	IN
cord-022561-rv5j1201	1624	26	white	white	JJ
cord-022561-rv5j1201	1624	27	pulp	pulp	NN
cord-022561-rv5j1201	1624	28	appears	appear	VBZ
cord-022561-rv5j1201	1624	29	blue	blue	JJ
cord-022561-rv5j1201	1624	30	-	-	HYPH
cord-022561-rv5j1201	1624	31	purple	purple	NN
cord-022561-rv5j1201	1624	32	because	because	IN
cord-022561-rv5j1201	1624	33	of	of	IN
cord-022561-rv5j1201	1624	34	the	the	DT
cord-022561-rv5j1201	1624	35	heavy	heavy	JJ
cord-022561-rv5j1201	1624	36	concentration	concentration	NN
cord-022561-rv5j1201	1624	37	of	of	IN
cord-022561-rv5j1201	1624	38	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	1624	39	.	.	.
cord-022561-rv5j1201	1625	1	The	the	DT
cord-022561-rv5j1201	1625	2	white	white	JJ
cord-022561-rv5j1201	1625	3	pulp	pulp	NN
cord-022561-rv5j1201	1625	4	consists	consist	NNS
cord-022561-rv5j1201	1625	5	of	of	IN
cord-022561-rv5j1201	1625	6	splenic	splenic	JJ
cord-022561-rv5j1201	1625	7	follicles	follicle	NNS
cord-022561-rv5j1201	1625	8	,	,	,
cord-022561-rv5j1201	1625	9	populated	populate	VBN
cord-022561-rv5j1201	1625	10	by	by	IN
cord-022561-rv5j1201	1625	11	B	b	NN
cord-022561-rv5j1201	1625	12	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	1625	13	;	;	:
cord-022561-rv5j1201	1625	14	the	the	DT
cord-022561-rv5j1201	1625	15	PALS	pals	NN
cord-022561-rv5j1201	1625	16	,	,	,
cord-022561-rv5j1201	1625	17	inhabited	inhabit	VBN
cord-022561-rv5j1201	1625	18	by	by	IN
cord-022561-rv5j1201	1625	19	T	T	NNP
cord-022561-rv5j1201	1625	20	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	1625	21	;	;	:
cord-022561-rv5j1201	1625	22	and	and	CC
cord-022561-rv5j1201	1625	23	the	the	DT
cord-022561-rv5j1201	1625	24	marginal	marginal	JJ
cord-022561-rv5j1201	1625	25	zone	zone	NN
cord-022561-rv5j1201	1625	26	at	at	IN
cord-022561-rv5j1201	1625	27	the	the	DT
cord-022561-rv5j1201	1625	28	periphery	periphery	NN
cord-022561-rv5j1201	1625	29	of	of	IN
cord-022561-rv5j1201	1625	30	follicles	follicle	NNS
cord-022561-rv5j1201	1625	31	.	.	.
cord-022561-rv5j1201	1626	1	Macrophages	macrophage	NNS
cord-022561-rv5j1201	1626	2	,	,	,
cord-022561-rv5j1201	1626	3	antigen	antigen	NN
cord-022561-rv5j1201	1626	4	-	-	HYPH
cord-022561-rv5j1201	1626	5	presenting	present	VBG
cord-022561-rv5j1201	1626	6	cells	cell	NNS
cord-022561-rv5j1201	1626	7	,	,	,
cord-022561-rv5j1201	1626	8	and	and	CC
cord-022561-rv5j1201	1626	9	trafficking	traffic	VBG
cord-022561-rv5j1201	1626	10	B	b	NN
cord-022561-rv5j1201	1626	11	and	and	CC
cord-022561-rv5j1201	1626	12	T	t	NN
cord-022561-rv5j1201	1626	13	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	1626	14	populate	populate	VBP
cord-022561-rv5j1201	1626	15	the	the	DT
cord-022561-rv5j1201	1626	16	marginal	marginal	JJ
cord-022561-rv5j1201	1626	17	zone	zone	NN
cord-022561-rv5j1201	1626	18	.	.	.
cord-022561-rv5j1201	1627	1	The	the	DT
cord-022561-rv5j1201	1627	2	radial	radial	JJ
cord-022561-rv5j1201	1627	3	arteries	artery	NNS
cord-022561-rv5j1201	1627	4	,	,	,
cord-022561-rv5j1201	1627	5	branches	branch	NNS
cord-022561-rv5j1201	1627	6	of	of	IN
cord-022561-rv5j1201	1627	7	the	the	DT
cord-022561-rv5j1201	1627	8	central	central	JJ
cord-022561-rv5j1201	1627	9	artery	artery	NN
cord-022561-rv5j1201	1627	10	(	(	-LRB-
cord-022561-rv5j1201	1627	11	also	also	RB
cord-022561-rv5j1201	1627	12	known	know	VBN
cord-022561-rv5j1201	1627	13	as	as	IN
cord-022561-rv5j1201	1627	14	central	central	JJ
cord-022561-rv5j1201	1627	15	arteriole	arteriole	NNP
cord-022561-rv5j1201	1627	16	)	)	-RRB-
cord-022561-rv5j1201	1627	17	,	,	,
cord-022561-rv5j1201	1627	18	and	and	CC
cord-022561-rv5j1201	1627	19	capillaries	capillary	NNS
cord-022561-rv5j1201	1627	20	from	from	IN
cord-022561-rv5j1201	1627	21	both	both	DT
cord-022561-rv5j1201	1627	22	red	red	JJ
cord-022561-rv5j1201	1627	23	and	and	CC
cord-022561-rv5j1201	1627	24	white	white	JJ
cord-022561-rv5j1201	1627	25	pulp	pulp	NN
cord-022561-rv5j1201	1627	26	drain	drain	NN
cord-022561-rv5j1201	1627	27	into	into	IN
cord-022561-rv5j1201	1627	28	the	the	DT
cord-022561-rv5j1201	1627	29	marginal	marginal	JJ
cord-022561-rv5j1201	1627	30	sinus	sinus	NN
cord-022561-rv5j1201	1627	31	of	of	IN
cord-022561-rv5j1201	1627	32	the	the	DT
cord-022561-rv5j1201	1627	33	marginal	marginal	JJ
cord-022561-rv5j1201	1627	34	zone	zone	NN
cord-022561-rv5j1201	1627	35	,	,	,
cord-022561-rv5j1201	1627	36	although	although	IN
cord-022561-rv5j1201	1627	37	the	the	DT
cord-022561-rv5j1201	1627	38	latter	latter	NN
cord-022561-rv5j1201	1627	39	has	have	VBZ
cord-022561-rv5j1201	1627	40	not	not	RB
cord-022561-rv5j1201	1627	41	been	be	VBN
cord-022561-rv5j1201	1627	42	shown	show	VBN
cord-022561-rv5j1201	1627	43	to	to	TO
cord-022561-rv5j1201	1627	44	be	be	VB
cord-022561-rv5j1201	1627	45	the	the	DT
cord-022561-rv5j1201	1627	46	case	case	NN
cord-022561-rv5j1201	1627	47	in	in	IN
cord-022561-rv5j1201	1627	48	all	all	DT
cord-022561-rv5j1201	1627	49	species	specie	NNS
cord-022561-rv5j1201	1627	50	to	to	IN
cord-022561-rv5j1201	1627	51	the	the	DT
cord-022561-rv5j1201	1627	52	same	same	JJ
cord-022561-rv5j1201	1627	53	degree	degree	NN
cord-022561-rv5j1201	1627	54	(	(	-LRB-
cord-022561-rv5j1201	1627	55	e.g.	e.g.	RB
cord-022561-rv5j1201	1627	56	,	,	,
cord-022561-rv5j1201	1627	57	the	the	DT
cord-022561-rv5j1201	1627	58	cat	cat	NN
cord-022561-rv5j1201	1627	59	has	have	VBZ
cord-022561-rv5j1201	1627	60	a	a	DT
cord-022561-rv5j1201	1627	61	small	small	JJ
cord-022561-rv5j1201	1627	62	marginal	marginal	JJ
cord-022561-rv5j1201	1627	63	sinus	sinus	NN
cord-022561-rv5j1201	1627	64	but	but	CC
cord-022561-rv5j1201	1627	65	a	a	DT
cord-022561-rv5j1201	1627	66	well	well	RB
cord-022561-rv5j1201	1627	67	-	-	HYPH
cord-022561-rv5j1201	1627	68	developed	develop	VBN
cord-022561-rv5j1201	1627	69	PAMS	PAMS	NNP
cord-022561-rv5j1201	1627	70	)	)	-RRB-
cord-022561-rv5j1201	1628	1	(	(	-LRB-
cord-022561-rv5j1201	1628	2	Figs	fig	NNS
cord-022561-rv5j1201	1628	3	.	.	.
cord-022561-rv5j1201	1629	1	13	13	CD
cord-022561-rv5j1201	1629	2	-	-	SYM
cord-022561-rv5j1201	1629	3	39	39	CD
cord-022561-rv5j1201	1629	4	and	and	CC
cord-022561-rv5j1201	1629	5	13	13	CD
cord-022561-rv5j1201	1629	6	-	-	SYM
cord-022561-rv5j1201	1629	7	40	40	CD
cord-022561-rv5j1201	1629	8	)	)	-RRB-
cord-022561-rv5j1201	1629	9	.	.	.
cord-022561-rv5j1201	1630	1	The	the	DT
cord-022561-rv5j1201	1630	2	red	red	JJ
cord-022561-rv5j1201	1630	3	pulp	pulp	NN
cord-022561-rv5j1201	1630	4	consists	consist	NNS
cord-022561-rv5j1201	1630	5	of	of	IN
cord-022561-rv5j1201	1630	6	cells	cell	NNS
cord-022561-rv5j1201	1630	7	of	of	IN
cord-022561-rv5j1201	1630	8	the	the	DT
cord-022561-rv5j1201	1630	9	monocyte	monocyte	JJ
cord-022561-rv5j1201	1630	10	-	-	HYPH
cord-022561-rv5j1201	1630	11	macrophage	macrophage	NN
cord-022561-rv5j1201	1630	12	system	system	NN
cord-022561-rv5j1201	1630	13	,	,	,
cord-022561-rv5j1201	1630	14	PAMS	PAMS	NNP
cord-022561-rv5j1201	1630	15	,	,	,
cord-022561-rv5j1201	1630	16	sinusoids	sinusoid	NNS
cord-022561-rv5j1201	1630	17	(	(	-LRB-
cord-022561-rv5j1201	1630	18	dogs	dog	NNS
cord-022561-rv5j1201	1630	19	,	,	,
cord-022561-rv5j1201	1630	20	rats	rat	NNS
cord-022561-rv5j1201	1630	21	,	,	,
cord-022561-rv5j1201	1630	22	and	and	CC
cord-022561-rv5j1201	1630	23	human	human	JJ
cord-022561-rv5j1201	1630	24	beings	being	NNS
cord-022561-rv5j1201	1630	25	only	only	RB
cord-022561-rv5j1201	1630	26	)	)	-RRB-
cord-022561-rv5j1201	1630	27	,	,	,
cord-022561-rv5j1201	1630	28	red	red	JJ
cord-022561-rv5j1201	1630	29	pulp	pulp	NN
cord-022561-rv5j1201	1630	30	vascular	vascular	JJ
cord-022561-rv5j1201	1630	31	spaces	space	NNS
cord-022561-rv5j1201	1630	32	,	,	,
cord-022561-rv5j1201	1630	33	and	and	CC
cord-022561-rv5j1201	1630	34	associated	associated	JJ
cord-022561-rv5j1201	1630	35	stromal	stromal	JJ
cord-022561-rv5j1201	1630	36	elements	element	NNS
cord-022561-rv5j1201	1630	37	such	such	JJ
cord-022561-rv5j1201	1630	38	as	as	IN
cord-022561-rv5j1201	1630	39	reticular	reticular	JJ
cord-022561-rv5j1201	1630	40	cells	cell	NNS
cord-022561-rv5j1201	1630	41	,	,	,
cord-022561-rv5j1201	1630	42	fibroblasts	fibroblast	NNS
cord-022561-rv5j1201	1630	43	,	,	,
cord-022561-rv5j1201	1630	44	and	and	CC
cord-022561-rv5j1201	1630	45	trabecular	trabecular	NN
cord-022561-rv5j1201	1630	46	myocytes	myocyte	NNS
cord-022561-rv5j1201	1630	47	.	.	.
cord-022561-rv5j1201	1631	1	The	the	DT
cord-022561-rv5j1201	1631	2	labyrinth	labyrinth	NN
cord-022561-rv5j1201	1631	3	of	of	IN
cord-022561-rv5j1201	1631	4	the	the	DT
cord-022561-rv5j1201	1631	5	splenic	splenic	JJ
cord-022561-rv5j1201	1631	6	red	red	JJ
cord-022561-rv5j1201	1631	7	pulp	pulp	NN
cord-022561-rv5j1201	1631	8	vascular	vascular	JJ
cord-022561-rv5j1201	1631	9	spaces	space	NNS
cord-022561-rv5j1201	1631	10	serves	serve	VBZ
cord-022561-rv5j1201	1631	11	as	as	IN
cord-022561-rv5j1201	1631	12	both	both	CC
cord-022561-rv5j1201	1631	13	a	a	DT
cord-022561-rv5j1201	1631	14	functional	functional	JJ
cord-022561-rv5j1201	1631	15	and	and	CC
cord-022561-rv5j1201	1631	16	physical	physical	JJ
cord-022561-rv5j1201	1631	17	filter	filter	NN
cord-022561-rv5j1201	1631	18	for	for	IN
cord-022561-rv5j1201	1631	19	circulating	circulate	VBG
cord-022561-rv5j1201	1631	20	blood	blood	NN
cord-022561-rv5j1201	1631	21	cells	cell	NNS
cord-022561-rv5j1201	1631	22	.	.	.
cord-022561-rv5j1201	1632	1	The	the	DT
cord-022561-rv5j1201	1632	2	blood	blood	NN
cord-022561-rv5j1201	1632	3	circulation	circulation	NN
cord-022561-rv5j1201	1632	4	of	of	IN
cord-022561-rv5j1201	1632	5	the	the	DT
cord-022561-rv5j1201	1632	6	spleen	spleen	NN
cord-022561-rv5j1201	1632	7	is	be	VBZ
cord-022561-rv5j1201	1632	8	particularly	particularly	RB
cord-022561-rv5j1201	1632	9	suited	suited	JJ
cord-022561-rv5j1201	1632	10	to	to	TO
cord-022561-rv5j1201	1632	11	enable	enable	VB
cord-022561-rv5j1201	1632	12	its	-PRON-	PRP$
cord-022561-rv5j1201	1632	13	functions	function	NNS
cord-022561-rv5j1201	1632	14	,	,	,
cord-022561-rv5j1201	1632	15	namely	namely	RB
cord-022561-rv5j1201	1632	16	,	,	,
cord-022561-rv5j1201	1632	17	(	(	-LRB-
cord-022561-rv5j1201	1632	18	1	1	LS
cord-022561-rv5j1201	1632	19	)	)	-RRB-
cord-022561-rv5j1201	1632	20	filtering	filter	VBG
cord-022561-rv5j1201	1632	21	and	and	CC
cord-022561-rv5j1201	1632	22	clearing	clear	VBG
cord-022561-rv5j1201	1632	23	the	the	DT
cord-022561-rv5j1201	1632	24	blood	blood	NN
cord-022561-rv5j1201	1632	25	of	of	IN
cord-022561-rv5j1201	1632	26	atrophy	atrophy	NN
cord-022561-rv5j1201	1632	27	must	must	MD
cord-022561-rv5j1201	1632	28	be	be	VB
cord-022561-rv5j1201	1632	29	differentiated	differentiate	VBN
cord-022561-rv5j1201	1632	30	from	from	IN
cord-022561-rv5j1201	1632	31	involution	involution	NN
cord-022561-rv5j1201	1632	32	,	,	,
cord-022561-rv5j1201	1632	33	which	which	WDT
cord-022561-rv5j1201	1632	34	normally	normally	RB
cord-022561-rv5j1201	1632	35	begins	begin	VBZ
cord-022561-rv5j1201	1632	36	at	at	IN
cord-022561-rv5j1201	1632	37	sexual	sexual	JJ
cord-022561-rv5j1201	1632	38	maturity	maturity	NN
cord-022561-rv5j1201	1632	39	.	.	.
cord-022561-rv5j1201	1633	1	This	this	DT
cord-022561-rv5j1201	1633	2	distinction	distinction	NN
cord-022561-rv5j1201	1633	3	is	be	VBZ
cord-022561-rv5j1201	1633	4	difficult	difficult	JJ
cord-022561-rv5j1201	1633	5	to	to	TO
cord-022561-rv5j1201	1633	6	make	make	VB
cord-022561-rv5j1201	1633	7	,	,	,
cord-022561-rv5j1201	1633	8	unless	unless	IN
cord-022561-rv5j1201	1633	9	the	the	DT
cord-022561-rv5j1201	1633	10	change	change	NN
cord-022561-rv5j1201	1633	11	is	be	VBZ
cord-022561-rv5j1201	1633	12	extreme	extreme	JJ
cord-022561-rv5j1201	1633	13	or	or	CC
cord-022561-rv5j1201	1633	14	age	age	NN
cord-022561-rv5j1201	1633	15	-	-	HYPH
cord-022561-rv5j1201	1633	16	matched	match	VBN
cord-022561-rv5j1201	1633	17	control	control	NN
cord-022561-rv5j1201	1633	18	animals	animal	NNS
cord-022561-rv5j1201	1633	19	are	be	VBP
cord-022561-rv5j1201	1633	20	available	available	JJ
cord-022561-rv5j1201	1633	21	for	for	IN
cord-022561-rv5j1201	1633	22	comparison	comparison	NN
cord-022561-rv5j1201	1633	23	.	.	.
cord-022561-rv5j1201	1634	1	Inflammation	inflammation	NN
cord-022561-rv5j1201	1634	2	.	.	.
cord-022561-rv5j1201	1635	1	Inflammation	inflammation	NN
cord-022561-rv5j1201	1635	2	of	of	IN
cord-022561-rv5j1201	1635	3	the	the	DT
cord-022561-rv5j1201	1635	4	thymus	thymus	NN
cord-022561-rv5j1201	1635	5	is	be	VBZ
cord-022561-rv5j1201	1635	6	rare	rare	JJ
cord-022561-rv5j1201	1635	7	.	.	.
cord-022561-rv5j1201	1636	1	Neutrophils	neutrophils	NN
cord-022561-rv5j1201	1636	2	and	and	CC
cord-022561-rv5j1201	1636	3	macrophages	macrophage	NNS
cord-022561-rv5j1201	1636	4	are	be	VBP
cord-022561-rv5j1201	1636	5	often	often	RB
cord-022561-rv5j1201	1636	6	present	present	JJ
cord-022561-rv5j1201	1636	7	within	within	IN
cord-022561-rv5j1201	1636	8	keratinized	keratinized	JJ
cord-022561-rv5j1201	1636	9	Hassall	Hassall	NNP
cord-022561-rv5j1201	1636	10	's	's	POS
cord-022561-rv5j1201	1636	11	corpuscles	corpuscle	NNS
cord-022561-rv5j1201	1636	12	during	during	IN
cord-022561-rv5j1201	1636	13	involution	involution	NN
cord-022561-rv5j1201	1636	14	and	and	CC
cord-022561-rv5j1201	1636	15	should	should	MD
cord-022561-rv5j1201	1636	16	not	not	RB
cord-022561-rv5j1201	1636	17	be	be	VB
cord-022561-rv5j1201	1636	18	mistaken	mistake	VBN
cord-022561-rv5j1201	1636	19	for	for	IN
cord-022561-rv5j1201	1636	20	a	a	DT
cord-022561-rv5j1201	1636	21	true	true	JJ
cord-022561-rv5j1201	1636	22	thymitis	thymitis	NNP
cord-022561-rv5j1201	1636	23	.	.	.
cord-022561-rv5j1201	1637	1	Thymitis	Thymitis	NNP
cord-022561-rv5j1201	1637	2	has	have	VBZ
cord-022561-rv5j1201	1637	3	been	be	VBN
cord-022561-rv5j1201	1637	4	reported	report	VBN
cord-022561-rv5j1201	1637	5	in	in	IN
cord-022561-rv5j1201	1637	6	salmon	salmon	NN
cord-022561-rv5j1201	1637	7	poisoning	poisoning	NN
cord-022561-rv5j1201	1637	8	disease	disease	NN
cord-022561-rv5j1201	1637	9	of	of	IN
cord-022561-rv5j1201	1637	10	dogs	dog	NNS
cord-022561-rv5j1201	1637	11	(	(	-LRB-
cord-022561-rv5j1201	1637	12	see	see	VB
cord-022561-rv5j1201	1637	13	Chapter	Chapter	NNP
cord-022561-rv5j1201	1637	14	7	7	CD
cord-022561-rv5j1201	1637	15	)	)	-RRB-
cord-022561-rv5j1201	1637	16	,	,	,
cord-022561-rv5j1201	1637	17	epizootic	epizootic	JJ
cord-022561-rv5j1201	1637	18	bovine	bovine	JJ
cord-022561-rv5j1201	1637	19	abortion	abortion	NN
cord-022561-rv5j1201	1637	20	(	(	-LRB-
cord-022561-rv5j1201	1637	21	see	see	VB
cord-022561-rv5j1201	1637	22	Chapter	chapter	NN
cord-022561-rv5j1201	1637	23	18	18	CD
cord-022561-rv5j1201	1637	24	)	)	-RRB-
cord-022561-rv5j1201	1637	25	,	,	,
cord-022561-rv5j1201	1637	26	and	and	CC
cord-022561-rv5j1201	1637	27	in	in	IN
cord-022561-rv5j1201	1637	28	pigs	pig	NNS
cord-022561-rv5j1201	1637	29	infected	infect	VBN
cord-022561-rv5j1201	1637	30	with	with	IN
cord-022561-rv5j1201	1637	31	porcine	porcine	JJ
cord-022561-rv5j1201	1637	32	circovirus	circovirus	JJ
cord-022561-rv5j1201	1637	33	type	type	NN
cord-022561-rv5j1201	1637	34	2	2	CD
cord-022561-rv5j1201	1638	1	(	(	-LRB-
cord-022561-rv5j1201	1638	2	PCV2	PCV2	NNP
cord-022561-rv5j1201	1638	3	)	)	-RRB-
cord-022561-rv5j1201	1638	4	.	.	.
cord-022561-rv5j1201	1639	1	Necrosis	necrosis	NN
cord-022561-rv5j1201	1639	2	and	and	CC
cord-022561-rv5j1201	1639	3	secondary	secondary	JJ
cord-022561-rv5j1201	1639	4	infiltrates	infiltrate	NNS
cord-022561-rv5j1201	1639	5	of	of	IN
cord-022561-rv5j1201	1639	6	neutrophils	neutrophil	NNS
cord-022561-rv5j1201	1639	7	and	and	CC
cord-022561-rv5j1201	1639	8	macrophages	macrophage	NNS
cord-022561-rv5j1201	1639	9	may	may	MD
cord-022561-rv5j1201	1639	10	be	be	VB
cord-022561-rv5j1201	1639	11	seen	see	VBN
cord-022561-rv5j1201	1639	12	in	in	IN
cord-022561-rv5j1201	1639	13	other	other	JJ
cord-022561-rv5j1201	1639	14	infectious	infectious	JJ
cord-022561-rv5j1201	1639	15	diseases	disease	NNS
cord-022561-rv5j1201	1639	16	(	(	-LRB-
cord-022561-rv5j1201	1639	17	e.g.	e.g.	RB
cord-022561-rv5j1201	1639	18	,	,	,
cord-022561-rv5j1201	1639	19	equine	equine	JJ
cord-022561-rv5j1201	1639	20	herpesvirus	herpesvirus	NN
cord-022561-rv5j1201	1639	21	1	1	CD
cord-022561-rv5j1201	1639	22	[	[	-LRB-
cord-022561-rv5j1201	1639	23	EHV-1	EHV-1	NNP
cord-022561-rv5j1201	1639	24	]	]	-RRB-
cord-022561-rv5j1201	1639	25	)	)	-RRB-
cord-022561-rv5j1201	1639	26	.	.	.
cord-022561-rv5j1201	1639	27	 	 	_SP
cord-022561-rv5j1201	1640	1	The	the	DT
cord-022561-rv5j1201	1640	2	main	main	JJ
cord-022561-rv5j1201	1640	3	portal	portal	NN
cord-022561-rv5j1201	1640	4	of	of	IN
cord-022561-rv5j1201	1640	5	entry	entry	NN
cord-022561-rv5j1201	1640	6	to	to	IN
cord-022561-rv5j1201	1640	7	the	the	DT
cord-022561-rv5j1201	1640	8	thymus	thymus	NN
cord-022561-rv5j1201	1640	9	is	be	VBZ
cord-022561-rv5j1201	1640	10	hematogenous	hematogenous	JJ
cord-022561-rv5j1201	1640	11	.	.	.
cord-022561-rv5j1201	1641	1	Portals	portal	NNS
cord-022561-rv5j1201	1641	2	of	of	IN
cord-022561-rv5j1201	1641	3	entry	entry	NN
cord-022561-rv5j1201	1641	4	used	use	VBN
cord-022561-rv5j1201	1641	5	by	by	IN
cord-022561-rv5j1201	1641	6	microorganisms	microorganism	NNS
cord-022561-rv5j1201	1641	7	and	and	CC
cord-022561-rv5j1201	1641	8	other	other	JJ
cord-022561-rv5j1201	1641	9	agents	agent	NNS
cord-022561-rv5j1201	1641	10	and	and	CC
cord-022561-rv5j1201	1641	11	substances	substance	NNS
cord-022561-rv5j1201	1641	12	to	to	TO
cord-022561-rv5j1201	1641	13	access	access	VB
cord-022561-rv5j1201	1641	14	the	the	DT
cord-022561-rv5j1201	1641	15	lymphatic	lymphatic	JJ
cord-022561-rv5j1201	1641	16	system	system	NN
cord-022561-rv5j1201	1641	17	are	be	VBP
cord-022561-rv5j1201	1641	18	summarized	summarize	VBN
cord-022561-rv5j1201	1641	19	in	in	IN
cord-022561-rv5j1201	1641	20	Box	Box	NNP
cord-022561-rv5j1201	1641	21	13	13	CD
cord-022561-rv5j1201	1641	22	-	-	SYM
cord-022561-rv5j1201	1641	23	6	6	CD
cord-022561-rv5j1201	1641	24	.	.	.
cord-022561-rv5j1201	1642	1	These	these	DT
cord-022561-rv5j1201	1642	2	portals	portal	NNS
cord-022561-rv5j1201	1642	3	include	include	VBP
cord-022561-rv5j1201	1642	4	the	the	DT
cord-022561-rv5j1201	1642	5	blood	blood	NN
cord-022561-rv5j1201	1642	6	vessels	vessel	NNS
cord-022561-rv5j1201	1642	7	(	(	-LRB-
cord-022561-rv5j1201	1642	8	hematogenous	hematogenous	NNP
cord-022561-rv5j1201	1642	9	spread	spread	VBN
cord-022561-rv5j1201	1642	10	by	by	IN
cord-022561-rv5j1201	1642	11	microorganisms	microorganism	NNS
cord-022561-rv5j1201	1642	12	free	free	JJ
cord-022561-rv5j1201	1642	13	in	in	IN
cord-022561-rv5j1201	1642	14	the	the	DT
cord-022561-rv5j1201	1642	15	plasma	plasma	NN
cord-022561-rv5j1201	1642	16	or	or	CC
cord-022561-rv5j1201	1642	17	within	within	IN
cord-022561-rv5j1201	1642	18	circulating	circulate	VBG
cord-022561-rv5j1201	1642	19	leukocytes	leukocyte	NNS
cord-022561-rv5j1201	1642	20	or	or	CC
cord-022561-rv5j1201	1642	21	erythrocytes	erythrocyte	NNS
cord-022561-rv5j1201	1642	22	)	)	-RRB-
cord-022561-rv5j1201	1642	23	,	,	,
cord-022561-rv5j1201	1642	24	afferent	afferent	JJ
cord-022561-rv5j1201	1642	25	lymphatic	lymphatic	NN
cord-022561-rv5j1201	1642	26	vessels	vessel	NNS
cord-022561-rv5j1201	1642	27	(	(	-LRB-
cord-022561-rv5j1201	1642	28	lymphatic	lymphatic	JJ
cord-022561-rv5j1201	1642	29	spread	spread	NN
cord-022561-rv5j1201	1642	30	)	)	-RRB-
cord-022561-rv5j1201	1642	31	,	,	,
cord-022561-rv5j1201	1642	32	direct	direct	JJ
cord-022561-rv5j1201	1642	33	penetration	penetration	NN
cord-022561-rv5j1201	1642	34	,	,	,
cord-022561-rv5j1201	1642	35	or	or	CC
cord-022561-rv5j1201	1642	36	through	through	IN
cord-022561-rv5j1201	1642	37	M	M	NNP
cord-022561-rv5j1201	1642	38	(	(	-LRB-
cord-022561-rv5j1201	1642	39	for	for	IN
cord-022561-rv5j1201	1642	40	"	"	``
cord-022561-rv5j1201	1642	41	microfold	microfold	JJ
cord-022561-rv5j1201	1642	42	"	"	''
cord-022561-rv5j1201	1642	43	)	)	-RRB-
cord-022561-rv5j1201	1642	44	cells	cell	NNS
cord-022561-rv5j1201	1642	45	and	and	CC
cord-022561-rv5j1201	1642	46	DCs	dc	NNS
cord-022561-rv5j1201	1642	47	in	in	IN
cord-022561-rv5j1201	1642	48	MALT	MALT	NNP
cord-022561-rv5j1201	1642	49	.	.	.
cord-022561-rv5j1201	1643	1	Defense	defense	NN
cord-022561-rv5j1201	1643	2	mechanisms	mechanism	NNS
cord-022561-rv5j1201	1643	3	used	use	VBN
cord-022561-rv5j1201	1643	4	by	by	IN
cord-022561-rv5j1201	1643	5	the	the	DT
cord-022561-rv5j1201	1643	6	thymus	thymus	NN
cord-022561-rv5j1201	1643	7	to	to	TO
cord-022561-rv5j1201	1643	8	protect	protect	VB
cord-022561-rv5j1201	1643	9	itself	-PRON-	PRP
cord-022561-rv5j1201	1643	10	against	against	IN
cord-022561-rv5j1201	1643	11	microorganisms	microorganism	NNS
cord-022561-rv5j1201	1643	12	and	and	CC
cord-022561-rv5j1201	1643	13	other	other	JJ
cord-022561-rv5j1201	1643	14	agents	agent	NNS
cord-022561-rv5j1201	1643	15	are	be	VBP
cord-022561-rv5j1201	1643	16	the	the	DT
cord-022561-rv5j1201	1643	17	innate	innate	JJ
cord-022561-rv5j1201	1643	18	and	and	CC
cord-022561-rv5j1201	1643	19	adaptive	adaptive	JJ
cord-022561-rv5j1201	1643	20	immune	immune	JJ
cord-022561-rv5j1201	1643	21	responses	response	NNS
cord-022561-rv5j1201	1643	22	,	,	,
cord-022561-rv5j1201	1643	23	discussed	discuss	VBN
cord-022561-rv5j1201	1643	24	in	in	IN
cord-022561-rv5j1201	1643	25	Chapters	chapter	NNS
cord-022561-rv5j1201	1643	26	3	3	CD
cord-022561-rv5j1201	1643	27	,	,	,
cord-022561-rv5j1201	1643	28	4	4	CD
cord-022561-rv5j1201	1643	29	,	,	,
cord-022561-rv5j1201	1643	30	and	and	CC
cord-022561-rv5j1201	1643	31	5	5	CD
cord-022561-rv5j1201	1643	32	.	.	.
cord-022561-rv5j1201	1644	1	Viruses	virus	NNS
cord-022561-rv5j1201	1644	2	,	,	,
cord-022561-rv5j1201	1644	3	bacteria	bacteria	NNS
cord-022561-rv5j1201	1644	4	,	,	,
cord-022561-rv5j1201	1644	5	and	and	CC
cord-022561-rv5j1201	1644	6	particles	particle	NNS
cord-022561-rv5j1201	1644	7	arriving	arrive	VBG
cord-022561-rv5j1201	1644	8	in	in	IN
cord-022561-rv5j1201	1644	9	the	the	DT
cord-022561-rv5j1201	1644	10	lymph	lymph	NN
cord-022561-rv5j1201	1644	11	and	and	CC
cord-022561-rv5j1201	1644	12	blood	blood	NN
cord-022561-rv5j1201	1644	13	interact	interact	VBP
cord-022561-rv5j1201	1644	14	with	with	IN
cord-022561-rv5j1201	1644	15	cells	cell	NNS
cord-022561-rv5j1201	1644	16	of	of	IN
cord-022561-rv5j1201	1644	17	the	the	DT
cord-022561-rv5j1201	1644	18	monocyte	monocyte	JJ
cord-022561-rv5j1201	1644	19	-	-	HYPH
cord-022561-rv5j1201	1644	20	macrophage	macrophage	NN
cord-022561-rv5j1201	1644	21	system	system	NN
cord-022561-rv5j1201	1644	22	through	through	IN
cord-022561-rv5j1201	1644	23	phagocytosis	phagocytosis	NN
cord-022561-rv5j1201	1644	24	and	and	CC
cord-022561-rv5j1201	1644	25	antigen	antigen	NN
cord-022561-rv5j1201	1644	26	processing	processing	NN
cord-022561-rv5j1201	1644	27	and	and	CC
cord-022561-rv5j1201	1644	28	presentation	presentation	NN
cord-022561-rv5j1201	1644	29	.	.	.
cord-022561-rv5j1201	1645	1	Hyperplasia	hyperplasia	NN
cord-022561-rv5j1201	1645	2	of	of	IN
cord-022561-rv5j1201	1645	3	the	the	DT
cord-022561-rv5j1201	1645	4	macrophages	macrophage	NNS
cord-022561-rv5j1201	1645	5	often	often	RB
cord-022561-rv5j1201	1645	6	occurs	occur	VBZ
cord-022561-rv5j1201	1645	7	concurrently	concurrently	RB
cord-022561-rv5j1201	1645	8	.	.	.
cord-022561-rv5j1201	1646	1	Antigen	antigen	NN
cord-022561-rv5j1201	1646	2	processing	processing	NN
cord-022561-rv5j1201	1646	3	and	and	CC
cord-022561-rv5j1201	1646	4	presentation	presentation	NN
cord-022561-rv5j1201	1646	5	are	be	VBP
cord-022561-rv5j1201	1646	6	followed	follow	VBN
cord-022561-rv5j1201	1646	7	by	by	IN
cord-022561-rv5j1201	1646	8	an	an	DT
cord-022561-rv5j1201	1646	9	immune	immune	JJ
cord-022561-rv5j1201	1646	10	response	response	NN
cord-022561-rv5j1201	1646	11	resulting	result	VBG
cord-022561-rv5j1201	1646	12	in	in	IN
cord-022561-rv5j1201	1646	13	proliferation	proliferation	NN
cord-022561-rv5j1201	1646	14	of	of	IN
cord-022561-rv5j1201	1646	15	B	b	NN
cord-022561-rv5j1201	1646	16	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	1646	17	,	,	,
cord-022561-rv5j1201	1646	18	plasma	plasma	NN
cord-022561-rv5j1201	1646	19	cells	cell	NNS
cord-022561-rv5j1201	1646	20	,	,	,
cord-022561-rv5j1201	1646	21	and	and	CC
cord-022561-rv5j1201	1646	22	the	the	DT
cord-022561-rv5j1201	1646	23	subsequent	subsequent	JJ
cord-022561-rv5j1201	1646	24	production	production	NN
cord-022561-rv5j1201	1646	25	of	of	IN
cord-022561-rv5j1201	1646	26	antibody	antibody	NN
cord-022561-rv5j1201	1646	27	;	;	:
cord-022561-rv5j1201	1646	28	proliferation	proliferation	NN
cord-022561-rv5j1201	1646	29	of	of	IN
cord-022561-rv5j1201	1646	30	T	t	NN
cord-022561-rv5j1201	1646	31	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	1646	32	may	may	MD
cord-022561-rv5j1201	1646	33	also	also	RB
cord-022561-rv5j1201	1646	34	occur	occur	VB
cord-022561-rv5j1201	1646	35	.	.	.
cord-022561-rv5j1201	1647	1	The	the	DT
cord-022561-rv5j1201	1647	2	relationships	relationship	NNS
cord-022561-rv5j1201	1647	3	between	between	IN
cord-022561-rv5j1201	1647	4	anatomic	anatomic	JJ
cord-022561-rv5j1201	1647	5	structures	structure	NNS
cord-022561-rv5j1201	1647	6	and	and	CC
cord-022561-rv5j1201	1647	7	the	the	DT
cord-022561-rv5j1201	1647	8	different	different	JJ
cord-022561-rv5j1201	1647	9	functions	function	NNS
cord-022561-rv5j1201	1647	10	of	of	IN
cord-022561-rv5j1201	1647	11	the	the	DT
cord-022561-rv5j1201	1647	12	spleen	spleen	NNS
cord-022561-rv5j1201	1647	13	are	be	VBP
cord-022561-rv5j1201	1647	14	complicated	complicated	JJ
cord-022561-rv5j1201	1647	15	.	.	.
cord-022561-rv5j1201	1648	1	There	there	EX
cord-022561-rv5j1201	1648	2	are	be	VBP
cord-022561-rv5j1201	1648	3	also	also	RB
cord-022561-rv5j1201	1648	4	anatomic	anatomic	JJ
cord-022561-rv5j1201	1648	5	differences	difference	NNS
cord-022561-rv5j1201	1648	6	among	among	IN
cord-022561-rv5j1201	1648	7	domestic	domestic	JJ
cord-022561-rv5j1201	1648	8	animal	animal	NN
cord-022561-rv5j1201	1648	9	species	specie	NNS
cord-022561-rv5j1201	1648	10	and	and	CC
cord-022561-rv5j1201	1648	11	confusion	confusion	NN
cord-022561-rv5j1201	1648	12	about	about	IN
cord-022561-rv5j1201	1648	13	the	the	DT
cord-022561-rv5j1201	1648	14	correct	correct	JJ
cord-022561-rv5j1201	1648	15	and	and	CC
cord-022561-rv5j1201	1648	16	up	up	RB
cord-022561-rv5j1201	1648	17	-	-	HYPH
cord-022561-rv5j1201	1648	18	to	to	IN
cord-022561-rv5j1201	1648	19	-	-	HYPH
cord-022561-rv5j1201	1648	20	date	date	NN
cord-022561-rv5j1201	1648	21	terminology	terminology	NN
cord-022561-rv5j1201	1648	22	.	.	.
cord-022561-rv5j1201	1649	1	The	the	DT
cord-022561-rv5j1201	1649	2	following	follow	VBG
cord-022561-rv5j1201	1649	3	brief	brief	JJ
cord-022561-rv5j1201	1649	4	discussion	discussion	NN
cord-022561-rv5j1201	1649	5	 	 	_SP
cord-022561-rv5j1201	1649	6	MALT	MALT	NNP
cord-022561-rv5j1201	1649	7	,	,	,
cord-022561-rv5j1201	1649	8	Mucosa	Mucosa	NNP
cord-022561-rv5j1201	1649	9	-	-	HYPH
cord-022561-rv5j1201	1649	10	associated	associate	VBN
cord-022561-rv5j1201	1649	11	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	1649	12	tissue	tissue	NN
cord-022561-rv5j1201	1649	13	.	.	.
cord-022561-rv5j1201	1650	1	4	4	LS
cord-022561-rv5j1201	1651	1	There	there	EX
cord-022561-rv5j1201	1651	2	are	be	VBP
cord-022561-rv5j1201	1651	3	numerous	numerous	JJ
cord-022561-rv5j1201	1651	4	synonyms	synonyms	NN
cord-022561-rv5j1201	1651	5	and	and	CC
cord-022561-rv5j1201	1651	6	misuse	misuse	NN
cord-022561-rv5j1201	1651	7	of	of	IN
cord-022561-rv5j1201	1651	8	terms	term	NNS
cord-022561-rv5j1201	1651	9	within	within	IN
cord-022561-rv5j1201	1651	10	the	the	DT
cord-022561-rv5j1201	1651	11	literature	literature	NN
cord-022561-rv5j1201	1651	12	,	,	,
cord-022561-rv5j1201	1651	13	which	which	WDT
cord-022561-rv5j1201	1651	14	have	have	VBP
cord-022561-rv5j1201	1651	15	contributed	contribute	VBN
cord-022561-rv5j1201	1651	16	to	to	IN
cord-022561-rv5j1201	1651	17	the	the	DT
cord-022561-rv5j1201	1651	18	confusion	confusion	NN
cord-022561-rv5j1201	1651	19	over	over	IN
cord-022561-rv5j1201	1651	20	terminology	terminology	NN
cord-022561-rv5j1201	1651	21	for	for	IN
cord-022561-rv5j1201	1651	22	red	red	JJ
cord-022561-rv5j1201	1651	23	pulp	pulp	NN
cord-022561-rv5j1201	1651	24	vascular	vascular	JJ
cord-022561-rv5j1201	1651	25	spaces	space	NNS
cord-022561-rv5j1201	1651	26	.	.	.
cord-022561-rv5j1201	1652	1	These	these	DT
cord-022561-rv5j1201	1652	2	terms	term	NNS
cord-022561-rv5j1201	1652	3	include	include	VBP
cord-022561-rv5j1201	1652	4	reticular	reticular	JJ
cord-022561-rv5j1201	1652	5	space	space	NN
cord-022561-rv5j1201	1652	6	,	,	,
cord-022561-rv5j1201	1652	7	red	red	JJ
cord-022561-rv5j1201	1652	8	pulp	pulp	NN
cord-022561-rv5j1201	1652	9	,	,	,
cord-022561-rv5j1201	1652	10	splenic	splenic	JJ
cord-022561-rv5j1201	1652	11	cords	cord	NNS
cord-022561-rv5j1201	1652	12	,	,	,
cord-022561-rv5j1201	1652	13	sinuses	sinus	NNS
cord-022561-rv5j1201	1652	14	,	,	,
cord-022561-rv5j1201	1652	15	red	red	JJ
cord-022561-rv5j1201	1652	16	pulp	pulp	NN
cord-022561-rv5j1201	1652	17	sinuses	sinus	NNS
cord-022561-rv5j1201	1652	18	,	,	,
cord-022561-rv5j1201	1652	19	sinus	sinus	NN
cord-022561-rv5j1201	1652	20	spaces	space	NNS
cord-022561-rv5j1201	1652	21	,	,	,
cord-022561-rv5j1201	1652	22	pulp	pulp	NN
cord-022561-rv5j1201	1652	23	spaces	space	NNS
cord-022561-rv5j1201	1652	24	,	,	,
cord-022561-rv5j1201	1652	25	mesh	mesh	NN
cord-022561-rv5j1201	1652	26	space	space	NN
cord-022561-rv5j1201	1652	27	of	of	IN
cord-022561-rv5j1201	1652	28	the	the	DT
cord-022561-rv5j1201	1652	29	spleen	spleen	NN
cord-022561-rv5j1201	1652	30	,	,	,
cord-022561-rv5j1201	1652	31	reticular	reticular	JJ
cord-022561-rv5j1201	1652	32	cell	cell	NN
cord-022561-rv5j1201	1652	33	-	-	HYPH
cord-022561-rv5j1201	1652	34	lined	line	VBN
cord-022561-rv5j1201	1652	35	meshwork	meshwork	NN
cord-022561-rv5j1201	1652	36	,	,	,
cord-022561-rv5j1201	1652	37	interstices	interstice	NNS
cord-022561-rv5j1201	1652	38	of	of	IN
cord-022561-rv5j1201	1652	39	the	the	DT
cord-022561-rv5j1201	1652	40	reticulum	reticulum	NN
cord-022561-rv5j1201	1652	41	network	network	NN
cord-022561-rv5j1201	1652	42	,	,	,
cord-022561-rv5j1201	1652	43	bloodfilled	bloodfilled	JJ
cord-022561-rv5j1201	1652	44	reticular	reticular	JJ
cord-022561-rv5j1201	1652	45	meshwork	meshwork	NN
cord-022561-rv5j1201	1652	46	of	of	IN
cord-022561-rv5j1201	1652	47	the	the	DT
cord-022561-rv5j1201	1652	48	red	red	JJ
cord-022561-rv5j1201	1652	49	pulp	pulp	NN
cord-022561-rv5j1201	1652	50	,	,	,
cord-022561-rv5j1201	1652	51	chordal	chordal	JJ
cord-022561-rv5j1201	1652	52	spaces	space	NNS
cord-022561-rv5j1201	1652	53	,	,	,
cord-022561-rv5j1201	1652	54	splenic	splenic	JJ
cord-022561-rv5j1201	1652	55	cords	cord	NNS
cord-022561-rv5j1201	1652	56	,	,	,
cord-022561-rv5j1201	1652	57	and	and	CC
cord-022561-rv5j1201	1652	58	cords	cord	NNS
cord-022561-rv5j1201	1652	59	of	of	IN
cord-022561-rv5j1201	1652	60	Billroth	Billroth	NNP
cord-022561-rv5j1201	1652	61	.	.	.
cord-022561-rv5j1201	1653	1	The	the	DT
cord-022561-rv5j1201	1653	2	latter	latter	JJ
cord-022561-rv5j1201	1653	3	two	two	CD
cord-022561-rv5j1201	1653	4	terms	term	NNS
cord-022561-rv5j1201	1653	5	are	be	VBP
cord-022561-rv5j1201	1653	6	defined	define	VBN
cord-022561-rv5j1201	1653	7	as	as	IN
cord-022561-rv5j1201	1653	8	the	the	DT
cord-022561-rv5j1201	1653	9	red	red	JJ
cord-022561-rv5j1201	1653	10	pulp	pulp	NN
cord-022561-rv5j1201	1653	11	between	between	IN
cord-022561-rv5j1201	1653	12	the	the	DT
cord-022561-rv5j1201	1653	13	sinusoids	sinusoid	NNS
cord-022561-rv5j1201	1653	14	,	,	,
cord-022561-rv5j1201	1653	15	which	which	WDT
cord-022561-rv5j1201	1653	16	most	most	JJS
cord-022561-rv5j1201	1653	17	domestic	domestic	JJ
cord-022561-rv5j1201	1653	18	animals	animal	NNS
cord-022561-rv5j1201	1653	19	do	do	VBP
cord-022561-rv5j1201	1653	20	not	not	RB
cord-022561-rv5j1201	1653	21	have	have	VB
cord-022561-rv5j1201	1653	22	(	(	-LRB-
cord-022561-rv5j1201	1653	23	except	except	IN
cord-022561-rv5j1201	1653	24	the	the	DT
cord-022561-rv5j1201	1653	25	dog	dog	NN
cord-022561-rv5j1201	1653	26	)	)	-RRB-
cord-022561-rv5j1201	1653	27	.	.	.
cord-022561-rv5j1201	1654	1	Therefore	therefore	RB
cord-022561-rv5j1201	1654	2	the	the	DT
cord-022561-rv5j1201	1654	3	term	term	NN
cord-022561-rv5j1201	1654	4	red	red	JJ
cord-022561-rv5j1201	1654	5	pulp	pulp	NN
cord-022561-rv5j1201	1654	6	vascular	vascular	JJ
cord-022561-rv5j1201	1654	7	spaces	space	NNS
cord-022561-rv5j1201	1654	8	is	be	VBZ
cord-022561-rv5j1201	1654	9	more	more	RBR
cord-022561-rv5j1201	1654	10	appropriate	appropriate	JJ
cord-022561-rv5j1201	1654	11	.	.	.
cord-022561-rv5j1201	1655	1	As	as	IN
cord-022561-rv5j1201	1655	2	a	a	DT
cord-022561-rv5j1201	1655	3	result	result	NN
cord-022561-rv5j1201	1655	4	of	of	IN
cord-022561-rv5j1201	1655	5	this	this	DT
cord-022561-rv5j1201	1655	6	pattern	pattern	NN
cord-022561-rv5j1201	1655	7	of	of	IN
cord-022561-rv5j1201	1655	8	blood	blood	NN
cord-022561-rv5j1201	1655	9	flow	flow	NN
cord-022561-rv5j1201	1655	10	,	,	,
cord-022561-rv5j1201	1655	11	macrophages	macrophage	NNS
cord-022561-rv5j1201	1655	12	in	in	IN
cord-022561-rv5j1201	1655	13	the	the	DT
cord-022561-rv5j1201	1655	14	marginal	marginal	JJ
cord-022561-rv5j1201	1655	15	sinus	sinus	NN
cord-022561-rv5j1201	1655	16	have	have	VBP
cord-022561-rv5j1201	1655	17	the	the	DT
cord-022561-rv5j1201	1655	18	first	first	JJ
cord-022561-rv5j1201	1655	19	opportunity	opportunity	NN
cord-022561-rv5j1201	1655	20	to	to	TO
cord-022561-rv5j1201	1655	21	phagocytize	phagocytize	VB
cord-022561-rv5j1201	1655	22	antigens	antigen	NNS
cord-022561-rv5j1201	1655	23	,	,	,
cord-022561-rv5j1201	1655	24	bacteria	bacteria	NNS
cord-022561-rv5j1201	1655	25	,	,	,
cord-022561-rv5j1201	1655	26	particles	particle	NNS
cord-022561-rv5j1201	1655	27	,	,	,
cord-022561-rv5j1201	1655	28	and	and	CC
cord-022561-rv5j1201	1655	29	other	other	JJ
cord-022561-rv5j1201	1655	30	material	material	NN
cord-022561-rv5j1201	1655	31	before	before	IN
cord-022561-rv5j1201	1655	32	macrophages	macrophage	NNS
cord-022561-rv5j1201	1655	33	in	in	IN
cord-022561-rv5j1201	1655	34	the	the	DT
cord-022561-rv5j1201	1655	35	sinusoids	sinusoid	NNS
cord-022561-rv5j1201	1655	36	(	(	-LRB-
cord-022561-rv5j1201	1655	37	in	in	IN
cord-022561-rv5j1201	1655	38	the	the	DT
cord-022561-rv5j1201	1655	39	dog	dog	NN
cord-022561-rv5j1201	1655	40	)	)	-RRB-
cord-022561-rv5j1201	1655	41	or	or	CC
cord-022561-rv5j1201	1655	42	in	in	IN
cord-022561-rv5j1201	1655	43	the	the	DT
cord-022561-rv5j1201	1655	44	PAMS	PAMS	NNP
cord-022561-rv5j1201	1655	45	and	and	CC
cord-022561-rv5j1201	1655	46	red	red	JJ
cord-022561-rv5j1201	1655	47	pulp	pulp	NN
cord-022561-rv5j1201	1655	48	vascular	vascular	JJ
cord-022561-rv5j1201	1655	49	spaces	space	NNS
cord-022561-rv5j1201	1655	50	(	(	-LRB-
cord-022561-rv5j1201	1655	51	all	all	DT
cord-022561-rv5j1201	1655	52	other	other	JJ
cord-022561-rv5j1201	1655	53	domestic	domestic	JJ
cord-022561-rv5j1201	1655	54	animals	animal	NNS
cord-022561-rv5j1201	1655	55	)	)	-RRB-
cord-022561-rv5j1201	1655	56	.	.	.
cord-022561-rv5j1201	1656	1	In	in	IN
cord-022561-rv5j1201	1656	2	the	the	DT
cord-022561-rv5j1201	1656	3	dog	dog	NN
cord-022561-rv5j1201	1656	4	the	the	DT
cord-022561-rv5j1201	1656	5	marginal	marginal	JJ
cord-022561-rv5j1201	1656	6	sinus	sinus	NN
cord-022561-rv5j1201	1656	7	drains	drain	VBZ
cord-022561-rv5j1201	1656	8	into	into	IN
cord-022561-rv5j1201	1656	9	the	the	DT
cord-022561-rv5j1201	1656	10	sinusoids	sinusoid	NNS
cord-022561-rv5j1201	1656	11	,	,	,
cord-022561-rv5j1201	1656	12	but	but	CC
cord-022561-rv5j1201	1656	13	in	in	IN
cord-022561-rv5j1201	1656	14	other	other	JJ
cord-022561-rv5j1201	1656	15	domestic	domestic	JJ
cord-022561-rv5j1201	1656	16	animals	animal	NNS
cord-022561-rv5j1201	1656	17	it	-PRON-	PRP
cord-022561-rv5j1201	1656	18	drains	drain	VBZ
cord-022561-rv5j1201	1656	19	into	into	IN
cord-022561-rv5j1201	1656	20	the	the	DT
cord-022561-rv5j1201	1656	21	red	red	JJ
cord-022561-rv5j1201	1656	22	pulp	pulp	NN
cord-022561-rv5j1201	1656	23	vascular	vascular	JJ
cord-022561-rv5j1201	1656	24	spaces	space	NNS
cord-022561-rv5j1201	1656	25	.	.	.
cord-022561-rv5j1201	1657	1	The	the	DT
cord-022561-rv5j1201	1657	2	central	central	JJ
cord-022561-rv5j1201	1657	3	arteries	artery	NNS
cord-022561-rv5j1201	1657	4	leave	leave	VBP
cord-022561-rv5j1201	1657	5	the	the	DT
cord-022561-rv5j1201	1657	6	white	white	JJ
cord-022561-rv5j1201	1657	7	pulp	pulp	NN
cord-022561-rv5j1201	1657	8	,	,	,
cord-022561-rv5j1201	1657	9	enter	enter	VB
cord-022561-rv5j1201	1657	10	the	the	DT
cord-022561-rv5j1201	1657	11	red	red	JJ
cord-022561-rv5j1201	1657	12	pulp	pulp	NN
cord-022561-rv5j1201	1657	13	,	,	,
cord-022561-rv5j1201	1657	14	and	and	CC
cord-022561-rv5j1201	1657	15	branch	branch	NN
cord-022561-rv5j1201	1657	16	into	into	IN
cord-022561-rv5j1201	1657	17	smaller	small	JJR
cord-022561-rv5j1201	1657	18	penicillar	penicillar	NNS
cord-022561-rv5j1201	1657	19	arterioles	arteriole	NNS
cord-022561-rv5j1201	1657	20	.	.	.
cord-022561-rv5j1201	1658	1	Each	each	DT
cord-022561-rv5j1201	1658	2	arteriole	arteriole	NN
cord-022561-rv5j1201	1658	3	is	be	VBZ
cord-022561-rv5j1201	1658	4	surrounded	surround	VBN
cord-022561-rv5j1201	1658	5	by	by	IN
cord-022561-rv5j1201	1658	6	a	a	DT
cord-022561-rv5j1201	1658	7	sheath	sheath	NN
cord-022561-rv5j1201	1658	8	of	of	IN
cord-022561-rv5j1201	1658	9	macrophages	macrophage	NNS
cord-022561-rv5j1201	1658	10	known	know	VBN
cord-022561-rv5j1201	1658	11	as	as	IN
cord-022561-rv5j1201	1658	12	periarteriolar	periarteriolar	NNP
cord-022561-rv5j1201	1658	13	macrophage	macrophage	NN
cord-022561-rv5j1201	1658	14	sheaths	sheath	NNS
cord-022561-rv5j1201	1658	15	(	(	-LRB-
cord-022561-rv5j1201	1658	16	PAMS	PAMS	NNP
cord-022561-rv5j1201	1658	17	,	,	,
cord-022561-rv5j1201	1658	18	previously	previously	RB
cord-022561-rv5j1201	1658	19	known	know	VBN
cord-022561-rv5j1201	1658	20	as	as	IN
cord-022561-rv5j1201	1658	21	ellipsoids	ellipsoid	NNS
cord-022561-rv5j1201	1658	22	)	)	-RRB-
cord-022561-rv5j1201	1658	23	,	,	,
cord-022561-rv5j1201	1658	24	which	which	WDT
cord-022561-rv5j1201	1658	25	are	be	VBP
cord-022561-rv5j1201	1658	26	notably	notably	RB
cord-022561-rv5j1201	1658	27	prominent	prominent	JJ
cord-022561-rv5j1201	1658	28	in	in	IN
cord-022561-rv5j1201	1658	29	pigs	pig	NNS
cord-022561-rv5j1201	1658	30	,	,	,
cord-022561-rv5j1201	1658	31	dogs	dog	NNS
cord-022561-rv5j1201	1658	32	,	,	,
cord-022561-rv5j1201	1658	33	and	and	CC
cord-022561-rv5j1201	1658	34	cats	cat	NNS
cord-022561-rv5j1201	1658	35	.	.	.
cord-022561-rv5j1201	1659	1	In	in	IN
cord-022561-rv5j1201	1659	2	horses	horse	NNS
cord-022561-rv5j1201	1659	3	,	,	,
cord-022561-rv5j1201	1659	4	cattle	cattle	NNS
cord-022561-rv5j1201	1659	5	,	,	,
cord-022561-rv5j1201	1659	6	pigs	pig	NNS
cord-022561-rv5j1201	1659	7	,	,	,
cord-022561-rv5j1201	1659	8	and	and	CC
cord-022561-rv5j1201	1659	9	cats	cat	NNS
cord-022561-rv5j1201	1659	10	the	the	DT
cord-022561-rv5j1201	1659	11	terminal	terminal	JJ
cord-022561-rv5j1201	1659	12	branches	branch	NNS
cord-022561-rv5j1201	1659	13	of	of	IN
cord-022561-rv5j1201	1659	14	the	the	DT
cord-022561-rv5j1201	1659	15	penicillar	penicillar	NN
cord-022561-rv5j1201	1659	16	arterioles	arteriole	NNS
cord-022561-rv5j1201	1659	17	empty	empty	JJ
cord-022561-rv5j1201	1659	18	into	into	IN
cord-022561-rv5j1201	1659	19	the	the	DT
cord-022561-rv5j1201	1659	20	red	red	JJ
cord-022561-rv5j1201	1659	21	pulp	pulp	NN
cord-022561-rv5j1201	1659	22	vascular	vascular	JJ
cord-022561-rv5j1201	1659	23	spaces	space	NNS
cord-022561-rv5j1201	1659	24	lined	line	VBN
cord-022561-rv5j1201	1659	25	by	by	IN
cord-022561-rv5j1201	1659	26	reticular	reticular	JJ
cord-022561-rv5j1201	1659	27	cells	cell	NNS
cord-022561-rv5j1201	1659	28	.	.	.
cord-022561-rv5j1201	1660	1	Because	because	IN
cord-022561-rv5j1201	1660	2	the	the	DT
cord-022561-rv5j1201	1660	3	red	red	JJ
cord-022561-rv5j1201	1660	4	pulp	pulp	NN
cord-022561-rv5j1201	1660	5	vascular	vascular	JJ
cord-022561-rv5j1201	1660	6	spaces	space	NNS
cord-022561-rv5j1201	1660	7	are	be	VBP
cord-022561-rv5j1201	1660	8	not	not	RB
cord-022561-rv5j1201	1660	9	lined	line	VBN
cord-022561-rv5j1201	1660	10	by	by	IN
cord-022561-rv5j1201	1660	11	endothelium	endothelium	NN
cord-022561-rv5j1201	1660	12	,	,	,
cord-022561-rv5j1201	1660	13	this	this	DT
cord-022561-rv5j1201	1660	14	type	type	NN
cord-022561-rv5j1201	1660	15	of	of	IN
cord-022561-rv5j1201	1660	16	circulation	circulation	NN
cord-022561-rv5j1201	1660	17	is	be	VBZ
cord-022561-rv5j1201	1660	18	known	know	VBN
cord-022561-rv5j1201	1660	19	as	as	IN
cord-022561-rv5j1201	1660	20	an	an	DT
cord-022561-rv5j1201	1660	21	open	open	JJ
cord-022561-rv5j1201	1660	22	system	system	NN
cord-022561-rv5j1201	1660	23	.	.	.
cord-022561-rv5j1201	1661	1	This	this	DT
cord-022561-rv5j1201	1661	2	system	system	NN
cord-022561-rv5j1201	1661	3	is	be	VBZ
cord-022561-rv5j1201	1661	4	in	in	IN
cord-022561-rv5j1201	1661	5	contrast	contrast	NN
cord-022561-rv5j1201	1661	6	to	to	IN
cord-022561-rv5j1201	1661	7	the	the	DT
cord-022561-rv5j1201	1661	8	sinusoidal	sinusoidal	JJ
cord-022561-rv5j1201	1661	9	spleen	spleen	NNS
cord-022561-rv5j1201	1661	10	of	of	IN
cord-022561-rv5j1201	1661	11	the	the	DT
cord-022561-rv5j1201	1661	12	dog	dog	NN
cord-022561-rv5j1201	1661	13	(	(	-LRB-
cord-022561-rv5j1201	1661	14	also	also	RB
cord-022561-rv5j1201	1661	15	of	of	IN
cord-022561-rv5j1201	1661	16	the	the	DT
cord-022561-rv5j1201	1661	17	rat	rat	NN
cord-022561-rv5j1201	1661	18	and	and	CC
cord-022561-rv5j1201	1661	19	human	human	JJ
cord-022561-rv5j1201	1661	20	beings	being	NNS
cord-022561-rv5j1201	1661	21	)	)	-RRB-
cord-022561-rv5j1201	1661	22	,	,	,
cord-022561-rv5j1201	1661	23	where	where	WRB
cord-022561-rv5j1201	1661	24	the	the	DT
cord-022561-rv5j1201	1661	25	branches	branch	NNS
cord-022561-rv5j1201	1661	26	of	of	IN
cord-022561-rv5j1201	1661	27	the	the	DT
cord-022561-rv5j1201	1661	28	central	central	JJ
cord-022561-rv5j1201	1661	29	artery	artery	NN
cord-022561-rv5j1201	1661	30	of	of	IN
cord-022561-rv5j1201	1661	31	the	the	DT
cord-022561-rv5j1201	1661	32	white	white	JJ
cord-022561-rv5j1201	1661	33	pulp	pulp	NN
cord-022561-rv5j1201	1661	34	and	and	CC
cord-022561-rv5j1201	1661	35	vessels	vessel	NNS
cord-022561-rv5j1201	1661	36	from	from	IN
cord-022561-rv5j1201	1661	37	the	the	DT
cord-022561-rv5j1201	1661	38	marginal	marginal	JJ
cord-022561-rv5j1201	1661	39	sinus	sinus	NN
cord-022561-rv5j1201	1661	40	enter	enter	VB
cord-022561-rv5j1201	1661	41	into	into	IN
cord-022561-rv5j1201	1661	42	the	the	DT
cord-022561-rv5j1201	1661	43	sinusoids	sinusoid	NNS
cord-022561-rv5j1201	1661	44	,	,	,
cord-022561-rv5j1201	1661	45	which	which	WDT
cord-022561-rv5j1201	1661	46	are	be	VBP
cord-022561-rv5j1201	1661	47	lined	line	VBN
cord-022561-rv5j1201	1661	48	by	by	IN
cord-022561-rv5j1201	1661	49	a	a	DT
cord-022561-rv5j1201	1661	50	discontinuous	discontinuous	JJ
cord-022561-rv5j1201	1661	51	endothelium	endothelium	NN
cord-022561-rv5j1201	1661	52	,	,	,
cord-022561-rv5j1201	1661	53	and	and	CC
cord-022561-rv5j1201	1661	54	these	these	DT
cord-022561-rv5j1201	1661	55	empty	empty	JJ
cord-022561-rv5j1201	1661	56	into	into	IN
cord-022561-rv5j1201	1661	57	splenic	splenic	JJ
cord-022561-rv5j1201	1661	58	venules	venule	NNS
cord-022561-rv5j1201	1661	59	.	.	.
cord-022561-rv5j1201	1662	1	This	this	DT
cord-022561-rv5j1201	1662	2	type	type	NN
cord-022561-rv5j1201	1662	3	of	of	IN
cord-022561-rv5j1201	1662	4	circulation	circulation	NN
cord-022561-rv5j1201	1662	5	is	be	VBZ
cord-022561-rv5j1201	1662	6	known	know	VBN
cord-022561-rv5j1201	1662	7	as	as	IN
cord-022561-rv5j1201	1662	8	a	a	DT
cord-022561-rv5j1201	1662	9	closed	closed	JJ
cord-022561-rv5j1201	1662	10	system	system	NN
cord-022561-rv5j1201	1662	11	because	because	IN
cord-022561-rv5j1201	1662	12	the	the	DT
cord-022561-rv5j1201	1662	13	blood	blood	NN
cord-022561-rv5j1201	1662	14	flow	flow	NN
cord-022561-rv5j1201	1662	15	is	be	VBZ
cord-022561-rv5j1201	1662	16	through	through	IN
cord-022561-rv5j1201	1662	17	blood	blood	NN
cord-022561-rv5j1201	1662	18	vessels	vessel	NNS
cord-022561-rv5j1201	1662	19	(	(	-LRB-
cord-022561-rv5j1201	1662	20	arterioles	arteriole	NNS
cord-022561-rv5j1201	1662	21	,	,	,
cord-022561-rv5j1201	1662	22	capillaries	capillary	NNS
cord-022561-rv5j1201	1662	23	,	,	,
cord-022561-rv5j1201	1662	24	sinusoids	sinusoid	NNS
cord-022561-rv5j1201	1662	25	,	,	,
cord-022561-rv5j1201	1662	26	and	and	CC
cord-022561-rv5j1201	1662	27	venules	venule	NNS
cord-022561-rv5j1201	1662	28	)	)	-RRB-
cord-022561-rv5j1201	1662	29	,	,	,
cord-022561-rv5j1201	1662	30	all	all	DT
cord-022561-rv5j1201	1662	31	of	of	IN
cord-022561-rv5j1201	1662	32	which	which	WDT
cord-022561-rv5j1201	1662	33	are	be	VBP
cord-022561-rv5j1201	1662	34	lined	line	VBN
cord-022561-rv5j1201	1662	35	by	by	IN
cord-022561-rv5j1201	1662	36	endothelium	endothelium	NN
cord-022561-rv5j1201	1662	37	.	.	.
cord-022561-rv5j1201	1663	1	Although	although	IN
cord-022561-rv5j1201	1663	2	circulation	circulation	NN
cord-022561-rv5j1201	1663	3	in	in	IN
cord-022561-rv5j1201	1663	4	the	the	DT
cord-022561-rv5j1201	1663	5	red	red	JJ
cord-022561-rv5j1201	1663	6	pulp	pulp	NN
cord-022561-rv5j1201	1663	7	is	be	VBZ
cord-022561-rv5j1201	1663	8	anatomically	anatomically	RB
cord-022561-rv5j1201	1663	9	open	open	JJ
cord-022561-rv5j1201	1663	10	in	in	IN
cord-022561-rv5j1201	1663	11	nonsinusoidal	nonsinusoidal	JJ
cord-022561-rv5j1201	1663	12	spleens	spleen	NNS
cord-022561-rv5j1201	1663	13	,	,	,
cord-022561-rv5j1201	1663	14	under	under	IN
cord-022561-rv5j1201	1663	15	certain	certain	JJ
cord-022561-rv5j1201	1663	16	conditions	condition	NNS
cord-022561-rv5j1201	1663	17	(	(	-LRB-
cord-022561-rv5j1201	1663	18	e.g.	e.g.	RB
cord-022561-rv5j1201	1663	19	,	,	,
cord-022561-rv5j1201	1663	20	during	during	IN
cord-022561-rv5j1201	1663	21	splenic	splenic	JJ
cord-022561-rv5j1201	1663	22	contraction	contraction	NN
cord-022561-rv5j1201	1663	23	)	)	-RRB-
cord-022561-rv5j1201	1663	24	the	the	DT
cord-022561-rv5j1201	1663	25	circulation	circulation	NN
cord-022561-rv5j1201	1663	26	is	be	VBZ
cord-022561-rv5j1201	1663	27	functionally	functionally	RB
cord-022561-rv5j1201	1663	28	closed	closed	JJ
cord-022561-rv5j1201	1663	29	,	,	,
cord-022561-rv5j1201	1663	30	and	and	CC
cord-022561-rv5j1201	1663	31	the	the	DT
cord-022561-rv5j1201	1663	32	blood	blood	NN
cord-022561-rv5j1201	1663	33	in	in	IN
cord-022561-rv5j1201	1663	34	the	the	DT
cord-022561-rv5j1201	1663	35	red	red	JJ
cord-022561-rv5j1201	1663	36	pulp	pulp	NN
cord-022561-rv5j1201	1663	37	is	be	VBZ
cord-022561-rv5j1201	1663	38	particulate	particulate	JJ
cord-022561-rv5j1201	1663	39	matter	matter	NN
cord-022561-rv5j1201	1663	40	and	and	CC
cord-022561-rv5j1201	1663	41	senescent	senescent	JJ
cord-022561-rv5j1201	1663	42	cells	cell	NNS
cord-022561-rv5j1201	1663	43	;	;	,
cord-022561-rv5j1201	1663	44	(	(	-LRB-
cord-022561-rv5j1201	1663	45	2	2	LS
cord-022561-rv5j1201	1663	46	)	)	-RRB-
cord-022561-rv5j1201	1663	47	transporting	transport	VBG
cord-022561-rv5j1201	1663	48	recirculating	recirculate	VBG
cord-022561-rv5j1201	1663	49	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	1663	50	and	and	CC
cord-022561-rv5j1201	1663	51	naïve	naïve	JJ
cord-022561-rv5j1201	1663	52	B	B	NNP
cord-022561-rv5j1201	1663	53	and	and	CC
cord-022561-rv5j1201	1663	54	T	t	NN
cord-022561-rv5j1201	1663	55	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	1663	56	to	to	IN
cord-022561-rv5j1201	1663	57	the	the	DT
cord-022561-rv5j1201	1663	58	follicle	follicle	NN
cord-022561-rv5j1201	1663	59	and	and	CC
cord-022561-rv5j1201	1663	60	PALS	pals	NN
cord-022561-rv5j1201	1663	61	,	,	,
cord-022561-rv5j1201	1663	62	respectively	respectively	RB
cord-022561-rv5j1201	1663	63	,	,	,
cord-022561-rv5j1201	1663	64	to	to	TO
cord-022561-rv5j1201	1663	65	fulfill	fulfill	VB
cord-022561-rv5j1201	1663	66	their	-PRON-	PRP$
cord-022561-rv5j1201	1663	67	specific	specific	JJ
cord-022561-rv5j1201	1663	68	immune	immune	JJ
cord-022561-rv5j1201	1663	69	functions	function	NNS
cord-022561-rv5j1201	1663	70	;	;	:
cord-022561-rv5j1201	1663	71	and	and	CC
cord-022561-rv5j1201	1663	72	(	(	-LRB-
cord-022561-rv5j1201	1663	73	3	3	LS
cord-022561-rv5j1201	1663	74	)	)	-RRB-
cord-022561-rv5j1201	1663	75	storage	storage	NN
cord-022561-rv5j1201	1663	76	of	of	IN
cord-022561-rv5j1201	1663	77	blood	blood	NN
cord-022561-rv5j1201	1663	78	in	in	IN
cord-022561-rv5j1201	1663	79	some	some	DT
cord-022561-rv5j1201	1663	80	domestic	domestic	JJ
cord-022561-rv5j1201	1663	81	animal	animal	NN
cord-022561-rv5j1201	1663	82	species	specie	NNS
cord-022561-rv5j1201	1663	83	(	(	-LRB-
cord-022561-rv5j1201	1663	84	dog	dog	NN
cord-022561-rv5j1201	1663	85	,	,	,
cord-022561-rv5j1201	1663	86	cat	cat	NN
cord-022561-rv5j1201	1663	87	,	,	,
cord-022561-rv5j1201	1663	88	and	and	CC
cord-022561-rv5j1201	1663	89	horse	horse	NN
cord-022561-rv5j1201	1663	90	)	)	-RRB-
cord-022561-rv5j1201	1664	1	(	(	-LRB-
cord-022561-rv5j1201	1664	2	Fig	Fig	NNP
cord-022561-rv5j1201	1664	3	.	.	.
cord-022561-rv5j1201	1665	1	13	13	CD
cord-022561-rv5j1201	1665	2	-	-	SYM
cord-022561-rv5j1201	1665	3	41	41	CD
cord-022561-rv5j1201	1665	4	)	)	-RRB-
cord-022561-rv5j1201	1665	5	.	.	.
cord-022561-rv5j1201	1666	1	Phagocytosis	Phagocytosis	NNP
cord-022561-rv5j1201	1666	2	is	be	VBZ
cord-022561-rv5j1201	1666	3	particularly	particularly	RB
cord-022561-rv5j1201	1666	4	effective	effective	JJ
cord-022561-rv5j1201	1666	5	in	in	IN
cord-022561-rv5j1201	1666	6	the	the	DT
cord-022561-rv5j1201	1666	7	spleen	spleen	NN
cord-022561-rv5j1201	1666	8	because	because	IN
cord-022561-rv5j1201	1666	9	blood	blood	NN
cord-022561-rv5j1201	1666	10	flows	flow	VBZ
cord-022561-rv5j1201	1666	11	through	through	IN
cord-022561-rv5j1201	1666	12	areas	area	NNS
cord-022561-rv5j1201	1666	13	within	within	IN
cord-022561-rv5j1201	1666	14	the	the	DT
cord-022561-rv5j1201	1666	15	red	red	JJ
cord-022561-rv5j1201	1666	16	pulp	pulp	NN
cord-022561-rv5j1201	1666	17	that	that	WDT
cord-022561-rv5j1201	1666	18	are	be	VBP
cord-022561-rv5j1201	1666	19	populated	populate	VBN
cord-022561-rv5j1201	1666	20	with	with	IN
cord-022561-rv5j1201	1666	21	increased	increase	VBN
cord-022561-rv5j1201	1666	22	concentrations	concentration	NNS
cord-022561-rv5j1201	1666	23	of	of	IN
cord-022561-rv5j1201	1666	24	macrophages	macrophage	NNS
cord-022561-rv5j1201	1666	25	,	,	,
cord-022561-rv5j1201	1666	26	namely	namely	RB
cord-022561-rv5j1201	1666	27	,	,	,
cord-022561-rv5j1201	1666	28	within	within	IN
cord-022561-rv5j1201	1666	29	the	the	DT
cord-022561-rv5j1201	1666	30	marginal	marginal	JJ
cord-022561-rv5j1201	1666	31	sinuses	sinus	NNS
cord-022561-rv5j1201	1666	32	,	,	,
cord-022561-rv5j1201	1666	33	in	in	IN
cord-022561-rv5j1201	1666	34	cuffs	cuff	NNS
cord-022561-rv5j1201	1666	35	around	around	IN
cord-022561-rv5j1201	1666	36	the	the	DT
cord-022561-rv5j1201	1666	37	penicillar	penicillar	JJ
cord-022561-rv5j1201	1666	38	arteries	artery	NNS
cord-022561-rv5j1201	1666	39	(	(	-LRB-
cord-022561-rv5j1201	1666	40	PAMS	PAMS	NNP
cord-022561-rv5j1201	1666	41	)	)	-RRB-
cord-022561-rv5j1201	1666	42	,	,	,
cord-022561-rv5j1201	1666	43	diffusely	diffusely	RB
cord-022561-rv5j1201	1666	44	on	on	IN
cord-022561-rv5j1201	1666	45	the	the	DT
cord-022561-rv5j1201	1666	46	reticular	reticular	JJ
cord-022561-rv5j1201	1666	47	walls	wall	NNS
cord-022561-rv5j1201	1666	48	of	of	IN
cord-022561-rv5j1201	1666	49	the	the	DT
cord-022561-rv5j1201	1666	50	red	red	JJ
cord-022561-rv5j1201	1666	51	pulp	pulp	NN
cord-022561-rv5j1201	1666	52	vascular	vascular	JJ
cord-022561-rv5j1201	1666	53	spaces	space	NNS
cord-022561-rv5j1201	1666	54	,	,	,
cord-022561-rv5j1201	1666	55	and	and	CC
cord-022561-rv5j1201	1666	56	along	along	IN
cord-022561-rv5j1201	1666	57	the	the	DT
cord-022561-rv5j1201	1666	58	sinusoids	sinusoid	NNS
cord-022561-rv5j1201	1666	59	in	in	IN
cord-022561-rv5j1201	1666	60	dogs	dog	NNS
cord-022561-rv5j1201	1666	61	.	.	.
cord-022561-rv5j1201	1667	1	Trafficking	trafficking	NN
cord-022561-rv5j1201	1667	2	of	of	IN
cord-022561-rv5j1201	1667	3	naïve	naïve	JJ
cord-022561-rv5j1201	1667	4	and	and	CC
cord-022561-rv5j1201	1667	5	recirculating	recirculating	JJ
cord-022561-rv5j1201	1667	6	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	1667	7	is	be	VBZ
cord-022561-rv5j1201	1667	8	facilitated	facilitate	VBN
cord-022561-rv5j1201	1667	9	by	by	IN
cord-022561-rv5j1201	1667	10	the	the	DT
cord-022561-rv5j1201	1667	11	proximity	proximity	NN
cord-022561-rv5j1201	1667	12	of	of	IN
cord-022561-rv5j1201	1667	13	the	the	DT
cord-022561-rv5j1201	1667	14	marginal	marginal	JJ
cord-022561-rv5j1201	1667	15	sinus	sinus	NN
cord-022561-rv5j1201	1667	16	to	to	IN
cord-022561-rv5j1201	1667	17	the	the	DT
cord-022561-rv5j1201	1667	18	follicular	follicular	JJ
cord-022561-rv5j1201	1667	19	germinal	germinal	JJ
cord-022561-rv5j1201	1667	20	centers	center	NNS
cord-022561-rv5j1201	1667	21	and	and	CC
cord-022561-rv5j1201	1667	22	PALS	pals	NN
cord-022561-rv5j1201	1667	23	.	.	.
cord-022561-rv5j1201	1668	1	Maps	map	NNS
cord-022561-rv5j1201	1668	2	of	of	IN
cord-022561-rv5j1201	1668	3	the	the	DT
cord-022561-rv5j1201	1668	4	vascular	vascular	JJ
cord-022561-rv5j1201	1668	5	blood	blood	NN
cord-022561-rv5j1201	1668	6	flow	flow	NN
cord-022561-rv5j1201	1668	7	in	in	IN
cord-022561-rv5j1201	1668	8	sinusoidal	sinusoidal	JJ
cord-022561-rv5j1201	1668	9	and	and	CC
cord-022561-rv5j1201	1668	10	nonsinusoidal	nonsinusoidal	JJ
cord-022561-rv5j1201	1668	11	spleens	spleen	NNS
cord-022561-rv5j1201	1668	12	are	be	VBP
cord-022561-rv5j1201	1668	13	illustrated	illustrate	VBN
cord-022561-rv5j1201	1668	14	in	in	IN
cord-022561-rv5j1201	1668	15	Figures	figure	NNS
cord-022561-rv5j1201	1668	16	13	13	CD
cord-022561-rv5j1201	1668	17	-	-	SYM
cord-022561-rv5j1201	1668	18	41	41	CD
cord-022561-rv5j1201	1668	19	to	to	TO
cord-022561-rv5j1201	1668	20	13	13	CD
cord-022561-rv5j1201	1668	21	-	-	SYM
cord-022561-rv5j1201	1668	22	43	43	CD
cord-022561-rv5j1201	1668	23	.	.	.
cord-022561-rv5j1201	1669	1	The	the	DT
cord-022561-rv5j1201	1669	2	celiac	celiac	JJ
cord-022561-rv5j1201	1669	3	artery	artery	NN
cord-022561-rv5j1201	1669	4	is	be	VBZ
cord-022561-rv5j1201	1669	5	the	the	DT
cord-022561-rv5j1201	1669	6	major	major	JJ
cord-022561-rv5j1201	1669	7	branch	branch	NN
cord-022561-rv5j1201	1669	8	of	of	IN
cord-022561-rv5j1201	1669	9	the	the	DT
cord-022561-rv5j1201	1669	10	abdominal	abdominal	JJ
cord-022561-rv5j1201	1669	11	aorta	aorta	NN
cord-022561-rv5j1201	1669	12	from	from	IN
cord-022561-rv5j1201	1669	13	which	which	WDT
cord-022561-rv5j1201	1669	14	the	the	DT
cord-022561-rv5j1201	1669	15	splenic	splenic	JJ
cord-022561-rv5j1201	1669	16	artery	artery	NN
cord-022561-rv5j1201	1669	17	arises	arise	VBZ
cord-022561-rv5j1201	1669	18	.	.	.
cord-022561-rv5j1201	1670	1	The	the	DT
cord-022561-rv5j1201	1670	2	splenic	splenic	JJ
cord-022561-rv5j1201	1670	3	artery	artery	NN
cord-022561-rv5j1201	1670	4	enters	enter	VBZ
cord-022561-rv5j1201	1670	5	the	the	DT
cord-022561-rv5j1201	1670	6	splenic	splenic	JJ
cord-022561-rv5j1201	1670	7	capsule	capsule	NN
cord-022561-rv5j1201	1670	8	at	at	IN
cord-022561-rv5j1201	1670	9	the	the	DT
cord-022561-rv5j1201	1670	10	hilus	hilus	NNP
cord-022561-rv5j1201	1670	11	,	,	,
cord-022561-rv5j1201	1670	12	where	where	WRB
cord-022561-rv5j1201	1670	13	it	-PRON-	PRP
cord-022561-rv5j1201	1670	14	branches	branch	VBZ
cord-022561-rv5j1201	1670	15	and	and	CC
cord-022561-rv5j1201	1670	16	enters	enter	VBZ
cord-022561-rv5j1201	1670	17	the	the	DT
cord-022561-rv5j1201	1670	18	fibromuscular	fibromuscular	JJ
cord-022561-rv5j1201	1670	19	trabeculae	trabeculae	NNP
cord-022561-rv5j1201	1670	20	as	as	IN
cord-022561-rv5j1201	1670	21	trabecular	trabecular	JJ
cord-022561-rv5j1201	1670	22	arteries	artery	NNS
cord-022561-rv5j1201	1670	23	to	to	TO
cord-022561-rv5j1201	1670	24	supply	supply	VB
cord-022561-rv5j1201	1670	25	the	the	DT
cord-022561-rv5j1201	1670	26	splenic	splenic	JJ
cord-022561-rv5j1201	1670	27	parenchyma	parenchyma	NN
cord-022561-rv5j1201	1670	28	.	.	.
cord-022561-rv5j1201	1671	1	Trabecular	Trabecular	NNP
cord-022561-rv5j1201	1671	2	arteries	artery	NNS
cord-022561-rv5j1201	1671	3	become	become	VBP
cord-022561-rv5j1201	1671	4	the	the	DT
cord-022561-rv5j1201	1671	5	central	central	JJ
cord-022561-rv5j1201	1671	6	arteries	artery	NNS
cord-022561-rv5j1201	1671	7	of	of	IN
cord-022561-rv5j1201	1671	8	the	the	DT
cord-022561-rv5j1201	1671	9	white	white	JJ
cord-022561-rv5j1201	1671	10	pulp	pulp	NN
cord-022561-rv5j1201	1671	11	and	and	CC
cord-022561-rv5j1201	1671	12	are	be	VBP
cord-022561-rv5j1201	1671	13	surrounded	surround	VBN
cord-022561-rv5j1201	1671	14	by	by	IN
cord-022561-rv5j1201	1671	15	cuffs	cuff	NNS
cord-022561-rv5j1201	1671	16	of	of	IN
cord-022561-rv5j1201	1671	17	T	t	NN
cord-022561-rv5j1201	1671	18	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	1671	19	forming	form	VBG
cord-022561-rv5j1201	1671	20	the	the	DT
cord-022561-rv5j1201	1671	21	PALS	pals	NN
cord-022561-rv5j1201	1671	22	.	.	.
cord-022561-rv5j1201	1672	1	The	the	DT
cord-022561-rv5j1201	1672	2	splenic	splenic	JJ
cord-022561-rv5j1201	1672	3	follicles	follicle	NNS
cord-022561-rv5j1201	1672	4	,	,	,
cord-022561-rv5j1201	1672	5	populated	populate	VBN
cord-022561-rv5j1201	1672	6	by	by	IN
cord-022561-rv5j1201	1672	7	B	b	NN
cord-022561-rv5j1201	1672	8	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	1672	9	,	,	,
cord-022561-rv5j1201	1672	10	are	be	VBP
cord-022561-rv5j1201	1672	11	eccentrically	eccentrically	RB
cord-022561-rv5j1201	1672	12	embedded	embed	VBN
cord-022561-rv5j1201	1672	13	within	within	IN
cord-022561-rv5j1201	1672	14	or	or	CC
cord-022561-rv5j1201	1672	15	just	just	RB
cord-022561-rv5j1201	1672	16	adjacent	adjacent	JJ
cord-022561-rv5j1201	1672	17	to	to	IN
cord-022561-rv5j1201	1672	18	the	the	DT
cord-022561-rv5j1201	1672	19	PALS	pals	NN
cord-022561-rv5j1201	1672	20	.	.	.
cord-022561-rv5j1201	1673	1	The	the	DT
cord-022561-rv5j1201	1673	2	central	central	JJ
cord-022561-rv5j1201	1673	3	arteries	artery	NNS
cord-022561-rv5j1201	1673	4	send	send	VBP
cord-022561-rv5j1201	1673	5	branches	branch	NNS
cord-022561-rv5j1201	1673	6	-	-	:
cord-022561-rv5j1201	1673	7	the	the	DT
cord-022561-rv5j1201	1673	8	radial	radial	JJ
cord-022561-rv5j1201	1673	9	arteries	artery	NNS
cord-022561-rv5j1201	1673	10	-	-	:
cord-022561-rv5j1201	1673	11	to	to	TO
cord-022561-rv5j1201	1673	12	supply	supply	VB
cord-022561-rv5j1201	1673	13	the	the	DT
cord-022561-rv5j1201	1673	14	marginal	marginal	JJ
cord-022561-rv5j1201	1673	15	sinus	sinus	NN
cord-022561-rv5j1201	1673	16	surrounding	surround	VBG
cord-022561-rv5j1201	1673	17	the	the	DT
cord-022561-rv5j1201	1673	18	splenic	splenic	JJ
cord-022561-rv5j1201	1673	19	follicles	follicle	NNS
cord-022561-rv5j1201	1673	20	.	.	.
cord-022561-rv5j1201	1674	1	Thus	thus	RB
cord-022561-rv5j1201	1674	2	the	the	DT
cord-022561-rv5j1201	1674	3	cells	cell	NNS
cord-022561-rv5j1201	1674	4	at	at	IN
cord-022561-rv5j1201	1674	5	the	the	DT
cord-022561-rv5j1201	1674	6	circumferences	circumference	NNS
cord-022561-rv5j1201	1674	7	of	of	IN
cord-022561-rv5j1201	1674	8	the	the	DT
cord-022561-rv5j1201	1674	9	follicles	follicle	NNS
cord-022561-rv5j1201	1674	10	are	be	VBP
cord-022561-rv5j1201	1674	11	brought	bring	VBN
cord-022561-rv5j1201	1674	12	into	into	IN
cord-022561-rv5j1201	1674	13	intimate	intimate	JJ
cord-022561-rv5j1201	1674	14	contact	contact	NN
cord-022561-rv5j1201	1674	15	with	with	IN
cord-022561-rv5j1201	1674	16	blood	blood	NN
cord-022561-rv5j1201	1674	17	-	-	HYPH
cord-022561-rv5j1201	1674	18	borne	bear	VBN
cord-022561-rv5j1201	1674	19	antigens	antigen	NNS
cord-022561-rv5j1201	1674	20	and	and	CC
cord-022561-rv5j1201	1674	21	trafficking	traffic	VBG
cord-022561-rv5j1201	1674	22	B	b	NN
cord-022561-rv5j1201	1674	23	and	and	CC
cord-022561-rv5j1201	1674	24	T	t	NN
cord-022561-rv5j1201	1674	25	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	1674	26	in	in	IN
cord-022561-rv5j1201	1674	27	the	the	DT
cord-022561-rv5j1201	1674	28	marginal	marginal	JJ
cord-022561-rv5j1201	1674	29	sinus	sinus	NN
cord-022561-rv5j1201	1674	30	.	.	.
cord-022561-rv5j1201	1675	1	diverted	divert	VBN
cord-022561-rv5j1201	1675	2	into	into	IN
cord-022561-rv5j1201	1675	3	"	"	``
cord-022561-rv5j1201	1675	4	channels	channel	NNS
cord-022561-rv5j1201	1675	5	"	"	''
cord-022561-rv5j1201	1675	6	lined	line	VBN
cord-022561-rv5j1201	1675	7	by	by	IN
cord-022561-rv5j1201	1675	8	reticular	reticular	JJ
cord-022561-rv5j1201	1675	9	cells	cell	NNS
cord-022561-rv5j1201	1675	10	.	.	.
cord-022561-rv5j1201	1676	1	Because	because	IN
cord-022561-rv5j1201	1676	2	the	the	DT
cord-022561-rv5j1201	1676	3	dog	dog	NN
cord-022561-rv5j1201	1676	4	has	have	VBZ
cord-022561-rv5j1201	1676	5	both	both	DT
cord-022561-rv5j1201	1676	6	sinusoids	sinusoid	NNS
cord-022561-rv5j1201	1676	7	and	and	CC
cord-022561-rv5j1201	1676	8	red	red	JJ
cord-022561-rv5j1201	1676	9	pulp	pulp	NN
cord-022561-rv5j1201	1676	10	vascular	vascular	JJ
cord-022561-rv5j1201	1676	11	spaces	space	NNS
cord-022561-rv5j1201	1676	12	,	,	,
cord-022561-rv5j1201	1676	13	it	-PRON-	PRP
cord-022561-rv5j1201	1676	14	has	have	VBZ
cord-022561-rv5j1201	1676	15	both	both	CC
cord-022561-rv5j1201	1676	16	open	open	JJ
cord-022561-rv5j1201	1676	17	and	and	CC
cord-022561-rv5j1201	1676	18	closed	closed	JJ
cord-022561-rv5j1201	1676	19	splenic	splenic	JJ
cord-022561-rv5j1201	1676	20	circulations	circulation	NNS
cord-022561-rv5j1201	1676	21	,	,	,
cord-022561-rv5j1201	1676	22	which	which	WDT
cord-022561-rv5j1201	1676	23	may	may	MD
cord-022561-rv5j1201	1676	24	allow	allow	VB
cord-022561-rv5j1201	1676	25	for	for	IN
cord-022561-rv5j1201	1676	26	both	both	CC
cord-022561-rv5j1201	1676	27	fast	fast	JJ
cord-022561-rv5j1201	1676	28	and	and	CC
cord-022561-rv5j1201	1676	29	slow	slow	JJ
cord-022561-rv5j1201	1676	30	flows	flow	NNS
cord-022561-rv5j1201	1676	31	of	of	IN
cord-022561-rv5j1201	1676	32	blood	blood	NN
cord-022561-rv5j1201	1676	33	depending	depend	VBG
cord-022561-rv5j1201	1676	34	on	on	IN
cord-022561-rv5j1201	1676	35	the	the	DT
cord-022561-rv5j1201	1676	36	physiologic	physiologic	JJ
cord-022561-rv5j1201	1676	37	need	need	NN
cord-022561-rv5j1201	1676	38	of	of	IN
cord-022561-rv5j1201	1676	39	the	the	DT
cord-022561-rv5j1201	1676	40	animal	animal	NN
cord-022561-rv5j1201	1676	41	.	.	.
cord-022561-rv5j1201	1677	1	Blood	blood	NN
cord-022561-rv5j1201	1677	2	flowing	flow	VBG
cord-022561-rv5j1201	1677	3	through	through	IN
cord-022561-rv5j1201	1677	4	the	the	DT
cord-022561-rv5j1201	1677	5	sinusoids	sinusoid	NNS
cord-022561-rv5j1201	1677	6	or	or	CC
cord-022561-rv5j1201	1677	7	red	red	JJ
cord-022561-rv5j1201	1677	8	pulp	pulp	NN
cord-022561-rv5j1201	1677	9	vascular	vascular	JJ
cord-022561-rv5j1201	1677	10	spaces	space	NNS
cord-022561-rv5j1201	1677	11	is	be	VBZ
cord-022561-rv5j1201	1677	12	under	under	IN
cord-022561-rv5j1201	1677	13	the	the	DT
cord-022561-rv5j1201	1677	14	surveillance	surveillance	NN
cord-022561-rv5j1201	1677	15	of	of	IN
cord-022561-rv5j1201	1677	16	macrophages	macrophage	NNS
cord-022561-rv5j1201	1677	17	.	.	.
cord-022561-rv5j1201	1678	1	In	in	IN
cord-022561-rv5j1201	1678	2	dogs	dog	NNS
cord-022561-rv5j1201	1678	3	the	the	DT
cord-022561-rv5j1201	1678	4	pseudopodia	pseudopodium	NNS
cord-022561-rv5j1201	1678	5	of	of	IN
cord-022561-rv5j1201	1678	6	these	these	DT
cord-022561-rv5j1201	1678	7	perisinusoidal	perisinusoidal	JJ
cord-022561-rv5j1201	1678	8	macrophages	macrophage	NNS
cord-022561-rv5j1201	1678	9	project	project	VBP
cord-022561-rv5j1201	1678	10	into	into	IN
cord-022561-rv5j1201	1678	11	the	the	DT
cord-022561-rv5j1201	1678	12	sinusoidal	sinusoidal	JJ
cord-022561-rv5j1201	1678	13	lumen	lumen	NN
cord-022561-rv5j1201	1678	14	through	through	IN
cord-022561-rv5j1201	1678	15	the	the	DT
cord-022561-rv5j1201	1678	16	spaces	space	NNS
cord-022561-rv5j1201	1678	17	in	in	IN
cord-022561-rv5j1201	1678	18	the	the	DT
cord-022561-rv5j1201	1678	19	discontinuous	discontinuous	JJ
cord-022561-rv5j1201	1678	20	endothelium	endothelium	NN
cord-022561-rv5j1201	1678	21	.	.	.
cord-022561-rv5j1201	1679	1	In	in	IN
cord-022561-rv5j1201	1679	2	all	all	DT
cord-022561-rv5j1201	1679	3	domestic	domestic	JJ
cord-022561-rv5j1201	1679	4	animals	animal	NNS
cord-022561-rv5j1201	1679	5	,	,	,
cord-022561-rv5j1201	1679	6	blood	blood	NN
cord-022561-rv5j1201	1679	7	in	in	IN
cord-022561-rv5j1201	1679	8	the	the	DT
cord-022561-rv5j1201	1679	9	red	red	JJ
cord-022561-rv5j1201	1679	10	pulp	pulp	NN
cord-022561-rv5j1201	1679	11	vascular	vascular	JJ
cord-022561-rv5j1201	1679	12	spaces	space	NNS
cord-022561-rv5j1201	1679	13	is	be	VBZ
cord-022561-rv5j1201	1679	14	under	under	IN
cord-022561-rv5j1201	1679	15	surveillance	surveillance	NN
cord-022561-rv5j1201	1679	16	of	of	IN
cord-022561-rv5j1201	1679	17	macrophages	macrophage	NNS
cord-022561-rv5j1201	1679	18	attached	attach	VBN
cord-022561-rv5j1201	1679	19	to	to	IN
cord-022561-rv5j1201	1679	20	the	the	DT
cord-022561-rv5j1201	1679	21	reticular	reticular	JJ
cord-022561-rv5j1201	1679	22	walls	wall	NNS
cord-022561-rv5j1201	1679	23	.	.	.
cord-022561-rv5j1201	1680	1	Blood	blood	NN
cord-022561-rv5j1201	1680	2	from	from	IN
cord-022561-rv5j1201	1680	3	the	the	DT
cord-022561-rv5j1201	1680	4	red	red	JJ
cord-022561-rv5j1201	1680	5	pulp	pulp	NN
cord-022561-rv5j1201	1680	6	vascular	vascular	JJ
cord-022561-rv5j1201	1680	7	spaces	space	NNS
cord-022561-rv5j1201	1680	8	and	and	CC
cord-022561-rv5j1201	1680	9	sinusoids	sinusoid	NNS
cord-022561-rv5j1201	1680	10	then	then	RB
cord-022561-rv5j1201	1680	11	drains	drain	VBZ
cord-022561-rv5j1201	1680	12	into	into	IN
cord-022561-rv5j1201	1680	13	the	the	DT
cord-022561-rv5j1201	1680	14	splenic	splenic	JJ
cord-022561-rv5j1201	1680	15	venules	venule	NNS
cord-022561-rv5j1201	1680	16	,	,	,
cord-022561-rv5j1201	1680	17	splenic	splenic	JJ
cord-022561-rv5j1201	1680	18	veins	vein	NNS
cord-022561-rv5j1201	1680	19	,	,	,
cord-022561-rv5j1201	1680	20	and	and	CC
cord-022561-rv5j1201	1680	21	ultimately	ultimately	RB
cord-022561-rv5j1201	1680	22	into	into	IN
cord-022561-rv5j1201	1680	23	the	the	DT
cord-022561-rv5j1201	1680	24	portal	portal	JJ
cord-022561-rv5j1201	1680	25	vein	vein	NN
cord-022561-rv5j1201	1680	26	,	,	,
cord-022561-rv5j1201	1680	27	which	which	WDT
cord-022561-rv5j1201	1680	28	empties	empty	VBZ
cord-022561-rv5j1201	1680	29	into	into	IN
cord-022561-rv5j1201	1680	30	the	the	DT
cord-022561-rv5j1201	1680	31	liver	liver	NN
cord-022561-rv5j1201	1680	32	.	.	.
cord-022561-rv5j1201	1681	1	The	the	DT
cord-022561-rv5j1201	1681	2	spleen	spleen	NN
cord-022561-rv5j1201	1681	3	filters	filter	VBZ
cord-022561-rv5j1201	1681	4	blood	blood	NN
cord-022561-rv5j1201	1681	5	and	and	CC
cord-022561-rv5j1201	1681	6	removes	remove	VBZ
cord-022561-rv5j1201	1681	7	foreign	foreign	JJ
cord-022561-rv5j1201	1681	8	particles	particle	NNS
cord-022561-rv5j1201	1681	9	,	,	,
cord-022561-rv5j1201	1681	10	bacteria	bacteria	NNS
cord-022561-rv5j1201	1681	11	,	,	,
cord-022561-rv5j1201	1681	12	and	and	CC
cord-022561-rv5j1201	1681	13	erythrocytes	erythrocyte	NNS
cord-022561-rv5j1201	1681	14	that	that	WDT
cord-022561-rv5j1201	1681	15	are	be	VBP
cord-022561-rv5j1201	1681	16	senescent	senescent	JJ
cord-022561-rv5j1201	1681	17	,	,	,
cord-022561-rv5j1201	1681	18	have	have	VBP
cord-022561-rv5j1201	1681	19	structural	structural	JJ
cord-022561-rv5j1201	1681	20	membrane	membrane	NN
cord-022561-rv5j1201	1681	21	abnormalities	abnormality	NNS
cord-022561-rv5j1201	1681	22	,	,	,
cord-022561-rv5j1201	1681	23	or	or	CC
cord-022561-rv5j1201	1681	24	are	be	VBP
cord-022561-rv5j1201	1681	25	infected	infect	VBN
cord-022561-rv5j1201	1681	26	with	with	IN
cord-022561-rv5j1201	1681	27	hemotropic	hemotropic	NNP
cord-022561-rv5j1201	1681	28	parasites	parasite	NNS
cord-022561-rv5j1201	1681	29	.	.	.
cord-022561-rv5j1201	1682	1	As	as	IN
cord-022561-rv5j1201	1682	2	a	a	DT
cord-022561-rv5j1201	1682	3	secondary	secondary	JJ
cord-022561-rv5j1201	1682	4	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	1682	5	organ	organ	NN
cord-022561-rv5j1201	1682	6	,	,	,
cord-022561-rv5j1201	1682	7	its	-PRON-	PRP$
cord-022561-rv5j1201	1682	8	immunologic	immunologic	JJ
cord-022561-rv5j1201	1682	9	functions	function	NNS
cord-022561-rv5j1201	1682	10	include	include	VBP
cord-022561-rv5j1201	1682	11	the	the	DT
cord-022561-rv5j1201	1682	12	activation	activation	NN
cord-022561-rv5j1201	1682	13	of	of	IN
cord-022561-rv5j1201	1682	14	macrophages	macrophage	NNS
cord-022561-rv5j1201	1682	15	to	to	TO
cord-022561-rv5j1201	1682	16	process	process	VB
cord-022561-rv5j1201	1682	17	and	and	CC
cord-022561-rv5j1201	1682	18	present	present	JJ
cord-022561-rv5j1201	1682	19	antigen	antigen	NN
cord-022561-rv5j1201	1682	20	,	,	,
cord-022561-rv5j1201	1682	21	the	the	DT
cord-022561-rv5j1201	1682	22	proliferation	proliferation	NN
cord-022561-rv5j1201	1682	23	of	of	IN
cord-022561-rv5j1201	1682	24	B	b	NN
cord-022561-rv5j1201	1682	25	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	1682	26	and	and	CC
cord-022561-rv5j1201	1682	27	production	production	NN
cord-022561-rv5j1201	1682	28	of	of	IN
cord-022561-rv5j1201	1682	29	antibody	antibody	NN
cord-022561-rv5j1201	1682	30	and	and	CC
cord-022561-rv5j1201	1682	31	biologic	biologic	JJ
cord-022561-rv5j1201	1682	32	molecules	molecule	NNS
cord-022561-rv5j1201	1682	33	,	,	,
cord-022561-rv5j1201	1682	34	and	and	CC
cord-022561-rv5j1201	1682	35	the	the	DT
cord-022561-rv5j1201	1682	36	interaction	interaction	NN
cord-022561-rv5j1201	1682	37	of	of	IN
cord-022561-rv5j1201	1682	38	T	t	NN
cord-022561-rv5j1201	1682	39	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	1682	40	and	and	CC
cord-022561-rv5j1201	1682	41	antigens	antigen	NNS
cord-022561-rv5j1201	1682	42	.	.	.
cord-022561-rv5j1201	1683	1	In	in	IN
cord-022561-rv5j1201	1683	2	some	some	DT
cord-022561-rv5j1201	1683	3	species	specie	NNS
cord-022561-rv5j1201	1683	4	the	the	DT
cord-022561-rv5j1201	1683	5	spleen	spleen	NN
cord-022561-rv5j1201	1683	6	stores	store	NNS
cord-022561-rv5j1201	1683	7	significant	significant	JJ
cord-022561-rv5j1201	1683	8	quantities	quantity	NNS
cord-022561-rv5j1201	1683	9	of	of	IN
cord-022561-rv5j1201	1683	10	blood	blood	NN
cord-022561-rv5j1201	1683	11	(	(	-LRB-
cord-022561-rv5j1201	1683	12	Box	Box	NNP
cord-022561-rv5j1201	1683	13	13	13	CD
cord-022561-rv5j1201	1683	14	-	-	SYM
cord-022561-rv5j1201	1683	15	7	7	CD
cord-022561-rv5j1201	1683	16	)	)	-RRB-
cord-022561-rv5j1201	1683	17	.	.	.
cord-022561-rv5j1201	1684	1	The	the	DT
cord-022561-rv5j1201	1684	2	functions	function	NNS
cord-022561-rv5j1201	1684	3	of	of	IN
cord-022561-rv5j1201	1684	4	the	the	DT
cord-022561-rv5j1201	1684	5	spleen	spleen	NNS
cord-022561-rv5j1201	1684	6	are	be	VBP
cord-022561-rv5j1201	1684	7	best	well	RBS
cord-022561-rv5j1201	1684	8	considered	consider	VBN
cord-022561-rv5j1201	1684	9	on	on	IN
cord-022561-rv5j1201	1684	10	the	the	DT
cord-022561-rv5j1201	1684	11	basis	basis	NN
cord-022561-rv5j1201	1684	12	of	of	IN
cord-022561-rv5j1201	1684	13	the	the	DT
cord-022561-rv5j1201	1684	14	two	two	CD
cord-022561-rv5j1201	1684	15	main	main	JJ
cord-022561-rv5j1201	1684	16	components	component	NNS
cord-022561-rv5j1201	1684	17	of	of	IN
cord-022561-rv5j1201	1684	18	the	the	DT
cord-022561-rv5j1201	1684	19	spleen	spleen	NN
cord-022561-rv5j1201	1684	20	:	:	:
cord-022561-rv5j1201	1684	21	the	the	DT
cord-022561-rv5j1201	1684	22	red	red	JJ
cord-022561-rv5j1201	1684	23	and	and	CC
cord-022561-rv5j1201	1684	24	white	white	JJ
cord-022561-rv5j1201	1684	25	pulp	pulp	NN
cord-022561-rv5j1201	1684	26	and	and	CC
cord-022561-rv5j1201	1684	27	the	the	DT
cord-022561-rv5j1201	1684	28	anatomic	anatomic	JJ
cord-022561-rv5j1201	1684	29	systems	system	NNS
cord-022561-rv5j1201	1684	30	contained	contain	VBN
cord-022561-rv5j1201	1684	31	within	within	IN
cord-022561-rv5j1201	1684	32	them	-PRON-	PRP
cord-022561-rv5j1201	1684	33	(	(	-LRB-
cord-022561-rv5j1201	1684	34	monocyte	monocyte	JJ
cord-022561-rv5j1201	1684	35	-	-	HYPH
cord-022561-rv5j1201	1684	36	macrophage	macrophage	NN
cord-022561-rv5j1201	1684	37	system	system	NN
cord-022561-rv5j1201	1684	38	,	,	,
cord-022561-rv5j1201	1684	39	red	red	JJ
cord-022561-rv5j1201	1684	40	pulp	pulp	NN
cord-022561-rv5j1201	1684	41	vascular	vascular	JJ
cord-022561-rv5j1201	1684	42	spaces	space	NNS
cord-022561-rv5j1201	1684	43	,	,	,
cord-022561-rv5j1201	1684	44	and	and	CC
cord-022561-rv5j1201	1684	45	hematopoiesis	hematopoiesis	NN
cord-022561-rv5j1201	1684	46	in	in	IN
cord-022561-rv5j1201	1684	47	the	the	DT
cord-022561-rv5j1201	1684	48	red	red	JJ
cord-022561-rv5j1201	1684	49	pulp	pulp	NN
cord-022561-rv5j1201	1684	50	,	,	,
cord-022561-rv5j1201	1684	51	and	and	CC
cord-022561-rv5j1201	1684	52	the	the	DT
cord-022561-rv5j1201	1684	53	B	B	NNP
cord-022561-rv5j1201	1684	54	and	and	CC
cord-022561-rv5j1201	1684	55	T	T	NNP
cord-022561-rv5j1201	1684	56	lymphocyte	lymphocyte	NN
cord-022561-rv5j1201	1684	57	systems	system	NNS
cord-022561-rv5j1201	1684	58	within	within	IN
cord-022561-rv5j1201	1684	59	the	the	DT
cord-022561-rv5j1201	1684	60	white	white	JJ
cord-022561-rv5j1201	1684	61	pulp	pulp	NN
cord-022561-rv5j1201	1684	62	)	)	-RRB-
cord-022561-rv5j1201	1684	63	.	.	.
cord-022561-rv5j1201	1685	1	Monocyte	Monocyte	NNP
cord-022561-rv5j1201	1685	2	-	-	HYPH
cord-022561-rv5j1201	1685	3	Macrophage	Macrophage	NNP
cord-022561-rv5j1201	1685	4	System	System	NNP
cord-022561-rv5j1201	1685	5	.	.	.
cord-022561-rv5j1201	1686	1	Within	within	IN
cord-022561-rv5j1201	1686	2	the	the	DT
cord-022561-rv5j1201	1686	3	red	red	JJ
cord-022561-rv5j1201	1686	4	pulp	pulp	NN
cord-022561-rv5j1201	1686	5	,	,	,
cord-022561-rv5j1201	1686	6	macrophages	macrophage	NNS
cord-022561-rv5j1201	1686	7	are	be	VBP
cord-022561-rv5j1201	1686	8	located	locate	VBN
cord-022561-rv5j1201	1686	9	in	in	IN
cord-022561-rv5j1201	1686	10	the	the	DT
cord-022561-rv5j1201	1686	11	marginal	marginal	JJ
cord-022561-rv5j1201	1686	12	sinus	sinus	NN
cord-022561-rv5j1201	1686	13	,	,	,
cord-022561-rv5j1201	1686	14	PAMS	PAMS	NNP
cord-022561-rv5j1201	1686	15	,	,	,
cord-022561-rv5j1201	1686	16	and	and	CC
cord-022561-rv5j1201	1686	17	attached	attach	VBN
cord-022561-rv5j1201	1686	18	to	to	IN
cord-022561-rv5j1201	1686	19	the	the	DT
cord-022561-rv5j1201	1686	20	reticular	reticular	JJ
cord-022561-rv5j1201	1686	21	walls	wall	NNS
cord-022561-rv5j1201	1686	22	of	of	IN
cord-022561-rv5j1201	1686	23	the	the	DT
cord-022561-rv5j1201	1686	24	red	red	JJ
cord-022561-rv5j1201	1686	25	pulp	pulp	NN
cord-022561-rv5j1201	1686	26	vascular	vascular	JJ
cord-022561-rv5j1201	1686	27	spaces	space	NNS
cord-022561-rv5j1201	1686	28	.	.	.
cord-022561-rv5j1201	1687	1	In	in	IN
cord-022561-rv5j1201	1687	2	the	the	DT
cord-022561-rv5j1201	1687	3	dog	dog	NN
cord-022561-rv5j1201	1687	4	,	,	,
cord-022561-rv5j1201	1687	5	macrophages	macrophage	NNS
cord-022561-rv5j1201	1687	6	are	be	VBP
cord-022561-rv5j1201	1687	7	also	also	RB
cord-022561-rv5j1201	1687	8	located	locate	VBN
cord-022561-rv5j1201	1687	9	perisinusoidally	perisinusoidally	RB
cord-022561-rv5j1201	1687	10	.	.	.
cord-022561-rv5j1201	1688	1	The	the	DT
cord-022561-rv5j1201	1688	2	supportive	supportive	JJ
cord-022561-rv5j1201	1688	3	reticular	reticular	JJ
cord-022561-rv5j1201	1688	4	network	network	NN
cord-022561-rv5j1201	1688	5	of	of	IN
cord-022561-rv5j1201	1688	6	the	the	DT
cord-022561-rv5j1201	1688	7	red	red	JJ
cord-022561-rv5j1201	1688	8	pulp	pulp	NN
cord-022561-rv5j1201	1688	9	vascular	vascular	JJ
cord-022561-rv5j1201	1688	10	spaces	space	NNS
cord-022561-rv5j1201	1688	11	is	be	VBZ
cord-022561-rv5j1201	1688	12	composed	compose	VBN
cord-022561-rv5j1201	1688	13	of	of	IN
cord-022561-rv5j1201	1688	14	a	a	DT
cord-022561-rv5j1201	1688	15	fine	fine	JJ
cord-022561-rv5j1201	1688	16	meshwork	meshwork	NN
cord-022561-rv5j1201	1688	17	of	of	IN
cord-022561-rv5j1201	1688	18	reticular	reticular	JJ
cord-022561-rv5j1201	1688	19	fibers	fiber	NNS
cord-022561-rv5j1201	1688	20	made	make	VBN
cord-022561-rv5j1201	1688	21	of	of	IN
cord-022561-rv5j1201	1688	22	type	type	NN
cord-022561-rv5j1201	1688	23	III	iii	CD
cord-022561-rv5j1201	1688	24	collagen	collagen	NN
cord-022561-rv5j1201	1688	25	,	,	,
cord-022561-rv5j1201	1688	26	on	on	IN
cord-022561-rv5j1201	1688	27	which	which	WDT
cord-022561-rv5j1201	1688	28	macrophages	macrophage	NNS
cord-022561-rv5j1201	1688	29	are	be	VBP
cord-022561-rv5j1201	1688	30	dispersed	disperse	VBN
cord-022561-rv5j1201	1688	31	.	.	.
cord-022561-rv5j1201	1689	1	Exactly	exactly	RB
cord-022561-rv5j1201	1689	2	in	in	IN
cord-022561-rv5j1201	1689	3	which	which	WDT
cord-022561-rv5j1201	1689	4	of	of	IN
cord-022561-rv5j1201	1689	5	these	these	DT
cord-022561-rv5j1201	1689	6	concentrations	concentration	NNS
cord-022561-rv5j1201	1689	7	of	of	IN
cord-022561-rv5j1201	1689	8	macrophages	macrophage	NNS
cord-022561-rv5j1201	1689	9	phagocytosis	phagocytosis	NN
cord-022561-rv5j1201	1689	10	of	of	IN
cord-022561-rv5j1201	1689	11	blood	blood	NN
cord-022561-rv5j1201	1689	12	-	-	HYPH
cord-022561-rv5j1201	1689	13	borne	bear	VBN
cord-022561-rv5j1201	1689	14	particles	particle	NNS
cord-022561-rv5j1201	1689	15	takes	take	VBZ
cord-022561-rv5j1201	1689	16	place	place	NN
cord-022561-rv5j1201	1689	17	depends	depend	VBZ
cord-022561-rv5j1201	1689	18	upon	upon	IN
cord-022561-rv5j1201	1689	19	(	(	-LRB-
cord-022561-rv5j1201	1689	20	1	1	LS
cord-022561-rv5j1201	1689	21	)	)	-RRB-
cord-022561-rv5j1201	1689	22	the	the	DT
cord-022561-rv5j1201	1689	23	sequence	sequence	NN
cord-022561-rv5j1201	1689	24	in	in	IN
cord-022561-rv5j1201	1689	25	which	which	WDT
cord-022561-rv5j1201	1689	26	they	-PRON-	PRP
cord-022561-rv5j1201	1689	27	are	be	VBP
cord-022561-rv5j1201	1689	28	exposed	expose	VBN
cord-022561-rv5j1201	1689	29	to	to	IN
cord-022561-rv5j1201	1689	30	the	the	DT
cord-022561-rv5j1201	1689	31	incoming	incoming	JJ
cord-022561-rv5j1201	1689	32	blood	blood	NN
cord-022561-rv5j1201	1689	33	,	,	,
cord-022561-rv5j1201	1689	34	(	(	-LRB-
cord-022561-rv5j1201	1689	35	2	2	LS
cord-022561-rv5j1201	1689	36	)	)	-RRB-
cord-022561-rv5j1201	1689	37	the	the	DT
cord-022561-rv5j1201	1689	38	concentration	concentration	NN
cord-022561-rv5j1201	1689	39	of	of	IN
cord-022561-rv5j1201	1689	40	macrophages	macrophage	NNS
cord-022561-rv5j1201	1689	41	in	in	IN
cord-022561-rv5j1201	1689	42	these	these	DT
cord-022561-rv5j1201	1689	43	areas	area	NNS
cord-022561-rv5j1201	1689	44	(	(	-LRB-
cord-022561-rv5j1201	1689	45	e.g.	e.g.	RB
cord-022561-rv5j1201	1689	46	,	,	,
cord-022561-rv5j1201	1689	47	the	the	DT
cord-022561-rv5j1201	1689	48	cat	cat	NN
cord-022561-rv5j1201	1689	49	marginal	marginal	JJ
cord-022561-rv5j1201	1689	50	sinus	sinus	NN
cord-022561-rv5j1201	1689	51	is	be	VBZ
cord-022561-rv5j1201	1689	52	small	small	JJ
cord-022561-rv5j1201	1689	53	and	and	CC
cord-022561-rv5j1201	1689	54	thus	thus	RB
cord-022561-rv5j1201	1689	55	not	not	RB
cord-022561-rv5j1201	1689	56	a	a	DT
cord-022561-rv5j1201	1689	57	major	major	JJ
cord-022561-rv5j1201	1689	58	site	site	NN
cord-022561-rv5j1201	1689	59	of	of	IN
cord-022561-rv5j1201	1689	60	clearance	clearance	NN
cord-022561-rv5j1201	1689	61	;	;	:
cord-022561-rv5j1201	1689	62	there	there	EX
cord-022561-rv5j1201	1689	63	is	be	VBZ
cord-022561-rv5j1201	1689	64	a	a	DT
cord-022561-rv5j1201	1689	65	compensatory	compensatory	JJ
cord-022561-rv5j1201	1689	66	increase	increase	NN
cord-022561-rv5j1201	1689	67	in	in	IN
cord-022561-rv5j1201	1689	68	PAMS	PAMS	NNP
cord-022561-rv5j1201	1689	69	for	for	IN
cord-022561-rv5j1201	1689	70	phagocytosis	phagocytosis	NN
cord-022561-rv5j1201	1689	71	)	)	-RRB-
cord-022561-rv5j1201	1689	72	,	,	,
cord-022561-rv5j1201	1689	73	and	and	CC
cord-022561-rv5j1201	1689	74	(	(	-LRB-
cord-022561-rv5j1201	1689	75	3	3	LS
cord-022561-rv5j1201	1689	76	)	)	-RRB-
cord-022561-rv5j1201	1689	77	the	the	DT
cord-022561-rv5j1201	1689	78	functions	function	NNS
cord-022561-rv5j1201	1689	79	of	of	IN
cord-022561-rv5j1201	1689	80	the	the	DT
cord-022561-rv5j1201	1689	81	macrophages	macrophage	NNS
cord-022561-rv5j1201	1689	82	.	.	.
cord-022561-rv5j1201	1690	1	Some	some	DT
cord-022561-rv5j1201	1690	2	of	of	IN
cord-022561-rv5j1201	1690	3	the	the	DT
cord-022561-rv5j1201	1690	4	macrophages	macrophage	NNS
cord-022561-rv5j1201	1690	5	in	in	IN
cord-022561-rv5j1201	1690	6	the	the	DT
cord-022561-rv5j1201	1690	7	marginal	marginal	JJ
cord-022561-rv5j1201	1690	8	sinus	sinus	NN
cord-022561-rv5j1201	1690	9	and	and	CC
cord-022561-rv5j1201	1690	10	marginal	marginal	JJ
cord-022561-rv5j1201	1690	11	zone	zone	NN
cord-022561-rv5j1201	1690	12	are	be	VBP
cord-022561-rv5j1201	1690	13	responsible	responsible	JJ
cord-022561-rv5j1201	1690	14	for	for	IN
cord-022561-rv5j1201	1690	15	phagocytosis	phagocytosis	NN
cord-022561-rv5j1201	1690	16	of	of	IN
cord-022561-rv5j1201	1690	17	particulate	particulate	NN
cord-022561-rv5j1201	1690	18	matter	matter	NN
cord-022561-rv5j1201	1690	19	and	and	CC
cord-022561-rv5j1201	1690	20	others	other	NNS
cord-022561-rv5j1201	1690	21	for	for	IN
cord-022561-rv5j1201	1690	22	the	the	DT
cord-022561-rv5j1201	1690	23	trapping	trapping	NN
cord-022561-rv5j1201	1690	24	and	and	CC
cord-022561-rv5j1201	1690	25	ingestion	ingestion	NN
cord-022561-rv5j1201	1690	26	of	of	IN
cord-022561-rv5j1201	1690	27	antigens	antigen	NNS
cord-022561-rv5j1201	1690	28	and	and	CC
cord-022561-rv5j1201	1690	29	antigen	antigen	NN
cord-022561-rv5j1201	1690	30	-	-	HYPH
cord-022561-rv5j1201	1690	31	antibody	antibody	NN
cord-022561-rv5j1201	1690	32	complexes	complex	NNS
cord-022561-rv5j1201	1690	33	.	.	.
cord-022561-rv5j1201	1691	1	Macrophages	macrophage	NNS
cord-022561-rv5j1201	1691	2	responsible	responsible	JJ
cord-022561-rv5j1201	1691	3	for	for	IN
cord-022561-rv5j1201	1691	4	phagocytosis	phagocytosis	NN
cord-022561-rv5j1201	1691	5	of	of	IN
cord-022561-rv5j1201	1691	6	blood	blood	NN
cord-022561-rv5j1201	1691	7	-	-	HYPH
cord-022561-rv5j1201	1691	8	borne	bear	VBN
cord-022561-rv5j1201	1691	9	foreign	foreign	JJ
cord-022561-rv5j1201	1691	10	material	material	NN
cord-022561-rv5j1201	1692	1	(	(	-LRB-
cord-022561-rv5j1201	1692	2	Fig	Fig	NNP
cord-022561-rv5j1201	1692	3	.	.	NNP
cord-022561-rv5j1201	1692	4	13	13	CD
cord-022561-rv5j1201	1692	5	-	-	SYM
cord-022561-rv5j1201	1692	6	44	44	CD
cord-022561-rv5j1201	1692	7	)	)	-RRB-
cord-022561-rv5j1201	1692	8	,	,	,
cord-022561-rv5j1201	1692	9	bacteria	bacteria	NNS
cord-022561-rv5j1201	1692	10	,	,	,
cord-022561-rv5j1201	1692	11	and	and	CC
cord-022561-rv5j1201	1692	12	senescent	senescent	JJ
cord-022561-rv5j1201	1692	13	and/or	and/or	CC
cord-022561-rv5j1201	1692	14	damaged	damaged	JJ
cord-022561-rv5j1201	1692	15	erythrocytes	erythrocyte	NNS
cord-022561-rv5j1201	1692	16	(	(	-LRB-
cord-022561-rv5j1201	1693	1	e.g.	e.g.	RB
cord-022561-rv5j1201	1693	2	,	,	,
cord-022561-rv5j1201	1693	3	as	as	IN
cord-022561-rv5j1201	1693	4	seen	see	VBN
cord-022561-rv5j1201	1693	5	in	in	IN
cord-022561-rv5j1201	1693	6	immune	immune	NN
cord-022561-rv5j1201	1693	7	-	-	HYPH
cord-022561-rv5j1201	1693	8	mediated	mediate	VBN
cord-022561-rv5j1201	1693	9	anemias	anemia	NNS
cord-022561-rv5j1201	1693	10	and	and	CC
cord-022561-rv5j1201	1693	11	infections	infection	NNS
cord-022561-rv5j1201	1693	12	with	with	IN
cord-022561-rv5j1201	1693	13	hemotropic	hemotropic	NNP
cord-022561-rv5j1201	1693	14	parasites	parasite	NNS
cord-022561-rv5j1201	1693	15	)	)	-RRB-
cord-022561-rv5j1201	1693	16	are	be	VBP
cord-022561-rv5j1201	1693	17	also	also	RB
cord-022561-rv5j1201	1693	18	found	find	VBN
cord-022561-rv5j1201	1693	19	in	in	IN
cord-022561-rv5j1201	1693	20	the	the	DT
cord-022561-rv5j1201	1693	21	red	red	JJ
cord-022561-rv5j1201	1693	22	pulp	pulp	NN
cord-022561-rv5j1201	1693	23	.	.	.
cord-022561-rv5j1201	1694	1	In	in	IN
cord-022561-rv5j1201	1694	2	the	the	DT
cord-022561-rv5j1201	1694	3	dog	dog	NN
cord-022561-rv5j1201	1694	4	,	,	,
cord-022561-rv5j1201	1694	5	sinusoidal	sinusoidal	JJ
cord-022561-rv5j1201	1694	6	macrophages	macrophage	NNS
cord-022561-rv5j1201	1694	7	remove	remove	VBP
cord-022561-rv5j1201	1694	8	entire	entire	JJ
cord-022561-rv5j1201	1694	9	erythrocytes	erythrocyte	NNS
cord-022561-rv5j1201	1694	10	(	(	-LRB-
cord-022561-rv5j1201	1694	11	erythrophagocytosis	erythrophagocytosis	NNP
cord-022561-rv5j1201	1694	12	)	)	-RRB-
cord-022561-rv5j1201	1694	13	,	,	,
cord-022561-rv5j1201	1694	14	as	as	RB
cord-022561-rv5j1201	1694	15	well	well	RB
cord-022561-rv5j1201	1694	16	as	as	IN
cord-022561-rv5j1201	1694	17	portions	portion	NNS
cord-022561-rv5j1201	1694	18	of	of	IN
cord-022561-rv5j1201	1694	19	an	an	DT
cord-022561-rv5j1201	1694	20	erythrocyte	erythrocyte	NN
cord-022561-rv5j1201	1694	21	's	's	POS
cord-022561-rv5j1201	1694	22	membrane	membrane	NN
cord-022561-rv5j1201	1694	23	and	and	CC
cord-022561-rv5j1201	1694	24	cytoplasmic	cytoplasmic	JJ
cord-022561-rv5j1201	1694	25	inclusions	inclusion	NNS
cord-022561-rv5j1201	1694	26	,	,	,
cord-022561-rv5j1201	1694	27	such	such	JJ
cord-022561-rv5j1201	1694	28	as	as	IN
cord-022561-rv5j1201	1694	29	nuclear	nuclear	JJ
cord-022561-rv5j1201	1694	30	remnants	remnant	NNS
cord-022561-rv5j1201	1694	31	like	like	IN
cord-022561-rv5j1201	1694	32	Heinz	Heinz	NNP
cord-022561-rv5j1201	1694	33	bodies	body	NNS
cord-022561-rv5j1201	1694	34	,	,	,
cord-022561-rv5j1201	1694	35	by	by	IN
cord-022561-rv5j1201	1694	36	a	a	DT
cord-022561-rv5j1201	1694	37	process	process	NN
cord-022561-rv5j1201	1694	38	called	call	VBN
cord-022561-rv5j1201	1694	39	pitting	pit	VBG
cord-022561-rv5j1201	1694	40	.	.	.
cord-022561-rv5j1201	1695	1	As	as	IN
cord-022561-rv5j1201	1695	2	such	such	JJ
cord-022561-rv5j1201	1695	3	,	,	,
cord-022561-rv5j1201	1695	4	the	the	DT
cord-022561-rv5j1201	1695	5	presence	presence	NN
cord-022561-rv5j1201	1695	6	of	of	IN
cord-022561-rv5j1201	1695	7	large	large	JJ
cord-022561-rv5j1201	1695	8	numbers	number	NNS
cord-022561-rv5j1201	1695	9	of	of	IN
cord-022561-rv5j1201	1695	10	nuclear	nuclear	JJ
cord-022561-rv5j1201	1695	11	remnants	remnant	NNS
cord-022561-rv5j1201	1695	12	in	in	IN
cord-022561-rv5j1201	1695	13	erythrocytes	erythrocyte	NNS
cord-022561-rv5j1201	1695	14	in	in	IN
cord-022561-rv5j1201	1695	15	canine	canine	JJ
cord-022561-rv5j1201	1695	16	blood	blood	NN
cord-022561-rv5j1201	1695	17	smears	smear	NNS
cord-022561-rv5j1201	1695	18	may	may	MD
cord-022561-rv5j1201	1695	19	indicate	indicate	VB
cord-022561-rv5j1201	1695	20	malfunction	malfunction	NN
cord-022561-rv5j1201	1695	21	of	of	IN
cord-022561-rv5j1201	1695	22	the	the	DT
cord-022561-rv5j1201	1695	23	sinusoidal	sinusoidal	JJ
cord-022561-rv5j1201	1695	24	system	system	NN
cord-022561-rv5j1201	1695	25	.	.	.
cord-022561-rv5j1201	1696	1	The	the	DT
cord-022561-rv5j1201	1696	2	normal	normal	JJ
cord-022561-rv5j1201	1696	3	rate	rate	NN
cord-022561-rv5j1201	1696	4	of	of	IN
cord-022561-rv5j1201	1696	5	removal	removal	NN
cord-022561-rv5j1201	1696	6	of	of	IN
cord-022561-rv5j1201	1696	7	senescent	senescent	JJ
cord-022561-rv5j1201	1696	8	erythrocytes	erythrocyte	NNS
cord-022561-rv5j1201	1696	9	from	from	IN
cord-022561-rv5j1201	1696	10	the	the	DT
cord-022561-rv5j1201	1696	11	circulating	circulate	VBG
cord-022561-rv5j1201	1696	12	blood	blood	NN
cord-022561-rv5j1201	1696	13	does	do	VBZ
cord-022561-rv5j1201	1696	14	not	not	RB
cord-022561-rv5j1201	1696	15	cause	cause	VB
cord-022561-rv5j1201	1696	16	an	an	DT
cord-022561-rv5j1201	1696	17	increase	increase	NN
cord-022561-rv5j1201	1696	18	in	in	IN
cord-022561-rv5j1201	1696	19	size	size	NN
cord-022561-rv5j1201	1696	20	of	of	IN
cord-022561-rv5j1201	1696	21	the	the	DT
cord-022561-rv5j1201	1696	22	spleen	spleen	NN
cord-022561-rv5j1201	1696	23	;	;	:
cord-022561-rv5j1201	1696	24	however	however	RB
cord-022561-rv5j1201	1696	25	,	,	,
cord-022561-rv5j1201	1696	26	splenomegaly	splenomegaly	NN
cord-022561-rv5j1201	1696	27	can	can	MD
cord-022561-rv5j1201	1696	28	be	be	VB
cord-022561-rv5j1201	1696	29	observed	observe	VBN
cord-022561-rv5j1201	1696	30	when	when	WRB
cord-022561-rv5j1201	1696	31	large	large	JJ
cord-022561-rv5j1201	1696	32	numbers	number	NNS
cord-022561-rv5j1201	1696	33	of	of	IN
cord-022561-rv5j1201	1696	34	defective	defective	JJ
cord-022561-rv5j1201	1696	35	erythrocytes	erythrocyte	NNS
cord-022561-rv5j1201	1696	36	must	must	MD
cord-022561-rv5j1201	1696	37	be	be	VB
cord-022561-rv5j1201	1696	38	removed	remove	VBN
cord-022561-rv5j1201	1696	39	,	,	,
cord-022561-rv5j1201	1696	40	as	as	IN
cord-022561-rv5j1201	1696	41	in	in	IN
cord-022561-rv5j1201	1696	42	cases	case	NNS
cord-022561-rv5j1201	1696	43	of	of	IN
cord-022561-rv5j1201	1696	44	severe	severe	JJ
cord-022561-rv5j1201	1696	45	acute	acute	JJ
cord-022561-rv5j1201	1696	46	hemolytic	hemolytic	JJ
cord-022561-rv5j1201	1696	47	anemia	anemia	NN
cord-022561-rv5j1201	1696	48	.	.	.
cord-022561-rv5j1201	1697	1	Nonsinusoidal	nonsinusoidal	JJ
cord-022561-rv5j1201	1697	2	spleens	spleen	NNS
cord-022561-rv5j1201	1697	3	lack	lack	VBP
cord-022561-rv5j1201	1697	4	the	the	DT
cord-022561-rv5j1201	1697	5	fenestrated	fenestrated	JJ
cord-022561-rv5j1201	1697	6	endothelium	endothelium	NN
cord-022561-rv5j1201	1697	7	and	and	CC
cord-022561-rv5j1201	1697	8	perisinusoidal	perisinusoidal	JJ
cord-022561-rv5j1201	1697	9	macrophages	macrophage	NNS
cord-022561-rv5j1201	1697	10	of	of	IN
cord-022561-rv5j1201	1697	11	canine	canine	JJ
cord-022561-rv5j1201	1697	12	sinusoids	sinusoid	NNS
cord-022561-rv5j1201	1697	13	that	that	WDT
cord-022561-rv5j1201	1697	14	allow	allow	VBP
cord-022561-rv5j1201	1697	15	for	for	IN
cord-022561-rv5j1201	1697	16	slow	slow	JJ
cord-022561-rv5j1201	1697	17	processing	processing	NN
cord-022561-rv5j1201	1697	18	of	of	IN
cord-022561-rv5j1201	1697	19	red	red	JJ
cord-022561-rv5j1201	1697	20	blood	blood	NN
cord-022561-rv5j1201	1697	21	cells	cell	NNS
cord-022561-rv5j1201	1697	22	to	to	TO
cord-022561-rv5j1201	1697	23	determine	determine	VB
cord-022561-rv5j1201	1697	24	which	which	WDT
cord-022561-rv5j1201	1697	25	are	be	VBP
cord-022561-rv5j1201	1697	26	to	to	TO
cord-022561-rv5j1201	1697	27	be	be	VB
cord-022561-rv5j1201	1697	28	returned	return	VBN
cord-022561-rv5j1201	1697	29	to	to	IN
cord-022561-rv5j1201	1697	30	the	the	DT
cord-022561-rv5j1201	1697	31	Equine	equine	JJ
cord-022561-rv5j1201	1697	32	,	,	,
cord-022561-rv5j1201	1697	33	canine	canine	JJ
cord-022561-rv5j1201	1697	34	,	,	,
cord-022561-rv5j1201	1697	35	and	and	CC
cord-022561-rv5j1201	1697	36	feline	feline	JJ
cord-022561-rv5j1201	1697	37	spleens	spleen	NNS
cord-022561-rv5j1201	1697	38	all	all	DT
cord-022561-rv5j1201	1697	39	have	have	VBP
cord-022561-rv5j1201	1697	40	considerable	considerable	JJ
cord-022561-rv5j1201	1697	41	storage	storage	NN
cord-022561-rv5j1201	1697	42	and	and	CC
cord-022561-rv5j1201	1697	43	contractile	contractile	NN
cord-022561-rv5j1201	1697	44	capacity	capacity	NN
cord-022561-rv5j1201	1697	45	because	because	IN
cord-022561-rv5j1201	1697	46	of	of	IN
cord-022561-rv5j1201	1697	47	their	-PRON-	PRP$
cord-022561-rv5j1201	1697	48	muscular	muscular	JJ
cord-022561-rv5j1201	1697	49	capsule	capsule	NN
cord-022561-rv5j1201	1697	50	,	,	,
cord-022561-rv5j1201	1697	51	increased	increase	VBN
cord-022561-rv5j1201	1697	52	numbers	number	NNS
cord-022561-rv5j1201	1697	53	of	of	IN
cord-022561-rv5j1201	1697	54	trabeculae	trabeculae	NNP
cord-022561-rv5j1201	1697	55	,	,	,
cord-022561-rv5j1201	1697	56	and	and	CC
cord-022561-rv5j1201	1697	57	the	the	DT
cord-022561-rv5j1201	1697	58	relatively	relatively	RB
cord-022561-rv5j1201	1697	59	small	small	JJ
cord-022561-rv5j1201	1697	60	amount	amount	NN
cord-022561-rv5j1201	1697	61	of	of	IN
cord-022561-rv5j1201	1697	62	splenic	splenic	JJ
cord-022561-rv5j1201	1697	63	parenchyma	parenchyma	NNS
cord-022561-rv5j1201	1697	64	devoted	devote	VBN
cord-022561-rv5j1201	1697	65	to	to	IN
cord-022561-rv5j1201	1697	66	white	white	JJ
cord-022561-rv5j1201	1697	67	pulp	pulp	NN
cord-022561-rv5j1201	1697	68	.	.	.
cord-022561-rv5j1201	1698	1	The	the	DT
cord-022561-rv5j1201	1698	2	storage	storage	NN
cord-022561-rv5j1201	1698	3	capacity	capacity	NN
cord-022561-rv5j1201	1698	4	in	in	IN
cord-022561-rv5j1201	1698	5	dogs	dog	NNS
cord-022561-rv5j1201	1698	6	and	and	CC
cord-022561-rv5j1201	1698	7	horses	horse	NNS
cord-022561-rv5j1201	1698	8	is	be	VBZ
cord-022561-rv5j1201	1698	9	remarkable	remarkable	JJ
cord-022561-rv5j1201	1698	10	:	:	:
cord-022561-rv5j1201	1698	11	It	-PRON-	PRP
cord-022561-rv5j1201	1698	12	has	have	VBZ
cord-022561-rv5j1201	1698	13	been	be	VBN
cord-022561-rv5j1201	1698	14	claimed	claim	VBN
cord-022561-rv5j1201	1698	15	that	that	IN
cord-022561-rv5j1201	1698	16	the	the	DT
cord-022561-rv5j1201	1698	17	canine	canine	JJ
cord-022561-rv5j1201	1698	18	spleen	spleen	NNS
cord-022561-rv5j1201	1698	19	can	can	MD
cord-022561-rv5j1201	1698	20	store	store	VB
cord-022561-rv5j1201	1698	21	one	one	CD
cord-022561-rv5j1201	1698	22	-	-	HYPH
cord-022561-rv5j1201	1698	23	third	third	NN
cord-022561-rv5j1201	1698	24	of	of	IN
cord-022561-rv5j1201	1698	25	the	the	DT
cord-022561-rv5j1201	1698	26	dog	dog	NN
cord-022561-rv5j1201	1698	27	's	's	POS
cord-022561-rv5j1201	1698	28	erythrocytes	erythrocyte	NNS
cord-022561-rv5j1201	1698	29	while	while	IN
cord-022561-rv5j1201	1698	30	the	the	DT
cord-022561-rv5j1201	1698	31	animal	animal	NN
cord-022561-rv5j1201	1698	32	sleeps	sleep	VBZ
cord-022561-rv5j1201	1698	33	and	and	CC
cord-022561-rv5j1201	1698	34	the	the	DT
cord-022561-rv5j1201	1698	35	equine	equine	JJ
cord-022561-rv5j1201	1698	36	spleen	spleen	NN
cord-022561-rv5j1201	1698	37	holds	hold	VBZ
cord-022561-rv5j1201	1698	38	one	one	CD
cord-022561-rv5j1201	1698	39	-	-	HYPH
cord-022561-rv5j1201	1698	40	half	half	NN
cord-022561-rv5j1201	1698	41	of	of	IN
cord-022561-rv5j1201	1698	42	the	the	DT
cord-022561-rv5j1201	1698	43	animal	animal	NN
cord-022561-rv5j1201	1698	44	's	's	POS
cord-022561-rv5j1201	1698	45	circulating	circulate	VBG
cord-022561-rv5j1201	1698	46	red	red	JJ
cord-022561-rv5j1201	1698	47	cell	cell	NN
cord-022561-rv5j1201	1698	48	mass	mass	NN
cord-022561-rv5j1201	1698	49	(	(	-LRB-
cord-022561-rv5j1201	1698	50	which	which	WDT
cord-022561-rv5j1201	1698	51	is	be	VBZ
cord-022561-rv5j1201	1698	52	considered	consider	VBN
cord-022561-rv5j1201	1698	53	advantageous	advantageous	JJ
cord-022561-rv5j1201	1698	54	because	because	IN
cord-022561-rv5j1201	1698	55	it	-PRON-	PRP
cord-022561-rv5j1201	1698	56	reduces	reduce	VBZ
cord-022561-rv5j1201	1698	57	the	the	DT
cord-022561-rv5j1201	1698	58	viscosity	viscosity	NN
cord-022561-rv5j1201	1698	59	of	of	IN
cord-022561-rv5j1201	1698	60	the	the	DT
cord-022561-rv5j1201	1698	61	circulating	circulate	VBG
cord-022561-rv5j1201	1698	62	blood	blood	NN
cord-022561-rv5j1201	1698	63	)	)	-RRB-
cord-022561-rv5j1201	1698	64	.	.	.
cord-022561-rv5j1201	1699	1	Storage	storage	NN
cord-022561-rv5j1201	1699	2	spleens	spleen	NNS
cord-022561-rv5j1201	1699	3	expand	expand	VBP
cord-022561-rv5j1201	1699	4	and	and	CC
cord-022561-rv5j1201	1699	5	contract	contract	VB
cord-022561-rv5j1201	1699	6	quickly	quickly	RB
cord-022561-rv5j1201	1699	7	under	under	IN
cord-022561-rv5j1201	1699	8	the	the	DT
cord-022561-rv5j1201	1699	9	influence	influence	NN
cord-022561-rv5j1201	1699	10	of	of	IN
cord-022561-rv5j1201	1699	11	the	the	DT
cord-022561-rv5j1201	1699	12	autonomic	autonomic	JJ
cord-022561-rv5j1201	1699	13	nervous	nervous	JJ
cord-022561-rv5j1201	1699	14	system	system	NN
cord-022561-rv5j1201	1699	15	,	,	,
cord-022561-rv5j1201	1699	16	via	via	IN
cord-022561-rv5j1201	1699	17	sympathetic	sympathetic	JJ
cord-022561-rv5j1201	1699	18	and	and	CC
cord-022561-rv5j1201	1699	19	vagal	vagal	JJ
cord-022561-rv5j1201	1699	20	fibers	fiber	NNS
cord-022561-rv5j1201	1699	21	in	in	IN
cord-022561-rv5j1201	1699	22	the	the	DT
cord-022561-rv5j1201	1699	23	trabeculae	trabeculae	NNP
cord-022561-rv5j1201	1699	24	and	and	CC
cord-022561-rv5j1201	1699	25	reticular	reticular	JJ
cord-022561-rv5j1201	1699	26	walls	wall	NNS
cord-022561-rv5j1201	1699	27	of	of	IN
cord-022561-rv5j1201	1699	28	the	the	DT
cord-022561-rv5j1201	1699	29	red	red	JJ
cord-022561-rv5j1201	1699	30	pulp	pulp	NN
cord-022561-rv5j1201	1699	31	vascular	vascular	JJ
cord-022561-rv5j1201	1699	32	spaces	space	NNS
cord-022561-rv5j1201	1699	33	and	and	CC
cord-022561-rv5j1201	1699	34	other	other	JJ
cord-022561-rv5j1201	1699	35	circulatory	circulatory	JJ
cord-022561-rv5j1201	1699	36	disruptions	disruption	NNS
cord-022561-rv5j1201	1699	37	,	,	,
cord-022561-rv5j1201	1699	38	such	such	JJ
cord-022561-rv5j1201	1699	39	as	as	IN
cord-022561-rv5j1201	1699	40	hypovolemic	hypovolemic	JJ
cord-022561-rv5j1201	1699	41	and/or	and/or	CC
cord-022561-rv5j1201	1699	42	cardiogenic	cardiogenic	JJ
cord-022561-rv5j1201	1699	43	shock	shock	NN
cord-022561-rv5j1201	1699	44	.	.	.
cord-022561-rv5j1201	1700	1	Thus	thus	RB
cord-022561-rv5j1201	1700	2	storage	storage	NN
cord-022561-rv5j1201	1700	3	spleens	spleen	NNS
cord-022561-rv5j1201	1700	4	may	may	MD
cord-022561-rv5j1201	1700	5	be	be	VB
cord-022561-rv5j1201	1700	6	either	either	CC
cord-022561-rv5j1201	1700	7	grossly	grossly	RB
cord-022561-rv5j1201	1700	8	enlarged	enlarge	VBN
cord-022561-rv5j1201	1700	9	and	and	CC
cord-022561-rv5j1201	1700	10	congested	congested	JJ
cord-022561-rv5j1201	1700	11	or	or	CC
cord-022561-rv5j1201	1700	12	small	small	JJ
cord-022561-rv5j1201	1700	13	with	with	IN
cord-022561-rv5j1201	1700	14	a	a	DT
cord-022561-rv5j1201	1700	15	wrinkled	wrinkled	JJ
cord-022561-rv5j1201	1700	16	surface	surface	NN
cord-022561-rv5j1201	1700	17	and	and	CC
cord-022561-rv5j1201	1700	18	a	a	DT
cord-022561-rv5j1201	1700	19	dry	dry	JJ
cord-022561-rv5j1201	1700	20	parenchyma	parenchyma	NN
cord-022561-rv5j1201	1700	21	depending	depend	VBG
cord-022561-rv5j1201	1700	22	on	on	IN
cord-022561-rv5j1201	1700	23	whether	whether	IN
cord-022561-rv5j1201	1700	24	the	the	DT
cord-022561-rv5j1201	1700	25	spleen	spleen	NN
cord-022561-rv5j1201	1700	26	is	be	VBZ
cord-022561-rv5j1201	1700	27	congested	congest	VBN
cord-022561-rv5j1201	1700	28	from	from	IN
cord-022561-rv5j1201	1700	29	stored	store	VBN
cord-022561-rv5j1201	1700	30	blood	blood	NN
cord-022561-rv5j1201	1700	31	or	or	CC
cord-022561-rv5j1201	1700	32	shrunken	shrink	VBN
cord-022561-rv5j1201	1700	33	from	from	IN
cord-022561-rv5j1201	1700	34	contraction	contraction	NN
cord-022561-rv5j1201	1700	35	(	(	-LRB-
cord-022561-rv5j1201	1700	36	see	see	VB
cord-022561-rv5j1201	1700	37	Uniform	Uniform	NNP
cord-022561-rv5j1201	1700	38	Splenomegaly	Splenomegaly	NNP
cord-022561-rv5j1201	1700	39	and	and	CC
cord-022561-rv5j1201	1700	40	Small	Small	NNP
cord-022561-rv5j1201	1700	41	Spleens	spleen	NNS
cord-022561-rv5j1201	1700	42	)	)	-RRB-
cord-022561-rv5j1201	1700	43	.	.	.
cord-022561-rv5j1201	1701	1	Hematopoietic	Hematopoietic	NNP
cord-022561-rv5j1201	1701	2	Tissue	Tissue	NNP
cord-022561-rv5j1201	1701	3	.	.	.
cord-022561-rv5j1201	1702	1	In	in	IN
cord-022561-rv5j1201	1702	2	the	the	DT
cord-022561-rv5j1201	1702	3	developing	develop	VBG
cord-022561-rv5j1201	1702	4	fetus	fetus	NN
cord-022561-rv5j1201	1702	5	the	the	DT
cord-022561-rv5j1201	1702	6	liver	liver	NN
cord-022561-rv5j1201	1702	7	is	be	VBZ
cord-022561-rv5j1201	1702	8	the	the	DT
cord-022561-rv5j1201	1702	9	primary	primary	JJ
cord-022561-rv5j1201	1702	10	site	site	NN
cord-022561-rv5j1201	1702	11	of	of	IN
cord-022561-rv5j1201	1702	12	hematopoiesis	hematopoiesis	NN
cord-022561-rv5j1201	1702	13	,	,	,
cord-022561-rv5j1201	1702	14	with	with	IN
cord-022561-rv5j1201	1702	15	the	the	DT
cord-022561-rv5j1201	1702	16	spleen	spleen	NN
cord-022561-rv5j1201	1702	17	making	make	VBG
cord-022561-rv5j1201	1702	18	a	a	DT
cord-022561-rv5j1201	1702	19	minor	minor	JJ
cord-022561-rv5j1201	1702	20	contribution	contribution	NN
cord-022561-rv5j1201	1702	21	.	.	.
cord-022561-rv5j1201	1703	1	Shortly	shortly	RB
cord-022561-rv5j1201	1703	2	before	before	IN
cord-022561-rv5j1201	1703	3	or	or	CC
cord-022561-rv5j1201	1703	4	after	after	IN
cord-022561-rv5j1201	1703	5	birth	birth	NN
cord-022561-rv5j1201	1703	6	,	,	,
cord-022561-rv5j1201	1703	7	hematopoiesis	hematopoiesis	NN
cord-022561-rv5j1201	1703	8	ceases	cease	VBZ
cord-022561-rv5j1201	1703	9	in	in	IN
cord-022561-rv5j1201	1703	10	the	the	DT
cord-022561-rv5j1201	1703	11	liver	liver	NN
cord-022561-rv5j1201	1703	12	and	and	CC
cord-022561-rv5j1201	1703	13	spleen	spleen	NNS
cord-022561-rv5j1201	1703	14	,	,	,
cord-022561-rv5j1201	1703	15	and	and	CC
cord-022561-rv5j1201	1703	16	the	the	DT
cord-022561-rv5j1201	1703	17	bone	bone	NN
cord-022561-rv5j1201	1703	18	marrow	marrow	NN
cord-022561-rv5j1201	1703	19	becomes	become	VBZ
cord-022561-rv5j1201	1703	20	the	the	DT
cord-022561-rv5j1201	1703	21	primary	primary	JJ
cord-022561-rv5j1201	1703	22	hematopoietic	hematopoietic	JJ
cord-022561-rv5j1201	1703	23	organ	organ	NN
cord-022561-rv5j1201	1703	24	.	.	.
cord-022561-rv5j1201	1704	1	Under	under	IN
cord-022561-rv5j1201	1704	2	certain	certain	JJ
cord-022561-rv5j1201	1704	3	conditions	condition	NNS
cord-022561-rv5j1201	1704	4	,	,	,
cord-022561-rv5j1201	1704	5	such	such	JJ
cord-022561-rv5j1201	1704	6	as	as	IN
cord-022561-rv5j1201	1704	7	severe	severe	JJ
cord-022561-rv5j1201	1704	8	demand	demand	NN
cord-022561-rv5j1201	1704	9	due	due	JJ
cord-022561-rv5j1201	1704	10	to	to	IN
cord-022561-rv5j1201	1704	11	prolonged	prolonged	JJ
cord-022561-rv5j1201	1704	12	anemia	anemia	NN
cord-022561-rv5j1201	1704	13	,	,	,
cord-022561-rv5j1201	1704	14	splenic	splenic	JJ
cord-022561-rv5j1201	1704	15	hematopoiesis	hematopoiesis	NN
cord-022561-rv5j1201	1704	16	can	can	MD
cord-022561-rv5j1201	1704	17	be	be	VB
cord-022561-rv5j1201	1704	18	reactivated	reactivate	VBN
cord-022561-rv5j1201	1704	19	;	;	:
cord-022561-rv5j1201	1704	20	this	this	DT
cord-022561-rv5j1201	1704	21	outcome	outcome	NN
cord-022561-rv5j1201	1704	22	is	be	VBZ
cord-022561-rv5j1201	1704	23	called	call	VBN
cord-022561-rv5j1201	1704	24	extramedullary	extramedullary	NNP
cord-022561-rv5j1201	1704	25	hematopoiesis	hematopoiesis	NNP
cord-022561-rv5j1201	1704	26	(	(	-LRB-
cord-022561-rv5j1201	1704	27	EMH	EMH	NNP
cord-022561-rv5j1201	1704	28	)	)	-RRB-
cord-022561-rv5j1201	1704	29	.	.	.
cord-022561-rv5j1201	1705	1	Studies	study	NNS
cord-022561-rv5j1201	1705	2	have	have	VBP
cord-022561-rv5j1201	1705	3	indicated	indicate	VBN
cord-022561-rv5j1201	1705	4	that	that	IN
cord-022561-rv5j1201	1705	5	splenic	splenic	JJ
cord-022561-rv5j1201	1705	6	EMH	EMH	NNP
cord-022561-rv5j1201	1705	7	in	in	IN
cord-022561-rv5j1201	1705	8	dogs	dog	NNS
cord-022561-rv5j1201	1705	9	and	and	CC
cord-022561-rv5j1201	1705	10	cats	cat	NNS
cord-022561-rv5j1201	1705	11	most	most	RBS
cord-022561-rv5j1201	1705	12	commonly	commonly	RB
cord-022561-rv5j1201	1705	13	occurs	occur	VBZ
cord-022561-rv5j1201	1705	14	with	with	IN
cord-022561-rv5j1201	1705	15	degenerative	degenerative	JJ
cord-022561-rv5j1201	1705	16	or	or	CC
cord-022561-rv5j1201	1705	17	inflammatory	inflammatory	JJ
cord-022561-rv5j1201	1705	18	circulation	circulation	NN
cord-022561-rv5j1201	1705	19	,	,	,
cord-022561-rv5j1201	1705	20	pitted	pit	VBN
cord-022561-rv5j1201	1705	21	,	,	,
cord-022561-rv5j1201	1705	22	or	or	CC
cord-022561-rv5j1201	1705	23	phagocytized	phagocytize	VBN
cord-022561-rv5j1201	1705	24	.	.	.
cord-022561-rv5j1201	1706	1	Instead	instead	RB
cord-022561-rv5j1201	1706	2	,	,	,
cord-022561-rv5j1201	1706	3	the	the	DT
cord-022561-rv5j1201	1706	4	macrophages	macrophage	NNS
cord-022561-rv5j1201	1706	5	of	of	IN
cord-022561-rv5j1201	1706	6	the	the	DT
cord-022561-rv5j1201	1706	7	red	red	JJ
cord-022561-rv5j1201	1706	8	pulp	pulp	NN
cord-022561-rv5j1201	1706	9	perform	perform	VBP
cord-022561-rv5j1201	1706	10	these	these	DT
cord-022561-rv5j1201	1706	11	functions	function	NNS
cord-022561-rv5j1201	1706	12	,	,	,
cord-022561-rv5j1201	1706	13	and	and	CC
cord-022561-rv5j1201	1706	14	phagocytized	phagocytized	JJ
cord-022561-rv5j1201	1706	15	cells	cell	NNS
cord-022561-rv5j1201	1706	16	remain	remain	VBP
cord-022561-rv5j1201	1706	17	in	in	IN
cord-022561-rv5j1201	1706	18	the	the	DT
cord-022561-rv5j1201	1706	19	red	red	JJ
cord-022561-rv5j1201	1706	20	pulp	pulp	NN
cord-022561-rv5j1201	1706	21	vascular	vascular	JJ
cord-022561-rv5j1201	1706	22	spaces	space	NNS
cord-022561-rv5j1201	1706	23	.	.	.
cord-022561-rv5j1201	1707	1	The	the	DT
cord-022561-rv5j1201	1707	2	location	location	NN
cord-022561-rv5j1201	1707	3	of	of	IN
cord-022561-rv5j1201	1707	4	the	the	DT
cord-022561-rv5j1201	1707	5	primary	primary	JJ
cord-022561-rv5j1201	1707	6	sites	site	NNS
cord-022561-rv5j1201	1707	7	of	of	IN
cord-022561-rv5j1201	1707	8	pitting	pit	VBG
cord-022561-rv5j1201	1707	9	in	in	IN
cord-022561-rv5j1201	1707	10	nonsinusoidal	nonsinusoidal	JJ
cord-022561-rv5j1201	1707	11	spleens	spleen	NNS
cord-022561-rv5j1201	1707	12	is	be	VBZ
cord-022561-rv5j1201	1707	13	unclear	unclear	JJ
cord-022561-rv5j1201	1707	14	,	,	,
cord-022561-rv5j1201	1707	15	but	but	CC
cord-022561-rv5j1201	1707	16	it	-PRON-	PRP
cord-022561-rv5j1201	1707	17	is	be	VBZ
cord-022561-rv5j1201	1707	18	likely	likely	JJ
cord-022561-rv5j1201	1707	19	that	that	IN
cord-022561-rv5j1201	1707	20	most	most	JJS
cord-022561-rv5j1201	1707	21	erythrophagocytosis	erythrophagocytosis	NN
cord-022561-rv5j1201	1707	22	takes	take	VBZ
cord-022561-rv5j1201	1707	23	place	place	NN
cord-022561-rv5j1201	1707	24	in	in	IN
cord-022561-rv5j1201	1707	25	the	the	DT
cord-022561-rv5j1201	1707	26	red	red	JJ
cord-022561-rv5j1201	1707	27	pulp	pulp	NN
cord-022561-rv5j1201	1707	28	vascular	vascular	JJ
cord-022561-rv5j1201	1707	29	spaces	space	NNS
cord-022561-rv5j1201	1707	30	.	.	.
cord-022561-rv5j1201	1708	1	The	the	DT
cord-022561-rv5j1201	1708	2	cat	cat	NN
cord-022561-rv5j1201	1708	3	's	's	POS
cord-022561-rv5j1201	1708	4	spleen	spleen	NN
cord-022561-rv5j1201	1708	5	is	be	VBZ
cord-022561-rv5j1201	1708	6	deficient	deficient	JJ
cord-022561-rv5j1201	1708	7	in	in	IN
cord-022561-rv5j1201	1708	8	pitting	pit	VBG
cord-022561-rv5j1201	1708	9	,	,	,
cord-022561-rv5j1201	1708	10	and	and	CC
cord-022561-rv5j1201	1708	11	removal	removal	NN
cord-022561-rv5j1201	1708	12	of	of	IN
cord-022561-rv5j1201	1708	13	Heinz	Heinz	NNP
cord-022561-rv5j1201	1708	14	bodies	body	NNS
cord-022561-rv5j1201	1708	15	is	be	VBZ
cord-022561-rv5j1201	1708	16	slow	slow	JJ
cord-022561-rv5j1201	1708	17	;	;	:
cord-022561-rv5j1201	1708	18	however	however	RB
cord-022561-rv5j1201	1708	19	,	,	,
cord-022561-rv5j1201	1708	20	some	some	DT
cord-022561-rv5j1201	1708	21	erythrophagocytosis	erythrophagocytosis	NN
cord-022561-rv5j1201	1708	22	does	do	VBZ
cord-022561-rv5j1201	1708	23	occur	occur	VB
cord-022561-rv5j1201	1708	24	in	in	IN
cord-022561-rv5j1201	1708	25	the	the	DT
cord-022561-rv5j1201	1708	26	marginal	marginal	JJ
cord-022561-rv5j1201	1708	27	sinus	sinus	NN
cord-022561-rv5j1201	1708	28	.	.	.
cord-022561-rv5j1201	1709	1	The	the	DT
cord-022561-rv5j1201	1709	2	macrophages	macrophage	NNS
cord-022561-rv5j1201	1709	3	of	of	IN
cord-022561-rv5j1201	1709	4	the	the	DT
cord-022561-rv5j1201	1709	5	sinusoids	sinusoid	NNS
cord-022561-rv5j1201	1709	6	,	,	,
cord-022561-rv5j1201	1709	7	marginal	marginal	JJ
cord-022561-rv5j1201	1709	8	sinus	sinus	NN
cord-022561-rv5j1201	1709	9	,	,	,
cord-022561-rv5j1201	1709	10	and	and	CC
cord-022561-rv5j1201	1709	11	red	red	JJ
cord-022561-rv5j1201	1709	12	pulp	pulp	NN
cord-022561-rv5j1201	1709	13	vascular	vascular	JJ
cord-022561-rv5j1201	1709	14	spaces	space	NNS
cord-022561-rv5j1201	1709	15	are	be	VBP
cord-022561-rv5j1201	1709	16	of	of	IN
cord-022561-rv5j1201	1709	17	bone	bone	NN
cord-022561-rv5j1201	1709	18	marrow	marrow	NN
cord-022561-rv5j1201	1709	19	origin	origin	NN
cord-022561-rv5j1201	1709	20	.	.	.
cord-022561-rv5j1201	1710	1	From	from	IN
cord-022561-rv5j1201	1710	2	the	the	DT
cord-022561-rv5j1201	1710	3	bone	bone	NN
cord-022561-rv5j1201	1710	4	marrow	marrow	NN
cord-022561-rv5j1201	1710	5	these	these	DT
cord-022561-rv5j1201	1710	6	cells	cell	NNS
cord-022561-rv5j1201	1710	7	circulate	circulate	VBP
cord-022561-rv5j1201	1710	8	in	in	IN
cord-022561-rv5j1201	1710	9	the	the	DT
cord-022561-rv5j1201	1710	10	blood	blood	NN
cord-022561-rv5j1201	1710	11	as	as	IN
cord-022561-rv5j1201	1710	12	monocytes	monocyte	NNS
cord-022561-rv5j1201	1710	13	and	and	CC
cord-022561-rv5j1201	1710	14	migrate	migrate	VB
cord-022561-rv5j1201	1710	15	into	into	IN
cord-022561-rv5j1201	1710	16	the	the	DT
cord-022561-rv5j1201	1710	17	spleen	spleen	NN
cord-022561-rv5j1201	1710	18	.	.	.
cord-022561-rv5j1201	1711	1	Some	some	DT
cord-022561-rv5j1201	1711	2	macrophages	macrophage	NNS
cord-022561-rv5j1201	1711	3	are	be	VBP
cord-022561-rv5j1201	1711	4	replenished	replenish	VBN
cord-022561-rv5j1201	1711	5	by	by	IN
cord-022561-rv5j1201	1711	6	local	local	JJ
cord-022561-rv5j1201	1711	7	proliferation	proliferation	NN
cord-022561-rv5j1201	1711	8	.	.	.
cord-022561-rv5j1201	1712	1	For	for	IN
cord-022561-rv5j1201	1712	2	example	example	NN
cord-022561-rv5j1201	1712	3	,	,	,
cord-022561-rv5j1201	1712	4	after	after	IN
cord-022561-rv5j1201	1712	5	phagocytizing	phagocytize	VBG
cord-022561-rv5j1201	1712	6	large	large	JJ
cord-022561-rv5j1201	1712	7	amounts	amount	NNS
cord-022561-rv5j1201	1712	8	of	of	IN
cord-022561-rv5j1201	1712	9	material	material	NN
cord-022561-rv5j1201	1712	10	from	from	IN
cord-022561-rv5j1201	1712	11	the	the	DT
cord-022561-rv5j1201	1712	12	blood	blood	NN
cord-022561-rv5j1201	1712	13	,	,	,
cord-022561-rv5j1201	1712	14	the	the	DT
cord-022561-rv5j1201	1712	15	macrophages	macrophage	NNS
cord-022561-rv5j1201	1712	16	of	of	IN
cord-022561-rv5j1201	1712	17	the	the	DT
cord-022561-rv5j1201	1712	18	PAMS	PAMS	NNP
cord-022561-rv5j1201	1712	19	migrate	migrate	VBP
cord-022561-rv5j1201	1712	20	through	through	IN
cord-022561-rv5j1201	1712	21	the	the	DT
cord-022561-rv5j1201	1712	22	wall	wall	NN
cord-022561-rv5j1201	1712	23	of	of	IN
cord-022561-rv5j1201	1712	24	the	the	DT
cord-022561-rv5j1201	1712	25	cuff	cuff	NN
cord-022561-rv5j1201	1712	26	into	into	IN
cord-022561-rv5j1201	1712	27	the	the	DT
cord-022561-rv5j1201	1712	28	adjacent	adjacent	JJ
cord-022561-rv5j1201	1712	29	red	red	JJ
cord-022561-rv5j1201	1712	30	pulp	pulp	NN
cord-022561-rv5j1201	1712	31	,	,	,
cord-022561-rv5j1201	1712	32	denuding	denude	VBG
cord-022561-rv5j1201	1712	33	the	the	DT
cord-022561-rv5j1201	1712	34	PAMS	PAMS	NNP
cord-022561-rv5j1201	1712	35	of	of	IN
cord-022561-rv5j1201	1712	36	macrophages	macrophage	NNS
cord-022561-rv5j1201	1712	37	.	.	.
cord-022561-rv5j1201	1713	1	After	after	IN
cord-022561-rv5j1201	1713	2	24	24	CD
cord-022561-rv5j1201	1713	3	hours	hour	NNS
cord-022561-rv5j1201	1713	4	,	,	,
cord-022561-rv5j1201	1713	5	local	local	JJ
cord-022561-rv5j1201	1713	6	residual	residual	JJ
cord-022561-rv5j1201	1713	7	macrophages	macrophage	NNS
cord-022561-rv5j1201	1713	8	have	have	VBP
cord-022561-rv5j1201	1713	9	proliferated	proliferate	VBN
cord-022561-rv5j1201	1713	10	to	to	TO
cord-022561-rv5j1201	1713	11	repopulate	repopulate	VB
cord-022561-rv5j1201	1713	12	the	the	DT
cord-022561-rv5j1201	1713	13	PAMS	PAMS	NNP
cord-022561-rv5j1201	1713	14	.	.	.
cord-022561-rv5j1201	1714	1	The	the	DT
cord-022561-rv5j1201	1714	2	fixed	fix	VBN
cord-022561-rv5j1201	1714	3	macrophages	macrophage	NNS
cord-022561-rv5j1201	1714	4	elsewhere	elsewhere	RB
cord-022561-rv5j1201	1714	5	in	in	IN
cord-022561-rv5j1201	1714	6	the	the	DT
cord-022561-rv5j1201	1714	7	body	body	NN
cord-022561-rv5j1201	1714	8	,	,	,
cord-022561-rv5j1201	1714	9	namely	namely	RB
cord-022561-rv5j1201	1714	10	,	,	,
cord-022561-rv5j1201	1714	11	those	those	DT
cord-022561-rv5j1201	1714	12	in	in	IN
cord-022561-rv5j1201	1714	13	connective	connective	JJ
cord-022561-rv5j1201	1714	14	tissue	tissue	NN
cord-022561-rv5j1201	1714	15	,	,	,
cord-022561-rv5j1201	1714	16	lymph	lymph	NN
cord-022561-rv5j1201	1714	17	nodes	node	NNS
cord-022561-rv5j1201	1714	18	(	(	-LRB-
cord-022561-rv5j1201	1714	19	sinus	sinus	NNP
cord-022561-rv5j1201	1714	20	histiocytes	histiocytes	NNPS
cord-022561-rv5j1201	1714	21	)	)	-RRB-
cord-022561-rv5j1201	1714	22	,	,	,
cord-022561-rv5j1201	1714	23	liver	liver	NN
cord-022561-rv5j1201	1714	24	(	(	-LRB-
cord-022561-rv5j1201	1714	25	Kupffer	Kupffer	NNP
cord-022561-rv5j1201	1714	26	cells	cell	NNS
cord-022561-rv5j1201	1714	27	)	)	-RRB-
cord-022561-rv5j1201	1714	28	,	,	,
cord-022561-rv5j1201	1714	29	lung	lung	NN
cord-022561-rv5j1201	1714	30	(	(	-LRB-
cord-022561-rv5j1201	1714	31	pulmonary	pulmonary	JJ
cord-022561-rv5j1201	1714	32	intravascular	intravascular	JJ
cord-022561-rv5j1201	1714	33	macrophages	macrophage	NNS
cord-022561-rv5j1201	1714	34	and	and	CC
cord-022561-rv5j1201	1714	35	pulmonary	pulmonary	JJ
cord-022561-rv5j1201	1714	36	alveolar	alveolar	NN
cord-022561-rv5j1201	1714	37	macrophages	macrophage	NNS
cord-022561-rv5j1201	1714	38	)	)	-RRB-
cord-022561-rv5j1201	1714	39	,	,	,
cord-022561-rv5j1201	1714	40	and	and	CC
cord-022561-rv5j1201	1714	41	brain	brain	NN
cord-022561-rv5j1201	1714	42	(	(	-LRB-
cord-022561-rv5j1201	1714	43	resident	resident	JJ
cord-022561-rv5j1201	1714	44	and	and	CC
cord-022561-rv5j1201	1714	45	perivascular	perivascular	JJ
cord-022561-rv5j1201	1714	46	microglial	microglial	JJ
cord-022561-rv5j1201	1714	47	cells	cell	NNS
cord-022561-rv5j1201	1714	48	)	)	-RRB-
cord-022561-rv5j1201	1714	49	,	,	,
cord-022561-rv5j1201	1714	50	are	be	VBP
cord-022561-rv5j1201	1714	51	also	also	RB
cord-022561-rv5j1201	1714	52	derived	derive	VBN
cord-022561-rv5j1201	1714	53	from	from	IN
cord-022561-rv5j1201	1714	54	bone	bone	NN
cord-022561-rv5j1201	1714	55	marrow	marrow	NN
cord-022561-rv5j1201	1714	56	(	(	-LRB-
cord-022561-rv5j1201	1714	57	see	see	VB
cord-022561-rv5j1201	1714	58	Chapters	chapter	NNS
cord-022561-rv5j1201	1714	59	5	5	CD
cord-022561-rv5j1201	1714	60	,	,	,
cord-022561-rv5j1201	1714	61	8	8	CD
cord-022561-rv5j1201	1714	62	,	,	,
cord-022561-rv5j1201	1714	63	9	9	CD
cord-022561-rv5j1201	1714	64	,	,	,
cord-022561-rv5j1201	1714	65	and	and	CC
cord-022561-rv5j1201	1714	66	14	14	CD
cord-022561-rv5j1201	1714	67	)	)	-RRB-
cord-022561-rv5j1201	1714	68	.	.	.
cord-022561-rv5j1201	1715	1	Storage	storage	NN
cord-022561-rv5j1201	1715	2	or	or	CC
cord-022561-rv5j1201	1715	3	Defense	Defense	NNP
cord-022561-rv5j1201	1715	4	Spleens	spleen	NNS
cord-022561-rv5j1201	1715	5	.	.	.
cord-022561-rv5j1201	1716	1	Spleens	spleen	NNS
cord-022561-rv5j1201	1716	2	are	be	VBP
cord-022561-rv5j1201	1716	3	also	also	RB
cord-022561-rv5j1201	1716	4	classified	classify	VBN
cord-022561-rv5j1201	1716	5	as	as	IN
cord-022561-rv5j1201	1716	6	either	either	DT
cord-022561-rv5j1201	1716	7	storage	storage	NN
cord-022561-rv5j1201	1716	8	or	or	CC
cord-022561-rv5j1201	1716	9	defense	defense	NN
cord-022561-rv5j1201	1716	10	spleens	spleen	NNS
cord-022561-rv5j1201	1716	11	,	,	,
cord-022561-rv5j1201	1716	12	based	base	VBN
cord-022561-rv5j1201	1716	13	on	on	IN
cord-022561-rv5j1201	1716	14	whether	whether	IN
cord-022561-rv5j1201	1716	15	or	or	CC
cord-022561-rv5j1201	1716	16	not	not	RB
cord-022561-rv5j1201	1716	17	they	-PRON-	PRP
cord-022561-rv5j1201	1716	18	can	can	MD
cord-022561-rv5j1201	1716	19	store	store	VB
cord-022561-rv5j1201	1716	20	significant	significant	JJ
cord-022561-rv5j1201	1716	21	volumes	volume	NNS
cord-022561-rv5j1201	1716	22	of	of	IN
cord-022561-rv5j1201	1716	23	blood	blood	NN
cord-022561-rv5j1201	1716	24	.	.	.
cord-022561-rv5j1201	1717	1	The	the	DT
cord-022561-rv5j1201	1717	2	ability	ability	NN
cord-022561-rv5j1201	1717	3	to	to	TO
cord-022561-rv5j1201	1717	4	store	store	VB
cord-022561-rv5j1201	1717	5	blood	blood	NN
cord-022561-rv5j1201	1717	6	in	in	IN
cord-022561-rv5j1201	1717	7	the	the	DT
cord-022561-rv5j1201	1717	8	spleen	spleen	NN
cord-022561-rv5j1201	1717	9	depends	depend	VBZ
cord-022561-rv5j1201	1717	10	on	on	IN
cord-022561-rv5j1201	1717	11	the	the	DT
cord-022561-rv5j1201	1717	12	fibromuscular	fibromuscular	JJ
cord-022561-rv5j1201	1717	13	composition	composition	NN
cord-022561-rv5j1201	1717	14	of	of	IN
cord-022561-rv5j1201	1717	15	the	the	DT
cord-022561-rv5j1201	1717	16	splenic	splenic	JJ
cord-022561-rv5j1201	1717	17	capsule	capsule	NN
cord-022561-rv5j1201	1717	18	and	and	CC
cord-022561-rv5j1201	1717	19	trabeculae	trabeculae	NNP
cord-022561-rv5j1201	1717	20	.	.	.
cord-022561-rv5j1201	1718	1	Splenic	splenic	JJ
cord-022561-rv5j1201	1718	2	capsules	capsule	NNS
cord-022561-rv5j1201	1718	3	and	and	CC
cord-022561-rv5j1201	1718	4	trabeculae	trabecula	NNS
cord-022561-rv5j1201	1718	5	with	with	IN
cord-022561-rv5j1201	1718	6	a	a	DT
cord-022561-rv5j1201	1718	7	low	low	JJ
cord-022561-rv5j1201	1718	8	percentage	percentage	NN
cord-022561-rv5j1201	1718	9	of	of	IN
cord-022561-rv5j1201	1718	10	smooth	smooth	JJ
cord-022561-rv5j1201	1718	11	muscle	muscle	NN
cord-022561-rv5j1201	1718	12	and	and	CC
cord-022561-rv5j1201	1718	13	elastic	elastic	JJ
cord-022561-rv5j1201	1718	14	fibers	fiber	NNS
cord-022561-rv5j1201	1718	15	can	can	MD
cord-022561-rv5j1201	1718	16	not	not	RB
cord-022561-rv5j1201	1718	17	expand	expand	VB
cord-022561-rv5j1201	1718	18	and	and	CC
cord-022561-rv5j1201	1718	19	contract	contract	VB
cord-022561-rv5j1201	1718	20	and	and	CC
cord-022561-rv5j1201	1718	21	are	be	VBP
cord-022561-rv5j1201	1718	22	designated	designate	VBN
cord-022561-rv5j1201	1718	23	as	as	IN
cord-022561-rv5j1201	1718	24	defense	defense	NN
cord-022561-rv5j1201	1718	25	spleens	spleen	NNS
cord-022561-rv5j1201	1718	26	.	.	.
cord-022561-rv5j1201	1719	1	These	these	DT
cord-022561-rv5j1201	1719	2	are	be	VBP
cord-022561-rv5j1201	1719	3	found	find	VBN
cord-022561-rv5j1201	1719	4	in	in	IN
cord-022561-rv5j1201	1719	5	rabbits	rabbit	NNS
cord-022561-rv5j1201	1719	6	and	and	CC
cord-022561-rv5j1201	1719	7	human	human	JJ
cord-022561-rv5j1201	1719	8	beings	being	NNS
cord-022561-rv5j1201	1719	9	.	.	.
cord-022561-rv5j1201	1720	1	The	the	DT
cord-022561-rv5j1201	1720	2	spleens	spleen	NNS
cord-022561-rv5j1201	1720	3	of	of	IN
cord-022561-rv5j1201	1720	4	other	other	JJ
cord-022561-rv5j1201	1720	5	domestic	domestic	JJ
cord-022561-rv5j1201	1720	6	animal	animal	NN
cord-022561-rv5j1201	1720	7	species	specie	NNS
cord-022561-rv5j1201	1720	8	have	have	VBP
cord-022561-rv5j1201	1720	9	distention	distention	NN
cord-022561-rv5j1201	1720	10	of	of	IN
cord-022561-rv5j1201	1720	11	the	the	DT
cord-022561-rv5j1201	1720	12	red	red	JJ
cord-022561-rv5j1201	1720	13	pulp	pulp	NN
cord-022561-rv5j1201	1720	14	from	from	IN
cord-022561-rv5j1201	1720	15	stored	store	VBN
cord-022561-rv5j1201	1720	16	blood	blood	NN
cord-022561-rv5j1201	1720	17	separates	separate	VBZ
cord-022561-rv5j1201	1720	18	the	the	DT
cord-022561-rv5j1201	1720	19	foci	foci	NN
cord-022561-rv5j1201	1720	20	of	of	IN
cord-022561-rv5j1201	1720	21	white	white	JJ
cord-022561-rv5j1201	1720	22	pulp	pulp	NN
cord-022561-rv5j1201	1720	23	(	(	-LRB-
cord-022561-rv5j1201	1720	24	PALS	pals	NN
cord-022561-rv5j1201	1720	25	and	and	CC
cord-022561-rv5j1201	1720	26	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	1720	27	follicles	follicle	NNS
cord-022561-rv5j1201	1720	28	)	)	-RRB-
cord-022561-rv5j1201	1720	29	,	,	,
cord-022561-rv5j1201	1720	30	making	make	VBG
cord-022561-rv5j1201	1720	31	white	white	JJ
cord-022561-rv5j1201	1720	32	pulp	pulp	NN
cord-022561-rv5j1201	1720	33	appear	appear	VBP
cord-022561-rv5j1201	1720	34	sparser	sparse	JJR
cord-022561-rv5j1201	1720	35	.	.	.
cord-022561-rv5j1201	1721	1	Splenic	splenic	JJ
cord-022561-rv5j1201	1721	2	white	white	JJ
cord-022561-rv5j1201	1721	3	pulp	pulp	NN
cord-022561-rv5j1201	1721	4	is	be	VBZ
cord-022561-rv5j1201	1721	5	organized	organize	VBN
cord-022561-rv5j1201	1721	6	around	around	IN
cord-022561-rv5j1201	1721	7	central	central	JJ
cord-022561-rv5j1201	1721	8	arteries	artery	NNS
cord-022561-rv5j1201	1721	9	in	in	IN
cord-022561-rv5j1201	1721	10	the	the	DT
cord-022561-rv5j1201	1721	11	form	form	NN
cord-022561-rv5j1201	1721	12	of	of	IN
cord-022561-rv5j1201	1721	13	PALS	pals	NN
cord-022561-rv5j1201	1721	14	,	,	,
cord-022561-rv5j1201	1721	15	which	which	WDT
cord-022561-rv5j1201	1721	16	are	be	VBP
cord-022561-rv5j1201	1721	17	populated	populate	VBN
cord-022561-rv5j1201	1721	18	primarily	primarily	RB
cord-022561-rv5j1201	1721	19	by	by	IN
cord-022561-rv5j1201	1721	20	T	t	NN
cord-022561-rv5j1201	1721	21	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	1721	22	(	(	-LRB-
cord-022561-rv5j1201	1721	23	see	see	VB
cord-022561-rv5j1201	1721	24	.	.	.
cord-022561-rv5j1201	1722	1	Primary	primary	JJ
cord-022561-rv5j1201	1722	2	splenic	splenic	JJ
cord-022561-rv5j1201	1722	3	follicles	follicle	NNS
cord-022561-rv5j1201	1722	4	are	be	VBP
cord-022561-rv5j1201	1722	5	located	locate	VBN
cord-022561-rv5j1201	1722	6	eccentrically	eccentrically	RB
cord-022561-rv5j1201	1722	7	in	in	IN
cord-022561-rv5j1201	1722	8	PALS	pals	NN
cord-022561-rv5j1201	1722	9	and	and	CC
cord-022561-rv5j1201	1722	10	are	be	VBP
cord-022561-rv5j1201	1722	11	primarily	primarily	RB
cord-022561-rv5j1201	1722	12	composed	compose	VBN
cord-022561-rv5j1201	1722	13	of	of	IN
cord-022561-rv5j1201	1722	14	B	b	NN
cord-022561-rv5j1201	1722	15	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	1722	16	.	.	.
cord-022561-rv5j1201	1723	1	When	when	WRB
cord-022561-rv5j1201	1723	2	exposed	expose	VBN
cord-022561-rv5j1201	1723	3	to	to	IN
cord-022561-rv5j1201	1723	4	antigen	antigen	NN
cord-022561-rv5j1201	1723	5	,	,	,
cord-022561-rv5j1201	1723	6	the	the	DT
cord-022561-rv5j1201	1723	7	splenic	splenic	JJ
cord-022561-rv5j1201	1723	8	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	1723	9	follicles	follicle	NNS
cord-022561-rv5j1201	1723	10	develop	develop	VBP
cord-022561-rv5j1201	1723	11	germinal	germinal	JJ
cord-022561-rv5j1201	1723	12	centers	center	NNS
cord-022561-rv5j1201	1723	13	(	(	-LRB-
cord-022561-rv5j1201	1723	14	see	see	VB
cord-022561-rv5j1201	1723	15	Lymphoid/	Lymphoid/	NNP
cord-022561-rv5j1201	1723	16	Lymphatic	Lymphatic	NNP
cord-022561-rv5j1201	1723	17	System	System	NNP
cord-022561-rv5j1201	1723	18	,	,	,
cord-022561-rv5j1201	1723	19	Lymph	lymph	NN
cord-022561-rv5j1201	1723	20	Nodes	node	NNS
cord-022561-rv5j1201	1723	21	,	,	,
cord-022561-rv5j1201	1723	22	Function	function	NN
cord-022561-rv5j1201	1723	23	)	)	-RRB-
cord-022561-rv5j1201	1723	24	.	.	.
cord-022561-rv5j1201	1724	1	Macrophages	macrophage	NNS
cord-022561-rv5j1201	1724	2	in	in	IN
cord-022561-rv5j1201	1724	3	the	the	DT
cord-022561-rv5j1201	1724	4	white	white	JJ
cord-022561-rv5j1201	1724	5	pulp	pulp	NN
cord-022561-rv5j1201	1724	6	follicles	follicle	NNS
cord-022561-rv5j1201	1724	7	remove	remove	VBP
cord-022561-rv5j1201	1724	8	apoptotic	apoptotic	JJ
cord-022561-rv5j1201	1724	9	B	b	NN
cord-022561-rv5j1201	1724	10	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	1724	11	not	not	RB
cord-022561-rv5j1201	1724	12	selected	select	VBN
cord-022561-rv5j1201	1724	13	for	for	IN
cord-022561-rv5j1201	1724	14	expansion	expansion	NN
cord-022561-rv5j1201	1724	15	because	because	IN
cord-022561-rv5j1201	1724	16	of	of	IN
cord-022561-rv5j1201	1724	17	low	low	JJ
cord-022561-rv5j1201	1724	18	binding	binding	NN
cord-022561-rv5j1201	1724	19	affinity	affinity	NN
cord-022561-rv5j1201	1724	20	for	for	IN
cord-022561-rv5j1201	1724	21	antigen	antigen	NN
cord-022561-rv5j1201	1724	22	.	.	.
cord-022561-rv5j1201	1725	1	Failure	failure	NN
cord-022561-rv5j1201	1725	2	of	of	IN
cord-022561-rv5j1201	1725	3	these	these	DT
cord-022561-rv5j1201	1725	4	macrophages	macrophage	NNS
cord-022561-rv5j1201	1725	5	to	to	IN
cord-022561-rv5j1201	1725	6	phagocytize	phagocytize	NNP
cord-022561-rv5j1201	1725	7	has	have	VBZ
cord-022561-rv5j1201	1725	8	been	be	VBN
cord-022561-rv5j1201	1725	9	experimentally	experimentally	RB
cord-022561-rv5j1201	1725	10	correlated	correlate	VBN
cord-022561-rv5j1201	1725	11	with	with	IN
cord-022561-rv5j1201	1725	12	decreased	decrease	VBN
cord-022561-rv5j1201	1725	13	production	production	NN
cord-022561-rv5j1201	1725	14	of	of	IN
cord-022561-rv5j1201	1725	15	growth	growth	NN
cord-022561-rv5j1201	1725	16	factors	factor	NNS
cord-022561-rv5j1201	1725	17	like	like	IN
cord-022561-rv5j1201	1725	18	TGF	TGF	NNP
cord-022561-rv5j1201	1725	19	-	-	HYPH
cord-022561-rv5j1201	1725	20	β	β	NN
cord-022561-rv5j1201	1725	21	and	and	CC
cord-022561-rv5j1201	1725	22	increased	increase	VBN
cord-022561-rv5j1201	1725	23	production	production	NN
cord-022561-rv5j1201	1725	24	of	of	IN
cord-022561-rv5j1201	1725	25	inflammatory	inflammatory	JJ
cord-022561-rv5j1201	1725	26	cytokines	cytokine	NNS
cord-022561-rv5j1201	1725	27	that	that	WDT
cord-022561-rv5j1201	1725	28	predispose	predispose	VBP
cord-022561-rv5j1201	1725	29	the	the	DT
cord-022561-rv5j1201	1725	30	animal	animal	NN
cord-022561-rv5j1201	1725	31	to	to	IN
cord-022561-rv5j1201	1725	32	autoimmune	autoimmune	JJ
cord-022561-rv5j1201	1725	33	conditions	condition	NNS
cord-022561-rv5j1201	1725	34	.	.	.
cord-022561-rv5j1201	1726	1	The	the	DT
cord-022561-rv5j1201	1726	2	marginal	marginal	JJ
cord-022561-rv5j1201	1726	3	zone	zone	NN
cord-022561-rv5j1201	1726	4	surrounds	surround	VBZ
cord-022561-rv5j1201	1726	5	the	the	DT
cord-022561-rv5j1201	1726	6	marginal	marginal	JJ
cord-022561-rv5j1201	1726	7	sinus	sinus	NN
cord-022561-rv5j1201	1726	8	at	at	IN
cord-022561-rv5j1201	1726	9	the	the	DT
cord-022561-rv5j1201	1726	10	interface	interface	NN
cord-022561-rv5j1201	1726	11	of	of	IN
cord-022561-rv5j1201	1726	12	the	the	DT
cord-022561-rv5j1201	1726	13	white	white	JJ
cord-022561-rv5j1201	1726	14	and	and	CC
cord-022561-rv5j1201	1726	15	red	red	JJ
cord-022561-rv5j1201	1726	16	pulp	pulp	NN
cord-022561-rv5j1201	1726	17	and	and	CC
cord-022561-rv5j1201	1726	18	consists	consist	VBZ
cord-022561-rv5j1201	1726	19	of	of	IN
cord-022561-rv5j1201	1726	20	macrophages	macrophage	NNS
cord-022561-rv5j1201	1726	21	,	,	,
cord-022561-rv5j1201	1726	22	DCs	DCs	NNP
cord-022561-rv5j1201	1726	23	,	,	,
cord-022561-rv5j1201	1726	24	and	and	CC
cord-022561-rv5j1201	1726	25	T	T	NNP
cord-022561-rv5j1201	1726	26	and	and	CC
cord-022561-rv5j1201	1726	27	B	b	NN
cord-022561-rv5j1201	1726	28	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	1726	29	.	.	.
cord-022561-rv5j1201	1727	1	The	the	DT
cord-022561-rv5j1201	1727	2	blood	blood	NN
cord-022561-rv5j1201	1727	3	supply	supply	NN
cord-022561-rv5j1201	1727	4	of	of	IN
cord-022561-rv5j1201	1727	5	the	the	DT
cord-022561-rv5j1201	1727	6	marginal	marginal	JJ
cord-022561-rv5j1201	1727	7	sinus	sinus	NN
cord-022561-rv5j1201	1727	8	is	be	VBZ
cord-022561-rv5j1201	1727	9	from	from	IN
cord-022561-rv5j1201	1727	10	conditions	condition	NNS
cord-022561-rv5j1201	1727	11	(	(	-LRB-
cord-022561-rv5j1201	1727	12	e.g.	e.g.	RB
cord-022561-rv5j1201	1727	13	,	,	,
cord-022561-rv5j1201	1727	14	hematomas	hematoma	NNS
cord-022561-rv5j1201	1727	15	,	,	,
cord-022561-rv5j1201	1727	16	thrombosis	thrombosis	NN
cord-022561-rv5j1201	1727	17	)	)	-RRB-
cord-022561-rv5j1201	1727	18	and	and	CC
cord-022561-rv5j1201	1727	19	may	may	MD
cord-022561-rv5j1201	1727	20	occur	occur	VB
cord-022561-rv5j1201	1727	21	without	without	IN
cord-022561-rv5j1201	1727	22	concomitant	concomitant	JJ
cord-022561-rv5j1201	1727	23	hematologic	hematologic	JJ
cord-022561-rv5j1201	1727	24	disease	disease	NN
cord-022561-rv5j1201	1727	25	(	(	-LRB-
cord-022561-rv5j1201	1727	26	see	see	VB
cord-022561-rv5j1201	1727	27	Uniform	Uniform	NNP
cord-022561-rv5j1201	1727	28	Splenomegaly	Splenomegaly	NNP
cord-022561-rv5j1201	1727	29	with	with	IN
cord-022561-rv5j1201	1727	30	a	a	DT
cord-022561-rv5j1201	1727	31	Firm	Firm	NNP
cord-022561-rv5j1201	1727	32	Consistency	Consistency	NNP
cord-022561-rv5j1201	1727	33	)	)	-RRB-
cord-022561-rv5j1201	1727	34	.	.	.
cord-022561-rv5j1201	1728	1	It	-PRON-	PRP
cord-022561-rv5j1201	1728	2	is	be	VBZ
cord-022561-rv5j1201	1728	3	also	also	RB
cord-022561-rv5j1201	1728	4	found	find	VBN
cord-022561-rv5j1201	1728	5	in	in	IN
cord-022561-rv5j1201	1728	6	splenic	splenic	JJ
cord-022561-rv5j1201	1728	7	nodular	nodular	JJ
cord-022561-rv5j1201	1728	8	hyperplasia	hyperplasia	NN
cord-022561-rv5j1201	1728	9	(	(	-LRB-
cord-022561-rv5j1201	1728	10	see	see	VB
cord-022561-rv5j1201	1728	11	Splenic	Splenic	NNP
cord-022561-rv5j1201	1728	12	Nodules	Nodules	NNPS
cord-022561-rv5j1201	1728	13	with	with	IN
cord-022561-rv5j1201	1728	14	a	a	DT
cord-022561-rv5j1201	1728	15	Firm	Firm	NNP
cord-022561-rv5j1201	1728	16	Consistency	Consistency	NNP
cord-022561-rv5j1201	1728	17	)	)	-RRB-
cord-022561-rv5j1201	1728	18	.	.	.
cord-022561-rv5j1201	1729	1	In	in	IN
cord-022561-rv5j1201	1729	2	some	some	DT
cord-022561-rv5j1201	1729	3	species	specie	NNS
cord-022561-rv5j1201	1729	4	,	,	,
cord-022561-rv5j1201	1729	5	such	such	JJ
cord-022561-rv5j1201	1729	6	as	as	IN
cord-022561-rv5j1201	1729	7	the	the	DT
cord-022561-rv5j1201	1729	8	mouse	mouse	NN
cord-022561-rv5j1201	1729	9	,	,	,
cord-022561-rv5j1201	1729	10	EMH	EMH	NNP
cord-022561-rv5j1201	1729	11	is	be	VBZ
cord-022561-rv5j1201	1729	12	a	a	DT
cord-022561-rv5j1201	1729	13	normal	normal	JJ
cord-022561-rv5j1201	1729	14	function	function	NN
cord-022561-rv5j1201	1729	15	of	of	IN
cord-022561-rv5j1201	1729	16	the	the	DT
cord-022561-rv5j1201	1729	17	adult	adult	NN
cord-022561-rv5j1201	1729	18	spleen	spleen	NNS
cord-022561-rv5j1201	1729	19	and	and	CC
cord-022561-rv5j1201	1729	20	not	not	RB
cord-022561-rv5j1201	1729	21	necessarily	necessarily	RB
cord-022561-rv5j1201	1729	22	a	a	DT
cord-022561-rv5j1201	1729	23	response	response	NN
cord-022561-rv5j1201	1729	24	to	to	IN
cord-022561-rv5j1201	1729	25	disease	disease	NN
cord-022561-rv5j1201	1729	26	or	or	CC
cord-022561-rv5j1201	1729	27	hypoxic	hypoxic	JJ
cord-022561-rv5j1201	1729	28	challenge	challenge	NN
cord-022561-rv5j1201	1729	29	.	.	.
cord-022561-rv5j1201	1730	1	The	the	DT
cord-022561-rv5j1201	1730	2	splenic	splenic	JJ
cord-022561-rv5j1201	1730	3	red	red	JJ
cord-022561-rv5j1201	1730	4	pulp	pulp	NN
cord-022561-rv5j1201	1730	5	also	also	RB
cord-022561-rv5j1201	1730	6	contains	contain	VBZ
cord-022561-rv5j1201	1730	7	large	large	JJ
cord-022561-rv5j1201	1730	8	numbers	number	NNS
cord-022561-rv5j1201	1730	9	of	of	IN
cord-022561-rv5j1201	1730	10	monocytes	monocyte	NNS
cord-022561-rv5j1201	1730	11	,	,	,
cord-022561-rv5j1201	1730	12	which	which	WDT
cord-022561-rv5j1201	1730	13	function	function	VBP
cord-022561-rv5j1201	1730	14	as	as	IN
cord-022561-rv5j1201	1730	15	a	a	DT
cord-022561-rv5j1201	1730	16	reserve	reserve	NN
cord-022561-rv5j1201	1730	17	for	for	IN
cord-022561-rv5j1201	1730	18	generating	generate	VBG
cord-022561-rv5j1201	1730	19	tissue	tissue	NN
cord-022561-rv5j1201	1730	20	macrophages	macrophage	NNS
cord-022561-rv5j1201	1730	21	in	in	IN
cord-022561-rv5j1201	1730	22	response	response	NN
cord-022561-rv5j1201	1730	23	to	to	IN
cord-022561-rv5j1201	1730	24	ongoing	ongoing	JJ
cord-022561-rv5j1201	1730	25	tissue	tissue	NN
cord-022561-rv5j1201	1730	26	inflammation	inflammation	NN
cord-022561-rv5j1201	1730	27	in	in	IN
cord-022561-rv5j1201	1730	28	the	the	DT
cord-022561-rv5j1201	1730	29	body	body	NN
cord-022561-rv5j1201	1730	30	.	.	.
cord-022561-rv5j1201	1731	1	White	White	NNP
cord-022561-rv5j1201	1731	2	Pulp	Pulp	NNP
cord-022561-rv5j1201	1731	3	.	.	.
cord-022561-rv5j1201	1732	1	White	white	JJ
cord-022561-rv5j1201	1732	2	pulp	pulp	NN
cord-022561-rv5j1201	1732	3	consists	consist	VBZ
cord-022561-rv5j1201	1732	4	of	of	IN
cord-022561-rv5j1201	1732	5	PALS	pals	NN
cord-022561-rv5j1201	1732	6	,	,	,
cord-022561-rv5j1201	1732	7	each	each	DT
cord-022561-rv5j1201	1732	8	with	with	IN
cord-022561-rv5j1201	1732	9	a	a	DT
cord-022561-rv5j1201	1732	10	splenic	splenic	JJ
cord-022561-rv5j1201	1732	11	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	1732	12	follicle	follicle	NN
cord-022561-rv5j1201	1732	13	surrounded	surround	VBN
cord-022561-rv5j1201	1732	14	by	by	IN
cord-022561-rv5j1201	1732	15	a	a	DT
cord-022561-rv5j1201	1732	16	marginal	marginal	JJ
cord-022561-rv5j1201	1732	17	zone	zone	NN
cord-022561-rv5j1201	1732	18	.	.	.
cord-022561-rv5j1201	1733	1	Normally	normally	RB
cord-022561-rv5j1201	1733	2	these	these	DT
cord-022561-rv5j1201	1733	3	foci	focus	NNS
cord-022561-rv5j1201	1733	4	of	of	IN
cord-022561-rv5j1201	1733	5	white	white	JJ
cord-022561-rv5j1201	1733	6	pulp	pulp	NN
cord-022561-rv5j1201	1733	7	are	be	VBP
cord-022561-rv5j1201	1733	8	so	so	RB
cord-022561-rv5j1201	1733	9	small	small	JJ
cord-022561-rv5j1201	1733	10	that	that	IN
cord-022561-rv5j1201	1733	11	they	-PRON-	PRP
cord-022561-rv5j1201	1733	12	may	may	MD
cord-022561-rv5j1201	1733	13	not	not	RB
cord-022561-rv5j1201	1733	14	be	be	VB
cord-022561-rv5j1201	1733	15	visible	visible	JJ
cord-022561-rv5j1201	1733	16	on	on	IN
cord-022561-rv5j1201	1733	17	gross	gross	JJ
cord-022561-rv5j1201	1733	18	examination	examination	NN
cord-022561-rv5j1201	1733	19	of	of	IN
cord-022561-rv5j1201	1733	20	a	a	DT
cord-022561-rv5j1201	1733	21	cross	cross	NN
cord-022561-rv5j1201	1733	22	section	section	NN
cord-022561-rv5j1201	1733	23	of	of	IN
cord-022561-rv5j1201	1733	24	the	the	DT
cord-022561-rv5j1201	1733	25	spleen	spleen	NN
cord-022561-rv5j1201	1733	26	.	.	.
cord-022561-rv5j1201	1734	1	However	however	RB
cord-022561-rv5j1201	1734	2	,	,	,
cord-022561-rv5j1201	1734	3	if	if	IN
cord-022561-rv5j1201	1734	4	nodules	nodule	NNS
cord-022561-rv5j1201	1734	5	are	be	VBP
cord-022561-rv5j1201	1734	6	enlarged	enlarge	VBN
cord-022561-rv5j1201	1734	7	either	either	CC
cord-022561-rv5j1201	1734	8	by	by	IN
cord-022561-rv5j1201	1734	9	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	1734	10	hyperplasia	hyperplasia	NN
cord-022561-rv5j1201	1734	11	,	,	,
cord-022561-rv5j1201	1734	12	amyloid	amyloid	NN
cord-022561-rv5j1201	1734	13	deposits	deposit	NNS
cord-022561-rv5j1201	1734	14	,	,	,
cord-022561-rv5j1201	1734	15	or	or	CC
cord-022561-rv5j1201	1734	16	a	a	DT
cord-022561-rv5j1201	1734	17	neoplastic	neoplastic	JJ
cord-022561-rv5j1201	1734	18	process	process	NN
cord-022561-rv5j1201	1734	19	(	(	-LRB-
cord-022561-rv5j1201	1734	20	e.g.	e.g.	RB
cord-022561-rv5j1201	1734	21	,	,	,
cord-022561-rv5j1201	1734	22	lymphoma	lymphoma	NN
cord-022561-rv5j1201	1734	23	)	)	-RRB-
cord-022561-rv5j1201	1734	24	,	,	,
cord-022561-rv5j1201	1734	25	they	-PRON-	PRP
cord-022561-rv5j1201	1734	26	can	can	MD
cord-022561-rv5j1201	1734	27	become	become	VB
cord-022561-rv5j1201	1734	28	grossly	grossly	RB
cord-022561-rv5j1201	1734	29	visible	visible	JJ
cord-022561-rv5j1201	1734	30	on	on	IN
cord-022561-rv5j1201	1734	31	the	the	DT
cord-022561-rv5j1201	1734	32	cut	cut	NN
cord-022561-rv5j1201	1734	33	surface	surface	NN
cord-022561-rv5j1201	1734	34	,	,	,
cord-022561-rv5j1201	1734	35	initially	initially	RB
cord-022561-rv5j1201	1734	36	as	as	IN
cord-022561-rv5j1201	1734	37	0.5-to	0.5-to	CD
cord-022561-rv5j1201	1734	38	1.0-mm	1.0-mm	CD
cord-022561-rv5j1201	1734	39	white	white	JJ
cord-022561-rv5j1201	1734	40	circular	circular	JJ
cord-022561-rv5j1201	1734	41	foci	focus	NNS
cord-022561-rv5j1201	1734	42	scattered	scatter	VBN
cord-022561-rv5j1201	1734	43	through	through	IN
cord-022561-rv5j1201	1734	44	the	the	DT
cord-022561-rv5j1201	1734	45	red	red	JJ
cord-022561-rv5j1201	1734	46	pulp	pulp	NN
cord-022561-rv5j1201	1734	47	.	.	.
cord-022561-rv5j1201	1735	1	In	in	IN
cord-022561-rv5j1201	1735	2	animals	animal	NNS
cord-022561-rv5j1201	1735	3	with	with	IN
cord-022561-rv5j1201	1735	4	storage	storage	NN
cord-022561-rv5j1201	1735	5	spleens	spleen	NNS
cord-022561-rv5j1201	1735	6	,	,	,
cord-022561-rv5j1201	1735	7	the	the	DT
cord-022561-rv5j1201	1735	8	The	the	DT
cord-022561-rv5j1201	1735	9	splenic	splenic	JJ
cord-022561-rv5j1201	1735	10	artery	artery	NN
cord-022561-rv5j1201	1735	11	enters	enter	VBZ
cord-022561-rv5j1201	1735	12	at	at	IN
cord-022561-rv5j1201	1735	13	the	the	DT
cord-022561-rv5j1201	1735	14	hilus	hilus	NN
cord-022561-rv5j1201	1735	15	and	and	CC
cord-022561-rv5j1201	1735	16	divides	divide	VBZ
cord-022561-rv5j1201	1735	17	into	into	IN
cord-022561-rv5j1201	1735	18	arteries	artery	NNS
cord-022561-rv5j1201	1735	19	,	,	,
cord-022561-rv5j1201	1735	20	which	which	WDT
cord-022561-rv5j1201	1735	21	enter	enter	VBP
cord-022561-rv5j1201	1735	22	the	the	DT
cord-022561-rv5j1201	1735	23	trabeculae	trabeculae	NNP
cord-022561-rv5j1201	1735	24	.	.	.
cord-022561-rv5j1201	1736	1	When	when	WRB
cord-022561-rv5j1201	1736	2	a	a	DT
cord-022561-rv5j1201	1736	3	trabecular	trabecular	JJ
cord-022561-rv5j1201	1736	4	artery	artery	NN
cord-022561-rv5j1201	1736	5	emerges	emerge	VBZ
cord-022561-rv5j1201	1736	6	from	from	IN
cord-022561-rv5j1201	1736	7	a	a	DT
cord-022561-rv5j1201	1736	8	trabecula	trabecula	NN
cord-022561-rv5j1201	1736	9	it	-PRON-	PRP
cord-022561-rv5j1201	1736	10	becomes	become	VBZ
cord-022561-rv5j1201	1736	11	the	the	DT
cord-022561-rv5j1201	1736	12	central	central	JJ
cord-022561-rv5j1201	1736	13	artery	artery	NN
cord-022561-rv5j1201	1736	14	and	and	CC
cord-022561-rv5j1201	1736	15	is	be	VBZ
cord-022561-rv5j1201	1736	16	encased	encase	VBN
cord-022561-rv5j1201	1736	17	in	in	IN
cord-022561-rv5j1201	1736	18	a	a	DT
cord-022561-rv5j1201	1736	19	periarteriolar	periarteriolar	JJ
cord-022561-rv5j1201	1736	20	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	1736	21	sheath	sheath	NN
cord-022561-rv5j1201	1736	22	(	(	-LRB-
cord-022561-rv5j1201	1736	23	PALS	pals	NN
cord-022561-rv5j1201	1736	24	)	)	-RRB-
cord-022561-rv5j1201	1736	25	,	,	,
cord-022561-rv5j1201	1736	26	which	which	WDT
cord-022561-rv5j1201	1736	27	is	be	VBZ
cord-022561-rv5j1201	1736	28	composed	compose	VBN
cord-022561-rv5j1201	1736	29	of	of	IN
cord-022561-rv5j1201	1736	30	T	T	NNP
cord-022561-rv5j1201	1736	31	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	1736	32	.	.	.
cord-022561-rv5j1201	1737	1	It	-PRON-	PRP
cord-022561-rv5j1201	1737	2	then	then	RB
cord-022561-rv5j1201	1737	3	enters	enter	VBZ
cord-022561-rv5j1201	1737	4	the	the	DT
cord-022561-rv5j1201	1737	5	splenic	splenic	JJ
cord-022561-rv5j1201	1737	6	follicle	follicle	NN
cord-022561-rv5j1201	1737	7	and	and	CC
cord-022561-rv5j1201	1737	8	gives	give	VBZ
cord-022561-rv5j1201	1737	9	off	off	RP
cord-022561-rv5j1201	1737	10	branches	branch	NNS
cord-022561-rv5j1201	1737	11	-	-	:
cord-022561-rv5j1201	1737	12	the	the	DT
cord-022561-rv5j1201	1737	13	radial	radial	JJ
cord-022561-rv5j1201	1737	14	arteries	artery	NNS
cord-022561-rv5j1201	1737	15	,	,	,
cord-022561-rv5j1201	1737	16	which	which	WDT
cord-022561-rv5j1201	1737	17	supply	supply	VBP
cord-022561-rv5j1201	1737	18	the	the	DT
cord-022561-rv5j1201	1737	19	marginal	marginal	JJ
cord-022561-rv5j1201	1737	20	sinus	sinus	NN
cord-022561-rv5j1201	1737	21	and	and	CC
cord-022561-rv5j1201	1737	22	marginal	marginal	JJ
cord-022561-rv5j1201	1737	23	zone	zone	NN
cord-022561-rv5j1201	1737	24	.	.	.
cord-022561-rv5j1201	1738	1	The	the	DT
cord-022561-rv5j1201	1738	2	central	central	JJ
cord-022561-rv5j1201	1738	3	artery	artery	NN
cord-022561-rv5j1201	1738	4	emerges	emerge	VBZ
cord-022561-rv5j1201	1738	5	from	from	IN
cord-022561-rv5j1201	1738	6	the	the	DT
cord-022561-rv5j1201	1738	7	splenic	splenic	JJ
cord-022561-rv5j1201	1738	8	follicle	follicle	NN
cord-022561-rv5j1201	1738	9	to	to	TO
cord-022561-rv5j1201	1738	10	enter	enter	VB
cord-022561-rv5j1201	1738	11	the	the	DT
cord-022561-rv5j1201	1738	12	red	red	JJ
cord-022561-rv5j1201	1738	13	pulp	pulp	NN
cord-022561-rv5j1201	1738	14	and	and	CC
cord-022561-rv5j1201	1738	15	branches	branch	NNS
cord-022561-rv5j1201	1738	16	into	into	IN
cord-022561-rv5j1201	1738	17	the	the	DT
cord-022561-rv5j1201	1738	18	penicillary	penicillary	NNP
cord-022561-rv5j1201	1738	19	arterioles	arteriole	NNS
cord-022561-rv5j1201	1738	20	,	,	,
cord-022561-rv5j1201	1738	21	which	which	WDT
cord-022561-rv5j1201	1738	22	are	be	VBP
cord-022561-rv5j1201	1738	23	enclosed	enclose	VBN
cord-022561-rv5j1201	1738	24	in	in	IN
cord-022561-rv5j1201	1738	25	a	a	DT
cord-022561-rv5j1201	1738	26	cuff	cuff	NN
cord-022561-rv5j1201	1738	27	of	of	IN
cord-022561-rv5j1201	1738	28	macrophages	macrophage	NNS
cord-022561-rv5j1201	1738	29	-	-	:
cord-022561-rv5j1201	1738	30	the	the	DT
cord-022561-rv5j1201	1738	31	periarteriolar	periarteriolar	NNP
cord-022561-rv5j1201	1738	32	macrophage	macrophage	NN
cord-022561-rv5j1201	1738	33	sheath	sheath	NN
cord-022561-rv5j1201	1738	34	(	(	-LRB-
cord-022561-rv5j1201	1738	35	PAMS	PAMS	NNP
cord-022561-rv5j1201	1738	36	)	)	-RRB-
cord-022561-rv5j1201	1738	37	.	.	.
cord-022561-rv5j1201	1739	1	The	the	DT
cord-022561-rv5j1201	1739	2	emerging	emerge	VBG
cord-022561-rv5j1201	1739	3	penicillar	penicillar	JJ
cord-022561-rv5j1201	1739	4	arteries	artery	NNS
cord-022561-rv5j1201	1739	5	branch	branch	NN
cord-022561-rv5j1201	1739	6	into	into	IN
cord-022561-rv5j1201	1739	7	arterioles	arteriole	NNS
cord-022561-rv5j1201	1739	8	and	and	CC
cord-022561-rv5j1201	1739	9	capillaries	capillary	NNS
cord-022561-rv5j1201	1739	10	that	that	WDT
cord-022561-rv5j1201	1739	11	supply	supply	VBP
cord-022561-rv5j1201	1739	12	the	the	DT
cord-022561-rv5j1201	1739	13	red	red	JJ
cord-022561-rv5j1201	1739	14	pulp	pulp	NN
cord-022561-rv5j1201	1739	15	vascular	vascular	JJ
cord-022561-rv5j1201	1739	16	spaces	space	NNS
cord-022561-rv5j1201	1739	17	(	(	-LRB-
cord-022561-rv5j1201	1739	18	see	see	VB
cord-022561-rv5j1201	1739	19	Fig	Fig	NNP
cord-022561-rv5j1201	1739	20	.	.	.
cord-022561-rv5j1201	1740	1	13	13	CD
cord-022561-rv5j1201	1740	2	-	-	SYM
cord-022561-rv5j1201	1740	3	43	43	CD
cord-022561-rv5j1201	1740	4	)	)	-RRB-
cord-022561-rv5j1201	1740	5	.	.	.
cord-022561-rv5j1201	1741	1	The	the	DT
cord-022561-rv5j1201	1741	2	red	red	JJ
cord-022561-rv5j1201	1741	3	pulp	pulp	NN
cord-022561-rv5j1201	1741	4	vascular	vascular	JJ
cord-022561-rv5j1201	1741	5	spaces	space	NNS
cord-022561-rv5j1201	1741	6	also	also	RB
cord-022561-rv5j1201	1741	7	receive	receive	VBP
cord-022561-rv5j1201	1741	8	blood	blood	NN
cord-022561-rv5j1201	1741	9	from	from	IN
cord-022561-rv5j1201	1741	10	capillaries	capillary	NNS
cord-022561-rv5j1201	1741	11	draining	drain	VBG
cord-022561-rv5j1201	1741	12	from	from	IN
cord-022561-rv5j1201	1741	13	the	the	DT
cord-022561-rv5j1201	1741	14	marginal	marginal	JJ
cord-022561-rv5j1201	1741	15	sinus	sinus	NN
cord-022561-rv5j1201	1741	16	and	and	CC
cord-022561-rv5j1201	1741	17	drain	drain	VB
cord-022561-rv5j1201	1741	18	into	into	IN
cord-022561-rv5j1201	1741	19	the	the	DT
cord-022561-rv5j1201	1741	20	splenic	splenic	JJ
cord-022561-rv5j1201	1741	21	venules	venule	NNS
cord-022561-rv5j1201	1741	22	and	and	CC
cord-022561-rv5j1201	1741	23	then	then	RB
cord-022561-rv5j1201	1741	24	into	into	IN
cord-022561-rv5j1201	1741	25	the	the	DT
cord-022561-rv5j1201	1741	26	trabecular	trabecular	JJ
cord-022561-rv5j1201	1741	27	veins	vein	NNS
cord-022561-rv5j1201	1741	28	and	and	CC
cord-022561-rv5j1201	1741	29	splenic	splenic	JJ
cord-022561-rv5j1201	1741	30	vein	vein	NN
cord-022561-rv5j1201	1741	31	.	.	.
cord-022561-rv5j1201	1742	1	B	b	NN
cord-022561-rv5j1201	1742	2	,	,	,
cord-022561-rv5j1201	1742	3	Sinusoidal	Sinusoidal	NNP
cord-022561-rv5j1201	1742	4	spleen	spleen	NNS
cord-022561-rv5j1201	1742	5	,	,	,
cord-022561-rv5j1201	1742	6	dog	dog	NN
cord-022561-rv5j1201	1742	7	.	.	.
cord-022561-rv5j1201	1743	1	The	the	DT
cord-022561-rv5j1201	1743	2	blood	blood	NN
cord-022561-rv5j1201	1743	3	flow	flow	NN
cord-022561-rv5j1201	1743	4	is	be	VBZ
cord-022561-rv5j1201	1743	5	essentially	essentially	RB
cord-022561-rv5j1201	1743	6	the	the	DT
cord-022561-rv5j1201	1743	7	same	same	JJ
cord-022561-rv5j1201	1743	8	but	but	CC
cord-022561-rv5j1201	1743	9	with	with	IN
cord-022561-rv5j1201	1743	10	the	the	DT
cord-022561-rv5j1201	1743	11	additional	additional	JJ
cord-022561-rv5j1201	1743	12	feature	feature	NN
cord-022561-rv5j1201	1743	13	that	that	WDT
cord-022561-rv5j1201	1743	14	arterioles	arterioles	RBR
cord-022561-rv5j1201	1743	15	from	from	IN
cord-022561-rv5j1201	1743	16	the	the	DT
cord-022561-rv5j1201	1743	17	marginal	marginal	JJ
cord-022561-rv5j1201	1743	18	sinus	sinus	NN
cord-022561-rv5j1201	1743	19	drain	drain	NN
cord-022561-rv5j1201	1743	20	into	into	IN
cord-022561-rv5j1201	1743	21	the	the	DT
cord-022561-rv5j1201	1743	22	sinusoids	sinusoid	NNS
cord-022561-rv5j1201	1743	23	and	and	CC
cord-022561-rv5j1201	1743	24	some	some	DT
cord-022561-rv5j1201	1743	25	blood	blood	NN
cord-022561-rv5j1201	1743	26	from	from	IN
cord-022561-rv5j1201	1743	27	the	the	DT
cord-022561-rv5j1201	1743	28	red	red	JJ
cord-022561-rv5j1201	1743	29	pulp	pulp	NN
cord-022561-rv5j1201	1743	30	vascular	vascular	JJ
cord-022561-rv5j1201	1743	31	space	space	NN
cord-022561-rv5j1201	1743	32	passes	pass	VBZ
cord-022561-rv5j1201	1743	33	through	through	IN
cord-022561-rv5j1201	1743	34	slits	slit	NNS
cord-022561-rv5j1201	1743	35	in	in	IN
cord-022561-rv5j1201	1743	36	the	the	DT
cord-022561-rv5j1201	1743	37	sinusoidal	sinusoidal	JJ
cord-022561-rv5j1201	1743	38	wall	wall	NN
cord-022561-rv5j1201	1743	39	to	to	TO
cord-022561-rv5j1201	1743	40	enter	enter	VB
cord-022561-rv5j1201	1743	41	the	the	DT
cord-022561-rv5j1201	1743	42	sinusoid	sinusoid	NN
cord-022561-rv5j1201	1743	43	(	(	-LRB-
cord-022561-rv5j1201	1743	44	see	see	VB
cord-022561-rv5j1201	1743	45	Fig	Fig	NNP
cord-022561-rv5j1201	1743	46	.	.	.
cord-022561-rv5j1201	1744	1	13	13	CD
cord-022561-rv5j1201	1744	2	-	-	SYM
cord-022561-rv5j1201	1744	3	42	42	CD
cord-022561-rv5j1201	1744	4	)	)	-RRB-
cord-022561-rv5j1201	1744	5	.	.	.
cord-022561-rv5j1201	1745	1	This	this	DT
cord-022561-rv5j1201	1745	2	is	be	VBZ
cord-022561-rv5j1201	1745	3	the	the	DT
cord-022561-rv5j1201	1745	4	site	site	NN
cord-022561-rv5j1201	1745	5	of	of	IN
cord-022561-rv5j1201	1745	6	pitting	pit	VBG
cord-022561-rv5j1201	1745	7	and	and	CC
cord-022561-rv5j1201	1745	8	erythrophagocytosis	erythrophagocytosis	NN
cord-022561-rv5j1201	1745	9	.	.	.
cord-022561-rv5j1201	1746	1	Note	note	VB
cord-022561-rv5j1201	1746	2	that	that	IN
cord-022561-rv5j1201	1746	3	the	the	DT
cord-022561-rv5j1201	1746	4	major	major	JJ
cord-022561-rv5j1201	1746	5	flow	flow	NN
cord-022561-rv5j1201	1746	6	in	in	IN
cord-022561-rv5j1201	1746	7	A	a	DT
cord-022561-rv5j1201	1746	8	is	be	VBZ
cord-022561-rv5j1201	1746	9	sequentially	sequentially	RB
cord-022561-rv5j1201	1746	10	past	past	JJ
cord-022561-rv5j1201	1746	11	concentrations	concentration	NNS
cord-022561-rv5j1201	1746	12	of	of	IN
cord-022561-rv5j1201	1746	13	macrophages	macrophage	NNS
cord-022561-rv5j1201	1746	14	in	in	IN
cord-022561-rv5j1201	1746	15	the	the	DT
cord-022561-rv5j1201	1746	16	marginal	marginal	JJ
cord-022561-rv5j1201	1746	17	sinus	sinus	NN
cord-022561-rv5j1201	1746	18	,	,	,
cord-022561-rv5j1201	1746	19	PAMS	PAMS	NNP
cord-022561-rv5j1201	1746	20	,	,	,
cord-022561-rv5j1201	1746	21	and	and	CC
cord-022561-rv5j1201	1746	22	red	red	JJ
cord-022561-rv5j1201	1746	23	pulp	pulp	NN
cord-022561-rv5j1201	1746	24	vascular	vascular	JJ
cord-022561-rv5j1201	1746	25	spaces	space	NNS
cord-022561-rv5j1201	1746	26	.	.	.
cord-022561-rv5j1201	1747	1	In	in	IN
cord-022561-rv5j1201	1747	2	B	b	NN
cord-022561-rv5j1201	1747	3	there	there	EX
cord-022561-rv5j1201	1747	4	is	be	VBZ
cord-022561-rv5j1201	1747	5	the	the	DT
cord-022561-rv5j1201	1747	6	additional	additional	JJ
cord-022561-rv5j1201	1747	7	route	route	NN
cord-022561-rv5j1201	1747	8	from	from	IN
cord-022561-rv5j1201	1747	9	the	the	DT
cord-022561-rv5j1201	1747	10	marginal	marginal	JJ
cord-022561-rv5j1201	1747	11	zone	zone	NN
cord-022561-rv5j1201	1747	12	into	into	IN
cord-022561-rv5j1201	1747	13	the	the	DT
cord-022561-rv5j1201	1747	14	sinusoids	sinusoid	NNS
cord-022561-rv5j1201	1747	15	.	.	.
cord-022561-rv5j1201	1748	1	Dog	Dog	NNP
cord-022561-rv5j1201	1748	2	.	.	.
cord-022561-rv5j1201	1749	1	Red	red	JJ
cord-022561-rv5j1201	1749	2	pulp	pulp	NN
cord-022561-rv5j1201	1749	3	vascular	vascular	JJ
cord-022561-rv5j1201	1749	4	spaces	space	NNS
cord-022561-rv5j1201	1749	5	Macrophages	macrophage	NNS
cord-022561-rv5j1201	1749	6	in	in	IN
cord-022561-rv5j1201	1749	7	the	the	DT
cord-022561-rv5j1201	1749	8	marginal	marginal	JJ
cord-022561-rv5j1201	1749	9	zone	zone	NN
cord-022561-rv5j1201	1749	10	are	be	VBP
cord-022561-rv5j1201	1749	11	phenotypically	phenotypically	RB
cord-022561-rv5j1201	1749	12	distinct	distinct	JJ
cord-022561-rv5j1201	1749	13	from	from	IN
cord-022561-rv5j1201	1749	14	those	those	DT
cord-022561-rv5j1201	1749	15	in	in	IN
cord-022561-rv5j1201	1749	16	the	the	DT
cord-022561-rv5j1201	1749	17	red	red	JJ
cord-022561-rv5j1201	1749	18	pulp	pulp	NN
cord-022561-rv5j1201	1749	19	.	.	.
cord-022561-rv5j1201	1750	1	The	the	DT
cord-022561-rv5j1201	1750	2	red	red	JJ
cord-022561-rv5j1201	1750	3	pulp	pulp	NN
cord-022561-rv5j1201	1750	4	macrophages	macrophage	NNS
cord-022561-rv5j1201	1750	5	function	function	VBP
cord-022561-rv5j1201	1750	6	primarily	primarily	RB
cord-022561-rv5j1201	1750	7	to	to	TO
cord-022561-rv5j1201	1750	8	filter	filter	VB
cord-022561-rv5j1201	1750	9	the	the	DT
cord-022561-rv5j1201	1750	10	blood	blood	NN
cord-022561-rv5j1201	1750	11	by	by	IN
cord-022561-rv5j1201	1750	12	phagocytizing	phagocytize	VBG
cord-022561-rv5j1201	1750	13	particles	particle	NNS
cord-022561-rv5j1201	1750	14	and	and	CC
cord-022561-rv5j1201	1750	15	by	by	IN
cord-022561-rv5j1201	1750	16	removing	remove	VBG
cord-022561-rv5j1201	1750	17	senescent	senescent	JJ
cord-022561-rv5j1201	1750	18	or	or	CC
cord-022561-rv5j1201	1750	19	infected	infected	JJ
cord-022561-rv5j1201	1750	20	erythrocytes	erythrocyte	NNS
cord-022561-rv5j1201	1750	21	and	and	CC
cord-022561-rv5j1201	1750	22	pathogenic	pathogenic	JJ
cord-022561-rv5j1201	1750	23	bacteria	bacteria	NNS
cord-022561-rv5j1201	1750	24	and	and	CC
cord-022561-rv5j1201	1750	25	fungi	fungus	NNS
cord-022561-rv5j1201	1750	26	.	.	.
cord-022561-rv5j1201	1751	1	Marginal	marginal	JJ
cord-022561-rv5j1201	1751	2	zone	zone	NN
cord-022561-rv5j1201	1751	3	macrophages	macrophage	NNS
cord-022561-rv5j1201	1751	4	are	be	VBP
cord-022561-rv5j1201	1751	5	divided	divide	VBN
cord-022561-rv5j1201	1751	6	into	into	IN
cord-022561-rv5j1201	1751	7	two	two	CD
cord-022561-rv5j1201	1751	8	types	type	NNS
cord-022561-rv5j1201	1751	9	based	base	VBN
cord-022561-rv5j1201	1751	10	on	on	IN
cord-022561-rv5j1201	1751	11	their	-PRON-	PRP$
cord-022561-rv5j1201	1751	12	location	location	NN
cord-022561-rv5j1201	1751	13	and	and	CC
cord-022561-rv5j1201	1751	14	the	the	DT
cord-022561-rv5j1201	1751	15	type	type	NN
cord-022561-rv5j1201	1751	16	of	of	IN
cord-022561-rv5j1201	1751	17	cell	cell	NN
cord-022561-rv5j1201	1751	18	surface	surface	NN
cord-022561-rv5j1201	1751	19	receptors	receptor	NNS
cord-022561-rv5j1201	1751	20	they	-PRON-	PRP
cord-022561-rv5j1201	1751	21	possess	possess	VBP
cord-022561-rv5j1201	1751	22	.	.	.
cord-022561-rv5j1201	1752	1	The	the	DT
cord-022561-rv5j1201	1752	2	first	first	JJ
cord-022561-rv5j1201	1752	3	group	group	NN
cord-022561-rv5j1201	1752	4	is	be	VBZ
cord-022561-rv5j1201	1752	5	positioned	position	VBN
cord-022561-rv5j1201	1752	6	toward	toward	IN
cord-022561-rv5j1201	1752	7	the	the	DT
cord-022561-rv5j1201	1752	8	periphery	periphery	NN
cord-022561-rv5j1201	1752	9	of	of	IN
cord-022561-rv5j1201	1752	10	the	the	DT
cord-022561-rv5j1201	1752	11	marginal	marginal	JJ
cord-022561-rv5j1201	1752	12	zone	zone	NN
cord-022561-rv5j1201	1752	13	,	,	,
cord-022561-rv5j1201	1752	14	whereas	whereas	IN
cord-022561-rv5j1201	1752	15	the	the	DT
cord-022561-rv5j1201	1752	16	second	second	JJ
cord-022561-rv5j1201	1752	17	group	group	NN
cord-022561-rv5j1201	1752	18	,	,	,
cord-022561-rv5j1201	1752	19	the	the	DT
cord-022561-rv5j1201	1752	20	marginal	marginal	JJ
cord-022561-rv5j1201	1752	21	metallophilic	metallophilic	NNP
cord-022561-rv5j1201	1752	22	macrophages	macrophage	NNS
cord-022561-rv5j1201	1752	23	(	(	-LRB-
cord-022561-rv5j1201	1752	24	so	so	RB
cord-022561-rv5j1201	1752	25	called	call	VBN
cord-022561-rv5j1201	1752	26	for	for	IN
cord-022561-rv5j1201	1752	27	their	-PRON-	PRP$
cord-022561-rv5j1201	1752	28	silver	silver	NN
cord-022561-rv5j1201	1752	29	staining	stain	VBG
cord-022561-rv5j1201	1752	30	positivity	positivity	NN
cord-022561-rv5j1201	1752	31	)	)	-RRB-
cord-022561-rv5j1201	1752	32	,	,	,
cord-022561-rv5j1201	1752	33	is	be	VBZ
cord-022561-rv5j1201	1752	34	at	at	IN
cord-022561-rv5j1201	1752	35	the	the	DT
cord-022561-rv5j1201	1752	36	inner	inner	JJ
cord-022561-rv5j1201	1752	37	margin	margin	NN
cord-022561-rv5j1201	1752	38	of	of	IN
cord-022561-rv5j1201	1752	39	the	the	DT
cord-022561-rv5j1201	1752	40	marginal	marginal	JJ
cord-022561-rv5j1201	1752	41	zone	zone	NN
cord-022561-rv5j1201	1752	42	closer	close	RBR
cord-022561-rv5j1201	1752	43	to	to	IN
cord-022561-rv5j1201	1752	44	the	the	DT
cord-022561-rv5j1201	1752	45	splenic	splenic	JJ
cord-022561-rv5j1201	1752	46	follicle	follicle	NN
cord-022561-rv5j1201	1752	47	and	and	CC
cord-022561-rv5j1201	1752	48	PALS	pals	NN
cord-022561-rv5j1201	1752	49	.	.	.
cord-022561-rv5j1201	1753	1	It	-PRON-	PRP
cord-022561-rv5j1201	1753	2	has	have	VBZ
cord-022561-rv5j1201	1753	3	been	be	VBN
cord-022561-rv5j1201	1753	4	difficult	difficult	JJ
cord-022561-rv5j1201	1753	5	to	to	TO
cord-022561-rv5j1201	1753	6	generate	generate	VB
cord-022561-rv5j1201	1753	7	mammalian	mammalian	JJ
cord-022561-rv5j1201	1753	8	models	model	NNS
cord-022561-rv5j1201	1753	9	that	that	WDT
cord-022561-rv5j1201	1753	10	eliminate	eliminate	VBP
cord-022561-rv5j1201	1753	11	one	one	CD
cord-022561-rv5j1201	1753	12	of	of	IN
cord-022561-rv5j1201	1753	13	the	the	DT
cord-022561-rv5j1201	1753	14	two	two	CD
cord-022561-rv5j1201	1753	15	classes	class	NNS
cord-022561-rv5j1201	1753	16	of	of	IN
cord-022561-rv5j1201	1753	17	marginal	marginal	JJ
cord-022561-rv5j1201	1753	18	zone	zone	NN
cord-022561-rv5j1201	1753	19	macrophages	macrophage	NNS
cord-022561-rv5j1201	1753	20	,	,	,
cord-022561-rv5j1201	1753	21	so	so	CC
cord-022561-rv5j1201	1753	22	the	the	DT
cord-022561-rv5j1201	1753	23	degree	degree	NN
cord-022561-rv5j1201	1753	24	to	to	TO
cord-022561-rv5j1201	1753	25	which	which	WDT
cord-022561-rv5j1201	1753	26	one	one	CD
cord-022561-rv5j1201	1753	27	group	group	NN
cord-022561-rv5j1201	1753	28	specializes	specialize	VBZ
cord-022561-rv5j1201	1753	29	in	in	IN
cord-022561-rv5j1201	1753	30	a	a	DT
cord-022561-rv5j1201	1753	31	particular	particular	JJ
cord-022561-rv5j1201	1753	32	function	function	NN
cord-022561-rv5j1201	1753	33	is	be	VBZ
cord-022561-rv5j1201	1753	34	not	not	RB
cord-022561-rv5j1201	1753	35	clear	clear	JJ
cord-022561-rv5j1201	1753	36	.	.	.
cord-022561-rv5j1201	1754	1	Some	some	DT
cord-022561-rv5j1201	1754	2	marginal	marginal	JJ
cord-022561-rv5j1201	1754	3	zone	zone	NN
cord-022561-rv5j1201	1754	4	macrophages	macrophage	NNS
cord-022561-rv5j1201	1754	5	actively	actively	RB
cord-022561-rv5j1201	1754	6	phagocytize	phagocytize	VBP
cord-022561-rv5j1201	1754	7	particulate	particulate	NN
cord-022561-rv5j1201	1754	8	matter	matter	NN
cord-022561-rv5j1201	1754	9	or	or	CC
cord-022561-rv5j1201	1754	10	bacteria	bacteria	NNS
cord-022561-rv5j1201	1754	11	(	(	-LRB-
cord-022561-rv5j1201	1754	12	e.g.	e.g.	RB
cord-022561-rv5j1201	1754	13	,	,	,
cord-022561-rv5j1201	1754	14	septicemias	septicemias	NNP
cord-022561-rv5j1201	1754	15	caused	cause	VBN
cord-022561-rv5j1201	1754	16	by	by	IN
cord-022561-rv5j1201	1754	17	Streptococcus	Streptococcus	NNP
cord-022561-rv5j1201	1754	18	pneumoniae	pneumoniae	NN
cord-022561-rv5j1201	1754	19	,	,	,
cord-022561-rv5j1201	1754	20	Listeria	Listeria	NNP
cord-022561-rv5j1201	1754	21	monocytogenes	monocytogenes	NN
cord-022561-rv5j1201	1754	22	,	,	,
cord-022561-rv5j1201	1754	23	Campylobacter	Campylobacter	NNP
cord-022561-rv5j1201	1754	24	jejuni	jejuni	NNP
cord-022561-rv5j1201	1754	25	,	,	,
cord-022561-rv5j1201	1754	26	or	or	CC
cord-022561-rv5j1201	1754	27	Bacillus	Bacillus	NNP
cord-022561-rv5j1201	1754	28	anthracis	anthracis	NN
cord-022561-rv5j1201	1754	29	)	)	-RRB-
cord-022561-rv5j1201	1754	30	in	in	IN
cord-022561-rv5j1201	1754	31	the	the	DT
cord-022561-rv5j1201	1754	32	blood	blood	NN
cord-022561-rv5j1201	1754	33	(	(	-LRB-
cord-022561-rv5j1201	1754	34	see	see	VB
cord-022561-rv5j1201	1754	35	Fig	Fig	NNP
cord-022561-rv5j1201	1754	36	.	.	NNP
cord-022561-rv5j1201	1754	37	13	13	CD
cord-022561-rv5j1201	1754	38	-	-	SYM
cord-022561-rv5j1201	1754	39	40	40	CD
cord-022561-rv5j1201	1754	40	)	)	-RRB-
cord-022561-rv5j1201	1754	41	.	.	.
cord-022561-rv5j1201	1755	1	They	-PRON-	PRP
cord-022561-rv5j1201	1755	2	also	also	RB
cord-022561-rv5j1201	1755	3	play	play	VBP
cord-022561-rv5j1201	1755	4	a	a	DT
cord-022561-rv5j1201	1755	5	similar	similar	JJ
cord-022561-rv5j1201	1755	6	role	role	NN
cord-022561-rv5j1201	1755	7	in	in	IN
cord-022561-rv5j1201	1755	8	limiting	limit	VBG
cord-022561-rv5j1201	1755	9	the	the	DT
cord-022561-rv5j1201	1755	10	spread	spread	NN
cord-022561-rv5j1201	1755	11	of	of	IN
cord-022561-rv5j1201	1755	12	viral	viral	JJ
cord-022561-rv5j1201	1755	13	infections	infection	NNS
cord-022561-rv5j1201	1755	14	.	.	.
cord-022561-rv5j1201	1756	1	Other	other	JJ
cord-022561-rv5j1201	1756	2	marginal	marginal	JJ
cord-022561-rv5j1201	1756	3	zone	zone	NN
cord-022561-rv5j1201	1756	4	macrophages	macrophage	NNS
cord-022561-rv5j1201	1756	5	phagocytize	phagocytize	NNP
cord-022561-rv5j1201	1756	6	and	and	CC
cord-022561-rv5j1201	1756	7	process	process	NN
cord-022561-rv5j1201	1756	8	antigens	antigen	NNS
cord-022561-rv5j1201	1756	9	.	.	.
cord-022561-rv5j1201	1757	1	Thus	thus	RB
cord-022561-rv5j1201	1757	2	macrophages	macrophage	NNS
cord-022561-rv5j1201	1757	3	of	of	IN
cord-022561-rv5j1201	1757	4	the	the	DT
cord-022561-rv5j1201	1757	5	marginal	marginal	JJ
cord-022561-rv5j1201	1757	6	zone	zone	NN
cord-022561-rv5j1201	1757	7	serve	serve	VB
cord-022561-rv5j1201	1757	8	to	to	TO
cord-022561-rv5j1201	1757	9	bridge	bridge	VB
cord-022561-rv5j1201	1757	10	the	the	DT
cord-022561-rv5j1201	1757	11	innate	innate	JJ
cord-022561-rv5j1201	1757	12	and	and	CC
cord-022561-rv5j1201	1757	13	adaptive	adaptive	JJ
cord-022561-rv5j1201	1757	14	immune	immune	JJ
cord-022561-rv5j1201	1757	15	responses	response	NNS
cord-022561-rv5j1201	1757	16	by	by	IN
cord-022561-rv5j1201	1757	17	secreting	secrete	VBG
cord-022561-rv5j1201	1757	18	inflammatory	inflammatory	JJ
cord-022561-rv5j1201	1757	19	cytokines	cytokine	NNS
cord-022561-rv5j1201	1757	20	to	to	TO
cord-022561-rv5j1201	1757	21	activate	activate	VB
cord-022561-rv5j1201	1757	22	other	other	JJ
cord-022561-rv5j1201	1757	23	immune	immune	JJ
cord-022561-rv5j1201	1757	24	cells	cell	NNS
cord-022561-rv5j1201	1757	25	and	and	CC
cord-022561-rv5j1201	1757	26	providing	provide	VBG
cord-022561-rv5j1201	1757	27	receptor	receptor	NN
cord-022561-rv5j1201	1757	28	-	-	HYPH
cord-022561-rv5j1201	1757	29	based	base	VBN
cord-022561-rv5j1201	1757	30	activation	activation	NN
cord-022561-rv5j1201	1757	31	of	of	IN
cord-022561-rv5j1201	1757	32	marginal	marginal	JJ
cord-022561-rv5j1201	1757	33	zone	zone	NN
cord-022561-rv5j1201	1757	34	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	1757	35	.	.	.
cord-022561-rv5j1201	1758	1	Studies	study	NNS
cord-022561-rv5j1201	1758	2	have	have	VBP
cord-022561-rv5j1201	1758	3	shown	show	VBN
cord-022561-rv5j1201	1758	4	that	that	IN
cord-022561-rv5j1201	1758	5	a	a	DT
cord-022561-rv5j1201	1758	6	loss	loss	NN
cord-022561-rv5j1201	1758	7	of	of	IN
cord-022561-rv5j1201	1758	8	marginal	marginal	JJ
cord-022561-rv5j1201	1758	9	zone	zone	NN
cord-022561-rv5j1201	1758	10	macrophages	macrophage	NNS
cord-022561-rv5j1201	1758	11	coincides	coincide	VBZ
cord-022561-rv5j1201	1758	12	with	with	IN
cord-022561-rv5j1201	1758	13	decreased	decrease	VBN
cord-022561-rv5j1201	1758	14	antigen	antigen	NN
cord-022561-rv5j1201	1758	15	trapping	trapping	NN
cord-022561-rv5j1201	1758	16	by	by	IN
cord-022561-rv5j1201	1758	17	resident	resident	NN
cord-022561-rv5j1201	1758	18	B	b	NN
cord-022561-rv5j1201	1758	19	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	1758	20	of	of	IN
cord-022561-rv5j1201	1758	21	the	the	DT
cord-022561-rv5j1201	1758	22	marginal	marginal	JJ
cord-022561-rv5j1201	1758	23	zone	zone	NN
cord-022561-rv5j1201	1758	24	and	and	CC
cord-022561-rv5j1201	1758	25	consequently	consequently	RB
cord-022561-rv5j1201	1758	26	a	a	DT
cord-022561-rv5j1201	1758	27	decrease	decrease	NN
cord-022561-rv5j1201	1758	28	in	in	IN
cord-022561-rv5j1201	1758	29	the	the	DT
cord-022561-rv5j1201	1758	30	early	early	JJ
cord-022561-rv5j1201	1758	31	IgM	IgM	NNP
cord-022561-rv5j1201	1758	32	response	response	NN
cord-022561-rv5j1201	1758	33	to	to	IN
cord-022561-rv5j1201	1758	34	antigens	antigen	NNS
cord-022561-rv5j1201	1758	35	.	.	.
cord-022561-rv5j1201	1759	1	The	the	DT
cord-022561-rv5j1201	1759	2	responses	response	NNS
cord-022561-rv5j1201	1759	3	of	of	IN
cord-022561-rv5j1201	1759	4	the	the	DT
cord-022561-rv5j1201	1759	5	spleen	spleen	NN
cord-022561-rv5j1201	1759	6	to	to	IN
cord-022561-rv5j1201	1759	7	injury	injury	NN
cord-022561-rv5j1201	1759	8	(	(	-LRB-
cord-022561-rv5j1201	1759	9	Box	Box	NNP
cord-022561-rv5j1201	1759	10	13	13	CD
cord-022561-rv5j1201	1759	11	-	-	SYM
cord-022561-rv5j1201	1759	12	8	8	CD
cord-022561-rv5j1201	1759	13	)	)	-RRB-
cord-022561-rv5j1201	1759	14	include	include	VBP
cord-022561-rv5j1201	1759	15	acute	acute	JJ
cord-022561-rv5j1201	1759	16	inflammation	inflammation	NN
cord-022561-rv5j1201	1759	17	,	,	,
cord-022561-rv5j1201	1759	18	hyperplasia	hyperplasia	NN
cord-022561-rv5j1201	1759	19	of	of	IN
cord-022561-rv5j1201	1759	20	the	the	DT
cord-022561-rv5j1201	1759	21	monocyte	monocyte	JJ
cord-022561-rv5j1201	1759	22	-	-	HYPH
cord-022561-rv5j1201	1759	23	macrophage	macrophage	NN
cord-022561-rv5j1201	1759	24	system	system	NN
cord-022561-rv5j1201	1759	25	,	,	,
cord-022561-rv5j1201	1759	26	hyperplasia	hyperplasia	NN
cord-022561-rv5j1201	1759	27	of	of	IN
cord-022561-rv5j1201	1759	28	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	1759	29	tissues	tissue	NNS
cord-022561-rv5j1201	1759	30	,	,	,
cord-022561-rv5j1201	1759	31	atrophy	atrophy	NN
cord-022561-rv5j1201	1759	32	of	of	IN
cord-022561-rv5j1201	1759	33	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	1759	34	tissues	tissue	NNS
cord-022561-rv5j1201	1759	35	,	,	,
cord-022561-rv5j1201	1759	36	storage	storage	NN
cord-022561-rv5j1201	1759	37	of	of	IN
cord-022561-rv5j1201	1759	38	blood	blood	NN
cord-022561-rv5j1201	1759	39	or	or	CC
cord-022561-rv5j1201	1759	40	contraction	contraction	NN
cord-022561-rv5j1201	1759	41	to	to	TO
cord-022561-rv5j1201	1759	42	expel	expel	VB
cord-022561-rv5j1201	1759	43	reserve	reserve	NN
cord-022561-rv5j1201	1759	44	blood	blood	NN
cord-022561-rv5j1201	1759	45	,	,	,
cord-022561-rv5j1201	1759	46	and	and	CC
cord-022561-rv5j1201	1759	47	neoplasia	neoplasia	NN
cord-022561-rv5j1201	1759	48	.	.	.
cord-022561-rv5j1201	1760	1	These	these	DT
cord-022561-rv5j1201	1760	2	responses	response	NNS
cord-022561-rv5j1201	1760	3	are	be	VBP
cord-022561-rv5j1201	1760	4	also	also	RB
cord-022561-rv5j1201	1760	5	best	well	RBS
cord-022561-rv5j1201	1760	6	considered	consider	VBN
cord-022561-rv5j1201	1760	7	on	on	IN
cord-022561-rv5j1201	1760	8	the	the	DT
cord-022561-rv5j1201	1760	9	basis	basis	NN
cord-022561-rv5j1201	1760	10	of	of	IN
cord-022561-rv5j1201	1760	11	the	the	DT
cord-022561-rv5j1201	1760	12	two	two	CD
cord-022561-rv5j1201	1760	13	main	main	JJ
cord-022561-rv5j1201	1760	14	components	component	NNS
cord-022561-rv5j1201	1760	15	of	of	IN
cord-022561-rv5j1201	1760	16	the	the	DT
cord-022561-rv5j1201	1760	17	spleen	spleen	NN
cord-022561-rv5j1201	1760	18	,	,	,
cord-022561-rv5j1201	1760	19	the	the	DT
cord-022561-rv5j1201	1760	20	red	red	JJ
cord-022561-rv5j1201	1760	21	and	and	CC
cord-022561-rv5j1201	1760	22	white	white	JJ
cord-022561-rv5j1201	1760	23	pulp	pulp	NN
cord-022561-rv5j1201	1760	24	,	,	,
cord-022561-rv5j1201	1760	25	and	and	CC
cord-022561-rv5j1201	1760	26	the	the	DT
cord-022561-rv5j1201	1760	27	anatomic	anatomic	JJ
cord-022561-rv5j1201	1760	28	systems	system	NNS
cord-022561-rv5j1201	1760	29	associated	associate	VBN
cord-022561-rv5j1201	1760	30	with	with	IN
cord-022561-rv5j1201	1760	31	each	each	DT
cord-022561-rv5j1201	1760	32	.	.	.
cord-022561-rv5j1201	1761	1	Monocyte	Monocyte	NNP
cord-022561-rv5j1201	1761	2	-	-	HYPH
cord-022561-rv5j1201	1761	3	Macrophage	Macrophage	NNP
cord-022561-rv5j1201	1761	4	System	System	NNP
cord-022561-rv5j1201	1761	5	.	.	.
cord-022561-rv5j1201	1762	1	The	the	DT
cord-022561-rv5j1201	1762	2	distribution	distribution	NN
cord-022561-rv5j1201	1762	3	and	and	CC
cord-022561-rv5j1201	1762	4	function	function	NN
cord-022561-rv5j1201	1762	5	of	of	IN
cord-022561-rv5j1201	1762	6	macrophages	macrophage	NNS
cord-022561-rv5j1201	1762	7	in	in	IN
cord-022561-rv5j1201	1762	8	the	the	DT
cord-022561-rv5j1201	1762	9	spleen	spleen	NN
cord-022561-rv5j1201	1762	10	is	be	VBZ
cord-022561-rv5j1201	1762	11	described	describe	VBN
cord-022561-rv5j1201	1762	12	earlier	early	RBR
cord-022561-rv5j1201	1762	13	in	in	IN
cord-022561-rv5j1201	1762	14	the	the	DT
cord-022561-rv5j1201	1762	15	section	section	NN
cord-022561-rv5j1201	1762	16	on	on	IN
cord-022561-rv5j1201	1762	17	Structure	Structure	NNP
cord-022561-rv5j1201	1762	18	and	and	CC
cord-022561-rv5j1201	1762	19	Function	Function	NNP
cord-022561-rv5j1201	1762	20	.	.	.
cord-022561-rv5j1201	1763	1	These	these	DT
cord-022561-rv5j1201	1763	2	interactions	interaction	NNS
cord-022561-rv5j1201	1763	3	are	be	VBP
cord-022561-rv5j1201	1763	4	complex	complex	JJ
cord-022561-rv5j1201	1763	5	,	,	,
cord-022561-rv5j1201	1763	6	and	and	CC
cord-022561-rv5j1201	1763	7	their	-PRON-	PRP$
cord-022561-rv5j1201	1763	8	relationships	relationship	NNS
cord-022561-rv5j1201	1763	9	to	to	IN
cord-022561-rv5j1201	1763	10	both	both	DT
cord-022561-rv5j1201	1763	11	innate	innate	JJ
cord-022561-rv5j1201	1763	12	and	and	CC
cord-022561-rv5j1201	1763	13	adaptive	adaptive	JJ
cord-022561-rv5j1201	1763	14	immunity	immunity	NN
cord-022561-rv5j1201	1763	15	are	be	VBP
cord-022561-rv5j1201	1763	16	areas	area	NNS
cord-022561-rv5j1201	1763	17	of	of	IN
cord-022561-rv5j1201	1763	18	intense	intense	JJ
cord-022561-rv5j1201	1763	19	study	study	NN
cord-022561-rv5j1201	1763	20	(	(	-LRB-
cord-022561-rv5j1201	1763	21	see	see	VB
cord-022561-rv5j1201	1763	22	also	also	RB
cord-022561-rv5j1201	1763	23	Chapter	chapter	NN
cord-022561-rv5j1201	1763	24	5	5	CD
cord-022561-rv5j1201	1763	25	)	)	-RRB-
cord-022561-rv5j1201	1763	26	.	.	.
cord-022561-rv5j1201	1764	1	To	to	TO
cord-022561-rv5j1201	1764	2	facilitate	facilitate	VB
cord-022561-rv5j1201	1764	3	filtering	filtering	NN
cord-022561-rv5j1201	1764	4	,	,	,
cord-022561-rv5j1201	1764	5	all	all	DT
cord-022561-rv5j1201	1764	6	of	of	IN
cord-022561-rv5j1201	1764	7	the	the	DT
cord-022561-rv5j1201	1764	8	blood	blood	NN
cord-022561-rv5j1201	1764	9	in	in	IN
cord-022561-rv5j1201	1764	10	the	the	DT
cord-022561-rv5j1201	1764	11	body	body	NN
cord-022561-rv5j1201	1764	12	passes	pass	VBZ
cord-022561-rv5j1201	1764	13	through	through	IN
cord-022561-rv5j1201	1764	14	the	the	DT
cord-022561-rv5j1201	1764	15	spleen	spleen	NN
cord-022561-rv5j1201	1764	16	at	at	IN
cord-022561-rv5j1201	1764	17	least	least	JJS
cord-022561-rv5j1201	1764	18	once	once	RB
cord-022561-rv5j1201	1764	19	a	a	DT
cord-022561-rv5j1201	1764	20	day	day	NN
cord-022561-rv5j1201	1764	21	,	,	,
cord-022561-rv5j1201	1764	22	and	and	CC
cord-022561-rv5j1201	1764	23	5	5	CD
cord-022561-rv5j1201	1764	24	%	%	NN
cord-022561-rv5j1201	1764	25	of	of	IN
cord-022561-rv5j1201	1764	26	the	the	DT
cord-022561-rv5j1201	1764	27	cardiac	cardiac	JJ
cord-022561-rv5j1201	1764	28	output	output	NN
cord-022561-rv5j1201	1764	29	goes	go	VBZ
cord-022561-rv5j1201	1764	30	to	to	IN
cord-022561-rv5j1201	1764	31	the	the	DT
cord-022561-rv5j1201	1764	32	spleen	spleen	NN
cord-022561-rv5j1201	1764	33	.	.	.
cord-022561-rv5j1201	1765	1	In	in	IN
cord-022561-rv5j1201	1765	2	dogs	dog	NNS
cord-022561-rv5j1201	1765	3	,	,	,
cord-022561-rv5j1201	1765	4	blood	blood	NN
cord-022561-rv5j1201	1765	5	flow	flow	NN
cord-022561-rv5j1201	1765	6	and	and	CC
cord-022561-rv5j1201	1765	7	transit	transit	NN
cord-022561-rv5j1201	1765	8	time	time	NN
cord-022561-rv5j1201	1765	9	depend	depend	VBP
cord-022561-rv5j1201	1765	10	on	on	IN
cord-022561-rv5j1201	1765	11	whether	whether	IN
cord-022561-rv5j1201	1765	12	the	the	DT
cord-022561-rv5j1201	1765	13	spleen	spleen	NN
cord-022561-rv5j1201	1765	14	is	be	VBZ
cord-022561-rv5j1201	1765	15	contracted	contract	VBN
cord-022561-rv5j1201	1765	16	or	or	CC
cord-022561-rv5j1201	1765	17	distended	distend	VBN
cord-022561-rv5j1201	1765	18	;	;	:
cord-022561-rv5j1201	1765	19	blood	blood	NN
cord-022561-rv5j1201	1765	20	flow	flow	NN
cord-022561-rv5j1201	1765	21	is	be	VBZ
cord-022561-rv5j1201	1765	22	slower	slow	JJR
cord-022561-rv5j1201	1765	23	in	in	IN
cord-022561-rv5j1201	1765	24	the	the	DT
cord-022561-rv5j1201	1765	25	distended	distended	JJ
cord-022561-rv5j1201	1765	26	spleen	spleen	NNS
cord-022561-rv5j1201	1765	27	.	.	.
cord-022561-rv5j1201	1766	1	The	the	DT
cord-022561-rv5j1201	1766	2	extent	extent	NN
cord-022561-rv5j1201	1766	3	to	to	TO
cord-022561-rv5j1201	1766	4	which	which	WDT
cord-022561-rv5j1201	1766	5	macrophages	macrophage	NNS
cord-022561-rv5j1201	1766	6	of	of	IN
cord-022561-rv5j1201	1766	7	the	the	DT
cord-022561-rv5j1201	1766	8	monocyte	monocyte	JJ
cord-022561-rv5j1201	1766	9	-	-	HYPH
cord-022561-rv5j1201	1766	10	macrophage	macrophage	NN
cord-022561-rv5j1201	1766	11	system	system	NN
cord-022561-rv5j1201	1766	12	phagocytize	phagocytize	NN
cord-022561-rv5j1201	1766	13	particles	particle	NNS
cord-022561-rv5j1201	1766	14	depends	depend	VBZ
cord-022561-rv5j1201	1766	15	to	to	IN
cord-022561-rv5j1201	1766	16	a	a	DT
cord-022561-rv5j1201	1766	17	large	large	JJ
cord-022561-rv5j1201	1766	18	degree	degree	NN
cord-022561-rv5j1201	1766	19	on	on	IN
cord-022561-rv5j1201	1766	20	the	the	DT
cord-022561-rv5j1201	1766	21	sequence	sequence	NN
cord-022561-rv5j1201	1766	22	in	in	IN
cord-022561-rv5j1201	1766	23	which	which	WDT
cord-022561-rv5j1201	1766	24	they	-PRON-	PRP
cord-022561-rv5j1201	1766	25	receive	receive	VBP
cord-022561-rv5j1201	1766	26	blood	blood	NN
cord-022561-rv5j1201	1766	27	.	.	.
cord-022561-rv5j1201	1767	1	In	in	IN
cord-022561-rv5j1201	1767	2	most	most	JJS
cord-022561-rv5j1201	1767	3	species	specie	NNS
cord-022561-rv5j1201	1767	4	,	,	,
cord-022561-rv5j1201	1767	5	macrophages	macrophage	NNS
cord-022561-rv5j1201	1767	6	of	of	IN
cord-022561-rv5j1201	1767	7	the	the	DT
cord-022561-rv5j1201	1767	8	marginal	marginal	JJ
cord-022561-rv5j1201	1767	9	sinus	sinus	NN
cord-022561-rv5j1201	1767	10	are	be	VBP
cord-022561-rv5j1201	1767	11	the	the	DT
cord-022561-rv5j1201	1767	12	first	first	JJ
cord-022561-rv5j1201	1767	13	to	to	TO
cord-022561-rv5j1201	1767	14	receive	receive	VB
cord-022561-rv5j1201	1767	15	blood	blood	NN
cord-022561-rv5j1201	1767	16	,	,	,
cord-022561-rv5j1201	1767	17	and	and	CC
cord-022561-rv5j1201	1767	18	consequently	consequently	RB
cord-022561-rv5j1201	1767	19	phagocytized	phagocytize	VBD
cord-022561-rv5j1201	1767	20	particles	particle	NNS
cord-022561-rv5j1201	1767	21	and	and	CC
cord-022561-rv5j1201	1767	22	bacteria	bacteria	NNS
cord-022561-rv5j1201	1767	23	tend	tend	VBP
cord-022561-rv5j1201	1767	24	to	to	TO
cord-022561-rv5j1201	1767	25	be	be	VB
cord-022561-rv5j1201	1767	26	more	more	RBR
cord-022561-rv5j1201	1767	27	concentrated	concentrated	JJ
cord-022561-rv5j1201	1767	28	here	here	RB
cord-022561-rv5j1201	1767	29	initially	initially	RB
cord-022561-rv5j1201	1767	30	.	.	.
cord-022561-rv5j1201	1768	1	However	however	RB
cord-022561-rv5j1201	1768	2	,	,	,
cord-022561-rv5j1201	1768	3	there	there	EX
cord-022561-rv5j1201	1768	4	are	be	VBP
cord-022561-rv5j1201	1768	5	differences	difference	NNS
cord-022561-rv5j1201	1768	6	among	among	IN
cord-022561-rv5j1201	1768	7	domestic	domestic	JJ
cord-022561-rv5j1201	1768	8	animal	animal	NN
cord-022561-rv5j1201	1768	9	species	specie	NNS
cord-022561-rv5j1201	1768	10	;	;	:
cord-022561-rv5j1201	1768	11	the	the	DT
cord-022561-rv5j1201	1768	12	cat	cat	NN
cord-022561-rv5j1201	1768	13	,	,	,
cord-022561-rv5j1201	1768	14	for	for	IN
cord-022561-rv5j1201	1768	15	instance	instance	NN
cord-022561-rv5j1201	1768	16	,	,	,
cord-022561-rv5j1201	1768	17	has	have	VBZ
cord-022561-rv5j1201	1768	18	a	a	DT
cord-022561-rv5j1201	1768	19	comparatively	comparatively	RB
cord-022561-rv5j1201	1768	20	small	small	JJ
cord-022561-rv5j1201	1768	21	marginal	marginal	JJ
cord-022561-rv5j1201	1768	22	sinus	sinus	NN
cord-022561-rv5j1201	1768	23	,	,	,
cord-022561-rv5j1201	1768	24	and	and	CC
cord-022561-rv5j1201	1768	25	thus	thus	RB
cord-022561-rv5j1201	1768	26	the	the	DT
cord-022561-rv5j1201	1768	27	PAMS	PAMS	NNP
cord-022561-rv5j1201	1768	28	play	play	VBP
cord-022561-rv5j1201	1768	29	a	a	DT
cord-022561-rv5j1201	1768	30	larger	large	JJR
cord-022561-rv5j1201	1768	31	role	role	NN
cord-022561-rv5j1201	1768	32	in	in	IN
cord-022561-rv5j1201	1768	33	phagocytosis	phagocytosis	NN
cord-022561-rv5j1201	1768	34	.	.	.
cord-022561-rv5j1201	1769	1	The	the	DT
cord-022561-rv5j1201	1769	2	spleen	spleen	NN
cord-022561-rv5j1201	1769	3	is	be	VBZ
cord-022561-rv5j1201	1769	4	able	able	JJ
cord-022561-rv5j1201	1769	5	to	to	TO
cord-022561-rv5j1201	1769	6	mount	mount	VB
cord-022561-rv5j1201	1769	7	a	a	DT
cord-022561-rv5j1201	1769	8	strong	strong	JJ
cord-022561-rv5j1201	1769	9	response	response	NN
cord-022561-rv5j1201	1769	10	to	to	IN
cord-022561-rv5j1201	1769	11	blood	blood	NN
cord-022561-rv5j1201	1769	12	-	-	HYPH
cord-022561-rv5j1201	1769	13	borne	bear	VBN
cord-022561-rv5j1201	1769	14	pathogens	pathogen	NNS
cord-022561-rv5j1201	1769	15	,	,	,
cord-022561-rv5j1201	1769	16	which	which	WDT
cord-022561-rv5j1201	1769	17	has	have	VBZ
cord-022561-rv5j1201	1769	18	been	be	VBN
cord-022561-rv5j1201	1769	19	demonstrated	demonstrate	VBN
cord-022561-rv5j1201	1769	20	in	in	IN
cord-022561-rv5j1201	1769	21	several	several	JJ
cord-022561-rv5j1201	1769	22	studies	study	NNS
cord-022561-rv5j1201	1769	23	.	.	.
cord-022561-rv5j1201	1770	1	The	the	DT
cord-022561-rv5j1201	1770	2	blood	blood	NN
cord-022561-rv5j1201	1770	3	of	of	IN
cord-022561-rv5j1201	1770	4	immunized	immunize	VBN
cord-022561-rv5j1201	1770	5	rabbits	rabbit	NNS
cord-022561-rv5j1201	1770	6	injected	inject	VBN
cord-022561-rv5j1201	1770	7	intravenously	intravenously	RB
cord-022561-rv5j1201	1770	8	with	with	IN
cord-022561-rv5j1201	1770	9	pneumococci	pneumococcus	NNS
cord-022561-rv5j1201	1770	10	cleared	clear	VBD
cord-022561-rv5j1201	1770	11	98	98	CD
cord-022561-rv5j1201	1770	12	%	%	NN
cord-022561-rv5j1201	1770	13	of	of	IN
cord-022561-rv5j1201	1770	14	those	those	DT
cord-022561-rv5j1201	1770	15	bacteria	bacteria	NNS
cord-022561-rv5j1201	1770	16	within	within	IN
cord-022561-rv5j1201	1770	17	15	15	CD
cord-022561-rv5j1201	1770	18	minutes	minute	NNS
cord-022561-rv5j1201	1770	19	and	and	CC
cord-022561-rv5j1201	1770	20	100	100	CD
cord-022561-rv5j1201	1770	21	%	%	NN
cord-022561-rv5j1201	1770	22	within	within	IN
cord-022561-rv5j1201	1770	23	an	an	DT
cord-022561-rv5j1201	1770	24	hour	hour	NN
cord-022561-rv5j1201	1770	25	.	.	.
cord-022561-rv5j1201	1771	1	The	the	DT
cord-022561-rv5j1201	1771	2	blood	blood	NN
cord-022561-rv5j1201	1771	3	of	of	IN
cord-022561-rv5j1201	1771	4	dogs	dog	NNS
cord-022561-rv5j1201	1771	5	injected	inject	VBN
cord-022561-rv5j1201	1771	6	with	with	IN
cord-022561-rv5j1201	1771	7	1	1	CD
cord-022561-rv5j1201	1771	8	billion	billion	CD
cord-022561-rv5j1201	1771	9	pneumococci	pneumococcus	NNS
cord-022561-rv5j1201	1771	10	per	per	IN
cord-022561-rv5j1201	1771	11	pound	pound	NN
cord-022561-rv5j1201	1771	12	of	of	IN
cord-022561-rv5j1201	1771	13	body	body	NN
cord-022561-rv5j1201	1771	14	weight	weight	NN
cord-022561-rv5j1201	1771	15	into	into	IN
cord-022561-rv5j1201	1771	16	the	the	DT
cord-022561-rv5j1201	1771	17	splenic	splenic	JJ
cord-022561-rv5j1201	1771	18	artery	artery	NN
cord-022561-rv5j1201	1771	19	was	be	VBD
cord-022561-rv5j1201	1771	20	cleared	clear	VBN
cord-022561-rv5j1201	1771	21	of	of	IN
cord-022561-rv5j1201	1771	22	all	all	DT
cord-022561-rv5j1201	1771	23	bacteria	bacteria	NNS
cord-022561-rv5j1201	1771	24	in	in	IN
cord-022561-rv5j1201	1771	25	65	65	CD
cord-022561-rv5j1201	1771	26	minutes	minute	NNS
cord-022561-rv5j1201	1771	27	.	.	.
cord-022561-rv5j1201	1772	1	After	after	IN
cord-022561-rv5j1201	1772	2	splenectomy	splenectomy	NN
cord-022561-rv5j1201	1772	3	,	,	,
cord-022561-rv5j1201	1772	4	blood	blood	NN
cord-022561-rv5j1201	1772	5	-	-	:
cord-022561-rv5j1201	1772	6	borne	bear	VBN
cord-022561-rv5j1201	1772	7	the	the	DT
cord-022561-rv5j1201	1772	8	radial	radial	JJ
cord-022561-rv5j1201	1772	9	branches	branch	NNS
cord-022561-rv5j1201	1772	10	of	of	IN
cord-022561-rv5j1201	1772	11	the	the	DT
cord-022561-rv5j1201	1772	12	central	central	JJ
cord-022561-rv5j1201	1772	13	artery	artery	NN
cord-022561-rv5j1201	1772	14	,	,	,
cord-022561-rv5j1201	1772	15	and	and	CC
cord-022561-rv5j1201	1772	16	it	-PRON-	PRP
cord-022561-rv5j1201	1772	17	serves	serve	VBZ
cord-022561-rv5j1201	1772	18	as	as	IN
cord-022561-rv5j1201	1772	19	the	the	DT
cord-022561-rv5j1201	1772	20	portal	portal	NN
cord-022561-rv5j1201	1772	21	of	of	IN
cord-022561-rv5j1201	1772	22	entry	entry	NN
cord-022561-rv5j1201	1772	23	into	into	IN
cord-022561-rv5j1201	1772	24	the	the	DT
cord-022561-rv5j1201	1772	25	spleen	spleen	NN
cord-022561-rv5j1201	1772	26	for	for	IN
cord-022561-rv5j1201	1772	27	recirculating	recirculate	VBG
cord-022561-rv5j1201	1772	28	B	b	NN
cord-022561-rv5j1201	1772	29	and	and	CC
cord-022561-rv5j1201	1772	30	T	t	NN
cord-022561-rv5j1201	1772	31	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	1772	32	.	.	.
cord-022561-rv5j1201	1773	1	From	from	IN
cord-022561-rv5j1201	1773	2	here	here	RB
cord-022561-rv5j1201	1773	3	,	,	,
cord-022561-rv5j1201	1773	4	T	t	NN
cord-022561-rv5j1201	1773	5	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	1773	6	migrate	migrate	VBP
cord-022561-rv5j1201	1773	7	to	to	IN
cord-022561-rv5j1201	1773	8	the	the	DT
cord-022561-rv5j1201	1773	9	PALS	pals	NN
cord-022561-rv5j1201	1773	10	and	and	CC
cord-022561-rv5j1201	1773	11	B	b	NN
cord-022561-rv5j1201	1773	12	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	1773	13	to	to	IN
cord-022561-rv5j1201	1773	14	the	the	DT
cord-022561-rv5j1201	1773	15	germinal	germinal	JJ
cord-022561-rv5j1201	1773	16	centers	center	NNS
cord-022561-rv5j1201	1773	17	.	.	.
cord-022561-rv5j1201	1774	1	Macrophages	macrophage	NNS
cord-022561-rv5j1201	1774	2	in	in	IN
cord-022561-rv5j1201	1774	3	the	the	DT
cord-022561-rv5j1201	1774	4	marginal	marginal	JJ
cord-022561-rv5j1201	1774	5	zone	zone	NN
cord-022561-rv5j1201	1774	6	capture	capture	NN
cord-022561-rv5j1201	1774	7	bloodborne	bloodborne	JJ
cord-022561-rv5j1201	1774	8	antigens	antigen	NNS
cord-022561-rv5j1201	1774	9	,	,	,
cord-022561-rv5j1201	1774	10	process	process	VBP
cord-022561-rv5j1201	1774	11	them	-PRON-	PRP
cord-022561-rv5j1201	1774	12	,	,	,
cord-022561-rv5j1201	1774	13	and	and	CC
cord-022561-rv5j1201	1774	14	present	present	VB
cord-022561-rv5j1201	1774	15	them	-PRON-	PRP
cord-022561-rv5j1201	1774	16	to	to	IN
cord-022561-rv5j1201	1774	17	the	the	DT
cord-022561-rv5j1201	1774	18	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	1774	19	.	.	.
cord-022561-rv5j1201	1774	20	 	 	_SP
cord-022561-rv5j1201	1775	1	Senescent	senescent	NN
cord-022561-rv5j1201	1775	2	erythrocytes	erythrocyte	NNS
cord-022561-rv5j1201	1775	3	Damaged	damage	VBN
cord-022561-rv5j1201	1775	4	erythrocytes	erythrocyte	NNS
cord-022561-rv5j1201	1775	5	(	(	-LRB-
cord-022561-rv5j1201	1775	6	e.g.	e.g.	RB
cord-022561-rv5j1201	1775	7	,	,	,
cord-022561-rv5j1201	1775	8	immune	immune	NN
cord-022561-rv5j1201	1775	9	-	-	HYPH
cord-022561-rv5j1201	1775	10	mediated	mediate	VBN
cord-022561-rv5j1201	1775	11	anemias	anemia	NNS
cord-022561-rv5j1201	1775	12	)	)	-RRB-
cord-022561-rv5j1201	1776	1	Parasitized	parasitized	JJ
cord-022561-rv5j1201	1776	2	erythrocytes	erythrocyte	NNS
cord-022561-rv5j1201	1776	3	(	(	-LRB-
cord-022561-rv5j1201	1776	4	e.g.	e.g.	RB
cord-022561-rv5j1201	1776	5	,	,	,
cord-022561-rv5j1201	1776	6	hemotropic	hemotropic	NNP
cord-022561-rv5j1201	1776	7	parasites	parasite	NNS
cord-022561-rv5j1201	1776	8	)	)	-RRB-
cord-022561-rv5j1201	1776	9	Storage	storage	NN
cord-022561-rv5j1201	1776	10	of	of	IN
cord-022561-rv5j1201	1776	11	blood	blood	NN
cord-022561-rv5j1201	1776	12	(	(	-LRB-
cord-022561-rv5j1201	1776	13	in	in	IN
cord-022561-rv5j1201	1776	14	storage	storage	NN
cord-022561-rv5j1201	1776	15	spleens	spleen	NNS
cord-022561-rv5j1201	1776	16	)	)	-RRB-
cord-022561-rv5j1201	1777	1	Extramedullary	Extramedullary	NNP
cord-022561-rv5j1201	1777	2	hematopoiesis	hematopoiesis	NN
cord-022561-rv5j1201	1777	3	Severe	severe	JJ
cord-022561-rv5j1201	1777	4	demand	demand	NN
cord-022561-rv5j1201	1777	5	(	(	-LRB-
cord-022561-rv5j1201	1777	6	e.g.	e.g.	RB
cord-022561-rv5j1201	1777	7	,	,	,
cord-022561-rv5j1201	1777	8	anemias	anemia	NNS
cord-022561-rv5j1201	1777	9	)	)	-RRB-
cord-022561-rv5j1201	1778	1	Degenerative	degenerative	JJ
cord-022561-rv5j1201	1778	2	/	/	SYM
cord-022561-rv5j1201	1778	3	inflammatory	inflammatory	JJ
cord-022561-rv5j1201	1778	4	conditions	condition	NNS
cord-022561-rv5j1201	1778	5	without	without	IN
cord-022561-rv5j1201	1778	6	concomitant	concomitant	JJ
cord-022561-rv5j1201	1778	7	hematologic	hematologic	JJ
cord-022561-rv5j1201	1778	8	disease	disease	NN
cord-022561-rv5j1201	1779	1	Incidental	incidental	JJ
cord-022561-rv5j1201	1779	2	(	(	-LRB-
cord-022561-rv5j1201	1779	3	e.g.	e.g.	RB
cord-022561-rv5j1201	1779	4	,	,	,
cord-022561-rv5j1201	1779	5	within	within	IN
cord-022561-rv5j1201	1779	6	nodules	nodule	NNS
cord-022561-rv5j1201	1779	7	of	of	IN
cord-022561-rv5j1201	1779	8	hyperplasia	hyperplasia	NN
cord-022561-rv5j1201	1779	9	)	)	-RRB-
cord-022561-rv5j1201	1779	10	Monocytes	monocyte	NNS
cord-022561-rv5j1201	1779	11	within	within	IN
cord-022561-rv5j1201	1779	12	splenic	splenic	JJ
cord-022561-rv5j1201	1779	13	cords	cord	NNS
cord-022561-rv5j1201	1779	14	Reserve	Reserve	NNP
cord-022561-rv5j1201	1779	15	for	for	IN
cord-022561-rv5j1201	1779	16	generating	generate	VBG
cord-022561-rv5j1201	1779	17	tissue	tissue	NN
cord-022561-rv5j1201	1779	18	macrophages	macrophage	NNS
cord-022561-rv5j1201	1779	19	in	in	IN
cord-022561-rv5j1201	1779	20	response	response	NN
cord-022561-rv5j1201	1779	21	to	to	IN
cord-022561-rv5j1201	1779	22	inflammation	inflammation	NN
cord-022561-rv5j1201	1779	23	Homing	homing	NN
cord-022561-rv5j1201	1779	24	of	of	IN
cord-022561-rv5j1201	1779	25	circulating	circulate	VBG
cord-022561-rv5j1201	1779	26	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	1779	27	in	in	IN
cord-022561-rv5j1201	1779	28	the	the	DT
cord-022561-rv5j1201	1779	29	blood	blood	NN
cord-022561-rv5j1201	1779	30	Phagocytosis	Phagocytosis	NNP
cord-022561-rv5j1201	1779	31	and	and	CC
cord-022561-rv5j1201	1779	32	processing	processing	NN
cord-022561-rv5j1201	1779	33	of	of	IN
cord-022561-rv5j1201	1779	34	antigen	antigen	NNP
cord-022561-rv5j1201	1779	35	Macrophage	Macrophage	NNP
cord-022561-rv5j1201	1779	36	activation	activation	NN
cord-022561-rv5j1201	1779	37	inflammation	inflammation	NN
cord-022561-rv5j1201	1779	38	,	,	,
cord-022561-rv5j1201	1779	39	which	which	WDT
cord-022561-rv5j1201	1779	40	may	may	MD
cord-022561-rv5j1201	1779	41	be	be	VB
cord-022561-rv5j1201	1779	42	diffuse	diffuse	JJ
cord-022561-rv5j1201	1779	43	or	or	CC
cord-022561-rv5j1201	1779	44	multifocal	multifocal	JJ
cord-022561-rv5j1201	1779	45	/	/	SYM
cord-022561-rv5j1201	1779	46	focal	focal	JJ
cord-022561-rv5j1201	1779	47	(	(	-LRB-
cord-022561-rv5j1201	1779	48	e.g.	e.g.	RB
cord-022561-rv5j1201	1779	49	,	,	,
cord-022561-rv5j1201	1779	50	blastomycosis	blastomycosis	NN
cord-022561-rv5j1201	1779	51	and	and	CC
cord-022561-rv5j1201	1779	52	tuberculosis	tuberculosis	NN
cord-022561-rv5j1201	1779	53	,	,	,
cord-022561-rv5j1201	1779	54	respectively	respectively	RB
cord-022561-rv5j1201	1779	55	)	)	-RRB-
cord-022561-rv5j1201	1779	56	.	.	.
cord-022561-rv5j1201	1780	1	Red	Red	NNP
cord-022561-rv5j1201	1780	2	Pulp	Pulp	NNP
cord-022561-rv5j1201	1780	3	Vascular	Vascular	NNP
cord-022561-rv5j1201	1780	4	Spaces	Spaces	NNPS
cord-022561-rv5j1201	1780	5	.	.	.
cord-022561-rv5j1201	1781	1	The	the	DT
cord-022561-rv5j1201	1781	2	main	main	JJ
cord-022561-rv5j1201	1781	3	response	response	NN
cord-022561-rv5j1201	1781	4	to	to	IN
cord-022561-rv5j1201	1781	5	injury	injury	NN
cord-022561-rv5j1201	1781	6	of	of	IN
cord-022561-rv5j1201	1781	7	the	the	DT
cord-022561-rv5j1201	1781	8	red	red	JJ
cord-022561-rv5j1201	1781	9	pulp	pulp	NN
cord-022561-rv5j1201	1781	10	vascular	vascular	JJ
cord-022561-rv5j1201	1781	11	spaces	space	NNS
cord-022561-rv5j1201	1781	12	is	be	VBZ
cord-022561-rv5j1201	1781	13	congestion	congestion	NN
cord-022561-rv5j1201	1781	14	(	(	-LRB-
cord-022561-rv5j1201	1781	15	see	see	VB
cord-022561-rv5j1201	1781	16	Uniform	Uniform	NNP
cord-022561-rv5j1201	1781	17	Splenomegaly	Splenomegaly	NNP
cord-022561-rv5j1201	1781	18	with	with	IN
cord-022561-rv5j1201	1781	19	a	a	DT
cord-022561-rv5j1201	1781	20	Bloody	Bloody	NNP
cord-022561-rv5j1201	1781	21	Consistency	Consistency	NNP
cord-022561-rv5j1201	1781	22	)	)	-RRB-
cord-022561-rv5j1201	1781	23	,	,	,
cord-022561-rv5j1201	1781	24	as	as	RB
cord-022561-rv5j1201	1781	25	well	well	RB
cord-022561-rv5j1201	1781	26	as	as	IN
cord-022561-rv5j1201	1781	27	the	the	DT
cord-022561-rv5j1201	1781	28	storage	storage	NN
cord-022561-rv5j1201	1781	29	of	of	IN
cord-022561-rv5j1201	1781	30	blood	blood	NN
cord-022561-rv5j1201	1781	31	or	or	CC
cord-022561-rv5j1201	1781	32	contraction	contraction	NN
cord-022561-rv5j1201	1781	33	to	to	TO
cord-022561-rv5j1201	1781	34	expel	expel	VB
cord-022561-rv5j1201	1781	35	reserve	reserve	JJ
cord-022561-rv5j1201	1781	36	blood	blood	NN
cord-022561-rv5j1201	1781	37	.	.	.
cord-022561-rv5j1201	1782	1	White	White	NNP
cord-022561-rv5j1201	1782	2	Pulp	Pulp	NNP
cord-022561-rv5j1201	1782	3	.	.	.
cord-022561-rv5j1201	1783	1	The	the	DT
cord-022561-rv5j1201	1783	2	responses	response	NNS
cord-022561-rv5j1201	1783	3	to	to	TO
cord-022561-rv5j1201	1783	4	injury	injury	VB
cord-022561-rv5j1201	1783	5	within	within	IN
cord-022561-rv5j1201	1783	6	the	the	DT
cord-022561-rv5j1201	1783	7	white	white	JJ
cord-022561-rv5j1201	1783	8	pulp	pulp	NN
cord-022561-rv5j1201	1783	9	are	be	VBP
cord-022561-rv5j1201	1783	10	most	most	RBS
cord-022561-rv5j1201	1783	11	pronounced	pronounce	VBN
cord-022561-rv5j1201	1783	12	in	in	IN
cord-022561-rv5j1201	1783	13	the	the	DT
cord-022561-rv5j1201	1783	14	splenic	splenic	JJ
cord-022561-rv5j1201	1783	15	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	1783	16	follicles	follicle	NNS
cord-022561-rv5j1201	1783	17	.	.	.
cord-022561-rv5j1201	1784	1	Lymphoid	lymphoid	JJ
cord-022561-rv5j1201	1784	2	follicular	follicular	JJ
cord-022561-rv5j1201	1784	3	hyperplasia	hyperplasia	NN
cord-022561-rv5j1201	1784	4	is	be	VBZ
cord-022561-rv5j1201	1784	5	a	a	DT
cord-022561-rv5j1201	1784	6	response	response	NN
cord-022561-rv5j1201	1784	7	to	to	IN
cord-022561-rv5j1201	1784	8	antigenic	antigenic	JJ
cord-022561-rv5j1201	1784	9	stimuli	stimulus	NNS
cord-022561-rv5j1201	1784	10	and	and	CC
cord-022561-rv5j1201	1784	11	results	result	NNS
cord-022561-rv5j1201	1784	12	in	in	IN
cord-022561-rv5j1201	1784	13	the	the	DT
cord-022561-rv5j1201	1784	14	formation	formation	NN
cord-022561-rv5j1201	1784	15	of	of	IN
cord-022561-rv5j1201	1784	16	secondary	secondary	JJ
cord-022561-rv5j1201	1784	17	follicles	follicle	NNS
cord-022561-rv5j1201	1784	18	;	;	,
cord-022561-rv5j1201	1784	19	marked	mark	VBN
cord-022561-rv5j1201	1784	20	hyperplasia	hyperplasia	NN
cord-022561-rv5j1201	1784	21	may	may	MD
cord-022561-rv5j1201	1784	22	be	be	VB
cord-022561-rv5j1201	1784	23	grossly	grossly	RB
cord-022561-rv5j1201	1784	24	evident	evident	JJ
cord-022561-rv5j1201	1784	25	.	.	.
cord-022561-rv5j1201	1785	1	Hyperplasia	hyperplasia	NN
cord-022561-rv5j1201	1785	2	of	of	IN
cord-022561-rv5j1201	1785	3	splenic	splenic	JJ
cord-022561-rv5j1201	1785	4	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	1785	5	follicles	follicle	NNS
cord-022561-rv5j1201	1785	6	follows	follow	VBZ
cord-022561-rv5j1201	1785	7	a	a	DT
cord-022561-rv5j1201	1785	8	similar	similar	JJ
cord-022561-rv5j1201	1785	9	sequence	sequence	NN
cord-022561-rv5j1201	1785	10	of	of	IN
cord-022561-rv5j1201	1785	11	events	event	NNS
cord-022561-rv5j1201	1785	12	and	and	CC
cord-022561-rv5j1201	1785	13	morphologic	morphologic	JJ
cord-022561-rv5j1201	1785	14	changes	change	NNS
cord-022561-rv5j1201	1785	15	as	as	IN
cord-022561-rv5j1201	1785	16	seen	see	VBN
cord-022561-rv5j1201	1785	17	in	in	IN
cord-022561-rv5j1201	1785	18	other	other	JJ
cord-022561-rv5j1201	1785	19	secondary	secondary	JJ
cord-022561-rv5j1201	1785	20	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	1785	21	organs	organ	NNS
cord-022561-rv5j1201	1785	22	and	and	CC
cord-022561-rv5j1201	1785	23	is	be	VBZ
cord-022561-rv5j1201	1785	24	discussed	discuss	VBN
cord-022561-rv5j1201	1785	25	in	in	IN
cord-022561-rv5j1201	1785	26	more	more	JJR
cord-022561-rv5j1201	1785	27	detail	detail	NN
cord-022561-rv5j1201	1785	28	in	in	IN
cord-022561-rv5j1201	1785	29	Lymphoid	Lymphoid	NNP
cord-022561-rv5j1201	1785	30	/	/	SYM
cord-022561-rv5j1201	1785	31	Lymphatic	Lymphatic	NNP
cord-022561-rv5j1201	1785	32	System	System	NNP
cord-022561-rv5j1201	1785	33	,	,	,
cord-022561-rv5j1201	1785	34	Lymph	lymph	NN
cord-022561-rv5j1201	1785	35	Nodes	node	NNS
cord-022561-rv5j1201	1785	36	,	,	,
cord-022561-rv5j1201	1785	37	Dysfunction	dysfunction	NN
cord-022561-rv5j1201	1785	38	/	/	SYM
cord-022561-rv5j1201	1785	39	Responses	response	NNS
cord-022561-rv5j1201	1785	40	to	to	IN
cord-022561-rv5j1201	1785	41	Injury	injury	NN
cord-022561-rv5j1201	1785	42	.	.	.
cord-022561-rv5j1201	1786	1	Similarly	similarly	RB
cord-022561-rv5j1201	1786	2	,	,	,
cord-022561-rv5j1201	1786	3	atrophy	atrophy	NN
cord-022561-rv5j1201	1786	4	of	of	IN
cord-022561-rv5j1201	1786	5	splenic	splenic	JJ
cord-022561-rv5j1201	1786	6	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	1786	7	follicles	follicle	NNS
cord-022561-rv5j1201	1786	8	has	have	VBZ
cord-022561-rv5j1201	1786	9	similar	similar	JJ
cord-022561-rv5j1201	1786	10	causes	cause	NNS
cord-022561-rv5j1201	1786	11	as	as	IN
cord-022561-rv5j1201	1786	12	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	1786	13	atrophy	atrophy	NN
cord-022561-rv5j1201	1786	14	in	in	IN
cord-022561-rv5j1201	1786	15	other	other	JJ
cord-022561-rv5j1201	1786	16	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	1786	17	organs	organ	NNS
cord-022561-rv5j1201	1786	18	(	(	-LRB-
cord-022561-rv5j1201	1786	19	see	see	VB
cord-022561-rv5j1201	1786	20	Box	Box	NNP
cord-022561-rv5j1201	1786	21	13	13	CD
cord-022561-rv5j1201	1786	22	-	-	SYM
cord-022561-rv5j1201	1786	23	5	5	CD
cord-022561-rv5j1201	1786	24	)	)	-RRB-
cord-022561-rv5j1201	1786	25	.	.	.
cord-022561-rv5j1201	1787	1	Briefly	briefly	RB
cord-022561-rv5j1201	1787	2	,	,	,
cord-022561-rv5j1201	1787	3	atrophy	atrophy	NN
cord-022561-rv5j1201	1787	4	occurs	occur	VBZ
cord-022561-rv5j1201	1787	5	in	in	IN
cord-022561-rv5j1201	1787	6	response	response	NN
cord-022561-rv5j1201	1787	7	to	to	IN
cord-022561-rv5j1201	1787	8	lack	lack	NN
cord-022561-rv5j1201	1787	9	of	of	IN
cord-022561-rv5j1201	1787	10	antigenic	antigenic	JJ
cord-022561-rv5j1201	1787	11	stimulation	stimulation	NN
cord-022561-rv5j1201	1787	12	(	(	-LRB-
cord-022561-rv5j1201	1787	13	e.g.	e.g.	RB
cord-022561-rv5j1201	1787	14	,	,	,
cord-022561-rv5j1201	1787	15	from	from	IN
cord-022561-rv5j1201	1787	16	regression	regression	NN
cord-022561-rv5j1201	1787	17	after	after	IN
cord-022561-rv5j1201	1787	18	antigenic	antigenic	JJ
cord-022561-rv5j1201	1787	19	stimulation	stimulation	NN
cord-022561-rv5j1201	1787	20	has	have	VBZ
cord-022561-rv5j1201	1787	21	ceased	cease	VBN
cord-022561-rv5j1201	1787	22	)	)	-RRB-
cord-022561-rv5j1201	1787	23	,	,	,
cord-022561-rv5j1201	1787	24	from	from	IN
cord-022561-rv5j1201	1787	25	the	the	DT
cord-022561-rv5j1201	1787	26	effects	effect	NNS
cord-022561-rv5j1201	1787	27	of	of	IN
cord-022561-rv5j1201	1787	28	toxins	toxin	NNS
cord-022561-rv5j1201	1787	29	,	,	,
cord-022561-rv5j1201	1787	30	antineoplastic	antineoplastic	JJ
cord-022561-rv5j1201	1787	31	chemotherapeutic	chemotherapeutic	JJ
cord-022561-rv5j1201	1787	32	agents	agent	NNS
cord-022561-rv5j1201	1787	33	,	,	,
cord-022561-rv5j1201	1787	34	microorganisms	microorganism	NNS
cord-022561-rv5j1201	1787	35	,	,	,
cord-022561-rv5j1201	1787	36	radiation	radiation	NN
cord-022561-rv5j1201	1787	37	,	,	,
cord-022561-rv5j1201	1787	38	malnutrition	malnutrition	NN
cord-022561-rv5j1201	1787	39	,	,	,
cord-022561-rv5j1201	1787	40	wasting	waste	VBG
cord-022561-rv5j1201	1787	41	/	/	SYM
cord-022561-rv5j1201	1787	42	cachectic	cachectic	JJ
cord-022561-rv5j1201	1787	43	diseases	disease	NNS
cord-022561-rv5j1201	1787	44	,	,	,
cord-022561-rv5j1201	1787	45	or	or	CC
cord-022561-rv5j1201	1787	46	aging	age	VBG
cord-022561-rv5j1201	1787	47	,	,	,
cord-022561-rv5j1201	1787	48	or	or	CC
cord-022561-rv5j1201	1787	49	when	when	WRB
cord-022561-rv5j1201	1787	50	the	the	DT
cord-022561-rv5j1201	1787	51	bone	bone	NN
cord-022561-rv5j1201	1787	52	marrow	marrow	NN
cord-022561-rv5j1201	1787	53	and	and	CC
cord-022561-rv5j1201	1787	54	thymus	thymus	NN
cord-022561-rv5j1201	1787	55	fail	fail	VBP
cord-022561-rv5j1201	1787	56	to	to	TO
cord-022561-rv5j1201	1787	57	supply	supply	VB
cord-022561-rv5j1201	1787	58	adequate	adequate	JJ
cord-022561-rv5j1201	1787	59	numbers	number	NNS
cord-022561-rv5j1201	1787	60	of	of	IN
cord-022561-rv5j1201	1787	61	B	b	NN
cord-022561-rv5j1201	1787	62	and	and	CC
cord-022561-rv5j1201	1787	63	T	t	NN
cord-022561-rv5j1201	1787	64	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	1787	65	,	,	,
cord-022561-rv5j1201	1787	66	respectively	respectively	RB
cord-022561-rv5j1201	1787	67	.	.	.
cord-022561-rv5j1201	1788	1	The	the	DT
cord-022561-rv5j1201	1788	2	follicles	follicle	NNS
cord-022561-rv5j1201	1788	3	are	be	VBP
cord-022561-rv5j1201	1788	4	depleted	deplete	VBN
cord-022561-rv5j1201	1788	5	of	of	IN
cord-022561-rv5j1201	1788	6	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	1788	7	,	,	,
cord-022561-rv5j1201	1788	8	and	and	CC
cord-022561-rv5j1201	1788	9	with	with	IN
cord-022561-rv5j1201	1788	10	time	time	NN
cord-022561-rv5j1201	1788	11	,	,	,
cord-022561-rv5j1201	1788	12	germinal	germinal	JJ
cord-022561-rv5j1201	1788	13	centers	center	NNS
cord-022561-rv5j1201	1788	14	and	and	CC
cord-022561-rv5j1201	1788	15	follicles	follicle	NNS
cord-022561-rv5j1201	1788	16	disappear	disappear	VBP
cord-022561-rv5j1201	1788	17	.	.	.
cord-022561-rv5j1201	1789	1	The	the	DT
cord-022561-rv5j1201	1789	2	amount	amount	NN
cord-022561-rv5j1201	1789	3	of	of	IN
cord-022561-rv5j1201	1789	4	the	the	DT
cord-022561-rv5j1201	1789	5	total	total	JJ
cord-022561-rv5j1201	1789	6	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	1789	7	tissue	tissue	NN
cord-022561-rv5j1201	1789	8	is	be	VBZ
cord-022561-rv5j1201	1789	9	reduced	reduce	VBN
cord-022561-rv5j1201	1789	10	,	,	,
cord-022561-rv5j1201	1789	11	and	and	CC
cord-022561-rv5j1201	1789	12	the	the	DT
cord-022561-rv5j1201	1789	13	spleen	spleen	NN
cord-022561-rv5j1201	1789	14	may	may	MD
cord-022561-rv5j1201	1789	15	be	be	VB
cord-022561-rv5j1201	1789	16	smaller	small	JJR
cord-022561-rv5j1201	1789	17	.	.	.
cord-022561-rv5j1201	1790	1	The	the	DT
cord-022561-rv5j1201	1790	2	response	response	NN
cord-022561-rv5j1201	1790	3	to	to	IN
cord-022561-rv5j1201	1790	4	injury	injury	NN
cord-022561-rv5j1201	1790	5	of	of	IN
cord-022561-rv5j1201	1790	6	the	the	DT
cord-022561-rv5j1201	1790	7	monocyte	monocyte	JJ
cord-022561-rv5j1201	1790	8	-	-	HYPH
cord-022561-rv5j1201	1790	9	macrophage	macrophage	NN
cord-022561-rv5j1201	1790	10	system	system	NN
cord-022561-rv5j1201	1790	11	in	in	IN
cord-022561-rv5j1201	1790	12	the	the	DT
cord-022561-rv5j1201	1790	13	marginal	marginal	JJ
cord-022561-rv5j1201	1790	14	sinus	sinus	NN
cord-022561-rv5j1201	1790	15	and	and	CC
cord-022561-rv5j1201	1790	16	marginal	marginal	JJ
cord-022561-rv5j1201	1790	17	zone	zone	NN
cord-022561-rv5j1201	1790	18	is	be	VBZ
cord-022561-rv5j1201	1790	19	also	also	RB
cord-022561-rv5j1201	1790	20	phagocytosis	phagocytosis	NN
cord-022561-rv5j1201	1790	21	and	and	CC
cord-022561-rv5j1201	1790	22	proliferation	proliferation	NN
cord-022561-rv5j1201	1790	23	.	.	.
cord-022561-rv5j1201	1791	1	Capsule	Capsule	NNP
cord-022561-rv5j1201	1791	2	and	and	CC
cord-022561-rv5j1201	1791	3	Trabeculae	Trabeculae	NNP
cord-022561-rv5j1201	1791	4	.	.	.
cord-022561-rv5j1201	1792	1	Lesions	lesion	NNS
cord-022561-rv5j1201	1792	2	in	in	IN
cord-022561-rv5j1201	1792	3	the	the	DT
cord-022561-rv5j1201	1792	4	capsule	capsule	NN
cord-022561-rv5j1201	1792	5	and	and	CC
cord-022561-rv5j1201	1792	6	trabeculae	trabeculae	NNP
cord-022561-rv5j1201	1792	7	are	be	VBP
cord-022561-rv5j1201	1792	8	uncommon	uncommon	JJ
cord-022561-rv5j1201	1792	9	and	and	CC
cord-022561-rv5j1201	1792	10	include	include	VBP
cord-022561-rv5j1201	1792	11	splenic	splenic	JJ
cord-022561-rv5j1201	1792	12	capsulitis	capsulitis	NN
cord-022561-rv5j1201	1792	13	secondary	secondary	JJ
cord-022561-rv5j1201	1792	14	to	to	IN
cord-022561-rv5j1201	1792	15	peritonitis	peritonitis	NN
cord-022561-rv5j1201	1792	16	,	,	,
cord-022561-rv5j1201	1792	17	and	and	CC
cord-022561-rv5j1201	1792	18	complete	complete	JJ
cord-022561-rv5j1201	1792	19	or	or	CC
cord-022561-rv5j1201	1792	20	partial	partial	JJ
cord-022561-rv5j1201	1792	21	rupture	rupture	NN
cord-022561-rv5j1201	1792	22	of	of	IN
cord-022561-rv5j1201	1792	23	the	the	DT
cord-022561-rv5j1201	1792	24	splenic	splenic	JJ
cord-022561-rv5j1201	1792	25	capsule	capsule	NN
cord-022561-rv5j1201	1792	26	,	,	,
cord-022561-rv5j1201	1792	27	usually	usually	RB
cord-022561-rv5j1201	1792	28	due	due	JJ
cord-022561-rv5j1201	1792	29	to	to	IN
cord-022561-rv5j1201	1792	30	trauma	trauma	NN
cord-022561-rv5j1201	1792	31	.	.	.
cord-022561-rv5j1201	1793	1	The	the	DT
cord-022561-rv5j1201	1793	2	two	two	CD
cord-022561-rv5j1201	1793	3	main	main	JJ
cord-022561-rv5j1201	1793	4	portals	portal	NNS
cord-022561-rv5j1201	1793	5	of	of	IN
cord-022561-rv5j1201	1793	6	entry	entry	NN
cord-022561-rv5j1201	1793	7	to	to	IN
cord-022561-rv5j1201	1793	8	the	the	DT
cord-022561-rv5j1201	1793	9	spleen	spleen	NN
cord-022561-rv5j1201	1793	10	for	for	IN
cord-022561-rv5j1201	1793	11	infectious	infectious	JJ
cord-022561-rv5j1201	1793	12	agents	agent	NNS
cord-022561-rv5j1201	1793	13	are	be	VBP
cord-022561-rv5j1201	1793	14	hematogenous	hematogenous	JJ
cord-022561-rv5j1201	1793	15	spread	spread	NN
cord-022561-rv5j1201	1793	16	and	and	CC
cord-022561-rv5j1201	1793	17	direct	direct	JJ
cord-022561-rv5j1201	1793	18	penetration	penetration	NN
cord-022561-rv5j1201	1793	19	.	.	.
cord-022561-rv5j1201	1794	1	The	the	DT
cord-022561-rv5j1201	1794	2	splenic	splenic	JJ
cord-022561-rv5j1201	1794	3	capsule	capsule	NN
cord-022561-rv5j1201	1794	4	is	be	VBZ
cord-022561-rv5j1201	1794	5	thick	thick	JJ
cord-022561-rv5j1201	1794	6	,	,	,
cord-022561-rv5j1201	1794	7	and	and	CC
cord-022561-rv5j1201	1794	8	thus	thus	RB
cord-022561-rv5j1201	1794	9	direct	direct	JJ
cord-022561-rv5j1201	1794	10	penetration	penetration	NN
cord-022561-rv5j1201	1794	11	is	be	VBZ
cord-022561-rv5j1201	1794	12	less	less	RBR
cord-022561-rv5j1201	1794	13	common	common	JJ
cord-022561-rv5j1201	1794	14	.	.	.
cord-022561-rv5j1201	1795	1	Inflammation	inflammation	NN
cord-022561-rv5j1201	1795	2	from	from	IN
cord-022561-rv5j1201	1795	3	an	an	DT
cord-022561-rv5j1201	1795	4	adjacent	adjacent	JJ
cord-022561-rv5j1201	1795	5	peritonitis	peritonitis	NN
cord-022561-rv5j1201	1795	6	is	be	VBZ
cord-022561-rv5j1201	1795	7	unlikely	unlikely	JJ
cord-022561-rv5j1201	1795	8	to	to	TO
cord-022561-rv5j1201	1795	9	penetrate	penetrate	VB
cord-022561-rv5j1201	1795	10	the	the	DT
cord-022561-rv5j1201	1795	11	capsule	capsule	NN
cord-022561-rv5j1201	1795	12	into	into	IN
cord-022561-rv5j1201	1795	13	the	the	DT
cord-022561-rv5j1201	1795	14	splenic	splenic	JJ
cord-022561-rv5j1201	1795	15	parenchyma	parenchyma	NN
cord-022561-rv5j1201	1795	16	.	.	.
cord-022561-rv5j1201	1796	1	Cattle	Cattle	NNS
cord-022561-rv5j1201	1796	2	with	with	IN
cord-022561-rv5j1201	1796	3	traumatic	traumatic	JJ
cord-022561-rv5j1201	1796	4	reticulitis	reticulitis	NN
cord-022561-rv5j1201	1796	5	may	may	MD
cord-022561-rv5j1201	1796	6	have	have	VB
cord-022561-rv5j1201	1796	7	foreign	foreign	JJ
cord-022561-rv5j1201	1796	8	objects	object	NNS
cord-022561-rv5j1201	1796	9	migrate	migrate	VB
cord-022561-rv5j1201	1796	10	into	into	IN
cord-022561-rv5j1201	1796	11	the	the	DT
cord-022561-rv5j1201	1796	12	ventral	ventral	JJ
cord-022561-rv5j1201	1796	13	extremity	extremity	NN
cord-022561-rv5j1201	1796	14	of	of	IN
cord-022561-rv5j1201	1796	15	the	the	DT
cord-022561-rv5j1201	1796	16	spleen	spleen	NN
cord-022561-rv5j1201	1796	17	,	,	,
cord-022561-rv5j1201	1796	18	causing	cause	VBG
cord-022561-rv5j1201	1796	19	a	a	DT
cord-022561-rv5j1201	1796	20	splenic	splenic	JJ
cord-022561-rv5j1201	1796	21	abscess	abscess	NN
cord-022561-rv5j1201	1796	22	.	.	.
cord-022561-rv5j1201	1797	1	Splenic	Splenic	NNP
cord-022561-rv5j1201	1797	2	abscesses	abscess	NNS
cord-022561-rv5j1201	1797	3	also	also	RB
cord-022561-rv5j1201	1797	4	develop	develop	VBP
cord-022561-rv5j1201	1797	5	secondary	secondary	JJ
cord-022561-rv5j1201	1797	6	to	to	IN
cord-022561-rv5j1201	1797	7	perforation	perforation	NN
cord-022561-rv5j1201	1797	8	of	of	IN
cord-022561-rv5j1201	1797	9	the	the	DT
cord-022561-rv5j1201	1797	10	gastric	gastric	JJ
cord-022561-rv5j1201	1797	11	wall	wall	NN
cord-022561-rv5j1201	1797	12	in	in	IN
cord-022561-rv5j1201	1797	13	horses	horse	NNS
cord-022561-rv5j1201	1797	14	,	,	,
cord-022561-rv5j1201	1797	15	due	due	IN
cord-022561-rv5j1201	1797	16	to	to	IN
cord-022561-rv5j1201	1797	17	foreign	foreign	JJ
cord-022561-rv5j1201	1797	18	body	body	NN
cord-022561-rv5j1201	1797	19	penetration	penetration	NN
cord-022561-rv5j1201	1797	20	,	,	,
cord-022561-rv5j1201	1797	21	gastric	gastric	JJ
cord-022561-rv5j1201	1797	22	ulcers	ulcer	NNS
cord-022561-rv5j1201	1797	23	,	,	,
cord-022561-rv5j1201	1797	24	or	or	CC
cord-022561-rv5j1201	1797	25	gastric	gastric	JJ
cord-022561-rv5j1201	1797	26	inflammation	inflammation	NN
cord-022561-rv5j1201	1797	27	.	.	.
cord-022561-rv5j1201	1798	1	Portals	portal	NNS
cord-022561-rv5j1201	1798	2	of	of	IN
cord-022561-rv5j1201	1798	3	entry	entry	NN
cord-022561-rv5j1201	1798	4	used	use	VBN
cord-022561-rv5j1201	1798	5	by	by	IN
cord-022561-rv5j1201	1798	6	microorganisms	microorganism	NNS
cord-022561-rv5j1201	1798	7	and	and	CC
cord-022561-rv5j1201	1798	8	other	other	JJ
cord-022561-rv5j1201	1798	9	agents	agent	NNS
cord-022561-rv5j1201	1798	10	and	and	CC
cord-022561-rv5j1201	1798	11	substances	substance	NNS
cord-022561-rv5j1201	1798	12	to	to	TO
cord-022561-rv5j1201	1798	13	access	access	VB
cord-022561-rv5j1201	1798	14	the	the	DT
cord-022561-rv5j1201	1798	15	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	1798	16	/	/	SYM
cord-022561-rv5j1201	1798	17	lymphatic	lymphatic	NN
cord-022561-rv5j1201	1798	18	system	system	NN
cord-022561-rv5j1201	1798	19	are	be	VBP
cord-022561-rv5j1201	1798	20	summarized	summarize	VBN
cord-022561-rv5j1201	1798	21	in	in	IN
cord-022561-rv5j1201	1798	22	Box	Box	NNP
cord-022561-rv5j1201	1798	23	13	13	CD
cord-022561-rv5j1201	1798	24	-	-	SYM
cord-022561-rv5j1201	1798	25	6	6	CD
cord-022561-rv5j1201	1798	26	.	.	.
cord-022561-rv5j1201	1799	1	Defense	defense	NN
cord-022561-rv5j1201	1799	2	mechanisms	mechanism	NNS
cord-022561-rv5j1201	1799	3	used	use	VBN
cord-022561-rv5j1201	1799	4	by	by	IN
cord-022561-rv5j1201	1799	5	the	the	DT
cord-022561-rv5j1201	1799	6	spleen	spleen	NN
cord-022561-rv5j1201	1799	7	to	to	TO
cord-022561-rv5j1201	1799	8	protect	protect	VB
cord-022561-rv5j1201	1799	9	itself	-PRON-	PRP
cord-022561-rv5j1201	1799	10	against	against	IN
cord-022561-rv5j1201	1799	11	microorganisms	microorganism	NNS
cord-022561-rv5j1201	1799	12	and	and	CC
cord-022561-rv5j1201	1799	13	other	other	JJ
cord-022561-rv5j1201	1799	14	agents	agent	NNS
cord-022561-rv5j1201	1799	15	are	be	VBP
cord-022561-rv5j1201	1799	16	the	the	DT
cord-022561-rv5j1201	1799	17	innate	innate	JJ
cord-022561-rv5j1201	1799	18	and	and	CC
cord-022561-rv5j1201	1799	19	adaptive	adaptive	JJ
cord-022561-rv5j1201	1799	20	immune	immune	JJ
cord-022561-rv5j1201	1799	21	responses	response	NNS
cord-022561-rv5j1201	1799	22	,	,	,
cord-022561-rv5j1201	1799	23	discussed	discuss	VBN
cord-022561-rv5j1201	1799	24	in	in	IN
cord-022561-rv5j1201	1799	25	Chapters	chapter	NNS
cord-022561-rv5j1201	1799	26	3	3	CD
cord-022561-rv5j1201	1799	27	,	,	,
cord-022561-rv5j1201	1799	28	4	4	CD
cord-022561-rv5j1201	1799	29	,	,	,
cord-022561-rv5j1201	1799	30	and	and	CC
cord-022561-rv5j1201	1799	31	5	5	CD
cord-022561-rv5j1201	1799	32	.	.	.
cord-022561-rv5j1201	1800	1	Other	other	JJ
cord-022561-rv5j1201	1800	2	defense	defense	NN
cord-022561-rv5j1201	1800	3	mechanisms	mechanism	NNS
cord-022561-rv5j1201	1800	4	are	be	VBP
cord-022561-rv5j1201	1800	5	structural	structural	JJ
cord-022561-rv5j1201	1800	6	in	in	IN
cord-022561-rv5j1201	1800	7	nature	nature	NN
cord-022561-rv5j1201	1800	8	to	to	TO
cord-022561-rv5j1201	1800	9	protect	protect	VB
cord-022561-rv5j1201	1800	10	against	against	IN
cord-022561-rv5j1201	1800	11	external	external	JJ
cord-022561-rv5j1201	1800	12	trauma	trauma	NN
cord-022561-rv5j1201	1800	13	and	and	CC
cord-022561-rv5j1201	1800	14	include	include	VBP
cord-022561-rv5j1201	1800	15	the	the	DT
cord-022561-rv5j1201	1800	16	thick	thick	JJ
cord-022561-rv5j1201	1800	17	fibrous	fibrous	JJ
cord-022561-rv5j1201	1800	18	capsule	capsule	NN
cord-022561-rv5j1201	1800	19	of	of	IN
cord-022561-rv5j1201	1800	20	the	the	DT
cord-022561-rv5j1201	1800	21	spleen	spleen	NNS
cord-022561-rv5j1201	1800	22	.	.	.
cord-022561-rv5j1201	1801	1	Lymph	lymph	NN
cord-022561-rv5j1201	1801	2	nodes	node	NNS
cord-022561-rv5j1201	1801	3	are	be	VBP
cord-022561-rv5j1201	1801	4	soft	soft	JJ
cord-022561-rv5j1201	1801	5	,	,	,
cord-022561-rv5j1201	1801	6	pale	pale	JJ
cord-022561-rv5j1201	1801	7	tan	tan	NNP
cord-022561-rv5j1201	1801	8	,	,	,
cord-022561-rv5j1201	1801	9	round	round	JJ
cord-022561-rv5j1201	1801	10	,	,	,
cord-022561-rv5j1201	1801	11	oval	oval	JJ
cord-022561-rv5j1201	1801	12	or	or	CC
cord-022561-rv5j1201	1801	13	reniform	reniform	JJ
cord-022561-rv5j1201	1801	14	organs	organ	NNS
cord-022561-rv5j1201	1801	15	with	with	IN
cord-022561-rv5j1201	1801	16	a	a	DT
cord-022561-rv5j1201	1801	17	complex	complex	JJ
cord-022561-rv5j1201	1801	18	three	three	CD
cord-022561-rv5j1201	1801	19	-	-	HYPH
cord-022561-rv5j1201	1801	20	dimensional	dimensional	JJ
cord-022561-rv5j1201	1801	21	structure	structure	NN
cord-022561-rv5j1201	1801	22	.	.	.
cord-022561-rv5j1201	1802	1	On	on	IN
cord-022561-rv5j1201	1802	2	gross	gross	JJ
cord-022561-rv5j1201	1802	3	examination	examination	NN
cord-022561-rv5j1201	1802	4	of	of	IN
cord-022561-rv5j1201	1802	5	a	a	DT
cord-022561-rv5j1201	1802	6	cross	cross	NN
cord-022561-rv5j1201	1802	7	section	section	NN
cord-022561-rv5j1201	1802	8	of	of	IN
cord-022561-rv5j1201	1802	9	lymph	lymph	NN
cord-022561-rv5j1201	1802	10	nodes	node	NNS
cord-022561-rv5j1201	1802	11	,	,	,
cord-022561-rv5j1201	1802	12	two	two	CD
cord-022561-rv5j1201	1802	13	main	main	JJ
cord-022561-rv5j1201	1802	14	areas	area	NNS
cord-022561-rv5j1201	1802	15	are	be	VBP
cord-022561-rv5j1201	1802	16	visible	visible	JJ
cord-022561-rv5j1201	1802	17	:	:	:
cord-022561-rv5j1201	1802	18	an	an	DT
cord-022561-rv5j1201	1802	19	outer	outer	JJ
cord-022561-rv5j1201	1802	20	rim	rim	NN
cord-022561-rv5j1201	1802	21	of	of	IN
cord-022561-rv5j1201	1802	22	cortex	cortex	NN
cord-022561-rv5j1201	1802	23	and	and	CC
cord-022561-rv5j1201	1802	24	an	an	DT
cord-022561-rv5j1201	1802	25	inner	inner	JJ
cord-022561-rv5j1201	1802	26	medulla	medulla	NN
cord-022561-rv5j1201	1803	1	(	(	-LRB-
cord-022561-rv5j1201	1803	2	Fig	Fig	NNP
cord-022561-rv5j1201	1803	3	.	.	.
cord-022561-rv5j1201	1803	4	13	13	CD
cord-022561-rv5j1201	1803	5	-	-	SYM
cord-022561-rv5j1201	1803	6	45	45	CD
cord-022561-rv5j1201	1803	7	)	)	-RRB-
cord-022561-rv5j1201	1803	8	.	.	.
cord-022561-rv5j1201	1804	1	To	to	TO
cord-022561-rv5j1201	1804	2	understand	understand	VB
cord-022561-rv5j1201	1804	3	the	the	DT
cord-022561-rv5j1201	1804	4	pathologic	pathologic	JJ
cord-022561-rv5j1201	1804	5	response	response	NN
cord-022561-rv5j1201	1804	6	of	of	IN
cord-022561-rv5j1201	1804	7	the	the	DT
cord-022561-rv5j1201	1804	8	lymph	lymph	NN
cord-022561-rv5j1201	1804	9	node	node	NN
cord-022561-rv5j1201	1804	10	,	,	,
cord-022561-rv5j1201	1804	11	it	-PRON-	PRP
cord-022561-rv5j1201	1804	12	is	be	VBZ
cord-022561-rv5j1201	1804	13	important	important	JJ
cord-022561-rv5j1201	1804	14	to	to	TO
cord-022561-rv5j1201	1804	15	consider	consider	VB
cord-022561-rv5j1201	1804	16	its	-PRON-	PRP$
cord-022561-rv5j1201	1804	17	anatomic	anatomic	JJ
cord-022561-rv5j1201	1804	18	components	component	NNS
cord-022561-rv5j1201	1804	19	and	and	CC
cord-022561-rv5j1201	1804	20	their	-PRON-	PRP$
cord-022561-rv5j1201	1804	21	relationship	relationship	NN
cord-022561-rv5j1201	1804	22	with	with	IN
cord-022561-rv5j1201	1804	23	antigen	antigen	NN
cord-022561-rv5j1201	1804	24	processing	processing	NN
cord-022561-rv5j1201	1804	25	(	(	-LRB-
cord-022561-rv5j1201	1804	26	Fig	Fig	NNP
cord-022561-rv5j1201	1804	27	.	.	.
cord-022561-rv5j1201	1804	28	13	13	CD
cord-022561-rv5j1201	1804	29	-	-	SYM
cord-022561-rv5j1201	1804	30	46	46	CD
cord-022561-rv5j1201	1804	31	)	)	-RRB-
cord-022561-rv5j1201	1804	32	:	:	:
cord-022561-rv5j1201	1805	1	organisms	organism	NNS
cord-022561-rv5j1201	1805	2	multiply	multiply	VBP
cord-022561-rv5j1201	1805	3	rapidly	rapidly	RB
cord-022561-rv5j1201	1805	4	and	and	CC
cord-022561-rv5j1201	1805	5	may	may	MD
cord-022561-rv5j1201	1805	6	disseminate	disseminate	VB
cord-022561-rv5j1201	1805	7	widely	widely	RB
cord-022561-rv5j1201	1805	8	in	in	IN
cord-022561-rv5j1201	1805	9	the	the	DT
cord-022561-rv5j1201	1805	10	body	body	NN
cord-022561-rv5j1201	1805	11	to	to	TO
cord-022561-rv5j1201	1805	12	cause	cause	VB
cord-022561-rv5j1201	1805	13	an	an	DT
cord-022561-rv5j1201	1805	14	overwhelming	overwhelming	JJ
cord-022561-rv5j1201	1805	15	postsplenectomy	postsplenectomy	NN
cord-022561-rv5j1201	1805	16	infection	infection	NN
cord-022561-rv5j1201	1805	17	.	.	.
cord-022561-rv5j1201	1806	1	Studies	study	NNS
cord-022561-rv5j1201	1806	2	have	have	VBP
cord-022561-rv5j1201	1806	3	also	also	RB
cord-022561-rv5j1201	1806	4	shown	show	VBN
cord-022561-rv5j1201	1806	5	that	that	IN
cord-022561-rv5j1201	1806	6	the	the	DT
cord-022561-rv5j1201	1806	7	phagocytic	phagocytic	JJ
cord-022561-rv5j1201	1806	8	function	function	NN
cord-022561-rv5j1201	1806	9	of	of	IN
cord-022561-rv5j1201	1806	10	the	the	DT
cord-022561-rv5j1201	1806	11	spleen	spleen	NN
cord-022561-rv5j1201	1806	12	is	be	VBZ
cord-022561-rv5j1201	1806	13	critical	critical	JJ
cord-022561-rv5j1201	1806	14	in	in	IN
cord-022561-rv5j1201	1806	15	the	the	DT
cord-022561-rv5j1201	1806	16	control	control	NN
cord-022561-rv5j1201	1806	17	of	of	IN
cord-022561-rv5j1201	1806	18	plasmodium	plasmodium	NN
cord-022561-rv5j1201	1806	19	(	(	-LRB-
cord-022561-rv5j1201	1806	20	causative	causative	JJ
cord-022561-rv5j1201	1806	21	agent	agent	NN
cord-022561-rv5j1201	1806	22	of	of	IN
cord-022561-rv5j1201	1806	23	malaria	malaria	NN
cord-022561-rv5j1201	1806	24	)	)	-RRB-
cord-022561-rv5j1201	1806	25	in	in	IN
cord-022561-rv5j1201	1806	26	human	human	JJ
cord-022561-rv5j1201	1806	27	beings	being	NNS
cord-022561-rv5j1201	1806	28	and	and	CC
cord-022561-rv5j1201	1806	29	babesiosis	babesiosis	NN
cord-022561-rv5j1201	1806	30	in	in	IN
cord-022561-rv5j1201	1806	31	cattle	cattle	NNS
cord-022561-rv5j1201	1806	32	.	.	.
cord-022561-rv5j1201	1807	1	If	if	IN
cord-022561-rv5j1201	1807	2	the	the	DT
cord-022561-rv5j1201	1807	3	number	number	NN
cord-022561-rv5j1201	1807	4	of	of	IN
cord-022561-rv5j1201	1807	5	pathogenic	pathogenic	JJ
cord-022561-rv5j1201	1807	6	bacteria	bacteria	NNS
cord-022561-rv5j1201	1807	7	in	in	IN
cord-022561-rv5j1201	1807	8	the	the	DT
cord-022561-rv5j1201	1807	9	circulation	circulation	NN
cord-022561-rv5j1201	1807	10	exceeds	exceed	VBZ
cord-022561-rv5j1201	1807	11	the	the	DT
cord-022561-rv5j1201	1807	12	capacity	capacity	NN
cord-022561-rv5j1201	1807	13	of	of	IN
cord-022561-rv5j1201	1807	14	the	the	DT
cord-022561-rv5j1201	1807	15	splenic	splenic	JJ
cord-022561-rv5j1201	1807	16	macrophages	macrophage	NNS
cord-022561-rv5j1201	1807	17	,	,	,
cord-022561-rv5j1201	1807	18	as	as	IN
cord-022561-rv5j1201	1807	19	in	in	IN
cord-022561-rv5j1201	1807	20	cases	case	NNS
cord-022561-rv5j1201	1807	21	of	of	IN
cord-022561-rv5j1201	1807	22	severe	severe	JJ
cord-022561-rv5j1201	1807	23	septicemia	septicemia	NN
cord-022561-rv5j1201	1807	24	,	,	,
cord-022561-rv5j1201	1807	25	it	-PRON-	PRP
cord-022561-rv5j1201	1807	26	may	may	MD
cord-022561-rv5j1201	1807	27	result	result	VB
cord-022561-rv5j1201	1807	28	in	in	IN
cord-022561-rv5j1201	1807	29	acute	acute	JJ
cord-022561-rv5j1201	1807	30	splenic	splenic	JJ
cord-022561-rv5j1201	1807	31	congestion	congestion	NN
cord-022561-rv5j1201	1807	32	(	(	-LRB-
cord-022561-rv5j1201	1807	33	see	see	VB
cord-022561-rv5j1201	1807	34	Uniform	Uniform	NNP
cord-022561-rv5j1201	1807	35	Splenomegaly	Splenomegaly	NNP
cord-022561-rv5j1201	1807	36	with	with	IN
cord-022561-rv5j1201	1807	37	a	a	DT
cord-022561-rv5j1201	1807	38	Bloody	Bloody	NNP
cord-022561-rv5j1201	1807	39	Consistency	Consistency	NNP
cord-022561-rv5j1201	1807	40	)	)	-RRB-
cord-022561-rv5j1201	1807	41	.	.	.
cord-022561-rv5j1201	1808	1	This	this	DT
cord-022561-rv5j1201	1808	2	may	may	MD
cord-022561-rv5j1201	1808	3	be	be	VB
cord-022561-rv5j1201	1808	4	followed	follow	VBN
cord-022561-rv5j1201	1808	5	by	by	IN
cord-022561-rv5j1201	1808	6	inflammation	inflammation	NN
cord-022561-rv5j1201	1808	7	with	with	IN
cord-022561-rv5j1201	1808	8	areas	area	NNS
cord-022561-rv5j1201	1808	9	of	of	IN
cord-022561-rv5j1201	1808	10	necrosis	necrosis	NN
cord-022561-rv5j1201	1808	11	,	,	,
cord-022561-rv5j1201	1808	12	fibrin	fibrin	NN
cord-022561-rv5j1201	1808	13	deposition	deposition	NN
cord-022561-rv5j1201	1808	14	,	,	,
cord-022561-rv5j1201	1808	15	and	and	CC
cord-022561-rv5j1201	1808	16	infiltration	infiltration	NN
cord-022561-rv5j1201	1808	17	by	by	IN
cord-022561-rv5j1201	1808	18	neutrophils	neutrophil	NNS
cord-022561-rv5j1201	1808	19	in	in	IN
cord-022561-rv5j1201	1808	20	bacteremias	bacteremias	NNP
cord-022561-rv5j1201	1808	21	of	of	IN
cord-022561-rv5j1201	1808	22	pyogenic	pyogenic	JJ
cord-022561-rv5j1201	1808	23	bacteria	bacteria	NNS
cord-022561-rv5j1201	1808	24	.	.	.
cord-022561-rv5j1201	1809	1	The	the	DT
cord-022561-rv5j1201	1809	2	marginal	marginal	JJ
cord-022561-rv5j1201	1809	3	zone	zone	NN
cord-022561-rv5j1201	1809	4	can	can	MD
cord-022561-rv5j1201	1809	5	be	be	VB
cord-022561-rv5j1201	1809	6	the	the	DT
cord-022561-rv5j1201	1809	7	initial	initial	JJ
cord-022561-rv5j1201	1809	8	site	site	NN
cord-022561-rv5j1201	1809	9	of	of	IN
cord-022561-rv5j1201	1809	10	response	response	NN
cord-022561-rv5j1201	1809	11	to	to	IN
cord-022561-rv5j1201	1809	12	blood	blood	NN
cord-022561-rv5j1201	1809	13	-	-	HYPH
cord-022561-rv5j1201	1809	14	borne	bear	VBN
cord-022561-rv5j1201	1809	15	antigens	antigen	NNS
cord-022561-rv5j1201	1809	16	and	and	CC
cord-022561-rv5j1201	1809	17	bacteria	bacteria	NNS
cord-022561-rv5j1201	1809	18	delivered	deliver	VBN
cord-022561-rv5j1201	1809	19	by	by	IN
cord-022561-rv5j1201	1809	20	the	the	DT
cord-022561-rv5j1201	1809	21	radial	radial	JJ
cord-022561-rv5j1201	1809	22	branches	branch	NNS
cord-022561-rv5j1201	1809	23	of	of	IN
cord-022561-rv5j1201	1809	24	the	the	DT
cord-022561-rv5j1201	1809	25	central	central	JJ
cord-022561-rv5j1201	1809	26	arteries	artery	NNS
cord-022561-rv5j1201	1809	27	to	to	IN
cord-022561-rv5j1201	1809	28	the	the	DT
cord-022561-rv5j1201	1809	29	marginal	marginal	JJ
cord-022561-rv5j1201	1809	30	sinus	sinus	NN
cord-022561-rv5j1201	1809	31	.	.	.
cord-022561-rv5j1201	1810	1	Similar	similar	JJ
cord-022561-rv5j1201	1810	2	to	to	IN
cord-022561-rv5j1201	1810	3	the	the	DT
cord-022561-rv5j1201	1810	4	response	response	NN
cord-022561-rv5j1201	1810	5	of	of	IN
cord-022561-rv5j1201	1810	6	the	the	DT
cord-022561-rv5j1201	1810	7	red	red	JJ
cord-022561-rv5j1201	1810	8	pulp	pulp	NN
cord-022561-rv5j1201	1810	9	vascular	vascular	JJ
cord-022561-rv5j1201	1810	10	spaces	space	NNS
cord-022561-rv5j1201	1810	11	,	,	,
cord-022561-rv5j1201	1810	12	the	the	DT
cord-022561-rv5j1201	1810	13	marginal	marginal	JJ
cord-022561-rv5j1201	1810	14	zone	zone	NN
cord-022561-rv5j1201	1810	15	can	can	MD
cord-022561-rv5j1201	1810	16	become	become	VB
cord-022561-rv5j1201	1810	17	congested	congested	JJ
cord-022561-rv5j1201	1810	18	and	and	CC
cord-022561-rv5j1201	1810	19	with	with	IN
cord-022561-rv5j1201	1810	20	time	time	NN
cord-022561-rv5j1201	1810	21	(	(	-LRB-
cord-022561-rv5j1201	1810	22	only	only	RB
cord-022561-rv5j1201	1810	23	hours	hour	NNS
cord-022561-rv5j1201	1810	24	with	with	IN
cord-022561-rv5j1201	1810	25	highly	highly	RB
cord-022561-rv5j1201	1810	26	pathogenic	pathogenic	JJ
cord-022561-rv5j1201	1810	27	organisms	organism	NNS
cord-022561-rv5j1201	1810	28	)	)	-RRB-
cord-022561-rv5j1201	1810	29	may	may	MD
cord-022561-rv5j1201	1810	30	contain	contain	VB
cord-022561-rv5j1201	1810	31	aggregates	aggregate	NNS
cord-022561-rv5j1201	1810	32	of	of	IN
cord-022561-rv5j1201	1810	33	neutrophils	neutrophil	NNS
cord-022561-rv5j1201	1810	34	and	and	CC
cord-022561-rv5j1201	1810	35	macrophages	macrophage	NNS
cord-022561-rv5j1201	1810	36	.	.	.
cord-022561-rv5j1201	1811	1	Histologically	histologically	RB
cord-022561-rv5j1201	1811	2	,	,	,
cord-022561-rv5j1201	1811	3	the	the	DT
cord-022561-rv5j1201	1811	4	congestion	congestion	NN
cord-022561-rv5j1201	1811	5	and	and	CC
cord-022561-rv5j1201	1811	6	inflammation	inflammation	NN
cord-022561-rv5j1201	1811	7	form	form	VB
cord-022561-rv5j1201	1811	8	a	a	DT
cord-022561-rv5j1201	1811	9	complete	complete	JJ
cord-022561-rv5j1201	1811	10	or	or	CC
cord-022561-rv5j1201	1811	11	partial	partial	JJ
cord-022561-rv5j1201	1811	12	concentric	concentric	JJ
cord-022561-rv5j1201	1811	13	ring	ring	NN
cord-022561-rv5j1201	1811	14	around	around	IN
cord-022561-rv5j1201	1811	15	the	the	DT
cord-022561-rv5j1201	1811	16	circumference	circumference	NN
cord-022561-rv5j1201	1811	17	of	of	IN
cord-022561-rv5j1201	1811	18	the	the	DT
cord-022561-rv5j1201	1811	19	splenic	splenic	JJ
cord-022561-rv5j1201	1811	20	nodule	nodule	NN
cord-022561-rv5j1201	1811	21	(	(	-LRB-
cord-022561-rv5j1201	1811	22	see	see	VB
cord-022561-rv5j1201	1811	23	Anthrax	Anthrax	NNP
cord-022561-rv5j1201	1811	24	)	)	-RRB-
cord-022561-rv5j1201	1811	25	.	.	.
cord-022561-rv5j1201	1812	1	Hyperplasia	hyperplasia	NN
cord-022561-rv5j1201	1812	2	of	of	IN
cord-022561-rv5j1201	1812	3	the	the	DT
cord-022561-rv5j1201	1812	4	red	red	JJ
cord-022561-rv5j1201	1812	5	pulp	pulp	NN
cord-022561-rv5j1201	1812	6	macrophages	macrophage	NNS
cord-022561-rv5j1201	1812	7	is	be	VBZ
cord-022561-rv5j1201	1812	8	also	also	RB
cord-022561-rv5j1201	1812	9	seen	see	VBN
cord-022561-rv5j1201	1812	10	in	in	IN
cord-022561-rv5j1201	1812	11	chronic	chronic	JJ
cord-022561-rv5j1201	1812	12	hemolytic	hemolytic	JJ
cord-022561-rv5j1201	1812	13	diseases	disease	NNS
cord-022561-rv5j1201	1812	14	,	,	,
cord-022561-rv5j1201	1812	15	because	because	IN
cord-022561-rv5j1201	1812	16	there	there	EX
cord-022561-rv5j1201	1812	17	is	be	VBZ
cord-022561-rv5j1201	1812	18	a	a	DT
cord-022561-rv5j1201	1812	19	prolonged	prolonged	JJ
cord-022561-rv5j1201	1812	20	need	need	NN
cord-022561-rv5j1201	1812	21	for	for	IN
cord-022561-rv5j1201	1812	22	phagocytosis	phagocytosis	NN
cord-022561-rv5j1201	1812	23	of	of	IN
cord-022561-rv5j1201	1812	24	erythrocytes	erythrocyte	NNS
cord-022561-rv5j1201	1812	25	.	.	.
cord-022561-rv5j1201	1813	1	Similarly	similarly	RB
cord-022561-rv5j1201	1813	2	,	,	,
cord-022561-rv5j1201	1813	3	chronic	chronic	JJ
cord-022561-rv5j1201	1813	4	splenic	splenic	JJ
cord-022561-rv5j1201	1813	5	congestion	congestion	NN
cord-022561-rv5j1201	1813	6	,	,	,
cord-022561-rv5j1201	1813	7	usually	usually	RB
cord-022561-rv5j1201	1813	8	the	the	DT
cord-022561-rv5j1201	1813	9	result	result	NN
cord-022561-rv5j1201	1813	10	of	of	IN
cord-022561-rv5j1201	1813	11	portal	portal	JJ
cord-022561-rv5j1201	1813	12	or	or	CC
cord-022561-rv5j1201	1813	13	splenic	splenic	JJ
cord-022561-rv5j1201	1813	14	vein	vein	NN
cord-022561-rv5j1201	1813	15	hypertension	hypertension	NN
cord-022561-rv5j1201	1813	16	,	,	,
cord-022561-rv5j1201	1813	17	can	can	MD
cord-022561-rv5j1201	1813	18	lead	lead	VB
cord-022561-rv5j1201	1813	19	to	to	IN
cord-022561-rv5j1201	1813	20	proliferation	proliferation	NN
cord-022561-rv5j1201	1813	21	of	of	IN
cord-022561-rv5j1201	1813	22	the	the	DT
cord-022561-rv5j1201	1813	23	macrophages	macrophage	NNS
cord-022561-rv5j1201	1813	24	present	present	JJ
cord-022561-rv5j1201	1813	25	on	on	IN
cord-022561-rv5j1201	1813	26	the	the	DT
cord-022561-rv5j1201	1813	27	walls	wall	NNS
cord-022561-rv5j1201	1813	28	of	of	IN
cord-022561-rv5j1201	1813	29	the	the	DT
cord-022561-rv5j1201	1813	30	red	red	JJ
cord-022561-rv5j1201	1813	31	pulp	pulp	NN
cord-022561-rv5j1201	1813	32	vascular	vascular	JJ
cord-022561-rv5j1201	1813	33	spaces	space	NNS
cord-022561-rv5j1201	1813	34	and	and	CC
cord-022561-rv5j1201	1813	35	results	result	NNS
cord-022561-rv5j1201	1813	36	in	in	IN
cord-022561-rv5j1201	1813	37	thickening	thickening	NN
cord-022561-rv5j1201	1813	38	of	of	IN
cord-022561-rv5j1201	1813	39	the	the	DT
cord-022561-rv5j1201	1813	40	reticular	reticular	JJ
cord-022561-rv5j1201	1813	41	walls	wall	NNS
cord-022561-rv5j1201	1813	42	between	between	IN
cord-022561-rv5j1201	1813	43	the	the	DT
cord-022561-rv5j1201	1813	44	red	red	JJ
cord-022561-rv5j1201	1813	45	pulp	pulp	NN
cord-022561-rv5j1201	1813	46	vascular	vascular	JJ
cord-022561-rv5j1201	1813	47	spaces	space	NNS
cord-022561-rv5j1201	1813	48	.	.	.
cord-022561-rv5j1201	1814	1	Macrophages	macrophage	NNS
cord-022561-rv5j1201	1814	2	in	in	IN
cord-022561-rv5j1201	1814	3	the	the	DT
cord-022561-rv5j1201	1814	4	red	red	JJ
cord-022561-rv5j1201	1814	5	pulp	pulp	NN
cord-022561-rv5j1201	1814	6	also	also	RB
cord-022561-rv5j1201	1814	7	proliferate	proliferate	VBP
cord-022561-rv5j1201	1814	8	in	in	IN
cord-022561-rv5j1201	1814	9	response	response	NN
cord-022561-rv5j1201	1814	10	to	to	IN
cord-022561-rv5j1201	1814	11	fungi	fungus	NNS
cord-022561-rv5j1201	1814	12	and	and	CC
cord-022561-rv5j1201	1814	13	facultative	facultative	JJ
cord-022561-rv5j1201	1814	14	intracellular	intracellular	JJ
cord-022561-rv5j1201	1814	15	pathogens	pathogen	NNS
cord-022561-rv5j1201	1814	16	(	(	-LRB-
cord-022561-rv5j1201	1814	17	e.g.	e.g.	RB
cord-022561-rv5j1201	1814	18	,	,	,
cord-022561-rv5j1201	1814	19	Mycobacterium	Mycobacterium	NNP
cord-022561-rv5j1201	1814	20	bovis	bovis	NN
cord-022561-rv5j1201	1814	21	)	)	-RRB-
cord-022561-rv5j1201	1814	22	arriving	arrive	VBG
cord-022561-rv5j1201	1814	23	hematogenously	hematogenously	RB
cord-022561-rv5j1201	1814	24	to	to	IN
cord-022561-rv5j1201	1814	25	the	the	DT
cord-022561-rv5j1201	1814	26	spleen	spleen	NN
cord-022561-rv5j1201	1814	27	.	.	.
cord-022561-rv5j1201	1815	1	The	the	DT
cord-022561-rv5j1201	1815	2	number	number	NN
cord-022561-rv5j1201	1815	3	of	of	IN
cord-022561-rv5j1201	1815	4	red	red	JJ
cord-022561-rv5j1201	1815	5	pulp	pulp	NN
cord-022561-rv5j1201	1815	6	macrophages	macrophage	NNS
cord-022561-rv5j1201	1815	7	may	may	MD
cord-022561-rv5j1201	1815	8	be	be	VB
cord-022561-rv5j1201	1815	9	augmented	augment	VBN
cord-022561-rv5j1201	1815	10	by	by	IN
cord-022561-rv5j1201	1815	11	monocytes	monocyte	NNS
cord-022561-rv5j1201	1815	12	recruited	recruit	VBN
cord-022561-rv5j1201	1815	13	from	from	IN
cord-022561-rv5j1201	1815	14	the	the	DT
cord-022561-rv5j1201	1815	15	blood	blood	NN
cord-022561-rv5j1201	1815	16	to	to	TO
cord-022561-rv5j1201	1815	17	form	form	VB
cord-022561-rv5j1201	1815	18	granulomatous	granulomatous	JJ
cord-022561-rv5j1201	1815	19	Acute	acute	JJ
cord-022561-rv5j1201	1815	20	inflammation	inflammation	NN
cord-022561-rv5j1201	1815	21	with	with	IN
cord-022561-rv5j1201	1815	22	fibrin	fibrin	NN
cord-022561-rv5j1201	1815	23	and	and	CC
cord-022561-rv5j1201	1815	24	necrosis	necrosis	NN
cord-022561-rv5j1201	1815	25	Abscesses	abscess	NNS
cord-022561-rv5j1201	1815	26	,	,	,
cord-022561-rv5j1201	1815	27	microabscesses	microabscesse	NNS
cord-022561-rv5j1201	1815	28	Granulomatous	granulomatous	JJ
cord-022561-rv5j1201	1815	29	inflammation	inflammation	NN
cord-022561-rv5j1201	1815	30	(	(	-LRB-
cord-022561-rv5j1201	1815	31	diffuse	diffuse	JJ
cord-022561-rv5j1201	1815	32	,	,	,
cord-022561-rv5j1201	1815	33	multifocal	multifocal	JJ
cord-022561-rv5j1201	1815	34	,	,	,
cord-022561-rv5j1201	1815	35	focal	focal	JJ
cord-022561-rv5j1201	1815	36	)	)	-RRB-
cord-022561-rv5j1201	1815	37	fibroblastic	fibroblastic	JJ
cord-022561-rv5j1201	1815	38	reticular	reticular	JJ
cord-022561-rv5j1201	1815	39	cells	cell	NNS
cord-022561-rv5j1201	1815	40	and	and	CC
cord-022561-rv5j1201	1815	41	fibers	fiber	NNS
cord-022561-rv5j1201	1815	42	.	.	.
cord-022561-rv5j1201	1816	1	Besides	besides	IN
cord-022561-rv5j1201	1816	2	providing	provide	VBG
cord-022561-rv5j1201	1816	3	structural	structural	JJ
cord-022561-rv5j1201	1816	4	support	support	NN
cord-022561-rv5j1201	1816	5	,	,	,
cord-022561-rv5j1201	1816	6	this	this	DT
cord-022561-rv5j1201	1816	7	reticulum	reticulum	NN
cord-022561-rv5j1201	1816	8	helps	help	VBZ
cord-022561-rv5j1201	1816	9	form	form	VB
cord-022561-rv5j1201	1816	10	a	a	DT
cord-022561-rv5j1201	1816	11	substratum	substratum	NN
cord-022561-rv5j1201	1816	12	for	for	IN
cord-022561-rv5j1201	1816	13	the	the	DT
cord-022561-rv5j1201	1816	14	migration	migration	NN
cord-022561-rv5j1201	1816	15	of	of	IN
cord-022561-rv5j1201	1816	16	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	1816	17	and	and	CC
cord-022561-rv5j1201	1816	18	antigen	antigen	NN
cord-022561-rv5j1201	1816	19	-	-	HYPH
cord-022561-rv5j1201	1816	20	presenting	present	VBG
cord-022561-rv5j1201	1816	21	cells	cell	NNS
cord-022561-rv5j1201	1816	22	to	to	IN
cord-022561-rv5j1201	1816	23	the	the	DT
cord-022561-rv5j1201	1816	24	follicles	follicle	NNS
cord-022561-rv5j1201	1816	25	and	and	CC
cord-022561-rv5j1201	1816	26	facilitates	facilitate	VBZ
cord-022561-rv5j1201	1816	27	the	the	DT
cord-022561-rv5j1201	1816	28	interaction	interaction	NN
cord-022561-rv5j1201	1816	29	with	with	IN
cord-022561-rv5j1201	1816	30	B	B	NNP
cord-022561-rv5j1201	1816	31	and	and	CC
cord-022561-rv5j1201	1816	32	T	t	NN
cord-022561-rv5j1201	1816	33	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	1816	34	.	.	.
cord-022561-rv5j1201	1817	1	Cortex	Cortex	NNP
cord-022561-rv5j1201	1817	2	.	.	.
cord-022561-rv5j1201	1818	1	The	the	DT
cord-022561-rv5j1201	1818	2	outer	outer	JJ
cord-022561-rv5j1201	1818	3	/	/	SYM
cord-022561-rv5j1201	1818	4	superficial	superficial	JJ
cord-022561-rv5j1201	1818	5	cortex	cortex	NN
cord-022561-rv5j1201	1818	6	contains	contain	VBZ
cord-022561-rv5j1201	1818	7	the	the	DT
cord-022561-rv5j1201	1818	8	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	1818	9	follicles	follicle	NNS
cord-022561-rv5j1201	1818	10	(	(	-LRB-
cord-022561-rv5j1201	1818	11	also	also	RB
cord-022561-rv5j1201	1818	12	referred	refer	VBN
cord-022561-rv5j1201	1818	13	to	to	IN
cord-022561-rv5j1201	1818	14	as	as	IN
cord-022561-rv5j1201	1818	15	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	1818	16	nodules	nodule	NNS
cord-022561-rv5j1201	1818	17	)	)	-RRB-
cord-022561-rv5j1201	1818	18	(	(	-LRB-
cord-022561-rv5j1201	1818	19	see	see	VB
cord-022561-rv5j1201	1818	20	.	.	.
cord-022561-rv5j1201	1819	1	The	the	DT
cord-022561-rv5j1201	1819	2	follicles	follicle	NNS
cord-022561-rv5j1201	1819	3	are	be	VBP
cord-022561-rv5j1201	1819	4	designated	designate	VBN
cord-022561-rv5j1201	1819	5	as	as	IN
cord-022561-rv5j1201	1819	6	primary	primary	JJ
cord-022561-rv5j1201	1819	7	if	if	IN
cord-022561-rv5j1201	1819	8	they	-PRON-	PRP
cord-022561-rv5j1201	1819	9	consist	consist	VBP
cord-022561-rv5j1201	1819	10	mainly	mainly	RB
cord-022561-rv5j1201	1819	11	of	of	IN
cord-022561-rv5j1201	1819	12	small	small	JJ
cord-022561-rv5j1201	1819	13	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	1819	14	:	:	:
cord-022561-rv5j1201	1820	1	Mature	mature	JJ
cord-022561-rv5j1201	1820	2	naïve	naïve	JJ
cord-022561-rv5j1201	1820	3	B	b	NN
cord-022561-rv5j1201	1820	4	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	1820	5	expressing	express	VBG
cord-022561-rv5j1201	1820	6	receptors	receptor	NNS
cord-022561-rv5j1201	1820	7	for	for	IN
cord-022561-rv5j1201	1820	8	specific	specific	JJ
cord-022561-rv5j1201	1820	9	antigens	antigen	NNS
cord-022561-rv5j1201	1820	10	exit	exit	NN
cord-022561-rv5j1201	1820	11	the	the	DT
cord-022561-rv5j1201	1820	12	bone	bone	NN
cord-022561-rv5j1201	1820	13	marrow	marrow	NN
cord-022561-rv5j1201	1820	14	and	and	CC
cord-022561-rv5j1201	1820	15	circulate	circulate	VB
cord-022561-rv5j1201	1820	16	through	through	IN
cord-022561-rv5j1201	1820	17	the	the	DT
cord-022561-rv5j1201	1820	18	bloodstream	bloodstream	NN
cord-022561-rv5j1201	1820	19	,	,	,
cord-022561-rv5j1201	1820	20	lymphatic	lymphatic	JJ
cord-022561-rv5j1201	1820	21	vessels	vessel	NNS
cord-022561-rv5j1201	1820	22	,	,	,
cord-022561-rv5j1201	1820	23	and	and	CC
cord-022561-rv5j1201	1820	24	secondary	secondary	JJ
cord-022561-rv5j1201	1820	25	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	1820	26	tissues	tissue	NNS
cord-022561-rv5j1201	1820	27	.	.	.
cord-022561-rv5j1201	1821	1	On	on	IN
cord-022561-rv5j1201	1821	2	their	-PRON-	PRP$
cord-022561-rv5j1201	1821	3	arrival	arrival	NN
cord-022561-rv5j1201	1821	4	at	at	IN
cord-022561-rv5j1201	1821	5	lymph	lymph	NN
cord-022561-rv5j1201	1821	6	nodes	node	NNS
cord-022561-rv5j1201	1821	7	,	,	,
cord-022561-rv5j1201	1821	8	B	b	NN
cord-022561-rv5j1201	1821	9	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	1821	10	exit	exit	VBP
cord-022561-rv5j1201	1821	11	through	through	IN
cord-022561-rv5j1201	1821	12	HEVs	hev	NNS
cord-022561-rv5j1201	1821	13	in	in	IN
cord-022561-rv5j1201	1821	14	the	the	DT
cord-022561-rv5j1201	1821	15	paracortex	paracortex	NN
cord-022561-rv5j1201	1821	16	and	and	CC
cord-022561-rv5j1201	1821	17	home	home	NN
cord-022561-rv5j1201	1821	18	to	to	IN
cord-022561-rv5j1201	1821	19	a	a	DT
cord-022561-rv5j1201	1821	20	primary	primary	JJ
cord-022561-rv5j1201	1821	21	follicle	follicle	NN
cord-022561-rv5j1201	1821	22	(	(	-LRB-
cord-022561-rv5j1201	1821	23	which	which	WDT
cord-022561-rv5j1201	1821	24	also	also	RB
cord-022561-rv5j1201	1821	25	contains	contain	VBZ
cord-022561-rv5j1201	1821	26	follicular	follicular	JJ
cord-022561-rv5j1201	1821	27	DCs	dc	NNS
cord-022561-rv5j1201	1821	28	in	in	IN
cord-022561-rv5j1201	1821	29	addition	addition	NN
cord-022561-rv5j1201	1821	30	to	to	IN
cord-022561-rv5j1201	1821	31	the	the	DT
cord-022561-rv5j1201	1821	32	resting	rest	VBG
cord-022561-rv5j1201	1821	33	B	b	NN
cord-022561-rv5j1201	1821	34	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	1821	35	)	)	-RRB-
cord-022561-rv5j1201	1821	36	.	.	.
cord-022561-rv5j1201	1822	1	Lymphoid	lymphoid	JJ
cord-022561-rv5j1201	1822	2	follicles	follicle	NNS
cord-022561-rv5j1201	1822	3	with	with	IN
cord-022561-rv5j1201	1822	4	germinal	germinal	JJ
cord-022561-rv5j1201	1822	5	centers	center	NNS
cord-022561-rv5j1201	1822	6	are	be	VBP
cord-022561-rv5j1201	1822	7	designated	designate	VBN
cord-022561-rv5j1201	1822	8	as	as	IN
cord-022561-rv5j1201	1822	9	secondary	secondary	JJ
cord-022561-rv5j1201	1822	10	follicles	follicle	NNS
cord-022561-rv5j1201	1822	11	:	:	:
cord-022561-rv5j1201	1822	12	B	b	NN
cord-022561-rv5j1201	1822	13	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	1822	14	that	that	WDT
cord-022561-rv5j1201	1822	15	recognize	recognize	VBP
cord-022561-rv5j1201	1822	16	the	the	DT
cord-022561-rv5j1201	1822	17	antigen	antigen	NN
cord-022561-rv5j1201	1822	18	for	for	IN
cord-022561-rv5j1201	1822	19	which	which	WDT
cord-022561-rv5j1201	1822	20	they	-PRON-	PRP
cord-022561-rv5j1201	1822	21	are	be	VBP
cord-022561-rv5j1201	1822	22	expressing	express	VBG
cord-022561-rv5j1201	1822	23	receptors	receptor	NNS
cord-022561-rv5j1201	1822	24	are	be	VBP
cord-022561-rv5j1201	1822	25	activated	activate	VBN
cord-022561-rv5j1201	1822	26	and	and	CC
cord-022561-rv5j1201	1822	27	proliferate	proliferate	VB
cord-022561-rv5j1201	1822	28	to	to	TO
cord-022561-rv5j1201	1822	29	form	form	VB
cord-022561-rv5j1201	1822	30	the	the	DT
cord-022561-rv5j1201	1822	31	secondary	secondary	JJ
cord-022561-rv5j1201	1822	32	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	1822	33	follicles	follicle	NNS
cord-022561-rv5j1201	1822	34	characterized	characterize	VBN
cord-022561-rv5j1201	1822	35	by	by	IN
cord-022561-rv5j1201	1822	36	prominent	prominent	JJ
cord-022561-rv5j1201	1822	37	germinal	germinal	JJ
cord-022561-rv5j1201	1822	38	centers	center	NNS
cord-022561-rv5j1201	1822	39	.	.	.
cord-022561-rv5j1201	1823	1	Germinal	germinal	JJ
cord-022561-rv5j1201	1823	2	centers	center	NNS
cord-022561-rv5j1201	1823	3	are	be	VBP
cord-022561-rv5j1201	1823	4	areas	area	NNS
cord-022561-rv5j1201	1823	5	with	with	IN
cord-022561-rv5j1201	1823	6	a	a	DT
cord-022561-rv5j1201	1823	7	specialized	specialized	JJ
cord-022561-rv5j1201	1823	8	•	•	NNP
cord-022561-rv5j1201	1823	9	Stroma	Stroma	NNP
cord-022561-rv5j1201	1823	10	-	-	HYPH
cord-022561-rv5j1201	1823	11	Capsule	Capsule	NNP
cord-022561-rv5j1201	1823	12	,	,	,
cord-022561-rv5j1201	1823	13	trabeculae	trabeculae	NNP
cord-022561-rv5j1201	1823	14	,	,	,
cord-022561-rv5j1201	1823	15	and	and	CC
cord-022561-rv5j1201	1823	16	reticulum	reticulum	NN
cord-022561-rv5j1201	1823	17	•	•	NNP
cord-022561-rv5j1201	1823	18	Cortex-"Superficial	cortex-"superficial	NN
cord-022561-rv5j1201	1823	19	"	"	''
cord-022561-rv5j1201	1823	20	or	or	CC
cord-022561-rv5j1201	1823	21	"	"	``
cord-022561-rv5j1201	1823	22	outer	outer	JJ
cord-022561-rv5j1201	1823	23	"	"	''
cord-022561-rv5j1201	1823	24	cortex	cortex	NN
cord-022561-rv5j1201	1823	25	(	(	-LRB-
cord-022561-rv5j1201	1823	26	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	1823	27	follicles	follicle	NNS
cord-022561-rv5j1201	1823	28	,	,	,
cord-022561-rv5j1201	1823	29	B	b	NN
cord-022561-rv5j1201	1823	30	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	1823	31	)	)	-RRB-
cord-022561-rv5j1201	1824	1	•	•	NNP
cord-022561-rv5j1201	1825	1	Paracortex-"Deep	Paracortex-"Deep	NNP
cord-022561-rv5j1201	1825	2	"	"	''
cord-022561-rv5j1201	1825	3	or	or	CC
cord-022561-rv5j1201	1825	4	"	"	``
cord-022561-rv5j1201	1825	5	inner	inner	JJ
cord-022561-rv5j1201	1825	6	"	"	''
cord-022561-rv5j1201	1825	7	cortex	cortex	NN
cord-022561-rv5j1201	1825	8	(	(	-LRB-
cord-022561-rv5j1201	1825	9	T	t	NN
cord-022561-rv5j1201	1825	10	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	1825	11	)	)	-RRB-
cord-022561-rv5j1201	1826	1	•	•	NNP
cord-022561-rv5j1201	1826	2	Medulla	Medulla	NNP
cord-022561-rv5j1201	1826	3	-	-	HYPH
cord-022561-rv5j1201	1826	4	Medullary	Medullary	NNP
cord-022561-rv5j1201	1826	5	sinuses	sinus	NNS
cord-022561-rv5j1201	1826	6	and	and	CC
cord-022561-rv5j1201	1826	7	medullary	medullary	JJ
cord-022561-rv5j1201	1826	8	cords	cord	NNS
cord-022561-rv5j1201	1827	1	•	•	NNP
cord-022561-rv5j1201	1828	1	Blood	blood	NN
cord-022561-rv5j1201	1828	2	vessels	vessel	NNS
cord-022561-rv5j1201	1828	3	-	-	:
cord-022561-rv5j1201	1828	4	Arteries	artery	NNS
cord-022561-rv5j1201	1828	5	,	,	,
cord-022561-rv5j1201	1828	6	arterioles	arteriole	NNS
cord-022561-rv5j1201	1828	7	,	,	,
cord-022561-rv5j1201	1828	8	high	high	JJ
cord-022561-rv5j1201	1828	9	endothelial	endothelial	JJ
cord-022561-rv5j1201	1828	10	venules	venule	NNS
cord-022561-rv5j1201	1828	11	(	(	-LRB-
cord-022561-rv5j1201	1828	12	HEVs	hev	NNS
cord-022561-rv5j1201	1828	13	)	)	-RRB-
cord-022561-rv5j1201	1828	14	,	,	,
cord-022561-rv5j1201	1828	15	efferent	efferent	JJ
cord-022561-rv5j1201	1828	16	veins	vein	NNS
cord-022561-rv5j1201	1829	1	•	•	NNP
cord-022561-rv5j1201	1830	1	Lymphatic	lymphatic	JJ
cord-022561-rv5j1201	1830	2	vessels	vessel	NNS
cord-022561-rv5j1201	1830	3	-	-	:
cord-022561-rv5j1201	1830	4	Lymphatic	lymphatic	JJ
cord-022561-rv5j1201	1830	5	afferent	afferent	NN
cord-022561-rv5j1201	1830	6	and	and	CC
cord-022561-rv5j1201	1830	7	efferent	efferent	JJ
cord-022561-rv5j1201	1830	8	vessels	vessel	NNS
cord-022561-rv5j1201	1830	9	;	;	,
cord-022561-rv5j1201	1830	10	lymphatic	lymphatic	JJ
cord-022561-rv5j1201	1830	11	sinuses	sinus	NNS
cord-022561-rv5j1201	1830	12	(	(	-LRB-
cord-022561-rv5j1201	1830	13	subcapsular	subcapsular	JJ
cord-022561-rv5j1201	1830	14	,	,	,
cord-022561-rv5j1201	1830	15	trabecular	trabecular	NN
cord-022561-rv5j1201	1830	16	,	,	,
cord-022561-rv5j1201	1830	17	and	and	CC
cord-022561-rv5j1201	1830	18	medullary	medullary	NN
cord-022561-rv5j1201	1830	19	)	)	-RRB-
cord-022561-rv5j1201	1831	1	•	•	NNP
cord-022561-rv5j1201	1831	2	Monocyte	Monocyte	NNP
cord-022561-rv5j1201	1831	3	-	-	HYPH
cord-022561-rv5j1201	1831	4	macrophage	macrophage	NN
cord-022561-rv5j1201	1831	5	system	system	NN
cord-022561-rv5j1201	1831	6	-	-	:
cord-022561-rv5j1201	1831	7	Sinus	sinus	NN
cord-022561-rv5j1201	1831	8	histiocytes	histiocyte	NNS
cord-022561-rv5j1201	1831	9	Stroma	Stroma	NNP
cord-022561-rv5j1201	1831	10	.	.	.
cord-022561-rv5j1201	1832	1	The	the	DT
cord-022561-rv5j1201	1832	2	lymph	lymph	NN
cord-022561-rv5j1201	1832	3	node	node	NN
cord-022561-rv5j1201	1832	4	is	be	VBZ
cord-022561-rv5j1201	1832	5	enclosed	enclose	VBN
cord-022561-rv5j1201	1832	6	by	by	IN
cord-022561-rv5j1201	1832	7	a	a	DT
cord-022561-rv5j1201	1832	8	fibrous	fibrous	JJ
cord-022561-rv5j1201	1832	9	capsule	capsule	NN
cord-022561-rv5j1201	1832	10	penetrated	penetrate	VBN
cord-022561-rv5j1201	1832	11	by	by	IN
cord-022561-rv5j1201	1832	12	multiple	multiple	JJ
cord-022561-rv5j1201	1832	13	afferent	afferent	JJ
cord-022561-rv5j1201	1832	14	lymphatic	lymphatic	NN
cord-022561-rv5j1201	1832	15	vessels	vessel	NNS
cord-022561-rv5j1201	1832	16	,	,	,
cord-022561-rv5j1201	1832	17	which	which	WDT
cord-022561-rv5j1201	1832	18	empty	empty	JJ
cord-022561-rv5j1201	1832	19	into	into	IN
cord-022561-rv5j1201	1832	20	the	the	DT
cord-022561-rv5j1201	1832	21	subcapsular	subcapsular	JJ
cord-022561-rv5j1201	1832	22	sinus	sinus	NNP
cord-022561-rv5j1201	1832	23	(	(	-LRB-
cord-022561-rv5j1201	1832	24	see	see	VB
cord-022561-rv5j1201	1832	25	also	also	RB
cord-022561-rv5j1201	1832	26	.	.	.
cord-022561-rv5j1201	1833	1	At	at	IN
cord-022561-rv5j1201	1833	2	the	the	DT
cord-022561-rv5j1201	1833	3	hilus	hilus	NN
cord-022561-rv5j1201	1833	4	,	,	,
cord-022561-rv5j1201	1833	5	efferent	efferent	JJ
cord-022561-rv5j1201	1833	6	lymphatic	lymphatic	JJ
cord-022561-rv5j1201	1833	7	vessels	vessel	NNS
cord-022561-rv5j1201	1833	8	and	and	CC
cord-022561-rv5j1201	1833	9	veins	vein	NNS
cord-022561-rv5j1201	1833	10	exit	exit	NN
cord-022561-rv5j1201	1833	11	,	,	,
cord-022561-rv5j1201	1833	12	and	and	CC
cord-022561-rv5j1201	1833	13	arteries	artery	NNS
cord-022561-rv5j1201	1833	14	enter	enter	VBP
cord-022561-rv5j1201	1833	15	the	the	DT
cord-022561-rv5j1201	1833	16	node	node	NN
cord-022561-rv5j1201	1833	17	.	.	.
cord-022561-rv5j1201	1834	1	Fibrous	fibrous	JJ
cord-022561-rv5j1201	1834	2	trabeculae	trabecula	NNS
cord-022561-rv5j1201	1834	3	extend	extend	VBP
cord-022561-rv5j1201	1834	4	from	from	IN
cord-022561-rv5j1201	1834	5	the	the	DT
cord-022561-rv5j1201	1834	6	capsule	capsule	NN
cord-022561-rv5j1201	1834	7	into	into	IN
cord-022561-rv5j1201	1834	8	the	the	DT
cord-022561-rv5j1201	1834	9	parenchyma	parenchyma	NN
cord-022561-rv5j1201	1834	10	to	to	TO
cord-022561-rv5j1201	1834	11	provide	provide	VB
cord-022561-rv5j1201	1834	12	support	support	NN
cord-022561-rv5j1201	1834	13	to	to	IN
cord-022561-rv5j1201	1834	14	the	the	DT
cord-022561-rv5j1201	1834	15	node	node	NN
cord-022561-rv5j1201	1834	16	and	and	CC
cord-022561-rv5j1201	1834	17	to	to	IN
cord-022561-rv5j1201	1834	18	house	house	NN
cord-022561-rv5j1201	1834	19	vessels	vessel	NNS
cord-022561-rv5j1201	1834	20	and	and	CC
cord-022561-rv5j1201	1834	21	nerves	nerve	NNS
cord-022561-rv5j1201	1834	22	.	.	.
cord-022561-rv5j1201	1835	1	The	the	DT
cord-022561-rv5j1201	1835	2	lymph	lymph	NN
cord-022561-rv5j1201	1835	3	node	node	NN
cord-022561-rv5j1201	1835	4	is	be	VBZ
cord-022561-rv5j1201	1835	5	also	also	RB
cord-022561-rv5j1201	1835	6	supported	support	VBN
cord-022561-rv5j1201	1835	7	by	by	IN
cord-022561-rv5j1201	1835	8	a	a	DT
cord-022561-rv5j1201	1835	9	meshwork	meshwork	NN
cord-022561-rv5j1201	1835	10	of	of	IN
cord-022561-rv5j1201	1835	11	Medulla	Medulla	NNP
cord-022561-rv5j1201	1835	12	.	.	.
cord-022561-rv5j1201	1836	1	The	the	DT
cord-022561-rv5j1201	1836	2	medulla	medulla	NN
cord-022561-rv5j1201	1836	3	is	be	VBZ
cord-022561-rv5j1201	1836	4	composed	compose	VBN
cord-022561-rv5j1201	1836	5	of	of	IN
cord-022561-rv5j1201	1836	6	medullary	medullary	JJ
cord-022561-rv5j1201	1836	7	cords	cord	NNS
cord-022561-rv5j1201	1836	8	and	and	CC
cord-022561-rv5j1201	1836	9	medullary	medullary	JJ
cord-022561-rv5j1201	1836	10	sinuses	sinus	NNS
cord-022561-rv5j1201	1836	11	(	(	-LRB-
cord-022561-rv5j1201	1836	12	see	see	VB
cord-022561-rv5j1201	1836	13	.	.	.
cord-022561-rv5j1201	1837	1	The	the	DT
cord-022561-rv5j1201	1837	2	medullary	medullary	JJ
cord-022561-rv5j1201	1837	3	cords	cord	NNS
cord-022561-rv5j1201	1837	4	contain	contain	VBP
cord-022561-rv5j1201	1837	5	macrophages	macrophage	NNS
cord-022561-rv5j1201	1837	6	,	,	,
cord-022561-rv5j1201	1837	7	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	1837	8	,	,	,
cord-022561-rv5j1201	1837	9	and	and	CC
cord-022561-rv5j1201	1837	10	plasma	plasma	NN
cord-022561-rv5j1201	1837	11	cells	cell	NNS
cord-022561-rv5j1201	1837	12	.	.	.
cord-022561-rv5j1201	1838	1	In	in	IN
cord-022561-rv5j1201	1838	2	a	a	DT
cord-022561-rv5j1201	1838	3	stimulated	stimulated	JJ
cord-022561-rv5j1201	1838	4	node	node	NN
cord-022561-rv5j1201	1838	5	the	the	DT
cord-022561-rv5j1201	1838	6	cords	cord	NNS
cord-022561-rv5j1201	1838	7	become	become	VBP
cord-022561-rv5j1201	1838	8	filled	fill	VBN
cord-022561-rv5j1201	1838	9	with	with	IN
cord-022561-rv5j1201	1838	10	antibody	antibody	NN
cord-022561-rv5j1201	1838	11	-	-	HYPH
cord-022561-rv5j1201	1838	12	secreting	secrete	VBG
cord-022561-rv5j1201	1838	13	plasma	plasma	NN
cord-022561-rv5j1201	1838	14	cells	cell	NNS
cord-022561-rv5j1201	1838	15	.	.	.
cord-022561-rv5j1201	1839	1	The	the	DT
cord-022561-rv5j1201	1839	2	medullary	medullary	JJ
cord-022561-rv5j1201	1839	3	sinuses	sinus	NNS
cord-022561-rv5j1201	1839	4	are	be	VBP
cord-022561-rv5j1201	1839	5	lined	line	VBN
cord-022561-rv5j1201	1839	6	by	by	IN
cord-022561-rv5j1201	1839	7	fibroblastic	fibroblastic	JJ
cord-022561-rv5j1201	1839	8	reticular	reticular	JJ
cord-022561-rv5j1201	1839	9	cells	cell	NNS
cord-022561-rv5j1201	1839	10	and	and	CC
cord-022561-rv5j1201	1839	11	contain	contain	VBP
cord-022561-rv5j1201	1839	12	macrophages	macrophage	NNS
cord-022561-rv5j1201	1839	13	(	(	-LRB-
cord-022561-rv5j1201	1839	14	"	"	``
cord-022561-rv5j1201	1839	15	sinus	sinus	NNP
cord-022561-rv5j1201	1839	16	histiocytes	histiocyte	NNS
cord-022561-rv5j1201	1839	17	"	"	''
cord-022561-rv5j1201	1839	18	)	)	-RRB-
cord-022561-rv5j1201	1839	19	,	,	,
cord-022561-rv5j1201	1839	20	which	which	WDT
cord-022561-rv5j1201	1839	21	cling	cling	VBP
cord-022561-rv5j1201	1839	22	to	to	IN
cord-022561-rv5j1201	1839	23	reticular	reticular	JJ
cord-022561-rv5j1201	1839	24	fibers	fiber	NNS
cord-022561-rv5j1201	1839	25	crossing	cross	VBG
cord-022561-rv5j1201	1839	26	the	the	DT
cord-022561-rv5j1201	1839	27	lumen	lumen	NN
cord-022561-rv5j1201	1839	28	of	of	IN
cord-022561-rv5j1201	1839	29	the	the	DT
cord-022561-rv5j1201	1839	30	sinus	sinus	NN
cord-022561-rv5j1201	1839	31	.	.	.
cord-022561-rv5j1201	1840	1	These	these	DT
cord-022561-rv5j1201	1840	2	macrophages	macrophage	NNS
cord-022561-rv5j1201	1840	3	phagocytize	phagocytize	VBP
cord-022561-rv5j1201	1840	4	foreign	foreign	JJ
cord-022561-rv5j1201	1840	5	material	material	NN
cord-022561-rv5j1201	1840	6	,	,	,
cord-022561-rv5j1201	1840	7	cellular	cellular	JJ
cord-022561-rv5j1201	1840	8	debris	debris	NN
cord-022561-rv5j1201	1840	9	,	,	,
cord-022561-rv5j1201	1840	10	and	and	CC
cord-022561-rv5j1201	1840	11	bacteria	bacteria	NNS
cord-022561-rv5j1201	1840	12	from	from	IN
cord-022561-rv5j1201	1840	13	the	the	DT
cord-022561-rv5j1201	1840	14	incoming	incoming	JJ
cord-022561-rv5j1201	1840	15	lymph	lymph	NN
cord-022561-rv5j1201	1840	16	.	.	.
cord-022561-rv5j1201	1841	1	Vasculature	Vasculature	NNP
cord-022561-rv5j1201	1841	2	:	:	:
cord-022561-rv5j1201	1841	3	Blood	blood	NN
cord-022561-rv5j1201	1841	4	Vessels	vessel	NNS
cord-022561-rv5j1201	1841	5	,	,	,
cord-022561-rv5j1201	1841	6	Lymphatic	lymphatic	JJ
cord-022561-rv5j1201	1841	7	Vessels	vessel	NNS
cord-022561-rv5j1201	1841	8	,	,	,
cord-022561-rv5j1201	1841	9	and	and	CC
cord-022561-rv5j1201	1841	10	Lymphatic	lymphatic	JJ
cord-022561-rv5j1201	1841	11	Sinuses	sinus	NNS
cord-022561-rv5j1201	1841	12	.	.	.
cord-022561-rv5j1201	1842	1	The	the	DT
cord-022561-rv5j1201	1842	2	blood	blood	NN
cord-022561-rv5j1201	1842	3	vessels	vessel	NNS
cord-022561-rv5j1201	1842	4	of	of	IN
cord-022561-rv5j1201	1842	5	the	the	DT
cord-022561-rv5j1201	1842	6	lymph	lymph	NN
cord-022561-rv5j1201	1842	7	node	node	NN
cord-022561-rv5j1201	1842	8	include	include	VBP
cord-022561-rv5j1201	1842	9	arteries	artery	NNS
cord-022561-rv5j1201	1842	10	,	,	,
cord-022561-rv5j1201	1842	11	arterioles	arteriole	NNS
cord-022561-rv5j1201	1842	12	,	,	,
cord-022561-rv5j1201	1842	13	veins	vein	NNS
cord-022561-rv5j1201	1842	14	,	,	,
cord-022561-rv5j1201	1842	15	and	and	CC
cord-022561-rv5j1201	1842	16	postcapillary	postcapillary	NNP
cord-022561-rv5j1201	1842	17	venules	venules	NNPS
cord-022561-rv5j1201	1842	18	(	(	-LRB-
cord-022561-rv5j1201	1842	19	HEVs	hev	NNS
cord-022561-rv5j1201	1842	20	)	)	-RRB-
cord-022561-rv5j1201	1842	21	lined	line	VBN
cord-022561-rv5j1201	1842	22	by	by	IN
cord-022561-rv5j1201	1842	23	specialized	specialized	JJ
cord-022561-rv5j1201	1842	24	cuboidal	cuboidal	JJ
cord-022561-rv5j1201	1842	25	endothelium	endothelium	NN
cord-022561-rv5j1201	1842	26	(	(	-LRB-
cord-022561-rv5j1201	1842	27	see	see	VB
cord-022561-rv5j1201	1842	28	Figs	fig	NNS
cord-022561-rv5j1201	1842	29	.	.	.
cord-022561-rv5j1201	1843	1	13	13	CD
cord-022561-rv5j1201	1843	2	-	-	SYM
cord-022561-rv5j1201	1843	3	45	45	CD
cord-022561-rv5j1201	1843	4	and	and	CC
cord-022561-rv5j1201	1843	5	13	13	CD
cord-022561-rv5j1201	1843	6	-	-	SYM
cord-022561-rv5j1201	1843	7	46	46	CD
cord-022561-rv5j1201	1843	8	)	)	-RRB-
cord-022561-rv5j1201	1843	9	.	.	.
cord-022561-rv5j1201	1844	1	microenvironment	microenvironment	NN
cord-022561-rv5j1201	1844	2	that	that	WDT
cord-022561-rv5j1201	1844	3	support	support	VBP
cord-022561-rv5j1201	1844	4	the	the	DT
cord-022561-rv5j1201	1844	5	proliferation	proliferation	NN
cord-022561-rv5j1201	1844	6	and	and	CC
cord-022561-rv5j1201	1844	7	further	further	JJ
cord-022561-rv5j1201	1844	8	development	development	NN
cord-022561-rv5j1201	1844	9	of	of	IN
cord-022561-rv5j1201	1844	10	B	b	NN
cord-022561-rv5j1201	1844	11	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	1844	12	to	to	TO
cord-022561-rv5j1201	1844	13	increase	increase	VB
cord-022561-rv5j1201	1844	14	their	-PRON-	PRP$
cord-022561-rv5j1201	1844	15	antigen	antigen	NN
cord-022561-rv5j1201	1844	16	and	and	CC
cord-022561-rv5j1201	1844	17	functional	functional	JJ
cord-022561-rv5j1201	1844	18	capacity	capacity	NN
cord-022561-rv5j1201	1844	19	(	(	-LRB-
cord-022561-rv5j1201	1844	20	see	see	VB
cord-022561-rv5j1201	1845	1	Lymphoid	lymphoid	JJ
cord-022561-rv5j1201	1845	2	/	/	SYM
cord-022561-rv5j1201	1845	3	Lymphatic	Lymphatic	NNP
cord-022561-rv5j1201	1845	4	System	System	NNP
cord-022561-rv5j1201	1845	5	,	,	,
cord-022561-rv5j1201	1845	6	Lymph	lymph	NN
cord-022561-rv5j1201	1845	7	Nodes	node	NNS
cord-022561-rv5j1201	1845	8	,	,	,
cord-022561-rv5j1201	1845	9	Function	function	NN
cord-022561-rv5j1201	1845	10	)	)	-RRB-
cord-022561-rv5j1201	1845	11	.	.	.
cord-022561-rv5j1201	1846	1	The	the	DT
cord-022561-rv5j1201	1846	2	mantle	mantle	NN
cord-022561-rv5j1201	1846	3	cell	cell	NN
cord-022561-rv5j1201	1846	4	zone	zone	NN
cord-022561-rv5j1201	1846	5	surrounds	surround	VBZ
cord-022561-rv5j1201	1846	6	the	the	DT
cord-022561-rv5j1201	1846	7	germinal	germinal	JJ
cord-022561-rv5j1201	1846	8	center	center	NN
cord-022561-rv5j1201	1846	9	and	and	CC
cord-022561-rv5j1201	1846	10	consists	consist	VBZ
cord-022561-rv5j1201	1846	11	of	of	IN
cord-022561-rv5j1201	1846	12	small	small	JJ
cord-022561-rv5j1201	1846	13	inactive	inactive	JJ
cord-022561-rv5j1201	1846	14	mature	mature	JJ
cord-022561-rv5j1201	1846	15	naïve	naïve	JJ
cord-022561-rv5j1201	1846	16	B	b	NN
cord-022561-rv5j1201	1846	17	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	1846	18	and	and	CC
cord-022561-rv5j1201	1846	19	a	a	DT
cord-022561-rv5j1201	1846	20	smaller	small	JJR
cord-022561-rv5j1201	1846	21	population	population	NN
cord-022561-rv5j1201	1846	22	of	of	IN
cord-022561-rv5j1201	1846	23	T	T	NNP
cord-022561-rv5j1201	1846	24	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	1846	25	(	(	-LRB-
cord-022561-rv5j1201	1846	26	approximately	approximately	RB
cord-022561-rv5j1201	1846	27	10	10	CD
cord-022561-rv5j1201	1846	28	%	%	NN
cord-022561-rv5j1201	1846	29	)	)	-RRB-
cord-022561-rv5j1201	1846	30	.	.	.
cord-022561-rv5j1201	1847	1	Paracortex	Paracortex	NNP
cord-022561-rv5j1201	1847	2	.	.	.
cord-022561-rv5j1201	1848	1	The	the	DT
cord-022561-rv5j1201	1848	2	diffuse	diffuse	JJ
cord-022561-rv5j1201	1848	3	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	1848	4	tissue	tissue	NN
cord-022561-rv5j1201	1848	5	of	of	IN
cord-022561-rv5j1201	1848	6	the	the	DT
cord-022561-rv5j1201	1848	7	paracortex	paracortex	NN
cord-022561-rv5j1201	1848	8	(	(	-LRB-
cord-022561-rv5j1201	1848	9	also	also	RB
cord-022561-rv5j1201	1848	10	referred	refer	VBN
cord-022561-rv5j1201	1848	11	to	to	IN
cord-022561-rv5j1201	1848	12	as	as	IN
cord-022561-rv5j1201	1848	13	the	the	DT
cord-022561-rv5j1201	1848	14	deep	deep	JJ
cord-022561-rv5j1201	1848	15	or	or	CC
cord-022561-rv5j1201	1848	16	inner	inner	JJ
cord-022561-rv5j1201	1848	17	cortex	cortex	NN
cord-022561-rv5j1201	1848	18	)	)	-RRB-
cord-022561-rv5j1201	1848	19	consists	consist	VBZ
cord-022561-rv5j1201	1848	20	mainly	mainly	RB
cord-022561-rv5j1201	1848	21	of	of	IN
cord-022561-rv5j1201	1848	22	T	t	NN
cord-022561-rv5j1201	1848	23	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	1848	24	,	,	,
cord-022561-rv5j1201	1848	25	as	as	RB
cord-022561-rv5j1201	1848	26	well	well	RB
cord-022561-rv5j1201	1848	27	as	as	IN
cord-022561-rv5j1201	1848	28	macrophages	macrophage	NNS
cord-022561-rv5j1201	1848	29	and	and	CC
cord-022561-rv5j1201	1848	30	DCs	dc	NNS
cord-022561-rv5j1201	1848	31	(	(	-LRB-
cord-022561-rv5j1201	1848	32	see	see	VB
cord-022561-rv5j1201	1848	33	.	.	.
cord-022561-rv5j1201	1849	1	This	this	DT
cord-022561-rv5j1201	1849	2	region	region	NN
cord-022561-rv5j1201	1849	3	contains	contain	VBZ
cord-022561-rv5j1201	1849	4	the	the	DT
cord-022561-rv5j1201	1849	5	HEVs	hev	NNS
cord-022561-rv5j1201	1849	6	through	through	IN
cord-022561-rv5j1201	1849	7	which	which	WDT
cord-022561-rv5j1201	1849	8	B	b	NN
cord-022561-rv5j1201	1849	9	and	and	CC
cord-022561-rv5j1201	1849	10	T	t	NN
cord-022561-rv5j1201	1849	11	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	1849	12	migrate	migrate	VBP
cord-022561-rv5j1201	1849	13	from	from	IN
cord-022561-rv5j1201	1849	14	the	the	DT
cord-022561-rv5j1201	1849	15	blood	blood	NN
cord-022561-rv5j1201	1849	16	into	into	IN
cord-022561-rv5j1201	1849	17	the	the	DT
cord-022561-rv5j1201	1849	18	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	1849	19	follicles	follicle	NNS
cord-022561-rv5j1201	1849	20	and	and	CC
cord-022561-rv5j1201	1849	21	paracortex	paracortex	NN
cord-022561-rv5j1201	1849	22	,	,	,
cord-022561-rv5j1201	1849	23	respectively	respectively	RB
cord-022561-rv5j1201	1849	24	.	.	.
cord-022561-rv5j1201	1850	1	T	T	NNP
cord-022561-rv5j1201	1850	2	and	and	CC
cord-022561-rv5j1201	1850	3	B	b	NN
cord-022561-rv5j1201	1850	4	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	1850	5	may	may	MD
cord-022561-rv5j1201	1850	6	also	also	RB
cord-022561-rv5j1201	1850	7	enter	enter	VB
cord-022561-rv5j1201	1850	8	the	the	DT
cord-022561-rv5j1201	1850	9	lymph	lymph	NN
cord-022561-rv5j1201	1850	10	node	node	NN
cord-022561-rv5j1201	1850	11	via	via	IN
cord-022561-rv5j1201	1850	12	the	the	DT
cord-022561-rv5j1201	1850	13	lymphatic	lymphatic	JJ
cord-022561-rv5j1201	1850	14	vessels	vessel	NNS
cord-022561-rv5j1201	1850	15	.	.	.
cord-022561-rv5j1201	1851	1	and	and	CC
cord-022561-rv5j1201	1851	2	larger	large	JJR
cord-022561-rv5j1201	1851	3	molecules	molecule	NNS
cord-022561-rv5j1201	1851	4	,	,	,
cord-022561-rv5j1201	1851	5	small	small	JJ
cord-022561-rv5j1201	1851	6	molecules	molecule	NNS
cord-022561-rv5j1201	1851	7	and	and	CC
cord-022561-rv5j1201	1851	8	free	free	JJ
cord-022561-rv5j1201	1851	9	antigens	antigen	NNS
cord-022561-rv5j1201	1851	10	,	,	,
cord-022561-rv5j1201	1851	11	and	and	CC
cord-022561-rv5j1201	1851	12	antigen	antigen	NN
cord-022561-rv5j1201	1851	13	within	within	IN
cord-022561-rv5j1201	1851	14	DCs	dc	NNS
cord-022561-rv5j1201	1851	15	.	.	.
cord-022561-rv5j1201	1852	1	It	-PRON-	PRP
cord-022561-rv5j1201	1852	2	is	be	VBZ
cord-022561-rv5j1201	1852	3	helpful	helpful	JJ
cord-022561-rv5j1201	1852	4	to	to	TO
cord-022561-rv5j1201	1852	5	consider	consider	VB
cord-022561-rv5j1201	1852	6	the	the	DT
cord-022561-rv5j1201	1852	7	paths	path	NNS
cord-022561-rv5j1201	1852	8	taken	take	VBN
cord-022561-rv5j1201	1852	9	by	by	IN
cord-022561-rv5j1201	1852	10	particles	particle	NNS
cord-022561-rv5j1201	1852	11	,	,	,
cord-022561-rv5j1201	1852	12	molecules	molecule	NNS
cord-022561-rv5j1201	1852	13	,	,	,
cord-022561-rv5j1201	1852	14	antigens	antigen	NNS
cord-022561-rv5j1201	1852	15	,	,	,
cord-022561-rv5j1201	1852	16	and	and	CC
cord-022561-rv5j1201	1852	17	cells	cell	NNS
cord-022561-rv5j1201	1852	18	arriving	arrive	VBG
cord-022561-rv5j1201	1852	19	at	at	IN
cord-022561-rv5j1201	1852	20	a	a	DT
cord-022561-rv5j1201	1852	21	lymph	lymph	NN
cord-022561-rv5j1201	1852	22	node	node	NN
cord-022561-rv5j1201	1852	23	.	.	.
cord-022561-rv5j1201	1853	1	The	the	DT
cord-022561-rv5j1201	1853	2	following	following	JJ
cord-022561-rv5j1201	1853	3	account	account	NN
cord-022561-rv5j1201	1853	4	describes	describe	VBZ
cord-022561-rv5j1201	1853	5	the	the	DT
cord-022561-rv5j1201	1853	6	journey	journey	NN
cord-022561-rv5j1201	1853	7	of	of	IN
cord-022561-rv5j1201	1853	8	an	an	DT
cord-022561-rv5j1201	1853	9	antigen	antigen	NN
cord-022561-rv5j1201	1853	10	as	as	IN
cord-022561-rv5j1201	1853	11	it	-PRON-	PRP
cord-022561-rv5j1201	1853	12	enters	enter	VBZ
cord-022561-rv5j1201	1853	13	a	a	DT
cord-022561-rv5j1201	1853	14	lymph	lymph	NN
cord-022561-rv5j1201	1853	15	node	node	NN
cord-022561-rv5j1201	1853	16	to	to	TO
cord-022561-rv5j1201	1853	17	trigger	trigger	VB
cord-022561-rv5j1201	1853	18	an	an	DT
cord-022561-rv5j1201	1853	19	immune	immune	JJ
cord-022561-rv5j1201	1853	20	response	response	NN
cord-022561-rv5j1201	1853	21	.	.	.
cord-022561-rv5j1201	1854	1	Antigen	antigen	NN
cord-022561-rv5j1201	1854	2	in	in	IN
cord-022561-rv5j1201	1854	3	the	the	DT
cord-022561-rv5j1201	1854	4	lymph	lymph	NN
cord-022561-rv5j1201	1854	5	arriving	arrive	VBG
cord-022561-rv5j1201	1854	6	in	in	IN
cord-022561-rv5j1201	1854	7	the	the	DT
cord-022561-rv5j1201	1854	8	afferent	afferent	JJ
cord-022561-rv5j1201	1854	9	lymphatic	lymphatic	NN
cord-022561-rv5j1201	1854	10	vessels	vessel	NNS
cord-022561-rv5j1201	1854	11	empties	empty	VBZ
cord-022561-rv5j1201	1854	12	into	into	IN
cord-022561-rv5j1201	1854	13	the	the	DT
cord-022561-rv5j1201	1854	14	subcapsular	subcapsular	JJ
cord-022561-rv5j1201	1854	15	sinus	sinus	NNP
cord-022561-rv5j1201	1854	16	.	.	.
cord-022561-rv5j1201	1855	1	Hydrostatic	hydrostatic	JJ
cord-022561-rv5j1201	1855	2	pressure	pressure	NN
cord-022561-rv5j1201	1855	3	here	here	RB
cord-022561-rv5j1201	1855	4	is	be	VBZ
cord-022561-rv5j1201	1855	5	low	low	JJ
cord-022561-rv5j1201	1855	6	,	,	,
cord-022561-rv5j1201	1855	7	and	and	CC
cord-022561-rv5j1201	1855	8	reticular	reticular	JJ
cord-022561-rv5j1201	1855	9	fibers	fiber	NNS
cord-022561-rv5j1201	1855	10	crossing	cross	VBG
cord-022561-rv5j1201	1855	11	the	the	DT
cord-022561-rv5j1201	1855	12	sinus	sinus	NN
cord-022561-rv5j1201	1855	13	impede	impede	VB
cord-022561-rv5j1201	1855	14	flow	flow	NN
cord-022561-rv5j1201	1855	15	,	,	,
cord-022561-rv5j1201	1855	16	and	and	CC
cord-022561-rv5j1201	1855	17	thus	thus	RB
cord-022561-rv5j1201	1855	18	particles	particle	NNS
cord-022561-rv5j1201	1855	19	tend	tend	VBP
cord-022561-rv5j1201	1855	20	to	to	TO
cord-022561-rv5j1201	1855	21	settle	settle	VB
cord-022561-rv5j1201	1855	22	,	,	,
cord-022561-rv5j1201	1855	23	which	which	WDT
cord-022561-rv5j1201	1855	24	facilitates	facilitate	VBZ
cord-022561-rv5j1201	1855	25	phagocytosis	phagocytosis	NN
cord-022561-rv5j1201	1855	26	by	by	IN
cord-022561-rv5j1201	1855	27	the	the	DT
cord-022561-rv5j1201	1855	28	sinus	sinus	NN
cord-022561-rv5j1201	1855	29	macrophages	macrophage	NNS
cord-022561-rv5j1201	1855	30	.	.	.
cord-022561-rv5j1201	1856	1	Lymph	lymph	NN
cord-022561-rv5j1201	1856	2	then	then	RB
cord-022561-rv5j1201	1856	3	flows	flow	VBZ
cord-022561-rv5j1201	1856	4	down	down	IN
cord-022561-rv5j1201	1856	5	the	the	DT
cord-022561-rv5j1201	1856	6	trabecular	trabecular	JJ
cord-022561-rv5j1201	1856	7	sinuses	sinus	NNS
cord-022561-rv5j1201	1856	8	that	that	WDT
cord-022561-rv5j1201	1856	9	line	line	VBP
cord-022561-rv5j1201	1856	10	the	the	DT
cord-022561-rv5j1201	1856	11	outer	outer	JJ
cord-022561-rv5j1201	1856	12	surface	surface	NN
cord-022561-rv5j1201	1856	13	of	of	IN
cord-022561-rv5j1201	1856	14	fibrous	fibrous	JJ
cord-022561-rv5j1201	1856	15	trabeculae	trabeculae	NNP
cord-022561-rv5j1201	1856	16	,	,	,
cord-022561-rv5j1201	1856	17	to	to	IN
cord-022561-rv5j1201	1856	18	the	the	DT
cord-022561-rv5j1201	1856	19	medullary	medullary	JJ
cord-022561-rv5j1201	1856	20	sinus	sinus	NN
cord-022561-rv5j1201	1856	21	,	,	,
cord-022561-rv5j1201	1856	22	and	and	CC
cord-022561-rv5j1201	1856	23	eventually	eventually	RB
cord-022561-rv5j1201	1856	24	exits	exit	VBZ
cord-022561-rv5j1201	1856	25	via	via	IN
cord-022561-rv5j1201	1856	26	efferent	efferent	JJ
cord-022561-rv5j1201	1856	27	vessels	vessel	NNS
cord-022561-rv5j1201	1856	28	.	.	.
cord-022561-rv5j1201	1857	1	As	as	IN
cord-022561-rv5j1201	1857	2	antigens	antigen	NNS
cord-022561-rv5j1201	1857	3	within	within	IN
cord-022561-rv5j1201	1857	4	the	the	DT
cord-022561-rv5j1201	1857	5	lymph	lymph	NN
cord-022561-rv5j1201	1857	6	travel	travel	VBP
cord-022561-rv5j1201	1857	7	through	through	IN
cord-022561-rv5j1201	1857	8	the	the	DT
cord-022561-rv5j1201	1857	9	sinuses	sinus	NNS
cord-022561-rv5j1201	1857	10	,	,	,
cord-022561-rv5j1201	1857	11	they	-PRON-	PRP
cord-022561-rv5j1201	1857	12	are	be	VBP
cord-022561-rv5j1201	1857	13	captured	capture	VBN
cord-022561-rv5j1201	1857	14	and	and	CC
cord-022561-rv5j1201	1857	15	processed	process	VBN
cord-022561-rv5j1201	1857	16	by	by	IN
cord-022561-rv5j1201	1857	17	macrophages	macrophage	NNS
cord-022561-rv5j1201	1857	18	and	and	CC
cord-022561-rv5j1201	1857	19	DCs	dc	NNS
cord-022561-rv5j1201	1857	20	.	.	.
cord-022561-rv5j1201	1858	1	Alternatively	alternatively	RB
cord-022561-rv5j1201	1858	2	,	,	,
cord-022561-rv5j1201	1858	3	DCs	DCs	NNP
cord-022561-rv5j1201	1858	4	charged	charge	VBD
cord-022561-rv5j1201	1858	5	with	with	IN
cord-022561-rv5j1201	1858	6	antigen	antigen	NN
cord-022561-rv5j1201	1858	7	can	can	MD
cord-022561-rv5j1201	1858	8	migrate	migrate	VB
cord-022561-rv5j1201	1858	9	within	within	IN
cord-022561-rv5j1201	1858	10	blood	blood	NN
cord-022561-rv5j1201	1858	11	vessels	vessel	NNS
cord-022561-rv5j1201	1858	12	to	to	IN
cord-022561-rv5j1201	1858	13	the	the	DT
cord-022561-rv5j1201	1858	14	node	node	NN
cord-022561-rv5j1201	1858	15	and	and	CC
cord-022561-rv5j1201	1858	16	enter	enter	VB
cord-022561-rv5j1201	1858	17	the	the	DT
cord-022561-rv5j1201	1858	18	paracortex	paracortex	NN
cord-022561-rv5j1201	1858	19	via	via	IN
cord-022561-rv5j1201	1858	20	the	the	DT
cord-022561-rv5j1201	1858	21	HEVs	hev	NNS
cord-022561-rv5j1201	1858	22	.	.	.
cord-022561-rv5j1201	1859	1	Circulating	circulate	VBG
cord-022561-rv5j1201	1859	2	B	b	NN
cord-022561-rv5j1201	1859	3	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	1859	4	also	also	RB
cord-022561-rv5j1201	1859	5	enter	enter	VBP
cord-022561-rv5j1201	1859	6	across	across	IN
cord-022561-rv5j1201	1859	7	the	the	DT
cord-022561-rv5j1201	1859	8	HEVs	hev	NNS
cord-022561-rv5j1201	1859	9	,	,	,
cord-022561-rv5j1201	1859	10	and	and	CC
cord-022561-rv5j1201	1859	11	if	if	IN
cord-022561-rv5j1201	1859	12	they	-PRON-	PRP
cord-022561-rv5j1201	1859	13	encounter	encounter	VBP
cord-022561-rv5j1201	1859	14	antigen	antigen	NN
cord-022561-rv5j1201	1859	15	-	-	HYPH
cord-022561-rv5j1201	1859	16	bearing	bear	VBG
cord-022561-rv5j1201	1859	17	DCs	dc	NNS
cord-022561-rv5j1201	1859	18	,	,	,
cord-022561-rv5j1201	1859	19	there	there	EX
cord-022561-rv5j1201	1859	20	is	be	VBZ
cord-022561-rv5j1201	1859	21	a	a	DT
cord-022561-rv5j1201	1859	22	local	local	JJ
cord-022561-rv5j1201	1859	23	reaction	reaction	NN
cord-022561-rv5j1201	1859	24	involving	involve	VBG
cord-022561-rv5j1201	1859	25	the	the	DT
cord-022561-rv5j1201	1859	26	appropriate	appropriate	JJ
cord-022561-rv5j1201	1859	27	T	T	NNP
cord-022561-rv5j1201	1859	28	helper	helper	NN
cord-022561-rv5j1201	1859	29	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	1859	30	,	,	,
cord-022561-rv5j1201	1859	31	B	b	NN
cord-022561-rv5j1201	1859	32	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	1859	33	,	,	,
cord-022561-rv5j1201	1859	34	and	and	CC
cord-022561-rv5j1201	1859	35	DCs	dc	NNS
cord-022561-rv5j1201	1859	36	.	.	.
cord-022561-rv5j1201	1860	1	This	this	DT
cord-022561-rv5j1201	1860	2	results	result	VBZ
cord-022561-rv5j1201	1860	3	in	in	IN
cord-022561-rv5j1201	1860	4	the	the	DT
cord-022561-rv5j1201	1860	5	migration	migration	NN
cord-022561-rv5j1201	1860	6	of	of	IN
cord-022561-rv5j1201	1860	7	the	the	DT
cord-022561-rv5j1201	1860	8	activated	activate	VBN
cord-022561-rv5j1201	1860	9	B	b	NN
cord-022561-rv5j1201	1860	10	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	1860	11	to	to	IN
cord-022561-rv5j1201	1860	12	a	a	DT
cord-022561-rv5j1201	1860	13	primary	primary	JJ
cord-022561-rv5j1201	1860	14	follicle	follicle	NN
cord-022561-rv5j1201	1860	15	,	,	,
cord-022561-rv5j1201	1860	16	where	where	WRB
cord-022561-rv5j1201	1860	17	they	-PRON-	PRP
cord-022561-rv5j1201	1860	18	initiate	initiate	VBP
cord-022561-rv5j1201	1860	19	formation	formation	NN
cord-022561-rv5j1201	1860	20	of	of	IN
cord-022561-rv5j1201	1860	21	a	a	DT
cord-022561-rv5j1201	1860	22	germinal	germinal	JJ
cord-022561-rv5j1201	1860	23	center	center	NN
cord-022561-rv5j1201	1860	24	.	.	.
cord-022561-rv5j1201	1861	1	Germinal	germinal	JJ
cord-022561-rv5j1201	1861	2	centers	center	NNS
cord-022561-rv5j1201	1861	3	,	,	,
cord-022561-rv5j1201	1861	4	upon	upon	IN
cord-022561-rv5j1201	1861	5	migration	migration	NN
cord-022561-rv5j1201	1861	6	of	of	IN
cord-022561-rv5j1201	1861	7	antigen	antigen	NN
cord-022561-rv5j1201	1861	8	-	-	HYPH
cord-022561-rv5j1201	1861	9	activated	activate	VBN
cord-022561-rv5j1201	1861	10	B	b	NN
cord-022561-rv5j1201	1861	11	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	1861	12	,	,	,
cord-022561-rv5j1201	1861	13	develop	develop	VB
cord-022561-rv5j1201	1861	14	a	a	DT
cord-022561-rv5j1201	1861	15	characteristic	characteristic	JJ
cord-022561-rv5j1201	1861	16	architecture	architecture	NN
cord-022561-rv5j1201	1861	17	.	.	.
cord-022561-rv5j1201	1862	1	Distinct	distinct	JJ
cord-022561-rv5j1201	1862	2	polarity	polarity	NN
cord-022561-rv5j1201	1862	3	composed	compose	VBN
cord-022561-rv5j1201	1862	4	of	of	IN
cord-022561-rv5j1201	1862	5	a	a	DT
cord-022561-rv5j1201	1862	6	superficial	superficial	JJ
cord-022561-rv5j1201	1862	7	or	or	CC
cord-022561-rv5j1201	1862	8	light	light	JJ
cord-022561-rv5j1201	1862	9	zone	zone	NN
cord-022561-rv5j1201	1862	10	and	and	CC
cord-022561-rv5j1201	1862	11	a	a	DT
cord-022561-rv5j1201	1862	12	deep	deep	JJ
cord-022561-rv5j1201	1862	13	dark	dark	JJ
cord-022561-rv5j1201	1862	14	zone	zone	NN
cord-022561-rv5j1201	1862	15	is	be	VBZ
cord-022561-rv5j1201	1862	16	present	present	JJ
cord-022561-rv5j1201	1862	17	in	in	IN
cord-022561-rv5j1201	1862	18	cases	case	NNS
cord-022561-rv5j1201	1862	19	of	of	IN
cord-022561-rv5j1201	1862	20	antigenic	antigenic	JJ
cord-022561-rv5j1201	1862	21	stimulation	stimulation	NN
cord-022561-rv5j1201	1862	22	.	.	.
cord-022561-rv5j1201	1863	1	The	the	DT
cord-022561-rv5j1201	1863	2	light	light	JJ
cord-022561-rv5j1201	1863	3	zone	zone	NN
cord-022561-rv5j1201	1863	4	,	,	,
cord-022561-rv5j1201	1863	5	orientated	orientate	VBN
cord-022561-rv5j1201	1863	6	at	at	IN
cord-022561-rv5j1201	1863	7	the	the	DT
cord-022561-rv5j1201	1863	8	source	source	NN
cord-022561-rv5j1201	1863	9	of	of	IN
cord-022561-rv5j1201	1863	10	antigen	antigen	NN
cord-022561-rv5j1201	1863	11	,	,	,
cord-022561-rv5j1201	1863	12	consists	consist	VBZ
cord-022561-rv5j1201	1863	13	mainly	mainly	RB
cord-022561-rv5j1201	1863	14	of	of	IN
cord-022561-rv5j1201	1863	15	small	small	JJ
cord-022561-rv5j1201	1863	16	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	1863	17	,	,	,
cord-022561-rv5j1201	1863	18	called	call	VBN
cord-022561-rv5j1201	1863	19	centrocytes	centrocytes	NNP
cord-022561-rv5j1201	1863	20	,	,	,
cord-022561-rv5j1201	1863	21	which	which	WDT
cord-022561-rv5j1201	1863	22	have	have	VBP
cord-022561-rv5j1201	1863	23	moderate	moderate	JJ
cord-022561-rv5j1201	1863	24	amounts	amount	NNS
cord-022561-rv5j1201	1863	25	of	of	IN
cord-022561-rv5j1201	1863	26	pale	pale	JJ
cord-022561-rv5j1201	1863	27	eosinophilic	eosinophilic	JJ
cord-022561-rv5j1201	1863	28	cytoplasm	cytoplasm	NN
cord-022561-rv5j1201	1863	29	.	.	.
cord-022561-rv5j1201	1864	1	The	the	DT
cord-022561-rv5j1201	1864	2	cells	cell	NNS
cord-022561-rv5j1201	1864	3	of	of	IN
cord-022561-rv5j1201	1864	4	the	the	DT
cord-022561-rv5j1201	1864	5	dark	dark	JJ
cord-022561-rv5j1201	1864	6	zone	zone	NN
cord-022561-rv5j1201	1864	7	,	,	,
cord-022561-rv5j1201	1864	8	called	call	VBN
cord-022561-rv5j1201	1864	9	centroblasts	centroblasts	NNP
cord-022561-rv5j1201	1864	10	,	,	,
cord-022561-rv5j1201	1864	11	are	be	VBP
cord-022561-rv5j1201	1864	12	large	large	JJ
cord-022561-rv5j1201	1864	13	,	,	,
cord-022561-rv5j1201	1864	14	densely	densely	RB
cord-022561-rv5j1201	1864	15	packed	pack	VBN
cord-022561-rv5j1201	1864	16	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	1864	17	with	with	IN
cord-022561-rv5j1201	1864	18	scant	scant	JJ
cord-022561-rv5j1201	1864	19	cytoplasm	cytoplasm	NN
cord-022561-rv5j1201	1864	20	,	,	,
cord-022561-rv5j1201	1864	21	giving	give	VBG
cord-022561-rv5j1201	1864	22	this	this	DT
cord-022561-rv5j1201	1864	23	area	area	NN
cord-022561-rv5j1201	1864	24	a	a	DT
cord-022561-rv5j1201	1864	25	darker	dark	JJR
cord-022561-rv5j1201	1864	26	appearance	appearance	NN
cord-022561-rv5j1201	1864	27	on	on	IN
cord-022561-rv5j1201	1864	28	H&E	H&E	NNP
cord-022561-rv5j1201	1864	29	staining	stain	VBG
cord-022561-rv5j1201	1864	30	.	.	.
cord-022561-rv5j1201	1865	1	The	the	DT
cord-022561-rv5j1201	1865	2	centroblasts	centroblast	NNS
cord-022561-rv5j1201	1865	3	undergo	undergo	VBP
cord-022561-rv5j1201	1865	4	somatic	somatic	JJ
cord-022561-rv5j1201	1865	5	mutations	mutation	NNS
cord-022561-rv5j1201	1865	6	of	of	IN
cord-022561-rv5j1201	1865	7	the	the	DT
cord-022561-rv5j1201	1865	8	variable	variable	JJ
cord-022561-rv5j1201	1865	9	regions	region	NNS
cord-022561-rv5j1201	1865	10	of	of	IN
cord-022561-rv5j1201	1865	11	the	the	DT
cord-022561-rv5j1201	1865	12	immunoglobulin	immunoglobulin	NN
cord-022561-rv5j1201	1865	13	gene	gene	NN
cord-022561-rv5j1201	1865	14	,	,	,
cord-022561-rv5j1201	1865	15	followed	follow	VBN
cord-022561-rv5j1201	1865	16	by	by	IN
cord-022561-rv5j1201	1865	17	isotype	isotype	NN
cord-022561-rv5j1201	1865	18	class	class	NN
cord-022561-rv5j1201	1865	19	switching	switching	NN
cord-022561-rv5j1201	1865	20	(	(	-LRB-
cord-022561-rv5j1201	1865	21	from	from	IN
cord-022561-rv5j1201	1865	22	IgM	IgM	NNP
cord-022561-rv5j1201	1865	23	to	to	IN
cord-022561-rv5j1201	1865	24	IgG	IgG	NNP
cord-022561-rv5j1201	1865	25	or	or	CC
cord-022561-rv5j1201	1865	26	IgA	IgA	NNP
cord-022561-rv5j1201	1865	27	)	)	-RRB-
cord-022561-rv5j1201	1865	28	.	.	.
cord-022561-rv5j1201	1866	1	During	during	IN
cord-022561-rv5j1201	1866	2	this	this	DT
cord-022561-rv5j1201	1866	3	process	process	NN
cord-022561-rv5j1201	1866	4	most	most	RBS
cord-022561-rv5j1201	1866	5	centroblasts	centroblast	NNS
cord-022561-rv5j1201	1866	6	undergo	undergo	VB
cord-022561-rv5j1201	1866	7	apoptosis	apoptosis	NN
cord-022561-rv5j1201	1866	8	,	,	,
cord-022561-rv5j1201	1866	9	and	and	CC
cord-022561-rv5j1201	1866	10	cell	cell	NN
cord-022561-rv5j1201	1866	11	fragments	fragment	NNS
cord-022561-rv5j1201	1866	12	are	be	VBP
cord-022561-rv5j1201	1866	13	phagocytized	phagocytize	VBN
cord-022561-rv5j1201	1866	14	by	by	IN
cord-022561-rv5j1201	1866	15	macrophages	macrophage	NNS
cord-022561-rv5j1201	1866	16	,	,	,
cord-022561-rv5j1201	1866	17	which	which	WDT
cord-022561-rv5j1201	1866	18	are	be	VBP
cord-022561-rv5j1201	1866	19	then	then	RB
cord-022561-rv5j1201	1866	20	termed	term	VBN
cord-022561-rv5j1201	1866	21	tingible	tingible	JJ
cord-022561-rv5j1201	1866	22	(	(	-LRB-
cord-022561-rv5j1201	1866	23	stainable	stainable	JJ
cord-022561-rv5j1201	1866	24	)	)	-RRB-
cord-022561-rv5j1201	1866	25	body	body	NN
cord-022561-rv5j1201	1866	26	macrophages	macrophage	NNS
cord-022561-rv5j1201	1866	27	.	.	.
cord-022561-rv5j1201	1867	1	The	the	DT
cord-022561-rv5j1201	1867	2	cells	cell	NNS
cord-022561-rv5j1201	1867	3	that	that	WDT
cord-022561-rv5j1201	1867	4	have	have	VBP
cord-022561-rv5j1201	1867	5	survived	survive	VBN
cord-022561-rv5j1201	1867	6	the	the	DT
cord-022561-rv5j1201	1867	7	affinity	affinity	NN
cord-022561-rv5j1201	1867	8	maturation	maturation	NN
cord-022561-rv5j1201	1867	9	process	process	NN
cord-022561-rv5j1201	1867	10	are	be	VBP
cord-022561-rv5j1201	1867	11	now	now	RB
cord-022561-rv5j1201	1867	12	called	call	VBN
cord-022561-rv5j1201	1867	13	centrocytes	centrocyte	NNS
cord-022561-rv5j1201	1867	14	and	and	CC
cord-022561-rv5j1201	1867	15	along	along	IN
cord-022561-rv5j1201	1867	16	with	with	IN
cord-022561-rv5j1201	1867	17	T	T	NNP
cord-022561-rv5j1201	1867	18	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	1867	19	and	and	CC
cord-022561-rv5j1201	1867	20	follicular	follicular	JJ
cord-022561-rv5j1201	1867	21	DCs	dc	NNS
cord-022561-rv5j1201	1867	22	,	,	,
cord-022561-rv5j1201	1867	23	populate	populate	VB
cord-022561-rv5j1201	1867	24	the	the	DT
cord-022561-rv5j1201	1867	25	germinal	germinal	JJ
cord-022561-rv5j1201	1867	26	center	center	NNP
cord-022561-rv5j1201	1867	27	light	light	NN
cord-022561-rv5j1201	1867	28	zone	zone	NN
cord-022561-rv5j1201	1867	29	.	.	.
cord-022561-rv5j1201	1868	1	These	these	DT
cord-022561-rv5j1201	1868	2	post	post	JJ
cord-022561-rv5j1201	1868	3	-	-	JJ
cord-022561-rv5j1201	1868	4	germinal	germinal	JJ
cord-022561-rv5j1201	1868	5	center	center	NN
cord-022561-rv5j1201	1868	6	B	B	NNP
cord-022561-rv5j1201	1868	7	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	1868	8	leave	leave	VBP
cord-022561-rv5j1201	1868	9	the	the	DT
cord-022561-rv5j1201	1868	10	follicle	follicle	NN
cord-022561-rv5j1201	1868	11	as	as	IN
cord-022561-rv5j1201	1868	12	plasma	plasma	NN
cord-022561-rv5j1201	1868	13	cell	cell	NN
cord-022561-rv5j1201	1868	14	precursors	precursor	NNS
cord-022561-rv5j1201	1868	15	(	(	-LRB-
cord-022561-rv5j1201	1868	16	immunoblasts	immunoblast	NNS
cord-022561-rv5j1201	1868	17	or	or	CC
cord-022561-rv5j1201	1868	18	plasmablasts	plasmablast	NNS
cord-022561-rv5j1201	1868	19	)	)	-RRB-
cord-022561-rv5j1201	1868	20	and	and	CC
cord-022561-rv5j1201	1868	21	migrate	migrate	VB
cord-022561-rv5j1201	1868	22	from	from	IN
cord-022561-rv5j1201	1868	23	the	the	DT
cord-022561-rv5j1201	1868	24	cortex	cortex	NN
cord-022561-rv5j1201	1868	25	to	to	IN
cord-022561-rv5j1201	1868	26	the	the	DT
cord-022561-rv5j1201	1868	27	medullary	medullary	JJ
cord-022561-rv5j1201	1868	28	cords	cord	NNS
cord-022561-rv5j1201	1868	29	,	,	,
cord-022561-rv5j1201	1868	30	where	where	WRB
cord-022561-rv5j1201	1868	31	they	-PRON-	PRP
cord-022561-rv5j1201	1868	32	mature	mature	VBP
cord-022561-rv5j1201	1868	33	and	and	CC
cord-022561-rv5j1201	1868	34	excrete	excrete	VB
cord-022561-rv5j1201	1868	35	antibody	antibody	NN
cord-022561-rv5j1201	1868	36	into	into	IN
cord-022561-rv5j1201	1868	37	the	the	DT
cord-022561-rv5j1201	1868	38	efferent	efferent	JJ
cord-022561-rv5j1201	1868	39	lymph	lymph	NN
cord-022561-rv5j1201	1868	40	.	.	.
cord-022561-rv5j1201	1869	1	Some	some	DT
cord-022561-rv5j1201	1869	2	of	of	IN
cord-022561-rv5j1201	1869	3	these	these	DT
cord-022561-rv5j1201	1869	4	cells	cell	NNS
cord-022561-rv5j1201	1869	5	may	may	MD
cord-022561-rv5j1201	1869	6	colonize	colonize	VB
cord-022561-rv5j1201	1869	7	the	the	DT
cord-022561-rv5j1201	1869	8	region	region	NN
cord-022561-rv5j1201	1869	9	surrounding	surround	VBG
cord-022561-rv5j1201	1869	10	the	the	DT
cord-022561-rv5j1201	1869	11	mantle	mantle	NN
cord-022561-rv5j1201	1869	12	cell	cell	NN
cord-022561-rv5j1201	1869	13	zone	zone	NN
cord-022561-rv5j1201	1869	14	to	to	TO
cord-022561-rv5j1201	1869	15	form	form	VB
cord-022561-rv5j1201	1869	16	a	a	DT
cord-022561-rv5j1201	1869	17	marginal	marginal	JJ
cord-022561-rv5j1201	1869	18	zone	zone	NN
cord-022561-rv5j1201	1869	19	.	.	.
cord-022561-rv5j1201	1870	1	Marginal	marginal	JJ
cord-022561-rv5j1201	1870	2	zones	zone	NNS
cord-022561-rv5j1201	1870	3	are	be	VBP
cord-022561-rv5j1201	1870	4	apparent	apparent	JJ
cord-022561-rv5j1201	1870	5	only	only	RB
cord-022561-rv5j1201	1870	6	in	in	IN
cord-022561-rv5j1201	1870	7	situations	situation	NNS
cord-022561-rv5j1201	1870	8	of	of	IN
cord-022561-rv5j1201	1870	9	prolonged	prolonged	JJ
cord-022561-rv5j1201	1870	10	and	and	CC
cord-022561-rv5j1201	1870	11	intense	intense	JJ
cord-022561-rv5j1201	1870	12	immune	immune	JJ
cord-022561-rv5j1201	1870	13	stimulation	stimulation	NN
cord-022561-rv5j1201	1870	14	and	and	CC
cord-022561-rv5j1201	1870	15	serve	serve	VB
cord-022561-rv5j1201	1870	16	as	as	IN
cord-022561-rv5j1201	1870	17	a	a	DT
cord-022561-rv5j1201	1870	18	reservoir	reservoir	NN
cord-022561-rv5j1201	1870	19	of	of	IN
cord-022561-rv5j1201	1870	20	memory	memory	NN
cord-022561-rv5j1201	1870	21	cells	cell	NNS
cord-022561-rv5j1201	1870	22	.	.	.
cord-022561-rv5j1201	1871	1	The	the	DT
cord-022561-rv5j1201	1871	2	elliptical	elliptical	JJ
cord-022561-rv5j1201	1871	3	mantle	mantle	NN
cord-022561-rv5j1201	1871	4	cell	cell	NN
cord-022561-rv5j1201	1871	5	cuff	cuff	NN
cord-022561-rv5j1201	1871	6	is	be	VBZ
cord-022561-rv5j1201	1871	7	wider	wide	JJR
cord-022561-rv5j1201	1871	8	over	over	IN
cord-022561-rv5j1201	1871	9	the	the	DT
cord-022561-rv5j1201	1871	10	light	light	JJ
cord-022561-rv5j1201	1871	11	pole	pole	NN
cord-022561-rv5j1201	1871	12	of	of	IN
cord-022561-rv5j1201	1871	13	the	the	DT
cord-022561-rv5j1201	1871	14	follicle	follicle	NN
cord-022561-rv5j1201	1871	15	,	,	,
cord-022561-rv5j1201	1871	16	though	though	IN
cord-022561-rv5j1201	1871	17	in	in	IN
cord-022561-rv5j1201	1871	18	instances	instance	NNS
cord-022561-rv5j1201	1871	19	of	of	IN
cord-022561-rv5j1201	1871	20	strong	strong	JJ
cord-022561-rv5j1201	1871	21	antigenic	antigenic	JJ
cord-022561-rv5j1201	1871	22	stimulation	stimulation	NN
cord-022561-rv5j1201	1871	23	,	,	,
cord-022561-rv5j1201	1871	24	the	the	DT
cord-022561-rv5j1201	1871	25	cuffs	cuff	NNS
cord-022561-rv5j1201	1871	26	can	can	MD
cord-022561-rv5j1201	1871	27	completely	completely	RB
cord-022561-rv5j1201	1871	28	encircle	encircle	VB
cord-022561-rv5j1201	1871	29	the	the	DT
cord-022561-rv5j1201	1871	30	germinal	germinal	JJ
cord-022561-rv5j1201	1871	31	center	center	NN
cord-022561-rv5j1201	1871	32	.	.	.
cord-022561-rv5j1201	1872	1	Responses	response	NNS
cord-022561-rv5j1201	1872	2	to	to	IN
cord-022561-rv5j1201	1872	3	injury	injury	NN
cord-022561-rv5j1201	1872	4	are	be	VBP
cord-022561-rv5j1201	1872	5	listed	list	VBN
cord-022561-rv5j1201	1872	6	in	in	IN
cord-022561-rv5j1201	1872	7	Box	Box	NNP
cord-022561-rv5j1201	1872	8	13	13	CD
cord-022561-rv5j1201	1872	9	-	-	SYM
cord-022561-rv5j1201	1872	10	9	9	CD
cord-022561-rv5j1201	1872	11	,	,	,
cord-022561-rv5j1201	1872	12	and	and	CC
cord-022561-rv5j1201	1872	13	the	the	DT
cord-022561-rv5j1201	1872	14	responses	response	NNS
cord-022561-rv5j1201	1872	15	are	be	VBP
cord-022561-rv5j1201	1872	16	discussed	discuss	VBN
cord-022561-rv5j1201	1872	17	on	on	IN
cord-022561-rv5j1201	1872	18	the	the	DT
cord-022561-rv5j1201	1872	19	basis	basis	NN
cord-022561-rv5j1201	1872	20	of	of	IN
cord-022561-rv5j1201	1872	21	the	the	DT
cord-022561-rv5j1201	1872	22	following	follow	VBG
cord-022561-rv5j1201	1872	23	systems	system	NNS
cord-022561-rv5j1201	1872	24	:	:	:
cord-022561-rv5j1201	1872	25	sinus	sinus	NNP
cord-022561-rv5j1201	1872	26	histiocytes	histiocyte	NNS
cord-022561-rv5j1201	1872	27	of	of	IN
cord-022561-rv5j1201	1872	28	the	the	DT
cord-022561-rv5j1201	1872	29	monocyte	monocyte	JJ
cord-022561-rv5j1201	1872	30	-	-	HYPH
cord-022561-rv5j1201	1872	31	macrophage	macrophage	NN
cord-022561-rv5j1201	1872	32	system	system	NN
cord-022561-rv5j1201	1872	33	,	,	,
cord-022561-rv5j1201	1872	34	cortex	cortex	NN
cord-022561-rv5j1201	1872	35	,	,	,
cord-022561-rv5j1201	1872	36	paracortex	paracortex	NNP
cord-022561-rv5j1201	1872	37	,	,	,
cord-022561-rv5j1201	1872	38	and	and	CC
cord-022561-rv5j1201	1872	39	medulla	medulla	NN
cord-022561-rv5j1201	1872	40	(	(	-LRB-
cord-022561-rv5j1201	1872	41	medullary	medullary	JJ
cord-022561-rv5j1201	1872	42	sinuses	sinus	NNS
cord-022561-rv5j1201	1872	43	and	and	CC
cord-022561-rv5j1201	1872	44	medullary	medullary	JJ
cord-022561-rv5j1201	1872	45	cords	cord	NNS
cord-022561-rv5j1201	1872	46	)	)	-RRB-
cord-022561-rv5j1201	1872	47	.	.	.
cord-022561-rv5j1201	1873	1	Generally	generally	RB
cord-022561-rv5j1201	1873	2	,	,	,
cord-022561-rv5j1201	1873	3	enlarged	enlarged	JJ
cord-022561-rv5j1201	1873	4	lymph	lymph	NN
cord-022561-rv5j1201	1873	5	nodes	node	NNS
cord-022561-rv5j1201	1873	6	can	can	MD
cord-022561-rv5j1201	1873	7	be	be	VB
cord-022561-rv5j1201	1873	8	distributed	distribute	VBN
cord-022561-rv5j1201	1873	9	in	in	IN
cord-022561-rv5j1201	1873	10	several	several	JJ
cord-022561-rv5j1201	1873	11	different	different	JJ
cord-022561-rv5j1201	1873	12	patterns	pattern	NNS
cord-022561-rv5j1201	1873	13	in	in	IN
cord-022561-rv5j1201	1873	14	the	the	DT
cord-022561-rv5j1201	1873	15	body	body	NN
cord-022561-rv5j1201	1873	16	.	.	.
cord-022561-rv5j1201	1874	1	First	first	RB
cord-022561-rv5j1201	1874	2	,	,	,
cord-022561-rv5j1201	1874	3	all	all	DT
cord-022561-rv5j1201	1874	4	lymph	lymph	NN
cord-022561-rv5j1201	1874	5	nodes	node	NNS
cord-022561-rv5j1201	1874	6	throughout	throughout	IN
cord-022561-rv5j1201	1874	7	the	the	DT
cord-022561-rv5j1201	1874	8	body	body	NN
cord-022561-rv5j1201	1874	9	(	(	-LRB-
cord-022561-rv5j1201	1874	10	systemic	systemic	JJ
cord-022561-rv5j1201	1874	11	or	or	CC
cord-022561-rv5j1201	1874	12	generalized	generalized	JJ
cord-022561-rv5j1201	1874	13	)	)	-RRB-
cord-022561-rv5j1201	1874	14	may	may	MD
cord-022561-rv5j1201	1874	15	be	be	VB
cord-022561-rv5j1201	1874	16	enlarged	enlarge	VBN
cord-022561-rv5j1201	1874	17	(	(	-LRB-
cord-022561-rv5j1201	1874	18	lymphadenopathy	lymphadenopathy	JJ
cord-022561-rv5j1201	1874	19	or	or	CC
cord-022561-rv5j1201	1874	20	lymphadenomegaly	lymphadenomegaly	NNP
cord-022561-rv5j1201	1874	21	)	)	-RRB-
cord-022561-rv5j1201	1874	22	.	.	.
cord-022561-rv5j1201	1875	1	This	this	DT
cord-022561-rv5j1201	1875	2	pattern	pattern	NN
cord-022561-rv5j1201	1875	3	is	be	VBZ
cord-022561-rv5j1201	1875	4	usually	usually	RB
cord-022561-rv5j1201	1875	5	attributed	attribute	VBN
cord-022561-rv5j1201	1875	6	to	to	IN
cord-022561-rv5j1201	1875	7	systemic	systemic	JJ
cord-022561-rv5j1201	1875	8	infectious	infectious	JJ
cord-022561-rv5j1201	1875	9	,	,	,
cord-022561-rv5j1201	1875	10	inflammatory	inflammatory	JJ
cord-022561-rv5j1201	1875	11	,	,	,
cord-022561-rv5j1201	1875	12	or	or	CC
cord-022561-rv5j1201	1875	13	neoplastic	neoplastic	JJ
cord-022561-rv5j1201	1875	14	processes	process	NNS
cord-022561-rv5j1201	1875	15	.	.	.
cord-022561-rv5j1201	1876	1	If	if	IN
cord-022561-rv5j1201	1876	2	a	a	DT
cord-022561-rv5j1201	1876	3	single	single	JJ
cord-022561-rv5j1201	1876	4	lymph	lymph	NN
cord-022561-rv5j1201	1876	5	node	node	NN
cord-022561-rv5j1201	1876	6	or	or	CC
cord-022561-rv5j1201	1876	7	regional	regional	JJ
cord-022561-rv5j1201	1876	8	chain	chain	NN
cord-022561-rv5j1201	1876	9	of	of	IN
cord-022561-rv5j1201	1876	10	nodes	node	NNS
cord-022561-rv5j1201	1876	11	is	be	VBZ
cord-022561-rv5j1201	1876	12	enlarged	enlarge	VBN
cord-022561-rv5j1201	1876	13	,	,	,
cord-022561-rv5j1201	1876	14	then	then	RB
cord-022561-rv5j1201	1876	15	the	the	DT
cord-022561-rv5j1201	1876	16	area	area	NN
cord-022561-rv5j1201	1876	17	drained	drain	VBN
cord-022561-rv5j1201	1876	18	by	by	IN
cord-022561-rv5j1201	1876	19	that	that	DT
cord-022561-rv5j1201	1876	20	node	node	NN
cord-022561-rv5j1201	1876	21	should	should	MD
cord-022561-rv5j1201	1876	22	be	be	VB
cord-022561-rv5j1201	1876	23	checked	check	VBN
cord-022561-rv5j1201	1876	24	for	for	IN
cord-022561-rv5j1201	1876	25	lesions	lesion	NNS
cord-022561-rv5j1201	1876	26	(	(	-LRB-
cord-022561-rv5j1201	1876	27	e.g.	e.g.	RB
cord-022561-rv5j1201	1876	28	,	,	,
cord-022561-rv5j1201	1876	29	evaluate	evaluate	VB
cord-022561-rv5j1201	1876	30	the	the	DT
cord-022561-rv5j1201	1876	31	oral	oral	JJ
cord-022561-rv5j1201	1876	32	cavity	cavity	NN
cord-022561-rv5j1201	1876	33	if	if	IN
cord-022561-rv5j1201	1876	34	the	the	DT
cord-022561-rv5j1201	1876	35	mandibular	mandibular	JJ
cord-022561-rv5j1201	1876	36	lymph	lymph	NN
cord-022561-rv5j1201	1876	37	nodes	node	NNS
cord-022561-rv5j1201	1876	38	are	be	VBP
cord-022561-rv5j1201	1876	39	enlarged	enlarge	VBN
cord-022561-rv5j1201	1876	40	)	)	-RRB-
cord-022561-rv5j1201	1876	41	.	.	.
cord-022561-rv5j1201	1877	1	Thus	thus	RB
cord-022561-rv5j1201	1877	2	it	-PRON-	PRP
cord-022561-rv5j1201	1877	3	is	be	VBZ
cord-022561-rv5j1201	1877	4	important	important	JJ
cord-022561-rv5j1201	1877	5	to	to	TO
cord-022561-rv5j1201	1877	6	know	know	VB
cord-022561-rv5j1201	1877	7	the	the	DT
cord-022561-rv5j1201	1877	8	area	area	NN
cord-022561-rv5j1201	1877	9	drained	drain	VBN
cord-022561-rv5j1201	1877	10	by	by	IN
cord-022561-rv5j1201	1877	11	specific	specific	JJ
cord-022561-rv5j1201	1877	12	lymph	lymph	NN
cord-022561-rv5j1201	1877	13	nodes	node	NNS
cord-022561-rv5j1201	1877	14	.	.	.
cord-022561-rv5j1201	1878	1	Mesenteric	mesenteric	JJ
cord-022561-rv5j1201	1878	2	lymph	lymph	NN
cord-022561-rv5j1201	1878	3	nodes	node	NNS
cord-022561-rv5j1201	1878	4	are	be	VBP
cord-022561-rv5j1201	1878	5	normally	normally	RB
cord-022561-rv5j1201	1878	6	larger	large	JJR
cord-022561-rv5j1201	1878	7	because	because	IN
cord-022561-rv5j1201	1878	8	of	of	IN
cord-022561-rv5j1201	1878	9	follicular	follicular	JJ
cord-022561-rv5j1201	1878	10	Approximately	approximately	RB
cord-022561-rv5j1201	1878	11	90	90	CD
cord-022561-rv5j1201	1878	12	%	%	NN
cord-022561-rv5j1201	1878	13	to	to	TO
cord-022561-rv5j1201	1878	14	95	95	CD
cord-022561-rv5j1201	1878	15	%	%	NN
cord-022561-rv5j1201	1878	16	of	of	IN
cord-022561-rv5j1201	1878	17	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	1878	18	enter	enter	VBP
cord-022561-rv5j1201	1878	19	lymph	lymph	NN
cord-022561-rv5j1201	1878	20	nodes	node	NNS
cord-022561-rv5j1201	1878	21	through	through	IN
cord-022561-rv5j1201	1878	22	the	the	DT
cord-022561-rv5j1201	1878	23	HEVs	hev	NNS
cord-022561-rv5j1201	1878	24	,	,	,
cord-022561-rv5j1201	1878	25	which	which	WDT
cord-022561-rv5j1201	1878	26	also	also	RB
cord-022561-rv5j1201	1878	27	play	play	VBP
cord-022561-rv5j1201	1878	28	an	an	DT
cord-022561-rv5j1201	1878	29	important	important	JJ
cord-022561-rv5j1201	1878	30	role	role	NN
cord-022561-rv5j1201	1878	31	in	in	IN
cord-022561-rv5j1201	1878	32	lymph	lymph	NN
cord-022561-rv5j1201	1878	33	fluid	fluid	NN
cord-022561-rv5j1201	1878	34	balance	balance	NN
cord-022561-rv5j1201	1878	35	.	.	.
cord-022561-rv5j1201	1879	1	The	the	DT
cord-022561-rv5j1201	1879	2	lymphatic	lymphatic	JJ
cord-022561-rv5j1201	1879	3	vasculature	vasculature	NN
cord-022561-rv5j1201	1879	4	consists	consist	VBZ
cord-022561-rv5j1201	1879	5	of	of	IN
cord-022561-rv5j1201	1879	6	afferent	afferent	JJ
cord-022561-rv5j1201	1879	7	lymphatic	lymphatic	JJ
cord-022561-rv5j1201	1879	8	vessels	vessel	NNS
cord-022561-rv5j1201	1879	9	,	,	,
cord-022561-rv5j1201	1879	10	which	which	WDT
cord-022561-rv5j1201	1879	11	pierce	pierce	VBP
cord-022561-rv5j1201	1879	12	the	the	DT
cord-022561-rv5j1201	1879	13	capsule	capsule	NN
cord-022561-rv5j1201	1879	14	and	and	CC
cord-022561-rv5j1201	1879	15	drain	drain	VB
cord-022561-rv5j1201	1879	16	into	into	IN
cord-022561-rv5j1201	1879	17	the	the	DT
cord-022561-rv5j1201	1879	18	subcapsular	subcapsular	JJ
cord-022561-rv5j1201	1879	19	sinus	sinus	NNP
cord-022561-rv5j1201	1879	20	.	.	.
cord-022561-rv5j1201	1880	1	Lymph	lymph	NN
cord-022561-rv5j1201	1880	2	continues	continue	VBZ
cord-022561-rv5j1201	1880	3	to	to	TO
cord-022561-rv5j1201	1880	4	drain	drain	VB
cord-022561-rv5j1201	1880	5	through	through	IN
cord-022561-rv5j1201	1880	6	the	the	DT
cord-022561-rv5j1201	1880	7	trabecular	trabecular	JJ
cord-022561-rv5j1201	1880	8	sinuses	sinus	NNS
cord-022561-rv5j1201	1880	9	to	to	IN
cord-022561-rv5j1201	1880	10	the	the	DT
cord-022561-rv5j1201	1880	11	medullary	medullary	JJ
cord-022561-rv5j1201	1880	12	sinuses	sinus	NNS
cord-022561-rv5j1201	1880	13	and	and	CC
cord-022561-rv5j1201	1880	14	finally	finally	RB
cord-022561-rv5j1201	1880	15	exits	exit	VBZ
cord-022561-rv5j1201	1880	16	at	at	IN
cord-022561-rv5j1201	1880	17	the	the	DT
cord-022561-rv5j1201	1880	18	hilus	hilus	NNP
cord-022561-rv5j1201	1880	19	via	via	IN
cord-022561-rv5j1201	1880	20	efferent	efferent	JJ
cord-022561-rv5j1201	1880	21	lymphatic	lymphatic	JJ
cord-022561-rv5j1201	1880	22	vessels	vessel	NNS
cord-022561-rv5j1201	1880	23	.	.	.
cord-022561-rv5j1201	1881	1	All	all	DT
cord-022561-rv5j1201	1881	2	lymph	lymph	NN
cord-022561-rv5j1201	1881	3	nodes	node	NNS
cord-022561-rv5j1201	1881	4	receive	receive	VBP
cord-022561-rv5j1201	1881	5	afferent	afferent	JJ
cord-022561-rv5j1201	1881	6	lymphatic	lymphatic	NN
cord-022561-rv5j1201	1881	7	vessels	vessel	NNS
cord-022561-rv5j1201	1881	8	from	from	IN
cord-022561-rv5j1201	1881	9	specific	specific	JJ
cord-022561-rv5j1201	1881	10	areas	area	NNS
cord-022561-rv5j1201	1881	11	of	of	IN
cord-022561-rv5j1201	1881	12	the	the	DT
cord-022561-rv5j1201	1881	13	body	body	NN
cord-022561-rv5j1201	1881	14	.	.	.
cord-022561-rv5j1201	1882	1	The	the	DT
cord-022561-rv5j1201	1882	2	term	term	NN
cord-022561-rv5j1201	1882	3	lymphocenter	lymphocenter	NN
cord-022561-rv5j1201	1882	4	is	be	VBZ
cord-022561-rv5j1201	1882	5	often	often	RB
cord-022561-rv5j1201	1882	6	used	use	VBN
cord-022561-rv5j1201	1882	7	in	in	IN
cord-022561-rv5j1201	1882	8	veterinary	veterinary	JJ
cord-022561-rv5j1201	1882	9	anatomy	anatomy	NN
cord-022561-rv5j1201	1882	10	to	to	TO
cord-022561-rv5j1201	1882	11	describe	describe	VB
cord-022561-rv5j1201	1882	12	a	a	DT
cord-022561-rv5j1201	1882	13	lymph	lymph	NN
cord-022561-rv5j1201	1882	14	node	node	NN
cord-022561-rv5j1201	1882	15	or	or	CC
cord-022561-rv5j1201	1882	16	a	a	DT
cord-022561-rv5j1201	1882	17	group	group	NN
cord-022561-rv5j1201	1882	18	of	of	IN
cord-022561-rv5j1201	1882	19	lymph	lymph	NN
cord-022561-rv5j1201	1882	20	nodes	node	NNS
cord-022561-rv5j1201	1882	21	that	that	WDT
cord-022561-rv5j1201	1882	22	is	be	VBZ
cord-022561-rv5j1201	1882	23	consistently	consistently	RB
cord-022561-rv5j1201	1882	24	present	present	JJ
cord-022561-rv5j1201	1882	25	at	at	IN
cord-022561-rv5j1201	1882	26	the	the	DT
cord-022561-rv5j1201	1882	27	same	same	JJ
cord-022561-rv5j1201	1882	28	location	location	NN
cord-022561-rv5j1201	1882	29	and	and	CC
cord-022561-rv5j1201	1882	30	drains	drain	NNS
cord-022561-rv5j1201	1882	31	from	from	IN
cord-022561-rv5j1201	1882	32	the	the	DT
cord-022561-rv5j1201	1882	33	same	same	JJ
cord-022561-rv5j1201	1882	34	region	region	NN
cord-022561-rv5j1201	1882	35	in	in	IN
cord-022561-rv5j1201	1882	36	all	all	DT
cord-022561-rv5j1201	1882	37	species	specie	NNS
cord-022561-rv5j1201	1882	38	.	.	.
cord-022561-rv5j1201	1883	1	For	for	IN
cord-022561-rv5j1201	1883	2	example	example	NN
cord-022561-rv5j1201	1883	3	,	,	,
cord-022561-rv5j1201	1883	4	the	the	DT
cord-022561-rv5j1201	1883	5	popliteal	popliteal	JJ
cord-022561-rv5j1201	1883	6	lymph	lymph	NN
cord-022561-rv5j1201	1883	7	node	node	NN
cord-022561-rv5j1201	1883	8	,	,	,
cord-022561-rv5j1201	1883	9	caudal	caudal	JJ
cord-022561-rv5j1201	1883	10	to	to	IN
cord-022561-rv5j1201	1883	11	the	the	DT
cord-022561-rv5j1201	1883	12	stifle	stifle	NN
cord-022561-rv5j1201	1883	13	,	,	,
cord-022561-rv5j1201	1883	14	drains	drain	VBZ
cord-022561-rv5j1201	1883	15	the	the	DT
cord-022561-rv5j1201	1883	16	distal	distal	JJ
cord-022561-rv5j1201	1883	17	hind	hind	JJ
cord-022561-rv5j1201	1883	18	limb	limb	NN
cord-022561-rv5j1201	1883	19	.	.	.
cord-022561-rv5j1201	1884	1	The	the	DT
cord-022561-rv5j1201	1884	2	tracheobronchial	tracheobronchial	JJ
cord-022561-rv5j1201	1884	3	nodes	node	NNS
cord-022561-rv5j1201	1884	4	(	(	-LRB-
cord-022561-rv5j1201	1884	5	bronchial	bronchial	JJ
cord-022561-rv5j1201	1884	6	lymphocenter	lymphocenter	NN
cord-022561-rv5j1201	1884	7	)	)	-RRB-
cord-022561-rv5j1201	1884	8	,	,	,
cord-022561-rv5j1201	1884	9	located	locate	VBN
cord-022561-rv5j1201	1884	10	at	at	IN
cord-022561-rv5j1201	1884	11	the	the	DT
cord-022561-rv5j1201	1884	12	tracheal	tracheal	NN
cord-022561-rv5j1201	1884	13	bifurcation	bifurcation	NN
cord-022561-rv5j1201	1884	14	,	,	,
cord-022561-rv5j1201	1884	15	collect	collect	VB
cord-022561-rv5j1201	1884	16	lymph	lymph	NN
cord-022561-rv5j1201	1884	17	from	from	IN
cord-022561-rv5j1201	1884	18	the	the	DT
cord-022561-rv5j1201	1884	19	lungs	lung	NNS
cord-022561-rv5j1201	1884	20	and	and	CC
cord-022561-rv5j1201	1884	21	send	send	VB
cord-022561-rv5j1201	1884	22	it	-PRON-	PRP
cord-022561-rv5j1201	1884	23	to	to	IN
cord-022561-rv5j1201	1884	24	the	the	DT
cord-022561-rv5j1201	1884	25	mediastinal	mediastinal	JJ
cord-022561-rv5j1201	1884	26	nodes	node	NNS
cord-022561-rv5j1201	1884	27	or	or	CC
cord-022561-rv5j1201	1884	28	directly	directly	RB
cord-022561-rv5j1201	1884	29	to	to	IN
cord-022561-rv5j1201	1884	30	the	the	DT
cord-022561-rv5j1201	1884	31	thoracic	thoracic	JJ
cord-022561-rv5j1201	1884	32	duct	duct	NN
cord-022561-rv5j1201	1884	33	.	.	.
cord-022561-rv5j1201	1885	1	Because	because	IN
cord-022561-rv5j1201	1885	2	lymph	lymph	NN
cord-022561-rv5j1201	1885	3	from	from	IN
cord-022561-rv5j1201	1885	4	a	a	DT
cord-022561-rv5j1201	1885	5	single	single	JJ
cord-022561-rv5j1201	1885	6	afferent	afferent	JJ
cord-022561-rv5j1201	1885	7	lymphatic	lymphatic	NN
cord-022561-rv5j1201	1885	8	vessel	vessel	NN
cord-022561-rv5j1201	1885	9	drains	drain	VBZ
cord-022561-rv5j1201	1885	10	into	into	IN
cord-022561-rv5j1201	1885	11	a	a	DT
cord-022561-rv5j1201	1885	12	discrete	discrete	JJ
cord-022561-rv5j1201	1885	13	region	region	NN
cord-022561-rv5j1201	1885	14	of	of	IN
cord-022561-rv5j1201	1885	15	a	a	DT
cord-022561-rv5j1201	1885	16	lymph	lymph	NN
cord-022561-rv5j1201	1885	17	node	node	NN
cord-022561-rv5j1201	1885	18	,	,	,
cord-022561-rv5j1201	1885	19	only	only	RB
cord-022561-rv5j1201	1885	20	these	these	DT
cord-022561-rv5j1201	1885	21	regions	region	NNS
cord-022561-rv5j1201	1885	22	of	of	IN
cord-022561-rv5j1201	1885	23	the	the	DT
cord-022561-rv5j1201	1885	24	node	node	NN
cord-022561-rv5j1201	1885	25	may	may	MD
cord-022561-rv5j1201	1885	26	be	be	VB
cord-022561-rv5j1201	1885	27	affected	affect	VBN
cord-022561-rv5j1201	1885	28	by	by	IN
cord-022561-rv5j1201	1885	29	the	the	DT
cord-022561-rv5j1201	1885	30	contents	content	NNS
cord-022561-rv5j1201	1885	31	of	of	IN
cord-022561-rv5j1201	1885	32	a	a	DT
cord-022561-rv5j1201	1885	33	single	single	JJ
cord-022561-rv5j1201	1885	34	draining	drain	VBG
cord-022561-rv5j1201	1885	35	lymph	lymph	NN
cord-022561-rv5j1201	1885	36	vessel	vessel	NN
cord-022561-rv5j1201	1885	37	(	(	-LRB-
cord-022561-rv5j1201	1885	38	e.g.	e.g.	RB
cord-022561-rv5j1201	1885	39	,	,	,
cord-022561-rv5j1201	1885	40	antigen	antigen	NN
cord-022561-rv5j1201	1885	41	,	,	,
cord-022561-rv5j1201	1885	42	infectious	infectious	JJ
cord-022561-rv5j1201	1885	43	organisms	organism	NNS
cord-022561-rv5j1201	1885	44	,	,	,
cord-022561-rv5j1201	1885	45	or	or	CC
cord-022561-rv5j1201	1885	46	metastatic	metastatic	JJ
cord-022561-rv5j1201	1885	47	neoplasms	neoplasm	NNS
cord-022561-rv5j1201	1885	48	[	[	-LRB-
cord-022561-rv5j1201	1885	49	Fig	Fig	NNP
cord-022561-rv5j1201	1885	50	.	.	.
cord-022561-rv5j1201	1885	51	13	13	CD
cord-022561-rv5j1201	1885	52	-	-	SYM
cord-022561-rv5j1201	1885	53	47	47	CD
cord-022561-rv5j1201	1885	54	]	]	-RRB-
cord-022561-rv5j1201	1885	55	)	)	-RRB-
cord-022561-rv5j1201	1885	56	.	.	.
cord-022561-rv5j1201	1886	1	The	the	DT
cord-022561-rv5j1201	1886	2	lymph	lymph	NN
cord-022561-rv5j1201	1886	3	node	node	NN
cord-022561-rv5j1201	1886	4	of	of	IN
cord-022561-rv5j1201	1886	5	the	the	DT
cord-022561-rv5j1201	1886	6	pig	pig	NN
cord-022561-rv5j1201	1886	7	has	have	VBZ
cord-022561-rv5j1201	1886	8	a	a	DT
cord-022561-rv5j1201	1886	9	different	different	JJ
cord-022561-rv5j1201	1886	10	structure	structure	NN
cord-022561-rv5j1201	1886	11	.	.	.
cord-022561-rv5j1201	1887	1	The	the	DT
cord-022561-rv5j1201	1887	2	afferent	afferent	JJ
cord-022561-rv5j1201	1887	3	lymphatic	lymphatic	NN
cord-022561-rv5j1201	1887	4	vessels	vessel	NNS
cord-022561-rv5j1201	1887	5	enter	enter	VBP
cord-022561-rv5j1201	1887	6	at	at	IN
cord-022561-rv5j1201	1887	7	the	the	DT
cord-022561-rv5j1201	1887	8	hilus	hilus	NN
cord-022561-rv5j1201	1887	9	instead	instead	RB
cord-022561-rv5j1201	1887	10	of	of	IN
cord-022561-rv5j1201	1887	11	around	around	IN
cord-022561-rv5j1201	1887	12	the	the	DT
cord-022561-rv5j1201	1887	13	periphery	periphery	NN
cord-022561-rv5j1201	1887	14	of	of	IN
cord-022561-rv5j1201	1887	15	the	the	DT
cord-022561-rv5j1201	1887	16	node	node	NN
cord-022561-rv5j1201	1887	17	and	and	CC
cord-022561-rv5j1201	1887	18	empty	empty	JJ
cord-022561-rv5j1201	1887	19	lymph	lymph	NN
cord-022561-rv5j1201	1887	20	into	into	IN
cord-022561-rv5j1201	1887	21	the	the	DT
cord-022561-rv5j1201	1887	22	center	center	NN
cord-022561-rv5j1201	1887	23	of	of	IN
cord-022561-rv5j1201	1887	24	the	the	DT
cord-022561-rv5j1201	1887	25	node	node	NN
cord-022561-rv5j1201	1887	26	.	.	.
cord-022561-rv5j1201	1888	1	The	the	DT
cord-022561-rv5j1201	1888	2	lymph	lymph	NN
cord-022561-rv5j1201	1888	3	drains	drain	VBZ
cord-022561-rv5j1201	1888	4	to	to	IN
cord-022561-rv5j1201	1888	5	the	the	DT
cord-022561-rv5j1201	1888	6	"	"	``
cord-022561-rv5j1201	1888	7	subcapsular	subcapsular	JJ
cord-022561-rv5j1201	1888	8	"	"	''
cord-022561-rv5j1201	1888	9	sinus	sinus	NN
cord-022561-rv5j1201	1888	10	(	(	-LRB-
cord-022561-rv5j1201	1888	11	the	the	DT
cord-022561-rv5j1201	1888	12	equivalent	equivalent	NN
cord-022561-rv5j1201	1888	13	of	of	IN
cord-022561-rv5j1201	1888	14	the	the	DT
cord-022561-rv5j1201	1888	15	medullary	medullary	JJ
cord-022561-rv5j1201	1888	16	sinuses	sinus	NNS
cord-022561-rv5j1201	1888	17	of	of	IN
cord-022561-rv5j1201	1888	18	other	other	JJ
cord-022561-rv5j1201	1888	19	domestic	domestic	JJ
cord-022561-rv5j1201	1888	20	animals	animal	NNS
cord-022561-rv5j1201	1888	21	)	)	-RRB-
cord-022561-rv5j1201	1888	22	and	and	CC
cord-022561-rv5j1201	1888	23	then	then	RB
cord-022561-rv5j1201	1888	24	into	into	IN
cord-022561-rv5j1201	1888	25	several	several	JJ
cord-022561-rv5j1201	1888	26	efferent	efferent	JJ
cord-022561-rv5j1201	1888	27	lymphatic	lymphatic	JJ
cord-022561-rv5j1201	1888	28	vessels	vessel	NNS
cord-022561-rv5j1201	1888	29	,	,	,
cord-022561-rv5j1201	1888	30	which	which	WDT
cord-022561-rv5j1201	1888	31	pierce	pierce	VBP
cord-022561-rv5j1201	1888	32	the	the	DT
cord-022561-rv5j1201	1888	33	outer	outer	JJ
cord-022561-rv5j1201	1888	34	capsule	capsule	NN
cord-022561-rv5j1201	1888	35	.	.	.
cord-022561-rv5j1201	1889	1	This	this	DT
cord-022561-rv5j1201	1889	2	reversal	reversal	NN
cord-022561-rv5j1201	1889	3	of	of	IN
cord-022561-rv5j1201	1889	4	flow	flow	NN
cord-022561-rv5j1201	1889	5	is	be	VBZ
cord-022561-rv5j1201	1889	6	the	the	DT
cord-022561-rv5j1201	1889	7	result	result	NN
cord-022561-rv5j1201	1889	8	of	of	IN
cord-022561-rv5j1201	1889	9	an	an	DT
cord-022561-rv5j1201	1889	10	inverted	inverted	JJ
cord-022561-rv5j1201	1889	11	nodal	nodal	JJ
cord-022561-rv5j1201	1889	12	architecture	architecture	NN
cord-022561-rv5j1201	1889	13	,	,	,
cord-022561-rv5j1201	1889	14	with	with	IN
cord-022561-rv5j1201	1889	15	the	the	DT
cord-022561-rv5j1201	1889	16	cortex	cortex	NN
cord-022561-rv5j1201	1889	17	in	in	IN
cord-022561-rv5j1201	1889	18	the	the	DT
cord-022561-rv5j1201	1889	19	middle	middle	NN
cord-022561-rv5j1201	1889	20	of	of	IN
cord-022561-rv5j1201	1889	21	the	the	DT
cord-022561-rv5j1201	1889	22	node	node	NN
cord-022561-rv5j1201	1889	23	surrounded	surround	VBN
cord-022561-rv5j1201	1889	24	by	by	IN
cord-022561-rv5j1201	1889	25	the	the	DT
cord-022561-rv5j1201	1889	26	medulla	medulla	NN
cord-022561-rv5j1201	1889	27	at	at	IN
cord-022561-rv5j1201	1889	28	the	the	DT
cord-022561-rv5j1201	1889	29	periphery	periphery	NN
cord-022561-rv5j1201	1889	30	.	.	.
cord-022561-rv5j1201	1890	1	Thus	thus	RB
cord-022561-rv5j1201	1890	2	a	a	DT
cord-022561-rv5j1201	1890	3	pig	pig	NN
cord-022561-rv5j1201	1890	4	lymph	lymph	NN
cord-022561-rv5j1201	1890	5	node	node	NN
cord-022561-rv5j1201	1890	6	that	that	WDT
cord-022561-rv5j1201	1890	7	is	be	VBZ
cord-022561-rv5j1201	1890	8	draining	drain	VBG
cord-022561-rv5j1201	1890	9	an	an	DT
cord-022561-rv5j1201	1890	10	area	area	NN
cord-022561-rv5j1201	1890	11	of	of	IN
cord-022561-rv5j1201	1890	12	hemorrhage	hemorrhage	NN
cord-022561-rv5j1201	1890	13	will	will	MD
cord-022561-rv5j1201	1890	14	have	have	VB
cord-022561-rv5j1201	1890	15	blood	blood	NN
cord-022561-rv5j1201	1890	16	accumulate	accumulate	VB
cord-022561-rv5j1201	1890	17	in	in	IN
cord-022561-rv5j1201	1890	18	the	the	DT
cord-022561-rv5j1201	1890	19	periphery	periphery	NN
cord-022561-rv5j1201	1890	20	(	(	-LRB-
cord-022561-rv5j1201	1890	21	subcapsular	subcapsular	JJ
cord-022561-rv5j1201	1890	22	)	)	-RRB-
cord-022561-rv5j1201	1891	1	instead	instead	RB
cord-022561-rv5j1201	1891	2	of	of	IN
cord-022561-rv5j1201	1891	3	in	in	IN
cord-022561-rv5j1201	1891	4	the	the	DT
cord-022561-rv5j1201	1891	5	center	center	NN
cord-022561-rv5j1201	1891	6	of	of	IN
cord-022561-rv5j1201	1891	7	the	the	DT
cord-022561-rv5j1201	1891	8	node	node	NN
cord-022561-rv5j1201	1891	9	(	(	-LRB-
cord-022561-rv5j1201	1891	10	which	which	WDT
cord-022561-rv5j1201	1891	11	may	may	MD
cord-022561-rv5j1201	1891	12	be	be	VB
cord-022561-rv5j1201	1891	13	grossly	grossly	RB
cord-022561-rv5j1201	1891	14	visible	visible	JJ
cord-022561-rv5j1201	1891	15	)	)	-RRB-
cord-022561-rv5j1201	1891	16	.	.	.
cord-022561-rv5j1201	1892	1	The	the	DT
cord-022561-rv5j1201	1892	2	functions	function	NNS
cord-022561-rv5j1201	1892	3	of	of	IN
cord-022561-rv5j1201	1892	4	the	the	DT
cord-022561-rv5j1201	1892	5	lymph	lymph	NN
cord-022561-rv5j1201	1892	6	node	node	NN
cord-022561-rv5j1201	1892	7	are	be	VBP
cord-022561-rv5j1201	1892	8	(	(	-LRB-
cord-022561-rv5j1201	1892	9	1	1	CD
cord-022561-rv5j1201	1892	10	)	)	-RRB-
cord-022561-rv5j1201	1892	11	to	to	TO
cord-022561-rv5j1201	1892	12	filter	filter	VB
cord-022561-rv5j1201	1892	13	lymph	lymph	NN
cord-022561-rv5j1201	1892	14	of	of	IN
cord-022561-rv5j1201	1892	15	particulate	particulate	NN
cord-022561-rv5j1201	1892	16	matter	matter	NN
cord-022561-rv5j1201	1892	17	and	and	CC
cord-022561-rv5j1201	1892	18	microorganisms	microorganism	NNS
cord-022561-rv5j1201	1892	19	,	,	,
cord-022561-rv5j1201	1892	20	(	(	-LRB-
cord-022561-rv5j1201	1892	21	2	2	LS
cord-022561-rv5j1201	1892	22	)	)	-RRB-
cord-022561-rv5j1201	1892	23	to	to	TO
cord-022561-rv5j1201	1892	24	facilitate	facilitate	VB
cord-022561-rv5j1201	1892	25	the	the	DT
cord-022561-rv5j1201	1892	26	surveillance	surveillance	NN
cord-022561-rv5j1201	1892	27	and	and	CC
cord-022561-rv5j1201	1892	28	processing	processing	NN
cord-022561-rv5j1201	1892	29	of	of	IN
cord-022561-rv5j1201	1892	30	incoming	incoming	JJ
cord-022561-rv5j1201	1892	31	antigens	antigen	NNS
cord-022561-rv5j1201	1892	32	via	via	IN
cord-022561-rv5j1201	1892	33	interactions	interaction	NNS
cord-022561-rv5j1201	1892	34	with	with	IN
cord-022561-rv5j1201	1892	35	B	b	NN
cord-022561-rv5j1201	1892	36	and	and	CC
cord-022561-rv5j1201	1892	37	T	t	NN
cord-022561-rv5j1201	1892	38	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	1892	39	,	,	,
cord-022561-rv5j1201	1892	40	and	and	CC
cord-022561-rv5j1201	1892	41	(	(	-LRB-
cord-022561-rv5j1201	1892	42	3	3	LS
cord-022561-rv5j1201	1892	43	)	)	-RRB-
cord-022561-rv5j1201	1892	44	to	to	TO
cord-022561-rv5j1201	1892	45	produce	produce	VB
cord-022561-rv5j1201	1892	46	B	b	NN
cord-022561-rv5j1201	1892	47	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	1892	48	and	and	CC
cord-022561-rv5j1201	1892	49	plasma	plasma	NN
cord-022561-rv5j1201	1892	50	cells	cell	NNS
cord-022561-rv5j1201	1892	51	.	.	.
cord-022561-rv5j1201	1893	1	Material	material	NN
cord-022561-rv5j1201	1893	2	arriving	arrive	VBG
cord-022561-rv5j1201	1893	3	in	in	IN
cord-022561-rv5j1201	1893	4	the	the	DT
cord-022561-rv5j1201	1893	5	lymph	lymph	NN
cord-022561-rv5j1201	1893	6	can	can	MD
cord-022561-rv5j1201	1893	7	be	be	VB
cord-022561-rv5j1201	1893	8	subdivided	subdivide	VBN
cord-022561-rv5j1201	1893	9	into	into	IN
cord-022561-rv5j1201	1893	10	free	free	JJ
cord-022561-rv5j1201	1893	11	particles	particle	NNS
cord-022561-rv5j1201	1893	12	that	that	WDT
cord-022561-rv5j1201	1893	13	is	be	VBZ
cord-022561-rv5j1201	1893	14	undergoing	undergo	VBG
cord-022561-rv5j1201	1893	15	follicular	follicular	JJ
cord-022561-rv5j1201	1893	16	hyperplasia	hyperplasia	NN
cord-022561-rv5j1201	1893	17	is	be	VBZ
cord-022561-rv5j1201	1893	18	enlarged	enlarge	VBN
cord-022561-rv5j1201	1893	19	and	and	CC
cord-022561-rv5j1201	1893	20	has	have	VBZ
cord-022561-rv5j1201	1893	21	a	a	DT
cord-022561-rv5j1201	1893	22	taut	taut	JJ
cord-022561-rv5j1201	1893	23	capsule	capsule	NN
cord-022561-rv5j1201	1893	24	,	,	,
cord-022561-rv5j1201	1893	25	and	and	CC
cord-022561-rv5j1201	1893	26	the	the	DT
cord-022561-rv5j1201	1893	27	cut	cut	NN
cord-022561-rv5j1201	1893	28	surface	surface	NN
cord-022561-rv5j1201	1893	29	may	may	MD
cord-022561-rv5j1201	1893	30	bulge	bulge	VB
cord-022561-rv5j1201	1893	31	.	.	.
cord-022561-rv5j1201	1894	1	Histologically	histologically	RB
cord-022561-rv5j1201	1894	2	,	,	,
cord-022561-rv5j1201	1894	3	the	the	DT
cord-022561-rv5j1201	1894	4	follicles	follicle	NNS
cord-022561-rv5j1201	1894	5	contain	contain	VBP
cord-022561-rv5j1201	1894	6	active	active	JJ
cord-022561-rv5j1201	1894	7	germinal	germinal	JJ
cord-022561-rv5j1201	1894	8	centers	center	NNS
cord-022561-rv5j1201	1894	9	with	with	IN
cord-022561-rv5j1201	1894	10	antigenic	antigenic	JJ
cord-022561-rv5j1201	1894	11	polarity	polarity	NN
cord-022561-rv5j1201	1894	12	(	(	-LRB-
cord-022561-rv5j1201	1894	13	light	light	NN
cord-022561-rv5j1201	1894	14	and	and	CC
cord-022561-rv5j1201	1894	15	dark	dark	JJ
cord-022561-rv5j1201	1894	16	zones	zone	NNS
cord-022561-rv5j1201	1894	17	)	)	-RRB-
cord-022561-rv5j1201	1895	1	(	(	-LRB-
cord-022561-rv5j1201	1895	2	Figs	fig	NNS
cord-022561-rv5j1201	1895	3	.	.	.
cord-022561-rv5j1201	1896	1	13	13	CD
cord-022561-rv5j1201	1896	2	-	-	SYM
cord-022561-rv5j1201	1896	3	49	49	CD
cord-022561-rv5j1201	1896	4	and	and	CC
cord-022561-rv5j1201	1896	5	13	13	CD
cord-022561-rv5j1201	1896	6	-	-	SYM
cord-022561-rv5j1201	1896	7	50	50	CD
cord-022561-rv5j1201	1896	8	;	;	:
cord-022561-rv5j1201	1896	9	also	also	RB
cord-022561-rv5j1201	1896	10	see	see	VB
cord-022561-rv5j1201	1896	11	Fig	Fig	NNP
cord-022561-rv5j1201	1896	12	.	.	.
cord-022561-rv5j1201	1897	1	13	13	CD
cord-022561-rv5j1201	1897	2	-	-	SYM
cord-022561-rv5j1201	1897	3	46	46	CD
cord-022561-rv5j1201	1897	4	)	)	-RRB-
cord-022561-rv5j1201	1897	5	.	.	.
cord-022561-rv5j1201	1898	1	Depending	depend	VBG
cord-022561-rv5j1201	1898	2	on	on	IN
cord-022561-rv5j1201	1898	3	the	the	DT
cord-022561-rv5j1201	1898	4	duration	duration	NN
cord-022561-rv5j1201	1898	5	and	and	CC
cord-022561-rv5j1201	1898	6	continued	continue	VBN
cord-022561-rv5j1201	1898	7	exposure	exposure	NN
cord-022561-rv5j1201	1898	8	to	to	IN
cord-022561-rv5j1201	1898	9	the	the	DT
cord-022561-rv5j1201	1898	10	antigen	antigen	NN
cord-022561-rv5j1201	1898	11	,	,	,
cord-022561-rv5j1201	1898	12	there	there	EX
cord-022561-rv5j1201	1898	13	may	may	MD
cord-022561-rv5j1201	1898	14	also	also	RB
cord-022561-rv5j1201	1898	15	be	be	VB
cord-022561-rv5j1201	1898	16	concomitant	concomitant	JJ
cord-022561-rv5j1201	1898	17	paracortical	paracortical	JJ
cord-022561-rv5j1201	1898	18	hyperplasia	hyperplasia	NN
cord-022561-rv5j1201	1898	19	and	and	CC
cord-022561-rv5j1201	1898	20	medullary	medullary	JJ
cord-022561-rv5j1201	1898	21	cord	cord	NN
cord-022561-rv5j1201	1898	22	hyperplasia	hyperplasia	NN
cord-022561-rv5j1201	1898	23	and	and	CC
cord-022561-rv5j1201	1898	24	sinus	sinus	NNP
cord-022561-rv5j1201	1898	25	histiocytosis	histiocytosis	NN
cord-022561-rv5j1201	1898	26	,	,	,
cord-022561-rv5j1201	1898	27	because	because	IN
cord-022561-rv5j1201	1898	28	these	these	DT
cord-022561-rv5j1201	1898	29	nodes	node	NNS
cord-022561-rv5j1201	1898	30	continuously	continuously	RB
cord-022561-rv5j1201	1898	31	receive	receive	VBP
cord-022561-rv5j1201	1898	32	and	and	CC
cord-022561-rv5j1201	1898	33	respond	respond	VB
cord-022561-rv5j1201	1898	34	to	to	IN
cord-022561-rv5j1201	1898	35	barrages	barrage	NNS
cord-022561-rv5j1201	1898	36	of	of	IN
cord-022561-rv5j1201	1898	37	antigens	antigen	NNS
cord-022561-rv5j1201	1898	38	and	and	CC
cord-022561-rv5j1201	1898	39	bacteria	bacteria	NNS
cord-022561-rv5j1201	1898	40	from	from	IN
cord-022561-rv5j1201	1898	41	the	the	DT
cord-022561-rv5j1201	1898	42	intestinal	intestinal	JJ
cord-022561-rv5j1201	1898	43	tract	tract	NN
cord-022561-rv5j1201	1898	44	.	.	.
cord-022561-rv5j1201	1899	1	Sinus	Sinus	NNP
cord-022561-rv5j1201	1899	2	histiocytes	histiocyte	NNS
cord-022561-rv5j1201	1899	3	(	(	-LRB-
cord-022561-rv5j1201	1899	4	macrophages	macrophage	NNS
cord-022561-rv5j1201	1899	5	)	)	-RRB-
cord-022561-rv5j1201	1899	6	are	be	VBP
cord-022561-rv5j1201	1899	7	part	part	NN
cord-022561-rv5j1201	1899	8	of	of	IN
cord-022561-rv5j1201	1899	9	the	the	DT
cord-022561-rv5j1201	1899	10	monocyte	monocyte	JJ
cord-022561-rv5j1201	1899	11	-	-	HYPH
cord-022561-rv5j1201	1899	12	macrophage	macrophage	NN
cord-022561-rv5j1201	1899	13	system	system	NN
cord-022561-rv5j1201	1899	14	and	and	CC
cord-022561-rv5j1201	1899	15	the	the	DT
cord-022561-rv5j1201	1899	16	first	first	JJ
cord-022561-rv5j1201	1899	17	line	line	NN
cord-022561-rv5j1201	1899	18	of	of	IN
cord-022561-rv5j1201	1899	19	defense	defense	NN
cord-022561-rv5j1201	1899	20	against	against	IN
cord-022561-rv5j1201	1899	21	infectious	infectious	JJ
cord-022561-rv5j1201	1899	22	and	and	CC
cord-022561-rv5j1201	1899	23	noninfectious	noninfectious	JJ
cord-022561-rv5j1201	1899	24	agents	agent	NNS
cord-022561-rv5j1201	1899	25	in	in	IN
cord-022561-rv5j1201	1899	26	the	the	DT
cord-022561-rv5j1201	1899	27	incoming	incoming	JJ
cord-022561-rv5j1201	1899	28	lymph	lymph	NN
cord-022561-rv5j1201	1899	29	.	.	.
cord-022561-rv5j1201	1900	1	In	in	IN
cord-022561-rv5j1201	1900	2	response	response	NN
cord-022561-rv5j1201	1900	3	to	to	IN
cord-022561-rv5j1201	1900	4	these	these	DT
cord-022561-rv5j1201	1900	5	draining	drain	VBG
cord-022561-rv5j1201	1900	6	agents	agent	NNS
cord-022561-rv5j1201	1900	7	,	,	,
cord-022561-rv5j1201	1900	8	there	there	EX
cord-022561-rv5j1201	1900	9	is	be	VBZ
cord-022561-rv5j1201	1900	10	hyperplasia	hyperplasia	NN
cord-022561-rv5j1201	1900	11	of	of	IN
cord-022561-rv5j1201	1900	12	the	the	DT
cord-022561-rv5j1201	1900	13	macrophages	macrophage	NNS
cord-022561-rv5j1201	1900	14	(	(	-LRB-
cord-022561-rv5j1201	1900	15	"	"	``
cord-022561-rv5j1201	1900	16	sinus	sinus	NNP
cord-022561-rv5j1201	1900	17	histiocytosis	histiocytosis	NN
cord-022561-rv5j1201	1900	18	"	"	''
cord-022561-rv5j1201	1900	19	)	)	-RRB-
cord-022561-rv5j1201	1900	20	,	,	,
cord-022561-rv5j1201	1900	21	most	most	RBS
cord-022561-rv5j1201	1900	22	notable	notable	JJ
cord-022561-rv5j1201	1900	23	in	in	IN
cord-022561-rv5j1201	1900	24	the	the	DT
cord-022561-rv5j1201	1900	25	medullary	medullary	JJ
cord-022561-rv5j1201	1900	26	sinuses	sinus	NNS
cord-022561-rv5j1201	1900	27	(	(	-LRB-
cord-022561-rv5j1201	1900	28	Fig	Fig	NNP
cord-022561-rv5j1201	1900	29	.	.	.
cord-022561-rv5j1201	1900	30	13	13	CD
cord-022561-rv5j1201	1900	31	-	-	SYM
cord-022561-rv5j1201	1900	32	48	48	CD
cord-022561-rv5j1201	1900	33	)	)	-RRB-
cord-022561-rv5j1201	1900	34	.	.	.
cord-022561-rv5j1201	1901	1	Leukocytes	Leukocytes	NNP
cord-022561-rv5j1201	1901	2	,	,	,
cord-022561-rv5j1201	1901	3	often	often	RB
cord-022561-rv5j1201	1901	4	monocytes	monocyte	VBZ
cord-022561-rv5j1201	1901	5	,	,	,
cord-022561-rv5j1201	1901	6	may	may	MD
cord-022561-rv5j1201	1901	7	harbor	harbor	VB
cord-022561-rv5j1201	1901	8	intracellular	intracellular	JJ
cord-022561-rv5j1201	1901	9	pathogens	pathogen	NNS
cord-022561-rv5j1201	1901	10	(	(	-LRB-
cord-022561-rv5j1201	1901	11	e.g.	e.g.	RB
cord-022561-rv5j1201	1901	12	,	,	,
cord-022561-rv5j1201	1901	13	Mycobacterium	Mycobacterium	NNP
cord-022561-rv5j1201	1901	14	spp	spp	NNS
cord-022561-rv5j1201	1901	15	.	.	.
cord-022561-rv5j1201	1902	1	,	,	,
cord-022561-rv5j1201	1902	2	cell	cell	NN
cord-022561-rv5j1201	1902	3	-	-	HYPH
cord-022561-rv5j1201	1902	4	associated	associate	VBN
cord-022561-rv5j1201	1902	5	viruses	virus	NNS
cord-022561-rv5j1201	1902	6	such	such	JJ
cord-022561-rv5j1201	1902	7	as	as	IN
cord-022561-rv5j1201	1902	8	parvovirus	parvovirus	NN
cord-022561-rv5j1201	1902	9	)	)	-RRB-
cord-022561-rv5j1201	1902	10	,	,	,
cord-022561-rv5j1201	1902	11	arrive	arrive	VBP
cord-022561-rv5j1201	1902	12	in	in	IN
cord-022561-rv5j1201	1902	13	the	the	DT
cord-022561-rv5j1201	1902	14	blood	blood	NN
cord-022561-rv5j1201	1902	15	or	or	CC
cord-022561-rv5j1201	1902	16	lymph	lymph	NN
cord-022561-rv5j1201	1902	17	,	,	,
cord-022561-rv5j1201	1902	18	infect	infect	VB
cord-022561-rv5j1201	1902	19	the	the	DT
cord-022561-rv5j1201	1902	20	lymph	lymph	NN
cord-022561-rv5j1201	1902	21	node	node	NN
cord-022561-rv5j1201	1902	22	,	,	,
cord-022561-rv5j1201	1902	23	and	and	CC
cord-022561-rv5j1201	1902	24	then	then	RB
cord-022561-rv5j1201	1902	25	are	be	VBP
cord-022561-rv5j1201	1902	26	disseminated	disseminate	VBN
cord-022561-rv5j1201	1902	27	throughout	throughout	IN
cord-022561-rv5j1201	1902	28	the	the	DT
cord-022561-rv5j1201	1902	29	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	1902	30	tissues	tissue	NNS
cord-022561-rv5j1201	1902	31	of	of	IN
cord-022561-rv5j1201	1902	32	the	the	DT
cord-022561-rv5j1201	1902	33	body	body	NN
cord-022561-rv5j1201	1902	34	via	via	IN
cord-022561-rv5j1201	1902	35	the	the	DT
cord-022561-rv5j1201	1902	36	efferent	efferent	JJ
cord-022561-rv5j1201	1902	37	lymph	lymph	NN
cord-022561-rv5j1201	1902	38	and	and	CC
cord-022561-rv5j1201	1902	39	circulating	circulate	VBG
cord-022561-rv5j1201	1902	40	blood	blood	NN
cord-022561-rv5j1201	1902	41	.	.	.
cord-022561-rv5j1201	1903	1	Cortex	Cortex	NNP
cord-022561-rv5j1201	1903	2	(	(	-LRB-
cord-022561-rv5j1201	1903	3	Lymphoid	Lymphoid	NNP
cord-022561-rv5j1201	1903	4	Follicles	Follicles	NNPS
cord-022561-rv5j1201	1903	5	)	)	-RRB-
cord-022561-rv5j1201	1903	6	.	.	.
cord-022561-rv5j1201	1904	1	Follicular	follicular	JJ
cord-022561-rv5j1201	1904	2	hyperplasia	hyperplasia	NN
cord-022561-rv5j1201	1904	3	of	of	IN
cord-022561-rv5j1201	1904	4	the	the	DT
cord-022561-rv5j1201	1904	5	cortex	cortex	NN
cord-022561-rv5j1201	1904	6	is	be	VBZ
cord-022561-rv5j1201	1904	7	discussed	discuss	VBN
cord-022561-rv5j1201	1904	8	in	in	IN
cord-022561-rv5j1201	1904	9	the	the	DT
cord-022561-rv5j1201	1904	10	section	section	NN
cord-022561-rv5j1201	1905	1	Lymphoid	lymphoid	JJ
cord-022561-rv5j1201	1905	2	/	/	SYM
cord-022561-rv5j1201	1905	3	Lymphatic	Lymphatic	NNP
cord-022561-rv5j1201	1905	4	System	System	NNP
cord-022561-rv5j1201	1905	5	,	,	,
cord-022561-rv5j1201	1905	6	Lymph	Lymph	NNP
cord-022561-rv5j1201	1905	7	Node	Node	NNP
cord-022561-rv5j1201	1905	8	,	,	,
cord-022561-rv5j1201	1905	9	Function	function	NN
cord-022561-rv5j1201	1905	10	.	.	.
cord-022561-rv5j1201	1906	1	An	an	DT
cord-022561-rv5j1201	1906	2	antigenically	antigenically	RB
cord-022561-rv5j1201	1906	3	stimulated	stimulate	VBN
cord-022561-rv5j1201	1906	4	lymph	lymph	NN
cord-022561-rv5j1201	1906	5	node	node	NN
cord-022561-rv5j1201	1906	6	 	 	_SP
cord-022561-rv5j1201	1906	7	The	the	DT
cord-022561-rv5j1201	1906	8	two	two	CD
cord-022561-rv5j1201	1906	9	main	main	JJ
cord-022561-rv5j1201	1906	10	portals	portal	NNS
cord-022561-rv5j1201	1906	11	of	of	IN
cord-022561-rv5j1201	1906	12	entry	entry	NN
cord-022561-rv5j1201	1906	13	to	to	IN
cord-022561-rv5j1201	1906	14	the	the	DT
cord-022561-rv5j1201	1906	15	lymph	lymph	NN
cord-022561-rv5j1201	1906	16	node	node	NN
cord-022561-rv5j1201	1906	17	for	for	IN
cord-022561-rv5j1201	1906	18	infectious	infectious	JJ
cord-022561-rv5j1201	1906	19	agents	agent	NNS
cord-022561-rv5j1201	1906	20	and	and	CC
cord-022561-rv5j1201	1906	21	antigens	antigen	NNS
cord-022561-rv5j1201	1906	22	are	be	VBP
cord-022561-rv5j1201	1906	23	afferent	afferent	JJ
cord-022561-rv5j1201	1906	24	lymphatic	lymphatic	JJ
cord-022561-rv5j1201	1906	25	vessels	vessel	NNS
cord-022561-rv5j1201	1906	26	(	(	-LRB-
cord-022561-rv5j1201	1906	27	lymphatic	lymphatic	JJ
cord-022561-rv5j1201	1906	28	spread	spread	NN
cord-022561-rv5j1201	1906	29	)	)	-RRB-
cord-022561-rv5j1201	1906	30	and	and	CC
cord-022561-rv5j1201	1906	31	blood	blood	NN
cord-022561-rv5j1201	1906	32	vessels	vessel	NNS
cord-022561-rv5j1201	1906	33	(	(	-LRB-
cord-022561-rv5j1201	1906	34	hematogenous	hematogenous	NNP
cord-022561-rv5j1201	1906	35	spread	spread	NNP
cord-022561-rv5j1201	1906	36	)	)	-RRB-
cord-022561-rv5j1201	1906	37	.	.	.
cord-022561-rv5j1201	1907	1	Portals	portal	NNS
cord-022561-rv5j1201	1907	2	of	of	IN
cord-022561-rv5j1201	1907	3	entry	entry	NN
cord-022561-rv5j1201	1907	4	used	use	VBN
cord-022561-rv5j1201	1907	5	by	by	IN
cord-022561-rv5j1201	1907	6	microorganisms	microorganism	NNS
cord-022561-rv5j1201	1907	7	and	and	CC
cord-022561-rv5j1201	1907	8	other	other	JJ
cord-022561-rv5j1201	1907	9	agents	agent	NNS
cord-022561-rv5j1201	1907	10	and	and	CC
cord-022561-rv5j1201	1907	11	substances	substance	NNS
cord-022561-rv5j1201	1907	12	to	to	TO
cord-022561-rv5j1201	1907	13	access	access	VB
cord-022561-rv5j1201	1907	14	the	the	DT
cord-022561-rv5j1201	1907	15	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	1907	16	/	/	SYM
cord-022561-rv5j1201	1907	17	lymphatic	lymphatic	NN
cord-022561-rv5j1201	1907	18	system	system	NN
cord-022561-rv5j1201	1907	19	are	be	VBP
cord-022561-rv5j1201	1907	20	summarized	summarize	VBN
cord-022561-rv5j1201	1907	21	in	in	IN
cord-022561-rv5j1201	1907	22	Box	Box	NNP
cord-022561-rv5j1201	1907	23	13	13	CD
cord-022561-rv5j1201	1907	24	-	-	SYM
cord-022561-rv5j1201	1907	25	6	6	CD
cord-022561-rv5j1201	1907	26	.	.	.
cord-022561-rv5j1201	1908	1	Infectious	infectious	JJ
cord-022561-rv5j1201	1908	2	microorganisms	microorganism	NNS
cord-022561-rv5j1201	1908	3	,	,	,
cord-022561-rv5j1201	1908	4	either	either	CC
cord-022561-rv5j1201	1908	5	free	free	JJ
cord-022561-rv5j1201	1908	6	within	within	IN
cord-022561-rv5j1201	1908	7	the	the	DT
cord-022561-rv5j1201	1908	8	lymph	lymph	NN
cord-022561-rv5j1201	1908	9	or	or	CC
cord-022561-rv5j1201	1908	10	within	within	IN
cord-022561-rv5j1201	1908	11	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	1908	12	or	or	CC
cord-022561-rv5j1201	1908	13	monocytes	monocyte	NNS
cord-022561-rv5j1201	1908	14	,	,	,
cord-022561-rv5j1201	1908	15	are	be	VBP
cord-022561-rv5j1201	1908	16	transported	transport	VBN
cord-022561-rv5j1201	1908	17	to	to	IN
cord-022561-rv5j1201	1908	18	regional	regional	JJ
cord-022561-rv5j1201	1908	19	lymph	lymph	NN
cord-022561-rv5j1201	1908	20	nodes	node	NNS
cord-022561-rv5j1201	1908	21	through	through	IN
cord-022561-rv5j1201	1908	22	lymphatic	lymphatic	JJ
cord-022561-rv5j1201	1908	23	vessels	vessel	NNS
cord-022561-rv5j1201	1908	24	.	.	.
cord-022561-rv5j1201	1909	1	Agents	agent	NNS
cord-022561-rv5j1201	1909	2	may	may	MD
cord-022561-rv5j1201	1909	3	escape	escape	VB
cord-022561-rv5j1201	1909	4	removal	removal	NN
cord-022561-rv5j1201	1909	5	by	by	IN
cord-022561-rv5j1201	1909	6	phagocytosis	phagocytosis	NN
cord-022561-rv5j1201	1909	7	in	in	IN
cord-022561-rv5j1201	1909	8	one	one	CD
cord-022561-rv5j1201	1909	9	lymph	lymph	NN
cord-022561-rv5j1201	1909	10	node	node	NN
cord-022561-rv5j1201	1909	11	and	and	CC
cord-022561-rv5j1201	1909	12	be	be	VB
cord-022561-rv5j1201	1909	13	transported	transport	VBN
cord-022561-rv5j1201	1909	14	via	via	IN
cord-022561-rv5j1201	1909	15	efferent	efferent	JJ
cord-022561-rv5j1201	1909	16	lymphatic	lymphatic	JJ
cord-022561-rv5j1201	1909	17	vessels	vessel	NNS
cord-022561-rv5j1201	1909	18	to	to	IN
cord-022561-rv5j1201	1909	19	the	the	DT
cord-022561-rv5j1201	1909	20	next	next	JJ
cord-022561-rv5j1201	1909	21	lymph	lymph	NN
cord-022561-rv5j1201	1909	22	node	node	NN
cord-022561-rv5j1201	1909	23	in	in	IN
cord-022561-rv5j1201	1909	24	the	the	DT
cord-022561-rv5j1201	1909	25	chain	chain	NN
cord-022561-rv5j1201	1909	26	and	and	CC
cord-022561-rv5j1201	1909	27	cause	cause	VB
cord-022561-rv5j1201	1909	28	an	an	DT
cord-022561-rv5j1201	1909	29	inflammatory	inflammatory	JJ
cord-022561-rv5j1201	1909	30	or	or	CC
cord-022561-rv5j1201	1909	31	immunologic	immunologic	JJ
cord-022561-rv5j1201	1909	32	response	response	NN
cord-022561-rv5j1201	1909	33	there	there	RB
cord-022561-rv5j1201	1909	34	.	.	.
cord-022561-rv5j1201	1910	1	This	this	DT
cord-022561-rv5j1201	1910	2	process	process	NN
cord-022561-rv5j1201	1910	3	can	can	MD
cord-022561-rv5j1201	1910	4	continue	continue	VB
cord-022561-rv5j1201	1910	5	serially	serially	RB
cord-022561-rv5j1201	1910	6	down	down	IN
cord-022561-rv5j1201	1910	7	a	a	DT
cord-022561-rv5j1201	1910	8	lymph	lymph	NN
cord-022561-rv5j1201	1910	9	node	node	NN
cord-022561-rv5j1201	1910	10	chain	chain	NN
cord-022561-rv5j1201	1910	11	,	,	,
cord-022561-rv5j1201	1910	12	and	and	CC
cord-022561-rv5j1201	1910	13	if	if	IN
cord-022561-rv5j1201	1910	14	the	the	DT
cord-022561-rv5j1201	1910	15	agent	agent	NN
cord-022561-rv5j1201	1910	16	is	be	VBZ
cord-022561-rv5j1201	1910	17	not	not	RB
cord-022561-rv5j1201	1910	18	removed	remove	VBN
cord-022561-rv5j1201	1910	19	,	,	,
cord-022561-rv5j1201	1910	20	it	-PRON-	PRP
cord-022561-rv5j1201	1910	21	may	may	MD
cord-022561-rv5j1201	1910	22	eventually	eventually	RB
cord-022561-rv5j1201	1910	23	be	be	VB
cord-022561-rv5j1201	1910	24	transported	transport	VBN
cord-022561-rv5j1201	1910	25	via	via	IN
cord-022561-rv5j1201	1910	26	the	the	DT
cord-022561-rv5j1201	1910	27	lymphatic	lymphatic	JJ
cord-022561-rv5j1201	1910	28	vessels	vessel	NNS
cord-022561-rv5j1201	1910	29	to	to	IN
cord-022561-rv5j1201	1910	30	either	either	CC
cord-022561-rv5j1201	1910	31	the	the	DT
cord-022561-rv5j1201	1910	32	cervical	cervical	JJ
cord-022561-rv5j1201	1910	33	or	or	CC
cord-022561-rv5j1201	1910	34	thoracic	thoracic	JJ
cord-022561-rv5j1201	1910	35	ducts	duct	NNS
cord-022561-rv5j1201	1910	36	and	and	CC
cord-022561-rv5j1201	1910	37	then	then	RB
cord-022561-rv5j1201	1910	38	disseminated	disseminate	VBN
cord-022561-rv5j1201	1910	39	throughout	throughout	IN
cord-022561-rv5j1201	1910	40	the	the	DT
cord-022561-rv5j1201	1910	41	body	body	NN
cord-022561-rv5j1201	1910	42	.	.	.
cord-022561-rv5j1201	1911	1	Although	although	IN
cord-022561-rv5j1201	1911	2	most	most	JJS
cord-022561-rv5j1201	1911	3	pathogens	pathogen	NNS
cord-022561-rv5j1201	1911	4	are	be	VBP
cord-022561-rv5j1201	1911	5	transported	transport	VBN
cord-022561-rv5j1201	1911	6	to	to	IN
cord-022561-rv5j1201	1911	7	lymph	lymph	NN
cord-022561-rv5j1201	1911	8	nodes	node	NNS
cord-022561-rv5j1201	1911	9	via	via	IN
cord-022561-rv5j1201	1911	10	afferent	afferent	JJ
cord-022561-rv5j1201	1911	11	lymphatic	lymphatic	JJ
cord-022561-rv5j1201	1911	12	vessels	vessel	NNS
cord-022561-rv5j1201	1911	13	,	,	,
cord-022561-rv5j1201	1911	14	bacteria	bacteria	NNS
cord-022561-rv5j1201	1911	15	can	can	MD
cord-022561-rv5j1201	1911	16	be	be	VB
cord-022561-rv5j1201	1911	17	transported	transport	VBN
cord-022561-rv5j1201	1911	18	to	to	IN
cord-022561-rv5j1201	1911	19	lymph	lymph	NN
cord-022561-rv5j1201	1911	20	nodes	node	NNS
cord-022561-rv5j1201	1911	21	hematogenously	hematogenously	NNP
cord-022561-rv5j1201	1911	22	(	(	-LRB-
cord-022561-rv5j1201	1911	23	free	free	JJ
cord-022561-rv5j1201	1911	24	or	or	CC
cord-022561-rv5j1201	1911	25	within	within	IN
cord-022561-rv5j1201	1911	26	leukocytes	leukocyte	NNS
cord-022561-rv5j1201	1911	27	such	such	JJ
cord-022561-rv5j1201	1911	28	as	as	IN
cord-022561-rv5j1201	1911	29	monocytes	monocyte	NNS
cord-022561-rv5j1201	1911	30	)	)	-RRB-
cord-022561-rv5j1201	1911	31	in	in	IN
cord-022561-rv5j1201	1911	32	septicemias	septicemias	NNP
cord-022561-rv5j1201	1911	33	and	and	CC
cord-022561-rv5j1201	1911	34	bacteremias	bacteremias	NNP
cord-022561-rv5j1201	1911	35	.	.	.
cord-022561-rv5j1201	1912	1	Direct	direct	JJ
cord-022561-rv5j1201	1912	2	penetration	penetration	NN
cord-022561-rv5j1201	1912	3	of	of	IN
cord-022561-rv5j1201	1912	4	a	a	DT
cord-022561-rv5j1201	1912	5	lymph	lymph	NN
cord-022561-rv5j1201	1912	6	node	node	NN
cord-022561-rv5j1201	1912	7	is	be	VBZ
cord-022561-rv5j1201	1912	8	uncommon	uncommon	JJ
cord-022561-rv5j1201	1912	9	,	,	,
cord-022561-rv5j1201	1912	10	because	because	IN
cord-022561-rv5j1201	1912	11	it	-PRON-	PRP
cord-022561-rv5j1201	1912	12	is	be	VBZ
cord-022561-rv5j1201	1912	13	protected	protect	VBN
cord-022561-rv5j1201	1912	14	by	by	IN
cord-022561-rv5j1201	1912	15	a	a	DT
cord-022561-rv5j1201	1912	16	thick	thick	JJ
cord-022561-rv5j1201	1912	17	fibrous	fibrous	JJ
cord-022561-rv5j1201	1912	18	capsule	capsule	NN
cord-022561-rv5j1201	1912	19	.	.	.
cord-022561-rv5j1201	1913	1	Occasionally	occasionally	RB
cord-022561-rv5j1201	1913	2	,	,	,
cord-022561-rv5j1201	1913	3	inflammatory	inflammatory	JJ
cord-022561-rv5j1201	1913	4	cells	cell	NNS
cord-022561-rv5j1201	1913	5	or	or	CC
cord-022561-rv5j1201	1913	6	neoplasms	neoplasm	NNS
cord-022561-rv5j1201	1913	7	can	can	MD
cord-022561-rv5j1201	1913	8	extend	extend	VB
cord-022561-rv5j1201	1913	9	directly	directly	RB
cord-022561-rv5j1201	1913	10	into	into	IN
cord-022561-rv5j1201	1913	11	nodal	nodal	JJ
cord-022561-rv5j1201	1913	12	parenchyma	parenchyma	NN
cord-022561-rv5j1201	1913	13	from	from	IN
cord-022561-rv5j1201	1913	14	adjacent	adjacent	JJ
cord-022561-rv5j1201	1913	15	tissues	tissue	NNS
cord-022561-rv5j1201	1913	16	.	.	.
cord-022561-rv5j1201	1914	1	Defense	defense	NN
cord-022561-rv5j1201	1914	2	mechanisms	mechanism	NNS
cord-022561-rv5j1201	1914	3	used	use	VBN
cord-022561-rv5j1201	1914	4	by	by	IN
cord-022561-rv5j1201	1914	5	the	the	DT
cord-022561-rv5j1201	1914	6	lymphatic	lymphatic	JJ
cord-022561-rv5j1201	1914	7	system	system	NN
cord-022561-rv5j1201	1914	8	to	to	TO
cord-022561-rv5j1201	1914	9	protect	protect	VB
cord-022561-rv5j1201	1914	10	itself	-PRON-	PRP
cord-022561-rv5j1201	1914	11	against	against	IN
cord-022561-rv5j1201	1914	12	microorganisms	microorganism	NNS
cord-022561-rv5j1201	1914	13	and	and	CC
cord-022561-rv5j1201	1914	14	other	other	JJ
cord-022561-rv5j1201	1914	15	agents	agent	NNS
cord-022561-rv5j1201	1914	16	are	be	VBP
cord-022561-rv5j1201	1914	17	the	the	DT
cord-022561-rv5j1201	1914	18	innate	innate	JJ
cord-022561-rv5j1201	1914	19	and	and	CC
cord-022561-rv5j1201	1914	20	adaptive	adaptive	JJ
cord-022561-rv5j1201	1914	21	immune	immune	JJ
cord-022561-rv5j1201	1914	22	responses	response	NNS
cord-022561-rv5j1201	1914	23	,	,	,
cord-022561-rv5j1201	1914	24	discussed	discuss	VBN
cord-022561-rv5j1201	1914	25	in	in	IN
cord-022561-rv5j1201	1914	26	Chapters	chapter	NNS
cord-022561-rv5j1201	1914	27	3	3	CD
cord-022561-rv5j1201	1914	28	,	,	,
cord-022561-rv5j1201	1914	29	4	4	CD
cord-022561-rv5j1201	1914	30	,	,	,
cord-022561-rv5j1201	1914	31	and	and	CC
cord-022561-rv5j1201	1914	32	5	5	CD
cord-022561-rv5j1201	1914	33	.	.	.
cord-022561-rv5j1201	1915	1	Other	other	JJ
cord-022561-rv5j1201	1915	2	defense	defense	NN
cord-022561-rv5j1201	1915	3	mechanisms	mechanism	NNS
cord-022561-rv5j1201	1915	4	are	be	VBP
cord-022561-rv5j1201	1915	5	structural	structural	JJ
cord-022561-rv5j1201	1915	6	in	in	IN
cord-022561-rv5j1201	1915	7	nature	nature	NN
cord-022561-rv5j1201	1915	8	to	to	TO
cord-022561-rv5j1201	1915	9	protect	protect	VB
cord-022561-rv5j1201	1915	10	against	against	IN
cord-022561-rv5j1201	1915	11	external	external	JJ
cord-022561-rv5j1201	1915	12	trauma	trauma	NN
cord-022561-rv5j1201	1915	13	and	and	CC
cord-022561-rv5j1201	1915	14	include	include	VBP
cord-022561-rv5j1201	1915	15	the	the	DT
cord-022561-rv5j1201	1915	16	thick	thick	JJ
cord-022561-rv5j1201	1915	17	fibrous	fibrous	JJ
cord-022561-rv5j1201	1915	18	capsules	capsule	NNS
cord-022561-rv5j1201	1915	19	of	of	IN
cord-022561-rv5j1201	1915	20	lymph	lymph	NN
cord-022561-rv5j1201	1915	21	nodes	node	NNS
cord-022561-rv5j1201	1915	22	.	.	.
cord-022561-rv5j1201	1916	1	Hemal	Hemal	NNP
cord-022561-rv5j1201	1916	2	nodes	node	NNS
cord-022561-rv5j1201	1916	3	are	be	VBP
cord-022561-rv5j1201	1916	4	small	small	JJ
cord-022561-rv5j1201	1916	5	,	,	,
cord-022561-rv5j1201	1916	6	dark	dark	JJ
cord-022561-rv5j1201	1916	7	red	red	NN
cord-022561-rv5j1201	1916	8	to	to	IN
cord-022561-rv5j1201	1916	9	brown	brown	JJ
cord-022561-rv5j1201	1916	10	nodules	nodule	NNS
cord-022561-rv5j1201	1916	11	found	find	VBD
cord-022561-rv5j1201	1916	12	most	most	RBS
cord-022561-rv5j1201	1916	13	commonly	commonly	RB
cord-022561-rv5j1201	1916	14	in	in	IN
cord-022561-rv5j1201	1916	15	ruminants	ruminant	NNS
cord-022561-rv5j1201	1916	16	,	,	,
cord-022561-rv5j1201	1916	17	mainly	mainly	RB
cord-022561-rv5j1201	1916	18	sheep	sheep	NN
cord-022561-rv5j1201	1916	19	,	,	,
cord-022561-rv5j1201	1916	20	and	and	CC
cord-022561-rv5j1201	1916	21	have	have	VBP
cord-022561-rv5j1201	1916	22	also	also	RB
cord-022561-rv5j1201	1916	23	been	be	VBN
cord-022561-rv5j1201	1916	24	reported	report	VBN
cord-022561-rv5j1201	1916	25	in	in	IN
cord-022561-rv5j1201	1916	26	horses	horse	NNS
cord-022561-rv5j1201	1916	27	,	,	,
cord-022561-rv5j1201	1916	28	primates	primate	NNS
cord-022561-rv5j1201	1916	29	,	,	,
cord-022561-rv5j1201	1916	30	and	and	CC
cord-022561-rv5j1201	1916	31	some	some	DT
cord-022561-rv5j1201	1916	32	canids	canid	NNS
cord-022561-rv5j1201	1916	33	.	.	.
cord-022561-rv5j1201	1917	1	Their	-PRON-	PRP$
cord-022561-rv5j1201	1917	2	architecture	architecture	NN
cord-022561-rv5j1201	1917	3	resembles	resemble	VBZ
cord-022561-rv5j1201	1917	4	that	that	DT
cord-022561-rv5j1201	1917	5	of	of	IN
cord-022561-rv5j1201	1917	6	a	a	DT
cord-022561-rv5j1201	1917	7	lymph	lymph	NN
cord-022561-rv5j1201	1917	8	node	node	NN
cord-022561-rv5j1201	1917	9	with	with	IN
cord-022561-rv5j1201	1917	10	lymph	lymph	NN
cord-022561-rv5j1201	1917	11	follicles	follicle	NNS
cord-022561-rv5j1201	1917	12	and	and	CC
cord-022561-rv5j1201	1917	13	sinuses	sinus	NNS
cord-022561-rv5j1201	1917	14	,	,	,
cord-022561-rv5j1201	1917	15	except	except	IN
cord-022561-rv5j1201	1917	16	that	that	DT
cord-022561-rv5j1201	1917	17	in	in	IN
cord-022561-rv5j1201	1917	18	the	the	DT
cord-022561-rv5j1201	1917	19	hemal	hemal	NNP
cord-022561-rv5j1201	1917	20	node	node	NN
cord-022561-rv5j1201	1917	21	,	,	,
cord-022561-rv5j1201	1917	22	sinuses	sinus	NNS
cord-022561-rv5j1201	1917	23	are	be	VBP
cord-022561-rv5j1201	1917	24	filled	fill	VBN
cord-022561-rv5j1201	1917	25	with	with	IN
cord-022561-rv5j1201	1917	26	blood	blood	NN
cord-022561-rv5j1201	1917	27	(	(	-LRB-
cord-022561-rv5j1201	1917	28	E-	E-	NNP
cord-022561-rv5j1201	1917	29	Fig	Fig	NNP
cord-022561-rv5j1201	1917	30	.	.	.
cord-022561-rv5j1201	1918	1	13	13	CD
cord-022561-rv5j1201	1918	2	-	-	SYM
cord-022561-rv5j1201	1918	3	8	8	CD
cord-022561-rv5j1201	1918	4	)	)	-RRB-
cord-022561-rv5j1201	1918	5	.	.	.
cord-022561-rv5j1201	1919	1	Because	because	IN
cord-022561-rv5j1201	1919	2	erythrophagocytosis	erythrophagocytosis	NNP
cord-022561-rv5j1201	1919	3	can	can	MD
cord-022561-rv5j1201	1919	4	be	be	VB
cord-022561-rv5j1201	1919	5	present	present	JJ
cord-022561-rv5j1201	1919	6	,	,	,
cord-022561-rv5j1201	1919	7	it	-PRON-	PRP
cord-022561-rv5j1201	1919	8	is	be	VBZ
cord-022561-rv5j1201	1919	9	presumed	presume	VBN
cord-022561-rv5j1201	1919	10	that	that	IN
cord-022561-rv5j1201	1919	11	hemal	hemal	NNP
cord-022561-rv5j1201	1919	12	nodes	node	NNS
cord-022561-rv5j1201	1919	13	can	can	MD
cord-022561-rv5j1201	1919	14	filter	filter	VB
cord-022561-rv5j1201	1919	15	blood	blood	NN
cord-022561-rv5j1201	1919	16	and	and	CC
cord-022561-rv5j1201	1919	17	remove	remove	VB
cord-022561-rv5j1201	1919	18	senescent	senescent	JJ
cord-022561-rv5j1201	1919	19	erythrocytes	erythrocyte	NNS
cord-022561-rv5j1201	1919	20	,	,	,
cord-022561-rv5j1201	1919	21	but	but	CC
cord-022561-rv5j1201	1919	22	as	as	IN
cord-022561-rv5j1201	1919	23	their	-PRON-	PRP$
cord-022561-rv5j1201	1919	24	blood	blood	NN
cord-022561-rv5j1201	1919	25	supply	supply	NN
cord-022561-rv5j1201	1919	26	is	be	VBZ
cord-022561-rv5j1201	1919	27	small	small	JJ
cord-022561-rv5j1201	1919	28	,	,	,
cord-022561-rv5j1201	1919	29	their	-PRON-	PRP$
cord-022561-rv5j1201	1919	30	functional	functional	JJ
cord-022561-rv5j1201	1919	31	importance	importance	NN
cord-022561-rv5j1201	1919	32	is	be	VBZ
cord-022561-rv5j1201	1919	33	not	not	RB
cord-022561-rv5j1201	1919	34	clear	clear	JJ
cord-022561-rv5j1201	1919	35	.	.	.
cord-022561-rv5j1201	1920	1	MALT	malt	NN
cord-022561-rv5j1201	1920	2	is	be	VBZ
cord-022561-rv5j1201	1920	3	the	the	DT
cord-022561-rv5j1201	1920	4	initial	initial	JJ
cord-022561-rv5j1201	1920	5	site	site	NN
cord-022561-rv5j1201	1920	6	for	for	IN
cord-022561-rv5j1201	1920	7	mucosal	mucosal	JJ
cord-022561-rv5j1201	1920	8	immunity	immunity	NN
cord-022561-rv5j1201	1920	9	and	and	CC
cord-022561-rv5j1201	1920	10	is	be	VBZ
cord-022561-rv5j1201	1920	11	crucial	crucial	JJ
cord-022561-rv5j1201	1920	12	in	in	IN
cord-022561-rv5j1201	1920	13	the	the	DT
cord-022561-rv5j1201	1920	14	protection	protection	NN
cord-022561-rv5j1201	1920	15	of	of	IN
cord-022561-rv5j1201	1920	16	mucosal	mucosal	JJ
cord-022561-rv5j1201	1920	17	barriers	barrier	NNS
cord-022561-rv5j1201	1920	18	.	.	.
cord-022561-rv5j1201	1921	1	MALT	malt	NN
cord-022561-rv5j1201	1921	2	is	be	VBZ
cord-022561-rv5j1201	1921	3	composed	compose	VBN
cord-022561-rv5j1201	1921	4	of	of	IN
cord-022561-rv5j1201	1921	5	both	both	DT
cord-022561-rv5j1201	1921	6	diffuse	diffuse	JJ
cord-022561-rv5j1201	1921	7	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	1921	8	tissues	tissue	NNS
cord-022561-rv5j1201	1921	9	and	and	CC
cord-022561-rv5j1201	1921	10	aggregated	aggregated	JJ
cord-022561-rv5j1201	1921	11	lymphoid	lymphoid	NNS
cord-022561-rv5j1201	1921	12	(	(	-LRB-
cord-022561-rv5j1201	1921	13	also	also	RB
cord-022561-rv5j1201	1921	14	known	know	VBN
cord-022561-rv5j1201	1921	15	as	as	IN
cord-022561-rv5j1201	1921	16	lymphatic	lymphatic	NN
cord-022561-rv5j1201	1921	17	)	)	-RRB-
cord-022561-rv5j1201	1921	18	nodules	nodule	NNS
cord-022561-rv5j1201	1921	19	,	,	,
cord-022561-rv5j1201	1921	20	which	which	WDT
cord-022561-rv5j1201	1921	21	can	can	MD
cord-022561-rv5j1201	1921	22	be	be	VB
cord-022561-rv5j1201	1921	23	subcategorized	subcategorize	VBN
cord-022561-rv5j1201	1921	24	based	base	VBN
cord-022561-rv5j1201	1921	25	on	on	IN
cord-022561-rv5j1201	1921	26	their	-PRON-	PRP$
cord-022561-rv5j1201	1921	27	anatomic	anatomic	JJ
cord-022561-rv5j1201	1921	28	location	location	NN
cord-022561-rv5j1201	1921	29	:	:	:
cord-022561-rv5j1201	1922	1	(	(	-LRB-
cord-022561-rv5j1201	1922	2	1	1	LS
cord-022561-rv5j1201	1922	3	)	)	-RRB-
cord-022561-rv5j1201	1922	4	bronchus	bronchus	NN
cord-022561-rv5j1201	1922	5	-	-	HYPH
cord-022561-rv5j1201	1922	6	associated	associate	VBN
cord-022561-rv5j1201	1922	7	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	1922	8	tissue	tissue	NN
cord-022561-rv5j1201	1922	9	(	(	-LRB-
cord-022561-rv5j1201	1922	10	BALT	BALT	NNP
cord-022561-rv5j1201	1922	11	)	)	-RRB-
cord-022561-rv5j1201	1922	12	,	,	,
cord-022561-rv5j1201	1922	13	which	which	WDT
cord-022561-rv5j1201	1922	14	is	be	VBZ
cord-022561-rv5j1201	1922	15	often	often	RB
cord-022561-rv5j1201	1922	16	at	at	IN
cord-022561-rv5j1201	1922	17	the	the	DT
cord-022561-rv5j1201	1922	18	bifurcation	bifurcation	NN
cord-022561-rv5j1201	1922	19	of	of	IN
cord-022561-rv5j1201	1922	20	the	the	DT
cord-022561-rv5j1201	1922	21	bronchi	bronchi	NN
cord-022561-rv5j1201	1922	22	and	and	CC
cord-022561-rv5j1201	1922	23	bronchioles	bronchiole	NNS
cord-022561-rv5j1201	1922	24	;	;	,
cord-022561-rv5j1201	1922	25	(	(	-LRB-
cord-022561-rv5j1201	1922	26	2	2	LS
cord-022561-rv5j1201	1922	27	)	)	-RRB-
cord-022561-rv5j1201	1922	28	tonsils	tonsil	NNS
cord-022561-rv5j1201	1922	29	(	(	-LRB-
cord-022561-rv5j1201	1922	30	pharyngeal	pharyngeal	NNP
cord-022561-rv5j1201	1922	31	and	and	CC
cord-022561-rv5j1201	1922	32	palatine	palatine	NNP
cord-022561-rv5j1201	1922	33	)	)	-RRB-
cord-022561-rv5j1201	1922	34	form	form	VB
cord-022561-rv5j1201	1922	35	a	a	DT
cord-022561-rv5j1201	1922	36	ring	ring	NN
cord-022561-rv5j1201	1922	37	of	of	IN
cord-022561-rv5j1201	1922	38	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	1922	39	tissue	tissue	NN
cord-022561-rv5j1201	1922	40	at	at	IN
cord-022561-rv5j1201	1922	41	the	the	DT
cord-022561-rv5j1201	1922	42	oropharynx	oropharynx	NN
cord-022561-rv5j1201	1922	43	;	;	,
cord-022561-rv5j1201	1922	44	(	(	-LRB-
cord-022561-rv5j1201	1922	45	3	3	LS
cord-022561-rv5j1201	1922	46	)	)	-RRB-
cord-022561-rv5j1201	1922	47	nasal-	nasal-	NN
cord-022561-rv5j1201	1922	48	,	,	,
cord-022561-rv5j1201	1922	49	larynx-	larynx-	JJ
cord-022561-rv5j1201	1922	50	,	,	,
cord-022561-rv5j1201	1922	51	and	and	CC
cord-022561-rv5j1201	1922	52	auditory	auditory	JJ
cord-022561-rv5j1201	1922	53	tube	tube	NN
cord-022561-rv5j1201	1922	54	-	-	HYPH
cord-022561-rv5j1201	1922	55	associated	associate	VBN
cord-022561-rv5j1201	1922	56	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	1922	57	tissues	tissue	NNS
cord-022561-rv5j1201	1922	58	(	(	-LRB-
cord-022561-rv5j1201	1922	59	NALT	NALT	NNP
cord-022561-rv5j1201	1922	60	,	,	,
cord-022561-rv5j1201	1922	61	LALT	LALT	NNP
cord-022561-rv5j1201	1922	62	,	,	,
cord-022561-rv5j1201	1922	63	and	and	CC
cord-022561-rv5j1201	1922	64	ATALT	ATALT	NNP
cord-022561-rv5j1201	1922	65	,	,	,
cord-022561-rv5j1201	1922	66	respectively	respectively	RB
cord-022561-rv5j1201	1922	67	)	)	-RRB-
cord-022561-rv5j1201	1922	68	within	within	IN
cord-022561-rv5j1201	1922	69	the	the	DT
cord-022561-rv5j1201	1922	70	nasopharyngeal	nasopharyngeal	JJ
cord-022561-rv5j1201	1922	71	area	area	NN
cord-022561-rv5j1201	1922	72	;	;	,
cord-022561-rv5j1201	1922	73	(	(	-LRB-
cord-022561-rv5j1201	1922	74	4	4	LS
cord-022561-rv5j1201	1922	75	)	)	-RRB-
cord-022561-rv5j1201	1922	76	gut	gut	VB
cord-022561-rv5j1201	1922	77	-	-	HYPH
cord-022561-rv5j1201	1922	78	associated	associate	VBN
cord-022561-rv5j1201	1922	79	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	1922	80	tissue	tissue	NN
cord-022561-rv5j1201	1922	81	(	(	-LRB-
cord-022561-rv5j1201	1922	82	GALT	GALT	NNP
cord-022561-rv5j1201	1922	83	)	)	-RRB-
cord-022561-rv5j1201	1922	84	,	,	,
cord-022561-rv5j1201	1922	85	which	which	WDT
cord-022561-rv5j1201	1922	86	includes	include	VBZ
cord-022561-rv5j1201	1922	87	Peyer	Peyer	NNP
cord-022561-rv5j1201	1922	88	's	's	POS
cord-022561-rv5j1201	1922	89	patches	patch	NNS
cord-022561-rv5j1201	1922	90	and	and	CC
cord-022561-rv5j1201	1922	91	diffuse	diffuse	VB
cord-022561-rv5j1201	1922	92	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	1922	93	tissue	tissue	NN
cord-022561-rv5j1201	1922	94	in	in	IN
cord-022561-rv5j1201	1922	95	the	the	DT
cord-022561-rv5j1201	1922	96	gut	gut	NN
cord-022561-rv5j1201	1922	97	wall	wall	NN
cord-022561-rv5j1201	1922	98	;	;	:
cord-022561-rv5j1201	1922	99	(	(	-LRB-
cord-022561-rv5j1201	1922	100	5	5	LS
cord-022561-rv5j1201	1922	101	)	)	-RRB-
cord-022561-rv5j1201	1922	102	conjunctiva	conjunctiva	NN
cord-022561-rv5j1201	1922	103	-	-	HYPH
cord-022561-rv5j1201	1922	104	associated	associate	VBN
cord-022561-rv5j1201	1922	105	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	1922	106	tissue	tissue	NN
cord-022561-rv5j1201	1922	107	(	(	-LRB-
cord-022561-rv5j1201	1922	108	CALT	CALT	NNP
cord-022561-rv5j1201	1922	109	)	)	-RRB-
cord-022561-rv5j1201	1922	110	;	;	:
cord-022561-rv5j1201	1922	111	(	(	-LRB-
cord-022561-rv5j1201	1922	112	6	6	CD
cord-022561-rv5j1201	1922	113	)	)	-RRB-
cord-022561-rv5j1201	1922	114	other	other	JJ
cord-022561-rv5j1201	1922	115	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	1922	116	nodules	nodule	NNS
cord-022561-rv5j1201	1922	117	(	(	-LRB-
cord-022561-rv5j1201	1922	118	e.g.	e.g.	RB
cord-022561-rv5j1201	1922	119	,	,	,
cord-022561-rv5j1201	1922	120	genitourinary	genitourinary	JJ
cord-022561-rv5j1201	1922	121	tract	tract	NN
cord-022561-rv5j1201	1922	122	)	)	-RRB-
cord-022561-rv5j1201	1922	123	(	(	-LRB-
cord-022561-rv5j1201	1922	124	Fig	fig	NN
cord-022561-rv5j1201	1922	125	.	.	.
cord-022561-rv5j1201	1923	1	13	13	CD
cord-022561-rv5j1201	1923	2	-	-	SYM
cord-022561-rv5j1201	1923	3	51	51	CD
cord-022561-rv5j1201	1923	4	)	)	-RRB-
cord-022561-rv5j1201	1923	5	.	.	.
cord-022561-rv5j1201	1924	1	Diffuse	diffuse	JJ
cord-022561-rv5j1201	1924	2	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	1924	3	tissue	tissue	NN
cord-022561-rv5j1201	1924	4	consists	consist	VBZ
cord-022561-rv5j1201	1924	5	of	of	IN
cord-022561-rv5j1201	1924	6	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	1924	7	and	and	CC
cord-022561-rv5j1201	1924	8	DCs	dc	NNS
cord-022561-rv5j1201	1924	9	within	within	IN
cord-022561-rv5j1201	1924	10	the	the	DT
cord-022561-rv5j1201	1924	11	lamina	lamina	JJ
cord-022561-rv5j1201	1924	12	propria	propria	NN
cord-022561-rv5j1201	1924	13	of	of	IN
cord-022561-rv5j1201	1924	14	the	the	DT
cord-022561-rv5j1201	1924	15	mucosa	mucosa	NN
cord-022561-rv5j1201	1924	16	of	of	IN
cord-022561-rv5j1201	1924	17	the	the	DT
cord-022561-rv5j1201	1924	18	alimentary	alimentary	JJ
cord-022561-rv5j1201	1924	19	,	,	,
cord-022561-rv5j1201	1924	20	respiratory	respiratory	JJ
cord-022561-rv5j1201	1924	21	,	,	,
cord-022561-rv5j1201	1924	22	and	and	CC
cord-022561-rv5j1201	1924	23	genitourinary	genitourinary	JJ
cord-022561-rv5j1201	1924	24	tracts	tract	NNS
cord-022561-rv5j1201	1924	25	.	.	.
cord-022561-rv5j1201	1925	1	These	these	DT
cord-022561-rv5j1201	1925	2	cells	cell	NNS
cord-022561-rv5j1201	1925	3	intercept	intercept	VBP
cord-022561-rv5j1201	1925	4	and	and	CC
cord-022561-rv5j1201	1925	5	process	process	NN
cord-022561-rv5j1201	1925	6	antigens	antigen	NNS
cord-022561-rv5j1201	1925	7	,	,	,
cord-022561-rv5j1201	1925	8	which	which	WDT
cord-022561-rv5j1201	1925	9	then	then	RB
cord-022561-rv5j1201	1925	10	travel	travel	VBP
cord-022561-rv5j1201	1925	11	to	to	IN
cord-022561-rv5j1201	1925	12	regional	regional	JJ
cord-022561-rv5j1201	1925	13	lymph	lymph	NN
cord-022561-rv5j1201	1925	14	nodes	node	NNS
cord-022561-rv5j1201	1925	15	to	to	TO
cord-022561-rv5j1201	1925	16	initiate	initiate	VB
cord-022561-rv5j1201	1925	17	the	the	DT
cord-022561-rv5j1201	1925	18	immune	immune	JJ
cord-022561-rv5j1201	1925	19	response	response	NN
cord-022561-rv5j1201	1925	20	,	,	,
cord-022561-rv5j1201	1925	21	leading	lead	VBG
cord-022561-rv5j1201	1925	22	ultimately	ultimately	RB
cord-022561-rv5j1201	1925	23	to	to	IN
cord-022561-rv5j1201	1925	24	the	the	DT
cord-022561-rv5j1201	1925	25	secretion	secretion	NN
cord-022561-rv5j1201	1925	26	of	of	IN
cord-022561-rv5j1201	1925	27	IgA	IgA	NNP
cord-022561-rv5j1201	1925	28	,	,	,
cord-022561-rv5j1201	1925	29	IgG	IgG	NNP
cord-022561-rv5j1201	1925	30	,	,	,
cord-022561-rv5j1201	1925	31	and	and	CC
cord-022561-rv5j1201	1925	32	IgM.	IgM.	NNP
cord-022561-rv5j1201	1925	33	plasmacytosis	plasmacytosis	NNP
cord-022561-rv5j1201	1925	34	.	.	.
cord-022561-rv5j1201	1926	1	Less	less	RBR
cord-022561-rv5j1201	1926	2	florid	florid	JJ
cord-022561-rv5j1201	1926	3	follicular	follicular	JJ
cord-022561-rv5j1201	1926	4	reactions	reaction	NNS
cord-022561-rv5j1201	1926	5	will	will	MD
cord-022561-rv5j1201	1926	6	have	have	VB
cord-022561-rv5j1201	1926	7	smaller	small	JJR
cord-022561-rv5j1201	1926	8	separated	separate	VBN
cord-022561-rv5j1201	1926	9	germinal	germinal	JJ
cord-022561-rv5j1201	1926	10	centers	center	NNS
cord-022561-rv5j1201	1926	11	,	,	,
cord-022561-rv5j1201	1926	12	whereas	whereas	IN
cord-022561-rv5j1201	1926	13	nodes	node	NNS
cord-022561-rv5j1201	1926	14	receiving	receive	VBG
cord-022561-rv5j1201	1926	15	persistent	persistent	JJ
cord-022561-rv5j1201	1926	16	high	high	JJ
cord-022561-rv5j1201	1926	17	levels	level	NNS
cord-022561-rv5j1201	1926	18	of	of	IN
cord-022561-rv5j1201	1926	19	antigen	antigen	NN
cord-022561-rv5j1201	1926	20	stimulation	stimulation	NN
cord-022561-rv5j1201	1926	21	may	may	MD
cord-022561-rv5j1201	1926	22	have	have	VB
cord-022561-rv5j1201	1926	23	coalescing	coalesce	VBG
cord-022561-rv5j1201	1926	24	germinal	germinal	JJ
cord-022561-rv5j1201	1926	25	centers	center	NNS
cord-022561-rv5j1201	1926	26	(	(	-LRB-
cord-022561-rv5j1201	1926	27	termed	term	VBN
cord-022561-rv5j1201	1926	28	"	"	``
cord-022561-rv5j1201	1926	29	atypical	atypical	JJ
cord-022561-rv5j1201	1926	30	benign	benign	JJ
cord-022561-rv5j1201	1926	31	follicular	follicular	JJ
cord-022561-rv5j1201	1926	32	hyperplasia	hyperplasia	NN
cord-022561-rv5j1201	1926	33	"	"	''
cord-022561-rv5j1201	1926	34	)	)	-RRB-
cord-022561-rv5j1201	1926	35	.	.	.
cord-022561-rv5j1201	1927	1	In	in	IN
cord-022561-rv5j1201	1927	2	such	such	JJ
cord-022561-rv5j1201	1927	3	cases	case	NNS
cord-022561-rv5j1201	1927	4	of	of	IN
cord-022561-rv5j1201	1927	5	chronic	chronic	JJ
cord-022561-rv5j1201	1927	6	strong	strong	JJ
cord-022561-rv5j1201	1927	7	antigenemia	antigenemia	NN
cord-022561-rv5j1201	1927	8	,	,	,
cord-022561-rv5j1201	1927	9	the	the	DT
cord-022561-rv5j1201	1927	10	highly	highly	RB
cord-022561-rv5j1201	1927	11	reactive	reactive	JJ
cord-022561-rv5j1201	1927	12	nodes	node	NNS
cord-022561-rv5j1201	1927	13	may	may	MD
cord-022561-rv5j1201	1927	14	also	also	RB
cord-022561-rv5j1201	1927	15	exhibit	exhibit	VB
cord-022561-rv5j1201	1927	16	colonization	colonization	NN
cord-022561-rv5j1201	1927	17	of	of	IN
cord-022561-rv5j1201	1927	18	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	1927	19	into	into	IN
cord-022561-rv5j1201	1927	20	perinodal	perinodal	JJ
cord-022561-rv5j1201	1927	21	fat	fat	JJ
cord-022561-rv5j1201	1927	22	,	,	,
cord-022561-rv5j1201	1927	23	and	and	CC
cord-022561-rv5j1201	1927	24	germinal	germinal	JJ
cord-022561-rv5j1201	1927	25	centers	center	NNS
cord-022561-rv5j1201	1927	26	may	may	MD
cord-022561-rv5j1201	1927	27	contain	contain	VB
cord-022561-rv5j1201	1927	28	irregular	irregular	JJ
cord-022561-rv5j1201	1927	29	lakes	lake	NNS
cord-022561-rv5j1201	1927	30	of	of	IN
cord-022561-rv5j1201	1927	31	eosinophilic	eosinophilic	JJ
cord-022561-rv5j1201	1927	32	material	material	NN
cord-022561-rv5j1201	1927	33	,	,	,
cord-022561-rv5j1201	1927	34	known	know	VBN
cord-022561-rv5j1201	1927	35	as	as	IN
cord-022561-rv5j1201	1927	36	follicular	follicular	JJ
cord-022561-rv5j1201	1927	37	hyalinosis	hyalinosis	NN
cord-022561-rv5j1201	1927	38	.	.	.
cord-022561-rv5j1201	1928	1	As	as	IN
cord-022561-rv5j1201	1928	2	the	the	DT
cord-022561-rv5j1201	1928	3	immune	immune	JJ
cord-022561-rv5j1201	1928	4	response	response	NN
cord-022561-rv5j1201	1928	5	declines	decline	VBZ
cord-022561-rv5j1201	1928	6	,	,	,
cord-022561-rv5j1201	1928	7	there	there	EX
cord-022561-rv5j1201	1928	8	is	be	VBZ
cord-022561-rv5j1201	1928	9	follicular	follicular	JJ
cord-022561-rv5j1201	1928	10	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	1928	11	depletion	depletion	NN
cord-022561-rv5j1201	1928	12	and	and	CC
cord-022561-rv5j1201	1928	13	the	the	DT
cord-022561-rv5j1201	1928	14	concentration	concentration	NN
cord-022561-rv5j1201	1928	15	of	of	IN
cord-022561-rv5j1201	1928	16	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	1928	17	in	in	IN
cord-022561-rv5j1201	1928	18	the	the	DT
cord-022561-rv5j1201	1928	19	germinal	germinal	JJ
cord-022561-rv5j1201	1928	20	centers	center	NNS
cord-022561-rv5j1201	1928	21	is	be	VBZ
cord-022561-rv5j1201	1928	22	reduced	reduce	VBN
cord-022561-rv5j1201	1928	23	,	,	,
cord-022561-rv5j1201	1928	24	allowing	allow	VBG
cord-022561-rv5j1201	1928	25	the	the	DT
cord-022561-rv5j1201	1928	26	underlying	underlying	JJ
cord-022561-rv5j1201	1928	27	follicular	follicular	JJ
cord-022561-rv5j1201	1928	28	stroma	stroma	NN
cord-022561-rv5j1201	1928	29	(	(	-LRB-
cord-022561-rv5j1201	1928	30	including	include	VBG
cord-022561-rv5j1201	1928	31	DCs	dc	NNS
cord-022561-rv5j1201	1928	32	and	and	CC
cord-022561-rv5j1201	1928	33	macrophages	macrophage	NNS
cord-022561-rv5j1201	1928	34	)	)	-RRB-
cord-022561-rv5j1201	1928	35	to	to	TO
cord-022561-rv5j1201	1928	36	become	become	VB
cord-022561-rv5j1201	1928	37	visible	visible	JJ
cord-022561-rv5j1201	1928	38	.	.	.
cord-022561-rv5j1201	1929	1	With	with	IN
cord-022561-rv5j1201	1929	2	ongoing	ongoing	JJ
cord-022561-rv5j1201	1929	3	lymphocyte	lymphocyte	NN
cord-022561-rv5j1201	1929	4	depletion	depletion	NN
cord-022561-rv5j1201	1929	5	,	,	,
cord-022561-rv5j1201	1929	6	the	the	DT
cord-022561-rv5j1201	1929	7	mantle	mantle	NN
cord-022561-rv5j1201	1929	8	cell	cell	NN
cord-022561-rv5j1201	1929	9	zones	zone	NNS
cord-022561-rv5j1201	1929	10	are	be	VBP
cord-022561-rv5j1201	1929	11	thinned	thin	VBN
cord-022561-rv5j1201	1929	12	,	,	,
cord-022561-rv5j1201	1929	13	less	less	RBR
cord-022561-rv5j1201	1929	14	populated	populated	JJ
cord-022561-rv5j1201	1929	15	,	,	,
cord-022561-rv5j1201	1929	16	and	and	CC
cord-022561-rv5j1201	1929	17	discontinuous	discontinuous	JJ
cord-022561-rv5j1201	1929	18	.	.	.
cord-022561-rv5j1201	1930	1	Eventually	eventually	RB
cord-022561-rv5j1201	1930	2	,	,	,
cord-022561-rv5j1201	1930	3	residual	residual	JJ
cord-022561-rv5j1201	1930	4	mantle	mantle	NN
cord-022561-rv5j1201	1930	5	cells	cell	NNS
cord-022561-rv5j1201	1930	6	collapse	collapse	VBP
cord-022561-rv5j1201	1930	7	into	into	IN
cord-022561-rv5j1201	1930	8	the	the	DT
cord-022561-rv5j1201	1930	9	follicular	follicular	JJ
cord-022561-rv5j1201	1930	10	stroma	stroma	NN
cord-022561-rv5j1201	1930	11	,	,	,
cord-022561-rv5j1201	1930	12	forming	form	VBG
cord-022561-rv5j1201	1930	13	clusters	cluster	NNS
cord-022561-rv5j1201	1930	14	of	of	IN
cord-022561-rv5j1201	1930	15	small	small	JJ
cord-022561-rv5j1201	1930	16	dark	dark	JJ
cord-022561-rv5j1201	1930	17	cells	cell	NNS
cord-022561-rv5j1201	1930	18	within	within	IN
cord-022561-rv5j1201	1930	19	the	the	DT
cord-022561-rv5j1201	1930	20	bed	bed	NN
cord-022561-rv5j1201	1930	21	of	of	IN
cord-022561-rv5j1201	1930	22	DCs	DCs	NNP
cord-022561-rv5j1201	1930	23	and	and	CC
cord-022561-rv5j1201	1930	24	macrophages	macrophage	NNS
cord-022561-rv5j1201	1930	25	,	,	,
cord-022561-rv5j1201	1930	26	referred	refer	VBD
cord-022561-rv5j1201	1930	27	to	to	IN
cord-022561-rv5j1201	1930	28	as	as	IN
cord-022561-rv5j1201	1930	29	fading	fading	JJ
cord-022561-rv5j1201	1930	30	follicles	follicle	NNS
cord-022561-rv5j1201	1930	31	.	.	.
cord-022561-rv5j1201	1931	1	Paracortex	Paracortex	NNP
cord-022561-rv5j1201	1931	2	.	.	.
cord-022561-rv5j1201	1932	1	Paracortical	Paracortical	NNP
cord-022561-rv5j1201	1932	2	atrophy	atrophy	NN
cord-022561-rv5j1201	1932	3	may	may	MD
cord-022561-rv5j1201	1932	4	result	result	VB
cord-022561-rv5j1201	1932	5	from	from	IN
cord-022561-rv5j1201	1932	6	a	a	DT
cord-022561-rv5j1201	1932	7	variety	variety	NN
cord-022561-rv5j1201	1932	8	of	of	IN
cord-022561-rv5j1201	1932	9	causes	cause	NNS
cord-022561-rv5j1201	1932	10	,	,	,
cord-022561-rv5j1201	1932	11	including	include	VBG
cord-022561-rv5j1201	1932	12	deficiency	deficiency	NN
cord-022561-rv5j1201	1932	13	in	in	IN
cord-022561-rv5j1201	1932	14	lymphocyte	lymphocyte	NN
cord-022561-rv5j1201	1932	15	production	production	NN
cord-022561-rv5j1201	1932	16	in	in	IN
cord-022561-rv5j1201	1932	17	the	the	DT
cord-022561-rv5j1201	1932	18	bone	bone	NN
cord-022561-rv5j1201	1932	19	marrow	marrow	NN
cord-022561-rv5j1201	1932	20	,	,	,
cord-022561-rv5j1201	1932	21	reduced	reduce	VBN
cord-022561-rv5j1201	1932	22	differential	differential	NN
cord-022561-rv5j1201	1932	23	selection	selection	NN
cord-022561-rv5j1201	1932	24	of	of	IN
cord-022561-rv5j1201	1932	25	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	1932	26	in	in	IN
cord-022561-rv5j1201	1932	27	the	the	DT
cord-022561-rv5j1201	1932	28	thymus	thymus	NN
cord-022561-rv5j1201	1932	29	,	,	,
cord-022561-rv5j1201	1932	30	or	or	CC
cord-022561-rv5j1201	1932	31	destruction	destruction	NN
cord-022561-rv5j1201	1932	32	of	of	IN
cord-022561-rv5j1201	1932	33	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	1932	34	in	in	IN
cord-022561-rv5j1201	1932	35	the	the	DT
cord-022561-rv5j1201	1932	36	lymph	lymph	NN
cord-022561-rv5j1201	1932	37	node	node	NN
cord-022561-rv5j1201	1932	38	by	by	IN
cord-022561-rv5j1201	1932	39	viruses	virus	NNS
cord-022561-rv5j1201	1932	40	,	,	,
cord-022561-rv5j1201	1932	41	radiation	radiation	NN
cord-022561-rv5j1201	1932	42	,	,	,
cord-022561-rv5j1201	1932	43	and	and	CC
cord-022561-rv5j1201	1932	44	toxins	toxin	NNS
cord-022561-rv5j1201	1932	45	directly	directly	RB
cord-022561-rv5j1201	1932	46	on	on	IN
cord-022561-rv5j1201	1932	47	the	the	DT
cord-022561-rv5j1201	1932	48	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	1932	49	in	in	IN
cord-022561-rv5j1201	1932	50	the	the	DT
cord-022561-rv5j1201	1932	51	lymph	lymph	NN
cord-022561-rv5j1201	1932	52	node	node	NN
cord-022561-rv5j1201	1932	53	(	(	-LRB-
cord-022561-rv5j1201	1932	54	see	see	VB
cord-022561-rv5j1201	1932	55	Box	Box	NNP
cord-022561-rv5j1201	1932	56	13	13	CD
cord-022561-rv5j1201	1932	57	-	-	SYM
cord-022561-rv5j1201	1932	58	5	5	CD
cord-022561-rv5j1201	1932	59	)	)	-RRB-
cord-022561-rv5j1201	1932	60	.	.	.
cord-022561-rv5j1201	1933	1	Examination	examination	NN
cord-022561-rv5j1201	1933	2	of	of	IN
cord-022561-rv5j1201	1933	3	H&E	H&E	NNP
cord-022561-rv5j1201	1933	4	-	-	HYPH
cord-022561-rv5j1201	1933	5	stained	stain	VBN
cord-022561-rv5j1201	1933	6	sections	section	NNS
cord-022561-rv5j1201	1933	7	allows	allow	VBZ
cord-022561-rv5j1201	1933	8	evaluation	evaluation	NN
cord-022561-rv5j1201	1933	9	of	of	IN
cord-022561-rv5j1201	1933	10	follicular	follicular	JJ
cord-022561-rv5j1201	1933	11	activity	activity	NN
cord-022561-rv5j1201	1933	12	in	in	IN
cord-022561-rv5j1201	1933	13	the	the	DT
cord-022561-rv5j1201	1933	14	cortex	cortex	NN
cord-022561-rv5j1201	1933	15	and	and	CC
cord-022561-rv5j1201	1933	16	the	the	DT
cord-022561-rv5j1201	1933	17	concentration	concentration	NN
cord-022561-rv5j1201	1933	18	of	of	IN
cord-022561-rv5j1201	1933	19	plasma	plasma	NN
cord-022561-rv5j1201	1933	20	cells	cell	NNS
cord-022561-rv5j1201	1933	21	in	in	IN
cord-022561-rv5j1201	1933	22	the	the	DT
cord-022561-rv5j1201	1933	23	medullary	medullary	JJ
cord-022561-rv5j1201	1933	24	cords	cord	NNS
cord-022561-rv5j1201	1933	25	,	,	,
cord-022561-rv5j1201	1933	26	which	which	WDT
cord-022561-rv5j1201	1933	27	serve	serve	VBP
cord-022561-rv5j1201	1933	28	as	as	IN
cord-022561-rv5j1201	1933	29	a	a	DT
cord-022561-rv5j1201	1933	30	reasonable	reasonable	JJ
cord-022561-rv5j1201	1933	31	estimate	estimate	NN
cord-022561-rv5j1201	1933	32	of	of	IN
cord-022561-rv5j1201	1933	33	B	b	NN
cord-022561-rv5j1201	1933	34	lymphocyte	lymphocyte	NN
cord-022561-rv5j1201	1933	35	activity	activity	NN
cord-022561-rv5j1201	1933	36	for	for	IN
cord-022561-rv5j1201	1933	37	comparison	comparison	NN
cord-022561-rv5j1201	1933	38	.	.	.
cord-022561-rv5j1201	1934	1	Paracortical	Paracortical	NNP
cord-022561-rv5j1201	1934	2	hyperplasia	hyperplasia	NN
cord-022561-rv5j1201	1934	3	may	may	MD
cord-022561-rv5j1201	1934	4	have	have	VB
cord-022561-rv5j1201	1934	5	a	a	DT
cord-022561-rv5j1201	1934	6	nodular	nodular	JJ
cord-022561-rv5j1201	1934	7	or	or	CC
cord-022561-rv5j1201	1934	8	diffuse	diffuse	JJ
cord-022561-rv5j1201	1934	9	appearance	appearance	NN
cord-022561-rv5j1201	1934	10	depending	depend	VBG
cord-022561-rv5j1201	1934	11	on	on	IN
cord-022561-rv5j1201	1934	12	which	which	WDT
cord-022561-rv5j1201	1934	13	and	and	CC
cord-022561-rv5j1201	1934	14	how	how	WRB
cord-022561-rv5j1201	1934	15	many	many	JJ
cord-022561-rv5j1201	1934	16	afferent	afferent	JJ
cord-022561-rv5j1201	1934	17	lymphatic	lymphatic	NN
cord-022561-rv5j1201	1934	18	vessels	vessel	NNS
cord-022561-rv5j1201	1934	19	are	be	VBP
cord-022561-rv5j1201	1934	20	draining	drain	VBG
cord-022561-rv5j1201	1934	21	antigen	antigen	NN
cord-022561-rv5j1201	1934	22	.	.	.
cord-022561-rv5j1201	1935	1	This	this	DT
cord-022561-rv5j1201	1935	2	reaction	reaction	NN
cord-022561-rv5j1201	1935	3	may	may	MD
cord-022561-rv5j1201	1935	4	precede	precede	VB
cord-022561-rv5j1201	1935	5	or	or	CC
cord-022561-rv5j1201	1935	6	be	be	VB
cord-022561-rv5j1201	1935	7	concurrent	concurrent	JJ
cord-022561-rv5j1201	1935	8	with	with	IN
cord-022561-rv5j1201	1935	9	the	the	DT
cord-022561-rv5j1201	1935	10	germinal	germinal	JJ
cord-022561-rv5j1201	1935	11	center	center	NN
cord-022561-rv5j1201	1935	12	reaction	reaction	NN
cord-022561-rv5j1201	1935	13	of	of	IN
cord-022561-rv5j1201	1935	14	follicular	follicular	JJ
cord-022561-rv5j1201	1935	15	hyperplasia	hyperplasia	NN
cord-022561-rv5j1201	1935	16	.	.	.
cord-022561-rv5j1201	1936	1	Proliferation	proliferation	NN
cord-022561-rv5j1201	1936	2	of	of	IN
cord-022561-rv5j1201	1936	3	T	t	NN
cord-022561-rv5j1201	1936	4	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	1936	5	has	have	VBZ
cord-022561-rv5j1201	1936	6	been	be	VBN
cord-022561-rv5j1201	1936	7	reported	report	VBN
cord-022561-rv5j1201	1936	8	in	in	IN
cord-022561-rv5j1201	1936	9	the	the	DT
cord-022561-rv5j1201	1936	10	paracortex	paracortex	NN
cord-022561-rv5j1201	1936	11	(	(	-LRB-
cord-022561-rv5j1201	1936	12	and	and	CC
cord-022561-rv5j1201	1936	13	PALS	pals	NN
cord-022561-rv5j1201	1936	14	of	of	IN
cord-022561-rv5j1201	1936	15	the	the	DT
cord-022561-rv5j1201	1936	16	spleen	spleen	NN
cord-022561-rv5j1201	1936	17	)	)	-RRB-
cord-022561-rv5j1201	1936	18	in	in	IN
cord-022561-rv5j1201	1936	19	malignant	malignant	JJ
cord-022561-rv5j1201	1936	20	catarrhal	catarrhal	NN
cord-022561-rv5j1201	1936	21	fever	fever	NN
cord-022561-rv5j1201	1936	22	(	(	-LRB-
cord-022561-rv5j1201	1936	23	MCF	MCF	NNP
cord-022561-rv5j1201	1936	24	)	)	-RRB-
cord-022561-rv5j1201	1936	25	in	in	IN
cord-022561-rv5j1201	1936	26	cattle	cattle	NNS
cord-022561-rv5j1201	1936	27	and	and	CC
cord-022561-rv5j1201	1936	28	in	in	IN
cord-022561-rv5j1201	1936	29	pigs	pig	NNS
cord-022561-rv5j1201	1936	30	with	with	IN
cord-022561-rv5j1201	1936	31	porcine	porcine	JJ
cord-022561-rv5j1201	1936	32	reproductive	reproductive	JJ
cord-022561-rv5j1201	1936	33	and	and	CC
cord-022561-rv5j1201	1936	34	respiratory	respiratory	JJ
cord-022561-rv5j1201	1936	35	syndrome	syndrome	NN
cord-022561-rv5j1201	1936	36	.	.	.
cord-022561-rv5j1201	1937	1	PCV2	PCV2	NNP
cord-022561-rv5j1201	1937	2	can	can	MD
cord-022561-rv5j1201	1937	3	cause	cause	VB
cord-022561-rv5j1201	1937	4	a	a	DT
cord-022561-rv5j1201	1937	5	diffuse	diffuse	JJ
cord-022561-rv5j1201	1937	6	proliferation	proliferation	NN
cord-022561-rv5j1201	1937	7	of	of	IN
cord-022561-rv5j1201	1937	8	macrophages	macrophage	NNS
cord-022561-rv5j1201	1937	9	within	within	IN
cord-022561-rv5j1201	1937	10	the	the	DT
cord-022561-rv5j1201	1937	11	paracortex	paracortex	NNP
cord-022561-rv5j1201	1937	12	.	.	.
cord-022561-rv5j1201	1938	1	Responses	response	NNS
cord-022561-rv5j1201	1938	2	to	to	IN
cord-022561-rv5j1201	1938	3	injury	injury	NN
cord-022561-rv5j1201	1938	4	by	by	IN
cord-022561-rv5j1201	1938	5	the	the	DT
cord-022561-rv5j1201	1938	6	medullary	medullary	JJ
cord-022561-rv5j1201	1938	7	sinuses	sinus	NNS
cord-022561-rv5j1201	1938	8	are	be	VBP
cord-022561-rv5j1201	1938	9	dilation	dilation	NN
cord-022561-rv5j1201	1938	10	of	of	IN
cord-022561-rv5j1201	1938	11	the	the	DT
cord-022561-rv5j1201	1938	12	sinuses	sinus	NNS
cord-022561-rv5j1201	1938	13	and	and	CC
cord-022561-rv5j1201	1938	14	proliferation	proliferation	NN
cord-022561-rv5j1201	1938	15	of	of	IN
cord-022561-rv5j1201	1938	16	histiocytes	histiocyte	NNS
cord-022561-rv5j1201	1938	17	(	(	-LRB-
cord-022561-rv5j1201	1938	18	"	"	``
cord-022561-rv5j1201	1938	19	sinus	sinus	NNP
cord-022561-rv5j1201	1938	20	histiocytosis	histiocytosis	NN
cord-022561-rv5j1201	1938	21	"	"	''
cord-022561-rv5j1201	1938	22	)	)	-RRB-
cord-022561-rv5j1201	1938	23	.	.	.
cord-022561-rv5j1201	1939	1	Sinus	sinus	NN
cord-022561-rv5j1201	1939	2	macrophages	macrophage	NNS
cord-022561-rv5j1201	1939	3	proliferate	proliferate	VBP
cord-022561-rv5j1201	1939	4	in	in	IN
cord-022561-rv5j1201	1939	5	response	response	NN
cord-022561-rv5j1201	1939	6	to	to	IN
cord-022561-rv5j1201	1939	7	a	a	DT
cord-022561-rv5j1201	1939	8	wide	wide	JJ
cord-022561-rv5j1201	1939	9	variety	variety	NN
cord-022561-rv5j1201	1939	10	of	of	IN
cord-022561-rv5j1201	1939	11	particulate	particulate	NN
cord-022561-rv5j1201	1939	12	matter	matter	NN
cord-022561-rv5j1201	1939	13	in	in	IN
cord-022561-rv5j1201	1939	14	the	the	DT
cord-022561-rv5j1201	1939	15	lymph	lymph	NN
cord-022561-rv5j1201	1939	16	,	,	,
cord-022561-rv5j1201	1939	17	including	include	VBG
cord-022561-rv5j1201	1939	18	bacteria	bacteria	NNS
cord-022561-rv5j1201	1939	19	and	and	CC
cord-022561-rv5j1201	1939	20	erythrocytes	erythrocyte	NNS
cord-022561-rv5j1201	1939	21	(	(	-LRB-
cord-022561-rv5j1201	1939	22	erythrophagocytosis	erythrophagocytosis	NNP
cord-022561-rv5j1201	1939	23	)	)	-RRB-
cord-022561-rv5j1201	1939	24	draining	drain	VBG
cord-022561-rv5j1201	1939	25	from	from	IN
cord-022561-rv5j1201	1939	26	a	a	DT
cord-022561-rv5j1201	1939	27	hemorrhagic	hemorrhagic	JJ
cord-022561-rv5j1201	1939	28	area	area	NN
cord-022561-rv5j1201	1939	29	(	(	-LRB-
cord-022561-rv5j1201	1939	30	see	see	VB
cord-022561-rv5j1201	1939	31	Lymphoid	Lymphoid	NNP
cord-022561-rv5j1201	1939	32	/	/	SYM
cord-022561-rv5j1201	1939	33	Lymphatic	Lymphatic	NNP
cord-022561-rv5j1201	1939	34	System	System	NNP
cord-022561-rv5j1201	1939	35	,	,	,
cord-022561-rv5j1201	1939	36	Disorders	disorder	NNS
cord-022561-rv5j1201	1939	37	of	of	IN
cord-022561-rv5j1201	1939	38	Domestic	domestic	JJ
cord-022561-rv5j1201	1939	39	Animals	animal	NNS
cord-022561-rv5j1201	1939	40	:	:	:
cord-022561-rv5j1201	1939	41	Lymph	lymph	NN
cord-022561-rv5j1201	1939	42	Nodes	node	NNS
cord-022561-rv5j1201	1939	43	,	,	,
cord-022561-rv5j1201	1939	44	Pigmentation	pigmentation	NN
cord-022561-rv5j1201	1939	45	of	of	IN
cord-022561-rv5j1201	1939	46	Lymph	lymph	NN
cord-022561-rv5j1201	1939	47	Nodes	node	NNS
cord-022561-rv5j1201	1939	48	)	)	-RRB-
cord-022561-rv5j1201	1939	49	.	.	.
cord-022561-rv5j1201	1940	1	Dilation	dilation	NN
cord-022561-rv5j1201	1940	2	of	of	IN
cord-022561-rv5j1201	1940	3	the	the	DT
cord-022561-rv5j1201	1940	4	sinuses	sinus	NNS
cord-022561-rv5j1201	1940	5	due	due	IN
cord-022561-rv5j1201	1940	6	to	to	IN
cord-022561-rv5j1201	1940	7	edema	edema	NN
cord-022561-rv5j1201	1940	8	occurs	occur	VBZ
cord-022561-rv5j1201	1940	9	with	with	IN
cord-022561-rv5j1201	1940	10	many	many	JJ
cord-022561-rv5j1201	1940	11	underlying	underlying	JJ
cord-022561-rv5j1201	1940	12	conditions	condition	NNS
cord-022561-rv5j1201	1940	13	,	,	,
cord-022561-rv5j1201	1940	14	including	include	VBG
cord-022561-rv5j1201	1940	15	chronic	chronic	JJ
cord-022561-rv5j1201	1940	16	cardiac	cardiac	JJ
cord-022561-rv5j1201	1940	17	failure	failure	NN
cord-022561-rv5j1201	1940	18	or	or	CC
cord-022561-rv5j1201	1940	19	drainage	drainage	NN
cord-022561-rv5j1201	1940	20	from	from	IN
cord-022561-rv5j1201	1940	21	an	an	DT
cord-022561-rv5j1201	1940	22	acutely	acutely	RB
cord-022561-rv5j1201	1940	23	inflamed	inflamed	JJ
cord-022561-rv5j1201	1940	24	area	area	NN
cord-022561-rv5j1201	1940	25	.	.	.
cord-022561-rv5j1201	1941	1	As	as	IN
cord-022561-rv5j1201	1941	2	the	the	DT
cord-022561-rv5j1201	1941	3	inflammation	inflammation	NN
cord-022561-rv5j1201	1941	4	progresses	progress	VBZ
cord-022561-rv5j1201	1941	5	,	,	,
cord-022561-rv5j1201	1941	6	the	the	DT
cord-022561-rv5j1201	1941	7	sinuses	sinus	NNS
cord-022561-rv5j1201	1941	8	become	become	VBP
cord-022561-rv5j1201	1941	9	filled	fill	VBN
cord-022561-rv5j1201	1941	10	with	with	IN
cord-022561-rv5j1201	1941	11	neutrophils	neutrophil	NNS
cord-022561-rv5j1201	1941	12	,	,	,
cord-022561-rv5j1201	1941	13	macrophages	macrophage	NNS
cord-022561-rv5j1201	1941	14	,	,	,
cord-022561-rv5j1201	1941	15	and	and	CC
cord-022561-rv5j1201	1941	16	occasionally	occasionally	RB
cord-022561-rv5j1201	1941	17	fibrin	fibrin	NN
cord-022561-rv5j1201	1941	18	,	,	,
cord-022561-rv5j1201	1941	19	in	in	IN
cord-022561-rv5j1201	1941	20	addition	addition	NN
cord-022561-rv5j1201	1941	21	to	to	IN
cord-022561-rv5j1201	1941	22	the	the	DT
cord-022561-rv5j1201	1941	23	hyperplastic	hyperplastic	JJ
cord-022561-rv5j1201	1941	24	resident	resident	JJ
cord-022561-rv5j1201	1941	25	sinus	sinus	NNP
cord-022561-rv5j1201	1941	26	histiocytes	histiocytes	NNPS
cord-022561-rv5j1201	1941	27	(	(	-LRB-
cord-022561-rv5j1201	1941	28	see	see	VB
cord-022561-rv5j1201	1941	29	Fig	Fig	NNP
cord-022561-rv5j1201	1941	30	.	.	.
cord-022561-rv5j1201	1942	1	13	13	CD
cord-022561-rv5j1201	1942	2	-	-	SYM
cord-022561-rv5j1201	1942	3	48	48	CD
cord-022561-rv5j1201	1942	4	)	)	-RRB-
cord-022561-rv5j1201	1942	5	.	.	.
cord-022561-rv5j1201	1943	1	Depending	depend	VBG
cord-022561-rv5j1201	1943	2	on	on	IN
cord-022561-rv5j1201	1943	3	the	the	DT
cord-022561-rv5j1201	1943	4	intensity	intensity	NN
cord-022561-rv5j1201	1943	5	of	of	IN
cord-022561-rv5j1201	1943	6	the	the	DT
cord-022561-rv5j1201	1943	7	inflammation	inflammation	NN
cord-022561-rv5j1201	1943	8	,	,	,
cord-022561-rv5j1201	1943	9	the	the	DT
cord-022561-rv5j1201	1943	10	adjacent	adjacent	JJ
cord-022561-rv5j1201	1943	11	parenchyma	parenchyma	NN
cord-022561-rv5j1201	1943	12	may	may	MD
cord-022561-rv5j1201	1943	13	become	become	VB
cord-022561-rv5j1201	1943	14	affected	affected	JJ
cord-022561-rv5j1201	1943	15	(	(	-LRB-
cord-022561-rv5j1201	1943	16	see	see	VB
cord-022561-rv5j1201	1943	17	Lymphoid	Lymphoid	NNP
cord-022561-rv5j1201	1943	18	/	/	SYM
cord-022561-rv5j1201	1943	19	Lymphatic	Lymphatic	NNP
cord-022561-rv5j1201	1943	20	System	System	NNP
cord-022561-rv5j1201	1943	21	,	,	,
cord-022561-rv5j1201	1943	22	Disorders	disorder	NNS
cord-022561-rv5j1201	1943	23	of	of	IN
cord-022561-rv5j1201	1943	24	Domestic	domestic	JJ
cord-022561-rv5j1201	1943	25	Animals	animal	NNS
cord-022561-rv5j1201	1943	26	:	:	:
cord-022561-rv5j1201	1943	27	Lymph	lymph	NN
cord-022561-rv5j1201	1943	28	Nodes	node	NNS
cord-022561-rv5j1201	1943	29	,	,	,
cord-022561-rv5j1201	1943	30	Enlarged	enlarged	JJ
cord-022561-rv5j1201	1943	31	Lymph	lymph	NN
cord-022561-rv5j1201	1943	32	Nodes	node	NNS
cord-022561-rv5j1201	1943	33	[	[	-LRB-
cord-022561-rv5j1201	1943	34	Lymphadenomegaly	Lymphadenomegaly	NNP
cord-022561-rv5j1201	1943	35	]	]	-RRB-
cord-022561-rv5j1201	1943	36	,	,	,
cord-022561-rv5j1201	1943	37	Acute	Acute	NNP
cord-022561-rv5j1201	1943	38	Lymphadenitis	Lymphadenitis	NNP
cord-022561-rv5j1201	1943	39	)	)	-RRB-
cord-022561-rv5j1201	1943	40	.	.	.
cord-022561-rv5j1201	1944	1	As	as	IN
cord-022561-rv5j1201	1944	2	pointed	point	VBN
cord-022561-rv5j1201	1944	3	out	out	RP
cord-022561-rv5j1201	1944	4	in	in	IN
cord-022561-rv5j1201	1944	5	the	the	DT
cord-022561-rv5j1201	1944	6	section	section	NN
cord-022561-rv5j1201	1944	7	on	on	IN
cord-022561-rv5j1201	1944	8	Lymph	Lymph	NNP
cord-022561-rv5j1201	1944	9	Nodes	node	NNS
cord-022561-rv5j1201	1944	10	,	,	,
cord-022561-rv5j1201	1944	11	Function	function	NN
cord-022561-rv5j1201	1944	12	,	,	,
cord-022561-rv5j1201	1944	13	after	after	IN
cord-022561-rv5j1201	1944	14	activation	activation	NN
cord-022561-rv5j1201	1944	15	and	and	CC
cord-022561-rv5j1201	1944	16	proliferation	proliferation	NN
cord-022561-rv5j1201	1944	17	of	of	IN
cord-022561-rv5j1201	1944	18	B	b	NN
cord-022561-rv5j1201	1944	19	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	1944	20	in	in	IN
cord-022561-rv5j1201	1944	21	the	the	DT
cord-022561-rv5j1201	1944	22	follicle	follicle	NN
cord-022561-rv5j1201	1944	23	,	,	,
cord-022561-rv5j1201	1944	24	the	the	DT
cord-022561-rv5j1201	1944	25	immunoblasts	immunoblast	NNS
cord-022561-rv5j1201	1944	26	formed	form	VBD
cord-022561-rv5j1201	1944	27	there	there	RB
cord-022561-rv5j1201	1944	28	move	move	VB
cord-022561-rv5j1201	1944	29	to	to	IN
cord-022561-rv5j1201	1944	30	and	and	CC
cord-022561-rv5j1201	1944	31	mature	mature	VB
cord-022561-rv5j1201	1944	32	in	in	IN
cord-022561-rv5j1201	1944	33	the	the	DT
cord-022561-rv5j1201	1944	34	medullary	medullary	JJ
cord-022561-rv5j1201	1944	35	cords	cord	NNS
cord-022561-rv5j1201	1944	36	,	,	,
cord-022561-rv5j1201	1944	37	which	which	WDT
cord-022561-rv5j1201	1944	38	as	as	IN
cord-022561-rv5j1201	1944	39	a	a	DT
cord-022561-rv5j1201	1944	40	result	result	NN
cord-022561-rv5j1201	1944	41	are	be	VBP
cord-022561-rv5j1201	1944	42	distended	distend	VBN
cord-022561-rv5j1201	1944	43	with	with	IN
cord-022561-rv5j1201	1944	44	plasma	plasma	NN
cord-022561-rv5j1201	1944	45	cells	cell	NNS
cord-022561-rv5j1201	1944	46	that	that	WDT
cord-022561-rv5j1201	1944	47	secrete	secrete	VBP
cord-022561-rv5j1201	1944	48	antibody	antibody	NN
cord-022561-rv5j1201	1944	49	into	into	IN
cord-022561-rv5j1201	1944	50	the	the	DT
cord-022561-rv5j1201	1944	51	efferent	efferent	JJ
cord-022561-rv5j1201	1944	52	lymphatic	lymphatic	JJ
cord-022561-rv5j1201	1944	53	vessels	vessel	NNS
cord-022561-rv5j1201	1944	54	(	(	-LRB-
cord-022561-rv5j1201	1944	55	"	"	``
cord-022561-rv5j1201	1944	56	medullary	medullary	JJ
cord-022561-rv5j1201	1944	57	plasmacytosis	plasmacytosis	NN
cord-022561-rv5j1201	1944	58	"	"	''
cord-022561-rv5j1201	1944	59	)	)	-RRB-
cord-022561-rv5j1201	1944	60	.	.	.
cord-022561-rv5j1201	1945	1	The	the	DT
cord-022561-rv5j1201	1945	2	concentration	concentration	NN
cord-022561-rv5j1201	1945	3	of	of	IN
cord-022561-rv5j1201	1945	4	medullary	medullary	JJ
cord-022561-rv5j1201	1945	5	plasma	plasma	NN
cord-022561-rv5j1201	1945	6	cells	cell	NNS
cord-022561-rv5j1201	1945	7	correlates	correlate	VBZ
cord-022561-rv5j1201	1945	8	with	with	IN
cord-022561-rv5j1201	1945	9	the	the	DT
cord-022561-rv5j1201	1945	10	activity	activity	NN
cord-022561-rv5j1201	1945	11	of	of	IN
cord-022561-rv5j1201	1945	12	the	the	DT
cord-022561-rv5j1201	1945	13	germinal	germinal	JJ
cord-022561-rv5j1201	1945	14	centers	center	NNS
cord-022561-rv5j1201	1945	15	.	.	.
cord-022561-rv5j1201	1946	1	As	as	IN
cord-022561-rv5j1201	1946	2	the	the	DT
cord-022561-rv5j1201	1946	3	immune	immune	JJ
cord-022561-rv5j1201	1946	4	response	response	NN
cord-022561-rv5j1201	1946	5	subsides	subside	VBZ
cord-022561-rv5j1201	1946	6	,	,	,
cord-022561-rv5j1201	1946	7	the	the	DT
cord-022561-rv5j1201	1946	8	number	number	NN
cord-022561-rv5j1201	1946	9	of	of	IN
cord-022561-rv5j1201	1946	10	plasma	plasma	NN
cord-022561-rv5j1201	1946	11	cells	cell	NNS
cord-022561-rv5j1201	1946	12	decreases	decrease	VBZ
cord-022561-rv5j1201	1946	13	and	and	CC
cord-022561-rv5j1201	1946	14	the	the	DT
cord-022561-rv5j1201	1946	15	medullary	medullary	JJ
cord-022561-rv5j1201	1946	16	cords	cord	NNS
cord-022561-rv5j1201	1946	17	return	return	VB
cord-022561-rv5j1201	1946	18	to	to	IN
cord-022561-rv5j1201	1946	19	their	-PRON-	PRP$
cord-022561-rv5j1201	1946	20	resting	rest	VBG
cord-022561-rv5j1201	1946	21	state	state	NN
cord-022561-rv5j1201	1946	22	populated	populate	VBN
cord-022561-rv5j1201	1946	23	by	by	IN
cord-022561-rv5j1201	1946	24	few	few	JJ
cord-022561-rv5j1201	1946	25	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	1946	26	and	and	CC
cord-022561-rv5j1201	1946	27	scattered	scatter	VBN
cord-022561-rv5j1201	1946	28	plasma	plasma	NN
cord-022561-rv5j1201	1946	29	cells	cell	NNS
cord-022561-rv5j1201	1946	30	.	.	.
cord-022561-rv5j1201	1947	1	CHAPTER	chapter	NN
cord-022561-rv5j1201	1947	2	13	13	CD
cord-022561-rv5j1201	1947	3	Bone	Bone	NNP
cord-022561-rv5j1201	1947	4	Marrow	Marrow	NNP
cord-022561-rv5j1201	1947	5	,	,	,
cord-022561-rv5j1201	1947	6	Blood	blood	NN
cord-022561-rv5j1201	1947	7	Cells	cell	NNS
cord-022561-rv5j1201	1947	8	,	,	,
cord-022561-rv5j1201	1947	9	and	and	CC
cord-022561-rv5j1201	1947	10	the	the	DT
cord-022561-rv5j1201	1947	11	Lymphoid	Lymphoid	NNP
cord-022561-rv5j1201	1947	12	/	/	SYM
cord-022561-rv5j1201	1947	13	Lymphatic	Lymphatic	NNP
cord-022561-rv5j1201	1947	14	System	System	NNP
cord-022561-rv5j1201	1947	15	composition	composition	NN
cord-022561-rv5j1201	1947	16	.	.	.
cord-022561-rv5j1201	1948	1	For	for	IN
cord-022561-rv5j1201	1948	2	instance	instance	NN
cord-022561-rv5j1201	1948	3	,	,	,
cord-022561-rv5j1201	1948	4	M	M	NNP
cord-022561-rv5j1201	1948	5	cells	cell	NNS
cord-022561-rv5j1201	1948	6	increase	increase	VBP
cord-022561-rv5j1201	1948	7	in	in	IN
cord-022561-rv5j1201	1948	8	animals	animal	NNS
cord-022561-rv5j1201	1948	9	transferred	transfer	VBN
cord-022561-rv5j1201	1948	10	from	from	IN
cord-022561-rv5j1201	1948	11	pathogen	pathogen	NN
cord-022561-rv5j1201	1948	12	-	-	HYPH
cord-022561-rv5j1201	1948	13	free	free	JJ
cord-022561-rv5j1201	1948	14	housing	housing	NN
cord-022561-rv5j1201	1948	15	to	to	IN
cord-022561-rv5j1201	1948	16	the	the	DT
cord-022561-rv5j1201	1948	17	normal	normal	JJ
cord-022561-rv5j1201	1948	18	environment	environment	NN
cord-022561-rv5j1201	1948	19	.	.	.
cord-022561-rv5j1201	1949	1	M	M	NNP
cord-022561-rv5j1201	1949	2	cells	cell	NNS
cord-022561-rv5j1201	1949	3	may	may	MD
cord-022561-rv5j1201	1949	4	also	also	RB
cord-022561-rv5j1201	1949	5	be	be	VB
cord-022561-rv5j1201	1949	6	exploited	exploit	VBN
cord-022561-rv5j1201	1949	7	as	as	IN
cord-022561-rv5j1201	1949	8	a	a	DT
cord-022561-rv5j1201	1949	9	portal	portal	NN
cord-022561-rv5j1201	1949	10	for	for	IN
cord-022561-rv5j1201	1949	11	entry	entry	NN
cord-022561-rv5j1201	1949	12	by	by	IN
cord-022561-rv5j1201	1949	13	some	some	DT
cord-022561-rv5j1201	1949	14	microbes	microbe	NNS
cord-022561-rv5j1201	1949	15	(	(	-LRB-
cord-022561-rv5j1201	1949	16	see	see	VB
cord-022561-rv5j1201	1949	17	Lymphoid	Lymphoid	NNP
cord-022561-rv5j1201	1949	18	/	/	SYM
cord-022561-rv5j1201	1949	19	Lymphatic	Lymphatic	NNP
cord-022561-rv5j1201	1949	20	System	System	NNP
cord-022561-rv5j1201	1949	21	,	,	,
cord-022561-rv5j1201	1949	22	Portals	Portals	NNPS
cord-022561-rv5j1201	1949	23	of	of	IN
cord-022561-rv5j1201	1949	24	Entry	Entry	NNP
cord-022561-rv5j1201	1949	25	/	/	SYM
cord-022561-rv5j1201	1949	26	Pathways	Pathways	NNPS
cord-022561-rv5j1201	1949	27	of	of	IN
cord-022561-rv5j1201	1949	28	Spread	Spread	NNP
cord-022561-rv5j1201	1949	29	)	)	-RRB-
cord-022561-rv5j1201	1949	30	.	.	.
cord-022561-rv5j1201	1950	1	Table	table	NN
cord-022561-rv5j1201	1950	2	13	13	CD
cord-022561-rv5j1201	1950	3	-5	-5	NNP
cord-022561-rv5j1201	1950	4	lists	list	VBZ
cord-022561-rv5j1201	1950	5	the	the	DT
cord-022561-rv5j1201	1950	6	interactions	interaction	NNS
cord-022561-rv5j1201	1950	7	of	of	IN
cord-022561-rv5j1201	1950	8	the	the	DT
cord-022561-rv5j1201	1950	9	MALT	malt	NN
cord-022561-rv5j1201	1950	10	with	with	IN
cord-022561-rv5j1201	1950	11	different	different	JJ
cord-022561-rv5j1201	1950	12	microorganisms	microorganism	NNS
cord-022561-rv5j1201	1950	13	.	.	.
cord-022561-rv5j1201	1951	1	The	the	DT
cord-022561-rv5j1201	1951	2	responses	response	NNS
cord-022561-rv5j1201	1951	3	of	of	IN
cord-022561-rv5j1201	1951	4	MALT	malt	NN
cord-022561-rv5j1201	1951	5	to	to	IN
cord-022561-rv5j1201	1951	6	injury	injury	NN
cord-022561-rv5j1201	1951	7	are	be	VBP
cord-022561-rv5j1201	1951	8	similar	similar	JJ
cord-022561-rv5j1201	1951	9	to	to	IN
cord-022561-rv5j1201	1951	10	those	those	DT
cord-022561-rv5j1201	1951	11	of	of	IN
cord-022561-rv5j1201	1951	12	other	other	JJ
cord-022561-rv5j1201	1951	13	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	1951	14	tissues	tissue	NNS
cord-022561-rv5j1201	1951	15	:	:	:
cord-022561-rv5j1201	1951	16	hyperplasia	hyperplasia	NN
cord-022561-rv5j1201	1951	17	,	,	,
cord-022561-rv5j1201	1951	18	atrophy	atrophy	NN
cord-022561-rv5j1201	1951	19	,	,	,
cord-022561-rv5j1201	1951	20	and	and	CC
cord-022561-rv5j1201	1951	21	inflammation	inflammation	NN
cord-022561-rv5j1201	1951	22	(	(	-LRB-
cord-022561-rv5j1201	1951	23	Box	Box	NNP
cord-022561-rv5j1201	1951	24	13	13	CD
cord-022561-rv5j1201	1951	25	-	-	SYM
cord-022561-rv5j1201	1951	26	10	10	CD
cord-022561-rv5j1201	1951	27	)	)	-RRB-
cord-022561-rv5j1201	1951	28	.	.	.
cord-022561-rv5j1201	1952	1	Hyperplasia	hyperplasia	NN
cord-022561-rv5j1201	1952	2	.	.	.
cord-022561-rv5j1201	1953	1	Hyperplasia	hyperplasia	NN
cord-022561-rv5j1201	1953	2	of	of	IN
cord-022561-rv5j1201	1953	3	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	1953	4	nodules	nodule	NNS
cord-022561-rv5j1201	1953	5	is	be	VBZ
cord-022561-rv5j1201	1953	6	a	a	DT
cord-022561-rv5j1201	1953	7	response	response	NN
cord-022561-rv5j1201	1953	8	to	to	IN
cord-022561-rv5j1201	1953	9	antigenic	antigenic	JJ
cord-022561-rv5j1201	1953	10	stimulation	stimulation	NN
cord-022561-rv5j1201	1953	11	and	and	CC
cord-022561-rv5j1201	1953	12	consists	consist	VBZ
cord-022561-rv5j1201	1953	13	of	of	IN
cord-022561-rv5j1201	1953	14	activation	activation	NN
cord-022561-rv5j1201	1953	15	of	of	IN
cord-022561-rv5j1201	1953	16	germinal	germinal	JJ
cord-022561-rv5j1201	1953	17	centers	center	NNS
cord-022561-rv5j1201	1953	18	with	with	IN
cord-022561-rv5j1201	1953	19	subsequent	subsequent	JJ
cord-022561-rv5j1201	1953	20	production	production	NN
cord-022561-rv5j1201	1953	21	of	of	IN
cord-022561-rv5j1201	1953	22	plasma	plasma	NN
cord-022561-rv5j1201	1953	23	cells	cell	NNS
cord-022561-rv5j1201	1953	24	(	(	-LRB-
cord-022561-rv5j1201	1953	25	see	see	VB
cord-022561-rv5j1201	1953	26	Fig	Fig	NNP
cord-022561-rv5j1201	1953	27	.	.	.
cord-022561-rv5j1201	1954	1	13	13	CD
cord-022561-rv5j1201	1954	2	-	-	SYM
cord-022561-rv5j1201	1954	3	51	51	CD
cord-022561-rv5j1201	1954	4	,	,	,
cord-022561-rv5j1201	1954	5	B	B	NNP
cord-022561-rv5j1201	1954	6	)	)	-RRB-
cord-022561-rv5j1201	1954	7	.	.	.
cord-022561-rv5j1201	1955	1	Lymphoid	lymphoid	JJ
cord-022561-rv5j1201	1955	2	nodule	nodule	NN
cord-022561-rv5j1201	1955	3	hyperplasia	hyperplasia	NN
cord-022561-rv5j1201	1955	4	is	be	VBZ
cord-022561-rv5j1201	1955	5	often	often	RB
cord-022561-rv5j1201	1955	6	present	present	JJ
cord-022561-rv5j1201	1955	7	in	in	IN
cord-022561-rv5j1201	1955	8	chronic	chronic	JJ
cord-022561-rv5j1201	1955	9	disease	disease	NN
cord-022561-rv5j1201	1955	10	conditions	condition	NNS
cord-022561-rv5j1201	1955	11	,	,	,
cord-022561-rv5j1201	1955	12	such	such	JJ
cord-022561-rv5j1201	1955	13	as	as	IN
cord-022561-rv5j1201	1955	14	BALT	BALT	NNP
cord-022561-rv5j1201	1955	15	hyperplasia	hyperplasia	NN
cord-022561-rv5j1201	1955	16	in	in	IN
cord-022561-rv5j1201	1955	17	chronic	chronic	JJ
cord-022561-rv5j1201	1955	18	Dictyocaulus	Dictyocaulus	NNP
cord-022561-rv5j1201	1955	19	spp	spp	NNS
cord-022561-rv5j1201	1955	20	.	.	.
cord-022561-rv5j1201	1956	1	(	(	-LRB-
cord-022561-rv5j1201	1956	2	horses	horse	NNS
cord-022561-rv5j1201	1956	3	,	,	,
cord-022561-rv5j1201	1956	4	cattle	cattle	NNS
cord-022561-rv5j1201	1956	5	,	,	,
cord-022561-rv5j1201	1956	6	sheep	sheep	NN
cord-022561-rv5j1201	1956	7	,	,	,
cord-022561-rv5j1201	1956	8	and	and	CC
cord-022561-rv5j1201	1956	9	goats	goat	NNS
cord-022561-rv5j1201	1956	10	)	)	-RRB-
cord-022561-rv5j1201	1956	11	or	or	CC
cord-022561-rv5j1201	1956	12	Metastrongylus	Metastrongylus	NNP
cord-022561-rv5j1201	1956	13	spp	spp	NNS
cord-022561-rv5j1201	1956	14	.	.	.
cord-022561-rv5j1201	1957	1	(	(	-LRB-
cord-022561-rv5j1201	1957	2	pigs	pig	NNS
cord-022561-rv5j1201	1957	3	)	)	-RRB-
cord-022561-rv5j1201	1957	4	associated	associate	VBD
cord-022561-rv5j1201	1957	5	bronchitis	bronchitis	NN
cord-022561-rv5j1201	1957	6	or	or	CC
cord-022561-rv5j1201	1957	7	bronchiolitis	bronchiolitis	NN
cord-022561-rv5j1201	1957	8	.	.	.
cord-022561-rv5j1201	1958	1	Mycoplasma	mycoplasma	NN
cord-022561-rv5j1201	1958	2	spp	spp	NNS
cord-022561-rv5j1201	1958	3	.	.	.
cord-022561-rv5j1201	1959	1	pneumonias	pneumonia	NNS
cord-022561-rv5j1201	1959	2	of	of	IN
cord-022561-rv5j1201	1959	3	sheep	sheep	NN
cord-022561-rv5j1201	1959	4	and	and	CC
cord-022561-rv5j1201	1960	1	pigs	pig	NNS
cord-022561-rv5j1201	1960	2	display	display	VBP
cord-022561-rv5j1201	1960	3	marked	mark	VBD
cord-022561-rv5j1201	1960	4	BALT	BALT	NNP
cord-022561-rv5j1201	1960	5	hyperplasia	hyperplasia	NN
cord-022561-rv5j1201	1960	6	that	that	WDT
cord-022561-rv5j1201	1960	7	can	can	MD
cord-022561-rv5j1201	1960	8	encircle	encircle	VB
cord-022561-rv5j1201	1960	9	bronchioles	bronchiole	NNS
cord-022561-rv5j1201	1960	10	and	and	CC
cord-022561-rv5j1201	1960	11	bronchi	bronchi	NN
cord-022561-rv5j1201	1960	12	(	(	-LRB-
cord-022561-rv5j1201	1960	13	"	"	``
cord-022561-rv5j1201	1960	14	cuffing	cuff	VBG
cord-022561-rv5j1201	1960	15	pneumonia	pneumonia	NN
cord-022561-rv5j1201	1960	16	"	"	''
cord-022561-rv5j1201	1960	17	)	)	-RRB-
cord-022561-rv5j1201	1960	18	.	.	.
cord-022561-rv5j1201	1961	1	Hyperplastic	hyperplastic	JJ
cord-022561-rv5j1201	1961	2	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	1961	3	nodules	nodule	NNS
cord-022561-rv5j1201	1961	4	can	can	MD
cord-022561-rv5j1201	1961	5	be	be	VB
cord-022561-rv5j1201	1961	6	so	so	RB
cord-022561-rv5j1201	1961	7	enlarged	enlarged	JJ
cord-022561-rv5j1201	1961	8	that	that	IN
cord-022561-rv5j1201	1961	9	they	-PRON-	PRP
cord-022561-rv5j1201	1961	10	become	become	VBP
cord-022561-rv5j1201	1961	11	grossly	grossly	RB
cord-022561-rv5j1201	1961	12	visible	visible	JJ
cord-022561-rv5j1201	1961	13	as	as	IN
cord-022561-rv5j1201	1961	14	discrete	discrete	JJ
cord-022561-rv5j1201	1961	15	white	white	JJ
cord-022561-rv5j1201	1961	16	plaques	plaque	NNS
cord-022561-rv5j1201	1961	17	or	or	CC
cord-022561-rv5j1201	1961	18	nodules	nodule	NNS
cord-022561-rv5j1201	1961	19	(	(	-LRB-
cord-022561-rv5j1201	1961	20	see	see	VB
cord-022561-rv5j1201	1961	21	Fig	Fig	NNP
cord-022561-rv5j1201	1961	22	.	.	.
cord-022561-rv5j1201	1961	23	 	 	_SP
cord-022561-rv5j1201	1962	1	13	13	CD
cord-022561-rv5j1201	1962	2	-51	-51	NN
cord-022561-rv5j1201	1962	3	,	,	,
cord-022561-rv5j1201	1962	4	A	A	NNP
cord-022561-rv5j1201	1962	5	)	)	-RRB-
cord-022561-rv5j1201	1962	6	.	.	.
cord-022561-rv5j1201	1963	1	They	-PRON-	PRP
cord-022561-rv5j1201	1963	2	can	can	MD
cord-022561-rv5j1201	1963	3	be	be	VB
cord-022561-rv5j1201	1963	4	seen	see	VBN
cord-022561-rv5j1201	1963	5	in	in	IN
cord-022561-rv5j1201	1963	6	the	the	DT
cord-022561-rv5j1201	1963	7	conjunctiva	conjunctiva	NN
cord-022561-rv5j1201	1963	8	of	of	IN
cord-022561-rv5j1201	1963	9	the	the	DT
cord-022561-rv5j1201	1963	10	eyelids	eyelid	NNS
cord-022561-rv5j1201	1963	11	and	and	CC
cord-022561-rv5j1201	1963	12	the	the	DT
cord-022561-rv5j1201	1963	13	third	third	JJ
cord-022561-rv5j1201	1963	14	eyelid	eyelid	NN
cord-022561-rv5j1201	1963	15	in	in	IN
cord-022561-rv5j1201	1963	16	chronic	chronic	JJ
cord-022561-rv5j1201	1963	17	conjunctivitis	conjunctivitis	NN
cord-022561-rv5j1201	1963	18	,	,	,
cord-022561-rv5j1201	1963	19	the	the	DT
cord-022561-rv5j1201	1963	20	pharyngeal	pharyngeal	JJ
cord-022561-rv5j1201	1963	21	mucosa	mucosa	JJ
cord-022561-rv5j1201	1963	22	in	in	IN
cord-022561-rv5j1201	1963	23	chronic	chronic	JJ
cord-022561-rv5j1201	1963	24	pharyngitis	pharyngitis	NN
cord-022561-rv5j1201	1963	25	,	,	,
cord-022561-rv5j1201	1963	26	the	the	DT
cord-022561-rv5j1201	1963	27	gastric	gastric	JJ
cord-022561-rv5j1201	1963	28	mucosa	mucosa	NN
cord-022561-rv5j1201	1963	29	in	in	IN
cord-022561-rv5j1201	1963	30	chronic	chronic	JJ
cord-022561-rv5j1201	1963	31	gastritis	gastritis	NN
cord-022561-rv5j1201	1963	32	,	,	,
cord-022561-rv5j1201	1963	33	and	and	CC
cord-022561-rv5j1201	1963	34	the	the	DT
cord-022561-rv5j1201	1963	35	urinary	urinary	JJ
cord-022561-rv5j1201	1963	36	bladder	bladder	NN
cord-022561-rv5j1201	1963	37	in	in	IN
cord-022561-rv5j1201	1963	38	chronic	chronic	JJ
cord-022561-rv5j1201	1963	39	cystitis	cystitis	NN
cord-022561-rv5j1201	1963	40	(	(	-LRB-
cord-022561-rv5j1201	1963	41	follicular	follicular	JJ
cord-022561-rv5j1201	1963	42	cystitis	cystitis	NN
cord-022561-rv5j1201	1963	43	)	)	-RRB-
cord-022561-rv5j1201	1963	44	.	.	.
cord-022561-rv5j1201	1964	1	The	the	DT
cord-022561-rv5j1201	1964	2	normal	normal	JJ
cord-022561-rv5j1201	1964	3	fetus	fetus	NN
cord-022561-rv5j1201	1964	4	has	have	VBZ
cord-022561-rv5j1201	1964	5	no	no	DT
cord-022561-rv5j1201	1964	6	detectable	detectable	JJ
cord-022561-rv5j1201	1964	7	BALT	BALT	NNP
cord-022561-rv5j1201	1964	8	,	,	,
cord-022561-rv5j1201	1964	9	though	though	IN
cord-022561-rv5j1201	1964	10	it	-PRON-	PRP
cord-022561-rv5j1201	1964	11	may	may	MD
cord-022561-rv5j1201	1964	12	be	be	VB
cord-022561-rv5j1201	1964	13	present	present	JJ
cord-022561-rv5j1201	1964	14	in	in	IN
cord-022561-rv5j1201	1964	15	fetuses	fetus	NNS
cord-022561-rv5j1201	1964	16	aborted	abort	VBN
cord-022561-rv5j1201	1964	17	due	due	JJ
cord-022561-rv5j1201	1964	18	to	to	IN
cord-022561-rv5j1201	1964	19	infectious	infectious	JJ
cord-022561-rv5j1201	1964	20	disease	disease	NN
cord-022561-rv5j1201	1964	21	.	.	.
cord-022561-rv5j1201	1965	1	Atrophy	atrophy	NN
cord-022561-rv5j1201	1965	2	.	.	.
cord-022561-rv5j1201	1966	1	Atrophy	atrophy	NN
cord-022561-rv5j1201	1966	2	of	of	IN
cord-022561-rv5j1201	1966	3	the	the	DT
cord-022561-rv5j1201	1966	4	diffuse	diffuse	JJ
cord-022561-rv5j1201	1966	5	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	1966	6	tissue	tissue	NN
cord-022561-rv5j1201	1966	7	and	and	CC
cord-022561-rv5j1201	1966	8	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	1966	9	nodules	nodule	NNS
cord-022561-rv5j1201	1966	10	has	have	VBZ
cord-022561-rv5j1201	1966	11	the	the	DT
cord-022561-rv5j1201	1966	12	same	same	JJ
cord-022561-rv5j1201	1966	13	causes	cause	NNS
cord-022561-rv5j1201	1966	14	as	as	IN
cord-022561-rv5j1201	1966	15	atrophy	atrophy	NN
cord-022561-rv5j1201	1966	16	affecting	affect	VBG
cord-022561-rv5j1201	1966	17	other	other	JJ
cord-022561-rv5j1201	1966	18	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	1966	19	tissues	tissue	NNS
cord-022561-rv5j1201	1966	20	(	(	-LRB-
cord-022561-rv5j1201	1966	21	see	see	VB
cord-022561-rv5j1201	1966	22	Box	Box	NNP
cord-022561-rv5j1201	1966	23	13	13	CD
cord-022561-rv5j1201	1966	24	-	-	SYM
cord-022561-rv5j1201	1966	25	5	5	CD
cord-022561-rv5j1201	1966	26	)	)	-RRB-
cord-022561-rv5j1201	1966	27	and	and	CC
cord-022561-rv5j1201	1966	28	includes	include	VBZ
cord-022561-rv5j1201	1966	29	lack	lack	NN
cord-022561-rv5j1201	1966	30	of	of	IN
cord-022561-rv5j1201	1966	31	antigenic	antigenic	JJ
cord-022561-rv5j1201	1966	32	stimulation	stimulation	NN
cord-022561-rv5j1201	1966	33	,	,	,
cord-022561-rv5j1201	1966	34	cachexia	cachexia	NN
cord-022561-rv5j1201	1966	35	,	,	,
cord-022561-rv5j1201	1966	36	malnutrition	malnutrition	NN
cord-022561-rv5j1201	1966	37	,	,	,
cord-022561-rv5j1201	1966	38	aging	age	VBG
cord-022561-rv5j1201	1966	39	,	,	,
cord-022561-rv5j1201	1966	40	viral	viral	JJ
cord-022561-rv5j1201	1966	41	infections	infection	NNS
cord-022561-rv5j1201	1966	42	,	,	,
cord-022561-rv5j1201	1966	43	or	or	CC
cord-022561-rv5j1201	1966	44	failure	failure	NN
cord-022561-rv5j1201	1966	45	to	to	TO
cord-022561-rv5j1201	1966	46	be	be	VB
cord-022561-rv5j1201	1966	47	repopulated	repopulate	VBN
cord-022561-rv5j1201	1966	48	by	by	IN
cord-022561-rv5j1201	1966	49	B	b	NN
cord-022561-rv5j1201	1966	50	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	1966	51	from	from	IN
cord-022561-rv5j1201	1966	52	the	the	DT
cord-022561-rv5j1201	1966	53	bone	bone	NN
cord-022561-rv5j1201	1966	54	marrow	marrow	NN
cord-022561-rv5j1201	1966	55	or	or	CC
cord-022561-rv5j1201	1966	56	T	t	NN
cord-022561-rv5j1201	1966	57	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	1966	58	from	from	IN
cord-022561-rv5j1201	1966	59	the	the	DT
cord-022561-rv5j1201	1966	60	thymus	thymus	NN
cord-022561-rv5j1201	1966	61	.	.	.
cord-022561-rv5j1201	1967	1	Lymphocytolysis	Lymphocytolysis	NNP
cord-022561-rv5j1201	1967	2	of	of	IN
cord-022561-rv5j1201	1967	3	germinal	germinal	JJ
cord-022561-rv5j1201	1967	4	center	center	NN
cord-022561-rv5j1201	1967	5	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	1967	6	of	of	IN
cord-022561-rv5j1201	1967	7	Peyer	Peyer	NNP
cord-022561-rv5j1201	1967	8	's	's	POS
cord-022561-rv5j1201	1967	9	patches	patch	NNS
cord-022561-rv5j1201	1967	10	is	be	VBZ
cord-022561-rv5j1201	1967	11	a	a	DT
cord-022561-rv5j1201	1967	12	characteristic	characteristic	JJ
cord-022561-rv5j1201	1967	13	lesion	lesion	NN
cord-022561-rv5j1201	1967	14	in	in	IN
cord-022561-rv5j1201	1967	15	BVDV	BVDV	NNP
cord-022561-rv5j1201	1967	16	infection	infection	NN
cord-022561-rv5j1201	1967	17	in	in	IN
cord-022561-rv5j1201	1967	18	ruminants	ruminant	NNS
cord-022561-rv5j1201	1967	19	and	and	CC
cord-022561-rv5j1201	1967	20	canine	canine	JJ
cord-022561-rv5j1201	1967	21	and	and	CC
cord-022561-rv5j1201	1967	22	feline	feline	JJ
cord-022561-rv5j1201	1967	23	parvovirus	parvovirus	NN
cord-022561-rv5j1201	1967	24	infections	infection	NNS
cord-022561-rv5j1201	1967	25	(	(	-LRB-
cord-022561-rv5j1201	1967	26	"	"	''
cord-022561-rv5j1201	1967	27	punchedout	punchedout	NNP
cord-022561-rv5j1201	1967	28	Peyer	Peyer	NNP
cord-022561-rv5j1201	1967	29	's	's	POS
cord-022561-rv5j1201	1967	30	patches	patch	NNS
cord-022561-rv5j1201	1967	31	)	)	-RRB-
cord-022561-rv5j1201	1968	1	(	(	-LRB-
cord-022561-rv5j1201	1968	2	see	see	VB
cord-022561-rv5j1201	1968	3	Chapters	Chapters	NNPS
cord-022561-rv5j1201	1968	4	4	4	CD
cord-022561-rv5j1201	1968	5	and	and	CC
cord-022561-rv5j1201	1968	6	7	7	CD
cord-022561-rv5j1201	1968	7	)	)	-RRB-
cord-022561-rv5j1201	1968	8	.	.	.
cord-022561-rv5j1201	1969	1	The	the	DT
cord-022561-rv5j1201	1969	2	main	main	JJ
cord-022561-rv5j1201	1969	3	portals	portal	NNS
cord-022561-rv5j1201	1969	4	of	of	IN
cord-022561-rv5j1201	1969	5	entry	entry	NN
cord-022561-rv5j1201	1969	6	to	to	IN
cord-022561-rv5j1201	1969	7	MALT	malt	NN
cord-022561-rv5j1201	1969	8	for	for	IN
cord-022561-rv5j1201	1969	9	infectious	infectious	JJ
cord-022561-rv5j1201	1969	10	agents	agent	NNS
cord-022561-rv5j1201	1969	11	are	be	VBP
cord-022561-rv5j1201	1969	12	hematogenous	hematogenous	JJ
cord-022561-rv5j1201	1969	13	spread	spread	NN
cord-022561-rv5j1201	1969	14	and	and	CC
cord-022561-rv5j1201	1969	15	through	through	IN
cord-022561-rv5j1201	1969	16	migrating	migrate	VBG
cord-022561-rv5j1201	1969	17	macrophages	macrophage	NNS
cord-022561-rv5j1201	1969	18	,	,	,
cord-022561-rv5j1201	1969	19	DCs	dc	NNS
cord-022561-rv5j1201	1969	20	,	,	,
cord-022561-rv5j1201	1969	21	and	and	CC
cord-022561-rv5j1201	1969	22	M	M	NNP
cord-022561-rv5j1201	1969	23	cells	cell	NNS
cord-022561-rv5j1201	1969	24	.	.	.
cord-022561-rv5j1201	1970	1	Pathogenic	pathogenic	JJ
cord-022561-rv5j1201	1970	2	bacteria	bacteria	NNS
cord-022561-rv5j1201	1970	3	such	such	JJ
cord-022561-rv5j1201	1970	4	as	as	IN
cord-022561-rv5j1201	1970	5	Escherichia	Escherichia	NNP
cord-022561-rv5j1201	1970	6	coli	coli	NNS
cord-022561-rv5j1201	1970	7	,	,	,
cord-022561-rv5j1201	1970	8	Yersinia	Yersinia	NNP
cord-022561-rv5j1201	1970	9	pestis	pestis	NN
cord-022561-rv5j1201	1970	10	,	,	,
cord-022561-rv5j1201	1970	11	Mycobacterium	Mycobacterium	NNP
cord-022561-rv5j1201	1970	12	avium	avium	NN
cord-022561-rv5j1201	1970	13	ssp	ssp	NN
cord-022561-rv5j1201	1970	14	.	.	.
cord-022561-rv5j1201	1971	1	paratuberculosis	paratuberculosis	NNP
cord-022561-rv5j1201	1971	2	(	(	-LRB-
cord-022561-rv5j1201	1971	3	MAP	MAP	NNP
cord-022561-rv5j1201	1971	4	)	)	-RRB-
cord-022561-rv5j1201	1971	5	,	,	,
cord-022561-rv5j1201	1971	6	L.	L.	NNP
cord-022561-rv5j1201	1971	7	monocytogenes	monocytogenes	NNP
cord-022561-rv5j1201	1971	8	,	,	,
cord-022561-rv5j1201	1971	9	Salmonella	Salmonella	NNP
cord-022561-rv5j1201	1971	10	spp	spp	NNS
cord-022561-rv5j1201	1971	11	.	.	.
cord-022561-rv5j1201	1972	1	,	,	,
cord-022561-rv5j1201	1972	2	and	and	CC
cord-022561-rv5j1201	1972	3	Shigella	Shigella	NNP
cord-022561-rv5j1201	1972	4	flexneri	flexneri	NN
cord-022561-rv5j1201	1972	5	can	can	MD
cord-022561-rv5j1201	1972	6	invade	invade	VB
cord-022561-rv5j1201	1972	7	the	the	DT
cord-022561-rv5j1201	1972	8	host	host	NN
cord-022561-rv5j1201	1972	9	from	from	IN
cord-022561-rv5j1201	1972	10	the	the	DT
cord-022561-rv5j1201	1972	11	lumen	lumen	NN
cord-022561-rv5j1201	1972	12	of	of	IN
cord-022561-rv5j1201	1972	13	the	the	DT
cord-022561-rv5j1201	1972	14	intestine	intestine	NN
cord-022561-rv5j1201	1972	15	through	through	IN
cord-022561-rv5j1201	1972	16	dendritic	dendritic	JJ
cord-022561-rv5j1201	1972	17	or	or	CC
cord-022561-rv5j1201	1972	18	M	m	CD
cord-022561-rv5j1201	1972	19	cells	cell	NNS
cord-022561-rv5j1201	1972	20	.	.	.
cord-022561-rv5j1201	1973	1	Some	some	DT
cord-022561-rv5j1201	1973	2	viruses	virus	NNS
cord-022561-rv5j1201	1973	3	(	(	-LRB-
cord-022561-rv5j1201	1973	4	e.g.	e.g.	RB
cord-022561-rv5j1201	1973	5	,	,	,
cord-022561-rv5j1201	1973	6	reovirus	reovirus	NNP
cord-022561-rv5j1201	1973	7	)	)	-RRB-
cord-022561-rv5j1201	1973	8	may	may	MD
cord-022561-rv5j1201	1973	9	be	be	VB
cord-022561-rv5j1201	1973	10	transported	transport	VBN
cord-022561-rv5j1201	1973	11	by	by	IN
cord-022561-rv5j1201	1973	12	M	M	NNP
cord-022561-rv5j1201	1973	13	cells	cell	NNS
cord-022561-rv5j1201	1973	14	.	.	.
cord-022561-rv5j1201	1974	1	The	the	DT
cord-022561-rv5j1201	1974	2	scrapie	scrapie	NN
cord-022561-rv5j1201	1974	3	prion	prion	NN
cord-022561-rv5j1201	1974	4	protein	protein	NN
cord-022561-rv5j1201	1974	5	(	(	-LRB-
cord-022561-rv5j1201	1974	6	PrP	PrP	NNP
cord-022561-rv5j1201	1974	7	Sc	Sc	NNP
cord-022561-rv5j1201	1974	8	)	)	-RRB-
cord-022561-rv5j1201	1974	9	may	may	MD
cord-022561-rv5j1201	1974	10	also	also	RB
cord-022561-rv5j1201	1974	11	accumulate	accumulate	VB
cord-022561-rv5j1201	1974	12	in	in	IN
cord-022561-rv5j1201	1974	13	Peyer	Peyer	NNP
cord-022561-rv5j1201	1974	14	's	's	POS
cord-022561-rv5j1201	1974	15	patches	patch	NNS
cord-022561-rv5j1201	1974	16	.	.	.
cord-022561-rv5j1201	1975	1	Many	many	JJ
cord-022561-rv5j1201	1975	2	viruses	virus	NNS
cord-022561-rv5j1201	1975	3	,	,	,
cord-022561-rv5j1201	1975	4	such	such	JJ
cord-022561-rv5j1201	1975	5	as	as	IN
cord-022561-rv5j1201	1975	6	bovine	bovine	JJ
cord-022561-rv5j1201	1975	7	coronavirus	coronavirus	NN
cord-022561-rv5j1201	1975	8	,	,	,
cord-022561-rv5j1201	1975	9	BVDV	BVDV	NNP
cord-022561-rv5j1201	1975	10	,	,	,
cord-022561-rv5j1201	1975	11	rinderpest	rinderpest	NN
cord-022561-rv5j1201	1975	12	virus	virus	NN
cord-022561-rv5j1201	1975	13	,	,	,
cord-022561-rv5j1201	1975	14	malignant	malignant	JJ
cord-022561-rv5j1201	1975	15	catarrhal	catarrhal	NN
cord-022561-rv5j1201	1975	16	fever	fever	NN
cord-022561-rv5j1201	1975	17	virus	virus	NN
cord-022561-rv5j1201	1975	18	,	,	,
cord-022561-rv5j1201	1975	19	feline	feline	JJ
cord-022561-rv5j1201	1975	20	panleukopenia	panleukopenia	NNP
cord-022561-rv5j1201	1975	21	virus	virus	NN
cord-022561-rv5j1201	1975	22	,	,	,
cord-022561-rv5j1201	1975	23	and	and	CC
cord-022561-rv5j1201	1975	24	canine	canine	JJ
cord-022561-rv5j1201	1975	25	parvovirus	parvovirus	NN
cord-022561-rv5j1201	1975	26	,	,	,
cord-022561-rv5j1201	1975	27	cause	cause	VB
cord-022561-rv5j1201	1975	28	lymphocyte	lymphocyte	NN
cord-022561-rv5j1201	1975	29	depletion	depletion	NN
cord-022561-rv5j1201	1975	30	within	within	IN
cord-022561-rv5j1201	1975	31	the	the	DT
cord-022561-rv5j1201	1975	32	MALT	malt	NN
cord-022561-rv5j1201	1975	33	.	.	.
cord-022561-rv5j1201	1976	1	Portals	portal	NNS
cord-022561-rv5j1201	1976	2	of	of	IN
cord-022561-rv5j1201	1976	3	entry	entry	NN
cord-022561-rv5j1201	1976	4	used	use	VBN
cord-022561-rv5j1201	1976	5	by	by	IN
cord-022561-rv5j1201	1976	6	microorganisms	microorganism	NNS
cord-022561-rv5j1201	1976	7	and	and	CC
cord-022561-rv5j1201	1976	8	other	other	JJ
cord-022561-rv5j1201	1976	9	agents	agent	NNS
cord-022561-rv5j1201	1976	10	and	and	CC
cord-022561-rv5j1201	1976	11	substances	substance	NNS
cord-022561-rv5j1201	1976	12	to	to	TO
cord-022561-rv5j1201	1976	13	access	access	VB
cord-022561-rv5j1201	1976	14	the	the	DT
cord-022561-rv5j1201	1976	15	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	1976	16	system	system	NN
cord-022561-rv5j1201	1976	17	are	be	VBP
cord-022561-rv5j1201	1976	18	summarized	summarize	VBN
cord-022561-rv5j1201	1976	19	in	in	IN
cord-022561-rv5j1201	1976	20	Box	Box	NNP
cord-022561-rv5j1201	1976	21	13	13	CD
cord-022561-rv5j1201	1976	22	-	-	SYM
cord-022561-rv5j1201	1976	23	6	6	CD
cord-022561-rv5j1201	1976	24	.	.	.
cord-022561-rv5j1201	1977	1	Defense	defense	NN
cord-022561-rv5j1201	1977	2	mechanisms	mechanism	NNS
cord-022561-rv5j1201	1977	3	used	use	VBN
cord-022561-rv5j1201	1977	4	by	by	IN
cord-022561-rv5j1201	1977	5	MALT	malt	NN
cord-022561-rv5j1201	1977	6	to	to	TO
cord-022561-rv5j1201	1977	7	protect	protect	VB
cord-022561-rv5j1201	1977	8	itself	-PRON-	PRP
cord-022561-rv5j1201	1977	9	against	against	IN
cord-022561-rv5j1201	1977	10	microorganisms	microorganism	NNS
cord-022561-rv5j1201	1977	11	and	and	CC
cord-022561-rv5j1201	1977	12	other	other	JJ
cord-022561-rv5j1201	1977	13	agents	agent	NNS
cord-022561-rv5j1201	1977	14	are	be	VBP
cord-022561-rv5j1201	1977	15	the	the	DT
cord-022561-rv5j1201	1977	16	innate	innate	JJ
cord-022561-rv5j1201	1977	17	and	and	CC
cord-022561-rv5j1201	1977	18	adaptive	adaptive	JJ
cord-022561-rv5j1201	1977	19	immune	immune	JJ
cord-022561-rv5j1201	1977	20	responses	response	NNS
cord-022561-rv5j1201	1977	21	,	,	,
cord-022561-rv5j1201	1977	22	discussed	discuss	VBN
cord-022561-rv5j1201	1977	23	in	in	IN
cord-022561-rv5j1201	1977	24	Chapters	chapter	NNS
cord-022561-rv5j1201	1977	25	3	3	CD
cord-022561-rv5j1201	1977	26	,	,	,
cord-022561-rv5j1201	1977	27	4	4	CD
cord-022561-rv5j1201	1977	28	,	,	,
cord-022561-rv5j1201	1977	29	and	and	CC
cord-022561-rv5j1201	1977	30	5	5	CD
cord-022561-rv5j1201	1977	31	.	.	.
cord-022561-rv5j1201	1978	1	Congenital	congenital	JJ
cord-022561-rv5j1201	1978	2	disorders	disorder	NNS
cord-022561-rv5j1201	1978	3	of	of	IN
cord-022561-rv5j1201	1978	4	the	the	DT
cord-022561-rv5j1201	1978	5	thymus	thymus	NN
cord-022561-rv5j1201	1978	6	are	be	VBP
cord-022561-rv5j1201	1978	7	discussed	discuss	VBN
cord-022561-rv5j1201	1978	8	in	in	IN
cord-022561-rv5j1201	1978	9	detail	detail	NN
cord-022561-rv5j1201	1978	10	in	in	IN
cord-022561-rv5j1201	1978	11	Chapter	chapter	NN
cord-022561-rv5j1201	1978	12	5	5	CD
cord-022561-rv5j1201	1978	13	.	.	.
cord-022561-rv5j1201	1979	1	Summaries	summary	NNS
cord-022561-rv5j1201	1979	2	of	of	IN
cord-022561-rv5j1201	1979	3	the	the	DT
cord-022561-rv5j1201	1979	4	gross	gross	JJ
cord-022561-rv5j1201	1979	5	and	and	CC
cord-022561-rv5j1201	1979	6	microscopic	microscopic	JJ
cord-022561-rv5j1201	1979	7	morphologic	morphologic	JJ
cord-022561-rv5j1201	1979	8	changes	change	NNS
cord-022561-rv5j1201	1979	9	are	be	VBP
cord-022561-rv5j1201	1979	10	Solitary	solitary	JJ
cord-022561-rv5j1201	1979	11	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	1979	12	nodules	nodule	NNS
cord-022561-rv5j1201	1979	13	are	be	VBP
cord-022561-rv5j1201	1979	14	localized	localize	VBN
cord-022561-rv5j1201	1979	15	concentrations	concentration	NNS
cord-022561-rv5j1201	1979	16	of	of	IN
cord-022561-rv5j1201	1979	17	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	1979	18	(	(	-LRB-
cord-022561-rv5j1201	1979	19	mainly	mainly	RB
cord-022561-rv5j1201	1979	20	B	b	NN
cord-022561-rv5j1201	1979	21	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	1979	22	)	)	-RRB-
cord-022561-rv5j1201	1979	23	in	in	IN
cord-022561-rv5j1201	1979	24	the	the	DT
cord-022561-rv5j1201	1979	25	mucosa	mucosa	NN
cord-022561-rv5j1201	1979	26	and	and	CC
cord-022561-rv5j1201	1979	27	consist	consist	VBP
cord-022561-rv5j1201	1979	28	of	of	IN
cord-022561-rv5j1201	1979	29	defined	define	VBN
cord-022561-rv5j1201	1979	30	but	but	CC
cord-022561-rv5j1201	1979	31	unencapsulated	unencapsulated	JJ
cord-022561-rv5j1201	1979	32	clusters	cluster	NNS
cord-022561-rv5j1201	1979	33	of	of	IN
cord-022561-rv5j1201	1979	34	small	small	JJ
cord-022561-rv5j1201	1979	35	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	1979	36	(	(	-LRB-
cord-022561-rv5j1201	1979	37	primary	primary	JJ
cord-022561-rv5j1201	1979	38	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	1979	39	nodule	nodule	NN
cord-022561-rv5j1201	1979	40	)	)	-RRB-
cord-022561-rv5j1201	1979	41	.	.	.
cord-022561-rv5j1201	1980	1	They	-PRON-	PRP
cord-022561-rv5j1201	1980	2	are	be	VBP
cord-022561-rv5j1201	1980	3	usually	usually	RB
cord-022561-rv5j1201	1980	4	not	not	RB
cord-022561-rv5j1201	1980	5	grossly	grossly	RB
cord-022561-rv5j1201	1980	6	visible	visible	JJ
cord-022561-rv5j1201	1980	7	in	in	IN
cord-022561-rv5j1201	1980	8	the	the	DT
cord-022561-rv5j1201	1980	9	resting	resting	NN
cord-022561-rv5j1201	1980	10	or	or	CC
cord-022561-rv5j1201	1980	11	antigenically	antigenically	RB
cord-022561-rv5j1201	1980	12	unstimulated	unstimulated	JJ
cord-022561-rv5j1201	1980	13	state	state	NN
cord-022561-rv5j1201	1980	14	,	,	,
cord-022561-rv5j1201	1980	15	but	but	CC
cord-022561-rv5j1201	1980	16	upon	upon	IN
cord-022561-rv5j1201	1980	17	antigenic	antigenic	JJ
cord-022561-rv5j1201	1980	18	stimulation	stimulation	NN
cord-022561-rv5j1201	1980	19	,	,	,
cord-022561-rv5j1201	1980	20	they	-PRON-	PRP
cord-022561-rv5j1201	1980	21	proliferate	proliferate	VBP
cord-022561-rv5j1201	1980	22	and	and	CC
cord-022561-rv5j1201	1980	23	form	form	VBP
cord-022561-rv5j1201	1980	24	germinal	germinal	JJ
cord-022561-rv5j1201	1980	25	centers	center	NNS
cord-022561-rv5j1201	1980	26	and	and	CC
cord-022561-rv5j1201	1980	27	surrounding	surround	VBG
cord-022561-rv5j1201	1980	28	mantle	mantle	NN
cord-022561-rv5j1201	1980	29	cell	cell	NN
cord-022561-rv5j1201	1980	30	zones	zone	NNS
cord-022561-rv5j1201	1980	31	(	(	-LRB-
cord-022561-rv5j1201	1980	32	secondary	secondary	JJ
cord-022561-rv5j1201	1980	33	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	1980	34	nodules	nodule	NNS
cord-022561-rv5j1201	1980	35	)	)	-RRB-
cord-022561-rv5j1201	1980	36	.	.	.
cord-022561-rv5j1201	1981	1	Aggregated	aggregated	JJ
cord-022561-rv5j1201	1981	2	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	1981	3	nodules	nodule	NNS
cord-022561-rv5j1201	1981	4	consist	consist	VBP
cord-022561-rv5j1201	1981	5	of	of	IN
cord-022561-rv5j1201	1981	6	groups	group	NNS
cord-022561-rv5j1201	1981	7	of	of	IN
cord-022561-rv5j1201	1981	8	lymph	lymph	NN
cord-022561-rv5j1201	1981	9	nodules	nodule	NNS
cord-022561-rv5j1201	1981	10	,	,	,
cord-022561-rv5j1201	1981	11	the	the	DT
cord-022561-rv5j1201	1981	12	most	most	RBS
cord-022561-rv5j1201	1981	13	notable	notable	JJ
cord-022561-rv5j1201	1981	14	of	of	IN
cord-022561-rv5j1201	1981	15	which	which	WDT
cord-022561-rv5j1201	1981	16	are	be	VBP
cord-022561-rv5j1201	1981	17	the	the	DT
cord-022561-rv5j1201	1981	18	tonsils	tonsil	NNS
cord-022561-rv5j1201	1981	19	and	and	CC
cord-022561-rv5j1201	1981	20	Peyer	Peyer	NNP
cord-022561-rv5j1201	1981	21	's	's	POS
cord-022561-rv5j1201	1981	22	patches	patch	NNS
cord-022561-rv5j1201	1981	23	.	.	.
cord-022561-rv5j1201	1982	1	The	the	DT
cord-022561-rv5j1201	1982	2	aggregated	aggregated	JJ
cord-022561-rv5j1201	1982	3	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	1982	4	follicles	follicle	NNS
cord-022561-rv5j1201	1982	5	of	of	IN
cord-022561-rv5j1201	1982	6	the	the	DT
cord-022561-rv5j1201	1982	7	Peyer	Peyer	NNP
cord-022561-rv5j1201	1982	8	's	's	POS
cord-022561-rv5j1201	1982	9	patches	patch	NNS
cord-022561-rv5j1201	1982	10	are	be	VBP
cord-022561-rv5j1201	1982	11	most	most	RBS
cord-022561-rv5j1201	1982	12	obvious	obvious	JJ
cord-022561-rv5j1201	1982	13	in	in	IN
cord-022561-rv5j1201	1982	14	the	the	DT
cord-022561-rv5j1201	1982	15	ileum	ileum	NN
cord-022561-rv5j1201	1982	16	.	.	.
cord-022561-rv5j1201	1983	1	The	the	DT
cord-022561-rv5j1201	1983	2	latter	latter	JJ
cord-022561-rv5j1201	1983	3	are	be	VBP
cord-022561-rv5j1201	1983	4	covered	cover	VBN
cord-022561-rv5j1201	1983	5	by	by	IN
cord-022561-rv5j1201	1983	6	a	a	DT
cord-022561-rv5j1201	1983	7	specialized	specialized	JJ
cord-022561-rv5j1201	1983	8	epithelium	epithelium	NN
cord-022561-rv5j1201	1983	9	,	,	,
cord-022561-rv5j1201	1983	10	the	the	DT
cord-022561-rv5j1201	1983	11	follicle	follicle	NN
cord-022561-rv5j1201	1983	12	-	-	HYPH
cord-022561-rv5j1201	1983	13	associated	associate	VBN
cord-022561-rv5j1201	1983	14	epithelium	epithelium	NN
cord-022561-rv5j1201	1983	15	(	(	-LRB-
cord-022561-rv5j1201	1983	16	FAE	FAE	NNP
cord-022561-rv5j1201	1983	17	)	)	-RRB-
cord-022561-rv5j1201	1983	18	.	.	.
cord-022561-rv5j1201	1984	1	The	the	DT
cord-022561-rv5j1201	1984	2	FAE	FAE	NNP
cord-022561-rv5j1201	1984	3	is	be	VBZ
cord-022561-rv5j1201	1984	4	the	the	DT
cord-022561-rv5j1201	1984	5	interface	interface	NN
cord-022561-rv5j1201	1984	6	between	between	IN
cord-022561-rv5j1201	1984	7	the	the	DT
cord-022561-rv5j1201	1984	8	Peyer	Peyer	NNP
cord-022561-rv5j1201	1984	9	's	's	POS
cord-022561-rv5j1201	1984	10	patches	patch	NNS
cord-022561-rv5j1201	1984	11	and	and	CC
cord-022561-rv5j1201	1984	12	the	the	DT
cord-022561-rv5j1201	1984	13	luminal	luminal	JJ
cord-022561-rv5j1201	1984	14	microenvironment	microenvironment	NN
cord-022561-rv5j1201	1984	15	and	and	CC
cord-022561-rv5j1201	1984	16	consists	consist	VBZ
cord-022561-rv5j1201	1984	17	of	of	IN
cord-022561-rv5j1201	1984	18	enterocytes	enterocytes	NNP
cord-022561-rv5j1201	1984	19	and	and	CC
cord-022561-rv5j1201	1984	20	interdigitated	interdigitated	NNP
cord-022561-rv5j1201	1984	21	M	M	NNP
cord-022561-rv5j1201	1984	22	cells	cell	NNS
cord-022561-rv5j1201	1984	23	.	.	.
cord-022561-rv5j1201	1985	1	M	M	NNP
cord-022561-rv5j1201	1985	2	cells	cell	NNS
cord-022561-rv5j1201	1985	3	transport	transport	VBP
cord-022561-rv5j1201	1985	4	(	(	-LRB-
cord-022561-rv5j1201	1985	5	via	via	IN
cord-022561-rv5j1201	1985	6	endocytosis	endocytosis	NN
cord-022561-rv5j1201	1985	7	,	,	,
cord-022561-rv5j1201	1985	8	phagocytosis	phagocytosis	NN
cord-022561-rv5j1201	1985	9	,	,	,
cord-022561-rv5j1201	1985	10	pinocytosis	pinocytosis	NN
cord-022561-rv5j1201	1985	11	,	,	,
cord-022561-rv5j1201	1985	12	and	and	CC
cord-022561-rv5j1201	1985	13	micropinocytosis	micropinocytosis	NNP
cord-022561-rv5j1201	1985	14	)	)	-RRB-
cord-022561-rv5j1201	1985	15	antigens	antigen	NNS
cord-022561-rv5j1201	1985	16	,	,	,
cord-022561-rv5j1201	1985	17	particles	particle	NNS
cord-022561-rv5j1201	1985	18	,	,	,
cord-022561-rv5j1201	1985	19	bacteria	bacteria	NNS
cord-022561-rv5j1201	1985	20	,	,	,
cord-022561-rv5j1201	1985	21	and	and	CC
cord-022561-rv5j1201	1985	22	viruses	virus	NNS
cord-022561-rv5j1201	1985	23	from	from	IN
cord-022561-rv5j1201	1985	24	the	the	DT
cord-022561-rv5j1201	1985	25	intestinal	intestinal	JJ
cord-022561-rv5j1201	1985	26	lumen	lumen	NN
cord-022561-rv5j1201	1985	27	to	to	IN
cord-022561-rv5j1201	1985	28	the	the	DT
cord-022561-rv5j1201	1985	29	underlying	underlying	JJ
cord-022561-rv5j1201	1985	30	area	area	NN
cord-022561-rv5j1201	1985	31	rich	rich	JJ
cord-022561-rv5j1201	1985	32	in	in	IN
cord-022561-rv5j1201	1985	33	DCs	DCs	NNP
cord-022561-rv5j1201	1985	34	,	,	,
cord-022561-rv5j1201	1985	35	which	which	WDT
cord-022561-rv5j1201	1985	36	deliver	deliver	VBP
cord-022561-rv5j1201	1985	37	the	the	DT
cord-022561-rv5j1201	1985	38	material	material	NN
cord-022561-rv5j1201	1985	39	to	to	IN
cord-022561-rv5j1201	1985	40	the	the	DT
cord-022561-rv5j1201	1985	41	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	1985	42	tissue	tissue	NN
cord-022561-rv5j1201	1985	43	of	of	IN
cord-022561-rv5j1201	1985	44	the	the	DT
cord-022561-rv5j1201	1985	45	Peyer	Peyer	NNP
cord-022561-rv5j1201	1985	46	's	's	POS
cord-022561-rv5j1201	1985	47	patches	patch	NNS
cord-022561-rv5j1201	1985	48	.	.	.
cord-022561-rv5j1201	1986	1	M	m	NN
cord-022561-rv5j1201	1986	2	cells	cell	NNS
cord-022561-rv5j1201	1986	3	also	also	RB
cord-022561-rv5j1201	1986	4	express	express	VBP
cord-022561-rv5j1201	1986	5	IgA	IgA	NNP
cord-022561-rv5j1201	1986	6	receptors	receptor	NNS
cord-022561-rv5j1201	1986	7	,	,	,
cord-022561-rv5j1201	1986	8	which	which	WDT
cord-022561-rv5j1201	1986	9	allows	allow	VBZ
cord-022561-rv5j1201	1986	10	for	for	IN
cord-022561-rv5j1201	1986	11	the	the	DT
cord-022561-rv5j1201	1986	12	capture	capture	NN
cord-022561-rv5j1201	1986	13	and	and	CC
cord-022561-rv5j1201	1986	14	transport	transport	NN
cord-022561-rv5j1201	1986	15	of	of	IN
cord-022561-rv5j1201	1986	16	bacteria	bacteria	NNS
cord-022561-rv5j1201	1986	17	entrapped	entrap	VBN
cord-022561-rv5j1201	1986	18	by	by	IN
cord-022561-rv5j1201	1986	19	IgA.	IgA.	NNP
cord-022561-rv5j1201	1986	20	The	the	DT
cord-022561-rv5j1201	1986	21	proportion	proportion	NN
cord-022561-rv5j1201	1986	22	of	of	IN
cord-022561-rv5j1201	1986	23	enterocytes	enterocyte	NNS
cord-022561-rv5j1201	1986	24	and	and	CC
cord-022561-rv5j1201	1986	25	M	M	NNP
cord-022561-rv5j1201	1986	26	cells	cell	NNS
cord-022561-rv5j1201	1986	27	within	within	IN
cord-022561-rv5j1201	1986	28	the	the	DT
cord-022561-rv5j1201	1986	29	FAE	FAE	NNP
cord-022561-rv5j1201	1986	30	is	be	VBZ
cord-022561-rv5j1201	1986	31	modulated	modulate	VBN
cord-022561-rv5j1201	1986	32	by	by	IN
cord-022561-rv5j1201	1986	33	the	the	DT
cord-022561-rv5j1201	1986	34	luminal	luminal	JJ
cord-022561-rv5j1201	1986	35	bacterial	bacterial	JJ
cord-022561-rv5j1201	1986	36	A	a	DT
cord-022561-rv5j1201	1986	37	B	B	NNP
cord-022561-rv5j1201	1986	38	mercury	mercury	NN
cord-022561-rv5j1201	1986	39	have	have	VBP
cord-022561-rv5j1201	1986	40	a	a	DT
cord-022561-rv5j1201	1986	41	suppressive	suppressive	JJ
cord-022561-rv5j1201	1986	42	effect	effect	NN
cord-022561-rv5j1201	1986	43	on	on	IN
cord-022561-rv5j1201	1986	44	the	the	DT
cord-022561-rv5j1201	1986	45	immune	immune	JJ
cord-022561-rv5j1201	1986	46	system	system	NN
cord-022561-rv5j1201	1986	47	.	.	.
cord-022561-rv5j1201	1987	1	Halogenated	halogenated	JJ
cord-022561-rv5j1201	1987	2	aromatic	aromatic	JJ
cord-022561-rv5j1201	1987	3	hydrocarbons	hydrocarbon	NNS
cord-022561-rv5j1201	1987	4	cause	cause	VBP
cord-022561-rv5j1201	1987	5	dysfunction	dysfunction	NN
cord-022561-rv5j1201	1987	6	of	of	IN
cord-022561-rv5j1201	1987	7	DCs	dc	NNS
cord-022561-rv5j1201	1987	8	through	through	IN
cord-022561-rv5j1201	1987	9	several	several	JJ
cord-022561-rv5j1201	1987	10	mechanisms	mechanism	NNS
cord-022561-rv5j1201	1987	11	that	that	WDT
cord-022561-rv5j1201	1987	12	lead	lead	VBP
cord-022561-rv5j1201	1987	13	to	to	IN
cord-022561-rv5j1201	1987	14	atrophy	atrophy	NN
cord-022561-rv5j1201	1987	15	of	of	IN
cord-022561-rv5j1201	1987	16	the	the	DT
cord-022561-rv5j1201	1987	17	primary	primary	JJ
cord-022561-rv5j1201	1987	18	and	and	CC
cord-022561-rv5j1201	1987	19	secondary	secondary	JJ
cord-022561-rv5j1201	1987	20	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	1987	21	organs	organ	NNS
cord-022561-rv5j1201	1987	22	.	.	.
cord-022561-rv5j1201	1988	1	Heavy	heavy	JJ
cord-022561-rv5j1201	1988	2	metals	metal	NNS
cord-022561-rv5j1201	1988	3	,	,	,
cord-022561-rv5j1201	1988	4	such	such	JJ
cord-022561-rv5j1201	1988	5	as	as	IN
cord-022561-rv5j1201	1988	6	lead	lead	NN
cord-022561-rv5j1201	1988	7	,	,	,
cord-022561-rv5j1201	1988	8	mercury	mercury	NN
cord-022561-rv5j1201	1988	9	and	and	CC
cord-022561-rv5j1201	1988	10	nickel	nickel	NN
cord-022561-rv5j1201	1988	11	,	,	,
cord-022561-rv5j1201	1988	12	are	be	VBP
cord-022561-rv5j1201	1988	13	immunosuppressive	immunosuppressive	JJ
cord-022561-rv5j1201	1988	14	and	and	CC
cord-022561-rv5j1201	1988	15	generally	generally	RB
cord-022561-rv5j1201	1988	16	affect	affect	VBP
cord-022561-rv5j1201	1988	17	the	the	DT
cord-022561-rv5j1201	1988	18	levels	level	NNS
cord-022561-rv5j1201	1988	19	of	of	IN
cord-022561-rv5j1201	1988	20	B	b	NN
cord-022561-rv5j1201	1988	21	and	and	CC
cord-022561-rv5j1201	1988	22	T	t	NN
cord-022561-rv5j1201	1988	23	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	1988	24	,	,	,
cord-022561-rv5j1201	1988	25	NK	NK	NNP
cord-022561-rv5j1201	1988	26	cells	cell	NNS
cord-022561-rv5j1201	1988	27	,	,	,
cord-022561-rv5j1201	1988	28	and	and	CC
cord-022561-rv5j1201	1988	29	inflammatory	inflammatory	JJ
cord-022561-rv5j1201	1988	30	cytokines	cytokine	NNS
cord-022561-rv5j1201	1988	31	.	.	.
cord-022561-rv5j1201	1989	1	Other	other	JJ
cord-022561-rv5j1201	1989	2	metals	metal	NNS
cord-022561-rv5j1201	1989	3	,	,	,
cord-022561-rv5j1201	1989	4	such	such	JJ
cord-022561-rv5j1201	1989	5	as	as	IN
cord-022561-rv5j1201	1989	6	selenium	selenium	NN
cord-022561-rv5j1201	1989	7	,	,	,
cord-022561-rv5j1201	1989	8	zinc	zinc	NN
cord-022561-rv5j1201	1989	9	,	,	,
cord-022561-rv5j1201	1989	10	and	and	CC
cord-022561-rv5j1201	1989	11	vanadium	vanadium	NN
cord-022561-rv5j1201	1989	12	,	,	,
cord-022561-rv5j1201	1989	13	may	may	MD
cord-022561-rv5j1201	1989	14	be	be	VB
cord-022561-rv5j1201	1989	15	immunostimulatory	immunostimulatory	NN
cord-022561-rv5j1201	1989	16	at	at	IN
cord-022561-rv5j1201	1989	17	low	low	JJ
cord-022561-rv5j1201	1989	18	doses	dose	NNS
cord-022561-rv5j1201	1989	19	.	.	.
cord-022561-rv5j1201	1990	1	The	the	DT
cord-022561-rv5j1201	1990	2	immunotoxic	immunotoxic	JJ
cord-022561-rv5j1201	1990	3	mechanisms	mechanism	NNS
cord-022561-rv5j1201	1990	4	may	may	MD
cord-022561-rv5j1201	1990	5	differ	differ	VB
cord-022561-rv5j1201	1990	6	and	and	CC
cord-022561-rv5j1201	1990	7	include	include	VBP
cord-022561-rv5j1201	1990	8	chelation	chelation	NN
cord-022561-rv5j1201	1990	9	of	of	IN
cord-022561-rv5j1201	1990	10	molecules	molecule	NNS
cord-022561-rv5j1201	1990	11	and	and	CC
cord-022561-rv5j1201	1990	12	effects	effect	NNS
cord-022561-rv5j1201	1990	13	on	on	IN
cord-022561-rv5j1201	1990	14	protein	protein	NN
cord-022561-rv5j1201	1990	15	synthesis	synthesis	NN
cord-022561-rv5j1201	1990	16	,	,	,
cord-022561-rv5j1201	1990	17	cell	cell	NN
cord-022561-rv5j1201	1990	18	membrane	membrane	NN
cord-022561-rv5j1201	1990	19	integrity	integrity	NN
cord-022561-rv5j1201	1990	20	,	,	,
cord-022561-rv5j1201	1990	21	and	and	CC
cord-022561-rv5j1201	1990	22	nucleic	nucleic	JJ
cord-022561-rv5j1201	1990	23	acid	acid	NN
cord-022561-rv5j1201	1990	24	replication	replication	NN
cord-022561-rv5j1201	1990	25	.	.	.
cord-022561-rv5j1201	1991	1	The	the	DT
cord-022561-rv5j1201	1991	2	toxic	toxic	JJ
cord-022561-rv5j1201	1991	3	effects	effect	NNS
cord-022561-rv5j1201	1991	4	of	of	IN
cord-022561-rv5j1201	1991	5	mycotoxins	mycotoxin	NNS
cord-022561-rv5j1201	1991	6	such	such	JJ
cord-022561-rv5j1201	1991	7	as	as	IN
cord-022561-rv5j1201	1991	8	fumonisins	fumonisins	NNP
cord-022561-rv5j1201	1991	9	B	B	NNP
cord-022561-rv5j1201	1991	10	1	1	CD
cord-022561-rv5j1201	1991	11	and	and	CC
cord-022561-rv5j1201	1991	12	B	b	NN
cord-022561-rv5j1201	1991	13	2	2	CD
cord-022561-rv5j1201	1991	14	(	(	-LRB-
cord-022561-rv5j1201	1991	15	secondary	secondary	JJ
cord-022561-rv5j1201	1991	16	fungal	fungal	JJ
cord-022561-rv5j1201	1991	17	metabolites	metabolite	NNS
cord-022561-rv5j1201	1991	18	produced	produce	VBN
cord-022561-rv5j1201	1991	19	by	by	IN
cord-022561-rv5j1201	1991	20	members	member	NNS
cord-022561-rv5j1201	1991	21	of	of	IN
cord-022561-rv5j1201	1991	22	the	the	DT
cord-022561-rv5j1201	1991	23	genus	genus	NN
cord-022561-rv5j1201	1991	24	Fusarium	fusarium	NN
cord-022561-rv5j1201	1991	25	)	)	-RRB-
cord-022561-rv5j1201	1991	26	and	and	CC
cord-022561-rv5j1201	1991	27	aflatoxin	aflatoxin	NN
cord-022561-rv5j1201	1991	28	(	(	-LRB-
cord-022561-rv5j1201	1991	29	produced	produce	VBN
cord-022561-rv5j1201	1991	30	by	by	IN
cord-022561-rv5j1201	1991	31	Aspergillus	aspergillus	NN
cord-022561-rv5j1201	1991	32	flavus	flavu	NNS
cord-022561-rv5j1201	1991	33	)	)	-RRB-
cord-022561-rv5j1201	1991	34	include	include	VBP
cord-022561-rv5j1201	1991	35	lymphocytolysis	lymphocytolysis	NNP
cord-022561-rv5j1201	1991	36	in	in	IN
cord-022561-rv5j1201	1991	37	the	the	DT
cord-022561-rv5j1201	1991	38	thymic	thymic	JJ
cord-022561-rv5j1201	1991	39	cortex	cortex	NN
cord-022561-rv5j1201	1991	40	.	.	.
cord-022561-rv5j1201	1992	1	Box	Box	NNP
cord-022561-rv5j1201	1992	2	13	13	CD
cord-022561-rv5j1201	1992	3	-	-	SYM
cord-022561-rv5j1201	1992	4	10	10	CD
cord-022561-rv5j1201	1992	5	Responses	response	NNS
cord-022561-rv5j1201	1992	6	of	of	IN
cord-022561-rv5j1201	1992	7	Mucosa	Mucosa	NNP
cord-022561-rv5j1201	1992	8	-	-	HYPH
cord-022561-rv5j1201	1992	9	Associated	Associated	NNP
cord-022561-rv5j1201	1992	10	Lymphoid	Lymphoid	NNP
cord-022561-rv5j1201	1992	11	Tissue	Tissue	NNP
cord-022561-rv5j1201	1992	12	to	to	IN
cord-022561-rv5j1201	1992	13	Injury	injury	NN
cord-022561-rv5j1201	1992	14	described	describe	VBN
cord-022561-rv5j1201	1992	15	in	in	IN
cord-022561-rv5j1201	1992	16	the	the	DT
cord-022561-rv5j1201	1992	17	sections	section	NNS
cord-022561-rv5j1201	1992	18	on	on	IN
cord-022561-rv5j1201	1992	19	Disorders	disorder	NNS
cord-022561-rv5j1201	1992	20	of	of	IN
cord-022561-rv5j1201	1992	21	Horses	horse	NNS
cord-022561-rv5j1201	1992	22	and	and	CC
cord-022561-rv5j1201	1992	23	Disorders	disorder	NNS
cord-022561-rv5j1201	1992	24	of	of	IN
cord-022561-rv5j1201	1992	25	Dogs	dog	NNS
cord-022561-rv5j1201	1992	26	.	.	.
cord-022561-rv5j1201	1993	1	Thymic	Thymic	NNP
cord-022561-rv5j1201	1993	2	cysts	cyst	NNS
cord-022561-rv5j1201	1993	3	can	can	MD
cord-022561-rv5j1201	1993	4	be	be	VB
cord-022561-rv5j1201	1993	5	found	find	VBN
cord-022561-rv5j1201	1993	6	within	within	IN
cord-022561-rv5j1201	1993	7	the	the	DT
cord-022561-rv5j1201	1993	8	developing	develop	VBG
cord-022561-rv5j1201	1993	9	and	and	CC
cord-022561-rv5j1201	1993	10	mature	mature	VB
cord-022561-rv5j1201	1993	11	thymus	thymus	NN
cord-022561-rv5j1201	1993	12	and	and	CC
cord-022561-rv5j1201	1993	13	in	in	IN
cord-022561-rv5j1201	1993	14	thymic	thymic	JJ
cord-022561-rv5j1201	1993	15	remnants	remnant	NNS
cord-022561-rv5j1201	1993	16	in	in	IN
cord-022561-rv5j1201	1993	17	the	the	DT
cord-022561-rv5j1201	1993	18	cranial	cranial	JJ
cord-022561-rv5j1201	1993	19	mediastinum	mediastinum	NN
cord-022561-rv5j1201	1993	20	.	.	.
cord-022561-rv5j1201	1994	1	Thymic	Thymic	NNP
cord-022561-rv5j1201	1994	2	cysts	cyst	NNS
cord-022561-rv5j1201	1994	3	are	be	VBP
cord-022561-rv5j1201	1994	4	often	often	RB
cord-022561-rv5j1201	1994	5	lined	line	VBN
cord-022561-rv5j1201	1994	6	by	by	IN
cord-022561-rv5j1201	1994	7	ciliated	ciliated	JJ
cord-022561-rv5j1201	1994	8	epithelium	epithelium	NN
cord-022561-rv5j1201	1994	9	and	and	CC
cord-022561-rv5j1201	1994	10	represent	represent	VB
cord-022561-rv5j1201	1994	11	developmental	developmental	JJ
cord-022561-rv5j1201	1994	12	remnants	remnant	NNS
cord-022561-rv5j1201	1994	13	of	of	IN
cord-022561-rv5j1201	1994	14	branchial	branchial	JJ
cord-022561-rv5j1201	1994	15	arch	arch	JJ
cord-022561-rv5j1201	1994	16	epithelium	epithelium	NN
cord-022561-rv5j1201	1994	17	and	and	CC
cord-022561-rv5j1201	1994	18	are	be	VBP
cord-022561-rv5j1201	1994	19	usually	usually	RB
cord-022561-rv5j1201	1994	20	of	of	IN
cord-022561-rv5j1201	1994	21	no	no	DT
cord-022561-rv5j1201	1994	22	significance	significance	NN
cord-022561-rv5j1201	1994	23	.	.	.
cord-022561-rv5j1201	1995	1	Thymitis	Thymitis	NNP
cord-022561-rv5j1201	1995	2	is	be	VBZ
cord-022561-rv5j1201	1995	3	an	an	DT
cord-022561-rv5j1201	1995	4	uncommon	uncommon	JJ
cord-022561-rv5j1201	1995	5	lesion	lesion	NN
cord-022561-rv5j1201	1995	6	and	and	CC
cord-022561-rv5j1201	1995	7	may	may	MD
cord-022561-rv5j1201	1995	8	be	be	VB
cord-022561-rv5j1201	1995	9	seen	see	VBN
cord-022561-rv5j1201	1995	10	in	in	IN
cord-022561-rv5j1201	1995	11	PCV2	pcv2	JJ
cord-022561-rv5j1201	1995	12	infection	infection	NN
cord-022561-rv5j1201	1995	13	(	(	-LRB-
cord-022561-rv5j1201	1995	14	see	see	VB
cord-022561-rv5j1201	1995	15	Disorders	disorder	NNS
cord-022561-rv5j1201	1995	16	of	of	IN
cord-022561-rv5j1201	1995	17	Pigs	Pigs	NNPS
cord-022561-rv5j1201	1995	18	and	and	CC
cord-022561-rv5j1201	1995	19	also	also	RB
cord-022561-rv5j1201	1995	20	Chapter	chapter	NN
cord-022561-rv5j1201	1995	21	4	4	CD
cord-022561-rv5j1201	1995	22	)	)	-RRB-
cord-022561-rv5j1201	1995	23	,	,	,
cord-022561-rv5j1201	1995	24	enzootic	enzootic	JJ
cord-022561-rv5j1201	1995	25	bovine	bovine	JJ
cord-022561-rv5j1201	1995	26	abortion	abortion	NN
cord-022561-rv5j1201	1995	27	(	(	-LRB-
cord-022561-rv5j1201	1995	28	see	see	VB
cord-022561-rv5j1201	1995	29	Chapter	chapter	NN
cord-022561-rv5j1201	1995	30	18	18	CD
cord-022561-rv5j1201	1995	31	)	)	-RRB-
cord-022561-rv5j1201	1995	32	,	,	,
cord-022561-rv5j1201	1995	33	and	and	CC
cord-022561-rv5j1201	1995	34	salmon	salmon	NN
cord-022561-rv5j1201	1995	35	poisoning	poisoning	NN
cord-022561-rv5j1201	1995	36	disease	disease	NN
cord-022561-rv5j1201	1995	37	of	of	IN
cord-022561-rv5j1201	1995	38	dogs	dog	NNS
cord-022561-rv5j1201	1995	39	(	(	-LRB-
cord-022561-rv5j1201	1995	40	see	see	VB
cord-022561-rv5j1201	1995	41	Chapter	Chapter	NNP
cord-022561-rv5j1201	1995	42	7	7	CD
cord-022561-rv5j1201	1995	43	)	)	-RRB-
cord-022561-rv5j1201	1995	44	.	.	.
cord-022561-rv5j1201	1996	1	Infectious	infectious	JJ
cord-022561-rv5j1201	1996	2	agents	agent	NNS
cord-022561-rv5j1201	1996	3	more	more	RBR
cord-022561-rv5j1201	1996	4	commonly	commonly	RB
cord-022561-rv5j1201	1996	5	cause	cause	VBP
cord-022561-rv5j1201	1996	6	thymic	thymic	JJ
cord-022561-rv5j1201	1996	7	atrophy	atrophy	NN
cord-022561-rv5j1201	1996	8	.	.	.
cord-022561-rv5j1201	1997	1	Variable	variable	JJ
cord-022561-rv5j1201	1997	2	degrees	degree	NNS
cord-022561-rv5j1201	1997	3	of	of	IN
cord-022561-rv5j1201	1997	4	acquired	acquire	VBN
cord-022561-rv5j1201	1997	5	immunodeficiency	immunodeficiency	NN
cord-022561-rv5j1201	1997	6	can	can	MD
cord-022561-rv5j1201	1997	7	be	be	VB
cord-022561-rv5j1201	1997	8	also	also	RB
cord-022561-rv5j1201	1997	9	be	be	VB
cord-022561-rv5j1201	1997	10	caused	cause	VBN
cord-022561-rv5j1201	1997	11	by	by	IN
cord-022561-rv5j1201	1997	12	toxins	toxin	NNS
cord-022561-rv5j1201	1997	13	,	,	,
cord-022561-rv5j1201	1997	14	chemotherapeutic	chemotherapeutic	JJ
cord-022561-rv5j1201	1997	15	agents	agent	NNS
cord-022561-rv5j1201	1997	16	and	and	CC
cord-022561-rv5j1201	1997	17	radiation	radiation	NN
cord-022561-rv5j1201	1997	18	,	,	,
cord-022561-rv5j1201	1997	19	malnutrition	malnutrition	NN
cord-022561-rv5j1201	1997	20	,	,	,
cord-022561-rv5j1201	1997	21	aging	age	VBG
cord-022561-rv5j1201	1997	22	,	,	,
cord-022561-rv5j1201	1997	23	and	and	CC
cord-022561-rv5j1201	1997	24	neoplasia	neoplasia	NN
cord-022561-rv5j1201	1997	25	.	.	.
cord-022561-rv5j1201	1998	1	Of	of	IN
cord-022561-rv5j1201	1998	2	infectious	infectious	JJ
cord-022561-rv5j1201	1998	3	agents	agent	NNS
cord-022561-rv5j1201	1998	4	,	,	,
cord-022561-rv5j1201	1998	5	viruses	virus	NNS
cord-022561-rv5j1201	1998	6	most	most	RBS
cord-022561-rv5j1201	1998	7	commonly	commonly	RB
cord-022561-rv5j1201	1998	8	infect	infect	VBP
cord-022561-rv5j1201	1998	9	and	and	CC
cord-022561-rv5j1201	1998	10	injure	injure	VB
cord-022561-rv5j1201	1998	11	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	1998	12	tissues	tissue	NNS
cord-022561-rv5j1201	1998	13	and	and	CC
cord-022561-rv5j1201	1998	14	include	include	VBP
cord-022561-rv5j1201	1998	15	the	the	DT
cord-022561-rv5j1201	1998	16	following	follow	VBG
cord-022561-rv5j1201	1998	17	:	:	:
cord-022561-rv5j1201	1998	18	EHV-1	EHV-1	NNPS
cord-022561-rv5j1201	1998	19	in	in	IN
cord-022561-rv5j1201	1998	20	aborted	abort	VBN
cord-022561-rv5j1201	1998	21	foals	foal	NNS
cord-022561-rv5j1201	1999	1	(	(	-LRB-
cord-022561-rv5j1201	1999	2	Fig	Fig	NNP
cord-022561-rv5j1201	1999	3	.	.	NNP
cord-022561-rv5j1201	1999	4	13	13	CD
cord-022561-rv5j1201	1999	5	-	-	SYM
cord-022561-rv5j1201	1999	6	52	52	CD
cord-022561-rv5j1201	1999	7	)	)	-RRB-
cord-022561-rv5j1201	1999	8	,	,	,
cord-022561-rv5j1201	1999	9	classic	classic	JJ
cord-022561-rv5j1201	1999	10	swine	swine	NN
cord-022561-rv5j1201	1999	11	fever	fever	NN
cord-022561-rv5j1201	1999	12	virus	virus	NN
cord-022561-rv5j1201	1999	13	,	,	,
cord-022561-rv5j1201	1999	14	BVDV	BVDV	NNP
cord-022561-rv5j1201	1999	15	,	,	,
cord-022561-rv5j1201	1999	16	canine	canine	JJ
cord-022561-rv5j1201	1999	17	distemper	distemper	NN
cord-022561-rv5j1201	1999	18	virus	virus	NN
cord-022561-rv5j1201	1999	19	,	,	,
cord-022561-rv5j1201	1999	20	canine	canine	JJ
cord-022561-rv5j1201	1999	21	and	and	CC
cord-022561-rv5j1201	1999	22	feline	feline	JJ
cord-022561-rv5j1201	1999	23	parvovirus	parvovirus	NN
cord-022561-rv5j1201	1999	24	,	,	,
cord-022561-rv5j1201	1999	25	and	and	CC
cord-022561-rv5j1201	1999	26	FIV	fiv	NN
cord-022561-rv5j1201	1999	27	;	;	,
cord-022561-rv5j1201	1999	28	severe	severe	JJ
cord-022561-rv5j1201	1999	29	thymic	thymic	JJ
cord-022561-rv5j1201	1999	30	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	1999	31	depletion	depletion	NN
cord-022561-rv5j1201	1999	32	is	be	VBZ
cord-022561-rv5j1201	1999	33	an	an	DT
cord-022561-rv5j1201	1999	34	early	early	JJ
cord-022561-rv5j1201	1999	35	lesion	lesion	NN
cord-022561-rv5j1201	1999	36	in	in	IN
cord-022561-rv5j1201	1999	37	FIV	fiv	NN
cord-022561-rv5j1201	1999	38	-	-	HYPH
cord-022561-rv5j1201	1999	39	infected	infect	VBN
cord-022561-rv5j1201	1999	40	kittens	kitten	NNS
cord-022561-rv5j1201	1999	41	.	.	.
cord-022561-rv5j1201	2000	1	Environmental	environmental	JJ
cord-022561-rv5j1201	2000	2	toxins	toxin	NNS
cord-022561-rv5j1201	2000	3	,	,	,
cord-022561-rv5j1201	2000	4	such	such	JJ
cord-022561-rv5j1201	2000	5	as	as	IN
cord-022561-rv5j1201	2000	6	halogenated	halogenated	JJ
cord-022561-rv5j1201	2000	7	aromatic	aromatic	JJ
cord-022561-rv5j1201	2000	8	hydrocarbons	hydrocarbon	NNS
cord-022561-rv5j1201	2000	9	(	(	-LRB-
cord-022561-rv5j1201	2000	10	e.g.	e.g.	RB
cord-022561-rv5j1201	2000	11	,	,	,
cord-022561-rv5j1201	2000	12	polychlorinated	polychlorinated	JJ
cord-022561-rv5j1201	2000	13	biphenyls	biphenyl	NNS
cord-022561-rv5j1201	2000	14	and	and	CC
cord-022561-rv5j1201	2000	15	dibenzodioxins	dibenzodioxins	NNP
cord-022561-rv5j1201	2000	16	)	)	-RRB-
cord-022561-rv5j1201	2000	17	,	,	,
cord-022561-rv5j1201	2000	18	lead	lead	NN
cord-022561-rv5j1201	2000	19	,	,	,
cord-022561-rv5j1201	2000	20	and	and	CC
cord-022561-rv5j1201	2000	21	Thymic	Thymic	NNP
cord-022561-rv5j1201	2000	22	Hyperplasia	Hyperplasia	NNP
cord-022561-rv5j1201	2000	23	.	.	.
cord-022561-rv5j1201	2001	1	Asymptomatic	asymptomatic	JJ
cord-022561-rv5j1201	2001	2	hyperplasia	hyperplasia	NN
cord-022561-rv5j1201	2001	3	may	may	MD
cord-022561-rv5j1201	2001	4	occur	occur	VB
cord-022561-rv5j1201	2001	5	in	in	IN
cord-022561-rv5j1201	2001	6	juvenile	juvenile	JJ
cord-022561-rv5j1201	2001	7	animals	animal	NNS
cord-022561-rv5j1201	2001	8	in	in	IN
cord-022561-rv5j1201	2001	9	association	association	NN
cord-022561-rv5j1201	2001	10	with	with	IN
cord-022561-rv5j1201	2001	11	immunizations	immunization	NNS
cord-022561-rv5j1201	2001	12	and	and	CC
cord-022561-rv5j1201	2001	13	results	result	NNS
cord-022561-rv5j1201	2001	14	in	in	IN
cord-022561-rv5j1201	2001	15	symmetrical	symmetrical	JJ
cord-022561-rv5j1201	2001	16	increase	increase	NN
cord-022561-rv5j1201	2001	17	in	in	IN
cord-022561-rv5j1201	2001	18	the	the	DT
cord-022561-rv5j1201	2001	19	size	size	NN
cord-022561-rv5j1201	2001	20	of	of	IN
cord-022561-rv5j1201	2001	21	the	the	DT
cord-022561-rv5j1201	2001	22	thymus	thymus	NN
cord-022561-rv5j1201	2001	23	.	.	.
cord-022561-rv5j1201	2002	1	Autoimmune	autoimmune	JJ
cord-022561-rv5j1201	2002	2	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	2002	3	hyperplasia	hyperplasia	NN
cord-022561-rv5j1201	2002	4	of	of	IN
cord-022561-rv5j1201	2002	5	the	the	DT
cord-022561-rv5j1201	2002	6	thymus	thymus	NN
cord-022561-rv5j1201	2002	7	has	have	VBZ
cord-022561-rv5j1201	2002	8	germinal	germinal	JJ
cord-022561-rv5j1201	2002	9	center	center	NN
cord-022561-rv5j1201	2002	10	formation	formation	NN
cord-022561-rv5j1201	2002	11	and	and	CC
cord-022561-rv5j1201	2002	12	occurs	occur	VBZ
cord-022561-rv5j1201	2002	13	with	with	IN
cord-022561-rv5j1201	2002	14	myasthenia	myasthenia	NN
cord-022561-rv5j1201	2002	15	gravis	gravis	NN
cord-022561-rv5j1201	2002	16	.	.	.
cord-022561-rv5j1201	2003	1	Asplenia	asplenia	NN
cord-022561-rv5j1201	2003	2	or	or	CC
cord-022561-rv5j1201	2003	3	the	the	DT
cord-022561-rv5j1201	2003	4	failure	failure	NN
cord-022561-rv5j1201	2003	5	of	of	IN
cord-022561-rv5j1201	2003	6	a	a	DT
cord-022561-rv5j1201	2003	7	spleen	spleen	NN
cord-022561-rv5j1201	2003	8	to	to	TO
cord-022561-rv5j1201	2003	9	develop	develop	VB
cord-022561-rv5j1201	2003	10	in	in	IN
cord-022561-rv5j1201	2003	11	utero	utero	NN
cord-022561-rv5j1201	2003	12	occurs	occur	VBZ
cord-022561-rv5j1201	2003	13	rarely	rarely	RB
cord-022561-rv5j1201	2003	14	in	in	IN
cord-022561-rv5j1201	2003	15	animals	animal	NNS
cord-022561-rv5j1201	2003	16	,	,	,
cord-022561-rv5j1201	2003	17	and	and	CC
cord-022561-rv5j1201	2003	18	the	the	DT
cord-022561-rv5j1201	2003	19	effect	effect	NN
cord-022561-rv5j1201	2003	20	on	on	IN
cord-022561-rv5j1201	2003	21	the	the	DT
cord-022561-rv5j1201	2003	22	animal	animal	NN
cord-022561-rv5j1201	2003	23	's	's	POS
cord-022561-rv5j1201	2003	24	immune	immune	JJ
cord-022561-rv5j1201	2003	25	status	status	NN
cord-022561-rv5j1201	2003	26	is	be	VBZ
cord-022561-rv5j1201	2003	27	uncertain	uncertain	JJ
cord-022561-rv5j1201	2003	28	.	.	.
cord-022561-rv5j1201	2004	1	(	(	-LRB-
cord-022561-rv5j1201	2004	2	Splenic	Splenic	NNP
cord-022561-rv5j1201	2004	3	aplasia	aplasia	NNP
cord-022561-rv5j1201	2004	4	is	be	VBZ
cord-022561-rv5j1201	2004	5	present	present	JJ
cord-022561-rv5j1201	2004	6	in	in	IN
cord-022561-rv5j1201	2004	7	certain	certain	JJ
cord-022561-rv5j1201	2004	8	strains	strain	NNS
cord-022561-rv5j1201	2004	9	of	of	IN
cord-022561-rv5j1201	2004	10	mice	mouse	NNS
cord-022561-rv5j1201	2004	11	,	,	,
cord-022561-rv5j1201	2004	12	but	but	CC
cord-022561-rv5j1201	2004	13	because	because	IN
cord-022561-rv5j1201	2004	14	these	these	DT
cord-022561-rv5j1201	2004	15	are	be	VBP
cord-022561-rv5j1201	2004	16	usually	usually	RB
cord-022561-rv5j1201	2004	17	maintained	maintain	VBN
cord-022561-rv5j1201	2004	18	under	under	IN
cord-022561-rv5j1201	2004	19	either	either	DT
cord-022561-rv5j1201	2004	20	germ	germ	NN
cord-022561-rv5j1201	2004	21	-	-	HYPH
cord-022561-rv5j1201	2004	22	free	free	JJ
cord-022561-rv5j1201	2004	23	or	or	CC
cord-022561-rv5j1201	2004	24	specific	specific	JJ
cord-022561-rv5j1201	2004	25	pathogen	pathogen	NN
cord-022561-rv5j1201	2004	26	-	-	HYPH
cord-022561-rv5j1201	2004	27	free	free	JJ
cord-022561-rv5j1201	2004	28	[	[	-LRB-
cord-022561-rv5j1201	2004	29	SPF	SPF	NNP
cord-022561-rv5j1201	2004	30	]	]	-RRB-
cord-022561-rv5j1201	2004	31	conditions	condition	NNS
cord-022561-rv5j1201	2004	32	,	,	,
cord-022561-rv5j1201	2004	33	the	the	DT
cord-022561-rv5j1201	2004	34	effect	effect	NN
cord-022561-rv5j1201	2004	35	of	of	IN
cord-022561-rv5j1201	2004	36	asplenia	asplenia	NN
cord-022561-rv5j1201	2004	37	can	can	MD
cord-022561-rv5j1201	2004	38	not	not	RB
cord-022561-rv5j1201	2004	39	be	be	VB
cord-022561-rv5j1201	2004	40	evaluated	evaluate	VBN
cord-022561-rv5j1201	2004	41	.	.	.
cord-022561-rv5j1201	2004	42	)	)	-RRB-
cord-022561-rv5j1201	2005	1	Congenital	congenital	JJ
cord-022561-rv5j1201	2005	2	immunodeficiency	immunodeficiency	NN
cord-022561-rv5j1201	2005	3	diseases	disease	NNS
cord-022561-rv5j1201	2005	4	are	be	VBP
cord-022561-rv5j1201	2005	5	described	describe	VBN
cord-022561-rv5j1201	2005	6	in	in	IN
cord-022561-rv5j1201	2005	7	detail	detail	NN
cord-022561-rv5j1201	2005	8	in	in	IN
cord-022561-rv5j1201	2005	9	Chapter	chapter	NN
cord-022561-rv5j1201	2005	10	5	5	CD
cord-022561-rv5j1201	2005	11	,	,	,
cord-022561-rv5j1201	2005	12	and	and	CC
cord-022561-rv5j1201	2005	13	in	in	IN
cord-022561-rv5j1201	2005	14	the	the	DT
cord-022561-rv5j1201	2005	15	sections	section	NNS
cord-022561-rv5j1201	2005	16	on	on	IN
cord-022561-rv5j1201	2005	17	Disorders	disorder	NNS
cord-022561-rv5j1201	2005	18	of	of	IN
cord-022561-rv5j1201	2005	19	Horses	horse	NNS
cord-022561-rv5j1201	2005	20	and	and	CC
cord-022561-rv5j1201	2005	21	Disorders	disorder	NNS
cord-022561-rv5j1201	2005	22	of	of	IN
cord-022561-rv5j1201	2005	23	Dogs	dog	NNS
cord-022561-rv5j1201	2005	24	.	.	.
cord-022561-rv5j1201	2006	1	Gross	gross	JJ
cord-022561-rv5j1201	2006	2	examination	examination	NN
cord-022561-rv5j1201	2006	3	of	of	IN
cord-022561-rv5j1201	2006	4	the	the	DT
cord-022561-rv5j1201	2006	5	spleen	spleen	NN
cord-022561-rv5j1201	2006	6	involves	involve	VBZ
cord-022561-rv5j1201	2006	7	deciding	decide	VBG
cord-022561-rv5j1201	2006	8	whether	whether	IN
cord-022561-rv5j1201	2006	9	the	the	DT
cord-022561-rv5j1201	2006	10	spleen	spleen	NN
cord-022561-rv5j1201	2006	11	is	be	VBZ
cord-022561-rv5j1201	2006	12	enlarged	enlarge	VBN
cord-022561-rv5j1201	2006	13	(	(	-LRB-
cord-022561-rv5j1201	2006	14	splenomegaly	splenomegaly	NN
cord-022561-rv5j1201	2006	15	)	)	-RRB-
cord-022561-rv5j1201	2006	16	,	,	,
cord-022561-rv5j1201	2006	17	normal	normal	JJ
cord-022561-rv5j1201	2006	18	,	,	,
cord-022561-rv5j1201	2006	19	or	or	CC
cord-022561-rv5j1201	2006	20	small	small	JJ
cord-022561-rv5j1201	2006	21	(	(	-LRB-
cord-022561-rv5j1201	2006	22	see	see	VB
cord-022561-rv5j1201	2006	23	E	E	NNP
cord-022561-rv5j1201	2006	24	-	-	NNP
cord-022561-rv5j1201	2006	25	Appendix	Appendix	NNP
cord-022561-rv5j1201	2006	26	13	13	CD
cord-022561-rv5j1201	2006	27	-	-	SYM
cord-022561-rv5j1201	2006	28	2	2	CD
cord-022561-rv5j1201	2006	29	)	)	-RRB-
cord-022561-rv5j1201	2006	30	.	.	.
cord-022561-rv5j1201	2007	1	Diffuse	diffuse	JJ
cord-022561-rv5j1201	2007	2	enlargement	enlargement	NN
cord-022561-rv5j1201	2007	3	of	of	IN
cord-022561-rv5j1201	2007	4	the	the	DT
cord-022561-rv5j1201	2007	5	spleen	spleen	NN
cord-022561-rv5j1201	2007	6	may	may	MD
cord-022561-rv5j1201	2007	7	be	be	VB
cord-022561-rv5j1201	2007	8	due	due	JJ
cord-022561-rv5j1201	2007	9	to	to	IN
cord-022561-rv5j1201	2007	10	congestion	congestion	NN
cord-022561-rv5j1201	2007	11	(	(	-LRB-
cord-022561-rv5j1201	2007	12	termed	term	VBN
cord-022561-rv5j1201	2007	13	bloody	bloody	JJ
cord-022561-rv5j1201	2007	14	spleen	spleen	NN
cord-022561-rv5j1201	2007	15	)	)	-RRB-
cord-022561-rv5j1201	2007	16	or	or	CC
cord-022561-rv5j1201	2007	17	other	other	JJ
cord-022561-rv5j1201	2007	18	infiltrative	infiltrative	JJ
cord-022561-rv5j1201	2007	19	disease	disease	NN
cord-022561-rv5j1201	2007	20	(	(	-LRB-
cord-022561-rv5j1201	2007	21	termed	term	VBN
cord-022561-rv5j1201	2007	22	meaty	meaty	JJ
cord-022561-rv5j1201	2007	23	spleen	spleen	NNS
cord-022561-rv5j1201	2007	24	)	)	-RRB-
cord-022561-rv5j1201	2007	25	.	.	.
cord-022561-rv5j1201	2008	1	The	the	DT
cord-022561-rv5j1201	2008	2	cut	cut	NN
cord-022561-rv5j1201	2008	3	surface	surface	NN
cord-022561-rv5j1201	2008	4	of	of	IN
cord-022561-rv5j1201	2008	5	congested	congested	JJ
cord-022561-rv5j1201	2008	6	spleens	spleen	NNS
cord-022561-rv5j1201	2008	7	will	will	MD
cord-022561-rv5j1201	2008	8	exude	exude	VB
cord-022561-rv5j1201	2008	9	blood	blood	NN
cord-022561-rv5j1201	2008	10	,	,	,
cord-022561-rv5j1201	2008	11	whereas	whereas	IN
cord-022561-rv5j1201	2008	12	meaty	meaty	JJ
cord-022561-rv5j1201	2008	13	spleens	spleen	NNS
cord-022561-rv5j1201	2008	14	are	be	VBP
cord-022561-rv5j1201	2008	15	more	more	RBR
cord-022561-rv5j1201	2008	16	firm	firm	JJ
cord-022561-rv5j1201	2008	17	and	and	CC
cord-022561-rv5j1201	2008	18	do	do	VBP
cord-022561-rv5j1201	2008	19	not	not	RB
cord-022561-rv5j1201	2008	20	readily	readily	RB
cord-022561-rv5j1201	2008	21	ooze	ooze	VB
cord-022561-rv5j1201	2008	22	blood	blood	NN
cord-022561-rv5j1201	2008	23	.	.	.
cord-022561-rv5j1201	2009	1	The	the	DT
cord-022561-rv5j1201	2009	2	diseases	disease	NNS
cord-022561-rv5j1201	2009	3	and	and	CC
cord-022561-rv5j1201	2009	4	disorders	disorder	NNS
cord-022561-rv5j1201	2009	5	having	have	VBG
cord-022561-rv5j1201	2009	6	splenomegaly	splenomegaly	NNS
cord-022561-rv5j1201	2009	7	are	be	VBP
cord-022561-rv5j1201	2009	8	discussed	discuss	VBN
cord-022561-rv5j1201	2009	9	using	use	VBG
cord-022561-rv5j1201	2009	10	the	the	DT
cord-022561-rv5j1201	2009	11	following	follow	VBG
cord-022561-rv5j1201	2009	12	categories	category	NNS
cord-022561-rv5j1201	2009	13	,	,	,
cord-022561-rv5j1201	2009	14	which	which	WDT
cord-022561-rv5j1201	2009	15	list	list	VBP
cord-022561-rv5j1201	2009	16	the	the	DT
cord-022561-rv5j1201	2009	17	common	common	JJ
cord-022561-rv5j1201	2009	18	causes	cause	NNS
cord-022561-rv5j1201	2009	19	of	of	IN
cord-022561-rv5j1201	2009	20	uniform	uniform	JJ
cord-022561-rv5j1201	2009	21	splenomegaly	splenomegaly	NN
cord-022561-rv5j1201	2009	22	(	(	-LRB-
cord-022561-rv5j1201	2009	23	Table	Table	NNP
cord-022561-rv5j1201	2009	24	13	13	CD
cord-022561-rv5j1201	2009	25	-	-	SYM
cord-022561-rv5j1201	2009	26	6	6	CD
cord-022561-rv5j1201	2009	27	)	)	-RRB-
cord-022561-rv5j1201	2009	28	:	:	:
cord-022561-rv5j1201	2010	1	•	•	NNP
cord-022561-rv5j1201	2011	1	Uniform	Uniform	NNP
cord-022561-rv5j1201	2011	2	splenomegaly	splenomegaly	NN
cord-022561-rv5j1201	2011	3	with	with	IN
cord-022561-rv5j1201	2011	4	a	a	DT
cord-022561-rv5j1201	2011	5	bloody	bloody	JJ
cord-022561-rv5j1201	2011	6	consistency	consistency	NN
cord-022561-rv5j1201	2011	7	(	(	-LRB-
cord-022561-rv5j1201	2011	8	bloody	bloody	JJ
cord-022561-rv5j1201	2011	9	spleen	spleen	NNS
cord-022561-rv5j1201	2011	10	)	)	-RRB-
cord-022561-rv5j1201	2012	1	(	(	-LRB-
cord-022561-rv5j1201	2012	2	Fig	Fig	NNP
cord-022561-rv5j1201	2012	3	.	.	.
cord-022561-rv5j1201	2012	4	13	13	CD
cord-022561-rv5j1201	2012	5	-	-	SYM
cord-022561-rv5j1201	2012	6	54	54	CD
cord-022561-rv5j1201	2012	7	,	,	,
cord-022561-rv5j1201	2012	8	A	a	NN
cord-022561-rv5j1201	2012	9	)	)	-RRB-
cord-022561-rv5j1201	2012	10	•	•	NNP
cord-022561-rv5j1201	2012	11	Uniform	Uniform	NNP
cord-022561-rv5j1201	2012	12	splenomegaly	splenomegaly	NN
cord-022561-rv5j1201	2012	13	with	with	IN
cord-022561-rv5j1201	2012	14	a	a	DT
cord-022561-rv5j1201	2012	15	firm	firm	JJ
cord-022561-rv5j1201	2012	16	consistency	consistency	NN
cord-022561-rv5j1201	2012	17	(	(	-LRB-
cord-022561-rv5j1201	2012	18	meaty	meaty	JJ
cord-022561-rv5j1201	2012	19	spleen	spleen	NNS
cord-022561-rv5j1201	2012	20	)	)	-RRB-
cord-022561-rv5j1201	2012	21	(	(	-LRB-
cord-022561-rv5j1201	2012	22	see	see	VB
cord-022561-rv5j1201	2012	23	Fig	Fig	NNP
cord-022561-rv5j1201	2012	24	.	.	.
cord-022561-rv5j1201	2013	1	13	13	CD
cord-022561-rv5j1201	2013	2	-	-	SYM
cord-022561-rv5j1201	2013	3	54	54	CD
cord-022561-rv5j1201	2013	4	,	,	,
cord-022561-rv5j1201	2013	5	B	b	NN
cord-022561-rv5j1201	2013	6	)	)	-RRB-
cord-022561-rv5j1201	2013	7	•	•	NN
cord-022561-rv5j1201	2013	8	Splenic	Splenic	NNP
cord-022561-rv5j1201	2013	9	nodules	nodule	NNS
cord-022561-rv5j1201	2013	10	with	with	IN
cord-022561-rv5j1201	2013	11	a	a	DT
cord-022561-rv5j1201	2013	12	bloody	bloody	JJ
cord-022561-rv5j1201	2013	13	consistency	consistency	NN
cord-022561-rv5j1201	2014	1	•	•	NNP
cord-022561-rv5j1201	2015	1	Splenic	Splenic	NNP
cord-022561-rv5j1201	2015	2	nodules	nodule	NNS
cord-022561-rv5j1201	2015	3	with	with	IN
cord-022561-rv5j1201	2015	4	a	a	DT
cord-022561-rv5j1201	2015	5	firm	firm	JJ
cord-022561-rv5j1201	2015	6	consistency	consistency	NN
cord-022561-rv5j1201	2015	7	Uniform	Uniform	NNP
cord-022561-rv5j1201	2015	8	Splenomegaly	Splenomegaly	NNP
cord-022561-rv5j1201	2015	9	with	with	IN
cord-022561-rv5j1201	2015	10	a	a	DT
cord-022561-rv5j1201	2015	11	Bloody	Bloody	NNP
cord-022561-rv5j1201	2015	12	Consistency	Consistency	NNP
cord-022561-rv5j1201	2015	13	-	-	HYPH
cord-022561-rv5j1201	2015	14	Bloody	Bloody	NNP
cord-022561-rv5j1201	2015	15	Spleen	Spleen	NNS
cord-022561-rv5j1201	2015	16	.	.	.
cord-022561-rv5j1201	2016	1	The	the	DT
cord-022561-rv5j1201	2016	2	common	common	JJ
cord-022561-rv5j1201	2016	3	causes	cause	NNS
cord-022561-rv5j1201	2016	4	of	of	IN
cord-022561-rv5j1201	2016	5	a	a	DT
cord-022561-rv5j1201	2016	6	bloody	bloody	JJ
cord-022561-rv5j1201	2016	7	spleen	spleen	NN
cord-022561-rv5j1201	2016	8	are	be	VBP
cord-022561-rv5j1201	2016	9	(	(	-LRB-
cord-022561-rv5j1201	2016	10	1	1	CD
cord-022561-rv5j1201	2016	11	)	)	-RRB-
cord-022561-rv5j1201	2016	12	congestion	congestion	NN
cord-022561-rv5j1201	2016	13	(	(	-LRB-
cord-022561-rv5j1201	2016	14	due	due	IN
cord-022561-rv5j1201	2016	15	to	to	IN
cord-022561-rv5j1201	2016	16	gastric	gastric	JJ
cord-022561-rv5j1201	2016	17	volvulus	volvulus	NN
cord-022561-rv5j1201	2016	18	with	with	IN
cord-022561-rv5j1201	2016	19	splenic	splenic	JJ
cord-022561-rv5j1201	2016	20	entrapment	entrapment	NN
cord-022561-rv5j1201	2016	21	,	,	,
cord-022561-rv5j1201	2016	22	splenic	splenic	JJ
cord-022561-rv5j1201	2016	23	volvulus	volvulus	NN
cord-022561-rv5j1201	2016	24	Chemotherapeutic	chemotherapeutic	JJ
cord-022561-rv5j1201	2016	25	drugs	drug	NNS
cord-022561-rv5j1201	2016	26	inhibit	inhibit	VBP
cord-022561-rv5j1201	2016	27	the	the	DT
cord-022561-rv5j1201	2016	28	cell	cell	NN
cord-022561-rv5j1201	2016	29	cycle	cycle	NN
cord-022561-rv5j1201	2016	30	through	through	IN
cord-022561-rv5j1201	2016	31	various	various	JJ
cord-022561-rv5j1201	2016	32	mechanisms	mechanism	NNS
cord-022561-rv5j1201	2016	33	,	,	,
cord-022561-rv5j1201	2016	34	and	and	CC
cord-022561-rv5j1201	2016	35	thus	thus	RB
cord-022561-rv5j1201	2016	36	all	all	DT
cord-022561-rv5j1201	2016	37	dividing	divide	VBG
cord-022561-rv5j1201	2016	38	cells	cell	NNS
cord-022561-rv5j1201	2016	39	,	,	,
cord-022561-rv5j1201	2016	40	including	include	VBG
cord-022561-rv5j1201	2016	41	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	2016	42	,	,	,
cord-022561-rv5j1201	2016	43	bone	bone	NN
cord-022561-rv5j1201	2016	44	marrow	marrow	NN
cord-022561-rv5j1201	2016	45	cells	cell	NNS
cord-022561-rv5j1201	2016	46	,	,	,
cord-022561-rv5j1201	2016	47	and	and	CC
cord-022561-rv5j1201	2016	48	enterocytes	enterocyte	NNS
cord-022561-rv5j1201	2016	49	,	,	,
cord-022561-rv5j1201	2016	50	are	be	VBP
cord-022561-rv5j1201	2016	51	sensitive	sensitive	JJ
cord-022561-rv5j1201	2016	52	to	to	IN
cord-022561-rv5j1201	2016	53	their	-PRON-	PRP$
cord-022561-rv5j1201	2016	54	effects	effect	NNS
cord-022561-rv5j1201	2016	55	.	.	.
cord-022561-rv5j1201	2017	1	As	as	IN
cord-022561-rv5j1201	2017	2	such	such	JJ
cord-022561-rv5j1201	2017	3	,	,	,
cord-022561-rv5j1201	2017	4	bone	bone	NN
cord-022561-rv5j1201	2017	5	marrow	marrow	NN
cord-022561-rv5j1201	2017	6	suppression	suppression	NN
cord-022561-rv5j1201	2017	7	,	,	,
cord-022561-rv5j1201	2017	8	immunosuppression	immunosuppression	NN
cord-022561-rv5j1201	2017	9	,	,	,
cord-022561-rv5j1201	2017	10	and	and	CC
cord-022561-rv5j1201	2017	11	gastrointestinal	gastrointestinal	JJ
cord-022561-rv5j1201	2017	12	disturbances	disturbance	NNS
cord-022561-rv5j1201	2017	13	are	be	VBP
cord-022561-rv5j1201	2017	14	common	common	JJ
cord-022561-rv5j1201	2017	15	side	side	NN
cord-022561-rv5j1201	2017	16	effects	effect	NNS
cord-022561-rv5j1201	2017	17	of	of	IN
cord-022561-rv5j1201	2017	18	anticancer	anticancer	JJ
cord-022561-rv5j1201	2017	19	drugs	drug	NNS
cord-022561-rv5j1201	2017	20	.	.	.
cord-022561-rv5j1201	2018	1	Purine	Purine	NNP
cord-022561-rv5j1201	2018	2	analogues	analogue	NNS
cord-022561-rv5j1201	2018	3	(	(	-LRB-
cord-022561-rv5j1201	2018	4	e.g.	e.g.	RB
cord-022561-rv5j1201	2018	5	,	,	,
cord-022561-rv5j1201	2018	6	azathioprine	azathioprine	NN
cord-022561-rv5j1201	2018	7	)	)	-RRB-
cord-022561-rv5j1201	2018	8	compete	compete	VBP
cord-022561-rv5j1201	2018	9	with	with	IN
cord-022561-rv5j1201	2018	10	purines	purine	NNS
cord-022561-rv5j1201	2018	11	in	in	IN
cord-022561-rv5j1201	2018	12	the	the	DT
cord-022561-rv5j1201	2018	13	synthesis	synthesis	NN
cord-022561-rv5j1201	2018	14	of	of	IN
cord-022561-rv5j1201	2018	15	nucleic	nucleic	JJ
cord-022561-rv5j1201	2018	16	acids	acid	NNS
cord-022561-rv5j1201	2018	17	,	,	,
cord-022561-rv5j1201	2018	18	whereas	whereas	IN
cord-022561-rv5j1201	2018	19	alkylating	alkylating	JJ
cord-022561-rv5j1201	2018	20	agents	agent	NNS
cord-022561-rv5j1201	2018	21	like	like	IN
cord-022561-rv5j1201	2018	22	cyclophosphamide	cyclophosphamide	NN
cord-022561-rv5j1201	2018	23	cross	cross	JJ
cord-022561-rv5j1201	2018	24	-	-	JJ
cord-022561-rv5j1201	2018	25	link	link	JJ
cord-022561-rv5j1201	2018	26	DNA	dna	NN
cord-022561-rv5j1201	2018	27	and	and	CC
cord-022561-rv5j1201	2018	28	inhibit	inhibit	VB
cord-022561-rv5j1201	2018	29	the	the	DT
cord-022561-rv5j1201	2018	30	replication	replication	NN
cord-022561-rv5j1201	2018	31	and	and	CC
cord-022561-rv5j1201	2018	32	activation	activation	NN
cord-022561-rv5j1201	2018	33	of	of	IN
cord-022561-rv5j1201	2018	34	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	2018	35	.	.	.
cord-022561-rv5j1201	2019	1	Cyclosporin	cyclosporin	VB
cord-022561-rv5j1201	2019	2	A	a	DT
cord-022561-rv5j1201	2019	3	specifically	specifically	RB
cord-022561-rv5j1201	2019	4	inhibits	inhibit	VBZ
cord-022561-rv5j1201	2019	5	the	the	DT
cord-022561-rv5j1201	2019	6	T	T	NNP
cord-022561-rv5j1201	2019	7	lymphocyte	lymphocyte	NN
cord-022561-rv5j1201	2019	8	signaling	signal	VBG
cord-022561-rv5j1201	2019	9	pathway	pathway	NN
cord-022561-rv5j1201	2019	10	by	by	IN
cord-022561-rv5j1201	2019	11	interfering	interfere	VBG
cord-022561-rv5j1201	2019	12	with	with	IN
cord-022561-rv5j1201	2019	13	the	the	DT
cord-022561-rv5j1201	2019	14	transcription	transcription	NN
cord-022561-rv5j1201	2019	15	of	of	IN
cord-022561-rv5j1201	2019	16	the	the	DT
cord-022561-rv5j1201	2019	17	IL-2	IL-2	NNP
cord-022561-rv5j1201	2019	18	gene	gene	NN
cord-022561-rv5j1201	2019	19	.	.	.
cord-022561-rv5j1201	2020	1	Methotrexate	Methotrexate	NNP
cord-022561-rv5j1201	2020	2	,	,	,
cord-022561-rv5j1201	2020	3	a	a	DT
cord-022561-rv5j1201	2020	4	folic	folic	JJ
cord-022561-rv5j1201	2020	5	acid	acid	NN
cord-022561-rv5j1201	2020	6	antagonist	antagonist	NN
cord-022561-rv5j1201	2020	7	,	,	,
cord-022561-rv5j1201	2020	8	blocks	block	VBZ
cord-022561-rv5j1201	2020	9	the	the	DT
cord-022561-rv5j1201	2020	10	synthesis	synthesis	NN
cord-022561-rv5j1201	2020	11	of	of	IN
cord-022561-rv5j1201	2020	12	thymidine	thymidine	NN
cord-022561-rv5j1201	2020	13	and	and	CC
cord-022561-rv5j1201	2020	14	purine	purine	NN
cord-022561-rv5j1201	2020	15	nucleotides	nucleotide	NNS
cord-022561-rv5j1201	2020	16	.	.	.
cord-022561-rv5j1201	2021	1	The	the	DT
cord-022561-rv5j1201	2021	2	immunosuppressive	immunosuppressive	JJ
cord-022561-rv5j1201	2021	3	effects	effect	NNS
cord-022561-rv5j1201	2021	4	of	of	IN
cord-022561-rv5j1201	2021	5	some	some	DT
cord-022561-rv5j1201	2021	6	of	of	IN
cord-022561-rv5j1201	2021	7	these	these	DT
cord-022561-rv5j1201	2021	8	agents	agent	NNS
cord-022561-rv5j1201	2021	9	is	be	VBZ
cord-022561-rv5j1201	2021	10	desirable	desirable	JJ
cord-022561-rv5j1201	2021	11	for	for	IN
cord-022561-rv5j1201	2021	12	the	the	DT
cord-022561-rv5j1201	2021	13	treatment	treatment	NN
cord-022561-rv5j1201	2021	14	of	of	IN
cord-022561-rv5j1201	2021	15	immune	immune	NN
cord-022561-rv5j1201	2021	16	-	-	HYPH
cord-022561-rv5j1201	2021	17	mediated	mediate	VBN
cord-022561-rv5j1201	2021	18	disease	disease	NN
cord-022561-rv5j1201	2021	19	(	(	-LRB-
cord-022561-rv5j1201	2021	20	e.g.	e.g.	RB
cord-022561-rv5j1201	2021	21	,	,	,
cord-022561-rv5j1201	2021	22	immune	immune	NN
cord-022561-rv5j1201	2021	23	-	-	HYPH
cord-022561-rv5j1201	2021	24	mediated	mediate	VBN
cord-022561-rv5j1201	2021	25	hemolytic	hemolytic	JJ
cord-022561-rv5j1201	2021	26	anemia	anemia	NN
cord-022561-rv5j1201	2021	27	)	)	-RRB-
cord-022561-rv5j1201	2021	28	or	or	CC
cord-022561-rv5j1201	2021	29	to	to	TO
cord-022561-rv5j1201	2021	30	prevent	prevent	VB
cord-022561-rv5j1201	2021	31	allograft	allograft	NN
cord-022561-rv5j1201	2021	32	rejection	rejection	NN
cord-022561-rv5j1201	2021	33	after	after	IN
cord-022561-rv5j1201	2021	34	transplantation	transplantation	NN
cord-022561-rv5j1201	2021	35	.	.	.
cord-022561-rv5j1201	2022	1	Corticosteroids	corticosteroid	NNS
cord-022561-rv5j1201	2022	2	may	may	MD
cord-022561-rv5j1201	2022	3	be	be	VB
cord-022561-rv5j1201	2022	4	given	give	VBN
cord-022561-rv5j1201	2022	5	at	at	IN
cord-022561-rv5j1201	2022	6	an	an	DT
cord-022561-rv5j1201	2022	7	immunosuppressive	immunosuppressive	JJ
cord-022561-rv5j1201	2022	8	dose	dose	NN
cord-022561-rv5j1201	2022	9	,	,	,
cord-022561-rv5j1201	2022	10	though	though	IN
cord-022561-rv5j1201	2022	11	the	the	DT
cord-022561-rv5j1201	2022	12	degree	degree	NN
cord-022561-rv5j1201	2022	13	of	of	IN
cord-022561-rv5j1201	2022	14	suppression	suppression	NN
cord-022561-rv5j1201	2022	15	is	be	VBZ
cord-022561-rv5j1201	2022	16	highly	highly	RB
cord-022561-rv5j1201	2022	17	variable	variable	JJ
cord-022561-rv5j1201	2022	18	among	among	IN
cord-022561-rv5j1201	2022	19	species	specie	NNS
cord-022561-rv5j1201	2022	20	.	.	.
cord-022561-rv5j1201	2023	1	Local	local	JJ
cord-022561-rv5j1201	2023	2	or	or	CC
cord-022561-rv5j1201	2023	3	palliative	palliative	JJ
cord-022561-rv5j1201	2023	4	treatment	treatment	NN
cord-022561-rv5j1201	2023	5	of	of	IN
cord-022561-rv5j1201	2023	6	cancer	cancer	NN
cord-022561-rv5j1201	2023	7	may	may	MD
cord-022561-rv5j1201	2023	8	include	include	VB
cord-022561-rv5j1201	2023	9	radiotherapy	radiotherapy	NN
cord-022561-rv5j1201	2023	10	(	(	-LRB-
cord-022561-rv5j1201	2023	11	ionizing	ionize	VBG
cord-022561-rv5j1201	2023	12	radiation	radiation	NN
cord-022561-rv5j1201	2023	13	)	)	-RRB-
cord-022561-rv5j1201	2023	14	to	to	TO
cord-022561-rv5j1201	2023	15	target	target	VB
cord-022561-rv5j1201	2023	16	and	and	CC
cord-022561-rv5j1201	2023	17	damage	damage	VB
cord-022561-rv5j1201	2023	18	the	the	DT
cord-022561-rv5j1201	2023	19	DNA	dna	NN
cord-022561-rv5j1201	2023	20	of	of	IN
cord-022561-rv5j1201	2023	21	the	the	DT
cord-022561-rv5j1201	2023	22	neoplastic	neoplastic	JJ
cord-022561-rv5j1201	2023	23	cells	cell	NNS
cord-022561-rv5j1201	2023	24	.	.	.
cord-022561-rv5j1201	2024	1	Although	although	IN
cord-022561-rv5j1201	2024	2	some	some	DT
cord-022561-rv5j1201	2024	3	immunosuppression	immunosuppression	NN
cord-022561-rv5j1201	2024	4	may	may	MD
cord-022561-rv5j1201	2024	5	be	be	VB
cord-022561-rv5j1201	2024	6	noted	note	VBN
cord-022561-rv5j1201	2024	7	,	,	,
cord-022561-rv5j1201	2024	8	particularly	particularly	RB
cord-022561-rv5j1201	2024	9	if	if	IN
cord-022561-rv5j1201	2024	10	bone	bone	NN
cord-022561-rv5j1201	2024	11	marrow	marrow	NN
cord-022561-rv5j1201	2024	12	or	or	CC
cord-022561-rv5j1201	2024	13	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	2024	14	tissue	tissue	NN
cord-022561-rv5j1201	2024	15	is	be	VBZ
cord-022561-rv5j1201	2024	16	within	within	IN
cord-022561-rv5j1201	2024	17	the	the	DT
cord-022561-rv5j1201	2024	18	therapeutically	therapeutically	RB
cord-022561-rv5j1201	2024	19	irradiated	irradiate	VBN
cord-022561-rv5j1201	2024	20	field	field	NN
cord-022561-rv5j1201	2024	21	,	,	,
cord-022561-rv5j1201	2024	22	mounting	mount	VBG
cord-022561-rv5j1201	2024	23	evidence	evidence	NN
cord-022561-rv5j1201	2024	24	suggests	suggest	VBZ
cord-022561-rv5j1201	2024	25	that	that	IN
cord-022561-rv5j1201	2024	26	radiotherapy	radiotherapy	NN
cord-022561-rv5j1201	2024	27	can	can	MD
cord-022561-rv5j1201	2024	28	induce	induce	VB
cord-022561-rv5j1201	2024	29	a	a	DT
cord-022561-rv5j1201	2024	30	cascade	cascade	NN
cord-022561-rv5j1201	2024	31	of	of	IN
cord-022561-rv5j1201	2024	32	proimmunogenic	proimmunogenic	NN
cord-022561-rv5j1201	2024	33	effects	effect	NNS
cord-022561-rv5j1201	2024	34	that	that	WDT
cord-022561-rv5j1201	2024	35	engage	engage	VBP
cord-022561-rv5j1201	2024	36	the	the	DT
cord-022561-rv5j1201	2024	37	innate	innate	JJ
cord-022561-rv5j1201	2024	38	and	and	CC
cord-022561-rv5j1201	2024	39	adaptive	adaptive	JJ
cord-022561-rv5j1201	2024	40	immune	immune	JJ
cord-022561-rv5j1201	2024	41	systems	system	NNS
cord-022561-rv5j1201	2024	42	to	to	TO
cord-022561-rv5j1201	2024	43	contribute	contribute	VB
cord-022561-rv5j1201	2024	44	to	to	IN
cord-022561-rv5j1201	2024	45	the	the	DT
cord-022561-rv5j1201	2024	46	destruction	destruction	NN
cord-022561-rv5j1201	2024	47	of	of	IN
cord-022561-rv5j1201	2024	48	tumor	tumor	NN
cord-022561-rv5j1201	2024	49	cells	cell	NNS
cord-022561-rv5j1201	2024	50	.	.	.
cord-022561-rv5j1201	2025	1	Malnutrition	malnutrition	NN
cord-022561-rv5j1201	2025	2	and	and	CC
cord-022561-rv5j1201	2025	3	cachexia	cachexia	NN
cord-022561-rv5j1201	2025	4	,	,	,
cord-022561-rv5j1201	2025	5	which	which	WDT
cord-022561-rv5j1201	2025	6	may	may	MD
cord-022561-rv5j1201	2025	7	occur	occur	VB
cord-022561-rv5j1201	2025	8	with	with	IN
cord-022561-rv5j1201	2025	9	cancer	cancer	NN
cord-022561-rv5j1201	2025	10	,	,	,
cord-022561-rv5j1201	2025	11	lead	lead	VBP
cord-022561-rv5j1201	2025	12	to	to	IN
cord-022561-rv5j1201	2025	13	secondary	secondary	JJ
cord-022561-rv5j1201	2025	14	immunosuppression	immunosuppression	NN
cord-022561-rv5j1201	2025	15	through	through	IN
cord-022561-rv5j1201	2025	16	several	several	JJ
cord-022561-rv5j1201	2025	17	complex	complex	JJ
cord-022561-rv5j1201	2025	18	metabolic	metabolic	JJ
cord-022561-rv5j1201	2025	19	and	and	CC
cord-022561-rv5j1201	2025	20	neurohormonal	neurohormonal	JJ
cord-022561-rv5j1201	2025	21	aberrations	aberration	NNS
cord-022561-rv5j1201	2025	22	.	.	.
cord-022561-rv5j1201	2026	1	Thymic	thymic	JJ
cord-022561-rv5j1201	2026	2	function	function	NN
cord-022561-rv5j1201	2026	3	may	may	MD
cord-022561-rv5j1201	2026	4	be	be	VB
cord-022561-rv5j1201	2026	5	impaired	impair	VBN
cord-022561-rv5j1201	2026	6	in	in	IN
cord-022561-rv5j1201	2026	7	young	young	JJ
cord-022561-rv5j1201	2026	8	malnourished	malnourished	JJ
cord-022561-rv5j1201	2026	9	animals	animal	NNS
cord-022561-rv5j1201	2026	10	,	,	,
cord-022561-rv5j1201	2026	11	resulting	result	VBG
cord-022561-rv5j1201	2026	12	in	in	IN
cord-022561-rv5j1201	2026	13	a	a	DT
cord-022561-rv5j1201	2026	14	decrease	decrease	NN
cord-022561-rv5j1201	2026	15	in	in	IN
cord-022561-rv5j1201	2026	16	circulating	circulate	VBG
cord-022561-rv5j1201	2026	17	T	t	NN
cord-022561-rv5j1201	2026	18	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	2026	19	and	and	CC
cord-022561-rv5j1201	2026	20	subsequent	subsequent	JJ
cord-022561-rv5j1201	2026	21	depletion	depletion	NN
cord-022561-rv5j1201	2026	22	of	of	IN
cord-022561-rv5j1201	2026	23	T	t	NN
cord-022561-rv5j1201	2026	24	lymphocyte	lymphocyte	NN
cord-022561-rv5j1201	2026	25	regions	region	NNS
cord-022561-rv5j1201	2026	26	of	of	IN
cord-022561-rv5j1201	2026	27	secondary	secondary	JJ
cord-022561-rv5j1201	2026	28	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	2026	29	organs	organ	NNS
cord-022561-rv5j1201	2026	30	.	.	.
cord-022561-rv5j1201	2027	1	Lymphoid	lymphoid	JJ
cord-022561-rv5j1201	2027	2	atrophy	atrophy	NN
cord-022561-rv5j1201	2027	3	may	may	MD
cord-022561-rv5j1201	2027	4	result	result	VB
cord-022561-rv5j1201	2027	5	from	from	IN
cord-022561-rv5j1201	2027	6	physiologic	physiologic	JJ
cord-022561-rv5j1201	2027	7	and	and	CC
cord-022561-rv5j1201	2027	8	emotional	emotional	JJ
cord-022561-rv5j1201	2027	9	stress	stress	NN
cord-022561-rv5j1201	2027	10	,	,	,
cord-022561-rv5j1201	2027	11	which	which	WDT
cord-022561-rv5j1201	2027	12	can	can	MD
cord-022561-rv5j1201	2027	13	cause	cause	VB
cord-022561-rv5j1201	2027	14	the	the	DT
cord-022561-rv5j1201	2027	15	release	release	NN
cord-022561-rv5j1201	2027	16	of	of	IN
cord-022561-rv5j1201	2027	17	catecholamines	catecholamine	NNS
cord-022561-rv5j1201	2027	18	and	and	CC
cord-022561-rv5j1201	2027	19	glucocorticoids	glucocorticoid	NNS
cord-022561-rv5j1201	2027	20	.	.	.
cord-022561-rv5j1201	2028	1	As	as	IN
cord-022561-rv5j1201	2028	2	part	part	NN
cord-022561-rv5j1201	2028	3	of	of	IN
cord-022561-rv5j1201	2028	4	the	the	DT
cord-022561-rv5j1201	2028	5	general	general	JJ
cord-022561-rv5j1201	2028	6	effects	effect	NNS
cord-022561-rv5j1201	2028	7	of	of	IN
cord-022561-rv5j1201	2028	8	aging	age	VBG
cord-022561-rv5j1201	2028	9	in	in	IN
cord-022561-rv5j1201	2028	10	cells	cell	NNS
cord-022561-rv5j1201	2028	11	(	(	-LRB-
cord-022561-rv5j1201	2028	12	see	see	VB
cord-022561-rv5j1201	2028	13	Chapter	chapter	NN
cord-022561-rv5j1201	2028	14	1	1	CD
cord-022561-rv5j1201	2028	15	)	)	-RRB-
cord-022561-rv5j1201	2028	16	,	,	,
cord-022561-rv5j1201	2028	17	all	all	DT
cord-022561-rv5j1201	2028	18	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	2028	19	organs	organ	NNS
cord-022561-rv5j1201	2028	20	decrease	decrease	VBP
cord-022561-rv5j1201	2028	21	in	in	IN
cord-022561-rv5j1201	2028	22	size	size	NN
cord-022561-rv5j1201	2028	23	(	(	-LRB-
cord-022561-rv5j1201	2028	24	atrophy	atrophy	NN
cord-022561-rv5j1201	2028	25	)	)	-RRB-
cord-022561-rv5j1201	2028	26	with	with	IN
cord-022561-rv5j1201	2028	27	advancing	advance	VBG
cord-022561-rv5j1201	2028	28	age	age	NN
cord-022561-rv5j1201	2028	29	.	.	.
cord-022561-rv5j1201	2029	1	In	in	IN
cord-022561-rv5j1201	2029	2	the	the	DT
cord-022561-rv5j1201	2029	3	case	case	NN
cord-022561-rv5j1201	2029	4	of	of	IN
cord-022561-rv5j1201	2029	5	the	the	DT
cord-022561-rv5j1201	2029	6	thymus	thymus	NN
cord-022561-rv5j1201	2029	7	this	this	DT
cord-022561-rv5j1201	2029	8	reduction	reduction	NN
cord-022561-rv5j1201	2029	9	in	in	IN
cord-022561-rv5j1201	2029	10	size	size	NN
cord-022561-rv5j1201	2029	11	occurs	occur	VBZ
cord-022561-rv5j1201	2029	12	normally	normally	RB
cord-022561-rv5j1201	2029	13	after	after	IN
cord-022561-rv5j1201	2029	14	sexual	sexual	JJ
cord-022561-rv5j1201	2029	15	maturity	maturity	NN
cord-022561-rv5j1201	2029	16	and	and	CC
cord-022561-rv5j1201	2029	17	is	be	VBZ
cord-022561-rv5j1201	2029	18	more	more	RBR
cord-022561-rv5j1201	2029	19	appropriately	appropriately	RB
cord-022561-rv5j1201	2029	20	termed	term	VBN
cord-022561-rv5j1201	2029	21	thymic	thymic	JJ
cord-022561-rv5j1201	2029	22	involution	involution	NN
cord-022561-rv5j1201	2029	23	.	.	.
cord-022561-rv5j1201	2030	1	The	the	DT
cord-022561-rv5j1201	2030	2	term	term	NN
cord-022561-rv5j1201	2030	3	involution	involution	NN
cord-022561-rv5j1201	2030	4	should	should	MD
cord-022561-rv5j1201	2030	5	be	be	VB
cord-022561-rv5j1201	2030	6	reserved	reserve	VBN
cord-022561-rv5j1201	2030	7	for	for	IN
cord-022561-rv5j1201	2030	8	normal	normal	JJ
cord-022561-rv5j1201	2030	9	physiologic	physiologic	JJ
cord-022561-rv5j1201	2030	10	processes	process	NNS
cord-022561-rv5j1201	2030	11	in	in	IN
cord-022561-rv5j1201	2030	12	which	which	WDT
cord-022561-rv5j1201	2030	13	an	an	DT
cord-022561-rv5j1201	2030	14	organ	organ	NN
cord-022561-rv5j1201	2030	15	either	either	DT
cord-022561-rv5j1201	2030	16	returns	return	VBZ
cord-022561-rv5j1201	2030	17	to	to	IN
cord-022561-rv5j1201	2030	18	normal	normal	JJ
cord-022561-rv5j1201	2030	19	size	size	NN
cord-022561-rv5j1201	2030	20	after	after	IN
cord-022561-rv5j1201	2030	21	a	a	DT
cord-022561-rv5j1201	2030	22	period	period	NN
cord-022561-rv5j1201	2030	23	of	of	IN
cord-022561-rv5j1201	2030	24	enlargement	enlargement	NN
cord-022561-rv5j1201	2030	25	(	(	-LRB-
cord-022561-rv5j1201	2030	26	e.g.	e.g.	RB
cord-022561-rv5j1201	2030	27	,	,	,
cord-022561-rv5j1201	2030	28	postpartum	postpartum	NN
cord-022561-rv5j1201	2030	29	uterus	uterus	NN
cord-022561-rv5j1201	2030	30	)	)	-RRB-
cord-022561-rv5j1201	2030	31	or	or	CC
cord-022561-rv5j1201	2030	32	regresses	regress	VBZ
cord-022561-rv5j1201	2030	33	to	to	IN
cord-022561-rv5j1201	2030	34	a	a	DT
cord-022561-rv5j1201	2030	35	more	more	RBR
cord-022561-rv5j1201	2030	36	primitive	primitive	JJ
cord-022561-rv5j1201	2030	37	state	state	NN
cord-022561-rv5j1201	2030	38	(	(	-LRB-
cord-022561-rv5j1201	2030	39	e.g.	e.g.	RB
cord-022561-rv5j1201	2030	40	,	,	,
cord-022561-rv5j1201	2030	41	thymic	thymic	JJ
cord-022561-rv5j1201	2030	42	involution	involution	NN
cord-022561-rv5j1201	2030	43	)	)	-RRB-
cord-022561-rv5j1201	2030	44	.	.	.
cord-022561-rv5j1201	2031	1	Because	because	IN
cord-022561-rv5j1201	2031	2	the	the	DT
cord-022561-rv5j1201	2031	3	thymus	thymus	NN
cord-022561-rv5j1201	2031	4	has	have	VBZ
cord-022561-rv5j1201	2031	5	both	both	DT
cord-022561-rv5j1201	2031	6	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	2031	7	and	and	CC
cord-022561-rv5j1201	2031	8	epithelial	epithelial	JJ
cord-022561-rv5j1201	2031	9	components	component	NNS
cord-022561-rv5j1201	2031	10	,	,	,
cord-022561-rv5j1201	2031	11	neoplasms	neoplasm	NNS
cord-022561-rv5j1201	2031	12	may	may	MD
cord-022561-rv5j1201	2031	13	arise	arise	VB
cord-022561-rv5j1201	2031	14	from	from	IN
cord-022561-rv5j1201	2031	15	either	either	DT
cord-022561-rv5j1201	2031	16	component	component	NN
cord-022561-rv5j1201	2031	17	.	.	.
cord-022561-rv5j1201	2032	1	Thymic	thymic	JJ
cord-022561-rv5j1201	2032	2	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2032	3	arises	arise	VBZ
cord-022561-rv5j1201	2032	4	from	from	IN
cord-022561-rv5j1201	2032	5	the	the	DT
cord-022561-rv5j1201	2032	6	T	t	NN
cord-022561-rv5j1201	2032	7	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	2032	8	in	in	IN
cord-022561-rv5j1201	2032	9	the	the	DT
cord-022561-rv5j1201	2032	10	thymus	thymus	NN
cord-022561-rv5j1201	2032	11	(	(	-LRB-
cord-022561-rv5j1201	2032	12	and	and	CC
cord-022561-rv5j1201	2032	13	very	very	RB
cord-022561-rv5j1201	2032	14	rarely	rarely	RB
cord-022561-rv5j1201	2032	15	B	b	NN
cord-022561-rv5j1201	2032	16	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	2032	17	)	)	-RRB-
cord-022561-rv5j1201	2032	18	.	.	.
cord-022561-rv5j1201	2033	1	It	-PRON-	PRP
cord-022561-rv5j1201	2033	2	is	be	VBZ
cord-022561-rv5j1201	2033	3	most	most	RBS
cord-022561-rv5j1201	2033	4	often	often	RB
cord-022561-rv5j1201	2033	5	seen	see	VBN
cord-022561-rv5j1201	2033	6	in	in	IN
cord-022561-rv5j1201	2033	7	young	young	JJ
cord-022561-rv5j1201	2033	8	cats	cat	NNS
cord-022561-rv5j1201	2033	9	and	and	CC
cord-022561-rv5j1201	2033	10	cattle	cattle	NNS
cord-022561-rv5j1201	2033	11	and	and	CC
cord-022561-rv5j1201	2033	12	less	less	RBR
cord-022561-rv5j1201	2033	13	frequently	frequently	RB
cord-022561-rv5j1201	2033	14	in	in	IN
cord-022561-rv5j1201	2033	15	dogs	dog	NNS
cord-022561-rv5j1201	2033	16	(	(	-LRB-
cord-022561-rv5j1201	2033	17	Fig	Fig	NNP
cord-022561-rv5j1201	2033	18	.	.	.
cord-022561-rv5j1201	2033	19	13	13	CD
cord-022561-rv5j1201	2033	20	-	-	SYM
cord-022561-rv5j1201	2033	21	53	53	CD
cord-022561-rv5j1201	2033	22	)	)	-RRB-
cord-022561-rv5j1201	2033	23	(	(	-LRB-
cord-022561-rv5j1201	2033	24	see	see	VB
cord-022561-rv5j1201	2033	25	Hematopoietic	Hematopoietic	NNP
cord-022561-rv5j1201	2033	26	Neoplasia	Neoplasia	NNP
cord-022561-rv5j1201	2033	27	)	)	-RRB-
cord-022561-rv5j1201	2033	28	.	.	.
cord-022561-rv5j1201	2034	1	Thymomas	thymoma	NNS
cord-022561-rv5j1201	2034	2	arise	arise	VBP
cord-022561-rv5j1201	2034	3	from	from	IN
cord-022561-rv5j1201	2034	4	the	the	DT
cord-022561-rv5j1201	2034	5	epithelial	epithelial	JJ
cord-022561-rv5j1201	2034	6	component	component	NN
cord-022561-rv5j1201	2034	7	and	and	CC
cord-022561-rv5j1201	2034	8	are	be	VBP
cord-022561-rv5j1201	2034	9	usually	usually	RB
cord-022561-rv5j1201	2034	10	benign	benign	JJ
cord-022561-rv5j1201	2034	11	neoplasms	neoplasm	NNS
cord-022561-rv5j1201	2034	12	that	that	WDT
cord-022561-rv5j1201	2034	13	occupy	occupy	VBP
cord-022561-rv5j1201	2034	14	the	the	DT
cord-022561-rv5j1201	2034	15	cranial	cranial	JJ
cord-022561-rv5j1201	2034	16	mediastinum	mediastinum	NN
cord-022561-rv5j1201	2034	17	of	of	IN
cord-022561-rv5j1201	2034	18	older	old	JJR
cord-022561-rv5j1201	2034	19	animals	animal	NNS
cord-022561-rv5j1201	2034	20	.	.	.
cord-022561-rv5j1201	2035	1	Histologically	histologically	RB
cord-022561-rv5j1201	2035	2	,	,	,
cord-022561-rv5j1201	2035	3	these	these	DT
cord-022561-rv5j1201	2035	4	neoplasms	neoplasm	NNS
cord-022561-rv5j1201	2035	5	consist	consist	VBP
cord-022561-rv5j1201	2035	6	of	of	IN
cord-022561-rv5j1201	2035	7	clustered	clustered	JJ
cord-022561-rv5j1201	2035	8	or	or	CC
cord-022561-rv5j1201	2035	9	individualized	individualized	JJ
cord-022561-rv5j1201	2035	10	neoplastic	neoplastic	JJ
cord-022561-rv5j1201	2035	11	epithelial	epithelial	JJ
cord-022561-rv5j1201	2035	12	cells	cell	NNS
cord-022561-rv5j1201	2035	13	,	,	,
cord-022561-rv5j1201	2035	14	often	often	RB
cord-022561-rv5j1201	2035	15	outnumbered	outnumber	VBN
cord-022561-rv5j1201	2035	16	by	by	IN
cord-022561-rv5j1201	2035	17	nonneoplastic	nonneoplastic	JJ
cord-022561-rv5j1201	2035	18	small	small	JJ
cord-022561-rv5j1201	2035	19	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	2035	20	(	(	-LRB-
cord-022561-rv5j1201	2035	21	"	"	``
cord-022561-rv5j1201	2035	22	lymphocyte	lymphocyte	NN
cord-022561-rv5j1201	2035	23	-	-	HYPH
cord-022561-rv5j1201	2035	24	rich	rich	JJ
cord-022561-rv5j1201	2035	25	thymoma	thymoma	NN
cord-022561-rv5j1201	2035	26	"	"	''
cord-022561-rv5j1201	2035	27	)	)	-RRB-
cord-022561-rv5j1201	2035	28	.	.	.
cord-022561-rv5j1201	2036	1	Thymomas	Thymomas	NNP
cord-022561-rv5j1201	2036	2	are	be	VBP
cord-022561-rv5j1201	2036	3	common	common	JJ
cord-022561-rv5j1201	2036	4	in	in	IN
cord-022561-rv5j1201	2036	5	goats	goat	NNS
cord-022561-rv5j1201	2036	6	and	and	CC
cord-022561-rv5j1201	2036	7	often	often	RB
cord-022561-rv5j1201	2036	8	contain	contain	VBP
cord-022561-rv5j1201	2036	9	large	large	JJ
cord-022561-rv5j1201	2036	10	cystic	cystic	JJ
cord-022561-rv5j1201	2036	11	structures	structure	NNS
cord-022561-rv5j1201	2036	12	.	.	.
cord-022561-rv5j1201	2037	1	Immunemediated	immunemediated	JJ
cord-022561-rv5j1201	2037	2	diseases	disease	NNS
cord-022561-rv5j1201	2037	3	,	,	,
cord-022561-rv5j1201	2037	4	including	include	VBG
cord-022561-rv5j1201	2037	5	myasthenia	myasthenia	NN
cord-022561-rv5j1201	2037	6	gravis	gravis	NNP
cord-022561-rv5j1201	2037	7	and	and	CC
cord-022561-rv5j1201	2037	8	immunemediated	immunemediated	NNP
cord-022561-rv5j1201	2037	9	polymyositis	polymyositis	NNP
cord-022561-rv5j1201	2037	10	,	,	,
cord-022561-rv5j1201	2037	11	occur	occur	VBP
cord-022561-rv5j1201	2037	12	with	with	IN
cord-022561-rv5j1201	2037	13	thymomas	thymoma	NNS
cord-022561-rv5j1201	2037	14	in	in	IN
cord-022561-rv5j1201	2037	15	dogs	dog	NNS
cord-022561-rv5j1201	2037	16	,	,	,
cord-022561-rv5j1201	2037	17	and	and	CC
cord-022561-rv5j1201	2037	18	also	also	RB
cord-022561-rv5j1201	2037	19	rarely	rarely	RB
cord-022561-rv5j1201	2037	20	in	in	IN
cord-022561-rv5j1201	2037	21	cats	cat	NNS
cord-022561-rv5j1201	2037	22	.	.	.
cord-022561-rv5j1201	2038	1	Myasthenia	myasthenia	NN
cord-022561-rv5j1201	2038	2	gravis	gravis	NN
cord-022561-rv5j1201	2038	3	is	be	VBZ
cord-022561-rv5j1201	2038	4	caused	cause	VBN
cord-022561-rv5j1201	2038	5	by	by	IN
cord-022561-rv5j1201	2038	6	autoantibodies	autoantibody	NNS
cord-022561-rv5j1201	2038	7	directed	direct	VBN
cord-022561-rv5j1201	2038	8	toward	toward	IN
cord-022561-rv5j1201	2038	9	the	the	DT
cord-022561-rv5j1201	2038	10	acetylcholine	acetylcholine	NN
cord-022561-rv5j1201	2038	11	receptors	receptor	NNS
cord-022561-rv5j1201	2038	12	,	,	,
cord-022561-rv5j1201	2038	13	which	which	WDT
cord-022561-rv5j1201	2038	14	lead	lead	VBP
cord-022561-rv5j1201	2038	15	to	to	IN
cord-022561-rv5j1201	2038	16	destruction	destruction	NN
cord-022561-rv5j1201	2038	17	of	of	IN
cord-022561-rv5j1201	2038	18	postsynaptic	postsynaptic	JJ
cord-022561-rv5j1201	2038	19	membranes	membrane	NNS
cord-022561-rv5j1201	2038	20	and	and	CC
cord-022561-rv5j1201	2038	21	reduction	reduction	NN
cord-022561-rv5j1201	2038	22	of	of	IN
cord-022561-rv5j1201	2038	23	acetylcholine	acetylcholine	NN
cord-022561-rv5j1201	2038	24	receptors	receptor	NNS
cord-022561-rv5j1201	2038	25	at	at	IN
cord-022561-rv5j1201	2038	26	neuromuscular	neuromuscular	JJ
cord-022561-rv5j1201	2038	27	junction	junction	NN
cord-022561-rv5j1201	2038	28	.	.	.
cord-022561-rv5j1201	2039	1	Megaesophagus	Megaesophagus	NNP
cord-022561-rv5j1201	2039	2	and	and	CC
cord-022561-rv5j1201	2039	3	aspiration	aspiration	NN
cord-022561-rv5j1201	2039	4	pneumonia	pneumonia	NN
cord-022561-rv5j1201	2039	5	are	be	VBP
cord-022561-rv5j1201	2039	6	common	common	JJ
cord-022561-rv5j1201	2039	7	sequelae	sequela	NNS
cord-022561-rv5j1201	2039	8	to	to	IN
cord-022561-rv5j1201	2039	9	this	this	DT
cord-022561-rv5j1201	2039	10	condition	condition	NN
cord-022561-rv5j1201	2039	11	.	.	.
cord-022561-rv5j1201	2040	1	(	(	-LRB-
cord-022561-rv5j1201	2040	2	syn	syn	NN
cord-022561-rv5j1201	2040	3	:	:	:
cord-022561-rv5j1201	2040	4	necropsy	necropsy	JJ
cord-022561-rv5j1201	2040	5	)	)	-RRB-
cord-022561-rv5j1201	2040	6	in	in	IN
cord-022561-rv5j1201	2040	7	horses	horse	NNS
cord-022561-rv5j1201	2040	8	and	and	CC
cord-022561-rv5j1201	2040	9	dogs	dog	NNS
cord-022561-rv5j1201	2040	10	that	that	WDT
cord-022561-rv5j1201	2040	11	have	have	VBP
cord-022561-rv5j1201	2040	12	been	be	VBN
cord-022561-rv5j1201	2040	13	euthanized	euthanize	VBN
cord-022561-rv5j1201	2040	14	or	or	CC
cord-022561-rv5j1201	2040	15	anesthetized	anesthetize	VBN
cord-022561-rv5j1201	2040	16	with	with	IN
cord-022561-rv5j1201	2040	17	barbiturates	barbiturate	NNS
cord-022561-rv5j1201	2040	18	.	.	.
cord-022561-rv5j1201	2041	1	Grossly	grossly	RB
cord-022561-rv5j1201	2041	2	,	,	,
cord-022561-rv5j1201	2041	3	the	the	DT
cord-022561-rv5j1201	2041	4	spleen	spleen	NN
cord-022561-rv5j1201	2041	5	is	be	VBZ
cord-022561-rv5j1201	2041	6	extremely	extremely	RB
cord-022561-rv5j1201	2041	7	enlarged	enlarged	JJ
cord-022561-rv5j1201	2041	8	(	(	-LRB-
cord-022561-rv5j1201	2041	9	Fig	Fig	NNP
cord-022561-rv5j1201	2041	10	.	.	.
cord-022561-rv5j1201	2041	11	13	13	CD
cord-022561-rv5j1201	2041	12	-	-	SYM
cord-022561-rv5j1201	2041	13	55	55	CD
cord-022561-rv5j1201	2041	14	)	)	-RRB-
cord-022561-rv5j1201	2041	15	,	,	,
cord-022561-rv5j1201	2041	16	and	and	CC
cord-022561-rv5j1201	2041	17	the	the	DT
cord-022561-rv5j1201	2041	18	cut	cut	NN
cord-022561-rv5j1201	2041	19	surface	surface	NN
cord-022561-rv5j1201	2041	20	bulges	bulge	NNS
cord-022561-rv5j1201	2041	21	and	and	CC
cord-022561-rv5j1201	2041	22	oozes	ooze	VBZ
cord-022561-rv5j1201	2041	23	copious	copious	JJ
cord-022561-rv5j1201	2041	24	blood	blood	NN
cord-022561-rv5j1201	2041	25	.	.	.
cord-022561-rv5j1201	2042	1	Because	because	IN
cord-022561-rv5j1201	2042	2	of	of	IN
cord-022561-rv5j1201	2042	3	the	the	DT
cord-022561-rv5j1201	2042	4	splenic	splenic	JJ
cord-022561-rv5j1201	2042	5	distention	distention	NN
cord-022561-rv5j1201	2042	6	,	,	,
cord-022561-rv5j1201	2042	7	the	the	DT
cord-022561-rv5j1201	2042	8	splenic	splenic	JJ
cord-022561-rv5j1201	2042	9	capsule	capsule	NN
cord-022561-rv5j1201	2042	10	can	can	MD
cord-022561-rv5j1201	2042	11	be	be	VB
cord-022561-rv5j1201	2042	12	fragile	fragile	JJ
cord-022561-rv5j1201	2042	13	and	and	CC
cord-022561-rv5j1201	2042	14	easily	easily	RB
cord-022561-rv5j1201	2042	15	ruptured	rupture	VBN
cord-022561-rv5j1201	2042	16	.	.	.
cord-022561-rv5j1201	2043	1	Histologically	histologically	RB
cord-022561-rv5j1201	2043	2	,	,	,
cord-022561-rv5j1201	2043	3	the	the	DT
cord-022561-rv5j1201	2043	4	red	red	JJ
cord-022561-rv5j1201	2043	5	pulp	pulp	NN
cord-022561-rv5j1201	2043	6	is	be	VBZ
cord-022561-rv5j1201	2043	7	distended	distend	VBN
cord-022561-rv5j1201	2043	8	by	by	IN
cord-022561-rv5j1201	2043	9	erythrocytes	erythrocyte	NNS
cord-022561-rv5j1201	2043	10	,	,	,
cord-022561-rv5j1201	2043	11	and	and	CC
cord-022561-rv5j1201	2043	12	the	the	DT
cord-022561-rv5j1201	2043	13	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	2043	14	tissues	tissue	NNS
cord-022561-rv5j1201	2043	15	of	of	IN
cord-022561-rv5j1201	2043	16	the	the	DT
cord-022561-rv5j1201	2043	17	white	white	JJ
cord-022561-rv5j1201	2043	18	pulp	pulp	NN
cord-022561-rv5j1201	2043	19	are	be	VBP
cord-022561-rv5j1201	2043	20	small	small	JJ
cord-022561-rv5j1201	2043	21	and	and	CC
cord-022561-rv5j1201	2043	22	widely	widely	RB
cord-022561-rv5j1201	2043	23	separated	separate	VBN
cord-022561-rv5j1201	2043	24	(	(	-LRB-
cord-022561-rv5j1201	2043	25	Fig	Fig	NNP
cord-022561-rv5j1201	2043	26	.	.	.
cord-022561-rv5j1201	2043	27	13	13	CD
cord-022561-rv5j1201	2043	28	-	-	SYM
cord-022561-rv5j1201	2043	29	56	56	CD
cord-022561-rv5j1201	2043	30	)	)	-RRB-
cord-022561-rv5j1201	2043	31	.	.	.
cord-022561-rv5j1201	2044	1	Electric	electric	JJ
cord-022561-rv5j1201	2044	2	stunning	stunning	JJ
cord-022561-rv5j1201	2044	3	of	of	IN
cord-022561-rv5j1201	2044	4	pigs	pig	NNS
cord-022561-rv5j1201	2044	5	at	at	IN
cord-022561-rv5j1201	2044	6	slaughter	slaughter	NN
cord-022561-rv5j1201	2044	7	may	may	MD
cord-022561-rv5j1201	2044	8	result	result	VB
cord-022561-rv5j1201	2044	9	in	in	IN
cord-022561-rv5j1201	2044	10	a	a	DT
cord-022561-rv5j1201	2044	11	large	large	JJ
cord-022561-rv5j1201	2044	12	congested	congested	JJ
cord-022561-rv5j1201	2044	13	spleen	spleen	NN
cord-022561-rv5j1201	2044	14	;	;	:
cord-022561-rv5j1201	2044	15	the	the	DT
cord-022561-rv5j1201	2044	16	mechanism	mechanism	NN
cord-022561-rv5j1201	2044	17	is	be	VBZ
cord-022561-rv5j1201	2044	18	unknown	unknown	JJ
cord-022561-rv5j1201	2044	19	,	,	,
cord-022561-rv5j1201	2044	20	but	but	CC
cord-022561-rv5j1201	2044	21	it	-PRON-	PRP
cord-022561-rv5j1201	2044	22	should	should	MD
cord-022561-rv5j1201	2044	23	not	not	RB
cord-022561-rv5j1201	2044	24	be	be	VB
cord-022561-rv5j1201	2044	25	confused	confuse	VBN
cord-022561-rv5j1201	2044	26	with	with	IN
cord-022561-rv5j1201	2044	27	a	a	DT
cord-022561-rv5j1201	2044	28	pathologically	pathologically	RB
cord-022561-rv5j1201	2044	29	congested	congested	JJ
cord-022561-rv5j1201	2044	30	spleen	spleen	NNS
cord-022561-rv5j1201	2044	31	.	.	.
cord-022561-rv5j1201	2045	1	Splenic	splenic	JJ
cord-022561-rv5j1201	2045	2	congestion	congestion	NN
cord-022561-rv5j1201	2045	3	in	in	IN
cord-022561-rv5j1201	2045	4	acute	acute	JJ
cord-022561-rv5j1201	2045	5	cardiac	cardiac	JJ
cord-022561-rv5j1201	2045	6	failure	failure	NN
cord-022561-rv5j1201	2045	7	is	be	VBZ
cord-022561-rv5j1201	2045	8	rarely	rarely	RB
cord-022561-rv5j1201	2045	9	seen	see	VBN
cord-022561-rv5j1201	2045	10	in	in	IN
cord-022561-rv5j1201	2045	11	animals	animal	NNS
cord-022561-rv5j1201	2045	12	.	.	.
cord-022561-rv5j1201	2046	1	Acute	acute	JJ
cord-022561-rv5j1201	2046	2	Congestion	Congestion	NNP
cord-022561-rv5j1201	2046	3	/	/	SYM
cord-022561-rv5j1201	2046	4	Hyperemia	Hyperemia	NNP
cord-022561-rv5j1201	2046	5	.	.	.
cord-022561-rv5j1201	2047	1	Acute	acute	JJ
cord-022561-rv5j1201	2047	2	septicemias	septicemias	NNP
cord-022561-rv5j1201	2047	3	may	may	MD
cord-022561-rv5j1201	2047	4	cause	cause	VB
cord-022561-rv5j1201	2047	5	acute	acute	JJ
cord-022561-rv5j1201	2047	6	hyperemia	hyperemia	NN
cord-022561-rv5j1201	2047	7	and	and	CC
cord-022561-rv5j1201	2047	8	concurrent	concurrent	JJ
cord-022561-rv5j1201	2047	9	acute	acute	JJ
cord-022561-rv5j1201	2047	10	congestion	congestion	NN
cord-022561-rv5j1201	2047	11	of	of	IN
cord-022561-rv5j1201	2047	12	marginal	marginal	JJ
cord-022561-rv5j1201	2047	13	zones	zone	NNS
cord-022561-rv5j1201	2047	14	and	and	CC
cord-022561-rv5j1201	2047	15	splenic	splenic	JJ
cord-022561-rv5j1201	2047	16	red	red	JJ
cord-022561-rv5j1201	2047	17	pulp	pulp	NN
cord-022561-rv5j1201	2047	18	.	.	.
cord-022561-rv5j1201	2048	1	Microbes	microbe	NNS
cord-022561-rv5j1201	2048	2	are	be	VBP
cord-022561-rv5j1201	2048	3	transported	transport	VBN
cord-022561-rv5j1201	2048	4	hematogenously	hematogenously	RB
cord-022561-rv5j1201	2048	5	to	to	IN
cord-022561-rv5j1201	2048	6	these	these	DT
cord-022561-rv5j1201	2048	7	sites	site	NNS
cord-022561-rv5j1201	2048	8	,	,	,
cord-022561-rv5j1201	2048	9	where	where	WRB
cord-022561-rv5j1201	2048	10	they	-PRON-	PRP
cord-022561-rv5j1201	2048	11	are	be	VBP
cord-022561-rv5j1201	2048	12	rapidly	rapidly	RB
cord-022561-rv5j1201	2048	13	phagocytized	phagocytize	VBN
cord-022561-rv5j1201	2048	14	by	by	IN
cord-022561-rv5j1201	2048	15	macrophages	macrophage	NNS
cord-022561-rv5j1201	2048	16	.	.	.
cord-022561-rv5j1201	2049	1	Enormous	enormous	JJ
cord-022561-rv5j1201	2049	2	numbers	number	NNS
cord-022561-rv5j1201	2049	3	of	of	IN
cord-022561-rv5j1201	2049	4	intravenous	intravenous	JJ
cord-022561-rv5j1201	2049	5	bacteria	bacteria	NNS
cord-022561-rv5j1201	2049	6	can	can	MD
cord-022561-rv5j1201	2049	7	be	be	VB
cord-022561-rv5j1201	2049	8	cleared	clear	VBN
cord-022561-rv5j1201	2049	9	by	by	IN
cord-022561-rv5j1201	2049	10	the	the	DT
cord-022561-rv5j1201	2049	11	spleen	spleen	NNS
cord-022561-rv5j1201	2049	12	from	from	IN
cord-022561-rv5j1201	2049	13	the	the	DT
cord-022561-rv5j1201	2049	14	blood	blood	NN
cord-022561-rv5j1201	2049	15	in	in	IN
cord-022561-rv5j1201	2049	16	20	20	CD
cord-022561-rv5j1201	2049	17	to	to	TO
cord-022561-rv5j1201	2049	18	30	30	CD
cord-022561-rv5j1201	2049	19	minutes	minute	NNS
cord-022561-rv5j1201	2049	20	,	,	,
cord-022561-rv5j1201	2049	21	but	but	CC
cord-022561-rv5j1201	2049	22	when	when	WRB
cord-022561-rv5j1201	2049	23	this	this	DT
cord-022561-rv5j1201	2049	24	defensive	defensive	JJ
cord-022561-rv5j1201	2049	25	mechanism	mechanism	NN
cord-022561-rv5j1201	2049	26	is	be	VBZ
cord-022561-rv5j1201	2049	27	overwhelmed	overwhelmed	JJ
cord-022561-rv5j1201	2049	28	,	,	,
cord-022561-rv5j1201	2049	29	the	the	DT
cord-022561-rv5j1201	2049	30	outcome	outcome	NN
cord-022561-rv5j1201	2049	31	is	be	VBZ
cord-022561-rv5j1201	2049	32	usually	usually	RB
cord-022561-rv5j1201	2049	33	fatal	fatal	JJ
cord-022561-rv5j1201	2049	34	.	.	.
cord-022561-rv5j1201	2050	1	The	the	DT
cord-022561-rv5j1201	2050	2	response	response	NN
cord-022561-rv5j1201	2050	3	of	of	IN
cord-022561-rv5j1201	2050	4	the	the	DT
cord-022561-rv5j1201	2050	5	spleen	spleen	NN
cord-022561-rv5j1201	2050	6	depends	depend	VBZ
cord-022561-rv5j1201	2050	7	on	on	IN
cord-022561-rv5j1201	2050	8	the	the	DT
cord-022561-rv5j1201	2050	9	duration	duration	NN
cord-022561-rv5j1201	2050	10	of	of	IN
cord-022561-rv5j1201	2050	11	the	the	DT
cord-022561-rv5j1201	2050	12	disease	disease	NN
cord-022561-rv5j1201	2050	13	.	.	.
cord-022561-rv5j1201	2051	1	In	in	IN
cord-022561-rv5j1201	2051	2	acutely	acutely	RB
cord-022561-rv5j1201	2051	3	fatal	fatal	JJ
cord-022561-rv5j1201	2051	4	cases	case	NNS
cord-022561-rv5j1201	2051	5	,	,	,
cord-022561-rv5j1201	2051	6	such	such	JJ
cord-022561-rv5j1201	2051	7	as	as	IN
cord-022561-rv5j1201	2051	8	anthrax	anthrax	NN
cord-022561-rv5j1201	2051	9	and	and	CC
cord-022561-rv5j1201	2051	10	fulminating	fulminate	VBG
cord-022561-rv5j1201	2051	11	salmonellosis	salmonellosis	NN
cord-022561-rv5j1201	2051	12	,	,	,
cord-022561-rv5j1201	2051	13	distention	distention	NN
cord-022561-rv5j1201	2051	14	by	by	IN
cord-022561-rv5j1201	2051	15	blood	blood	NN
cord-022561-rv5j1201	2051	16	may	may	MD
cord-022561-rv5j1201	2051	17	be	be	VB
cord-022561-rv5j1201	2051	18	the	the	DT
cord-022561-rv5j1201	2051	19	only	only	JJ
cord-022561-rv5j1201	2051	20	gross	gross	JJ
cord-022561-rv5j1201	2051	21	finding	finding	NN
cord-022561-rv5j1201	2051	22	.	.	.
cord-022561-rv5j1201	2052	1	If	if	IN
cord-022561-rv5j1201	2052	2	the	the	DT
cord-022561-rv5j1201	2052	3	animal	animal	NN
cord-022561-rv5j1201	2052	4	survives	survive	VBZ
cord-022561-rv5j1201	2052	5	longer	long	RBR
cord-022561-rv5j1201	2052	6	,	,	,
cord-022561-rv5j1201	2052	7	as	as	IN
cord-022561-rv5j1201	2052	8	in	in	IN
cord-022561-rv5j1201	2052	9	swine	swine	NN
cord-022561-rv5j1201	2052	10	erysipelas	erysipela	NNS
cord-022561-rv5j1201	2052	11	and	and	CC
cord-022561-rv5j1201	2052	12	the	the	DT
cord-022561-rv5j1201	2052	13	less	less	RBR
cord-022561-rv5j1201	2052	14	virulent	virulent	JJ
cord-022561-rv5j1201	2052	15	forms	form	NNS
cord-022561-rv5j1201	2052	16	of	of	IN
cord-022561-rv5j1201	2052	17	[	[	-LRB-
cord-022561-rv5j1201	2052	18	all	all	DT
cord-022561-rv5j1201	2052	19	of	of	IN
cord-022561-rv5j1201	2052	20	which	which	WDT
cord-022561-rv5j1201	2052	21	compress	compress	VBP
cord-022561-rv5j1201	2052	22	the	the	DT
cord-022561-rv5j1201	2052	23	splenic	splenic	JJ
cord-022561-rv5j1201	2052	24	vein	vein	NN
cord-022561-rv5j1201	2052	25	]	]	-RRB-
cord-022561-rv5j1201	2052	26	,	,	,
cord-022561-rv5j1201	2052	27	and	and	CC
cord-022561-rv5j1201	2052	28	barbiturate	barbiturate	NN
cord-022561-rv5j1201	2052	29	euthanasia	euthanasia	NN
cord-022561-rv5j1201	2052	30	,	,	,
cord-022561-rv5j1201	2052	31	anesthesia	anesthesia	NN
cord-022561-rv5j1201	2052	32	,	,	,
cord-022561-rv5j1201	2052	33	or	or	CC
cord-022561-rv5j1201	2052	34	sedation	sedation	NN
cord-022561-rv5j1201	2052	35	)	)	-RRB-
cord-022561-rv5j1201	2052	36	,	,	,
cord-022561-rv5j1201	2052	37	(	(	-LRB-
cord-022561-rv5j1201	2052	38	2	2	LS
cord-022561-rv5j1201	2052	39	)	)	-RRB-
cord-022561-rv5j1201	2052	40	acute	acute	JJ
cord-022561-rv5j1201	2052	41	hyperemia	hyperemia	NN
cord-022561-rv5j1201	2052	42	(	(	-LRB-
cord-022561-rv5j1201	2052	43	due	due	IN
cord-022561-rv5j1201	2052	44	to	to	IN
cord-022561-rv5j1201	2052	45	septicemia	septicemia	NN
cord-022561-rv5j1201	2052	46	)	)	-RRB-
cord-022561-rv5j1201	2052	47	,	,	,
cord-022561-rv5j1201	2052	48	and	and	CC
cord-022561-rv5j1201	2052	49	(	(	-LRB-
cord-022561-rv5j1201	2052	50	3	3	LS
cord-022561-rv5j1201	2052	51	)	)	-RRB-
cord-022561-rv5j1201	2052	52	acute	acute	JJ
cord-022561-rv5j1201	2052	53	hemolytic	hemolytic	JJ
cord-022561-rv5j1201	2052	54	anemia	anemia	NN
cord-022561-rv5j1201	2052	55	(	(	-LRB-
cord-022561-rv5j1201	2052	56	due	due	IN
cord-022561-rv5j1201	2052	57	to	to	IN
cord-022561-rv5j1201	2052	58	an	an	DT
cord-022561-rv5j1201	2052	59	autoimmune	autoimmune	JJ
cord-022561-rv5j1201	2052	60	disorder	disorder	NN
cord-022561-rv5j1201	2052	61	or	or	CC
cord-022561-rv5j1201	2052	62	an	an	DT
cord-022561-rv5j1201	2052	63	infection	infection	NN
cord-022561-rv5j1201	2052	64	with	with	IN
cord-022561-rv5j1201	2052	65	a	a	DT
cord-022561-rv5j1201	2052	66	hemotropic	hemotropic	NNP
cord-022561-rv5j1201	2052	67	parasite	parasite	NN
cord-022561-rv5j1201	2052	68	)	)	-RRB-
cord-022561-rv5j1201	2052	69	.	.	.
cord-022561-rv5j1201	2053	1	Splenic	Splenic	NNP
cord-022561-rv5j1201	2053	2	Torsion	Torsion	NNP
cord-022561-rv5j1201	2053	3	.	.	.
cord-022561-rv5j1201	2054	1	Torsion	torsion	NN
cord-022561-rv5j1201	2054	2	of	of	IN
cord-022561-rv5j1201	2054	3	the	the	DT
cord-022561-rv5j1201	2054	4	spleen	spleen	NN
cord-022561-rv5j1201	2054	5	occurs	occur	VBZ
cord-022561-rv5j1201	2054	6	most	most	RBS
cord-022561-rv5j1201	2054	7	commonly	commonly	RB
cord-022561-rv5j1201	2054	8	in	in	IN
cord-022561-rv5j1201	2054	9	pigs	pig	NNS
cord-022561-rv5j1201	2054	10	and	and	CC
cord-022561-rv5j1201	2054	11	dogs	dog	NNS
cord-022561-rv5j1201	2054	12	;	;	:
cord-022561-rv5j1201	2054	13	in	in	IN
cord-022561-rv5j1201	2054	14	dogs	dog	NNS
cord-022561-rv5j1201	2054	15	this	this	DT
cord-022561-rv5j1201	2054	16	usually	usually	RB
cord-022561-rv5j1201	2054	17	involves	involve	VBZ
cord-022561-rv5j1201	2054	18	both	both	DT
cord-022561-rv5j1201	2054	19	spleen	spleen	NNS
cord-022561-rv5j1201	2054	20	and	and	CC
cord-022561-rv5j1201	2054	21	stomach	stomach	NN
cord-022561-rv5j1201	2054	22	and	and	CC
cord-022561-rv5j1201	2054	23	is	be	VBZ
cord-022561-rv5j1201	2054	24	seen	see	VBN
cord-022561-rv5j1201	2054	25	more	more	RBR
cord-022561-rv5j1201	2054	26	often	often	RB
cord-022561-rv5j1201	2054	27	in	in	IN
cord-022561-rv5j1201	2054	28	deep	deep	JJ
cord-022561-rv5j1201	2054	29	-	-	HYPH
cord-022561-rv5j1201	2054	30	chested	chested	JJ
cord-022561-rv5j1201	2054	31	breeds	breed	NNS
cord-022561-rv5j1201	2054	32	(	(	-LRB-
cord-022561-rv5j1201	2054	33	see	see	VB
cord-022561-rv5j1201	2054	34	Chapter	Chapter	NNP
cord-022561-rv5j1201	2054	35	7	7	CD
cord-022561-rv5j1201	2054	36	)	)	-RRB-
cord-022561-rv5j1201	2054	37	.	.	.
cord-022561-rv5j1201	2055	1	In	in	IN
cord-022561-rv5j1201	2055	2	contrast	contrast	NN
cord-022561-rv5j1201	2055	3	to	to	IN
cord-022561-rv5j1201	2055	4	ruminants	ruminant	NNS
cord-022561-rv5j1201	2055	5	,	,	,
cord-022561-rv5j1201	2055	6	in	in	IN
cord-022561-rv5j1201	2055	7	which	which	WDT
cord-022561-rv5j1201	2055	8	the	the	DT
cord-022561-rv5j1201	2055	9	spleen	spleen	NN
cord-022561-rv5j1201	2055	10	is	be	VBZ
cord-022561-rv5j1201	2055	11	firmly	firmly	RB
cord-022561-rv5j1201	2055	12	attached	attach	VBN
cord-022561-rv5j1201	2055	13	to	to	IN
cord-022561-rv5j1201	2055	14	the	the	DT
cord-022561-rv5j1201	2055	15	rumen	rumen	NN
cord-022561-rv5j1201	2055	16	,	,	,
cord-022561-rv5j1201	2055	17	the	the	DT
cord-022561-rv5j1201	2055	18	spleens	spleen	NNS
cord-022561-rv5j1201	2055	19	of	of	IN
cord-022561-rv5j1201	2055	20	dogs	dog	NNS
cord-022561-rv5j1201	2055	21	and	and	CC
cord-022561-rv5j1201	2055	22	pigs	pig	NNS
cord-022561-rv5j1201	2055	23	are	be	VBP
cord-022561-rv5j1201	2055	24	attached	attach	VBN
cord-022561-rv5j1201	2055	25	loosely	loosely	RB
cord-022561-rv5j1201	2055	26	to	to	IN
cord-022561-rv5j1201	2055	27	the	the	DT
cord-022561-rv5j1201	2055	28	stomach	stomach	NN
cord-022561-rv5j1201	2055	29	by	by	IN
cord-022561-rv5j1201	2055	30	the	the	DT
cord-022561-rv5j1201	2055	31	gastrosplenic	gastrosplenic	NNP
cord-022561-rv5j1201	2055	32	ligament	ligament	NN
cord-022561-rv5j1201	2055	33	.	.	.
cord-022561-rv5j1201	2056	1	It	-PRON-	PRP
cord-022561-rv5j1201	2056	2	is	be	VBZ
cord-022561-rv5j1201	2056	3	the	the	DT
cord-022561-rv5j1201	2056	4	twisting	twisting	NN
cord-022561-rv5j1201	2056	5	of	of	IN
cord-022561-rv5j1201	2056	6	the	the	DT
cord-022561-rv5j1201	2056	7	spleen	spleen	NNS
cord-022561-rv5j1201	2056	8	around	around	IN
cord-022561-rv5j1201	2056	9	this	this	DT
cord-022561-rv5j1201	2056	10	ligament	ligament	NN
cord-022561-rv5j1201	2056	11	that	that	WDT
cord-022561-rv5j1201	2056	12	results	result	VBZ
cord-022561-rv5j1201	2056	13	initially	initially	RB
cord-022561-rv5j1201	2056	14	in	in	IN
cord-022561-rv5j1201	2056	15	occlusion	occlusion	NN
cord-022561-rv5j1201	2056	16	of	of	IN
cord-022561-rv5j1201	2056	17	the	the	DT
cord-022561-rv5j1201	2056	18	veins	vein	NNS
cord-022561-rv5j1201	2056	19	,	,	,
cord-022561-rv5j1201	2056	20	causing	cause	VBG
cord-022561-rv5j1201	2056	21	splenic	splenic	JJ
cord-022561-rv5j1201	2056	22	congestion	congestion	NN
cord-022561-rv5j1201	2056	23	,	,	,
cord-022561-rv5j1201	2056	24	and	and	CC
cord-022561-rv5j1201	2056	25	later	later	RB
cord-022561-rv5j1201	2056	26	in	in	IN
cord-022561-rv5j1201	2056	27	occlusion	occlusion	NN
cord-022561-rv5j1201	2056	28	of	of	IN
cord-022561-rv5j1201	2056	29	the	the	DT
cord-022561-rv5j1201	2056	30	artery	artery	NN
cord-022561-rv5j1201	2056	31	,	,	,
cord-022561-rv5j1201	2056	32	causing	cause	VBG
cord-022561-rv5j1201	2056	33	splenic	splenic	JJ
cord-022561-rv5j1201	2056	34	infarction	infarction	NN
cord-022561-rv5j1201	2056	35	.	.	.
cord-022561-rv5j1201	2057	1	In	in	IN
cord-022561-rv5j1201	2057	2	dogs	dog	NNS
cord-022561-rv5j1201	2057	3	the	the	DT
cord-022561-rv5j1201	2057	4	spleen	spleen	NN
cord-022561-rv5j1201	2057	5	is	be	VBZ
cord-022561-rv5j1201	2057	6	uniformly	uniformly	RB
cord-022561-rv5j1201	2057	7	and	and	CC
cord-022561-rv5j1201	2057	8	markedly	markedly	RB
cord-022561-rv5j1201	2057	9	enlarged	enlarged	JJ
cord-022561-rv5j1201	2057	10	and	and	CC
cord-022561-rv5j1201	2057	11	may	may	MD
cord-022561-rv5j1201	2057	12	be	be	VB
cord-022561-rv5j1201	2057	13	blue	blue	JJ
cord-022561-rv5j1201	2057	14	-	-	HYPH
cord-022561-rv5j1201	2057	15	black	black	JJ
cord-022561-rv5j1201	2057	16	from	from	IN
cord-022561-rv5j1201	2057	17	cyanosis	cyanosis	NN
cord-022561-rv5j1201	2057	18	.	.	.
cord-022561-rv5j1201	2058	1	It	-PRON-	PRP
cord-022561-rv5j1201	2058	2	is	be	VBZ
cord-022561-rv5j1201	2058	3	often	often	RB
cord-022561-rv5j1201	2058	4	folded	fold	VBN
cord-022561-rv5j1201	2058	5	back	back	RB
cord-022561-rv5j1201	2058	6	on	on	IN
cord-022561-rv5j1201	2058	7	itself	-PRON-	PRP
cord-022561-rv5j1201	2058	8	(	(	-LRB-
cord-022561-rv5j1201	2058	9	visceral	visceral	JJ
cord-022561-rv5j1201	2058	10	surface	surface	NN
cord-022561-rv5j1201	2058	11	to	to	IN
cord-022561-rv5j1201	2058	12	visceral	visceral	JJ
cord-022561-rv5j1201	2058	13	surface	surface	NN
cord-022561-rv5j1201	2058	14	)	)	-RRB-
cord-022561-rv5j1201	2058	15	in	in	IN
cord-022561-rv5j1201	2058	16	the	the	DT
cord-022561-rv5j1201	2058	17	shape	shape	NN
cord-022561-rv5j1201	2058	18	of	of	IN
cord-022561-rv5j1201	2058	19	the	the	DT
cord-022561-rv5j1201	2058	20	letter	letter	NN
cord-022561-rv5j1201	2058	21	"	"	``
cord-022561-rv5j1201	2058	22	C.	C.	NNP
cord-022561-rv5j1201	2058	23	"	"	''
cord-022561-rv5j1201	2058	24	Treatment	treatment	NN
cord-022561-rv5j1201	2058	25	for	for	IN
cord-022561-rv5j1201	2058	26	this	this	DT
cord-022561-rv5j1201	2058	27	condition	condition	NN
cord-022561-rv5j1201	2058	28	is	be	VBZ
cord-022561-rv5j1201	2058	29	most	most	RBS
cord-022561-rv5j1201	2058	30	often	often	RB
cord-022561-rv5j1201	2058	31	splenectomy	splenectomy	JJ
cord-022561-rv5j1201	2058	32	.	.	.
cord-022561-rv5j1201	2059	1	Barbiturate	Barbiturate	NNP
cord-022561-rv5j1201	2059	2	Euthanasia	Euthanasia	NNP
cord-022561-rv5j1201	2059	3	,	,	,
cord-022561-rv5j1201	2059	4	Anesthesia	Anesthesia	NNP
cord-022561-rv5j1201	2059	5	,	,	,
cord-022561-rv5j1201	2059	6	or	or	CC
cord-022561-rv5j1201	2059	7	Sedation	sedation	NN
cord-022561-rv5j1201	2059	8	.	.	.
cord-022561-rv5j1201	2060	1	Intravenous	intravenous	JJ
cord-022561-rv5j1201	2060	2	injection	injection	NN
cord-022561-rv5j1201	2060	3	of	of	IN
cord-022561-rv5j1201	2060	4	barbiturates	barbiturate	NNS
cord-022561-rv5j1201	2060	5	induces	induce	VBZ
cord-022561-rv5j1201	2060	6	acute	acute	JJ
cord-022561-rv5j1201	2060	7	passive	passive	JJ
cord-022561-rv5j1201	2060	8	congestion	congestion	NN
cord-022561-rv5j1201	2060	9	in	in	IN
cord-022561-rv5j1201	2060	10	the	the	DT
cord-022561-rv5j1201	2060	11	spleen	spleen	NN
cord-022561-rv5j1201	2060	12	due	due	IN
cord-022561-rv5j1201	2060	13	to	to	IN
cord-022561-rv5j1201	2060	14	relaxation	relaxation	NN
cord-022561-rv5j1201	2060	15	of	of	IN
cord-022561-rv5j1201	2060	16	smooth	smooth	JJ
cord-022561-rv5j1201	2060	17	muscle	muscle	NN
cord-022561-rv5j1201	2060	18	in	in	IN
cord-022561-rv5j1201	2060	19	the	the	DT
cord-022561-rv5j1201	2060	20	capsule	capsule	NN
cord-022561-rv5j1201	2060	21	and	and	CC
cord-022561-rv5j1201	2060	22	trabeculae	trabeculae	NNP
cord-022561-rv5j1201	2060	23	.	.	.
cord-022561-rv5j1201	2061	1	This	this	DT
cord-022561-rv5j1201	2061	2	phenomenon	phenomenon	NN
cord-022561-rv5j1201	2061	3	is	be	VBZ
cord-022561-rv5j1201	2061	4	seen	see	VBN
cord-022561-rv5j1201	2061	5	most	most	RBS
cord-022561-rv5j1201	2061	6	dramatically	dramatically	RB
cord-022561-rv5j1201	2061	7	at	at	IN
cord-022561-rv5j1201	2061	8	autopsy	autopsy	JJ
cord-022561-rv5j1201	2061	9	only	only	JJ
cord-022561-rv5j1201	2061	10	histologic	histologic	JJ
cord-022561-rv5j1201	2061	11	lesion	lesion	NN
cord-022561-rv5j1201	2061	12	may	may	MD
cord-022561-rv5j1201	2061	13	be	be	VB
cord-022561-rv5j1201	2061	14	marked	mark	VBN
cord-022561-rv5j1201	2061	15	congestion	congestion	NN
cord-022561-rv5j1201	2061	16	of	of	IN
cord-022561-rv5j1201	2061	17	the	the	DT
cord-022561-rv5j1201	2061	18	marginal	marginal	JJ
cord-022561-rv5j1201	2061	19	sinuses	sinus	NNS
cord-022561-rv5j1201	2061	20	and	and	CC
cord-022561-rv5j1201	2061	21	the	the	DT
cord-022561-rv5j1201	2061	22	splenic	splenic	JJ
cord-022561-rv5j1201	2061	23	red	red	JJ
cord-022561-rv5j1201	2061	24	pulp	pulp	NN
cord-022561-rv5j1201	2061	25	vascular	vascular	JJ
cord-022561-rv5j1201	2061	26	spaces	space	NNS
cord-022561-rv5j1201	2061	27	.	.	.
cord-022561-rv5j1201	2062	1	At	at	IN
cord-022561-rv5j1201	2062	2	low	low	JJ
cord-022561-rv5j1201	2062	3	magnification	magnification	NN
cord-022561-rv5j1201	2062	4	,	,	,
cord-022561-rv5j1201	2062	5	congestion	congestion	NN
cord-022561-rv5j1201	2062	6	of	of	IN
cord-022561-rv5j1201	2062	7	the	the	DT
cord-022561-rv5j1201	2062	8	marginal	marginal	JJ
cord-022561-rv5j1201	2062	9	sinus	sinus	NN
cord-022561-rv5j1201	2062	10	may	may	MD
cord-022561-rv5j1201	2062	11	appear	appear	VB
cord-022561-rv5j1201	2062	12	as	as	IN
cord-022561-rv5j1201	2062	13	a	a	DT
cord-022561-rv5j1201	2062	14	circumferential	circumferential	JJ
cord-022561-rv5j1201	2062	15	red	red	JJ
cord-022561-rv5j1201	2062	16	ring	ring	NN
cord-022561-rv5j1201	2062	17	around	around	IN
cord-022561-rv5j1201	2062	18	the	the	DT
cord-022561-rv5j1201	2062	19	splenic	splenic	JJ
cord-022561-rv5j1201	2062	20	follicle	follicle	NN
cord-022561-rv5j1201	2062	21	,	,	,
cord-022561-rv5j1201	2062	22	and	and	CC
cord-022561-rv5j1201	2062	23	there	there	EX
cord-022561-rv5j1201	2062	24	is	be	VBZ
cord-022561-rv5j1201	2062	25	marked	mark	VBN
cord-022561-rv5j1201	2062	26	lymphocytolysis	lymphocytolysis	NN
cord-022561-rv5j1201	2062	27	of	of	IN
cord-022561-rv5j1201	2062	28	follicles	follicle	NNS
cord-022561-rv5j1201	2062	29	and	and	CC
cord-022561-rv5j1201	2062	30	PALS	pals	NN
cord-022561-rv5j1201	2062	31	.	.	.
cord-022561-rv5j1201	2063	1	Intravascular	Intravascular	VBN
cord-022561-rv5j1201	2063	2	free	free	JJ
cord-022561-rv5j1201	2063	3	bacilli	bacillus	NNS
cord-022561-rv5j1201	2063	4	are	be	VBP
cord-022561-rv5j1201	2063	5	noted	note	VBN
cord-022561-rv5j1201	2063	6	and	and	CC
cord-022561-rv5j1201	2063	7	may	may	MD
cord-022561-rv5j1201	2063	8	be	be	VB
cord-022561-rv5j1201	2063	9	seen	see	VBN
cord-022561-rv5j1201	2063	10	in	in	IN
cord-022561-rv5j1201	2063	11	impression	impression	NN
cord-022561-rv5j1201	2063	12	smears	smear	NNS
cord-022561-rv5j1201	2063	13	of	of	IN
cord-022561-rv5j1201	2063	14	peripheral	peripheral	JJ
cord-022561-rv5j1201	2063	15	blood	blood	NN
cord-022561-rv5j1201	2063	16	,	,	,
cord-022561-rv5j1201	2063	17	presumably	presumably	RB
cord-022561-rv5j1201	2063	18	because	because	IN
cord-022561-rv5j1201	2063	19	death	death	NN
cord-022561-rv5j1201	2063	20	is	be	VBZ
cord-022561-rv5j1201	2063	21	so	so	RB
cord-022561-rv5j1201	2063	22	rapid	rapid	JJ
cord-022561-rv5j1201	2063	23	from	from	IN
cord-022561-rv5j1201	2063	24	the	the	DT
cord-022561-rv5j1201	2063	25	anthrax	anthrax	NN
cord-022561-rv5j1201	2063	26	toxin	toxin	NN
cord-022561-rv5j1201	2063	27	that	that	IN
cord-022561-rv5j1201	2063	28	there	there	EX
cord-022561-rv5j1201	2063	29	is	be	VBZ
cord-022561-rv5j1201	2063	30	insufficient	insufficient	JJ
cord-022561-rv5j1201	2063	31	time	time	NN
cord-022561-rv5j1201	2063	32	for	for	IN
cord-022561-rv5j1201	2063	33	phagocytosis	phagocytosis	NN
cord-022561-rv5j1201	2063	34	to	to	TO
cord-022561-rv5j1201	2063	35	take	take	VB
cord-022561-rv5j1201	2063	36	place	place	NN
cord-022561-rv5j1201	2063	37	.	.	.
cord-022561-rv5j1201	2064	1	If	if	IN
cord-022561-rv5j1201	2064	2	the	the	DT
cord-022561-rv5j1201	2064	3	animal	animal	NN
cord-022561-rv5j1201	2064	4	lives	live	VBZ
cord-022561-rv5j1201	2064	5	longer	long	RBR
cord-022561-rv5j1201	2064	6	,	,	,
cord-022561-rv5j1201	2064	7	scattered	scatter	VBN
cord-022561-rv5j1201	2064	8	neutrophils	neutrophil	NNS
cord-022561-rv5j1201	2064	9	are	be	VBP
cord-022561-rv5j1201	2064	10	present	present	JJ
cord-022561-rv5j1201	2064	11	in	in	IN
cord-022561-rv5j1201	2064	12	the	the	DT
cord-022561-rv5j1201	2064	13	marginal	marginal	JJ
cord-022561-rv5j1201	2064	14	sinuses	sinus	NNS
cord-022561-rv5j1201	2064	15	and	and	CC
cord-022561-rv5j1201	2064	16	red	red	JJ
cord-022561-rv5j1201	2064	17	pulp	pulp	NN
cord-022561-rv5j1201	2064	18	vascular	vascular	JJ
cord-022561-rv5j1201	2064	19	spaces	space	NNS
cord-022561-rv5j1201	2064	20	(	(	-LRB-
cord-022561-rv5j1201	2064	21	Fig	Fig	NNP
cord-022561-rv5j1201	2064	22	.	.	.
cord-022561-rv5j1201	2064	23	13	13	CD
cord-022561-rv5j1201	2064	24	-	-	SYM
cord-022561-rv5j1201	2064	25	57	57	CD
cord-022561-rv5j1201	2064	26	)	)	-RRB-
cord-022561-rv5j1201	2064	27	.	.	.
cord-022561-rv5j1201	2065	1	Anthrax	anthrax	NN
cord-022561-rv5j1201	2065	2	cases	case	NNS
cord-022561-rv5j1201	2065	3	are	be	VBP
cord-022561-rv5j1201	2065	4	not	not	RB
cord-022561-rv5j1201	2065	5	normally	normally	RB
cord-022561-rv5j1201	2065	6	autopsied	autopsie	VBN
cord-022561-rv5j1201	2065	7	because	because	IN
cord-022561-rv5j1201	2065	8	exposure	exposure	NN
cord-022561-rv5j1201	2065	9	to	to	IN
cord-022561-rv5j1201	2065	10	air	air	NN
cord-022561-rv5j1201	2065	11	causes	cause	NNS
cord-022561-rv5j1201	2065	12	the	the	DT
cord-022561-rv5j1201	2065	13	bacteria	bacteria	NNS
cord-022561-rv5j1201	2065	14	to	to	TO
cord-022561-rv5j1201	2065	15	sporulate	sporulate	VB
cord-022561-rv5j1201	2065	16	-	-	HYPH
cord-022561-rv5j1201	2065	17	anthrax	anthrax	NN
cord-022561-rv5j1201	2065	18	spores	spore	NNS
cord-022561-rv5j1201	2065	19	are	be	VBP
cord-022561-rv5j1201	2065	20	extremely	extremely	RB
cord-022561-rv5j1201	2065	21	resistant	resistant	JJ
cord-022561-rv5j1201	2065	22	and	and	CC
cord-022561-rv5j1201	2065	23	readily	readily	RB
cord-022561-rv5j1201	2065	24	contaminate	contaminate	VB
cord-022561-rv5j1201	2065	25	the	the	DT
cord-022561-rv5j1201	2065	26	environment	environment	NN
cord-022561-rv5j1201	2065	27	.	.	.
cord-022561-rv5j1201	2066	1	Acute	acute	JJ
cord-022561-rv5j1201	2066	2	Hemolytic	hemolytic	JJ
cord-022561-rv5j1201	2066	3	Anemias	Anemias	NNPS
cord-022561-rv5j1201	2066	4	.	.	.
cord-022561-rv5j1201	2067	1	Hemolytic	hemolytic	JJ
cord-022561-rv5j1201	2067	2	diseases	disease	NNS
cord-022561-rv5j1201	2067	3	,	,	,
cord-022561-rv5j1201	2067	4	including	include	VBG
cord-022561-rv5j1201	2067	5	acute	acute	JJ
cord-022561-rv5j1201	2067	6	babesiosis	babesiosis	NN
cord-022561-rv5j1201	2067	7	,	,	,
cord-022561-rv5j1201	2067	8	hemolytic	hemolytic	JJ
cord-022561-rv5j1201	2067	9	crises	crisis	NNS
cord-022561-rv5j1201	2067	10	in	in	IN
cord-022561-rv5j1201	2067	11	equine	equine	JJ
cord-022561-rv5j1201	2067	12	infectious	infectious	JJ
cord-022561-rv5j1201	2067	13	anemia	anemia	NN
cord-022561-rv5j1201	2067	14	,	,	,
cord-022561-rv5j1201	2067	15	and	and	CC
cord-022561-rv5j1201	2067	16	immune	immune	NN
cord-022561-rv5j1201	2067	17	-	-	HYPH
cord-022561-rv5j1201	2067	18	mediated	mediate	VBN
cord-022561-rv5j1201	2067	19	hemolytic	hemolytic	JJ
cord-022561-rv5j1201	2067	20	anemia	anemia	NN
cord-022561-rv5j1201	2067	21	,	,	,
cord-022561-rv5j1201	2067	22	can	can	MD
cord-022561-rv5j1201	2067	23	cause	cause	VB
cord-022561-rv5j1201	2067	24	marked	mark	VBN
cord-022561-rv5j1201	2067	25	splenic	splenic	JJ
cord-022561-rv5j1201	2067	26	congestion	congestion	NN
cord-022561-rv5j1201	2067	27	.	.	.
cord-022561-rv5j1201	2068	1	The	the	DT
cord-022561-rv5j1201	2068	2	splenic	splenic	JJ
cord-022561-rv5j1201	2068	3	congestion	congestion	NN
cord-022561-rv5j1201	2068	4	is	be	VBZ
cord-022561-rv5j1201	2068	5	due	due	JJ
cord-022561-rv5j1201	2068	6	to	to	IN
cord-022561-rv5j1201	2068	7	the	the	DT
cord-022561-rv5j1201	2068	8	process	process	NN
cord-022561-rv5j1201	2068	9	of	of	IN
cord-022561-rv5j1201	2068	10	removal	removal	NN
cord-022561-rv5j1201	2068	11	(	(	-LRB-
cord-022561-rv5j1201	2068	12	phagocytosis	phagocytosis	NN
cord-022561-rv5j1201	2068	13	)	)	-RRB-
cord-022561-rv5j1201	2068	14	and	and	CC
cord-022561-rv5j1201	2068	15	storage	storage	NN
cord-022561-rv5j1201	2068	16	of	of	IN
cord-022561-rv5j1201	2068	17	large	large	JJ
cord-022561-rv5j1201	2068	18	numbers	number	NNS
cord-022561-rv5j1201	2068	19	of	of	IN
cord-022561-rv5j1201	2068	20	sequestered	sequester	VBN
cord-022561-rv5j1201	2068	21	parasitized	parasitize	VBN
cord-022561-rv5j1201	2068	22	and/or	and/or	CC
cord-022561-rv5j1201	2068	23	altered	altered	JJ
cord-022561-rv5j1201	2068	24	erythrocytes	erythrocyte	NNS
cord-022561-rv5j1201	2068	25	from	from	IN
cord-022561-rv5j1201	2068	26	the	the	DT
cord-022561-rv5j1201	2068	27	circulation	circulation	NN
cord-022561-rv5j1201	2068	28	.	.	.
cord-022561-rv5j1201	2069	1	Histologically	histologically	RB
cord-022561-rv5j1201	2069	2	,	,	,
cord-022561-rv5j1201	2069	3	there	there	EX
cord-022561-rv5j1201	2069	4	is	be	VBZ
cord-022561-rv5j1201	2069	5	dilation	dilation	NN
cord-022561-rv5j1201	2069	6	of	of	IN
cord-022561-rv5j1201	2069	7	the	the	DT
cord-022561-rv5j1201	2069	8	red	red	JJ
cord-022561-rv5j1201	2069	9	pulp	pulp	NN
cord-022561-rv5j1201	2069	10	vascular	vascular	JJ
cord-022561-rv5j1201	2069	11	spaces	space	NNS
cord-022561-rv5j1201	2069	12	with	with	IN
cord-022561-rv5j1201	2069	13	erythrocytes	erythrocyte	NNS
cord-022561-rv5j1201	2069	14	and	and	CC
cord-022561-rv5j1201	2069	15	erythrophagocytes	erythrophagocyte	NNS
cord-022561-rv5j1201	2069	16	.	.	.
cord-022561-rv5j1201	2070	1	With	with	IN
cord-022561-rv5j1201	2070	2	chronicity	chronicity	NN
cord-022561-rv5j1201	2070	3	there	there	EX
cord-022561-rv5j1201	2070	4	is	be	VBZ
cord-022561-rv5j1201	2070	5	hyperplasia	hyperplasia	NN
cord-022561-rv5j1201	2070	6	of	of	IN
cord-022561-rv5j1201	2070	7	the	the	DT
cord-022561-rv5j1201	2070	8	red	red	JJ
cord-022561-rv5j1201	2070	9	pulp	pulp	NN
cord-022561-rv5j1201	2070	10	macrophages	macrophage	NNS
cord-022561-rv5j1201	2070	11	,	,	,
cord-022561-rv5j1201	2070	12	hemosiderosis	hemosiderosis	NN
cord-022561-rv5j1201	2070	13	,	,	,
cord-022561-rv5j1201	2070	14	and	and	CC
cord-022561-rv5j1201	2070	15	reduced	reduce	VBN
cord-022561-rv5j1201	2070	16	congestion	congestion	NN
cord-022561-rv5j1201	2070	17	because	because	IN
cord-022561-rv5j1201	2070	18	the	the	DT
cord-022561-rv5j1201	2070	19	number	number	NN
cord-022561-rv5j1201	2070	20	of	of	IN
cord-022561-rv5j1201	2070	21	sequestered	sequester	VBN
cord-022561-rv5j1201	2070	22	diseased	diseased	JJ
cord-022561-rv5j1201	2070	23	erythrocytes	erythrocyte	NNS
cord-022561-rv5j1201	2070	24	is	be	VBZ
cord-022561-rv5j1201	2070	25	diminished	diminish	VBN
cord-022561-rv5j1201	2070	26	.	.	.
cord-022561-rv5j1201	2071	1	Spleen	spleen	NN
cord-022561-rv5j1201	2071	2	.	.	.
cord-022561-rv5j1201	2072	1	The	the	DT
cord-022561-rv5j1201	2072	2	three	three	CD
cord-022561-rv5j1201	2072	3	general	general	JJ
cord-022561-rv5j1201	2072	4	categories	category	NNS
cord-022561-rv5j1201	2072	5	of	of	IN
cord-022561-rv5j1201	2072	6	conditions	condition	NNS
cord-022561-rv5j1201	2072	7	leading	lead	VBG
cord-022561-rv5j1201	2072	8	to	to	IN
cord-022561-rv5j1201	2072	9	uniform	uniform	JJ
cord-022561-rv5j1201	2072	10	splenomegaly	splenomegaly	NN
cord-022561-rv5j1201	2072	11	with	with	IN
cord-022561-rv5j1201	2072	12	a	a	DT
cord-022561-rv5j1201	2072	13	firm	firm	JJ
cord-022561-rv5j1201	2072	14	meaty	meaty	JJ
cord-022561-rv5j1201	2072	15	consistency	consistency	NN
cord-022561-rv5j1201	2072	16	are	be	VBP
cord-022561-rv5j1201	2072	17	(	(	-LRB-
cord-022561-rv5j1201	2072	18	1	1	LS
cord-022561-rv5j1201	2072	19	)	)	-RRB-
cord-022561-rv5j1201	2072	20	marked	mark	VBN
cord-022561-rv5j1201	2072	21	phagocytosis	phagocytosis	NN
cord-022561-rv5j1201	2072	22	of	of	IN
cord-022561-rv5j1201	2072	23	cells	cell	NNS
cord-022561-rv5j1201	2072	24	,	,	,
cord-022561-rv5j1201	2072	25	debris	debris	NN
cord-022561-rv5j1201	2072	26	,	,	,
cord-022561-rv5j1201	2072	27	or	or	CC
cord-022561-rv5j1201	2072	28	foreign	foreign	JJ
cord-022561-rv5j1201	2072	29	agents	agent	NNS
cord-022561-rv5j1201	2072	30	/	/	SYM
cord-022561-rv5j1201	2072	31	material	material	NN
cord-022561-rv5j1201	2072	32	;	;	:
cord-022561-rv5j1201	2072	33	(	(	-LRB-
cord-022561-rv5j1201	2072	34	2	2	LS
cord-022561-rv5j1201	2072	35	)	)	-RRB-
cord-022561-rv5j1201	2072	36	proliferation	proliferation	NN
cord-022561-rv5j1201	2072	37	or	or	CC
cord-022561-rv5j1201	2072	38	infiltration	infiltration	NN
cord-022561-rv5j1201	2072	39	of	of	IN
cord-022561-rv5j1201	2072	40	cells	cell	NNS
cord-022561-rv5j1201	2072	41	as	as	IN
cord-022561-rv5j1201	2072	42	occurs	occur	NNS
cord-022561-rv5j1201	2072	43	in	in	IN
cord-022561-rv5j1201	2072	44	diffuse	diffuse	JJ
cord-022561-rv5j1201	2072	45	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	2072	46	and	and	CC
cord-022561-rv5j1201	2072	47	histiocytic	histiocytic	JJ
cord-022561-rv5j1201	2072	48	hyperplasia	hyperplasia	NN
cord-022561-rv5j1201	2072	49	,	,	,
cord-022561-rv5j1201	2072	50	diffuse	diffuse	VB
cord-022561-rv5j1201	2072	51	granulomatous	granulomatous	JJ
cord-022561-rv5j1201	2072	52	disease	disease	NN
cord-022561-rv5j1201	2073	1	(	(	-LRB-
cord-022561-rv5j1201	2073	2	E	E	NNP
cord-022561-rv5j1201	2073	3	-Table	-table	JJ
cord-022561-rv5j1201	2073	4	13	13	CD
cord-022561-rv5j1201	2073	5	-2	-2	CD
cord-022561-rv5j1201	2073	6	)	)	-RRB-
cord-022561-rv5j1201	2073	7	,	,	,
cord-022561-rv5j1201	2073	8	EMH	EMH	NNP
cord-022561-rv5j1201	2073	9	,	,	,
cord-022561-rv5j1201	2073	10	and	and	CC
cord-022561-rv5j1201	2073	11	neoplasia	neoplasia	NN
cord-022561-rv5j1201	2073	12	;	;	,
cord-022561-rv5j1201	2073	13	(	(	-LRB-
cord-022561-rv5j1201	2073	14	3	3	CD
cord-022561-rv5j1201	2073	15	)	)	-RRB-
cord-022561-rv5j1201	2073	16	storage	storage	NN
cord-022561-rv5j1201	2073	17	of	of	IN
cord-022561-rv5j1201	2073	18	materials	material	NNS
cord-022561-rv5j1201	2073	19	in	in	IN
cord-022561-rv5j1201	2073	20	storage	storage	NN
cord-022561-rv5j1201	2073	21	diseases	disease	NNS
cord-022561-rv5j1201	2073	22	or	or	CC
cord-022561-rv5j1201	2073	23	amyloidosis	amyloidosis	NN
cord-022561-rv5j1201	2073	24	.	.	.
cord-022561-rv5j1201	2074	1	It	-PRON-	PRP
cord-022561-rv5j1201	2074	2	is	be	VBZ
cord-022561-rv5j1201	2074	3	important	important	JJ
cord-022561-rv5j1201	2074	4	to	to	TO
cord-022561-rv5j1201	2074	5	recognize	recognize	VB
cord-022561-rv5j1201	2074	6	that	that	IN
cord-022561-rv5j1201	2074	7	more	more	JJR
cord-022561-rv5j1201	2074	8	than	than	IN
cord-022561-rv5j1201	2074	9	one	one	CD
cord-022561-rv5j1201	2074	10	of	of	IN
cord-022561-rv5j1201	2074	11	these	these	DT
cord-022561-rv5j1201	2074	12	processes	process	NNS
cord-022561-rv5j1201	2074	13	can	can	MD
cord-022561-rv5j1201	2074	14	occur	occur	VB
cord-022561-rv5j1201	2074	15	in	in	IN
cord-022561-rv5j1201	2074	16	the	the	DT
cord-022561-rv5j1201	2074	17	same	same	JJ
cord-022561-rv5j1201	2074	18	patient	patient	NN
cord-022561-rv5j1201	2074	19	(	(	-LRB-
cord-022561-rv5j1201	2074	20	e.g.	e.g.	RB
cord-022561-rv5j1201	2074	21	,	,	,
cord-022561-rv5j1201	2074	22	dogs	dog	NNS
cord-022561-rv5j1201	2074	23	with	with	IN
cord-022561-rv5j1201	2074	24	immunemediated	immunemediated	JJ
cord-022561-rv5j1201	2074	25	hemolytic	hemolytic	JJ
cord-022561-rv5j1201	2074	26	anemia	anemia	NN
cord-022561-rv5j1201	2074	27	may	may	MD
cord-022561-rv5j1201	2074	28	have	have	VB
cord-022561-rv5j1201	2074	29	both	both	DT
cord-022561-rv5j1201	2074	30	marked	mark	VBN
cord-022561-rv5j1201	2074	31	erythrophagocytosis	erythrophagocytosis	NN
cord-022561-rv5j1201	2074	32	and	and	CC
cord-022561-rv5j1201	2074	33	EMH	EMH	NNP
cord-022561-rv5j1201	2074	34	)	)	-RRB-
cord-022561-rv5j1201	2074	35	.	.	.
cord-022561-rv5j1201	2075	1	The	the	DT
cord-022561-rv5j1201	2075	2	appearance	appearance	NN
cord-022561-rv5j1201	2075	3	of	of	IN
cord-022561-rv5j1201	2075	4	the	the	DT
cord-022561-rv5j1201	2075	5	cut	cut	NN
cord-022561-rv5j1201	2075	6	surface	surface	NN
cord-022561-rv5j1201	2075	7	of	of	IN
cord-022561-rv5j1201	2075	8	a	a	DT
cord-022561-rv5j1201	2075	9	meaty	meaty	JJ
cord-022561-rv5j1201	2075	10	spleen	spleen	NN
cord-022561-rv5j1201	2075	11	depends	depend	VBZ
cord-022561-rv5j1201	2075	12	on	on	IN
cord-022561-rv5j1201	2075	13	the	the	DT
cord-022561-rv5j1201	2075	14	underlying	underlying	JJ
cord-022561-rv5j1201	2075	15	cause	cause	NN
cord-022561-rv5j1201	2075	16	.	.	.
cord-022561-rv5j1201	2076	1	In	in	IN
cord-022561-rv5j1201	2076	2	diffuse	diffuse	JJ
cord-022561-rv5j1201	2076	3	marked	marked	JJ
cord-022561-rv5j1201	2076	4	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	2076	5	hyperplasia	hyperplasia	NN
cord-022561-rv5j1201	2076	6	,	,	,
cord-022561-rv5j1201	2076	7	large	large	JJ
cord-022561-rv5j1201	2076	8	,	,	,
cord-022561-rv5j1201	2076	9	disseminated	disseminate	VBN
cord-022561-rv5j1201	2076	10	,	,	,
cord-022561-rv5j1201	2076	11	discrete	discrete	JJ
cord-022561-rv5j1201	2076	12	,	,	,
cord-022561-rv5j1201	2076	13	white	white	JJ
cord-022561-rv5j1201	2076	14	,	,	,
cord-022561-rv5j1201	2076	15	bulging	bulge	VBG
cord-022561-rv5j1201	2076	16	nodules	nodule	NNS
cord-022561-rv5j1201	2076	17	are	be	VBP
cord-022561-rv5j1201	2076	18	visible	visible	JJ
cord-022561-rv5j1201	2076	19	.	.	.
cord-022561-rv5j1201	2077	1	Spleens	spleen	NNS
cord-022561-rv5j1201	2077	2	with	with	IN
cord-022561-rv5j1201	2077	3	diffuse	diffuse	JJ
cord-022561-rv5j1201	2077	4	infiltrative	infiltrative	JJ
cord-022561-rv5j1201	2077	5	neoplasms	neoplasm	NNS
cord-022561-rv5j1201	2077	6	,	,	,
cord-022561-rv5j1201	2077	7	such	such	JJ
cord-022561-rv5j1201	2077	8	as	as	IN
cord-022561-rv5j1201	2077	9	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2077	10	,	,	,
cord-022561-rv5j1201	2077	11	are	be	VBP
cord-022561-rv5j1201	2077	12	pink	pink	JJ
cord-022561-rv5j1201	2077	13	-	-	HYPH
cord-022561-rv5j1201	2077	14	light	light	NN
cord-022561-rv5j1201	2077	15	purple	purple	NN
cord-022561-rv5j1201	2077	16	on	on	IN
cord-022561-rv5j1201	2077	17	cut	cut	NN
cord-022561-rv5j1201	2077	18	surface	surface	NN
cord-022561-rv5j1201	2077	19	.	.	.
cord-022561-rv5j1201	2078	1	Diffuse	diffuse	VB
cord-022561-rv5j1201	2078	2	Lymphoid	lymphoid	JJ
cord-022561-rv5j1201	2078	3	Hyperplasia	hyperplasia	NN
cord-022561-rv5j1201	2078	4	.	.	.
cord-022561-rv5j1201	2079	1	Lymphoid	lymphoid	JJ
cord-022561-rv5j1201	2079	2	hyperplasia	hyperplasia	NN
cord-022561-rv5j1201	2079	3	has	have	VBZ
cord-022561-rv5j1201	2079	4	been	be	VBN
cord-022561-rv5j1201	2079	5	described	describe	VBN
cord-022561-rv5j1201	2079	6	in	in	IN
cord-022561-rv5j1201	2079	7	detail	detail	NN
cord-022561-rv5j1201	2079	8	in	in	IN
cord-022561-rv5j1201	2079	9	the	the	DT
cord-022561-rv5j1201	2079	10	section	section	NN
cord-022561-rv5j1201	2079	11	on	on	IN
cord-022561-rv5j1201	2079	12	Dysfunction	Dysfunction	NNP
cord-022561-rv5j1201	2079	13	/	/	SYM
cord-022561-rv5j1201	2079	14	Responses	response	NNS
cord-022561-rv5j1201	2079	15	to	to	IN
cord-022561-rv5j1201	2079	16	Injury	injury	NN
cord-022561-rv5j1201	2079	17	.	.	.
cord-022561-rv5j1201	2080	1	In	in	IN
cord-022561-rv5j1201	2080	2	cases	case	NNS
cord-022561-rv5j1201	2080	3	of	of	IN
cord-022561-rv5j1201	2080	4	prolonged	prolonged	JJ
cord-022561-rv5j1201	2080	5	antigenic	antigenic	JJ
cord-022561-rv5j1201	2080	6	stimulation	stimulation	NN
cord-022561-rv5j1201	2080	7	the	the	DT
cord-022561-rv5j1201	2080	8	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	2080	9	salmonellosis	salmonellosis	NN
cord-022561-rv5j1201	2080	10	,	,	,
cord-022561-rv5j1201	2080	11	there	there	EX
cord-022561-rv5j1201	2080	12	may	may	MD
cord-022561-rv5j1201	2080	13	be	be	VB
cord-022561-rv5j1201	2080	14	sufficient	sufficient	JJ
cord-022561-rv5j1201	2080	15	time	time	NN
cord-022561-rv5j1201	2080	16	for	for	IN
cord-022561-rv5j1201	2080	17	neutrophils	neutrophil	NNS
cord-022561-rv5j1201	2080	18	and	and	CC
cord-022561-rv5j1201	2080	19	macrophages	macrophage	NNS
cord-022561-rv5j1201	2080	20	to	to	TO
cord-022561-rv5j1201	2080	21	accumulate	accumulate	VB
cord-022561-rv5j1201	2080	22	in	in	IN
cord-022561-rv5j1201	2080	23	the	the	DT
cord-022561-rv5j1201	2080	24	marginal	marginal	JJ
cord-022561-rv5j1201	2080	25	sinuses	sinus	NNS
cord-022561-rv5j1201	2080	26	,	,	,
cord-022561-rv5j1201	2080	27	marginal	marginal	JJ
cord-022561-rv5j1201	2080	28	zones	zone	NNS
cord-022561-rv5j1201	2080	29	,	,	,
cord-022561-rv5j1201	2080	30	and	and	CC
cord-022561-rv5j1201	2080	31	splenic	splenic	JJ
cord-022561-rv5j1201	2080	32	red	red	JJ
cord-022561-rv5j1201	2080	33	pulp	pulp	NN
cord-022561-rv5j1201	2080	34	vascular	vascular	JJ
cord-022561-rv5j1201	2080	35	spaces	space	NNS
cord-022561-rv5j1201	2080	36	.	.	.
cord-022561-rv5j1201	2081	1	Anthrax	Anthrax	NNP
cord-022561-rv5j1201	2081	2	.	.	.
cord-022561-rv5j1201	2082	1	B.	B.	NNP
cord-022561-rv5j1201	2082	2	anthracis	anthracis	NN
cord-022561-rv5j1201	2082	3	,	,	,
cord-022561-rv5j1201	2082	4	the	the	DT
cord-022561-rv5j1201	2082	5	causative	causative	JJ
cord-022561-rv5j1201	2082	6	agent	agent	NN
cord-022561-rv5j1201	2082	7	of	of	IN
cord-022561-rv5j1201	2082	8	anthrax	anthrax	NN
cord-022561-rv5j1201	2082	9	,	,	,
cord-022561-rv5j1201	2082	10	is	be	VBZ
cord-022561-rv5j1201	2082	11	a	a	DT
cord-022561-rv5j1201	2082	12	Grampositive	Grampositive	NNP
cord-022561-rv5j1201	2082	13	,	,	,
cord-022561-rv5j1201	2082	14	large	large	JJ
cord-022561-rv5j1201	2082	15	,	,	,
cord-022561-rv5j1201	2082	16	endospore	endospore	RB
cord-022561-rv5j1201	2082	17	-	-	HYPH
cord-022561-rv5j1201	2082	18	forming	form	VBG
cord-022561-rv5j1201	2082	19	bacillus	bacillus	NN
cord-022561-rv5j1201	2082	20	,	,	,
cord-022561-rv5j1201	2082	21	which	which	WDT
cord-022561-rv5j1201	2082	22	grows	grow	VBZ
cord-022561-rv5j1201	2082	23	in	in	IN
cord-022561-rv5j1201	2082	24	aerobic	aerobic	NN
cord-022561-rv5j1201	2082	25	to	to	IN
cord-022561-rv5j1201	2082	26	facultative	facultative	JJ
cord-022561-rv5j1201	2082	27	anaerobic	anaerobic	JJ
cord-022561-rv5j1201	2082	28	environments	environment	NNS
cord-022561-rv5j1201	2082	29	.	.	.
cord-022561-rv5j1201	2083	1	Anthrax	Anthrax	NNP
cord-022561-rv5j1201	2083	2	is	be	VBZ
cord-022561-rv5j1201	2083	3	primarily	primarily	RB
cord-022561-rv5j1201	2083	4	a	a	DT
cord-022561-rv5j1201	2083	5	disease	disease	NN
cord-022561-rv5j1201	2083	6	of	of	IN
cord-022561-rv5j1201	2083	7	ruminants	ruminant	NNS
cord-022561-rv5j1201	2083	8	,	,	,
cord-022561-rv5j1201	2083	9	especially	especially	RB
cord-022561-rv5j1201	2083	10	cattle	cattle	NNS
cord-022561-rv5j1201	2083	11	and	and	CC
cord-022561-rv5j1201	2083	12	sheep	sheep	NNS
cord-022561-rv5j1201	2083	13	(	(	-LRB-
cord-022561-rv5j1201	2083	14	see	see	VB
cord-022561-rv5j1201	2083	15	Chapters	Chapters	NNPS
cord-022561-rv5j1201	2083	16	4	4	CD
cord-022561-rv5j1201	2083	17	,	,	,
cord-022561-rv5j1201	2083	18	7	7	CD
cord-022561-rv5j1201	2083	19	,	,	,
cord-022561-rv5j1201	2083	20	9	9	CD
cord-022561-rv5j1201	2083	21	,	,	,
cord-022561-rv5j1201	2083	22	and	and	CC
cord-022561-rv5j1201	2083	23	10	10	CD
cord-022561-rv5j1201	2083	24	)	)	-RRB-
cord-022561-rv5j1201	2083	25	.	.	.
cord-022561-rv5j1201	2084	1	Once	once	IN
cord-022561-rv5j1201	2084	2	the	the	DT
cord-022561-rv5j1201	2084	3	spores	spore	NNS
cord-022561-rv5j1201	2084	4	are	be	VBP
cord-022561-rv5j1201	2084	5	ingested	ingest	VBN
cord-022561-rv5j1201	2084	6	,	,	,
cord-022561-rv5j1201	2084	7	they	-PRON-	PRP
cord-022561-rv5j1201	2084	8	replicate	replicate	VBP
cord-022561-rv5j1201	2084	9	locally	locally	RB
cord-022561-rv5j1201	2084	10	in	in	IN
cord-022561-rv5j1201	2084	11	the	the	DT
cord-022561-rv5j1201	2084	12	intestinal	intestinal	JJ
cord-022561-rv5j1201	2084	13	tract	tract	NN
cord-022561-rv5j1201	2084	14	,	,	,
cord-022561-rv5j1201	2084	15	spread	spread	VBN
cord-022561-rv5j1201	2084	16	to	to	IN
cord-022561-rv5j1201	2084	17	regional	regional	JJ
cord-022561-rv5j1201	2084	18	lymph	lymph	NN
cord-022561-rv5j1201	2084	19	nodes	node	NNS
cord-022561-rv5j1201	2084	20	,	,	,
cord-022561-rv5j1201	2084	21	and	and	CC
cord-022561-rv5j1201	2084	22	then	then	RB
cord-022561-rv5j1201	2084	23	disseminate	disseminate	VB
cord-022561-rv5j1201	2084	24	systemically	systemically	RB
cord-022561-rv5j1201	2084	25	through	through	IN
cord-022561-rv5j1201	2084	26	the	the	DT
cord-022561-rv5j1201	2084	27	bloodstream	bloodstream	NN
cord-022561-rv5j1201	2084	28	,	,	,
cord-022561-rv5j1201	2084	29	resulting	result	VBG
cord-022561-rv5j1201	2084	30	in	in	IN
cord-022561-rv5j1201	2084	31	septicemia	septicemia	NN
cord-022561-rv5j1201	2084	32	.	.	.
cord-022561-rv5j1201	2085	1	B.	B.	NNP
cord-022561-rv5j1201	2085	2	anthracis	anthracis	NN
cord-022561-rv5j1201	2085	3	produces	produce	VBZ
cord-022561-rv5j1201	2085	4	exotoxins	exotoxin	NNS
cord-022561-rv5j1201	2085	5	,	,	,
cord-022561-rv5j1201	2085	6	which	which	WDT
cord-022561-rv5j1201	2085	7	degrade	degrade	VBP
cord-022561-rv5j1201	2085	8	endothelial	endothelial	JJ
cord-022561-rv5j1201	2085	9	cell	cell	NN
cord-022561-rv5j1201	2085	10	membranes	membrane	NNS
cord-022561-rv5j1201	2085	11	and	and	CC
cord-022561-rv5j1201	2085	12	enzyme	enzyme	NN
cord-022561-rv5j1201	2085	13	systems	system	NNS
cord-022561-rv5j1201	2085	14	.	.	.
cord-022561-rv5j1201	2086	1	Grossly	grossly	RB
cord-022561-rv5j1201	2086	2	,	,	,
cord-022561-rv5j1201	2086	3	the	the	DT
cord-022561-rv5j1201	2086	4	spleen	spleen	NN
cord-022561-rv5j1201	2086	5	is	be	VBZ
cord-022561-rv5j1201	2086	6	uniformly	uniformly	RB
cord-022561-rv5j1201	2086	7	enlarged	enlarged	JJ
cord-022561-rv5j1201	2086	8	and	and	CC
cord-022561-rv5j1201	2086	9	dark	dark	JJ
cord-022561-rv5j1201	2086	10	red	red	NN
cord-022561-rv5j1201	2086	11	to	to	TO
cord-022561-rv5j1201	2086	12	bluishblack	bluishblack	VB
cord-022561-rv5j1201	2086	13	and	and	CC
cord-022561-rv5j1201	2086	14	contains	contain	VBZ
cord-022561-rv5j1201	2086	15	abundant	abundant	JJ
cord-022561-rv5j1201	2086	16	unclotted	unclotte	VBN
cord-022561-rv5j1201	2086	17	blood	blood	NN
cord-022561-rv5j1201	2086	18	.	.	.
cord-022561-rv5j1201	2087	1	In	in	IN
cord-022561-rv5j1201	2087	2	peracute	peracute	NN
cord-022561-rv5j1201	2087	3	cases	case	VBZ
cord-022561-rv5j1201	2087	4	the	the	DT
cord-022561-rv5j1201	2087	5	782.e1	782.e1	CD
cord-022561-rv5j1201	2087	6	CHAPTER	chapter	NN
cord-022561-rv5j1201	2087	7	13	13	CD
cord-022561-rv5j1201	2087	8	Bone	Bone	NNP
cord-022561-rv5j1201	2087	9	Marrow	Marrow	NNP
cord-022561-rv5j1201	2087	10	,	,	,
cord-022561-rv5j1201	2087	11	Blood	blood	NN
cord-022561-rv5j1201	2087	12	Cells	cell	NNS
cord-022561-rv5j1201	2087	13	,	,	,
cord-022561-rv5j1201	2087	14	and	and	CC
cord-022561-rv5j1201	2087	15	the	the	DT
cord-022561-rv5j1201	2087	16	Lymphoid	Lymphoid	NNP
cord-022561-rv5j1201	2087	17	/	/	SYM
cord-022561-rv5j1201	2087	18	Lymphatic	Lymphatic	NNP
cord-022561-rv5j1201	2087	19	System	System	NNP
cord-022561-rv5j1201	2087	20	 	 	_SP
cord-022561-rv5j1201	2087	21	Diffuse	Diffuse	NNP
cord-022561-rv5j1201	2087	22	Granulomatous	Granulomatous	NNP
cord-022561-rv5j1201	2087	23	Disease	Disease	NNP
cord-022561-rv5j1201	2087	24	.	.	.
cord-022561-rv5j1201	2088	1	Chronic	chronic	JJ
cord-022561-rv5j1201	2088	2	infectious	infectious	JJ
cord-022561-rv5j1201	2088	3	diseases	disease	NNS
cord-022561-rv5j1201	2088	4	may	may	MD
cord-022561-rv5j1201	2088	5	cause	cause	VB
cord-022561-rv5j1201	2088	6	a	a	DT
cord-022561-rv5j1201	2088	7	uniformly	uniformly	RB
cord-022561-rv5j1201	2088	8	firm	firm	JJ
cord-022561-rv5j1201	2088	9	and	and	CC
cord-022561-rv5j1201	2088	10	enlarged	enlarged	JJ
cord-022561-rv5j1201	2088	11	spleen	spleen	NNS
cord-022561-rv5j1201	2088	12	,	,	,
cord-022561-rv5j1201	2088	13	mostly	mostly	RB
cord-022561-rv5j1201	2088	14	due	due	JJ
cord-022561-rv5j1201	2088	15	to	to	IN
cord-022561-rv5j1201	2088	16	macrophage	macrophage	NN
cord-022561-rv5j1201	2088	17	hyperplasia	hyperplasia	NN
cord-022561-rv5j1201	2088	18	and	and	CC
cord-022561-rv5j1201	2088	19	phagocytosis	phagocytosis	NN
cord-022561-rv5j1201	2088	20	,	,	,
cord-022561-rv5j1201	2088	21	diffuse	diffuse	VBP
cord-022561-rv5j1201	2088	22	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	2088	23	hyperplasia	hyperplasia	NN
cord-022561-rv5j1201	2088	24	,	,	,
cord-022561-rv5j1201	2088	25	or	or	CC
cord-022561-rv5j1201	2088	26	diffuse	diffuse	VB
cord-022561-rv5j1201	2088	27	granulomatous	granulomatous	JJ
cord-022561-rv5j1201	2088	28	disease	disease	NN
cord-022561-rv5j1201	2088	29	.	.	.
cord-022561-rv5j1201	2089	1	Diffuse	diffuse	VB
cord-022561-rv5j1201	2089	2	granulomatous	granulomatous	JJ
cord-022561-rv5j1201	2089	3	diseases	disease	NNS
cord-022561-rv5j1201	2089	4	(	(	-LRB-
cord-022561-rv5j1201	2089	5	see	see	VB
cord-022561-rv5j1201	2089	6	E-	E-	NNP
cord-022561-rv5j1201	2089	7	Table	Table	NNP
cord-022561-rv5j1201	2089	8	13	13	CD
cord-022561-rv5j1201	2089	9	-2	-2	CD
cord-022561-rv5j1201	2089	10	)	)	-RRB-
cord-022561-rv5j1201	2089	11	occur	occur	VBP
cord-022561-rv5j1201	2089	12	in	in	IN
cord-022561-rv5j1201	2089	13	(	(	-LRB-
cord-022561-rv5j1201	2089	14	1	1	CD
cord-022561-rv5j1201	2089	15	)	)	-RRB-
cord-022561-rv5j1201	2089	16	intracellular	intracellular	JJ
cord-022561-rv5j1201	2089	17	facultative	facultative	JJ
cord-022561-rv5j1201	2089	18	bacteria	bacteria	NNS
cord-022561-rv5j1201	2089	19	that	that	WDT
cord-022561-rv5j1201	2089	20	infect	infect	VBP
cord-022561-rv5j1201	2089	21	macrophages	macrophage	NNS
cord-022561-rv5j1201	2089	22	(	(	-LRB-
cord-022561-rv5j1201	2089	23	e.g.	e.g.	RB
cord-022561-rv5j1201	2089	24	,	,	,
cord-022561-rv5j1201	2089	25	Mycobacterium	Mycobacterium	NNP
cord-022561-rv5j1201	2089	26	spp	spp	NNS
cord-022561-rv5j1201	2089	27	.	.	.
cord-022561-rv5j1201	2090	1	,	,	,
cord-022561-rv5j1201	2090	2	Brucella	Brucella	NNP
cord-022561-rv5j1201	2090	3	spp	spp	NNS
cord-022561-rv5j1201	2090	4	.	.	.
cord-022561-rv5j1201	2091	1	,	,	,
cord-022561-rv5j1201	2091	2	and	and	CC
cord-022561-rv5j1201	2091	3	Francisella	Francisella	NNP
cord-022561-rv5j1201	2091	4	tularensis	tularensis	NNP
cord-022561-rv5j1201	2091	5	)	)	-RRB-
cord-022561-rv5j1201	2091	6	;	;	:
cord-022561-rv5j1201	2091	7	(	(	-LRB-
cord-022561-rv5j1201	2091	8	2	2	LS
cord-022561-rv5j1201	2091	9	)	)	-RRB-
cord-022561-rv5j1201	2091	10	systemic	systemic	JJ
cord-022561-rv5j1201	2091	11	mycoses	mycose	NNS
cord-022561-rv5j1201	2091	12	(	(	-LRB-
cord-022561-rv5j1201	2091	13	e.g.	e.g.	RB
cord-022561-rv5j1201	2091	14	,	,	,
cord-022561-rv5j1201	2091	15	Blastomyces	Blastomyces	NNP
cord-022561-rv5j1201	2091	16	dermatitidis	dermatitidis	NN
cord-022561-rv5j1201	2091	17	,	,	,
cord-022561-rv5j1201	2091	18	Histoplasma	Histoplasma	NNP
cord-022561-rv5j1201	2091	19	capsulatum	capsulatum	NN
cord-022561-rv5j1201	2091	20	)	)	-RRB-
cord-022561-rv5j1201	2092	1	(	(	-LRB-
cord-022561-rv5j1201	2092	2	see	see	VB
cord-022561-rv5j1201	2092	3	Lymphoid	Lymphoid	NNP
cord-022561-rv5j1201	2092	4	/	/	SYM
cord-022561-rv5j1201	2092	5	Lymphatic	Lymphatic	NNP
cord-022561-rv5j1201	2092	6	System	System	NNP
cord-022561-rv5j1201	2092	7	,	,	,
cord-022561-rv5j1201	2092	8	Disorders	disorder	NNS
cord-022561-rv5j1201	2092	9	of	of	IN
cord-022561-rv5j1201	2092	10	Domestic	domestic	JJ
cord-022561-rv5j1201	2092	11	Animals	animal	NNS
cord-022561-rv5j1201	2092	12	:	:	:
cord-022561-rv5j1201	2092	13	Lymph	lymph	NN
cord-022561-rv5j1201	2092	14	Nodes	node	NNS
cord-022561-rv5j1201	2092	15	,	,	,
cord-022561-rv5j1201	2092	16	Enlarged	enlarged	JJ
cord-022561-rv5j1201	2092	17	Lymph	lymph	NN
cord-022561-rv5j1201	2092	18	Nodes	node	NNS
cord-022561-rv5j1201	2092	19	[	[	-LRB-
cord-022561-rv5j1201	2092	20	Lymphadenomegaly	Lymphadenomegaly	NNP
cord-022561-rv5j1201	2092	21	]	]	-RRB-
cord-022561-rv5j1201	2092	22	)	)	-RRB-
cord-022561-rv5j1201	2093	1	(	(	-LRB-
cord-022561-rv5j1201	2093	2	Fig	Fig	NNP
cord-022561-rv5j1201	2093	3	.	.	.
cord-022561-rv5j1201	2093	4	13	13	CD
cord-022561-rv5j1201	2093	5	-	-	SYM
cord-022561-rv5j1201	2093	6	59	59	CD
cord-022561-rv5j1201	2093	7	,	,	,
cord-022561-rv5j1201	2093	8	A	a	NN
cord-022561-rv5j1201	2093	9	and	and	CC
cord-022561-rv5j1201	2093	10	B	B	NNP
cord-022561-rv5j1201	2093	11	)	)	-RRB-
cord-022561-rv5j1201	2093	12	,	,	,
cord-022561-rv5j1201	2093	13	and	and	CC
cord-022561-rv5j1201	2093	14	(	(	-LRB-
cord-022561-rv5j1201	2093	15	3	3	LS
cord-022561-rv5j1201	2093	16	)	)	-RRB-
cord-022561-rv5j1201	2093	17	protozoal	protozoal	JJ
cord-022561-rv5j1201	2093	18	infections	infection	NNS
cord-022561-rv5j1201	2093	19	that	that	WDT
cord-022561-rv5j1201	2093	20	infect	infect	VBP
cord-022561-rv5j1201	2093	21	macrophages	macrophage	NNS
cord-022561-rv5j1201	2093	22	(	(	-LRB-
cord-022561-rv5j1201	2093	23	e.g.	e.g.	RB
cord-022561-rv5j1201	2093	24	,	,	,
cord-022561-rv5j1201	2093	25	Leishmania	Leishmania	NNP
cord-022561-rv5j1201	2093	26	spp	spp	NNP
cord-022561-rv5j1201	2093	27	.	.	.
cord-022561-rv5j1201	2093	28	)	)	-RRB-
cord-022561-rv5j1201	2093	29	.	.	.
cord-022561-rv5j1201	2094	1	Some	some	DT
cord-022561-rv5j1201	2094	2	of	of	IN
cord-022561-rv5j1201	2094	3	these	these	DT
cord-022561-rv5j1201	2094	4	organisms	organism	NNS
cord-022561-rv5j1201	2094	5	may	may	MD
cord-022561-rv5j1201	2094	6	also	also	RB
cord-022561-rv5j1201	2094	7	produce	produce	VB
cord-022561-rv5j1201	2094	8	nodular	nodular	JJ
cord-022561-rv5j1201	2094	9	spleens	spleen	NNS
cord-022561-rv5j1201	2094	10	with	with	IN
cord-022561-rv5j1201	2094	11	the	the	DT
cord-022561-rv5j1201	2094	12	formation	formation	NN
cord-022561-rv5j1201	2094	13	of	of	IN
cord-022561-rv5j1201	2094	14	discrete	discrete	JJ
cord-022561-rv5j1201	2094	15	to	to	IN
cord-022561-rv5j1201	2094	16	coalescing	coalesce	VBG
cord-022561-rv5j1201	2094	17	granulomas	granuloma	NNS
cord-022561-rv5j1201	2094	18	(	(	-LRB-
cord-022561-rv5j1201	2094	19	e.g.	e.g.	RB
cord-022561-rv5j1201	2094	20	,	,	,
cord-022561-rv5j1201	2094	21	M.	M.	NNP
cord-022561-rv5j1201	2094	22	bovis	bovis	NNP
cord-022561-rv5j1201	2094	23	)	)	-RRB-
cord-022561-rv5j1201	2094	24	(	(	-LRB-
cord-022561-rv5j1201	2094	25	see	see	VB
cord-022561-rv5j1201	2094	26	Splenic	Splenic	NNP
cord-022561-rv5j1201	2094	27	Nodules	Nodules	NNPS
cord-022561-rv5j1201	2094	28	with	with	IN
cord-022561-rv5j1201	2094	29	a	a	DT
cord-022561-rv5j1201	2094	30	Firm	Firm	NNP
cord-022561-rv5j1201	2094	31	Consistency	Consistency	NNP
cord-022561-rv5j1201	2094	32	)	)	-RRB-
cord-022561-rv5j1201	2094	33	.	.	.
cord-022561-rv5j1201	2095	1	follicles	follicle	NNS
cord-022561-rv5j1201	2095	2	throughout	throughout	IN
cord-022561-rv5j1201	2095	3	the	the	DT
cord-022561-rv5j1201	2095	4	splenic	splenic	JJ
cord-022561-rv5j1201	2095	5	parenchyma	parenchyma	NNS
cord-022561-rv5j1201	2095	6	can	can	MD
cord-022561-rv5j1201	2095	7	become	become	VB
cord-022561-rv5j1201	2095	8	enlarged	enlarged	JJ
cord-022561-rv5j1201	2095	9	and	and	CC
cord-022561-rv5j1201	2095	10	visible	visible	JJ
cord-022561-rv5j1201	2095	11	on	on	IN
cord-022561-rv5j1201	2095	12	gross	gross	JJ
cord-022561-rv5j1201	2095	13	examination	examination	NN
cord-022561-rv5j1201	2096	1	(	(	-LRB-
cord-022561-rv5j1201	2096	2	Fig	Fig	NNP
cord-022561-rv5j1201	2096	3	.	.	.
cord-022561-rv5j1201	2096	4	13	13	CD
cord-022561-rv5j1201	2096	5	-	-	SYM
cord-022561-rv5j1201	2096	6	58	58	CD
cord-022561-rv5j1201	2096	7	)	)	-RRB-
cord-022561-rv5j1201	2096	8	,	,	,
cord-022561-rv5j1201	2096	9	leading	lead	VBG
cord-022561-rv5j1201	2096	10	to	to	IN
cord-022561-rv5j1201	2096	11	diffuse	diffuse	VB
cord-022561-rv5j1201	2096	12	splenomegaly	splenomegaly	NN
cord-022561-rv5j1201	2096	13	.	.	.
cord-022561-rv5j1201	2097	1	In	in	IN
cord-022561-rv5j1201	2097	2	contrast	contrast	NN
cord-022561-rv5j1201	2097	3	to	to	IN
cord-022561-rv5j1201	2097	4	B	b	NN
cord-022561-rv5j1201	2097	5	lymphocyte	lymphocyte	NN
cord-022561-rv5j1201	2097	6	hyperplasia	hyperplasia	NN
cord-022561-rv5j1201	2097	7	of	of	IN
cord-022561-rv5j1201	2097	8	the	the	DT
cord-022561-rv5j1201	2097	9	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	2097	10	follicles	follicle	NNS
cord-022561-rv5j1201	2097	11	,	,	,
cord-022561-rv5j1201	2097	12	certain	certain	JJ
cord-022561-rv5j1201	2097	13	diseases	disease	NNS
cord-022561-rv5j1201	2097	14	(	(	-LRB-
cord-022561-rv5j1201	2097	15	e.g.	e.g.	RB
cord-022561-rv5j1201	2097	16	,	,	,
cord-022561-rv5j1201	2097	17	malignant	malignant	JJ
cord-022561-rv5j1201	2097	18	catarrhal	catarrhal	NN
cord-022561-rv5j1201	2097	19	fever	fever	NN
cord-022561-rv5j1201	2097	20	in	in	IN
cord-022561-rv5j1201	2097	21	cattle	cattle	NNS
cord-022561-rv5j1201	2097	22	)	)	-RRB-
cord-022561-rv5j1201	2097	23	may	may	MD
cord-022561-rv5j1201	2097	24	lead	lead	VB
cord-022561-rv5j1201	2097	25	to	to	IN
cord-022561-rv5j1201	2097	26	T	t	NN
cord-022561-rv5j1201	2097	27	lymphocyte	lymphocyte	NN
cord-022561-rv5j1201	2097	28	hyperplasia	hyperplasia	NN
cord-022561-rv5j1201	2097	29	of	of	IN
cord-022561-rv5j1201	2097	30	the	the	DT
cord-022561-rv5j1201	2097	31	PALS	pals	NN
cord-022561-rv5j1201	2097	32	.	.	.
cord-022561-rv5j1201	2098	1	Diffuse	diffuse	JJ
cord-022561-rv5j1201	2098	2	Histiocytic	Histiocytic	NNP
cord-022561-rv5j1201	2098	3	Hyperplasia	Hyperplasia	NNP
cord-022561-rv5j1201	2098	4	and	and	CC
cord-022561-rv5j1201	2098	5	Phagocytosis	Phagocytosis	NNP
cord-022561-rv5j1201	2098	6	.	.	.
cord-022561-rv5j1201	2099	1	Splenomegaly	Splenomegaly	NNP
cord-022561-rv5j1201	2099	2	from	from	IN
cord-022561-rv5j1201	2099	3	hyperplasia	hyperplasia	NN
cord-022561-rv5j1201	2099	4	and	and	CC
cord-022561-rv5j1201	2099	5	increased	increase	VBN
cord-022561-rv5j1201	2099	6	phagocytosis	phagocytosis	NN
cord-022561-rv5j1201	2099	7	of	of	IN
cord-022561-rv5j1201	2099	8	splenic	splenic	JJ
cord-022561-rv5j1201	2099	9	macrophages	macrophage	NNS
cord-022561-rv5j1201	2099	10	is	be	VBZ
cord-022561-rv5j1201	2099	11	a	a	DT
cord-022561-rv5j1201	2099	12	response	response	NN
cord-022561-rv5j1201	2099	13	to	to	IN
cord-022561-rv5j1201	2099	14	the	the	DT
cord-022561-rv5j1201	2099	15	need	need	NN
cord-022561-rv5j1201	2099	16	to	to	TO
cord-022561-rv5j1201	2099	17	engulf	engulf	VB
cord-022561-rv5j1201	2099	18	organisms	organism	NNS
cord-022561-rv5j1201	2099	19	in	in	IN
cord-022561-rv5j1201	2099	20	prolonged	prolonged	JJ
cord-022561-rv5j1201	2099	21	bacteremia	bacteremia	NN
cord-022561-rv5j1201	2099	22	or	or	CC
cord-022561-rv5j1201	2099	23	parasitemia	parasitemia	NN
cord-022561-rv5j1201	2099	24	from	from	IN
cord-022561-rv5j1201	2099	25	hemotropic	hemotropic	NNP
cord-022561-rv5j1201	2099	26	organisms	organism	NNS
cord-022561-rv5j1201	2099	27	.	.	.
cord-022561-rv5j1201	2100	1	Whereas	whereas	IN
cord-022561-rv5j1201	2100	2	acute	acute	JJ
cord-022561-rv5j1201	2100	3	hemolytic	hemolytic	JJ
cord-022561-rv5j1201	2100	4	anemias	anemia	NNS
cord-022561-rv5j1201	2100	5	cause	cause	VBP
cord-022561-rv5j1201	2100	6	splenomegaly	splenomegaly	NN
cord-022561-rv5j1201	2100	7	with	with	IN
cord-022561-rv5j1201	2100	8	congestion	congestion	NN
cord-022561-rv5j1201	2100	9	(	(	-LRB-
cord-022561-rv5j1201	2100	10	bloody	bloody	JJ
cord-022561-rv5j1201	2100	11	spleen	spleen	NNS
cord-022561-rv5j1201	2100	12	)	)	-RRB-
cord-022561-rv5j1201	2100	13	,	,	,
cord-022561-rv5j1201	2100	14	with	with	IN
cord-022561-rv5j1201	2100	15	chronicity	chronicity	NN
cord-022561-rv5j1201	2100	16	there	there	EX
cord-022561-rv5j1201	2100	17	is	be	VBZ
cord-022561-rv5j1201	2100	18	decreased	decrease	VBN
cord-022561-rv5j1201	2100	19	sequestration	sequestration	NN
cord-022561-rv5j1201	2100	20	of	of	IN
cord-022561-rv5j1201	2100	21	diseased	diseased	JJ
cord-022561-rv5j1201	2100	22	erythrocytes	erythrocyte	NNS
cord-022561-rv5j1201	2100	23	and	and	CC
cord-022561-rv5j1201	2100	24	hence	hence	RB
cord-022561-rv5j1201	2100	25	less	less	JJR
cord-022561-rv5j1201	2100	26	congestion	congestion	NN
cord-022561-rv5j1201	2100	27	.	.	.
cord-022561-rv5j1201	2101	1	Therefore	therefore	RB
cord-022561-rv5j1201	2101	2	in	in	IN
cord-022561-rv5j1201	2101	3	cases	case	NNS
cord-022561-rv5j1201	2101	4	of	of	IN
cord-022561-rv5j1201	2101	5	chronic	chronic	JJ
cord-022561-rv5j1201	2101	6	hemolytic	hemolytic	JJ
cord-022561-rv5j1201	2101	7	disease	disease	NN
cord-022561-rv5j1201	2101	8	,	,	,
cord-022561-rv5j1201	2101	9	splenomegaly	splenomegaly	NN
cord-022561-rv5j1201	2101	10	is	be	VBZ
cord-022561-rv5j1201	2101	11	attributed	attribute	VBN
cord-022561-rv5j1201	2101	12	to	to	TO
cord-022561-rv5j1201	2101	13	diffuse	diffuse	VB
cord-022561-rv5j1201	2101	14	proliferation	proliferation	NN
cord-022561-rv5j1201	2101	15	of	of	IN
cord-022561-rv5j1201	2101	16	macrophages	macrophage	NNS
cord-022561-rv5j1201	2101	17	,	,	,
cord-022561-rv5j1201	2101	18	phagocytosis	phagocytosis	NN
cord-022561-rv5j1201	2101	19	,	,	,
cord-022561-rv5j1201	2101	20	and	and	CC
cord-022561-rv5j1201	2101	21	concurrent	concurrent	JJ
cord-022561-rv5j1201	2101	22	hyperplasia	hyperplasia	NN
cord-022561-rv5j1201	2101	23	of	of	IN
cord-022561-rv5j1201	2101	24	the	the	DT
cord-022561-rv5j1201	2101	25	white	white	JJ
cord-022561-rv5j1201	2101	26	pulp	pulp	NN
cord-022561-rv5j1201	2101	27	due	due	IN
cord-022561-rv5j1201	2101	28	to	to	IN
cord-022561-rv5j1201	2101	29	ongoing	ongoing	JJ
cord-022561-rv5j1201	2101	30	antigenic	antigenic	JJ
cord-022561-rv5j1201	2101	31	stimulation	stimulation	NN
cord-022561-rv5j1201	2101	32	.	.	.
cord-022561-rv5j1201	2102	1	For	for	IN
cord-022561-rv5j1201	2102	2	example	example	NN
cord-022561-rv5j1201	2102	3	,	,	,
cord-022561-rv5j1201	2102	4	equine	equine	JJ
cord-022561-rv5j1201	2102	5	infectious	infectious	JJ
cord-022561-rv5j1201	2102	6	anemia	anemia	NN
cord-022561-rv5j1201	2102	7	has	have	VBZ
cord-022561-rv5j1201	2102	8	cyclical	cyclical	JJ
cord-022561-rv5j1201	2102	9	periods	period	NNS
cord-022561-rv5j1201	2102	10	of	of	IN
cord-022561-rv5j1201	2102	11	viremia	viremia	NN
cord-022561-rv5j1201	2102	12	,	,	,
cord-022561-rv5j1201	2102	13	with	with	IN
cord-022561-rv5j1201	2102	14	immune	immune	NN
cord-022561-rv5j1201	2102	15	-	-	HYPH
cord-022561-rv5j1201	2102	16	mediated	mediate	VBN
cord-022561-rv5j1201	2102	17	damage	damage	NN
cord-022561-rv5j1201	2102	18	to	to	IN
cord-022561-rv5j1201	2102	19	erythrocytes	erythrocyte	NNS
cord-022561-rv5j1201	2102	20	and	and	CC
cord-022561-rv5j1201	2102	21	platelets	platelet	NNS
cord-022561-rv5j1201	2102	22	,	,	,
cord-022561-rv5j1201	2102	23	and	and	CC
cord-022561-rv5j1201	2102	24	phagocytosis	phagocytosis	NN
cord-022561-rv5j1201	2102	25	to	to	TO
cord-022561-rv5j1201	2102	26	remove	remove	VB
cord-022561-rv5j1201	2102	27	altered	altered	JJ
cord-022561-rv5j1201	2102	28	erythrocytes	erythrocyte	NNS
cord-022561-rv5j1201	2102	29	and	and	CC
cord-022561-rv5j1201	2102	30	platelets	platelet	NNS
cord-022561-rv5j1201	2102	31	.	.	.
cord-022561-rv5j1201	2103	1	These	these	DT
cord-022561-rv5j1201	2103	2	cycles	cycle	NNS
cord-022561-rv5j1201	2103	3	result	result	VBP
cord-022561-rv5j1201	2103	4	in	in	IN
cord-022561-rv5j1201	2103	5	proliferation	proliferation	NN
cord-022561-rv5j1201	2103	6	of	of	IN
cord-022561-rv5j1201	2103	7	red	red	JJ
cord-022561-rv5j1201	2103	8	pulp	pulp	NN
cord-022561-rv5j1201	2103	9	macrophages	macrophage	NNS
cord-022561-rv5j1201	2103	10	,	,	,
cord-022561-rv5j1201	2103	11	hyperplasia	hyperplasia	NN
cord-022561-rv5j1201	2103	12	of	of	IN
cord-022561-rv5j1201	2103	13	hematopoietic	hematopoietic	JJ
cord-022561-rv5j1201	2103	14	cells	cell	NNS
cord-022561-rv5j1201	2103	15	(	(	-LRB-
cord-022561-rv5j1201	2103	16	EMH	EMH	NNP
cord-022561-rv5j1201	2103	17	)	)	-RRB-
cord-022561-rv5j1201	2103	18	to	to	TO
cord-022561-rv5j1201	2103	19	replace	replace	VB
cord-022561-rv5j1201	2103	20	those	those	DT
cord-022561-rv5j1201	2103	21	lost	lose	VBN
cord-022561-rv5j1201	2103	22	,	,	,
cord-022561-rv5j1201	2103	23	and	and	CC
cord-022561-rv5j1201	2103	24	hyperplasia	hyperplasia	NN
cord-022561-rv5j1201	2103	25	of	of	IN
cord-022561-rv5j1201	2103	26	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	2103	27	in	in	IN
cord-022561-rv5j1201	2103	28	the	the	DT
cord-022561-rv5j1201	2103	29	white	white	JJ
cord-022561-rv5j1201	2103	30	pulp	pulp	NN
cord-022561-rv5j1201	2103	31	.	.	.
cord-022561-rv5j1201	2103	32	 	 	_SP
cord-022561-rv5j1201	2104	1	in	in	IN
cord-022561-rv5j1201	2104	2	animals	animal	NNS
cord-022561-rv5j1201	2104	3	less	less	JJR
cord-022561-rv5j1201	2104	4	than	than	IN
cord-022561-rv5j1201	2104	5	1	1	CD
cord-022561-rv5j1201	2104	6	year	year	NN
cord-022561-rv5j1201	2104	7	of	of	IN
cord-022561-rv5j1201	2104	8	age	age	NN
cord-022561-rv5j1201	2104	9	.	.	.
cord-022561-rv5j1201	2105	1	In	in	IN
cord-022561-rv5j1201	2105	2	general	general	JJ
cord-022561-rv5j1201	2105	3	,	,	,
cord-022561-rv5j1201	2105	4	these	these	DT
cord-022561-rv5j1201	2105	5	substrates	substrate	NNS
cord-022561-rv5j1201	2105	6	are	be	VBP
cord-022561-rv5j1201	2105	7	lipids	lipid	NNS
cord-022561-rv5j1201	2105	8	and/or	and/or	CC
cord-022561-rv5j1201	2105	9	carbohydrates	carbohydrate	NNS
cord-022561-rv5j1201	2105	10	that	that	WDT
cord-022561-rv5j1201	2105	11	accumulate	accumulate	VBP
cord-022561-rv5j1201	2105	12	in	in	IN
cord-022561-rv5j1201	2105	13	the	the	DT
cord-022561-rv5j1201	2105	14	cells	cell	NNS
cord-022561-rv5j1201	2105	15	,	,	,
cord-022561-rv5j1201	2105	16	the	the	DT
cord-022561-rv5j1201	2105	17	result	result	NN
cord-022561-rv5j1201	2105	18	of	of	IN
cord-022561-rv5j1201	2105	19	the	the	DT
cord-022561-rv5j1201	2105	20	lack	lack	NN
cord-022561-rv5j1201	2105	21	of	of	IN
cord-022561-rv5j1201	2105	22	normal	normal	JJ
cord-022561-rv5j1201	2105	23	processing	processing	NN
cord-022561-rv5j1201	2105	24	within	within	IN
cord-022561-rv5j1201	2105	25	lysosomes	lysosome	NNS
cord-022561-rv5j1201	2105	26	.	.	.
cord-022561-rv5j1201	2106	1	Major	major	JJ
cord-022561-rv5j1201	2106	2	categories	category	NNS
cord-022561-rv5j1201	2106	3	of	of	IN
cord-022561-rv5j1201	2106	4	stored	store	VBN
cord-022561-rv5j1201	2106	5	materials	material	NNS
cord-022561-rv5j1201	2106	6	include	include	VBP
cord-022561-rv5j1201	2106	7	mucopolysaccharides	mucopolysaccharide	NNS
cord-022561-rv5j1201	2106	8	,	,	,
cord-022561-rv5j1201	2106	9	sphingolipids	sphingolipid	NNS
cord-022561-rv5j1201	2106	10	,	,	,
cord-022561-rv5j1201	2106	11	glycolipids	glycolipid	NNS
cord-022561-rv5j1201	2106	12	,	,	,
cord-022561-rv5j1201	2106	13	glycoproteins	glycoprotein	NNS
cord-022561-rv5j1201	2106	14	,	,	,
cord-022561-rv5j1201	2106	15	glycogen	glycogen	NN
cord-022561-rv5j1201	2106	16	,	,	,
cord-022561-rv5j1201	2106	17	and	and	CC
cord-022561-rv5j1201	2106	18	oligosaccharides	oligosaccharide	NNS
cord-022561-rv5j1201	2106	19	.	.	.
cord-022561-rv5j1201	2107	1	Macrophages	macrophage	NNS
cord-022561-rv5j1201	2107	2	are	be	VBP
cord-022561-rv5j1201	2107	3	commonly	commonly	RB
cord-022561-rv5j1201	2107	4	affected	affect	VBN
cord-022561-rv5j1201	2107	5	by	by	IN
cord-022561-rv5j1201	2107	6	storage	storage	NN
cord-022561-rv5j1201	2107	7	diseases	disease	NNS
cord-022561-rv5j1201	2107	8	,	,	,
cord-022561-rv5j1201	2107	9	and	and	CC
cord-022561-rv5j1201	2107	10	thus	thus	RB
cord-022561-rv5j1201	2107	11	Extramedullary	Extramedullary	NNP
cord-022561-rv5j1201	2107	12	Hematopoiesis	Hematopoiesis	NNP
cord-022561-rv5j1201	2107	13	.	.	.
cord-022561-rv5j1201	2108	1	EMH	EMH	NNP
cord-022561-rv5j1201	2108	2	is	be	VBZ
cord-022561-rv5j1201	2108	3	the	the	DT
cord-022561-rv5j1201	2108	4	development	development	NN
cord-022561-rv5j1201	2108	5	of	of	IN
cord-022561-rv5j1201	2108	6	blood	blood	NN
cord-022561-rv5j1201	2108	7	cells	cell	NNS
cord-022561-rv5j1201	2108	8	in	in	IN
cord-022561-rv5j1201	2108	9	tissues	tissue	NNS
cord-022561-rv5j1201	2108	10	outside	outside	IN
cord-022561-rv5j1201	2108	11	the	the	DT
cord-022561-rv5j1201	2108	12	medullary	medullary	JJ
cord-022561-rv5j1201	2108	13	cavity	cavity	NN
cord-022561-rv5j1201	2108	14	of	of	IN
cord-022561-rv5j1201	2108	15	the	the	DT
cord-022561-rv5j1201	2108	16	bone	bone	NN
cord-022561-rv5j1201	2109	1	(	(	-LRB-
cord-022561-rv5j1201	2109	2	E-	E-	NNP
cord-022561-rv5j1201	2109	3	Fig	Fig	NNP
cord-022561-rv5j1201	2109	4	.	.	.
cord-022561-rv5j1201	2109	5	 	 	_SP
cord-022561-rv5j1201	2110	1	13	13	CD
cord-022561-rv5j1201	2110	2	-	-	SYM
cord-022561-rv5j1201	2110	3	9	9	CD
cord-022561-rv5j1201	2110	4	)	)	-RRB-
cord-022561-rv5j1201	2110	5	.	.	.
cord-022561-rv5j1201	2111	1	The	the	DT
cord-022561-rv5j1201	2111	2	formation	formation	NN
cord-022561-rv5j1201	2111	3	of	of	IN
cord-022561-rv5j1201	2111	4	single	single	JJ
cord-022561-rv5j1201	2111	5	or	or	CC
cord-022561-rv5j1201	2111	6	multiple	multiple	JJ
cord-022561-rv5j1201	2111	7	lineages	lineage	NNS
cord-022561-rv5j1201	2111	8	of	of	IN
cord-022561-rv5j1201	2111	9	hematopoietic	hematopoietic	JJ
cord-022561-rv5j1201	2111	10	cells	cell	NNS
cord-022561-rv5j1201	2111	11	is	be	VBZ
cord-022561-rv5j1201	2111	12	often	often	RB
cord-022561-rv5j1201	2111	13	observed	observe	VBN
cord-022561-rv5j1201	2111	14	in	in	IN
cord-022561-rv5j1201	2111	15	many	many	JJ
cord-022561-rv5j1201	2111	16	tissues	tissue	NNS
cord-022561-rv5j1201	2111	17	and	and	CC
cord-022561-rv5j1201	2111	18	commonly	commonly	RB
cord-022561-rv5j1201	2111	19	in	in	IN
cord-022561-rv5j1201	2111	20	the	the	DT
cord-022561-rv5j1201	2111	21	spleen	spleen	NN
cord-022561-rv5j1201	2111	22	.	.	.
cord-022561-rv5j1201	2112	1	The	the	DT
cord-022561-rv5j1201	2112	2	ability	ability	NN
cord-022561-rv5j1201	2112	3	of	of	IN
cord-022561-rv5j1201	2112	4	blood	blood	NN
cord-022561-rv5j1201	2112	5	cell	cell	NN
cord-022561-rv5j1201	2112	6	precursors	precursor	NNS
cord-022561-rv5j1201	2112	7	to	to	IN
cord-022561-rv5j1201	2112	8	home	home	NN
cord-022561-rv5j1201	2112	9	,	,	,
cord-022561-rv5j1201	2112	10	proliferate	proliferate	VB
cord-022561-rv5j1201	2112	11	,	,	,
cord-022561-rv5j1201	2112	12	and	and	CC
cord-022561-rv5j1201	2112	13	mature	mature	VB
cord-022561-rv5j1201	2112	14	in	in	IN
cord-022561-rv5j1201	2112	15	extramedullary	extramedullary	JJ
cord-022561-rv5j1201	2112	16	sites	site	NNS
cord-022561-rv5j1201	2112	17	relies	rely	VBZ
cord-022561-rv5j1201	2112	18	on	on	IN
cord-022561-rv5j1201	2112	19	the	the	DT
cord-022561-rv5j1201	2112	20	presence	presence	NN
cord-022561-rv5j1201	2112	21	of	of	IN
cord-022561-rv5j1201	2112	22	HSCs	hscs	NN
cord-022561-rv5j1201	2112	23	and	and	CC
cord-022561-rv5j1201	2112	24	pathophysiologic	pathophysiologic	NN
cord-022561-rv5j1201	2112	25	changes	change	NNS
cord-022561-rv5j1201	2112	26	in	in	IN
cord-022561-rv5j1201	2112	27	the	the	DT
cord-022561-rv5j1201	2112	28	microenvironment	microenvironment	NN
cord-022561-rv5j1201	2112	29	(	(	-LRB-
cord-022561-rv5j1201	2112	30	i.e.	i.e.	FW
cord-022561-rv5j1201	2112	31	,	,	,
cord-022561-rv5j1201	2112	32	extracellular	extracellular	JJ
cord-022561-rv5j1201	2112	33	matrix	matrix	NN
cord-022561-rv5j1201	2112	34	,	,	,
cord-022561-rv5j1201	2112	35	stroma	stroma	NN
cord-022561-rv5j1201	2112	36	,	,	,
cord-022561-rv5j1201	2112	37	and	and	CC
cord-022561-rv5j1201	2112	38	chemokines	chemokine	NNS
cord-022561-rv5j1201	2112	39	)	)	-RRB-
cord-022561-rv5j1201	2112	40	.	.	.
cord-022561-rv5j1201	2113	1	In	in	IN
cord-022561-rv5j1201	2113	2	the	the	DT
cord-022561-rv5j1201	2113	3	spleen	spleen	NN
cord-022561-rv5j1201	2113	4	,	,	,
cord-022561-rv5j1201	2113	5	HSCs	hscs	NN
cord-022561-rv5j1201	2113	6	have	have	VBP
cord-022561-rv5j1201	2113	7	been	be	VBN
cord-022561-rv5j1201	2113	8	found	find	VBN
cord-022561-rv5j1201	2113	9	within	within	IN
cord-022561-rv5j1201	2113	10	vessels	vessel	NNS
cord-022561-rv5j1201	2113	11	and	and	CC
cord-022561-rv5j1201	2113	12	adjacent	adjacent	JJ
cord-022561-rv5j1201	2113	13	to	to	IN
cord-022561-rv5j1201	2113	14	endothelial	endothelial	JJ
cord-022561-rv5j1201	2113	15	cells	cell	NNS
cord-022561-rv5j1201	2113	16	to	to	TO
cord-022561-rv5j1201	2113	17	form	form	VB
cord-022561-rv5j1201	2113	18	a	a	DT
cord-022561-rv5j1201	2113	19	vascular	vascular	JJ
cord-022561-rv5j1201	2113	20	niche	niche	NN
cord-022561-rv5j1201	2113	21	;	;	:
cord-022561-rv5j1201	2113	22	thus	thus	RB
cord-022561-rv5j1201	2113	23	splenic	splenic	JJ
cord-022561-rv5j1201	2113	24	EMH	EMH	NNP
cord-022561-rv5j1201	2113	25	occurs	occur	VBZ
cord-022561-rv5j1201	2113	26	in	in	IN
cord-022561-rv5j1201	2113	27	the	the	DT
cord-022561-rv5j1201	2113	28	red	red	JJ
cord-022561-rv5j1201	2113	29	pulp	pulp	NN
cord-022561-rv5j1201	2113	30	,	,	,
cord-022561-rv5j1201	2113	31	both	both	DT
cord-022561-rv5j1201	2113	32	within	within	IN
cord-022561-rv5j1201	2113	33	the	the	DT
cord-022561-rv5j1201	2113	34	red	red	JJ
cord-022561-rv5j1201	2113	35	pulp	pulp	NN
cord-022561-rv5j1201	2113	36	vascular	vascular	JJ
cord-022561-rv5j1201	2113	37	spaces	space	NNS
cord-022561-rv5j1201	2113	38	and	and	CC
cord-022561-rv5j1201	2113	39	sinusoids	sinusoid	NNS
cord-022561-rv5j1201	2113	40	(	(	-LRB-
cord-022561-rv5j1201	2113	41	of	of	IN
cord-022561-rv5j1201	2113	42	the	the	DT
cord-022561-rv5j1201	2113	43	dog	dog	NN
cord-022561-rv5j1201	2113	44	)	)	-RRB-
cord-022561-rv5j1201	2113	45	.	.	.
cord-022561-rv5j1201	2114	1	The	the	DT
cord-022561-rv5j1201	2114	2	predilection	predilection	NN
cord-022561-rv5j1201	2114	3	for	for	IN
cord-022561-rv5j1201	2114	4	EMH	EMH	NNP
cord-022561-rv5j1201	2114	5	to	to	TO
cord-022561-rv5j1201	2114	6	occur	occur	VB
cord-022561-rv5j1201	2114	7	varies	vary	VBZ
cord-022561-rv5j1201	2114	8	among	among	IN
cord-022561-rv5j1201	2114	9	species	specie	NNS
cord-022561-rv5j1201	2114	10	(	(	-LRB-
cord-022561-rv5j1201	2114	11	for	for	IN
cord-022561-rv5j1201	2114	12	instance	instance	NN
cord-022561-rv5j1201	2114	13	,	,	,
cord-022561-rv5j1201	2114	14	splenic	splenic	JJ
cord-022561-rv5j1201	2114	15	EMH	EMH	NNP
cord-022561-rv5j1201	2114	16	persists	persist	VBZ
cord-022561-rv5j1201	2114	17	throughout	throughout	IN
cord-022561-rv5j1201	2114	18	adulthood	adulthood	NN
cord-022561-rv5j1201	2114	19	in	in	IN
cord-022561-rv5j1201	2114	20	mice	mouse	NNS
cord-022561-rv5j1201	2114	21	)	)	-RRB-
cord-022561-rv5j1201	2114	22	,	,	,
cord-022561-rv5j1201	2114	23	and	and	CC
cord-022561-rv5j1201	2114	24	the	the	DT
cord-022561-rv5j1201	2114	25	underlying	underlie	VBG
cord-022561-rv5j1201	2114	26	mechanisms	mechanism	NNS
cord-022561-rv5j1201	2114	27	are	be	VBP
cord-022561-rv5j1201	2114	28	not	not	RB
cord-022561-rv5j1201	2114	29	completely	completely	RB
cord-022561-rv5j1201	2114	30	understood	understand	VBN
cord-022561-rv5j1201	2114	31	,	,	,
cord-022561-rv5j1201	2114	32	but	but	CC
cord-022561-rv5j1201	2114	33	four	four	CD
cord-022561-rv5j1201	2114	34	major	major	JJ
cord-022561-rv5j1201	2114	35	theories	theory	NNS
cord-022561-rv5j1201	2114	36	to	to	TO
cord-022561-rv5j1201	2114	37	explain	explain	VB
cord-022561-rv5j1201	2114	38	the	the	DT
cord-022561-rv5j1201	2114	39	causes	cause	NNS
cord-022561-rv5j1201	2114	40	of	of	IN
cord-022561-rv5j1201	2114	41	EMH	EMH	NNP
cord-022561-rv5j1201	2114	42	are	be	VBP
cord-022561-rv5j1201	2114	43	(	(	-LRB-
cord-022561-rv5j1201	2114	44	1	1	CD
cord-022561-rv5j1201	2114	45	)	)	-RRB-
cord-022561-rv5j1201	2114	46	severe	severe	JJ
cord-022561-rv5j1201	2114	47	bone	bone	NN
cord-022561-rv5j1201	2114	48	marrow	marrow	NN
cord-022561-rv5j1201	2114	49	failure	failure	NN
cord-022561-rv5j1201	2114	50	;	;	,
cord-022561-rv5j1201	2114	51	(	(	-LRB-
cord-022561-rv5j1201	2114	52	2	2	LS
cord-022561-rv5j1201	2114	53	)	)	-RRB-
cord-022561-rv5j1201	2114	54	myelostimulation	myelostimulation	NN
cord-022561-rv5j1201	2114	55	;	;	,
cord-022561-rv5j1201	2114	56	(	(	-LRB-
cord-022561-rv5j1201	2114	57	3	3	LS
cord-022561-rv5j1201	2114	58	)	)	-RRB-
cord-022561-rv5j1201	2114	59	tissue	tissue	NN
cord-022561-rv5j1201	2114	60	inflammation	inflammation	NN
cord-022561-rv5j1201	2114	61	,	,	,
cord-022561-rv5j1201	2114	62	injury	injury	NN
cord-022561-rv5j1201	2114	63	,	,	,
cord-022561-rv5j1201	2114	64	and	and	CC
cord-022561-rv5j1201	2114	65	repair	repair	NN
cord-022561-rv5j1201	2114	66	;	;	:
cord-022561-rv5j1201	2114	67	and	and	CC
cord-022561-rv5j1201	2114	68	(	(	-LRB-
cord-022561-rv5j1201	2114	69	4	4	LS
cord-022561-rv5j1201	2114	70	)	)	-RRB-
cord-022561-rv5j1201	2114	71	abnormal	abnormal	JJ
cord-022561-rv5j1201	2114	72	chemokine	chemokine	NN
cord-022561-rv5j1201	2114	73	production	production	NN
cord-022561-rv5j1201	2114	74	.	.	.
cord-022561-rv5j1201	2115	1	Because	because	IN
cord-022561-rv5j1201	2115	2	splenic	splenic	JJ
cord-022561-rv5j1201	2115	3	EMH	EMH	NNP
cord-022561-rv5j1201	2115	4	is	be	VBZ
cord-022561-rv5j1201	2115	5	often	often	RB
cord-022561-rv5j1201	2115	6	observed	observe	VBN
cord-022561-rv5j1201	2115	7	in	in	IN
cord-022561-rv5j1201	2115	8	animals	animal	NNS
cord-022561-rv5j1201	2115	9	without	without	IN
cord-022561-rv5j1201	2115	10	obvious	obvious	JJ
cord-022561-rv5j1201	2115	11	hematologic	hematologic	JJ
cord-022561-rv5j1201	2115	12	abnormalities	abnormality	NNS
cord-022561-rv5j1201	2115	13	,	,	,
cord-022561-rv5j1201	2115	14	tissue	tissue	NN
cord-022561-rv5j1201	2115	15	inflammation	inflammation	NN
cord-022561-rv5j1201	2115	16	,	,	,
cord-022561-rv5j1201	2115	17	injury	injury	NN
cord-022561-rv5j1201	2115	18	,	,	,
cord-022561-rv5j1201	2115	19	and	and	CC
cord-022561-rv5j1201	2115	20	repair	repair	NN
cord-022561-rv5j1201	2115	21	is	be	VBZ
cord-022561-rv5j1201	2115	22	the	the	DT
cord-022561-rv5j1201	2115	23	most	most	RBS
cord-022561-rv5j1201	2115	24	likely	likely	JJ
cord-022561-rv5j1201	2115	25	mechanism	mechanism	NN
cord-022561-rv5j1201	2115	26	of	of	IN
cord-022561-rv5j1201	2115	27	EMH	EMH	NNP
cord-022561-rv5j1201	2115	28	in	in	IN
cord-022561-rv5j1201	2115	29	this	this	DT
cord-022561-rv5j1201	2115	30	organ	organ	NN
cord-022561-rv5j1201	2115	31	.	.	.
cord-022561-rv5j1201	2116	1	In	in	IN
cord-022561-rv5j1201	2116	2	dogs	dog	NNS
cord-022561-rv5j1201	2116	3	and	and	CC
cord-022561-rv5j1201	2116	4	cats	cat	NNS
cord-022561-rv5j1201	2116	5	EMH	EMH	NNP
cord-022561-rv5j1201	2116	6	occurs	occur	VBZ
cord-022561-rv5j1201	2116	7	most	most	RBS
cord-022561-rv5j1201	2116	8	frequently	frequently	RB
cord-022561-rv5j1201	2116	9	with	with	IN
cord-022561-rv5j1201	2116	10	degenerative	degenerative	JJ
cord-022561-rv5j1201	2116	11	and	and	CC
cord-022561-rv5j1201	2116	12	inflammatory	inflammatory	JJ
cord-022561-rv5j1201	2116	13	disorders	disorder	NNS
cord-022561-rv5j1201	2116	14	,	,	,
cord-022561-rv5j1201	2116	15	such	such	JJ
cord-022561-rv5j1201	2116	16	as	as	IN
cord-022561-rv5j1201	2116	17	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	2116	18	nodular	nodular	JJ
cord-022561-rv5j1201	2116	19	hyperplasia	hyperplasia	NN
cord-022561-rv5j1201	2116	20	,	,	,
cord-022561-rv5j1201	2116	21	hematomas	hematoma	NNS
cord-022561-rv5j1201	2116	22	,	,	,
cord-022561-rv5j1201	2116	23	thrombi	thrombi	NNP
cord-022561-rv5j1201	2116	24	,	,	,
cord-022561-rv5j1201	2116	25	histiocytic	histiocytic	JJ
cord-022561-rv5j1201	2116	26	hyperplasia	hyperplasia	NN
cord-022561-rv5j1201	2116	27	,	,	,
cord-022561-rv5j1201	2116	28	inflammation	inflammation	NN
cord-022561-rv5j1201	2116	29	(	(	-LRB-
cord-022561-rv5j1201	2116	30	e.g.	e.g.	RB
cord-022561-rv5j1201	2116	31	,	,	,
cord-022561-rv5j1201	2116	32	fungal	fungal	JJ
cord-022561-rv5j1201	2116	33	splenitis	splenitis	NNP
cord-022561-rv5j1201	2116	34	)	)	-RRB-
cord-022561-rv5j1201	2116	35	,	,	,
cord-022561-rv5j1201	2116	36	and	and	CC
cord-022561-rv5j1201	2116	37	neoplasia	neoplasia	NN
cord-022561-rv5j1201	2116	38	.	.	.
cord-022561-rv5j1201	2117	1	EMH	EMH	NNP
cord-022561-rv5j1201	2117	2	in	in	IN
cord-022561-rv5j1201	2117	3	multiple	multiple	JJ
cord-022561-rv5j1201	2117	4	tissues	tissue	NNS
cord-022561-rv5j1201	2117	5	may	may	MD
cord-022561-rv5j1201	2117	6	be	be	VB
cord-022561-rv5j1201	2117	7	observed	observe	VBN
cord-022561-rv5j1201	2117	8	in	in	IN
cord-022561-rv5j1201	2117	9	chronic	chronic	JJ
cord-022561-rv5j1201	2117	10	cardiovascular	cardiovascular	JJ
cord-022561-rv5j1201	2117	11	or	or	CC
cord-022561-rv5j1201	2117	12	respiratory	respiratory	JJ
cord-022561-rv5j1201	2117	13	conditions	condition	NNS
cord-022561-rv5j1201	2117	14	,	,	,
cord-022561-rv5j1201	2117	15	chronic	chronic	JJ
cord-022561-rv5j1201	2117	16	anemia	anemia	NN
cord-022561-rv5j1201	2117	17	,	,	,
cord-022561-rv5j1201	2117	18	or	or	CC
cord-022561-rv5j1201	2117	19	chronic	chronic	JJ
cord-022561-rv5j1201	2117	20	suppurative	suppurative	JJ
cord-022561-rv5j1201	2117	21	diseases	disease	NNS
cord-022561-rv5j1201	2117	22	in	in	IN
cord-022561-rv5j1201	2117	23	which	which	WDT
cord-022561-rv5j1201	2117	24	there	there	EX
cord-022561-rv5j1201	2117	25	is	be	VBZ
cord-022561-rv5j1201	2117	26	an	an	DT
cord-022561-rv5j1201	2117	27	excessive	excessive	JJ
cord-022561-rv5j1201	2117	28	tissue	tissue	NN
cord-022561-rv5j1201	2117	29	demand	demand	NN
cord-022561-rv5j1201	2117	30	for	for	IN
cord-022561-rv5j1201	2117	31	neutrophils	neutrophil	NNS
cord-022561-rv5j1201	2117	32	that	that	WDT
cord-022561-rv5j1201	2117	33	exceeds	exceed	VBZ
cord-022561-rv5j1201	2117	34	the	the	DT
cord-022561-rv5j1201	2117	35	supply	supply	NN
cord-022561-rv5j1201	2117	36	available	available	JJ
cord-022561-rv5j1201	2117	37	from	from	IN
cord-022561-rv5j1201	2117	38	the	the	DT
cord-022561-rv5j1201	2117	39	marrow	marrow	NN
cord-022561-rv5j1201	2117	40	(	(	-LRB-
cord-022561-rv5j1201	2117	41	e.g.	e.g.	RB
cord-022561-rv5j1201	2117	42	,	,	,
cord-022561-rv5j1201	2117	43	canine	canine	JJ
cord-022561-rv5j1201	2117	44	pyometra	pyometra	NN
cord-022561-rv5j1201	2117	45	)	)	-RRB-
cord-022561-rv5j1201	2117	46	.	.	.
cord-022561-rv5j1201	2118	1	Primary	Primary	NNP
cord-022561-rv5j1201	2118	2	Neoplasms	Neoplasms	NNP
cord-022561-rv5j1201	2118	3	.	.	.
cord-022561-rv5j1201	2119	1	Primary	primary	JJ
cord-022561-rv5j1201	2119	2	neoplastic	neoplastic	JJ
cord-022561-rv5j1201	2119	3	diseases	disease	NNS
cord-022561-rv5j1201	2119	4	of	of	IN
cord-022561-rv5j1201	2119	5	the	the	DT
cord-022561-rv5j1201	2119	6	spleen	spleen	NNS
cord-022561-rv5j1201	2119	7	arise	arise	VBP
cord-022561-rv5j1201	2119	8	from	from	IN
cord-022561-rv5j1201	2119	9	cell	cell	NN
cord-022561-rv5j1201	2119	10	populations	population	NNS
cord-022561-rv5j1201	2119	11	that	that	WDT
cord-022561-rv5j1201	2119	12	normally	normally	RB
cord-022561-rv5j1201	2119	13	exist	exist	VBP
cord-022561-rv5j1201	2119	14	in	in	IN
cord-022561-rv5j1201	2119	15	the	the	DT
cord-022561-rv5j1201	2119	16	spleen	spleen	NN
cord-022561-rv5j1201	2119	17	and	and	CC
cord-022561-rv5j1201	2119	18	include	include	VBP
cord-022561-rv5j1201	2119	19	hematopoietic	hematopoietic	JJ
cord-022561-rv5j1201	2119	20	components	component	NNS
cord-022561-rv5j1201	2119	21	,	,	,
cord-022561-rv5j1201	2119	22	such	such	JJ
cord-022561-rv5j1201	2119	23	as	as	IN
cord-022561-rv5j1201	2119	24	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	2119	25	,	,	,
cord-022561-rv5j1201	2119	26	mast	mast	NN
cord-022561-rv5j1201	2119	27	cells	cell	NNS
cord-022561-rv5j1201	2119	28	,	,	,
cord-022561-rv5j1201	2119	29	and	and	CC
cord-022561-rv5j1201	2119	30	macrophages	macrophage	NNS
cord-022561-rv5j1201	2119	31	,	,	,
cord-022561-rv5j1201	2119	32	and	and	CC
cord-022561-rv5j1201	2119	33	stromal	stromal	JJ
cord-022561-rv5j1201	2119	34	cells	cell	NNS
cord-022561-rv5j1201	2119	35	,	,	,
cord-022561-rv5j1201	2119	36	such	such	JJ
cord-022561-rv5j1201	2119	37	as	as	IN
cord-022561-rv5j1201	2119	38	fibroblasts	fibroblast	NNS
cord-022561-rv5j1201	2119	39	,	,	,
cord-022561-rv5j1201	2119	40	smooth	smooth	JJ
cord-022561-rv5j1201	2119	41	muscle	muscle	NN
cord-022561-rv5j1201	2119	42	,	,	,
cord-022561-rv5j1201	2119	43	and	and	CC
cord-022561-rv5j1201	2119	44	endothelium	endothelium	NN
cord-022561-rv5j1201	2119	45	.	.	.
cord-022561-rv5j1201	2120	1	The	the	DT
cord-022561-rv5j1201	2120	2	primary	primary	JJ
cord-022561-rv5j1201	2120	3	neoplasms	neoplasm	NNS
cord-022561-rv5j1201	2120	4	that	that	WDT
cord-022561-rv5j1201	2120	5	result	result	VBP
cord-022561-rv5j1201	2120	6	in	in	IN
cord-022561-rv5j1201	2120	7	diffuse	diffuse	JJ
cord-022561-rv5j1201	2120	8	splenomegaly	splenomegaly	NN
cord-022561-rv5j1201	2120	9	are	be	VBP
cord-022561-rv5j1201	2120	10	the	the	DT
cord-022561-rv5j1201	2120	11	round	round	JJ
cord-022561-rv5j1201	2120	12	cell	cell	NN
cord-022561-rv5j1201	2120	13	tumors	tumor	NNS
cord-022561-rv5j1201	2120	14	,	,	,
cord-022561-rv5j1201	2120	15	including	include	VBG
cord-022561-rv5j1201	2120	16	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2120	17	(	(	-LRB-
cord-022561-rv5j1201	2120	18	Fig	Fig	NNP
cord-022561-rv5j1201	2120	19	.	.	.
cord-022561-rv5j1201	2120	20	13	13	CD
cord-022561-rv5j1201	2120	21	-	-	SYM
cord-022561-rv5j1201	2120	22	60	60	CD
cord-022561-rv5j1201	2120	23	)	)	-RRB-
cord-022561-rv5j1201	2120	24	,	,	,
cord-022561-rv5j1201	2120	25	leukemia	leukemia	NN
cord-022561-rv5j1201	2120	26	,	,	,
cord-022561-rv5j1201	2120	27	visceral	visceral	JJ
cord-022561-rv5j1201	2120	28	mast	mast	JJ
cord-022561-rv5j1201	2120	29	cell	cell	NN
cord-022561-rv5j1201	2120	30	tumor	tumor	NN
cord-022561-rv5j1201	2120	31	,	,	,
cord-022561-rv5j1201	2120	32	and	and	CC
cord-022561-rv5j1201	2120	33	histiocytic	histiocytic	JJ
cord-022561-rv5j1201	2120	34	sarcoma	sarcoma	NN
cord-022561-rv5j1201	2120	35	.	.	.
cord-022561-rv5j1201	2121	1	It	-PRON-	PRP
cord-022561-rv5j1201	2121	2	is	be	VBZ
cord-022561-rv5j1201	2121	3	important	important	JJ
cord-022561-rv5j1201	2121	4	to	to	TO
cord-022561-rv5j1201	2121	5	note	note	VB
cord-022561-rv5j1201	2121	6	that	that	IN
cord-022561-rv5j1201	2121	7	all	all	DT
cord-022561-rv5j1201	2121	8	of	of	IN
cord-022561-rv5j1201	2121	9	these	these	DT
cord-022561-rv5j1201	2121	10	types	type	NNS
cord-022561-rv5j1201	2121	11	of	of	IN
cord-022561-rv5j1201	2121	12	neoplasms	neoplasm	NNS
cord-022561-rv5j1201	2121	13	can	can	MD
cord-022561-rv5j1201	2121	14	produce	produce	VB
cord-022561-rv5j1201	2121	15	nodular	nodular	JJ
cord-022561-rv5j1201	2121	16	lesions	lesion	NNS
cord-022561-rv5j1201	2121	17	instead	instead	RB
cord-022561-rv5j1201	2121	18	of	of	IN
cord-022561-rv5j1201	2121	19	-	-	:
cord-022561-rv5j1201	2121	20	or	or	CC
cord-022561-rv5j1201	2121	21	along	along	IN
cord-022561-rv5j1201	2121	22	with	with	IN
cord-022561-rv5j1201	2121	23	-	-	HYPH
cord-022561-rv5j1201	2121	24	a	a	DT
cord-022561-rv5j1201	2121	25	diffusely	diffusely	RB
cord-022561-rv5j1201	2121	26	enlarged	enlarge	VBN
cord-022561-rv5j1201	2121	27	spleen	spleen	NNS
cord-022561-rv5j1201	2121	28	.	.	.
cord-022561-rv5j1201	2122	1	The	the	DT
cord-022561-rv5j1201	2122	2	different	different	JJ
cord-022561-rv5j1201	2122	3	types	type	NNS
cord-022561-rv5j1201	2122	4	of	of	IN
cord-022561-rv5j1201	2122	5	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2122	6	in	in	IN
cord-022561-rv5j1201	2122	7	domestic	domestic	JJ
cord-022561-rv5j1201	2122	8	animals	animal	NNS
cord-022561-rv5j1201	2122	9	are	be	VBP
cord-022561-rv5j1201	2122	10	discussed	discuss	VBN
cord-022561-rv5j1201	2122	11	in	in	IN
cord-022561-rv5j1201	2122	12	the	the	DT
cord-022561-rv5j1201	2122	13	section	section	NN
cord-022561-rv5j1201	2122	14	on	on	IN
cord-022561-rv5j1201	2122	15	Hematopoietic	Hematopoietic	NNP
cord-022561-rv5j1201	2122	16	Neoplasia	Neoplasia	NNP
cord-022561-rv5j1201	2122	17	.	.	.
cord-022561-rv5j1201	2123	1	Secondary	secondary	JJ
cord-022561-rv5j1201	2123	2	neoplasms	neoplasm	NNS
cord-022561-rv5j1201	2123	3	of	of	IN
cord-022561-rv5j1201	2123	4	the	the	DT
cord-022561-rv5j1201	2123	5	spleen	spleen	NNS
cord-022561-rv5j1201	2123	6	are	be	VBP
cord-022561-rv5j1201	2123	7	due	due	JJ
cord-022561-rv5j1201	2123	8	to	to	IN
cord-022561-rv5j1201	2123	9	metastatic	metastatic	JJ
cord-022561-rv5j1201	2123	10	spread	spread	NN
cord-022561-rv5j1201	2123	11	and	and	CC
cord-022561-rv5j1201	2123	12	most	most	RBS
cord-022561-rv5j1201	2123	13	often	often	RB
cord-022561-rv5j1201	2123	14	form	form	VBP
cord-022561-rv5j1201	2123	15	nodules	nodule	NNS
cord-022561-rv5j1201	2123	16	in	in	IN
cord-022561-rv5j1201	2123	17	the	the	DT
cord-022561-rv5j1201	2123	18	spleen	spleen	NN
cord-022561-rv5j1201	2123	19	,	,	,
cord-022561-rv5j1201	2123	20	not	not	RB
cord-022561-rv5j1201	2123	21	a	a	DT
cord-022561-rv5j1201	2123	22	uniform	uniform	JJ
cord-022561-rv5j1201	2123	23	splenomegaly	splenomegaly	NN
cord-022561-rv5j1201	2123	24	.	.	.
cord-022561-rv5j1201	2124	1	Amyloid	amyloid	NN
cord-022561-rv5j1201	2124	2	.	.	.
cord-022561-rv5j1201	2125	1	The	the	DT
cord-022561-rv5j1201	2125	2	accumulation	accumulation	NN
cord-022561-rv5j1201	2125	3	of	of	IN
cord-022561-rv5j1201	2125	4	amyloid	amyloid	NN
cord-022561-rv5j1201	2125	5	in	in	IN
cord-022561-rv5j1201	2125	6	the	the	DT
cord-022561-rv5j1201	2125	7	spleen	spleen	NN
cord-022561-rv5j1201	2125	8	may	may	MD
cord-022561-rv5j1201	2125	9	occur	occur	VB
cord-022561-rv5j1201	2125	10	with	with	IN
cord-022561-rv5j1201	2125	11	primary	primary	JJ
cord-022561-rv5j1201	2125	12	(	(	-LRB-
cord-022561-rv5j1201	2125	13	AL	AL	NNP
cord-022561-rv5j1201	2125	14	)	)	-RRB-
cord-022561-rv5j1201	2125	15	or	or	CC
cord-022561-rv5j1201	2126	1	secondary	secondary	JJ
cord-022561-rv5j1201	2126	2	(	(	-LRB-
cord-022561-rv5j1201	2126	3	AA	AA	NNP
cord-022561-rv5j1201	2126	4	)	)	-RRB-
cord-022561-rv5j1201	2126	5	amyloidosis	amyloidosis	NN
cord-022561-rv5j1201	2126	6	(	(	-LRB-
cord-022561-rv5j1201	2126	7	see	see	VB
cord-022561-rv5j1201	2126	8	Chapters	chapter	NNS
cord-022561-rv5j1201	2126	9	1	1	CD
cord-022561-rv5j1201	2126	10	and	and	CC
cord-022561-rv5j1201	2126	11	5	5	CD
cord-022561-rv5j1201	2126	12	)	)	-RRB-
cord-022561-rv5j1201	2126	13	.	.	.
cord-022561-rv5j1201	2127	1	Rarely	rarely	RB
cord-022561-rv5j1201	2127	2	,	,	,
cord-022561-rv5j1201	2127	3	severe	severe	JJ
cord-022561-rv5j1201	2127	4	amyloid	amyloid	NN
cord-022561-rv5j1201	2127	5	accumulation	accumulation	NN
cord-022561-rv5j1201	2127	6	may	may	MD
cord-022561-rv5j1201	2127	7	cause	cause	VB
cord-022561-rv5j1201	2127	8	uniform	uniform	JJ
cord-022561-rv5j1201	2127	9	splenomegaly	splenomegaly	NN
cord-022561-rv5j1201	2127	10	(	(	-LRB-
cord-022561-rv5j1201	2127	11	Fig	Fig	NNP
cord-022561-rv5j1201	2127	12	.	.	.
cord-022561-rv5j1201	2127	13	13	13	CD
cord-022561-rv5j1201	2127	14	-	-	SYM
cord-022561-rv5j1201	2127	15	61	61	CD
cord-022561-rv5j1201	2127	16	)	)	-RRB-
cord-022561-rv5j1201	2127	17	,	,	,
cord-022561-rv5j1201	2127	18	in	in	IN
cord-022561-rv5j1201	2127	19	which	which	WDT
cord-022561-rv5j1201	2127	20	the	the	DT
cord-022561-rv5j1201	2127	21	spleen	spleen	NN
cord-022561-rv5j1201	2127	22	is	be	VBZ
cord-022561-rv5j1201	2127	23	firm	firm	JJ
cord-022561-rv5j1201	2127	24	,	,	,
cord-022561-rv5j1201	2127	25	rubbery	rubbery	JJ
cord-022561-rv5j1201	2127	26	to	to	IN
cord-022561-rv5j1201	2127	27	waxy	waxy	JJ
cord-022561-rv5j1201	2127	28	,	,	,
cord-022561-rv5j1201	2127	29	and	and	CC
cord-022561-rv5j1201	2127	30	light	light	JJ
cord-022561-rv5j1201	2127	31	brown	brown	NNP
cord-022561-rv5j1201	2127	32	to	to	IN
cord-022561-rv5j1201	2127	33	orange	orange	NNP
cord-022561-rv5j1201	2127	34	.	.	.
cord-022561-rv5j1201	2128	1	Microscopically	microscopically	RB
cord-022561-rv5j1201	2128	2	,	,	,
cord-022561-rv5j1201	2128	3	amyloid	amyloid	NN
cord-022561-rv5j1201	2128	4	is	be	VBZ
cord-022561-rv5j1201	2128	5	usually	usually	RB
cord-022561-rv5j1201	2128	6	in	in	IN
cord-022561-rv5j1201	2128	7	the	the	DT
cord-022561-rv5j1201	2128	8	splenic	splenic	JJ
cord-022561-rv5j1201	2128	9	follicles	follicle	NNS
cord-022561-rv5j1201	2128	10	,	,	,
cord-022561-rv5j1201	2128	11	which	which	WDT
cord-022561-rv5j1201	2128	12	if	if	IN
cord-022561-rv5j1201	2128	13	large	large	JJ
cord-022561-rv5j1201	2128	14	enough	enough	RB
cord-022561-rv5j1201	2128	15	,	,	,
cord-022561-rv5j1201	2128	16	are	be	VBP
cord-022561-rv5j1201	2128	17	grossly	grossly	RB
cord-022561-rv5j1201	2128	18	visible	visible	JJ
cord-022561-rv5j1201	2128	19	as	as	RB
cord-022561-rv5j1201	2128	20	approximately	approximately	RB
cord-022561-rv5j1201	2128	21	2-mm	2-mm	CD
cord-022561-rv5j1201	2128	22	-	-	HYPH
cord-022561-rv5j1201	2128	23	diameter	diameter	NN
cord-022561-rv5j1201	2128	24	gray	gray	JJ
cord-022561-rv5j1201	2128	25	nodules	nodule	NNS
cord-022561-rv5j1201	2128	26	.	.	.
cord-022561-rv5j1201	2129	1	Amyloid	amyloid	NN
cord-022561-rv5j1201	2129	2	deposition	deposition	NN
cord-022561-rv5j1201	2129	3	can	can	MD
cord-022561-rv5j1201	2129	4	also	also	RB
cord-022561-rv5j1201	2129	5	be	be	VB
cord-022561-rv5j1201	2129	6	seen	see	VBN
cord-022561-rv5j1201	2129	7	within	within	IN
cord-022561-rv5j1201	2129	8	the	the	DT
cord-022561-rv5j1201	2129	9	walls	wall	NNS
cord-022561-rv5j1201	2129	10	of	of	IN
cord-022561-rv5j1201	2129	11	splenic	splenic	JJ
cord-022561-rv5j1201	2129	12	veins	vein	NNS
cord-022561-rv5j1201	2129	13	and	and	CC
cord-022561-rv5j1201	2129	14	arterioles	arteriole	NNS
cord-022561-rv5j1201	2129	15	.	.	.
cord-022561-rv5j1201	2130	1	Plasma	plasma	NN
cord-022561-rv5j1201	2130	2	cells	cell	NNS
cord-022561-rv5j1201	2130	3	tumors	tumor	NNS
cord-022561-rv5j1201	2130	4	within	within	IN
cord-022561-rv5j1201	2130	5	the	the	DT
cord-022561-rv5j1201	2130	6	spleen	spleen	NN
cord-022561-rv5j1201	2130	7	may	may	MD
cord-022561-rv5j1201	2130	8	also	also	RB
cord-022561-rv5j1201	2130	9	be	be	VB
cord-022561-rv5j1201	2130	10	associated	associate	VBN
cord-022561-rv5j1201	2130	11	with	with	IN
cord-022561-rv5j1201	2130	12	amyloid	amyloid	NN
cord-022561-rv5j1201	2130	13	(	(	-LRB-
cord-022561-rv5j1201	2130	14	AL	AL	NNP
cord-022561-rv5j1201	2130	15	)	)	-RRB-
cord-022561-rv5j1201	2130	16	deposits	deposit	NNS
cord-022561-rv5j1201	2130	17	.	.	.
cord-022561-rv5j1201	2131	1	Lysosomal	Lysosomal	NNP
cord-022561-rv5j1201	2131	2	Storage	Storage	NNP
cord-022561-rv5j1201	2131	3	Diseases	Diseases	NNPS
cord-022561-rv5j1201	2131	4	.	.	.
cord-022561-rv5j1201	2132	1	Storage	storage	NN
cord-022561-rv5j1201	2132	2	diseases	disease	NNS
cord-022561-rv5j1201	2132	3	are	be	VBP
cord-022561-rv5j1201	2132	4	a	a	DT
cord-022561-rv5j1201	2132	5	heterogeneous	heterogeneous	JJ
cord-022561-rv5j1201	2132	6	group	group	NN
cord-022561-rv5j1201	2132	7	of	of	IN
cord-022561-rv5j1201	2132	8	inherited	inherit	VBN
cord-022561-rv5j1201	2132	9	defects	defect	NNS
cord-022561-rv5j1201	2132	10	in	in	IN
cord-022561-rv5j1201	2132	11	metabolism	metabolism	NN
cord-022561-rv5j1201	2132	12	characterized	characterize	VBN
cord-022561-rv5j1201	2132	13	by	by	IN
cord-022561-rv5j1201	2132	14	accumulation	accumulation	NN
cord-022561-rv5j1201	2132	15	of	of	IN
cord-022561-rv5j1201	2132	16	storage	storage	NN
cord-022561-rv5j1201	2132	17	material	material	NN
cord-022561-rv5j1201	2132	18	within	within	IN
cord-022561-rv5j1201	2132	19	the	the	DT
cord-022561-rv5j1201	2132	20	cell	cell	NN
cord-022561-rv5j1201	2132	21	(	(	-LRB-
cord-022561-rv5j1201	2132	22	lysosomes	lysosome	NNS
cord-022561-rv5j1201	2132	23	)	)	-RRB-
cord-022561-rv5j1201	2132	24	.	.	.
cord-022561-rv5j1201	2133	1	Genetic	genetic	JJ
cord-022561-rv5j1201	2133	2	defects	defect	NNS
cord-022561-rv5j1201	2133	3	,	,	,
cord-022561-rv5j1201	2133	4	which	which	WDT
cord-022561-rv5j1201	2133	5	result	result	VBP
cord-022561-rv5j1201	2133	6	in	in	IN
cord-022561-rv5j1201	2133	7	the	the	DT
cord-022561-rv5j1201	2133	8	absence	absence	NN
cord-022561-rv5j1201	2133	9	of	of	IN
cord-022561-rv5j1201	2133	10	an	an	DT
cord-022561-rv5j1201	2133	11	enzyme	enzyme	NN
cord-022561-rv5j1201	2133	12	,	,	,
cord-022561-rv5j1201	2133	13	the	the	DT
cord-022561-rv5j1201	2133	14	synthesis	synthesis	NN
cord-022561-rv5j1201	2133	15	of	of	IN
cord-022561-rv5j1201	2133	16	a	a	DT
cord-022561-rv5j1201	2133	17	catalytically	catalytically	RB
cord-022561-rv5j1201	2133	18	inactive	inactive	JJ
cord-022561-rv5j1201	2133	19	enzyme	enzyme	NN
cord-022561-rv5j1201	2133	20	,	,	,
cord-022561-rv5j1201	2133	21	the	the	DT
cord-022561-rv5j1201	2133	22	lack	lack	NN
cord-022561-rv5j1201	2133	23	of	of	IN
cord-022561-rv5j1201	2133	24	activator	activator	NN
cord-022561-rv5j1201	2133	25	proteins	protein	NNS
cord-022561-rv5j1201	2133	26	,	,	,
cord-022561-rv5j1201	2133	27	or	or	CC
cord-022561-rv5j1201	2133	28	a	a	DT
cord-022561-rv5j1201	2133	29	defect	defect	NN
cord-022561-rv5j1201	2133	30	in	in	IN
cord-022561-rv5j1201	2133	31	posttranslational	posttranslational	JJ
cord-022561-rv5j1201	2133	32	processing	processing	NN
cord-022561-rv5j1201	2133	33	,	,	,
cord-022561-rv5j1201	2133	34	can	can	MD
cord-022561-rv5j1201	2133	35	lead	lead	VB
cord-022561-rv5j1201	2133	36	to	to	IN
cord-022561-rv5j1201	2133	37	a	a	DT
cord-022561-rv5j1201	2133	38	storage	storage	NN
cord-022561-rv5j1201	2133	39	disease	disease	NN
cord-022561-rv5j1201	2133	40	.	.	.
cord-022561-rv5j1201	2134	1	Acquired	acquire	VBN
cord-022561-rv5j1201	2134	2	storage	storage	NN
cord-022561-rv5j1201	2134	3	diseases	disease	NNS
cord-022561-rv5j1201	2134	4	are	be	VBP
cord-022561-rv5j1201	2134	5	caused	cause	VBN
cord-022561-rv5j1201	2134	6	by	by	IN
cord-022561-rv5j1201	2134	7	exogenous	exogenous	JJ
cord-022561-rv5j1201	2134	8	toxins	toxin	NNS
cord-022561-rv5j1201	2134	9	,	,	,
cord-022561-rv5j1201	2134	10	most	most	RBS
cord-022561-rv5j1201	2134	11	often	often	RB
cord-022561-rv5j1201	2134	12	plants	plant	NNS
cord-022561-rv5j1201	2134	13	that	that	WDT
cord-022561-rv5j1201	2134	14	inhibit	inhibit	VBP
cord-022561-rv5j1201	2134	15	a	a	DT
cord-022561-rv5j1201	2134	16	particular	particular	JJ
cord-022561-rv5j1201	2134	17	lysosomal	lysosomal	JJ
cord-022561-rv5j1201	2134	18	enzyme	enzyme	NN
cord-022561-rv5j1201	2134	19	(	(	-LRB-
cord-022561-rv5j1201	2134	20	e.g.	e.g.	RB
cord-022561-rv5j1201	2134	21	,	,	,
cord-022561-rv5j1201	2134	22	swainsonine	swainsonine	JJ
cord-022561-rv5j1201	2134	23	toxicity	toxicity	NN
cord-022561-rv5j1201	2134	24	due	due	IN
cord-022561-rv5j1201	2134	25	to	to	IN
cord-022561-rv5j1201	2134	26	indolizidine	indolizidine	NN
cord-022561-rv5j1201	2134	27	alkaloid	alkaloid	NN
cord-022561-rv5j1201	2134	28	found	find	VBN
cord-022561-rv5j1201	2134	29	in	in	IN
cord-022561-rv5j1201	2134	30	Astragalus	Astragalus	NNP
cord-022561-rv5j1201	2134	31	and	and	CC
cord-022561-rv5j1201	2134	32	Oxytropis	Oxytropis	NNP
cord-022561-rv5j1201	2134	33	plant	plant	NN
cord-022561-rv5j1201	2134	34	spp	spp	NNS
cord-022561-rv5j1201	2134	35	.	.	.
cord-022561-rv5j1201	2134	36	)	)	-RRB-
cord-022561-rv5j1201	2134	37	.	.	.
cord-022561-rv5j1201	2135	1	Storage	storage	NN
cord-022561-rv5j1201	2135	2	diseases	disease	NNS
cord-022561-rv5j1201	2135	3	typically	typically	RB
cord-022561-rv5j1201	2135	4	occur	occur	VBP
cord-022561-rv5j1201	2135	5	 	 	_SP
cord-022561-rv5j1201	2135	6	diagnosis	diagnosis	NN
cord-022561-rv5j1201	2135	7	,	,	,
cord-022561-rv5j1201	2135	8	it	-PRON-	PRP
cord-022561-rv5j1201	2135	9	may	may	MD
cord-022561-rv5j1201	2135	10	be	be	VB
cord-022561-rv5j1201	2135	11	difficult	difficult	JJ
cord-022561-rv5j1201	2135	12	(	(	-LRB-
cord-022561-rv5j1201	2135	13	and	and	CC
cord-022561-rv5j1201	2135	14	futile	futile	JJ
cord-022561-rv5j1201	2135	15	)	)	-RRB-
cord-022561-rv5j1201	2135	16	to	to	TO
cord-022561-rv5j1201	2135	17	determine	determine	VB
cord-022561-rv5j1201	2135	18	the	the	DT
cord-022561-rv5j1201	2135	19	primary	primary	JJ
cord-022561-rv5j1201	2135	20	site	site	NN
cord-022561-rv5j1201	2135	21	.	.	.
cord-022561-rv5j1201	2136	1	Histologically	Histologically	NNP
cord-022561-rv5j1201	2136	2	,	,	,
cord-022561-rv5j1201	2136	3	hemangiosarcomas	hemangiosarcomas	NNP
cord-022561-rv5j1201	2136	4	are	be	VBP
cord-022561-rv5j1201	2136	5	composed	compose	VBN
cord-022561-rv5j1201	2136	6	of	of	IN
cord-022561-rv5j1201	2136	7	plump	plump	JJ
cord-022561-rv5j1201	2136	8	neoplastic	neoplastic	JJ
cord-022561-rv5j1201	2136	9	endothelial	endothelial	JJ
cord-022561-rv5j1201	2136	10	cells	cell	NNS
cord-022561-rv5j1201	2136	11	,	,	,
cord-022561-rv5j1201	2136	12	which	which	WDT
cord-022561-rv5j1201	2136	13	wrap	wrap	VBP
cord-022561-rv5j1201	2136	14	around	around	RP
cord-022561-rv5j1201	2136	15	stroma	stroma	NN
cord-022561-rv5j1201	2136	16	to	to	TO
cord-022561-rv5j1201	2136	17	form	form	NN
cord-022561-rv5j1201	2136	18	haphazardly	haphazardly	RB
cord-022561-rv5j1201	2136	19	arranged	arrange	VBN
cord-022561-rv5j1201	2136	20	and	and	CC
cord-022561-rv5j1201	2136	21	poorly	poorly	RB
cord-022561-rv5j1201	2136	22	defined	define	VBN
cord-022561-rv5j1201	2136	23	blood	blood	NN
cord-022561-rv5j1201	2136	24	-	-	HYPH
cord-022561-rv5j1201	2136	25	filled	fill	VBN
cord-022561-rv5j1201	2136	26	vascular	vascular	JJ
cord-022561-rv5j1201	2136	27	spaces	space	NNS
cord-022561-rv5j1201	2136	28	(	(	-LRB-
cord-022561-rv5j1201	2136	29	Fig	Fig	NNP
cord-022561-rv5j1201	2136	30	.	.	.
cord-022561-rv5j1201	2136	31	13	13	CD
cord-022561-rv5j1201	2136	32	-	-	SYM
cord-022561-rv5j1201	2136	33	66	66	CD
cord-022561-rv5j1201	2136	34	)	)	-RRB-
cord-022561-rv5j1201	2136	35	.	.	.
cord-022561-rv5j1201	2137	1	Splenic	Splenic	NNP
cord-022561-rv5j1201	2137	2	Nodules	Nodules	NNP
cord-022561-rv5j1201	2137	3	with	with	IN
cord-022561-rv5j1201	2137	4	a	a	DT
cord-022561-rv5j1201	2137	5	Firm	Firm	NNP
cord-022561-rv5j1201	2137	6	Consistency	Consistency	NNP
cord-022561-rv5j1201	2137	7	.	.	.
cord-022561-rv5j1201	2138	1	The	the	DT
cord-022561-rv5j1201	2138	2	most	most	RBS
cord-022561-rv5j1201	2138	3	common	common	JJ
cord-022561-rv5j1201	2138	4	disorders	disorder	NNS
cord-022561-rv5j1201	2138	5	of	of	IN
cord-022561-rv5j1201	2138	6	the	the	DT
cord-022561-rv5j1201	2138	7	spleen	spleen	NN
cord-022561-rv5j1201	2138	8	with	with	IN
cord-022561-rv5j1201	2138	9	firm	firm	JJ
cord-022561-rv5j1201	2138	10	nodules	nodule	NNS
cord-022561-rv5j1201	2138	11	are	be	VBP
cord-022561-rv5j1201	2138	12	(	(	-LRB-
cord-022561-rv5j1201	2138	13	1	1	CD
cord-022561-rv5j1201	2138	14	)	)	-RRB-
cord-022561-rv5j1201	2138	15	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	2138	16	nodular	nodular	JJ
cord-022561-rv5j1201	2138	17	hyperplasia	hyperplasia	NN
cord-022561-rv5j1201	2138	18	,	,	,
cord-022561-rv5j1201	2138	19	(	(	-LRB-
cord-022561-rv5j1201	2138	20	2	2	LS
cord-022561-rv5j1201	2138	21	)	)	-RRB-
cord-022561-rv5j1201	2139	1	complex	complex	JJ
cord-022561-rv5j1201	2139	2	nodular	nodular	JJ
cord-022561-rv5j1201	2139	3	hyperplasia	hyperplasia	NN
cord-022561-rv5j1201	2139	4	,	,	,
cord-022561-rv5j1201	2139	5	(	(	-LRB-
cord-022561-rv5j1201	2139	6	3	3	LS
cord-022561-rv5j1201	2139	7	)	)	-RRB-
cord-022561-rv5j1201	2139	8	primary	primary	JJ
cord-022561-rv5j1201	2139	9	neoplasms	neoplasm	NNS
cord-022561-rv5j1201	2139	10	,	,	,
cord-022561-rv5j1201	2139	11	(	(	-LRB-
cord-022561-rv5j1201	2139	12	4	4	LS
cord-022561-rv5j1201	2139	13	)	)	-RRB-
cord-022561-rv5j1201	2139	14	secondary	secondary	JJ
cord-022561-rv5j1201	2139	15	metastatic	metastatic	JJ
cord-022561-rv5j1201	2139	16	neoplasms	neoplasm	NNS
cord-022561-rv5j1201	2139	17	,	,	,
cord-022561-rv5j1201	2139	18	(	(	-LRB-
cord-022561-rv5j1201	2139	19	5	5	LS
cord-022561-rv5j1201	2139	20	)	)	-RRB-
cord-022561-rv5j1201	2139	21	granulomas	granuloma	NNS
cord-022561-rv5j1201	2139	22	,	,	,
cord-022561-rv5j1201	2139	23	and	and	CC
cord-022561-rv5j1201	2139	24	(	(	-LRB-
cord-022561-rv5j1201	2139	25	6	6	LS
cord-022561-rv5j1201	2139	26	)	)	-RRB-
cord-022561-rv5j1201	2139	27	abscesses	abscess	NNS
cord-022561-rv5j1201	2139	28	.	.	.
cord-022561-rv5j1201	2140	1	Lymphoid	lymphoid	JJ
cord-022561-rv5j1201	2140	2	and	and	CC
cord-022561-rv5j1201	2140	3	Complex	Complex	NNP
cord-022561-rv5j1201	2140	4	Nodular	Nodular	NNP
cord-022561-rv5j1201	2140	5	Hyperplasia	Hyperplasia	NNP
cord-022561-rv5j1201	2140	6	.	.	.
cord-022561-rv5j1201	2141	1	See	see	VB
cord-022561-rv5j1201	2141	2	Lymphoid/	lymphoid/	NN
cord-022561-rv5j1201	2141	3	Lymphatic	Lymphatic	NNP
cord-022561-rv5j1201	2141	4	System	System	NNP
cord-022561-rv5j1201	2141	5	,	,	,
cord-022561-rv5j1201	2141	6	Disorders	Disorders	NNPS
cord-022561-rv5j1201	2141	7	of	of	IN
cord-022561-rv5j1201	2141	8	Dogs	dog	NNS
cord-022561-rv5j1201	2141	9	.	.	.
cord-022561-rv5j1201	2142	1	Primary	Primary	NNP
cord-022561-rv5j1201	2142	2	Neoplasms	Neoplasms	NNP
cord-022561-rv5j1201	2142	3	.	.	.
cord-022561-rv5j1201	2143	1	The	the	DT
cord-022561-rv5j1201	2143	2	primary	primary	JJ
cord-022561-rv5j1201	2143	3	neoplastic	neoplastic	JJ
cord-022561-rv5j1201	2143	4	diseases	disease	NNS
cord-022561-rv5j1201	2143	5	of	of	IN
cord-022561-rv5j1201	2143	6	the	the	DT
cord-022561-rv5j1201	2143	7	spleen	spleen	NNS
cord-022561-rv5j1201	2143	8	that	that	WDT
cord-022561-rv5j1201	2143	9	result	result	VBP
cord-022561-rv5j1201	2143	10	in	in	IN
cord-022561-rv5j1201	2143	11	firm	firm	JJ
cord-022561-rv5j1201	2143	12	nodules	nodule	NNS
cord-022561-rv5j1201	2143	13	include	include	VBP
cord-022561-rv5j1201	2143	14	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2143	15	(	(	-LRB-
cord-022561-rv5j1201	2143	16	multiple	multiple	JJ
cord-022561-rv5j1201	2143	17	subtypes	subtype	NNS
cord-022561-rv5j1201	2143	18	)	)	-RRB-
cord-022561-rv5j1201	2143	19	,	,	,
cord-022561-rv5j1201	2143	20	histiocytic	histiocytic	JJ
cord-022561-rv5j1201	2143	21	sarcoma	sarcoma	NN
cord-022561-rv5j1201	2143	22	,	,	,
cord-022561-rv5j1201	2143	23	leiomyoma	leiomyoma	NNP
cord-022561-rv5j1201	2143	24	,	,	,
cord-022561-rv5j1201	2143	25	leiomyosarcoma	leiomyosarcoma	NNP
cord-022561-rv5j1201	2143	26	,	,	,
cord-022561-rv5j1201	2143	27	fibrosarcoma	fibrosarcoma	NNP
cord-022561-rv5j1201	2143	28	,	,	,
cord-022561-rv5j1201	2143	29	myelolipomas	myelolipomas	NNP
cord-022561-rv5j1201	2143	30	,	,	,
cord-022561-rv5j1201	2143	31	liposarcomas	liposarcomas	NNP
cord-022561-rv5j1201	2143	32	,	,	,
cord-022561-rv5j1201	2143	33	myxosarcomas	myxosarcomas	NNP
cord-022561-rv5j1201	2143	34	,	,	,
cord-022561-rv5j1201	2143	35	undifferentiated	undifferentiated	JJ
cord-022561-rv5j1201	2143	36	pleomorphic	pleomorphic	JJ
cord-022561-rv5j1201	2143	37	sarcomas	sarcoma	NNS
cord-022561-rv5j1201	2143	38	,	,	,
cord-022561-rv5j1201	2143	39	solid	solid	JJ
cord-022561-rv5j1201	2143	40	hemangiosarcomas	hemangiosarcomas	NN
cord-022561-rv5j1201	2143	41	,	,	,
cord-022561-rv5j1201	2143	42	and	and	CC
cord-022561-rv5j1201	2143	43	rare	rare	JJ
cord-022561-rv5j1201	2143	44	reports	report	NNS
cord-022561-rv5j1201	2143	45	of	of	IN
cord-022561-rv5j1201	2143	46	primary	primary	JJ
cord-022561-rv5j1201	2143	47	chondrosarcomas	chondrosarcoma	NNS
cord-022561-rv5j1201	2143	48	.	.	.
cord-022561-rv5j1201	2144	1	These	these	DT
cord-022561-rv5j1201	2144	2	locally	locally	RB
cord-022561-rv5j1201	2144	3	extensive	extensive	JJ
cord-022561-rv5j1201	2144	4	neoplasms	neoplasm	NNS
cord-022561-rv5j1201	2144	5	may	may	MD
cord-022561-rv5j1201	2144	6	be	be	VB
cord-022561-rv5j1201	2144	7	solitary	solitary	JJ
cord-022561-rv5j1201	2144	8	or	or	CC
cord-022561-rv5j1201	2144	9	multiple	multiple	JJ
cord-022561-rv5j1201	2144	10	,	,	,
cord-022561-rv5j1201	2144	11	raised	raise	VBN
cord-022561-rv5j1201	2144	12	above	above	IN
cord-022561-rv5j1201	2144	13	the	the	DT
cord-022561-rv5j1201	2144	14	capsular	capsular	NN
cord-022561-rv5j1201	2144	15	surface	surface	NN
cord-022561-rv5j1201	2144	16	,	,	,
cord-022561-rv5j1201	2144	17	but	but	CC
cord-022561-rv5j1201	2144	18	usually	usually	RB
cord-022561-rv5j1201	2144	19	confined	confine	VBN
cord-022561-rv5j1201	2144	20	by	by	IN
cord-022561-rv5j1201	2144	21	the	the	DT
cord-022561-rv5j1201	2144	22	capsular	capsular	JJ
cord-022561-rv5j1201	2144	23	surface	surface	NN
cord-022561-rv5j1201	2144	24	.	.	.
cord-022561-rv5j1201	2145	1	The	the	DT
cord-022561-rv5j1201	2145	2	consistency	consistency	NN
cord-022561-rv5j1201	2145	3	and	and	CC
cord-022561-rv5j1201	2145	4	cut	cut	NN
cord-022561-rv5j1201	2145	5	surface	surface	NN
cord-022561-rv5j1201	2145	6	appearance	appearance	NN
cord-022561-rv5j1201	2145	7	varies	vary	VBZ
cord-022561-rv5j1201	2145	8	depending	depend	VBG
cord-022561-rv5j1201	2145	9	on	on	IN
cord-022561-rv5j1201	2145	10	the	the	DT
cord-022561-rv5j1201	2145	11	type	type	NN
cord-022561-rv5j1201	2145	12	of	of	IN
cord-022561-rv5j1201	2145	13	neoplasm	neoplasm	NN
cord-022561-rv5j1201	2145	14	;	;	:
cord-022561-rv5j1201	2145	15	spindle	spindle	NN
cord-022561-rv5j1201	2145	16	cell	cell	NN
cord-022561-rv5j1201	2145	17	tumors	tumor	NNS
cord-022561-rv5j1201	2145	18	like	like	IN
cord-022561-rv5j1201	2145	19	leiomyosarcomas	leiomyosarcomas	NNP
cord-022561-rv5j1201	2145	20	and	and	CC
cord-022561-rv5j1201	2145	21	fibrosarcomas	fibrosarcomas	NNP
cord-022561-rv5j1201	2145	22	will	will	MD
cord-022561-rv5j1201	2145	23	be	be	VB
cord-022561-rv5j1201	2145	24	white	white	JJ
cord-022561-rv5j1201	2145	25	and	and	CC
cord-022561-rv5j1201	2145	26	firm	firm	JJ
cord-022561-rv5j1201	2145	27	,	,	,
cord-022561-rv5j1201	2145	28	liposarcomas	liposarcomas	NNP
cord-022561-rv5j1201	2145	29	and	and	CC
cord-022561-rv5j1201	2145	30	myelolipomas	myelolipomas	NNP
cord-022561-rv5j1201	2145	31	are	be	VBP
cord-022561-rv5j1201	2145	32	soft	soft	JJ
cord-022561-rv5j1201	2145	33	and	and	CC
cord-022561-rv5j1201	2145	34	bulging	bulge	VBG
cord-022561-rv5j1201	2145	35	,	,	,
cord-022561-rv5j1201	2145	36	and	and	CC
cord-022561-rv5j1201	2145	37	myxomatous	myxomatous	JJ
cord-022561-rv5j1201	2145	38	neoplasms	neoplasm	NNS
cord-022561-rv5j1201	2145	39	are	be	VBP
cord-022561-rv5j1201	2145	40	gelatinous	gelatinous	JJ
cord-022561-rv5j1201	2145	41	.	.	.
cord-022561-rv5j1201	2146	1	It	-PRON-	PRP
cord-022561-rv5j1201	2146	2	is	be	VBZ
cord-022561-rv5j1201	2146	3	important	important	JJ
cord-022561-rv5j1201	2146	4	to	to	TO
cord-022561-rv5j1201	2146	5	remember	remember	VB
cord-022561-rv5j1201	2146	6	that	that	IN
cord-022561-rv5j1201	2146	7	many	many	JJ
cord-022561-rv5j1201	2146	8	round	round	JJ
cord-022561-rv5j1201	2146	9	cell	cell	NN
cord-022561-rv5j1201	2146	10	neoplasms	neoplasm	NNS
cord-022561-rv5j1201	2146	11	,	,	,
cord-022561-rv5j1201	2146	12	such	such	JJ
cord-022561-rv5j1201	2146	13	as	as	IN
cord-022561-rv5j1201	2146	14	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2146	15	,	,	,
cord-022561-rv5j1201	2146	16	mast	mast	NN
cord-022561-rv5j1201	2146	17	cell	cell	NN
cord-022561-rv5j1201	2146	18	tumors	tumor	NNS
cord-022561-rv5j1201	2146	19	,	,	,
cord-022561-rv5j1201	2146	20	plasma	plasma	NN
cord-022561-rv5j1201	2146	21	cell	cell	NN
cord-022561-rv5j1201	2146	22	tumors	tumor	NNS
cord-022561-rv5j1201	2146	23	,	,	,
cord-022561-rv5j1201	2146	24	myeloid	myeloid	JJ
cord-022561-rv5j1201	2146	25	neoplasms	neoplasm	NNS
cord-022561-rv5j1201	2146	26	,	,	,
cord-022561-rv5j1201	2146	27	and	and	CC
cord-022561-rv5j1201	2146	28	histiocytic	histiocytic	JJ
cord-022561-rv5j1201	2146	29	sarcomas	sarcoma	NNS
cord-022561-rv5j1201	2146	30	,	,	,
cord-022561-rv5j1201	2146	31	can	can	MD
cord-022561-rv5j1201	2146	32	form	form	VB
cord-022561-rv5j1201	2146	33	nodules	nodule	NNS
cord-022561-rv5j1201	2146	34	or	or	CC
cord-022561-rv5j1201	2146	35	diffuse	diffuse	VB
cord-022561-rv5j1201	2146	36	splenic	splenic	JJ
cord-022561-rv5j1201	2146	37	enlargement	enlargement	NN
cord-022561-rv5j1201	2146	38	(	(	-LRB-
cord-022561-rv5j1201	2146	39	or	or	CC
cord-022561-rv5j1201	2146	40	both	both	DT
cord-022561-rv5j1201	2146	41	)	)	-RRB-
cord-022561-rv5j1201	2146	42	.	.	.
cord-022561-rv5j1201	2147	1	Metastatic	Metastatic	NNP
cord-022561-rv5j1201	2147	2	Neoplasms	Neoplasms	NNP
cord-022561-rv5j1201	2147	3	.	.	.
cord-022561-rv5j1201	2148	1	Neoplasms	neoplasm	NNS
cord-022561-rv5j1201	2148	2	that	that	WDT
cord-022561-rv5j1201	2148	3	metastasize	metastasize	VBP
cord-022561-rv5j1201	2148	4	to	to	IN
cord-022561-rv5j1201	2148	5	the	the	DT
cord-022561-rv5j1201	2148	6	spleen	spleen	NN
cord-022561-rv5j1201	2148	7	usually	usually	RB
cord-022561-rv5j1201	2148	8	result	result	VBP
cord-022561-rv5j1201	2148	9	in	in	IN
cord-022561-rv5j1201	2148	10	enlarged	enlarged	JJ
cord-022561-rv5j1201	2148	11	nodular	nodular	JJ
cord-022561-rv5j1201	2148	12	spleens	spleen	NNS
cord-022561-rv5j1201	2148	13	(	(	-LRB-
cord-022561-rv5j1201	2148	14	Fig	Fig	NNP
cord-022561-rv5j1201	2148	15	.	.	.
cord-022561-rv5j1201	2148	16	13	13	CD
cord-022561-rv5j1201	2148	17	-	-	SYM
cord-022561-rv5j1201	2148	18	67	67	CD
cord-022561-rv5j1201	2148	19	)	)	-RRB-
cord-022561-rv5j1201	2148	20	and	and	CC
cord-022561-rv5j1201	2148	21	include	include	VBP
cord-022561-rv5j1201	2148	22	any	any	DT
cord-022561-rv5j1201	2148	23	number	number	NN
cord-022561-rv5j1201	2148	24	of	of	IN
cord-022561-rv5j1201	2148	25	sarcomas	sarcoma	NNS
cord-022561-rv5j1201	2148	26	,	,	,
cord-022561-rv5j1201	2148	27	carcinomas	carcinoma	NNS
cord-022561-rv5j1201	2148	28	,	,	,
cord-022561-rv5j1201	2148	29	or	or	CC
cord-022561-rv5j1201	2148	30	malignant	malignant	JJ
cord-022561-rv5j1201	2148	31	round	round	JJ
cord-022561-rv5j1201	2148	32	cell	cell	NN
cord-022561-rv5j1201	2148	33	tumors	tumor	NNS
cord-022561-rv5j1201	2148	34	.	.	.
cord-022561-rv5j1201	2149	1	Metastatic	metastatic	JJ
cord-022561-rv5j1201	2149	2	sarcomas	sarcoma	NNS
cord-022561-rv5j1201	2149	3	can	can	MD
cord-022561-rv5j1201	2149	4	include	include	VB
cord-022561-rv5j1201	2149	5	fibrosarcomas	fibrosarcomas	NNP
cord-022561-rv5j1201	2149	6	,	,	,
cord-022561-rv5j1201	2149	7	leiomyosarcomas	leiomyosarcomas	NNP
cord-022561-rv5j1201	2149	8	,	,	,
cord-022561-rv5j1201	2149	9	chondrosarcomas	chondrosarcomas	NNP
cord-022561-rv5j1201	2149	10	,	,	,
cord-022561-rv5j1201	2149	11	and	and	CC
cord-022561-rv5j1201	2149	12	osteosarcomas	osteosarcomas	NN
cord-022561-rv5j1201	2149	13	.	.	.
cord-022561-rv5j1201	2150	1	Mammary	mammary	JJ
cord-022561-rv5j1201	2150	2	,	,	,
cord-022561-rv5j1201	2150	3	prostatic	prostatic	JJ
cord-022561-rv5j1201	2150	4	,	,	,
cord-022561-rv5j1201	2150	5	pulmonary	pulmonary	JJ
cord-022561-rv5j1201	2150	6	,	,	,
cord-022561-rv5j1201	2150	7	anal	anal	JJ
cord-022561-rv5j1201	2150	8	sac	sac	NN
cord-022561-rv5j1201	2150	9	gland	gland	NN
cord-022561-rv5j1201	2150	10	and	and	CC
cord-022561-rv5j1201	2150	11	neuroendocrine	neuroendocrine	JJ
cord-022561-rv5j1201	2150	12	carcinomas	carcinoma	NNS
cord-022561-rv5j1201	2150	13	may	may	MD
cord-022561-rv5j1201	2150	14	metastasize	metastasize	VB
cord-022561-rv5j1201	2150	15	widely	widely	RB
cord-022561-rv5j1201	2150	16	to	to	IN
cord-022561-rv5j1201	2150	17	abdominal	abdominal	JJ
cord-022561-rv5j1201	2150	18	viscera	viscera	NNS
cord-022561-rv5j1201	2150	19	,	,	,
cord-022561-rv5j1201	2150	20	including	include	VBG
cord-022561-rv5j1201	2150	21	the	the	DT
cord-022561-rv5j1201	2150	22	spleen	spleen	NN
cord-022561-rv5j1201	2150	23	.	.	.
cord-022561-rv5j1201	2151	1	Granulomas	Granulomas	NNP
cord-022561-rv5j1201	2151	2	and	and	CC
cord-022561-rv5j1201	2151	3	Abscesses	Abscesses	NNPS
cord-022561-rv5j1201	2151	4	.	.	.
cord-022561-rv5j1201	2152	1	Microorganisms	microorganism	NNS
cord-022561-rv5j1201	2152	2	that	that	WDT
cord-022561-rv5j1201	2152	3	cause	cause	VBP
cord-022561-rv5j1201	2152	4	diffuse	diffuse	JJ
cord-022561-rv5j1201	2153	1	granulomatous	granulomatous	JJ
cord-022561-rv5j1201	2153	2	splenitis	splenitis	NNP
cord-022561-rv5j1201	2153	3	and	and	CC
cord-022561-rv5j1201	2153	4	uniform	uniform	JJ
cord-022561-rv5j1201	2153	5	splenomegaly	splenomegaly	NN
cord-022561-rv5j1201	2153	6	may	may	MD
cord-022561-rv5j1201	2153	7	also	also	RB
cord-022561-rv5j1201	2153	8	cause	cause	VB
cord-022561-rv5j1201	2153	9	focal	focal	JJ
cord-022561-rv5j1201	2153	10	to	to	IN
cord-022561-rv5j1201	2153	11	multifocal	multifocal	JJ
cord-022561-rv5j1201	2153	12	nodular	nodular	JJ
cord-022561-rv5j1201	2153	13	lesions	lesion	NNS
cord-022561-rv5j1201	2153	14	(	(	-LRB-
cord-022561-rv5j1201	2153	15	e.g.	e.g.	RB
cord-022561-rv5j1201	2153	16	,	,	,
cord-022561-rv5j1201	2153	17	Mycobacterium	Mycobacterium	NNP
cord-022561-rv5j1201	2153	18	spp	spp	NNS
cord-022561-rv5j1201	2153	19	.	.	.
cord-022561-rv5j1201	2154	1	,	,	,
cord-022561-rv5j1201	2154	2	fungal	fungal	JJ
cord-022561-rv5j1201	2154	3	organisms	organism	NNS
cord-022561-rv5j1201	2154	4	)	)	-RRB-
cord-022561-rv5j1201	2155	1	(	(	-LRB-
cord-022561-rv5j1201	2155	2	see	see	VB
cord-022561-rv5j1201	2155	3	Diffuse	Diffuse	NNP
cord-022561-rv5j1201	2155	4	Granulomatous	granulomatous	JJ
cord-022561-rv5j1201	2155	5	Diseases	disease	NNS
cord-022561-rv5j1201	2155	6	of	of	IN
cord-022561-rv5j1201	2155	7	the	the	DT
cord-022561-rv5j1201	2155	8	Spleen	spleen	NN
cord-022561-rv5j1201	2155	9	and	and	CC
cord-022561-rv5j1201	2155	10	also	also	RB
cord-022561-rv5j1201	2155	11	Enlarged	enlarged	JJ
cord-022561-rv5j1201	2155	12	Lymph	lymph	NN
cord-022561-rv5j1201	2155	13	Nodes	node	NNS
cord-022561-rv5j1201	2155	14	)	)	-RRB-
cord-022561-rv5j1201	2155	15	.	.	.
cord-022561-rv5j1201	2156	1	Although	although	IN
cord-022561-rv5j1201	2156	2	there	there	EX
cord-022561-rv5j1201	2156	3	are	be	VBP
cord-022561-rv5j1201	2156	4	a	a	DT
cord-022561-rv5j1201	2156	5	large	large	JJ
cord-022561-rv5j1201	2156	6	number	number	NN
cord-022561-rv5j1201	2156	7	of	of	IN
cord-022561-rv5j1201	2156	8	abscesses	abscess	NNS
cord-022561-rv5j1201	2156	9	bulge	bulge	VBP
cord-022561-rv5j1201	2156	10	from	from	IN
cord-022561-rv5j1201	2156	11	the	the	DT
cord-022561-rv5j1201	2156	12	capsule	capsule	NN
cord-022561-rv5j1201	2156	13	and	and	CC
cord-022561-rv5j1201	2156	14	cut	cut	NN
cord-022561-rv5j1201	2156	15	surfaces	surface	NNS
cord-022561-rv5j1201	2156	16	,	,	,
cord-022561-rv5j1201	2156	17	and	and	CC
cord-022561-rv5j1201	2156	18	the	the	DT
cord-022561-rv5j1201	2156	19	exudate	exudate	NN
cord-022561-rv5j1201	2156	20	can	can	MD
cord-022561-rv5j1201	2156	21	vary	vary	VB
cord-022561-rv5j1201	2156	22	in	in	IN
cord-022561-rv5j1201	2156	23	amount	amount	NN
cord-022561-rv5j1201	2156	24	,	,	,
cord-022561-rv5j1201	2156	25	texture	texture	NN
cord-022561-rv5j1201	2156	26	,	,	,
cord-022561-rv5j1201	2156	27	and	and	CC
cord-022561-rv5j1201	2156	28	color	color	NN
cord-022561-rv5j1201	2156	29	depending	depend	VBG
cord-022561-rv5j1201	2156	30	on	on	IN
cord-022561-rv5j1201	2156	31	the	the	DT
cord-022561-rv5j1201	2156	32	inciting	incite	VBG
cord-022561-rv5j1201	2156	33	organism	organism	NN
cord-022561-rv5j1201	2156	34	and	and	CC
cord-022561-rv5j1201	2156	35	the	the	DT
cord-022561-rv5j1201	2156	36	age	age	NN
cord-022561-rv5j1201	2156	37	of	of	IN
cord-022561-rv5j1201	2156	38	the	the	DT
cord-022561-rv5j1201	2156	39	lesion	lesion	NN
cord-022561-rv5j1201	2156	40	.	.	.
cord-022561-rv5j1201	2157	1	The	the	DT
cord-022561-rv5j1201	2157	2	most	most	RBS
cord-022561-rv5j1201	2157	3	common	common	JJ
cord-022561-rv5j1201	2157	4	diseases	disease	NNS
cord-022561-rv5j1201	2157	5	or	or	CC
cord-022561-rv5j1201	2157	6	conditions	condition	NNS
cord-022561-rv5j1201	2157	7	that	that	WDT
cord-022561-rv5j1201	2157	8	have	have	VBP
cord-022561-rv5j1201	2157	9	small	small	JJ
cord-022561-rv5j1201	2157	10	spleens	spleen	NNS
cord-022561-rv5j1201	2157	11	are	be	VBP
cord-022561-rv5j1201	2157	12	(	(	-LRB-
cord-022561-rv5j1201	2157	13	1	1	CD
cord-022561-rv5j1201	2157	14	)	)	-RRB-
cord-022561-rv5j1201	2157	15	developmental	developmental	JJ
cord-022561-rv5j1201	2157	16	anomalies	anomaly	NNS
cord-022561-rv5j1201	2157	17	,	,	,
cord-022561-rv5j1201	2157	18	(	(	-LRB-
cord-022561-rv5j1201	2157	19	2	2	LS
cord-022561-rv5j1201	2157	20	)	)	-RRB-
cord-022561-rv5j1201	2157	21	aging	age	VBG
cord-022561-rv5j1201	2157	22	changes	change	NNS
cord-022561-rv5j1201	2157	23	,	,	,
cord-022561-rv5j1201	2157	24	(	(	-LRB-
cord-022561-rv5j1201	2157	25	3	3	LS
cord-022561-rv5j1201	2157	26	)	)	-RRB-
cord-022561-rv5j1201	2157	27	wasting	waste	VBG
cord-022561-rv5j1201	2157	28	and/or	and/or	CC
cord-022561-rv5j1201	2157	29	cachectic	cachectic	JJ
cord-022561-rv5j1201	2157	30	diseases	disease	NNS
cord-022561-rv5j1201	2157	31	,	,	,
cord-022561-rv5j1201	2157	32	and	and	CC
cord-022561-rv5j1201	2157	33	(	(	-LRB-
cord-022561-rv5j1201	2157	34	4	4	LS
cord-022561-rv5j1201	2157	35	)	)	-RRB-
cord-022561-rv5j1201	2157	36	splenic	splenic	JJ
cord-022561-rv5j1201	2157	37	contraction	contraction	NN
cord-022561-rv5j1201	2157	38	.	.	.
cord-022561-rv5j1201	2158	1	Splenic	Splenic	NNP
cord-022561-rv5j1201	2158	2	Hypoplasia	Hypoplasia	NNP
cord-022561-rv5j1201	2158	3	.	.	.
cord-022561-rv5j1201	2159	1	Primary	primary	JJ
cord-022561-rv5j1201	2159	2	immunodeficiency	immunodeficiency	NN
cord-022561-rv5j1201	2159	3	diseases	disease	NNS
cord-022561-rv5j1201	2159	4	can	can	MD
cord-022561-rv5j1201	2159	5	result	result	VB
cord-022561-rv5j1201	2159	6	in	in	IN
cord-022561-rv5j1201	2159	7	splenic	splenic	JJ
cord-022561-rv5j1201	2159	8	hypoplasia	hypoplasia	NN
cord-022561-rv5j1201	2159	9	,	,	,
cord-022561-rv5j1201	2159	10	as	as	RB
cord-022561-rv5j1201	2159	11	well	well	RB
cord-022561-rv5j1201	2159	12	as	as	IN
cord-022561-rv5j1201	2159	13	small	small	JJ
cord-022561-rv5j1201	2159	14	thymuses	thymus	NNS
cord-022561-rv5j1201	2159	15	and	and	CC
cord-022561-rv5j1201	2159	16	lymph	lymph	NN
cord-022561-rv5j1201	2159	17	nodes	node	NNS
cord-022561-rv5j1201	2159	18	(	(	-LRB-
cord-022561-rv5j1201	2159	19	which	which	WDT
cord-022561-rv5j1201	2159	20	may	may	MD
cord-022561-rv5j1201	2159	21	be	be	VB
cord-022561-rv5j1201	2159	22	so	so	RB
cord-022561-rv5j1201	2159	23	small	small	JJ
cord-022561-rv5j1201	2159	24	as	as	IN
cord-022561-rv5j1201	2159	25	to	to	TO
cord-022561-rv5j1201	2159	26	be	be	VB
cord-022561-rv5j1201	2159	27	grossly	grossly	RB
cord-022561-rv5j1201	2159	28	undetectable	undetectable	JJ
cord-022561-rv5j1201	2159	29	in	in	IN
cord-022561-rv5j1201	2159	30	some	some	DT
cord-022561-rv5j1201	2159	31	diseases	disease	NNS
cord-022561-rv5j1201	2159	32	)	)	-RRB-
cord-022561-rv5j1201	2159	33	.	.	.
cord-022561-rv5j1201	2160	1	These	these	DT
cord-022561-rv5j1201	2160	2	diseases	disease	NNS
cord-022561-rv5j1201	2160	3	affect	affect	VBP
cord-022561-rv5j1201	2160	4	young	young	JJ
cord-022561-rv5j1201	2160	5	animals	animal	NNS
cord-022561-rv5j1201	2160	6	and	and	CC
cord-022561-rv5j1201	2160	7	involve	involve	VBP
cord-022561-rv5j1201	2160	8	defects	defect	NNS
cord-022561-rv5j1201	2160	9	in	in	IN
cord-022561-rv5j1201	2160	10	T	T	NNP
cord-022561-rv5j1201	2160	11	and/or	and/or	CC
cord-022561-rv5j1201	2160	12	B	b	NN
cord-022561-rv5j1201	2160	13	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	2161	1	(	(	-LRB-
cord-022561-rv5j1201	2161	2	Fig	Fig	NNP
cord-022561-rv5j1201	2161	3	.	.	.
cord-022561-rv5j1201	2161	4	13	13	CD
cord-022561-rv5j1201	2161	5	-	-	SYM
cord-022561-rv5j1201	2161	6	70	70	CD
cord-022561-rv5j1201	2161	7	)	)	-RRB-
cord-022561-rv5j1201	2161	8	.	.	.
cord-022561-rv5j1201	2162	1	Spleens	spleen	NNS
cord-022561-rv5j1201	2162	2	are	be	VBP
cord-022561-rv5j1201	2162	3	exceptionally	exceptionally	RB
cord-022561-rv5j1201	2162	4	small	small	JJ
cord-022561-rv5j1201	2162	5	,	,	,
cord-022561-rv5j1201	2162	6	firm	firm	JJ
cord-022561-rv5j1201	2162	7	,	,	,
cord-022561-rv5j1201	2162	8	and	and	CC
cord-022561-rv5j1201	2162	9	pale	pale	JJ
cord-022561-rv5j1201	2162	10	red	red	JJ
cord-022561-rv5j1201	2162	11	and	and	CC
cord-022561-rv5j1201	2162	12	lack	lack	JJ
cord-022561-rv5j1201	2162	13	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	2162	14	follicles	follicle	NNS
cord-022561-rv5j1201	2162	15	and	and	CC
cord-022561-rv5j1201	2162	16	PALS	pals	NN
cord-022561-rv5j1201	2162	17	.	.	.
cord-022561-rv5j1201	2163	1	These	these	DT
cord-022561-rv5j1201	2163	2	diseases	disease	NNS
cord-022561-rv5j1201	2163	3	and	and	CC
cord-022561-rv5j1201	2163	4	their	-PRON-	PRP$
cord-022561-rv5j1201	2163	5	pathologic	pathologic	JJ
cord-022561-rv5j1201	2163	6	findings	finding	NNS
cord-022561-rv5j1201	2163	7	are	be	VBP
cord-022561-rv5j1201	2163	8	discussed	discuss	VBN
cord-022561-rv5j1201	2163	9	in	in	IN
cord-022561-rv5j1201	2163	10	Chapter	chapter	NN
cord-022561-rv5j1201	2163	11	5	5	CD
cord-022561-rv5j1201	2163	12	and	and	CC
cord-022561-rv5j1201	2163	13	in	in	IN
cord-022561-rv5j1201	2163	14	the	the	DT
cord-022561-rv5j1201	2163	15	sections	section	NNS
cord-022561-rv5j1201	2163	16	on	on	IN
cord-022561-rv5j1201	2163	17	Disorders	disorder	NNS
cord-022561-rv5j1201	2163	18	of	of	IN
cord-022561-rv5j1201	2163	19	Horses	horse	NNS
cord-022561-rv5j1201	2163	20	and	and	CC
cord-022561-rv5j1201	2163	21	Disorders	disorder	NNS
cord-022561-rv5j1201	2163	22	of	of	IN
cord-022561-rv5j1201	2163	23	Dogs	dog	NNS
cord-022561-rv5j1201	2163	24	.	.	.
cord-022561-rv5j1201	2164	1	Congenital	congenital	JJ
cord-022561-rv5j1201	2164	2	Accessory	accessory	JJ
cord-022561-rv5j1201	2164	3	Spleens	spleen	NNS
cord-022561-rv5j1201	2164	4	.	.	.
cord-022561-rv5j1201	2165	1	Accessory	accessory	JJ
cord-022561-rv5j1201	2165	2	spleens	spleen	NNS
cord-022561-rv5j1201	2165	3	can	can	MD
cord-022561-rv5j1201	2165	4	be	be	VB
cord-022561-rv5j1201	2165	5	either	either	CC
cord-022561-rv5j1201	2165	6	congenital	congenital	JJ
cord-022561-rv5j1201	2165	7	or	or	CC
cord-022561-rv5j1201	2165	8	acquired	acquire	VBN
cord-022561-rv5j1201	2165	9	(	(	-LRB-
cord-022561-rv5j1201	2165	10	see	see	VB
cord-022561-rv5j1201	2165	11	Splenic	Splenic	NNP
cord-022561-rv5j1201	2165	12	Rupture	Rupture	NNP
cord-022561-rv5j1201	2165	13	)	)	-RRB-
cord-022561-rv5j1201	2165	14	.	.	.
cord-022561-rv5j1201	2166	1	Congenital	congenital	JJ
cord-022561-rv5j1201	2166	2	accessory	accessory	NN
cord-022561-rv5j1201	2166	3	spleens	spleen	NNS
cord-022561-rv5j1201	2166	4	are	be	VBP
cord-022561-rv5j1201	2166	5	termed	term	VBN
cord-022561-rv5j1201	2166	6	splenic	splenic	JJ
cord-022561-rv5j1201	2166	7	choristomas	choristoma	NNS
cord-022561-rv5j1201	2166	8	,	,	,
cord-022561-rv5j1201	2166	9	which	which	WDT
cord-022561-rv5j1201	2166	10	are	be	VBP
cord-022561-rv5j1201	2166	11	nodules	nodule	NNS
cord-022561-rv5j1201	2166	12	of	of	IN
cord-022561-rv5j1201	2166	13	normal	normal	JJ
cord-022561-rv5j1201	2166	14	splenic	splenic	JJ
cord-022561-rv5j1201	2166	15	parenchyma	parenchyma	NN
cord-022561-rv5j1201	2166	16	in	in	IN
cord-022561-rv5j1201	2166	17	abnormal	abnormal	JJ
cord-022561-rv5j1201	2166	18	locations	location	NNS
cord-022561-rv5j1201	2166	19	.	.	.
cord-022561-rv5j1201	2167	1	These	these	DT
cord-022561-rv5j1201	2167	2	are	be	VBP
cord-022561-rv5j1201	2167	3	usually	usually	RB
cord-022561-rv5j1201	2167	4	small	small	JJ
cord-022561-rv5j1201	2167	5	diseases	disease	NNS
cord-022561-rv5j1201	2167	6	and	and	CC
cord-022561-rv5j1201	2167	7	conditions	condition	NNS
cord-022561-rv5j1201	2167	8	commonly	commonly	RB
cord-022561-rv5j1201	2167	9	caused	cause	VBN
cord-022561-rv5j1201	2167	10	by	by	IN
cord-022561-rv5j1201	2167	11	bacteremia	bacteremia	NN
cord-022561-rv5j1201	2167	12	(	(	-LRB-
cord-022561-rv5j1201	2167	13	e.g.	e.g.	RB
cord-022561-rv5j1201	2167	14	,	,	,
cord-022561-rv5j1201	2167	15	navel	navel	NN
cord-022561-rv5j1201	2167	16	ill	ill	JJ
cord-022561-rv5j1201	2167	17	,	,	,
cord-022561-rv5j1201	2167	18	joint	joint	JJ
cord-022561-rv5j1201	2167	19	ill	ill	JJ
cord-022561-rv5j1201	2167	20	,	,	,
cord-022561-rv5j1201	2167	21	chronic	chronic	JJ
cord-022561-rv5j1201	2167	22	respiratory	respiratory	JJ
cord-022561-rv5j1201	2167	23	infections	infection	NNS
cord-022561-rv5j1201	2167	24	,	,	,
cord-022561-rv5j1201	2167	25	bacterial	bacterial	JJ
cord-022561-rv5j1201	2167	26	endocarditis	endocarditis	NN
cord-022561-rv5j1201	2167	27	,	,	,
cord-022561-rv5j1201	2167	28	chronic	chronic	JJ
cord-022561-rv5j1201	2167	29	skin	skin	NN
cord-022561-rv5j1201	2167	30	diseases	disease	NNS
cord-022561-rv5j1201	2167	31	,	,	,
cord-022561-rv5j1201	2167	32	castration	castration	NN
cord-022561-rv5j1201	2167	33	,	,	,
cord-022561-rv5j1201	2167	34	tail	tail	NN
cord-022561-rv5j1201	2167	35	docking	docking	NN
cord-022561-rv5j1201	2167	36	,	,	,
cord-022561-rv5j1201	2167	37	and	and	CC
cord-022561-rv5j1201	2167	38	ear	ear	NN
cord-022561-rv5j1201	2167	39	trimming	trim	VBG
cord-022561-rv5j1201	2167	40	and/	and/	CD
cord-022561-rv5j1201	2167	41	or	or	CC
cord-022561-rv5j1201	2167	42	notching	notching	NN
cord-022561-rv5j1201	2167	43	)	)	-RRB-
cord-022561-rv5j1201	2167	44	,	,	,
cord-022561-rv5j1201	2167	45	these	these	DT
cord-022561-rv5j1201	2167	46	rarely	rarely	RB
cord-022561-rv5j1201	2167	47	result	result	VBP
cord-022561-rv5j1201	2167	48	in	in	IN
cord-022561-rv5j1201	2167	49	visible	visible	JJ
cord-022561-rv5j1201	2167	50	splenic	splenic	JJ
cord-022561-rv5j1201	2167	51	abscesses	abscess	NNS
cord-022561-rv5j1201	2167	52	.	.	.
cord-022561-rv5j1201	2168	1	Pyogranulomas	pyogranulomas	NN
cord-022561-rv5j1201	2168	2	and	and	CC
cord-022561-rv5j1201	2168	3	abscesses	abscess	NNS
cord-022561-rv5j1201	2168	4	in	in	IN
cord-022561-rv5j1201	2168	5	the	the	DT
cord-022561-rv5j1201	2168	6	spleen	spleen	NN
cord-022561-rv5j1201	2168	7	(	(	-LRB-
cord-022561-rv5j1201	2168	8	multifocal	multifocal	JJ
cord-022561-rv5j1201	2168	9	chronic	chronic	JJ
cord-022561-rv5j1201	2168	10	suppurative	suppurative	JJ
cord-022561-rv5j1201	2168	11	splenitis	splenitis	NNP
cord-022561-rv5j1201	2168	12	)	)	-RRB-
cord-022561-rv5j1201	2168	13	that	that	WDT
cord-022561-rv5j1201	2168	14	do	do	VBP
cord-022561-rv5j1201	2168	15	develop	develop	VB
cord-022561-rv5j1201	2168	16	after	after	IN
cord-022561-rv5j1201	2168	17	septicemia	septicemia	NN
cord-022561-rv5j1201	2169	1	and/or	and/or	CC
cord-022561-rv5j1201	2170	1	bacteremia	bacteremia	NN
cord-022561-rv5j1201	2170	2	are	be	VBP
cord-022561-rv5j1201	2170	3	usually	usually	RB
cord-022561-rv5j1201	2170	4	caused	cause	VBN
cord-022561-rv5j1201	2170	5	by	by	IN
cord-022561-rv5j1201	2170	6	pyogenic	pyogenic	JJ
cord-022561-rv5j1201	2170	7	bacteria	bacteria	NNS
cord-022561-rv5j1201	2170	8	such	such	JJ
cord-022561-rv5j1201	2170	9	as	as	IN
cord-022561-rv5j1201	2170	10	Streptococcus	Streptococcus	NNP
cord-022561-rv5j1201	2170	11	spp	spp	NNS
cord-022561-rv5j1201	2170	12	.	.	.
cord-022561-rv5j1201	2171	1	,	,	,
cord-022561-rv5j1201	2171	2	Rhodococcus	Rhodococcus	NNP
cord-022561-rv5j1201	2171	3	equi	equi	NN
cord-022561-rv5j1201	2171	4	(	(	-LRB-
cord-022561-rv5j1201	2171	5	Fig	Fig	NNP
cord-022561-rv5j1201	2171	6	.	.	.
cord-022561-rv5j1201	2171	7	13	13	CD
cord-022561-rv5j1201	2171	8	-	-	SYM
cord-022561-rv5j1201	2171	9	68	68	CD
cord-022561-rv5j1201	2171	10	)	)	-RRB-
cord-022561-rv5j1201	2171	11	,	,	,
cord-022561-rv5j1201	2171	12	Trueperella	Trueperella	NNP
cord-022561-rv5j1201	2171	13	pyogenes	pyogene	NNS
cord-022561-rv5j1201	2171	14	(	(	-LRB-
cord-022561-rv5j1201	2171	15	Fig	Fig	NNP
cord-022561-rv5j1201	2171	16	.	.	.
cord-022561-rv5j1201	2171	17	13	13	CD
cord-022561-rv5j1201	2171	18	-	-	SYM
cord-022561-rv5j1201	2171	19	69	69	CD
cord-022561-rv5j1201	2171	20	)	)	-RRB-
cord-022561-rv5j1201	2171	21	,	,	,
cord-022561-rv5j1201	2171	22	and	and	CC
cord-022561-rv5j1201	2171	23	Corynebacterium	Corynebacterium	NNP
cord-022561-rv5j1201	2171	24	pseudotuberculosis	pseudotuberculosis	NN
cord-022561-rv5j1201	2171	25	.	.	.
cord-022561-rv5j1201	2172	1	Cats	cat	NNS
cord-022561-rv5j1201	2172	2	with	with	IN
cord-022561-rv5j1201	2172	3	the	the	DT
cord-022561-rv5j1201	2172	4	wet	wet	JJ
cord-022561-rv5j1201	2172	5	or	or	CC
cord-022561-rv5j1201	2172	6	dry	dry	JJ
cord-022561-rv5j1201	2172	7	form	form	NN
cord-022561-rv5j1201	2172	8	of	of	IN
cord-022561-rv5j1201	2172	9	feline	feline	JJ
cord-022561-rv5j1201	2172	10	infectious	infectious	JJ
cord-022561-rv5j1201	2172	11	peritonitis	peritonitis	NN
cord-022561-rv5j1201	2172	12	virus	virus	NN
cord-022561-rv5j1201	2172	13	may	may	MD
cord-022561-rv5j1201	2172	14	have	have	VB
cord-022561-rv5j1201	2172	15	nodular	nodular	JJ
cord-022561-rv5j1201	2172	16	pyogranulomatous	pyogranulomatous	JJ
cord-022561-rv5j1201	2172	17	and	and	CC
cord-022561-rv5j1201	2172	18	lymphoplasmacytic	lymphoplasmacytic	JJ
cord-022561-rv5j1201	2172	19	inflammatory	inflammatory	JJ
cord-022561-rv5j1201	2172	20	foci	foci	NN
cord-022561-rv5j1201	2172	21	throughout	throughout	IN
cord-022561-rv5j1201	2172	22	the	the	DT
cord-022561-rv5j1201	2172	23	spleen	spleen	NN
cord-022561-rv5j1201	2172	24	.	.	.
cord-022561-rv5j1201	2173	1	Splenic	Splenic	NNP
cord-022561-rv5j1201	2173	2	abscesses	abscess	NNS
cord-022561-rv5j1201	2173	3	due	due	JJ
cord-022561-rv5j1201	2173	4	to	to	IN
cord-022561-rv5j1201	2173	5	direct	direct	JJ
cord-022561-rv5j1201	2173	6	penetration	penetration	NN
cord-022561-rv5j1201	2173	7	by	by	IN
cord-022561-rv5j1201	2173	8	a	a	DT
cord-022561-rv5j1201	2173	9	migrating	migrate	VBG
cord-022561-rv5j1201	2173	10	foreign	foreign	JJ
cord-022561-rv5j1201	2173	11	body	body	NN
cord-022561-rv5j1201	2173	12	are	be	VBP
cord-022561-rv5j1201	2173	13	reported	report	VBN
cord-022561-rv5j1201	2173	14	in	in	IN
cord-022561-rv5j1201	2173	15	cattle	cattle	NNS
cord-022561-rv5j1201	2173	16	(	(	-LRB-
cord-022561-rv5j1201	2173	17	from	from	IN
cord-022561-rv5j1201	2173	18	the	the	DT
cord-022561-rv5j1201	2173	19	reticulum	reticulum	NN
cord-022561-rv5j1201	2173	20	)	)	-RRB-
cord-022561-rv5j1201	2173	21	and	and	CC
cord-022561-rv5j1201	2173	22	less	less	RBR
cord-022561-rv5j1201	2173	23	commonly	commonly	RB
cord-022561-rv5j1201	2173	24	in	in	IN
cord-022561-rv5j1201	2173	25	the	the	DT
cord-022561-rv5j1201	2173	26	horse	horse	NN
cord-022561-rv5j1201	2173	27	(	(	-LRB-
cord-022561-rv5j1201	2173	28	from	from	IN
cord-022561-rv5j1201	2173	29	the	the	DT
cord-022561-rv5j1201	2173	30	stomach	stomach	NN
cord-022561-rv5j1201	2173	31	)	)	-RRB-
cord-022561-rv5j1201	2173	32	.	.	.
cord-022561-rv5j1201	2174	1	Perforating	perforate	VBG
cord-022561-rv5j1201	2174	2	gastric	gastric	JJ
cord-022561-rv5j1201	2174	3	ulcers	ulcer	NNS
cord-022561-rv5j1201	2174	4	in	in	IN
cord-022561-rv5j1201	2174	5	horses	horse	NNS
cord-022561-rv5j1201	2174	6	due	due	JJ
cord-022561-rv5j1201	2174	7	to	to	IN
cord-022561-rv5j1201	2174	8	Gasterophilus	Gasterophilus	NNP
cord-022561-rv5j1201	2174	9	and	and	CC
cord-022561-rv5j1201	2174	10	Habronema	Habronema	NNP
cord-022561-rv5j1201	2174	11	spp	spp	NNS
cord-022561-rv5j1201	2174	12	.	.	.
cord-022561-rv5j1201	2175	1	have	have	VBP
cord-022561-rv5j1201	2175	2	also	also	RB
cord-022561-rv5j1201	2175	3	reportedly	reportedly	RB
cord-022561-rv5j1201	2175	4	led	lead	VBN
cord-022561-rv5j1201	2175	5	to	to	IN
cord-022561-rv5j1201	2175	6	adjacent	adjacent	JJ
cord-022561-rv5j1201	2175	7	splenic	splenic	JJ
cord-022561-rv5j1201	2175	8	abscesses	abscess	NNS
cord-022561-rv5j1201	2175	9	.	.	.
cord-022561-rv5j1201	2176	1	Granulomas	Granulomas	NNP
cord-022561-rv5j1201	2176	2	and	and	CC
cord-022561-rv5j1201	2176	3	A	a	DT
cord-022561-rv5j1201	2176	4	B	b	NN
cord-022561-rv5j1201	2176	5	and	and	CC
cord-022561-rv5j1201	2176	6	may	may	MD
cord-022561-rv5j1201	2176	7	be	be	VB
cord-022561-rv5j1201	2176	8	located	locate	VBN
cord-022561-rv5j1201	2176	9	in	in	IN
cord-022561-rv5j1201	2176	10	the	the	DT
cord-022561-rv5j1201	2176	11	gastrosplenic	gastrosplenic	NNP
cord-022561-rv5j1201	2176	12	ligament	ligament	NN
cord-022561-rv5j1201	2176	13	,	,	,
cord-022561-rv5j1201	2176	14	liver	liver	NN
cord-022561-rv5j1201	2176	15	,	,	,
cord-022561-rv5j1201	2176	16	or	or	CC
cord-022561-rv5j1201	2176	17	pancreas	pancreas	NN
cord-022561-rv5j1201	2176	18	(	(	-LRB-
cord-022561-rv5j1201	2176	19	see	see	VB
cord-022561-rv5j1201	2176	20	Fig	Fig	NNP
cord-022561-rv5j1201	2176	21	.	.	.
cord-022561-rv5j1201	2177	1	13	13	CD
cord-022561-rv5j1201	2177	2	-	-	SYM
cord-022561-rv5j1201	2177	3	74	74	CD
cord-022561-rv5j1201	2177	4	,	,	,
cord-022561-rv5j1201	2177	5	B	b	NN
cord-022561-rv5j1201	2177	6	)	)	-RRB-
cord-022561-rv5j1201	2177	7	.	.	.
cord-022561-rv5j1201	2178	1	Splenic	Splenic	NNP
cord-022561-rv5j1201	2178	2	Fissures	fissure	NNS
cord-022561-rv5j1201	2178	3	.	.	.
cord-022561-rv5j1201	2179	1	Fissures	fissure	NNS
cord-022561-rv5j1201	2179	2	in	in	IN
cord-022561-rv5j1201	2179	3	the	the	DT
cord-022561-rv5j1201	2179	4	splenic	splenic	JJ
cord-022561-rv5j1201	2179	5	capsule	capsule	NN
cord-022561-rv5j1201	2179	6	are	be	VBP
cord-022561-rv5j1201	2179	7	elongated	elongated	JJ
cord-022561-rv5j1201	2179	8	grooves	groove	NNS
cord-022561-rv5j1201	2179	9	whose	whose	WP$
cord-022561-rv5j1201	2179	10	axes	axis	NNS
cord-022561-rv5j1201	2179	11	run	run	VBP
cord-022561-rv5j1201	2179	12	parallel	parallel	RB
cord-022561-rv5j1201	2179	13	to	to	IN
cord-022561-rv5j1201	2179	14	the	the	DT
cord-022561-rv5j1201	2179	15	borders	border	NNS
cord-022561-rv5j1201	2179	16	of	of	IN
cord-022561-rv5j1201	2179	17	the	the	DT
cord-022561-rv5j1201	2179	18	spleen	spleen	NN
cord-022561-rv5j1201	2179	19	.	.	.
cord-022561-rv5j1201	2180	1	This	this	DT
cord-022561-rv5j1201	2180	2	developmental	developmental	JJ
cord-022561-rv5j1201	2180	3	defect	defect	NN
cord-022561-rv5j1201	2180	4	is	be	VBZ
cord-022561-rv5j1201	2180	5	seen	see	VBN
cord-022561-rv5j1201	2180	6	most	most	RBS
cord-022561-rv5j1201	2180	7	commonly	commonly	RB
cord-022561-rv5j1201	2180	8	in	in	IN
cord-022561-rv5j1201	2180	9	horses	horse	NNS
cord-022561-rv5j1201	2180	10	but	but	CC
cord-022561-rv5j1201	2180	11	also	also	RB
cord-022561-rv5j1201	2180	12	occurs	occur	VBZ
cord-022561-rv5j1201	2180	13	in	in	IN
cord-022561-rv5j1201	2180	14	other	other	JJ
cord-022561-rv5j1201	2180	15	domestic	domestic	JJ
cord-022561-rv5j1201	2180	16	animals	animal	NNS
cord-022561-rv5j1201	2180	17	and	and	CC
cord-022561-rv5j1201	2180	18	has	have	VBZ
cord-022561-rv5j1201	2180	19	no	no	DT
cord-022561-rv5j1201	2180	20	pathologic	pathologic	JJ
cord-022561-rv5j1201	2180	21	significance	significance	NN
cord-022561-rv5j1201	2180	22	.	.	.
cord-022561-rv5j1201	2181	1	The	the	DT
cord-022561-rv5j1201	2181	2	surface	surface	NN
cord-022561-rv5j1201	2181	3	of	of	IN
cord-022561-rv5j1201	2181	4	the	the	DT
cord-022561-rv5j1201	2181	5	fissure	fissure	NN
cord-022561-rv5j1201	2181	6	is	be	VBZ
cord-022561-rv5j1201	2181	7	smooth	smooth	JJ
cord-022561-rv5j1201	2181	8	and	and	CC
cord-022561-rv5j1201	2181	9	covered	cover	VBN
cord-022561-rv5j1201	2181	10	by	by	IN
cord-022561-rv5j1201	2181	11	the	the	DT
cord-022561-rv5j1201	2181	12	normal	normal	JJ
cord-022561-rv5j1201	2181	13	splenic	splenic	JJ
cord-022561-rv5j1201	2181	14	capsule	capsule	NN
cord-022561-rv5j1201	2181	15	.	.	.
cord-022561-rv5j1201	2182	1	Aging	age	VBG
cord-022561-rv5j1201	2182	2	Changes	change	NNS
cord-022561-rv5j1201	2182	3	.	.	.
cord-022561-rv5j1201	2183	1	As	as	IN
cord-022561-rv5j1201	2183	2	part	part	NN
cord-022561-rv5j1201	2183	3	of	of	IN
cord-022561-rv5j1201	2183	4	the	the	DT
cord-022561-rv5j1201	2183	5	general	general	JJ
cord-022561-rv5j1201	2183	6	aging	age	VBG
cord-022561-rv5j1201	2183	7	change	change	NN
cord-022561-rv5j1201	2183	8	of	of	IN
cord-022561-rv5j1201	2183	9	cells	cell	NNS
cord-022561-rv5j1201	2183	10	as	as	IN
cord-022561-rv5j1201	2183	11	the	the	DT
cord-022561-rv5j1201	2183	12	body	body	NN
cord-022561-rv5j1201	2183	13	ages	age	NNS
cord-022561-rv5j1201	2183	14	,	,	,
cord-022561-rv5j1201	2183	15	there	there	EX
cord-022561-rv5j1201	2183	16	is	be	VBZ
cord-022561-rv5j1201	2183	17	reduction	reduction	NN
cord-022561-rv5j1201	2183	18	in	in	IN
cord-022561-rv5j1201	2183	19	the	the	DT
cord-022561-rv5j1201	2183	20	number	number	NN
cord-022561-rv5j1201	2183	21	of	of	IN
cord-022561-rv5j1201	2183	22	B	b	NN
cord-022561-rv5j1201	2183	23	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	2183	24	produced	produce	VBN
cord-022561-rv5j1201	2183	25	by	by	IN
cord-022561-rv5j1201	2183	26	the	the	DT
cord-022561-rv5j1201	2183	27	bone	bone	NN
cord-022561-rv5j1201	2183	28	marrow	marrow	NN
cord-022561-rv5j1201	2183	29	and	and	CC
cord-022561-rv5j1201	2183	30	decline	decline	NN
cord-022561-rv5j1201	2183	31	of	of	IN
cord-022561-rv5j1201	2183	32	naïve	naïve	JJ
cord-022561-rv5j1201	2183	33	T	t	NN
cord-022561-rv5j1201	2183	34	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	2183	35	due	due	JJ
cord-022561-rv5j1201	2183	36	to	to	IN
cord-022561-rv5j1201	2183	37	age	age	NN
cord-022561-rv5j1201	2183	38	-	-	HYPH
cord-022561-rv5j1201	2183	39	related	relate	VBN
cord-022561-rv5j1201	2183	40	thymic	thymic	JJ
cord-022561-rv5j1201	2183	41	involution	involution	NN
cord-022561-rv5j1201	2183	42	.	.	.
cord-022561-rv5j1201	2184	1	Consequently	consequently	RB
cord-022561-rv5j1201	2184	2	,	,	,
cord-022561-rv5j1201	2184	3	there	there	EX
cord-022561-rv5j1201	2184	4	is	be	VBZ
cord-022561-rv5j1201	2184	5	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	2184	6	atrophy	atrophy	NN
cord-022561-rv5j1201	2184	7	in	in	IN
cord-022561-rv5j1201	2184	8	secondary	secondary	JJ
cord-022561-rv5j1201	2184	9	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	2184	10	organs	organ	NNS
cord-022561-rv5j1201	2184	11	.	.	.
cord-022561-rv5j1201	2185	1	The	the	DT
cord-022561-rv5j1201	2185	2	spleen	spleen	NN
cord-022561-rv5j1201	2185	3	is	be	VBZ
cord-022561-rv5j1201	2185	4	small	small	JJ
cord-022561-rv5j1201	2185	5	,	,	,
cord-022561-rv5j1201	2185	6	and	and	CC
cord-022561-rv5j1201	2185	7	its	-PRON-	PRP$
cord-022561-rv5j1201	2185	8	capsule	capsule	NN
cord-022561-rv5j1201	2185	9	may	may	MD
cord-022561-rv5j1201	2185	10	be	be	VB
cord-022561-rv5j1201	2185	11	wrinkled	wrinkled	JJ
cord-022561-rv5j1201	2185	12	.	.	.
cord-022561-rv5j1201	2186	1	Microscopically	microscopically	RB
cord-022561-rv5j1201	2186	2	,	,	,
cord-022561-rv5j1201	2186	3	the	the	DT
cord-022561-rv5j1201	2186	4	white	white	JJ
cord-022561-rv5j1201	2186	5	pulp	pulp	NN
cord-022561-rv5j1201	2186	6	is	be	VBZ
cord-022561-rv5j1201	2186	7	atrophied	atrophy	VBN
cord-022561-rv5j1201	2186	8	,	,	,
cord-022561-rv5j1201	2186	9	and	and	CC
cord-022561-rv5j1201	2186	10	splenic	splenic	JJ
cord-022561-rv5j1201	2186	11	follicles	follicle	NNS
cord-022561-rv5j1201	2186	12	,	,	,
cord-022561-rv5j1201	2186	13	if	if	IN
cord-022561-rv5j1201	2186	14	present	present	JJ
cord-022561-rv5j1201	2186	15	,	,	,
cord-022561-rv5j1201	2186	16	lack	lack	VBP
cord-022561-rv5j1201	2186	17	germinal	germinal	JJ
cord-022561-rv5j1201	2186	18	centers	center	NNS
cord-022561-rv5j1201	2186	19	.	.	.
cord-022561-rv5j1201	2187	1	Sinuses	sinus	NNS
cord-022561-rv5j1201	2187	2	may	may	MD
cord-022561-rv5j1201	2187	3	also	also	RB
cord-022561-rv5j1201	2187	4	collapse	collapse	VB
cord-022561-rv5j1201	2187	5	from	from	IN
cord-022561-rv5j1201	2187	6	a	a	DT
cord-022561-rv5j1201	2187	7	reduced	reduce	VBN
cord-022561-rv5j1201	2187	8	amount	amount	NN
cord-022561-rv5j1201	2187	9	of	of	IN
cord-022561-rv5j1201	2187	10	blood	blood	NN
cord-022561-rv5j1201	2187	11	,	,	,
cord-022561-rv5j1201	2187	12	possibly	possibly	RB
cord-022561-rv5j1201	2187	13	because	because	IN
cord-022561-rv5j1201	2187	14	of	of	IN
cord-022561-rv5j1201	2187	15	anemia	anemia	NN
cord-022561-rv5j1201	2187	16	,	,	,
cord-022561-rv5j1201	2187	17	which	which	WDT
cord-022561-rv5j1201	2187	18	makes	make	VBZ
cord-022561-rv5j1201	2187	19	the	the	DT
cord-022561-rv5j1201	2187	20	red	red	JJ
cord-022561-rv5j1201	2187	21	pulp	pulp	NN
cord-022561-rv5j1201	2187	22	appear	appear	VBP
cord-022561-rv5j1201	2187	23	fibrous	fibrous	JJ
cord-022561-rv5j1201	2187	24	.	.	.
cord-022561-rv5j1201	2188	1	Wasting	waste	VBG
cord-022561-rv5j1201	2188	2	/	/	SYM
cord-022561-rv5j1201	2188	3	Cachectic	Cachectic	NNP
cord-022561-rv5j1201	2188	4	Diseases	Diseases	NNPS
cord-022561-rv5j1201	2188	5	.	.	.
cord-022561-rv5j1201	2189	1	Any	any	DT
cord-022561-rv5j1201	2189	2	chronic	chronic	JJ
cord-022561-rv5j1201	2189	3	disease	disease	NN
cord-022561-rv5j1201	2189	4	,	,	,
cord-022561-rv5j1201	2189	5	such	such	JJ
cord-022561-rv5j1201	2189	6	as	as	IN
cord-022561-rv5j1201	2189	7	starvation	starvation	NN
cord-022561-rv5j1201	2189	8	,	,	,
cord-022561-rv5j1201	2189	9	systemic	systemic	JJ
cord-022561-rv5j1201	2189	10	neoplasia	neoplasia	NN
cord-022561-rv5j1201	2189	11	,	,	,
cord-022561-rv5j1201	2189	12	and	and	CC
cord-022561-rv5j1201	2189	13	malabsorption	malabsorption	NN
cord-022561-rv5j1201	2189	14	syndrome	syndrome	NN
cord-022561-rv5j1201	2189	15	,	,	,
cord-022561-rv5j1201	2189	16	may	may	MD
cord-022561-rv5j1201	2189	17	produce	produce	VB
cord-022561-rv5j1201	2189	18	cachexia	cachexia	NN
cord-022561-rv5j1201	2189	19	.	.	.
cord-022561-rv5j1201	2190	1	Starvation	starvation	NN
cord-022561-rv5j1201	2190	2	has	have	VBZ
cord-022561-rv5j1201	2190	3	a	a	DT
cord-022561-rv5j1201	2190	4	marked	marked	JJ
cord-022561-rv5j1201	2190	5	effect	effect	NN
cord-022561-rv5j1201	2190	6	on	on	IN
cord-022561-rv5j1201	2190	7	the	the	DT
cord-022561-rv5j1201	2190	8	thymus	thymus	NN
cord-022561-rv5j1201	2190	9	,	,	,
cord-022561-rv5j1201	2190	10	which	which	WDT
cord-022561-rv5j1201	2190	11	results	result	VBZ
cord-022561-rv5j1201	2190	12	in	in	IN
cord-022561-rv5j1201	2190	13	atrophy	atrophy	NN
cord-022561-rv5j1201	2190	14	of	of	IN
cord-022561-rv5j1201	2190	15	the	the	DT
cord-022561-rv5j1201	2190	16	T	T	NNP
cord-022561-rv5j1201	2190	17	lymphocyte	lymphocyte	NN
cord-022561-rv5j1201	2190	18	areas	area	NNS
cord-022561-rv5j1201	2190	19	in	in	IN
cord-022561-rv5j1201	2190	20	the	the	DT
cord-022561-rv5j1201	2190	21	spleen	spleen	NN
cord-022561-rv5j1201	2190	22	and	and	CC
cord-022561-rv5j1201	2190	23	lymph	lymph	NN
cord-022561-rv5j1201	2190	24	nodes	node	NNS
cord-022561-rv5j1201	2190	25	,	,	,
cord-022561-rv5j1201	2190	26	which	which	WDT
cord-022561-rv5j1201	2190	27	is	be	VBZ
cord-022561-rv5j1201	2190	28	in	in	IN
cord-022561-rv5j1201	2190	29	part	part	NN
cord-022561-rv5j1201	2190	30	mediated	mediate	VBN
cord-022561-rv5j1201	2190	31	by	by	IN
cord-022561-rv5j1201	2190	32	leptin	leptin	NN
cord-022561-rv5j1201	2190	33	.	.	.
cord-022561-rv5j1201	2191	1	B	b	NN
cord-022561-rv5j1201	2191	2	lymphocyte	lymphocyte	NN
cord-022561-rv5j1201	2191	3	development	development	NN
cord-022561-rv5j1201	2191	4	is	be	VBZ
cord-022561-rv5j1201	2191	5	also	also	RB
cord-022561-rv5j1201	2191	6	diminished	diminish	VBN
cord-022561-rv5j1201	2191	7	,	,	,
cord-022561-rv5j1201	2191	8	because	because	IN
cord-022561-rv5j1201	2191	9	B	b	NN
cord-022561-rv5j1201	2191	10	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	2191	11	require	require	VBP
cord-022561-rv5j1201	2191	12	accessory	accessory	JJ
cord-022561-rv5j1201	2191	13	signals	signal	NNS
cord-022561-rv5j1201	2191	14	from	from	IN
cord-022561-rv5j1201	2191	15	helper	helper	NN
cord-022561-rv5j1201	2191	16	T	t	NN
cord-022561-rv5j1201	2191	17	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	2191	18	to	to	TO
cord-022561-rv5j1201	2191	19	undergo	undergo	VB
cord-022561-rv5j1201	2191	20	somatic	somatic	JJ
cord-022561-rv5j1201	2191	21	hypermutation	hypermutation	NN
cord-022561-rv5j1201	2191	22	and	and	CC
cord-022561-rv5j1201	2191	23	immunoglobulin	immunoglobulin	NN
cord-022561-rv5j1201	2191	24	isotype	isotype	NN
cord-022561-rv5j1201	2191	25	switching	switch	VBG
cord-022561-rv5j1201	2191	26	.	.	.
cord-022561-rv5j1201	2192	1	Splenic	Splenic	NNP
cord-022561-rv5j1201	2192	2	Contraction	Contraction	NNP
cord-022561-rv5j1201	2192	3	.	.	.
cord-022561-rv5j1201	2193	1	Contraction	contraction	NN
cord-022561-rv5j1201	2193	2	of	of	IN
cord-022561-rv5j1201	2193	3	the	the	DT
cord-022561-rv5j1201	2193	4	spleen	spleen	NN
cord-022561-rv5j1201	2193	5	is	be	VBZ
cord-022561-rv5j1201	2193	6	a	a	DT
cord-022561-rv5j1201	2193	7	result	result	NN
cord-022561-rv5j1201	2193	8	of	of	IN
cord-022561-rv5j1201	2193	9	contraction	contraction	NN
cord-022561-rv5j1201	2193	10	of	of	IN
cord-022561-rv5j1201	2193	11	the	the	DT
cord-022561-rv5j1201	2193	12	smooth	smooth	JJ
cord-022561-rv5j1201	2193	13	muscle	muscle	NN
cord-022561-rv5j1201	2193	14	in	in	IN
cord-022561-rv5j1201	2193	15	the	the	DT
cord-022561-rv5j1201	2193	16	capsule	capsule	NN
cord-022561-rv5j1201	2193	17	and	and	CC
cord-022561-rv5j1201	2193	18	trabeculae	trabecula	NNS
cord-022561-rv5j1201	2193	19	of	of	IN
cord-022561-rv5j1201	2193	20	storage	storage	NN
cord-022561-rv5j1201	2193	21	spleens	spleen	NNS
cord-022561-rv5j1201	2193	22	.	.	.
cord-022561-rv5j1201	2194	1	It	-PRON-	PRP
cord-022561-rv5j1201	2194	2	can	can	MD
cord-022561-rv5j1201	2194	3	be	be	VB
cord-022561-rv5j1201	2194	4	induced	induce	VBN
cord-022561-rv5j1201	2194	5	by	by	IN
cord-022561-rv5j1201	2194	6	the	the	DT
cord-022561-rv5j1201	2194	7	activation	activation	NN
cord-022561-rv5j1201	2194	8	of	of	IN
cord-022561-rv5j1201	2194	9	the	the	DT
cord-022561-rv5j1201	2194	10	sympathetic	sympathetic	JJ
cord-022561-rv5j1201	2194	11	"	"	``
cord-022561-rv5j1201	2194	12	fight	fight	NN
cord-022561-rv5j1201	2194	13	-	-	HYPH
cord-022561-rv5j1201	2194	14	or	or	CC
cord-022561-rv5j1201	2194	15	-	-	HYPH
cord-022561-rv5j1201	2194	16	flight	flight	NN
cord-022561-rv5j1201	2194	17	"	"	''
cord-022561-rv5j1201	2194	18	response	response	NN
cord-022561-rv5j1201	2194	19	and	and	CC
cord-022561-rv5j1201	2194	20	is	be	VBZ
cord-022561-rv5j1201	2194	21	seen	see	VBN
cord-022561-rv5j1201	2194	22	in	in	IN
cord-022561-rv5j1201	2194	23	patients	patient	NNS
cord-022561-rv5j1201	2194	24	with	with	IN
cord-022561-rv5j1201	2194	25	heart	heart	NN
cord-022561-rv5j1201	2194	26	failure	failure	NN
cord-022561-rv5j1201	2194	27	or	or	CC
cord-022561-rv5j1201	2194	28	shock	shock	NN
cord-022561-rv5j1201	2194	29	(	(	-LRB-
cord-022561-rv5j1201	2194	30	cardiogenic	cardiogenic	UH
cord-022561-rv5j1201	2194	31	,	,	,
cord-022561-rv5j1201	2194	32	hypovolemic	hypovolemic	JJ
cord-022561-rv5j1201	2194	33	,	,	,
cord-022561-rv5j1201	2194	34	and	and	CC
cord-022561-rv5j1201	2194	35	septic	septic	JJ
cord-022561-rv5j1201	2194	36	shock	shock	NN
cord-022561-rv5j1201	2194	37	)	)	-RRB-
cord-022561-rv5j1201	2194	38	and	and	CC
cord-022561-rv5j1201	2194	39	also	also	RB
cord-022561-rv5j1201	2194	40	occurs	occur	VBZ
cord-022561-rv5j1201	2194	41	in	in	IN
cord-022561-rv5j1201	2194	42	acute	acute	JJ
cord-022561-rv5j1201	2194	43	splenic	splenic	JJ
cord-022561-rv5j1201	2194	44	rupture	rupture	NN
cord-022561-rv5j1201	2194	45	that	that	WDT
cord-022561-rv5j1201	2194	46	has	have	VBZ
cord-022561-rv5j1201	2194	47	resulted	result	VBN
cord-022561-rv5j1201	2194	48	in	in	IN
cord-022561-rv5j1201	2194	49	massive	massive	JJ
cord-022561-rv5j1201	2194	50	hemorrhage	hemorrhage	NN
cord-022561-rv5j1201	2194	51	(	(	-LRB-
cord-022561-rv5j1201	2194	52	hemoabdomen	hemoabdomen	NNP
cord-022561-rv5j1201	2194	53	/	/	SYM
cord-022561-rv5j1201	2194	54	hemoperitoneum	hemoperitoneum	NNP
cord-022561-rv5j1201	2194	55	)	)	-RRB-
cord-022561-rv5j1201	2194	56	.	.	.
cord-022561-rv5j1201	2195	1	The	the	DT
cord-022561-rv5j1201	2195	2	contracted	contract	VBN
cord-022561-rv5j1201	2195	3	spleen	spleen	NN
cord-022561-rv5j1201	2195	4	is	be	VBZ
cord-022561-rv5j1201	2195	5	small	small	JJ
cord-022561-rv5j1201	2195	6	,	,	,
cord-022561-rv5j1201	2195	7	its	-PRON-	PRP$
cord-022561-rv5j1201	2195	8	surface	surface	NN
cord-022561-rv5j1201	2195	9	is	be	VBZ
cord-022561-rv5j1201	2195	10	wrinkled	wrinkled	JJ
cord-022561-rv5j1201	2195	11	,	,	,
cord-022561-rv5j1201	2195	12	and	and	CC
cord-022561-rv5j1201	2195	13	the	the	DT
cord-022561-rv5j1201	2195	14	cut	cut	NN
cord-022561-rv5j1201	2195	15	surface	surface	NN
cord-022561-rv5j1201	2195	16	is	be	VBZ
cord-022561-rv5j1201	2195	17	dry	dry	JJ
cord-022561-rv5j1201	2195	18	.	.	.
cord-022561-rv5j1201	2196	1	Hemosiderosis	Hemosiderosis	NNP
cord-022561-rv5j1201	2196	2	.	.	.
cord-022561-rv5j1201	2197	1	Hemosiderin	Hemosiderin	NNP
cord-022561-rv5j1201	2197	2	is	be	VBZ
cord-022561-rv5j1201	2197	3	a	a	DT
cord-022561-rv5j1201	2197	4	form	form	NN
cord-022561-rv5j1201	2197	5	of	of	IN
cord-022561-rv5j1201	2197	6	storage	storage	NN
cord-022561-rv5j1201	2197	7	iron	iron	NN
cord-022561-rv5j1201	2197	8	derived	derive	VBN
cord-022561-rv5j1201	2197	9	chiefly	chiefly	RB
cord-022561-rv5j1201	2197	10	from	from	IN
cord-022561-rv5j1201	2197	11	the	the	DT
cord-022561-rv5j1201	2197	12	breakdown	breakdown	NN
cord-022561-rv5j1201	2197	13	of	of	IN
cord-022561-rv5j1201	2197	14	erythrocytes	erythrocyte	NNS
cord-022561-rv5j1201	2197	15	,	,	,
cord-022561-rv5j1201	2197	16	which	which	WDT
cord-022561-rv5j1201	2197	17	normally	normally	RB
cord-022561-rv5j1201	2197	18	takes	take	VBZ
cord-022561-rv5j1201	2197	19	place	place	NN
cord-022561-rv5j1201	2197	20	in	in	IN
cord-022561-rv5j1201	2197	21	the	the	DT
cord-022561-rv5j1201	2197	22	splenic	splenic	JJ
cord-022561-rv5j1201	2197	23	red	red	JJ
cord-022561-rv5j1201	2197	24	pulp	pulp	NN
cord-022561-rv5j1201	2197	25	.	.	.
cord-022561-rv5j1201	2198	1	Thus	thus	RB
cord-022561-rv5j1201	2198	2	some	some	DT
cord-022561-rv5j1201	2198	3	splenic	splenic	JJ
cord-022561-rv5j1201	2198	4	hemosiderosis	hemosiderosis	NN
cord-022561-rv5j1201	2198	5	is	be	VBZ
cord-022561-rv5j1201	2198	6	to	to	TO
cord-022561-rv5j1201	2198	7	be	be	VB
cord-022561-rv5j1201	2198	8	expected	expect	VBN
cord-022561-rv5j1201	2198	9	,	,	,
cord-022561-rv5j1201	2198	10	and	and	CC
cord-022561-rv5j1201	2198	11	the	the	DT
cord-022561-rv5j1201	2198	12	amount	amount	NN
cord-022561-rv5j1201	2198	13	varies	vary	VBZ
cord-022561-rv5j1201	2198	14	with	with	IN
cord-022561-rv5j1201	2198	15	the	the	DT
cord-022561-rv5j1201	2198	16	species	specie	NNS
cord-022561-rv5j1201	2198	17	(	(	-LRB-
cord-022561-rv5j1201	2198	18	it	-PRON-	PRP
cord-022561-rv5j1201	2198	19	is	be	VBZ
cord-022561-rv5j1201	2198	20	most	most	RBS
cord-022561-rv5j1201	2198	21	extensive	extensive	JJ
cord-022561-rv5j1201	2198	22	in	in	IN
cord-022561-rv5j1201	2198	23	the	the	DT
cord-022561-rv5j1201	2198	24	horse	horse	NN
cord-022561-rv5j1201	2198	25	)	)	-RRB-
cord-022561-rv5j1201	2198	26	.	.	.
cord-022561-rv5j1201	2199	1	Excessive	excessive	JJ
cord-022561-rv5j1201	2199	2	amounts	amount	NNS
cord-022561-rv5j1201	2199	3	of	of	IN
cord-022561-rv5j1201	2199	4	splenic	splenic	JJ
cord-022561-rv5j1201	2199	5	hemosiderin	hemosiderin	NNP
cord-022561-rv5j1201	2199	6	are	be	VBP
cord-022561-rv5j1201	2199	7	seen	see	VBN
cord-022561-rv5j1201	2199	8	when	when	WRB
cord-022561-rv5j1201	2199	9	erythropoiesis	erythropoiesis	NNP
cord-022561-rv5j1201	2199	10	is	be	VBZ
cord-022561-rv5j1201	2199	11	reduced	reduce	VBN
cord-022561-rv5j1201	2199	12	(	(	-LRB-
cord-022561-rv5j1201	2199	13	less	less	JJR
cord-022561-rv5j1201	2199	14	demand	demand	NN
cord-022561-rv5j1201	2199	15	for	for	IN
cord-022561-rv5j1201	2199	16	iron	iron	NN
cord-022561-rv5j1201	2199	17	)	)	-RRB-
cord-022561-rv5j1201	2199	18	or	or	CC
cord-022561-rv5j1201	2199	19	from	from	IN
cord-022561-rv5j1201	2199	20	the	the	DT
cord-022561-rv5j1201	2199	21	rapid	rapid	JJ
cord-022561-rv5j1201	2199	22	destruction	destruction	NN
cord-022561-rv5j1201	2199	23	of	of	IN
cord-022561-rv5j1201	2199	24	erythrocytes	erythrocyte	NNS
cord-022561-rv5j1201	2199	25	in	in	IN
cord-022561-rv5j1201	2199	26	hemolytic	hemolytic	JJ
cord-022561-rv5j1201	2199	27	anemias	anemia	NNS
cord-022561-rv5j1201	2199	28	(	(	-LRB-
cord-022561-rv5j1201	2199	29	increased	increase	VBN
cord-022561-rv5j1201	2199	30	stores	store	NNS
cord-022561-rv5j1201	2199	31	of	of	IN
cord-022561-rv5j1201	2199	32	iron	iron	NN
cord-022561-rv5j1201	2199	33	)	)	-RRB-
cord-022561-rv5j1201	2199	34	,	,	,
cord-022561-rv5j1201	2199	35	such	such	JJ
cord-022561-rv5j1201	2199	36	as	as	IN
cord-022561-rv5j1201	2199	37	those	those	DT
cord-022561-rv5j1201	2199	38	caused	cause	VBN
cord-022561-rv5j1201	2199	39	by	by	IN
cord-022561-rv5j1201	2199	40	immune	immune	NN
cord-022561-rv5j1201	2199	41	-	-	HYPH
cord-022561-rv5j1201	2199	42	mediated	mediate	VBN
cord-022561-rv5j1201	2199	43	hemolytic	hemolytic	JJ
cord-022561-rv5j1201	2199	44	anemias	anemia	NNS
cord-022561-rv5j1201	2199	45	or	or	CC
cord-022561-rv5j1201	2199	46	hemotropic	hemotropic	NNP
cord-022561-rv5j1201	2199	47	parasites	parasite	NNS
cord-022561-rv5j1201	2199	48	.	.	.
cord-022561-rv5j1201	2200	1	Excess	excess	JJ
cord-022561-rv5j1201	2200	2	splenic	splenic	JJ
cord-022561-rv5j1201	2200	3	hemosiderin	hemosiderin	NN
cord-022561-rv5j1201	2200	4	may	may	MD
cord-022561-rv5j1201	2200	5	also	also	RB
cord-022561-rv5j1201	2200	6	occur	occur	VB
cord-022561-rv5j1201	2200	7	in	in	IN
cord-022561-rv5j1201	2200	8	conditions	condition	NNS
cord-022561-rv5j1201	2200	9	such	such	JJ
cord-022561-rv5j1201	2200	10	as	as	IN
cord-022561-rv5j1201	2200	11	chronic	chronic	JJ
cord-022561-rv5j1201	2200	12	heart	heart	NN
cord-022561-rv5j1201	2200	13	failure	failure	NN
cord-022561-rv5j1201	2200	14	or	or	CC
cord-022561-rv5j1201	2200	15	injections	injection	NNS
cord-022561-rv5j1201	2200	16	of	of	IN
cord-022561-rv5j1201	2200	17	iron	iron	NN
cord-022561-rv5j1201	2200	18	dextran	dextran	NN
cord-022561-rv5j1201	2200	19	or	or	CC
cord-022561-rv5j1201	2200	20	as	as	IN
cord-022561-rv5j1201	2200	21	focal	focal	JJ
cord-022561-rv5j1201	2200	22	accumulations	accumulation	NNS
cord-022561-rv5j1201	2200	23	at	at	IN
cord-022561-rv5j1201	2200	24	the	the	DT
cord-022561-rv5j1201	2200	25	sites	site	NNS
cord-022561-rv5j1201	2200	26	of	of	IN
cord-022561-rv5j1201	2200	27	old	old	JJ
cord-022561-rv5j1201	2200	28	hematomas	hematoma	NNS
cord-022561-rv5j1201	2200	29	,	,	,
cord-022561-rv5j1201	2200	30	infarcts	infarct	NNS
cord-022561-rv5j1201	2200	31	,	,	,
cord-022561-rv5j1201	2200	32	or	or	CC
cord-022561-rv5j1201	2200	33	trauma	trauma	NN
cord-022561-rv5j1201	2200	34	-	-	HYPH
cord-022561-rv5j1201	2200	35	induced	induce	VBN
cord-022561-rv5j1201	2200	36	hemorrhages	hemorrhage	NNS
cord-022561-rv5j1201	2200	37	.	.	.
cord-022561-rv5j1201	2201	1	Hemosiderin	Hemosiderin	NNP
cord-022561-rv5j1201	2201	2	is	be	VBZ
cord-022561-rv5j1201	2201	3	also	also	RB
cord-022561-rv5j1201	2201	4	present	present	JJ
cord-022561-rv5j1201	2201	5	in	in	IN
cord-022561-rv5j1201	2201	6	siderofibrotic	siderofibrotic	JJ
cord-022561-rv5j1201	2201	7	plaques	plaque	NNS
cord-022561-rv5j1201	2201	8	.	.	.
cord-022561-rv5j1201	2202	1	Siderofibrotic	Siderofibrotic	NNP
cord-022561-rv5j1201	2202	2	Plaques	plaque	NNS
cord-022561-rv5j1201	2202	3	.	.	.
cord-022561-rv5j1201	2203	1	Siderofibrotic	siderofibrotic	JJ
cord-022561-rv5j1201	2203	2	plaques	plaque	NNS
cord-022561-rv5j1201	2203	3	are	be	VBP
cord-022561-rv5j1201	2203	4	also	also	RB
cord-022561-rv5j1201	2203	5	known	know	VBN
cord-022561-rv5j1201	2203	6	as	as	IN
cord-022561-rv5j1201	2203	7	siderocalcific	siderocalcific	NNP
cord-022561-rv5j1201	2203	8	plaques	plaque	NNS
cord-022561-rv5j1201	2203	9	and	and	CC
cord-022561-rv5j1201	2203	10	Gamna	Gamna	NNP
cord-022561-rv5j1201	2203	11	-	-	HYPH
cord-022561-rv5j1201	2203	12	Gandy	Gandy	NNP
cord-022561-rv5j1201	2203	13	bodies	body	NNS
cord-022561-rv5j1201	2203	14	.	.	.
cord-022561-rv5j1201	2204	1	Grossly	grossly	RB
cord-022561-rv5j1201	2204	2	,	,	,
cord-022561-rv5j1201	2204	3	they	-PRON-	PRP
cord-022561-rv5j1201	2204	4	are	be	VBP
cord-022561-rv5j1201	2204	5	gray	gray	JJ
cord-022561-rv5j1201	2204	6	-	-	HYPH
cord-022561-rv5j1201	2204	7	white	white	JJ
cord-022561-rv5j1201	2204	8	to	to	IN
cord-022561-rv5j1201	2204	9	yellowish	yellowish	NN
cord-022561-rv5j1201	2204	10	,	,	,
cord-022561-rv5j1201	2204	11	firm	firm	JJ
cord-022561-rv5j1201	2204	12	,	,	,
cord-022561-rv5j1201	2204	13	dry	dry	JJ
cord-022561-rv5j1201	2204	14	encrustations	encrustation	NNS
cord-022561-rv5j1201	2204	15	on	on	IN
cord-022561-rv5j1201	2204	16	the	the	DT
cord-022561-rv5j1201	2204	17	splenic	splenic	JJ
cord-022561-rv5j1201	2204	18	capsule	capsule	NN
cord-022561-rv5j1201	2204	19	.	.	.
cord-022561-rv5j1201	2205	1	Usually	usually	RB
cord-022561-rv5j1201	2205	2	they	-PRON-	PRP
cord-022561-rv5j1201	2205	3	are	be	VBP
cord-022561-rv5j1201	2205	4	most	most	RBS
cord-022561-rv5j1201	2205	5	extensive	extensive	JJ
cord-022561-rv5j1201	2205	6	along	along	IN
cord-022561-rv5j1201	2205	7	the	the	DT
cord-022561-rv5j1201	2205	8	margins	margin	NNS
cord-022561-rv5j1201	2205	9	of	of	IN
cord-022561-rv5j1201	2205	10	the	the	DT
cord-022561-rv5j1201	2205	11	spleen	spleen	NNS
cord-022561-rv5j1201	2205	12	but	but	CC
cord-022561-rv5j1201	2205	13	can	can	MD
cord-022561-rv5j1201	2205	14	be	be	VB
cord-022561-rv5j1201	2205	15	elsewhere	elsewhere	RB
cord-022561-rv5j1201	2205	16	on	on	IN
cord-022561-rv5j1201	2205	17	the	the	DT
cord-022561-rv5j1201	2205	18	capsule	capsule	NN
cord-022561-rv5j1201	2206	1	(	(	-LRB-
cord-022561-rv5j1201	2206	2	Fig	Fig	NNP
cord-022561-rv5j1201	2206	3	.	.	NNP
cord-022561-rv5j1201	2206	4	13	13	CD
cord-022561-rv5j1201	2206	5	-	-	SYM
cord-022561-rv5j1201	2206	6	71	71	CD
cord-022561-rv5j1201	2206	7	)	)	-RRB-
cord-022561-rv5j1201	2207	1	and	and	CC
cord-022561-rv5j1201	2207	2	sometimes	sometimes	RB
cord-022561-rv5j1201	2207	3	in	in	IN
cord-022561-rv5j1201	2207	4	the	the	DT
cord-022561-rv5j1201	2207	5	parenchyma	parenchyma	NN
cord-022561-rv5j1201	2207	6	.	.	.
cord-022561-rv5j1201	2208	1	With	with	IN
cord-022561-rv5j1201	2208	2	H&E	H&E	NNP
cord-022561-rv5j1201	2208	3	staining	stain	VBG
cord-022561-rv5j1201	2208	4	these	these	DT
cord-022561-rv5j1201	2208	5	plaques	plaque	NNS
cord-022561-rv5j1201	2208	6	are	be	VBP
cord-022561-rv5j1201	2208	7	a	a	DT
cord-022561-rv5j1201	2208	8	multicolored	multicolored	JJ
cord-022561-rv5j1201	2208	9	mixture	mixture	NN
cord-022561-rv5j1201	2208	10	of	of	IN
cord-022561-rv5j1201	2208	11	yellow	yellow	JJ
cord-022561-rv5j1201	2208	12	(	(	-LRB-
cord-022561-rv5j1201	2208	13	hematoidin	hematoidin	NNP
cord-022561-rv5j1201	2208	14	)	)	-RRB-
cord-022561-rv5j1201	2208	15	,	,	,
cord-022561-rv5j1201	2208	16	golden	golden	NNP
cord-022561-rv5j1201	2208	17	brown	brown	NNP
cord-022561-rv5j1201	2208	18	(	(	-LRB-
cord-022561-rv5j1201	2208	19	hemosiderin	hemosiderin	NNP
cord-022561-rv5j1201	2208	20	)	)	-RRB-
cord-022561-rv5j1201	2208	21	,	,	,
cord-022561-rv5j1201	2208	22	purple	purple	JJ
cord-022561-rv5j1201	2208	23	-	-	HYPH
cord-022561-rv5j1201	2208	24	blue	blue	JJ
cord-022561-rv5j1201	2208	25	(	(	-LRB-
cord-022561-rv5j1201	2208	26	hematoxylinophilic	hematoxylinophilic	NNP
cord-022561-rv5j1201	2208	27	calcium	calcium	NN
cord-022561-rv5j1201	2208	28	mineral	mineral	NN
cord-022561-rv5j1201	2208	29	)	)	-RRB-
cord-022561-rv5j1201	2208	30	,	,	,
cord-022561-rv5j1201	2208	31	and	and	CC
cord-022561-rv5j1201	2208	32	pink	pink	JJ
cord-022561-rv5j1201	2208	33	(	(	-LRB-
cord-022561-rv5j1201	2208	34	eosinophilic	eosinophilic	JJ
cord-022561-rv5j1201	2208	35	fibrous	fibrous	JJ
cord-022561-rv5j1201	2208	36	tissue	tissue	NN
cord-022561-rv5j1201	2208	37	)	)	-RRB-
cord-022561-rv5j1201	2209	1	(	(	-LRB-
cord-022561-rv5j1201	2209	2	Fig	Fig	NNP
cord-022561-rv5j1201	2209	3	.	.	.
cord-022561-rv5j1201	2209	4	13	13	CD
cord-022561-rv5j1201	2209	5	-	-	SYM
cord-022561-rv5j1201	2209	6	72	72	CD
cord-022561-rv5j1201	2209	7	 	 	_SP
cord-022561-rv5j1201	2210	1	The	the	DT
cord-022561-rv5j1201	2210	2	diseases	disease	NNS
cord-022561-rv5j1201	2210	3	or	or	CC
cord-022561-rv5j1201	2210	4	conditions	condition	NNS
cord-022561-rv5j1201	2210	5	with	with	IN
cord-022561-rv5j1201	2210	6	small	small	JJ
cord-022561-rv5j1201	2210	7	lymph	lymph	NN
cord-022561-rv5j1201	2210	8	nodes	node	NNS
cord-022561-rv5j1201	2210	9	are	be	VBP
cord-022561-rv5j1201	2210	10	(	(	-LRB-
cord-022561-rv5j1201	2210	11	1	1	CD
cord-022561-rv5j1201	2210	12	)	)	-RRB-
cord-022561-rv5j1201	2210	13	congenital	congenital	JJ
cord-022561-rv5j1201	2210	14	disorders	disorder	NNS
cord-022561-rv5j1201	2210	15	,	,	,
cord-022561-rv5j1201	2210	16	(	(	-LRB-
cord-022561-rv5j1201	2210	17	2	2	LS
cord-022561-rv5j1201	2210	18	)	)	-RRB-
cord-022561-rv5j1201	2210	19	lack	lack	NN
cord-022561-rv5j1201	2210	20	of	of	IN
cord-022561-rv5j1201	2210	21	antigenic	antigenic	JJ
cord-022561-rv5j1201	2210	22	stimulation	stimulation	NN
cord-022561-rv5j1201	2210	23	,	,	,
cord-022561-rv5j1201	2210	24	(	(	-LRB-
cord-022561-rv5j1201	2210	25	3	3	LS
cord-022561-rv5j1201	2210	26	)	)	-RRB-
cord-022561-rv5j1201	2210	27	viral	viral	JJ
cord-022561-rv5j1201	2210	28	infections	infection	NNS
cord-022561-rv5j1201	2210	29	,	,	,
cord-022561-rv5j1201	2210	30	(	(	-LRB-
cord-022561-rv5j1201	2210	31	4	4	LS
cord-022561-rv5j1201	2210	32	)	)	-RRB-
cord-022561-rv5j1201	2210	33	cachexia	cachexia	NN
cord-022561-rv5j1201	2210	34	and	and	CC
cord-022561-rv5j1201	2210	35	malnutrition	malnutrition	NN
cord-022561-rv5j1201	2210	36	,	,	,
cord-022561-rv5j1201	2210	37	(	(	-LRB-
cord-022561-rv5j1201	2210	38	5	5	LS
cord-022561-rv5j1201	2210	39	)	)	-RRB-
cord-022561-rv5j1201	2210	40	aging	aging	NN
cord-022561-rv5j1201	2210	41	,	,	,
cord-022561-rv5j1201	2210	42	and	and	CC
cord-022561-rv5j1201	2210	43	(	(	-LRB-
cord-022561-rv5j1201	2210	44	6	6	CD
cord-022561-rv5j1201	2210	45	)	)	-RRB-
cord-022561-rv5j1201	2210	46	radiation	radiation	NN
cord-022561-rv5j1201	2210	47	.	.	.
cord-022561-rv5j1201	2211	1	Congenital	congenital	JJ
cord-022561-rv5j1201	2211	2	Disorders	disorder	NNS
cord-022561-rv5j1201	2211	3	.	.	.
cord-022561-rv5j1201	2212	1	Primary	primary	JJ
cord-022561-rv5j1201	2212	2	immunodeficiency	immunodeficiency	NN
cord-022561-rv5j1201	2212	3	diseases	disease	NNS
cord-022561-rv5j1201	2212	4	are	be	VBP
cord-022561-rv5j1201	2212	5	described	describe	VBN
cord-022561-rv5j1201	2212	6	in	in	IN
cord-022561-rv5j1201	2212	7	detail	detail	NN
cord-022561-rv5j1201	2212	8	in	in	IN
cord-022561-rv5j1201	2212	9	Chapter	chapter	NN
cord-022561-rv5j1201	2212	10	5	5	CD
cord-022561-rv5j1201	2212	11	and	and	CC
cord-022561-rv5j1201	2212	12	in	in	IN
cord-022561-rv5j1201	2212	13	the	the	DT
cord-022561-rv5j1201	2212	14	sections	section	NNS
cord-022561-rv5j1201	2212	15	on	on	IN
cord-022561-rv5j1201	2212	16	Disorders	disorder	NNS
cord-022561-rv5j1201	2212	17	of	of	IN
cord-022561-rv5j1201	2212	18	Horses	horse	NNS
cord-022561-rv5j1201	2212	19	and	and	CC
cord-022561-rv5j1201	2212	20	Disorders	disorder	NNS
cord-022561-rv5j1201	2212	21	of	of	IN
cord-022561-rv5j1201	2212	22	Dogs	dog	NNS
cord-022561-rv5j1201	2212	23	.	.	.
cord-022561-rv5j1201	2213	1	Neonatal	neonatal	JJ
cord-022561-rv5j1201	2213	2	animals	animal	NNS
cord-022561-rv5j1201	2213	3	with	with	IN
cord-022561-rv5j1201	2213	4	primary	primary	JJ
cord-022561-rv5j1201	2213	5	immunodeficiency	immunodeficiency	NN
cord-022561-rv5j1201	2213	6	diseases	disease	NNS
cord-022561-rv5j1201	2213	7	often	often	RB
cord-022561-rv5j1201	2213	8	have	have	VBP
cord-022561-rv5j1201	2213	9	extremely	extremely	RB
cord-022561-rv5j1201	2213	10	small	small	JJ
cord-022561-rv5j1201	2213	11	to	to	IN
cord-022561-rv5j1201	2213	12	undetectable	undetectable	JJ
cord-022561-rv5j1201	2213	13	lymph	lymph	NN
cord-022561-rv5j1201	2213	14	nodes	node	NNS
cord-022561-rv5j1201	2213	15	.	.	.
cord-022561-rv5j1201	2214	1	In	in	IN
cord-022561-rv5j1201	2214	2	dogs	dog	NNS
cord-022561-rv5j1201	2214	3	and	and	CC
cord-022561-rv5j1201	2214	4	horses	horse	NNS
cord-022561-rv5j1201	2214	5	with	with	IN
cord-022561-rv5j1201	2214	6	severe	severe	JJ
cord-022561-rv5j1201	2214	7	combined	combine	VBN
cord-022561-rv5j1201	2214	8	immunodeficiency	immunodeficiency	NN
cord-022561-rv5j1201	2214	9	disease	disease	NN
cord-022561-rv5j1201	2214	10	(	(	-LRB-
cord-022561-rv5j1201	2214	11	SCID	SCID	NNP
cord-022561-rv5j1201	2214	12	)	)	-RRB-
cord-022561-rv5j1201	2214	13	,	,	,
cord-022561-rv5j1201	2214	14	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	2214	15	tissues	tissue	NNS
cord-022561-rv5j1201	2214	16	,	,	,
cord-022561-rv5j1201	2214	17	including	include	VBG
cord-022561-rv5j1201	2214	18	lymph	lymph	NN
cord-022561-rv5j1201	2214	19	nodes	node	NNS
cord-022561-rv5j1201	2214	20	from	from	IN
cord-022561-rv5j1201	2214	21	affected	affect	VBN
cord-022561-rv5j1201	2214	22	animals	animal	NNS
cord-022561-rv5j1201	2214	23	,	,	,
cord-022561-rv5j1201	2214	24	are	be	VBP
cord-022561-rv5j1201	2214	25	often	often	RB
cord-022561-rv5j1201	2214	26	grossly	grossly	RB
cord-022561-rv5j1201	2214	27	difficult	difficult	JJ
cord-022561-rv5j1201	2214	28	to	to	TO
cord-022561-rv5j1201	2214	29	identify	identify	VB
cord-022561-rv5j1201	2214	30	and	and	CC
cord-022561-rv5j1201	2214	31	characterized	characterize	VBN
cord-022561-rv5j1201	2214	32	by	by	IN
cord-022561-rv5j1201	2214	33	an	an	DT
cord-022561-rv5j1201	2214	34	absence	absence	NN
cord-022561-rv5j1201	2214	35	of	of	IN
cord-022561-rv5j1201	2214	36	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	2214	37	follicles	follicle	NNS
cord-022561-rv5j1201	2214	38	.	.	.
cord-022561-rv5j1201	2215	1	Congenital	Congenital	NNP
cord-022561-rv5j1201	2215	2	may	may	MD
cord-022561-rv5j1201	2215	3	represent	represent	VB
cord-022561-rv5j1201	2215	4	sequelae	sequela	NNS
cord-022561-rv5j1201	2215	5	to	to	IN
cord-022561-rv5j1201	2215	6	previous	previous	JJ
cord-022561-rv5j1201	2215	7	hemorrhages	hemorrhage	NNS
cord-022561-rv5j1201	2215	8	from	from	IN
cord-022561-rv5j1201	2215	9	trauma	trauma	NN
cord-022561-rv5j1201	2215	10	to	to	IN
cord-022561-rv5j1201	2215	11	the	the	DT
cord-022561-rv5j1201	2215	12	spleen	spleen	NN
cord-022561-rv5j1201	2215	13	.	.	.
cord-022561-rv5j1201	2216	1	Splenic	Splenic	NNP
cord-022561-rv5j1201	2216	2	Rupture	Rupture	NNP
cord-022561-rv5j1201	2216	3	.	.	.
cord-022561-rv5j1201	2217	1	Splenic	splenic	JJ
cord-022561-rv5j1201	2217	2	rupture	rupture	NN
cord-022561-rv5j1201	2217	3	is	be	VBZ
cord-022561-rv5j1201	2217	4	most	most	RBS
cord-022561-rv5j1201	2217	5	commonly	commonly	RB
cord-022561-rv5j1201	2217	6	caused	cause	VBN
cord-022561-rv5j1201	2217	7	by	by	IN
cord-022561-rv5j1201	2217	8	trauma	trauma	NN
cord-022561-rv5j1201	2217	9	,	,	,
cord-022561-rv5j1201	2217	10	such	such	JJ
cord-022561-rv5j1201	2217	11	as	as	IN
cord-022561-rv5j1201	2217	12	from	from	IN
cord-022561-rv5j1201	2217	13	an	an	DT
cord-022561-rv5j1201	2217	14	automobile	automobile	NN
cord-022561-rv5j1201	2217	15	accident	accident	NN
cord-022561-rv5j1201	2217	16	or	or	CC
cord-022561-rv5j1201	2217	17	being	be	VBG
cord-022561-rv5j1201	2217	18	kicked	kick	VBN
cord-022561-rv5j1201	2217	19	by	by	IN
cord-022561-rv5j1201	2217	20	other	other	JJ
cord-022561-rv5j1201	2217	21	animals	animal	NNS
cord-022561-rv5j1201	2217	22	.	.	.
cord-022561-rv5j1201	2218	1	Thinning	thin	VBG
cord-022561-rv5j1201	2218	2	of	of	IN
cord-022561-rv5j1201	2218	3	the	the	DT
cord-022561-rv5j1201	2218	4	capsule	capsule	NN
cord-022561-rv5j1201	2218	5	from	from	IN
cord-022561-rv5j1201	2218	6	splenomegaly	splenomegaly	NN
cord-022561-rv5j1201	2218	7	can	can	MD
cord-022561-rv5j1201	2218	8	render	render	VB
cord-022561-rv5j1201	2218	9	the	the	DT
cord-022561-rv5j1201	2218	10	spleen	spleen	NN
cord-022561-rv5j1201	2218	11	more	more	RBR
cord-022561-rv5j1201	2218	12	susceptible	susceptible	JJ
cord-022561-rv5j1201	2218	13	to	to	IN
cord-022561-rv5j1201	2218	14	rupture	rupture	NN
cord-022561-rv5j1201	2218	15	,	,	,
cord-022561-rv5j1201	2218	16	and	and	CC
cord-022561-rv5j1201	2218	17	this	this	DT
cord-022561-rv5j1201	2218	18	may	may	MD
cord-022561-rv5j1201	2218	19	occur	occur	VB
cord-022561-rv5j1201	2218	20	at	at	IN
cord-022561-rv5j1201	2218	21	sites	site	NNS
cord-022561-rv5j1201	2218	22	of	of	IN
cord-022561-rv5j1201	2218	23	infarcts	infarct	NNS
cord-022561-rv5j1201	2218	24	,	,	,
cord-022561-rv5j1201	2218	25	hematomas	hematoma	NNS
cord-022561-rv5j1201	2218	26	,	,	,
cord-022561-rv5j1201	2218	27	hemangiosarcomas	hemangiosarcomas	NN
cord-022561-rv5j1201	2218	28	,	,	,
cord-022561-rv5j1201	2218	29	and	and	CC
cord-022561-rv5j1201	2218	30	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2218	31	.	.	.
cord-022561-rv5j1201	2219	1	In	in	IN
cord-022561-rv5j1201	2219	2	acute	acute	JJ
cord-022561-rv5j1201	2219	3	cases	case	NNS
cord-022561-rv5j1201	2219	4	of	of	IN
cord-022561-rv5j1201	2219	5	splenic	splenic	JJ
cord-022561-rv5j1201	2219	6	capsular	capsular	JJ
cord-022561-rv5j1201	2219	7	rupture	rupture	NN
cord-022561-rv5j1201	2219	8	,	,	,
cord-022561-rv5j1201	2219	9	the	the	DT
cord-022561-rv5j1201	2219	10	spleen	spleen	NN
cord-022561-rv5j1201	2219	11	is	be	VBZ
cord-022561-rv5j1201	2219	12	contracted	contract	VBN
cord-022561-rv5j1201	2219	13	and	and	CC
cord-022561-rv5j1201	2219	14	dry	dry	JJ
cord-022561-rv5j1201	2219	15	and	and	CC
cord-022561-rv5j1201	2219	16	the	the	DT
cord-022561-rv5j1201	2219	17	surface	surface	NN
cord-022561-rv5j1201	2219	18	wrinkled	wrinkle	VBN
cord-022561-rv5j1201	2219	19	from	from	IN
cord-022561-rv5j1201	2219	20	the	the	DT
cord-022561-rv5j1201	2219	21	marked	marked	JJ
cord-022561-rv5j1201	2219	22	blood	blood	NN
cord-022561-rv5j1201	2219	23	loss	loss	NN
cord-022561-rv5j1201	2219	24	(	(	-LRB-
cord-022561-rv5j1201	2219	25	Fig	fig	NN
cord-022561-rv5j1201	2219	26	.	.	.
cord-022561-rv5j1201	2219	27	 	 	_SP
cord-022561-rv5j1201	2219	28	13	13	CD
cord-022561-rv5j1201	2219	29	-	-	SYM
cord-022561-rv5j1201	2219	30	73	73	CD
cord-022561-rv5j1201	2219	31	)	)	-RRB-
cord-022561-rv5j1201	2219	32	.	.	.
cord-022561-rv5j1201	2220	1	In	in	IN
cord-022561-rv5j1201	2220	2	more	more	RBR
cord-022561-rv5j1201	2220	3	severe	severe	JJ
cord-022561-rv5j1201	2220	4	cases	case	NNS
cord-022561-rv5j1201	2220	5	the	the	DT
cord-022561-rv5j1201	2220	6	spleen	spleen	NN
cord-022561-rv5j1201	2220	7	may	may	MD
cord-022561-rv5j1201	2220	8	be	be	VB
cord-022561-rv5j1201	2220	9	broken	break	VBN
cord-022561-rv5j1201	2220	10	into	into	IN
cord-022561-rv5j1201	2220	11	two	two	CD
cord-022561-rv5j1201	2220	12	or	or	CC
cord-022561-rv5j1201	2220	13	more	more	JJR
cord-022561-rv5j1201	2220	14	pieces	piece	NNS
cord-022561-rv5j1201	2220	15	,	,	,
cord-022561-rv5j1201	2220	16	and	and	CC
cord-022561-rv5j1201	2220	17	small	small	JJ
cord-022561-rv5j1201	2220	18	pieces	piece	NNS
cord-022561-rv5j1201	2220	19	of	of	IN
cord-022561-rv5j1201	2220	20	splenic	splenic	JJ
cord-022561-rv5j1201	2220	21	parenchyma	parenchyma	NN
cord-022561-rv5j1201	2220	22	may	may	MD
cord-022561-rv5j1201	2220	23	be	be	VB
cord-022561-rv5j1201	2220	24	scattered	scatter	VBN
cord-022561-rv5j1201	2220	25	throughout	throughout	IN
cord-022561-rv5j1201	2220	26	the	the	DT
cord-022561-rv5j1201	2220	27	omentum	omentum	NN
cord-022561-rv5j1201	2220	28	and	and	CC
cord-022561-rv5j1201	2220	29	peritoneum	peritoneum	NN
cord-022561-rv5j1201	2220	30	(	(	-LRB-
cord-022561-rv5j1201	2220	31	sometimes	sometimes	RB
cord-022561-rv5j1201	2220	32	called	call	VBN
cord-022561-rv5j1201	2220	33	splenosis	splenosis	NNP
cord-022561-rv5j1201	2220	34	)	)	-RRB-
cord-022561-rv5j1201	2221	1	(	(	-LRB-
cord-022561-rv5j1201	2221	2	Fig	Fig	NNP
cord-022561-rv5j1201	2221	3	.	.	NNP
cord-022561-rv5j1201	2221	4	13	13	CD
cord-022561-rv5j1201	2221	5	-	-	SYM
cord-022561-rv5j1201	2221	6	74	74	CD
cord-022561-rv5j1201	2221	7	,	,	,
cord-022561-rv5j1201	2221	8	A	A	NNP
cord-022561-rv5j1201	2221	9	)	)	-RRB-
cord-022561-rv5j1201	2221	10	.	.	.
cord-022561-rv5j1201	2222	1	Clotted	clotted	JJ
cord-022561-rv5j1201	2222	2	blood	blood	NN
cord-022561-rv5j1201	2222	3	,	,	,
cord-022561-rv5j1201	2222	4	fibrin	fibrin	NN
cord-022561-rv5j1201	2222	5	,	,	,
cord-022561-rv5j1201	2222	6	and	and	CC
cord-022561-rv5j1201	2222	7	omentum	omentum	NN
cord-022561-rv5j1201	2222	8	may	may	MD
cord-022561-rv5j1201	2222	9	adhere	adhere	VB
cord-022561-rv5j1201	2222	10	to	to	IN
cord-022561-rv5j1201	2222	11	the	the	DT
cord-022561-rv5j1201	2222	12	surface	surface	NN
cord-022561-rv5j1201	2222	13	at	at	IN
cord-022561-rv5j1201	2222	14	the	the	DT
cord-022561-rv5j1201	2222	15	rupture	rupture	NN
cord-022561-rv5j1201	2222	16	site	site	NN
cord-022561-rv5j1201	2222	17	.	.	.
cord-022561-rv5j1201	2223	1	If	if	IN
cord-022561-rv5j1201	2223	2	the	the	DT
cord-022561-rv5j1201	2223	3	rupture	rupture	NN
cord-022561-rv5j1201	2223	4	is	be	VBZ
cord-022561-rv5j1201	2223	5	not	not	RB
cord-022561-rv5j1201	2223	6	fatal	fatal	JJ
cord-022561-rv5j1201	2223	7	,	,	,
cord-022561-rv5j1201	2223	8	the	the	DT
cord-022561-rv5j1201	2223	9	spleen	spleen	NN
cord-022561-rv5j1201	2223	10	heals	heal	VBZ
cord-022561-rv5j1201	2223	11	by	by	IN
cord-022561-rv5j1201	2223	12	fibrosis	fibrosis	NN
cord-022561-rv5j1201	2223	13	,	,	,
cord-022561-rv5j1201	2223	14	and	and	CC
cord-022561-rv5j1201	2223	15	there	there	EX
cord-022561-rv5j1201	2223	16	may	may	MD
cord-022561-rv5j1201	2223	17	be	be	VB
cord-022561-rv5j1201	2223	18	a	a	DT
cord-022561-rv5j1201	2223	19	capsular	capsular	JJ
cord-022561-rv5j1201	2223	20	scar	scar	NN
cord-022561-rv5j1201	2223	21	.	.	.
cord-022561-rv5j1201	2224	1	Occasionally	occasionally	RB
cord-022561-rv5j1201	2224	2	there	there	EX
cord-022561-rv5j1201	2224	3	are	be	VBP
cord-022561-rv5j1201	2224	4	two	two	CD
cord-022561-rv5j1201	2224	5	or	or	CC
cord-022561-rv5j1201	2224	6	more	more	RBR
cord-022561-rv5j1201	2224	7	separate	separate	JJ
cord-022561-rv5j1201	2224	8	pieces	piece	NNS
cord-022561-rv5j1201	2224	9	of	of	IN
cord-022561-rv5j1201	2224	10	spleen	spleen	NN
cord-022561-rv5j1201	2224	11	adjacent	adjacent	JJ
cord-022561-rv5j1201	2224	12	to	to	IN
cord-022561-rv5j1201	2224	13	each	each	DT
cord-022561-rv5j1201	2224	14	other	other	JJ
cord-022561-rv5j1201	2224	15	and	and	CC
cord-022561-rv5j1201	2224	16	sometimes	sometimes	RB
cord-022561-rv5j1201	2224	17	joined	join	VBN
cord-022561-rv5j1201	2224	18	by	by	IN
cord-022561-rv5j1201	2224	19	scar	scar	NN
cord-022561-rv5j1201	2224	20	tissue	tissue	NN
cord-022561-rv5j1201	2224	21	in	in	IN
cord-022561-rv5j1201	2224	22	the	the	DT
cord-022561-rv5j1201	2224	23	gastrosplenic	gastrosplenic	NNP
cord-022561-rv5j1201	2224	24	ligament	ligament	NN
cord-022561-rv5j1201	2224	25	.	.	.
cord-022561-rv5j1201	2225	1	The	the	DT
cord-022561-rv5j1201	2225	2	functional	functional	JJ
cord-022561-rv5j1201	2225	3	capabilities	capability	NNS
cord-022561-rv5j1201	2225	4	of	of	IN
cord-022561-rv5j1201	2225	5	the	the	DT
cord-022561-rv5j1201	2225	6	small	small	JJ
cord-022561-rv5j1201	2225	7	accessory	accessory	NN
cord-022561-rv5j1201	2225	8	spleens	spleen	NNS
cord-022561-rv5j1201	2225	9	are	be	VBP
cord-022561-rv5j1201	2225	10	questionable	questionable	JJ
cord-022561-rv5j1201	2225	11	,	,	,
cord-022561-rv5j1201	2225	12	although	although	IN
cord-022561-rv5j1201	2225	13	erythrophagocytosis	erythrophagocytosis	NNP
cord-022561-rv5j1201	2225	14	,	,	,
cord-022561-rv5j1201	2225	15	hemosiderosis	hemosiderosis	NNP
cord-022561-rv5j1201	2225	16	,	,	,
cord-022561-rv5j1201	2225	17	hyperplastic	hyperplastic	JJ
cord-022561-rv5j1201	2225	18	nodules	nodule	NNS
cord-022561-rv5j1201	2225	19	,	,	,
cord-022561-rv5j1201	2225	20	EMH	EMH	NNP
cord-022561-rv5j1201	2225	21	,	,	,
cord-022561-rv5j1201	2225	22	and	and	CC
cord-022561-rv5j1201	2225	23	neoplasia	neoplasia	NN
cord-022561-rv5j1201	2225	24	can	can	MD
cord-022561-rv5j1201	2225	25	be	be	VB
cord-022561-rv5j1201	2225	26	present	present	JJ
cord-022561-rv5j1201	2225	27	in	in	IN
cord-022561-rv5j1201	2225	28	these	these	DT
cord-022561-rv5j1201	2225	29	nodules	nodule	NNS
cord-022561-rv5j1201	2225	30	.	.	.
cord-022561-rv5j1201	2226	1	Accessory	accessory	NN
cord-022561-rv5j1201	2226	2	spleens	spleen	NNS
cord-022561-rv5j1201	2226	3	due	due	JJ
cord-022561-rv5j1201	2226	4	to	to	IN
cord-022561-rv5j1201	2226	5	traumatic	traumatic	JJ
cord-022561-rv5j1201	2226	6	rupture	rupture	NN
cord-022561-rv5j1201	2226	7	should	should	MD
cord-022561-rv5j1201	2226	8	be	be	VB
cord-022561-rv5j1201	2226	9	distinguished	distinguish	VBN
cord-022561-rv5j1201	2226	10	from	from	IN
cord-022561-rv5j1201	2226	11	peritoneal	peritoneal	JJ
cord-022561-rv5j1201	2226	12	seeding	seeding	NN
cord-022561-rv5j1201	2226	13	of	of	IN
cord-022561-rv5j1201	2226	14	hemangiosarcoma	hemangiosarcoma	NN
cord-022561-rv5j1201	2226	15	and	and	CC
cord-022561-rv5j1201	2226	16	the	the	DT
cord-022561-rv5j1201	2226	17	developmental	developmental	JJ
cord-022561-rv5j1201	2226	18	anomaly	anomaly	NN
cord-022561-rv5j1201	2226	19	splenic	splenic	JJ
cord-022561-rv5j1201	2226	20	choristomas	choristoma	NNS
cord-022561-rv5j1201	2226	21	(	(	-LRB-
cord-022561-rv5j1201	2226	22	see	see	VB
cord-022561-rv5j1201	2226	23	Fig	Fig	NNP
cord-022561-rv5j1201	2226	24	.	.	.
cord-022561-rv5j1201	2227	1	13	13	CD
cord-022561-rv5j1201	2227	2	-	-	SYM
cord-022561-rv5j1201	2227	3	74	74	CD
cord-022561-rv5j1201	2227	4	,	,	,
cord-022561-rv5j1201	2227	5	B	B	NNP
cord-022561-rv5j1201	2227	6	)	)	-RRB-
cord-022561-rv5j1201	2227	7	,	,	,
cord-022561-rv5j1201	2227	8	which	which	WDT
cord-022561-rv5j1201	2227	9	are	be	VBP
cord-022561-rv5j1201	2227	10	nodules	nodule	NNS
cord-022561-rv5j1201	2227	11	of	of	IN
cord-022561-rv5j1201	2227	12	normal	normal	JJ
cord-022561-rv5j1201	2227	13	splenic	splenic	JJ
cord-022561-rv5j1201	2227	14	parenchyma	parenchyma	NN
cord-022561-rv5j1201	2227	15	in	in	IN
cord-022561-rv5j1201	2227	16	abnormal	abnormal	JJ
cord-022561-rv5j1201	2227	17	locations	location	NNS
cord-022561-rv5j1201	2227	18	(	(	-LRB-
cord-022561-rv5j1201	2227	19	such	such	JJ
cord-022561-rv5j1201	2227	20	as	as	IN
cord-022561-rv5j1201	2227	21	liver	liver	NN
cord-022561-rv5j1201	2227	22	and	and	CC
cord-022561-rv5j1201	2227	23	pancreas	pancreas	NN
cord-022561-rv5j1201	2227	24	)	)	-RRB-
cord-022561-rv5j1201	2227	25	.	.	.
cord-022561-rv5j1201	2228	1	Chronic	Chronic	NNP
cord-022561-rv5j1201	2228	2	Splenic	Splenic	NNP
cord-022561-rv5j1201	2228	3	Infarcts	infarct	NNS
cord-022561-rv5j1201	2228	4	.	.	.
cord-022561-rv5j1201	2229	1	In	in	IN
cord-022561-rv5j1201	2229	2	the	the	DT
cord-022561-rv5j1201	2229	3	early	early	JJ
cord-022561-rv5j1201	2229	4	stage	stage	NN
cord-022561-rv5j1201	2229	5	,	,	,
cord-022561-rv5j1201	2229	6	splenic	splenic	JJ
cord-022561-rv5j1201	2229	7	infarcts	infarct	NNS
cord-022561-rv5j1201	2229	8	are	be	VBP
cord-022561-rv5j1201	2229	9	hemorrhagic	hemorrhagic	JJ
cord-022561-rv5j1201	2229	10	and	and	CC
cord-022561-rv5j1201	2229	11	may	may	MD
cord-022561-rv5j1201	2229	12	elevate	elevate	VB
cord-022561-rv5j1201	2229	13	the	the	DT
cord-022561-rv5j1201	2229	14	capsule	capsule	NN
cord-022561-rv5j1201	2229	15	(	(	-LRB-
cord-022561-rv5j1201	2229	16	see	see	VB
cord-022561-rv5j1201	2229	17	Splenic	Splenic	NNP
cord-022561-rv5j1201	2229	18	Nodules	Nodules	NNPS
cord-022561-rv5j1201	2229	19	with	with	IN
cord-022561-rv5j1201	2229	20	a	a	DT
cord-022561-rv5j1201	2229	21	Bloody	Bloody	NNP
cord-022561-rv5j1201	2229	22	Consistency	Consistency	NNP
cord-022561-rv5j1201	2229	23	)	)	-RRB-
cord-022561-rv5j1201	2229	24	.	.	.
cord-022561-rv5j1201	2230	1	However	however	RB
cord-022561-rv5j1201	2230	2	,	,	,
cord-022561-rv5j1201	2230	3	as	as	IN
cord-022561-rv5j1201	2230	4	the	the	DT
cord-022561-rv5j1201	2230	5	lesions	lesion	NNS
cord-022561-rv5j1201	2230	6	age	age	NN
cord-022561-rv5j1201	2230	7	and	and	CC
cord-022561-rv5j1201	2230	8	fibrous	fibrous	JJ
cord-022561-rv5j1201	2230	9	connective	connective	JJ
cord-022561-rv5j1201	2230	10	tissue	tissue	NN
cord-022561-rv5j1201	2230	11	is	be	VBZ
cord-022561-rv5j1201	2230	12	laid	lay	VBN
cord-022561-rv5j1201	2230	13	down	down	RP
cord-022561-rv5j1201	2230	14	,	,	,
cord-022561-rv5j1201	2230	15	they	-PRON-	PRP
cord-022561-rv5j1201	2230	16	shrink	shrink	VBP
cord-022561-rv5j1201	2230	17	and	and	CC
cord-022561-rv5j1201	2230	18	become	become	VBP
cord-022561-rv5j1201	2230	19	contracted	contract	VBN
cord-022561-rv5j1201	2230	20	and	and	CC
cord-022561-rv5j1201	2230	21	often	often	RB
cord-022561-rv5j1201	2230	22	depressed	depressed	JJ
cord-022561-rv5j1201	2230	23	below	below	IN
cord-022561-rv5j1201	2230	24	the	the	DT
cord-022561-rv5j1201	2230	25	surface	surface	NN
cord-022561-rv5j1201	2230	26	of	of	IN
cord-022561-rv5j1201	2230	27	the	the	DT
cord-022561-rv5j1201	2230	28	adjacent	adjacent	JJ
cord-022561-rv5j1201	2230	29	capsule	capsule	NN
cord-022561-rv5j1201	2230	30	.	.	.
cord-022561-rv5j1201	2231	1	Conditions	condition	NNS
cord-022561-rv5j1201	2231	2	causing	cause	VBG
cord-022561-rv5j1201	2231	3	lymphadenomegaly	lymphadenomegaly	NNS
cord-022561-rv5j1201	2231	4	include	include	VBP
cord-022561-rv5j1201	2231	5	(	(	-LRB-
cord-022561-rv5j1201	2231	6	1	1	CD
cord-022561-rv5j1201	2231	7	)	)	-RRB-
cord-022561-rv5j1201	2231	8	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	2231	9	hyperplasia	hyperplasia	NN
cord-022561-rv5j1201	2231	10	(	(	-LRB-
cord-022561-rv5j1201	2231	11	follicular	follicular	JJ
cord-022561-rv5j1201	2231	12	or	or	CC
cord-022561-rv5j1201	2231	13	paracortical	paracortical	JJ
cord-022561-rv5j1201	2231	14	)	)	-RRB-
cord-022561-rv5j1201	2231	15	,	,	,
cord-022561-rv5j1201	2231	16	(	(	-LRB-
cord-022561-rv5j1201	2231	17	2	2	LS
cord-022561-rv5j1201	2231	18	)	)	-RRB-
cord-022561-rv5j1201	2231	19	hyperplasia	hyperplasia	NN
cord-022561-rv5j1201	2231	20	of	of	IN
cord-022561-rv5j1201	2231	21	the	the	DT
cord-022561-rv5j1201	2231	22	sinus	sinus	NNP
cord-022561-rv5j1201	2231	23	histiocytes	histiocytes	NNPS
cord-022561-rv5j1201	2231	24	(	(	-LRB-
cord-022561-rv5j1201	2231	25	monocyte	monocyte	NNP
cord-022561-rv5j1201	2231	26	-	-	HYPH
cord-022561-rv5j1201	2231	27	macrophage	macrophage	NN
cord-022561-rv5j1201	2231	28	system	system	NN
cord-022561-rv5j1201	2231	29	)	)	-RRB-
cord-022561-rv5j1201	2231	30	,	,	,
cord-022561-rv5j1201	2231	31	(	(	-LRB-
cord-022561-rv5j1201	2231	32	3	3	LS
cord-022561-rv5j1201	2231	33	)	)	-RRB-
cord-022561-rv5j1201	2231	34	acute	acute	JJ
cord-022561-rv5j1201	2231	35	or	or	CC
cord-022561-rv5j1201	2231	36	chronic	chronic	JJ
cord-022561-rv5j1201	2231	37	lymphadenitis	lymphadenitis	NN
cord-022561-rv5j1201	2231	38	,	,	,
cord-022561-rv5j1201	2231	39	(	(	-LRB-
cord-022561-rv5j1201	2231	40	4	4	LS
cord-022561-rv5j1201	2231	41	)	)	-RRB-
cord-022561-rv5j1201	2231	42	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2231	43	,	,	,
cord-022561-rv5j1201	2231	44	and	and	CC
cord-022561-rv5j1201	2231	45	(	(	-LRB-
cord-022561-rv5j1201	2231	46	5	5	LS
cord-022561-rv5j1201	2231	47	)	)	-RRB-
cord-022561-rv5j1201	2231	48	metastatic	metastatic	JJ
cord-022561-rv5j1201	2231	49	neoplasia	neoplasia	NN
cord-022561-rv5j1201	2231	50	.	.	.
cord-022561-rv5j1201	2232	1	Macrophage	Macrophage	NNP
cord-022561-rv5j1201	2232	2	System	System	NNP
cord-022561-rv5j1201	2232	3	.	.	.
cord-022561-rv5j1201	2233	1	Detailed	detailed	JJ
cord-022561-rv5j1201	2233	2	descriptions	description	NNS
cord-022561-rv5j1201	2233	3	of	of	IN
cord-022561-rv5j1201	2233	4	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	2233	5	follicular	follicular	JJ
cord-022561-rv5j1201	2233	6	hyperplasia	hyperplasia	NN
cord-022561-rv5j1201	2233	7	,	,	,
cord-022561-rv5j1201	2233	8	paracortical	paracortical	JJ
cord-022561-rv5j1201	2233	9	hyperplasia	hyperplasia	NN
cord-022561-rv5j1201	2233	10	,	,	,
cord-022561-rv5j1201	2233	11	and	and	CC
cord-022561-rv5j1201	2233	12	hyperplasia	hyperplasia	NN
cord-022561-rv5j1201	2233	13	of	of	IN
cord-022561-rv5j1201	2233	14	sinus	sinus	NN
cord-022561-rv5j1201	2233	15	histiocytes	histiocyte	NNS
cord-022561-rv5j1201	2233	16	are	be	VBP
cord-022561-rv5j1201	2233	17	in	in	IN
cord-022561-rv5j1201	2233	18	the	the	DT
cord-022561-rv5j1201	2233	19	sections	section	NNS
cord-022561-rv5j1201	2233	20	on	on	IN
cord-022561-rv5j1201	2233	21	Lymph	lymph	NN
cord-022561-rv5j1201	2233	22	Nodes	node	NNS
cord-022561-rv5j1201	2233	23	,	,	,
cord-022561-rv5j1201	2233	24	Function	function	NN
cord-022561-rv5j1201	2233	25	,	,	,
cord-022561-rv5j1201	2233	26	and	and	CC
cord-022561-rv5j1201	2233	27	Lymph	Lymph	NNP
cord-022561-rv5j1201	2233	28	Node	Node	NNP
cord-022561-rv5j1201	2233	29	,	,	,
cord-022561-rv5j1201	2233	30	Dysfunction	Dysfunction	NNP
cord-022561-rv5j1201	2233	31	/	/	SYM
cord-022561-rv5j1201	2233	32	Responses	response	NNS
cord-022561-rv5j1201	2233	33	to	to	IN
cord-022561-rv5j1201	2233	34	Injury	injury	NN
cord-022561-rv5j1201	2233	35	.	.	.
cord-022561-rv5j1201	2234	1	Follicular	follicular	JJ
cord-022561-rv5j1201	2234	2	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	2234	3	hyperplasia	hyperplasia	NN
cord-022561-rv5j1201	2234	4	can	can	MD
cord-022561-rv5j1201	2234	5	involve	involve	VB
cord-022561-rv5j1201	2234	6	large	large	JJ
cord-022561-rv5j1201	2234	7	numbers	number	NNS
cord-022561-rv5j1201	2234	8	of	of	IN
cord-022561-rv5j1201	2234	9	lymph	lymph	NN
cord-022561-rv5j1201	2234	10	nodes	node	NNS
cord-022561-rv5j1201	2234	11	,	,	,
cord-022561-rv5j1201	2234	12	as	as	IN
cord-022561-rv5j1201	2234	13	in	in	IN
cord-022561-rv5j1201	2234	14	a	a	DT
cord-022561-rv5j1201	2234	15	systemic	systemic	JJ
cord-022561-rv5j1201	2234	16	disease	disease	NN
cord-022561-rv5j1201	2234	17	,	,	,
cord-022561-rv5j1201	2234	18	or	or	CC
cord-022561-rv5j1201	2234	19	can	can	MD
cord-022561-rv5j1201	2234	20	be	be	VB
cord-022561-rv5j1201	2234	21	localized	localize	VBN
cord-022561-rv5j1201	2234	22	to	to	IN
cord-022561-rv5j1201	2234	23	a	a	DT
cord-022561-rv5j1201	2234	24	regional	regional	JJ
cord-022561-rv5j1201	2234	25	lymph	lymph	NN
cord-022561-rv5j1201	2234	26	node	node	NN
cord-022561-rv5j1201	2234	27	draining	drain	VBG
cord-022561-rv5j1201	2234	28	an	an	DT
cord-022561-rv5j1201	2234	29	inflamed	inflamed	JJ
cord-022561-rv5j1201	2234	30	or	or	CC
cord-022561-rv5j1201	2234	31	antigenically	antigenically	RB
cord-022561-rv5j1201	2234	32	stimulated	stimulate	VBN
cord-022561-rv5j1201	2234	33	(	(	-LRB-
cord-022561-rv5j1201	2234	34	e.g.	e.g.	RB
cord-022561-rv5j1201	2234	35	,	,	,
cord-022561-rv5j1201	2234	36	vaccine	vaccine	NN
cord-022561-rv5j1201	2234	37	injection	injection	NN
cord-022561-rv5j1201	2234	38	)	)	-RRB-
cord-022561-rv5j1201	2234	39	area	area	NN
cord-022561-rv5j1201	2234	40	.	.	.
cord-022561-rv5j1201	2235	1	Acute	Acute	NNP
cord-022561-rv5j1201	2235	2	Lymphadenitis	Lymphadenitis	NNP
cord-022561-rv5j1201	2235	3	.	.	.
cord-022561-rv5j1201	2236	1	Lymph	lymph	NN
cord-022561-rv5j1201	2236	2	nodes	node	NNS
cord-022561-rv5j1201	2236	3	draining	drain	VBG
cord-022561-rv5j1201	2236	4	sites	site	NNS
cord-022561-rv5j1201	2236	5	of	of	IN
cord-022561-rv5j1201	2236	6	infection	infection	NN
cord-022561-rv5j1201	2236	7	and	and	CC
cord-022561-rv5j1201	2236	8	inflammation	inflammation	NN
cord-022561-rv5j1201	2236	9	may	may	MD
cord-022561-rv5j1201	2236	10	develop	develop	VB
cord-022561-rv5j1201	2236	11	acute	acute	JJ
cord-022561-rv5j1201	2236	12	lymphadenitis	lymphadenitis	NN
cord-022561-rv5j1201	2236	13	(	(	-LRB-
cord-022561-rv5j1201	2236	14	e.g.	e.g.	RB
cord-022561-rv5j1201	2236	15	,	,	,
cord-022561-rv5j1201	2236	16	retropharyngeal	retropharyngeal	JJ
cord-022561-rv5j1201	2236	17	lymph	lymph	NN
cord-022561-rv5j1201	2236	18	nodes	node	NNS
cord-022561-rv5j1201	2236	19	draining	drain	VBG
cord-022561-rv5j1201	2236	20	the	the	DT
cord-022561-rv5j1201	2236	21	nasal	nasal	NN
cord-022561-rv5j1201	2236	22	cavity	cavity	NN
cord-022561-rv5j1201	2236	23	with	with	IN
cord-022561-rv5j1201	2236	24	acute	acute	JJ
cord-022561-rv5j1201	2236	25	rhinitis	rhinitis	NN
cord-022561-rv5j1201	2236	26	,	,	,
cord-022561-rv5j1201	2236	27	tracheobronchial	tracheobronchial	JJ
cord-022561-rv5j1201	2236	28	lymph	lymph	NN
cord-022561-rv5j1201	2236	29	nodes	node	NNS
cord-022561-rv5j1201	2236	30	in	in	IN
cord-022561-rv5j1201	2236	31	animals	animal	NNS
cord-022561-rv5j1201	2236	32	with	with	IN
cord-022561-rv5j1201	2236	33	pneumonia	pneumonia	NN
cord-022561-rv5j1201	2237	1	(	(	-LRB-
cord-022561-rv5j1201	2237	2	Fig	Fig	NNP
cord-022561-rv5j1201	2237	3	.	.	.
cord-022561-rv5j1201	2237	4	 	 	_SP
cord-022561-rv5j1201	2237	5	13	13	CD
cord-022561-rv5j1201	2237	6	-	-	SYM
cord-022561-rv5j1201	2237	7	75	75	CD
cord-022561-rv5j1201	2237	8	)	)	-RRB-
cord-022561-rv5j1201	2237	9	,	,	,
cord-022561-rv5j1201	2237	10	and	and	CC
cord-022561-rv5j1201	2237	11	mammary	mammary	JJ
cord-022561-rv5j1201	2237	12	[	[	-LRB-
cord-022561-rv5j1201	2237	13	supramammary	supramammary	JJ
cord-022561-rv5j1201	2237	14	]	]	-RRB-
cord-022561-rv5j1201	2237	15	lymph	lymph	NN
cord-022561-rv5j1201	2237	16	nodes	node	NNS
cord-022561-rv5j1201	2237	17	in	in	IN
cord-022561-rv5j1201	2237	18	animals	animal	NNS
cord-022561-rv5j1201	2237	19	with	with	IN
cord-022561-rv5j1201	2237	20	mastitis	mastitis	NN
cord-022561-rv5j1201	2237	21	)	)	-RRB-
cord-022561-rv5j1201	2237	22	.	.	.
cord-022561-rv5j1201	2238	1	Grossly	grossly	RB
cord-022561-rv5j1201	2238	2	,	,	,
cord-022561-rv5j1201	2238	3	affected	affected	JJ
cord-022561-rv5j1201	2238	4	lymph	lymph	NN
cord-022561-rv5j1201	2238	5	nodes	node	NNS
cord-022561-rv5j1201	2238	6	in	in	IN
cord-022561-rv5j1201	2238	7	acute	acute	JJ
cord-022561-rv5j1201	2238	8	lymphadenitis	lymphadenitis	NNP
cord-022561-rv5j1201	2238	9	are	be	VBP
cord-022561-rv5j1201	2238	10	red	red	JJ
cord-022561-rv5j1201	2238	11	and	and	CC
cord-022561-rv5j1201	2238	12	edematous	edematous	JJ
cord-022561-rv5j1201	2238	13	,	,	,
cord-022561-rv5j1201	2238	14	have	have	VBP
cord-022561-rv5j1201	2238	15	taut	taut	JJ
cord-022561-rv5j1201	2238	16	capsules	capsule	NNS
cord-022561-rv5j1201	2238	17	,	,	,
cord-022561-rv5j1201	2238	18	and	and	CC
cord-022561-rv5j1201	2238	19	may	may	MD
cord-022561-rv5j1201	2238	20	have	have	VB
cord-022561-rv5j1201	2238	21	necrotic	necrotic	JJ
cord-022561-rv5j1201	2238	22	areas	area	NNS
cord-022561-rv5j1201	2238	23	(	(	-LRB-
cord-022561-rv5j1201	2238	24	Fig	Fig	NNP
cord-022561-rv5j1201	2238	25	.	.	.
cord-022561-rv5j1201	2238	26	13	13	CD
cord-022561-rv5j1201	2238	27	-	-	SYM
cord-022561-rv5j1201	2238	28	76	76	CD
cord-022561-rv5j1201	2238	29	)	)	-RRB-
cord-022561-rv5j1201	2238	30	.	.	.
cord-022561-rv5j1201	2239	1	In	in	IN
cord-022561-rv5j1201	2239	2	some	some	DT
cord-022561-rv5j1201	2239	3	instances	instance	NNS
cord-022561-rv5j1201	2239	4	the	the	DT
cord-022561-rv5j1201	2239	5	afferent	afferent	JJ
cord-022561-rv5j1201	2239	6	lymphatic	lymphatic	NN
cord-022561-rv5j1201	2239	7	vessels	vessel	NNS
cord-022561-rv5j1201	2239	8	may	may	MD
cord-022561-rv5j1201	2239	9	also	also	RB
cord-022561-rv5j1201	2239	10	be	be	VB
cord-022561-rv5j1201	2239	11	inflamed	inflame	VBN
cord-022561-rv5j1201	2239	12	(	(	-LRB-
cord-022561-rv5j1201	2239	13	lymphangitis	lymphangitis	NNP
cord-022561-rv5j1201	2239	14	)	)	-RRB-
cord-022561-rv5j1201	2239	15	.	.	.
cord-022561-rv5j1201	2240	1	The	the	DT
cord-022561-rv5j1201	2240	2	material	material	NN
cord-022561-rv5j1201	2240	3	draining	drain	VBG
cord-022561-rv5j1201	2240	4	to	to	IN
cord-022561-rv5j1201	2240	5	the	the	DT
cord-022561-rv5j1201	2240	6	regional	regional	JJ
cord-022561-rv5j1201	2240	7	lymph	lymph	NN
cord-022561-rv5j1201	2240	8	node	node	NN
cord-022561-rv5j1201	2240	9	may	may	MD
cord-022561-rv5j1201	2240	10	be	be	VB
cord-022561-rv5j1201	2240	11	microorganisms	microorganism	NNS
cord-022561-rv5j1201	2240	12	(	(	-LRB-
cord-022561-rv5j1201	2240	13	bacteria	bacteria	NNS
cord-022561-rv5j1201	2240	14	,	,	,
cord-022561-rv5j1201	2240	15	parasites	parasite	NNS
cord-022561-rv5j1201	2240	16	,	,	,
cord-022561-rv5j1201	2240	17	protozoa	protozoan	NNS
cord-022561-rv5j1201	2240	18	,	,	,
cord-022561-rv5j1201	2240	19	and	and	CC
cord-022561-rv5j1201	2240	20	fungi	fungus	NNS
cord-022561-rv5j1201	2240	21	)	)	-RRB-
cord-022561-rv5j1201	2240	22	,	,	,
cord-022561-rv5j1201	2240	23	inflammatory	inflammatory	JJ
cord-022561-rv5j1201	2240	24	mediators	mediator	NNS
cord-022561-rv5j1201	2240	25	,	,	,
cord-022561-rv5j1201	2240	26	or	or	CC
cord-022561-rv5j1201	2240	27	a	a	DT
cord-022561-rv5j1201	2240	28	sterile	sterile	JJ
cord-022561-rv5j1201	2240	29	irritant	irritant	NN
cord-022561-rv5j1201	2240	30	.	.	.
cord-022561-rv5j1201	2241	1	In	in	IN
cord-022561-rv5j1201	2241	2	septicemic	septicemic	JJ
cord-022561-rv5j1201	2241	3	diseases	disease	NNS
cord-022561-rv5j1201	2241	4	,	,	,
cord-022561-rv5j1201	2241	5	such	such	JJ
cord-022561-rv5j1201	2241	6	as	as	IN
cord-022561-rv5j1201	2241	7	bovine	bovine	JJ
cord-022561-rv5j1201	2241	8	anthrax	anthrax	NN
cord-022561-rv5j1201	2241	9	,	,	,
cord-022561-rv5j1201	2241	10	the	the	DT
cord-022561-rv5j1201	2241	11	lymph	lymph	NN
cord-022561-rv5j1201	2241	12	nodes	node	NNS
cord-022561-rv5j1201	2241	13	are	be	VBP
cord-022561-rv5j1201	2241	14	markedly	markedly	RB
cord-022561-rv5j1201	2241	15	congested	congested	JJ
cord-022561-rv5j1201	2241	16	and	and	CC
cord-022561-rv5j1201	2241	17	the	the	DT
cord-022561-rv5j1201	2241	18	sinuses	sinus	NNS
cord-022561-rv5j1201	2241	19	filled	fill	VBN
cord-022561-rv5j1201	2241	20	with	with	IN
cord-022561-rv5j1201	2241	21	blood	blood	NN
cord-022561-rv5j1201	2241	22	.	.	.
cord-022561-rv5j1201	2242	1	Examination	examination	NN
cord-022561-rv5j1201	2242	2	of	of	IN
cord-022561-rv5j1201	2242	3	these	these	DT
cord-022561-rv5j1201	2242	4	lymph	lymph	NN
cord-022561-rv5j1201	2242	5	nodes	node	NNS
cord-022561-rv5j1201	2242	6	should	should	MD
cord-022561-rv5j1201	2242	7	include	include	VB
cord-022561-rv5j1201	2242	8	culturing	culture	VBG
cord-022561-rv5j1201	2242	9	for	for	IN
cord-022561-rv5j1201	2242	10	bacteria	bacteria	NNS
cord-022561-rv5j1201	2242	11	and	and	CC
cord-022561-rv5j1201	2242	12	the	the	DT
cord-022561-rv5j1201	2242	13	examination	examination	NN
cord-022561-rv5j1201	2242	14	of	of	IN
cord-022561-rv5j1201	2242	15	smears	smear	NNS
cord-022561-rv5j1201	2242	16	and	and	CC
cord-022561-rv5j1201	2242	17	histologic	histologic	JJ
cord-022561-rv5j1201	2242	18	sections	section	NNS
cord-022561-rv5j1201	2242	19	for	for	IN
cord-022561-rv5j1201	2242	20	bacteria	bacteria	NNS
cord-022561-rv5j1201	2242	21	and	and	CC
cord-022561-rv5j1201	2242	22	fungi	fungus	NNS
cord-022561-rv5j1201	2242	23	.	.	.
cord-022561-rv5j1201	2243	1	Pyogenic	Pyogenic	NNP
cord-022561-rv5j1201	2243	2	bacteria	bacteria	NNS
cord-022561-rv5j1201	2243	3	,	,	,
cord-022561-rv5j1201	2243	4	such	such	JJ
cord-022561-rv5j1201	2243	5	as	as	IN
cord-022561-rv5j1201	2243	6	Streptococcus	Streptococcus	NNP
cord-022561-rv5j1201	2243	7	equi	equi	NN
cord-022561-rv5j1201	2243	8	ssp	ssp	NN
cord-022561-rv5j1201	2243	9	.	.	.
cord-022561-rv5j1201	2244	1	equi	equi	NN
cord-022561-rv5j1201	2244	2	in	in	IN
cord-022561-rv5j1201	2244	3	horses	horse	NNS
cord-022561-rv5j1201	2244	4	,	,	,
cord-022561-rv5j1201	2244	5	Streptococcus	Streptococcus	NNP
cord-022561-rv5j1201	2244	6	porcinus	porcinus	NN
cord-022561-rv5j1201	2244	7	in	in	IN
cord-022561-rv5j1201	2244	8	pig	pig	NN
cord-022561-rv5j1201	2244	9	,	,	,
cord-022561-rv5j1201	2244	10	and	and	CC
cord-022561-rv5j1201	2244	11	Trueperella	Trueperella	NNP
cord-022561-rv5j1201	2244	12	pyogenes	pyogene	NNS
cord-022561-rv5j1201	2244	13	in	in	IN
cord-022561-rv5j1201	2244	14	cattle	cattle	NNS
cord-022561-rv5j1201	2244	15	and	and	CC
cord-022561-rv5j1201	2244	16	sheep	sheep	NNS
cord-022561-rv5j1201	2244	17	,	,	,
cord-022561-rv5j1201	2244	18	cause	cause	VB
cord-022561-rv5j1201	2244	19	acute	acute	JJ
cord-022561-rv5j1201	2244	20	suppurative	suppurative	JJ
cord-022561-rv5j1201	2244	21	lymphadenitis	lymphadenitis	NN
cord-022561-rv5j1201	2244	22	(	(	-LRB-
cord-022561-rv5j1201	2244	23	see	see	VB
cord-022561-rv5j1201	2244	24	Disorders	disorder	NNS
cord-022561-rv5j1201	2244	25	of	of	IN
cord-022561-rv5j1201	2244	26	Horses	horse	NNS
cord-022561-rv5j1201	2244	27	and	and	CC
cord-022561-rv5j1201	2244	28	Disorders	disorder	NNS
cord-022561-rv5j1201	2244	29	of	of	IN
cord-022561-rv5j1201	2244	30	Pigs	pig	NNS
cord-022561-rv5j1201	2244	31	)	)	-RRB-
cord-022561-rv5j1201	2244	32	.	.	.
cord-022561-rv5j1201	2245	1	hereditary	hereditary	JJ
cord-022561-rv5j1201	2245	2	lymphedema	lymphedema	NN
cord-022561-rv5j1201	2245	3	has	have	VBZ
cord-022561-rv5j1201	2245	4	been	be	VBN
cord-022561-rv5j1201	2245	5	reported	report	VBN
cord-022561-rv5j1201	2245	6	in	in	IN
cord-022561-rv5j1201	2245	7	certain	certain	JJ
cord-022561-rv5j1201	2245	8	breeds	breed	NNS
cord-022561-rv5j1201	2245	9	of	of	IN
cord-022561-rv5j1201	2245	10	cattle	cattle	NNS
cord-022561-rv5j1201	2245	11	and	and	CC
cord-022561-rv5j1201	2245	12	dogs	dog	NNS
cord-022561-rv5j1201	2245	13	.	.	.
cord-022561-rv5j1201	2246	1	Grossly	grossly	RB
cord-022561-rv5j1201	2246	2	,	,	,
cord-022561-rv5j1201	2246	3	the	the	DT
cord-022561-rv5j1201	2246	4	most	most	RBS
cord-022561-rv5j1201	2246	5	severely	severely	RB
cord-022561-rv5j1201	2246	6	affected	affect	VBN
cord-022561-rv5j1201	2246	7	animals	animal	NNS
cord-022561-rv5j1201	2246	8	have	have	VBP
cord-022561-rv5j1201	2246	9	generalized	generalize	VBN
cord-022561-rv5j1201	2246	10	subcutaneous	subcutaneous	JJ
cord-022561-rv5j1201	2246	11	edema	edema	NN
cord-022561-rv5j1201	2246	12	(	(	-LRB-
cord-022561-rv5j1201	2246	13	see	see	VB
cord-022561-rv5j1201	2246	14	Fig	Fig	NNP
cord-022561-rv5j1201	2246	15	.	.	.
cord-022561-rv5j1201	2246	16	2	2	CD
cord-022561-rv5j1201	2246	17	-10	-10	CD
cord-022561-rv5j1201	2246	18	)	)	-RRB-
cord-022561-rv5j1201	2246	19	and	and	CC
cord-022561-rv5j1201	2246	20	effusions	effusion	NNS
cord-022561-rv5j1201	2246	21	.	.	.
cord-022561-rv5j1201	2247	1	In	in	IN
cord-022561-rv5j1201	2247	2	severe	severe	JJ
cord-022561-rv5j1201	2247	3	cases	case	NNS
cord-022561-rv5j1201	2247	4	the	the	DT
cord-022561-rv5j1201	2247	5	peripheral	peripheral	JJ
cord-022561-rv5j1201	2247	6	and	and	CC
cord-022561-rv5j1201	2247	7	mesenteric	mesenteric	JJ
cord-022561-rv5j1201	2247	8	lymph	lymph	NN
cord-022561-rv5j1201	2247	9	nodes	node	NNS
cord-022561-rv5j1201	2247	10	are	be	VBP
cord-022561-rv5j1201	2247	11	hypoplastic	hypoplastic	JJ
cord-022561-rv5j1201	2247	12	and	and	CC
cord-022561-rv5j1201	2247	13	characterized	characterize	VBN
cord-022561-rv5j1201	2247	14	by	by	IN
cord-022561-rv5j1201	2247	15	an	an	DT
cord-022561-rv5j1201	2247	16	absence	absence	NN
cord-022561-rv5j1201	2247	17	of	of	IN
cord-022561-rv5j1201	2247	18	follicles	follicle	NNS
cord-022561-rv5j1201	2247	19	.	.	.
cord-022561-rv5j1201	2248	1	Nodes	node	NNS
cord-022561-rv5j1201	2248	2	draining	drain	VBG
cord-022561-rv5j1201	2248	3	an	an	DT
cord-022561-rv5j1201	2248	4	edematous	edematous	JJ
cord-022561-rv5j1201	2248	5	area	area	NN
cord-022561-rv5j1201	2248	6	may	may	MD
cord-022561-rv5j1201	2248	7	be	be	VB
cord-022561-rv5j1201	2248	8	grossly	grossly	RB
cord-022561-rv5j1201	2248	9	enlarged	enlarge	VBN
cord-022561-rv5j1201	2248	10	from	from	IN
cord-022561-rv5j1201	2248	11	marked	marked	JJ
cord-022561-rv5j1201	2248	12	sinus	sinus	NN
cord-022561-rv5j1201	2248	13	edema	edema	NN
cord-022561-rv5j1201	2248	14	.	.	.
cord-022561-rv5j1201	2249	1	Lack	lack	NN
cord-022561-rv5j1201	2249	2	of	of	IN
cord-022561-rv5j1201	2249	3	Antigenic	antigenic	JJ
cord-022561-rv5j1201	2249	4	Stimulation	stimulation	NN
cord-022561-rv5j1201	2249	5	.	.	.
cord-022561-rv5j1201	2250	1	The	the	DT
cord-022561-rv5j1201	2250	2	size	size	NN
cord-022561-rv5j1201	2250	3	of	of	IN
cord-022561-rv5j1201	2250	4	the	the	DT
cord-022561-rv5j1201	2250	5	lymph	lymph	NN
cord-022561-rv5j1201	2250	6	node	node	NN
cord-022561-rv5j1201	2250	7	depends	depend	VBZ
cord-022561-rv5j1201	2250	8	on	on	IN
cord-022561-rv5j1201	2250	9	the	the	DT
cord-022561-rv5j1201	2250	10	level	level	NN
cord-022561-rv5j1201	2250	11	of	of	IN
cord-022561-rv5j1201	2250	12	phagocytosis	phagocytosis	NN
cord-022561-rv5j1201	2250	13	and	and	CC
cord-022561-rv5j1201	2250	14	antigenic	antigenic	JJ
cord-022561-rv5j1201	2250	15	stimulation	stimulation	NN
cord-022561-rv5j1201	2250	16	;	;	:
cord-022561-rv5j1201	2250	17	lymph	lymph	NN
cord-022561-rv5j1201	2250	18	nodes	node	NNS
cord-022561-rv5j1201	2250	19	that	that	WDT
cord-022561-rv5j1201	2250	20	are	be	VBP
cord-022561-rv5j1201	2250	21	not	not	RB
cord-022561-rv5j1201	2250	22	receiving	receive	VBG
cord-022561-rv5j1201	2250	23	antigenic	antigenic	JJ
cord-022561-rv5j1201	2250	24	stimuli	stimulus	NNS
cord-022561-rv5j1201	2250	25	(	(	-LRB-
cord-022561-rv5j1201	2250	26	e.g.	e.g.	RB
cord-022561-rv5j1201	2250	27	,	,	,
cord-022561-rv5j1201	2250	28	SPF	SPF	NNP
cord-022561-rv5j1201	2250	29	animals	animal	NNS
cord-022561-rv5j1201	2250	30	)	)	-RRB-
cord-022561-rv5j1201	2250	31	will	will	MD
cord-022561-rv5j1201	2250	32	be	be	VB
cord-022561-rv5j1201	2250	33	small	small	JJ
cord-022561-rv5j1201	2250	34	with	with	IN
cord-022561-rv5j1201	2250	35	low	low	JJ
cord-022561-rv5j1201	2250	36	numbers	number	NNS
cord-022561-rv5j1201	2250	37	of	of	IN
cord-022561-rv5j1201	2250	38	primary	primary	JJ
cord-022561-rv5j1201	2250	39	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	2250	40	follicles	follicle	NNS
cord-022561-rv5j1201	2250	41	and	and	CC
cord-022561-rv5j1201	2250	42	few	few	JJ
cord-022561-rv5j1201	2250	43	,	,	,
cord-022561-rv5j1201	2250	44	if	if	IN
cord-022561-rv5j1201	2250	45	any	any	DT
cord-022561-rv5j1201	2250	46	,	,	,
cord-022561-rv5j1201	2250	47	secondary	secondary	JJ
cord-022561-rv5j1201	2250	48	follicles	follicle	NNS
cord-022561-rv5j1201	2250	49	or	or	CC
cord-022561-rv5j1201	2250	50	plasma	plasma	NN
cord-022561-rv5j1201	2250	51	cells	cell	NNS
cord-022561-rv5j1201	2250	52	in	in	IN
cord-022561-rv5j1201	2250	53	the	the	DT
cord-022561-rv5j1201	2250	54	medullary	medullary	JJ
cord-022561-rv5j1201	2250	55	cords	cord	NNS
cord-022561-rv5j1201	2250	56	.	.	.
cord-022561-rv5j1201	2251	1	Conversely	conversely	RB
cord-022561-rv5j1201	2251	2	,	,	,
cord-022561-rv5j1201	2251	3	nodes	node	NNS
cord-022561-rv5j1201	2251	4	receiving	receive	VBG
cord-022561-rv5j1201	2251	5	constant	constant	JJ
cord-022561-rv5j1201	2251	6	antigenic	antigenic	JJ
cord-022561-rv5j1201	2251	7	material	material	NN
cord-022561-rv5j1201	2251	8	(	(	-LRB-
cord-022561-rv5j1201	2251	9	such	such	JJ
cord-022561-rv5j1201	2251	10	as	as	IN
cord-022561-rv5j1201	2251	11	those	those	DT
cord-022561-rv5j1201	2251	12	draining	drain	VBG
cord-022561-rv5j1201	2251	13	the	the	DT
cord-022561-rv5j1201	2251	14	oral	oral	JJ
cord-022561-rv5j1201	2251	15	cavity	cavity	NN
cord-022561-rv5j1201	2251	16	or	or	CC
cord-022561-rv5j1201	2251	17	intestines	intestine	NNS
cord-022561-rv5j1201	2251	18	)	)	-RRB-
cord-022561-rv5j1201	2251	19	are	be	VBP
cord-022561-rv5j1201	2251	20	large	large	JJ
cord-022561-rv5j1201	2251	21	with	with	IN
cord-022561-rv5j1201	2251	22	active	active	JJ
cord-022561-rv5j1201	2251	23	secondary	secondary	JJ
cord-022561-rv5j1201	2251	24	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	2251	25	follicles	follicle	NNS
cord-022561-rv5j1201	2251	26	.	.	.
cord-022561-rv5j1201	2252	1	The	the	DT
cord-022561-rv5j1201	2252	2	number	number	NN
cord-022561-rv5j1201	2252	3	of	of	IN
cord-022561-rv5j1201	2252	4	follicles	follicle	NNS
cord-022561-rv5j1201	2252	5	increases	increase	NNS
cord-022561-rv5j1201	2252	6	or	or	CC
cord-022561-rv5j1201	2252	7	decreases	decrease	VBZ
cord-022561-rv5j1201	2252	8	with	with	IN
cord-022561-rv5j1201	2252	9	changes	change	NNS
cord-022561-rv5j1201	2252	10	in	in	IN
cord-022561-rv5j1201	2252	11	the	the	DT
cord-022561-rv5j1201	2252	12	intensity	intensity	NN
cord-022561-rv5j1201	2252	13	of	of	IN
cord-022561-rv5j1201	2252	14	the	the	DT
cord-022561-rv5j1201	2252	15	antigenic	antigenic	JJ
cord-022561-rv5j1201	2252	16	stimuli	stimulus	NNS
cord-022561-rv5j1201	2252	17	,	,	,
cord-022561-rv5j1201	2252	18	and	and	CC
cord-022561-rv5j1201	2252	19	the	the	DT
cord-022561-rv5j1201	2252	20	germinal	germinal	JJ
cord-022561-rv5j1201	2252	21	centers	center	NNS
cord-022561-rv5j1201	2252	22	go	go	VBP
cord-022561-rv5j1201	2252	23	through	through	IN
cord-022561-rv5j1201	2252	24	a	a	DT
cord-022561-rv5j1201	2252	25	cycle	cycle	NN
cord-022561-rv5j1201	2252	26	of	of	IN
cord-022561-rv5j1201	2252	27	activation	activation	NN
cord-022561-rv5j1201	2252	28	,	,	,
cord-022561-rv5j1201	2252	29	depletion	depletion	NN
cord-022561-rv5j1201	2252	30	,	,	,
cord-022561-rv5j1201	2252	31	and	and	CC
cord-022561-rv5j1201	2252	32	rest	rest	NN
cord-022561-rv5j1201	2252	33	,	,	,
cord-022561-rv5j1201	2252	34	as	as	IN
cord-022561-rv5j1201	2252	35	described	describe	VBN
cord-022561-rv5j1201	2252	36	previously	previously	RB
cord-022561-rv5j1201	2252	37	(	(	-LRB-
cord-022561-rv5j1201	2252	38	see	see	VB
cord-022561-rv5j1201	2252	39	Lymph	lymph	NN
cord-022561-rv5j1201	2252	40	Nodes	node	NNS
cord-022561-rv5j1201	2252	41	,	,	,
cord-022561-rv5j1201	2252	42	Function	function	NN
cord-022561-rv5j1201	2252	43	)	)	-RRB-
cord-022561-rv5j1201	2252	44	.	.	.
cord-022561-rv5j1201	2253	1	As	as	IN
cord-022561-rv5j1201	2253	2	the	the	DT
cord-022561-rv5j1201	2253	3	antigenic	antigenic	JJ
cord-022561-rv5j1201	2253	4	response	response	NN
cord-022561-rv5j1201	2253	5	wanes	wane	VBZ
cord-022561-rv5j1201	2253	6	,	,	,
cord-022561-rv5j1201	2253	7	germinal	germinal	JJ
cord-022561-rv5j1201	2253	8	centers	center	NNS
cord-022561-rv5j1201	2253	9	become	become	VBP
cord-022561-rv5j1201	2253	10	depleted	deplete	VBN
cord-022561-rv5j1201	2253	11	of	of	IN
cord-022561-rv5j1201	2253	12	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	2253	13	,	,	,
cord-022561-rv5j1201	2253	14	and	and	CC
cord-022561-rv5j1201	2253	15	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	2253	16	follicles	follicle	NNS
cord-022561-rv5j1201	2253	17	become	become	VBP
cord-022561-rv5j1201	2253	18	smaller	small	JJR
cord-022561-rv5j1201	2253	19	.	.	.
cord-022561-rv5j1201	2254	1	Viral	Viral	NNP
cord-022561-rv5j1201	2254	2	Infections	infection	NNS
cord-022561-rv5j1201	2254	3	.	.	.
cord-022561-rv5j1201	2255	1	Many	many	JJ
cord-022561-rv5j1201	2255	2	viral	viral	JJ
cord-022561-rv5j1201	2255	3	infections	infection	NNS
cord-022561-rv5j1201	2255	4	of	of	IN
cord-022561-rv5j1201	2255	5	animals	animal	NNS
cord-022561-rv5j1201	2255	6	target	target	VBP
cord-022561-rv5j1201	2255	7	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	2255	8	and	and	CC
cord-022561-rv5j1201	2255	9	cause	cause	VB
cord-022561-rv5j1201	2255	10	the	the	DT
cord-022561-rv5j1201	2255	11	destruction	destruction	NN
cord-022561-rv5j1201	2255	12	of	of	IN
cord-022561-rv5j1201	2255	13	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	2255	14	tissue	tissue	NN
cord-022561-rv5j1201	2255	15	.	.	.
cord-022561-rv5j1201	2256	1	Of	of	IN
cord-022561-rv5j1201	2256	2	infectious	infectious	JJ
cord-022561-rv5j1201	2256	3	agents	agent	NNS
cord-022561-rv5j1201	2256	4	,	,	,
cord-022561-rv5j1201	2256	5	viruses	virus	NNS
cord-022561-rv5j1201	2256	6	most	most	RBS
cord-022561-rv5j1201	2256	7	commonly	commonly	RB
cord-022561-rv5j1201	2256	8	infect	infect	VBP
cord-022561-rv5j1201	2256	9	and	and	CC
cord-022561-rv5j1201	2256	10	injure	injure	VB
cord-022561-rv5j1201	2256	11	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	2256	12	tissues	tissue	NNS
cord-022561-rv5j1201	2256	13	and	and	CC
cord-022561-rv5j1201	2256	14	include	include	VBP
cord-022561-rv5j1201	2256	15	the	the	DT
cord-022561-rv5j1201	2256	16	following	follow	VBG
cord-022561-rv5j1201	2256	17	:	:	:
cord-022561-rv5j1201	2256	18	EHV-1	EHV-1	NNPS
cord-022561-rv5j1201	2256	19	in	in	IN
cord-022561-rv5j1201	2256	20	aborted	aborted	JJ
cord-022561-rv5j1201	2256	21	foals	foal	NNS
cord-022561-rv5j1201	2256	22	,	,	,
cord-022561-rv5j1201	2256	23	classic	classic	JJ
cord-022561-rv5j1201	2256	24	swine	swine	NN
cord-022561-rv5j1201	2256	25	fever	fever	NN
cord-022561-rv5j1201	2256	26	virus	virus	NN
cord-022561-rv5j1201	2256	27	,	,	,
cord-022561-rv5j1201	2256	28	BVDV	BVDV	NNP
cord-022561-rv5j1201	2256	29	,	,	,
cord-022561-rv5j1201	2256	30	canine	canine	JJ
cord-022561-rv5j1201	2256	31	distemper	distemper	NN
cord-022561-rv5j1201	2256	32	virus	virus	NN
cord-022561-rv5j1201	2256	33	,	,	,
cord-022561-rv5j1201	2256	34	and	and	CC
cord-022561-rv5j1201	2256	35	canine	canine	JJ
cord-022561-rv5j1201	2256	36	and	and	CC
cord-022561-rv5j1201	2256	37	feline	feline	JJ
cord-022561-rv5j1201	2256	38	parvovirus	parvovirus	NN
cord-022561-rv5j1201	2256	39	.	.	.
cord-022561-rv5j1201	2257	1	Although	although	IN
cord-022561-rv5j1201	2257	2	some	some	DT
cord-022561-rv5j1201	2257	3	viruses	virus	NNS
cord-022561-rv5j1201	2257	4	destroy	destroy	VBP
cord-022561-rv5j1201	2257	5	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	2257	6	tissue	tissue	NN
cord-022561-rv5j1201	2257	7	,	,	,
cord-022561-rv5j1201	2257	8	others	other	NNS
cord-022561-rv5j1201	2257	9	can	can	MD
cord-022561-rv5j1201	2257	10	lead	lead	VB
cord-022561-rv5j1201	2257	11	to	to	IN
cord-022561-rv5j1201	2257	12	lymph	lymph	NN
cord-022561-rv5j1201	2257	13	node	node	NN
cord-022561-rv5j1201	2257	14	hyperplasia	hyperplasia	NN
cord-022561-rv5j1201	2257	15	(	(	-LRB-
cord-022561-rv5j1201	2257	16	e.g.	e.g.	RB
cord-022561-rv5j1201	2257	17	,	,	,
cord-022561-rv5j1201	2257	18	follicular	follicular	JJ
cord-022561-rv5j1201	2257	19	B	b	NN
cord-022561-rv5j1201	2257	20	lymphocyte	lymphocyte	NN
cord-022561-rv5j1201	2257	21	hyperplasia	hyperplasia	NN
cord-022561-rv5j1201	2257	22	in	in	IN
cord-022561-rv5j1201	2257	23	FIV	FIV	NNP
cord-022561-rv5j1201	2257	24	and	and	CC
cord-022561-rv5j1201	2257	25	paracortical	paracortical	JJ
cord-022561-rv5j1201	2257	26	T	t	NN
cord-022561-rv5j1201	2257	27	lymphocyte	lymphocyte	NN
cord-022561-rv5j1201	2257	28	hyperplasia	hyperplasia	NN
cord-022561-rv5j1201	2257	29	in	in	IN
cord-022561-rv5j1201	2257	30	malignant	malignant	JJ
cord-022561-rv5j1201	2257	31	catarrhal	catarrhal	NN
cord-022561-rv5j1201	2257	32	fever	fever	NN
cord-022561-rv5j1201	2257	33	virus	virus	NN
cord-022561-rv5j1201	2257	34	)	)	-RRB-
cord-022561-rv5j1201	2257	35	or	or	CC
cord-022561-rv5j1201	2257	36	cause	cause	VB
cord-022561-rv5j1201	2257	37	neoplasia	neoplasia	NN
cord-022561-rv5j1201	2257	38	(	(	-LRB-
cord-022561-rv5j1201	2257	39	e.g.	e.g.	RB
cord-022561-rv5j1201	2257	40	,	,	,
cord-022561-rv5j1201	2257	41	FeLV	FeLV	NNP
cord-022561-rv5j1201	2257	42	,	,	,
cord-022561-rv5j1201	2257	43	BLV	BLV	NNP
cord-022561-rv5j1201	2257	44	,	,	,
cord-022561-rv5j1201	2257	45	and	and	CC
cord-022561-rv5j1201	2257	46	Marek	Marek	NNP
cord-022561-rv5j1201	2257	47	's	's	POS
cord-022561-rv5j1201	2257	48	disease	disease	NN
cord-022561-rv5j1201	2257	49	)	)	-RRB-
cord-022561-rv5j1201	2257	50	.	.	.
cord-022561-rv5j1201	2258	1	Cachexia	cachexia	NN
cord-022561-rv5j1201	2258	2	and	and	CC
cord-022561-rv5j1201	2258	3	Malnutrition	malnutrition	NN
cord-022561-rv5j1201	2258	4	.	.	.
cord-022561-rv5j1201	2259	1	Malnutrition	malnutrition	NN
cord-022561-rv5j1201	2259	2	and	and	CC
cord-022561-rv5j1201	2259	3	cachexia	cachexia	NN
cord-022561-rv5j1201	2259	4	,	,	,
cord-022561-rv5j1201	2259	5	which	which	WDT
cord-022561-rv5j1201	2259	6	occur	occur	VBP
cord-022561-rv5j1201	2259	7	with	with	IN
cord-022561-rv5j1201	2259	8	cancer	cancer	NN
cord-022561-rv5j1201	2259	9	,	,	,
cord-022561-rv5j1201	2259	10	lead	lead	VBP
cord-022561-rv5j1201	2259	11	to	to	IN
cord-022561-rv5j1201	2259	12	secondary	secondary	JJ
cord-022561-rv5j1201	2259	13	immunosuppression	immunosuppression	NN
cord-022561-rv5j1201	2259	14	through	through	IN
cord-022561-rv5j1201	2259	15	several	several	JJ
cord-022561-rv5j1201	2259	16	complex	complex	JJ
cord-022561-rv5j1201	2259	17	metabolic	metabolic	JJ
cord-022561-rv5j1201	2259	18	and	and	CC
cord-022561-rv5j1201	2259	19	neurohormonal	neurohormonal	JJ
cord-022561-rv5j1201	2259	20	aberrations	aberration	NNS
cord-022561-rv5j1201	2259	21	.	.	.
cord-022561-rv5j1201	2260	1	Starvation	starvation	NN
cord-022561-rv5j1201	2260	2	has	have	VBZ
cord-022561-rv5j1201	2260	3	marked	mark	VBN
cord-022561-rv5j1201	2260	4	effect	effect	NN
cord-022561-rv5j1201	2260	5	on	on	IN
cord-022561-rv5j1201	2260	6	the	the	DT
cord-022561-rv5j1201	2260	7	thymus	thymus	NN
cord-022561-rv5j1201	2260	8	with	with	IN
cord-022561-rv5j1201	2260	9	resultant	resultant	JJ
cord-022561-rv5j1201	2260	10	atrophy	atrophy	NN
cord-022561-rv5j1201	2260	11	of	of	IN
cord-022561-rv5j1201	2260	12	the	the	DT
cord-022561-rv5j1201	2260	13	T	T	NNP
cord-022561-rv5j1201	2260	14	lymphocyte	lymphocyte	NN
cord-022561-rv5j1201	2260	15	areas	area	NNS
cord-022561-rv5j1201	2260	16	in	in	IN
cord-022561-rv5j1201	2260	17	the	the	DT
cord-022561-rv5j1201	2260	18	spleen	spleen	NN
cord-022561-rv5j1201	2260	19	and	and	CC
cord-022561-rv5j1201	2260	20	lymph	lymph	NN
cord-022561-rv5j1201	2260	21	nodes	node	NNS
cord-022561-rv5j1201	2260	22	and	and	CC
cord-022561-rv5j1201	2260	23	may	may	MD
cord-022561-rv5j1201	2260	24	also	also	RB
cord-022561-rv5j1201	2260	25	affect	affect	VB
cord-022561-rv5j1201	2260	26	B	B	NNP
cord-022561-rv5j1201	2260	27	lymphocyte	lymphocyte	NN
cord-022561-rv5j1201	2260	28	development	development	NN
cord-022561-rv5j1201	2260	29	.	.	.
cord-022561-rv5j1201	2261	1	Lymphoid	lymphoid	JJ
cord-022561-rv5j1201	2261	2	atrophy	atrophy	NN
cord-022561-rv5j1201	2261	3	may	may	MD
cord-022561-rv5j1201	2261	4	result	result	VB
cord-022561-rv5j1201	2261	5	from	from	IN
cord-022561-rv5j1201	2261	6	physiologic	physiologic	JJ
cord-022561-rv5j1201	2261	7	and	and	CC
cord-022561-rv5j1201	2261	8	emotional	emotional	JJ
cord-022561-rv5j1201	2261	9	stress	stress	NN
cord-022561-rv5j1201	2261	10	and	and	CC
cord-022561-rv5j1201	2261	11	the	the	DT
cord-022561-rv5j1201	2261	12	concurrent	concurrent	JJ
cord-022561-rv5j1201	2261	13	release	release	NN
cord-022561-rv5j1201	2261	14	of	of	IN
cord-022561-rv5j1201	2261	15	catecholamines	catecholamine	NNS
cord-022561-rv5j1201	2261	16	and	and	CC
cord-022561-rv5j1201	2261	17	glucocorticoids	glucocorticoid	NNS
cord-022561-rv5j1201	2261	18	.	.	.
cord-022561-rv5j1201	2262	1	Glucocorticoids	Glucocorticoids	NNP
cord-022561-rv5j1201	2262	2	reduce	reduce	VBP
cord-022561-rv5j1201	2262	3	B	b	NN
cord-022561-rv5j1201	2262	4	and	and	CC
cord-022561-rv5j1201	2262	5	T	t	NN
cord-022561-rv5j1201	2262	6	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	2262	7	via	via	IN
cord-022561-rv5j1201	2262	8	redistribution	redistribution	NN
cord-022561-rv5j1201	2262	9	of	of	IN
cord-022561-rv5j1201	2262	10	these	these	DT
cord-022561-rv5j1201	2262	11	cells	cell	NNS
cord-022561-rv5j1201	2262	12	and	and	CC
cord-022561-rv5j1201	2262	13	glucocorticoidinduced	glucocorticoidinduce	VBN
cord-022561-rv5j1201	2262	14	apoptosis	apoptosis	NN
cord-022561-rv5j1201	2262	15	.	.	.
cord-022561-rv5j1201	2263	1	T	T	NNP
cord-022561-rv5j1201	2263	2	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	2263	3	are	be	VBP
cord-022561-rv5j1201	2263	4	more	more	RBR
cord-022561-rv5j1201	2263	5	sensitive	sensitive	JJ
cord-022561-rv5j1201	2263	6	to	to	IN
cord-022561-rv5j1201	2263	7	glucocorticoid	glucocorticoid	NN
cord-022561-rv5j1201	2263	8	-	-	HYPH
cord-022561-rv5j1201	2263	9	induced	induce	VBN
cord-022561-rv5j1201	2263	10	apoptosis	apoptosis	NN
cord-022561-rv5j1201	2263	11	than	than	IN
cord-022561-rv5j1201	2263	12	are	be	VBP
cord-022561-rv5j1201	2263	13	B	b	NN
cord-022561-rv5j1201	2263	14	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	2263	15	.	.	.
cord-022561-rv5j1201	2264	1	Aging	age	VBG
cord-022561-rv5j1201	2264	2	.	.	.
cord-022561-rv5j1201	2265	1	As	as	IN
cord-022561-rv5j1201	2265	2	part	part	NN
cord-022561-rv5j1201	2265	3	of	of	IN
cord-022561-rv5j1201	2265	4	the	the	DT
cord-022561-rv5j1201	2265	5	general	general	JJ
cord-022561-rv5j1201	2265	6	aging	age	VBG
cord-022561-rv5j1201	2265	7	change	change	NN
cord-022561-rv5j1201	2265	8	of	of	IN
cord-022561-rv5j1201	2265	9	cells	cell	NNS
cord-022561-rv5j1201	2265	10	as	as	IN
cord-022561-rv5j1201	2265	11	the	the	DT
cord-022561-rv5j1201	2265	12	body	body	NN
cord-022561-rv5j1201	2265	13	ages	age	NNS
cord-022561-rv5j1201	2265	14	,	,	,
cord-022561-rv5j1201	2265	15	there	there	EX
cord-022561-rv5j1201	2265	16	is	be	VBZ
cord-022561-rv5j1201	2265	17	reduction	reduction	NN
cord-022561-rv5j1201	2265	18	in	in	IN
cord-022561-rv5j1201	2265	19	the	the	DT
cord-022561-rv5j1201	2265	20	number	number	NN
cord-022561-rv5j1201	2265	21	of	of	IN
cord-022561-rv5j1201	2265	22	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	2265	23	produced	produce	VBN
cord-022561-rv5j1201	2265	24	by	by	IN
cord-022561-rv5j1201	2265	25	the	the	DT
cord-022561-rv5j1201	2265	26	bone	bone	NN
cord-022561-rv5j1201	2265	27	marrow	marrow	NN
cord-022561-rv5j1201	2265	28	and	and	CC
cord-022561-rv5j1201	2265	29	regressed	regress	VBN
cord-022561-rv5j1201	2265	30	thymus	thymus	NN
cord-022561-rv5j1201	2265	31	,	,	,
cord-022561-rv5j1201	2265	32	and	and	CC
cord-022561-rv5j1201	2265	33	consequently	consequently	RB
cord-022561-rv5j1201	2265	34	a	a	DT
cord-022561-rv5j1201	2265	35	reduction	reduction	NN
cord-022561-rv5j1201	2265	36	in	in	IN
cord-022561-rv5j1201	2265	37	the	the	DT
cord-022561-rv5j1201	2265	38	B	b	NN
cord-022561-rv5j1201	2265	39	and	and	CC
cord-022561-rv5j1201	2265	40	T	t	NN
cord-022561-rv5j1201	2265	41	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	2265	42	in	in	IN
cord-022561-rv5j1201	2265	43	secondary	secondary	JJ
cord-022561-rv5j1201	2265	44	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	2265	45	organs	organ	NNS
cord-022561-rv5j1201	2265	46	,	,	,
cord-022561-rv5j1201	2265	47	resulting	result	VBG
cord-022561-rv5j1201	2265	48	in	in	IN
cord-022561-rv5j1201	2265	49	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	2265	50	atrophy	atrophy	NN
cord-022561-rv5j1201	2265	51	.	.	.
cord-022561-rv5j1201	2266	1	Consequently	consequently	RB
cord-022561-rv5j1201	2266	2	,	,	,
cord-022561-rv5j1201	2266	3	lymph	lymph	NN
cord-022561-rv5j1201	2266	4	nodes	node	NNS
cord-022561-rv5j1201	2266	5	are	be	VBP
cord-022561-rv5j1201	2266	6	small	small	JJ
cord-022561-rv5j1201	2266	7	,	,	,
cord-022561-rv5j1201	2266	8	with	with	IN
cord-022561-rv5j1201	2266	9	loss	loss	NN
cord-022561-rv5j1201	2266	10	of	of	IN
cord-022561-rv5j1201	2266	11	B	b	NN
cord-022561-rv5j1201	2266	12	and	and	CC
cord-022561-rv5j1201	2266	13	T	t	NN
cord-022561-rv5j1201	2266	14	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	2266	15	and	and	CC
cord-022561-rv5j1201	2266	16	plasma	plasma	NN
cord-022561-rv5j1201	2266	17	cells	cell	NNS
cord-022561-rv5j1201	2266	18	in	in	IN
cord-022561-rv5j1201	2266	19	the	the	DT
cord-022561-rv5j1201	2266	20	cortical	cortical	JJ
cord-022561-rv5j1201	2266	21	follicles	follicle	NNS
cord-022561-rv5j1201	2266	22	,	,	,
cord-022561-rv5j1201	2266	23	paracortex	paracortex	NN
cord-022561-rv5j1201	2266	24	,	,	,
cord-022561-rv5j1201	2266	25	and	and	CC
cord-022561-rv5j1201	2266	26	medullary	medullary	JJ
cord-022561-rv5j1201	2266	27	cords	cord	NNS
cord-022561-rv5j1201	2266	28	,	,	,
cord-022561-rv5j1201	2266	29	respectively	respectively	RB
cord-022561-rv5j1201	2266	30	.	.	.
cord-022561-rv5j1201	2267	1	Radiation	radiation	NN
cord-022561-rv5j1201	2267	2	.	.	.
cord-022561-rv5j1201	2268	1	Local	local	JJ
cord-022561-rv5j1201	2268	2	or	or	CC
cord-022561-rv5j1201	2268	3	palliative	palliative	JJ
cord-022561-rv5j1201	2268	4	treatment	treatment	NN
cord-022561-rv5j1201	2268	5	of	of	IN
cord-022561-rv5j1201	2268	6	cancer	cancer	NN
cord-022561-rv5j1201	2268	7	may	may	MD
cord-022561-rv5j1201	2268	8	include	include	VB
cord-022561-rv5j1201	2268	9	radiotherapy	radiotherapy	NN
cord-022561-rv5j1201	2268	10	(	(	-LRB-
cord-022561-rv5j1201	2268	11	ionizing	ionize	VBG
cord-022561-rv5j1201	2268	12	radiation	radiation	NN
cord-022561-rv5j1201	2268	13	)	)	-RRB-
cord-022561-rv5j1201	2268	14	to	to	TO
cord-022561-rv5j1201	2268	15	target	target	VB
cord-022561-rv5j1201	2268	16	and	and	CC
cord-022561-rv5j1201	2268	17	damage	damage	VB
cord-022561-rv5j1201	2268	18	the	the	DT
cord-022561-rv5j1201	2268	19	DNA	dna	NN
cord-022561-rv5j1201	2268	20	of	of	IN
cord-022561-rv5j1201	2268	21	the	the	DT
cord-022561-rv5j1201	2268	22	neoplastic	neoplastic	JJ
cord-022561-rv5j1201	2268	23	cells	cell	NNS
cord-022561-rv5j1201	2268	24	.	.	.
cord-022561-rv5j1201	2269	1	Although	although	IN
cord-022561-rv5j1201	2269	2	some	some	DT
cord-022561-rv5j1201	2269	3	immunosuppression	immunosuppression	NN
cord-022561-rv5j1201	2269	4	may	may	MD
cord-022561-rv5j1201	2269	5	be	be	VB
cord-022561-rv5j1201	2269	6	noted	note	VBN
cord-022561-rv5j1201	2269	7	,	,	,
cord-022561-rv5j1201	2269	8	particularly	particularly	RB
cord-022561-rv5j1201	2269	9	if	if	IN
cord-022561-rv5j1201	2269	10	bone	bone	NN
cord-022561-rv5j1201	2269	11	marrow	marrow	NN
cord-022561-rv5j1201	2269	12	or	or	CC
cord-022561-rv5j1201	2269	13	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	2269	14	tissues	tissue	NNS
cord-022561-rv5j1201	2269	15	are	be	VBP
cord-022561-rv5j1201	2269	16	within	within	IN
cord-022561-rv5j1201	2269	17	the	the	DT
cord-022561-rv5j1201	2269	18	irradiated	irradiate	VBN
cord-022561-rv5j1201	2269	19	field	field	NN
cord-022561-rv5j1201	2269	20	,	,	,
cord-022561-rv5j1201	2269	21	mounting	mount	VBG
cord-022561-rv5j1201	2269	22	evidence	evidence	NN
cord-022561-rv5j1201	2269	23	suggests	suggest	VBZ
cord-022561-rv5j1201	2269	24	that	that	IN
cord-022561-rv5j1201	2269	25	radiotherapy	radiotherapy	NN
cord-022561-rv5j1201	2269	26	can	can	MD
cord-022561-rv5j1201	2269	27	induce	induce	VB
cord-022561-rv5j1201	2269	28	a	a	DT
cord-022561-rv5j1201	2269	29	cascade	cascade	NN
cord-022561-rv5j1201	2269	30	of	of	IN
cord-022561-rv5j1201	2269	31	proimmunogenic	proimmunogenic	NN
cord-022561-rv5j1201	2269	32	effects	effect	NNS
cord-022561-rv5j1201	2269	33	that	that	WDT
cord-022561-rv5j1201	2269	34	engage	engage	VBP
cord-022561-rv5j1201	2269	35	the	the	DT
cord-022561-rv5j1201	2269	36	innate	innate	JJ
cord-022561-rv5j1201	2269	37	and	and	CC
cord-022561-rv5j1201	2269	38	adaptive	adaptive	JJ
cord-022561-rv5j1201	2269	39	immune	immune	JJ
cord-022561-rv5j1201	2269	40	systems	system	NNS
cord-022561-rv5j1201	2269	41	to	to	TO
cord-022561-rv5j1201	2269	42	contribute	contribute	VB
cord-022561-rv5j1201	2269	43	to	to	IN
cord-022561-rv5j1201	2269	44	the	the	DT
cord-022561-rv5j1201	2269	45	destruction	destruction	NN
cord-022561-rv5j1201	2269	46	of	of	IN
cord-022561-rv5j1201	2269	47	tumor	tumor	NN
cord-022561-rv5j1201	2269	48	cells	cell	NNS
cord-022561-rv5j1201	2269	49	.	.	.
cord-022561-rv5j1201	2270	1	Fibrosis	fibrosis	NN
cord-022561-rv5j1201	2270	2	of	of	IN
cord-022561-rv5j1201	2270	3	tissues	tissue	NNS
cord-022561-rv5j1201	2270	4	within	within	IN
cord-022561-rv5j1201	2270	5	the	the	DT
cord-022561-rv5j1201	2270	6	irradiated	irradiate	VBN
cord-022561-rv5j1201	2270	7	field	field	NN
cord-022561-rv5j1201	2270	8	also	also	RB
cord-022561-rv5j1201	2270	9	occurs	occur	VBZ
cord-022561-rv5j1201	2270	10	as	as	IN
cord-022561-rv5j1201	2270	11	mainly	mainly	RB
cord-022561-rv5j1201	2270	12	a	a	DT
cord-022561-rv5j1201	2270	13	late	late	JJ
cord-022561-rv5j1201	2270	14	effect	effect	NN
cord-022561-rv5j1201	2270	15	of	of	IN
cord-022561-rv5j1201	2270	16	chronic	chronic	JJ
cord-022561-rv5j1201	2270	17	radiation	radiation	NN
cord-022561-rv5j1201	2270	18	.	.	.
cord-022561-rv5j1201	2271	1	bouts	bout	NNS
cord-022561-rv5j1201	2271	2	of	of	IN
cord-022561-rv5j1201	2271	3	chronic	chronic	JJ
cord-022561-rv5j1201	2271	4	lymphadenitis	lymphadenitis	NN
cord-022561-rv5j1201	2271	5	(	(	-LRB-
cord-022561-rv5j1201	2271	6	e.g.	e.g.	RB
cord-022561-rv5j1201	2271	7	,	,	,
cord-022561-rv5j1201	2271	8	regional	regional	JJ
cord-022561-rv5j1201	2271	9	lymph	lymph	NN
cord-022561-rv5j1201	2271	10	node	node	NN
cord-022561-rv5j1201	2271	11	draining	drain	VBG
cord-022561-rv5j1201	2271	12	chronic	chronic	JJ
cord-022561-rv5j1201	2271	13	mastitis	mastitis	NN
cord-022561-rv5j1201	2271	14	in	in	IN
cord-022561-rv5j1201	2271	15	cows	cow	NNS
cord-022561-rv5j1201	2271	16	)	)	-RRB-
cord-022561-rv5j1201	2271	17	lead	lead	VBP
cord-022561-rv5j1201	2271	18	to	to	IN
cord-022561-rv5j1201	2271	19	fibrosis	fibrosis	NN
cord-022561-rv5j1201	2271	20	and	and	CC
cord-022561-rv5j1201	2271	21	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	2271	22	hyperplasia	hyperplasia	NN
cord-022561-rv5j1201	2271	23	,	,	,
cord-022561-rv5j1201	2271	24	in	in	IN
cord-022561-rv5j1201	2271	25	addition	addition	NN
cord-022561-rv5j1201	2271	26	to	to	IN
cord-022561-rv5j1201	2271	27	chronic	chronic	JJ
cord-022561-rv5j1201	2271	28	abscesses	abscess	NNS
cord-022561-rv5j1201	2271	29	.	.	.
cord-022561-rv5j1201	2272	1	The	the	DT
cord-022561-rv5j1201	2272	2	classic	classic	JJ
cord-022561-rv5j1201	2272	3	example	example	NN
cord-022561-rv5j1201	2272	4	of	of	IN
cord-022561-rv5j1201	2272	5	chronic	chronic	JJ
cord-022561-rv5j1201	2272	6	suppurative	suppurative	JJ
cord-022561-rv5j1201	2272	7	lymphadenitis	lymphadenitis	NN
cord-022561-rv5j1201	2272	8	with	with	IN
cord-022561-rv5j1201	2272	9	encapsulated	encapsulate	VBN
cord-022561-rv5j1201	2272	10	abscesses	abscess	NNS
cord-022561-rv5j1201	2272	11	is	be	VBZ
cord-022561-rv5j1201	2272	12	caseous	caseous	JJ
cord-022561-rv5j1201	2272	13	lymphadenitis	lymphadenitis	NNP
cord-022561-rv5j1201	2272	14	,	,	,
cord-022561-rv5j1201	2272	15	a	a	DT
cord-022561-rv5j1201	2272	16	disease	disease	NN
cord-022561-rv5j1201	2272	17	of	of	IN
cord-022561-rv5j1201	2272	18	sheep	sheep	NNS
cord-022561-rv5j1201	2272	19	and	and	CC
cord-022561-rv5j1201	2272	20	goats	goat	NNS
cord-022561-rv5j1201	2272	21	caused	cause	VBN
cord-022561-rv5j1201	2272	22	by	by	IN
cord-022561-rv5j1201	2272	23	C.	C.	NNP
cord-022561-rv5j1201	2272	24	(	(	-LRB-
cord-022561-rv5j1201	2272	25	also	also	RB
cord-022561-rv5j1201	2272	26	see	see	VBP
cord-022561-rv5j1201	2272	27	Disorders	disorder	NNS
cord-022561-rv5j1201	2272	28	of	of	IN
cord-022561-rv5j1201	2272	29	Ruminants	ruminant	NNS
cord-022561-rv5j1201	2272	30	)	)	-RRB-
cord-022561-rv5j1201	2272	31	.	.	.
cord-022561-rv5j1201	2273	1	It	-PRON-	PRP
cord-022561-rv5j1201	2273	2	is	be	VBZ
cord-022561-rv5j1201	2273	3	also	also	RB
cord-022561-rv5j1201	2273	4	the	the	DT
cord-022561-rv5j1201	2273	5	cause	cause	NN
cord-022561-rv5j1201	2273	6	of	of	IN
cord-022561-rv5j1201	2273	7	ulcerative	ulcerative	JJ
cord-022561-rv5j1201	2273	8	lymphangitis	lymphangitis	NN
cord-022561-rv5j1201	2273	9	in	in	IN
cord-022561-rv5j1201	2273	10	cattle	cattle	NNS
cord-022561-rv5j1201	2273	11	and	and	CC
cord-022561-rv5j1201	2273	12	horses	horse	NNS
cord-022561-rv5j1201	2273	13	and	and	CC
cord-022561-rv5j1201	2273	14	pectoral	pectoral	JJ
cord-022561-rv5j1201	2273	15	abscesses	abscess	NNS
cord-022561-rv5j1201	2273	16	in	in	IN
cord-022561-rv5j1201	2273	17	horses	horse	NNS
cord-022561-rv5j1201	2273	18	.	.	.
cord-022561-rv5j1201	2274	1	Classic	classic	JJ
cord-022561-rv5j1201	2274	2	examples	example	NNS
cord-022561-rv5j1201	2274	3	of	of	IN
cord-022561-rv5j1201	2274	4	focal	focal	JJ
cord-022561-rv5j1201	2274	5	to	to	IN
cord-022561-rv5j1201	2274	6	multifocal	multifocal	JJ
cord-022561-rv5j1201	2274	7	granulomatous	granulomatous	JJ
cord-022561-rv5j1201	2274	8	lymphadenitis	lymphadenitis	NN
cord-022561-rv5j1201	2274	9	are	be	VBP
cord-022561-rv5j1201	2274	10	Mycobacterium	Mycobacterium	NNP
cord-022561-rv5j1201	2274	11	tuberculosis	tuberculosis	NN
cord-022561-rv5j1201	2274	12	complex	complex	NN
cord-022561-rv5j1201	2274	13	,	,	,
cord-022561-rv5j1201	2274	14	which	which	WDT
cord-022561-rv5j1201	2274	15	includes	include	VBZ
cord-022561-rv5j1201	2274	16	M.	M.	NNP
cord-022561-rv5j1201	2274	17	bovis	bovis	NN
cord-022561-rv5j1201	2274	18	among	among	IN
cord-022561-rv5j1201	2274	19	others	other	NNS
cord-022561-rv5j1201	2274	20	.	.	.
cord-022561-rv5j1201	2275	1	Members	member	NNS
cord-022561-rv5j1201	2275	2	of	of	IN
cord-022561-rv5j1201	2275	3	M.	M.	NNP
cord-022561-rv5j1201	2275	4	avium	avium	NN
cord-022561-rv5j1201	2275	5	complex	complex	JJ
cord-022561-rv5j1201	2275	6	cause	cause	VBP
cord-022561-rv5j1201	2275	7	similar	similar	JJ
cord-022561-rv5j1201	2275	8	lesions	lesion	NNS
cord-022561-rv5j1201	2275	9	and	and	CC
cord-022561-rv5j1201	2275	10	have	have	VBP
cord-022561-rv5j1201	2275	11	been	be	VBN
cord-022561-rv5j1201	2275	12	described	describe	VBN
cord-022561-rv5j1201	2275	13	in	in	IN
cord-022561-rv5j1201	2275	14	a	a	DT
cord-022561-rv5j1201	2275	15	number	number	NN
cord-022561-rv5j1201	2275	16	of	of	IN
cord-022561-rv5j1201	2275	17	species	specie	NNS
cord-022561-rv5j1201	2275	18	,	,	,
cord-022561-rv5j1201	2275	19	including	include	VBG
cord-022561-rv5j1201	2275	20	dogs	dog	NNS
cord-022561-rv5j1201	2275	21	,	,	,
cord-022561-rv5j1201	2275	22	cats	cat	NNS
cord-022561-rv5j1201	2275	23	,	,	,
cord-022561-rv5j1201	2275	24	primates	primate	NNS
cord-022561-rv5j1201	2275	25	,	,	,
cord-022561-rv5j1201	2275	26	pigs	pig	NNS
cord-022561-rv5j1201	2275	27	,	,	,
cord-022561-rv5j1201	2275	28	cattle	cattle	NNS
cord-022561-rv5j1201	2275	29	,	,	,
cord-022561-rv5j1201	2275	30	sheep	sheep	NNS
cord-022561-rv5j1201	2275	31	,	,	,
cord-022561-rv5j1201	2275	32	horses	horse	NNS
cord-022561-rv5j1201	2275	33	,	,	,
cord-022561-rv5j1201	2275	34	and	and	CC
cord-022561-rv5j1201	2275	35	human	human	JJ
cord-022561-rv5j1201	2275	36	beings	being	NNS
cord-022561-rv5j1201	2275	37	.	.	.
cord-022561-rv5j1201	2276	1	Infection	infection	NN
cord-022561-rv5j1201	2276	2	may	may	MD
cord-022561-rv5j1201	2276	3	begin	begin	VB
cord-022561-rv5j1201	2276	4	by	by	IN
cord-022561-rv5j1201	2276	5	inhalation	inhalation	NN
cord-022561-rv5j1201	2276	6	of	of	IN
cord-022561-rv5j1201	2276	7	aerosol	aerosol	NN
cord-022561-rv5j1201	2276	8	droplets	droplet	NNS
cord-022561-rv5j1201	2276	9	containing	contain	VBG
cord-022561-rv5j1201	2276	10	the	the	DT
cord-022561-rv5j1201	2276	11	bacilli	bacilli	NN
cord-022561-rv5j1201	2276	12	,	,	,
cord-022561-rv5j1201	2276	13	which	which	WDT
cord-022561-rv5j1201	2276	14	may	may	MD
cord-022561-rv5j1201	2276	15	spread	spread	VB
cord-022561-rv5j1201	2276	16	via	via	IN
cord-022561-rv5j1201	2276	17	the	the	DT
cord-022561-rv5j1201	2276	18	lymphatic	lymphatic	JJ
cord-022561-rv5j1201	2276	19	vessels	vessel	NNS
cord-022561-rv5j1201	2276	20	to	to	IN
cord-022561-rv5j1201	2276	21	regional	regional	JJ
cord-022561-rv5j1201	2276	22	lymph	lymph	NN
cord-022561-rv5j1201	2276	23	nodes	node	NNS
cord-022561-rv5j1201	2276	24	,	,	,
cord-022561-rv5j1201	2276	25	resulting	result	VBG
cord-022561-rv5j1201	2276	26	in	in	IN
cord-022561-rv5j1201	2276	27	granulomatous	granulomatous	JJ
cord-022561-rv5j1201	2276	28	lymphangitis	lymphangitis	NNP
cord-022561-rv5j1201	2276	29	and	and	CC
cord-022561-rv5j1201	2276	30	lymphadenitis	lymphadenitis	NNP
cord-022561-rv5j1201	2276	31	(	(	-LRB-
cord-022561-rv5j1201	2276	32	Fig	Fig	NNP
cord-022561-rv5j1201	2276	33	.	.	.
cord-022561-rv5j1201	2276	34	13	13	CD
cord-022561-rv5j1201	2276	35	-	-	SYM
cord-022561-rv5j1201	2276	36	81	81	CD
cord-022561-rv5j1201	2276	37	)	)	-RRB-
cord-022561-rv5j1201	2276	38	.	.	.
cord-022561-rv5j1201	2277	1	Initially	initially	RB
cord-022561-rv5j1201	2277	2	lesions	lesion	NNS
cord-022561-rv5j1201	2277	3	in	in	IN
cord-022561-rv5j1201	2277	4	the	the	DT
cord-022561-rv5j1201	2277	5	lymphatic	lymphatic	JJ
cord-022561-rv5j1201	2277	6	system	system	NN
cord-022561-rv5j1201	2277	7	are	be	VBP
cord-022561-rv5j1201	2277	8	confined	confine	VBN
cord-022561-rv5j1201	2277	9	to	to	IN
cord-022561-rv5j1201	2277	10	the	the	DT
cord-022561-rv5j1201	2277	11	lymphatic	lymphatic	JJ
cord-022561-rv5j1201	2277	12	vessels	vessel	NNS
cord-022561-rv5j1201	2277	13	(	(	-LRB-
cord-022561-rv5j1201	2277	14	granulomatous	granulomatous	JJ
cord-022561-rv5j1201	2277	15	lymphangitis	lymphangitis	NNP
cord-022561-rv5j1201	2277	16	)	)	-RRB-
cord-022561-rv5j1201	2277	17	and	and	CC
cord-022561-rv5j1201	2277	18	regional	regional	JJ
cord-022561-rv5j1201	2277	19	lymph	lymph	NN
cord-022561-rv5j1201	2277	20	nodes	node	NNS
cord-022561-rv5j1201	2277	21	(	(	-LRB-
cord-022561-rv5j1201	2277	22	e.g.	e.g.	RB
cord-022561-rv5j1201	2277	23	,	,	,
cord-022561-rv5j1201	2277	24	the	the	DT
cord-022561-rv5j1201	2277	25	tracheobronchial	tracheobronchial	JJ
cord-022561-rv5j1201	2277	26	lymph	lymph	NN
cord-022561-rv5j1201	2277	27	nodes	node	NNS
cord-022561-rv5j1201	2277	28	in	in	IN
cord-022561-rv5j1201	2277	29	the	the	DT
cord-022561-rv5j1201	2277	30	case	case	NN
cord-022561-rv5j1201	2277	31	of	of	IN
cord-022561-rv5j1201	2277	32	pulmonary	pulmonary	NN
cord-022561-rv5j1201	2277	33	Histologically	Histologically	NNP
cord-022561-rv5j1201	2277	34	,	,	,
cord-022561-rv5j1201	2277	35	the	the	DT
cord-022561-rv5j1201	2277	36	subcapsular	subcapsular	JJ
cord-022561-rv5j1201	2277	37	,	,	,
cord-022561-rv5j1201	2277	38	trabecular	trabecular	NN
cord-022561-rv5j1201	2277	39	,	,	,
cord-022561-rv5j1201	2277	40	and	and	CC
cord-022561-rv5j1201	2277	41	medullary	medullary	JJ
cord-022561-rv5j1201	2277	42	sinuses	sinus	NNS
cord-022561-rv5j1201	2277	43	and	and	CC
cord-022561-rv5j1201	2277	44	the	the	DT
cord-022561-rv5j1201	2277	45	parenchyma	parenchyma	NN
cord-022561-rv5j1201	2277	46	of	of	IN
cord-022561-rv5j1201	2277	47	the	the	DT
cord-022561-rv5j1201	2277	48	cortex	cortex	NN
cord-022561-rv5j1201	2277	49	and	and	CC
cord-022561-rv5j1201	2277	50	medulla	medulla	NN
cord-022561-rv5j1201	2277	51	have	have	VBP
cord-022561-rv5j1201	2277	52	focal	focal	NN
cord-022561-rv5j1201	2277	53	to	to	IN
cord-022561-rv5j1201	2277	54	coalescing	coalesce	VBG
cord-022561-rv5j1201	2277	55	foci	foci	NN
cord-022561-rv5j1201	2277	56	of	of	IN
cord-022561-rv5j1201	2277	57	neutrophilic	neutrophilic	JJ
cord-022561-rv5j1201	2277	58	inflammation	inflammation	NN
cord-022561-rv5j1201	2277	59	,	,	,
cord-022561-rv5j1201	2277	60	necrosis	necrosis	NN
cord-022561-rv5j1201	2277	61	,	,	,
cord-022561-rv5j1201	2277	62	and	and	CC
cord-022561-rv5j1201	2277	63	fibrin	fibrin	NN
cord-022561-rv5j1201	2277	64	deposition	deposition	NN
cord-022561-rv5j1201	2277	65	(	(	-LRB-
cord-022561-rv5j1201	2277	66	Fig	Fig	NNP
cord-022561-rv5j1201	2277	67	.	.	.
cord-022561-rv5j1201	2277	68	13	13	CD
cord-022561-rv5j1201	2277	69	-	-	SYM
cord-022561-rv5j1201	2277	70	78	78	CD
cord-022561-rv5j1201	2277	71	)	)	-RRB-
cord-022561-rv5j1201	2277	72	.	.	.
cord-022561-rv5j1201	2278	1	If	if	IN
cord-022561-rv5j1201	2278	2	inflammation	inflammation	NN
cord-022561-rv5j1201	2278	3	in	in	IN
cord-022561-rv5j1201	2278	4	the	the	DT
cord-022561-rv5j1201	2278	5	lymph	lymph	NN
cord-022561-rv5j1201	2278	6	node	node	NN
cord-022561-rv5j1201	2278	7	continues	continue	VBZ
cord-022561-rv5j1201	2278	8	for	for	IN
cord-022561-rv5j1201	2278	9	several	several	JJ
cord-022561-rv5j1201	2278	10	days	day	NNS
cord-022561-rv5j1201	2278	11	or	or	CC
cord-022561-rv5j1201	2278	12	longer	long	JJR
cord-022561-rv5j1201	2278	13	,	,	,
cord-022561-rv5j1201	2278	14	the	the	DT
cord-022561-rv5j1201	2278	15	lymph	lymph	NN
cord-022561-rv5j1201	2278	16	node	node	NN
cord-022561-rv5j1201	2278	17	is	be	VBZ
cord-022561-rv5j1201	2278	18	further	further	RB
cord-022561-rv5j1201	2278	19	enlarged	enlarge	VBN
cord-022561-rv5j1201	2278	20	by	by	IN
cord-022561-rv5j1201	2278	21	follicular	follicular	JJ
cord-022561-rv5j1201	2278	22	hyperplasia	hyperplasia	NN
cord-022561-rv5j1201	2278	23	and	and	CC
cord-022561-rv5j1201	2278	24	plasmacytosis	plasmacytosis	NN
cord-022561-rv5j1201	2278	25	of	of	IN
cord-022561-rv5j1201	2278	26	the	the	DT
cord-022561-rv5j1201	2278	27	medullary	medullary	JJ
cord-022561-rv5j1201	2278	28	cords	cord	NNS
cord-022561-rv5j1201	2278	29	from	from	IN
cord-022561-rv5j1201	2278	30	the	the	DT
cord-022561-rv5j1201	2278	31	expected	expect	VBN
cord-022561-rv5j1201	2278	32	immune	immune	JJ
cord-022561-rv5j1201	2278	33	response	response	NN
cord-022561-rv5j1201	2278	34	.	.	.
cord-022561-rv5j1201	2279	1	Chronic	Chronic	NNP
cord-022561-rv5j1201	2279	2	Lymphadenitis	Lymphadenitis	NNP
cord-022561-rv5j1201	2279	3	.	.	.
cord-022561-rv5j1201	2280	1	The	the	DT
cord-022561-rv5j1201	2280	2	types	type	NNS
cord-022561-rv5j1201	2280	3	of	of	IN
cord-022561-rv5j1201	2280	4	chronic	chronic	JJ
cord-022561-rv5j1201	2280	5	lymphadenitis	lymphadenitis	NN
cord-022561-rv5j1201	2280	6	include	include	VBP
cord-022561-rv5j1201	2280	7	chronic	chronic	JJ
cord-022561-rv5j1201	2280	8	suppurative	suppurative	JJ
cord-022561-rv5j1201	2280	9	lymphadenitis	lymphadenitis	NN
cord-022561-rv5j1201	2280	10	,	,	,
cord-022561-rv5j1201	2280	11	diffuse	diffuse	VB
cord-022561-rv5j1201	2280	12	granulomatous	granulomatous	JJ
cord-022561-rv5j1201	2280	13	inflammation	inflammation	NN
cord-022561-rv5j1201	2280	14	,	,	,
cord-022561-rv5j1201	2280	15	and	and	CC
cord-022561-rv5j1201	2280	16	discrete	discrete	JJ
cord-022561-rv5j1201	2280	17	granulomas	granuloma	NNS
cord-022561-rv5j1201	2280	18	.	.	.
cord-022561-rv5j1201	2281	1	In	in	IN
cord-022561-rv5j1201	2281	2	chronic	chronic	JJ
cord-022561-rv5j1201	2281	3	suppurative	suppurative	JJ
cord-022561-rv5j1201	2281	4	inflammation	inflammation	NN
cord-022561-rv5j1201	2281	5	,	,	,
cord-022561-rv5j1201	2281	6	abscesses	abscess	NNS
cord-022561-rv5j1201	2281	7	range	range	VBP
cord-022561-rv5j1201	2281	8	in	in	IN
cord-022561-rv5j1201	2281	9	size	size	NN
cord-022561-rv5j1201	2281	10	from	from	IN
cord-022561-rv5j1201	2281	11	small	small	JJ
cord-022561-rv5j1201	2281	12	microabscesses	microabscesse	NNS
cord-022561-rv5j1201	2281	13	to	to	IN
cord-022561-rv5j1201	2281	14	large	large	JJ
cord-022561-rv5j1201	2281	15	abscesses	abscess	NNS
cord-022561-rv5j1201	2281	16	that	that	WDT
cord-022561-rv5j1201	2281	17	occupy	occupy	VBP
cord-022561-rv5j1201	2281	18	and	and	CC
cord-022561-rv5j1201	2281	19	obliterate	obliterate	VB
cord-022561-rv5j1201	2281	20	the	the	DT
cord-022561-rv5j1201	2281	21	whole	whole	JJ
cord-022561-rv5j1201	2281	22	node	node	NN
cord-022561-rv5j1201	2281	23	.	.	.
cord-022561-rv5j1201	2282	1	Recurrent	Recurrent	NNP
cord-022561-rv5j1201	2282	2	Figure	Figure	NNP
cord-022561-rv5j1201	2282	3	13	13	CD
cord-022561-rv5j1201	2282	4	-76	-76	CD
cord-022561-rv5j1201	2282	5	Acute	Acute	NNP
cord-022561-rv5j1201	2282	6	Lymphadenitis	Lymphadenitis	NNP
cord-022561-rv5j1201	2282	7	,	,	,
cord-022561-rv5j1201	2282	8	Lymph	Lymph	NNP
cord-022561-rv5j1201	2282	9	Node	Node	NNP
cord-022561-rv5j1201	2282	10	,	,	,
cord-022561-rv5j1201	2282	11	Dog	Dog	NNP
cord-022561-rv5j1201	2282	12	.	.	.
cord-022561-rv5j1201	2283	1	Acute	acute	JJ
cord-022561-rv5j1201	2283	2	lymphadenitis	lymphadenitis	NN
cord-022561-rv5j1201	2283	3	usually	usually	RB
cord-022561-rv5j1201	2283	4	occurs	occur	VBZ
cord-022561-rv5j1201	2283	5	when	when	WRB
cord-022561-rv5j1201	2283	6	a	a	DT
cord-022561-rv5j1201	2283	7	regional	regional	JJ
cord-022561-rv5j1201	2283	8	lymph	lymph	NN
cord-022561-rv5j1201	2283	9	node	node	NN
cord-022561-rv5j1201	2283	10	drains	drain	VBZ
cord-022561-rv5j1201	2283	11	a	a	DT
cord-022561-rv5j1201	2283	12	site	site	NN
cord-022561-rv5j1201	2283	13	of	of	IN
cord-022561-rv5j1201	2283	14	inflammation	inflammation	NN
cord-022561-rv5j1201	2283	15	caused	cause	VBN
cord-022561-rv5j1201	2283	16	by	by	IN
cord-022561-rv5j1201	2283	17	microorganisms	microorganism	NNS
cord-022561-rv5j1201	2283	18	and	and	CC
cord-022561-rv5j1201	2283	19	subsequently	subsequently	RB
cord-022561-rv5j1201	2283	20	becomes	become	VBZ
cord-022561-rv5j1201	2283	21	infected	infected	JJ
cord-022561-rv5j1201	2283	22	.	.	.
cord-022561-rv5j1201	2284	1	The	the	DT
cord-022561-rv5j1201	2284	2	lymph	lymph	NN
cord-022561-rv5j1201	2284	3	node	node	NN
cord-022561-rv5j1201	2284	4	is	be	VBZ
cord-022561-rv5j1201	2284	5	firm	firm	JJ
cord-022561-rv5j1201	2284	6	and	and	CC
cord-022561-rv5j1201	2284	7	enlarged	enlarge	VBN
cord-022561-rv5j1201	2284	8	with	with	IN
cord-022561-rv5j1201	2284	9	a	a	DT
cord-022561-rv5j1201	2284	10	tense	tense	JJ
cord-022561-rv5j1201	2284	11	capsule	capsule	NN
cord-022561-rv5j1201	2284	12	.	.	.
cord-022561-rv5j1201	2285	1	The	the	DT
cord-022561-rv5j1201	2285	2	cut	cut	NN
cord-022561-rv5j1201	2285	3	surface	surface	NN
cord-022561-rv5j1201	2285	4	bulges	bulge	NNS
cord-022561-rv5j1201	2285	5	and	and	CC
cord-022561-rv5j1201	2285	6	is	be	VBZ
cord-022561-rv5j1201	2285	7	wet	wet	JJ
cord-022561-rv5j1201	2285	8	with	with	IN
cord-022561-rv5j1201	2285	9	blood	blood	NN
cord-022561-rv5j1201	2285	10	,	,	,
cord-022561-rv5j1201	2285	11	edema	edema	NN
cord-022561-rv5j1201	2285	12	,	,	,
cord-022561-rv5j1201	2285	13	and	and	CC
cord-022561-rv5j1201	2285	14	an	an	DT
cord-022561-rv5j1201	2285	15	inflammatory	inflammatory	JJ
cord-022561-rv5j1201	2285	16	cell	cell	NN
cord-022561-rv5j1201	2285	17	infiltrate	infiltrate	NN
cord-022561-rv5j1201	2285	18	.	.	.
cord-022561-rv5j1201	2286	1	histoplasmosis	histoplasmosis	NNP
cord-022561-rv5j1201	2286	2	(	(	-LRB-
cord-022561-rv5j1201	2286	3	see	see	VBP
cord-022561-rv5j1201	2286	4	Disorders	disorder	NNS
cord-022561-rv5j1201	2286	5	in	in	IN
cord-022561-rv5j1201	2286	6	Dogs	Dogs	NNP
cord-022561-rv5j1201	2286	7	)	)	-RRB-
cord-022561-rv5j1201	2286	8	.	.	.
cord-022561-rv5j1201	2287	1	In	in	IN
cord-022561-rv5j1201	2287	2	feline	feline	JJ
cord-022561-rv5j1201	2287	3	cryptococcosis	cryptococcosis	NN
cord-022561-rv5j1201	2287	4	(	(	-LRB-
cord-022561-rv5j1201	2287	5	most	most	RBS
cord-022561-rv5j1201	2287	6	often	often	RB
cord-022561-rv5j1201	2287	7	Cryptococcus	Cryptococcus	NNP
cord-022561-rv5j1201	2287	8	neoformans	neoforman	VBZ
cord-022561-rv5j1201	2287	9	)	)	-RRB-
cord-022561-rv5j1201	2287	10	,	,	,
cord-022561-rv5j1201	2287	11	the	the	DT
cord-022561-rv5j1201	2287	12	inflammatory	inflammatory	JJ
cord-022561-rv5j1201	2287	13	response	response	NN
cord-022561-rv5j1201	2287	14	may	may	MD
cord-022561-rv5j1201	2287	15	be	be	VB
cord-022561-rv5j1201	2287	16	mild	mild	JJ
cord-022561-rv5j1201	2287	17	due	due	IN
cord-022561-rv5j1201	2287	18	to	to	IN
cord-022561-rv5j1201	2287	19	the	the	DT
cord-022561-rv5j1201	2287	20	thick	thick	JJ
cord-022561-rv5j1201	2287	21	polysaccharide	polysaccharide	NN
cord-022561-rv5j1201	2287	22	capsule	capsule	NN
cord-022561-rv5j1201	2287	23	,	,	,
cord-022561-rv5j1201	2287	24	which	which	WDT
cord-022561-rv5j1201	2287	25	has	have	VBZ
cord-022561-rv5j1201	2287	26	strong	strong	JJ
cord-022561-rv5j1201	2287	27	immunomodulatory	immunomodulatory	JJ
cord-022561-rv5j1201	2287	28	properties	property	NNS
cord-022561-rv5j1201	2287	29	and	and	CC
cord-022561-rv5j1201	2287	30	promotes	promote	VBZ
cord-022561-rv5j1201	2287	31	immune	immune	JJ
cord-022561-rv5j1201	2287	32	evasion	evasion	NN
cord-022561-rv5j1201	2287	33	and	and	CC
cord-022561-rv5j1201	2287	34	survival	survival	NN
cord-022561-rv5j1201	2287	35	within	within	IN
cord-022561-rv5j1201	2287	36	the	the	DT
cord-022561-rv5j1201	2287	37	host	host	NN
cord-022561-rv5j1201	2287	38	.	.	.
cord-022561-rv5j1201	2288	1	Therefore	therefore	RB
cord-022561-rv5j1201	2288	2	the	the	DT
cord-022561-rv5j1201	2288	3	nodal	nodal	JJ
cord-022561-rv5j1201	2288	4	enlargement	enlargement	NN
cord-022561-rv5j1201	2288	5	is	be	VBZ
cord-022561-rv5j1201	2288	6	due	due	JJ
cord-022561-rv5j1201	2288	7	mainly	mainly	RB
cord-022561-rv5j1201	2288	8	to	to	IN
cord-022561-rv5j1201	2288	9	a	a	DT
cord-022561-rv5j1201	2288	10	large	large	JJ
cord-022561-rv5j1201	2288	11	mass	mass	NN
cord-022561-rv5j1201	2288	12	of	of	IN
cord-022561-rv5j1201	2288	13	organisms	organism	NNS
cord-022561-rv5j1201	2288	14	(	(	-LRB-
cord-022561-rv5j1201	2288	15	see	see	VB
cord-022561-rv5j1201	2288	16	E-	E-	NNP
cord-022561-rv5j1201	2288	17	Fig	Fig	NNP
cord-022561-rv5j1201	2288	18	.	.	.
cord-022561-rv5j1201	2289	1	13	13	CD
cord-022561-rv5j1201	2289	2	-	-	SYM
cord-022561-rv5j1201	2289	3	12	12	CD
cord-022561-rv5j1201	2289	4	)	)	-RRB-
cord-022561-rv5j1201	2289	5	.	.	.
cord-022561-rv5j1201	2290	1	Pigs	pig	NNS
cord-022561-rv5j1201	2290	2	with	with	IN
cord-022561-rv5j1201	2290	3	PCV2	pcv2	JJ
cord-022561-rv5j1201	2290	4	infection	infection	NN
cord-022561-rv5j1201	2290	5	may	may	MD
cord-022561-rv5j1201	2290	6	have	have	VB
cord-022561-rv5j1201	2290	7	a	a	DT
cord-022561-rv5j1201	2290	8	multifocal	multifocal	JJ
cord-022561-rv5j1201	2290	9	to	to	TO
cord-022561-rv5j1201	2290	10	diffuse	diffuse	VB
cord-022561-rv5j1201	2290	11	infiltrate	infiltrate	NN
cord-022561-rv5j1201	2290	12	of	of	IN
cord-022561-rv5j1201	2290	13	macrophages	macrophage	NNS
cord-022561-rv5j1201	2290	14	and	and	CC
cord-022561-rv5j1201	2290	15	multinucleated	multinucleate	VBN
cord-022561-rv5j1201	2290	16	giant	giant	JJ
cord-022561-rv5j1201	2290	17	cells	cell	NNS
cord-022561-rv5j1201	2290	18	of	of	IN
cord-022561-rv5j1201	2290	19	varying	vary	VBG
cord-022561-rv5j1201	2290	20	severity	severity	NN
cord-022561-rv5j1201	2290	21	(	(	-LRB-
cord-022561-rv5j1201	2290	22	see	see	VB
cord-022561-rv5j1201	2290	23	Disorders	disorder	NNS
cord-022561-rv5j1201	2290	24	of	of	IN
cord-022561-rv5j1201	2290	25	Pigs	pig	NNS
cord-022561-rv5j1201	2290	26	)	)	-RRB-
cord-022561-rv5j1201	2290	27	.	.	.
cord-022561-rv5j1201	2291	1	Secondary	secondary	JJ
cord-022561-rv5j1201	2291	2	(	(	-LRB-
cord-022561-rv5j1201	2291	3	Metastatic	Metastatic	NNP
cord-022561-rv5j1201	2291	4	)	)	-RRB-
cord-022561-rv5j1201	2291	5	Neoplasms	Neoplasms	NNP
cord-022561-rv5j1201	2291	6	.	.	.
cord-022561-rv5j1201	2292	1	Carcinomas	carcinoma	NNS
cord-022561-rv5j1201	2292	2	typically	typically	RB
cord-022561-rv5j1201	2292	3	metastasize	metastasize	VBP
cord-022561-rv5j1201	2292	4	via	via	IN
cord-022561-rv5j1201	2292	5	lymphatic	lymphatic	JJ
cord-022561-rv5j1201	2292	6	vessels	vessel	NNS
cord-022561-rv5j1201	2292	7	to	to	IN
cord-022561-rv5j1201	2292	8	the	the	DT
cord-022561-rv5j1201	2292	9	regional	regional	JJ
cord-022561-rv5j1201	2292	10	lymph	lymph	NN
cord-022561-rv5j1201	2292	11	node	node	NN
cord-022561-rv5j1201	2292	12	.	.	.
cord-022561-rv5j1201	2293	1	Other	other	JJ
cord-022561-rv5j1201	2293	2	common	common	JJ
cord-022561-rv5j1201	2293	3	metastatic	metastatic	JJ
cord-022561-rv5j1201	2293	4	neoplasms	neoplasm	NNS
cord-022561-rv5j1201	2293	5	include	include	VBP
cord-022561-rv5j1201	2293	6	mast	mast	JJ
cord-022561-rv5j1201	2293	7	cell	cell	NN
cord-022561-rv5j1201	2293	8	tumor	tumor	NN
cord-022561-rv5j1201	2293	9	and	and	CC
cord-022561-rv5j1201	2293	10	malignant	malignant	JJ
cord-022561-rv5j1201	2293	11	melanoma	melanoma	NN
cord-022561-rv5j1201	2293	12	.	.	.
cord-022561-rv5j1201	2294	1	Although	although	IN
cord-022561-rv5j1201	2294	2	sarcomas	sarcoma	NNS
cord-022561-rv5j1201	2294	3	most	most	RBS
cord-022561-rv5j1201	2294	4	often	often	RB
cord-022561-rv5j1201	2294	5	metastasize	metastasize	VBP
cord-022561-rv5j1201	2294	6	hematogenously	hematogenously	RB
cord-022561-rv5j1201	2294	7	,	,	,
cord-022561-rv5j1201	2294	8	some	some	DT
cord-022561-rv5j1201	2294	9	more	more	RBR
cord-022561-rv5j1201	2294	10	aggressive	aggressive	JJ
cord-022561-rv5j1201	2294	11	sarcomas	sarcoma	NNS
cord-022561-rv5j1201	2294	12	(	(	-LRB-
cord-022561-rv5j1201	2294	13	e.g.	e.g.	RB
cord-022561-rv5j1201	2294	14	,	,	,
cord-022561-rv5j1201	2294	15	osteosarcoma	osteosarcoma	NN
cord-022561-rv5j1201	2294	16	)	)	-RRB-
cord-022561-rv5j1201	2294	17	may	may	MD
cord-022561-rv5j1201	2294	18	spread	spread	VB
cord-022561-rv5j1201	2294	19	to	to	IN
cord-022561-rv5j1201	2294	20	regional	regional	JJ
cord-022561-rv5j1201	2294	21	lymph	lymph	NN
cord-022561-rv5j1201	2294	22	nodes	node	NNS
cord-022561-rv5j1201	2294	23	.	.	.
cord-022561-rv5j1201	2295	1	Histologically	histologically	RB
cord-022561-rv5j1201	2295	2	,	,	,
cord-022561-rv5j1201	2295	3	single	single	JJ
cord-022561-rv5j1201	2295	4	cells	cell	NNS
cord-022561-rv5j1201	2295	5	or	or	CC
cord-022561-rv5j1201	2295	6	clusters	cluster	NNS
cord-022561-rv5j1201	2295	7	of	of	IN
cord-022561-rv5j1201	2295	8	neoplastic	neoplastic	JJ
cord-022561-rv5j1201	2295	9	cells	cell	NNS
cord-022561-rv5j1201	2295	10	travel	travel	VBP
cord-022561-rv5j1201	2295	11	via	via	IN
cord-022561-rv5j1201	2295	12	the	the	DT
cord-022561-rv5j1201	2295	13	afferent	afferent	JJ
cord-022561-rv5j1201	2295	14	lymphatic	lymphatic	NN
cord-022561-rv5j1201	2295	15	vessels	vessel	NNS
cord-022561-rv5j1201	2295	16	and	and	CC
cord-022561-rv5j1201	2295	17	are	be	VBP
cord-022561-rv5j1201	2295	18	deposited	deposit	VBN
cord-022561-rv5j1201	2295	19	in	in	IN
cord-022561-rv5j1201	2295	20	a	a	DT
cord-022561-rv5j1201	2295	21	sinus	sinus	NN
cord-022561-rv5j1201	2295	22	,	,	.
cord-022561-rv5j1201	2296	1	usually	usually	RB
cord-022561-rv5j1201	2296	2	the	the	DT
cord-022561-rv5j1201	2296	3	subcapsular	subcapsular	NNP
cord-022561-rv5j1201	2296	4	sinus	sinus	NNP
cord-022561-rv5j1201	2296	5	(	(	-LRB-
cord-022561-rv5j1201	2296	6	see	see	VB
cord-022561-rv5j1201	2296	7	Fig	Fig	NNP
cord-022561-rv5j1201	2296	8	.	.	.
cord-022561-rv5j1201	2296	9	 	 	_SP
cord-022561-rv5j1201	2296	10	13	13	CD
cord-022561-rv5j1201	2296	11	-47	-47	CD
cord-022561-rv5j1201	2296	12	)	)	-RRB-
cord-022561-rv5j1201	2296	13	.	.	.
cord-022561-rv5j1201	2297	1	Here	here	RB
cord-022561-rv5j1201	2297	2	the	the	DT
cord-022561-rv5j1201	2297	3	cells	cell	NNS
cord-022561-rv5j1201	2297	4	proliferate	proliferate	VBP
cord-022561-rv5j1201	2297	5	and	and	CC
cord-022561-rv5j1201	2297	6	can	can	MD
cord-022561-rv5j1201	2297	7	ultimately	ultimately	RB
cord-022561-rv5j1201	2297	8	occupy	occupy	VB
cord-022561-rv5j1201	2297	9	the	the	DT
cord-022561-rv5j1201	2297	10	whole	whole	JJ
cord-022561-rv5j1201	2297	11	lymph	lymph	NN
cord-022561-rv5j1201	2297	12	node	node	NN
cord-022561-rv5j1201	2297	13	,	,	,
cord-022561-rv5j1201	2297	14	as	as	RB
cord-022561-rv5j1201	2297	15	well	well	RB
cord-022561-rv5j1201	2297	16	as	as	IN
cord-022561-rv5j1201	2297	17	drain	drain	NN
cord-022561-rv5j1201	2297	18	to	to	IN
cord-022561-rv5j1201	2297	19	the	the	DT
cord-022561-rv5j1201	2297	20	next	next	JJ
cord-022561-rv5j1201	2297	21	lymph	lymph	NN
cord-022561-rv5j1201	2297	22	node	node	NN
cord-022561-rv5j1201	2297	23	in	in	IN
cord-022561-rv5j1201	2297	24	the	the	DT
cord-022561-rv5j1201	2297	25	chain	chain	NN
cord-022561-rv5j1201	2297	26	.	.	.
cord-022561-rv5j1201	2298	1	tuberculosis	tuberculosis	NN
cord-022561-rv5j1201	2298	2	)	)	-RRB-
cord-022561-rv5j1201	2298	3	,	,	,
cord-022561-rv5j1201	2298	4	but	but	CC
cord-022561-rv5j1201	2298	5	once	once	RB
cord-022561-rv5j1201	2298	6	disseminated	disseminate	VBN
cord-022561-rv5j1201	2298	7	in	in	IN
cord-022561-rv5j1201	2298	8	the	the	DT
cord-022561-rv5j1201	2298	9	lymph	lymph	NN
cord-022561-rv5j1201	2298	10	or	or	CC
cord-022561-rv5j1201	2298	11	blood	blood	NN
cord-022561-rv5j1201	2298	12	,	,	,
cord-022561-rv5j1201	2298	13	lymph	lymph	NN
cord-022561-rv5j1201	2298	14	nodes	node	NNS
cord-022561-rv5j1201	2298	15	throughout	throughout	IN
cord-022561-rv5j1201	2298	16	the	the	DT
cord-022561-rv5j1201	2298	17	body	body	NN
cord-022561-rv5j1201	2298	18	will	will	MD
cord-022561-rv5j1201	2298	19	have	have	VB
cord-022561-rv5j1201	2298	20	lesions	lesion	NNS
cord-022561-rv5j1201	2298	21	.	.	.
cord-022561-rv5j1201	2299	1	Well	well	RB
cord-022561-rv5j1201	2299	2	-	-	HYPH
cord-022561-rv5j1201	2299	3	organized	organize	VBN
cord-022561-rv5j1201	2299	4	granulomas	granuloma	NNS
cord-022561-rv5j1201	2299	5	consist	consist	VBP
cord-022561-rv5j1201	2299	6	of	of	IN
cord-022561-rv5j1201	2299	7	a	a	DT
cord-022561-rv5j1201	2299	8	central	central	JJ
cord-022561-rv5j1201	2299	9	mass	mass	NN
cord-022561-rv5j1201	2299	10	of	of	IN
cord-022561-rv5j1201	2299	11	macrophages	macrophage	NNS
cord-022561-rv5j1201	2299	12	with	with	IN
cord-022561-rv5j1201	2299	13	phagocytized	phagocytized	JJ
cord-022561-rv5j1201	2299	14	mycobacteria	mycobacterium	NNS
cord-022561-rv5j1201	2299	15	,	,	,
cord-022561-rv5j1201	2299	16	surrounded	surround	VBN
cord-022561-rv5j1201	2299	17	by	by	IN
cord-022561-rv5j1201	2299	18	epithelioid	epithelioid	NNP
cord-022561-rv5j1201	2299	19	and	and	CC
cord-022561-rv5j1201	2299	20	foamy	foamy	NN
cord-022561-rv5j1201	2299	21	macrophages	macrophage	NNS
cord-022561-rv5j1201	2299	22	and	and	CC
cord-022561-rv5j1201	2299	23	occasional	occasional	JJ
cord-022561-rv5j1201	2299	24	multinucleated	multinucleated	JJ
cord-022561-rv5j1201	2299	25	giant	giant	JJ
cord-022561-rv5j1201	2299	26	cells	cell	NNS
cord-022561-rv5j1201	2299	27	(	(	-LRB-
cord-022561-rv5j1201	2299	28	Langhans	Langhans	NNP
cord-022561-rv5j1201	2299	29	type	type	NN
cord-022561-rv5j1201	2299	30	)	)	-RRB-
cord-022561-rv5j1201	2299	31	.	.	.
cord-022561-rv5j1201	2300	1	These	these	DT
cord-022561-rv5j1201	2300	2	inflammatory	inflammatory	JJ
cord-022561-rv5j1201	2300	3	nodules	nodule	NNS
cord-022561-rv5j1201	2300	4	are	be	VBP
cord-022561-rv5j1201	2300	5	surrounded	surround	VBN
cord-022561-rv5j1201	2300	6	by	by	IN
cord-022561-rv5j1201	2300	7	a	a	DT
cord-022561-rv5j1201	2300	8	layer	layer	NN
cord-022561-rv5j1201	2300	9	of	of	IN
cord-022561-rv5j1201	2300	10	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	2300	11	enclosed	enclose	VBN
cord-022561-rv5j1201	2300	12	in	in	IN
cord-022561-rv5j1201	2300	13	a	a	DT
cord-022561-rv5j1201	2300	14	fibrous	fibrous	JJ
cord-022561-rv5j1201	2300	15	capsule	capsule	NN
cord-022561-rv5j1201	2300	16	.	.	.
cord-022561-rv5j1201	2301	1	Over	over	IN
cord-022561-rv5j1201	2301	2	time	time	NN
cord-022561-rv5j1201	2301	3	the	the	DT
cord-022561-rv5j1201	2301	4	center	center	NN
cord-022561-rv5j1201	2301	5	of	of	IN
cord-022561-rv5j1201	2301	6	the	the	DT
cord-022561-rv5j1201	2301	7	granuloma	granuloma	NN
cord-022561-rv5j1201	2301	8	may	may	MD
cord-022561-rv5j1201	2301	9	undergo	undergo	VB
cord-022561-rv5j1201	2301	10	caseous	caseous	JJ
cord-022561-rv5j1201	2301	11	necrosis	necrosis	NN
cord-022561-rv5j1201	2301	12	due	due	IN
cord-022561-rv5j1201	2301	13	to	to	IN
cord-022561-rv5j1201	2301	14	the	the	DT
cord-022561-rv5j1201	2301	15	high	high	JJ
cord-022561-rv5j1201	2301	16	lipid	lipid	NN
cord-022561-rv5j1201	2301	17	and	and	CC
cord-022561-rv5j1201	2301	18	protein	protein	NN
cord-022561-rv5j1201	2301	19	content	content	NN
cord-022561-rv5j1201	2301	20	of	of	IN
cord-022561-rv5j1201	2301	21	the	the	DT
cord-022561-rv5j1201	2301	22	dead	dead	JJ
cord-022561-rv5j1201	2301	23	macrophages	macrophage	NNS
cord-022561-rv5j1201	2301	24	(	(	-LRB-
cord-022561-rv5j1201	2301	25	see	see	VB
cord-022561-rv5j1201	2301	26	Chapter	chapter	NN
cord-022561-rv5j1201	2301	27	3	3	CD
cord-022561-rv5j1201	2301	28	)	)	-RRB-
cord-022561-rv5j1201	2301	29	.	.	.
cord-022561-rv5j1201	2302	1	In	in	IN
cord-022561-rv5j1201	2302	2	bovine	bovine	JJ
cord-022561-rv5j1201	2302	3	Johne	Johne	NNP
cord-022561-rv5j1201	2302	4	's	's	POS
cord-022561-rv5j1201	2302	5	disease	disease	NN
cord-022561-rv5j1201	2302	6	the	the	DT
cord-022561-rv5j1201	2302	7	mesenteric	mesenteric	JJ
cord-022561-rv5j1201	2302	8	lymph	lymph	NN
cord-022561-rv5j1201	2302	9	nodes	node	NNS
cord-022561-rv5j1201	2302	10	draining	drain	VBG
cord-022561-rv5j1201	2302	11	the	the	DT
cord-022561-rv5j1201	2302	12	infected	infect	VBN
cord-022561-rv5j1201	2302	13	intestine	intestine	NN
cord-022561-rv5j1201	2302	14	can	can	MD
cord-022561-rv5j1201	2302	15	have	have	VB
cord-022561-rv5j1201	2302	16	noncaseous	noncaseous	JJ
cord-022561-rv5j1201	2302	17	granulomas	granuloma	NNS
cord-022561-rv5j1201	2302	18	(	(	-LRB-
cord-022561-rv5j1201	2302	19	Fig	Fig	NNP
cord-022561-rv5j1201	2302	20	.	.	.
cord-022561-rv5j1201	2302	21	13	13	CD
cord-022561-rv5j1201	2302	22	-	-	SYM
cord-022561-rv5j1201	2302	23	82	82	CD
cord-022561-rv5j1201	2302	24	)	)	-RRB-
cord-022561-rv5j1201	2302	25	.	.	.
cord-022561-rv5j1201	2303	1	Diffuse	Diffuse	NNP
cord-022561-rv5j1201	2303	2	Granulomatous	Granulomatous	NNP
cord-022561-rv5j1201	2303	3	Lymphadenitis	Lymphadenitis	NNP
cord-022561-rv5j1201	2303	4	.	.	.
cord-022561-rv5j1201	2304	1	Coalescing	coalesce	VBG
cord-022561-rv5j1201	2304	2	to	to	TO
cord-022561-rv5j1201	2304	3	diffuse	diffuse	VB
cord-022561-rv5j1201	2304	4	granulomatous	granulomatous	JJ
cord-022561-rv5j1201	2304	5	lymphadenitis	lymphadenitis	NN
cord-022561-rv5j1201	2304	6	is	be	VBZ
cord-022561-rv5j1201	2304	7	seen	see	VBN
cord-022561-rv5j1201	2304	8	in	in	IN
cord-022561-rv5j1201	2304	9	disseminated	disseminate	VBN
cord-022561-rv5j1201	2304	10	fungal	fungal	JJ
cord-022561-rv5j1201	2304	11	infections	infection	NNS
cord-022561-rv5j1201	2304	12	such	such	JJ
cord-022561-rv5j1201	2304	13	as	as	IN
cord-022561-rv5j1201	2304	14	blastomycosis	blastomycosis	NNP
cord-022561-rv5j1201	2304	15	,	,	,
cord-022561-rv5j1201	2304	16	cryptococcosis	cryptococcosis	NNP
cord-022561-rv5j1201	2304	17	(	(	-LRB-
cord-022561-rv5j1201	2304	18	E-	E-	NNP
cord-022561-rv5j1201	2304	19	Fig	Fig	NNP
cord-022561-rv5j1201	2304	20	.	.	.
cord-022561-rv5j1201	2305	1	13	13	CD
cord-022561-rv5j1201	2305	2	-	-	SYM
cord-022561-rv5j1201	2305	3	12	12	CD
cord-022561-rv5j1201	2305	4	)	)	-RRB-
cord-022561-rv5j1201	2305	5	,	,	,
cord-022561-rv5j1201	2305	6	and	and	CC
cord-022561-rv5j1201	2305	7	extent	extent	NN
cord-022561-rv5j1201	2305	8	of	of	IN
cord-022561-rv5j1201	2305	9	the	the	DT
cord-022561-rv5j1201	2305	10	emphysema	emphysema	NN
cord-022561-rv5j1201	2305	11	.	.	.
cord-022561-rv5j1201	2306	1	In	in	IN
cord-022561-rv5j1201	2306	2	severe	severe	JJ
cord-022561-rv5j1201	2306	3	cases	case	NNS
cord-022561-rv5j1201	2306	4	the	the	DT
cord-022561-rv5j1201	2306	5	lymph	lymph	NN
cord-022561-rv5j1201	2306	6	node	node	NN
cord-022561-rv5j1201	2306	7	is	be	VBZ
cord-022561-rv5j1201	2306	8	light	light	JJ
cord-022561-rv5j1201	2306	9	,	,	,
cord-022561-rv5j1201	2306	10	puffy	puffy	JJ
cord-022561-rv5j1201	2306	11	,	,	,
cord-022561-rv5j1201	2306	12	and	and	CC
cord-022561-rv5j1201	2306	13	filled	fill	VBN
cord-022561-rv5j1201	2306	14	with	with	IN
cord-022561-rv5j1201	2306	15	discrete	discrete	JJ
cord-022561-rv5j1201	2306	16	gas	gas	NN
cord-022561-rv5j1201	2306	17	bubbles	bubble	NNS
cord-022561-rv5j1201	2306	18	,	,	,
cord-022561-rv5j1201	2306	19	and	and	CC
cord-022561-rv5j1201	2306	20	the	the	DT
cord-022561-rv5j1201	2306	21	cut	cut	NN
cord-022561-rv5j1201	2306	22	surface	surface	NN
cord-022561-rv5j1201	2306	23	may	may	MD
cord-022561-rv5j1201	2306	24	be	be	VB
cord-022561-rv5j1201	2306	25	spongy	spongy	JJ
cord-022561-rv5j1201	2306	26	.	.	.
cord-022561-rv5j1201	2307	1	Histologically	histologically	RB
cord-022561-rv5j1201	2307	2	,	,	,
cord-022561-rv5j1201	2307	3	the	the	DT
cord-022561-rv5j1201	2307	4	sinuses	sinus	NNS
cord-022561-rv5j1201	2307	5	are	be	VBP
cord-022561-rv5j1201	2307	6	distended	distend	VBN
cord-022561-rv5j1201	2307	7	with	with	IN
cord-022561-rv5j1201	2307	8	gas	gas	NN
cord-022561-rv5j1201	2307	9	and	and	CC
cord-022561-rv5j1201	2307	10	lined	line	VBN
cord-022561-rv5j1201	2307	11	by	by	IN
cord-022561-rv5j1201	2307	12	macrophages	macrophage	NNS
cord-022561-rv5j1201	2307	13	and	and	CC
cord-022561-rv5j1201	2307	14	giant	giant	JJ
cord-022561-rv5j1201	2307	15	cells	cell	NNS
cord-022561-rv5j1201	2307	16	.	.	.
cord-022561-rv5j1201	2308	1	This	this	DT
cord-022561-rv5j1201	2308	2	change	change	NN
cord-022561-rv5j1201	2308	3	has	have	VBZ
cord-022561-rv5j1201	2308	4	been	be	VBN
cord-022561-rv5j1201	2308	5	considered	consider	VBN
cord-022561-rv5j1201	2308	6	a	a	DT
cord-022561-rv5j1201	2308	7	foreign	foreign	JJ
cord-022561-rv5j1201	2308	8	body	body	NN
cord-022561-rv5j1201	2308	9	reaction	reaction	NN
cord-022561-rv5j1201	2308	10	to	to	IN
cord-022561-rv5j1201	2308	11	the	the	DT
cord-022561-rv5j1201	2308	12	gas	gas	NN
cord-022561-rv5j1201	2308	13	bubbles	bubble	NNS
cord-022561-rv5j1201	2308	14	.	.	.
cord-022561-rv5j1201	2309	1	Macrophages	macrophage	NNS
cord-022561-rv5j1201	2309	2	and	and	CC
cord-022561-rv5j1201	2309	3	giant	giant	JJ
cord-022561-rv5j1201	2309	4	cells	cell	NNS
cord-022561-rv5j1201	2309	5	are	be	VBP
cord-022561-rv5j1201	2309	6	also	also	RB
cord-022561-rv5j1201	2309	7	seen	see	VBN
cord-022561-rv5j1201	2309	8	in	in	IN
cord-022561-rv5j1201	2309	9	afferent	afferent	JJ
cord-022561-rv5j1201	2309	10	lymphatic	lymphatic	NN
cord-022561-rv5j1201	2309	11	vessels	vessel	NNS
cord-022561-rv5j1201	2309	12	(	(	-LRB-
cord-022561-rv5j1201	2309	13	granulomatous	granulomatous	JJ
cord-022561-rv5j1201	2309	14	lymphangitis	lymphangitis	NNP
cord-022561-rv5j1201	2309	15	)	)	-RRB-
cord-022561-rv5j1201	2309	16	.	.	.
cord-022561-rv5j1201	2310	1	Vascular	vascular	JJ
cord-022561-rv5j1201	2310	2	Transformation	transformation	NN
cord-022561-rv5j1201	2310	3	of	of	IN
cord-022561-rv5j1201	2310	4	Lymph	Lymph	NNP
cord-022561-rv5j1201	2310	5	Node	Node	NNP
cord-022561-rv5j1201	2310	6	Sinus	Sinus	NNP
cord-022561-rv5j1201	2310	7	(	(	-LRB-
cord-022561-rv5j1201	2310	8	Nodal	Nodal	NNP
cord-022561-rv5j1201	2310	9	Angiomatosis	Angiomatosis	NNP
cord-022561-rv5j1201	2310	10	)	)	-RRB-
cord-022561-rv5j1201	2310	11	.	.	.
cord-022561-rv5j1201	2311	1	Vascular	vascular	JJ
cord-022561-rv5j1201	2311	2	transformation	transformation	NN
cord-022561-rv5j1201	2311	3	of	of	IN
cord-022561-rv5j1201	2311	4	the	the	DT
cord-022561-rv5j1201	2311	5	sinuses	sinus	NNS
cord-022561-rv5j1201	2311	6	is	be	VBZ
cord-022561-rv5j1201	2311	7	a	a	DT
cord-022561-rv5j1201	2311	8	nonneoplastic	nonneoplastic	JJ
cord-022561-rv5j1201	2311	9	reaction	reaction	NN
cord-022561-rv5j1201	2311	10	to	to	IN
cord-022561-rv5j1201	2311	11	blocked	block	VBN
cord-022561-rv5j1201	2311	12	efferent	efferent	JJ
cord-022561-rv5j1201	2311	13	lymphatic	lymphatic	JJ
cord-022561-rv5j1201	2311	14	vessels	vessel	NNS
cord-022561-rv5j1201	2311	15	or	or	CC
cord-022561-rv5j1201	2311	16	veins	vein	NNS
cord-022561-rv5j1201	2311	17	.	.	.
cord-022561-rv5j1201	2312	1	This	this	DT
cord-022561-rv5j1201	2312	2	pressure	pressure	NN
cord-022561-rv5j1201	2312	3	-	-	HYPH
cord-022561-rv5j1201	2312	4	induced	induce	VBN
cord-022561-rv5j1201	2312	5	lesion	lesion	NN
cord-022561-rv5j1201	2312	6	results	result	NNS
cord-022561-rv5j1201	2312	7	in	in	IN
cord-022561-rv5j1201	2312	8	the	the	DT
cord-022561-rv5j1201	2312	9	formation	formation	NN
cord-022561-rv5j1201	2312	10	of	of	IN
cord-022561-rv5j1201	2312	11	anastomosing	anastomosing	JJ
cord-022561-rv5j1201	2312	12	vascular	vascular	JJ
cord-022561-rv5j1201	2312	13	channels	channel	NNS
cord-022561-rv5j1201	2312	14	and	and	CC
cord-022561-rv5j1201	2312	15	may	may	MD
cord-022561-rv5j1201	2312	16	be	be	VB
cord-022561-rv5j1201	2312	17	confused	confuse	VBN
cord-022561-rv5j1201	2312	18	with	with	IN
cord-022561-rv5j1201	2312	19	a	a	DT
cord-022561-rv5j1201	2312	20	nodal	nodal	JJ
cord-022561-rv5j1201	2312	21	vascular	vascular	JJ
cord-022561-rv5j1201	2312	22	neoplasm	neoplasm	NN
cord-022561-rv5j1201	2312	23	.	.	.
cord-022561-rv5j1201	2313	1	These	these	DT
cord-022561-rv5j1201	2313	2	proliferative	proliferative	JJ
cord-022561-rv5j1201	2313	3	but	but	CC
cord-022561-rv5j1201	2313	4	noninvasive	noninvasive	JJ
cord-022561-rv5j1201	2313	5	masses	masse	NNS
cord-022561-rv5j1201	2313	6	usually	usually	RB
cord-022561-rv5j1201	2313	7	begin	begin	VBP
cord-022561-rv5j1201	2313	8	in	in	IN
cord-022561-rv5j1201	2313	9	the	the	DT
cord-022561-rv5j1201	2313	10	subcapsular	subcapsular	JJ
cord-022561-rv5j1201	2313	11	sinuses	sinus	NNS
cord-022561-rv5j1201	2313	12	and	and	CC
cord-022561-rv5j1201	2313	13	may	may	MD
cord-022561-rv5j1201	2313	14	be	be	VB
cord-022561-rv5j1201	2313	15	followed	follow	VBN
cord-022561-rv5j1201	2313	16	by	by	IN
cord-022561-rv5j1201	2313	17	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	2313	18	atrophy	atrophy	NN
cord-022561-rv5j1201	2313	19	,	,	,
cord-022561-rv5j1201	2313	20	erythrophagocytosis	erythrophagocytosis	NNP
cord-022561-rv5j1201	2313	21	/	/	SYM
cord-022561-rv5j1201	2313	22	hemosiderosis	hemosiderosis	NNP
cord-022561-rv5j1201	2313	23	,	,	,
cord-022561-rv5j1201	2313	24	and	and	CC
cord-022561-rv5j1201	2313	25	fibrosis	fibrosis	NN
cord-022561-rv5j1201	2313	26	.	.	.
cord-022561-rv5j1201	2314	1	The	the	DT
cord-022561-rv5j1201	2314	2	blockage	blockage	NN
cord-022561-rv5j1201	2314	3	may	may	MD
cord-022561-rv5j1201	2314	4	be	be	VB
cord-022561-rv5j1201	2314	5	caused	cause	VBN
cord-022561-rv5j1201	2314	6	by	by	IN
cord-022561-rv5j1201	2314	7	malignant	malignant	JJ
cord-022561-rv5j1201	2314	8	neoplasms	neoplasm	NNS
cord-022561-rv5j1201	2314	9	of	of	IN
cord-022561-rv5j1201	2314	10	the	the	DT
cord-022561-rv5j1201	2314	11	tissues	tissue	NNS
cord-022561-rv5j1201	2314	12	that	that	WDT
cord-022561-rv5j1201	2314	13	the	the	DT
cord-022561-rv5j1201	2314	14	lymph	lymph	NN
cord-022561-rv5j1201	2314	15	node	node	NN
cord-022561-rv5j1201	2314	16	drains	drain	NNS
cord-022561-rv5j1201	2314	17	(	(	-LRB-
cord-022561-rv5j1201	2314	18	e.g.	e.g.	RB
cord-022561-rv5j1201	2314	19	,	,	,
cord-022561-rv5j1201	2314	20	thyroid	thyroid	NN
cord-022561-rv5j1201	2314	21	carcinoma	carcinoma	NN
cord-022561-rv5j1201	2314	22	with	with	IN
cord-022561-rv5j1201	2314	23	nodal	nodal	JJ
cord-022561-rv5j1201	2314	24	angiomatosis	angiomatosis	NN
cord-022561-rv5j1201	2314	25	of	of	IN
cord-022561-rv5j1201	2314	26	the	the	DT
cord-022561-rv5j1201	2314	27	mandibular	mandibular	JJ
cord-022561-rv5j1201	2314	28	lymph	lymph	NN
cord-022561-rv5j1201	2314	29	node	node	NN
cord-022561-rv5j1201	2314	30	)	)	-RRB-
cord-022561-rv5j1201	2314	31	.	.	.
cord-022561-rv5j1201	2315	1	See	see	VB
cord-022561-rv5j1201	2315	2	section	section	NN
cord-022561-rv5j1201	2315	3	on	on	IN
cord-022561-rv5j1201	2315	4	Bone	Bone	NNP
cord-022561-rv5j1201	2315	5	Marrow	Marrow	NNP
cord-022561-rv5j1201	2315	6	,	,	,
cord-022561-rv5j1201	2315	7	Disorders	disorder	NNS
cord-022561-rv5j1201	2315	8	of	of	IN
cord-022561-rv5j1201	2315	9	Domestic	domestic	JJ
cord-022561-rv5j1201	2315	10	Animals	Animals	NNPS
cord-022561-rv5j1201	2315	11	,	,	,
cord-022561-rv5j1201	2315	12	Hematopoietic	Hematopoietic	NNP
cord-022561-rv5j1201	2315	13	Neoplasia	Neoplasia	NNP
cord-022561-rv5j1201	2315	14	for	for	IN
cord-022561-rv5j1201	2315	15	a	a	DT
cord-022561-rv5j1201	2315	16	discussion	discussion	NN
cord-022561-rv5j1201	2315	17	of	of	IN
cord-022561-rv5j1201	2315	18	the	the	DT
cord-022561-rv5j1201	2315	19	WHO	WHO	NNP
cord-022561-rv5j1201	2315	20	classification	classification	NN
cord-022561-rv5j1201	2315	21	of	of	IN
cord-022561-rv5j1201	2315	22	hematopoietic	hematopoietic	JJ
cord-022561-rv5j1201	2315	23	neoplasia	neoplasia	NN
cord-022561-rv5j1201	2315	24	that	that	WDT
cord-022561-rv5j1201	2315	25	predominantly	predominantly	RB
cord-022561-rv5j1201	2315	26	arise	arise	VBP
cord-022561-rv5j1201	2315	27	and	and	CC
cord-022561-rv5j1201	2315	28	proliferate	proliferate	VBP
cord-022561-rv5j1201	2315	29	within	within	IN
cord-022561-rv5j1201	2315	30	bone	bone	NN
cord-022561-rv5j1201	2315	31	marrow	marrow	NN
cord-022561-rv5j1201	2315	32	.	.	.
cord-022561-rv5j1201	2316	1	This	this	DT
cord-022561-rv5j1201	2316	2	section	section	NN
cord-022561-rv5j1201	2316	3	will	will	MD
cord-022561-rv5j1201	2316	4	cover	cover	VB
cord-022561-rv5j1201	2316	5	neoplasms	neoplasm	NNS
cord-022561-rv5j1201	2316	6	of	of	IN
cord-022561-rv5j1201	2316	7	lymphoid	lymphoid	NN
cord-022561-rv5j1201	2316	8	tissue(s	tissue(s	NN
cord-022561-rv5j1201	2316	9	)	)	-RRB-
cord-022561-rv5j1201	2316	10	arising	arise	VBG
cord-022561-rv5j1201	2316	11	outside	outside	IN
cord-022561-rv5j1201	2316	12	of	of	IN
cord-022561-rv5j1201	2316	13	bone	bone	NN
cord-022561-rv5j1201	2316	14	marrow	marrow	NN
cord-022561-rv5j1201	2316	15	.	.	.
cord-022561-rv5j1201	2317	1	Lymphoma	Lymphoma	NNP
cord-022561-rv5j1201	2317	2	.	.	.
cord-022561-rv5j1201	2318	1	The	the	DT
cord-022561-rv5j1201	2318	2	term	term	NN
cord-022561-rv5j1201	2318	3	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2318	4	(	(	-LRB-
cord-022561-rv5j1201	2318	5	also	also	RB
cord-022561-rv5j1201	2318	6	known	know	VBN
cord-022561-rv5j1201	2318	7	as	as	IN
cord-022561-rv5j1201	2318	8	lymphosarcoma	lymphosarcoma	NNP
cord-022561-rv5j1201	2318	9	)	)	-RRB-
cord-022561-rv5j1201	2318	10	encompasses	encompass	VBZ
cord-022561-rv5j1201	2318	11	a	a	DT
cord-022561-rv5j1201	2318	12	diverse	diverse	JJ
cord-022561-rv5j1201	2318	13	group	group	NN
cord-022561-rv5j1201	2318	14	of	of	IN
cord-022561-rv5j1201	2318	15	malignancies	malignancy	NNS
cord-022561-rv5j1201	2318	16	arising	arise	VBG
cord-022561-rv5j1201	2318	17	in	in	IN
cord-022561-rv5j1201	2318	18	lymphoid	lymphoid	NN
cord-022561-rv5j1201	2318	19	tissue(s	tissue(s	NN
cord-022561-rv5j1201	2318	20	)	)	-RRB-
cord-022561-rv5j1201	2318	21	outside	outside	IN
cord-022561-rv5j1201	2318	22	of	of	IN
cord-022561-rv5j1201	2318	23	bone	bone	NN
cord-022561-rv5j1201	2318	24	marrow	marrow	NN
cord-022561-rv5j1201	2318	25	.	.	.
cord-022561-rv5j1201	2319	1	Grossly	grossly	RB
cord-022561-rv5j1201	2319	2	,	,	,
cord-022561-rv5j1201	2319	3	there	there	EX
cord-022561-rv5j1201	2319	4	may	may	MD
cord-022561-rv5j1201	2319	5	be	be	VB
cord-022561-rv5j1201	2319	6	diffuse	diffuse	JJ
cord-022561-rv5j1201	2319	7	to	to	IN
cord-022561-rv5j1201	2319	8	nodular	nodular	JJ
cord-022561-rv5j1201	2319	9	enlargement	enlargement	NN
cord-022561-rv5j1201	2319	10	of	of	IN
cord-022561-rv5j1201	2319	11	one	one	CD
cord-022561-rv5j1201	2319	12	or	or	CC
cord-022561-rv5j1201	2319	13	more	more	JJR
cord-022561-rv5j1201	2319	14	lymph	lymph	NN
cord-022561-rv5j1201	2319	15	nodes	node	NNS
cord-022561-rv5j1201	2319	16	(	(	-LRB-
cord-022561-rv5j1201	2319	17	Fig	Fig	NNP
cord-022561-rv5j1201	2319	18	.	.	.
cord-022561-rv5j1201	2319	19	13	13	CD
cord-022561-rv5j1201	2319	20	-	-	SYM
cord-022561-rv5j1201	2319	21	83	83	CD
cord-022561-rv5j1201	2319	22	)	)	-RRB-
cord-022561-rv5j1201	2319	23	,	,	,
cord-022561-rv5j1201	2319	24	and	and	CC
cord-022561-rv5j1201	2319	25	the	the	DT
cord-022561-rv5j1201	2319	26	cut	cut	NN
cord-022561-rv5j1201	2319	27	surface	surface	NN
cord-022561-rv5j1201	2319	28	is	be	VBZ
cord-022561-rv5j1201	2319	29	soft	soft	JJ
cord-022561-rv5j1201	2319	30	,	,	,
cord-022561-rv5j1201	2319	31	white	white	JJ
cord-022561-rv5j1201	2319	32	,	,	,
cord-022561-rv5j1201	2319	33	and	and	CC
cord-022561-rv5j1201	2319	34	bulging	bulge	VBG
cord-022561-rv5j1201	2319	35	with	with	IN
cord-022561-rv5j1201	2319	36	loss	loss	NN
cord-022561-rv5j1201	2319	37	of	of	IN
cord-022561-rv5j1201	2319	38	normal	normal	JJ
cord-022561-rv5j1201	2319	39	corticomedullary	corticomedullary	JJ
cord-022561-rv5j1201	2319	40	architecture	architecture	NN
cord-022561-rv5j1201	2319	41	.	.	.
cord-022561-rv5j1201	2320	1	There	there	EX
cord-022561-rv5j1201	2320	2	is	be	VBZ
cord-022561-rv5j1201	2320	3	great	great	JJ
cord-022561-rv5j1201	2320	4	variation	variation	NN
cord-022561-rv5j1201	2320	5	in	in	IN
cord-022561-rv5j1201	2320	6	the	the	DT
cord-022561-rv5j1201	2320	7	clinical	clinical	JJ
cord-022561-rv5j1201	2320	8	manifestations	manifestation	NNS
cord-022561-rv5j1201	2320	9	and	and	CC
cord-022561-rv5j1201	2320	10	cytopathologic	cytopathologic	JJ
cord-022561-rv5j1201	2320	11	features	feature	NNS
cord-022561-rv5j1201	2320	12	of	of	IN
cord-022561-rv5j1201	2320	13	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2320	14	,	,	,
cord-022561-rv5j1201	2320	15	which	which	WDT
cord-022561-rv5j1201	2320	16	underlie	underlie	VBP
cord-022561-rv5j1201	2320	17	the	the	DT
cord-022561-rv5j1201	2320	18	importance	importance	NN
cord-022561-rv5j1201	2320	19	of	of	IN
cord-022561-rv5j1201	2320	20	classification	classification	NN
cord-022561-rv5j1201	2320	21	to	to	TO
cord-022561-rv5j1201	2320	22	better	better	RB
cord-022561-rv5j1201	2320	23	predict	predict	VB
cord-022561-rv5j1201	2320	24	the	the	DT
cord-022561-rv5j1201	2320	25	clinical	clinical	JJ
cord-022561-rv5j1201	2320	26	behavior	behavior	NN
cord-022561-rv5j1201	2320	27	and	and	CC
cord-022561-rv5j1201	2320	28	outcome	outcome	NN
cord-022561-rv5j1201	2320	29	.	.	.
cord-022561-rv5j1201	2321	1	An	an	DT
cord-022561-rv5j1201	2321	2	understanding	understanding	NN
cord-022561-rv5j1201	2321	3	of	of	IN
cord-022561-rv5j1201	2321	4	lymphocyte	lymphocyte	NN
cord-022561-rv5j1201	2321	5	maturation	maturation	NN
cord-022561-rv5j1201	2321	6	is	be	VBZ
cord-022561-rv5j1201	2321	7	crucial	crucial	JJ
cord-022561-rv5j1201	2321	8	,	,	,
cord-022561-rv5j1201	2321	9	because	because	IN
cord-022561-rv5j1201	2321	10	the	the	DT
cord-022561-rv5j1201	2321	11	WHO	WHO	NNP
cord-022561-rv5j1201	2321	12	classification	classification	NN
cord-022561-rv5j1201	2321	13	of	of	IN
cord-022561-rv5j1201	2321	14	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2321	15	postulates	postulate	VBZ
cord-022561-rv5j1201	2321	16	a	a	DT
cord-022561-rv5j1201	2321	17	normal	normal	JJ
cord-022561-rv5j1201	2321	18	cell	cell	NN
cord-022561-rv5j1201	2321	19	counterpart	counterpart	NN
cord-022561-rv5j1201	2321	20	for	for	IN
cord-022561-rv5j1201	2321	21	each	each	DT
cord-022561-rv5j1201	2321	22	type	type	NN
cord-022561-rv5j1201	2321	23	of	of	IN
cord-022561-rv5j1201	2321	24	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2321	25	(	(	-LRB-
cord-022561-rv5j1201	2321	26	when	when	WRB
cord-022561-rv5j1201	2321	27	possible	possible	JJ
cord-022561-rv5j1201	2321	28	)	)	-RRB-
cord-022561-rv5j1201	2321	29	.	.	.
cord-022561-rv5j1201	2322	1	In	in	IN
cord-022561-rv5j1201	2322	2	other	other	JJ
cord-022561-rv5j1201	2322	3	words	word	NNS
cord-022561-rv5j1201	2322	4	,	,	,
cord-022561-rv5j1201	2322	5	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2322	6	can	can	MD
cord-022561-rv5j1201	2322	7	arise	arise	VB
cord-022561-rv5j1201	2322	8	at	at	IN
cord-022561-rv5j1201	2322	9	any	any	DT
cord-022561-rv5j1201	2322	10	stage	stage	NN
cord-022561-rv5j1201	2322	11	in	in	IN
cord-022561-rv5j1201	2322	12	the	the	DT
cord-022561-rv5j1201	2322	13	development	development	NN
cord-022561-rv5j1201	2322	14	/	/	SYM
cord-022561-rv5j1201	2322	15	maturation	maturation	NN
cord-022561-rv5j1201	2322	16	of	of	IN
cord-022561-rv5j1201	2322	17	a	a	DT
cord-022561-rv5j1201	2322	18	lymphocyte	lymphocyte	NN
cord-022561-rv5j1201	2322	19	-	-	HYPH
cord-022561-rv5j1201	2322	20	from	from	IN
cord-022561-rv5j1201	2322	21	precursor	precursor	NN
cord-022561-rv5j1201	2322	22	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	2323	1	(	(	-LRB-
cord-022561-rv5j1201	2323	2	B	b	NN
cord-022561-rv5j1201	2323	3	or	or	CC
cord-022561-rv5j1201	2323	4	T	T	NNP
cord-022561-rv5j1201	2323	5	lymphoblasts	lymphoblast	NNS
cord-022561-rv5j1201	2323	6	)	)	-RRB-
cord-022561-rv5j1201	2323	7	to	to	TO
cord-022561-rv5j1201	2323	8	mature	mature	VB
cord-022561-rv5j1201	2323	9	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	2323	10	B	b	NN
cord-022561-rv5j1201	2323	11	and	and	CC
cord-022561-rv5j1201	2323	12	T	t	NN
cord-022561-rv5j1201	2323	13	,	,	,
cord-022561-rv5j1201	2323	14	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	2323	15	and	and	CC
cord-022561-rv5j1201	2323	16	NK	NK	NNP
cord-022561-rv5j1201	2323	17	cells	cell	NNS
cord-022561-rv5j1201	2323	18	(	(	-LRB-
cord-022561-rv5j1201	2323	19	Table	table	NN
cord-022561-rv5j1201	2323	20	13	13	CD
cord-022561-rv5j1201	2323	21	-7	-7	CD
cord-022561-rv5j1201	2323	22	and	and	CC
cord-022561-rv5j1201	2323	23	Box	Box	NNP
cord-022561-rv5j1201	2323	24	13	13	CD
cord-022561-rv5j1201	2323	25	-	-	SYM
cord-022561-rv5j1201	2323	26	11	11	CD
cord-022561-rv5j1201	2323	27	)	)	-RRB-
cord-022561-rv5j1201	2323	28	.	.	.
cord-022561-rv5j1201	2324	1	Pathologists	pathologist	NNS
cord-022561-rv5j1201	2324	2	use	use	VBP
cord-022561-rv5j1201	2324	3	gross	gross	JJ
cord-022561-rv5j1201	2324	4	features	feature	NNS
cord-022561-rv5j1201	2324	5	,	,	,
cord-022561-rv5j1201	2324	6	histomorphologic	histomorphologic	NNP
cord-022561-rv5j1201	2324	7	features	feature	NNS
cord-022561-rv5j1201	2324	8	,	,	,
cord-022561-rv5j1201	2324	9	immunophenotype	immunophenotype	NNP
cord-022561-rv5j1201	2324	10	(	(	-LRB-
cord-022561-rv5j1201	2324	11	B	B	NNP
cord-022561-rv5j1201	2324	12	or	or	CC
cord-022561-rv5j1201	2324	13	T	T	NNP
cord-022561-rv5j1201	2324	14	lymphocyte	lymphocyte	NN
cord-022561-rv5j1201	2324	15	)	)	-RRB-
cord-022561-rv5j1201	2324	16	,	,	,
cord-022561-rv5j1201	2324	17	and	and	CC
cord-022561-rv5j1201	2324	18	clinical	clinical	JJ
cord-022561-rv5j1201	2324	19	characteristics	characteristic	NNS
cord-022561-rv5j1201	2324	20	to	to	IN
cord-022561-rv5j1201	2324	21	Red	red	JJ
cord-022561-rv5j1201	2324	22	discoloration	discoloration	NN
cord-022561-rv5j1201	2324	23	is	be	VBZ
cord-022561-rv5j1201	2324	24	caused	cause	VBN
cord-022561-rv5j1201	2324	25	by	by	IN
cord-022561-rv5j1201	2324	26	(	(	-LRB-
cord-022561-rv5j1201	2324	27	1	1	CD
cord-022561-rv5j1201	2324	28	)	)	-RRB-
cord-022561-rv5j1201	2324	29	draining	drain	VBG
cord-022561-rv5j1201	2324	30	erythrocytes	erythrocyte	NNS
cord-022561-rv5j1201	2324	31	from	from	IN
cord-022561-rv5j1201	2324	32	hemorrhagic	hemorrhagic	JJ
cord-022561-rv5j1201	2324	33	or	or	CC
cord-022561-rv5j1201	2324	34	acutely	acutely	RB
cord-022561-rv5j1201	2324	35	inflamed	inflamed	JJ
cord-022561-rv5j1201	2324	36	areas	area	NNS
cord-022561-rv5j1201	2324	37	,	,	,
cord-022561-rv5j1201	2324	38	(	(	-LRB-
cord-022561-rv5j1201	2324	39	2	2	LS
cord-022561-rv5j1201	2324	40	)	)	-RRB-
cord-022561-rv5j1201	2324	41	acute	acute	JJ
cord-022561-rv5j1201	2324	42	lymphadenitis	lymphadenitis	NN
cord-022561-rv5j1201	2324	43	with	with	IN
cord-022561-rv5j1201	2324	44	hyperemia	hyperemia	NN
cord-022561-rv5j1201	2324	45	and/or	and/or	CC
cord-022561-rv5j1201	2324	46	hemorrhage	hemorrhage	NN
cord-022561-rv5j1201	2324	47	,	,	,
cord-022561-rv5j1201	2324	48	(	(	-LRB-
cord-022561-rv5j1201	2324	49	3	3	LS
cord-022561-rv5j1201	2324	50	)	)	-RRB-
cord-022561-rv5j1201	2324	51	acute	acute	JJ
cord-022561-rv5j1201	2324	52	septicemias	septicemias	NNP
cord-022561-rv5j1201	2324	53	with	with	IN
cord-022561-rv5j1201	2324	54	endotoxininduced	endotoxininduced	JJ
cord-022561-rv5j1201	2324	55	vasculitis	vasculitis	NN
cord-022561-rv5j1201	2324	56	or	or	CC
cord-022561-rv5j1201	2324	57	disseminated	disseminate	VBN
cord-022561-rv5j1201	2324	58	intravascular	intravascular	JJ
cord-022561-rv5j1201	2324	59	coagulation	coagulation	NN
cord-022561-rv5j1201	2324	60	,	,	,
cord-022561-rv5j1201	2324	61	and	and	CC
cord-022561-rv5j1201	2324	62	(	(	-LRB-
cord-022561-rv5j1201	2324	63	4	4	LS
cord-022561-rv5j1201	2324	64	)	)	-RRB-
cord-022561-rv5j1201	2324	65	dependent	dependent	JJ
cord-022561-rv5j1201	2324	66	areas	area	NNS
cord-022561-rv5j1201	2324	67	in	in	IN
cord-022561-rv5j1201	2324	68	postmortem	postmortem	JJ
cord-022561-rv5j1201	2324	69	hypostatic	hypostatic	NN
cord-022561-rv5j1201	2324	70	congestion	congestion	NN
cord-022561-rv5j1201	2324	71	.	.	.
cord-022561-rv5j1201	2325	1	Blood	blood	NN
cord-022561-rv5j1201	2325	2	in	in	IN
cord-022561-rv5j1201	2325	3	pig	pig	NN
cord-022561-rv5j1201	2325	4	lymph	lymph	NN
cord-022561-rv5j1201	2325	5	nodes	node	NNS
cord-022561-rv5j1201	2325	6	is	be	VBZ
cord-022561-rv5j1201	2325	7	especially	especially	RB
cord-022561-rv5j1201	2325	8	obvious	obvious	JJ
cord-022561-rv5j1201	2325	9	due	due	IN
cord-022561-rv5j1201	2325	10	to	to	IN
cord-022561-rv5j1201	2325	11	the	the	DT
cord-022561-rv5j1201	2325	12	inverse	inverse	JJ
cord-022561-rv5j1201	2325	13	anatomy	anatomy	NN
cord-022561-rv5j1201	2325	14	(	(	-LRB-
cord-022561-rv5j1201	2325	15	the	the	DT
cord-022561-rv5j1201	2325	16	equivalent	equivalent	NN
cord-022561-rv5j1201	2325	17	of	of	IN
cord-022561-rv5j1201	2325	18	the	the	DT
cord-022561-rv5j1201	2325	19	medullary	medullary	JJ
cord-022561-rv5j1201	2325	20	sinuses	sinus	NNS
cord-022561-rv5j1201	2325	21	are	be	VBP
cord-022561-rv5j1201	2325	22	subcapsular	subcapsular	JJ
cord-022561-rv5j1201	2325	23	and	and	CC
cord-022561-rv5j1201	2325	24	thus	thus	RB
cord-022561-rv5j1201	2325	25	readily	readily	RB
cord-022561-rv5j1201	2325	26	visible	visible	JJ
cord-022561-rv5j1201	2325	27	in	in	IN
cord-022561-rv5j1201	2325	28	the	the	DT
cord-022561-rv5j1201	2325	29	unsectioned	unsectioned	JJ
cord-022561-rv5j1201	2325	30	node	node	NN
cord-022561-rv5j1201	2325	31	)	)	-RRB-
cord-022561-rv5j1201	2325	32	.	.	.
cord-022561-rv5j1201	2326	1	Initially	initially	RB
cord-022561-rv5j1201	2326	2	erythrocytes	erythrocyte	NNS
cord-022561-rv5j1201	2326	3	fill	fill	VBP
cord-022561-rv5j1201	2326	4	trabecular	trabecular	JJ
cord-022561-rv5j1201	2326	5	and	and	CC
cord-022561-rv5j1201	2326	6	medullary	medullary	JJ
cord-022561-rv5j1201	2326	7	sinuses	sinus	NNS
cord-022561-rv5j1201	2326	8	and	and	CC
cord-022561-rv5j1201	2326	9	then	then	RB
cord-022561-rv5j1201	2326	10	rapidly	rapidly	RB
cord-022561-rv5j1201	2326	11	undergo	undergo	VBP
cord-022561-rv5j1201	2326	12	erythrophagocytosis	erythrophagocytosis	NN
cord-022561-rv5j1201	2326	13	by	by	IN
cord-022561-rv5j1201	2326	14	proliferating	proliferate	VBG
cord-022561-rv5j1201	2326	15	sinus	sinus	NN
cord-022561-rv5j1201	2326	16	macrophages	macrophage	NNS
cord-022561-rv5j1201	2326	17	.	.	.
cord-022561-rv5j1201	2327	1	Hemosiderin	Hemosiderin	NNP
cord-022561-rv5j1201	2327	2	deposition	deposition	NN
cord-022561-rv5j1201	2327	3	occurs	occur	VBZ
cord-022561-rv5j1201	2327	4	within	within	IN
cord-022561-rv5j1201	2327	5	7	7	CD
cord-022561-rv5j1201	2327	6	to	to	TO
cord-022561-rv5j1201	2327	7	10	10	CD
cord-022561-rv5j1201	2327	8	days	day	NNS
cord-022561-rv5j1201	2327	9	in	in	IN
cord-022561-rv5j1201	2327	10	these	these	DT
cord-022561-rv5j1201	2327	11	macrophages	macrophage	NNS
cord-022561-rv5j1201	2327	12	,	,	,
cord-022561-rv5j1201	2327	13	imparting	impart	VBG
cord-022561-rv5j1201	2327	14	a	a	DT
cord-022561-rv5j1201	2327	15	brown	brown	JJ
cord-022561-rv5j1201	2327	16	discoloration	discoloration	NN
cord-022561-rv5j1201	2327	17	of	of	IN
cord-022561-rv5j1201	2327	18	the	the	DT
cord-022561-rv5j1201	2327	19	node	node	NN
cord-022561-rv5j1201	2327	20	.	.	.
cord-022561-rv5j1201	2328	1	Black	black	JJ
cord-022561-rv5j1201	2328	2	discoloration	discoloration	NN
cord-022561-rv5j1201	2328	3	is	be	VBZ
cord-022561-rv5j1201	2328	4	often	often	RB
cord-022561-rv5j1201	2328	5	present	present	JJ
cord-022561-rv5j1201	2328	6	in	in	IN
cord-022561-rv5j1201	2328	7	the	the	DT
cord-022561-rv5j1201	2328	8	tracheobronchial	tracheobronchial	JJ
cord-022561-rv5j1201	2328	9	lymph	lymph	NN
cord-022561-rv5j1201	2328	10	nodes	node	NNS
cord-022561-rv5j1201	2328	11	due	due	JJ
cord-022561-rv5j1201	2328	12	to	to	IN
cord-022561-rv5j1201	2328	13	draining	drain	VBG
cord-022561-rv5j1201	2328	14	of	of	IN
cord-022561-rv5j1201	2328	15	carbon	carbon	NN
cord-022561-rv5j1201	2328	16	pigment	pigment	NN
cord-022561-rv5j1201	2328	17	(	(	-LRB-
cord-022561-rv5j1201	2328	18	pulmonary	pulmonary	JJ
cord-022561-rv5j1201	2328	19	anthracosis	anthracosis	NN
cord-022561-rv5j1201	2328	20	,	,	,
cord-022561-rv5j1201	2328	21	see	see	VB
cord-022561-rv5j1201	2328	22	Chapter	chapter	NN
cord-022561-rv5j1201	2328	23	9	9	CD
cord-022561-rv5j1201	2328	24	)	)	-RRB-
cord-022561-rv5j1201	2328	25	.	.	.
cord-022561-rv5j1201	2329	1	Black	black	JJ
cord-022561-rv5j1201	2329	2	ink	ink	NN
cord-022561-rv5j1201	2329	3	from	from	IN
cord-022561-rv5j1201	2329	4	skin	skin	NN
cord-022561-rv5j1201	2329	5	tattoos	tattoo	NNS
cord-022561-rv5j1201	2329	6	will	will	MD
cord-022561-rv5j1201	2329	7	drain	drain	VB
cord-022561-rv5j1201	2329	8	to	to	IN
cord-022561-rv5j1201	2329	9	the	the	DT
cord-022561-rv5j1201	2329	10	regional	regional	JJ
cord-022561-rv5j1201	2329	11	lymph	lymph	NN
cord-022561-rv5j1201	2329	12	node	node	NN
cord-022561-rv5j1201	2329	13	.	.	.
cord-022561-rv5j1201	2330	1	These	these	DT
cord-022561-rv5j1201	2330	2	pigments	pigment	NNS
cord-022561-rv5j1201	2330	3	are	be	VBP
cord-022561-rv5j1201	2330	4	usually	usually	RB
cord-022561-rv5j1201	2330	5	noted	note	VBN
cord-022561-rv5j1201	2330	6	within	within	IN
cord-022561-rv5j1201	2330	7	the	the	DT
cord-022561-rv5j1201	2330	8	medullary	medullary	JJ
cord-022561-rv5j1201	2330	9	sinus	sinus	NN
cord-022561-rv5j1201	2330	10	macrophages	macrophage	NNS
cord-022561-rv5j1201	2330	11	.	.	.
cord-022561-rv5j1201	2331	1	Brown	brown	JJ
cord-022561-rv5j1201	2331	2	discoloration	discoloration	NN
cord-022561-rv5j1201	2331	3	may	may	MD
cord-022561-rv5j1201	2331	4	be	be	VB
cord-022561-rv5j1201	2331	5	due	due	JJ
cord-022561-rv5j1201	2331	6	to	to	IN
cord-022561-rv5j1201	2331	7	melanin	melanin	NN
cord-022561-rv5j1201	2331	8	,	,	,
cord-022561-rv5j1201	2331	9	parasitic	parasitic	JJ
cord-022561-rv5j1201	2331	10	hematin	hematin	NN
cord-022561-rv5j1201	2331	11	,	,	,
cord-022561-rv5j1201	2331	12	or	or	CC
cord-022561-rv5j1201	2331	13	hemosiderin	hemosiderin	NNP
cord-022561-rv5j1201	2331	14	.	.	.
cord-022561-rv5j1201	2332	1	Melanin	melanin	NN
cord-022561-rv5j1201	2332	2	pigment	pigment	NN
cord-022561-rv5j1201	2332	3	is	be	VBZ
cord-022561-rv5j1201	2332	4	seen	see	VBN
cord-022561-rv5j1201	2332	5	in	in	IN
cord-022561-rv5j1201	2332	6	animals	animal	NNS
cord-022561-rv5j1201	2332	7	with	with	IN
cord-022561-rv5j1201	2332	8	chronic	chronic	JJ
cord-022561-rv5j1201	2332	9	dermatitis	dermatitis	NN
cord-022561-rv5j1201	2332	10	when	when	WRB
cord-022561-rv5j1201	2332	11	melanocytes	melanocyte	NNS
cord-022561-rv5j1201	2332	12	are	be	VBP
cord-022561-rv5j1201	2332	13	damaged	damage	VBN
cord-022561-rv5j1201	2332	14	and	and	CC
cord-022561-rv5j1201	2332	15	their	-PRON-	PRP$
cord-022561-rv5j1201	2332	16	pigment	pigment	NN
cord-022561-rv5j1201	2332	17	is	be	VBZ
cord-022561-rv5j1201	2332	18	released	release	VBN
cord-022561-rv5j1201	2332	19	into	into	IN
cord-022561-rv5j1201	2332	20	the	the	DT
cord-022561-rv5j1201	2332	21	dermis	dermis	NN
cord-022561-rv5j1201	2332	22	and	and	CC
cord-022561-rv5j1201	2332	23	phagocytized	phagocytize	VBN
cord-022561-rv5j1201	2332	24	by	by	IN
cord-022561-rv5j1201	2332	25	melanomacrophages	melanomacrophage	NNS
cord-022561-rv5j1201	2332	26	(	(	-LRB-
cord-022561-rv5j1201	2332	27	pigmentary	pigmentary	NNP
cord-022561-rv5j1201	2332	28	incontinence	incontinence	NN
cord-022561-rv5j1201	2332	29	)	)	-RRB-
cord-022561-rv5j1201	2332	30	and	and	CC
cord-022561-rv5j1201	2332	31	drained	drain	VBN
cord-022561-rv5j1201	2332	32	to	to	IN
cord-022561-rv5j1201	2332	33	the	the	DT
cord-022561-rv5j1201	2332	34	regional	regional	JJ
cord-022561-rv5j1201	2332	35	lymph	lymph	NN
cord-022561-rv5j1201	2332	36	node	node	NN
cord-022561-rv5j1201	2332	37	.	.	.
cord-022561-rv5j1201	2333	1	The	the	DT
cord-022561-rv5j1201	2333	2	mandibular	mandibular	JJ
cord-022561-rv5j1201	2333	3	lymph	lymph	NN
cord-022561-rv5j1201	2333	4	nodes	node	NNS
cord-022561-rv5j1201	2333	5	often	often	RB
cord-022561-rv5j1201	2333	6	contain	contain	VBP
cord-022561-rv5j1201	2333	7	numerous	numerous	JJ
cord-022561-rv5j1201	2333	8	melanomacrophages	melanomacrophage	NNS
cord-022561-rv5j1201	2333	9	in	in	IN
cord-022561-rv5j1201	2333	10	animals	animal	NNS
cord-022561-rv5j1201	2333	11	with	with	IN
cord-022561-rv5j1201	2333	12	heavily	heavily	RB
cord-022561-rv5j1201	2333	13	pigmented	pigmented	JJ
cord-022561-rv5j1201	2333	14	oral	oral	JJ
cord-022561-rv5j1201	2333	15	mucosa	mucosa	NN
cord-022561-rv5j1201	2333	16	,	,	,
cord-022561-rv5j1201	2333	17	presumably	presumably	RB
cord-022561-rv5j1201	2333	18	due	due	JJ
cord-022561-rv5j1201	2333	19	to	to	IN
cord-022561-rv5j1201	2333	20	chronic	chronic	JJ
cord-022561-rv5j1201	2333	21	low	low	JJ
cord-022561-rv5j1201	2333	22	levels	level	NNS
cord-022561-rv5j1201	2333	23	of	of	IN
cord-022561-rv5j1201	2333	24	inflammation	inflammation	NN
cord-022561-rv5j1201	2333	25	.	.	.
cord-022561-rv5j1201	2334	1	This	this	DT
cord-022561-rv5j1201	2334	2	must	must	MD
cord-022561-rv5j1201	2334	3	be	be	VB
cord-022561-rv5j1201	2334	4	distinguished	distinguish	VBN
cord-022561-rv5j1201	2334	5	from	from	IN
cord-022561-rv5j1201	2334	6	metastatic	metastatic	JJ
cord-022561-rv5j1201	2334	7	malignant	malignant	JJ
cord-022561-rv5j1201	2334	8	melanomas	melanoma	NNS
cord-022561-rv5j1201	2334	9	.	.	.
cord-022561-rv5j1201	2335	1	Lymph	lymph	NN
cord-022561-rv5j1201	2335	2	nodes	node	NNS
cord-022561-rv5j1201	2335	3	draining	drain	VBG
cord-022561-rv5j1201	2335	4	areas	area	NNS
cord-022561-rv5j1201	2335	5	of	of	IN
cord-022561-rv5j1201	2335	6	congenital	congenital	JJ
cord-022561-rv5j1201	2335	7	melanosis	melanosis	NN
cord-022561-rv5j1201	2335	8	may	may	MD
cord-022561-rv5j1201	2335	9	have	have	VB
cord-022561-rv5j1201	2335	10	melanin	melanin	NN
cord-022561-rv5j1201	2335	11	deposits	deposit	NNS
cord-022561-rv5j1201	2335	12	.	.	.
cord-022561-rv5j1201	2336	1	Parasitic	parasitic	JJ
cord-022561-rv5j1201	2336	2	hematin	hematin	NN
cord-022561-rv5j1201	2336	3	pigment	pigment	NN
cord-022561-rv5j1201	2336	4	is	be	VBZ
cord-022561-rv5j1201	2336	5	produced	produce	VBN
cord-022561-rv5j1201	2336	6	by	by	IN
cord-022561-rv5j1201	2336	7	Fascioloides	Fascioloides	NNP
cord-022561-rv5j1201	2336	8	magna	magna	NN
cord-022561-rv5j1201	2336	9	(	(	-LRB-
cord-022561-rv5j1201	2336	10	cattle	cattle	NNS
cord-022561-rv5j1201	2336	11	)	)	-RRB-
cord-022561-rv5j1201	2336	12	and	and	CC
cord-022561-rv5j1201	2336	13	Fasciola	Fasciola	NNP
cord-022561-rv5j1201	2336	14	hepatica	hepatica	NNP
cord-022561-rv5j1201	2336	15	(	(	-LRB-
cord-022561-rv5j1201	2336	16	sheep	sheep	NNP
cord-022561-rv5j1201	2336	17	)	)	-RRB-
cord-022561-rv5j1201	2336	18	in	in	IN
cord-022561-rv5j1201	2336	19	the	the	DT
cord-022561-rv5j1201	2336	20	liver	liver	NN
cord-022561-rv5j1201	2336	21	and	and	CC
cord-022561-rv5j1201	2336	22	then	then	RB
cord-022561-rv5j1201	2336	23	transported	transport	VBN
cord-022561-rv5j1201	2336	24	via	via	IN
cord-022561-rv5j1201	2336	25	the	the	DT
cord-022561-rv5j1201	2336	26	lymphatic	lymphatic	JJ
cord-022561-rv5j1201	2336	27	vessels	vessel	NNS
cord-022561-rv5j1201	2336	28	to	to	IN
cord-022561-rv5j1201	2336	29	the	the	DT
cord-022561-rv5j1201	2336	30	hepatic	hepatic	JJ
cord-022561-rv5j1201	2336	31	lymph	lymph	NN
cord-022561-rv5j1201	2336	32	nodes	node	NNS
cord-022561-rv5j1201	2336	33	.	.	.
cord-022561-rv5j1201	2337	1	Hemosiderin	Hemosiderin	NNP
cord-022561-rv5j1201	2337	2	,	,	,
cord-022561-rv5j1201	2337	3	an	an	DT
cord-022561-rv5j1201	2337	4	erythrocyte	erythrocyte	NN
cord-022561-rv5j1201	2337	5	breakdown	breakdown	NN
cord-022561-rv5j1201	2337	6	product	product	NN
cord-022561-rv5j1201	2337	7	,	,	,
cord-022561-rv5j1201	2337	8	may	may	MD
cord-022561-rv5j1201	2337	9	form	form	VB
cord-022561-rv5j1201	2337	10	in	in	IN
cord-022561-rv5j1201	2337	11	a	a	DT
cord-022561-rv5j1201	2337	12	hemorrhagic	hemorrhagic	JJ
cord-022561-rv5j1201	2337	13	node	node	NN
cord-022561-rv5j1201	2337	14	or	or	CC
cord-022561-rv5j1201	2337	15	arrive	arrive	VBP
cord-022561-rv5j1201	2337	16	in	in	IN
cord-022561-rv5j1201	2337	17	hemosiderophages	hemosiderophage	NNS
cord-022561-rv5j1201	2337	18	draining	drain	VBG
cord-022561-rv5j1201	2337	19	from	from	IN
cord-022561-rv5j1201	2337	20	congested	congested	JJ
cord-022561-rv5j1201	2337	21	,	,	,
cord-022561-rv5j1201	2337	22	hemorrhagic	hemorrhagic	JJ
cord-022561-rv5j1201	2337	23	,	,	,
cord-022561-rv5j1201	2337	24	or	or	CC
cord-022561-rv5j1201	2337	25	inflamed	inflamed	JJ
cord-022561-rv5j1201	2337	26	areas	area	NNS
cord-022561-rv5j1201	2337	27	.	.	.
cord-022561-rv5j1201	2338	1	Drainage	drainage	NN
cord-022561-rv5j1201	2338	2	of	of	IN
cord-022561-rv5j1201	2338	3	iron	iron	NN
cord-022561-rv5j1201	2338	4	dextran	dextran	NN
cord-022561-rv5j1201	2338	5	from	from	IN
cord-022561-rv5j1201	2338	6	an	an	DT
cord-022561-rv5j1201	2338	7	intramuscular	intramuscular	JJ
cord-022561-rv5j1201	2338	8	injection	injection	NN
cord-022561-rv5j1201	2338	9	may	may	MD
cord-022561-rv5j1201	2338	10	also	also	RB
cord-022561-rv5j1201	2338	11	cause	cause	VB
cord-022561-rv5j1201	2338	12	hemosiderin	hemosiderin	NNP
cord-022561-rv5j1201	2338	13	pigment	pigment	NN
cord-022561-rv5j1201	2338	14	accumulation	accumulation	NN
cord-022561-rv5j1201	2338	15	within	within	IN
cord-022561-rv5j1201	2338	16	the	the	DT
cord-022561-rv5j1201	2338	17	draining	drain	VBG
cord-022561-rv5j1201	2338	18	lymph	lymph	NN
cord-022561-rv5j1201	2338	19	node	node	NN
cord-022561-rv5j1201	2338	20	.	.	.
cord-022561-rv5j1201	2339	1	Green	green	JJ
cord-022561-rv5j1201	2339	2	discoloration	discoloration	NN
cord-022561-rv5j1201	2339	3	is	be	VBZ
cord-022561-rv5j1201	2339	4	rare	rare	JJ
cord-022561-rv5j1201	2339	5	and	and	CC
cord-022561-rv5j1201	2339	6	may	may	MD
cord-022561-rv5j1201	2339	7	be	be	VB
cord-022561-rv5j1201	2339	8	caused	cause	VBN
cord-022561-rv5j1201	2339	9	by	by	IN
cord-022561-rv5j1201	2339	10	green	green	JJ
cord-022561-rv5j1201	2339	11	tattoo	tattoo	NN
cord-022561-rv5j1201	2339	12	ink	ink	NN
cord-022561-rv5j1201	2339	13	(	(	-LRB-
cord-022561-rv5j1201	2339	14	often	often	RB
cord-022561-rv5j1201	2339	15	used	use	VBN
cord-022561-rv5j1201	2339	16	in	in	IN
cord-022561-rv5j1201	2339	17	black	black	JJ
cord-022561-rv5j1201	2339	18	animals	animal	NNS
cord-022561-rv5j1201	2339	19	)	)	-RRB-
cord-022561-rv5j1201	2339	20	;	;	:
cord-022561-rv5j1201	2339	21	ingestion	ingestion	NN
cord-022561-rv5j1201	2339	22	of	of	IN
cord-022561-rv5j1201	2339	23	blue	blue	JJ
cord-022561-rv5j1201	2339	24	-	-	HYPH
cord-022561-rv5j1201	2339	25	green	green	JJ
cord-022561-rv5j1201	2339	26	algae	algae	NN
cord-022561-rv5j1201	2339	27	,	,	,
cord-022561-rv5j1201	2339	28	which	which	WDT
cord-022561-rv5j1201	2339	29	drain	drain	VBP
cord-022561-rv5j1201	2339	30	to	to	IN
cord-022561-rv5j1201	2339	31	mesenteric	mesenteric	JJ
cord-022561-rv5j1201	2339	32	lymph	lymph	NN
cord-022561-rv5j1201	2339	33	nodes	node	NNS
cord-022561-rv5j1201	2339	34	;	;	,
cord-022561-rv5j1201	2339	35	massive	massive	JJ
cord-022561-rv5j1201	2339	36	eosinophilic	eosinophilic	JJ
cord-022561-rv5j1201	2339	37	inflammation	inflammation	NN
cord-022561-rv5j1201	2339	38	;	;	:
cord-022561-rv5j1201	2339	39	and	and	CC
cord-022561-rv5j1201	2339	40	in	in	IN
cord-022561-rv5j1201	2339	41	mutant	mutant	JJ
cord-022561-rv5j1201	2339	42	Corriedale	corriedale	JJ
cord-022561-rv5j1201	2339	43	sheep	sheep	NN
cord-022561-rv5j1201	2339	44	,	,	,
cord-022561-rv5j1201	2339	45	which	which	WDT
cord-022561-rv5j1201	2339	46	have	have	VBP
cord-022561-rv5j1201	2339	47	a	a	DT
cord-022561-rv5j1201	2339	48	genetic	genetic	JJ
cord-022561-rv5j1201	2339	49	defect	defect	NN
cord-022561-rv5j1201	2339	50	that	that	WDT
cord-022561-rv5j1201	2339	51	results	result	VBZ
cord-022561-rv5j1201	2339	52	in	in	IN
cord-022561-rv5j1201	2339	53	a	a	DT
cord-022561-rv5j1201	2339	54	deficiency	deficiency	NN
cord-022561-rv5j1201	2339	55	in	in	IN
cord-022561-rv5j1201	2339	56	the	the	DT
cord-022561-rv5j1201	2339	57	excretion	excretion	NN
cord-022561-rv5j1201	2339	58	of	of	IN
cord-022561-rv5j1201	2339	59	bilirubin	bilirubin	NN
cord-022561-rv5j1201	2339	60	and	and	CC
cord-022561-rv5j1201	2339	61	phylloerythrin	phylloerythrin	NN
cord-022561-rv5j1201	2339	62	by	by	IN
cord-022561-rv5j1201	2339	63	the	the	DT
cord-022561-rv5j1201	2339	64	liver	liver	NN
cord-022561-rv5j1201	2339	65	.	.	.
cord-022561-rv5j1201	2340	1	The	the	DT
cord-022561-rv5j1201	2340	2	phylloerythrin	phylloerythrin	NN
cord-022561-rv5j1201	2340	3	or	or	CC
cord-022561-rv5j1201	2340	4	a	a	DT
cord-022561-rv5j1201	2340	5	metabolite	metabolite	NN
cord-022561-rv5j1201	2340	6	stains	stain	VBZ
cord-022561-rv5j1201	2340	7	all	all	PDT
cord-022561-rv5j1201	2340	8	the	the	DT
cord-022561-rv5j1201	2340	9	tissues	tissue	NNS
cord-022561-rv5j1201	2340	10	of	of	IN
cord-022561-rv5j1201	2340	11	the	the	DT
cord-022561-rv5j1201	2340	12	body	body	NN
cord-022561-rv5j1201	2340	13	a	a	DT
cord-022561-rv5j1201	2340	14	dark	dark	JJ
cord-022561-rv5j1201	2340	15	green	green	NN
cord-022561-rv5j1201	2340	16	,	,	,
cord-022561-rv5j1201	2340	17	except	except	IN
cord-022561-rv5j1201	2340	18	for	for	IN
cord-022561-rv5j1201	2340	19	the	the	DT
cord-022561-rv5j1201	2340	20	brain	brain	NN
cord-022561-rv5j1201	2340	21	and	and	CC
cord-022561-rv5j1201	2340	22	spinal	spinal	JJ
cord-022561-rv5j1201	2340	23	cord	cord	NN
cord-022561-rv5j1201	2340	24	,	,	,
cord-022561-rv5j1201	2340	25	which	which	WDT
cord-022561-rv5j1201	2340	26	are	be	VBP
cord-022561-rv5j1201	2340	27	protected	protect	VBN
cord-022561-rv5j1201	2340	28	by	by	IN
cord-022561-rv5j1201	2340	29	the	the	DT
cord-022561-rv5j1201	2340	30	blood	blood	NN
cord-022561-rv5j1201	2340	31	-	-	HYPH
cord-022561-rv5j1201	2340	32	brain	brain	NN
cord-022561-rv5j1201	2340	33	barrier	barrier	NN
cord-022561-rv5j1201	2340	34	.	.	.
cord-022561-rv5j1201	2341	1	Miscellaneous	miscellaneous	JJ
cord-022561-rv5j1201	2341	2	discolorations	discoloration	NNS
cord-022561-rv5j1201	2341	3	of	of	IN
cord-022561-rv5j1201	2341	4	lymph	lymph	NN
cord-022561-rv5j1201	2341	5	nodes	node	NNS
cord-022561-rv5j1201	2341	6	may	may	MD
cord-022561-rv5j1201	2341	7	be	be	VB
cord-022561-rv5j1201	2341	8	seen	see	VBN
cord-022561-rv5j1201	2341	9	with	with	IN
cord-022561-rv5j1201	2341	10	intravenously	intravenously	RB
cord-022561-rv5j1201	2341	11	injected	inject	VBN
cord-022561-rv5j1201	2341	12	dyes	dye	NNS
cord-022561-rv5j1201	2341	13	(	(	-LRB-
cord-022561-rv5j1201	2341	14	e.g.	e.g.	RB
cord-022561-rv5j1201	2341	15	,	,	,
cord-022561-rv5j1201	2341	16	methylene	methylene	NN
cord-022561-rv5j1201	2341	17	blue	blue	NN
cord-022561-rv5j1201	2341	18	or	or	CC
cord-022561-rv5j1201	2341	19	trypan	trypan	NNP
cord-022561-rv5j1201	2341	20	blue	blue	NNP
cord-022561-rv5j1201	2341	21	)	)	-RRB-
cord-022561-rv5j1201	2341	22	or	or	CC
cord-022561-rv5j1201	2341	23	subcutaneous	subcutaneous	JJ
cord-022561-rv5j1201	2341	24	drug	drug	NN
cord-022561-rv5j1201	2341	25	injections	injection	NNS
cord-022561-rv5j1201	2341	26	.	.	.
cord-022561-rv5j1201	2342	1	Lymph	lymph	NN
cord-022561-rv5j1201	2342	2	nodes	node	NNS
cord-022561-rv5j1201	2342	3	may	may	MD
cord-022561-rv5j1201	2342	4	be	be	VB
cord-022561-rv5j1201	2342	5	yellow	yellow	JJ
cord-022561-rv5j1201	2342	6	in	in	IN
cord-022561-rv5j1201	2342	7	severely	severely	RB
cord-022561-rv5j1201	2342	8	icteric	icteric	JJ
cord-022561-rv5j1201	2342	9	patients	patient	NNS
cord-022561-rv5j1201	2342	10	.	.	.
cord-022561-rv5j1201	2343	1	The	the	DT
cord-022561-rv5j1201	2343	2	pigmented	pigmented	JJ
cord-022561-rv5j1201	2343	3	strain	strain	NN
cord-022561-rv5j1201	2343	4	of	of	IN
cord-022561-rv5j1201	2343	5	MAP	map	NN
cord-022561-rv5j1201	2343	6	(	(	-LRB-
cord-022561-rv5j1201	2343	7	Johne	Johne	NNP
cord-022561-rv5j1201	2343	8	's	's	POS
cord-022561-rv5j1201	2343	9	disease	disease	NN
cord-022561-rv5j1201	2343	10	)	)	-RRB-
cord-022561-rv5j1201	2343	11	may	may	MD
cord-022561-rv5j1201	2343	12	impart	impart	VB
cord-022561-rv5j1201	2343	13	an	an	DT
cord-022561-rv5j1201	2343	14	orange	orange	JJ
cord-022561-rv5j1201	2343	15	discoloration	discoloration	NN
cord-022561-rv5j1201	2343	16	in	in	IN
cord-022561-rv5j1201	2343	17	the	the	DT
cord-022561-rv5j1201	2343	18	mesenteric	mesenteric	JJ
cord-022561-rv5j1201	2343	19	lymph	lymph	NN
cord-022561-rv5j1201	2343	20	nodes	node	NNS
cord-022561-rv5j1201	2343	21	of	of	IN
cord-022561-rv5j1201	2343	22	sheep	sheep	NNS
cord-022561-rv5j1201	2343	23	.	.	.
cord-022561-rv5j1201	2344	1	Inclusion	inclusion	NN
cord-022561-rv5j1201	2344	2	Bodies	body	NNS
cord-022561-rv5j1201	2344	3	.	.	.
cord-022561-rv5j1201	2345	1	Many	many	JJ
cord-022561-rv5j1201	2345	2	viruses	virus	NNS
cord-022561-rv5j1201	2345	3	produce	produce	VBP
cord-022561-rv5j1201	2345	4	inclusion	inclusion	NN
cord-022561-rv5j1201	2345	5	bodies	body	NNS
cord-022561-rv5j1201	2345	6	,	,	,
cord-022561-rv5j1201	2345	7	and	and	CC
cord-022561-rv5j1201	2345	8	some	some	DT
cord-022561-rv5j1201	2345	9	of	of	IN
cord-022561-rv5j1201	2345	10	these	these	DT
cord-022561-rv5j1201	2345	11	occur	occur	VBP
cord-022561-rv5j1201	2345	12	in	in	IN
cord-022561-rv5j1201	2345	13	lymph	lymph	NN
cord-022561-rv5j1201	2345	14	nodes	node	NNS
cord-022561-rv5j1201	2345	15	.	.	.
cord-022561-rv5j1201	2346	1	These	these	DT
cord-022561-rv5j1201	2346	2	viruses	virus	NNS
cord-022561-rv5j1201	2346	3	include	include	VBP
cord-022561-rv5j1201	2346	4	EHV-1	EHV-1	NNPS
cord-022561-rv5j1201	2346	5	in	in	IN
cord-022561-rv5j1201	2346	6	horses	horse	NNS
cord-022561-rv5j1201	2346	7	,	,	,
cord-022561-rv5j1201	2346	8	bovine	bovine	JJ
cord-022561-rv5j1201	2346	9	adenovirus	adenovirus	NN
cord-022561-rv5j1201	2346	10	,	,	,
cord-022561-rv5j1201	2346	11	cytomegalic	cytomegalic	NN
cord-022561-rv5j1201	2346	12	virus	virus	NN
cord-022561-rv5j1201	2346	13	in	in	IN
cord-022561-rv5j1201	2346	14	inclusion	inclusion	NN
cord-022561-rv5j1201	2346	15	body	body	NN
cord-022561-rv5j1201	2346	16	rhinitis	rhinitis	NN
cord-022561-rv5j1201	2346	17	and	and	CC
cord-022561-rv5j1201	2346	18	PCV2	PCV2	NNP
cord-022561-rv5j1201	2346	19	,	,	,
cord-022561-rv5j1201	2346	20	herpesvirus	herpesvirus	NN
cord-022561-rv5j1201	2346	21	of	of	IN
cord-022561-rv5j1201	2346	22	pseudorabies	pseudorabie	NNS
cord-022561-rv5j1201	2346	23	in	in	IN
cord-022561-rv5j1201	2346	24	pigs	pig	NNS
cord-022561-rv5j1201	2346	25	,	,	,
cord-022561-rv5j1201	2346	26	and	and	CC
cord-022561-rv5j1201	2346	27	rarely	rarely	RB
cord-022561-rv5j1201	2346	28	parvovirus	parvovirus	NN
cord-022561-rv5j1201	2346	29	in	in	IN
cord-022561-rv5j1201	2346	30	dogs	dog	NNS
cord-022561-rv5j1201	2346	31	and	and	CC
cord-022561-rv5j1201	2346	32	cats	cat	NNS
cord-022561-rv5j1201	2346	33	.	.	.
cord-022561-rv5j1201	2347	1	Emphysema	emphysema	NN
cord-022561-rv5j1201	2347	2	.	.	.
cord-022561-rv5j1201	2348	1	Emphysema	emphysema	NN
cord-022561-rv5j1201	2348	2	in	in	IN
cord-022561-rv5j1201	2348	3	lymph	lymph	NN
cord-022561-rv5j1201	2348	4	nodes	node	NNS
cord-022561-rv5j1201	2348	5	is	be	VBZ
cord-022561-rv5j1201	2348	6	a	a	DT
cord-022561-rv5j1201	2348	7	consequence	consequence	NN
cord-022561-rv5j1201	2348	8	of	of	IN
cord-022561-rv5j1201	2348	9	emphysema	emphysema	NN
cord-022561-rv5j1201	2348	10	in	in	IN
cord-022561-rv5j1201	2348	11	their	-PRON-	PRP$
cord-022561-rv5j1201	2348	12	drainage	drainage	NN
cord-022561-rv5j1201	2348	13	fields	field	NNS
cord-022561-rv5j1201	2348	14	and	and	CC
cord-022561-rv5j1201	2348	15	is	be	VBZ
cord-022561-rv5j1201	2348	16	seen	see	VBN
cord-022561-rv5j1201	2348	17	most	most	RBS
cord-022561-rv5j1201	2348	18	frequently	frequently	RB
cord-022561-rv5j1201	2348	19	in	in	IN
cord-022561-rv5j1201	2348	20	tracheobronchial	tracheobronchial	JJ
cord-022561-rv5j1201	2348	21	lymph	lymph	NN
cord-022561-rv5j1201	2348	22	nodes	node	NNS
cord-022561-rv5j1201	2348	23	in	in	IN
cord-022561-rv5j1201	2348	24	bovine	bovine	JJ
cord-022561-rv5j1201	2348	25	interstitial	interstitial	JJ
cord-022561-rv5j1201	2348	26	emphysema	emphysema	NN
cord-022561-rv5j1201	2348	27	and	and	CC
cord-022561-rv5j1201	2348	28	in	in	IN
cord-022561-rv5j1201	2348	29	porcine	porcine	JJ
cord-022561-rv5j1201	2348	30	mesenteric	mesenteric	JJ
cord-022561-rv5j1201	2348	31	lymph	lymph	NN
cord-022561-rv5j1201	2348	32	nodes	node	NNS
cord-022561-rv5j1201	2348	33	in	in	IN
cord-022561-rv5j1201	2348	34	intestinal	intestinal	JJ
cord-022561-rv5j1201	2348	35	emphysema	emphysema	NN
cord-022561-rv5j1201	2348	36	(	(	-LRB-
cord-022561-rv5j1201	2348	37	see	see	VB
cord-022561-rv5j1201	2348	38	Chapter	Chapter	NNP
cord-022561-rv5j1201	2348	39	7	7	CD
cord-022561-rv5j1201	2348	40	)	)	-RRB-
cord-022561-rv5j1201	2348	41	.	.	.
cord-022561-rv5j1201	2349	1	The	the	DT
cord-022561-rv5j1201	2349	2	appearance	appearance	NN
cord-022561-rv5j1201	2349	3	of	of	IN
cord-022561-rv5j1201	2349	4	the	the	DT
cord-022561-rv5j1201	2349	5	lymph	lymph	NN
cord-022561-rv5j1201	2349	6	node	node	NN
cord-022561-rv5j1201	2349	7	varies	vary	VBZ
cord-022561-rv5j1201	2349	8	with	with	IN
cord-022561-rv5j1201	2349	9	the	the	DT
cord-022561-rv5j1201	2349	10	immunohistochemistry	immunohistochemistry	NN
cord-022561-rv5j1201	2349	11	(	(	-LRB-
cord-022561-rv5j1201	2349	12	MUM1	MUM1	NNP
cord-022561-rv5j1201	2349	13	/	/	SYM
cord-022561-rv5j1201	2349	14	IRF4	IRF4	NNP
cord-022561-rv5j1201	2349	15	is	be	VBZ
cord-022561-rv5j1201	2349	16	particularly	particularly	RB
cord-022561-rv5j1201	2349	17	sensitive	sensitive	JJ
cord-022561-rv5j1201	2349	18	and	and	CC
cord-022561-rv5j1201	2349	19	specific	specific	JJ
cord-022561-rv5j1201	2349	20	for	for	IN
cord-022561-rv5j1201	2349	21	plasma	plasma	NN
cord-022561-rv5j1201	2349	22	cell	cell	NN
cord-022561-rv5j1201	2349	23	neoplasms	neoplasm	NNS
cord-022561-rv5j1201	2349	24	)	)	-RRB-
cord-022561-rv5j1201	2349	25	.	.	.
cord-022561-rv5j1201	2350	1	Histiocytic	Histiocytic	NNP
cord-022561-rv5j1201	2350	2	Disorders	Disorders	NNPS
cord-022561-rv5j1201	2350	3	.	.	.
cord-022561-rv5j1201	2351	1	Histiocytic	histiocytic	JJ
cord-022561-rv5j1201	2351	2	disorders	disorder	NNS
cord-022561-rv5j1201	2351	3	are	be	VBP
cord-022561-rv5j1201	2351	4	frequently	frequently	RB
cord-022561-rv5j1201	2351	5	diagnosed	diagnose	VBN
cord-022561-rv5j1201	2351	6	in	in	IN
cord-022561-rv5j1201	2351	7	dogs	dog	NNS
cord-022561-rv5j1201	2351	8	and	and	CC
cord-022561-rv5j1201	2351	9	occur	occur	VBP
cord-022561-rv5j1201	2351	10	less	less	RBR
cord-022561-rv5j1201	2351	11	often	often	RB
cord-022561-rv5j1201	2351	12	in	in	IN
cord-022561-rv5j1201	2351	13	cats	cat	NNS
cord-022561-rv5j1201	2351	14	.	.	.
cord-022561-rv5j1201	2352	1	Briefly	briefly	RB
cord-022561-rv5j1201	2352	2	,	,	,
cord-022561-rv5j1201	2352	3	histiocytes	histiocyte	NNS
cord-022561-rv5j1201	2352	4	are	be	VBP
cord-022561-rv5j1201	2352	5	categorized	categorize	VBN
cord-022561-rv5j1201	2352	6	as	as	IN
cord-022561-rv5j1201	2352	7	macrophages	macrophage	NNS
cord-022561-rv5j1201	2352	8	and	and	CC
cord-022561-rv5j1201	2352	9	DCs	dc	NNS
cord-022561-rv5j1201	2352	10	,	,	,
cord-022561-rv5j1201	2352	11	the	the	DT
cord-022561-rv5j1201	2352	12	latter	latter	JJ
cord-022561-rv5j1201	2352	13	of	of	IN
cord-022561-rv5j1201	2352	14	which	which	WDT
cord-022561-rv5j1201	2352	15	are	be	VBP
cord-022561-rv5j1201	2352	16	subdivided	subdivide	VBN
cord-022561-rv5j1201	2352	17	into	into	IN
cord-022561-rv5j1201	2352	18	Langerhans	Langerhans	NNP
cord-022561-rv5j1201	2352	19	cells	cell	NNS
cord-022561-rv5j1201	2352	20	(	(	-LRB-
cord-022561-rv5j1201	2352	21	LCs	LCs	NNP
cord-022561-rv5j1201	2352	22	)	)	-RRB-
cord-022561-rv5j1201	2352	23	,	,	,
cord-022561-rv5j1201	2352	24	found	find	VBN
cord-022561-rv5j1201	2352	25	in	in	IN
cord-022561-rv5j1201	2352	26	skin	skin	NN
cord-022561-rv5j1201	2352	27	,	,	,
cord-022561-rv5j1201	2352	28	gastrointestinal	gastrointestinal	JJ
cord-022561-rv5j1201	2352	29	,	,	,
cord-022561-rv5j1201	2352	30	respiratory	respiratory	JJ
cord-022561-rv5j1201	2352	31	,	,	,
cord-022561-rv5j1201	2352	32	and	and	CC
cord-022561-rv5j1201	2352	33	reproductive	reproductive	JJ
cord-022561-rv5j1201	2352	34	epithelia	epithelium	NNS
cord-022561-rv5j1201	2352	35	(	(	-LRB-
cord-022561-rv5j1201	2352	36	mucosae	mucosae	NNP
cord-022561-rv5j1201	2352	37	)	)	-RRB-
cord-022561-rv5j1201	2352	38	,	,	,
cord-022561-rv5j1201	2352	39	and	and	CC
cord-022561-rv5j1201	2352	40	interstitial	interstitial	JJ
cord-022561-rv5j1201	2352	41	DCs	DCs	NNP
cord-022561-rv5j1201	2352	42	(	(	-LRB-
cord-022561-rv5j1201	2352	43	iDC	iDC	NNP
cord-022561-rv5j1201	2352	44	)	)	-RRB-
cord-022561-rv5j1201	2352	45	,	,	,
cord-022561-rv5j1201	2352	46	located	locate	VBN
cord-022561-rv5j1201	2352	47	in	in	IN
cord-022561-rv5j1201	2352	48	perivascular	perivascular	JJ
cord-022561-rv5j1201	2352	49	spaces	space	NNS
cord-022561-rv5j1201	2352	50	of	of	IN
cord-022561-rv5j1201	2352	51	most	most	JJS
cord-022561-rv5j1201	2352	52	organs	organ	NNS
cord-022561-rv5j1201	2352	53	.	.	.
cord-022561-rv5j1201	2353	1	The	the	DT
cord-022561-rv5j1201	2353	2	term	term	NN
cord-022561-rv5j1201	2353	3	interdigitating	interdigitate	VBG
cord-022561-rv5j1201	2353	4	DCs	DCs	NNP
cord-022561-rv5j1201	2353	5	describes	describe	VBZ
cord-022561-rv5j1201	2353	6	DCs	DCs	NNP
cord-022561-rv5j1201	2353	7	(	(	-LRB-
cord-022561-rv5j1201	2353	8	either	either	DT
cord-022561-rv5j1201	2353	9	resident	resident	NN
cord-022561-rv5j1201	2353	10	or	or	CC
cord-022561-rv5j1201	2353	11	migrating	migrate	VBG
cord-022561-rv5j1201	2353	12	)	)	-RRB-
cord-022561-rv5j1201	2353	13	found	find	VBN
cord-022561-rv5j1201	2353	14	in	in	IN
cord-022561-rv5j1201	2353	15	T	T	NNP
cord-022561-rv5j1201	2353	16	lymphocyte	lymphocyte	NN
cord-022561-rv5j1201	2353	17	regions	region	NNS
cord-022561-rv5j1201	2353	18	of	of	IN
cord-022561-rv5j1201	2353	19	lymph	lymph	NN
cord-022561-rv5j1201	2353	20	nodes	node	NNS
cord-022561-rv5j1201	2353	21	(	(	-LRB-
cord-022561-rv5j1201	2353	22	paracortex	paracortex	NNP
cord-022561-rv5j1201	2353	23	)	)	-RRB-
cord-022561-rv5j1201	2353	24	and	and	CC
cord-022561-rv5j1201	2353	25	spleen	spleen	NNS
cord-022561-rv5j1201	2353	26	(	(	-LRB-
cord-022561-rv5j1201	2353	27	PALS	pals	NN
cord-022561-rv5j1201	2353	28	)	)	-RRB-
cord-022561-rv5j1201	2353	29	;	;	:
cord-022561-rv5j1201	2353	30	interdigitating	interdigitating	NNP
cord-022561-rv5j1201	2353	31	DCs	DCs	NNP
cord-022561-rv5j1201	2353	32	consist	consist	VBP
cord-022561-rv5j1201	2353	33	of	of	IN
cord-022561-rv5j1201	2353	34	both	both	DT
cord-022561-rv5j1201	2353	35	LCs	LCs	NNP
cord-022561-rv5j1201	2353	36	and	and	CC
cord-022561-rv5j1201	2353	37	iDCs	iDCs	NNP
cord-022561-rv5j1201	2353	38	.	.	.
cord-022561-rv5j1201	2354	1	These	these	DT
cord-022561-rv5j1201	2354	2	lineages	lineage	NNS
cord-022561-rv5j1201	2354	3	can	can	MD
cord-022561-rv5j1201	2354	4	be	be	VB
cord-022561-rv5j1201	2354	5	differentiated	differentiate	VBN
cord-022561-rv5j1201	2354	6	using	use	VBG
cord-022561-rv5j1201	2354	7	immunohistochemical	immunohistochemical	JJ
cord-022561-rv5j1201	2354	8	stains	stain	NNS
cord-022561-rv5j1201	2354	9	.	.	.
cord-022561-rv5j1201	2355	1	Histiocytic	histiocytic	JJ
cord-022561-rv5j1201	2355	2	disorders	disorder	NNS
cord-022561-rv5j1201	2355	3	that	that	WDT
cord-022561-rv5j1201	2355	4	are	be	VBP
cord-022561-rv5j1201	2355	5	diagnosed	diagnose	VBN
cord-022561-rv5j1201	2355	6	in	in	IN
cord-022561-rv5j1201	2355	7	veterinary	veterinary	JJ
cord-022561-rv5j1201	2355	8	medicine	medicine	NN
cord-022561-rv5j1201	2355	9	at	at	IN
cord-022561-rv5j1201	2355	10	this	this	DT
cord-022561-rv5j1201	2355	11	time	time	NN
cord-022561-rv5j1201	2355	12	include	include	VBP
cord-022561-rv5j1201	2355	13	the	the	DT
cord-022561-rv5j1201	2355	14	following	follow	VBG
cord-022561-rv5j1201	2355	15	:	:	:
cord-022561-rv5j1201	2355	16	canine	canine	JJ
cord-022561-rv5j1201	2355	17	cutaneous	cutaneous	JJ
cord-022561-rv5j1201	2355	18	histiocytoma	histiocytoma	NN
cord-022561-rv5j1201	2355	19	,	,	,
cord-022561-rv5j1201	2355	20	canine	canine	JJ
cord-022561-rv5j1201	2355	21	LC	LC	NNP
cord-022561-rv5j1201	2355	22	histiocytosis	histiocytosis	NN
cord-022561-rv5j1201	2355	23	,	,	,
cord-022561-rv5j1201	2355	24	canine	canine	JJ
cord-022561-rv5j1201	2355	25	cutaneous	cutaneous	JJ
cord-022561-rv5j1201	2355	26	and	and	CC
cord-022561-rv5j1201	2355	27	systemic	systemic	JJ
cord-022561-rv5j1201	2355	28	histiocytosis	histiocytosis	NN
cord-022561-rv5j1201	2355	29	,	,	,
cord-022561-rv5j1201	2355	30	feline	feline	JJ
cord-022561-rv5j1201	2355	31	pulmonary	pulmonary	JJ
cord-022561-rv5j1201	2355	32	LC	LC	NNP
cord-022561-rv5j1201	2355	33	histiocytosis	histiocytosis	NN
cord-022561-rv5j1201	2355	34	,	,	,
cord-022561-rv5j1201	2355	35	feline	feline	JJ
cord-022561-rv5j1201	2355	36	progressive	progressive	JJ
cord-022561-rv5j1201	2355	37	histiocytosis	histiocytosis	NN
cord-022561-rv5j1201	2355	38	,	,	,
cord-022561-rv5j1201	2355	39	dendritic	dendritic	JJ
cord-022561-rv5j1201	2355	40	cell	cell	NN
cord-022561-rv5j1201	2355	41	leukemia	leukemia	NN
cord-022561-rv5j1201	2355	42	in	in	IN
cord-022561-rv5j1201	2355	43	the	the	DT
cord-022561-rv5j1201	2355	44	dog	dog	NN
cord-022561-rv5j1201	2355	45	,	,	,
cord-022561-rv5j1201	2355	46	and	and	CC
cord-022561-rv5j1201	2355	47	histiocytic	histiocytic	JJ
cord-022561-rv5j1201	2355	48	sarcoma	sarcoma	NN
cord-022561-rv5j1201	2355	49	and	and	CC
cord-022561-rv5j1201	2355	50	hemophagocytic	hemophagocytic	NNP
cord-022561-rv5j1201	2355	51	histiocytic	histiocytic	NNP
cord-022561-rv5j1201	2356	1	sarcoma	sarcoma	NN
cord-022561-rv5j1201	2356	2	in	in	IN
cord-022561-rv5j1201	2356	3	both	both	CC
cord-022561-rv5j1201	2356	4	dogs	dog	NNS
cord-022561-rv5j1201	2356	5	and	and	CC
cord-022561-rv5j1201	2356	6	cats	cat	NNS
cord-022561-rv5j1201	2356	7	.	.	.
cord-022561-rv5j1201	2357	1	Lymph	lymph	NN
cord-022561-rv5j1201	2357	2	node	node	NN
cord-022561-rv5j1201	2357	3	involvement	involvement	NN
cord-022561-rv5j1201	2357	4	is	be	VBZ
cord-022561-rv5j1201	2357	5	seen	see	VBN
cord-022561-rv5j1201	2357	6	in	in	IN
cord-022561-rv5j1201	2357	7	many	many	JJ
cord-022561-rv5j1201	2357	8	of	of	IN
cord-022561-rv5j1201	2357	9	these	these	DT
cord-022561-rv5j1201	2357	10	conditions	condition	NNS
cord-022561-rv5j1201	2357	11	.	.	.
cord-022561-rv5j1201	2358	1	Rare	rare	JJ
cord-022561-rv5j1201	2358	2	reports	report	NNS
cord-022561-rv5j1201	2358	3	of	of	IN
cord-022561-rv5j1201	2358	4	regional	regional	JJ
cord-022561-rv5j1201	2358	5	lymph	lymph	NN
cord-022561-rv5j1201	2358	6	node	node	NN
cord-022561-rv5j1201	2358	7	metastasis	metastasis	NN
cord-022561-rv5j1201	2358	8	in	in	IN
cord-022561-rv5j1201	2358	9	cases	case	NNS
cord-022561-rv5j1201	2358	10	of	of	IN
cord-022561-rv5j1201	2358	11	solitary	solitary	JJ
cord-022561-rv5j1201	2358	12	canine	canine	JJ
cord-022561-rv5j1201	2358	13	cutaneous	cutaneous	JJ
cord-022561-rv5j1201	2358	14	histiocytoma	histiocytoma	NNS
cord-022561-rv5j1201	2358	15	have	have	VBP
cord-022561-rv5j1201	2358	16	been	be	VBN
cord-022561-rv5j1201	2358	17	published	publish	VBN
cord-022561-rv5j1201	2358	18	.	.	.
cord-022561-rv5j1201	2359	1	Lymphatic	lymphatic	JJ
cord-022561-rv5j1201	2359	2	invasion	invasion	NN
cord-022561-rv5j1201	2359	3	with	with	IN
cord-022561-rv5j1201	2359	4	subsequent	subsequent	JJ
cord-022561-rv5j1201	2359	5	regional	regional	JJ
cord-022561-rv5j1201	2359	6	nodal	nodal	JJ
cord-022561-rv5j1201	2359	7	involvement	involvement	NN
cord-022561-rv5j1201	2359	8	may	may	MD
cord-022561-rv5j1201	2359	9	be	be	VB
cord-022561-rv5j1201	2359	10	seen	see	VBN
cord-022561-rv5j1201	2359	11	in	in	IN
cord-022561-rv5j1201	2359	12	dogs	dog	NNS
cord-022561-rv5j1201	2359	13	with	with	IN
cord-022561-rv5j1201	2359	14	LC	LC	NNP
cord-022561-rv5j1201	2359	15	histiocytosis	histiocytosis	NN
cord-022561-rv5j1201	2359	16	,	,	,
cord-022561-rv5j1201	2359	17	which	which	WDT
cord-022561-rv5j1201	2359	18	is	be	VBZ
cord-022561-rv5j1201	2359	19	a	a	DT
cord-022561-rv5j1201	2359	20	poor	poor	JJ
cord-022561-rv5j1201	2359	21	prognostic	prognostic	JJ
cord-022561-rv5j1201	2359	22	indicator	indicator	NN
cord-022561-rv5j1201	2359	23	and	and	CC
cord-022561-rv5j1201	2359	24	likely	likely	RB
cord-022561-rv5j1201	2359	25	reflects	reflect	VBZ
cord-022561-rv5j1201	2359	26	systemic	systemic	JJ
cord-022561-rv5j1201	2359	27	infiltration	infiltration	NN
cord-022561-rv5j1201	2359	28	.	.	.
cord-022561-rv5j1201	2360	1	The	the	DT
cord-022561-rv5j1201	2360	2	normal	normal	JJ
cord-022561-rv5j1201	2360	3	architecture	architecture	NN
cord-022561-rv5j1201	2360	4	of	of	IN
cord-022561-rv5j1201	2360	5	tracheobronchial	tracheobronchial	JJ
cord-022561-rv5j1201	2360	6	lymph	lymph	NN
cord-022561-rv5j1201	2360	7	nodes	node	NNS
cord-022561-rv5j1201	2360	8	is	be	VBZ
cord-022561-rv5j1201	2360	9	often	often	RB
cord-022561-rv5j1201	2360	10	effaced	efface	VBN
cord-022561-rv5j1201	2360	11	in	in	IN
cord-022561-rv5j1201	2360	12	cats	cat	NNS
cord-022561-rv5j1201	2360	13	with	with	IN
cord-022561-rv5j1201	2360	14	pulmonary	pulmonary	JJ
cord-022561-rv5j1201	2360	15	LC	LC	NNP
cord-022561-rv5j1201	2360	16	histiocytosis	histiocytosis	NN
cord-022561-rv5j1201	2360	17	.	.	.
cord-022561-rv5j1201	2361	1	Canine	canine	JJ
cord-022561-rv5j1201	2361	2	reactive	reactive	JJ
cord-022561-rv5j1201	2361	3	histiocytoses	histiocytose	NNS
cord-022561-rv5j1201	2361	4	are	be	VBP
cord-022561-rv5j1201	2361	5	not	not	RB
cord-022561-rv5j1201	2361	6	clonal	clonal	JJ
cord-022561-rv5j1201	2361	7	neoplastic	neoplastic	JJ
cord-022561-rv5j1201	2361	8	proliferations	proliferation	NNS
cord-022561-rv5j1201	2361	9	but	but	CC
cord-022561-rv5j1201	2361	10	likely	likely	RB
cord-022561-rv5j1201	2361	11	reflect	reflect	VB
cord-022561-rv5j1201	2361	12	an	an	DT
cord-022561-rv5j1201	2361	13	immune	immune	JJ
cord-022561-rv5j1201	2361	14	dysregulation	dysregulation	NN
cord-022561-rv5j1201	2361	15	consisting	consist	VBG
cord-022561-rv5j1201	2361	16	of	of	IN
cord-022561-rv5j1201	2361	17	activated	activate	VBN
cord-022561-rv5j1201	2361	18	dermal	dermal	JJ
cord-022561-rv5j1201	2361	19	iDCs	idcs	XX
cord-022561-rv5j1201	2361	20	(	(	-LRB-
cord-022561-rv5j1201	2361	21	and	and	CC
cord-022561-rv5j1201	2361	22	T	T	NNP
cord-022561-rv5j1201	2361	23	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	2361	24	)	)	-RRB-
cord-022561-rv5j1201	2361	25	.	.	.
cord-022561-rv5j1201	2362	1	They	-PRON-	PRP
cord-022561-rv5j1201	2362	2	are	be	VBP
cord-022561-rv5j1201	2362	3	categorized	categorize	VBN
cord-022561-rv5j1201	2362	4	as	as	IN
cord-022561-rv5j1201	2362	5	cutaneous	cutaneous	JJ
cord-022561-rv5j1201	2362	6	histiocytosis	histiocytosis	NN
cord-022561-rv5j1201	2362	7	(	(	-LRB-
cord-022561-rv5j1201	2362	8	CH	CH	NNP
cord-022561-rv5j1201	2362	9	)	)	-RRB-
cord-022561-rv5j1201	2362	10	,	,	,
cord-022561-rv5j1201	2362	11	involving	involve	VBG
cord-022561-rv5j1201	2362	12	skin	skin	NN
cord-022561-rv5j1201	2362	13	and	and	CC
cord-022561-rv5j1201	2362	14	draining	drain	VBG
cord-022561-rv5j1201	2362	15	lymph	lymph	NN
cord-022561-rv5j1201	2362	16	nodes	node	NNS
cord-022561-rv5j1201	2362	17	,	,	,
cord-022561-rv5j1201	2362	18	and	and	CC
cord-022561-rv5j1201	2362	19	a	a	DT
cord-022561-rv5j1201	2362	20	more	more	RBR
cord-022561-rv5j1201	2362	21	generalized	generalized	JJ
cord-022561-rv5j1201	2362	22	systemic	systemic	JJ
cord-022561-rv5j1201	2362	23	histiocytosis	histiocytosis	NN
cord-022561-rv5j1201	2362	24	(	(	-LRB-
cord-022561-rv5j1201	2362	25	SH	SH	NNP
cord-022561-rv5j1201	2362	26	)	)	-RRB-
cord-022561-rv5j1201	2362	27	,	,	,
cord-022561-rv5j1201	2362	28	affecting	affect	VBG
cord-022561-rv5j1201	2362	29	skin	skin	NN
cord-022561-rv5j1201	2362	30	and	and	CC
cord-022561-rv5j1201	2362	31	other	other	JJ
cord-022561-rv5j1201	2362	32	sites	site	NNS
cord-022561-rv5j1201	2362	33	(	(	-LRB-
cord-022561-rv5j1201	2362	34	e.g.	e.g.	RB
cord-022561-rv5j1201	2362	35	,	,	,
cord-022561-rv5j1201	2362	36	lung	lung	NN
cord-022561-rv5j1201	2362	37	,	,	,
cord-022561-rv5j1201	2362	38	liver	liver	NN
cord-022561-rv5j1201	2362	39	,	,	,
cord-022561-rv5j1201	2362	40	bone	bone	NN
cord-022561-rv5j1201	2362	41	marrow	marrow	NN
cord-022561-rv5j1201	2362	42	,	,	,
cord-022561-rv5j1201	2362	43	spleen	spleen	NNS
cord-022561-rv5j1201	2362	44	,	,	,
cord-022561-rv5j1201	2362	45	lymph	lymph	NN
cord-022561-rv5j1201	2362	46	nodes	node	NNS
cord-022561-rv5j1201	2362	47	,	,	,
cord-022561-rv5j1201	2362	48	kidneys	kidney	NNS
cord-022561-rv5j1201	2362	49	,	,	,
cord-022561-rv5j1201	2362	50	and	and	CC
cord-022561-rv5j1201	2362	51	orbital	orbital	JJ
cord-022561-rv5j1201	2362	52	and	and	CC
cord-022561-rv5j1201	2362	53	nasal	nasal	JJ
cord-022561-rv5j1201	2362	54	tissues	tissue	NNS
cord-022561-rv5j1201	2362	55	)	)	-RRB-
cord-022561-rv5j1201	2362	56	.	.	.
cord-022561-rv5j1201	2363	1	Histiocytic	Histiocytic	NNP
cord-022561-rv5j1201	2363	2	Sarcoma	Sarcoma	NNP
cord-022561-rv5j1201	2363	3	Complex	Complex	NNP
cord-022561-rv5j1201	2363	4	.	.	.
cord-022561-rv5j1201	2364	1	Histiocytic	histiocytic	JJ
cord-022561-rv5j1201	2364	2	sarcomas	sarcoma	NNS
cord-022561-rv5j1201	2364	3	(	(	-LRB-
cord-022561-rv5j1201	2364	4	HSs	HSs	NNP
cord-022561-rv5j1201	2364	5	)	)	-RRB-
cord-022561-rv5j1201	2364	6	are	be	VBP
cord-022561-rv5j1201	2364	7	neoplasms	neoplasm	NNS
cord-022561-rv5j1201	2364	8	of	of	IN
cord-022561-rv5j1201	2364	9	iDCs	idc	NNS
cord-022561-rv5j1201	2364	10	and	and	CC
cord-022561-rv5j1201	2364	11	therefore	therefore	RB
cord-022561-rv5j1201	2364	12	can	can	MD
cord-022561-rv5j1201	2364	13	arise	arise	VB
cord-022561-rv5j1201	2364	14	in	in	IN
cord-022561-rv5j1201	2364	15	almost	almost	RB
cord-022561-rv5j1201	2364	16	any	any	DT
cord-022561-rv5j1201	2364	17	tissue	tissue	NN
cord-022561-rv5j1201	2364	18	,	,	,
cord-022561-rv5j1201	2364	19	frequently	frequently	RB
cord-022561-rv5j1201	2364	20	the	the	DT
cord-022561-rv5j1201	2364	21	spleen	spleen	NN
cord-022561-rv5j1201	2364	22	,	,	,
cord-022561-rv5j1201	2364	23	lung	lung	NN
cord-022561-rv5j1201	2364	24	,	,	,
cord-022561-rv5j1201	2364	25	skin	skin	NN
cord-022561-rv5j1201	2364	26	,	,	,
cord-022561-rv5j1201	2364	27	meninges	meninge	NNS
cord-022561-rv5j1201	2364	28	,	,	,
cord-022561-rv5j1201	2364	29	lymph	lymph	NN
cord-022561-rv5j1201	2364	30	nodes	node	NNS
cord-022561-rv5j1201	2364	31	,	,	,
cord-022561-rv5j1201	2364	32	bone	bone	NN
cord-022561-rv5j1201	2364	33	marrow	marrow	NN
cord-022561-rv5j1201	2364	34	,	,	,
cord-022561-rv5j1201	2364	35	and	and	CC
cord-022561-rv5j1201	2364	36	synovium	synovium	NN
cord-022561-rv5j1201	2364	37	.	.	.
cord-022561-rv5j1201	2365	1	Secondary	secondary	JJ
cord-022561-rv5j1201	2365	2	involvement	involvement	NN
cord-022561-rv5j1201	2365	3	of	of	IN
cord-022561-rv5j1201	2365	4	the	the	DT
cord-022561-rv5j1201	2365	5	liver	liver	NN
cord-022561-rv5j1201	2365	6	is	be	VBZ
cord-022561-rv5j1201	2365	7	common	common	JJ
cord-022561-rv5j1201	2365	8	as	as	IN
cord-022561-rv5j1201	2365	9	the	the	DT
cord-022561-rv5j1201	2365	10	disease	disease	NN
cord-022561-rv5j1201	2365	11	progresses	progress	VBZ
cord-022561-rv5j1201	2365	12	.	.	.
cord-022561-rv5j1201	2366	1	This	this	DT
cord-022561-rv5j1201	2366	2	neoplasm	neoplasm	NN
cord-022561-rv5j1201	2366	3	is	be	VBZ
cord-022561-rv5j1201	2366	4	most	most	RBS
cord-022561-rv5j1201	2366	5	commonly	commonly	RB
cord-022561-rv5j1201	2366	6	diagnosed	diagnose	VBN
cord-022561-rv5j1201	2366	7	in	in	IN
cord-022561-rv5j1201	2366	8	dogs	dog	NNS
cord-022561-rv5j1201	2366	9	,	,	,
cord-022561-rv5j1201	2366	10	and	and	CC
cord-022561-rv5j1201	2366	11	a	a	DT
cord-022561-rv5j1201	2366	12	lower	low	JJR
cord-022561-rv5j1201	2366	13	incidence	incidence	NN
cord-022561-rv5j1201	2366	14	is	be	VBZ
cord-022561-rv5j1201	2366	15	seen	see	VBN
cord-022561-rv5j1201	2366	16	in	in	IN
cord-022561-rv5j1201	2366	17	cats	cat	NNS
cord-022561-rv5j1201	2366	18	.	.	.
cord-022561-rv5j1201	2367	1	Localized	localized	JJ
cord-022561-rv5j1201	2367	2	histiocytic	histiocytic	JJ
cord-022561-rv5j1201	2367	3	sarcoma	sarcoma	NN
cord-022561-rv5j1201	2367	4	may	may	MD
cord-022561-rv5j1201	2367	5	be	be	VB
cord-022561-rv5j1201	2367	6	a	a	DT
cord-022561-rv5j1201	2367	7	focal	focal	JJ
cord-022561-rv5j1201	2367	8	solitary	solitary	JJ
cord-022561-rv5j1201	2367	9	lesion	lesion	NN
cord-022561-rv5j1201	2367	10	or	or	CC
cord-022561-rv5j1201	2367	11	multiple	multiple	JJ
cord-022561-rv5j1201	2367	12	nodules	nodule	NNS
cord-022561-rv5j1201	2367	13	within	within	IN
cord-022561-rv5j1201	2367	14	a	a	DT
cord-022561-rv5j1201	2367	15	single	single	JJ
cord-022561-rv5j1201	2367	16	organ	organ	NN
cord-022561-rv5j1201	2367	17	.	.	.
cord-022561-rv5j1201	2368	1	Disseminated	disseminate	VBN
cord-022561-rv5j1201	2368	2	histiocytic	histiocytic	NNP
cord-022561-rv5j1201	2369	1	sarcoma	sarcoma	NN
cord-022561-rv5j1201	2369	2	describes	describe	VBZ
cord-022561-rv5j1201	2369	3	classify	classify	VBP
cord-022561-rv5j1201	2369	4	lymphomas	lymphoma	NNS
cord-022561-rv5j1201	2369	5	.	.	.
cord-022561-rv5j1201	2370	1	The	the	DT
cord-022561-rv5j1201	2370	2	morphologic	morphologic	JJ
cord-022561-rv5j1201	2370	3	features	feature	NNS
cord-022561-rv5j1201	2370	4	used	use	VBN
cord-022561-rv5j1201	2370	5	in	in	IN
cord-022561-rv5j1201	2370	6	histopathologic	histopathologic	JJ
cord-022561-rv5j1201	2370	7	classification	classification	NN
cord-022561-rv5j1201	2370	8	are	be	VBP
cord-022561-rv5j1201	2370	9	the	the	DT
cord-022561-rv5j1201	2370	10	following	follow	VBG
cord-022561-rv5j1201	2370	11	:	:	:
cord-022561-rv5j1201	2370	12	•	•	XX
cord-022561-rv5j1201	2371	1	Histologic	Histologic	NNP
cord-022561-rv5j1201	2371	2	pattern	pattern	NN
cord-022561-rv5j1201	2371	3	-	-	:
cord-022561-rv5j1201	2371	4	Nodular	Nodular	NNP
cord-022561-rv5j1201	2371	5	or	or	CC
cord-022561-rv5j1201	2371	6	diffuse	diffuse	VB
cord-022561-rv5j1201	2371	7	.	.	.
cord-022561-rv5j1201	2372	1	•	•	NNP
cord-022561-rv5j1201	2373	1	Cell	cell	NN
cord-022561-rv5j1201	2373	2	size-	size-	XX
cord-022561-rv5j1201	2374	1	The	the	DT
cord-022561-rv5j1201	2374	2	nuclei	nucleus	NNS
cord-022561-rv5j1201	2374	3	of	of	IN
cord-022561-rv5j1201	2374	4	the	the	DT
cord-022561-rv5j1201	2374	5	neoplastic	neoplastic	JJ
cord-022561-rv5j1201	2374	6	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	2374	7	are	be	VBP
cord-022561-rv5j1201	2374	8	compared	compare	VBN
cord-022561-rv5j1201	2374	9	to	to	IN
cord-022561-rv5j1201	2374	10	the	the	DT
cord-022561-rv5j1201	2374	11	diameter	diameter	NN
cord-022561-rv5j1201	2374	12	of	of	IN
cord-022561-rv5j1201	2374	13	a	a	DT
cord-022561-rv5j1201	2374	14	red	red	JJ
cord-022561-rv5j1201	2374	15	blood	blood	NN
cord-022561-rv5j1201	2374	16	cell	cell	NN
cord-022561-rv5j1201	2374	17	(	(	-LRB-
cord-022561-rv5j1201	2374	18	RBC	RBC	NNP
cord-022561-rv5j1201	2374	19	≅	≅	NNP
cord-022561-rv5j1201	2374	20	5	5	CD
cord-022561-rv5j1201	2374	21	µm	µm	CD
cord-022561-rv5j1201	2374	22	)	)	-RRB-
cord-022561-rv5j1201	2374	23	.	.	.
cord-022561-rv5j1201	2375	1	Small	small	JJ
cord-022561-rv5j1201	2375	2	is	be	VBZ
cord-022561-rv5j1201	2375	3	less	less	JJR
cord-022561-rv5j1201	2375	4	than	than	IN
cord-022561-rv5j1201	2375	5	1.5	1.5	CD
cord-022561-rv5j1201	2375	6	times	time	NNS
cord-022561-rv5j1201	2375	7	the	the	DT
cord-022561-rv5j1201	2375	8	diameter	diameter	NN
cord-022561-rv5j1201	2375	9	of	of	IN
cord-022561-rv5j1201	2375	10	an	an	DT
cord-022561-rv5j1201	2375	11	RBC	RBC	NNP
cord-022561-rv5j1201	2375	12	;	;	:
cord-022561-rv5j1201	2375	13	intermediate	intermediate	JJ
cord-022561-rv5j1201	2375	14	is	be	VBZ
cord-022561-rv5j1201	2375	15	1.5	1.5	CD
cord-022561-rv5j1201	2375	16	to	to	TO
cord-022561-rv5j1201	2375	17	2.0	2.0	CD
cord-022561-rv5j1201	2375	18	times	time	NNS
cord-022561-rv5j1201	2375	19	the	the	DT
cord-022561-rv5j1201	2375	20	diameter	diameter	NN
cord-022561-rv5j1201	2375	21	of	of	IN
cord-022561-rv5j1201	2375	22	an	an	DT
cord-022561-rv5j1201	2375	23	RBC	RBC	NNP
cord-022561-rv5j1201	2375	24	;	;	:
cord-022561-rv5j1201	2375	25	large	large	JJ
cord-022561-rv5j1201	2375	26	is	be	VBZ
cord-022561-rv5j1201	2375	27	more	more	JJR
cord-022561-rv5j1201	2375	28	than	than	IN
cord-022561-rv5j1201	2375	29	2.0	2.0	CD
cord-022561-rv5j1201	2375	30	times	time	NNS
cord-022561-rv5j1201	2375	31	the	the	DT
cord-022561-rv5j1201	2375	32	diameter	diameter	NN
cord-022561-rv5j1201	2375	33	of	of	IN
cord-022561-rv5j1201	2375	34	an	an	DT
cord-022561-rv5j1201	2375	35	RBC	RBC	NNP
cord-022561-rv5j1201	2375	36	.	.	.
cord-022561-rv5j1201	2376	1	•	•	NNP
cord-022561-rv5j1201	2377	1	Grade	grade	NN
cord-022561-rv5j1201	2377	2	-	-	HYPH
cord-022561-rv5j1201	2377	3	Mitotic	mitotic	JJ
cord-022561-rv5j1201	2377	4	figures	figure	NNS
cord-022561-rv5j1201	2377	5	are	be	VBP
cord-022561-rv5j1201	2377	6	counted	count	VBN
cord-022561-rv5j1201	2377	7	in	in	IN
cord-022561-rv5j1201	2377	8	a	a	DT
cord-022561-rv5j1201	2377	9	single	single	JJ
cord-022561-rv5j1201	2377	10	high	high	JJ
cord-022561-rv5j1201	2377	11	-	-	HYPH
cord-022561-rv5j1201	2377	12	power	power	NN
cord-022561-rv5j1201	2377	13	(	(	-LRB-
cord-022561-rv5j1201	2377	14	400×	400×	CD
cord-022561-rv5j1201	2377	15	)	)	-RRB-
cord-022561-rv5j1201	2377	16	field	field	NN
cord-022561-rv5j1201	2377	17	.	.	.
cord-022561-rv5j1201	2378	1	Indolent	indolent	JJ
cord-022561-rv5j1201	2378	2	is	be	VBZ
cord-022561-rv5j1201	2378	3	0	0	CD
cord-022561-rv5j1201	2378	4	to	to	IN
cord-022561-rv5j1201	2378	5	1	1	CD
cord-022561-rv5j1201	2378	6	;	;	:
cord-022561-rv5j1201	2378	7	low	low	JJ
cord-022561-rv5j1201	2378	8	is	be	VBZ
cord-022561-rv5j1201	2378	9	2	2	CD
cord-022561-rv5j1201	2378	10	to	to	IN
cord-022561-rv5j1201	2378	11	5	5	CD
cord-022561-rv5j1201	2378	12	;	;	:
cord-022561-rv5j1201	2378	13	mid	mid	NNP
cord-022561-rv5j1201	2378	14	is	be	VBZ
cord-022561-rv5j1201	2378	15	6	6	CD
cord-022561-rv5j1201	2378	16	to	to	TO
cord-022561-rv5j1201	2378	17	10	10	CD
cord-022561-rv5j1201	2378	18	;	;	:
cord-022561-rv5j1201	2378	19	high	high	JJ
cord-022561-rv5j1201	2378	20	is	be	VBZ
cord-022561-rv5j1201	2378	21	more	more	JJR
cord-022561-rv5j1201	2378	22	than	than	IN
cord-022561-rv5j1201	2378	23	10	10	CD
cord-022561-rv5j1201	2378	24	.	.	.
cord-022561-rv5j1201	2379	1	Although	although	IN
cord-022561-rv5j1201	2379	2	there	there	EX
cord-022561-rv5j1201	2379	3	are	be	VBP
cord-022561-rv5j1201	2379	4	numerous	numerous	JJ
cord-022561-rv5j1201	2379	5	subtypes	subtype	NNS
cord-022561-rv5j1201	2379	6	of	of	IN
cord-022561-rv5j1201	2379	7	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2379	8	recognized	recognize	VBN
cord-022561-rv5j1201	2379	9	under	under	IN
cord-022561-rv5j1201	2379	10	the	the	DT
cord-022561-rv5j1201	2379	11	WHO	WHO	NNP
cord-022561-rv5j1201	2379	12	system	system	NN
cord-022561-rv5j1201	2379	13	,	,	,
cord-022561-rv5j1201	2379	14	a	a	DT
cord-022561-rv5j1201	2379	15	detailed	detailed	JJ
cord-022561-rv5j1201	2379	16	discussion	discussion	NN
cord-022561-rv5j1201	2379	17	of	of	IN
cord-022561-rv5j1201	2379	18	each	each	DT
cord-022561-rv5j1201	2379	19	subtype	subtype	NN
cord-022561-rv5j1201	2379	20	is	be	VBZ
cord-022561-rv5j1201	2379	21	outside	outside	IN
cord-022561-rv5j1201	2379	22	the	the	DT
cord-022561-rv5j1201	2379	23	scope	scope	NN
cord-022561-rv5j1201	2379	24	of	of	IN
cord-022561-rv5j1201	2379	25	this	this	DT
cord-022561-rv5j1201	2379	26	textbook	textbook	NN
cord-022561-rv5j1201	2379	27	.	.	.
cord-022561-rv5j1201	2380	1	However	however	RB
cord-022561-rv5j1201	2380	2	,	,	,
cord-022561-rv5j1201	2380	3	a	a	DT
cord-022561-rv5j1201	2380	4	select	select	JJ
cord-022561-rv5j1201	2380	5	number	number	NN
cord-022561-rv5j1201	2380	6	of	of	IN
cord-022561-rv5j1201	2380	7	subtypes	subtype	NNS
cord-022561-rv5j1201	2380	8	are	be	VBP
cord-022561-rv5j1201	2380	9	more	more	RBR
cord-022561-rv5j1201	2380	10	commonly	commonly	RB
cord-022561-rv5j1201	2380	11	seen	see	VBN
cord-022561-rv5j1201	2380	12	in	in	IN
cord-022561-rv5j1201	2380	13	domestic	domestic	JJ
cord-022561-rv5j1201	2380	14	animals	animal	NNS
cord-022561-rv5j1201	2380	15	(	(	-LRB-
cord-022561-rv5j1201	2380	16	see	see	VB
cord-022561-rv5j1201	2380	17	Table	Table	NNP
cord-022561-rv5j1201	2380	18	 	 	_SP
cord-022561-rv5j1201	2380	19	13	13	CD
cord-022561-rv5j1201	2380	20	-7	-7	CD
cord-022561-rv5j1201	2380	21	)	)	-RRB-
cord-022561-rv5j1201	2380	22	and	and	CC
cord-022561-rv5j1201	2380	23	currently	currently	RB
cord-022561-rv5j1201	2380	24	best	best	RB
cord-022561-rv5j1201	2380	25	described	describe	VBN
cord-022561-rv5j1201	2380	26	in	in	IN
cord-022561-rv5j1201	2380	27	the	the	DT
cord-022561-rv5j1201	2380	28	dog	dog	NN
cord-022561-rv5j1201	2380	29	(	(	-LRB-
cord-022561-rv5j1201	2380	30	see	see	VB
cord-022561-rv5j1201	2380	31	Disorders	disorder	NNS
cord-022561-rv5j1201	2380	32	of	of	IN
cord-022561-rv5j1201	2380	33	Dogs	Dogs	NNP
cord-022561-rv5j1201	2380	34	,	,	,
cord-022561-rv5j1201	2380	35	Neoplasms	Neoplasms	NNP
cord-022561-rv5j1201	2380	36	,	,	,
cord-022561-rv5j1201	2380	37	Lymphomas	Lymphomas	NNP
cord-022561-rv5j1201	2380	38	)	)	-RRB-
cord-022561-rv5j1201	2380	39	.	.	.
cord-022561-rv5j1201	2381	1	The	the	DT
cord-022561-rv5j1201	2381	2	most	most	RBS
cord-022561-rv5j1201	2381	3	common	common	JJ
cord-022561-rv5j1201	2381	4	types	type	NNS
cord-022561-rv5j1201	2381	5	in	in	IN
cord-022561-rv5j1201	2381	6	dogs	dog	NNS
cord-022561-rv5j1201	2381	7	are	be	VBP
cord-022561-rv5j1201	2381	8	large	large	JJ
cord-022561-rv5j1201	2381	9	cell	cell	NN
cord-022561-rv5j1201	2381	10	lymphomas	lymphoma	NNS
cord-022561-rv5j1201	2381	11	and	and	CC
cord-022561-rv5j1201	2381	12	include	include	VBP
cord-022561-rv5j1201	2381	13	diffuse	diffuse	VB
cord-022561-rv5j1201	2381	14	large	large	JJ
cord-022561-rv5j1201	2381	15	B	b	NN
cord-022561-rv5j1201	2381	16	cell	cell	NN
cord-022561-rv5j1201	2381	17	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2381	18	and	and	CC
cord-022561-rv5j1201	2381	19	peripheral	peripheral	JJ
cord-022561-rv5j1201	2381	20	T	T	NNP
cord-022561-rv5j1201	2381	21	cell	cell	NN
cord-022561-rv5j1201	2381	22	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2381	23	.	.	.
cord-022561-rv5j1201	2382	1	T	T	NNP
cord-022561-rv5j1201	2382	2	cell	cell	NN
cord-022561-rv5j1201	2382	3	-	-	HYPH
cord-022561-rv5j1201	2382	4	rich	rich	JJ
cord-022561-rv5j1201	2382	5	large	large	JJ
cord-022561-rv5j1201	2382	6	B	b	NN
cord-022561-rv5j1201	2382	7	cell	cell	NN
cord-022561-rv5j1201	2382	8	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2382	9	is	be	VBZ
cord-022561-rv5j1201	2382	10	thought	think	VBN
cord-022561-rv5j1201	2382	11	to	to	TO
cord-022561-rv5j1201	2382	12	be	be	VB
cord-022561-rv5j1201	2382	13	a	a	DT
cord-022561-rv5j1201	2382	14	variant	variant	NN
cord-022561-rv5j1201	2382	15	of	of	IN
cord-022561-rv5j1201	2382	16	diffuse	diffuse	JJ
cord-022561-rv5j1201	2382	17	large	large	JJ
cord-022561-rv5j1201	2382	18	B	b	NN
cord-022561-rv5j1201	2382	19	cell	cell	NN
cord-022561-rv5j1201	2382	20	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2382	21	with	with	IN
cord-022561-rv5j1201	2382	22	a	a	DT
cord-022561-rv5j1201	2382	23	distinctive	distinctive	JJ
cord-022561-rv5j1201	2382	24	reactive	reactive	JJ
cord-022561-rv5j1201	2382	25	T	t	NN
cord-022561-rv5j1201	2382	26	lymphocyte	lymphocyte	NN
cord-022561-rv5j1201	2382	27	infiltrate	infiltrate	NN
cord-022561-rv5j1201	2382	28	.	.	.
cord-022561-rv5j1201	2383	1	Intermediate	intermediate	JJ
cord-022561-rv5j1201	2383	2	cell	cell	NN
cord-022561-rv5j1201	2383	3	lymphomas	lymphoma	NNS
cord-022561-rv5j1201	2383	4	include	include	VBP
cord-022561-rv5j1201	2383	5	B	b	NN
cord-022561-rv5j1201	2383	6	or	or	CC
cord-022561-rv5j1201	2383	7	T	t	NN
cord-022561-rv5j1201	2383	8	lymphocyte	lymphocyte	NN
cord-022561-rv5j1201	2383	9	lymphoblastic	lymphoblastic	NN
cord-022561-rv5j1201	2383	10	lymphomas	lymphoma	NNS
cord-022561-rv5j1201	2383	11	and	and	CC
cord-022561-rv5j1201	2383	12	Burkitt	Burkitt	NNP
cord-022561-rv5j1201	2383	13	-	-	HYPH
cord-022561-rv5j1201	2383	14	like	like	JJ
cord-022561-rv5j1201	2383	15	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2383	16	(	(	-LRB-
cord-022561-rv5j1201	2383	17	both	both	DT
cord-022561-rv5j1201	2383	18	high	high	JJ
cord-022561-rv5j1201	2383	19	grade	grade	NN
cord-022561-rv5j1201	2383	20	)	)	-RRB-
cord-022561-rv5j1201	2383	21	,	,	,
cord-022561-rv5j1201	2383	22	marginal	marginal	JJ
cord-022561-rv5j1201	2383	23	zone	zone	NN
cord-022561-rv5j1201	2383	24	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2383	25	,	,	,
cord-022561-rv5j1201	2383	26	and	and	CC
cord-022561-rv5j1201	2383	27	the	the	DT
cord-022561-rv5j1201	2383	28	intermediate	intermediate	JJ
cord-022561-rv5j1201	2383	29	cell	cell	NN
cord-022561-rv5j1201	2383	30	variant	variant	NN
cord-022561-rv5j1201	2383	31	of	of	IN
cord-022561-rv5j1201	2383	32	T	T	NNP
cord-022561-rv5j1201	2383	33	zone	zone	NN
cord-022561-rv5j1201	2383	34	lymphomas	lymphoma	NNS
cord-022561-rv5j1201	2383	35	(	(	-LRB-
cord-022561-rv5j1201	2383	36	both	both	DT
cord-022561-rv5j1201	2383	37	indolent	indolent	JJ
cord-022561-rv5j1201	2383	38	and	and	CC
cord-022561-rv5j1201	2383	39	nodular	nodular	JJ
cord-022561-rv5j1201	2383	40	)	)	-RRB-
cord-022561-rv5j1201	2383	41	.	.	.
cord-022561-rv5j1201	2384	1	Small	small	JJ
cord-022561-rv5j1201	2384	2	cell	cell	NN
cord-022561-rv5j1201	2384	3	lymphomas	lymphoma	NNS
cord-022561-rv5j1201	2384	4	most	most	RBS
cord-022561-rv5j1201	2384	5	commonly	commonly	RB
cord-022561-rv5j1201	2384	6	diagnosed	diagnose	VBN
cord-022561-rv5j1201	2384	7	in	in	IN
cord-022561-rv5j1201	2384	8	domestic	domestic	JJ
cord-022561-rv5j1201	2384	9	animal	animal	NN
cord-022561-rv5j1201	2384	10	species	specie	NNS
cord-022561-rv5j1201	2384	11	include	include	VBP
cord-022561-rv5j1201	2384	12	enteropathy	enteropathy	NNP
cord-022561-rv5j1201	2384	13	-	-	HYPH
cord-022561-rv5j1201	2384	14	associated	associate	VBN
cord-022561-rv5j1201	2384	15	T	T	NNP
cord-022561-rv5j1201	2384	16	cell	cell	NN
cord-022561-rv5j1201	2384	17	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2384	18	,	,	,
cord-022561-rv5j1201	2384	19	commonly	commonly	RB
cord-022561-rv5j1201	2384	20	seen	see	VBN
cord-022561-rv5j1201	2384	21	in	in	IN
cord-022561-rv5j1201	2384	22	the	the	DT
cord-022561-rv5j1201	2384	23	cat	cat	NN
cord-022561-rv5j1201	2384	24	,	,	,
cord-022561-rv5j1201	2384	25	T	t	NN
cord-022561-rv5j1201	2384	26	zone	zone	NN
cord-022561-rv5j1201	2384	27	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2384	28	(	(	-LRB-
cord-022561-rv5j1201	2384	29	small	small	JJ
cord-022561-rv5j1201	2384	30	cell	cell	NN
cord-022561-rv5j1201	2384	31	variant	variant	NN
cord-022561-rv5j1201	2384	32	)	)	-RRB-
cord-022561-rv5j1201	2384	33	,	,	,
cord-022561-rv5j1201	2384	34	and	and	CC
cord-022561-rv5j1201	2384	35	small	small	JJ
cord-022561-rv5j1201	2384	36	cell	cell	NN
cord-022561-rv5j1201	2384	37	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2384	38	.	.	.
cord-022561-rv5j1201	2385	1	Cutaneous	cutaneous	JJ
cord-022561-rv5j1201	2385	2	lymphomas	lymphoma	NNS
cord-022561-rv5j1201	2385	3	are	be	VBP
cord-022561-rv5j1201	2385	4	most	most	RBS
cord-022561-rv5j1201	2385	5	often	often	RB
cord-022561-rv5j1201	2385	6	of	of	IN
cord-022561-rv5j1201	2385	7	T	T	NNP
cord-022561-rv5j1201	2385	8	lymphocyte	lymphocyte	NN
cord-022561-rv5j1201	2385	9	origin	origin	NN
cord-022561-rv5j1201	2385	10	and	and	CC
cord-022561-rv5j1201	2385	11	may	may	MD
cord-022561-rv5j1201	2385	12	be	be	VB
cord-022561-rv5j1201	2385	13	epitheliotropic	epitheliotropic	NNP
cord-022561-rv5j1201	2385	14	or	or	CC
cord-022561-rv5j1201	2385	15	nonepitheliotropic	nonepitheliotropic	NNP
cord-022561-rv5j1201	2385	16	,	,	,
cord-022561-rv5j1201	2385	17	and	and	CC
cord-022561-rv5j1201	2385	18	a	a	DT
cord-022561-rv5j1201	2385	19	distinct	distinct	JJ
cord-022561-rv5j1201	2385	20	entity	entity	NN
cord-022561-rv5j1201	2385	21	of	of	IN
cord-022561-rv5j1201	2385	22	inflamed	inflamed	JJ
cord-022561-rv5j1201	2385	23	T	t	NN
cord-022561-rv5j1201	2385	24	cell	cell	NN
cord-022561-rv5j1201	2385	25	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2385	26	has	have	VBZ
cord-022561-rv5j1201	2385	27	been	be	VBN
cord-022561-rv5j1201	2385	28	recently	recently	RB
cord-022561-rv5j1201	2385	29	described	describe	VBN
cord-022561-rv5j1201	2385	30	in	in	IN
cord-022561-rv5j1201	2385	31	dogs	dog	NNS
cord-022561-rv5j1201	2385	32	(	(	-LRB-
cord-022561-rv5j1201	2385	33	see	see	VB
cord-022561-rv5j1201	2385	34	Chapter	Chapter	NNP
cord-022561-rv5j1201	2385	35	17	17	CD
cord-022561-rv5j1201	2385	36	)	)	-RRB-
cord-022561-rv5j1201	2385	37	.	.	.
cord-022561-rv5j1201	2386	1	Plasma	plasma	NN
cord-022561-rv5j1201	2386	2	Cell	cell	NN
cord-022561-rv5j1201	2386	3	Neoplasia	Neoplasia	NNP
cord-022561-rv5j1201	2386	4	.	.	.
cord-022561-rv5j1201	2387	1	Plasma	plasma	NN
cord-022561-rv5j1201	2387	2	cell	cell	NN
cord-022561-rv5j1201	2387	3	neoplasms	neoplasm	NNS
cord-022561-rv5j1201	2387	4	are	be	VBP
cord-022561-rv5j1201	2387	5	most	most	RBS
cord-022561-rv5j1201	2387	6	easily	easily	RB
cord-022561-rv5j1201	2387	7	categorized	categorize	VBN
cord-022561-rv5j1201	2387	8	as	as	IN
cord-022561-rv5j1201	2387	9	myeloma	myeloma	NN
cord-022561-rv5j1201	2387	10	or	or	CC
cord-022561-rv5j1201	2387	11	multiple	multiple	JJ
cord-022561-rv5j1201	2387	12	myeloma	myeloma	NN
cord-022561-rv5j1201	2387	13	,	,	,
cord-022561-rv5j1201	2387	14	which	which	WDT
cord-022561-rv5j1201	2387	15	arises	arise	VBZ
cord-022561-rv5j1201	2387	16	in	in	IN
cord-022561-rv5j1201	2387	17	the	the	DT
cord-022561-rv5j1201	2387	18	bone	bone	NN
cord-022561-rv5j1201	2387	19	marrow	marrow	NN
cord-022561-rv5j1201	2387	20	,	,	,
cord-022561-rv5j1201	2387	21	and	and	CC
cord-022561-rv5j1201	2387	22	extramedullary	extramedullary	NNP
cord-022561-rv5j1201	2387	23	plasmacytoma	plasmacytoma	NNP
cord-022561-rv5j1201	2387	24	,	,	,
cord-022561-rv5j1201	2387	25	which	which	WDT
cord-022561-rv5j1201	2387	26	as	as	IN
cord-022561-rv5j1201	2387	27	the	the	DT
cord-022561-rv5j1201	2387	28	name	name	NN
cord-022561-rv5j1201	2387	29	implies	imply	VBZ
cord-022561-rv5j1201	2387	30	involves	involve	VBZ
cord-022561-rv5j1201	2387	31	sites	site	NNS
cord-022561-rv5j1201	2387	32	other	other	JJ
cord-022561-rv5j1201	2387	33	than	than	IN
cord-022561-rv5j1201	2387	34	bone	bone	NN
cord-022561-rv5j1201	2387	35	.	.	.
cord-022561-rv5j1201	2388	1	Multiple	multiple	JJ
cord-022561-rv5j1201	2388	2	Myeloma	Myeloma	NNP
cord-022561-rv5j1201	2388	3	.	.	.
cord-022561-rv5j1201	2389	1	See	see	VB
cord-022561-rv5j1201	2389	2	Bone	Bone	NNP
cord-022561-rv5j1201	2389	3	Marrow	Marrow	NNP
cord-022561-rv5j1201	2389	4	and	and	CC
cord-022561-rv5j1201	2389	5	Blood	blood	NN
cord-022561-rv5j1201	2389	6	Cells	cell	NNS
cord-022561-rv5j1201	2389	7	,	,	,
cord-022561-rv5j1201	2389	8	Disorders	disorder	NNS
cord-022561-rv5j1201	2389	9	of	of	IN
cord-022561-rv5j1201	2389	10	Domestic	domestic	JJ
cord-022561-rv5j1201	2389	11	Animals	Animals	NNPS
cord-022561-rv5j1201	2389	12	,	,	,
cord-022561-rv5j1201	2389	13	Types	type	NNS
cord-022561-rv5j1201	2389	14	of	of	IN
cord-022561-rv5j1201	2389	15	Hematopoietic	Hematopoietic	NNP
cord-022561-rv5j1201	2389	16	Neoplasia	Neoplasia	NNP
cord-022561-rv5j1201	2389	17	,	,	,
cord-022561-rv5j1201	2389	18	Plasma	plasma	NN
cord-022561-rv5j1201	2389	19	Cell	Cell	NNP
cord-022561-rv5j1201	2389	20	Neoplasia	Neoplasia	NNP
cord-022561-rv5j1201	2389	21	.	.	.
cord-022561-rv5j1201	2390	1	Extramedullary	Extramedullary	NNP
cord-022561-rv5j1201	2390	2	Plasmacytomas	Plasmacytomas	NNP
cord-022561-rv5j1201	2390	3	.	.	.
cord-022561-rv5j1201	2391	1	Extramedullary	Extramedullary	NNP
cord-022561-rv5j1201	2391	2	plasmacytomas	plasmacytoma	NNS
cord-022561-rv5j1201	2391	3	are	be	VBP
cord-022561-rv5j1201	2391	4	most	most	RBS
cord-022561-rv5j1201	2391	5	commonly	commonly	RB
cord-022561-rv5j1201	2391	6	diagnosed	diagnose	VBN
cord-022561-rv5j1201	2391	7	in	in	IN
cord-022561-rv5j1201	2391	8	the	the	DT
cord-022561-rv5j1201	2391	9	skin	skin	NN
cord-022561-rv5j1201	2391	10	of	of	IN
cord-022561-rv5j1201	2391	11	dogs	dog	NNS
cord-022561-rv5j1201	2391	12	(	(	-LRB-
cord-022561-rv5j1201	2391	13	also	also	RB
cord-022561-rv5j1201	2391	14	cats	cat	NNS
cord-022561-rv5j1201	2391	15	and	and	CC
cord-022561-rv5j1201	2391	16	horses	horse	NNS
cord-022561-rv5j1201	2391	17	)	)	-RRB-
cord-022561-rv5j1201	2391	18	,	,	,
cord-022561-rv5j1201	2391	19	where	where	WRB
cord-022561-rv5j1201	2391	20	they	-PRON-	PRP
cord-022561-rv5j1201	2391	21	constitute	constitute	VBP
cord-022561-rv5j1201	2391	22	1.5	1.5	CD
cord-022561-rv5j1201	2391	23	%	%	NN
cord-022561-rv5j1201	2391	24	of	of	IN
cord-022561-rv5j1201	2391	25	all	all	DT
cord-022561-rv5j1201	2391	26	canine	canine	JJ
cord-022561-rv5j1201	2391	27	cutaneous	cutaneous	JJ
cord-022561-rv5j1201	2391	28	tumors	tumor	NNS
cord-022561-rv5j1201	2391	29	(	(	-LRB-
cord-022561-rv5j1201	2391	30	see	see	VB
cord-022561-rv5j1201	2391	31	Chapter	Chapter	NNP
cord-022561-rv5j1201	2391	32	17	17	CD
cord-022561-rv5j1201	2391	33	)	)	-RRB-
cord-022561-rv5j1201	2391	34	.	.	.
cord-022561-rv5j1201	2392	1	The	the	DT
cord-022561-rv5j1201	2392	2	pinnae	pinnae	NN
cord-022561-rv5j1201	2392	3	,	,	,
cord-022561-rv5j1201	2392	4	lips	lip	NNS
cord-022561-rv5j1201	2392	5	,	,	,
cord-022561-rv5j1201	2392	6	digits	digit	NNS
cord-022561-rv5j1201	2392	7	,	,	,
cord-022561-rv5j1201	2392	8	and	and	CC
cord-022561-rv5j1201	2392	9	chin	chin	NNP
cord-022561-rv5j1201	2392	10	are	be	VBP
cord-022561-rv5j1201	2392	11	the	the	DT
cord-022561-rv5j1201	2392	12	most	most	RBS
cord-022561-rv5j1201	2392	13	commonly	commonly	RB
cord-022561-rv5j1201	2392	14	affected	affect	VBN
cord-022561-rv5j1201	2392	15	locations	location	NNS
cord-022561-rv5j1201	2392	16	,	,	,
cord-022561-rv5j1201	2392	17	and	and	CC
cord-022561-rv5j1201	2392	18	most	most	JJS
cord-022561-rv5j1201	2392	19	lesions	lesion	NNS
cord-022561-rv5j1201	2392	20	are	be	VBP
cord-022561-rv5j1201	2392	21	solitary	solitary	JJ
cord-022561-rv5j1201	2392	22	,	,	,
cord-022561-rv5j1201	2392	23	though	though	IN
cord-022561-rv5j1201	2392	24	multiple	multiple	JJ
cord-022561-rv5j1201	2392	25	plasmacytomas	plasmacytoma	NNS
cord-022561-rv5j1201	2392	26	are	be	VBP
cord-022561-rv5j1201	2392	27	infrequently	infrequently	RB
cord-022561-rv5j1201	2392	28	diagnosed	diagnose	VBN
cord-022561-rv5j1201	2392	29	.	.	.
cord-022561-rv5j1201	2393	1	Other	other	JJ
cord-022561-rv5j1201	2393	2	tissues	tissue	NNS
cord-022561-rv5j1201	2393	3	affected	affect	VBN
cord-022561-rv5j1201	2393	4	include	include	VBP
cord-022561-rv5j1201	2393	5	the	the	DT
cord-022561-rv5j1201	2393	6	oral	oral	JJ
cord-022561-rv5j1201	2393	7	cavity	cavity	NN
cord-022561-rv5j1201	2393	8	,	,	,
cord-022561-rv5j1201	2393	9	intestine	intestine	NN
cord-022561-rv5j1201	2393	10	(	(	-LRB-
cord-022561-rv5j1201	2393	11	colorectal	colorectal	NN
cord-022561-rv5j1201	2393	12	in	in	IN
cord-022561-rv5j1201	2393	13	particular	particular	JJ
cord-022561-rv5j1201	2393	14	)	)	-RRB-
cord-022561-rv5j1201	2393	15	,	,	,
cord-022561-rv5j1201	2393	16	liver	liver	NN
cord-022561-rv5j1201	2393	17	,	,	,
cord-022561-rv5j1201	2393	18	spleen	spleen	NN
cord-022561-rv5j1201	2393	19	,	,	,
cord-022561-rv5j1201	2393	20	kidney	kidney	NN
cord-022561-rv5j1201	2393	21	,	,	,
cord-022561-rv5j1201	2393	22	lung	lung	NN
cord-022561-rv5j1201	2393	23	,	,	,
cord-022561-rv5j1201	2393	24	and	and	CC
cord-022561-rv5j1201	2393	25	brain	brain	NN
cord-022561-rv5j1201	2393	26	;	;	:
cord-022561-rv5j1201	2393	27	of	of	IN
cord-022561-rv5j1201	2393	28	these	these	DT
cord-022561-rv5j1201	2393	29	,	,	,
cord-022561-rv5j1201	2393	30	the	the	DT
cord-022561-rv5j1201	2393	31	oral	oral	JJ
cord-022561-rv5j1201	2393	32	cavity	cavity	NN
cord-022561-rv5j1201	2393	33	and	and	CC
cord-022561-rv5j1201	2393	34	intestine	intestine	NN
cord-022561-rv5j1201	2393	35	(	(	-LRB-
cord-022561-rv5j1201	2393	36	colorectal	colorectal	NN
cord-022561-rv5j1201	2393	37	)	)	-RRB-
cord-022561-rv5j1201	2393	38	are	be	VBP
cord-022561-rv5j1201	2393	39	involved	involve	VBN
cord-022561-rv5j1201	2393	40	most	most	RBS
cord-022561-rv5j1201	2393	41	often	often	RB
cord-022561-rv5j1201	2393	42	.	.	.
cord-022561-rv5j1201	2394	1	In	in	IN
cord-022561-rv5j1201	2394	2	one	one	CD
cord-022561-rv5j1201	2394	3	study	study	NN
cord-022561-rv5j1201	2394	4	,	,	,
cord-022561-rv5j1201	2394	5	extramedullary	extramedullary	NNP
cord-022561-rv5j1201	2394	6	plasmacytomas	plasmacytomas	NNP
cord-022561-rv5j1201	2394	7	represented	represent	VBD
cord-022561-rv5j1201	2394	8	5	5	CD
cord-022561-rv5j1201	2394	9	%	%	NN
cord-022561-rv5j1201	2394	10	of	of	IN
cord-022561-rv5j1201	2394	11	all	all	DT
cord-022561-rv5j1201	2394	12	canine	canine	JJ
cord-022561-rv5j1201	2394	13	oral	oral	JJ
cord-022561-rv5j1201	2394	14	tumors	tumor	NNS
cord-022561-rv5j1201	2394	15	and	and	CC
cord-022561-rv5j1201	2394	16	28	28	CD
cord-022561-rv5j1201	2394	17	%	%	NN
cord-022561-rv5j1201	2394	18	of	of	IN
cord-022561-rv5j1201	2394	19	all	all	DT
cord-022561-rv5j1201	2394	20	extramedullary	extramedullary	NNP
cord-022561-rv5j1201	2394	21	plasmacytomas	plasmacytomas	NNP
cord-022561-rv5j1201	2394	22	diagnosed	diagnose	VBN
cord-022561-rv5j1201	2394	23	.	.	.
cord-022561-rv5j1201	2395	1	Most	Most	JJS
cord-022561-rv5j1201	2395	2	cutaneous	cutaneous	JJ
cord-022561-rv5j1201	2395	3	extramedullary	extramedullary	JJ
cord-022561-rv5j1201	2395	4	plasmacytomas	plasmacytoma	NNS
cord-022561-rv5j1201	2395	5	are	be	VBP
cord-022561-rv5j1201	2395	6	benign	benign	JJ
cord-022561-rv5j1201	2395	7	,	,	,
cord-022561-rv5j1201	2395	8	and	and	CC
cord-022561-rv5j1201	2395	9	complete	complete	JJ
cord-022561-rv5j1201	2395	10	excision	excision	NN
cord-022561-rv5j1201	2395	11	is	be	VBZ
cord-022561-rv5j1201	2395	12	usually	usually	RB
cord-022561-rv5j1201	2395	13	curative	curative	JJ
cord-022561-rv5j1201	2395	14	;	;	:
cord-022561-rv5j1201	2395	15	oral	oral	JJ
cord-022561-rv5j1201	2395	16	cavity	cavity	NN
cord-022561-rv5j1201	2395	17	and	and	CC
cord-022561-rv5j1201	2395	18	colorectal	colorectal	JJ
cord-022561-rv5j1201	2395	19	extramedullary	extramedullary	JJ
cord-022561-rv5j1201	2395	20	plasmacytomas	plasmacytomas	NNPS
cord-022561-rv5j1201	2395	21	are	be	VBP
cord-022561-rv5j1201	2395	22	likely	likely	JJ
cord-022561-rv5j1201	2395	23	to	to	TO
cord-022561-rv5j1201	2395	24	behave	behave	VB
cord-022561-rv5j1201	2395	25	in	in	IN
cord-022561-rv5j1201	2395	26	a	a	DT
cord-022561-rv5j1201	2395	27	similar	similar	JJ
cord-022561-rv5j1201	2395	28	manner	manner	NN
cord-022561-rv5j1201	2395	29	.	.	.
cord-022561-rv5j1201	2396	1	More	more	RBR
cord-022561-rv5j1201	2396	2	aggressive	aggressive	JJ
cord-022561-rv5j1201	2396	3	forms	form	NNS
cord-022561-rv5j1201	2396	4	may	may	MD
cord-022561-rv5j1201	2396	5	occur	occur	VB
cord-022561-rv5j1201	2396	6	at	at	IN
cord-022561-rv5j1201	2396	7	any	any	DT
cord-022561-rv5j1201	2396	8	site	site	NN
cord-022561-rv5j1201	2396	9	.	.	.
cord-022561-rv5j1201	2397	1	As	as	IN
cord-022561-rv5j1201	2397	2	with	with	IN
cord-022561-rv5j1201	2397	3	multiple	multiple	JJ
cord-022561-rv5j1201	2397	4	myeloma	myeloma	NN
cord-022561-rv5j1201	2397	5	,	,	,
cord-022561-rv5j1201	2397	6	the	the	DT
cord-022561-rv5j1201	2397	7	neoplastic	neoplastic	JJ
cord-022561-rv5j1201	2397	8	cells	cell	NNS
cord-022561-rv5j1201	2397	9	composing	compose	VBG
cord-022561-rv5j1201	2397	10	the	the	DT
cord-022561-rv5j1201	2397	11	tumor	tumor	NN
cord-022561-rv5j1201	2397	12	may	may	MD
cord-022561-rv5j1201	2397	13	vary	vary	VB
cord-022561-rv5j1201	2397	14	from	from	IN
cord-022561-rv5j1201	2397	15	well	well	RB
cord-022561-rv5j1201	2397	16	differentiated	differentiated	JJ
cord-022561-rv5j1201	2397	17	to	to	IN
cord-022561-rv5j1201	2397	18	pleomorphic	pleomorphic	JJ
cord-022561-rv5j1201	2397	19	,	,	,
cord-022561-rv5j1201	2397	20	often	often	RB
cord-022561-rv5j1201	2397	21	within	within	IN
cord-022561-rv5j1201	2397	22	the	the	DT
cord-022561-rv5j1201	2397	23	same	same	JJ
cord-022561-rv5j1201	2397	24	tumor	tumor	NN
cord-022561-rv5j1201	2397	25	.	.	.
cord-022561-rv5j1201	2398	1	The	the	DT
cord-022561-rv5j1201	2398	2	cells	cell	NNS
cord-022561-rv5j1201	2398	3	often	often	RB
cord-022561-rv5j1201	2398	4	have	have	VBP
cord-022561-rv5j1201	2398	5	a	a	DT
cord-022561-rv5j1201	2398	6	characteristic	characteristic	JJ
cord-022561-rv5j1201	2398	7	perinuclear	perinuclear	NN
cord-022561-rv5j1201	2398	8	Golgi	Golgi	NNP
cord-022561-rv5j1201	2398	9	clearing	clearing	NN
cord-022561-rv5j1201	2398	10	or	or	CC
cord-022561-rv5j1201	2398	11	"	"	``
cord-022561-rv5j1201	2398	12	halo	halo	NN
cord-022561-rv5j1201	2398	13	,	,	,
cord-022561-rv5j1201	2398	14	"	"	''
cord-022561-rv5j1201	2398	15	and	and	CC
cord-022561-rv5j1201	2398	16	the	the	DT
cord-022561-rv5j1201	2398	17	more	more	RBR
cord-022561-rv5j1201	2398	18	pleomorphic	pleomorphic	JJ
cord-022561-rv5j1201	2398	19	cells	cell	NNS
cord-022561-rv5j1201	2398	20	exhibit	exhibit	VBP
cord-022561-rv5j1201	2398	21	karyomegaly	karyomegaly	NNP
cord-022561-rv5j1201	2398	22	and	and	CC
cord-022561-rv5j1201	2398	23	binucleation	binucleation	NNP
cord-022561-rv5j1201	2398	24	(	(	-LRB-
cord-022561-rv5j1201	2398	25	Fig	Fig	NNP
cord-022561-rv5j1201	2398	26	.	.	.
cord-022561-rv5j1201	2398	27	13	13	CD
cord-022561-rv5j1201	2398	28	-	-	SYM
cord-022561-rv5j1201	2398	29	84	84	CD
cord-022561-rv5j1201	2398	30	)	)	-RRB-
cord-022561-rv5j1201	2398	31	.	.	.
cord-022561-rv5j1201	2399	1	Extramedullary	Extramedullary	NNP
cord-022561-rv5j1201	2399	2	plasmacytomas	plasmacytomas	NN
cord-022561-rv5j1201	2399	3	may	may	MD
cord-022561-rv5j1201	2399	4	produce	produce	VB
cord-022561-rv5j1201	2399	5	monoclonal	monoclonal	JJ
cord-022561-rv5j1201	2399	6	immunoglobulins	immunoglobulin	NNS
cord-022561-rv5j1201	2399	7	with	with	IN
cord-022561-rv5j1201	2399	8	resulting	result	VBG
cord-022561-rv5j1201	2399	9	monoclonal	monoclonal	JJ
cord-022561-rv5j1201	2399	10	gammopathy	gammopathy	NN
cord-022561-rv5j1201	2399	11	.	.	.
cord-022561-rv5j1201	2400	1	Amyloid	amyloid	NN
cord-022561-rv5j1201	2400	2	deposition	deposition	NN
cord-022561-rv5j1201	2400	3	(	(	-LRB-
cord-022561-rv5j1201	2400	4	which	which	WDT
cord-022561-rv5j1201	2400	5	may	may	MD
cord-022561-rv5j1201	2400	6	mineralize	mineralize	VB
cord-022561-rv5j1201	2400	7	)	)	-RRB-
cord-022561-rv5j1201	2400	8	is	be	VBZ
cord-022561-rv5j1201	2400	9	also	also	RB
cord-022561-rv5j1201	2400	10	observed	observe	VBN
cord-022561-rv5j1201	2400	11	in	in	IN
cord-022561-rv5j1201	2400	12	a	a	DT
cord-022561-rv5j1201	2400	13	proportion	proportion	NN
cord-022561-rv5j1201	2400	14	of	of	IN
cord-022561-rv5j1201	2400	15	cases	case	NNS
cord-022561-rv5j1201	2400	16	.	.	.
cord-022561-rv5j1201	2401	1	Differentiation	differentiation	NN
cord-022561-rv5j1201	2401	2	from	from	IN
cord-022561-rv5j1201	2401	3	other	other	JJ
cord-022561-rv5j1201	2401	4	round	round	JJ
cord-022561-rv5j1201	2401	5	cell	cell	NN
cord-022561-rv5j1201	2401	6	tumors	tumor	NNS
cord-022561-rv5j1201	2401	7	may	may	MD
cord-022561-rv5j1201	2401	8	be	be	VB
cord-022561-rv5j1201	2401	9	aided	aid	VBN
cord-022561-rv5j1201	2401	10	by	by	IN
cord-022561-rv5j1201	2401	11	Severe	severe	JJ
cord-022561-rv5j1201	2401	12	combined	combined	JJ
cord-022561-rv5j1201	2401	13	immunodeficiency	immunodeficiency	NN
cord-022561-rv5j1201	2401	14	disease	disease	NN
cord-022561-rv5j1201	2401	15	of	of	IN
cord-022561-rv5j1201	2401	16	Arabian	arabian	JJ
cord-022561-rv5j1201	2401	17	foals	foal	NNS
cord-022561-rv5j1201	2401	18	is	be	VBZ
cord-022561-rv5j1201	2401	19	an	an	DT
cord-022561-rv5j1201	2401	20	autosomal	autosomal	JJ
cord-022561-rv5j1201	2401	21	recessive	recessive	JJ
cord-022561-rv5j1201	2401	22	primary	primary	JJ
cord-022561-rv5j1201	2401	23	immunodeficiency	immunodeficiency	NN
cord-022561-rv5j1201	2401	24	disorder	disorder	NN
cord-022561-rv5j1201	2401	25	characterized	characterize	VBN
cord-022561-rv5j1201	2401	26	by	by	IN
cord-022561-rv5j1201	2401	27	the	the	DT
cord-022561-rv5j1201	2401	28	lack	lack	NN
cord-022561-rv5j1201	2401	29	of	of	IN
cord-022561-rv5j1201	2401	30	functional	functional	JJ
cord-022561-rv5j1201	2401	31	T	t	NN
cord-022561-rv5j1201	2401	32	and	and	CC
cord-022561-rv5j1201	2401	33	B	b	NN
cord-022561-rv5j1201	2401	34	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	2401	35	caused	cause	VBN
cord-022561-rv5j1201	2401	36	by	by	IN
cord-022561-rv5j1201	2401	37	a	a	DT
cord-022561-rv5j1201	2401	38	genetic	genetic	JJ
cord-022561-rv5j1201	2401	39	mutation	mutation	NN
cord-022561-rv5j1201	2401	40	in	in	IN
cord-022561-rv5j1201	2401	41	the	the	DT
cord-022561-rv5j1201	2401	42	gene	gene	NN
cord-022561-rv5j1201	2401	43	encoding	encoding	NN
cord-022561-rv5j1201	2401	44	for	for	IN
cord-022561-rv5j1201	2401	45	DNA	dna	NN
cord-022561-rv5j1201	2401	46	-	-	HYPH
cord-022561-rv5j1201	2401	47	dependent	dependent	JJ
cord-022561-rv5j1201	2401	48	protein	protein	NN
cord-022561-rv5j1201	2401	49	kinase	kinase	NN
cord-022561-rv5j1201	2401	50	catalytic	catalytic	JJ
cord-022561-rv5j1201	2401	51	subunit	subunit	NN
cord-022561-rv5j1201	2401	52	(	(	-LRB-
cord-022561-rv5j1201	2401	53	DNA	DNA	NNP
cord-022561-rv5j1201	2401	54	-	-	HYPH
cord-022561-rv5j1201	2401	55	PKcs	PKcs	NNP
cord-022561-rv5j1201	2401	56	)	)	-RRB-
cord-022561-rv5j1201	2401	57	.	.	.
cord-022561-rv5j1201	2402	1	This	this	DT
cord-022561-rv5j1201	2402	2	enzyme	enzyme	NN
cord-022561-rv5j1201	2402	3	is	be	VBZ
cord-022561-rv5j1201	2402	4	required	require	VBN
cord-022561-rv5j1201	2402	5	for	for	IN
cord-022561-rv5j1201	2402	6	receptor	receptor	NN
cord-022561-rv5j1201	2402	7	gene	gene	NN
cord-022561-rv5j1201	2402	8	rearrangements	rearrangement	NNS
cord-022561-rv5j1201	2402	9	involved	involve	VBN
cord-022561-rv5j1201	2402	10	in	in	IN
cord-022561-rv5j1201	2402	11	the	the	DT
cord-022561-rv5j1201	2402	12	maturation	maturation	NN
cord-022561-rv5j1201	2402	13	of	of	IN
cord-022561-rv5j1201	2402	14	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	2402	15	,	,	,
cord-022561-rv5j1201	2402	16	and	and	CC
cord-022561-rv5j1201	2402	17	the	the	DT
cord-022561-rv5j1201	2402	18	resulting	result	VBG
cord-022561-rv5j1201	2402	19	loss	loss	NN
cord-022561-rv5j1201	2402	20	of	of	IN
cord-022561-rv5j1201	2402	21	functional	functional	JJ
cord-022561-rv5j1201	2402	22	T	t	NN
cord-022561-rv5j1201	2402	23	and	and	CC
cord-022561-rv5j1201	2402	24	B	b	NN
cord-022561-rv5j1201	2402	25	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	2402	26	leads	lead	VBZ
cord-022561-rv5j1201	2402	27	to	to	IN
cord-022561-rv5j1201	2402	28	a	a	DT
cord-022561-rv5j1201	2402	29	profound	profound	JJ
cord-022561-rv5j1201	2402	30	susceptibility	susceptibility	NN
cord-022561-rv5j1201	2402	31	to	to	IN
cord-022561-rv5j1201	2402	32	infectious	infectious	JJ
cord-022561-rv5j1201	2402	33	diseases	disease	NNS
cord-022561-rv5j1201	2402	34	.	.	.
cord-022561-rv5j1201	2403	1	Though	though	IN
cord-022561-rv5j1201	2403	2	normal	normal	JJ
cord-022561-rv5j1201	2403	3	at	at	IN
cord-022561-rv5j1201	2403	4	birth	birth	NN
cord-022561-rv5j1201	2403	5	,	,	,
cord-022561-rv5j1201	2403	6	these	these	DT
cord-022561-rv5j1201	2403	7	foals	foal	NNS
cord-022561-rv5j1201	2403	8	develop	develop	VBP
cord-022561-rv5j1201	2403	9	diarrhea	diarrhea	NN
cord-022561-rv5j1201	2403	10	and	and	CC
cord-022561-rv5j1201	2403	11	pneumonia	pneumonia	NN
cord-022561-rv5j1201	2403	12	by	by	IN
cord-022561-rv5j1201	2403	13	approximately	approximately	RB
cord-022561-rv5j1201	2403	14	10	10	CD
cord-022561-rv5j1201	2403	15	days	day	NNS
cord-022561-rv5j1201	2403	16	of	of	IN
cord-022561-rv5j1201	2403	17	age	age	NN
cord-022561-rv5j1201	2403	18	,	,	,
cord-022561-rv5j1201	2403	19	often	often	RB
cord-022561-rv5j1201	2403	20	due	due	JJ
cord-022561-rv5j1201	2403	21	to	to	IN
cord-022561-rv5j1201	2403	22	adenovirus	adenovirus	NN
cord-022561-rv5j1201	2403	23	,	,	,
cord-022561-rv5j1201	2403	24	Cryptosporidium	cryptosporidium	NN
cord-022561-rv5j1201	2403	25	parvum	parvum	NN
cord-022561-rv5j1201	2403	26	,	,	,
cord-022561-rv5j1201	2403	27	and	and	CC
cord-022561-rv5j1201	2403	28	Pneumocystis	Pneumocystis	NNP
cord-022561-rv5j1201	2403	29	carinii	carinii	FW
cord-022561-rv5j1201	2403	30	infections	infection	NNS
cord-022561-rv5j1201	2403	31	.	.	.
cord-022561-rv5j1201	2404	1	Affected	affected	JJ
cord-022561-rv5j1201	2404	2	foals	foal	NNS
cord-022561-rv5j1201	2404	3	often	often	RB
cord-022561-rv5j1201	2404	4	die	die	VBP
cord-022561-rv5j1201	2404	5	before	before	IN
cord-022561-rv5j1201	2404	6	5	5	CD
cord-022561-rv5j1201	2404	7	months	month	NNS
cord-022561-rv5j1201	2404	8	of	of	IN
cord-022561-rv5j1201	2404	9	age	age	NN
cord-022561-rv5j1201	2404	10	.	.	.
cord-022561-rv5j1201	2405	1	Lymph	lymph	NN
cord-022561-rv5j1201	2405	2	nodes	node	NNS
cord-022561-rv5j1201	2405	3	and	and	CC
cord-022561-rv5j1201	2405	4	thymus	thymus	NN
cord-022561-rv5j1201	2405	5	are	be	VBP
cord-022561-rv5j1201	2405	6	small	small	JJ
cord-022561-rv5j1201	2405	7	and	and	CC
cord-022561-rv5j1201	2405	8	often	often	RB
cord-022561-rv5j1201	2405	9	grossly	grossly	RB
cord-022561-rv5j1201	2405	10	undetectable	undetectable	JJ
cord-022561-rv5j1201	2405	11	,	,	,
cord-022561-rv5j1201	2405	12	and	and	CC
cord-022561-rv5j1201	2405	13	the	the	DT
cord-022561-rv5j1201	2405	14	spleen	spleen	NN
cord-022561-rv5j1201	2405	15	is	be	VBZ
cord-022561-rv5j1201	2405	16	small	small	JJ
cord-022561-rv5j1201	2405	17	and	and	CC
cord-022561-rv5j1201	2405	18	firm	firm	JJ
cord-022561-rv5j1201	2405	19	due	due	IN
cord-022561-rv5j1201	2405	20	to	to	IN
cord-022561-rv5j1201	2405	21	the	the	DT
cord-022561-rv5j1201	2405	22	absence	absence	NN
cord-022561-rv5j1201	2405	23	of	of	IN
cord-022561-rv5j1201	2405	24	white	white	JJ
cord-022561-rv5j1201	2405	25	pulp	pulp	NN
cord-022561-rv5j1201	2405	26	(	(	-LRB-
cord-022561-rv5j1201	2405	27	see	see	VB
cord-022561-rv5j1201	2405	28	Fig	Fig	NNP
cord-022561-rv5j1201	2405	29	.	.	.
cord-022561-rv5j1201	2406	1	13	13	CD
cord-022561-rv5j1201	2406	2	-	-	SYM
cord-022561-rv5j1201	2406	3	70	70	CD
cord-022561-rv5j1201	2406	4	)	)	-RRB-
cord-022561-rv5j1201	2406	5	.	.	.
cord-022561-rv5j1201	2407	1	The	the	DT
cord-022561-rv5j1201	2407	2	development	development	NN
cord-022561-rv5j1201	2407	3	of	of	IN
cord-022561-rv5j1201	2407	4	genetic	genetic	JJ
cord-022561-rv5j1201	2407	5	tests	test	NNS
cord-022561-rv5j1201	2407	6	to	to	TO
cord-022561-rv5j1201	2407	7	identify	identify	VB
cord-022561-rv5j1201	2407	8	carriers	carrier	NNS
cord-022561-rv5j1201	2407	9	of	of	IN
cord-022561-rv5j1201	2407	10	the	the	DT
cord-022561-rv5j1201	2407	11	disorder	disorder	NN
cord-022561-rv5j1201	2407	12	has	have	VBZ
cord-022561-rv5j1201	2407	13	led	lead	VBN
cord-022561-rv5j1201	2407	14	to	to	IN
cord-022561-rv5j1201	2407	15	a	a	DT
cord-022561-rv5j1201	2407	16	decrease	decrease	NN
cord-022561-rv5j1201	2407	17	in	in	IN
cord-022561-rv5j1201	2407	18	the	the	DT
cord-022561-rv5j1201	2407	19	prevalence	prevalence	NN
cord-022561-rv5j1201	2407	20	of	of	IN
cord-022561-rv5j1201	2407	21	severe	severe	JJ
cord-022561-rv5j1201	2407	22	combined	combine	VBN
cord-022561-rv5j1201	2407	23	immunodeficiency	immunodeficiency	NN
cord-022561-rv5j1201	2407	24	disease	disease	NN
cord-022561-rv5j1201	2407	25	.	.	.
cord-022561-rv5j1201	2408	1	Recently	recently	RB
cord-022561-rv5j1201	2408	2	,	,	,
cord-022561-rv5j1201	2408	3	severe	severe	JJ
cord-022561-rv5j1201	2408	4	combined	combine	VBN
cord-022561-rv5j1201	2408	5	immunodeficiency	immunodeficiency	NN
cord-022561-rv5j1201	2408	6	disease	disease	NN
cord-022561-rv5j1201	2408	7	was	be	VBD
cord-022561-rv5j1201	2408	8	diagnosed	diagnose	VBN
cord-022561-rv5j1201	2408	9	in	in	IN
cord-022561-rv5j1201	2408	10	a	a	DT
cord-022561-rv5j1201	2408	11	single	single	JJ
cord-022561-rv5j1201	2408	12	Caspian	Caspian	NNP
cord-022561-rv5j1201	2408	13	filly	filly	NN
cord-022561-rv5j1201	2408	14	,	,	,
cord-022561-rv5j1201	2408	15	though	though	IN
cord-022561-rv5j1201	2408	16	the	the	DT
cord-022561-rv5j1201	2408	17	exact	exact	JJ
cord-022561-rv5j1201	2408	18	genetic	genetic	JJ
cord-022561-rv5j1201	2408	19	defect	defect	NN
cord-022561-rv5j1201	2408	20	was	be	VBD
cord-022561-rv5j1201	2408	21	not	not	RB
cord-022561-rv5j1201	2408	22	determined	determine	VBN
cord-022561-rv5j1201	2408	23	.	.	.
cord-022561-rv5j1201	2409	1	Congenital	congenital	JJ
cord-022561-rv5j1201	2409	2	immunodeficiency	immunodeficiency	NN
cord-022561-rv5j1201	2409	3	diseases	disease	NNS
cord-022561-rv5j1201	2409	4	are	be	VBP
cord-022561-rv5j1201	2409	5	also	also	RB
cord-022561-rv5j1201	2409	6	discussed	discuss	VBN
cord-022561-rv5j1201	2409	7	in	in	IN
cord-022561-rv5j1201	2409	8	detail	detail	NN
cord-022561-rv5j1201	2409	9	in	in	IN
cord-022561-rv5j1201	2409	10	Chapter	chapter	NN
cord-022561-rv5j1201	2409	11	5	5	CD
cord-022561-rv5j1201	2409	12	.	.	.
cord-022561-rv5j1201	2410	1	Streptococcus	streptococcus	NN
cord-022561-rv5j1201	2410	2	equi	equi	NN
cord-022561-rv5j1201	2410	3	ssp	ssp	NN
cord-022561-rv5j1201	2410	4	.	.	.
cord-022561-rv5j1201	2410	5	equi	equi	NNP
cord-022561-rv5j1201	2410	6	,	,	,
cord-022561-rv5j1201	2410	7	the	the	DT
cord-022561-rv5j1201	2410	8	etiologic	etiologic	JJ
cord-022561-rv5j1201	2410	9	agent	agent	NN
cord-022561-rv5j1201	2410	10	of	of	IN
cord-022561-rv5j1201	2410	11	equine	equine	JJ
cord-022561-rv5j1201	2410	12	strangles	strangle	NNS
cord-022561-rv5j1201	2410	13	,	,	,
cord-022561-rv5j1201	2410	14	is	be	VBZ
cord-022561-rv5j1201	2410	15	inhaled	inhale	VBN
cord-022561-rv5j1201	2410	16	or	or	CC
cord-022561-rv5j1201	2410	17	ingested	ingest	VBN
cord-022561-rv5j1201	2410	18	after	after	IN
cord-022561-rv5j1201	2410	19	direct	direct	JJ
cord-022561-rv5j1201	2410	20	contact	contact	NN
cord-022561-rv5j1201	2410	21	with	with	IN
cord-022561-rv5j1201	2410	22	the	the	DT
cord-022561-rv5j1201	2410	23	discharge	discharge	NN
cord-022561-rv5j1201	2410	24	from	from	IN
cord-022561-rv5j1201	2410	25	infected	infected	JJ
cord-022561-rv5j1201	2410	26	horses	horse	NNS
cord-022561-rv5j1201	2410	27	or	or	CC
cord-022561-rv5j1201	2410	28	from	from	IN
cord-022561-rv5j1201	2410	29	a	a	DT
cord-022561-rv5j1201	2410	30	contaminated	contaminate	VBN
cord-022561-rv5j1201	2410	31	environment	environment	NN
cord-022561-rv5j1201	2410	32	.	.	.
cord-022561-rv5j1201	2411	1	The	the	DT
cord-022561-rv5j1201	2411	2	bacteria	bacteria	NNS
cord-022561-rv5j1201	2411	3	attach	attach	VBP
cord-022561-rv5j1201	2411	4	to	to	IN
cord-022561-rv5j1201	2411	5	the	the	DT
cord-022561-rv5j1201	2411	6	tonsils	tonsil	NNS
cord-022561-rv5j1201	2411	7	,	,	,
cord-022561-rv5j1201	2411	8	penetrate	penetrate	VB
cord-022561-rv5j1201	2411	9	into	into	IN
cord-022561-rv5j1201	2411	10	deeper	deep	JJR
cord-022561-rv5j1201	2411	11	tissues	tissue	NNS
cord-022561-rv5j1201	2411	12	,	,	,
cord-022561-rv5j1201	2411	13	enter	enter	VB
cord-022561-rv5j1201	2411	14	the	the	DT
cord-022561-rv5j1201	2411	15	lymphatic	lymphatic	JJ
cord-022561-rv5j1201	2411	16	vessels	vessel	NNS
cord-022561-rv5j1201	2411	17	,	,	,
cord-022561-rv5j1201	2411	18	drain	drain	VB
cord-022561-rv5j1201	2411	19	to	to	IN
cord-022561-rv5j1201	2411	20	regional	regional	JJ
cord-022561-rv5j1201	2411	21	lymph	lymph	NN
cord-022561-rv5j1201	2411	22	nodes	node	NNS
cord-022561-rv5j1201	2411	23	(	(	-LRB-
cord-022561-rv5j1201	2411	24	mandibular	mandibular	JJ
cord-022561-rv5j1201	2411	25	,	,	,
cord-022561-rv5j1201	2411	26	retropharyngeal	retropharyngeal	NN
cord-022561-rv5j1201	2411	27	,	,	,
cord-022561-rv5j1201	2411	28	and	and	CC
cord-022561-rv5j1201	2411	29	occasionally	occasionally	RB
cord-022561-rv5j1201	2411	30	parotid	parotid	JJ
cord-022561-rv5j1201	2411	31	and	and	CC
cord-022561-rv5j1201	2411	32	cervical	cervical	JJ
cord-022561-rv5j1201	2411	33	lymph	lymph	NN
cord-022561-rv5j1201	2411	34	nodes	node	NNS
cord-022561-rv5j1201	2411	35	)	)	-RRB-
cord-022561-rv5j1201	2411	36	,	,	,
cord-022561-rv5j1201	2411	37	and	and	CC
cord-022561-rv5j1201	2411	38	cause	cause	VB
cord-022561-rv5j1201	2411	39	large	large	JJ
cord-022561-rv5j1201	2411	40	abscesses	abscess	NNS
cord-022561-rv5j1201	2411	41	(	(	-LRB-
cord-022561-rv5j1201	2411	42	see	see	VB
cord-022561-rv5j1201	2411	43	Fig	Fig	NNP
cord-022561-rv5j1201	2411	44	.	.	.
cord-022561-rv5j1201	2411	45	13	13	CD
cord-022561-rv5j1201	2411	46	-77	-77	CD
cord-022561-rv5j1201	2411	47	)	)	-RRB-
cord-022561-rv5j1201	2411	48	.	.	.
cord-022561-rv5j1201	2412	1	Retropharyngeal	retropharyngeal	JJ
cord-022561-rv5j1201	2412	2	enlargement	enlargement	NN
cord-022561-rv5j1201	2412	3	from	from	IN
cord-022561-rv5j1201	2412	4	abscesses	abscess	NNS
cord-022561-rv5j1201	2412	5	may	may	MD
cord-022561-rv5j1201	2412	6	lead	lead	VB
cord-022561-rv5j1201	2412	7	to	to	IN
cord-022561-rv5j1201	2412	8	compression	compression	NN
cord-022561-rv5j1201	2412	9	of	of	IN
cord-022561-rv5j1201	2412	10	the	the	DT
cord-022561-rv5j1201	2412	11	pharynx	pharynx	NN
cord-022561-rv5j1201	2412	12	and	and	CC
cord-022561-rv5j1201	2412	13	subsequent	subsequent	JJ
cord-022561-rv5j1201	2412	14	respiratory	respiratory	JJ
cord-022561-rv5j1201	2412	15	stridor	stridor	NNS
cord-022561-rv5j1201	2412	16	and	and	CC
cord-022561-rv5j1201	2412	17	dysphagia	dysphagia	NN
cord-022561-rv5j1201	2412	18	.	.	.
cord-022561-rv5j1201	2413	1	Abscesses	abscess	NNS
cord-022561-rv5j1201	2413	2	may	may	MD
cord-022561-rv5j1201	2413	3	rupture	rupture	VB
cord-022561-rv5j1201	2413	4	and	and	CC
cord-022561-rv5j1201	2413	5	discharge	discharge	NN
cord-022561-rv5j1201	2413	6	pus	pus	NN
cord-022561-rv5j1201	2413	7	through	through	IN
cord-022561-rv5j1201	2413	8	a	a	DT
cord-022561-rv5j1201	2413	9	sinus	sinus	NN
cord-022561-rv5j1201	2413	10	to	to	IN
cord-022561-rv5j1201	2413	11	the	the	DT
cord-022561-rv5j1201	2413	12	skin	skin	NN
cord-022561-rv5j1201	2413	13	surface	surface	NN
cord-022561-rv5j1201	2413	14	or	or	CC
cord-022561-rv5j1201	2413	15	spread	spread	VB
cord-022561-rv5j1201	2413	16	medially	medially	RB
cord-022561-rv5j1201	2413	17	into	into	IN
cord-022561-rv5j1201	2413	18	guttural	guttural	JJ
cord-022561-rv5j1201	2413	19	pouches	pouch	NNS
cord-022561-rv5j1201	2413	20	,	,	,
cord-022561-rv5j1201	2413	21	where	where	WRB
cord-022561-rv5j1201	2413	22	residual	residual	JJ
cord-022561-rv5j1201	2413	23	pus	pus	NN
cord-022561-rv5j1201	2413	24	dries	dry	VBZ
cord-022561-rv5j1201	2413	25	and	and	CC
cord-022561-rv5j1201	2413	26	hardens	harden	VBZ
cord-022561-rv5j1201	2413	27	to	to	TO
cord-022561-rv5j1201	2413	28	form	form	VB
cord-022561-rv5j1201	2413	29	chondroids	chondroid	NNS
cord-022561-rv5j1201	2413	30	(	(	-LRB-
cord-022561-rv5j1201	2413	31	which	which	WDT
cord-022561-rv5j1201	2413	32	serve	serve	VBP
cord-022561-rv5j1201	2413	33	as	as	IN
cord-022561-rv5j1201	2413	34	a	a	DT
cord-022561-rv5j1201	2413	35	nidus	nidus	NN
cord-022561-rv5j1201	2413	36	for	for	IN
cord-022561-rv5j1201	2413	37	live	live	JJ
cord-022561-rv5j1201	2413	38	bacteria	bacteria	NNS
cord-022561-rv5j1201	2413	39	to	to	TO
cord-022561-rv5j1201	2413	40	persist	persist	VB
cord-022561-rv5j1201	2413	41	in	in	IN
cord-022561-rv5j1201	2413	42	carrier	carrier	NN
cord-022561-rv5j1201	2413	43	animals	animal	NNS
cord-022561-rv5j1201	2413	44	)	)	-RRB-
cord-022561-rv5j1201	2413	45	.	.	.
cord-022561-rv5j1201	2414	1	In	in	IN
cord-022561-rv5j1201	2414	2	up	up	IN
cord-022561-rv5j1201	2414	3	to	to	TO
cord-022561-rv5j1201	2414	4	20	20	CD
cord-022561-rv5j1201	2414	5	%	%	NN
cord-022561-rv5j1201	2414	6	of	of	IN
cord-022561-rv5j1201	2414	7	these	these	DT
cord-022561-rv5j1201	2414	8	cases	case	NNS
cord-022561-rv5j1201	2414	9	,	,	,
cord-022561-rv5j1201	2414	10	ruptured	ruptured	JJ
cord-022561-rv5j1201	2414	11	abscess	abscess	NN
cord-022561-rv5j1201	2414	12	material	material	NN
cord-022561-rv5j1201	2414	13	may	may	MD
cord-022561-rv5j1201	2414	14	spread	spread	VB
cord-022561-rv5j1201	2414	15	via	via	IN
cord-022561-rv5j1201	2414	16	blood	blood	NN
cord-022561-rv5j1201	2414	17	or	or	CC
cord-022561-rv5j1201	2414	18	lymph	lymph	NN
cord-022561-rv5j1201	2414	19	to	to	IN
cord-022561-rv5j1201	2414	20	other	other	JJ
cord-022561-rv5j1201	2414	21	organs	organ	NNS
cord-022561-rv5j1201	2414	22	(	(	-LRB-
cord-022561-rv5j1201	2414	23	metastatic	metastatic	JJ
cord-022561-rv5j1201	2414	24	abscess	abscess	NN
cord-022561-rv5j1201	2414	25	formation	formation	NN
cord-022561-rv5j1201	2414	26	,	,	,
cord-022561-rv5j1201	2414	27	bastard	bastard	NN
cord-022561-rv5j1201	2414	28	strangles	strangle	VBZ
cord-022561-rv5j1201	2414	29	)	)	-RRB-
cord-022561-rv5j1201	2414	30	,	,	,
cord-022561-rv5j1201	2414	31	including	include	VBG
cord-022561-rv5j1201	2414	32	lung	lung	NN
cord-022561-rv5j1201	2414	33	,	,	,
cord-022561-rv5j1201	2414	34	liver	liver	NN
cord-022561-rv5j1201	2414	35	,	,	,
cord-022561-rv5j1201	2414	36	kidney	kidney	NN
cord-022561-rv5j1201	2414	37	,	,	,
cord-022561-rv5j1201	2414	38	synovia	synovia	NNP
cord-022561-rv5j1201	2414	39	,	,	,
cord-022561-rv5j1201	2414	40	mesenteric	mesenteric	JJ
cord-022561-rv5j1201	2414	41	and	and	CC
cord-022561-rv5j1201	2414	42	mediastinal	mediastinal	JJ
cord-022561-rv5j1201	2414	43	lymph	lymph	NN
cord-022561-rv5j1201	2414	44	nodes	node	NNS
cord-022561-rv5j1201	2414	45	,	,	,
cord-022561-rv5j1201	2414	46	spleen	spleen	NNS
cord-022561-rv5j1201	2414	47	,	,	,
cord-022561-rv5j1201	2414	48	and	and	CC
cord-022561-rv5j1201	2414	49	occasionally	occasionally	RB
cord-022561-rv5j1201	2414	50	brain	brain	NN
cord-022561-rv5j1201	2414	51	.	.	.
cord-022561-rv5j1201	2415	1	Purpura	Purpura	NNP
cord-022561-rv5j1201	2415	2	hemorrhagica	hemorrhagica	NNP
cord-022561-rv5j1201	2415	3	,	,	,
cord-022561-rv5j1201	2415	4	a	a	DT
cord-022561-rv5j1201	2415	5	type	type	NN
cord-022561-rv5j1201	2415	6	III	iii	CD
cord-022561-rv5j1201	2415	7	hypersensitivity	hypersensitivity	NN
cord-022561-rv5j1201	2415	8	reaction	reaction	NN
cord-022561-rv5j1201	2415	9	,	,	,
cord-022561-rv5j1201	2415	10	may	may	MD
cord-022561-rv5j1201	2415	11	result	result	VB
cord-022561-rv5j1201	2415	12	in	in	IN
cord-022561-rv5j1201	2415	13	necrotizing	necrotize	VBG
cord-022561-rv5j1201	2415	14	vasculitis	vasculitis	NN
cord-022561-rv5j1201	2415	15	in	in	IN
cord-022561-rv5j1201	2415	16	some	some	DT
cord-022561-rv5j1201	2415	17	horses	horse	NNS
cord-022561-rv5j1201	2415	18	with	with	IN
cord-022561-rv5j1201	2415	19	repeated	repeat	VBN
cord-022561-rv5j1201	2415	20	natural	natural	JJ
cord-022561-rv5j1201	2415	21	exposure	exposure	NN
cord-022561-rv5j1201	2415	22	to	to	IN
cord-022561-rv5j1201	2415	23	S.	S.	NNP
cord-022561-rv5j1201	2415	24	equi	equi	NN
cord-022561-rv5j1201	2415	25	ssp	ssp	NN
cord-022561-rv5j1201	2415	26	.	.	.
cord-022561-rv5j1201	2416	1	equi	equi	NN
cord-022561-rv5j1201	2416	2	or	or	CC
cord-022561-rv5j1201	2416	3	after	after	IN
cord-022561-rv5j1201	2416	4	vaccination	vaccination	NN
cord-022561-rv5j1201	2416	5	in	in	IN
cord-022561-rv5j1201	2416	6	horses	horse	NNS
cord-022561-rv5j1201	2416	7	that	that	WDT
cord-022561-rv5j1201	2416	8	have	have	VBP
cord-022561-rv5j1201	2416	9	had	have	VBN
cord-022561-rv5j1201	2416	10	strangles	strangle	NNS
cord-022561-rv5j1201	2416	11	.	.	.
cord-022561-rv5j1201	2417	1	The	the	DT
cord-022561-rv5j1201	2417	2	typical	typical	JJ
cord-022561-rv5j1201	2417	3	manifestation	manifestation	NN
cord-022561-rv5j1201	2417	4	of	of	IN
cord-022561-rv5j1201	2417	5	R.	R.	NNP
cord-022561-rv5j1201	2417	6	equi	equi	NN
cord-022561-rv5j1201	2417	7	infection	infection	NN
cord-022561-rv5j1201	2417	8	is	be	VBZ
cord-022561-rv5j1201	2417	9	chronic	chronic	JJ
cord-022561-rv5j1201	2417	10	suppurative	suppurative	JJ
cord-022561-rv5j1201	2417	11	bronchopneumonia	bronchopneumonia	NN
cord-022561-rv5j1201	2417	12	with	with	IN
cord-022561-rv5j1201	2417	13	abscesses	abscess	NNS
cord-022561-rv5j1201	2417	14	(	(	-LRB-
cord-022561-rv5j1201	2417	15	see	see	VB
cord-022561-rv5j1201	2417	16	Chapter	chapter	NN
cord-022561-rv5j1201	2417	17	9	9	CD
cord-022561-rv5j1201	2417	18	)	)	-RRB-
cord-022561-rv5j1201	2417	19	.	.	.
cord-022561-rv5j1201	2418	1	Approximately	approximately	RB
cord-022561-rv5j1201	2418	2	50	50	CD
cord-022561-rv5j1201	2418	3	%	%	NN
cord-022561-rv5j1201	2418	4	of	of	IN
cord-022561-rv5j1201	2418	5	foals	foal	NNS
cord-022561-rv5j1201	2418	6	also	also	RB
cord-022561-rv5j1201	2418	7	develop	develop	VBP
cord-022561-rv5j1201	2418	8	intestinal	intestinal	JJ
cord-022561-rv5j1201	2418	9	lesions	lesion	NNS
cord-022561-rv5j1201	2418	10	characterized	characterize	VBN
cord-022561-rv5j1201	2418	11	by	by	IN
cord-022561-rv5j1201	2418	12	pyogranulomatous	pyogranulomatous	JJ
cord-022561-rv5j1201	2418	13	ulcerative	ulcerative	NNP
cord-022561-rv5j1201	2418	14	enterotyphlocolitis	enterotyphlocolitis	NNP
cord-022561-rv5j1201	2418	15	,	,	,
cord-022561-rv5j1201	2418	16	often	often	RB
cord-022561-rv5j1201	2418	17	over	over	IN
cord-022561-rv5j1201	2418	18	Peyer	Peyer	NNP
cord-022561-rv5j1201	2418	19	's	's	POS
cord-022561-rv5j1201	2418	20	patches	patch	NNS
cord-022561-rv5j1201	2418	21	,	,	,
cord-022561-rv5j1201	2418	22	and	and	CC
cord-022561-rv5j1201	2418	23	pyogranulomatous	pyogranulomatous	JJ
cord-022561-rv5j1201	2418	24	lymphadenitis	lymphadenitis	NNP
cord-022561-rv5j1201	2418	25	of	of	IN
cord-022561-rv5j1201	2418	26	mesenteric	mesenteric	JJ
cord-022561-rv5j1201	2418	27	and	and	CC
cord-022561-rv5j1201	2418	28	colonic	colonic	JJ
cord-022561-rv5j1201	2418	29	lymph	lymph	NN
cord-022561-rv5j1201	2418	30	nodes	node	NNS
cord-022561-rv5j1201	2418	31	(	(	-LRB-
cord-022561-rv5j1201	2418	32	see	see	VB
cord-022561-rv5j1201	2418	33	Chapter	chapter	NN
cord-022561-rv5j1201	2418	34	7	7	CD
cord-022561-rv5j1201	2418	35	;	;	:
cord-022561-rv5j1201	2418	36	see	see	VB
cord-022561-rv5j1201	2418	37	Fig	Fig	NNP
cord-022561-rv5j1201	2418	38	.	.	.
cord-022561-rv5j1201	2419	1	13	13	CD
cord-022561-rv5j1201	2419	2	-	-	SYM
cord-022561-rv5j1201	2419	3	68	68	CD
cord-022561-rv5j1201	2419	4	)	)	-RRB-
cord-022561-rv5j1201	2419	5	.	.	.
cord-022561-rv5j1201	2420	1	Large	large	JJ
cord-022561-rv5j1201	2420	2	abdominal	abdominal	JJ
cord-022561-rv5j1201	2420	3	abscesses	abscess	NNS
cord-022561-rv5j1201	2420	4	may	may	MD
cord-022561-rv5j1201	2420	5	be	be	VB
cord-022561-rv5j1201	2420	6	the	the	DT
cord-022561-rv5j1201	2420	7	only	only	JJ
cord-022561-rv5j1201	2420	8	lesion	lesion	NN
cord-022561-rv5j1201	2420	9	in	in	IN
cord-022561-rv5j1201	2420	10	the	the	DT
cord-022561-rv5j1201	2420	11	abdomen	abdomen	NN
cord-022561-rv5j1201	2420	12	and	and	CC
cord-022561-rv5j1201	2420	13	presumably	presumably	RB
cord-022561-rv5j1201	2420	14	originate	originate	VBP
cord-022561-rv5j1201	2420	15	from	from	IN
cord-022561-rv5j1201	2420	16	an	an	DT
cord-022561-rv5j1201	2420	17	infected	infected	JJ
cord-022561-rv5j1201	2420	18	mesenteric	mesenteric	JJ
cord-022561-rv5j1201	2420	19	lymph	lymph	NN
cord-022561-rv5j1201	2420	20	node	node	NN
cord-022561-rv5j1201	2420	21	.	.	.
cord-022561-rv5j1201	2421	1	The	the	DT
cord-022561-rv5j1201	2421	2	diffuse	diffuse	JJ
cord-022561-rv5j1201	2421	3	lymphatic	lymphatic	JJ
cord-022561-rv5j1201	2421	4	tissue	tissue	NN
cord-022561-rv5j1201	2421	5	in	in	IN
cord-022561-rv5j1201	2421	6	the	the	DT
cord-022561-rv5j1201	2421	7	lamina	lamina	JJ
cord-022561-rv5j1201	2421	8	propria	propria	NN
cord-022561-rv5j1201	2421	9	may	may	MD
cord-022561-rv5j1201	2421	10	contain	contain	VB
cord-022561-rv5j1201	2421	11	granulomatous	granulomatous	JJ
cord-022561-rv5j1201	2421	12	inflammation	inflammation	NN
cord-022561-rv5j1201	2421	13	with	with	IN
cord-022561-rv5j1201	2421	14	the	the	DT
cord-022561-rv5j1201	2421	15	phagocytized	phagocytized	JJ
cord-022561-rv5j1201	2421	16	bacteria	bacteria	NNS
cord-022561-rv5j1201	2421	17	.	.	.
cord-022561-rv5j1201	2422	1	Mediastinal	Mediastinal	NNP
cord-022561-rv5j1201	2422	2	pyogranulomatous	pyogranulomatous	JJ
cord-022561-rv5j1201	2422	3	lymphadenitis	lymphadenitis	NNP
cord-022561-rv5j1201	2422	4	may	may	MD
cord-022561-rv5j1201	2422	5	compress	compress	VB
cord-022561-rv5j1201	2422	6	the	the	DT
cord-022561-rv5j1201	2422	7	trachea	trachea	NN
cord-022561-rv5j1201	2422	8	,	,	,
cord-022561-rv5j1201	2422	9	causing	cause	VBG
cord-022561-rv5j1201	2422	10	respiratory	respiratory	JJ
cord-022561-rv5j1201	2422	11	distress	distress	NN
cord-022561-rv5j1201	2422	12	.	.	.
cord-022561-rv5j1201	2423	1	R.	R.	NNP
cord-022561-rv5j1201	2423	2	equi	equi	NN
cord-022561-rv5j1201	2423	3	lesions	lesion	NNS
cord-022561-rv5j1201	2423	4	also	also	RB
cord-022561-rv5j1201	2423	5	can	can	MD
cord-022561-rv5j1201	2423	6	develop	develop	VB
cord-022561-rv5j1201	2423	7	in	in	IN
cord-022561-rv5j1201	2423	8	the	the	DT
cord-022561-rv5j1201	2423	9	liver	liver	NN
cord-022561-rv5j1201	2423	10	,	,	,
cord-022561-rv5j1201	2423	11	kidney	kidney	NN
cord-022561-rv5j1201	2423	12	,	,	,
cord-022561-rv5j1201	2423	13	spleen	spleen	NNS
cord-022561-rv5j1201	2423	14	,	,	,
cord-022561-rv5j1201	2423	15	or	or	CC
cord-022561-rv5j1201	2423	16	nervous	nervous	JJ
cord-022561-rv5j1201	2423	17	tissue	tissue	NN
cord-022561-rv5j1201	2423	18	.	.	.
cord-022561-rv5j1201	2424	1	Lymphoma	Lymphoma	NNP
cord-022561-rv5j1201	2424	2	is	be	VBZ
cord-022561-rv5j1201	2424	3	the	the	DT
cord-022561-rv5j1201	2424	4	most	most	RBS
cord-022561-rv5j1201	2424	5	common	common	JJ
cord-022561-rv5j1201	2424	6	malignant	malignant	JJ
cord-022561-rv5j1201	2424	7	neoplasm	neoplasm	NN
cord-022561-rv5j1201	2424	8	in	in	IN
cord-022561-rv5j1201	2424	9	horses	horse	NNS
cord-022561-rv5j1201	2424	10	and	and	CC
cord-022561-rv5j1201	2424	11	mostly	mostly	RB
cord-022561-rv5j1201	2424	12	affects	affect	VBZ
cord-022561-rv5j1201	2424	13	adult	adult	NN
cord-022561-rv5j1201	2424	14	animals	animal	NNS
cord-022561-rv5j1201	2424	15	(	(	-LRB-
cord-022561-rv5j1201	2424	16	mean	mean	VB
cord-022561-rv5j1201	2424	17	age	age	NN
cord-022561-rv5j1201	2424	18	10	10	CD
cord-022561-rv5j1201	2424	19	to	to	TO
cord-022561-rv5j1201	2424	20	11	11	CD
cord-022561-rv5j1201	2424	21	years	year	NNS
cord-022561-rv5j1201	2424	22	)	)	-RRB-
cord-022561-rv5j1201	2424	23	with	with	IN
cord-022561-rv5j1201	2424	24	no	no	DT
cord-022561-rv5j1201	2424	25	lesions	lesion	NNS
cord-022561-rv5j1201	2424	26	that	that	WDT
cord-022561-rv5j1201	2424	27	involve	involve	VBP
cord-022561-rv5j1201	2424	28	distant	distant	JJ
cord-022561-rv5j1201	2424	29	sites	site	NNS
cord-022561-rv5j1201	2424	30	and	and	CC
cord-022561-rv5j1201	2424	31	has	have	VBZ
cord-022561-rv5j1201	2424	32	replaced	replace	VBN
cord-022561-rv5j1201	2424	33	the	the	DT
cord-022561-rv5j1201	2424	34	term	term	NN
cord-022561-rv5j1201	2424	35	malignant	malignant	JJ
cord-022561-rv5j1201	2424	36	histiocytosis	histiocytosis	NN
cord-022561-rv5j1201	2424	37	.	.	.
cord-022561-rv5j1201	2425	1	Breed	breed	JJ
cord-022561-rv5j1201	2425	2	predispositions	predisposition	NNS
cord-022561-rv5j1201	2425	3	to	to	IN
cord-022561-rv5j1201	2425	4	histiocytic	histiocytic	JJ
cord-022561-rv5j1201	2425	5	sarcoma	sarcoma	NN
cord-022561-rv5j1201	2425	6	complex	complex	NN
cord-022561-rv5j1201	2425	7	are	be	VBP
cord-022561-rv5j1201	2425	8	seen	see	VBN
cord-022561-rv5j1201	2425	9	in	in	IN
cord-022561-rv5j1201	2425	10	Bernese	bernese	JJ
cord-022561-rv5j1201	2425	11	mountain	mountain	NN
cord-022561-rv5j1201	2425	12	dogs	dog	NNS
cord-022561-rv5j1201	2425	13	,	,	,
cord-022561-rv5j1201	2425	14	Rottweilers	Rottweilers	NNPS
cord-022561-rv5j1201	2425	15	,	,	,
cord-022561-rv5j1201	2425	16	golden	golden	JJ
cord-022561-rv5j1201	2425	17	retrievers	retriever	NNS
cord-022561-rv5j1201	2425	18	,	,	,
cord-022561-rv5j1201	2425	19	and	and	CC
cord-022561-rv5j1201	2425	20	flat	flat	RB
cord-022561-rv5j1201	2425	21	-	-	HYPH
cord-022561-rv5j1201	2425	22	coated	coated	JJ
cord-022561-rv5j1201	2425	23	retrievers	retriever	NNS
cord-022561-rv5j1201	2425	24	,	,	,
cord-022561-rv5j1201	2425	25	though	though	IN
cord-022561-rv5j1201	2425	26	the	the	DT
cord-022561-rv5j1201	2425	27	disease	disease	NN
cord-022561-rv5j1201	2425	28	can	can	MD
cord-022561-rv5j1201	2425	29	occur	occur	VB
cord-022561-rv5j1201	2425	30	in	in	IN
cord-022561-rv5j1201	2425	31	any	any	DT
cord-022561-rv5j1201	2425	32	breed	breed	NN
cord-022561-rv5j1201	2425	33	.	.	.
cord-022561-rv5j1201	2426	1	Histiocytic	histiocytic	JJ
cord-022561-rv5j1201	2426	2	sarcoma	sarcoma	NN
cord-022561-rv5j1201	2426	3	complex	complex	NN
cord-022561-rv5j1201	2426	4	is	be	VBZ
cord-022561-rv5j1201	2426	5	considered	consider	VBN
cord-022561-rv5j1201	2426	6	to	to	TO
cord-022561-rv5j1201	2426	7	have	have	VB
cord-022561-rv5j1201	2426	8	a	a	DT
cord-022561-rv5j1201	2426	9	rapid	rapid	JJ
cord-022561-rv5j1201	2426	10	and	and	CC
cord-022561-rv5j1201	2426	11	highly	highly	RB
cord-022561-rv5j1201	2426	12	aggressive	aggressive	JJ
cord-022561-rv5j1201	2426	13	course	course	NN
cord-022561-rv5j1201	2426	14	,	,	,
cord-022561-rv5j1201	2426	15	and	and	CC
cord-022561-rv5j1201	2426	16	the	the	DT
cord-022561-rv5j1201	2426	17	clinical	clinical	JJ
cord-022561-rv5j1201	2426	18	signs	sign	NNS
cord-022561-rv5j1201	2426	19	depend	depend	VBP
cord-022561-rv5j1201	2426	20	on	on	IN
cord-022561-rv5j1201	2426	21	the	the	DT
cord-022561-rv5j1201	2426	22	particular	particular	JJ
cord-022561-rv5j1201	2426	23	organ(s	organ(s	NN
cord-022561-rv5j1201	2426	24	)	)	-RRB-
cord-022561-rv5j1201	2426	25	involved	involve	VBN
cord-022561-rv5j1201	2426	26	.	.	.
cord-022561-rv5j1201	2427	1	Grossly	grossly	RB
cord-022561-rv5j1201	2427	2	,	,	,
cord-022561-rv5j1201	2427	3	affected	affected	JJ
cord-022561-rv5j1201	2427	4	organs	organ	NNS
cord-022561-rv5j1201	2427	5	may	may	MD
cord-022561-rv5j1201	2427	6	be	be	VB
cord-022561-rv5j1201	2427	7	uniformly	uniformly	RB
cord-022561-rv5j1201	2427	8	enlarged	enlarge	VBN
cord-022561-rv5j1201	2427	9	and/or	and/or	CC
cord-022561-rv5j1201	2427	10	contain	contain	VB
cord-022561-rv5j1201	2427	11	multiple	multiple	JJ
cord-022561-rv5j1201	2427	12	coalescing	coalesce	VBG
cord-022561-rv5j1201	2427	13	white	white	JJ
cord-022561-rv5j1201	2427	14	-	-	HYPH
cord-022561-rv5j1201	2427	15	tan	tan	JJ
cord-022561-rv5j1201	2427	16	nodules	nodule	NNS
cord-022561-rv5j1201	2427	17	.	.	.
cord-022561-rv5j1201	2428	1	Tissue	tissue	NN
cord-022561-rv5j1201	2428	2	architecture	architecture	NN
cord-022561-rv5j1201	2428	3	is	be	VBZ
cord-022561-rv5j1201	2428	4	effaced	efface	VBN
cord-022561-rv5j1201	2428	5	by	by	IN
cord-022561-rv5j1201	2428	6	sheets	sheet	NNS
cord-022561-rv5j1201	2428	7	of	of	IN
cord-022561-rv5j1201	2428	8	pleomorphic	pleomorphic	JJ
cord-022561-rv5j1201	2428	9	round	round	NN
cord-022561-rv5j1201	2428	10	to	to	IN
cord-022561-rv5j1201	2428	11	spindle	spindle	NN
cord-022561-rv5j1201	2428	12	-	-	HYPH
cord-022561-rv5j1201	2428	13	shaped	shape	VBN
cord-022561-rv5j1201	2428	14	cells	cell	NNS
cord-022561-rv5j1201	2428	15	.	.	.
cord-022561-rv5j1201	2429	1	There	there	EX
cord-022561-rv5j1201	2429	2	is	be	VBZ
cord-022561-rv5j1201	2429	3	marked	mark	VBN
cord-022561-rv5j1201	2429	4	cellular	cellular	JJ
cord-022561-rv5j1201	2429	5	atypia	atypia	NN
cord-022561-rv5j1201	2429	6	with	with	IN
cord-022561-rv5j1201	2429	7	numerous	numerous	JJ
cord-022561-rv5j1201	2429	8	karyomegalic	karyomegalic	NN
cord-022561-rv5j1201	2429	9	and	and	CC
cord-022561-rv5j1201	2429	10	multinucleated	multinucleated	JJ
cord-022561-rv5j1201	2429	11	neoplastic	neoplastic	JJ
cord-022561-rv5j1201	2429	12	cells	cell	NNS
cord-022561-rv5j1201	2430	1	(	(	-LRB-
cord-022561-rv5j1201	2430	2	Fig	Fig	NNP
cord-022561-rv5j1201	2430	3	.	.	.
cord-022561-rv5j1201	2430	4	13	13	CD
cord-022561-rv5j1201	2430	5	-	-	SYM
cord-022561-rv5j1201	2430	6	85	85	CD
cord-022561-rv5j1201	2430	7	)	)	-RRB-
cord-022561-rv5j1201	2430	8	.	.	.
cord-022561-rv5j1201	2431	1	Hemophagocytic	hemophagocytic	JJ
cord-022561-rv5j1201	2431	2	Histiocytic	Histiocytic	NNP
cord-022561-rv5j1201	2431	3	Sarcoma	Sarcoma	NNP
cord-022561-rv5j1201	2431	4	.	.	.
cord-022561-rv5j1201	2432	1	Hemophagocytic	hemophagocytic	JJ
cord-022561-rv5j1201	2432	2	histiocytic	histiocytic	JJ
cord-022561-rv5j1201	2432	3	sarcoma	sarcoma	NN
cord-022561-rv5j1201	2432	4	is	be	VBZ
cord-022561-rv5j1201	2432	5	seen	see	VBN
cord-022561-rv5j1201	2432	6	in	in	IN
cord-022561-rv5j1201	2432	7	dogs	dog	NNS
cord-022561-rv5j1201	2432	8	and	and	CC
cord-022561-rv5j1201	2432	9	cats	cat	NNS
cord-022561-rv5j1201	2432	10	and	and	CC
cord-022561-rv5j1201	2432	11	is	be	VBZ
cord-022561-rv5j1201	2432	12	a	a	DT
cord-022561-rv5j1201	2432	13	neoplasm	neoplasm	NN
cord-022561-rv5j1201	2432	14	of	of	IN
cord-022561-rv5j1201	2432	15	macrophages	macrophage	NNS
cord-022561-rv5j1201	2432	16	of	of	IN
cord-022561-rv5j1201	2432	17	the	the	DT
cord-022561-rv5j1201	2432	18	spleen	spleen	NN
cord-022561-rv5j1201	2432	19	and	and	CC
cord-022561-rv5j1201	2432	20	bone	bone	NN
cord-022561-rv5j1201	2432	21	marrow	marrow	NN
cord-022561-rv5j1201	2432	22	.	.	.
cord-022561-rv5j1201	2433	1	Clinically	clinically	RB
cord-022561-rv5j1201	2433	2	,	,	,
cord-022561-rv5j1201	2433	3	dogs	dog	NNS
cord-022561-rv5j1201	2433	4	present	present	JJ
cord-022561-rv5j1201	2433	5	with	with	IN
cord-022561-rv5j1201	2433	6	hemolytic	hemolytic	JJ
cord-022561-rv5j1201	2433	7	regenerative	regenerative	JJ
cord-022561-rv5j1201	2433	8	anemia	anemia	NN
cord-022561-rv5j1201	2433	9	and	and	CC
cord-022561-rv5j1201	2433	10	thrombocytopenia	thrombocytopenia	NN
cord-022561-rv5j1201	2433	11	,	,	,
cord-022561-rv5j1201	2433	12	thus	thus	RB
cord-022561-rv5j1201	2433	13	mimicking	mimic	VBG
cord-022561-rv5j1201	2433	14	Evans	Evans	NNP
cord-022561-rv5j1201	2433	15	's	's	POS
cord-022561-rv5j1201	2433	16	syndrome	syndrome	NN
cord-022561-rv5j1201	2433	17	,	,	,
cord-022561-rv5j1201	2433	18	though	though	IN
cord-022561-rv5j1201	2433	19	they	-PRON-	PRP
cord-022561-rv5j1201	2433	20	are	be	VBP
cord-022561-rv5j1201	2433	21	Coombs	Coombs	NNP
cord-022561-rv5j1201	2433	22	negative	negative	JJ
cord-022561-rv5j1201	2433	23	.	.	.
cord-022561-rv5j1201	2434	1	This	this	DT
cord-022561-rv5j1201	2434	2	form	form	NN
cord-022561-rv5j1201	2434	3	of	of	IN
cord-022561-rv5j1201	2434	4	histiocytic	histiocytic	JJ
cord-022561-rv5j1201	2434	5	sarcoma	sarcoma	NN
cord-022561-rv5j1201	2434	6	carries	carry	VBZ
cord-022561-rv5j1201	2434	7	the	the	DT
cord-022561-rv5j1201	2434	8	worst	bad	JJS
cord-022561-rv5j1201	2434	9	prognosis	prognosis	NN
cord-022561-rv5j1201	2434	10	of	of	IN
cord-022561-rv5j1201	2434	11	the	the	DT
cord-022561-rv5j1201	2434	12	histiocytic	histiocytic	JJ
cord-022561-rv5j1201	2434	13	sarcomas	sarcoma	NNS
cord-022561-rv5j1201	2434	14	,	,	,
cord-022561-rv5j1201	2434	15	which	which	WDT
cord-022561-rv5j1201	2434	16	is	be	VBZ
cord-022561-rv5j1201	2434	17	likely	likely	JJ
cord-022561-rv5j1201	2434	18	in	in	IN
cord-022561-rv5j1201	2434	19	part	part	NN
cord-022561-rv5j1201	2434	20	related	relate	VBN
cord-022561-rv5j1201	2434	21	to	to	IN
cord-022561-rv5j1201	2434	22	the	the	DT
cord-022561-rv5j1201	2434	23	severe	severe	JJ
cord-022561-rv5j1201	2434	24	anemia	anemia	NN
cord-022561-rv5j1201	2434	25	and	and	CC
cord-022561-rv5j1201	2434	26	coagulopathy	coagulopathy	NN
cord-022561-rv5j1201	2434	27	.	.	.
cord-022561-rv5j1201	2435	1	It	-PRON-	PRP
cord-022561-rv5j1201	2435	2	is	be	VBZ
cord-022561-rv5j1201	2435	3	characterized	characterize	VBN
cord-022561-rv5j1201	2435	4	by	by	IN
cord-022561-rv5j1201	2435	5	a	a	DT
cord-022561-rv5j1201	2435	6	non	non	JJ
cord-022561-rv5j1201	2435	7	-	-	JJ
cord-022561-rv5j1201	2435	8	mass	mass	JJ
cord-022561-rv5j1201	2435	9	forming	form	VBG
cord-022561-rv5j1201	2435	10	infiltrate	infiltrate	NN
cord-022561-rv5j1201	2435	11	of	of	IN
cord-022561-rv5j1201	2435	12	histiocytes	histiocyte	NNS
cord-022561-rv5j1201	2435	13	within	within	IN
cord-022561-rv5j1201	2435	14	the	the	DT
cord-022561-rv5j1201	2435	15	bone	bone	NN
cord-022561-rv5j1201	2435	16	marrow	marrow	NN
cord-022561-rv5j1201	2435	17	and	and	CC
cord-022561-rv5j1201	2435	18	splenic	splenic	JJ
cord-022561-rv5j1201	2435	19	red	red	JJ
cord-022561-rv5j1201	2435	20	pulp	pulp	NN
cord-022561-rv5j1201	2435	21	,	,	,
cord-022561-rv5j1201	2435	22	causing	cause	VBG
cord-022561-rv5j1201	2435	23	diffuse	diffuse	JJ
cord-022561-rv5j1201	2435	24	splenomegaly	splenomegaly	NN
cord-022561-rv5j1201	2435	25	.	.	.
cord-022561-rv5j1201	2436	1	The	the	DT
cord-022561-rv5j1201	2436	2	neoplastic	neoplastic	JJ
cord-022561-rv5j1201	2436	3	cells	cell	NNS
cord-022561-rv5j1201	2436	4	exhibit	exhibit	VBP
cord-022561-rv5j1201	2436	5	marked	mark	VBN
cord-022561-rv5j1201	2436	6	erythrophagocytosis	erythrophagocytosis	NN
cord-022561-rv5j1201	2436	7	,	,	,
cord-022561-rv5j1201	2436	8	but	but	CC
cord-022561-rv5j1201	2436	9	the	the	DT
cord-022561-rv5j1201	2436	10	severe	severe	JJ
cord-022561-rv5j1201	2436	11	cellular	cellular	JJ
cord-022561-rv5j1201	2436	12	pleomorphism	pleomorphism	NN
cord-022561-rv5j1201	2436	13	seen	see	VBN
cord-022561-rv5j1201	2436	14	in	in	IN
cord-022561-rv5j1201	2436	15	the	the	DT
cord-022561-rv5j1201	2436	16	histiocytic	histiocytic	JJ
cord-022561-rv5j1201	2436	17	sarcoma	sarcoma	NN
cord-022561-rv5j1201	2436	18	complex	complex	NN
cord-022561-rv5j1201	2436	19	may	may	MD
cord-022561-rv5j1201	2436	20	be	be	VB
cord-022561-rv5j1201	2436	21	lacking	lack	VBG
cord-022561-rv5j1201	2436	22	.	.	.
cord-022561-rv5j1201	2437	1	The	the	DT
cord-022561-rv5j1201	2437	2	neoplastic	neoplastic	JJ
cord-022561-rv5j1201	2437	3	cells	cell	NNS
cord-022561-rv5j1201	2437	4	are	be	VBP
cord-022561-rv5j1201	2437	5	often	often	RB
cord-022561-rv5j1201	2437	6	intermixed	intermix	VBN
cord-022561-rv5j1201	2437	7	with	with	IN
cord-022561-rv5j1201	2437	8	EMH	EMH	NNP
cord-022561-rv5j1201	2437	9	and	and	CC
cord-022561-rv5j1201	2437	10	plasma	plasma	NN
cord-022561-rv5j1201	2437	11	cells	cell	NNS
cord-022561-rv5j1201	2437	12	.	.	.
cord-022561-rv5j1201	2438	1	Metastasis	metastasis	NN
cord-022561-rv5j1201	2438	2	is	be	VBZ
cord-022561-rv5j1201	2438	3	frequently	frequently	RB
cord-022561-rv5j1201	2438	4	to	to	IN
cord-022561-rv5j1201	2438	5	the	the	DT
cord-022561-rv5j1201	2438	6	liver	liver	NN
cord-022561-rv5j1201	2438	7	,	,	,
cord-022561-rv5j1201	2438	8	where	where	WRB
cord-022561-rv5j1201	2438	9	the	the	DT
cord-022561-rv5j1201	2438	10	cells	cell	NNS
cord-022561-rv5j1201	2438	11	concentrate	concentrate	VBP
cord-022561-rv5j1201	2438	12	within	within	IN
cord-022561-rv5j1201	2438	13	the	the	DT
cord-022561-rv5j1201	2438	14	sinuses	sinus	NNS
cord-022561-rv5j1201	2438	15	.	.	.
cord-022561-rv5j1201	2439	1	Tumor	tumor	NN
cord-022561-rv5j1201	2439	2	emboli	embolus	NNS
cord-022561-rv5j1201	2439	3	within	within	IN
cord-022561-rv5j1201	2439	4	the	the	DT
cord-022561-rv5j1201	2439	5	lung	lung	NN
cord-022561-rv5j1201	2439	6	are	be	VBP
cord-022561-rv5j1201	2439	7	often	often	RB
cord-022561-rv5j1201	2439	8	present	present	JJ
cord-022561-rv5j1201	2439	9	.	.	.
cord-022561-rv5j1201	2440	1	MALT	malt	NN
cord-022561-rv5j1201	2440	2	is	be	VBZ
cord-022561-rv5j1201	2440	3	involved	involve	VBN
cord-022561-rv5j1201	2440	4	in	in	IN
cord-022561-rv5j1201	2440	5	a	a	DT
cord-022561-rv5j1201	2440	6	variety	variety	NN
cord-022561-rv5j1201	2440	7	of	of	IN
cord-022561-rv5j1201	2440	8	ways	way	NNS
cord-022561-rv5j1201	2440	9	with	with	IN
cord-022561-rv5j1201	2440	10	bacteria	bacteria	NNS
cord-022561-rv5j1201	2440	11	and	and	CC
cord-022561-rv5j1201	2440	12	viruses	virus	NNS
cord-022561-rv5j1201	2440	13	,	,	,
cord-022561-rv5j1201	2440	14	and	and	CC
cord-022561-rv5j1201	2440	15	these	these	DT
cord-022561-rv5j1201	2440	16	are	be	VBP
cord-022561-rv5j1201	2440	17	summarized	summarize	VBN
cord-022561-rv5j1201	2440	18	for	for	IN
cord-022561-rv5j1201	2440	19	large	large	JJ
cord-022561-rv5j1201	2440	20	animals	animal	NNS
cord-022561-rv5j1201	2440	21	in	in	IN
cord-022561-rv5j1201	2440	22	Table	Table	NNP
cord-022561-rv5j1201	2440	23	13	13	CD
cord-022561-rv5j1201	2440	24	-5	-5	CD
cord-022561-rv5j1201	2440	25	.	.	.
cord-022561-rv5j1201	2441	1	These	these	DT
cord-022561-rv5j1201	2441	2	interactions	interaction	NNS
cord-022561-rv5j1201	2441	3	include	include	VBP
cord-022561-rv5j1201	2441	4	being	be	VBG
cord-022561-rv5j1201	2441	5	a	a	DT
cord-022561-rv5j1201	2441	6	portal	portal	NN
cord-022561-rv5j1201	2441	7	of	of	IN
cord-022561-rv5j1201	2441	8	entry	entry	NN
cord-022561-rv5j1201	2441	9	for	for	IN
cord-022561-rv5j1201	2441	10	pathogens	pathogen	NNS
cord-022561-rv5j1201	2441	11	(	(	-LRB-
cord-022561-rv5j1201	2441	12	e.g.	e.g.	RB
cord-022561-rv5j1201	2441	13	,	,	,
cord-022561-rv5j1201	2441	14	Salmonella	Salmonella	NNP
cord-022561-rv5j1201	2441	15	spp	spp	NNS
cord-022561-rv5j1201	2441	16	.	.	.
cord-022561-rv5j1201	2442	1	,	,	,
cord-022561-rv5j1201	2442	2	Yersinia	Yersinia	NNP
cord-022561-rv5j1201	2442	3	pestis	pestis	NN
cord-022561-rv5j1201	2442	4	,	,	,
cord-022561-rv5j1201	2442	5	MAP	MAP	NNP
cord-022561-rv5j1201	2442	6	,	,	,
cord-022561-rv5j1201	2442	7	and	and	CC
cord-022561-rv5j1201	2442	8	L.	L.	NNP
cord-022561-rv5j1201	2442	9	monocytogenes	monocytogenes	NNP
cord-022561-rv5j1201	2442	10	)	)	-RRB-
cord-022561-rv5j1201	2442	11	;	;	:
cord-022561-rv5j1201	2442	12	a	a	DT
cord-022561-rv5j1201	2442	13	site	site	NN
cord-022561-rv5j1201	2442	14	of	of	IN
cord-022561-rv5j1201	2442	15	replication	replication	NN
cord-022561-rv5j1201	2442	16	for	for	IN
cord-022561-rv5j1201	2442	17	viruses	virus	NNS
cord-022561-rv5j1201	2442	18	(	(	-LRB-
cord-022561-rv5j1201	2442	19	e.g.	e.g.	RB
cord-022561-rv5j1201	2442	20	,	,	,
cord-022561-rv5j1201	2442	21	BVDV	BVDV	NNP
cord-022561-rv5j1201	2442	22	)	)	-RRB-
cord-022561-rv5j1201	2442	23	;	;	:
cord-022561-rv5j1201	2442	24	a	a	DT
cord-022561-rv5j1201	2442	25	site	site	NN
cord-022561-rv5j1201	2442	26	for	for	IN
cord-022561-rv5j1201	2442	27	hematogenous	hematogenous	JJ
cord-022561-rv5j1201	2442	28	infection	infection	NN
cord-022561-rv5j1201	2442	29	(	(	-LRB-
cord-022561-rv5j1201	2442	30	e.g.	e.g.	RB
cord-022561-rv5j1201	2442	31	,	,	,
cord-022561-rv5j1201	2442	32	panleukopenia	panleukopenia	FW
cord-022561-rv5j1201	2442	33	virus	virus	NN
cord-022561-rv5j1201	2442	34	and	and	CC
cord-022561-rv5j1201	2442	35	parvovirus	parvovirus	NN
cord-022561-rv5j1201	2442	36	)	)	-RRB-
cord-022561-rv5j1201	2442	37	;	;	:
cord-022561-rv5j1201	2442	38	and	and	CC
cord-022561-rv5j1201	2442	39	a	a	DT
cord-022561-rv5j1201	2442	40	site	site	NN
cord-022561-rv5j1201	2442	41	of	of	IN
cord-022561-rv5j1201	2442	42	gross	gross	JJ
cord-022561-rv5j1201	2442	43	or	or	CC
cord-022561-rv5j1201	2442	44	microscopic	microscopic	JJ
cord-022561-rv5j1201	2442	45	lesions	lesion	NNS
cord-022561-rv5j1201	2442	46	in	in	IN
cord-022561-rv5j1201	2442	47	some	some	DT
cord-022561-rv5j1201	2442	48	viral	viral	JJ
cord-022561-rv5j1201	2442	49	diseases	disease	NNS
cord-022561-rv5j1201	2442	50	.	.	.
cord-022561-rv5j1201	2443	1	Bovine	bovine	JJ
cord-022561-rv5j1201	2443	2	coronavirus	coronavirus	NN
cord-022561-rv5j1201	2443	3	,	,	,
cord-022561-rv5j1201	2443	4	BVDV	BVDV	NNP
cord-022561-rv5j1201	2443	5	,	,	,
cord-022561-rv5j1201	2443	6	rinderpest	rinderpest	NN
cord-022561-rv5j1201	2443	7	virus	virus	NN
cord-022561-rv5j1201	2443	8	,	,	,
cord-022561-rv5j1201	2443	9	malignant	malignant	JJ
cord-022561-rv5j1201	2443	10	catarrhal	catarrhal	NN
cord-022561-rv5j1201	2443	11	fever	fever	NN
cord-022561-rv5j1201	2443	12	virus	virus	NN
cord-022561-rv5j1201	2443	13	,	,	,
cord-022561-rv5j1201	2443	14	feline	feline	JJ
cord-022561-rv5j1201	2443	15	panleukopenia	panleukopenia	NNP
cord-022561-rv5j1201	2443	16	virus	virus	NN
cord-022561-rv5j1201	2443	17	,	,	,
cord-022561-rv5j1201	2443	18	and	and	CC
cord-022561-rv5j1201	2443	19	canine	canine	JJ
cord-022561-rv5j1201	2443	20	parvovirus	parvovirus	NN
cord-022561-rv5j1201	2443	21	cause	cause	VBP
cord-022561-rv5j1201	2443	22	lymphocyte	lymphocyte	NN
cord-022561-rv5j1201	2443	23	depletion	depletion	NN
cord-022561-rv5j1201	2443	24	within	within	IN
cord-022561-rv5j1201	2443	25	the	the	DT
cord-022561-rv5j1201	2443	26	MALT	malt	NN
cord-022561-rv5j1201	2443	27	.	.	.
cord-022561-rv5j1201	2443	28	 	 	_SP
cord-022561-rv5j1201	2444	1	Anthrax	Anthrax	NNP
cord-022561-rv5j1201	2444	2	is	be	VBZ
cord-022561-rv5j1201	2444	3	caused	cause	VBN
cord-022561-rv5j1201	2444	4	by	by	IN
cord-022561-rv5j1201	2444	5	B.	B.	NNP
cord-022561-rv5j1201	2444	6	anthracis	anthracis	NNP
cord-022561-rv5j1201	2444	7	,	,	,
cord-022561-rv5j1201	2444	8	a	a	DT
cord-022561-rv5j1201	2444	9	Gram	gram	NN
cord-022561-rv5j1201	2444	10	-	-	HYPH
cord-022561-rv5j1201	2444	11	positive	positive	JJ
cord-022561-rv5j1201	2444	12	bacillus	bacillus	NN
cord-022561-rv5j1201	2444	13	found	find	VBN
cord-022561-rv5j1201	2444	14	in	in	IN
cord-022561-rv5j1201	2444	15	spore	spore	NN
cord-022561-rv5j1201	2444	16	form	form	NN
cord-022561-rv5j1201	2444	17	in	in	IN
cord-022561-rv5j1201	2444	18	soil	soil	NN
cord-022561-rv5j1201	2444	19	.	.	.
cord-022561-rv5j1201	2445	1	Cattle	Cattle	NNS
cord-022561-rv5j1201	2445	2	,	,	,
cord-022561-rv5j1201	2445	3	sheep	sheep	NNS
cord-022561-rv5j1201	2445	4	,	,	,
cord-022561-rv5j1201	2445	5	and	and	CC
cord-022561-rv5j1201	2445	6	goats	goat	NNS
cord-022561-rv5j1201	2445	7	become	become	VBP
cord-022561-rv5j1201	2445	8	infected	infected	JJ
cord-022561-rv5j1201	2445	9	when	when	WRB
cord-022561-rv5j1201	2445	10	grazing	graze	VBG
cord-022561-rv5j1201	2445	11	on	on	IN
cord-022561-rv5j1201	2445	12	infected	infected	JJ
cord-022561-rv5j1201	2445	13	soil	soil	NN
cord-022561-rv5j1201	2445	14	,	,	,
cord-022561-rv5j1201	2445	15	and	and	CC
cord-022561-rv5j1201	2445	16	infection	infection	NN
cord-022561-rv5j1201	2445	17	causes	cause	VBZ
cord-022561-rv5j1201	2445	18	fulminant	fulminant	JJ
cord-022561-rv5j1201	2445	19	septicemia	septicemia	NN
cord-022561-rv5j1201	2445	20	.	.	.
cord-022561-rv5j1201	2446	1	The	the	DT
cord-022561-rv5j1201	2446	2	spleen	spleen	NNS
cord-022561-rv5j1201	2446	3	in	in	IN
cord-022561-rv5j1201	2446	4	infected	infected	JJ
cord-022561-rv5j1201	2446	5	animals	animal	NNS
cord-022561-rv5j1201	2446	6	is	be	VBZ
cord-022561-rv5j1201	2446	7	markedly	markedly	RB
cord-022561-rv5j1201	2446	8	enlarged	enlarge	VBN
cord-022561-rv5j1201	2446	9	and	and	CC
cord-022561-rv5j1201	2446	10	congested	congested	JJ
cord-022561-rv5j1201	2446	11	(	(	-LRB-
cord-022561-rv5j1201	2446	12	see	see	VB
cord-022561-rv5j1201	2446	13	Uniform	Uniform	NNP
cord-022561-rv5j1201	2446	14	Splenomegaly	Splenomegaly	NNP
cord-022561-rv5j1201	2446	15	with	with	IN
cord-022561-rv5j1201	2446	16	a	a	DT
cord-022561-rv5j1201	2446	17	Bloody	Bloody	NNP
cord-022561-rv5j1201	2446	18	Consistency	Consistency	NNP
cord-022561-rv5j1201	2446	19	;	;	:
cord-022561-rv5j1201	2446	20	see	see	VB
cord-022561-rv5j1201	2446	21	also	also	RB
cord-022561-rv5j1201	2446	22	Chapter	chapter	NN
cord-022561-rv5j1201	2446	23	4	4	CD
cord-022561-rv5j1201	2446	24	)	)	-RRB-
cord-022561-rv5j1201	2446	25	.	.	.
cord-022561-rv5j1201	2447	1	Bovine	bovine	JJ
cord-022561-rv5j1201	2447	2	viral	viral	JJ
cord-022561-rv5j1201	2447	3	diarrhea	diarrhea	NN
cord-022561-rv5j1201	2447	4	is	be	VBZ
cord-022561-rv5j1201	2447	5	caused	cause	VBN
cord-022561-rv5j1201	2447	6	by	by	IN
cord-022561-rv5j1201	2447	7	BVDV	BVDV	NNP
cord-022561-rv5j1201	2447	8	,	,	,
cord-022561-rv5j1201	2447	9	a	a	DT
cord-022561-rv5j1201	2447	10	pestivirus	pestivirus	NN
cord-022561-rv5j1201	2447	11	.	.	.
cord-022561-rv5j1201	2448	1	Cattle	Cattle	NNS
cord-022561-rv5j1201	2448	2	are	be	VBP
cord-022561-rv5j1201	2448	3	the	the	DT
cord-022561-rv5j1201	2448	4	natural	natural	JJ
cord-022561-rv5j1201	2448	5	host	host	NN
cord-022561-rv5j1201	2448	6	,	,	,
cord-022561-rv5j1201	2448	7	but	but	CC
cord-022561-rv5j1201	2448	8	other	other	JJ
cord-022561-rv5j1201	2448	9	animals	animal	NNS
cord-022561-rv5j1201	2448	10	such	such	JJ
cord-022561-rv5j1201	2448	11	as	as	IN
cord-022561-rv5j1201	2448	12	alpacas	alpaca	NNS
cord-022561-rv5j1201	2448	13	,	,	,
cord-022561-rv5j1201	2448	14	deer	deer	NN
cord-022561-rv5j1201	2448	15	,	,	,
cord-022561-rv5j1201	2448	16	sheep	sheep	NN
cord-022561-rv5j1201	2448	17	,	,	,
cord-022561-rv5j1201	2448	18	and	and	CC
cord-022561-rv5j1201	2448	19	goats	goat	NNS
cord-022561-rv5j1201	2448	20	are	be	VBP
cord-022561-rv5j1201	2448	21	also	also	RB
cord-022561-rv5j1201	2448	22	affected	affect	VBN
cord-022561-rv5j1201	2448	23	.	.	.
cord-022561-rv5j1201	2449	1	BVDV	BVDV	NNP
cord-022561-rv5j1201	2449	2	preferentially	preferentially	RB
cord-022561-rv5j1201	2449	3	infects	infect	VBZ
cord-022561-rv5j1201	2449	4	cells	cell	NNS
cord-022561-rv5j1201	2449	5	of	of	IN
cord-022561-rv5j1201	2449	6	the	the	DT
cord-022561-rv5j1201	2449	7	immune	immune	JJ
cord-022561-rv5j1201	2449	8	system	system	NN
cord-022561-rv5j1201	2449	9	,	,	,
cord-022561-rv5j1201	2449	10	including	include	VBG
cord-022561-rv5j1201	2449	11	macrophages	macrophage	NNS
cord-022561-rv5j1201	2449	12	,	,	,
cord-022561-rv5j1201	2449	13	DCs	dc	NNS
cord-022561-rv5j1201	2449	14	,	,	,
cord-022561-rv5j1201	2449	15	and	and	CC
cord-022561-rv5j1201	2449	16	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	2449	17	.	.	.
cord-022561-rv5j1201	2450	1	The	the	DT
cord-022561-rv5j1201	2450	2	associated	associated	JJ
cord-022561-rv5j1201	2450	3	lesions	lesion	NNS
cord-022561-rv5j1201	2450	4	in	in	IN
cord-022561-rv5j1201	2450	5	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	2450	6	tissues	tissue	NNS
cord-022561-rv5j1201	2450	7	are	be	VBP
cord-022561-rv5j1201	2450	8	severe	severe	JJ
cord-022561-rv5j1201	2450	9	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	2450	10	depletion	depletion	NN
cord-022561-rv5j1201	2450	11	in	in	IN
cord-022561-rv5j1201	2450	12	mesenteric	mesenteric	JJ
cord-022561-rv5j1201	2450	13	lymph	lymph	NN
cord-022561-rv5j1201	2450	14	nodes	node	NNS
cord-022561-rv5j1201	2450	15	and	and	CC
cord-022561-rv5j1201	2450	16	Peyer	Peyer	NNP
cord-022561-rv5j1201	2450	17	's	's	POS
cord-022561-rv5j1201	2450	18	patches	patch	NNS
cord-022561-rv5j1201	2450	19	,	,	,
cord-022561-rv5j1201	2450	20	whose	whose	WP$
cord-022561-rv5j1201	2450	21	intestinal	intestinal	JJ
cord-022561-rv5j1201	2450	22	surface	surface	NN
cord-022561-rv5j1201	2450	23	may	may	MD
cord-022561-rv5j1201	2450	24	be	be	VB
cord-022561-rv5j1201	2450	25	covered	cover	VBN
cord-022561-rv5j1201	2450	26	by	by	IN
cord-022561-rv5j1201	2450	27	a	a	DT
cord-022561-rv5j1201	2450	28	fibrinonecrotic	fibrinonecrotic	JJ
cord-022561-rv5j1201	2450	29	membrane	membrane	NN
cord-022561-rv5j1201	2450	30	.	.	.
cord-022561-rv5j1201	2451	1	Histologically	histologically	RB
cord-022561-rv5j1201	2451	2	,	,	,
cord-022561-rv5j1201	2451	3	there	there	EX
cord-022561-rv5j1201	2451	4	is	be	VBZ
cord-022561-rv5j1201	2451	5	marked	mark	VBN
cord-022561-rv5j1201	2451	6	lymphocytolysis	lymphocytolysis	NN
cord-022561-rv5j1201	2451	7	and	and	CC
cord-022561-rv5j1201	2451	8	necrosis	necrosis	NN
cord-022561-rv5j1201	2451	9	of	of	IN
cord-022561-rv5j1201	2451	10	germinal	germinal	JJ
cord-022561-rv5j1201	2451	11	centers	center	NNS
cord-022561-rv5j1201	2451	12	in	in	IN
cord-022561-rv5j1201	2451	13	Peyer	Peyer	NNP
cord-022561-rv5j1201	2451	14	's	's	POS
cord-022561-rv5j1201	2451	15	patches	patch	NNS
cord-022561-rv5j1201	2451	16	and	and	CC
cord-022561-rv5j1201	2451	17	cortices	cortex	NNS
cord-022561-rv5j1201	2451	18	of	of	IN
cord-022561-rv5j1201	2451	19	lymph	lymph	NN
cord-022561-rv5j1201	2451	20	nodes	node	NNS
cord-022561-rv5j1201	2451	21	.	.	.
cord-022561-rv5j1201	2452	1	There	there	EX
cord-022561-rv5j1201	2452	2	is	be	VBZ
cord-022561-rv5j1201	2452	3	thymic	thymic	JJ
cord-022561-rv5j1201	2452	4	atrophy	atrophy	NN
cord-022561-rv5j1201	2452	5	because	because	IN
cord-022561-rv5j1201	2452	6	the	the	DT
cord-022561-rv5j1201	2452	7	thymus	thymus	NN
cord-022561-rv5j1201	2452	8	is	be	VBZ
cord-022561-rv5j1201	2452	9	markedly	markedly	RB
cord-022561-rv5j1201	2452	10	depleted	deplete	VBN
cord-022561-rv5j1201	2452	11	of	of	IN
cord-022561-rv5j1201	2452	12	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	2452	13	and	and	CC
cord-022561-rv5j1201	2452	14	may	may	MD
cord-022561-rv5j1201	2452	15	consist	consist	VB
cord-022561-rv5j1201	2452	16	of	of	IN
cord-022561-rv5j1201	2452	17	only	only	RB
cord-022561-rv5j1201	2452	18	collapsed	collapse	VBN
cord-022561-rv5j1201	2452	19	stroma	stroma	NN
cord-022561-rv5j1201	2452	20	and	and	CC
cord-022561-rv5j1201	2452	21	few	few	JJ
cord-022561-rv5j1201	2452	22	scattered	scatter	VBN
cord-022561-rv5j1201	2452	23	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	2452	24	.	.	.
cord-022561-rv5j1201	2453	1	BVD	BVD	NNP
cord-022561-rv5j1201	2453	2	is	be	VBZ
cord-022561-rv5j1201	2453	3	discussed	discuss	VBN
cord-022561-rv5j1201	2453	4	in	in	IN
cord-022561-rv5j1201	2453	5	detail	detail	NN
cord-022561-rv5j1201	2453	6	in	in	IN
cord-022561-rv5j1201	2453	7	Chapters	chapter	NNS
cord-022561-rv5j1201	2453	8	4	4	CD
cord-022561-rv5j1201	2453	9	and	and	CC
cord-022561-rv5j1201	2453	10	7	7	CD
cord-022561-rv5j1201	2453	11	.	.	.
cord-022561-rv5j1201	2454	1	apparent	apparent	JJ
cord-022561-rv5j1201	2454	2	breed	breed	NN
cord-022561-rv5j1201	2454	3	or	or	CC
cord-022561-rv5j1201	2454	4	sex	sex	NN
cord-022561-rv5j1201	2454	5	predisposition	predisposition	NN
cord-022561-rv5j1201	2454	6	.	.	.
cord-022561-rv5j1201	2455	1	The	the	DT
cord-022561-rv5j1201	2455	2	most	most	RBS
cord-022561-rv5j1201	2455	3	frequent	frequent	JJ
cord-022561-rv5j1201	2455	4	anatomic	anatomic	JJ
cord-022561-rv5j1201	2455	5	locations	location	NNS
cord-022561-rv5j1201	2455	6	of	of	IN
cord-022561-rv5j1201	2455	7	equine	equine	JJ
cord-022561-rv5j1201	2455	8	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2455	9	are	be	VBP
cord-022561-rv5j1201	2455	10	multicentric	multicentric	JJ
cord-022561-rv5j1201	2455	11	,	,	,
cord-022561-rv5j1201	2455	12	cutaneous	cutaneous	JJ
cord-022561-rv5j1201	2455	13	,	,	,
cord-022561-rv5j1201	2455	14	and	and	CC
cord-022561-rv5j1201	2455	15	gastrointestinal	gastrointestinal	JJ
cord-022561-rv5j1201	2455	16	tract	tract	NN
cord-022561-rv5j1201	2455	17	.	.	.
cord-022561-rv5j1201	2456	1	Multicentric	Multicentric	NNP
cord-022561-rv5j1201	2456	2	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2456	3	,	,	,
cord-022561-rv5j1201	2456	4	defined	define	VBN
cord-022561-rv5j1201	2456	5	as	as	IN
cord-022561-rv5j1201	2456	6	involving	involve	VBG
cord-022561-rv5j1201	2456	7	at	at	RB
cord-022561-rv5j1201	2456	8	least	least	RBS
cord-022561-rv5j1201	2456	9	two	two	CD
cord-022561-rv5j1201	2456	10	organs	organ	NNS
cord-022561-rv5j1201	2456	11	(	(	-LRB-
cord-022561-rv5j1201	2456	12	excluding	exclude	VBG
cord-022561-rv5j1201	2456	13	the	the	DT
cord-022561-rv5j1201	2456	14	regional	regional	JJ
cord-022561-rv5j1201	2456	15	lymph	lymph	NN
cord-022561-rv5j1201	2456	16	nodes	node	NNS
cord-022561-rv5j1201	2456	17	)	)	-RRB-
cord-022561-rv5j1201	2456	18	,	,	,
cord-022561-rv5j1201	2456	19	is	be	VBZ
cord-022561-rv5j1201	2456	20	the	the	DT
cord-022561-rv5j1201	2456	21	most	most	RBS
cord-022561-rv5j1201	2456	22	common	common	JJ
cord-022561-rv5j1201	2456	23	manifestation	manifestation	NN
cord-022561-rv5j1201	2456	24	,	,	,
cord-022561-rv5j1201	2456	25	followed	follow	VBN
cord-022561-rv5j1201	2456	26	by	by	IN
cord-022561-rv5j1201	2456	27	skin	skin	NN
cord-022561-rv5j1201	2456	28	and	and	CC
cord-022561-rv5j1201	2456	29	gastrointestinal	gastrointestinal	JJ
cord-022561-rv5j1201	2456	30	tract	tract	NN
cord-022561-rv5j1201	2456	31	types	type	NNS
cord-022561-rv5j1201	2456	32	.	.	.
cord-022561-rv5j1201	2457	1	Solitary	solitary	JJ
cord-022561-rv5j1201	2457	2	locations	location	NNS
cord-022561-rv5j1201	2457	3	have	have	VBP
cord-022561-rv5j1201	2457	4	been	be	VBN
cord-022561-rv5j1201	2457	5	reported	report	VBN
cord-022561-rv5j1201	2457	6	in	in	IN
cord-022561-rv5j1201	2457	7	the	the	DT
cord-022561-rv5j1201	2457	8	mediastinum	mediastinum	NN
cord-022561-rv5j1201	2457	9	,	,	,
cord-022561-rv5j1201	2457	10	lymph	lymph	NN
cord-022561-rv5j1201	2457	11	nodes	node	NNS
cord-022561-rv5j1201	2457	12	,	,	,
cord-022561-rv5j1201	2457	13	ocular	ocular	JJ
cord-022561-rv5j1201	2457	14	/	/	SYM
cord-022561-rv5j1201	2457	15	orbital	orbital	JJ
cord-022561-rv5j1201	2457	16	region	region	NN
cord-022561-rv5j1201	2457	17	,	,	,
cord-022561-rv5j1201	2457	18	brain	brain	NN
cord-022561-rv5j1201	2457	19	,	,	,
cord-022561-rv5j1201	2457	20	spinal	spinal	JJ
cord-022561-rv5j1201	2457	21	cord	cord	NN
cord-022561-rv5j1201	2457	22	,	,	,
cord-022561-rv5j1201	2457	23	oral	oral	JJ
cord-022561-rv5j1201	2457	24	cavity	cavity	NN
cord-022561-rv5j1201	2457	25	,	,	,
cord-022561-rv5j1201	2457	26	and	and	CC
cord-022561-rv5j1201	2457	27	spleen	spleen	NNS
cord-022561-rv5j1201	2457	28	.	.	.
cord-022561-rv5j1201	2458	1	Of	of	IN
cord-022561-rv5j1201	2458	2	the	the	DT
cord-022561-rv5j1201	2458	3	multicentric	multicentric	JJ
cord-022561-rv5j1201	2458	4	lymphomas	lymphoma	NNS
cord-022561-rv5j1201	2458	5	,	,	,
cord-022561-rv5j1201	2458	6	the	the	DT
cord-022561-rv5j1201	2458	7	most	most	RBS
cord-022561-rv5j1201	2458	8	frequently	frequently	RB
cord-022561-rv5j1201	2458	9	observed	observe	VBN
cord-022561-rv5j1201	2458	10	type	type	NN
cord-022561-rv5j1201	2458	11	is	be	VBZ
cord-022561-rv5j1201	2458	12	T	T	NNP
cord-022561-rv5j1201	2458	13	cell	cell	NN
cord-022561-rv5j1201	2458	14	-	-	HYPH
cord-022561-rv5j1201	2458	15	rich	rich	JJ
cord-022561-rv5j1201	2458	16	large	large	JJ
cord-022561-rv5j1201	2458	17	B	b	NN
cord-022561-rv5j1201	2458	18	cell	cell	NN
cord-022561-rv5j1201	2458	19	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2458	20	(	(	-LRB-
cord-022561-rv5j1201	2458	21	TCRLBCL	TCRLBCL	NNP
cord-022561-rv5j1201	2458	22	)	)	-RRB-
cord-022561-rv5j1201	2458	23	,	,	,
cord-022561-rv5j1201	2458	24	reportedly	reportedly	RB
cord-022561-rv5j1201	2458	25	in	in	IN
cord-022561-rv5j1201	2458	26	one	one	CD
cord-022561-rv5j1201	2458	27	study	study	NN
cord-022561-rv5j1201	2458	28	affecting	affect	VBG
cord-022561-rv5j1201	2458	29	34	34	CD
cord-022561-rv5j1201	2458	30	%	%	NN
cord-022561-rv5j1201	2458	31	of	of	IN
cord-022561-rv5j1201	2458	32	the	the	DT
cord-022561-rv5j1201	2458	33	cases	case	NNS
cord-022561-rv5j1201	2458	34	.	.	.
cord-022561-rv5j1201	2459	1	Peripheral	peripheral	JJ
cord-022561-rv5j1201	2459	2	T	T	NNP
cord-022561-rv5j1201	2459	3	cell	cell	NN
cord-022561-rv5j1201	2459	4	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2459	5	(	(	-LRB-
cord-022561-rv5j1201	2459	6	PTCL	PTCL	NNP
cord-022561-rv5j1201	2459	7	)	)	-RRB-
cord-022561-rv5j1201	2459	8	was	be	VBD
cord-022561-rv5j1201	2459	9	the	the	DT
cord-022561-rv5j1201	2459	10	second	second	JJ
cord-022561-rv5j1201	2459	11	most	most	RBS
cord-022561-rv5j1201	2459	12	common	common	JJ
cord-022561-rv5j1201	2459	13	,	,	,
cord-022561-rv5j1201	2459	14	followed	follow	VBN
cord-022561-rv5j1201	2459	15	by	by	IN
cord-022561-rv5j1201	2459	16	diffuse	diffuse	VB
cord-022561-rv5j1201	2459	17	large	large	JJ
cord-022561-rv5j1201	2459	18	B	b	NN
cord-022561-rv5j1201	2459	19	cell	cell	NN
cord-022561-rv5j1201	2459	20	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2459	21	(	(	-LRB-
cord-022561-rv5j1201	2459	22	DLBCL	DLBCL	NNP
cord-022561-rv5j1201	2459	23	)	)	-RRB-
cord-022561-rv5j1201	2459	24	.	.	.
cord-022561-rv5j1201	2460	1	The	the	DT
cord-022561-rv5j1201	2460	2	most	most	RBS
cord-022561-rv5j1201	2460	3	common	common	JJ
cord-022561-rv5j1201	2460	4	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2460	5	type	type	NN
cord-022561-rv5j1201	2460	6	in	in	IN
cord-022561-rv5j1201	2460	7	the	the	DT
cord-022561-rv5j1201	2460	8	gastrointestinal	gastrointestinal	JJ
cord-022561-rv5j1201	2460	9	tract	tract	NN
cord-022561-rv5j1201	2460	10	is	be	VBZ
cord-022561-rv5j1201	2460	11	also	also	RB
cord-022561-rv5j1201	2460	12	T	T	NNP
cord-022561-rv5j1201	2460	13	cell	cell	NN
cord-022561-rv5j1201	2460	14	-	-	HYPH
cord-022561-rv5j1201	2460	15	rich	rich	JJ
cord-022561-rv5j1201	2460	16	large	large	JJ
cord-022561-rv5j1201	2460	17	B	b	NN
cord-022561-rv5j1201	2460	18	cell	cell	NN
cord-022561-rv5j1201	2460	19	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2460	20	,	,	,
cord-022561-rv5j1201	2460	21	followed	follow	VBN
cord-022561-rv5j1201	2460	22	by	by	IN
cord-022561-rv5j1201	2460	23	enteropathyassociated	enteropathyassociate	VBN
cord-022561-rv5j1201	2460	24	T	T	NNP
cord-022561-rv5j1201	2460	25	cell	cell	NN
cord-022561-rv5j1201	2460	26	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2460	27	.	.	.
cord-022561-rv5j1201	2461	1	Cutaneous	cutaneous	JJ
cord-022561-rv5j1201	2461	2	lymphomas	lymphoma	NNS
cord-022561-rv5j1201	2461	3	in	in	IN
cord-022561-rv5j1201	2461	4	horses	horse	NNS
cord-022561-rv5j1201	2461	5	account	account	VBP
cord-022561-rv5j1201	2461	6	for	for	IN
cord-022561-rv5j1201	2461	7	up	up	IN
cord-022561-rv5j1201	2461	8	to	to	TO
cord-022561-rv5j1201	2461	9	3	3	CD
cord-022561-rv5j1201	2461	10	%	%	NN
cord-022561-rv5j1201	2461	11	of	of	IN
cord-022561-rv5j1201	2461	12	all	all	DT
cord-022561-rv5j1201	2461	13	equine	equine	JJ
cord-022561-rv5j1201	2461	14	skin	skin	NN
cord-022561-rv5j1201	2461	15	tumors	tumor	NNS
cord-022561-rv5j1201	2461	16	.	.	.
cord-022561-rv5j1201	2462	1	T	T	NNP
cord-022561-rv5j1201	2462	2	cell	cell	NN
cord-022561-rv5j1201	2462	3	-	-	HYPH
cord-022561-rv5j1201	2462	4	rich	rich	JJ
cord-022561-rv5j1201	2462	5	large	large	JJ
cord-022561-rv5j1201	2462	6	B	b	NN
cord-022561-rv5j1201	2462	7	cell	cell	NN
cord-022561-rv5j1201	2462	8	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2462	9	is	be	VBZ
cord-022561-rv5j1201	2462	10	again	again	RB
cord-022561-rv5j1201	2462	11	the	the	DT
cord-022561-rv5j1201	2462	12	most	most	RBS
cord-022561-rv5j1201	2462	13	common	common	JJ
cord-022561-rv5j1201	2462	14	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2462	15	subtype	subtype	NN
cord-022561-rv5j1201	2462	16	in	in	IN
cord-022561-rv5j1201	2462	17	the	the	DT
cord-022561-rv5j1201	2462	18	skin	skin	NN
cord-022561-rv5j1201	2462	19	,	,	,
cord-022561-rv5j1201	2462	20	representing	represent	VBG
cord-022561-rv5j1201	2462	21	up	up	IN
cord-022561-rv5j1201	2462	22	to	to	TO
cord-022561-rv5j1201	2462	23	84	84	CD
cord-022561-rv5j1201	2462	24	%	%	NN
cord-022561-rv5j1201	2462	25	of	of	IN
cord-022561-rv5j1201	2462	26	all	all	DT
cord-022561-rv5j1201	2462	27	cutaneous	cutaneous	JJ
cord-022561-rv5j1201	2462	28	lymphomas	lymphoma	NNS
cord-022561-rv5j1201	2462	29	,	,	,
cord-022561-rv5j1201	2462	30	and	and	CC
cord-022561-rv5j1201	2462	31	most	most	RBS
cord-022561-rv5j1201	2462	32	frequently	frequently	RB
cord-022561-rv5j1201	2462	33	presents	present	VBZ
cord-022561-rv5j1201	2462	34	clinically	clinically	RB
cord-022561-rv5j1201	2462	35	as	as	IN
cord-022561-rv5j1201	2462	36	multiple	multiple	JJ
cord-022561-rv5j1201	2462	37	skin	skin	NN
cord-022561-rv5j1201	2462	38	masses	masse	NNS
cord-022561-rv5j1201	2462	39	.	.	.
cord-022561-rv5j1201	2463	1	Cutaneous	cutaneous	JJ
cord-022561-rv5j1201	2463	2	T	t	NN
cord-022561-rv5j1201	2463	3	cell	cell	NN
cord-022561-rv5j1201	2463	4	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2463	5	(	(	-LRB-
cord-022561-rv5j1201	2463	6	CTCL	CTCL	NNP
cord-022561-rv5j1201	2463	7	)	)	-RRB-
cord-022561-rv5j1201	2463	8	is	be	VBZ
cord-022561-rv5j1201	2463	9	the	the	DT
cord-022561-rv5j1201	2463	10	second	second	JJ
cord-022561-rv5j1201	2463	11	most	most	RBS
cord-022561-rv5j1201	2463	12	common	common	JJ
cord-022561-rv5j1201	2463	13	form	form	NN
cord-022561-rv5j1201	2463	14	and	and	CC
cord-022561-rv5j1201	2463	15	arises	arise	VBZ
cord-022561-rv5j1201	2463	16	as	as	IN
cord-022561-rv5j1201	2463	17	smaller	small	JJR
cord-022561-rv5j1201	2463	18	solitary	solitary	JJ
cord-022561-rv5j1201	2463	19	nodules	nodule	NNS
cord-022561-rv5j1201	2463	20	.	.	.
cord-022561-rv5j1201	2464	1	Thoroughbreds	thoroughbred	NNS
cord-022561-rv5j1201	2464	2	may	may	MD
cord-022561-rv5j1201	2464	3	have	have	VB
cord-022561-rv5j1201	2464	4	a	a	DT
cord-022561-rv5j1201	2464	5	higher	high	JJR
cord-022561-rv5j1201	2464	6	incidence	incidence	NN
cord-022561-rv5j1201	2464	7	of	of	IN
cord-022561-rv5j1201	2464	8	cutaneous	cutaneous	JJ
cord-022561-rv5j1201	2464	9	T	T	NNP
cord-022561-rv5j1201	2464	10	cell	cell	NN
cord-022561-rv5j1201	2464	11	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2464	12	compared	compare	VBN
cord-022561-rv5j1201	2464	13	to	to	IN
cord-022561-rv5j1201	2464	14	other	other	JJ
cord-022561-rv5j1201	2464	15	breeds	breed	NNS
cord-022561-rv5j1201	2464	16	.	.	.
cord-022561-rv5j1201	2465	1	Overall	overall	RB
cord-022561-rv5j1201	2465	2	,	,	,
cord-022561-rv5j1201	2465	3	horses	horse	NNS
cord-022561-rv5j1201	2465	4	with	with	IN
cord-022561-rv5j1201	2465	5	cutaneous	cutaneous	JJ
cord-022561-rv5j1201	2465	6	T	T	NNP
cord-022561-rv5j1201	2465	7	cell	cell	NN
cord-022561-rv5j1201	2465	8	-	-	HYPH
cord-022561-rv5j1201	2465	9	rich	rich	JJ
cord-022561-rv5j1201	2465	10	large	large	JJ
cord-022561-rv5j1201	2465	11	B	b	NN
cord-022561-rv5j1201	2465	12	cell	cell	NN
cord-022561-rv5j1201	2465	13	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2465	14	appear	appear	VBP
cord-022561-rv5j1201	2465	15	to	to	TO
cord-022561-rv5j1201	2465	16	have	have	VB
cord-022561-rv5j1201	2465	17	a	a	DT
cord-022561-rv5j1201	2465	18	longer	long	JJR
cord-022561-rv5j1201	2465	19	survival	survival	NN
cord-022561-rv5j1201	2465	20	time	time	NN
cord-022561-rv5j1201	2465	21	than	than	IN
cord-022561-rv5j1201	2465	22	horses	horse	NNS
cord-022561-rv5j1201	2465	23	with	with	IN
cord-022561-rv5j1201	2465	24	other	other	JJ
cord-022561-rv5j1201	2465	25	types	type	NNS
cord-022561-rv5j1201	2465	26	of	of	IN
cord-022561-rv5j1201	2465	27	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2465	28	of	of	IN
cord-022561-rv5j1201	2465	29	the	the	DT
cord-022561-rv5j1201	2465	30	skin	skin	NN
cord-022561-rv5j1201	2465	31	.	.	.
cord-022561-rv5j1201	2466	1	Progesterone	progesterone	NN
cord-022561-rv5j1201	2466	2	receptor	receptor	NN
cord-022561-rv5j1201	2466	3	-	-	HYPH
cord-022561-rv5j1201	2466	4	positive	positive	JJ
cord-022561-rv5j1201	2466	5	lymphomas	lymphoma	NNS
cord-022561-rv5j1201	2466	6	have	have	VBP
cord-022561-rv5j1201	2466	7	also	also	RB
cord-022561-rv5j1201	2466	8	been	be	VBN
cord-022561-rv5j1201	2466	9	identified	identify	VBN
cord-022561-rv5j1201	2466	10	in	in	IN
cord-022561-rv5j1201	2466	11	horses	horse	NNS
cord-022561-rv5j1201	2466	12	,	,	,
cord-022561-rv5j1201	2466	13	and	and	CC
cord-022561-rv5j1201	2466	14	there	there	EX
cord-022561-rv5j1201	2466	15	is	be	VBZ
cord-022561-rv5j1201	2466	16	one	one	CD
cord-022561-rv5j1201	2466	17	report	report	NN
cord-022561-rv5j1201	2466	18	of	of	IN
cord-022561-rv5j1201	2466	19	subcutaneous	subcutaneous	JJ
cord-022561-rv5j1201	2466	20	tumor	tumor	NN
cord-022561-rv5j1201	2466	21	regression	regression	NN
cord-022561-rv5j1201	2466	22	following	follow	VBG
cord-022561-rv5j1201	2466	23	removal	removal	NN
cord-022561-rv5j1201	2466	24	of	of	IN
cord-022561-rv5j1201	2466	25	an	an	DT
cord-022561-rv5j1201	2466	26	ovarian	ovarian	JJ
cord-022561-rv5j1201	2466	27	granulosa	granulosa	NN
cord-022561-rv5j1201	2466	28	-	-	HYPH
cord-022561-rv5j1201	2466	29	theca	theca	NN
cord-022561-rv5j1201	2466	30	cell	cell	NN
cord-022561-rv5j1201	2466	31	tumor	tumor	NN
cord-022561-rv5j1201	2466	32	.	.	.
cord-022561-rv5j1201	2467	1	There	there	EX
cord-022561-rv5j1201	2467	2	may	may	MD
cord-022561-rv5j1201	2467	3	be	be	VB
cord-022561-rv5j1201	2467	4	an	an	DT
cord-022561-rv5j1201	2467	5	increased	increase	VBN
cord-022561-rv5j1201	2467	6	frequency	frequency	NN
cord-022561-rv5j1201	2467	7	of	of	IN
cord-022561-rv5j1201	2467	8	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2467	9	in	in	IN
cord-022561-rv5j1201	2467	10	horses	horse	NNS
cord-022561-rv5j1201	2467	11	diagnosed	diagnose	VBN
cord-022561-rv5j1201	2467	12	with	with	IN
cord-022561-rv5j1201	2467	13	equine	equine	JJ
cord-022561-rv5j1201	2467	14	herpesvirus	herpesvirus	NN
cord-022561-rv5j1201	2467	15	5	5	CD
cord-022561-rv5j1201	2467	16	(	(	-LRB-
cord-022561-rv5j1201	2467	17	EHV-5	EHV-5	NNP
cord-022561-rv5j1201	2467	18	,	,	,
cord-022561-rv5j1201	2467	19	gammaherpesvirus	gammaherpesvirus	NNP
cord-022561-rv5j1201	2467	20	)	)	-RRB-
cord-022561-rv5j1201	2467	21	,	,	,
cord-022561-rv5j1201	2467	22	when	when	WRB
cord-022561-rv5j1201	2467	23	compared	compare	VBN
cord-022561-rv5j1201	2467	24	to	to	IN
cord-022561-rv5j1201	2467	25	healthy	healthy	JJ
cord-022561-rv5j1201	2467	26	horses	horse	NNS
cord-022561-rv5j1201	2467	27	,	,	,
cord-022561-rv5j1201	2467	28	although	although	IN
cord-022561-rv5j1201	2467	29	the	the	DT
cord-022561-rv5j1201	2467	30	exact	exact	JJ
cord-022561-rv5j1201	2467	31	cause	cause	NN
cord-022561-rv5j1201	2467	32	-	-	HYPH
cord-022561-rv5j1201	2467	33	effect	effect	NN
cord-022561-rv5j1201	2467	34	role	role	NN
cord-022561-rv5j1201	2467	35	of	of	IN
cord-022561-rv5j1201	2467	36	this	this	DT
cord-022561-rv5j1201	2467	37	observation	observation	NN
cord-022561-rv5j1201	2467	38	in	in	IN
cord-022561-rv5j1201	2467	39	lymphomagenesis	lymphomagenesis	NNP
cord-022561-rv5j1201	2467	40	5	5	CD
cord-022561-rv5j1201	2467	41	is	be	VBZ
cord-022561-rv5j1201	2467	42	not	not	RB
cord-022561-rv5j1201	2467	43	yet	yet	RB
cord-022561-rv5j1201	2467	44	known	know	VBN
cord-022561-rv5j1201	2467	45	.	.	.
cord-022561-rv5j1201	2468	1	Histologically	histologically	RB
cord-022561-rv5j1201	2468	2	,	,	,
cord-022561-rv5j1201	2468	3	the	the	DT
cord-022561-rv5j1201	2468	4	hallmark	hallmark	NN
cord-022561-rv5j1201	2468	5	features	feature	NNS
cord-022561-rv5j1201	2468	6	of	of	IN
cord-022561-rv5j1201	2468	7	T	T	NNP
cord-022561-rv5j1201	2468	8	cell	cell	NN
cord-022561-rv5j1201	2468	9	-	-	HYPH
cord-022561-rv5j1201	2468	10	rich	rich	JJ
cord-022561-rv5j1201	2468	11	large	large	JJ
cord-022561-rv5j1201	2468	12	B	b	NN
cord-022561-rv5j1201	2468	13	cell	cell	NN
cord-022561-rv5j1201	2468	14	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2468	15	include	include	VBP
cord-022561-rv5j1201	2468	16	a	a	DT
cord-022561-rv5j1201	2468	17	majority	majority	NN
cord-022561-rv5j1201	2468	18	of	of	IN
cord-022561-rv5j1201	2468	19	small	small	JJ
cord-022561-rv5j1201	2468	20	(	(	-LRB-
cord-022561-rv5j1201	2468	21	nuclei	nucleus	NNS
cord-022561-rv5j1201	2468	22	approximately	approximately	RB
cord-022561-rv5j1201	2468	23	the	the	DT
cord-022561-rv5j1201	2468	24	size	size	NN
cord-022561-rv5j1201	2468	25	of	of	IN
cord-022561-rv5j1201	2468	26	an	an	DT
cord-022561-rv5j1201	2468	27	RBC	RBC	NNP
cord-022561-rv5j1201	2468	28	)	)	-RRB-
cord-022561-rv5j1201	2468	29	,	,	,
cord-022561-rv5j1201	2468	30	reactive	reactive	JJ
cord-022561-rv5j1201	2468	31	,	,	,
cord-022561-rv5j1201	2468	32	mature	mature	JJ
cord-022561-rv5j1201	2468	33	T	t	NN
cord-022561-rv5j1201	2468	34	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	2468	35	admixed	admix	VBN
cord-022561-rv5j1201	2468	36	with	with	IN
cord-022561-rv5j1201	2468	37	a	a	DT
cord-022561-rv5j1201	2468	38	neoplastic	neoplastic	JJ
cord-022561-rv5j1201	2468	39	population	population	NN
cord-022561-rv5j1201	2468	40	of	of	IN
cord-022561-rv5j1201	2468	41	large	large	JJ
cord-022561-rv5j1201	2468	42	B	b	NN
cord-022561-rv5j1201	2468	43	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	2468	44	whose	whose	WP$
cord-022561-rv5j1201	2468	45	nuclei	nucleus	NNS
cord-022561-rv5j1201	2468	46	are	be	VBP
cord-022561-rv5j1201	2468	47	two	two	CD
cord-022561-rv5j1201	2468	48	to	to	TO
cord-022561-rv5j1201	2468	49	three	three	CD
cord-022561-rv5j1201	2468	50	times	time	NNS
cord-022561-rv5j1201	2468	51	the	the	DT
cord-022561-rv5j1201	2468	52	diameter	diameter	NN
cord-022561-rv5j1201	2468	53	of	of	IN
cord-022561-rv5j1201	2468	54	an	an	DT
cord-022561-rv5j1201	2468	55	equine	equine	JJ
cord-022561-rv5j1201	2468	56	RBC	RBC	NNP
cord-022561-rv5j1201	2468	57	.	.	.
cord-022561-rv5j1201	2469	1	These	these	DT
cord-022561-rv5j1201	2469	2	large	large	JJ
cord-022561-rv5j1201	2469	3	atypical	atypical	JJ
cord-022561-rv5j1201	2469	4	cells	cell	NNS
cord-022561-rv5j1201	2469	5	are	be	VBP
cord-022561-rv5j1201	2469	6	often	often	RB
cord-022561-rv5j1201	2469	7	binucleated	binucleate	VBN
cord-022561-rv5j1201	2469	8	and	and	CC
cord-022561-rv5j1201	2469	9	have	have	VBP
cord-022561-rv5j1201	2469	10	prominent	prominent	JJ
cord-022561-rv5j1201	2469	11	eosinophilic	eosinophilic	JJ
cord-022561-rv5j1201	2469	12	nucleoli	nucleolus	NNS
cord-022561-rv5j1201	2470	1	(	(	-LRB-
cord-022561-rv5j1201	2470	2	Fig	Fig	NNP
cord-022561-rv5j1201	2470	3	.	.	.
cord-022561-rv5j1201	2470	4	13	13	CD
cord-022561-rv5j1201	2470	5	-	-	SYM
cord-022561-rv5j1201	2470	6	86	86	CD
cord-022561-rv5j1201	2470	7	)	)	-RRB-
cord-022561-rv5j1201	2470	8	.	.	.
cord-022561-rv5j1201	2471	1	The	the	DT
cord-022561-rv5j1201	2471	2	large	large	JJ
cord-022561-rv5j1201	2471	3	cells	cell	NNS
cord-022561-rv5j1201	2471	4	may	may	MD
cord-022561-rv5j1201	2471	5	be	be	VB
cord-022561-rv5j1201	2471	6	observed	observe	VBN
cord-022561-rv5j1201	2471	7	in	in	IN
cord-022561-rv5j1201	2471	8	mitosis	mitosis	NN
cord-022561-rv5j1201	2471	9	or	or	CC
cord-022561-rv5j1201	2471	10	in	in	IN
cord-022561-rv5j1201	2471	11	necrosis	necrosis	NN
cord-022561-rv5j1201	2471	12	as	as	IN
cord-022561-rv5j1201	2471	13	single	single	JJ
cord-022561-rv5j1201	2471	14	cells	cell	NNS
cord-022561-rv5j1201	2471	15	with	with	IN
cord-022561-rv5j1201	2471	16	retracted	retract	VBN
cord-022561-rv5j1201	2471	17	cytoplasm	cytoplasm	NN
cord-022561-rv5j1201	2471	18	and	and	CC
cord-022561-rv5j1201	2471	19	pyknotic	pyknotic	JJ
cord-022561-rv5j1201	2471	20	nuclei	nucleus	NNS
cord-022561-rv5j1201	2471	21	.	.	.
cord-022561-rv5j1201	2472	1	T	T	NNP
cord-022561-rv5j1201	2472	2	cell	cell	NN
cord-022561-rv5j1201	2472	3	-	-	HYPH
cord-022561-rv5j1201	2472	4	rich	rich	JJ
cord-022561-rv5j1201	2472	5	large	large	JJ
cord-022561-rv5j1201	2472	6	B	b	NN
cord-022561-rv5j1201	2472	7	cell	cell	NN
cord-022561-rv5j1201	2472	8	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2472	9	is	be	VBZ
cord-022561-rv5j1201	2472	10	often	often	RB
cord-022561-rv5j1201	2472	11	accompanied	accompany	VBN
cord-022561-rv5j1201	2472	12	by	by	IN
cord-022561-rv5j1201	2472	13	the	the	DT
cord-022561-rv5j1201	2472	14	presence	presence	NN
cord-022561-rv5j1201	2472	15	of	of	IN
cord-022561-rv5j1201	2472	16	a	a	DT
cord-022561-rv5j1201	2472	17	dense	dense	JJ
cord-022561-rv5j1201	2472	18	fibrovascular	fibrovascular	JJ
cord-022561-rv5j1201	2472	19	network	network	NN
cord-022561-rv5j1201	2472	20	.	.	.
cord-022561-rv5j1201	2473	1	Johne	Johne	NNP
cord-022561-rv5j1201	2473	2	's	's	POS
cord-022561-rv5j1201	2473	3	disease	disease	NN
cord-022561-rv5j1201	2473	4	primarily	primarily	RB
cord-022561-rv5j1201	2473	5	affects	affect	VBZ
cord-022561-rv5j1201	2473	6	domestic	domestic	JJ
cord-022561-rv5j1201	2473	7	and	and	CC
cord-022561-rv5j1201	2473	8	wild	wild	JJ
cord-022561-rv5j1201	2473	9	ruminants	ruminant	NNS
cord-022561-rv5j1201	2473	10	(	(	-LRB-
cord-022561-rv5j1201	2473	11	and	and	CC
cord-022561-rv5j1201	2473	12	rarely	rarely	RB
cord-022561-rv5j1201	2473	13	pigs	pig	NNS
cord-022561-rv5j1201	2473	14	and	and	CC
cord-022561-rv5j1201	2473	15	horses	horse	NNS
cord-022561-rv5j1201	2473	16	)	)	-RRB-
cord-022561-rv5j1201	2473	17	and	and	CC
cord-022561-rv5j1201	2473	18	is	be	VBZ
cord-022561-rv5j1201	2473	19	due	due	JJ
cord-022561-rv5j1201	2473	20	to	to	IN
cord-022561-rv5j1201	2473	21	infection	infection	NN
cord-022561-rv5j1201	2473	22	by	by	IN
cord-022561-rv5j1201	2473	23	MAP	MAP	NNP
cord-022561-rv5j1201	2473	24	.	.	.
cord-022561-rv5j1201	2474	1	The	the	DT
cord-022561-rv5j1201	2474	2	characteristic	characteristic	JJ
cord-022561-rv5j1201	2474	3	lesions	lesion	NNS
cord-022561-rv5j1201	2474	4	include	include	VBP
cord-022561-rv5j1201	2474	5	granulomatous	granulomatous	JJ
cord-022561-rv5j1201	2474	6	enteritis	enteritis	NN
cord-022561-rv5j1201	2474	7	usually	usually	RB
cord-022561-rv5j1201	2474	8	confined	confine	VBN
cord-022561-rv5j1201	2474	9	to	to	IN
cord-022561-rv5j1201	2474	10	the	the	DT
cord-022561-rv5j1201	2474	11	ileum	ileum	NN
cord-022561-rv5j1201	2474	12	,	,	,
cord-022561-rv5j1201	2474	13	cecum	cecum	NN
cord-022561-rv5j1201	2474	14	,	,	,
cord-022561-rv5j1201	2474	15	and	and	CC
cord-022561-rv5j1201	2474	16	proximal	proximal	JJ
cord-022561-rv5j1201	2474	17	colon	colon	NN
cord-022561-rv5j1201	2474	18	;	;	:
cord-022561-rv5j1201	2474	19	lymphangitis	lymphangitis	NNP
cord-022561-rv5j1201	2474	20	;	;	:
cord-022561-rv5j1201	2474	21	and	and	CC
cord-022561-rv5j1201	2474	22	lymphadenitis	lymphadenitis	NN
cord-022561-rv5j1201	2474	23	of	of	IN
cord-022561-rv5j1201	2474	24	regional	regional	JJ
cord-022561-rv5j1201	2474	25	lymph	lymph	NN
cord-022561-rv5j1201	2474	26	nodes	node	NNS
cord-022561-rv5j1201	2474	27	(	(	-LRB-
cord-022561-rv5j1201	2474	28	see	see	VB
cord-022561-rv5j1201	2474	29	Fig	Fig	NNP
cord-022561-rv5j1201	2474	30	.	.	.
cord-022561-rv5j1201	2475	1	13	13	CD
cord-022561-rv5j1201	2475	2	-	-	SYM
cord-022561-rv5j1201	2475	3	82	82	CD
cord-022561-rv5j1201	2475	4	)	)	-RRB-
cord-022561-rv5j1201	2475	5	.	.	.
cord-022561-rv5j1201	2476	1	The	the	DT
cord-022561-rv5j1201	2476	2	bacteria	bacteria	NNS
cord-022561-rv5j1201	2476	3	are	be	VBP
cord-022561-rv5j1201	2476	4	ingested	ingest	VBN
cord-022561-rv5j1201	2476	5	,	,	,
cord-022561-rv5j1201	2476	6	engulfed	engulf	VBN
cord-022561-rv5j1201	2476	7	by	by	IN
cord-022561-rv5j1201	2476	8	the	the	DT
cord-022561-rv5j1201	2476	9	M	M	NNP
cord-022561-rv5j1201	2476	10	cells	cell	NNS
cord-022561-rv5j1201	2476	11	overlying	overlie	VBG
cord-022561-rv5j1201	2476	12	Peyer	Peyer	NNP
cord-022561-rv5j1201	2476	13	's	's	POS
cord-022561-rv5j1201	2476	14	patches	patch	NNS
cord-022561-rv5j1201	2476	15	,	,	,
cord-022561-rv5j1201	2476	16	and	and	CC
cord-022561-rv5j1201	2476	17	then	then	RB
cord-022561-rv5j1201	2476	18	transported	transport	VBN
cord-022561-rv5j1201	2476	19	to	to	IN
cord-022561-rv5j1201	2476	20	macrophages	macrophage	NNS
cord-022561-rv5j1201	2476	21	in	in	IN
cord-022561-rv5j1201	2476	22	the	the	DT
cord-022561-rv5j1201	2476	23	lamina	lamina	JJ
cord-022561-rv5j1201	2476	24	propria	propria	NNP
cord-022561-rv5j1201	2476	25	and	and	CC
cord-022561-rv5j1201	2476	26	submucosa	submucosa	NNP
cord-022561-rv5j1201	2476	27	.	.	.
cord-022561-rv5j1201	2477	1	Among	among	IN
cord-022561-rv5j1201	2477	2	cattle	cattle	NNS
cord-022561-rv5j1201	2477	3	,	,	,
cord-022561-rv5j1201	2477	4	sheep	sheep	NNS
cord-022561-rv5j1201	2477	5	,	,	,
cord-022561-rv5j1201	2477	6	goats	goat	NNS
cord-022561-rv5j1201	2477	7	,	,	,
cord-022561-rv5j1201	2477	8	and	and	CC
cord-022561-rv5j1201	2477	9	wild	wild	JJ
cord-022561-rv5j1201	2477	10	ruminants	ruminant	NNS
cord-022561-rv5j1201	2477	11	,	,	,
cord-022561-rv5j1201	2477	12	there	there	EX
cord-022561-rv5j1201	2477	13	is	be	VBZ
cord-022561-rv5j1201	2477	14	wide	wide	JJ
cord-022561-rv5j1201	2477	15	variation	variation	NN
cord-022561-rv5j1201	2477	16	in	in	IN
cord-022561-rv5j1201	2477	17	the	the	DT
cord-022561-rv5j1201	2477	18	severity	severity	NN
cord-022561-rv5j1201	2477	19	,	,	,
cord-022561-rv5j1201	2477	20	distribution	distribution	NN
cord-022561-rv5j1201	2477	21	of	of	IN
cord-022561-rv5j1201	2477	22	lesions	lesion	NNS
cord-022561-rv5j1201	2477	23	,	,	,
cord-022561-rv5j1201	2477	24	primary	primary	JJ
cord-022561-rv5j1201	2477	25	inflammatory	inflammatory	JJ
cord-022561-rv5j1201	2477	26	cell	cell	NN
cord-022561-rv5j1201	2477	27	type	type	NN
cord-022561-rv5j1201	2477	28	(	(	-LRB-
cord-022561-rv5j1201	2477	29	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	2477	30	,	,	,
cord-022561-rv5j1201	2477	31	epithelioid	epithelioid	NNP
cord-022561-rv5j1201	2477	32	macrophages	macrophage	NNS
cord-022561-rv5j1201	2477	33	,	,	,
cord-022561-rv5j1201	2477	34	multinucleated	multinucleate	VBN
cord-022561-rv5j1201	2477	35	giant	giant	JJ
cord-022561-rv5j1201	2477	36	cells	cell	NNS
cord-022561-rv5j1201	2477	37	)	)	-RRB-
cord-022561-rv5j1201	2477	38	,	,	,
cord-022561-rv5j1201	2477	39	and	and	CC
cord-022561-rv5j1201	2477	40	numbers	number	NNS
cord-022561-rv5j1201	2477	41	of	of	IN
cord-022561-rv5j1201	2477	42	bacteria	bacteria	NNS
cord-022561-rv5j1201	2477	43	within	within	IN
cord-022561-rv5j1201	2477	44	lesions	lesion	NNS
cord-022561-rv5j1201	2477	45	(	(	-LRB-
cord-022561-rv5j1201	2477	46	multibacillary	multibacillary	JJ
cord-022561-rv5j1201	2477	47	or	or	CC
cord-022561-rv5j1201	2477	48	paucibacillary	paucibacillary	NNP
cord-022561-rv5j1201	2477	49	)	)	-RRB-
cord-022561-rv5j1201	2477	50	.	.	.
cord-022561-rv5j1201	2478	1	Histologically	histologically	RB
cord-022561-rv5j1201	2478	2	,	,	,
cord-022561-rv5j1201	2478	3	the	the	DT
cord-022561-rv5j1201	2478	4	architecture	architecture	NN
cord-022561-rv5j1201	2478	5	of	of	IN
cord-022561-rv5j1201	2478	6	the	the	DT
cord-022561-rv5j1201	2478	7	ileocecal	ileocecal	JJ
cord-022561-rv5j1201	2478	8	lymph	lymph	NN
cord-022561-rv5j1201	2478	9	nodes	node	NNS
cord-022561-rv5j1201	2478	10	may	may	MD
cord-022561-rv5j1201	2478	11	be	be	VB
cord-022561-rv5j1201	2478	12	partially	partially	RB
cord-022561-rv5j1201	2478	13	replaced	replace	VBN
cord-022561-rv5j1201	2478	14	by	by	IN
cord-022561-rv5j1201	2478	15	aggregates	aggregate	NNS
cord-022561-rv5j1201	2478	16	of	of	IN
cord-022561-rv5j1201	2478	17	epithelioid	epithelioid	NNP
cord-022561-rv5j1201	2478	18	 	 	_SP
cord-022561-rv5j1201	2478	19	Postweaning	Postweaning	NNP
cord-022561-rv5j1201	2478	20	Multisystem	Multisystem	NNP
cord-022561-rv5j1201	2478	21	Wasting	waste	VBG
cord-022561-rv5j1201	2478	22	Syndrome	Syndrome	NNP
cord-022561-rv5j1201	2478	23	PCV2	PCV2	NNP
cord-022561-rv5j1201	2478	24	,	,	,
cord-022561-rv5j1201	2478	25	a	a	DT
cord-022561-rv5j1201	2478	26	small	small	JJ
cord-022561-rv5j1201	2478	27	single	single	JJ
cord-022561-rv5j1201	2478	28	-	-	HYPH
cord-022561-rv5j1201	2478	29	stranded	strand	VBN
cord-022561-rv5j1201	2478	30	DNA	dna	NN
cord-022561-rv5j1201	2478	31	virus	virus	NN
cord-022561-rv5j1201	2478	32	,	,	,
cord-022561-rv5j1201	2478	33	is	be	VBZ
cord-022561-rv5j1201	2478	34	highly	highly	RB
cord-022561-rv5j1201	2478	35	prevalent	prevalent	JJ
cord-022561-rv5j1201	2478	36	in	in	IN
cord-022561-rv5j1201	2478	37	the	the	DT
cord-022561-rv5j1201	2478	38	domestic	domestic	JJ
cord-022561-rv5j1201	2478	39	pig	pig	NN
cord-022561-rv5j1201	2478	40	population	population	NN
cord-022561-rv5j1201	2478	41	.	.	.
cord-022561-rv5j1201	2479	1	Several	several	JJ
cord-022561-rv5j1201	2479	2	clinical	clinical	JJ
cord-022561-rv5j1201	2479	3	syndromes	syndrome	NNS
cord-022561-rv5j1201	2479	4	are	be	VBP
cord-022561-rv5j1201	2479	5	attributed	attribute	VBN
cord-022561-rv5j1201	2479	6	to	to	IN
cord-022561-rv5j1201	2479	7	PCV2	pcv2	JJ
cord-022561-rv5j1201	2479	8	infection	infection	NN
cord-022561-rv5j1201	2479	9	and	and	CC
cord-022561-rv5j1201	2479	10	collectively	collectively	RB
cord-022561-rv5j1201	2479	11	termed	term	VBN
cord-022561-rv5j1201	2479	12	PCV	pcv	NN
cord-022561-rv5j1201	2479	13	-	-	HYPH
cord-022561-rv5j1201	2479	14	associated	associate	VBN
cord-022561-rv5j1201	2479	15	diseases	disease	NNS
cord-022561-rv5j1201	2479	16	(	(	-LRB-
cord-022561-rv5j1201	2479	17	PCVADs	pcvad	NNS
cord-022561-rv5j1201	2479	18	)	)	-RRB-
cord-022561-rv5j1201	2479	19	.	.	.
cord-022561-rv5j1201	2480	1	These	these	DT
cord-022561-rv5j1201	2480	2	include	include	VBP
cord-022561-rv5j1201	2480	3	postweaning	postweane	VBG
cord-022561-rv5j1201	2480	4	multisystemic	multisystemic	NNP
cord-022561-rv5j1201	2480	5	wasting	waste	VBG
cord-022561-rv5j1201	2480	6	syndrome	syndrome	NN
cord-022561-rv5j1201	2480	7	(	(	-LRB-
cord-022561-rv5j1201	2480	8	PMWS	PMWS	NNP
cord-022561-rv5j1201	2480	9	)	)	-RRB-
cord-022561-rv5j1201	2480	10	,	,	,
cord-022561-rv5j1201	2480	11	porcine	porcine	JJ
cord-022561-rv5j1201	2480	12	respiratory	respiratory	JJ
cord-022561-rv5j1201	2480	13	disease	disease	NN
cord-022561-rv5j1201	2480	14	complex	complex	NN
cord-022561-rv5j1201	2480	15	(	(	-LRB-
cord-022561-rv5j1201	2480	16	PRDC	PRDC	NNP
cord-022561-rv5j1201	2480	17	)	)	-RRB-
cord-022561-rv5j1201	2480	18	,	,	,
cord-022561-rv5j1201	2480	19	porcine	porcine	JJ
cord-022561-rv5j1201	2480	20	dermatitis	dermatitis	NN
cord-022561-rv5j1201	2480	21	and	and	CC
cord-022561-rv5j1201	2480	22	nephropathy	nephropathy	NN
cord-022561-rv5j1201	2480	23	syndrome	syndrome	NN
cord-022561-rv5j1201	2480	24	,	,	,
cord-022561-rv5j1201	2480	25	and	and	CC
cord-022561-rv5j1201	2480	26	enteric	enteric	JJ
cord-022561-rv5j1201	2480	27	disease	disease	NN
cord-022561-rv5j1201	2480	28	(	(	-LRB-
cord-022561-rv5j1201	2480	29	see	see	VB
cord-022561-rv5j1201	2480	30	Chapters	chapter	NNS
cord-022561-rv5j1201	2480	31	4	4	CD
cord-022561-rv5j1201	2480	32	and	and	CC
cord-022561-rv5j1201	2480	33	9	9	CD
cord-022561-rv5j1201	2480	34	)	)	-RRB-
cord-022561-rv5j1201	2480	35	.	.	.
cord-022561-rv5j1201	2481	1	The	the	DT
cord-022561-rv5j1201	2481	2	major	major	JJ
cord-022561-rv5j1201	2481	3	postmortem	postmortem	JJ
cord-022561-rv5j1201	2481	4	findings	finding	NNS
cord-022561-rv5j1201	2481	5	of	of	IN
cord-022561-rv5j1201	2481	6	postweaning	postweane	VBG
cord-022561-rv5j1201	2481	7	multisystemic	multisystemic	NNP
cord-022561-rv5j1201	2481	8	wasting	waste	VBG
cord-022561-rv5j1201	2481	9	syndrome	syndrome	NN
cord-022561-rv5j1201	2481	10	are	be	VBP
cord-022561-rv5j1201	2481	11	poor	poor	JJ
cord-022561-rv5j1201	2481	12	body	body	NN
cord-022561-rv5j1201	2481	13	condition	condition	NN
cord-022561-rv5j1201	2481	14	,	,	,
cord-022561-rv5j1201	2481	15	enlarged	enlarged	JJ
cord-022561-rv5j1201	2481	16	lymph	lymph	NN
cord-022561-rv5j1201	2481	17	nodes	node	NNS
cord-022561-rv5j1201	2481	18	,	,	,
cord-022561-rv5j1201	2481	19	and	and	CC
cord-022561-rv5j1201	2481	20	interstitial	interstitial	JJ
cord-022561-rv5j1201	2481	21	pneumonia	pneumonia	NN
cord-022561-rv5j1201	2481	22	.	.	.
cord-022561-rv5j1201	2482	1	The	the	DT
cord-022561-rv5j1201	2482	2	lesions	lesion	NNS
cord-022561-rv5j1201	2482	3	of	of	IN
cord-022561-rv5j1201	2482	4	the	the	DT
cord-022561-rv5j1201	2482	5	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	2482	6	system	system	NN
cord-022561-rv5j1201	2482	7	are	be	VBP
cord-022561-rv5j1201	2482	8	commonly	commonly	RB
cord-022561-rv5j1201	2482	9	observed	observe	VBN
cord-022561-rv5j1201	2482	10	in	in	IN
cord-022561-rv5j1201	2482	11	the	the	DT
cord-022561-rv5j1201	2482	12	tonsil	tonsil	NN
cord-022561-rv5j1201	2482	13	,	,	,
cord-022561-rv5j1201	2482	14	spleen	spleen	NNS
cord-022561-rv5j1201	2482	15	,	,	,
cord-022561-rv5j1201	2482	16	Peyer	Peyer	NNP
cord-022561-rv5j1201	2482	17	's	's	POS
cord-022561-rv5j1201	2482	18	patches	patch	NNS
cord-022561-rv5j1201	2482	19	,	,	,
cord-022561-rv5j1201	2482	20	and	and	CC
cord-022561-rv5j1201	2482	21	lymph	lymph	NN
cord-022561-rv5j1201	2482	22	nodes	node	NNS
cord-022561-rv5j1201	2482	23	.	.	.
cord-022561-rv5j1201	2483	1	Some	some	DT
cord-022561-rv5j1201	2483	2	pigs	pig	NNS
cord-022561-rv5j1201	2483	3	have	have	VBP
cord-022561-rv5j1201	2483	4	all	all	DT
cord-022561-rv5j1201	2483	5	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	2483	6	tissues	tissue	NNS
cord-022561-rv5j1201	2483	7	affected	affect	VBN
cord-022561-rv5j1201	2483	8	,	,	,
cord-022561-rv5j1201	2483	9	whereas	whereas	IN
cord-022561-rv5j1201	2483	10	others	other	NNS
cord-022561-rv5j1201	2483	11	may	may	MD
cord-022561-rv5j1201	2483	12	have	have	VB
cord-022561-rv5j1201	2483	13	only	only	RB
cord-022561-rv5j1201	2483	14	one	one	CD
cord-022561-rv5j1201	2483	15	or	or	CC
cord-022561-rv5j1201	2483	16	two	two	CD
cord-022561-rv5j1201	2483	17	affected	affected	JJ
cord-022561-rv5j1201	2483	18	lymph	lymph	NN
cord-022561-rv5j1201	2483	19	nodes	node	NNS
cord-022561-rv5j1201	2483	20	.	.	.
cord-022561-rv5j1201	2484	1	The	the	DT
cord-022561-rv5j1201	2484	2	characteristic	characteristic	JJ
cord-022561-rv5j1201	2484	3	microscopic	microscopic	JJ
cord-022561-rv5j1201	2484	4	lesions	lesion	NNS
cord-022561-rv5j1201	2484	5	are	be	VBP
cord-022561-rv5j1201	2484	6	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	2484	7	depletion	depletion	NN
cord-022561-rv5j1201	2484	8	of	of	IN
cord-022561-rv5j1201	2484	9	both	both	DT
cord-022561-rv5j1201	2484	10	follicles	follicle	NNS
cord-022561-rv5j1201	2484	11	and	and	CC
cord-022561-rv5j1201	2484	12	paracortex	paracortex	NN
cord-022561-rv5j1201	2484	13	with	with	IN
cord-022561-rv5j1201	2484	14	replacement	replacement	NN
cord-022561-rv5j1201	2484	15	by	by	IN
cord-022561-rv5j1201	2484	16	histiocytes	histiocyte	NNS
cord-022561-rv5j1201	2484	17	,	,	,
cord-022561-rv5j1201	2484	18	mild	mild	JJ
cord-022561-rv5j1201	2484	19	to	to	IN
cord-022561-rv5j1201	2484	20	severe	severe	JJ
cord-022561-rv5j1201	2484	21	granulomatous	granulomatous	JJ
cord-022561-rv5j1201	2484	22	inflammation	inflammation	NN
cord-022561-rv5j1201	2484	23	with	with	IN
cord-022561-rv5j1201	2484	24	multinucleated	multinucleated	JJ
cord-022561-rv5j1201	2484	25	giant	giant	JJ
cord-022561-rv5j1201	2484	26	cells	cell	NNS
cord-022561-rv5j1201	2484	27	,	,	,
cord-022561-rv5j1201	2484	28	and	and	CC
cord-022561-rv5j1201	2484	29	intrahistiocytic	intrahistiocytic	JJ
cord-022561-rv5j1201	2484	30	sharply	sharply	RB
cord-022561-rv5j1201	2484	31	demarcated	demarcate	VBN
cord-022561-rv5j1201	2484	32	,	,	,
cord-022561-rv5j1201	2484	33	spherical	spherical	JJ
cord-022561-rv5j1201	2484	34	,	,	,
cord-022561-rv5j1201	2484	35	basophilic	basophilic	JJ
cord-022561-rv5j1201	2484	36	cytoplasmic	cytoplasmic	JJ
cord-022561-rv5j1201	2484	37	inclusion	inclusion	NN
cord-022561-rv5j1201	2484	38	bodies	body	NNS
cord-022561-rv5j1201	2484	39	.	.	.
cord-022561-rv5j1201	2485	1	Necrosis	necrosis	NN
cord-022561-rv5j1201	2485	2	of	of	IN
cord-022561-rv5j1201	2485	3	prominent	prominent	JJ
cord-022561-rv5j1201	2485	4	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	2485	5	follicles	follicle	NNS
cord-022561-rv5j1201	2485	6	(	(	-LRB-
cord-022561-rv5j1201	2485	7	necrotizing	necrotize	VBG
cord-022561-rv5j1201	2485	8	lymphadenitis	lymphadenitis	NN
cord-022561-rv5j1201	2485	9	)	)	-RRB-
cord-022561-rv5j1201	2485	10	is	be	VBZ
cord-022561-rv5j1201	2485	11	occasionally	occasionally	RB
cord-022561-rv5j1201	2485	12	observed	observe	VBN
cord-022561-rv5j1201	2485	13	,	,	,
cord-022561-rv5j1201	2485	14	and	and	CC
cord-022561-rv5j1201	2485	15	PCV2	PCV2	NNP
cord-022561-rv5j1201	2485	16	can	can	MD
cord-022561-rv5j1201	2485	17	be	be	VB
cord-022561-rv5j1201	2485	18	detected	detect	VBN
cord-022561-rv5j1201	2485	19	within	within	IN
cord-022561-rv5j1201	2485	20	the	the	DT
cord-022561-rv5j1201	2485	21	necrotic	necrotic	JJ
cord-022561-rv5j1201	2485	22	regions	region	NNS
cord-022561-rv5j1201	2485	23	.	.	.
cord-022561-rv5j1201	2486	1	The	the	DT
cord-022561-rv5j1201	2486	2	loss	loss	NN
cord-022561-rv5j1201	2486	3	of	of	IN
cord-022561-rv5j1201	2486	4	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	2486	5	may	may	MD
cord-022561-rv5j1201	2486	6	be	be	VB
cord-022561-rv5j1201	2486	7	due	due	JJ
cord-022561-rv5j1201	2486	8	to	to	IN
cord-022561-rv5j1201	2486	9	reduced	reduce	VBN
cord-022561-rv5j1201	2486	10	production	production	NN
cord-022561-rv5j1201	2486	11	in	in	IN
cord-022561-rv5j1201	2486	12	the	the	DT
cord-022561-rv5j1201	2486	13	bone	bone	NN
cord-022561-rv5j1201	2486	14	marrow	marrow	NN
cord-022561-rv5j1201	2486	15	,	,	,
cord-022561-rv5j1201	2486	16	decreased	decrease	VBD
cord-022561-rv5j1201	2486	17	proliferation	proliferation	NN
cord-022561-rv5j1201	2486	18	in	in	IN
cord-022561-rv5j1201	2486	19	the	the	DT
cord-022561-rv5j1201	2486	20	secondary	secondary	JJ
cord-022561-rv5j1201	2486	21	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	2486	22	organs	organ	NNS
cord-022561-rv5j1201	2486	23	,	,	,
cord-022561-rv5j1201	2486	24	or	or	CC
cord-022561-rv5j1201	2486	25	necrosis	necrosis	NN
cord-022561-rv5j1201	2486	26	of	of	IN
cord-022561-rv5j1201	2486	27	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	2486	28	.	.	.
cord-022561-rv5j1201	2487	1	Splenic	Splenic	NNP
cord-022561-rv5j1201	2487	2	abscesses	abscess	NNS
cord-022561-rv5j1201	2487	3	can	can	MD
cord-022561-rv5j1201	2487	4	be	be	VB
cord-022561-rv5j1201	2487	5	the	the	DT
cord-022561-rv5j1201	2487	6	result	result	NN
cord-022561-rv5j1201	2487	7	of	of	IN
cord-022561-rv5j1201	2487	8	bacteremia	bacteremia	NN
cord-022561-rv5j1201	2487	9	(	(	-LRB-
cord-022561-rv5j1201	2487	10	see	see	VB
cord-022561-rv5j1201	2487	11	Fig	Fig	NNP
cord-022561-rv5j1201	2487	12	.	.	.
cord-022561-rv5j1201	2487	13	13	13	CD
cord-022561-rv5j1201	2487	14	-69	-69	NNS
cord-022561-rv5j1201	2487	15	)	)	-RRB-
cord-022561-rv5j1201	2487	16	or	or	CC
cord-022561-rv5j1201	2487	17	direct	direct	JJ
cord-022561-rv5j1201	2487	18	penetration	penetration	NN
cord-022561-rv5j1201	2487	19	by	by	IN
cord-022561-rv5j1201	2487	20	a	a	DT
cord-022561-rv5j1201	2487	21	foreign	foreign	JJ
cord-022561-rv5j1201	2487	22	body	body	NN
cord-022561-rv5j1201	2487	23	from	from	IN
cord-022561-rv5j1201	2487	24	the	the	DT
cord-022561-rv5j1201	2487	25	reticulum	reticulum	NN
cord-022561-rv5j1201	2487	26	(	(	-LRB-
cord-022561-rv5j1201	2487	27	see	see	VB
cord-022561-rv5j1201	2487	28	Spleen	Spleen	NNP
cord-022561-rv5j1201	2487	29	and	and	CC
cord-022561-rv5j1201	2487	30	also	also	RB
cord-022561-rv5j1201	2487	31	Portals	Portals	NNPS
cord-022561-rv5j1201	2487	32	of	of	IN
cord-022561-rv5j1201	2487	33	Entry	Entry	NNP
cord-022561-rv5j1201	2487	34	/	/	SYM
cord-022561-rv5j1201	2487	35	Pathways	Pathways	NNPS
cord-022561-rv5j1201	2487	36	of	of	IN
cord-022561-rv5j1201	2487	37	Spread	Spread	NNP
cord-022561-rv5j1201	2487	38	)	)	-RRB-
cord-022561-rv5j1201	2487	39	.	.	.
cord-022561-rv5j1201	2488	1	C.	C.	NNP
cord-022561-rv5j1201	2488	2	pseudotuberculosis	pseudotuberculosis	NNP
cord-022561-rv5j1201	2488	3	is	be	VBZ
cord-022561-rv5j1201	2488	4	a	a	DT
cord-022561-rv5j1201	2488	5	Gram	Gram	NNP
cord-022561-rv5j1201	2488	6	-	-	HYPH
cord-022561-rv5j1201	2488	7	positive	positive	JJ
cord-022561-rv5j1201	2488	8	intracellular	intracellular	JJ
cord-022561-rv5j1201	2488	9	bacterium	bacterium	NN
cord-022561-rv5j1201	2488	10	that	that	WDT
cord-022561-rv5j1201	2488	11	causes	cause	VBZ
cord-022561-rv5j1201	2488	12	caseous	caseous	NNP
cord-022561-rv5j1201	2488	13	lymphadenitis	lymphadenitis	NNP
cord-022561-rv5j1201	2488	14	,	,	,
cord-022561-rv5j1201	2488	15	a	a	DT
cord-022561-rv5j1201	2488	16	chronic	chronic	JJ
cord-022561-rv5j1201	2488	17	suppurative	suppurative	JJ
cord-022561-rv5j1201	2488	18	disease	disease	NN
cord-022561-rv5j1201	2488	19	of	of	IN
cord-022561-rv5j1201	2488	20	sheep	sheep	NNS
cord-022561-rv5j1201	2488	21	and	and	CC
cord-022561-rv5j1201	2488	22	goats	goat	NNS
cord-022561-rv5j1201	2488	23	.	.	.
cord-022561-rv5j1201	2489	1	The	the	DT
cord-022561-rv5j1201	2489	2	bacterium	bacterium	NN
cord-022561-rv5j1201	2489	3	may	may	MD
cord-022561-rv5j1201	2489	4	enter	enter	VB
cord-022561-rv5j1201	2489	5	through	through	IN
cord-022561-rv5j1201	2489	6	skin	skin	NN
cord-022561-rv5j1201	2489	7	wounds	wound	NNS
cord-022561-rv5j1201	2489	8	(	(	-LRB-
cord-022561-rv5j1201	2489	9	e.g.	e.g.	RB
cord-022561-rv5j1201	2489	10	,	,	,
cord-022561-rv5j1201	2489	11	shearing	shearing	NN
cord-022561-rv5j1201	2489	12	cuts	cut	NNS
cord-022561-rv5j1201	2489	13	in	in	IN
cord-022561-rv5j1201	2489	14	sheep	sheep	NN
cord-022561-rv5j1201	2489	15	,	,	,
cord-022561-rv5j1201	2489	16	tagging	tagging	NN
cord-022561-rv5j1201	2489	17	,	,	,
cord-022561-rv5j1201	2489	18	tail	tail	NN
cord-022561-rv5j1201	2489	19	docking	docking	NN
cord-022561-rv5j1201	2489	20	,	,	,
cord-022561-rv5j1201	2489	21	or	or	CC
cord-022561-rv5j1201	2489	22	castration	castration	NN
cord-022561-rv5j1201	2489	23	)	)	-RRB-
cord-022561-rv5j1201	2489	24	,	,	,
cord-022561-rv5j1201	2489	25	drain	drain	VB
cord-022561-rv5j1201	2489	26	to	to	IN
cord-022561-rv5j1201	2489	27	the	the	DT
cord-022561-rv5j1201	2489	28	regional	regional	JJ
cord-022561-rv5j1201	2489	29	lymph	lymph	NN
cord-022561-rv5j1201	2489	30	node	node	NN
cord-022561-rv5j1201	2489	31	,	,	,
cord-022561-rv5j1201	2489	32	and	and	CC
cord-022561-rv5j1201	2489	33	then	then	RB
cord-022561-rv5j1201	2489	34	be	be	VB
cord-022561-rv5j1201	2489	35	disseminated	disseminate	VBN
cord-022561-rv5j1201	2489	36	in	in	IN
cord-022561-rv5j1201	2489	37	lymph	lymph	NN
cord-022561-rv5j1201	2489	38	and	and	CC
cord-022561-rv5j1201	2489	39	circulating	circulate	VBG
cord-022561-rv5j1201	2489	40	blood	blood	NN
cord-022561-rv5j1201	2489	41	to	to	IN
cord-022561-rv5j1201	2489	42	external	external	JJ
cord-022561-rv5j1201	2489	43	and	and	CC
cord-022561-rv5j1201	2489	44	internal	internal	JJ
cord-022561-rv5j1201	2489	45	lymph	lymph	NN
cord-022561-rv5j1201	2489	46	nodes	node	NNS
cord-022561-rv5j1201	2489	47	,	,	,
cord-022561-rv5j1201	2489	48	as	as	RB
cord-022561-rv5j1201	2489	49	well	well	RB
cord-022561-rv5j1201	2489	50	as	as	IN
cord-022561-rv5j1201	2489	51	other	other	JJ
cord-022561-rv5j1201	2489	52	internal	internal	JJ
cord-022561-rv5j1201	2489	53	organs	organ	NNS
cord-022561-rv5j1201	2489	54	,	,	,
cord-022561-rv5j1201	2489	55	including	include	VBG
cord-022561-rv5j1201	2489	56	lung	lung	NN
cord-022561-rv5j1201	2489	57	.	.	.
cord-022561-rv5j1201	2490	1	External	external	JJ
cord-022561-rv5j1201	2490	2	abscesses	abscess	NNS
cord-022561-rv5j1201	2490	3	are	be	VBP
cord-022561-rv5j1201	2490	4	most	most	RBS
cord-022561-rv5j1201	2490	5	often	often	RB
cord-022561-rv5j1201	2490	6	detected	detect	VBN
cord-022561-rv5j1201	2490	7	in	in	IN
cord-022561-rv5j1201	2490	8	the	the	DT
cord-022561-rv5j1201	2490	9	"	"	``
cord-022561-rv5j1201	2490	10	jaw	jaw	NN
cord-022561-rv5j1201	2490	11	and	and	CC
cord-022561-rv5j1201	2490	12	neck	neck	NN
cord-022561-rv5j1201	2490	13	"	"	''
cord-022561-rv5j1201	2490	14	region	region	NN
cord-022561-rv5j1201	2490	15	,	,	,
cord-022561-rv5j1201	2490	16	specifically	specifically	RB
cord-022561-rv5j1201	2490	17	in	in	IN
cord-022561-rv5j1201	2490	18	the	the	DT
cord-022561-rv5j1201	2490	19	mandibular	mandibular	JJ
cord-022561-rv5j1201	2490	20	and	and	CC
cord-022561-rv5j1201	2490	21	parotid	parotid	JJ
cord-022561-rv5j1201	2490	22	lymph	lymph	NN
cord-022561-rv5j1201	2490	23	nodes	node	NNS
cord-022561-rv5j1201	2490	24	.	.	.
cord-022561-rv5j1201	2491	1	On	on	IN
cord-022561-rv5j1201	2491	2	gross	gross	JJ
cord-022561-rv5j1201	2491	3	examination	examination	NN
cord-022561-rv5j1201	2491	4	the	the	DT
cord-022561-rv5j1201	2491	5	abscesses	abscess	NNS
cord-022561-rv5j1201	2491	6	are	be	VBP
cord-022561-rv5j1201	2491	7	encapsulated	encapsulate	VBN
cord-022561-rv5j1201	2491	8	and	and	CC
cord-022561-rv5j1201	2491	9	filled	fill	VBN
cord-022561-rv5j1201	2491	10	with	with	IN
cord-022561-rv5j1201	2491	11	greenish	greenish	JJ
cord-022561-rv5j1201	2491	12	semifluid	semifluid	JJ
cord-022561-rv5j1201	2491	13	pus	pus	NN
cord-022561-rv5j1201	2491	14	due	due	IN
cord-022561-rv5j1201	2491	15	to	to	IN
cord-022561-rv5j1201	2491	16	an	an	DT
cord-022561-rv5j1201	2491	17	infiltrate	infiltrate	NN
cord-022561-rv5j1201	2491	18	of	of	IN
cord-022561-rv5j1201	2491	19	eosinophils	eosinophil	NNS
cord-022561-rv5j1201	2491	20	(	(	-LRB-
cord-022561-rv5j1201	2491	21	see	see	VB
cord-022561-rv5j1201	2491	22	Fig	Fig	NNP
cord-022561-rv5j1201	2491	23	.	.	NNP
cord-022561-rv5j1201	2491	24	13	13	CD
cord-022561-rv5j1201	2491	25	-	-	SYM
cord-022561-rv5j1201	2491	26	79	79	CD
cord-022561-rv5j1201	2491	27	)	)	-RRB-
cord-022561-rv5j1201	2491	28	.	.	.
cord-022561-rv5j1201	2492	1	Over	over	IN
cord-022561-rv5j1201	2492	2	time	time	NN
cord-022561-rv5j1201	2492	3	the	the	DT
cord-022561-rv5j1201	2492	4	abscesses	abscess	NNS
cord-022561-rv5j1201	2492	5	lose	lose	VBP
cord-022561-rv5j1201	2492	6	the	the	DT
cord-022561-rv5j1201	2492	7	greenish	greenish	JJ
cord-022561-rv5j1201	2492	8	hue	hue	NN
cord-022561-rv5j1201	2492	9	,	,	,
cord-022561-rv5j1201	2492	10	and	and	CC
cord-022561-rv5j1201	2492	11	contents	content	NNS
cord-022561-rv5j1201	2492	12	become	become	VBP
cord-022561-rv5j1201	2492	13	inspissated	inspissated	JJ
cord-022561-rv5j1201	2492	14	to	to	TO
cord-022561-rv5j1201	2492	15	form	form	VB
cord-022561-rv5j1201	2492	16	the	the	DT
cord-022561-rv5j1201	2492	17	characteristic	characteristic	JJ
cord-022561-rv5j1201	2492	18	concentric	concentric	JJ
cord-022561-rv5j1201	2492	19	laminations	lamination	NNS
cord-022561-rv5j1201	2492	20	(	(	-LRB-
cord-022561-rv5j1201	2492	21	see	see	VB
cord-022561-rv5j1201	2492	22	Fig	Fig	NNP
cord-022561-rv5j1201	2492	23	.	.	.
cord-022561-rv5j1201	2493	1	13	13	CD
cord-022561-rv5j1201	2493	2	-80	-80	NNP
cord-022561-rv5j1201	2493	3	)	)	-RRB-
cord-022561-rv5j1201	2493	4	;	;	:
cord-022561-rv5j1201	2493	5	old	old	JJ
cord-022561-rv5j1201	2493	6	abscesses	abscess	NNS
cord-022561-rv5j1201	2493	7	may	may	MD
cord-022561-rv5j1201	2493	8	reach	reach	VB
cord-022561-rv5j1201	2493	9	a	a	DT
cord-022561-rv5j1201	2493	10	diameter	diameter	NN
cord-022561-rv5j1201	2493	11	of	of	IN
cord-022561-rv5j1201	2493	12	4	4	CD
cord-022561-rv5j1201	2493	13	to	to	TO
cord-022561-rv5j1201	2493	14	5	5	CD
cord-022561-rv5j1201	2493	15	cm	cm	NNS
cord-022561-rv5j1201	2493	16	.	.	.
cord-022561-rv5j1201	2494	1	Bovine	bovine	JJ
cord-022561-rv5j1201	2494	2	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2494	3	is	be	VBZ
cord-022561-rv5j1201	2494	4	broadly	broadly	RB
cord-022561-rv5j1201	2494	5	classified	classify	VBN
cord-022561-rv5j1201	2494	6	into	into	IN
cord-022561-rv5j1201	2494	7	enzootic	enzootic	JJ
cord-022561-rv5j1201	2494	8	and	and	CC
cord-022561-rv5j1201	2494	9	sporadic	sporadic	JJ
cord-022561-rv5j1201	2494	10	forms	form	NNS
cord-022561-rv5j1201	2494	11	.	.	.
cord-022561-rv5j1201	2495	1	The	the	DT
cord-022561-rv5j1201	2495	2	enzootic	enzootic	JJ
cord-022561-rv5j1201	2495	3	form	form	NN
cord-022561-rv5j1201	2495	4	,	,	,
cord-022561-rv5j1201	2495	5	called	call	VBN
cord-022561-rv5j1201	2495	6	enzootic	enzootic	JJ
cord-022561-rv5j1201	2495	7	bovine	bovine	NNP
cord-022561-rv5j1201	2495	8	leukosis	leukosis	NNP
cord-022561-rv5j1201	2495	9	(	(	-LRB-
cord-022561-rv5j1201	2495	10	EBL	EBL	NNP
cord-022561-rv5j1201	2495	11	)	)	-RRB-
cord-022561-rv5j1201	2495	12	,	,	,
cord-022561-rv5j1201	2495	13	is	be	VBZ
cord-022561-rv5j1201	2495	14	caused	cause	VBN
cord-022561-rv5j1201	2495	15	by	by	IN
cord-022561-rv5j1201	2495	16	BLV	BLV	NNP
cord-022561-rv5j1201	2495	17	,	,	,
cord-022561-rv5j1201	2495	18	a	a	DT
cord-022561-rv5j1201	2495	19	retrovirus	retrovirus	NN
cord-022561-rv5j1201	2495	20	common	common	JJ
cord-022561-rv5j1201	2495	21	in	in	IN
cord-022561-rv5j1201	2495	22	cattle	cattle	NNS
cord-022561-rv5j1201	2495	23	.	.	.
cord-022561-rv5j1201	2496	1	There	there	EX
cord-022561-rv5j1201	2496	2	is	be	VBZ
cord-022561-rv5j1201	2496	3	a	a	DT
cord-022561-rv5j1201	2496	4	higher	high	JJR
cord-022561-rv5j1201	2496	5	prevalence	prevalence	NN
cord-022561-rv5j1201	2496	6	in	in	IN
cord-022561-rv5j1201	2496	7	dairy	dairy	NN
cord-022561-rv5j1201	2496	8	cattle	cattle	NNS
cord-022561-rv5j1201	2496	9	compared	compare	VBN
cord-022561-rv5j1201	2496	10	to	to	IN
cord-022561-rv5j1201	2496	11	beef	beef	NN
cord-022561-rv5j1201	2496	12	breeds	breed	NNS
cord-022561-rv5j1201	2496	13	.	.	.
cord-022561-rv5j1201	2497	1	BLV	BLV	NNP
cord-022561-rv5j1201	2497	2	is	be	VBZ
cord-022561-rv5j1201	2497	3	transmitted	transmit	VBN
cord-022561-rv5j1201	2497	4	horizontally	horizontally	RB
cord-022561-rv5j1201	2497	5	(	(	-LRB-
cord-022561-rv5j1201	2497	6	e.g.	e.g.	RB
cord-022561-rv5j1201	2497	7	,	,	,
cord-022561-rv5j1201	2497	8	blood	blood	NN
cord-022561-rv5j1201	2497	9	,	,	,
cord-022561-rv5j1201	2497	10	milk	milk	NN
cord-022561-rv5j1201	2497	11	/	/	SYM
cord-022561-rv5j1201	2497	12	colostrum	colostrum	NN
cord-022561-rv5j1201	2497	13	,	,	,
cord-022561-rv5j1201	2497	14	saliva	saliva	NN
cord-022561-rv5j1201	2497	15	)	)	-RRB-
cord-022561-rv5j1201	2497	16	or	or	CC
cord-022561-rv5j1201	2497	17	iatrogenically	iatrogenically	RB
cord-022561-rv5j1201	2497	18	(	(	-LRB-
cord-022561-rv5j1201	2497	19	e.g.	e.g.	RB
cord-022561-rv5j1201	2497	20	,	,	,
cord-022561-rv5j1201	2497	21	rectal	rectal	JJ
cord-022561-rv5j1201	2497	22	sleeves	sleeve	NNS
cord-022561-rv5j1201	2497	23	,	,	,
cord-022561-rv5j1201	2497	24	instruments	instrument	NNS
cord-022561-rv5j1201	2497	25	/	/	SYM
cord-022561-rv5j1201	2497	26	equipment	equipment	NN
cord-022561-rv5j1201	2497	27	)	)	-RRB-
cord-022561-rv5j1201	2497	28	.	.	.
cord-022561-rv5j1201	2498	1	Following	follow	VBG
cord-022561-rv5j1201	2498	2	infection	infection	NN
cord-022561-rv5j1201	2498	3	,	,	,
cord-022561-rv5j1201	2498	4	BLV	BLV	NNP
cord-022561-rv5j1201	2498	5	invades	invade	VBZ
cord-022561-rv5j1201	2498	6	and	and	CC
cord-022561-rv5j1201	2498	7	integrates	integrate	VBZ
cord-022561-rv5j1201	2498	8	into	into	IN
cord-022561-rv5j1201	2498	9	the	the	DT
cord-022561-rv5j1201	2498	10	genome	genome	NN
cord-022561-rv5j1201	2498	11	of	of	IN
cord-022561-rv5j1201	2498	12	infected	infect	VBN
cord-022561-rv5j1201	2498	13	B	b	NN
cord-022561-rv5j1201	2498	14	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	2498	15	,	,	,
cord-022561-rv5j1201	2498	16	resulting	result	VBG
cord-022561-rv5j1201	2498	17	in	in	IN
cord-022561-rv5j1201	2498	18	a	a	DT
cord-022561-rv5j1201	2498	19	polyclonal	polyclonal	JJ
cord-022561-rv5j1201	2498	20	B	b	NN
cord-022561-rv5j1201	2498	21	lymphocyte	lymphocyte	NN
cord-022561-rv5j1201	2498	22	lymphocytosis	lymphocytosis	NN
cord-022561-rv5j1201	2498	23	in	in	IN
cord-022561-rv5j1201	2498	24	approximately	approximately	RB
cord-022561-rv5j1201	2498	25	30	30	CD
cord-022561-rv5j1201	2498	26	%	%	NN
cord-022561-rv5j1201	2498	27	of	of	IN
cord-022561-rv5j1201	2498	28	cattle	cattle	NNS
cord-022561-rv5j1201	2498	29	.	.	.
cord-022561-rv5j1201	2499	1	In	in	IN
cord-022561-rv5j1201	2499	2	approximately	approximately	RB
cord-022561-rv5j1201	2499	3	1	1	CD
cord-022561-rv5j1201	2499	4	%	%	NN
cord-022561-rv5j1201	2499	5	to	to	TO
cord-022561-rv5j1201	2499	6	5	5	CD
cord-022561-rv5j1201	2499	7	%	%	NN
cord-022561-rv5j1201	2499	8	of	of	IN
cord-022561-rv5j1201	2499	9	BLV	BLV	NNP
cord-022561-rv5j1201	2499	10	-	-	HYPH
cord-022561-rv5j1201	2499	11	infected	infect	VBN
cord-022561-rv5j1201	2499	12	cattle	cattle	NNS
cord-022561-rv5j1201	2499	13	,	,	,
cord-022561-rv5j1201	2499	14	a	a	DT
cord-022561-rv5j1201	2499	15	single	single	JJ
cord-022561-rv5j1201	2499	16	clone	clone	NN
cord-022561-rv5j1201	2499	17	will	will	MD
cord-022561-rv5j1201	2499	18	emerge	emerge	VB
cord-022561-rv5j1201	2499	19	,	,	,
cord-022561-rv5j1201	2499	20	leading	lead	VBG
cord-022561-rv5j1201	2499	21	to	to	IN
cord-022561-rv5j1201	2499	22	the	the	DT
cord-022561-rv5j1201	2499	23	development	development	NN
cord-022561-rv5j1201	2499	24	of	of	IN
cord-022561-rv5j1201	2499	25	B	B	NNP
cord-022561-rv5j1201	2499	26	lymphocyte	lymphocyte	NN
cord-022561-rv5j1201	2499	27	leukemia	leukemia	NN
cord-022561-rv5j1201	2499	28	/	/	SYM
cord-022561-rv5j1201	2499	29	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2499	30	.	.	.
cord-022561-rv5j1201	2500	1	The	the	DT
cord-022561-rv5j1201	2500	2	average	average	JJ
cord-022561-rv5j1201	2500	3	incubation	incubation	NN
cord-022561-rv5j1201	2500	4	period	period	NN
cord-022561-rv5j1201	2500	5	between	between	IN
cord-022561-rv5j1201	2500	6	infection	infection	NN
cord-022561-rv5j1201	2500	7	and	and	CC
cord-022561-rv5j1201	2500	8	development	development	NN
cord-022561-rv5j1201	2500	9	of	of	IN
cord-022561-rv5j1201	2500	10	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2500	11	is	be	VBZ
cord-022561-rv5j1201	2500	12	7	7	CD
cord-022561-rv5j1201	2500	13	to	to	TO
cord-022561-rv5j1201	2500	14	8	8	CD
cord-022561-rv5j1201	2500	15	years	year	NNS
cord-022561-rv5j1201	2500	16	,	,	,
cord-022561-rv5j1201	2500	17	and	and	CC
cord-022561-rv5j1201	2500	18	this	this	DT
cord-022561-rv5j1201	2500	19	low	low	JJ
cord-022561-rv5j1201	2500	20	conversion	conversion	NN
cord-022561-rv5j1201	2500	21	rate	rate	NN
cord-022561-rv5j1201	2500	22	suggests	suggest	VBZ
cord-022561-rv5j1201	2500	23	that	that	IN
cord-022561-rv5j1201	2500	24	the	the	DT
cord-022561-rv5j1201	2500	25	latency	latency	NN
cord-022561-rv5j1201	2500	26	period	period	NN
cord-022561-rv5j1201	2500	27	may	may	MD
cord-022561-rv5j1201	2500	28	be	be	VB
cord-022561-rv5j1201	2500	29	longer	long	JJR
cord-022561-rv5j1201	2500	30	than	than	IN
cord-022561-rv5j1201	2500	31	the	the	DT
cord-022561-rv5j1201	2500	32	life	life	NN
cord-022561-rv5j1201	2500	33	span	span	NN
cord-022561-rv5j1201	2500	34	of	of	IN
cord-022561-rv5j1201	2500	35	most	most	JJS
cord-022561-rv5j1201	2500	36	animals	animal	NNS
cord-022561-rv5j1201	2500	37	(	(	-LRB-
cord-022561-rv5j1201	2500	38	dairy	dairy	NN
cord-022561-rv5j1201	2500	39	cattle	cattle	NNS
cord-022561-rv5j1201	2500	40	seldom	seldom	RB
cord-022561-rv5j1201	2500	41	live	live	VBP
cord-022561-rv5j1201	2500	42	to	to	IN
cord-022561-rv5j1201	2500	43	the	the	DT
cord-022561-rv5j1201	2500	44	7-to	7-to	CD
cord-022561-rv5j1201	2500	45	8-year	8-year	JJ
cord-022561-rv5j1201	2500	46	peak	peak	NN
cord-022561-rv5j1201	2500	47	incidence	incidence	NN
cord-022561-rv5j1201	2500	48	of	of	IN
cord-022561-rv5j1201	2500	49	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2500	50	occurrence	occurrence	NN
cord-022561-rv5j1201	2500	51	)	)	-RRB-
cord-022561-rv5j1201	2500	52	.	.	.
cord-022561-rv5j1201	2501	1	Other	other	JJ
cord-022561-rv5j1201	2501	2	contributing	contribute	VBG
cord-022561-rv5j1201	2501	3	variables	variable	NNS
cord-022561-rv5j1201	2501	4	,	,	,
cord-022561-rv5j1201	2501	5	such	such	JJ
cord-022561-rv5j1201	2501	6	as	as	IN
cord-022561-rv5j1201	2501	7	genetic	genetic	JJ
cord-022561-rv5j1201	2501	8	background	background	NN
cord-022561-rv5j1201	2501	9	,	,	,
cord-022561-rv5j1201	2501	10	coinfections	coinfection	NNS
cord-022561-rv5j1201	2501	11	,	,	,
cord-022561-rv5j1201	2501	12	and	and	CC
cord-022561-rv5j1201	2501	13	environmental	environmental	JJ
cord-022561-rv5j1201	2501	14	factors	factor	NNS
cord-022561-rv5j1201	2501	15	,	,	,
cord-022561-rv5j1201	2501	16	may	may	MD
cord-022561-rv5j1201	2501	17	also	also	RB
cord-022561-rv5j1201	2501	18	play	play	VB
cord-022561-rv5j1201	2501	19	a	a	DT
cord-022561-rv5j1201	2501	20	role	role	NN
cord-022561-rv5j1201	2501	21	in	in	IN
cord-022561-rv5j1201	2501	22	lymphomagenesis	lymphomagenesis	NNP
cord-022561-rv5j1201	2501	23	.	.	.
cord-022561-rv5j1201	2502	1	The	the	DT
cord-022561-rv5j1201	2502	2	exact	exact	JJ
cord-022561-rv5j1201	2502	3	mechanism	mechanism	NN
cord-022561-rv5j1201	2502	4	of	of	IN
cord-022561-rv5j1201	2502	5	BLV	BLV	NNP
cord-022561-rv5j1201	2502	6	-	-	HYPH
cord-022561-rv5j1201	2502	7	induced	induce	VBN
cord-022561-rv5j1201	2502	8	tumorigenesis	tumorigenesis	NN
cord-022561-rv5j1201	2502	9	is	be	VBZ
cord-022561-rv5j1201	2502	10	poorly	poorly	RB
cord-022561-rv5j1201	2502	11	understood	understand	VBN
cord-022561-rv5j1201	2502	12	.	.	.
cord-022561-rv5j1201	2503	1	Recently	recently	RB
cord-022561-rv5j1201	2503	2	BLV	BLV	NNP
cord-022561-rv5j1201	2503	3	microRNAs	microRNAs	NNP
cord-022561-rv5j1201	2503	4	(	(	-LRB-
cord-022561-rv5j1201	2503	5	miRNAs	miRNAs	NNP
cord-022561-rv5j1201	2503	6	)	)	-RRB-
cord-022561-rv5j1201	2503	7	were	be	VBD
cord-022561-rv5j1201	2503	8	identified	identify	VBN
cord-022561-rv5j1201	2503	9	in	in	IN
cord-022561-rv5j1201	2503	10	preleukemic	preleukemic	JJ
cord-022561-rv5j1201	2503	11	and	and	CC
cord-022561-rv5j1201	2503	12	malignant	malignant	JJ
cord-022561-rv5j1201	2503	13	B	b	NN
cord-022561-rv5j1201	2503	14	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	2503	15	,	,	,
cord-022561-rv5j1201	2503	16	which	which	WDT
cord-022561-rv5j1201	2503	17	showed	show	VBD
cord-022561-rv5j1201	2503	18	repression	repression	NN
cord-022561-rv5j1201	2503	19	of	of	IN
cord-022561-rv5j1201	2503	20	structural	structural	JJ
cord-022561-rv5j1201	2503	21	and	and	CC
cord-022561-rv5j1201	2503	22	regulatory	regulatory	JJ
cord-022561-rv5j1201	2503	23	gene	gene	NN
cord-022561-rv5j1201	2503	24	expression	expression	NN
cord-022561-rv5j1201	2503	25	.	.	.
cord-022561-rv5j1201	2504	1	These	these	DT
cord-022561-rv5j1201	2504	2	findings	finding	NNS
cord-022561-rv5j1201	2504	3	suggested	suggest	VBD
cord-022561-rv5j1201	2504	4	that	that	IN
cord-022561-rv5j1201	2504	5	miRNAs	miRNAs	NNP
cord-022561-rv5j1201	2504	6	may	may	MD
cord-022561-rv5j1201	2504	7	play	play	VB
cord-022561-rv5j1201	2504	8	a	a	DT
cord-022561-rv5j1201	2504	9	key	key	JJ
cord-022561-rv5j1201	2504	10	role	role	NN
cord-022561-rv5j1201	2504	11	in	in	IN
cord-022561-rv5j1201	2504	12	tumor	tumor	NN
cord-022561-rv5j1201	2504	13	onset	onset	NN
cord-022561-rv5j1201	2504	14	and	and	CC
cord-022561-rv5j1201	2504	15	progression	progression	NN
cord-022561-rv5j1201	2504	16	.	.	.
cord-022561-rv5j1201	2505	1	Grossly	grossly	RB
cord-022561-rv5j1201	2505	2	,	,	,
cord-022561-rv5j1201	2505	3	multiple	multiple	JJ
cord-022561-rv5j1201	2505	4	tissues	tissue	NNS
cord-022561-rv5j1201	2505	5	may	may	MD
cord-022561-rv5j1201	2505	6	be	be	VB
cord-022561-rv5j1201	2505	7	affected	affect	VBN
cord-022561-rv5j1201	2505	8	in	in	IN
cord-022561-rv5j1201	2505	9	cattle	cattle	NNS
cord-022561-rv5j1201	2505	10	that	that	WDT
cord-022561-rv5j1201	2505	11	develop	develop	VBP
cord-022561-rv5j1201	2505	12	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2505	13	,	,	,
cord-022561-rv5j1201	2505	14	including	include	VBG
cord-022561-rv5j1201	2505	15	peripheral	peripheral	JJ
cord-022561-rv5j1201	2505	16	lymph	lymph	NN
cord-022561-rv5j1201	2505	17	nodes	node	NNS
cord-022561-rv5j1201	2505	18	(	(	-LRB-
cord-022561-rv5j1201	2505	19	cephalic	cephalic	JJ
cord-022561-rv5j1201	2505	20	,	,	,
cord-022561-rv5j1201	2505	21	cervical	cervical	JJ
cord-022561-rv5j1201	2505	22	,	,	,
cord-022561-rv5j1201	2505	23	sublumbar	sublumbar	NN
cord-022561-rv5j1201	2505	24	)	)	-RRB-
cord-022561-rv5j1201	2505	25	(	(	-LRB-
cord-022561-rv5j1201	2505	26	Fig	Fig	NNP
cord-022561-rv5j1201	2505	27	.	.	.
cord-022561-rv5j1201	2505	28	13	13	CD
cord-022561-rv5j1201	2505	29	-	-	SYM
cord-022561-rv5j1201	2505	30	87	87	CD
cord-022561-rv5j1201	2505	31	)	)	-RRB-
cord-022561-rv5j1201	2505	32	,	,	,
cord-022561-rv5j1201	2505	33	abdominal	abdominal	JJ
cord-022561-rv5j1201	2505	34	lymph	lymph	NN
cord-022561-rv5j1201	2505	35	nodes	node	NNS
cord-022561-rv5j1201	2505	36	,	,	,
cord-022561-rv5j1201	2505	37	retrobulbar	retrobulbar	NN
cord-022561-rv5j1201	2505	38	region	region	NN
cord-022561-rv5j1201	2505	39	,	,	,
cord-022561-rv5j1201	2505	40	abomasum	abomasum	NN
cord-022561-rv5j1201	2505	41	,	,	,
cord-022561-rv5j1201	2505	42	liver	liver	NN
cord-022561-rv5j1201	2505	43	,	,	,
cord-022561-rv5j1201	2505	44	spleen	spleen	NN
cord-022561-rv5j1201	2505	45	,	,	,
cord-022561-rv5j1201	2505	46	heart	heart	NN
cord-022561-rv5j1201	2505	47	,	,	,
cord-022561-rv5j1201	2505	48	urogenital	urogenital	JJ
cord-022561-rv5j1201	2505	49	tract	tract	NN
cord-022561-rv5j1201	2505	50	,	,	,
cord-022561-rv5j1201	2505	51	bone	bone	NN
cord-022561-rv5j1201	2505	52	marrow	marrow	NN
cord-022561-rv5j1201	2505	53	,	,	,
cord-022561-rv5j1201	2505	54	vertebral	vertebral	JJ
cord-022561-rv5j1201	2505	55	canal	canal	NN
cord-022561-rv5j1201	2505	56	(	(	-LRB-
cord-022561-rv5j1201	2505	57	Fig	Fig	NNP
cord-022561-rv5j1201	2505	58	.	.	.
cord-022561-rv5j1201	2505	59	13	13	CD
cord-022561-rv5j1201	2505	60	-	-	SYM
cord-022561-rv5j1201	2505	61	88	88	CD
cord-022561-rv5j1201	2505	62	)	)	-RRB-
cord-022561-rv5j1201	2505	63	,	,	,
cord-022561-rv5j1201	2505	64	and	and	CC
cord-022561-rv5j1201	2505	65	spinal	spinal	JJ
cord-022561-rv5j1201	2505	66	cord	cord	NN
cord-022561-rv5j1201	2505	67	.	.	.
cord-022561-rv5j1201	2506	1	One	one	CD
cord-022561-rv5j1201	2506	2	study	study	NN
cord-022561-rv5j1201	2506	3	indicates	indicate	VBZ
cord-022561-rv5j1201	2506	4	most	most	JJS
cord-022561-rv5j1201	2506	5	of	of	IN
cord-022561-rv5j1201	2506	6	these	these	DT
cord-022561-rv5j1201	2506	7	high	high	JJ
cord-022561-rv5j1201	2506	8	-	-	HYPH
cord-022561-rv5j1201	2506	9	grade	grade	NN
cord-022561-rv5j1201	2506	10	lymphomas	lymphoma	NNS
cord-022561-rv5j1201	2506	11	are	be	VBP
cord-022561-rv5j1201	2506	12	diffuse	diffuse	JJ
cord-022561-rv5j1201	2506	13	large	large	JJ
cord-022561-rv5j1201	2506	14	cell	cell	NN
cord-022561-rv5j1201	2506	15	lymphomas	lymphoma	NNS
cord-022561-rv5j1201	2506	16	(	(	-LRB-
cord-022561-rv5j1201	2506	17	66	66	CD
cord-022561-rv5j1201	2506	18	%	%	NN
cord-022561-rv5j1201	2506	19	)	)	-RRB-
cord-022561-rv5j1201	2506	20	,	,	,
cord-022561-rv5j1201	2506	21	and	and	CC
cord-022561-rv5j1201	2506	22	approximately	approximately	RB
cord-022561-rv5j1201	2506	23	20	20	CD
cord-022561-rv5j1201	2506	24	%	%	NN
cord-022561-rv5j1201	2506	25	are	be	VBP
cord-022561-rv5j1201	2506	26	intermediate	intermediate	JJ
cord-022561-rv5j1201	2506	27	cell	cell	NN
cord-022561-rv5j1201	2506	28	lymphomas	lymphoma	NNS
cord-022561-rv5j1201	2506	29	(	(	-LRB-
cord-022561-rv5j1201	2506	30	Burkitt	Burkitt	NNP
cord-022561-rv5j1201	2506	31	-	-	HYPH
cord-022561-rv5j1201	2506	32	like	like	JJ
cord-022561-rv5j1201	2506	33	and	and	CC
cord-022561-rv5j1201	2506	34	lymphoblastic	lymphoblastic	JJ
cord-022561-rv5j1201	2506	35	lymphomas	lymphoma	NNS
cord-022561-rv5j1201	2506	36	)	)	-RRB-
cord-022561-rv5j1201	2506	37	.	.	.
cord-022561-rv5j1201	2507	1	The	the	DT
cord-022561-rv5j1201	2507	2	sporadic	sporadic	JJ
cord-022561-rv5j1201	2507	3	form	form	NN
cord-022561-rv5j1201	2507	4	of	of	IN
cord-022561-rv5j1201	2507	5	bovine	bovine	JJ
cord-022561-rv5j1201	2507	6	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2507	7	is	be	VBZ
cord-022561-rv5j1201	2507	8	most	most	RBS
cord-022561-rv5j1201	2507	9	often	often	RB
cord-022561-rv5j1201	2507	10	of	of	IN
cord-022561-rv5j1201	2507	11	T	T	NNP
cord-022561-rv5j1201	2507	12	lymphocyte	lymphocyte	NN
cord-022561-rv5j1201	2507	13	immunophenotype	immunophenotype	NN
cord-022561-rv5j1201	2507	14	and	and	CC
cord-022561-rv5j1201	2507	15	has	have	VBZ
cord-022561-rv5j1201	2507	16	three	three	CD
cord-022561-rv5j1201	2507	17	subcategories	subcategorie	NNS
cord-022561-rv5j1201	2507	18	:	:	:
cord-022561-rv5j1201	2507	19	cutaneous	cutaneous	JJ
cord-022561-rv5j1201	2507	20	,	,	,
cord-022561-rv5j1201	2507	21	calf	calf	NN
cord-022561-rv5j1201	2507	22	,	,	,
cord-022561-rv5j1201	2507	23	and	and	CC
cord-022561-rv5j1201	2507	24	thymic	thymic	JJ
cord-022561-rv5j1201	2507	25	.	.	.
cord-022561-rv5j1201	2508	1	There	there	EX
cord-022561-rv5j1201	2508	2	is	be	VBZ
cord-022561-rv5j1201	2508	3	no	no	DT
cord-022561-rv5j1201	2508	4	known	know	VBN
cord-022561-rv5j1201	2508	5	viral	viral	JJ
cord-022561-rv5j1201	2508	6	cause	cause	NN
cord-022561-rv5j1201	2508	7	for	for	IN
cord-022561-rv5j1201	2508	8	the	the	DT
cord-022561-rv5j1201	2508	9	sporadic	sporadic	JJ
cord-022561-rv5j1201	2508	10	form	form	NN
cord-022561-rv5j1201	2508	11	,	,	,
cord-022561-rv5j1201	2508	12	and	and	CC
cord-022561-rv5j1201	2508	13	each	each	DT
cord-022561-rv5j1201	2508	14	subcategory	subcategory	NN
cord-022561-rv5j1201	2508	15	has	have	VBZ
cord-022561-rv5j1201	2508	16	a	a	DT
cord-022561-rv5j1201	2508	17	much	much	RB
cord-022561-rv5j1201	2508	18	smaller	small	JJR
cord-022561-rv5j1201	2508	19	prevalence	prevalence	NN
cord-022561-rv5j1201	2508	20	compared	compare	VBN
cord-022561-rv5j1201	2508	21	to	to	IN
cord-022561-rv5j1201	2508	22	the	the	DT
cord-022561-rv5j1201	2508	23	enzootic	enzootic	JJ
cord-022561-rv5j1201	2508	24	form	form	NN
cord-022561-rv5j1201	2508	25	.	.	.
cord-022561-rv5j1201	2509	1	Of	of	IN
cord-022561-rv5j1201	2509	2	the	the	DT
cord-022561-rv5j1201	2509	3	three	three	CD
cord-022561-rv5j1201	2509	4	sporadic	sporadic	JJ
cord-022561-rv5j1201	2509	5	forms	form	NNS
cord-022561-rv5j1201	2509	6	,	,	,
cord-022561-rv5j1201	2509	7	the	the	DT
cord-022561-rv5j1201	2509	8	cutaneous	cutaneous	JJ
cord-022561-rv5j1201	2509	9	form	form	NN
cord-022561-rv5j1201	2509	10	seems	seem	VBZ
cord-022561-rv5j1201	2509	11	to	to	TO
cord-022561-rv5j1201	2509	12	be	be	VB
cord-022561-rv5j1201	2509	13	the	the	DT
cord-022561-rv5j1201	2509	14	most	most	RBS
cord-022561-rv5j1201	2509	15	common	common	JJ
cord-022561-rv5j1201	2509	16	and	and	CC
cord-022561-rv5j1201	2509	17	manifests	manifest	VBZ
cord-022561-rv5j1201	2509	18	itself	-PRON-	PRP
cord-022561-rv5j1201	2509	19	as	as	IN
cord-022561-rv5j1201	2509	20	multiple	multiple	JJ
cord-022561-rv5j1201	2509	21	skin	skin	NN
cord-022561-rv5j1201	2509	22	nodules	nodule	NNS
cord-022561-rv5j1201	2509	23	in	in	IN
cord-022561-rv5j1201	2509	24	1-to	1-to	CD
cord-022561-rv5j1201	2509	25	3-year	3-year	JJ
cord-022561-rv5j1201	2509	26	-	-	HYPH
cord-022561-rv5j1201	2509	27	old	old	JJ
cord-022561-rv5j1201	2509	28	cattle	cattle	NNS
cord-022561-rv5j1201	2509	29	.	.	.
cord-022561-rv5j1201	2510	1	The	the	DT
cord-022561-rv5j1201	2510	2	calf	calf	NN
cord-022561-rv5j1201	2510	3	form	form	NN
cord-022561-rv5j1201	2510	4	presents	present	VBZ
cord-022561-rv5j1201	2510	5	as	as	IN
cord-022561-rv5j1201	2510	6	generalized	generalize	VBN
cord-022561-rv5j1201	2510	7	lymphadenopathy	lymphadenopathy	NN
cord-022561-rv5j1201	2510	8	with	with	IN
cord-022561-rv5j1201	2510	9	weight	weight	NN
cord-022561-rv5j1201	2510	10	loss	loss	NN
cord-022561-rv5j1201	2510	11	,	,	,
cord-022561-rv5j1201	2510	12	lethargy	lethargy	NN
cord-022561-rv5j1201	2510	13	,	,	,
cord-022561-rv5j1201	2510	14	and	and	CC
cord-022561-rv5j1201	2510	15	weakness	weakness	NN
cord-022561-rv5j1201	2510	16	in	in	IN
cord-022561-rv5j1201	2510	17	calves	calf	NNS
cord-022561-rv5j1201	2510	18	less	less	JJR
cord-022561-rv5j1201	2510	19	than	than	IN
cord-022561-rv5j1201	2510	20	6	6	CD
cord-022561-rv5j1201	2510	21	months	month	NNS
cord-022561-rv5j1201	2510	22	old	old	JJ
cord-022561-rv5j1201	2510	23	.	.	.
cord-022561-rv5j1201	2511	1	The	the	DT
cord-022561-rv5j1201	2511	2	thymic	thymic	JJ
cord-022561-rv5j1201	2511	3	form	form	NN
cord-022561-rv5j1201	2511	4	is	be	VBZ
cord-022561-rv5j1201	2511	5	reportedly	reportedly	RB
cord-022561-rv5j1201	2511	6	more	more	RBR
cord-022561-rv5j1201	2511	7	common	common	JJ
cord-022561-rv5j1201	2511	8	in	in	IN
cord-022561-rv5j1201	2511	9	beef	beef	NN
cord-022561-rv5j1201	2511	10	cattle	cattle	NNS
cord-022561-rv5j1201	2511	11	,	,	,
cord-022561-rv5j1201	2511	12	6	6	CD
cord-022561-rv5j1201	2511	13	to	to	TO
cord-022561-rv5j1201	2511	14	24	24	CD
cord-022561-rv5j1201	2511	15	months	month	NNS
cord-022561-rv5j1201	2511	16	of	of	IN
cord-022561-rv5j1201	2511	17	age	age	NN
cord-022561-rv5j1201	2511	18	.	.	.
cord-022561-rv5j1201	2512	1	Lymphoma	Lymphoma	NNP
cord-022561-rv5j1201	2512	2	is	be	VBZ
cord-022561-rv5j1201	2512	3	the	the	DT
cord-022561-rv5j1201	2512	4	most	most	RBS
cord-022561-rv5j1201	2512	5	frequently	frequently	RB
cord-022561-rv5j1201	2512	6	reported	report	VBN
cord-022561-rv5j1201	2512	7	cancer	cancer	NN
cord-022561-rv5j1201	2512	8	of	of	IN
cord-022561-rv5j1201	2512	9	pigs	pig	NNS
cord-022561-rv5j1201	2512	10	based	base	VBN
cord-022561-rv5j1201	2512	11	on	on	IN
cord-022561-rv5j1201	2512	12	abattoir	abattoir	NN
cord-022561-rv5j1201	2512	13	surveys	survey	NNS
cord-022561-rv5j1201	2512	14	.	.	.
cord-022561-rv5j1201	2513	1	Affected	affected	JJ
cord-022561-rv5j1201	2513	2	pigs	pig	NNS
cord-022561-rv5j1201	2513	3	are	be	VBP
cord-022561-rv5j1201	2513	4	typically	typically	RB
cord-022561-rv5j1201	2513	5	less	less	JJR
cord-022561-rv5j1201	2513	6	than	than	IN
cord-022561-rv5j1201	2513	7	1	1	CD
cord-022561-rv5j1201	2513	8	year	year	NN
cord-022561-rv5j1201	2513	9	of	of	IN
cord-022561-rv5j1201	2513	10	age	age	NN
cord-022561-rv5j1201	2513	11	,	,	,
cord-022561-rv5j1201	2513	12	and	and	CC
cord-022561-rv5j1201	2513	13	there	there	EX
cord-022561-rv5j1201	2513	14	is	be	VBZ
cord-022561-rv5j1201	2513	15	no	no	DT
cord-022561-rv5j1201	2513	16	reported	report	VBN
cord-022561-rv5j1201	2513	17	breed	breed	JJ
cord-022561-rv5j1201	2513	18	predisposition	predisposition	NN
cord-022561-rv5j1201	2513	19	,	,	,
cord-022561-rv5j1201	2513	20	although	although	IN
cord-022561-rv5j1201	2513	21	a	a	DT
cord-022561-rv5j1201	2513	22	hereditary	hereditary	JJ
cord-022561-rv5j1201	2513	23	basis	basis	NN
cord-022561-rv5j1201	2513	24	is	be	VBZ
cord-022561-rv5j1201	2513	25	suspected	suspect	VBN
cord-022561-rv5j1201	2513	26	in	in	IN
cord-022561-rv5j1201	2513	27	cases	case	NNS
cord-022561-rv5j1201	2513	28	arising	arise	VBG
cord-022561-rv5j1201	2513	29	in	in	IN
cord-022561-rv5j1201	2513	30	inbred	inbred	JJ
cord-022561-rv5j1201	2513	31	herds	herd	NNS
cord-022561-rv5j1201	2513	32	.	.	.
cord-022561-rv5j1201	2514	1	The	the	DT
cord-022561-rv5j1201	2514	2	two	two	CD
cord-022561-rv5j1201	2514	3	main	main	JJ
cord-022561-rv5j1201	2514	4	forms	form	NNS
cord-022561-rv5j1201	2514	5	of	of	IN
cord-022561-rv5j1201	2514	6	porcine	porcine	JJ
cord-022561-rv5j1201	2514	7	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2514	8	are	be	VBP
cord-022561-rv5j1201	2514	9	thymic	thymic	JJ
cord-022561-rv5j1201	2514	10	/	/	SYM
cord-022561-rv5j1201	2514	11	mediastinal	mediastinal	JJ
cord-022561-rv5j1201	2514	12	and	and	CC
cord-022561-rv5j1201	2514	13	multicentric	multicentric	NNP
cord-022561-rv5j1201	2514	14	;	;	:
cord-022561-rv5j1201	2514	15	the	the	DT
cord-022561-rv5j1201	2514	16	latter	latter	JJ
cord-022561-rv5j1201	2514	17	is	be	VBZ
cord-022561-rv5j1201	2514	18	more	more	RBR
cord-022561-rv5j1201	2514	19	common	common	JJ
cord-022561-rv5j1201	2514	20	.	.	.
cord-022561-rv5j1201	2515	1	Spleen	spleen	NN
cord-022561-rv5j1201	2515	2	,	,	,
cord-022561-rv5j1201	2515	3	liver	liver	NN
cord-022561-rv5j1201	2515	4	,	,	,
cord-022561-rv5j1201	2515	5	kidney	kidney	NN
cord-022561-rv5j1201	2515	6	,	,	,
cord-022561-rv5j1201	2515	7	bone	bone	NN
cord-022561-rv5j1201	2515	8	marrow	marrow	NN
cord-022561-rv5j1201	2515	9	,	,	,
cord-022561-rv5j1201	2515	10	and	and	CC
cord-022561-rv5j1201	2515	11	lymph	lymph	NN
cord-022561-rv5j1201	2515	12	nodes	node	NNS
cord-022561-rv5j1201	2515	13	are	be	VBP
cord-022561-rv5j1201	2515	14	affected	affect	VBN
cord-022561-rv5j1201	2515	15	in	in	IN
cord-022561-rv5j1201	2515	16	the	the	DT
cord-022561-rv5j1201	2515	17	multicentric	multicentric	NN
cord-022561-rv5j1201	2515	18	form	form	NN
cord-022561-rv5j1201	2515	19	,	,	,
cord-022561-rv5j1201	2515	20	with	with	IN
cord-022561-rv5j1201	2515	21	visceral	visceral	JJ
cord-022561-rv5j1201	2515	22	lymph	lymph	NN
cord-022561-rv5j1201	2515	23	nodes	node	NNS
cord-022561-rv5j1201	2515	24	reportedly	reportedly	RB
cord-022561-rv5j1201	2515	25	more	more	RBR
cord-022561-rv5j1201	2515	26	commonly	commonly	RB
cord-022561-rv5j1201	2515	27	involved	involve	VBN
cord-022561-rv5j1201	2515	28	than	than	IN
cord-022561-rv5j1201	2515	29	peripheral	peripheral	JJ
cord-022561-rv5j1201	2515	30	nodes	node	NNS
cord-022561-rv5j1201	2515	31	.	.	.
cord-022561-rv5j1201	2516	1	A	a	DT
cord-022561-rv5j1201	2516	2	recent	recent	JJ
cord-022561-rv5j1201	2516	3	study	study	NN
cord-022561-rv5j1201	2516	4	of	of	IN
cord-022561-rv5j1201	2516	5	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2516	6	in	in	IN
cord-022561-rv5j1201	2516	7	17	17	CD
cord-022561-rv5j1201	2516	8	pigs	pig	NNS
cord-022561-rv5j1201	2516	9	found	find	VBD
cord-022561-rv5j1201	2516	10	the	the	DT
cord-022561-rv5j1201	2516	11	majority	majority	NN
cord-022561-rv5j1201	2516	12	to	to	TO
cord-022561-rv5j1201	2516	13	be	be	VB
cord-022561-rv5j1201	2516	14	multicentric	multicentric	JJ
cord-022561-rv5j1201	2516	15	,	,	,
cord-022561-rv5j1201	2516	16	and	and	CC
cord-022561-rv5j1201	2516	17	subtypes	subtype	NNS
cord-022561-rv5j1201	2516	18	included	include	VBD
cord-022561-rv5j1201	2516	19	the	the	DT
cord-022561-rv5j1201	2516	20	following	following	NN
cord-022561-rv5j1201	2516	21	:	:	:
cord-022561-rv5j1201	2516	22	B	B	NNP
cord-022561-rv5j1201	2516	23	lymphoblastic	lymphoblastic	NNP
cord-022561-rv5j1201	2516	24	leukemia	leukemia	NN
cord-022561-rv5j1201	2516	25	/	/	SYM
cord-022561-rv5j1201	2516	26	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2516	27	,	,	,
cord-022561-rv5j1201	2516	28	follicular	follicular	JJ
cord-022561-rv5j1201	2516	29	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2516	30	,	,	,
cord-022561-rv5j1201	2516	31	diffuse	diffuse	JJ
cord-022561-rv5j1201	2516	32	and	and	CC
cord-022561-rv5j1201	2516	33	intestinal	intestinal	JJ
cord-022561-rv5j1201	2516	34	large	large	JJ
cord-022561-rv5j1201	2516	35	B	b	NN
cord-022561-rv5j1201	2516	36	cell	cell	NN
cord-022561-rv5j1201	2516	37	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2516	38	,	,	,
cord-022561-rv5j1201	2516	39	and	and	CC
cord-022561-rv5j1201	2516	40	peripheral	peripheral	JJ
cord-022561-rv5j1201	2516	41	T	T	NNP
cord-022561-rv5j1201	2516	42	cell	cell	NN
cord-022561-rv5j1201	2516	43	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2516	44	.	.	.
cord-022561-rv5j1201	2517	1	One	one	CD
cord-022561-rv5j1201	2517	2	case	case	NN
cord-022561-rv5j1201	2517	3	each	each	DT
cord-022561-rv5j1201	2517	4	of	of	IN
cord-022561-rv5j1201	2517	5	thymic	thymic	JJ
cord-022561-rv5j1201	2517	6	B	b	NN
cord-022561-rv5j1201	2517	7	cell	cell	NN
cord-022561-rv5j1201	2517	8	and	and	CC
cord-022561-rv5j1201	2517	9	T	t	NN
cord-022561-rv5j1201	2517	10	cell	cell	NN
cord-022561-rv5j1201	2517	11	lymphomas	lymphoma	NNS
cord-022561-rv5j1201	2517	12	were	be	VBD
cord-022561-rv5j1201	2517	13	also	also	RB
cord-022561-rv5j1201	2517	14	described	describe	VBN
cord-022561-rv5j1201	2517	15	.	.	.
cord-022561-rv5j1201	2518	1	Several	several	JJ
cord-022561-rv5j1201	2518	2	types	type	NNS
cord-022561-rv5j1201	2518	3	of	of	IN
cord-022561-rv5j1201	2518	4	severe	severe	JJ
cord-022561-rv5j1201	2518	5	combined	combine	VBN
cord-022561-rv5j1201	2518	6	immunodeficiency	immunodeficiency	NN
cord-022561-rv5j1201	2518	7	diseases	disease	NNS
cord-022561-rv5j1201	2518	8	have	have	VBP
cord-022561-rv5j1201	2518	9	been	be	VBN
cord-022561-rv5j1201	2518	10	described	describe	VBN
cord-022561-rv5j1201	2518	11	in	in	IN
cord-022561-rv5j1201	2518	12	dogs	dog	NNS
cord-022561-rv5j1201	2518	13	.	.	.
cord-022561-rv5j1201	2519	1	A	a	DT
cord-022561-rv5j1201	2519	2	mutation	mutation	NN
cord-022561-rv5j1201	2519	3	in	in	IN
cord-022561-rv5j1201	2519	4	DNA	DNA	NNP
cord-022561-rv5j1201	2519	5	-	-	HYPH
cord-022561-rv5j1201	2519	6	PKcs	PKcs	NNP
cord-022561-rv5j1201	2519	7	(	(	-LRB-
cord-022561-rv5j1201	2519	8	similar	similar	JJ
cord-022561-rv5j1201	2519	9	to	to	IN
cord-022561-rv5j1201	2519	10	Arabian	arabian	JJ
cord-022561-rv5j1201	2519	11	horses	horse	NNS
cord-022561-rv5j1201	2519	12	)	)	-RRB-
cord-022561-rv5j1201	2519	13	with	with	IN
cord-022561-rv5j1201	2519	14	an	an	DT
cord-022561-rv5j1201	2519	15	autosomal	autosomal	JJ
cord-022561-rv5j1201	2519	16	recessive	recessive	JJ
cord-022561-rv5j1201	2519	17	mode	mode	NN
cord-022561-rv5j1201	2519	18	of	of	IN
cord-022561-rv5j1201	2519	19	inheritance	inheritance	NN
cord-022561-rv5j1201	2519	20	is	be	VBZ
cord-022561-rv5j1201	2519	21	seen	see	VBN
cord-022561-rv5j1201	2519	22	in	in	IN
cord-022561-rv5j1201	2519	23	Jack	Jack	NNP
cord-022561-rv5j1201	2519	24	Russell	Russell	NNP
cord-022561-rv5j1201	2519	25	terriers	terrier	NNS
cord-022561-rv5j1201	2519	26	.	.	.
cord-022561-rv5j1201	2520	1	An	an	DT
cord-022561-rv5j1201	2520	2	X	x	NN
cord-022561-rv5j1201	2520	3	-	-	HYPH
cord-022561-rv5j1201	2520	4	linked	link	VBN
cord-022561-rv5j1201	2520	5	form	form	NN
cord-022561-rv5j1201	2520	6	of	of	IN
cord-022561-rv5j1201	2520	7	severe	severe	JJ
cord-022561-rv5j1201	2520	8	combined	combine	VBN
cord-022561-rv5j1201	2520	9	immunodeficiency	immunodeficiency	NN
cord-022561-rv5j1201	2520	10	disease	disease	NN
cord-022561-rv5j1201	2520	11	is	be	VBZ
cord-022561-rv5j1201	2520	12	well	well	RB
cord-022561-rv5j1201	2520	13	described	describe	VBN
cord-022561-rv5j1201	2520	14	in	in	IN
cord-022561-rv5j1201	2520	15	basset	basset	NN
cord-022561-rv5j1201	2520	16	hounds	hound	NNS
cord-022561-rv5j1201	2520	17	and	and	CC
cord-022561-rv5j1201	2520	18	is	be	VBZ
cord-022561-rv5j1201	2520	19	caused	cause	VBN
cord-022561-rv5j1201	2520	20	by	by	IN
cord-022561-rv5j1201	2520	21	mutations	mutation	NNS
cord-022561-rv5j1201	2520	22	in	in	IN
cord-022561-rv5j1201	2520	23	the	the	DT
cord-022561-rv5j1201	2520	24	common	common	JJ
cord-022561-rv5j1201	2520	25	γ	γ	NN
cord-022561-rv5j1201	2520	26	-	-	HYPH
cord-022561-rv5j1201	2520	27	chain	chain	NN
cord-022561-rv5j1201	2520	28	(	(	-LRB-
cord-022561-rv5j1201	2520	29	γc	γc	NN
cord-022561-rv5j1201	2520	30	)	)	-RRB-
cord-022561-rv5j1201	2520	31	subunit	subunit	NN
cord-022561-rv5j1201	2520	32	of	of	IN
cord-022561-rv5j1201	2520	33	the	the	DT
cord-022561-rv5j1201	2520	34	receptors	receptor	NNS
cord-022561-rv5j1201	2520	35	for	for	IN
cord-022561-rv5j1201	2520	36	IL-2	IL-2	NNP
cord-022561-rv5j1201	2520	37	,	,	,
cord-022561-rv5j1201	2520	38	IL-4	IL-4	NNP
cord-022561-rv5j1201	2520	39	,	,	,
cord-022561-rv5j1201	2520	40	IL-7	IL-7	NNP
cord-022561-rv5j1201	2520	41	,	,	,
cord-022561-rv5j1201	2520	42	IL-9	IL-9	NNP
cord-022561-rv5j1201	2520	43	,	,	,
cord-022561-rv5j1201	2520	44	IL-15	IL-15	NNP
cord-022561-rv5j1201	2520	45	,	,	,
cord-022561-rv5j1201	2520	46	and	and	CC
cord-022561-rv5j1201	2520	47	IL-21	IL-21	NNP
cord-022561-rv5j1201	2520	48	.	.	.
cord-022561-rv5j1201	2521	1	A	a	DT
cord-022561-rv5j1201	2521	2	similar	similar	JJ
cord-022561-rv5j1201	2521	3	disease	disease	NN
cord-022561-rv5j1201	2521	4	is	be	VBZ
cord-022561-rv5j1201	2521	5	seen	see	VBN
cord-022561-rv5j1201	2521	6	in	in	IN
cord-022561-rv5j1201	2521	7	Cardigan	Cardigan	NNP
cord-022561-rv5j1201	2521	8	Welsh	welsh	JJ
cord-022561-rv5j1201	2521	9	corgi	corgi	NN
cord-022561-rv5j1201	2521	10	puppies	puppy	NNS
cord-022561-rv5j1201	2521	11	,	,	,
cord-022561-rv5j1201	2521	12	though	though	IN
cord-022561-rv5j1201	2521	13	it	-PRON-	PRP
cord-022561-rv5j1201	2521	14	is	be	VBZ
cord-022561-rv5j1201	2521	15	an	an	DT
cord-022561-rv5j1201	2521	16	autosomal	autosomal	JJ
cord-022561-rv5j1201	2521	17	mode	mode	NN
cord-022561-rv5j1201	2521	18	of	of	IN
cord-022561-rv5j1201	2521	19	inheritance	inheritance	NN
cord-022561-rv5j1201	2521	20	in	in	IN
cord-022561-rv5j1201	2521	21	this	this	DT
cord-022561-rv5j1201	2521	22	breed	breed	NN
cord-022561-rv5j1201	2521	23	.	.	.
cord-022561-rv5j1201	2522	1	The	the	DT
cord-022561-rv5j1201	2522	2	mutation	mutation	NN
cord-022561-rv5j1201	2522	3	inhibits	inhibit	VBZ
cord-022561-rv5j1201	2522	4	the	the	DT
cord-022561-rv5j1201	2522	5	signal	signal	NN
cord-022561-rv5j1201	2522	6	transduction	transduction	NN
cord-022561-rv5j1201	2522	7	pathways	pathway	NNS
cord-022561-rv5j1201	2522	8	initiated	initiate	VBN
cord-022561-rv5j1201	2522	9	by	by	IN
cord-022561-rv5j1201	2522	10	any	any	DT
cord-022561-rv5j1201	2522	11	of	of	IN
cord-022561-rv5j1201	2522	12	these	these	DT
cord-022561-rv5j1201	2522	13	cytokines	cytokine	NNS
cord-022561-rv5j1201	2522	14	,	,	,
cord-022561-rv5j1201	2522	15	which	which	WDT
cord-022561-rv5j1201	2522	16	are	be	VBP
cord-022561-rv5j1201	2522	17	critical	critical	JJ
cord-022561-rv5j1201	2522	18	for	for	IN
cord-022561-rv5j1201	2522	19	the	the	DT
cord-022561-rv5j1201	2522	20	proliferation	proliferation	NN
cord-022561-rv5j1201	2522	21	,	,	,
cord-022561-rv5j1201	2522	22	differentiation	differentiation	NN
cord-022561-rv5j1201	2522	23	,	,	,
cord-022561-rv5j1201	2522	24	survival	survival	NN
cord-022561-rv5j1201	2522	25	,	,	,
cord-022561-rv5j1201	2522	26	and	and	CC
cord-022561-rv5j1201	2522	27	function	function	NN
cord-022561-rv5j1201	2522	28	of	of	IN
cord-022561-rv5j1201	2522	29	B	b	NN
cord-022561-rv5j1201	2522	30	and	and	CC
cord-022561-rv5j1201	2522	31	T	t	NN
cord-022561-rv5j1201	2522	32	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	2522	33	.	.	.
cord-022561-rv5j1201	2523	1	Affected	affected	JJ
cord-022561-rv5j1201	2523	2	dogs	dog	NNS
cord-022561-rv5j1201	2523	3	have	have	VBP
cord-022561-rv5j1201	2523	4	normal	normal	JJ
cord-022561-rv5j1201	2523	5	numbers	number	NNS
cord-022561-rv5j1201	2523	6	of	of	IN
cord-022561-rv5j1201	2523	7	circulating	circulate	VBG
cord-022561-rv5j1201	2523	8	B	b	NN
cord-022561-rv5j1201	2523	9	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	2523	10	that	that	WDT
cord-022561-rv5j1201	2523	11	are	be	VBP
cord-022561-rv5j1201	2523	12	unable	unable	JJ
cord-022561-rv5j1201	2523	13	to	to	TO
cord-022561-rv5j1201	2523	14	class	class	NN
cord-022561-rv5j1201	2523	15	switch	switch	NN
cord-022561-rv5j1201	2523	16	to	to	IN
cord-022561-rv5j1201	2523	17	IgG	IgG	NNP
cord-022561-rv5j1201	2523	18	or	or	CC
cord-022561-rv5j1201	2523	19	IgA	IgA	NNP
cord-022561-rv5j1201	2523	20	and	and	CC
cord-022561-rv5j1201	2523	21	reduced	reduce	VBN
cord-022561-rv5j1201	2523	22	numbers	number	NNS
cord-022561-rv5j1201	2523	23	of	of	IN
cord-022561-rv5j1201	2523	24	T	t	NN
cord-022561-rv5j1201	2523	25	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	2523	26	,	,	,
cord-022561-rv5j1201	2523	27	which	which	WDT
cord-022561-rv5j1201	2523	28	are	be	VBP
cord-022561-rv5j1201	2523	29	nonfunctional	nonfunctional	JJ
cord-022561-rv5j1201	2523	30	due	due	IN
cord-022561-rv5j1201	2523	31	to	to	IN
cord-022561-rv5j1201	2523	32	the	the	DT
cord-022561-rv5j1201	2523	33	inability	inability	NN
cord-022561-rv5j1201	2523	34	to	to	TO
cord-022561-rv5j1201	2523	35	express	express	VB
cord-022561-rv5j1201	2523	36	IL	IL	NNP
cord-022561-rv5j1201	2523	37	receptors	receptor	NNS
cord-022561-rv5j1201	2523	38	.	.	.
cord-022561-rv5j1201	2524	1	Affected	affected	JJ
cord-022561-rv5j1201	2524	2	puppies	puppy	NNS
cord-022561-rv5j1201	2524	3	are	be	VBP
cord-022561-rv5j1201	2524	4	remarkably	remarkably	RB
cord-022561-rv5j1201	2524	5	susceptible	susceptible	JJ
cord-022561-rv5j1201	2524	6	to	to	IN
cord-022561-rv5j1201	2524	7	bacterial	bacterial	JJ
cord-022561-rv5j1201	2524	8	and	and	CC
cord-022561-rv5j1201	2524	9	viral	viral	JJ
cord-022561-rv5j1201	2524	10	infections	infection	NNS
cord-022561-rv5j1201	2524	11	and	and	CC
cord-022561-rv5j1201	2524	12	rarely	rarely	RB
cord-022561-rv5j1201	2524	13	survive	survive	VBP
cord-022561-rv5j1201	2524	14	past	past	IN
cord-022561-rv5j1201	2524	15	3	3	CD
cord-022561-rv5j1201	2524	16	to	to	IN
cord-022561-rv5j1201	2524	17	4	4	CD
cord-022561-rv5j1201	2524	18	months	month	NNS
cord-022561-rv5j1201	2524	19	of	of	IN
cord-022561-rv5j1201	2524	20	age	age	NN
cord-022561-rv5j1201	2524	21	.	.	.
cord-022561-rv5j1201	2525	1	The	the	DT
cord-022561-rv5j1201	2525	2	thymus	thymus	NN
cord-022561-rv5j1201	2525	3	of	of	IN
cord-022561-rv5j1201	2525	4	these	these	DT
cord-022561-rv5j1201	2525	5	dogs	dog	NNS
cord-022561-rv5j1201	2525	6	is	be	VBZ
cord-022561-rv5j1201	2525	7	small	small	JJ
cord-022561-rv5j1201	2525	8	and	and	CC
cord-022561-rv5j1201	2525	9	consists	consist	VBZ
cord-022561-rv5j1201	2525	10	of	of	IN
cord-022561-rv5j1201	2525	11	only	only	JJ
cord-022561-rv5j1201	2525	12	small	small	JJ
cord-022561-rv5j1201	2525	13	dysplastic	dysplastic	JJ
cord-022561-rv5j1201	2525	14	lobules	lobule	NNS
cord-022561-rv5j1201	2525	15	with	with	IN
cord-022561-rv5j1201	2525	16	a	a	DT
cord-022561-rv5j1201	2525	17	few	few	JJ
cord-022561-rv5j1201	2525	18	of	of	IN
cord-022561-rv5j1201	2525	19	Hassall	Hassall	NNP
cord-022561-rv5j1201	2525	20	's	's	POS
cord-022561-rv5j1201	2525	21	corpuscles	corpuscle	NNS
cord-022561-rv5j1201	2525	22	.	.	.
cord-022561-rv5j1201	2526	1	Tonsils	tonsil	NNS
cord-022561-rv5j1201	2526	2	,	,	,
cord-022561-rv5j1201	2526	3	lymph	lymph	NN
cord-022561-rv5j1201	2526	4	nodes	node	NNS
cord-022561-rv5j1201	2526	5	,	,	,
cord-022561-rv5j1201	2526	6	and	and	CC
cord-022561-rv5j1201	2526	7	Peyer	Peyer	NNP
cord-022561-rv5j1201	2526	8	's	's	POS
cord-022561-rv5j1201	2526	9	patches	patch	NNS
cord-022561-rv5j1201	2526	10	are	be	VBP
cord-022561-rv5j1201	2526	11	often	often	RB
cord-022561-rv5j1201	2526	12	grossly	grossly	RB
cord-022561-rv5j1201	2526	13	unidentifiable	unidentifiable	JJ
cord-022561-rv5j1201	2526	14	due	due	IN
cord-022561-rv5j1201	2526	15	to	to	IN
cord-022561-rv5j1201	2526	16	the	the	DT
cord-022561-rv5j1201	2526	17	severe	severe	JJ
cord-022561-rv5j1201	2526	18	lymphocyte	lymphocyte	NN
cord-022561-rv5j1201	2526	19	hypoplasia	hypoplasia	NN
cord-022561-rv5j1201	2526	20	.	.	.
cord-022561-rv5j1201	2527	1	Congenital	congenital	JJ
cord-022561-rv5j1201	2527	2	immunodeficiency	immunodeficiency	NN
cord-022561-rv5j1201	2527	3	diseases	disease	NNS
cord-022561-rv5j1201	2527	4	are	be	VBP
cord-022561-rv5j1201	2527	5	also	also	RB
cord-022561-rv5j1201	2527	6	discussed	discuss	VBN
cord-022561-rv5j1201	2527	7	in	in	IN
cord-022561-rv5j1201	2527	8	detail	detail	NN
cord-022561-rv5j1201	2527	9	in	in	IN
cord-022561-rv5j1201	2527	10	Chapter	chapter	NN
cord-022561-rv5j1201	2527	11	5	5	CD
cord-022561-rv5j1201	2527	12	.	.	.
cord-022561-rv5j1201	2528	1	Thymic	thymic	JJ
cord-022561-rv5j1201	2528	2	hemorrhage	hemorrhage	NN
cord-022561-rv5j1201	2528	3	and	and	CC
cord-022561-rv5j1201	2528	4	hematomas	hematoma	NNS
cord-022561-rv5j1201	2528	5	have	have	VBP
cord-022561-rv5j1201	2528	6	been	be	VBN
cord-022561-rv5j1201	2528	7	reported	report	VBN
cord-022561-rv5j1201	2528	8	in	in	IN
cord-022561-rv5j1201	2528	9	dogs	dog	NNS
cord-022561-rv5j1201	2528	10	and	and	CC
cord-022561-rv5j1201	2528	11	are	be	VBP
cord-022561-rv5j1201	2528	12	most	most	RBS
cord-022561-rv5j1201	2528	13	often	often	RB
cord-022561-rv5j1201	2528	14	seen	see	VBN
cord-022561-rv5j1201	2528	15	in	in	IN
cord-022561-rv5j1201	2528	16	young	young	JJ
cord-022561-rv5j1201	2528	17	animals	animal	NNS
cord-022561-rv5j1201	2528	18	.	.	.
cord-022561-rv5j1201	2529	1	A	a	DT
cord-022561-rv5j1201	2529	2	variety	variety	NN
cord-022561-rv5j1201	2529	3	of	of	IN
cord-022561-rv5j1201	2529	4	causes	cause	NNS
cord-022561-rv5j1201	2529	5	are	be	VBP
cord-022561-rv5j1201	2529	6	described	describe	VBN
cord-022561-rv5j1201	2529	7	,	,	,
cord-022561-rv5j1201	2529	8	including	include	VBG
cord-022561-rv5j1201	2529	9	ingestion	ingestion	NN
cord-022561-rv5j1201	2529	10	of	of	IN
cord-022561-rv5j1201	2529	11	anticoagulant	anticoagulant	JJ
cord-022561-rv5j1201	2529	12	rodenticides	rodenticide	NNS
cord-022561-rv5j1201	2529	13	(	(	-LRB-
cord-022561-rv5j1201	2529	14	warfarin	warfarin	NN
cord-022561-rv5j1201	2529	15	,	,	,
cord-022561-rv5j1201	2529	16	dicumarol	dicumarol	NNP
cord-022561-rv5j1201	2529	17	,	,	,
cord-022561-rv5j1201	2529	18	diphacinone	diphacinone	NNP
cord-022561-rv5j1201	2529	19	,	,	,
cord-022561-rv5j1201	2529	20	and	and	CC
cord-022561-rv5j1201	2529	21	brodifacoum	brodifacoum	NNP
cord-022561-rv5j1201	2529	22	)	)	-RRB-
cord-022561-rv5j1201	2529	23	,	,	,
cord-022561-rv5j1201	2529	24	dissecting	dissect	VBG
cord-022561-rv5j1201	2529	25	aortic	aortic	JJ
cord-022561-rv5j1201	2529	26	aneurysms	aneurysm	NNS
cord-022561-rv5j1201	2529	27	,	,	,
cord-022561-rv5j1201	2529	28	trauma	trauma	NN
cord-022561-rv5j1201	2529	29	(	(	-LRB-
cord-022561-rv5j1201	2529	30	e.g.	e.g.	RB
cord-022561-rv5j1201	2529	31	,	,	,
cord-022561-rv5j1201	2529	32	automobile	automobile	NN
cord-022561-rv5j1201	2529	33	accident	accident	NN
cord-022561-rv5j1201	2529	34	)	)	-RRB-
cord-022561-rv5j1201	2529	35	,	,	,
cord-022561-rv5j1201	2529	36	and	and	CC
cord-022561-rv5j1201	2529	37	idiopathic/	idiopathic/	CD
cord-022561-rv5j1201	2529	38	spontaneous	spontaneous	JJ
cord-022561-rv5j1201	2529	39	.	.	.
cord-022561-rv5j1201	2530	1	Histologically	histologically	RB
cord-022561-rv5j1201	2530	2	,	,	,
cord-022561-rv5j1201	2530	3	hemorrhage	hemorrhage	NN
cord-022561-rv5j1201	2530	4	variably	variably	RB
cord-022561-rv5j1201	2530	5	expands	expand	VBZ
cord-022561-rv5j1201	2530	6	the	the	DT
cord-022561-rv5j1201	2530	7	thymic	thymic	JJ
cord-022561-rv5j1201	2530	8	lobules	lobule	NNS
cord-022561-rv5j1201	2530	9	and	and	CC
cord-022561-rv5j1201	2530	10	septa	septa	NNP
cord-022561-rv5j1201	2530	11	,	,	,
cord-022561-rv5j1201	2530	12	and	and	CC
cord-022561-rv5j1201	2530	13	in	in	IN
cord-022561-rv5j1201	2530	14	severe	severe	JJ
cord-022561-rv5j1201	2530	15	cases	case	NNS
cord-022561-rv5j1201	2530	16	the	the	DT
cord-022561-rv5j1201	2530	17	lobular	lobular	NNP
cord-022561-rv5j1201	2530	18	architecture	architecture	NN
cord-022561-rv5j1201	2530	19	is	be	VBZ
cord-022561-rv5j1201	2530	20	obscured	obscure	VBN
cord-022561-rv5j1201	2530	21	by	by	IN
cord-022561-rv5j1201	2530	22	hemorrhage	hemorrhage	NN
cord-022561-rv5j1201	2530	23	.	.	.
cord-022561-rv5j1201	2531	1	In	in	IN
cord-022561-rv5j1201	2531	2	cases	case	NNS
cord-022561-rv5j1201	2531	3	of	of	IN
cord-022561-rv5j1201	2531	4	anticoagulant	anticoagulant	JJ
cord-022561-rv5j1201	2531	5	rodenticide	rodenticide	NN
cord-022561-rv5j1201	2531	6	toxicosis	toxicosis	NN
cord-022561-rv5j1201	2531	7	,	,	,
cord-022561-rv5j1201	2531	8	the	the	DT
cord-022561-rv5j1201	2531	9	medulla	medulla	NN
cord-022561-rv5j1201	2531	10	appears	appear	VBZ
cord-022561-rv5j1201	2531	11	to	to	TO
cord-022561-rv5j1201	2531	12	be	be	VB
cord-022561-rv5j1201	2531	13	the	the	DT
cord-022561-rv5j1201	2531	14	main	main	JJ
cord-022561-rv5j1201	2531	15	site	site	NN
cord-022561-rv5j1201	2531	16	of	of	IN
cord-022561-rv5j1201	2531	17	hemorrhage	hemorrhage	NN
cord-022561-rv5j1201	2531	18	.	.	.
cord-022561-rv5j1201	2532	1	See	see	VB
cord-022561-rv5j1201	2532	2	Uniform	Uniform	NNP
cord-022561-rv5j1201	2532	3	Splenomegaly	Splenomegaly	NNP
cord-022561-rv5j1201	2532	4	with	with	IN
cord-022561-rv5j1201	2532	5	a	a	DT
cord-022561-rv5j1201	2532	6	Bloody	Bloody	NNP
cord-022561-rv5j1201	2532	7	Consistency	Consistency	NNP
cord-022561-rv5j1201	2532	8	(	(	-LRB-
cord-022561-rv5j1201	2532	9	also	also	RB
cord-022561-rv5j1201	2532	10	see	see	VB
cord-022561-rv5j1201	2532	11	Figs	fig	NNS
cord-022561-rv5j1201	2532	12	.	.	.
cord-022561-rv5j1201	2533	1	7	7	LS
cord-022561-rv5j1201	2533	2	-	-	SYM
cord-022561-rv5j1201	2533	3	72	72	CD
cord-022561-rv5j1201	2533	4	and	and	CC
cord-022561-rv5j1201	2533	5	7	7	CD
cord-022561-rv5j1201	2533	6	-	-	SYM
cord-022561-rv5j1201	2533	7	73	73	CD
cord-022561-rv5j1201	2533	8	)	)	-RRB-
cord-022561-rv5j1201	2533	9	.	.	.
cord-022561-rv5j1201	2534	1	See	see	VB
cord-022561-rv5j1201	2534	2	the	the	DT
cord-022561-rv5j1201	2534	3	section	section	NN
cord-022561-rv5j1201	2534	4	on	on	IN
cord-022561-rv5j1201	2534	5	Splenic	Splenic	NNP
cord-022561-rv5j1201	2534	6	Nodules	Nodules	NNP
cord-022561-rv5j1201	2534	7	with	with	IN
cord-022561-rv5j1201	2534	8	a	a	DT
cord-022561-rv5j1201	2534	9	Bloody	Bloody	NNP
cord-022561-rv5j1201	2534	10	Consistency	Consistency	NNP
cord-022561-rv5j1201	2534	11	for	for	IN
cord-022561-rv5j1201	2534	12	discussion	discussion	NN
cord-022561-rv5j1201	2534	13	on	on	IN
cord-022561-rv5j1201	2534	14	splenic	splenic	JJ
cord-022561-rv5j1201	2534	15	hematomas	hematoma	NNS
cord-022561-rv5j1201	2534	16	(	(	-LRB-
cord-022561-rv5j1201	2534	17	including	include	VBG
cord-022561-rv5j1201	2534	18	those	those	DT
cord-022561-rv5j1201	2534	19	induced	induce	VBN
cord-022561-rv5j1201	2534	20	by	by	IN
cord-022561-rv5j1201	2534	21	nodular	nodular	JJ
cord-022561-rv5j1201	2534	22	hyperplasia	hyperplasia	NN
cord-022561-rv5j1201	2534	23	or	or	CC
cord-022561-rv5j1201	2534	24	occurring	occur	VBG
cord-022561-rv5j1201	2534	25	with	with	IN
cord-022561-rv5j1201	2534	26	hemangiosarcoma	hemangiosarcoma	NN
cord-022561-rv5j1201	2534	27	)	)	-RRB-
cord-022561-rv5j1201	2534	28	,	,	,
cord-022561-rv5j1201	2534	29	incomplete	incomplete	JJ
cord-022561-rv5j1201	2534	30	splenic	splenic	JJ
cord-022561-rv5j1201	2534	31	contraction	contraction	NN
cord-022561-rv5j1201	2534	32	,	,	,
cord-022561-rv5j1201	2534	33	acute	acute	JJ
cord-022561-rv5j1201	2534	34	splenic	splenic	JJ
cord-022561-rv5j1201	2534	35	infarcts	infarct	NNS
cord-022561-rv5j1201	2534	36	,	,	,
cord-022561-rv5j1201	2534	37	and	and	CC
cord-022561-rv5j1201	2534	38	hemangiosarcomas	hemangiosarcomas	NN
cord-022561-rv5j1201	2534	39	.	.	.
cord-022561-rv5j1201	2535	1	Porcine	porcine	JJ
cord-022561-rv5j1201	2535	2	reproductive	reproductive	JJ
cord-022561-rv5j1201	2535	3	and	and	CC
cord-022561-rv5j1201	2535	4	respiratory	respiratory	JJ
cord-022561-rv5j1201	2535	5	syndrome	syndrome	NN
cord-022561-rv5j1201	2535	6	(	(	-LRB-
cord-022561-rv5j1201	2535	7	PRRS	PRRS	NNP
cord-022561-rv5j1201	2535	8	)	)	-RRB-
cord-022561-rv5j1201	2535	9	is	be	VBZ
cord-022561-rv5j1201	2535	10	caused	cause	VBN
cord-022561-rv5j1201	2535	11	by	by	IN
cord-022561-rv5j1201	2535	12	an	an	DT
cord-022561-rv5j1201	2535	13	arterivirus	arterivirus	NN
cord-022561-rv5j1201	2535	14	and	and	CC
cord-022561-rv5j1201	2535	15	causes	cause	VBZ
cord-022561-rv5j1201	2535	16	two	two	CD
cord-022561-rv5j1201	2535	17	overlapping	overlap	VBG
cord-022561-rv5j1201	2535	18	clinical	clinical	JJ
cord-022561-rv5j1201	2535	19	syndromes	syndrome	NNS
cord-022561-rv5j1201	2535	20	:	:	:
cord-022561-rv5j1201	2535	21	reproductive	reproductive	JJ
cord-022561-rv5j1201	2535	22	failure	failure	NN
cord-022561-rv5j1201	2535	23	and	and	CC
cord-022561-rv5j1201	2535	24	respiratory	respiratory	JJ
cord-022561-rv5j1201	2535	25	disease	disease	NN
cord-022561-rv5j1201	2535	26	.	.	.
cord-022561-rv5j1201	2536	1	The	the	DT
cord-022561-rv5j1201	2536	2	virus	virus	NN
cord-022561-rv5j1201	2536	3	is	be	VBZ
cord-022561-rv5j1201	2536	4	transmitted	transmit	VBN
cord-022561-rv5j1201	2536	5	by	by	IN
cord-022561-rv5j1201	2536	6	contact	contact	NN
cord-022561-rv5j1201	2536	7	with	with	IN
cord-022561-rv5j1201	2536	8	body	body	NN
cord-022561-rv5j1201	2536	9	fluids	fluid	NNS
cord-022561-rv5j1201	2536	10	(	(	-LRB-
cord-022561-rv5j1201	2536	11	saliva	saliva	NN
cord-022561-rv5j1201	2536	12	,	,	,
cord-022561-rv5j1201	2536	13	mucus	mucus	NN
cord-022561-rv5j1201	2536	14	,	,	,
cord-022561-rv5j1201	2536	15	serum	serum	NN
cord-022561-rv5j1201	2536	16	,	,	,
cord-022561-rv5j1201	2536	17	urine	urine	NN
cord-022561-rv5j1201	2536	18	,	,	,
cord-022561-rv5j1201	2536	19	and	and	CC
cord-022561-rv5j1201	2536	20	mammary	mammary	JJ
cord-022561-rv5j1201	2536	21	secretions	secretion	NNS
cord-022561-rv5j1201	2536	22	and	and	CC
cord-022561-rv5j1201	2536	23	from	from	IN
cord-022561-rv5j1201	2536	24	contact	contact	NN
cord-022561-rv5j1201	2536	25	with	with	IN
cord-022561-rv5j1201	2536	26	semen	semen	NN
cord-022561-rv5j1201	2536	27	during	during	IN
cord-022561-rv5j1201	2536	28	coitus	coitus	NN
cord-022561-rv5j1201	2536	29	)	)	-RRB-
cord-022561-rv5j1201	2536	30	,	,	,
cord-022561-rv5j1201	2536	31	but	but	CC
cord-022561-rv5j1201	2536	32	often	often	RB
cord-022561-rv5j1201	2536	33	it	-PRON-	PRP
cord-022561-rv5j1201	2536	34	first	first	RB
cord-022561-rv5j1201	2536	35	colonizes	colonize	VBZ
cord-022561-rv5j1201	2536	36	tonsils	tonsil	NNS
cord-022561-rv5j1201	2536	37	or	or	CC
cord-022561-rv5j1201	2536	38	upper	upper	JJ
cord-022561-rv5j1201	2536	39	respiratory	respiratory	JJ
cord-022561-rv5j1201	2536	40	tract	tract	NN
cord-022561-rv5j1201	2536	41	.	.	.
cord-022561-rv5j1201	2537	1	The	the	DT
cord-022561-rv5j1201	2537	2	virus	virus	NN
cord-022561-rv5j1201	2537	3	has	have	VBZ
cord-022561-rv5j1201	2537	4	a	a	DT
cord-022561-rv5j1201	2537	5	predilection	predilection	NN
cord-022561-rv5j1201	2537	6	for	for	IN
cord-022561-rv5j1201	2537	7	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	2537	8	tissues	tissue	NNS
cord-022561-rv5j1201	2537	9	(	(	-LRB-
cord-022561-rv5j1201	2537	10	spleen	spleen	NN
cord-022561-rv5j1201	2537	11	,	,	,
cord-022561-rv5j1201	2537	12	thymus	thymus	NN
cord-022561-rv5j1201	2537	13	,	,	,
cord-022561-rv5j1201	2537	14	tonsils	tonsil	NNS
cord-022561-rv5j1201	2537	15	,	,	,
cord-022561-rv5j1201	2537	16	lymph	lymph	NN
cord-022561-rv5j1201	2537	17	nodes	node	NNS
cord-022561-rv5j1201	2537	18	,	,	,
cord-022561-rv5j1201	2537	19	Peyer	Peyer	NNP
cord-022561-rv5j1201	2537	20	's	's	POS
cord-022561-rv5j1201	2537	21	patches	patch	NNS
cord-022561-rv5j1201	2537	22	)	)	-RRB-
cord-022561-rv5j1201	2537	23	.	.	.
cord-022561-rv5j1201	2538	1	Viral	viral	JJ
cord-022561-rv5j1201	2538	2	replication	replication	NN
cord-022561-rv5j1201	2538	3	takes	take	VBZ
cord-022561-rv5j1201	2538	4	place	place	NN
cord-022561-rv5j1201	2538	5	in	in	IN
cord-022561-rv5j1201	2538	6	macrophages	macrophage	NNS
cord-022561-rv5j1201	2538	7	of	of	IN
cord-022561-rv5j1201	2538	8	the	the	DT
cord-022561-rv5j1201	2538	9	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	2538	10	tissues	tissue	NNS
cord-022561-rv5j1201	2538	11	and	and	CC
cord-022561-rv5j1201	2538	12	lungs	lung	NNS
cord-022561-rv5j1201	2538	13	,	,	,
cord-022561-rv5j1201	2538	14	though	though	IN
cord-022561-rv5j1201	2538	15	porcine	porcine	JJ
cord-022561-rv5j1201	2538	16	reproductive	reproductive	JJ
cord-022561-rv5j1201	2538	17	and	and	CC
cord-022561-rv5j1201	2538	18	respiratory	respiratory	JJ
cord-022561-rv5j1201	2538	19	syndrome	syndrome	NN
cord-022561-rv5j1201	2538	20	virus	virus	NN
cord-022561-rv5j1201	2538	21	antigen	antigen	NN
cord-022561-rv5j1201	2538	22	is	be	VBZ
cord-022561-rv5j1201	2538	23	found	find	VBN
cord-022561-rv5j1201	2538	24	in	in	IN
cord-022561-rv5j1201	2538	25	resident	resident	JJ
cord-022561-rv5j1201	2538	26	macrophages	macrophage	NNS
cord-022561-rv5j1201	2538	27	in	in	IN
cord-022561-rv5j1201	2538	28	many	many	JJ
cord-022561-rv5j1201	2538	29	tissues	tissue	NNS
cord-022561-rv5j1201	2538	30	and	and	CC
cord-022561-rv5j1201	2538	31	may	may	MD
cord-022561-rv5j1201	2538	32	persist	persist	VB
cord-022561-rv5j1201	2538	33	in	in	IN
cord-022561-rv5j1201	2538	34	tonsil	tonsil	NN
cord-022561-rv5j1201	2538	35	and	and	CC
cord-022561-rv5j1201	2538	36	lung	lung	NN
cord-022561-rv5j1201	2538	37	macrophages	macrophage	NNS
cord-022561-rv5j1201	2538	38	.	.	.
cord-022561-rv5j1201	2539	1	The	the	DT
cord-022561-rv5j1201	2539	2	result	result	NN
cord-022561-rv5j1201	2539	3	of	of	IN
cord-022561-rv5j1201	2539	4	this	this	DT
cord-022561-rv5j1201	2539	5	infection	infection	NN
cord-022561-rv5j1201	2539	6	is	be	VBZ
cord-022561-rv5j1201	2539	7	a	a	DT
cord-022561-rv5j1201	2539	8	reduction	reduction	NN
cord-022561-rv5j1201	2539	9	in	in	IN
cord-022561-rv5j1201	2539	10	the	the	DT
cord-022561-rv5j1201	2539	11	phagocytic	phagocytic	JJ
cord-022561-rv5j1201	2539	12	and	and	CC
cord-022561-rv5j1201	2539	13	functional	functional	JJ
cord-022561-rv5j1201	2539	14	capacity	capacity	NN
cord-022561-rv5j1201	2539	15	of	of	IN
cord-022561-rv5j1201	2539	16	macrophages	macrophage	NNS
cord-022561-rv5j1201	2539	17	of	of	IN
cord-022561-rv5j1201	2539	18	the	the	DT
cord-022561-rv5j1201	2539	19	monocytemacrophage	monocytemacrophage	NN
cord-022561-rv5j1201	2539	20	system	system	NN
cord-022561-rv5j1201	2539	21	.	.	.
cord-022561-rv5j1201	2540	1	As	as	IN
cord-022561-rv5j1201	2540	2	a	a	DT
cord-022561-rv5j1201	2540	3	consequence	consequence	NN
cord-022561-rv5j1201	2540	4	,	,	,
cord-022561-rv5j1201	2540	5	there	there	EX
cord-022561-rv5j1201	2540	6	is	be	VBZ
cord-022561-rv5j1201	2540	7	reduction	reduction	NN
cord-022561-rv5j1201	2540	8	in	in	IN
cord-022561-rv5j1201	2540	9	resistance	resistance	NN
cord-022561-rv5j1201	2540	10	to	to	IN
cord-022561-rv5j1201	2540	11	common	common	JJ
cord-022561-rv5j1201	2540	12	bacterial	bacterial	JJ
cord-022561-rv5j1201	2540	13	and	and	CC
cord-022561-rv5j1201	2540	14	viral	viral	JJ
cord-022561-rv5j1201	2540	15	pathogens	pathogen	NNS
cord-022561-rv5j1201	2540	16	.	.	.
cord-022561-rv5j1201	2541	1	Most	Most	JJS
cord-022561-rv5j1201	2541	2	porcine	porcine	JJ
cord-022561-rv5j1201	2541	3	reproductive	reproductive	JJ
cord-022561-rv5j1201	2541	4	and	and	CC
cord-022561-rv5j1201	2541	5	respiratory	respiratory	JJ
cord-022561-rv5j1201	2541	6	syndrome	syndrome	NN
cord-022561-rv5j1201	2541	7	-	-	HYPH
cord-022561-rv5j1201	2541	8	infected	infect	VBN
cord-022561-rv5j1201	2541	9	pigs	pig	NNS
cord-022561-rv5j1201	2541	10	are	be	VBP
cord-022561-rv5j1201	2541	11	coinfected	coinfecte	VBN
cord-022561-rv5j1201	2541	12	with	with	IN
cord-022561-rv5j1201	2541	13	one	one	CD
cord-022561-rv5j1201	2541	14	or	or	CC
cord-022561-rv5j1201	2541	15	more	more	JJR
cord-022561-rv5j1201	2541	16	pathogens	pathogen	NNS
cord-022561-rv5j1201	2541	17	,	,	,
cord-022561-rv5j1201	2541	18	including	include	VBG
cord-022561-rv5j1201	2541	19	Streptococcus	streptococcus	NN
cord-022561-rv5j1201	2541	20	suis	suis	NN
cord-022561-rv5j1201	2541	21	and	and	CC
cord-022561-rv5j1201	2541	22	Salmonella	Salmonella	NNP
cord-022561-rv5j1201	2541	23	choleraesuis	choleraesuis	NN
cord-022561-rv5j1201	2541	24	.	.	.
cord-022561-rv5j1201	2542	1	Infection	infection	NN
cord-022561-rv5j1201	2542	2	with	with	IN
cord-022561-rv5j1201	2542	3	Bordetella	Bordetella	NNP
cord-022561-rv5j1201	2542	4	bronchiseptica	bronchiseptica	NNP
cord-022561-rv5j1201	2542	5	and	and	CC
cord-022561-rv5j1201	2542	6	Mycoplasma	Mycoplasma	NNP
cord-022561-rv5j1201	2542	7	hyopneumoniae	hyopneumoniae	NNS
cord-022561-rv5j1201	2542	8	appear	appear	VBP
cord-022561-rv5j1201	2542	9	to	to	TO
cord-022561-rv5j1201	2542	10	increase	increase	VB
cord-022561-rv5j1201	2542	11	the	the	DT
cord-022561-rv5j1201	2542	12	duration	duration	NN
cord-022561-rv5j1201	2542	13	and	and	CC
cord-022561-rv5j1201	2542	14	severity	severity	NN
cord-022561-rv5j1201	2542	15	of	of	IN
cord-022561-rv5j1201	2542	16	the	the	DT
cord-022561-rv5j1201	2542	17	interstitial	interstitial	JJ
cord-022561-rv5j1201	2542	18	pneumonia	pneumonia	NN
cord-022561-rv5j1201	2542	19	.	.	.
cord-022561-rv5j1201	2543	1	The	the	DT
cord-022561-rv5j1201	2543	2	major	major	JJ
cord-022561-rv5j1201	2543	3	lesions	lesion	NNS
cord-022561-rv5j1201	2543	4	are	be	VBP
cord-022561-rv5j1201	2543	5	interstitial	interstitial	JJ
cord-022561-rv5j1201	2543	6	pneumonia	pneumonia	NN
cord-022561-rv5j1201	2543	7	and	and	CC
cord-022561-rv5j1201	2543	8	generalized	generalize	VBN
cord-022561-rv5j1201	2543	9	lymphadenopathy	lymphadenopathy	NN
cord-022561-rv5j1201	2543	10	,	,	,
cord-022561-rv5j1201	2543	11	and	and	CC
cord-022561-rv5j1201	2543	12	tracheobronchial	tracheobronchial	JJ
cord-022561-rv5j1201	2543	13	and	and	CC
cord-022561-rv5j1201	2543	14	mediastinal	mediastinal	JJ
cord-022561-rv5j1201	2543	15	lymph	lymph	NN
cord-022561-rv5j1201	2543	16	nodes	node	NNS
cord-022561-rv5j1201	2543	17	are	be	VBP
cord-022561-rv5j1201	2543	18	most	most	RBS
cord-022561-rv5j1201	2543	19	commonly	commonly	RB
cord-022561-rv5j1201	2543	20	affected	affect	VBN
cord-022561-rv5j1201	2543	21	.	.	.
cord-022561-rv5j1201	2544	1	Coinfections	coinfection	NNS
cord-022561-rv5j1201	2544	2	often	often	RB
cord-022561-rv5j1201	2544	3	complicate	complicate	VBP
cord-022561-rv5j1201	2544	4	the	the	DT
cord-022561-rv5j1201	2544	5	gross	gross	JJ
cord-022561-rv5j1201	2544	6	and	and	CC
cord-022561-rv5j1201	2544	7	histopathologic	histopathologic	JJ
cord-022561-rv5j1201	2544	8	changes	change	NNS
cord-022561-rv5j1201	2544	9	.	.	.
cord-022561-rv5j1201	2545	1	Lymph	lymph	NN
cord-022561-rv5j1201	2545	2	nodes	node	NNS
cord-022561-rv5j1201	2545	3	are	be	VBP
cord-022561-rv5j1201	2545	4	enlarged	enlarge	VBN
cord-022561-rv5j1201	2545	5	,	,	,
cord-022561-rv5j1201	2545	6	pale	pale	JJ
cord-022561-rv5j1201	2545	7	tan	tan	NNP
cord-022561-rv5j1201	2545	8	,	,	,
cord-022561-rv5j1201	2545	9	occasionally	occasionally	RB
cord-022561-rv5j1201	2545	10	cystic	cystic	JJ
cord-022561-rv5j1201	2545	11	,	,	,
cord-022561-rv5j1201	2545	12	and	and	CC
cord-022561-rv5j1201	2545	13	firm	firm	NN
cord-022561-rv5j1201	2545	14	;	;	:
cord-022561-rv5j1201	2545	15	some	some	DT
cord-022561-rv5j1201	2545	16	strains	strain	NNS
cord-022561-rv5j1201	2545	17	of	of	IN
cord-022561-rv5j1201	2545	18	virus	virus	NN
cord-022561-rv5j1201	2545	19	also	also	RB
cord-022561-rv5j1201	2545	20	cause	cause	VBP
cord-022561-rv5j1201	2545	21	nodal	nodal	JJ
cord-022561-rv5j1201	2545	22	hemorrhage	hemorrhage	NN
cord-022561-rv5j1201	2545	23	.	.	.
cord-022561-rv5j1201	2546	1	Microscopically	microscopically	RB
cord-022561-rv5j1201	2546	2	,	,	,
cord-022561-rv5j1201	2546	3	the	the	DT
cord-022561-rv5j1201	2546	4	lesions	lesion	NNS
cord-022561-rv5j1201	2546	5	in	in	IN
cord-022561-rv5j1201	2546	6	the	the	DT
cord-022561-rv5j1201	2546	7	lymph	lymph	NN
cord-022561-rv5j1201	2546	8	nodes	node	NNS
cord-022561-rv5j1201	2546	9	,	,	,
cord-022561-rv5j1201	2546	10	tonsils	tonsil	NNS
cord-022561-rv5j1201	2546	11	,	,	,
cord-022561-rv5j1201	2546	12	and	and	CC
cord-022561-rv5j1201	2546	13	spleens	spleen	NNS
cord-022561-rv5j1201	2546	14	consist	consist	VBP
cord-022561-rv5j1201	2546	15	of	of	IN
cord-022561-rv5j1201	2546	16	varying	vary	VBG
cord-022561-rv5j1201	2546	17	degrees	degree	NNS
cord-022561-rv5j1201	2546	18	of	of	IN
cord-022561-rv5j1201	2546	19	follicular	follicular	JJ
cord-022561-rv5j1201	2546	20	and	and	CC
cord-022561-rv5j1201	2546	21	paracortical	paracortical	JJ
cord-022561-rv5j1201	2546	22	hyperplasia	hyperplasia	NN
cord-022561-rv5j1201	2546	23	and	and	CC
cord-022561-rv5j1201	2546	24	lymphocyte	lymphocyte	NN
cord-022561-rv5j1201	2546	25	depletion	depletion	NN
cord-022561-rv5j1201	2546	26	in	in	IN
cord-022561-rv5j1201	2546	27	follicular	follicular	JJ
cord-022561-rv5j1201	2546	28	germinal	germinal	JJ
cord-022561-rv5j1201	2546	29	centers	center	NNS
cord-022561-rv5j1201	2546	30	.	.	.
cord-022561-rv5j1201	2547	1	Streptococcus	Streptococcus	NNP
cord-022561-rv5j1201	2547	2	porcinus	porcinus	NN
cord-022561-rv5j1201	2547	3	causes	cause	VBZ
cord-022561-rv5j1201	2547	4	jowl	jowl	NN
cord-022561-rv5j1201	2547	5	abscesses	abscess	NNS
cord-022561-rv5j1201	2547	6	in	in	IN
cord-022561-rv5j1201	2547	7	pigs	pig	NNS
cord-022561-rv5j1201	2547	8	.	.	.
cord-022561-rv5j1201	2548	1	The	the	DT
cord-022561-rv5j1201	2548	2	bacteria	bacteria	NNS
cord-022561-rv5j1201	2548	3	colonize	colonize	VBP
cord-022561-rv5j1201	2548	4	the	the	DT
cord-022561-rv5j1201	2548	5	oral	oral	JJ
cord-022561-rv5j1201	2548	6	cavity	cavity	NN
cord-022561-rv5j1201	2548	7	and	and	CC
cord-022561-rv5j1201	2548	8	spread	spread	VBD
cord-022561-rv5j1201	2548	9	to	to	TO
cord-022561-rv5j1201	2548	10	infect	infect	VB
cord-022561-rv5j1201	2548	11	tonsils	tonsil	NNS
cord-022561-rv5j1201	2548	12	and	and	CC
cord-022561-rv5j1201	2548	13	regional	regional	JJ
cord-022561-rv5j1201	2548	14	lymph	lymph	NN
cord-022561-rv5j1201	2548	15	nodes	node	NNS
cord-022561-rv5j1201	2548	16	.	.	.
cord-022561-rv5j1201	2549	1	The	the	DT
cord-022561-rv5j1201	2549	2	mandibular	mandibular	JJ
cord-022561-rv5j1201	2549	3	lymph	lymph	NN
cord-022561-rv5j1201	2549	4	nodes	node	NNS
cord-022561-rv5j1201	2549	5	are	be	VBP
cord-022561-rv5j1201	2549	6	the	the	DT
cord-022561-rv5j1201	2549	7	most	most	RBS
cord-022561-rv5j1201	2549	8	often	often	RB
cord-022561-rv5j1201	2549	9	affected	affect	VBN
cord-022561-rv5j1201	2549	10	and	and	CC
cord-022561-rv5j1201	2549	11	have	have	VBP
cord-022561-rv5j1201	2549	12	multiple	multiple	NN
cord-022561-rv5j1201	2549	13	,	,	,
cord-022561-rv5j1201	2549	14	1-to	1-to	JJ
cord-022561-rv5j1201	2549	15	10-cm	10-cm	CD
cord-022561-rv5j1201	2549	16	abscesses	abscess	NNS
cord-022561-rv5j1201	2549	17	;	;	:
cord-022561-rv5j1201	2549	18	the	the	DT
cord-022561-rv5j1201	2549	19	retropharyngeal	retropharyngeal	NN
cord-022561-rv5j1201	2549	20	and	and	CC
cord-022561-rv5j1201	2549	21	parotid	parotid	JJ
cord-022561-rv5j1201	2549	22	lymph	lymph	NN
cord-022561-rv5j1201	2549	23	nodes	node	NNS
cord-022561-rv5j1201	2549	24	may	may	MD
cord-022561-rv5j1201	2549	25	also	also	RB
cord-022561-rv5j1201	2549	26	be	be	VB
cord-022561-rv5j1201	2549	27	involved	involve	VBN
cord-022561-rv5j1201	2549	28	(	(	-LRB-
cord-022561-rv5j1201	2549	29	Fig	Fig	NNP
cord-022561-rv5j1201	2549	30	.	.	.
cord-022561-rv5j1201	2549	31	13	13	CD
cord-022561-rv5j1201	2549	32	-	-	SYM
cord-022561-rv5j1201	2549	33	89	89	CD
cord-022561-rv5j1201	2549	34	)	)	-RRB-
cord-022561-rv5j1201	2549	35	.	.	.
cord-022561-rv5j1201	2550	1	This	this	DT
cord-022561-rv5j1201	2550	2	once	once	RB
cord-022561-rv5j1201	2550	3	-	-	HYPH
cord-022561-rv5j1201	2550	4	prevalent	prevalent	JJ
cord-022561-rv5j1201	2550	5	disease	disease	NN
cord-022561-rv5j1201	2550	6	is	be	VBZ
cord-022561-rv5j1201	2550	7	now	now	RB
cord-022561-rv5j1201	2550	8	rare	rare	JJ
cord-022561-rv5j1201	2550	9	,	,	,
cord-022561-rv5j1201	2550	10	presumably	presumably	RB
cord-022561-rv5j1201	2550	11	due	due	IN
cord-022561-rv5j1201	2550	12	to	to	IN
cord-022561-rv5j1201	2550	13	improvements	improvement	NNS
cord-022561-rv5j1201	2550	14	in	in	IN
cord-022561-rv5j1201	2550	15	husbandry	husbandry	NN
cord-022561-rv5j1201	2550	16	,	,	,
cord-022561-rv5j1201	2550	17	feeder	feeder	NN
cord-022561-rv5j1201	2550	18	design	design	NN
cord-022561-rv5j1201	2550	19	,	,	,
cord-022561-rv5j1201	2550	20	and	and	CC
cord-022561-rv5j1201	2550	21	hygiene	hygiene	NN
cord-022561-rv5j1201	2550	22	.	.	.
cord-022561-rv5j1201	2551	1	It	-PRON-	PRP
cord-022561-rv5j1201	2551	2	is	be	VBZ
cord-022561-rv5j1201	2551	3	occasionally	occasionally	RB
cord-022561-rv5j1201	2551	4	isolated	isolate	VBN
cord-022561-rv5j1201	2551	5	in	in	IN
cord-022561-rv5j1201	2551	6	pigs	pig	NNS
cord-022561-rv5j1201	2551	7	with	with	IN
cord-022561-rv5j1201	2551	8	bacteremia	bacteremia	NN
cord-022561-rv5j1201	2551	9	.	.	.
cord-022561-rv5j1201	2552	1	disseminated	disseminate	VBN
cord-022561-rv5j1201	2552	2	histoplasmosis	histoplasmosis	NN
cord-022561-rv5j1201	2552	3	include	include	VBP
cord-022561-rv5j1201	2552	4	wasting	waste	VBG
cord-022561-rv5j1201	2552	5	,	,	,
cord-022561-rv5j1201	2552	6	emaciation	emaciation	NN
cord-022561-rv5j1201	2552	7	,	,	,
cord-022561-rv5j1201	2552	8	fever	fever	NN
cord-022561-rv5j1201	2552	9	,	,	,
cord-022561-rv5j1201	2552	10	respiratory	respiratory	JJ
cord-022561-rv5j1201	2552	11	distress	distress	NN
cord-022561-rv5j1201	2552	12	,	,	,
cord-022561-rv5j1201	2552	13	diarrhea	diarrhea	NN
cord-022561-rv5j1201	2552	14	with	with	IN
cord-022561-rv5j1201	2552	15	hematochezia	hematochezia	NNP
cord-022561-rv5j1201	2552	16	or	or	CC
cord-022561-rv5j1201	2552	17	melena	melena	NN
cord-022561-rv5j1201	2552	18	,	,	,
cord-022561-rv5j1201	2552	19	and	and	CC
cord-022561-rv5j1201	2552	20	lameness	lameness	NN
cord-022561-rv5j1201	2552	21	.	.	.
cord-022561-rv5j1201	2553	1	The	the	DT
cord-022561-rv5j1201	2553	2	clinicopathologic	clinicopathologic	JJ
cord-022561-rv5j1201	2553	3	changes	change	NNS
cord-022561-rv5j1201	2553	4	of	of	IN
cord-022561-rv5j1201	2553	5	disseminated	disseminate	VBN
cord-022561-rv5j1201	2553	6	histoplasmosis	histoplasmosis	NN
cord-022561-rv5j1201	2553	7	may	may	MD
cord-022561-rv5j1201	2553	8	include	include	VB
cord-022561-rv5j1201	2553	9	neutrophilia	neutrophilia	NNP
cord-022561-rv5j1201	2553	10	,	,	,
cord-022561-rv5j1201	2553	11	monocytosis	monocytosis	NNP
cord-022561-rv5j1201	2553	12	,	,	,
cord-022561-rv5j1201	2553	13	nonregenerative	nonregenerative	JJ
cord-022561-rv5j1201	2553	14	anemia	anemia	NN
cord-022561-rv5j1201	2553	15	in	in	IN
cord-022561-rv5j1201	2553	16	chronic	chronic	JJ
cord-022561-rv5j1201	2553	17	infections	infection	NNS
cord-022561-rv5j1201	2553	18	,	,	,
cord-022561-rv5j1201	2553	19	changes	change	NNS
cord-022561-rv5j1201	2553	20	in	in	IN
cord-022561-rv5j1201	2553	21	total	total	JJ
cord-022561-rv5j1201	2553	22	serum	serum	NN
cord-022561-rv5j1201	2553	23	protein	protein	NN
cord-022561-rv5j1201	2553	24	level	level	NN
cord-022561-rv5j1201	2553	25	,	,	,
cord-022561-rv5j1201	2553	26	and	and	CC
cord-022561-rv5j1201	2553	27	liver	liver	NN
cord-022561-rv5j1201	2553	28	enzyme	enzyme	NN
cord-022561-rv5j1201	2553	29	level	level	NN
cord-022561-rv5j1201	2553	30	elevations	elevation	NNS
cord-022561-rv5j1201	2553	31	with	with	IN
cord-022561-rv5j1201	2553	32	hepatic	hepatic	JJ
cord-022561-rv5j1201	2553	33	involvement	involvement	NN
cord-022561-rv5j1201	2553	34	.	.	.
cord-022561-rv5j1201	2554	1	The	the	DT
cord-022561-rv5j1201	2554	2	anemia	anemia	NN
cord-022561-rv5j1201	2554	3	is	be	VBZ
cord-022561-rv5j1201	2554	4	likely	likely	RB
cord-022561-rv5j1201	2554	5	a	a	DT
cord-022561-rv5j1201	2554	6	result	result	NN
cord-022561-rv5j1201	2554	7	of	of	IN
cord-022561-rv5j1201	2554	8	chronic	chronic	JJ
cord-022561-rv5j1201	2554	9	inflammation	inflammation	NN
cord-022561-rv5j1201	2554	10	,	,	,
cord-022561-rv5j1201	2554	11	Histoplasma	Histoplasma	NNP
cord-022561-rv5j1201	2554	12	infection	infection	NN
cord-022561-rv5j1201	2554	13	of	of	IN
cord-022561-rv5j1201	2554	14	the	the	DT
cord-022561-rv5j1201	2554	15	bone	bone	NN
cord-022561-rv5j1201	2554	16	marrow	marrow	NN
cord-022561-rv5j1201	2554	17	,	,	,
cord-022561-rv5j1201	2554	18	and/or	and/or	CC
cord-022561-rv5j1201	2554	19	intestinal	intestinal	JJ
cord-022561-rv5j1201	2554	20	blood	blood	NN
cord-022561-rv5j1201	2554	21	loss	loss	NN
cord-022561-rv5j1201	2554	22	in	in	IN
cord-022561-rv5j1201	2554	23	dogs	dog	NNS
cord-022561-rv5j1201	2554	24	with	with	IN
cord-022561-rv5j1201	2554	25	GI	GI	NNP
cord-022561-rv5j1201	2554	26	disease	disease	NN
cord-022561-rv5j1201	2554	27	.	.	.
cord-022561-rv5j1201	2555	1	Cytologic	cytologic	JJ
cord-022561-rv5j1201	2555	2	examination	examination	NN
cord-022561-rv5j1201	2555	3	is	be	VBZ
cord-022561-rv5j1201	2555	4	useful	useful	JJ
cord-022561-rv5j1201	2555	5	for	for	IN
cord-022561-rv5j1201	2555	6	the	the	DT
cord-022561-rv5j1201	2555	7	diagnosis	diagnosis	NN
cord-022561-rv5j1201	2555	8	of	of	IN
cord-022561-rv5j1201	2555	9	histoplasmosis	histoplasmosis	NN
cord-022561-rv5j1201	2556	1	(	(	-LRB-
cord-022561-rv5j1201	2556	2	tracheal	tracheal	JJ
cord-022561-rv5j1201	2556	3	wash	wash	NN
cord-022561-rv5j1201	2556	4	preparations	preparation	NNS
cord-022561-rv5j1201	2556	5	,	,	,
cord-022561-rv5j1201	2556	6	aspirates	aspirate	NNS
cord-022561-rv5j1201	2556	7	of	of	IN
cord-022561-rv5j1201	2556	8	bone	bone	NN
cord-022561-rv5j1201	2556	9	marrow	marrow	NN
cord-022561-rv5j1201	2556	10	and	and	CC
cord-022561-rv5j1201	2556	11	lymph	lymph	NN
cord-022561-rv5j1201	2556	12	nodes	node	NNS
cord-022561-rv5j1201	2556	13	)	)	-RRB-
cord-022561-rv5j1201	2556	14	,	,	,
cord-022561-rv5j1201	2556	15	where	where	WRB
cord-022561-rv5j1201	2556	16	organisms	organism	NNS
cord-022561-rv5j1201	2556	17	are	be	VBP
cord-022561-rv5j1201	2556	18	often	often	RB
cord-022561-rv5j1201	2556	19	visible	visible	JJ
cord-022561-rv5j1201	2556	20	in	in	IN
cord-022561-rv5j1201	2556	21	macrophages	macrophage	NNS
cord-022561-rv5j1201	2556	22	(	(	-LRB-
cord-022561-rv5j1201	2556	23	E-	E-	NNP
cord-022561-rv5j1201	2556	24	Fig	Fig	NNP
cord-022561-rv5j1201	2556	25	.	.	.
cord-022561-rv5j1201	2556	26	 	 	_SP
cord-022561-rv5j1201	2556	27	13	13	CD
cord-022561-rv5j1201	2556	28	-	-	SYM
cord-022561-rv5j1201	2556	29	15	15	CD
cord-022561-rv5j1201	2556	30	)	)	-RRB-
cord-022561-rv5j1201	2556	31	.	.	.
cord-022561-rv5j1201	2557	1	Grossly	grossly	RB
cord-022561-rv5j1201	2557	2	,	,	,
cord-022561-rv5j1201	2557	3	there	there	EX
cord-022561-rv5j1201	2557	4	is	be	VBZ
cord-022561-rv5j1201	2557	5	hepatosplenomegaly	hepatosplenomegaly	NNP
cord-022561-rv5j1201	2557	6	,	,	,
cord-022561-rv5j1201	2557	7	the	the	DT
cord-022561-rv5j1201	2557	8	intestines	intestine	NNS
cord-022561-rv5j1201	2557	9	are	be	VBP
cord-022561-rv5j1201	2557	10	thickened	thicken	VBN
cord-022561-rv5j1201	2557	11	and	and	CC
cord-022561-rv5j1201	2557	12	corrugated	corrugated	JJ
cord-022561-rv5j1201	2557	13	,	,	,
cord-022561-rv5j1201	2557	14	and	and	CC
cord-022561-rv5j1201	2557	15	the	the	DT
cord-022561-rv5j1201	2557	16	lymph	lymph	NN
cord-022561-rv5j1201	2557	17	nodes	node	NNS
cord-022561-rv5j1201	2557	18	are	be	VBP
cord-022561-rv5j1201	2557	19	uniformly	uniformly	RB
cord-022561-rv5j1201	2557	20	enlarged	enlarge	VBN
cord-022561-rv5j1201	2557	21	(	(	-LRB-
cord-022561-rv5j1201	2557	22	Fig	Fig	NNP
cord-022561-rv5j1201	2557	23	.	.	.
cord-022561-rv5j1201	2557	24	13	13	CD
cord-022561-rv5j1201	2557	25	-	-	SYM
cord-022561-rv5j1201	2557	26	91	91	CD
cord-022561-rv5j1201	2557	27	)	)	-RRB-
cord-022561-rv5j1201	2557	28	with	with	IN
cord-022561-rv5j1201	2557	29	loss	loss	NN
cord-022561-rv5j1201	2557	30	of	of	IN
cord-022561-rv5j1201	2557	31	normal	normal	JJ
cord-022561-rv5j1201	2557	32	architecture	architecture	NN
cord-022561-rv5j1201	2557	33	(	(	-LRB-
cord-022561-rv5j1201	2557	34	somewhat	somewhat	RB
cord-022561-rv5j1201	2557	35	similar	similar	JJ
cord-022561-rv5j1201	2557	36	to	to	IN
cord-022561-rv5j1201	2557	37	Siderofibrotic	Siderofibrotic	NNP
cord-022561-rv5j1201	2557	38	Plaques	Plaques	NNPS
cord-022561-rv5j1201	2557	39	,	,	,
cord-022561-rv5j1201	2557	40	Splenic	Splenic	NNP
cord-022561-rv5j1201	2557	41	Rupture	Rupture	NNP
cord-022561-rv5j1201	2557	42	,	,	,
cord-022561-rv5j1201	2557	43	and	and	CC
cord-022561-rv5j1201	2557	44	Accessory	accessory	JJ
cord-022561-rv5j1201	2557	45	Spleens	spleen	NNS
cord-022561-rv5j1201	2558	1	See	see	VB
cord-022561-rv5j1201	2558	2	the	the	DT
cord-022561-rv5j1201	2558	3	section	section	NN
cord-022561-rv5j1201	2558	4	on	on	IN
cord-022561-rv5j1201	2558	5	Miscellaneous	miscellaneous	JJ
cord-022561-rv5j1201	2558	6	Disorders	Disorders	NNPS
cord-022561-rv5j1201	2558	7	of	of	IN
cord-022561-rv5j1201	2558	8	the	the	DT
cord-022561-rv5j1201	2558	9	Spleen	Spleen	NNP
cord-022561-rv5j1201	2558	10	for	for	IN
cord-022561-rv5j1201	2558	11	discussions	discussion	NNS
cord-022561-rv5j1201	2558	12	on	on	IN
cord-022561-rv5j1201	2558	13	siderofibrotic	siderofibrotic	JJ
cord-022561-rv5j1201	2558	14	plaques	plaque	NNS
cord-022561-rv5j1201	2558	15	,	,	,
cord-022561-rv5j1201	2558	16	splenic	splenic	JJ
cord-022561-rv5j1201	2558	17	rupture	rupture	NN
cord-022561-rv5j1201	2558	18	,	,	,
cord-022561-rv5j1201	2558	19	and	and	CC
cord-022561-rv5j1201	2558	20	accessory	accessory	JJ
cord-022561-rv5j1201	2558	21	spleens	spleen	NNS
cord-022561-rv5j1201	2558	22	.	.	.
cord-022561-rv5j1201	2559	1	Splenic	splenic	JJ
cord-022561-rv5j1201	2559	2	nodular	nodular	JJ
cord-022561-rv5j1201	2559	3	hyperplasia	hyperplasia	NN
cord-022561-rv5j1201	2559	4	is	be	VBZ
cord-022561-rv5j1201	2559	5	common	common	JJ
cord-022561-rv5j1201	2559	6	in	in	IN
cord-022561-rv5j1201	2559	7	dogs	dog	NNS
cord-022561-rv5j1201	2559	8	and	and	CC
cord-022561-rv5j1201	2559	9	categorized	categorize	VBN
cord-022561-rv5j1201	2559	10	based	base	VBN
cord-022561-rv5j1201	2559	11	on	on	IN
cord-022561-rv5j1201	2559	12	their	-PRON-	PRP$
cord-022561-rv5j1201	2559	13	cellular	cellular	JJ
cord-022561-rv5j1201	2559	14	components	component	NNS
cord-022561-rv5j1201	2559	15	as	as	IN
cord-022561-rv5j1201	2559	16	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	2559	17	nodular	nodular	JJ
cord-022561-rv5j1201	2559	18	hyperplasia	hyperplasia	NN
cord-022561-rv5j1201	2559	19	or	or	CC
cord-022561-rv5j1201	2559	20	complex	complex	JJ
cord-022561-rv5j1201	2559	21	nodular	nodular	JJ
cord-022561-rv5j1201	2559	22	hyperplasia	hyperplasia	NN
cord-022561-rv5j1201	2559	23	.	.	.
cord-022561-rv5j1201	2560	1	Hematomas	Hematomas	NNP
cord-022561-rv5j1201	2560	2	may	may	MD
cord-022561-rv5j1201	2560	3	arise	arise	VB
cord-022561-rv5j1201	2560	4	within	within	IN
cord-022561-rv5j1201	2560	5	nodules	nodule	NNS
cord-022561-rv5j1201	2560	6	of	of	IN
cord-022561-rv5j1201	2560	7	hyperplasia	hyperplasia	NN
cord-022561-rv5j1201	2560	8	(	(	-LRB-
cord-022561-rv5j1201	2560	9	see	see	VB
cord-022561-rv5j1201	2560	10	Splenic	Splenic	NNP
cord-022561-rv5j1201	2560	11	Nodules	Nodules	NNPS
cord-022561-rv5j1201	2560	12	with	with	IN
cord-022561-rv5j1201	2560	13	a	a	DT
cord-022561-rv5j1201	2560	14	Bloody	Bloody	NNP
cord-022561-rv5j1201	2560	15	Consistency	Consistency	NNP
cord-022561-rv5j1201	2560	16	)	)	-RRB-
cord-022561-rv5j1201	2560	17	.	.	.
cord-022561-rv5j1201	2561	1	Lymphoid	lymphoid	JJ
cord-022561-rv5j1201	2561	2	(	(	-LRB-
cord-022561-rv5j1201	2561	3	or	or	CC
cord-022561-rv5j1201	2561	4	simple	simple	JJ
cord-022561-rv5j1201	2561	5	)	)	-RRB-
cord-022561-rv5j1201	2561	6	nodular	nodular	JJ
cord-022561-rv5j1201	2561	7	hyperplasia	hyperplasia	NN
cord-022561-rv5j1201	2561	8	consists	consist	VBZ
cord-022561-rv5j1201	2561	9	of	of	IN
cord-022561-rv5j1201	2561	10	a	a	DT
cord-022561-rv5j1201	2561	11	focal	focal	JJ
cord-022561-rv5j1201	2561	12	well	well	RB
cord-022561-rv5j1201	2561	13	-	-	HYPH
cord-022561-rv5j1201	2561	14	demarcated	demarcate	VBN
cord-022561-rv5j1201	2561	15	mass	mass	NN
cord-022561-rv5j1201	2561	16	composed	compose	VBN
cord-022561-rv5j1201	2561	17	of	of	IN
cord-022561-rv5j1201	2561	18	discrete	discrete	JJ
cord-022561-rv5j1201	2561	19	to	to	IN
cord-022561-rv5j1201	2561	20	coalescing	coalesce	VBG
cord-022561-rv5j1201	2561	21	aggregates	aggregate	NNS
cord-022561-rv5j1201	2561	22	of	of	IN
cord-022561-rv5j1201	2561	23	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	2561	24	.	.	.
cord-022561-rv5j1201	2562	1	The	the	DT
cord-022561-rv5j1201	2562	2	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	2562	3	may	may	MD
cord-022561-rv5j1201	2562	4	form	form	VB
cord-022561-rv5j1201	2562	5	follicular	follicular	JJ
cord-022561-rv5j1201	2562	6	structures	structure	NNS
cord-022561-rv5j1201	2562	7	with	with	IN
cord-022561-rv5j1201	2562	8	germinal	germinal	JJ
cord-022561-rv5j1201	2562	9	centers	center	NNS
cord-022561-rv5j1201	2562	10	and/or	and/or	CC
cord-022561-rv5j1201	2562	11	consist	consist	VBP
cord-022561-rv5j1201	2562	12	of	of	IN
cord-022561-rv5j1201	2562	13	a	a	DT
cord-022561-rv5j1201	2562	14	mixture	mixture	NN
cord-022561-rv5j1201	2562	15	of	of	IN
cord-022561-rv5j1201	2562	16	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	2562	17	with	with	IN
cord-022561-rv5j1201	2562	18	mantle	mantle	NN
cord-022561-rv5j1201	2562	19	and	and	CC
cord-022561-rv5j1201	2562	20	marginal	marginal	JJ
cord-022561-rv5j1201	2562	21	zone	zone	NN
cord-022561-rv5j1201	2562	22	cell	cell	NN
cord-022561-rv5j1201	2562	23	morphologic	morphologic	JJ
cord-022561-rv5j1201	2562	24	features	feature	NNS
cord-022561-rv5j1201	2562	25	.	.	.
cord-022561-rv5j1201	2563	1	The	the	DT
cord-022561-rv5j1201	2563	2	intervening	intervene	VBG
cord-022561-rv5j1201	2563	3	tissue	tissue	NN
cord-022561-rv5j1201	2563	4	is	be	VBZ
cord-022561-rv5j1201	2563	5	often	often	RB
cord-022561-rv5j1201	2563	6	congested	congested	JJ
cord-022561-rv5j1201	2563	7	and	and	CC
cord-022561-rv5j1201	2563	8	may	may	MD
cord-022561-rv5j1201	2563	9	contain	contain	VB
cord-022561-rv5j1201	2563	10	plasma	plasma	NN
cord-022561-rv5j1201	2563	11	cells	cell	NNS
cord-022561-rv5j1201	2563	12	,	,	,
cord-022561-rv5j1201	2563	13	but	but	CC
cord-022561-rv5j1201	2563	14	stroma	stroma	NN
cord-022561-rv5j1201	2563	15	is	be	VBZ
cord-022561-rv5j1201	2563	16	not	not	RB
cord-022561-rv5j1201	2563	17	observed	observe	VBN
cord-022561-rv5j1201	2563	18	(	(	-LRB-
cord-022561-rv5j1201	2563	19	Fig	Fig	NNP
cord-022561-rv5j1201	2563	20	.	.	NNP
cord-022561-rv5j1201	2563	21	13	13	CD
cord-022561-rv5j1201	2563	22	-	-	SYM
cord-022561-rv5j1201	2563	23	90	90	CD
cord-022561-rv5j1201	2563	24	;	;	:
cord-022561-rv5j1201	2563	25	E	E	NNP
cord-022561-rv5j1201	2563	26	-	-	HYPH
cord-022561-rv5j1201	2563	27	Fig	fig	NN
cord-022561-rv5j1201	2563	28	.	.	.
cord-022561-rv5j1201	2564	1	13	13	CD
cord-022561-rv5j1201	2564	2	-	-	SYM
cord-022561-rv5j1201	2564	3	13	13	CD
cord-022561-rv5j1201	2564	4	)	)	-RRB-
cord-022561-rv5j1201	2564	5	.	.	.
cord-022561-rv5j1201	2565	1	Complex	complex	JJ
cord-022561-rv5j1201	2565	2	nodular	nodular	JJ
cord-022561-rv5j1201	2565	3	hyperplasia	hyperplasia	NN
cord-022561-rv5j1201	2565	4	is	be	VBZ
cord-022561-rv5j1201	2565	5	a	a	DT
cord-022561-rv5j1201	2565	6	focal	focal	JJ
cord-022561-rv5j1201	2565	7	mass	mass	NN
cord-022561-rv5j1201	2565	8	that	that	WDT
cord-022561-rv5j1201	2565	9	contains	contain	VBZ
cord-022561-rv5j1201	2565	10	two	two	CD
cord-022561-rv5j1201	2565	11	proliferative	proliferative	JJ
cord-022561-rv5j1201	2565	12	components	component	NNS
cord-022561-rv5j1201	2565	13	:	:	:
cord-022561-rv5j1201	2565	14	lymphoid	lymphoid	NN
cord-022561-rv5j1201	2565	15	and	and	CC
cord-022561-rv5j1201	2565	16	stroma	stroma	NN
cord-022561-rv5j1201	2565	17	(	(	-LRB-
cord-022561-rv5j1201	2565	18	E-	E-	NNP
cord-022561-rv5j1201	2565	19	Fig	Fig	NNP
cord-022561-rv5j1201	2565	20	.	.	.
cord-022561-rv5j1201	2565	21	13	13	CD
cord-022561-rv5j1201	2565	22	-	-	SYM
cord-022561-rv5j1201	2565	23	14	14	CD
cord-022561-rv5j1201	2565	24	)	)	-RRB-
cord-022561-rv5j1201	2565	25	.	.	.
cord-022561-rv5j1201	2566	1	The	the	DT
cord-022561-rv5j1201	2566	2	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	2566	3	component	component	NN
cord-022561-rv5j1201	2566	4	resembles	resemble	VBZ
cord-022561-rv5j1201	2566	5	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	2566	6	nodular	nodular	JJ
cord-022561-rv5j1201	2566	7	hyperplasia	hyperplasia	NN
cord-022561-rv5j1201	2566	8	described	describe	VBN
cord-022561-rv5j1201	2566	9	above	above	RB
cord-022561-rv5j1201	2566	10	.	.	.
cord-022561-rv5j1201	2567	1	There	there	EX
cord-022561-rv5j1201	2567	2	is	be	VBZ
cord-022561-rv5j1201	2567	3	proliferation	proliferation	NN
cord-022561-rv5j1201	2567	4	of	of	IN
cord-022561-rv5j1201	2567	5	the	the	DT
cord-022561-rv5j1201	2567	6	intervening	intervene	VBG
cord-022561-rv5j1201	2567	7	stromal	stromal	JJ
cord-022561-rv5j1201	2567	8	tissues	tissue	NNS
cord-022561-rv5j1201	2567	9	with	with	IN
cord-022561-rv5j1201	2567	10	fibroplasia	fibroplasia	NNP
cord-022561-rv5j1201	2567	11	,	,	,
cord-022561-rv5j1201	2567	12	smooth	smooth	JJ
cord-022561-rv5j1201	2567	13	muscle	muscle	NN
cord-022561-rv5j1201	2567	14	hyperplasia	hyperplasia	NN
cord-022561-rv5j1201	2567	15	,	,	,
cord-022561-rv5j1201	2567	16	and	and	CC
cord-022561-rv5j1201	2567	17	histiocytic	histiocytic	JJ
cord-022561-rv5j1201	2567	18	hyperplasia	hyperplasia	NN
cord-022561-rv5j1201	2567	19	;	;	:
cord-022561-rv5j1201	2567	20	EMH	EMH	NNP
cord-022561-rv5j1201	2567	21	and	and	CC
cord-022561-rv5j1201	2567	22	plasma	plasma	NN
cord-022561-rv5j1201	2567	23	cells	cell	NNS
cord-022561-rv5j1201	2567	24	may	may	MD
cord-022561-rv5j1201	2567	25	also	also	RB
cord-022561-rv5j1201	2567	26	be	be	VB
cord-022561-rv5j1201	2567	27	present	present	JJ
cord-022561-rv5j1201	2567	28	.	.	.
cord-022561-rv5j1201	2568	1	It	-PRON-	PRP
cord-022561-rv5j1201	2568	2	has	have	VBZ
cord-022561-rv5j1201	2568	3	recently	recently	RB
cord-022561-rv5j1201	2568	4	come	come	VBN
cord-022561-rv5j1201	2568	5	to	to	TO
cord-022561-rv5j1201	2568	6	light	light	VB
cord-022561-rv5j1201	2568	7	that	that	IN
cord-022561-rv5j1201	2568	8	the	the	DT
cord-022561-rv5j1201	2568	9	entity	entity	NN
cord-022561-rv5j1201	2568	10	splenic	splenic	JJ
cord-022561-rv5j1201	2568	11	fibrohistiocytic	fibrohistiocytic	JJ
cord-022561-rv5j1201	2568	12	nodule	nodule	NN
cord-022561-rv5j1201	2568	13	(	(	-LRB-
cord-022561-rv5j1201	2568	14	SFHN	SFHN	NNP
cord-022561-rv5j1201	2568	15	)	)	-RRB-
cord-022561-rv5j1201	2568	16	,	,	,
cord-022561-rv5j1201	2568	17	first	first	RB
cord-022561-rv5j1201	2568	18	described	describe	VBN
cord-022561-rv5j1201	2568	19	in	in	IN
cord-022561-rv5j1201	2568	20	1998	1998	CD
cord-022561-rv5j1201	2568	21	,	,	,
cord-022561-rv5j1201	2568	22	is	be	VBZ
cord-022561-rv5j1201	2568	23	not	not	RB
cord-022561-rv5j1201	2568	24	a	a	DT
cord-022561-rv5j1201	2568	25	single	single	JJ
cord-022561-rv5j1201	2568	26	condition	condition	NN
cord-022561-rv5j1201	2568	27	,	,	,
cord-022561-rv5j1201	2568	28	but	but	CC
cord-022561-rv5j1201	2568	29	in	in	IN
cord-022561-rv5j1201	2568	30	fact	fact	NN
cord-022561-rv5j1201	2568	31	a	a	DT
cord-022561-rv5j1201	2568	32	complex	complex	JJ
cord-022561-rv5j1201	2568	33	group	group	NN
cord-022561-rv5j1201	2568	34	of	of	IN
cord-022561-rv5j1201	2568	35	diseases	disease	NNS
cord-022561-rv5j1201	2568	36	.	.	.
cord-022561-rv5j1201	2569	1	Our	-PRON-	PRP$
cord-022561-rv5j1201	2569	2	better	well	JJR
cord-022561-rv5j1201	2569	3	understanding	understanding	NN
cord-022561-rv5j1201	2569	4	of	of	IN
cord-022561-rv5j1201	2569	5	the	the	DT
cord-022561-rv5j1201	2569	6	spectrum	spectrum	NN
cord-022561-rv5j1201	2569	7	of	of	IN
cord-022561-rv5j1201	2569	8	diseases	disease	NNS
cord-022561-rv5j1201	2569	9	once	once	RB
cord-022561-rv5j1201	2569	10	described	describe	VBN
cord-022561-rv5j1201	2569	11	under	under	IN
cord-022561-rv5j1201	2569	12	the	the	DT
cord-022561-rv5j1201	2569	13	term	term	NN
cord-022561-rv5j1201	2569	14	splenic	splenic	JJ
cord-022561-rv5j1201	2569	15	fibrohistiocytic	fibrohistiocytic	JJ
cord-022561-rv5j1201	2569	16	nodule	nodule	NN
cord-022561-rv5j1201	2569	17	is	be	VBZ
cord-022561-rv5j1201	2569	18	due	due	JJ
cord-022561-rv5j1201	2569	19	to	to	IN
cord-022561-rv5j1201	2569	20	increasing	increase	VBG
cord-022561-rv5j1201	2569	21	knowledge	knowledge	NN
cord-022561-rv5j1201	2569	22	of	of	IN
cord-022561-rv5j1201	2569	23	histiocytic	histiocytic	JJ
cord-022561-rv5j1201	2569	24	disorders	disorder	NNS
cord-022561-rv5j1201	2569	25	and	and	CC
cord-022561-rv5j1201	2569	26	immunochemistry	immunochemistry	NN
cord-022561-rv5j1201	2569	27	.	.	.
cord-022561-rv5j1201	2570	1	The	the	DT
cord-022561-rv5j1201	2570	2	original	original	JJ
cord-022561-rv5j1201	2570	3	definition	definition	NN
cord-022561-rv5j1201	2570	4	of	of	IN
cord-022561-rv5j1201	2570	5	splenic	splenic	JJ
cord-022561-rv5j1201	2570	6	fibrohistiocytic	fibrohistiocytic	JJ
cord-022561-rv5j1201	2570	7	nodule	nodule	NN
cord-022561-rv5j1201	2570	8	is	be	VBZ
cord-022561-rv5j1201	2570	9	a	a	DT
cord-022561-rv5j1201	2570	10	nodule	nodule	NN
cord-022561-rv5j1201	2570	11	characterized	characterize	VBN
cord-022561-rv5j1201	2570	12	by	by	IN
cord-022561-rv5j1201	2570	13	a	a	DT
cord-022561-rv5j1201	2570	14	stromal	stromal	JJ
cord-022561-rv5j1201	2570	15	population	population	NN
cord-022561-rv5j1201	2570	16	of	of	IN
cord-022561-rv5j1201	2570	17	histiocytoid	histiocytoid	NNP
cord-022561-rv5j1201	2570	18	and	and	CC
cord-022561-rv5j1201	2570	19	spindle	spindle	NN
cord-022561-rv5j1201	2570	20	cells	cell	NNS
cord-022561-rv5j1201	2570	21	intermixed	intermix	VBN
cord-022561-rv5j1201	2570	22	with	with	IN
cord-022561-rv5j1201	2570	23	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	2570	24	.	.	.
cord-022561-rv5j1201	2571	1	Grading	grading	NN
cord-022561-rv5j1201	2571	2	was	be	VBD
cord-022561-rv5j1201	2571	3	based	base	VBN
cord-022561-rv5j1201	2571	4	on	on	IN
cord-022561-rv5j1201	2571	5	the	the	DT
cord-022561-rv5j1201	2571	6	lymphocyte	lymphocyte	NN
cord-022561-rv5j1201	2571	7	percentage	percentage	NN
cord-022561-rv5j1201	2571	8	of	of	IN
cord-022561-rv5j1201	2571	9	the	the	DT
cord-022561-rv5j1201	2571	10	population	population	NN
cord-022561-rv5j1201	2571	11	(	(	-LRB-
cord-022561-rv5j1201	2571	12	e.g.	e.g.	RB
cord-022561-rv5j1201	2571	13	,	,	,
cord-022561-rv5j1201	2571	14	>	>	XX
cord-022561-rv5j1201	2571	15	70	70	CD
cord-022561-rv5j1201	2571	16	%	%	NN
cord-022561-rv5j1201	2571	17	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	2571	18	=	=	NFP
cord-022561-rv5j1201	2572	1	grade	grade	NN
cord-022561-rv5j1201	2572	2	1	1	CD
cord-022561-rv5j1201	2572	3	;	;	:
cord-022561-rv5j1201	2572	4	<	<	XX
cord-022561-rv5j1201	2572	5	40	40	CD
cord-022561-rv5j1201	2572	6	%	%	NN
cord-022561-rv5j1201	2572	7	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	2572	8	=	=	SYM
cord-022561-rv5j1201	2572	9	grade	grade	NN
cord-022561-rv5j1201	2572	10	3	3	CD
cord-022561-rv5j1201	2572	11	)	)	-RRB-
cord-022561-rv5j1201	2572	12	;	;	:
cord-022561-rv5j1201	2573	1	dogs	dog	NNS
cord-022561-rv5j1201	2573	2	with	with	IN
cord-022561-rv5j1201	2573	3	grade	grade	NN
cord-022561-rv5j1201	2573	4	1	1	CD
cord-022561-rv5j1201	2573	5	splenic	splenic	JJ
cord-022561-rv5j1201	2573	6	fibrohistiocytic	fibrohistiocytic	JJ
cord-022561-rv5j1201	2573	7	nodule	nodule	NN
cord-022561-rv5j1201	2573	8	had	have	VBD
cord-022561-rv5j1201	2573	9	a	a	DT
cord-022561-rv5j1201	2573	10	much	much	RB
cord-022561-rv5j1201	2573	11	better	well	JJR
cord-022561-rv5j1201	2573	12	1-year	1-year	CD
cord-022561-rv5j1201	2573	13	survival	survival	NN
cord-022561-rv5j1201	2573	14	rate	rate	NN
cord-022561-rv5j1201	2573	15	,	,	,
cord-022561-rv5j1201	2573	16	and	and	CC
cord-022561-rv5j1201	2573	17	dogs	dog	NNS
cord-022561-rv5j1201	2573	18	with	with	IN
cord-022561-rv5j1201	2573	19	grade	grade	NN
cord-022561-rv5j1201	2573	20	3	3	CD
cord-022561-rv5j1201	2573	21	nodules	nodule	NNS
cord-022561-rv5j1201	2573	22	may	may	MD
cord-022561-rv5j1201	2573	23	develop	develop	VB
cord-022561-rv5j1201	2573	24	sarcomas	sarcoma	NNS
cord-022561-rv5j1201	2573	25	(	(	-LRB-
cord-022561-rv5j1201	2573	26	often	often	RB
cord-022561-rv5j1201	2573	27	malignant	malignant	JJ
cord-022561-rv5j1201	2573	28	fibrous	fibrous	JJ
cord-022561-rv5j1201	2573	29	histiocytoma	histiocytoma	NN
cord-022561-rv5j1201	2573	30	,	,	,
cord-022561-rv5j1201	2573	31	a	a	DT
cord-022561-rv5j1201	2573	32	now	now	RB
cord-022561-rv5j1201	2573	33	outdated	outdated	JJ
cord-022561-rv5j1201	2573	34	term	term	NN
cord-022561-rv5j1201	2573	35	)	)	-RRB-
cord-022561-rv5j1201	2573	36	.	.	.
cord-022561-rv5j1201	2574	1	With	with	IN
cord-022561-rv5j1201	2574	2	our	-PRON-	PRP$
cord-022561-rv5j1201	2574	3	increasing	increase	VBG
cord-022561-rv5j1201	2574	4	knowledge	knowledge	NN
cord-022561-rv5j1201	2574	5	of	of	IN
cord-022561-rv5j1201	2574	6	histiocytic	histiocytic	JJ
cord-022561-rv5j1201	2574	7	disorders	disorder	NNS
cord-022561-rv5j1201	2574	8	and	and	CC
cord-022561-rv5j1201	2574	9	additional	additional	JJ
cord-022561-rv5j1201	2574	10	immunohistochemical	immunohistochemical	JJ
cord-022561-rv5j1201	2574	11	stains	stain	NNS
cord-022561-rv5j1201	2574	12	,	,	,
cord-022561-rv5j1201	2574	13	diseases	disease	NNS
cord-022561-rv5j1201	2574	14	that	that	WDT
cord-022561-rv5j1201	2574	15	likely	likely	RB
cord-022561-rv5j1201	2574	16	were	be	VBD
cord-022561-rv5j1201	2574	17	encompassed	encompass	VBN
cord-022561-rv5j1201	2574	18	by	by	IN
cord-022561-rv5j1201	2574	19	the	the	DT
cord-022561-rv5j1201	2574	20	term	term	NN
cord-022561-rv5j1201	2574	21	splenic	splenic	JJ
cord-022561-rv5j1201	2574	22	fibrohistiocytic	fibrohistiocytic	JJ
cord-022561-rv5j1201	2574	23	nodule	nodule	NN
cord-022561-rv5j1201	2574	24	include	include	VBP
cord-022561-rv5j1201	2574	25	the	the	DT
cord-022561-rv5j1201	2574	26	following	follow	VBG
cord-022561-rv5j1201	2574	27	:	:	:
cord-022561-rv5j1201	2574	28	complex	complex	JJ
cord-022561-rv5j1201	2574	29	and	and	CC
cord-022561-rv5j1201	2574	30	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	2574	31	nodular	nodular	JJ
cord-022561-rv5j1201	2574	32	hyperplasia	hyperplasia	NN
cord-022561-rv5j1201	2574	33	(	(	-LRB-
cord-022561-rv5j1201	2574	34	see	see	VB
cord-022561-rv5j1201	2574	35	earlier	early	RBR
cord-022561-rv5j1201	2574	36	)	)	-RRB-
cord-022561-rv5j1201	2574	37	,	,	,
cord-022561-rv5j1201	2574	38	stromal	stromal	JJ
cord-022561-rv5j1201	2574	39	sarcoma	sarcoma	NN
cord-022561-rv5j1201	2574	40	,	,	,
cord-022561-rv5j1201	2574	41	histiocytic	histiocytic	JJ
cord-022561-rv5j1201	2574	42	sarcoma	sarcoma	NN
cord-022561-rv5j1201	2574	43	,	,	,
cord-022561-rv5j1201	2574	44	marginal	marginal	JJ
cord-022561-rv5j1201	2574	45	zone	zone	NN
cord-022561-rv5j1201	2574	46	hyperplasia	hyperplasia	NN
cord-022561-rv5j1201	2574	47	,	,	,
cord-022561-rv5j1201	2574	48	marginal	marginal	JJ
cord-022561-rv5j1201	2574	49	zone	zone	NN
cord-022561-rv5j1201	2574	50	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2574	51	,	,	,
cord-022561-rv5j1201	2574	52	and	and	CC
cord-022561-rv5j1201	2574	53	diffuse	diffuse	VB
cord-022561-rv5j1201	2574	54	large	large	JJ
cord-022561-rv5j1201	2574	55	B	b	NN
cord-022561-rv5j1201	2574	56	cell	cell	NN
cord-022561-rv5j1201	2574	57	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2574	58	(	(	-LRB-
cord-022561-rv5j1201	2574	59	see	see	VB
cord-022561-rv5j1201	2574	60	Lymphoid	Lymphoid	NNP
cord-022561-rv5j1201	2574	61	/	/	SYM
cord-022561-rv5j1201	2574	62	Lymphatic	Lymphatic	NNP
cord-022561-rv5j1201	2574	63	System	System	NNP
cord-022561-rv5j1201	2574	64	,	,	,
cord-022561-rv5j1201	2574	65	Disorders	disorder	NNS
cord-022561-rv5j1201	2574	66	of	of	IN
cord-022561-rv5j1201	2574	67	Domestic	domestic	JJ
cord-022561-rv5j1201	2574	68	Animals	animal	NNS
cord-022561-rv5j1201	2574	69	:	:	:
cord-022561-rv5j1201	2574	70	Lymph	lymph	NN
cord-022561-rv5j1201	2574	71	Nodes	node	NNS
cord-022561-rv5j1201	2574	72	,	,	,
cord-022561-rv5j1201	2574	73	Neoplasia	neoplasia	NN
cord-022561-rv5j1201	2574	74	,	,	,
cord-022561-rv5j1201	2574	75	Lymphoma	Lymphoma	NNP
cord-022561-rv5j1201	2574	76	)	)	-RRB-
cord-022561-rv5j1201	2574	77	.	.	.
cord-022561-rv5j1201	2575	1	Histoplasma	Histoplasma	NNP
cord-022561-rv5j1201	2575	2	capsulatum	capsulatum	NN
cord-022561-rv5j1201	2575	3	can	can	MD
cord-022561-rv5j1201	2575	4	cause	cause	VB
cord-022561-rv5j1201	2575	5	a	a	DT
cord-022561-rv5j1201	2575	6	disseminated	disseminate	VBN
cord-022561-rv5j1201	2575	7	fungal	fungal	JJ
cord-022561-rv5j1201	2575	8	disease	disease	NN
cord-022561-rv5j1201	2575	9	that	that	WDT
cord-022561-rv5j1201	2575	10	is	be	VBZ
cord-022561-rv5j1201	2575	11	widely	widely	RB
cord-022561-rv5j1201	2575	12	endemic	endemic	JJ
cord-022561-rv5j1201	2575	13	,	,	,
cord-022561-rv5j1201	2575	14	particularly	particularly	RB
cord-022561-rv5j1201	2575	15	in	in	IN
cord-022561-rv5j1201	2575	16	areas	area	NNS
cord-022561-rv5j1201	2575	17	with	with	IN
cord-022561-rv5j1201	2575	18	major	major	JJ
cord-022561-rv5j1201	2575	19	river	river	NN
cord-022561-rv5j1201	2575	20	valleys	valley	NNS
cord-022561-rv5j1201	2575	21	and	and	CC
cord-022561-rv5j1201	2575	22	temperate	temperate	JJ
cord-022561-rv5j1201	2575	23	or	or	CC
cord-022561-rv5j1201	2575	24	tropical	tropical	JJ
cord-022561-rv5j1201	2575	25	climates	climate	NNS
cord-022561-rv5j1201	2575	26	(	(	-LRB-
cord-022561-rv5j1201	2575	27	e.g.	e.g.	RB
cord-022561-rv5j1201	2575	28	,	,	,
cord-022561-rv5j1201	2575	29	midwestern	midwestern	JJ
cord-022561-rv5j1201	2575	30	and	and	CC
cord-022561-rv5j1201	2575	31	southern	southern	JJ
cord-022561-rv5j1201	2575	32	United	United	NNP
cord-022561-rv5j1201	2575	33	States	States	NNP
cord-022561-rv5j1201	2575	34	)	)	-RRB-
cord-022561-rv5j1201	2575	35	.	.	.
cord-022561-rv5j1201	2576	1	Free	free	JJ
cord-022561-rv5j1201	2576	2	-	-	HYPH
cord-022561-rv5j1201	2576	3	living	live	VBG
cord-022561-rv5j1201	2576	4	organisms	organism	NNS
cord-022561-rv5j1201	2576	5	in	in	IN
cord-022561-rv5j1201	2576	6	the	the	DT
cord-022561-rv5j1201	2576	7	mycelial	mycelial	JJ
cord-022561-rv5j1201	2576	8	phase	phase	NN
cord-022561-rv5j1201	2576	9	produce	produce	VBP
cord-022561-rv5j1201	2576	10	macroconidia	macroconidia	NNS
cord-022561-rv5j1201	2576	11	and	and	CC
cord-022561-rv5j1201	2576	12	microconidia	microconidia	NNP
cord-022561-rv5j1201	2576	13	that	that	WDT
cord-022561-rv5j1201	2576	14	are	be	VBP
cord-022561-rv5j1201	2576	15	inhaled	inhale	VBN
cord-022561-rv5j1201	2576	16	and	and	CC
cord-022561-rv5j1201	2576	17	converted	convert	VBN
cord-022561-rv5j1201	2576	18	to	to	IN
cord-022561-rv5j1201	2576	19	the	the	DT
cord-022561-rv5j1201	2576	20	yeast	yeast	NN
cord-022561-rv5j1201	2576	21	phase	phase	NN
cord-022561-rv5j1201	2576	22	in	in	IN
cord-022561-rv5j1201	2576	23	the	the	DT
cord-022561-rv5j1201	2576	24	lung	lung	NN
cord-022561-rv5j1201	2576	25	.	.	.
cord-022561-rv5j1201	2577	1	Yeasts	yeast	NNS
cord-022561-rv5j1201	2577	2	are	be	VBP
cord-022561-rv5j1201	2577	3	phagocytized	phagocytize	VBN
cord-022561-rv5j1201	2577	4	and	and	CC
cord-022561-rv5j1201	2577	5	harbored	harbor	VBN
cord-022561-rv5j1201	2577	6	by	by	IN
cord-022561-rv5j1201	2577	7	macrophages	macrophage	NNS
cord-022561-rv5j1201	2577	8	of	of	IN
cord-022561-rv5j1201	2577	9	the	the	DT
cord-022561-rv5j1201	2577	10	monocyte	monocyte	JJ
cord-022561-rv5j1201	2577	11	-	-	HYPH
cord-022561-rv5j1201	2577	12	macrophage	macrophage	NN
cord-022561-rv5j1201	2577	13	system	system	NN
cord-022561-rv5j1201	2577	14	.	.	.
cord-022561-rv5j1201	2578	1	In	in	IN
cord-022561-rv5j1201	2578	2	some	some	DT
cord-022561-rv5j1201	2578	3	dogs	dog	NNS
cord-022561-rv5j1201	2578	4	the	the	DT
cord-022561-rv5j1201	2578	5	disease	disease	NN
cord-022561-rv5j1201	2578	6	is	be	VBZ
cord-022561-rv5j1201	2578	7	limited	limit	VBN
cord-022561-rv5j1201	2578	8	to	to	IN
cord-022561-rv5j1201	2578	9	the	the	DT
cord-022561-rv5j1201	2578	10	respiratory	respiratory	JJ
cord-022561-rv5j1201	2578	11	tract	tract	NN
cord-022561-rv5j1201	2578	12	and	and	CC
cord-022561-rv5j1201	2578	13	causes	cause	NNS
cord-022561-rv5j1201	2578	14	dyspnea	dyspnea	NN
cord-022561-rv5j1201	2578	15	and	and	CC
cord-022561-rv5j1201	2578	16	coughing	coughing	NN
cord-022561-rv5j1201	2578	17	.	.	.
cord-022561-rv5j1201	2579	1	However	however	RB
cord-022561-rv5j1201	2579	2	,	,	,
cord-022561-rv5j1201	2579	3	in	in	IN
cord-022561-rv5j1201	2579	4	most	most	JJS
cord-022561-rv5j1201	2579	5	dogs	dog	NNS
cord-022561-rv5j1201	2579	6	,	,	,
cord-022561-rv5j1201	2579	7	the	the	DT
cord-022561-rv5j1201	2579	8	disease	disease	NN
cord-022561-rv5j1201	2579	9	is	be	VBZ
cord-022561-rv5j1201	2579	10	disseminated	disseminate	VBN
cord-022561-rv5j1201	2579	11	throughout	throughout	IN
cord-022561-rv5j1201	2579	12	the	the	DT
cord-022561-rv5j1201	2579	13	body	body	NN
cord-022561-rv5j1201	2579	14	,	,	,
cord-022561-rv5j1201	2579	15	predominantly	predominantly	RB
cord-022561-rv5j1201	2579	16	affecting	affect	VBG
cord-022561-rv5j1201	2579	17	the	the	DT
cord-022561-rv5j1201	2579	18	liver	liver	NN
cord-022561-rv5j1201	2579	19	,	,	,
cord-022561-rv5j1201	2579	20	spleen	spleen	NNS
cord-022561-rv5j1201	2579	21	,	,	,
cord-022561-rv5j1201	2579	22	gastrointestinal	gastrointestinal	JJ
cord-022561-rv5j1201	2579	23	tract	tract	NN
cord-022561-rv5j1201	2579	24	,	,	,
cord-022561-rv5j1201	2579	25	bone	bone	NN
cord-022561-rv5j1201	2579	26	marrow	marrow	NN
cord-022561-rv5j1201	2579	27	,	,	,
cord-022561-rv5j1201	2579	28	skin	skin	NN
cord-022561-rv5j1201	2579	29	,	,	,
cord-022561-rv5j1201	2579	30	and	and	CC
cord-022561-rv5j1201	2579	31	eyes	eye	NNS
cord-022561-rv5j1201	2579	32	;	;	:
cord-022561-rv5j1201	2579	33	primary	primary	JJ
cord-022561-rv5j1201	2579	34	gastrointestinal	gastrointestinal	JJ
cord-022561-rv5j1201	2579	35	disease	disease	NN
cord-022561-rv5j1201	2579	36	is	be	VBZ
cord-022561-rv5j1201	2579	37	also	also	RB
cord-022561-rv5j1201	2579	38	reported	report	VBN
cord-022561-rv5j1201	2579	39	.	.	.
cord-022561-rv5j1201	2580	1	The	the	DT
cord-022561-rv5j1201	2580	2	clinical	clinical	JJ
cord-022561-rv5j1201	2580	3	signs	sign	NNS
cord-022561-rv5j1201	2580	4	in	in	IN
cord-022561-rv5j1201	2580	5	cases	case	NNS
cord-022561-rv5j1201	2580	6	of	of	IN
cord-022561-rv5j1201	2580	7	and	and	CC
cord-022561-rv5j1201	2580	8	hepatosplenomegaly	hepatosplenomegaly	NNP
cord-022561-rv5j1201	2580	9	(	(	-LRB-
cord-022561-rv5j1201	2580	10	E-	E-	NNP
cord-022561-rv5j1201	2580	11	Fig	Fig	NNP
cord-022561-rv5j1201	2580	12	.	.	.
cord-022561-rv5j1201	2581	1	13	13	CD
cord-022561-rv5j1201	2581	2	-	-	SYM
cord-022561-rv5j1201	2581	3	16	16	CD
cord-022561-rv5j1201	2581	4	)	)	-RRB-
cord-022561-rv5j1201	2581	5	.	.	.
cord-022561-rv5j1201	2582	1	Histologically	histologically	RB
cord-022561-rv5j1201	2582	2	,	,	,
cord-022561-rv5j1201	2582	3	the	the	DT
cord-022561-rv5j1201	2582	4	lymph	lymph	NN
cord-022561-rv5j1201	2582	5	node	node	NN
cord-022561-rv5j1201	2582	6	sinuses	sinus	NNS
cord-022561-rv5j1201	2582	7	and	and	CC
cord-022561-rv5j1201	2582	8	splenic	splenic	JJ
cord-022561-rv5j1201	2582	9	red	red	JJ
cord-022561-rv5j1201	2582	10	pulp	pulp	NN
cord-022561-rv5j1201	2582	11	are	be	VBP
cord-022561-rv5j1201	2582	12	filled	fill	VBN
cord-022561-rv5j1201	2582	13	with	with	IN
cord-022561-rv5j1201	2582	14	macrophages	macrophage	NNS
cord-022561-rv5j1201	2582	15	that	that	WDT
cord-022561-rv5j1201	2582	16	contain	contain	VBP
cord-022561-rv5j1201	2582	17	intracytoplasmic	intracytoplasmic	JJ
cord-022561-rv5j1201	2582	18	,	,	,
cord-022561-rv5j1201	2582	19	round	round	JJ
cord-022561-rv5j1201	2582	20	,	,	,
cord-022561-rv5j1201	2582	21	2-µm	2-µm	CD
cord-022561-rv5j1201	2582	22	-	-	HYPH
cord-022561-rv5j1201	2582	23	diameter	diameter	NN
cord-022561-rv5j1201	2582	24	organisms	organism	NNS
cord-022561-rv5j1201	2582	25	with	with	IN
cord-022561-rv5j1201	2582	26	a	a	DT
cord-022561-rv5j1201	2582	27	small	small	JJ
cord-022561-rv5j1201	2582	28	kinetoplast	kinetoplast	NN
cord-022561-rv5j1201	2582	29	.	.	.
cord-022561-rv5j1201	2583	1	Though	though	IN
cord-022561-rv5j1201	2583	2	there	there	EX
cord-022561-rv5j1201	2583	3	is	be	VBZ
cord-022561-rv5j1201	2583	4	an	an	DT
cord-022561-rv5j1201	2583	5	initial	initial	JJ
cord-022561-rv5j1201	2583	6	stage	stage	NN
cord-022561-rv5j1201	2583	7	of	of	IN
cord-022561-rv5j1201	2583	8	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	2583	9	hyperplasia	hyperplasia	NN
cord-022561-rv5j1201	2583	10	in	in	IN
cord-022561-rv5j1201	2583	11	the	the	DT
cord-022561-rv5j1201	2583	12	spleen	spleen	NNS
cord-022561-rv5j1201	2583	13	and	and	CC
cord-022561-rv5j1201	2583	14	lymph	lymph	NN
cord-022561-rv5j1201	2583	15	node	node	NN
cord-022561-rv5j1201	2583	16	,	,	,
cord-022561-rv5j1201	2583	17	subsequent	subsequent	JJ
cord-022561-rv5j1201	2583	18	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	2583	19	atrophy	atrophy	NN
cord-022561-rv5j1201	2583	20	occurs	occur	VBZ
cord-022561-rv5j1201	2583	21	with	with	IN
cord-022561-rv5j1201	2583	22	chronicity	chronicity	NN
cord-022561-rv5j1201	2583	23	.	.	.
cord-022561-rv5j1201	2584	1	The	the	DT
cord-022561-rv5j1201	2584	2	atrophy	atrophy	NN
cord-022561-rv5j1201	2584	3	is	be	VBZ
cord-022561-rv5j1201	2584	4	due	due	JJ
cord-022561-rv5j1201	2584	5	to	to	IN
cord-022561-rv5j1201	2584	6	impairment	impairment	NN
cord-022561-rv5j1201	2584	7	of	of	IN
cord-022561-rv5j1201	2584	8	follicular	follicular	JJ
cord-022561-rv5j1201	2584	9	DCs	dc	NNS
cord-022561-rv5j1201	2584	10	,	,	,
cord-022561-rv5j1201	2584	11	B	b	NN
cord-022561-rv5j1201	2584	12	lymphocyte	lymphocyte	NN
cord-022561-rv5j1201	2584	13	migration	migration	NN
cord-022561-rv5j1201	2584	14	,	,	,
cord-022561-rv5j1201	2584	15	and	and	CC
cord-022561-rv5j1201	2584	16	germinal	germinal	JJ
cord-022561-rv5j1201	2584	17	center	center	NN
cord-022561-rv5j1201	2584	18	formation	formation	NN
cord-022561-rv5j1201	2584	19	.	.	.
cord-022561-rv5j1201	2585	1	There	there	EX
cord-022561-rv5j1201	2585	2	may	may	MD
cord-022561-rv5j1201	2585	3	be	be	VB
cord-022561-rv5j1201	2585	4	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	2585	5	atrophy	atrophy	NN
cord-022561-rv5j1201	2585	6	of	of	IN
cord-022561-rv5j1201	2585	7	the	the	DT
cord-022561-rv5j1201	2585	8	spleen	spleen	NNS
cord-022561-rv5j1201	2585	9	and	and	CC
cord-022561-rv5j1201	2585	10	lymph	lymph	NN
cord-022561-rv5j1201	2585	11	nodes	node	NNS
cord-022561-rv5j1201	2585	12	in	in	IN
cord-022561-rv5j1201	2585	13	severe	severe	JJ
cord-022561-rv5j1201	2585	14	chronic	chronic	JJ
cord-022561-rv5j1201	2585	15	infections	infection	NNS
cord-022561-rv5j1201	2585	16	.	.	.
cord-022561-rv5j1201	2586	1	Canine	canine	JJ
cord-022561-rv5j1201	2586	2	distemper	distemper	NN
cord-022561-rv5j1201	2586	3	virus	virus	NN
cord-022561-rv5j1201	2586	4	preferentially	preferentially	RB
cord-022561-rv5j1201	2586	5	infects	infect	VBZ
cord-022561-rv5j1201	2586	6	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	2586	7	,	,	,
cord-022561-rv5j1201	2586	8	epithelial	epithelial	JJ
cord-022561-rv5j1201	2586	9	,	,	,
cord-022561-rv5j1201	2586	10	and	and	CC
cord-022561-rv5j1201	2586	11	nervous	nervous	JJ
cord-022561-rv5j1201	2586	12	cells	cell	NNS
cord-022561-rv5j1201	2586	13	(	(	-LRB-
cord-022561-rv5j1201	2586	14	see	see	VB
cord-022561-rv5j1201	2586	15	Chapter	chapter	NN
cord-022561-rv5j1201	2586	16	14	14	CD
cord-022561-rv5j1201	2586	17	)	)	-RRB-
cord-022561-rv5j1201	2586	18	.	.	.
cord-022561-rv5j1201	2587	1	Dogs	dog	NNS
cord-022561-rv5j1201	2587	2	are	be	VBP
cord-022561-rv5j1201	2587	3	exposed	expose	VBN
cord-022561-rv5j1201	2587	4	through	through	IN
cord-022561-rv5j1201	2587	5	contact	contact	NN
cord-022561-rv5j1201	2587	6	with	with	IN
cord-022561-rv5j1201	2587	7	oronasal	oronasal	NN
cord-022561-rv5j1201	2587	8	secretions	secretion	NNS
cord-022561-rv5j1201	2587	9	,	,	,
cord-022561-rv5j1201	2587	10	and	and	CC
cord-022561-rv5j1201	2587	11	the	the	DT
cord-022561-rv5j1201	2587	12	virus	virus	NN
cord-022561-rv5j1201	2587	13	infects	infect	VBZ
cord-022561-rv5j1201	2587	14	macrophages	macrophage	NNS
cord-022561-rv5j1201	2587	15	within	within	IN
cord-022561-rv5j1201	2587	16	the	the	DT
cord-022561-rv5j1201	2587	17	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	2587	18	tissue	tissue	NN
cord-022561-rv5j1201	2587	19	of	of	IN
cord-022561-rv5j1201	2587	20	the	the	DT
cord-022561-rv5j1201	2587	21	tonsil	tonsil	JJ
cord-022561-rv5j1201	2587	22	and	and	CC
cord-022561-rv5j1201	2587	23	respiratory	respiratory	JJ
cord-022561-rv5j1201	2587	24	tract	tract	NN
cord-022561-rv5j1201	2587	25	(	(	-LRB-
cord-022561-rv5j1201	2587	26	including	include	VBG
cord-022561-rv5j1201	2587	27	tracheobronchial	tracheobronchial	JJ
cord-022561-rv5j1201	2587	28	lymph	lymph	NN
cord-022561-rv5j1201	2587	29	nodes	node	NNS
cord-022561-rv5j1201	2587	30	)	)	-RRB-
cord-022561-rv5j1201	2587	31	and	and	CC
cord-022561-rv5j1201	2587	32	later	later	RB
cord-022561-rv5j1201	2587	33	disseminates	disseminate	VBZ
cord-022561-rv5j1201	2587	34	to	to	IN
cord-022561-rv5j1201	2587	35	the	the	DT
cord-022561-rv5j1201	2587	36	spleen	spleen	NN
cord-022561-rv5j1201	2587	37	,	,	,
cord-022561-rv5j1201	2587	38	lymph	lymph	NN
cord-022561-rv5j1201	2587	39	nodes	node	NNS
cord-022561-rv5j1201	2587	40	,	,	,
cord-022561-rv5j1201	2587	41	bone	bone	NN
cord-022561-rv5j1201	2587	42	marrow	marrow	NN
cord-022561-rv5j1201	2587	43	,	,	,
cord-022561-rv5j1201	2587	44	MALT	malt	NN
cord-022561-rv5j1201	2587	45	,	,	,
cord-022561-rv5j1201	2587	46	and	and	CC
cord-022561-rv5j1201	2587	47	hepatic	hepatic	JJ
cord-022561-rv5j1201	2587	48	Kupffer	Kupffer	NNP
cord-022561-rv5j1201	2587	49	cells	cell	NNS
cord-022561-rv5j1201	2587	50	.	.	.
cord-022561-rv5j1201	2588	1	The	the	DT
cord-022561-rv5j1201	2588	2	virus	virus	NN
cord-022561-rv5j1201	2588	3	causes	cause	VBZ
cord-022561-rv5j1201	2588	4	necrosis	necrosis	NN
cord-022561-rv5j1201	2588	5	of	of	IN
cord-022561-rv5j1201	2588	6	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	2588	7	(	(	-LRB-
cord-022561-rv5j1201	2588	8	especially	especially	RB
cord-022561-rv5j1201	2588	9	CD4	CD4	NNP
cord-022561-rv5j1201	2588	10	T	T	NNP
cord-022561-rv5j1201	2588	11	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	2588	12	)	)	-RRB-
cord-022561-rv5j1201	2588	13	and	and	CC
cord-022561-rv5j1201	2588	14	depression	depression	NN
cord-022561-rv5j1201	2588	15	of	of	IN
cord-022561-rv5j1201	2588	16	lymphopoiesis	lymphopoiesis	NN
cord-022561-rv5j1201	2588	17	in	in	IN
cord-022561-rv5j1201	2588	18	the	the	DT
cord-022561-rv5j1201	2588	19	bone	bone	NN
cord-022561-rv5j1201	2588	20	marrow	marrow	NN
cord-022561-rv5j1201	2588	21	,	,	,
cord-022561-rv5j1201	2588	22	leading	lead	VBG
cord-022561-rv5j1201	2588	23	to	to	IN
cord-022561-rv5j1201	2588	24	severe	severe	JJ
cord-022561-rv5j1201	2588	25	immunosuppression	immunosuppression	NN
cord-022561-rv5j1201	2588	26	.	.	.
cord-022561-rv5j1201	2589	1	Dogs	dog	NNS
cord-022561-rv5j1201	2589	2	are	be	VBP
cord-022561-rv5j1201	2589	3	therefore	therefore	RB
cord-022561-rv5j1201	2589	4	susceptible	susceptible	JJ
cord-022561-rv5j1201	2589	5	to	to	IN
cord-022561-rv5j1201	2589	6	secondary	secondary	JJ
cord-022561-rv5j1201	2589	7	infections	infection	NNS
cord-022561-rv5j1201	2589	8	,	,	,
cord-022561-rv5j1201	2589	9	including	include	VBG
cord-022561-rv5j1201	2589	10	Bordetella	Bordetella	NNP
cord-022561-rv5j1201	2589	11	bronchiseptica	bronchiseptica	NNP
cord-022561-rv5j1201	2589	12	,	,	,
cord-022561-rv5j1201	2589	13	Toxoplasma	toxoplasma	NN
cord-022561-rv5j1201	2589	14	gondii	gondii	NN
cord-022561-rv5j1201	2589	15	,	,	,
cord-022561-rv5j1201	2589	16	Nocardia	Nocardia	NNP
cord-022561-rv5j1201	2589	17	,	,	,
cord-022561-rv5j1201	2589	18	Salmonella	Salmonella	NNP
cord-022561-rv5j1201	2589	19	spp	spp	NNS
cord-022561-rv5j1201	2589	20	.	.	.
cord-022561-rv5j1201	2590	1	,	,	,
cord-022561-rv5j1201	2590	2	and	and	CC
cord-022561-rv5j1201	2590	3	generalized	generalize	VBD
cord-022561-rv5j1201	2590	4	demodicosis	demodicosis	NN
cord-022561-rv5j1201	2590	5	.	.	.
cord-022561-rv5j1201	2591	1	Canine	canine	JJ
cord-022561-rv5j1201	2591	2	parvovirus	parvovirus	NN
cord-022561-rv5j1201	2591	3	type	type	NN
cord-022561-rv5j1201	2591	4	2	2	CD
cord-022561-rv5j1201	2592	1	(	(	-LRB-
cord-022561-rv5j1201	2592	2	CPV-2	CPV-2	NNP
cord-022561-rv5j1201	2592	3	)	)	-RRB-
cord-022561-rv5j1201	2592	4	is	be	VBZ
cord-022561-rv5j1201	2592	5	a	a	DT
cord-022561-rv5j1201	2592	6	highly	highly	RB
cord-022561-rv5j1201	2592	7	contagious	contagious	JJ
cord-022561-rv5j1201	2592	8	disease	disease	NN
cord-022561-rv5j1201	2592	9	of	of	IN
cord-022561-rv5j1201	2592	10	dogs	dog	NNS
cord-022561-rv5j1201	2592	11	spread	spread	VBD
cord-022561-rv5j1201	2592	12	through	through	IN
cord-022561-rv5j1201	2592	13	the	the	DT
cord-022561-rv5j1201	2592	14	fecal	fecal	JJ
cord-022561-rv5j1201	2592	15	-	-	HYPH
cord-022561-rv5j1201	2592	16	oral	oral	JJ
cord-022561-rv5j1201	2592	17	route	route	NN
cord-022561-rv5j1201	2592	18	or	or	CC
cord-022561-rv5j1201	2592	19	oronasal	oronasal	NN
cord-022561-rv5j1201	2592	20	exposure	exposure	NN
cord-022561-rv5j1201	2592	21	to	to	IN
cord-022561-rv5j1201	2592	22	contaminated	contaminate	VBN
cord-022561-rv5j1201	2592	23	fomites	fomite	NNS
cord-022561-rv5j1201	2592	24	.	.	.
cord-022561-rv5j1201	2593	1	The	the	DT
cord-022561-rv5j1201	2593	2	virus	virus	NN
cord-022561-rv5j1201	2593	3	has	have	VBZ
cord-022561-rv5j1201	2593	4	tropism	tropism	NN
cord-022561-rv5j1201	2593	5	for	for	IN
cord-022561-rv5j1201	2593	6	rapidly	rapidly	RB
cord-022561-rv5j1201	2593	7	dividing	divide	VBG
cord-022561-rv5j1201	2593	8	cells	cell	NNS
cord-022561-rv5j1201	2593	9	,	,	,
cord-022561-rv5j1201	2593	10	and	and	CC
cord-022561-rv5j1201	2593	11	replication	replication	NN
cord-022561-rv5j1201	2593	12	begins	begin	VBZ
cord-022561-rv5j1201	2593	13	in	in	IN
cord-022561-rv5j1201	2593	14	the	the	DT
cord-022561-rv5j1201	2593	15	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	2593	16	tissues	tissue	NNS
cord-022561-rv5j1201	2593	17	of	of	IN
cord-022561-rv5j1201	2593	18	the	the	DT
cord-022561-rv5j1201	2593	19	oropharynx	oropharynx	NN
cord-022561-rv5j1201	2593	20	,	,	,
cord-022561-rv5j1201	2593	21	thymus	thymus	NN
cord-022561-rv5j1201	2593	22	,	,	,
cord-022561-rv5j1201	2593	23	and	and	CC
cord-022561-rv5j1201	2593	24	mesenteric	mesenteric	JJ
cord-022561-rv5j1201	2593	25	lymph	lymph	NN
cord-022561-rv5j1201	2593	26	nodes	node	NNS
cord-022561-rv5j1201	2593	27	and	and	CC
cord-022561-rv5j1201	2593	28	then	then	RB
cord-022561-rv5j1201	2593	29	is	be	VBZ
cord-022561-rv5j1201	2593	30	disseminated	disseminate	VBN
cord-022561-rv5j1201	2593	31	to	to	IN
cord-022561-rv5j1201	2593	32	the	the	DT
cord-022561-rv5j1201	2593	33	small	small	JJ
cord-022561-rv5j1201	2593	34	intestinal	intestinal	JJ
cord-022561-rv5j1201	2593	35	crypt	crypt	NN
cord-022561-rv5j1201	2593	36	epithelium	epithelium	NN
cord-022561-rv5j1201	2593	37	.	.	.
cord-022561-rv5j1201	2594	1	By	by	IN
cord-022561-rv5j1201	2594	2	infecting	infect	VBG
cord-022561-rv5j1201	2594	3	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	2594	4	tissues	tissue	NNS
cord-022561-rv5j1201	2594	5	,	,	,
cord-022561-rv5j1201	2594	6	canine	canine	JJ
cord-022561-rv5j1201	2594	7	parvovirus	parvovirus	NN
cord-022561-rv5j1201	2594	8	type	type	NN
cord-022561-rv5j1201	2594	9	2	2	CD
cord-022561-rv5j1201	2594	10	causes	cause	VBZ
cord-022561-rv5j1201	2594	11	immunosuppression	immunosuppression	NN
cord-022561-rv5j1201	2594	12	directly	directly	RB
cord-022561-rv5j1201	2594	13	through	through	IN
cord-022561-rv5j1201	2594	14	lymphocytolysis	lymphocytolysis	NNP
cord-022561-rv5j1201	2594	15	and	and	CC
cord-022561-rv5j1201	2594	16	indirectly	indirectly	RB
cord-022561-rv5j1201	2594	17	though	though	IN
cord-022561-rv5j1201	2594	18	bone	bone	NN
cord-022561-rv5j1201	2594	19	marrow	marrow	NN
cord-022561-rv5j1201	2594	20	depletion	depletion	NN
cord-022561-rv5j1201	2594	21	of	of	IN
cord-022561-rv5j1201	2594	22	lymphocyte	lymphocyte	NN
cord-022561-rv5j1201	2594	23	precursors	precursor	NNS
cord-022561-rv5j1201	2594	24	.	.	.
cord-022561-rv5j1201	2595	1	There	there	EX
cord-022561-rv5j1201	2595	2	is	be	VBZ
cord-022561-rv5j1201	2595	3	marked	mark	VBN
cord-022561-rv5j1201	2595	4	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	2595	5	atrophy	atrophy	NN
cord-022561-rv5j1201	2595	6	of	of	IN
cord-022561-rv5j1201	2595	7	thymus	thymus	NN
cord-022561-rv5j1201	2595	8	and	and	CC
cord-022561-rv5j1201	2595	9	follicles	follicle	NNS
cord-022561-rv5j1201	2595	10	of	of	IN
cord-022561-rv5j1201	2595	11	the	the	DT
cord-022561-rv5j1201	2595	12	spleen	spleen	NN
cord-022561-rv5j1201	2595	13	,	,	,
cord-022561-rv5j1201	2595	14	lymph	lymph	NN
cord-022561-rv5j1201	2595	15	nodes	node	NNS
cord-022561-rv5j1201	2595	16	,	,	,
cord-022561-rv5j1201	2595	17	and	and	CC
cord-022561-rv5j1201	2595	18	MALTparticularly	maltparticularly	RB
cord-022561-rv5j1201	2595	19	of	of	IN
cord-022561-rv5j1201	2595	20	Peyer	Peyer	NNP
cord-022561-rv5j1201	2595	21	's	's	POS
cord-022561-rv5j1201	2595	22	patches	patch	NNS
cord-022561-rv5j1201	2595	23	to	to	TO
cord-022561-rv5j1201	2595	24	produce	produce	VB
cord-022561-rv5j1201	2595	25	the	the	DT
cord-022561-rv5j1201	2595	26	classic	classic	JJ
cord-022561-rv5j1201	2595	27	gross	gross	JJ
cord-022561-rv5j1201	2595	28	lesion	lesion	NN
cord-022561-rv5j1201	2595	29	of	of	IN
cord-022561-rv5j1201	2595	30	depressed	depressed	JJ
cord-022561-rv5j1201	2595	31	oval	oval	JJ
cord-022561-rv5j1201	2595	32	regions	region	NNS
cord-022561-rv5j1201	2595	33	of	of	IN
cord-022561-rv5j1201	2595	34	the	the	DT
cord-022561-rv5j1201	2595	35	mucosa	mucosa	NN
cord-022561-rv5j1201	2595	36	(	(	-LRB-
cord-022561-rv5j1201	2595	37	so	so	RB
cord-022561-rv5j1201	2595	38	-	-	HYPH
cord-022561-rv5j1201	2595	39	called	call	VBN
cord-022561-rv5j1201	2595	40	punched	punch	VBN
cord-022561-rv5j1201	2595	41	-	-	HYPH
cord-022561-rv5j1201	2595	42	out	out	RP
cord-022561-rv5j1201	2595	43	Peyer	Peyer	NNP
cord-022561-rv5j1201	2595	44	's	's	POS
cord-022561-rv5j1201	2595	45	patches	patch	NNS
cord-022561-rv5j1201	2595	46	)	)	-RRB-
cord-022561-rv5j1201	2595	47	.	.	.
cord-022561-rv5j1201	2596	1	Thymomas	Thymomas	NNP
cord-022561-rv5j1201	2596	2	.	.	.
cord-022561-rv5j1201	2597	1	See	see	VB
cord-022561-rv5j1201	2598	1	Lymphoid	lymphoid	JJ
cord-022561-rv5j1201	2598	2	/	/	SYM
cord-022561-rv5j1201	2598	3	Lymphatic	Lymphatic	NNP
cord-022561-rv5j1201	2598	4	System	System	NNP
cord-022561-rv5j1201	2598	5	,	,	,
cord-022561-rv5j1201	2598	6	Disorders	disorder	NNS
cord-022561-rv5j1201	2598	7	of	of	IN
cord-022561-rv5j1201	2598	8	Domestic	domestic	JJ
cord-022561-rv5j1201	2598	9	Animals	animal	NNS
cord-022561-rv5j1201	2598	10	:	:	:
cord-022561-rv5j1201	2598	11	Thymus	thymus	NN
cord-022561-rv5j1201	2598	12	,	,	,
cord-022561-rv5j1201	2598	13	Neoplasia	Neoplasia	NNP
cord-022561-rv5j1201	2598	14	.	.	.
cord-022561-rv5j1201	2599	1	Lymphomas	lymphoma	NNS
cord-022561-rv5j1201	2599	2	.	.	.
cord-022561-rv5j1201	2600	1	Lymphoma	Lymphoma	NNP
cord-022561-rv5j1201	2600	2	is	be	VBZ
cord-022561-rv5j1201	2600	3	the	the	DT
cord-022561-rv5j1201	2600	4	most	most	RBS
cord-022561-rv5j1201	2600	5	common	common	JJ
cord-022561-rv5j1201	2600	6	hematologic	hematologic	JJ
cord-022561-rv5j1201	2600	7	malignancy	malignancy	NN
cord-022561-rv5j1201	2600	8	in	in	IN
cord-022561-rv5j1201	2600	9	the	the	DT
cord-022561-rv5j1201	2600	10	dog	dog	NN
cord-022561-rv5j1201	2600	11	.	.	.
cord-022561-rv5j1201	2601	1	Using	use	VBG
cord-022561-rv5j1201	2601	2	the	the	DT
cord-022561-rv5j1201	2601	3	WHO	who	WP
cord-022561-rv5j1201	2601	4	classification	classification	NN
cord-022561-rv5j1201	2601	5	scheme	scheme	NN
cord-022561-rv5j1201	2601	6	,	,	,
cord-022561-rv5j1201	2601	7	several	several	JJ
cord-022561-rv5j1201	2601	8	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2601	9	subtypes	subtype	NNS
cord-022561-rv5j1201	2601	10	are	be	VBP
cord-022561-rv5j1201	2601	11	identified	identify	VBN
cord-022561-rv5j1201	2601	12	in	in	IN
cord-022561-rv5j1201	2601	13	dogs	dog	NNS
cord-022561-rv5j1201	2601	14	and	and	CC
cord-022561-rv5j1201	2601	15	clinically	clinically	RB
cord-022561-rv5j1201	2601	16	range	range	VBP
cord-022561-rv5j1201	2601	17	from	from	IN
cord-022561-rv5j1201	2601	18	slow	slow	RB
cord-022561-rv5j1201	2601	19	-	-	HYPH
cord-022561-rv5j1201	2601	20	growing	grow	VBG
cord-022561-rv5j1201	2601	21	indolent	indolent	JJ
cord-022561-rv5j1201	2601	22	tumors	tumor	NNS
cord-022561-rv5j1201	2601	23	to	to	IN
cord-022561-rv5j1201	2601	24	highly	highly	RB
cord-022561-rv5j1201	2601	25	aggressive	aggressive	JJ
cord-022561-rv5j1201	2601	26	tumors	tumor	NNS
cord-022561-rv5j1201	2601	27	.	.	.
cord-022561-rv5j1201	2602	1	Of	of	IN
cord-022561-rv5j1201	2602	2	all	all	DT
cord-022561-rv5j1201	2602	3	domestic	domestic	JJ
cord-022561-rv5j1201	2602	4	animal	animal	NN
cord-022561-rv5j1201	2602	5	species	specie	NNS
cord-022561-rv5j1201	2602	6	,	,	,
cord-022561-rv5j1201	2602	7	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2602	8	is	be	VBZ
cord-022561-rv5j1201	2602	9	the	the	DT
cord-022561-rv5j1201	2602	10	most	most	RBS
cord-022561-rv5j1201	2602	11	extensively	extensively	RB
cord-022561-rv5j1201	2602	12	studied	study	VBN
cord-022561-rv5j1201	2602	13	in	in	IN
cord-022561-rv5j1201	2602	14	dogs	dog	NNS
cord-022561-rv5j1201	2602	15	.	.	.
cord-022561-rv5j1201	2603	1	The	the	DT
cord-022561-rv5j1201	2603	2	most	most	RBS
cord-022561-rv5j1201	2603	3	common	common	JJ
cord-022561-rv5j1201	2603	4	clinical	clinical	JJ
cord-022561-rv5j1201	2603	5	presentation	presentation	NN
cord-022561-rv5j1201	2603	6	in	in	IN
cord-022561-rv5j1201	2603	7	dogs	dog	NNS
cord-022561-rv5j1201	2603	8	is	be	VBZ
cord-022561-rv5j1201	2603	9	generalized	generalize	VBN
cord-022561-rv5j1201	2603	10	lymphadenopathy	lymphadenopathy	JJ
cord-022561-rv5j1201	2603	11	,	,	,
cord-022561-rv5j1201	2603	12	with	with	IN
cord-022561-rv5j1201	2603	13	or	or	CC
cord-022561-rv5j1201	2603	14	without	without	IN
cord-022561-rv5j1201	2603	15	clinical	clinical	JJ
cord-022561-rv5j1201	2603	16	signs	sign	NNS
cord-022561-rv5j1201	2603	17	such	such	JJ
cord-022561-rv5j1201	2603	18	as	as	IN
cord-022561-rv5j1201	2603	19	lethargy	lethargy	NN
cord-022561-rv5j1201	2603	20	and	and	CC
cord-022561-rv5j1201	2603	21	inappetence	inappetence	NN
cord-022561-rv5j1201	2603	22	.	.	.
cord-022561-rv5j1201	2604	1	The	the	DT
cord-022561-rv5j1201	2604	2	majority	majority	NN
cord-022561-rv5j1201	2604	3	of	of	IN
cord-022561-rv5j1201	2604	4	lymphomas	lymphoma	NNS
cord-022561-rv5j1201	2604	5	in	in	IN
cord-022561-rv5j1201	2604	6	dogs	dog	NNS
cord-022561-rv5j1201	2604	7	are	be	VBP
cord-022561-rv5j1201	2604	8	large	large	JJ
cord-022561-rv5j1201	2604	9	cell	cell	NN
cord-022561-rv5j1201	2604	10	mid	mid	NN
cord-022561-rv5j1201	2604	11	-	-	JJ
cord-022561-rv5j1201	2604	12	to	to	IN
cord-022561-rv5j1201	2604	13	highgrade	highgrade	JJ
cord-022561-rv5j1201	2604	14	lymphomas	lymphoma	NNS
cord-022561-rv5j1201	2604	15	,	,	,
cord-022561-rv5j1201	2604	16	and	and	CC
cord-022561-rv5j1201	2604	17	up	up	IN
cord-022561-rv5j1201	2604	18	to	to	TO
cord-022561-rv5j1201	2604	19	half	half	NN
cord-022561-rv5j1201	2604	20	of	of	IN
cord-022561-rv5j1201	2604	21	all	all	DT
cord-022561-rv5j1201	2604	22	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2604	23	cases	case	NNS
cord-022561-rv5j1201	2604	24	are	be	VBP
cord-022561-rv5j1201	2604	25	subtyped	subtyped	JJ
cord-022561-rv5j1201	2604	26	as	as	IN
cord-022561-rv5j1201	2604	27	diffuse	diffuse	JJ
cord-022561-rv5j1201	2604	28	large	large	JJ
cord-022561-rv5j1201	2604	29	B	b	NN
cord-022561-rv5j1201	2604	30	cell	cell	NN
cord-022561-rv5j1201	2604	31	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2604	32	.	.	.
cord-022561-rv5j1201	2605	1	Diffuse	diffuse	VB
cord-022561-rv5j1201	2605	2	large	large	JJ
cord-022561-rv5j1201	2605	3	B	b	NN
cord-022561-rv5j1201	2605	4	cell	cell	NN
cord-022561-rv5j1201	2605	5	lymphomas	lymphoma	NNS
cord-022561-rv5j1201	2605	6	are	be	VBP
cord-022561-rv5j1201	2605	7	further	further	RB
cord-022561-rv5j1201	2605	8	subdivided	subdivide	VBN
cord-022561-rv5j1201	2605	9	into	into	IN
cord-022561-rv5j1201	2605	10	centroblastic	centroblastic	NNP
cord-022561-rv5j1201	2605	11	or	or	CC
cord-022561-rv5j1201	2605	12	immunoblastic	immunoblastic	NNP
cord-022561-rv5j1201	2605	13	based	base	VBN
cord-022561-rv5j1201	2605	14	on	on	IN
cord-022561-rv5j1201	2605	15	nucleolar	nucleolar	JJ
cord-022561-rv5j1201	2605	16	morphologic	morphologic	JJ
cord-022561-rv5j1201	2605	17	features	feature	NNS
cord-022561-rv5j1201	2605	18	(	(	-LRB-
cord-022561-rv5j1201	2605	19	see	see	VB
cord-022561-rv5j1201	2605	20	Table	Table	NNP
cord-022561-rv5j1201	2605	21	13	13	CD
cord-022561-rv5j1201	2605	22	-7	-7	CD
cord-022561-rv5j1201	2605	23	and	and	CC
cord-022561-rv5j1201	2605	24	Box	Box	NNP
cord-022561-rv5j1201	2605	25	13	13	CD
cord-022561-rv5j1201	2605	26	-	-	SYM
cord-022561-rv5j1201	2605	27	11	11	CD
cord-022561-rv5j1201	2605	28	)	)	-RRB-
cord-022561-rv5j1201	2605	29	,	,	,
cord-022561-rv5j1201	2605	30	although	although	IN
cord-022561-rv5j1201	2605	31	it	-PRON-	PRP
cord-022561-rv5j1201	2605	32	is	be	VBZ
cord-022561-rv5j1201	2605	33	unclear	unclear	JJ
cord-022561-rv5j1201	2605	34	if	if	IN
cord-022561-rv5j1201	2605	35	this	this	DT
cord-022561-rv5j1201	2605	36	difference	difference	NN
cord-022561-rv5j1201	2605	37	has	have	VBZ
cord-022561-rv5j1201	2605	38	any	any	DT
cord-022561-rv5j1201	2605	39	prognostic	prognostic	JJ
cord-022561-rv5j1201	2605	40	significance	significance	NN
cord-022561-rv5j1201	2605	41	.	.	.
cord-022561-rv5j1201	2606	1	Histologically	histologically	RB
cord-022561-rv5j1201	2606	2	,	,	,
cord-022561-rv5j1201	2606	3	lymph	lymph	NN
cord-022561-rv5j1201	2606	4	node	node	NN
cord-022561-rv5j1201	2606	5	architecture	architecture	NN
cord-022561-rv5j1201	2606	6	is	be	VBZ
cord-022561-rv5j1201	2606	7	most	most	RBS
cord-022561-rv5j1201	2606	8	often	often	RB
cord-022561-rv5j1201	2606	9	completely	completely	RB
cord-022561-rv5j1201	2606	10	effaced	efface	VBN
cord-022561-rv5j1201	2606	11	by	by	IN
cord-022561-rv5j1201	2606	12	sheets	sheet	NNS
cord-022561-rv5j1201	2606	13	of	of	IN
cord-022561-rv5j1201	2606	14	large	large	JJ
cord-022561-rv5j1201	2606	15	neoplastic	neoplastic	JJ
cord-022561-rv5j1201	2606	16	cells	cell	NNS
cord-022561-rv5j1201	2606	17	,	,	,
cord-022561-rv5j1201	2606	18	which	which	WDT
cord-022561-rv5j1201	2606	19	may	may	MD
cord-022561-rv5j1201	2606	20	invade	invade	VB
cord-022561-rv5j1201	2606	21	through	through	IN
cord-022561-rv5j1201	2606	22	the	the	DT
cord-022561-rv5j1201	2606	23	capsule	capsule	NN
cord-022561-rv5j1201	2606	24	and	and	CC
cord-022561-rv5j1201	2606	25	colonize	colonize	VB
cord-022561-rv5j1201	2606	26	the	the	DT
cord-022561-rv5j1201	2606	27	perinodal	perinodal	JJ
cord-022561-rv5j1201	2606	28	tissue	tissue	NN
cord-022561-rv5j1201	2606	29	.	.	.
cord-022561-rv5j1201	2607	1	These	these	DT
cord-022561-rv5j1201	2607	2	dogs	dog	NNS
cord-022561-rv5j1201	2607	3	are	be	VBP
cord-022561-rv5j1201	2607	4	often	often	RB
cord-022561-rv5j1201	2607	5	treated	treat	VBN
cord-022561-rv5j1201	2607	6	with	with	IN
cord-022561-rv5j1201	2607	7	chemotherapy	chemotherapy	NN
cord-022561-rv5j1201	2607	8	and	and	CC
cord-022561-rv5j1201	2607	9	achieve	achieve	VB
cord-022561-rv5j1201	2607	10	remission	remission	NN
cord-022561-rv5j1201	2607	11	.	.	.
cord-022561-rv5j1201	2608	1	The	the	DT
cord-022561-rv5j1201	2608	2	overall	overall	JJ
cord-022561-rv5j1201	2608	3	median	median	JJ
cord-022561-rv5j1201	2608	4	survival	survival	NN
cord-022561-rv5j1201	2608	5	time	time	NN
cord-022561-rv5j1201	2608	6	for	for	IN
cord-022561-rv5j1201	2608	7	dogs	dog	NNS
cord-022561-rv5j1201	2608	8	with	with	IN
cord-022561-rv5j1201	2608	9	diffuse	diffuse	JJ
cord-022561-rv5j1201	2608	10	large	large	JJ
cord-022561-rv5j1201	2608	11	B	b	NN
cord-022561-rv5j1201	2608	12	lymphocyte	lymphocyte	NN
cord-022561-rv5j1201	2608	13	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2608	14	is	be	VBZ
cord-022561-rv5j1201	2608	15	approximately	approximately	RB
cord-022561-rv5j1201	2608	16	7	7	CD
cord-022561-rv5j1201	2608	17	months	month	NNS
cord-022561-rv5j1201	2608	18	,	,	,
cord-022561-rv5j1201	2608	19	although	although	IN
cord-022561-rv5j1201	2608	20	this	this	DT
cord-022561-rv5j1201	2608	21	number	number	NN
cord-022561-rv5j1201	2608	22	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2608	23	,	,	,
cord-022561-rv5j1201	2608	24	though	though	IN
cord-022561-rv5j1201	2608	25	the	the	DT
cord-022561-rv5j1201	2608	26	nodes	node	NNS
cord-022561-rv5j1201	2608	27	tend	tend	VBP
cord-022561-rv5j1201	2608	28	to	to	TO
cord-022561-rv5j1201	2608	29	be	be	VB
cord-022561-rv5j1201	2608	30	more	more	RBR
cord-022561-rv5j1201	2608	31	firm	firm	JJ
cord-022561-rv5j1201	2608	32	in	in	IN
cord-022561-rv5j1201	2608	33	histoplasmosis	histoplasmosis	NN
cord-022561-rv5j1201	2608	34	)	)	-RRB-
cord-022561-rv5j1201	2608	35	.	.	.
cord-022561-rv5j1201	2609	1	Histologically	histologically	RB
cord-022561-rv5j1201	2609	2	within	within	IN
cord-022561-rv5j1201	2609	3	the	the	DT
cord-022561-rv5j1201	2609	4	node	node	NN
cord-022561-rv5j1201	2609	5	,	,	,
cord-022561-rv5j1201	2609	6	there	there	EX
cord-022561-rv5j1201	2609	7	is	be	VBZ
cord-022561-rv5j1201	2609	8	a	a	DT
cord-022561-rv5j1201	2609	9	multifocal	multifocal	JJ
cord-022561-rv5j1201	2609	10	to	to	IN
cord-022561-rv5j1201	2609	11	coalescing	coalesce	VBG
cord-022561-rv5j1201	2609	12	infiltrate	infiltrate	NN
cord-022561-rv5j1201	2609	13	of	of	IN
cord-022561-rv5j1201	2609	14	epithelioid	epithelioid	JJ
cord-022561-rv5j1201	2609	15	macrophages	macrophage	NNS
cord-022561-rv5j1201	2609	16	with	with	IN
cord-022561-rv5j1201	2609	17	intracytoplasmic	intracytoplasmic	JJ
cord-022561-rv5j1201	2609	18	,	,	,
cord-022561-rv5j1201	2609	19	small	small	JJ
cord-022561-rv5j1201	2609	20	(	(	-LRB-
cord-022561-rv5j1201	2609	21	2	2	CD
cord-022561-rv5j1201	2609	22	to	to	TO
cord-022561-rv5j1201	2609	23	4	4	CD
cord-022561-rv5j1201	2609	24	µm	µm	NN
cord-022561-rv5j1201	2609	25	in	in	IN
cord-022561-rv5j1201	2609	26	diameter	diameter	NN
cord-022561-rv5j1201	2609	27	)	)	-RRB-
cord-022561-rv5j1201	2610	1	yeast	yeast	NN
cord-022561-rv5j1201	2610	2	organisms	organism	NNS
cord-022561-rv5j1201	2610	3	with	with	IN
cord-022561-rv5j1201	2610	4	spherical	spherical	JJ
cord-022561-rv5j1201	2610	5	basophilic	basophilic	JJ
cord-022561-rv5j1201	2610	6	central	central	JJ
cord-022561-rv5j1201	2610	7	bodies	body	NNS
cord-022561-rv5j1201	2610	8	surrounded	surround	VBN
cord-022561-rv5j1201	2610	9	by	by	IN
cord-022561-rv5j1201	2610	10	a	a	DT
cord-022561-rv5j1201	2610	11	clear	clear	JJ
cord-022561-rv5j1201	2610	12	halo	halo	NN
cord-022561-rv5j1201	2610	13	(	(	-LRB-
cord-022561-rv5j1201	2610	14	Fig	Fig	NNP
cord-022561-rv5j1201	2610	15	.	.	.
cord-022561-rv5j1201	2610	16	13	13	CD
cord-022561-rv5j1201	2610	17	-	-	SYM
cord-022561-rv5j1201	2610	18	92	92	CD
cord-022561-rv5j1201	2610	19	)	)	-RRB-
cord-022561-rv5j1201	2610	20	.	.	.
cord-022561-rv5j1201	2611	1	Leishmaniasis	leishmaniasis	NN
cord-022561-rv5j1201	2611	2	is	be	VBZ
cord-022561-rv5j1201	2611	3	a	a	DT
cord-022561-rv5j1201	2611	4	disease	disease	NN
cord-022561-rv5j1201	2611	5	of	of	IN
cord-022561-rv5j1201	2611	6	the	the	DT
cord-022561-rv5j1201	2611	7	monocyte	monocyte	JJ
cord-022561-rv5j1201	2611	8	-	-	HYPH
cord-022561-rv5j1201	2611	9	macrophage	macrophage	NN
cord-022561-rv5j1201	2611	10	system	system	NN
cord-022561-rv5j1201	2611	11	caused	cause	VBN
cord-022561-rv5j1201	2611	12	by	by	IN
cord-022561-rv5j1201	2611	13	protozoa	protozoan	NNS
cord-022561-rv5j1201	2611	14	of	of	IN
cord-022561-rv5j1201	2611	15	the	the	DT
cord-022561-rv5j1201	2611	16	genus	genus	NN
cord-022561-rv5j1201	2611	17	Leishmania	Leishmania	NNP
cord-022561-rv5j1201	2611	18	.	.	.
cord-022561-rv5j1201	2612	1	It	-PRON-	PRP
cord-022561-rv5j1201	2612	2	occurs	occur	VBZ
cord-022561-rv5j1201	2612	3	in	in	IN
cord-022561-rv5j1201	2612	4	dogs	dog	NNS
cord-022561-rv5j1201	2612	5	and	and	CC
cord-022561-rv5j1201	2612	6	other	other	JJ
cord-022561-rv5j1201	2612	7	animals	animal	NNS
cord-022561-rv5j1201	2612	8	and	and	CC
cord-022561-rv5j1201	2612	9	is	be	VBZ
cord-022561-rv5j1201	2612	10	endemic	endemic	JJ
cord-022561-rv5j1201	2612	11	in	in	IN
cord-022561-rv5j1201	2612	12	parts	part	NNS
cord-022561-rv5j1201	2612	13	of	of	IN
cord-022561-rv5j1201	2612	14	the	the	DT
cord-022561-rv5j1201	2612	15	United	United	NNP
cord-022561-rv5j1201	2612	16	States	States	NNP
cord-022561-rv5j1201	2612	17	,	,	,
cord-022561-rv5j1201	2612	18	Europe	Europe	NNP
cord-022561-rv5j1201	2612	19	,	,	,
cord-022561-rv5j1201	2612	20	Mediterranean	Mediterranean	NNP
cord-022561-rv5j1201	2612	21	,	,	,
cord-022561-rv5j1201	2612	22	Middle	Middle	NNP
cord-022561-rv5j1201	2612	23	East	East	NNP
cord-022561-rv5j1201	2612	24	,	,	,
cord-022561-rv5j1201	2612	25	Africa	Africa	NNP
cord-022561-rv5j1201	2612	26	,	,	,
cord-022561-rv5j1201	2612	27	and	and	CC
cord-022561-rv5j1201	2612	28	Central	Central	NNP
cord-022561-rv5j1201	2612	29	and	and	CC
cord-022561-rv5j1201	2612	30	South	South	NNP
cord-022561-rv5j1201	2612	31	America	America	NNP
cord-022561-rv5j1201	2612	32	.	.	.
cord-022561-rv5j1201	2613	1	The	the	DT
cord-022561-rv5j1201	2613	2	protozoa	protozoan	NNS
cord-022561-rv5j1201	2613	3	proliferate	proliferate	VBP
cord-022561-rv5j1201	2613	4	by	by	IN
cord-022561-rv5j1201	2613	5	binary	binary	JJ
cord-022561-rv5j1201	2613	6	fission	fission	NN
cord-022561-rv5j1201	2613	7	in	in	IN
cord-022561-rv5j1201	2613	8	the	the	DT
cord-022561-rv5j1201	2613	9	gut	gut	NN
cord-022561-rv5j1201	2613	10	of	of	IN
cord-022561-rv5j1201	2613	11	the	the	DT
cord-022561-rv5j1201	2613	12	sand	sand	NN
cord-022561-rv5j1201	2613	13	fly	fly	VB
cord-022561-rv5j1201	2613	14	and	and	CC
cord-022561-rv5j1201	2613	15	become	become	VB
cord-022561-rv5j1201	2613	16	flagellated	flagellated	JJ
cord-022561-rv5j1201	2613	17	organisms	organism	NNS
cord-022561-rv5j1201	2613	18	,	,	,
cord-022561-rv5j1201	2613	19	which	which	WDT
cord-022561-rv5j1201	2613	20	are	be	VBP
cord-022561-rv5j1201	2613	21	introduced	introduce	VBN
cord-022561-rv5j1201	2613	22	into	into	IN
cord-022561-rv5j1201	2613	23	mammals	mammal	NNS
cord-022561-rv5j1201	2613	24	by	by	IN
cord-022561-rv5j1201	2613	25	insect	insect	NN
cord-022561-rv5j1201	2613	26	bites	bite	NNS
cord-022561-rv5j1201	2613	27	,	,	,
cord-022561-rv5j1201	2613	28	where	where	WRB
cord-022561-rv5j1201	2613	29	they	-PRON-	PRP
cord-022561-rv5j1201	2613	30	are	be	VBP
cord-022561-rv5j1201	2613	31	phagocytized	phagocytize	VBN
cord-022561-rv5j1201	2613	32	by	by	IN
cord-022561-rv5j1201	2613	33	macrophages	macrophage	NNS
cord-022561-rv5j1201	2613	34	and	and	CC
cord-022561-rv5j1201	2613	35	assume	assume	VB
cord-022561-rv5j1201	2613	36	a	a	DT
cord-022561-rv5j1201	2613	37	nonflagellated	nonflagellated	JJ
cord-022561-rv5j1201	2613	38	form	form	NN
cord-022561-rv5j1201	2613	39	.	.	.
cord-022561-rv5j1201	2614	1	Cutaneous	cutaneous	JJ
cord-022561-rv5j1201	2614	2	and/or	and/or	CC
cord-022561-rv5j1201	2614	3	visceral	visceral	JJ
cord-022561-rv5j1201	2614	4	forms	form	NNS
cord-022561-rv5j1201	2614	5	of	of	IN
cord-022561-rv5j1201	2614	6	the	the	DT
cord-022561-rv5j1201	2614	7	disease	disease	NN
cord-022561-rv5j1201	2614	8	are	be	VBP
cord-022561-rv5j1201	2614	9	observed	observe	VBN
cord-022561-rv5j1201	2614	10	.	.	.
cord-022561-rv5j1201	2615	1	In	in	IN
cord-022561-rv5j1201	2615	2	the	the	DT
cord-022561-rv5j1201	2615	3	visceral	visceral	JJ
cord-022561-rv5j1201	2615	4	form	form	NN
cord-022561-rv5j1201	2615	5	,	,	,
cord-022561-rv5j1201	2615	6	dogs	dog	NNS
cord-022561-rv5j1201	2615	7	are	be	VBP
cord-022561-rv5j1201	2615	8	emaciated	emaciated	JJ
cord-022561-rv5j1201	2615	9	and	and	CC
cord-022561-rv5j1201	2615	10	have	have	VBP
cord-022561-rv5j1201	2615	11	general	general	JJ
cord-022561-rv5j1201	2615	12	enlargement	enlargement	NN
cord-022561-rv5j1201	2615	13	of	of	IN
cord-022561-rv5j1201	2615	14	abdominal	abdominal	JJ
cord-022561-rv5j1201	2615	15	lymph	lymph	NN
cord-022561-rv5j1201	2615	16	nodes	node	NNS
cord-022561-rv5j1201	2616	1	Numerous	numerous	JJ
cord-022561-rv5j1201	2616	2	other	other	JJ
cord-022561-rv5j1201	2616	3	subtypes	subtype	NNS
cord-022561-rv5j1201	2616	4	of	of	IN
cord-022561-rv5j1201	2616	5	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2616	6	have	have	VBP
cord-022561-rv5j1201	2616	7	been	be	VBN
cord-022561-rv5j1201	2616	8	reported	report	VBN
cord-022561-rv5j1201	2616	9	in	in	IN
cord-022561-rv5j1201	2616	10	dogs	dog	NNS
cord-022561-rv5j1201	2616	11	,	,	,
cord-022561-rv5j1201	2616	12	including	include	VBG
cord-022561-rv5j1201	2616	13	several	several	JJ
cord-022561-rv5j1201	2616	14	forms	form	NNS
cord-022561-rv5j1201	2616	15	of	of	IN
cord-022561-rv5j1201	2616	16	cutaneous	cutaneous	JJ
cord-022561-rv5j1201	2616	17	lymphomas	lymphoma	NNS
cord-022561-rv5j1201	2616	18	,	,	,
cord-022561-rv5j1201	2616	19	most	most	RBS
cord-022561-rv5j1201	2616	20	often	often	RB
cord-022561-rv5j1201	2616	21	of	of	IN
cord-022561-rv5j1201	2616	22	T	T	NNP
cord-022561-rv5j1201	2616	23	lymphocyte	lymphocyte	NN
cord-022561-rv5j1201	2616	24	origin	origin	NN
cord-022561-rv5j1201	2616	25	and	and	CC
cord-022561-rv5j1201	2616	26	epitheliotropic	epitheliotropic	NNP
cord-022561-rv5j1201	2616	27	(	(	-LRB-
cord-022561-rv5j1201	2616	28	see	see	VB
cord-022561-rv5j1201	2616	29	Chapter	Chapter	NNP
cord-022561-rv5j1201	2616	30	17	17	CD
cord-022561-rv5j1201	2616	31	)	)	-RRB-
cord-022561-rv5j1201	2616	32	.	.	.
cord-022561-rv5j1201	2617	1	Hepatosplenic	Hepatosplenic	NNP
cord-022561-rv5j1201	2617	2	T	T	NNP
cord-022561-rv5j1201	2617	3	cell	cell	NN
cord-022561-rv5j1201	2617	4	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2617	5	,	,	,
cord-022561-rv5j1201	2617	6	thought	think	VBN
cord-022561-rv5j1201	2617	7	to	to	TO
cord-022561-rv5j1201	2617	8	be	be	VB
cord-022561-rv5j1201	2617	9	of	of	IN
cord-022561-rv5j1201	2617	10	γ	γ	NN
cord-022561-rv5j1201	2617	11	/	/	SYM
cord-022561-rv5j1201	2617	12	δ	δ	NN
cord-022561-rv5j1201	2617	13	T	T	NNP
cord-022561-rv5j1201	2617	14	lymphocyte	lymphocyte	NN
cord-022561-rv5j1201	2617	15	origin	origin	NN
cord-022561-rv5j1201	2617	16	,	,	,
cord-022561-rv5j1201	2617	17	affects	affect	VBZ
cord-022561-rv5j1201	2617	18	the	the	DT
cord-022561-rv5j1201	2617	19	liver	liver	NN
cord-022561-rv5j1201	2617	20	and	and	CC
cord-022561-rv5j1201	2617	21	spleen	spleen	NNS
cord-022561-rv5j1201	2617	22	without	without	IN
cord-022561-rv5j1201	2617	23	significant	significant	JJ
cord-022561-rv5j1201	2617	24	nodal	nodal	JJ
cord-022561-rv5j1201	2617	25	involvement	involvement	NN
cord-022561-rv5j1201	2617	26	.	.	.
cord-022561-rv5j1201	2618	1	Hepatocytotropic	Hepatocytotropic	NNP
cord-022561-rv5j1201	2618	2	T	T	NNP
cord-022561-rv5j1201	2618	3	cell	cell	NN
cord-022561-rv5j1201	2618	4	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2618	5	is	be	VBZ
cord-022561-rv5j1201	2618	6	a	a	DT
cord-022561-rv5j1201	2618	7	distinct	distinct	JJ
cord-022561-rv5j1201	2618	8	form	form	NN
cord-022561-rv5j1201	2618	9	of	of	IN
cord-022561-rv5j1201	2618	10	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2618	11	with	with	IN
cord-022561-rv5j1201	2618	12	tropism	tropism	NN
cord-022561-rv5j1201	2618	13	for	for	IN
cord-022561-rv5j1201	2618	14	the	the	DT
cord-022561-rv5j1201	2618	15	hepatic	hepatic	JJ
cord-022561-rv5j1201	2618	16	cords	cord	NNS
cord-022561-rv5j1201	2618	17	;	;	:
cord-022561-rv5j1201	2618	18	clusters	cluster	NNS
cord-022561-rv5j1201	2618	19	or	or	CC
cord-022561-rv5j1201	2618	20	individual	individual	JJ
cord-022561-rv5j1201	2618	21	neoplastic	neoplastic	JJ
cord-022561-rv5j1201	2618	22	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	2618	23	invade	invade	VBP
cord-022561-rv5j1201	2618	24	the	the	DT
cord-022561-rv5j1201	2618	25	hepatic	hepatic	JJ
cord-022561-rv5j1201	2618	26	cords	cord	NNS
cord-022561-rv5j1201	2618	27	,	,	,
cord-022561-rv5j1201	2618	28	without	without	IN
cord-022561-rv5j1201	2618	29	hepatocyte	hepatocyte	NN
cord-022561-rv5j1201	2618	30	degeneration	degeneration	NN
cord-022561-rv5j1201	2618	31	.	.	.
cord-022561-rv5j1201	2619	1	Intravascular	Intravascular	NNP
cord-022561-rv5j1201	2619	2	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2619	3	is	be	VBZ
cord-022561-rv5j1201	2619	4	a	a	DT
cord-022561-rv5j1201	2619	5	proliferation	proliferation	NN
cord-022561-rv5j1201	2619	6	of	of	IN
cord-022561-rv5j1201	2619	7	large	large	JJ
cord-022561-rv5j1201	2619	8	neoplastic	neoplastic	JJ
cord-022561-rv5j1201	2619	9	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	2619	10	within	within	IN
cord-022561-rv5j1201	2619	11	blood	blood	NN
cord-022561-rv5j1201	2619	12	vessels	vessel	NNS
cord-022561-rv5j1201	2619	13	of	of	IN
cord-022561-rv5j1201	2619	14	many	many	JJ
cord-022561-rv5j1201	2619	15	tissues	tissue	NNS
cord-022561-rv5j1201	2619	16	,	,	,
cord-022561-rv5j1201	2619	17	leading	lead	VBG
cord-022561-rv5j1201	2619	18	to	to	IN
cord-022561-rv5j1201	2619	19	progressive	progressive	JJ
cord-022561-rv5j1201	2619	20	occlusion	occlusion	NN
cord-022561-rv5j1201	2619	21	and	and	CC
cord-022561-rv5j1201	2619	22	subsequent	subsequent	JJ
cord-022561-rv5j1201	2619	23	thromboses	thrombose	NNS
cord-022561-rv5j1201	2619	24	and	and	CC
cord-022561-rv5j1201	2619	25	infarcts	infarct	NNS
cord-022561-rv5j1201	2619	26	.	.	.
cord-022561-rv5j1201	2620	1	This	this	DT
cord-022561-rv5j1201	2620	2	neoplasm	neoplasm	NN
cord-022561-rv5j1201	2620	3	does	do	VBZ
cord-022561-rv5j1201	2620	4	not	not	RB
cord-022561-rv5j1201	2620	5	form	form	VB
cord-022561-rv5j1201	2620	6	an	an	DT
cord-022561-rv5j1201	2620	7	extravascular	extravascular	JJ
cord-022561-rv5j1201	2620	8	mass	mass	NN
cord-022561-rv5j1201	2620	9	,	,	,
cord-022561-rv5j1201	2620	10	and	and	CC
cord-022561-rv5j1201	2620	11	neoplastic	neoplastic	JJ
cord-022561-rv5j1201	2620	12	cells	cell	NNS
cord-022561-rv5j1201	2620	13	are	be	VBP
cord-022561-rv5j1201	2620	14	not	not	RB
cord-022561-rv5j1201	2620	15	found	find	VBN
cord-022561-rv5j1201	2620	16	in	in	IN
cord-022561-rv5j1201	2620	17	peripheral	peripheral	JJ
cord-022561-rv5j1201	2620	18	blood	blood	NN
cord-022561-rv5j1201	2620	19	smears	smear	NNS
cord-022561-rv5j1201	2620	20	or	or	CC
cord-022561-rv5j1201	2620	21	bone	bone	NN
cord-022561-rv5j1201	2620	22	marrow	marrow	NN
cord-022561-rv5j1201	2620	23	.	.	.
cord-022561-rv5j1201	2621	1	Indolent	indolent	JJ
cord-022561-rv5j1201	2621	2	lymphomas	lymphoma	NNS
cord-022561-rv5j1201	2621	3	constitute	constitute	VBP
cord-022561-rv5j1201	2621	4	up	up	IN
cord-022561-rv5j1201	2621	5	to	to	TO
cord-022561-rv5j1201	2621	6	29	29	CD
cord-022561-rv5j1201	2621	7	%	%	NN
cord-022561-rv5j1201	2621	8	of	of	IN
cord-022561-rv5j1201	2621	9	all	all	DT
cord-022561-rv5j1201	2621	10	canine	canine	JJ
cord-022561-rv5j1201	2621	11	lymphomas	lymphoma	NNS
cord-022561-rv5j1201	2621	12	.	.	.
cord-022561-rv5j1201	2622	1	Indolent	indolent	JJ
cord-022561-rv5j1201	2622	2	lymphomas	lymphoma	NNS
cord-022561-rv5j1201	2622	3	in	in	IN
cord-022561-rv5j1201	2622	4	dogs	dog	NNS
cord-022561-rv5j1201	2622	5	,	,	,
cord-022561-rv5j1201	2622	6	in	in	IN
cord-022561-rv5j1201	2622	7	descending	descend	VBG
cord-022561-rv5j1201	2622	8	order	order	NN
cord-022561-rv5j1201	2622	9	of	of	IN
cord-022561-rv5j1201	2622	10	frequency	frequency	NN
cord-022561-rv5j1201	2622	11	,	,	,
cord-022561-rv5j1201	2622	12	include	include	VBP
cord-022561-rv5j1201	2622	13	T	T	NNP
cord-022561-rv5j1201	2622	14	zone	zone	NN
cord-022561-rv5j1201	2622	15	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2622	16	(	(	-LRB-
cord-022561-rv5j1201	2622	17	TZL	TZL	NNP
cord-022561-rv5j1201	2622	18	)	)	-RRB-
cord-022561-rv5j1201	2622	19	,	,	,
cord-022561-rv5j1201	2622	20	marginal	marginal	JJ
cord-022561-rv5j1201	2622	21	zone	zone	NN
cord-022561-rv5j1201	2622	22	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2622	23	(	(	-LRB-
cord-022561-rv5j1201	2622	24	MZL	MZL	NNP
cord-022561-rv5j1201	2622	25	)	)	-RRB-
cord-022561-rv5j1201	2622	26	,	,	,
cord-022561-rv5j1201	2622	27	mantle	mantle	NN
cord-022561-rv5j1201	2622	28	cell	cell	NN
cord-022561-rv5j1201	2622	29	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2622	30	(	(	-LRB-
cord-022561-rv5j1201	2622	31	MCL	MCL	NNP
cord-022561-rv5j1201	2622	32	)	)	-RRB-
cord-022561-rv5j1201	2622	33	,	,	,
cord-022561-rv5j1201	2622	34	and	and	CC
cord-022561-rv5j1201	2622	35	follicular	follicular	JJ
cord-022561-rv5j1201	2622	36	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2622	37	(	(	-LRB-
cord-022561-rv5j1201	2622	38	FL	FL	NNP
cord-022561-rv5j1201	2622	39	)	)	-RRB-
cord-022561-rv5j1201	2622	40	.	.	.
cord-022561-rv5j1201	2623	1	Mantle	mantle	NN
cord-022561-rv5j1201	2623	2	cell	cell	NN
cord-022561-rv5j1201	2623	3	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2623	4	and	and	CC
cord-022561-rv5j1201	2623	5	follicular	follicular	JJ
cord-022561-rv5j1201	2623	6	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2623	7	are	be	VBP
cord-022561-rv5j1201	2623	8	less	less	RBR
cord-022561-rv5j1201	2623	9	commonly	commonly	RB
cord-022561-rv5j1201	2623	10	diagnosed	diagnose	VBN
cord-022561-rv5j1201	2623	11	than	than	IN
cord-022561-rv5j1201	2623	12	T	T	NNP
cord-022561-rv5j1201	2623	13	zone	zone	NN
cord-022561-rv5j1201	2623	14	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2623	15	and	and	CC
cord-022561-rv5j1201	2623	16	marginal	marginal	JJ
cord-022561-rv5j1201	2623	17	zone	zone	NN
cord-022561-rv5j1201	2623	18	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2623	19	;	;	:
cord-022561-rv5j1201	2623	20	therefore	therefore	RB
cord-022561-rv5j1201	2623	21	the	the	DT
cord-022561-rv5j1201	2623	22	reader	reader	NN
cord-022561-rv5j1201	2623	23	is	be	VBZ
cord-022561-rv5j1201	2623	24	referred	refer	VBN
cord-022561-rv5j1201	2623	25	to	to	IN
cord-022561-rv5j1201	2623	26	the	the	DT
cord-022561-rv5j1201	2623	27	Suggested	suggest	VBN
cord-022561-rv5j1201	2623	28	Readings	Readings	NNP
cord-022561-rv5j1201	2623	29	to	to	TO
cord-022561-rv5j1201	2623	30	learn	learn	VB
cord-022561-rv5j1201	2623	31	more	more	RBR
cord-022561-rv5j1201	2623	32	on	on	IN
cord-022561-rv5j1201	2623	33	mantle	mantle	NN
cord-022561-rv5j1201	2623	34	cell	cell	NN
cord-022561-rv5j1201	2623	35	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2623	36	and	and	CC
cord-022561-rv5j1201	2623	37	follicular	follicular	JJ
cord-022561-rv5j1201	2623	38	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2623	39	.	.	.
cord-022561-rv5j1201	2624	1	T	T	NNP
cord-022561-rv5j1201	2624	2	Zone	Zone	NNP
cord-022561-rv5j1201	2624	3	Lymphoma	Lymphoma	NNP
cord-022561-rv5j1201	2624	4	.	.	.
cord-022561-rv5j1201	2625	1	T	T	NNP
cord-022561-rv5j1201	2625	2	zone	zone	NN
cord-022561-rv5j1201	2625	3	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2625	4	is	be	VBZ
cord-022561-rv5j1201	2625	5	the	the	DT
cord-022561-rv5j1201	2625	6	most	most	RBS
cord-022561-rv5j1201	2625	7	common	common	JJ
cord-022561-rv5j1201	2625	8	indolent	indolent	JJ
cord-022561-rv5j1201	2625	9	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2625	10	in	in	IN
cord-022561-rv5j1201	2625	11	dogs	dog	NNS
cord-022561-rv5j1201	2625	12	(	(	-LRB-
cord-022561-rv5j1201	2625	13	Fig	Fig	NNP
cord-022561-rv5j1201	2625	14	.	.	.
cord-022561-rv5j1201	2625	15	13	13	CD
cord-022561-rv5j1201	2625	16	-	-	SYM
cord-022561-rv5j1201	2625	17	93	93	CD
cord-022561-rv5j1201	2625	18	)	)	-RRB-
cord-022561-rv5j1201	2625	19	.	.	.
cord-022561-rv5j1201	2626	1	It	-PRON-	PRP
cord-022561-rv5j1201	2626	2	presents	present	VBZ
cord-022561-rv5j1201	2626	3	as	as	IN
cord-022561-rv5j1201	2626	4	a	a	DT
cord-022561-rv5j1201	2626	5	solitary	solitary	JJ
cord-022561-rv5j1201	2626	6	or	or	CC
cord-022561-rv5j1201	2626	7	varies	vary	VBZ
cord-022561-rv5j1201	2626	8	based	base	VBN
cord-022561-rv5j1201	2626	9	on	on	IN
cord-022561-rv5j1201	2626	10	the	the	DT
cord-022561-rv5j1201	2626	11	study	study	NN
cord-022561-rv5j1201	2626	12	and	and	CC
cord-022561-rv5j1201	2626	13	the	the	DT
cord-022561-rv5j1201	2626	14	grade	grade	NN
cord-022561-rv5j1201	2626	15	of	of	IN
cord-022561-rv5j1201	2626	16	the	the	DT
cord-022561-rv5j1201	2626	17	tumor	tumor	NN
cord-022561-rv5j1201	2626	18	(	(	-LRB-
cord-022561-rv5j1201	2626	19	as	as	IN
cord-022561-rv5j1201	2626	20	determined	determine	VBN
cord-022561-rv5j1201	2626	21	by	by	IN
cord-022561-rv5j1201	2626	22	mitotic	mitotic	JJ
cord-022561-rv5j1201	2626	23	figures	figure	NNS
cord-022561-rv5j1201	2626	24	)	)	-RRB-
cord-022561-rv5j1201	2626	25	.	.	.
cord-022561-rv5j1201	2627	1	Peripheral	peripheral	JJ
cord-022561-rv5j1201	2627	2	T	T	NNP
cord-022561-rv5j1201	2627	3	cell	cell	NN
cord-022561-rv5j1201	2627	4	lymphomas	lymphoma	NNS
cord-022561-rv5j1201	2627	5	-	-	:
cord-022561-rv5j1201	2627	6	not	not	RB
cord-022561-rv5j1201	2627	7	otherwise	otherwise	RB
cord-022561-rv5j1201	2627	8	specified	specify	VBN
cord-022561-rv5j1201	2627	9	are	be	VBP
cord-022561-rv5j1201	2627	10	the	the	DT
cord-022561-rv5j1201	2627	11	second	second	JJ
cord-022561-rv5j1201	2627	12	most	most	RBS
cord-022561-rv5j1201	2627	13	common	common	JJ
cord-022561-rv5j1201	2627	14	subtype	subtype	NN
cord-022561-rv5j1201	2627	15	in	in	IN
cord-022561-rv5j1201	2627	16	dogs	dog	NNS
cord-022561-rv5j1201	2627	17	.	.	.
cord-022561-rv5j1201	2628	1	This	this	DT
cord-022561-rv5j1201	2628	2	category	category	NN
cord-022561-rv5j1201	2628	3	includes	include	VBZ
cord-022561-rv5j1201	2628	4	all	all	DT
cord-022561-rv5j1201	2628	5	T	T	NNP
cord-022561-rv5j1201	2628	6	cell	cell	NN
cord-022561-rv5j1201	2628	7	lymphomas	lymphoma	NNS
cord-022561-rv5j1201	2628	8	that	that	WDT
cord-022561-rv5j1201	2628	9	do	do	VBP
cord-022561-rv5j1201	2628	10	not	not	RB
cord-022561-rv5j1201	2628	11	fit	fit	VB
cord-022561-rv5j1201	2628	12	into	into	IN
cord-022561-rv5j1201	2628	13	the	the	DT
cord-022561-rv5j1201	2628	14	other	other	JJ
cord-022561-rv5j1201	2628	15	categories	category	NNS
cord-022561-rv5j1201	2628	16	(	(	-LRB-
cord-022561-rv5j1201	2628	17	e.g.	e.g.	RB
cord-022561-rv5j1201	2628	18	,	,	,
cord-022561-rv5j1201	2628	19	T	T	NNP
cord-022561-rv5j1201	2628	20	zone	zone	NN
cord-022561-rv5j1201	2628	21	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2628	22	,	,	,
cord-022561-rv5j1201	2628	23	enteropathy	enteropathy	NNP
cord-022561-rv5j1201	2628	24	-	-	HYPH
cord-022561-rv5j1201	2628	25	associated	associate	VBN
cord-022561-rv5j1201	2628	26	T	T	NNP
cord-022561-rv5j1201	2628	27	cell	cell	NN
cord-022561-rv5j1201	2628	28	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2628	29	,	,	,
cord-022561-rv5j1201	2628	30	and	and	CC
cord-022561-rv5j1201	2628	31	hepatosplenic	hepatosplenic	NNP
cord-022561-rv5j1201	2628	32	T	T	NNP
cord-022561-rv5j1201	2628	33	cell	cell	NN
cord-022561-rv5j1201	2628	34	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2628	35	)	)	-RRB-
cord-022561-rv5j1201	2628	36	.	.	.
cord-022561-rv5j1201	2629	1	Peripheral	peripheral	JJ
cord-022561-rv5j1201	2629	2	T	T	NNP
cord-022561-rv5j1201	2629	3	cell	cell	NN
cord-022561-rv5j1201	2629	4	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2629	5	also	also	RB
cord-022561-rv5j1201	2629	6	effaces	efface	VBZ
cord-022561-rv5j1201	2629	7	nodal	nodal	JJ
cord-022561-rv5j1201	2629	8	architecture	architecture	NN
cord-022561-rv5j1201	2629	9	,	,	,
cord-022561-rv5j1201	2629	10	and	and	CC
cord-022561-rv5j1201	2629	11	when	when	WRB
cord-022561-rv5j1201	2629	12	compared	compare	VBN
cord-022561-rv5j1201	2629	13	to	to	TO
cord-022561-rv5j1201	2629	14	diffuse	diffuse	VB
cord-022561-rv5j1201	2629	15	large	large	JJ
cord-022561-rv5j1201	2629	16	B	b	NN
cord-022561-rv5j1201	2629	17	cell	cell	NN
cord-022561-rv5j1201	2629	18	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2629	19	,	,	,
cord-022561-rv5j1201	2629	20	there	there	EX
cord-022561-rv5j1201	2629	21	is	be	VBZ
cord-022561-rv5j1201	2629	22	more	more	JJR
cord-022561-rv5j1201	2629	23	variation	variation	NN
cord-022561-rv5j1201	2629	24	in	in	IN
cord-022561-rv5j1201	2629	25	nuclear	nuclear	JJ
cord-022561-rv5j1201	2629	26	size	size	NN
cord-022561-rv5j1201	2629	27	and	and	CC
cord-022561-rv5j1201	2629	28	morphologic	morphologic	JJ
cord-022561-rv5j1201	2629	29	features	feature	NNS
cord-022561-rv5j1201	2629	30	.	.	.
cord-022561-rv5j1201	2630	1	Dogs	dog	NNS
cord-022561-rv5j1201	2630	2	with	with	IN
cord-022561-rv5j1201	2630	3	this	this	DT
cord-022561-rv5j1201	2630	4	subtype	subtype	NN
cord-022561-rv5j1201	2630	5	tend	tend	VBP
cord-022561-rv5j1201	2630	6	to	to	TO
cord-022561-rv5j1201	2630	7	have	have	VB
cord-022561-rv5j1201	2630	8	shorter	short	JJR
cord-022561-rv5j1201	2630	9	survival	survival	NN
cord-022561-rv5j1201	2630	10	times	time	NNS
cord-022561-rv5j1201	2630	11	.	.	.
cord-022561-rv5j1201	2631	1	Intermediate	intermediate	JJ
cord-022561-rv5j1201	2631	2	cell	cell	NN
cord-022561-rv5j1201	2631	3	size	size	NN
cord-022561-rv5j1201	2631	4	,	,	,
cord-022561-rv5j1201	2631	5	high	high	JJ
cord-022561-rv5j1201	2631	6	-	-	HYPH
cord-022561-rv5j1201	2631	7	grade	grade	NN
cord-022561-rv5j1201	2631	8	lymphomas	lymphoma	NNS
cord-022561-rv5j1201	2631	9	are	be	VBP
cord-022561-rv5j1201	2631	10	less	less	RBR
cord-022561-rv5j1201	2631	11	common	common	JJ
cord-022561-rv5j1201	2631	12	in	in	IN
cord-022561-rv5j1201	2631	13	dogs	dog	NNS
cord-022561-rv5j1201	2631	14	,	,	,
cord-022561-rv5j1201	2631	15	and	and	CC
cord-022561-rv5j1201	2631	16	the	the	DT
cord-022561-rv5j1201	2631	17	two	two	CD
cord-022561-rv5j1201	2631	18	most	most	RBS
cord-022561-rv5j1201	2631	19	frequently	frequently	RB
cord-022561-rv5j1201	2631	20	encountered	encounter	VBN
cord-022561-rv5j1201	2631	21	subtypes	subtype	NNS
cord-022561-rv5j1201	2631	22	are	be	VBP
cord-022561-rv5j1201	2631	23	lymphoblastic	lymphoblastic	JJ
cord-022561-rv5j1201	2631	24	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2631	25	(	(	-LRB-
cord-022561-rv5j1201	2631	26	LBL	LBL	NNP
cord-022561-rv5j1201	2631	27	)	)	-RRB-
cord-022561-rv5j1201	2631	28	and	and	CC
cord-022561-rv5j1201	2631	29	Burkitt	Burkitt	NNP
cord-022561-rv5j1201	2631	30	-	-	HYPH
cord-022561-rv5j1201	2631	31	like	like	JJ
cord-022561-rv5j1201	2631	32	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2631	33	(	(	-LRB-
cord-022561-rv5j1201	2631	34	BLL	BLL	NNP
cord-022561-rv5j1201	2631	35	)	)	-RRB-
cord-022561-rv5j1201	2631	36	.	.	.
cord-022561-rv5j1201	2632	1	Lymphoblastic	Lymphoblastic	NNP
cord-022561-rv5j1201	2632	2	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2632	3	may	may	MD
cord-022561-rv5j1201	2632	4	be	be	VB
cord-022561-rv5j1201	2632	5	of	of	IN
cord-022561-rv5j1201	2632	6	B	B	NNP
cord-022561-rv5j1201	2632	7	or	or	CC
cord-022561-rv5j1201	2632	8	T	t	NN
cord-022561-rv5j1201	2632	9	lymphocyte	lymphocyte	NN
cord-022561-rv5j1201	2632	10	origin	origin	NN
cord-022561-rv5j1201	2632	11	,	,	,
cord-022561-rv5j1201	2632	12	though	though	IN
cord-022561-rv5j1201	2632	13	T	T	NNP
cord-022561-rv5j1201	2632	14	cell	cell	NN
cord-022561-rv5j1201	2632	15	lymphoblastic	lymphoblastic	NN
cord-022561-rv5j1201	2632	16	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2632	17	is	be	VBZ
cord-022561-rv5j1201	2632	18	more	more	RBR
cord-022561-rv5j1201	2632	19	common	common	JJ
cord-022561-rv5j1201	2632	20	of	of	IN
cord-022561-rv5j1201	2632	21	the	the	DT
cord-022561-rv5j1201	2632	22	two	two	CD
cord-022561-rv5j1201	2632	23	.	.	.
cord-022561-rv5j1201	2633	1	It	-PRON-	PRP
cord-022561-rv5j1201	2633	2	is	be	VBZ
cord-022561-rv5j1201	2633	3	important	important	JJ
cord-022561-rv5j1201	2633	4	to	to	TO
cord-022561-rv5j1201	2633	5	recognize	recognize	VB
cord-022561-rv5j1201	2633	6	a	a	DT
cord-022561-rv5j1201	2633	7	common	common	JJ
cord-022561-rv5j1201	2633	8	misuse	misuse	NN
cord-022561-rv5j1201	2633	9	of	of	IN
cord-022561-rv5j1201	2633	10	the	the	DT
cord-022561-rv5j1201	2633	11	term	term	NN
cord-022561-rv5j1201	2633	12	"	"	``
cord-022561-rv5j1201	2633	13	lymphoblast	lymphoblast	NN
cord-022561-rv5j1201	2633	14	"	"	''
cord-022561-rv5j1201	2633	15	in	in	IN
cord-022561-rv5j1201	2633	16	lymphoblastic	lymphoblastic	JJ
cord-022561-rv5j1201	2633	17	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2633	18	-	-	HYPH
cord-022561-rv5j1201	2633	19	by	by	IN
cord-022561-rv5j1201	2633	20	definition	definition	NN
cord-022561-rv5j1201	2633	21	in	in	IN
cord-022561-rv5j1201	2633	22	lymphoblastic	lymphoblastic	JJ
cord-022561-rv5j1201	2633	23	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2633	24	,	,	,
cord-022561-rv5j1201	2633	25	lymphoblasts	lymphoblast	NNS
cord-022561-rv5j1201	2633	26	are	be	VBP
cord-022561-rv5j1201	2633	27	intermediate	intermediate	JJ
cord-022561-rv5j1201	2633	28	-	-	HYPH
cord-022561-rv5j1201	2633	29	sized	sized	JJ
cord-022561-rv5j1201	2633	30	cells	cell	NNS
cord-022561-rv5j1201	2633	31	with	with	IN
cord-022561-rv5j1201	2633	32	a	a	DT
cord-022561-rv5j1201	2633	33	distinct	distinct	JJ
cord-022561-rv5j1201	2633	34	dispersed	disperse	VBN
cord-022561-rv5j1201	2633	35	chromatin	chromatin	NN
cord-022561-rv5j1201	2633	36	pattern	pattern	NN
cord-022561-rv5j1201	2633	37	,	,	,
cord-022561-rv5j1201	2633	38	and	and	CC
cord-022561-rv5j1201	2633	39	not	not	RB
cord-022561-rv5j1201	2633	40	the	the	DT
cord-022561-rv5j1201	2633	41	large	large	JJ
cord-022561-rv5j1201	2633	42	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	2633	43	seen	see	VBN
cord-022561-rv5j1201	2633	44	in	in	IN
cord-022561-rv5j1201	2633	45	cases	case	NNS
cord-022561-rv5j1201	2633	46	of	of	IN
cord-022561-rv5j1201	2633	47	diffuse	diffuse	VB
cord-022561-rv5j1201	2633	48	large	large	JJ
cord-022561-rv5j1201	2633	49	B	b	NN
cord-022561-rv5j1201	2633	50	cell	cell	NN
cord-022561-rv5j1201	2633	51	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2633	52	or	or	CC
cord-022561-rv5j1201	2633	53	peripheral	peripheral	JJ
cord-022561-rv5j1201	2633	54	T	T	NNP
cord-022561-rv5j1201	2633	55	cell	cell	NN
cord-022561-rv5j1201	2633	56	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2633	57	.	.	.
cord-022561-rv5j1201	2634	1	T	T	NNP
cord-022561-rv5j1201	2634	2	lymphocyte	lymphocyte	NN
cord-022561-rv5j1201	2634	3	lymphoblastic	lymphoblastic	NN
cord-022561-rv5j1201	2634	4	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2634	5	is	be	VBZ
cord-022561-rv5j1201	2634	6	an	an	DT
cord-022561-rv5j1201	2634	7	aggressive	aggressive	JJ
cord-022561-rv5j1201	2634	8	disease	disease	NN
cord-022561-rv5j1201	2634	9	that	that	WDT
cord-022561-rv5j1201	2634	10	is	be	VBZ
cord-022561-rv5j1201	2634	11	often	often	RB
cord-022561-rv5j1201	2634	12	resistant	resistant	JJ
cord-022561-rv5j1201	2634	13	to	to	IN
cord-022561-rv5j1201	2634	14	treatment	treatment	NN
cord-022561-rv5j1201	2634	15	.	.	.
cord-022561-rv5j1201	2635	1	Burkitt	Burkitt	NNP
cord-022561-rv5j1201	2635	2	-	-	HYPH
cord-022561-rv5j1201	2635	3	like	like	JJ
cord-022561-rv5j1201	2635	4	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2635	5	is	be	VBZ
cord-022561-rv5j1201	2635	6	a	a	DT
cord-022561-rv5j1201	2635	7	high	high	JJ
cord-022561-rv5j1201	2635	8	-	-	HYPH
cord-022561-rv5j1201	2635	9	grade	grade	NN
cord-022561-rv5j1201	2635	10	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2635	11	of	of	IN
cord-022561-rv5j1201	2635	12	B	b	NN
cord-022561-rv5j1201	2635	13	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	2635	14	.	.	.
cord-022561-rv5j1201	2636	1	Consequently	consequently	RB
cord-022561-rv5j1201	2636	2	there	there	EX
cord-022561-rv5j1201	2636	3	is	be	VBZ
cord-022561-rv5j1201	2636	4	marked	mark	VBN
cord-022561-rv5j1201	2636	5	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	2636	6	atrophy	atrophy	NN
cord-022561-rv5j1201	2636	7	of	of	IN
cord-022561-rv5j1201	2636	8	thymus	thymus	NN
cord-022561-rv5j1201	2636	9	,	,	,
cord-022561-rv5j1201	2636	10	spleen	spleen	NNS
cord-022561-rv5j1201	2636	11	,	,	,
cord-022561-rv5j1201	2636	12	lymph	lymph	NN
cord-022561-rv5j1201	2636	13	node	node	NN
cord-022561-rv5j1201	2636	14	,	,	,
cord-022561-rv5j1201	2636	15	and	and	CC
cord-022561-rv5j1201	2636	16	MALT	malt	NN
cord-022561-rv5j1201	2636	17	(	(	-LRB-
cord-022561-rv5j1201	2636	18	particularly	particularly	RB
cord-022561-rv5j1201	2636	19	Peyer	Peyer	NNP
cord-022561-rv5j1201	2636	20	's	's	POS
cord-022561-rv5j1201	2636	21	patches	patch	NNS
cord-022561-rv5j1201	2636	22	)	)	-RRB-
cord-022561-rv5j1201	2636	23	.	.	.
cord-022561-rv5j1201	2637	1	See	see	VB
cord-022561-rv5j1201	2637	2	Bone	Bone	NNP
cord-022561-rv5j1201	2637	3	Marrow	Marrow	NNP
cord-022561-rv5j1201	2637	4	and	and	CC
cord-022561-rv5j1201	2637	5	Blood	blood	NN
cord-022561-rv5j1201	2637	6	Cells	cell	NNS
cord-022561-rv5j1201	2637	7	,	,	,
cord-022561-rv5j1201	2637	8	Disorders	disorder	NNS
cord-022561-rv5j1201	2637	9	of	of	IN
cord-022561-rv5j1201	2637	10	Domestic	domestic	JJ
cord-022561-rv5j1201	2637	11	Animals	Animals	NNPS
cord-022561-rv5j1201	2637	12	,	,	,
cord-022561-rv5j1201	2637	13	Types	type	NNS
cord-022561-rv5j1201	2637	14	of	of	IN
cord-022561-rv5j1201	2637	15	Hematopoietic	Hematopoietic	NNP
cord-022561-rv5j1201	2637	16	Neoplasia	Neoplasia	NNP
cord-022561-rv5j1201	2637	17	,	,	,
cord-022561-rv5j1201	2637	18	Myeloid	Myeloid	NNP
cord-022561-rv5j1201	2637	19	Neoplasia	Neoplasia	NNP
cord-022561-rv5j1201	2637	20	,	,	,
cord-022561-rv5j1201	2637	21	Mast	Mast	NNP
cord-022561-rv5j1201	2637	22	Cell	Cell	NNP
cord-022561-rv5j1201	2637	23	Neoplasia	Neoplasia	NNP
cord-022561-rv5j1201	2637	24	and	and	CC
cord-022561-rv5j1201	2637	25	see	see	VB
cord-022561-rv5j1201	2637	26	E-	E-	NNP
cord-022561-rv5j1201	2637	27	Fig	Fig	NNP
cord-022561-rv5j1201	2637	28	.	.	.
cord-022561-rv5j1201	2638	1	13	13	CD
cord-022561-rv5j1201	2638	2	-	-	SYM
cord-022561-rv5j1201	2638	3	6	6	CD
cord-022561-rv5j1201	2638	4	.	.	.
cord-022561-rv5j1201	2639	1	Lymphoma	Lymphoma	NNP
cord-022561-rv5j1201	2639	2	is	be	VBZ
cord-022561-rv5j1201	2639	3	the	the	DT
cord-022561-rv5j1201	2639	4	most	most	RBS
cord-022561-rv5j1201	2639	5	commonly	commonly	RB
cord-022561-rv5j1201	2639	6	diagnosed	diagnose	VBN
cord-022561-rv5j1201	2639	7	neoplasm	neoplasm	NN
cord-022561-rv5j1201	2639	8	in	in	IN
cord-022561-rv5j1201	2639	9	cats	cat	NNS
cord-022561-rv5j1201	2639	10	,	,	,
cord-022561-rv5j1201	2639	11	and	and	CC
cord-022561-rv5j1201	2639	12	the	the	DT
cord-022561-rv5j1201	2639	13	incidence	incidence	NN
cord-022561-rv5j1201	2639	14	is	be	VBZ
cord-022561-rv5j1201	2639	15	reportedly	reportedly	RB
cord-022561-rv5j1201	2639	16	the	the	DT
cord-022561-rv5j1201	2639	17	highest	high	JJS
cord-022561-rv5j1201	2639	18	for	for	IN
cord-022561-rv5j1201	2639	19	any	any	DT
cord-022561-rv5j1201	2639	20	species	specie	NNS
cord-022561-rv5j1201	2639	21	.	.	.
cord-022561-rv5j1201	2640	1	Mediastinal	Mediastinal	NNP
cord-022561-rv5j1201	2640	2	or	or	CC
cord-022561-rv5j1201	2640	3	multicentric	multicentric	JJ
cord-022561-rv5j1201	2640	4	lymphomas	lymphoma	NNS
cord-022561-rv5j1201	2640	5	are	be	VBP
cord-022561-rv5j1201	2640	6	seen	see	VBN
cord-022561-rv5j1201	2640	7	in	in	IN
cord-022561-rv5j1201	2640	8	young	young	JJ
cord-022561-rv5j1201	2640	9	,	,	,
cord-022561-rv5j1201	2640	10	FeLV	felv	NN
cord-022561-rv5j1201	2640	11	-	-	HYPH
cord-022561-rv5j1201	2640	12	infected	infect	VBN
cord-022561-rv5j1201	2640	13	cats	cat	NNS
cord-022561-rv5j1201	2640	14	(	(	-LRB-
cord-022561-rv5j1201	2640	15	see	see	VB
cord-022561-rv5j1201	2640	16	Fig	Fig	NNP
cord-022561-rv5j1201	2640	17	.	.	.
cord-022561-rv5j1201	2641	1	13	13	CD
cord-022561-rv5j1201	2641	2	-53	-53	NNP
cord-022561-rv5j1201	2641	3	)	)	-RRB-
cord-022561-rv5j1201	2642	1	.	.	.
cord-022561-rv5j1201	2643	1	With	with	IN
cord-022561-rv5j1201	2643	2	the	the	DT
cord-022561-rv5j1201	2643	3	advent	advent	NN
cord-022561-rv5j1201	2643	4	of	of	IN
cord-022561-rv5j1201	2643	5	FeLV	FeLV	NNP
cord-022561-rv5j1201	2643	6	vaccine	vaccine	NN
cord-022561-rv5j1201	2643	7	and	and	CC
cord-022561-rv5j1201	2643	8	routine	routine	JJ
cord-022561-rv5j1201	2643	9	testing	testing	NN
cord-022561-rv5j1201	2643	10	,	,	,
cord-022561-rv5j1201	2643	11	the	the	DT
cord-022561-rv5j1201	2643	12	prevalence	prevalence	NN
cord-022561-rv5j1201	2643	13	of	of	IN
cord-022561-rv5j1201	2643	14	FeLV	FeLV	NNP
cord-022561-rv5j1201	2643	15	-	-	HYPH
cord-022561-rv5j1201	2643	16	associated	associate	VBN
cord-022561-rv5j1201	2643	17	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2643	18	is	be	VBZ
cord-022561-rv5j1201	2643	19	decreased	decrease	VBN
cord-022561-rv5j1201	2643	20	.	.	.
cord-022561-rv5j1201	2644	1	Currently	currently	RB
cord-022561-rv5j1201	2644	2	the	the	DT
cord-022561-rv5j1201	2644	3	alimentary	alimentary	JJ
cord-022561-rv5j1201	2644	4	tract	tract	NN
cord-022561-rv5j1201	2644	5	is	be	VBZ
cord-022561-rv5j1201	2644	6	the	the	DT
cord-022561-rv5j1201	2644	7	most	most	RBS
cord-022561-rv5j1201	2644	8	commonly	commonly	RB
cord-022561-rv5j1201	2644	9	affected	affect	VBN
cord-022561-rv5j1201	2644	10	site	site	NN
cord-022561-rv5j1201	2644	11	,	,	,
cord-022561-rv5j1201	2644	12	and	and	CC
cord-022561-rv5j1201	2644	13	typically	typically	RB
cord-022561-rv5j1201	2644	14	occurs	occur	VBZ
cord-022561-rv5j1201	2644	15	in	in	IN
cord-022561-rv5j1201	2644	16	cats	cat	NNS
cord-022561-rv5j1201	2644	17	greater	great	JJR
cord-022561-rv5j1201	2644	18	than	than	IN
cord-022561-rv5j1201	2644	19	10	10	CD
cord-022561-rv5j1201	2644	20	years	year	NNS
cord-022561-rv5j1201	2644	21	of	of	IN
cord-022561-rv5j1201	2644	22	age	age	NN
cord-022561-rv5j1201	2644	23	.	.	.
cord-022561-rv5j1201	2645	1	Other	other	JJ
cord-022561-rv5j1201	2645	2	miscellaneous	miscellaneous	JJ
cord-022561-rv5j1201	2645	3	sites	site	NNS
cord-022561-rv5j1201	2645	4	commonly	commonly	RB
cord-022561-rv5j1201	2645	5	affected	affect	VBN
cord-022561-rv5j1201	2645	6	are	be	VBP
cord-022561-rv5j1201	2645	7	brain	brain	NN
cord-022561-rv5j1201	2645	8	,	,	,
cord-022561-rv5j1201	2645	9	spinal	spinal	JJ
cord-022561-rv5j1201	2645	10	cord	cord	NN
cord-022561-rv5j1201	2645	11	,	,	,
cord-022561-rv5j1201	2645	12	eye	eye	NN
cord-022561-rv5j1201	2645	13	,	,	,
cord-022561-rv5j1201	2645	14	kidney	kidney	NN
cord-022561-rv5j1201	2645	15	,	,	,
cord-022561-rv5j1201	2645	16	and	and	CC
cord-022561-rv5j1201	2645	17	nasopharynx	nasopharynx	NN
cord-022561-rv5j1201	2645	18	.	.	.
cord-022561-rv5j1201	2646	1	The	the	DT
cord-022561-rv5j1201	2646	2	retrovirus	retrovirus	NN
cord-022561-rv5j1201	2646	3	FeLV	FeLV	NNP
cord-022561-rv5j1201	2646	4	has	have	VBZ
cord-022561-rv5j1201	2646	5	long	long	RB
cord-022561-rv5j1201	2646	6	been	be	VBN
cord-022561-rv5j1201	2646	7	recognized	recognize	VBN
cord-022561-rv5j1201	2646	8	as	as	IN
cord-022561-rv5j1201	2646	9	a	a	DT
cord-022561-rv5j1201	2646	10	cause	cause	NN
cord-022561-rv5j1201	2646	11	of	of	IN
cord-022561-rv5j1201	2646	12	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2646	13	in	in	IN
cord-022561-rv5j1201	2646	14	cats	cat	NNS
cord-022561-rv5j1201	2646	15	-	-	:
cord-022561-rv5j1201	2646	16	the	the	DT
cord-022561-rv5j1201	2646	17	risk	risk	NN
cord-022561-rv5j1201	2646	18	for	for	IN
cord-022561-rv5j1201	2646	19	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2646	20	is	be	VBZ
cord-022561-rv5j1201	2646	21	increased	increase	VBN
cord-022561-rv5j1201	2646	22	sixtyfold	sixtyfold	NN
cord-022561-rv5j1201	2646	23	in	in	IN
cord-022561-rv5j1201	2646	24	infected	infected	JJ
cord-022561-rv5j1201	2646	25	cats	cat	NNS
cord-022561-rv5j1201	2646	26	.	.	.
cord-022561-rv5j1201	2647	1	Before	before	IN
cord-022561-rv5j1201	2647	2	the	the	DT
cord-022561-rv5j1201	2647	3	advent	advent	NN
cord-022561-rv5j1201	2647	4	of	of	IN
cord-022561-rv5j1201	2647	5	a	a	DT
cord-022561-rv5j1201	2647	6	vaccine	vaccine	NN
cord-022561-rv5j1201	2647	7	in	in	IN
cord-022561-rv5j1201	2647	8	1985	1985	CD
cord-022561-rv5j1201	2647	9	,	,	,
cord-022561-rv5j1201	2647	10	approximately	approximately	RB
cord-022561-rv5j1201	2647	11	70	70	CD
cord-022561-rv5j1201	2647	12	%	%	NN
cord-022561-rv5j1201	2647	13	of	of	IN
cord-022561-rv5j1201	2647	14	cats	cat	NNS
cord-022561-rv5j1201	2647	15	(	(	-LRB-
cord-022561-rv5j1201	2647	16	mainly	mainly	RB
cord-022561-rv5j1201	2647	17	young	young	JJ
cord-022561-rv5j1201	2647	18	animals	animal	NNS
cord-022561-rv5j1201	2647	19	)	)	-RRB-
cord-022561-rv5j1201	2647	20	with	with	IN
cord-022561-rv5j1201	2647	21	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2647	22	were	be	VBD
cord-022561-rv5j1201	2647	23	FeLV	FeLV	NNP
cord-022561-rv5j1201	2647	24	positive	positive	JJ
cord-022561-rv5j1201	2647	25	.	.	.
cord-022561-rv5j1201	2648	1	FeLV	FeLV	NNP
cord-022561-rv5j1201	2648	2	infects	infect	VBZ
cord-022561-rv5j1201	2648	3	T	t	NN
cord-022561-rv5j1201	2648	4	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	2648	5	and	and	CC
cord-022561-rv5j1201	2648	6	can	can	MD
cord-022561-rv5j1201	2648	7	cause	cause	VB
cord-022561-rv5j1201	2648	8	myelodysplastic	myelodysplastic	JJ
cord-022561-rv5j1201	2648	9	syndrome	syndrome	NN
cord-022561-rv5j1201	2648	10	,	,	,
cord-022561-rv5j1201	2648	11	acute	acute	JJ
cord-022561-rv5j1201	2648	12	myeloid	myeloid	NN
cord-022561-rv5j1201	2648	13	leukemias	leukemia	NNS
cord-022561-rv5j1201	2648	14	(	(	-LRB-
cord-022561-rv5j1201	2648	15	see	see	VB
cord-022561-rv5j1201	2648	16	Myeloid	Myeloid	NNP
cord-022561-rv5j1201	2648	17	Neoplasia	Neoplasia	NNP
cord-022561-rv5j1201	2648	18	)	)	-RRB-
cord-022561-rv5j1201	2648	19	,	,	,
cord-022561-rv5j1201	2648	20	and	and	CC
cord-022561-rv5j1201	2648	21	T	T	NNP
cord-022561-rv5j1201	2648	22	lymphocyte	lymphocyte	NN
cord-022561-rv5j1201	2648	23	leukemia	leukemia	NN
cord-022561-rv5j1201	2648	24	/	/	SYM
cord-022561-rv5j1201	2648	25	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2648	26	.	.	.
cord-022561-rv5j1201	2649	1	In	in	IN
cord-022561-rv5j1201	2649	2	the	the	DT
cord-022561-rv5j1201	2649	3	latter	latter	JJ
cord-022561-rv5j1201	2649	4	the	the	DT
cord-022561-rv5j1201	2649	5	mediastinum	mediastinum	NNS
cord-022561-rv5j1201	2649	6	(	(	-LRB-
cord-022561-rv5j1201	2649	7	thymus	thymus	NN
cord-022561-rv5j1201	2649	8	,	,	,
cord-022561-rv5j1201	2649	9	mediastinal	mediastinal	JJ
cord-022561-rv5j1201	2649	10	,	,	,
cord-022561-rv5j1201	2649	11	and	and	CC
cord-022561-rv5j1201	2649	12	sternal	sternal	JJ
cord-022561-rv5j1201	2649	13	lymph	lymph	NN
cord-022561-rv5j1201	2649	14	nodes	node	NNS
cord-022561-rv5j1201	2649	15	)	)	-RRB-
cord-022561-rv5j1201	2649	16	is	be	VBZ
cord-022561-rv5j1201	2649	17	the	the	DT
cord-022561-rv5j1201	2649	18	site	site	NN
cord-022561-rv5j1201	2649	19	most	most	RBS
cord-022561-rv5j1201	2649	20	commonly	commonly	RB
cord-022561-rv5j1201	2649	21	involved	involve	VBN
cord-022561-rv5j1201	2649	22	,	,	,
cord-022561-rv5j1201	2649	23	although	although	IN
cord-022561-rv5j1201	2649	24	a	a	DT
cord-022561-rv5j1201	2649	25	multicentric	multicentric	JJ
cord-022561-rv5j1201	2649	26	distribution	distribution	NN
cord-022561-rv5j1201	2649	27	also	also	RB
cord-022561-rv5j1201	2649	28	occurs	occur	VBZ
cord-022561-rv5j1201	2649	29	.	.	.
cord-022561-rv5j1201	2650	1	Routine	routine	JJ
cord-022561-rv5j1201	2650	2	FeLV	felv	NN
cord-022561-rv5j1201	2650	3	vaccination	vaccination	NN
cord-022561-rv5j1201	2650	4	has	have	VBZ
cord-022561-rv5j1201	2650	5	led	lead	VBN
cord-022561-rv5j1201	2650	6	to	to	IN
cord-022561-rv5j1201	2650	7	a	a	DT
cord-022561-rv5j1201	2650	8	significant	significant	JJ
cord-022561-rv5j1201	2650	9	decrease	decrease	NN
cord-022561-rv5j1201	2650	10	in	in	IN
cord-022561-rv5j1201	2650	11	the	the	DT
cord-022561-rv5j1201	2650	12	prevalence	prevalence	NN
cord-022561-rv5j1201	2650	13	of	of	IN
cord-022561-rv5j1201	2650	14	FeLV	FeLV	NNP
cord-022561-rv5j1201	2650	15	infection	infection	NN
cord-022561-rv5j1201	2650	16	,	,	,
cord-022561-rv5j1201	2650	17	which	which	WDT
cord-022561-rv5j1201	2650	18	has	have	VBZ
cord-022561-rv5j1201	2650	19	resulted	result	VBN
cord-022561-rv5j1201	2650	20	in	in	IN
cord-022561-rv5j1201	2650	21	a	a	DT
cord-022561-rv5j1201	2650	22	decrease	decrease	NN
cord-022561-rv5j1201	2650	23	in	in	IN
cord-022561-rv5j1201	2650	24	the	the	DT
cord-022561-rv5j1201	2650	25	proportion	proportion	NN
cord-022561-rv5j1201	2650	26	of	of	IN
cord-022561-rv5j1201	2650	27	mediastinal	mediastinal	JJ
cord-022561-rv5j1201	2650	28	lymphomas	lymphoma	NNS
cord-022561-rv5j1201	2650	29	.	.	.
cord-022561-rv5j1201	2651	1	The	the	DT
cord-022561-rv5j1201	2651	2	risk	risk	NN
cord-022561-rv5j1201	2651	3	for	for	IN
cord-022561-rv5j1201	2651	4	developing	develop	VBG
cord-022561-rv5j1201	2651	5	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2651	6	in	in	IN
cord-022561-rv5j1201	2651	7	FIV	fiv	NN
cord-022561-rv5j1201	2651	8	-	-	HYPH
cord-022561-rv5j1201	2651	9	infected	infect	VBN
cord-022561-rv5j1201	2651	10	cats	cat	NNS
cord-022561-rv5j1201	2651	11	is	be	VBZ
cord-022561-rv5j1201	2651	12	fivefold	fivefold	JJ
cord-022561-rv5j1201	2651	13	to	to	TO
cord-022561-rv5j1201	2651	14	sixfold	sixfold	VB
cord-022561-rv5j1201	2651	15	higher	high	JJR
cord-022561-rv5j1201	2651	16	than	than	IN
cord-022561-rv5j1201	2651	17	in	in	IN
cord-022561-rv5j1201	2651	18	uninfected	uninfected	JJ
cord-022561-rv5j1201	2651	19	cats	cat	NNS
cord-022561-rv5j1201	2651	20	.	.	.
cord-022561-rv5j1201	2652	1	Cats	cat	NNS
cord-022561-rv5j1201	2652	2	that	that	WDT
cord-022561-rv5j1201	2652	3	underwent	undergo	VBD
cord-022561-rv5j1201	2652	4	kidney	kidney	NN
cord-022561-rv5j1201	2652	5	transplantation	transplantation	NN
cord-022561-rv5j1201	2652	6	and	and	CC
cord-022561-rv5j1201	2652	7	thus	thus	RB
cord-022561-rv5j1201	2652	8	received	receive	VBD
cord-022561-rv5j1201	2652	9	immunosuppressive	immunosuppressive	JJ
cord-022561-rv5j1201	2652	10	drug	drug	NN
cord-022561-rv5j1201	2652	11	therapy	therapy	NN
cord-022561-rv5j1201	2652	12	had	have	VBD
cord-022561-rv5j1201	2652	13	a	a	DT
cord-022561-rv5j1201	2652	14	similar	similar	JJ
cord-022561-rv5j1201	2652	15	risk	risk	NN
cord-022561-rv5j1201	2652	16	for	for	IN
cord-022561-rv5j1201	2652	17	developing	develop	VBG
cord-022561-rv5j1201	2652	18	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2652	19	.	.	.
cord-022561-rv5j1201	2653	1	Both	both	DT
cord-022561-rv5j1201	2653	2	FIVinfected	FIVinfected	NNP
cord-022561-rv5j1201	2653	3	and	and	CC
cord-022561-rv5j1201	2653	4	posttransplantation	posttransplantation	NN
cord-022561-rv5j1201	2653	5	cats	cat	NNS
cord-022561-rv5j1201	2653	6	predominantly	predominantly	RB
cord-022561-rv5j1201	2653	7	developed	develop	VBD
cord-022561-rv5j1201	2653	8	extranodal	extranodal	RB
cord-022561-rv5j1201	2653	9	,	,	,
cord-022561-rv5j1201	2653	10	high	high	JJ
cord-022561-rv5j1201	2653	11	-	-	HYPH
cord-022561-rv5j1201	2653	12	grade	grade	NN
cord-022561-rv5j1201	2653	13	,	,	,
cord-022561-rv5j1201	2653	14	diffuse	diffuse	VBP
cord-022561-rv5j1201	2653	15	large	large	JJ
cord-022561-rv5j1201	2653	16	B	b	NN
cord-022561-rv5j1201	2653	17	lymphocyte	lymphocyte	NN
cord-022561-rv5j1201	2653	18	lymphomas	lymphoma	NNS
cord-022561-rv5j1201	2653	19	.	.	.
cord-022561-rv5j1201	2654	1	This	this	DT
cord-022561-rv5j1201	2654	2	form	form	NN
cord-022561-rv5j1201	2654	3	is	be	VBZ
cord-022561-rv5j1201	2654	4	also	also	RB
cord-022561-rv5j1201	2654	5	the	the	DT
cord-022561-rv5j1201	2654	6	most	most	RBS
cord-022561-rv5j1201	2654	7	common	common	JJ
cord-022561-rv5j1201	2654	8	subtype	subtype	NN
cord-022561-rv5j1201	2654	9	in	in	IN
cord-022561-rv5j1201	2654	10	human	human	JJ
cord-022561-rv5j1201	2654	11	immunodeficiency	immunodeficiency	NN
cord-022561-rv5j1201	2654	12	virus	virus	NN
cord-022561-rv5j1201	2654	13	and	and	CC
cord-022561-rv5j1201	2654	14	posttransplantation	posttransplantation	NN
cord-022561-rv5j1201	2654	15	patients	patient	NNS
cord-022561-rv5j1201	2654	16	caused	cause	VBN
cord-022561-rv5j1201	2654	17	by	by	IN
cord-022561-rv5j1201	2654	18	the	the	DT
cord-022561-rv5j1201	2654	19	Epstein	Epstein	NNP
cord-022561-rv5j1201	2654	20	-	-	HYPH
cord-022561-rv5j1201	2654	21	Barr	Barr	NNP
cord-022561-rv5j1201	2654	22	virus	virus	NN
cord-022561-rv5j1201	2654	23	(	(	-LRB-
cord-022561-rv5j1201	2654	24	EBV	EBV	NNP
cord-022561-rv5j1201	2654	25	)	)	-RRB-
cord-022561-rv5j1201	2654	26	.	.	.
cord-022561-rv5j1201	2655	1	Therefore	therefore	RB
cord-022561-rv5j1201	2655	2	it	-PRON-	PRP
cord-022561-rv5j1201	2655	3	is	be	VBZ
cord-022561-rv5j1201	2655	4	reasonable	reasonable	JJ
cord-022561-rv5j1201	2655	5	to	to	TO
cord-022561-rv5j1201	2655	6	question	question	VB
cord-022561-rv5j1201	2655	7	whether	whether	IN
cord-022561-rv5j1201	2655	8	these	these	DT
cord-022561-rv5j1201	2655	9	two	two	CD
cord-022561-rv5j1201	2655	10	groups	group	NNS
cord-022561-rv5j1201	2655	11	of	of	IN
cord-022561-rv5j1201	2655	12	immunosuppressed	immunosuppressed	JJ
cord-022561-rv5j1201	2655	13	cats	cat	NNS
cord-022561-rv5j1201	2655	14	may	may	MD
cord-022561-rv5j1201	2655	15	be	be	VB
cord-022561-rv5j1201	2655	16	more	more	RBR
cord-022561-rv5j1201	2655	17	prone	prone	JJ
cord-022561-rv5j1201	2655	18	to	to	IN
cord-022561-rv5j1201	2655	19	infection	infection	NN
cord-022561-rv5j1201	2655	20	by	by	IN
cord-022561-rv5j1201	2655	21	a	a	DT
cord-022561-rv5j1201	2655	22	gammaherpesvirus	gammaherpesvirus	NN
cord-022561-rv5j1201	2655	23	similar	similar	JJ
cord-022561-rv5j1201	2655	24	to	to	IN
cord-022561-rv5j1201	2655	25	EBV	EBV	NNP
cord-022561-rv5j1201	2655	26	,	,	,
cord-022561-rv5j1201	2655	27	leading	lead	VBG
cord-022561-rv5j1201	2655	28	to	to	IN
cord-022561-rv5j1201	2655	29	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2655	30	.	.	.
cord-022561-rv5j1201	2656	1	Recently	recently	RB
cord-022561-rv5j1201	2656	2	a	a	DT
cord-022561-rv5j1201	2656	3	novel	novel	JJ
cord-022561-rv5j1201	2656	4	feline	feline	JJ
cord-022561-rv5j1201	2656	5	gammaherpesvirus	gammaherpesvirus	NN
cord-022561-rv5j1201	2656	6	(	(	-LRB-
cord-022561-rv5j1201	2656	7	FcaGHV1	FcaGHV1	NNP
cord-022561-rv5j1201	2656	8	)	)	-RRB-
cord-022561-rv5j1201	2656	9	was	be	VBD
cord-022561-rv5j1201	2656	10	multiple	multiple	JJ
cord-022561-rv5j1201	2656	11	peripheral	peripheral	JJ
cord-022561-rv5j1201	2656	12	lymphadenomegaly	lymphadenomegaly	NNS
cord-022561-rv5j1201	2656	13	(	(	-LRB-
cord-022561-rv5j1201	2656	14	often	often	RB
cord-022561-rv5j1201	2656	15	mandibular	mandibular	JJ
cord-022561-rv5j1201	2656	16	lymph	lymph	NN
cord-022561-rv5j1201	2656	17	nodes	node	NNS
cord-022561-rv5j1201	2656	18	)	)	-RRB-
cord-022561-rv5j1201	2656	19	in	in	IN
cord-022561-rv5j1201	2656	20	otherwise	otherwise	RB
cord-022561-rv5j1201	2656	21	healthy	healthy	RB
cord-022561-rv5j1201	2656	22	-	-	HYPH
cord-022561-rv5j1201	2656	23	appearing	appear	VBG
cord-022561-rv5j1201	2656	24	dogs	dog	NNS
cord-022561-rv5j1201	2656	25	.	.	.
cord-022561-rv5j1201	2657	1	The	the	DT
cord-022561-rv5j1201	2657	2	characteristic	characteristic	JJ
cord-022561-rv5j1201	2657	3	histopathologic	histopathologic	JJ
cord-022561-rv5j1201	2657	4	architecture	architecture	NN
cord-022561-rv5j1201	2657	5	is	be	VBZ
cord-022561-rv5j1201	2657	6	a	a	DT
cord-022561-rv5j1201	2657	7	nodular	nodular	JJ
cord-022561-rv5j1201	2657	8	expansion	expansion	NN
cord-022561-rv5j1201	2657	9	of	of	IN
cord-022561-rv5j1201	2657	10	the	the	DT
cord-022561-rv5j1201	2657	11	paracortex	paracortex	NN
cord-022561-rv5j1201	2657	12	by	by	IN
cord-022561-rv5j1201	2657	13	neoplastic	neoplastic	JJ
cord-022561-rv5j1201	2657	14	cells	cell	NNS
cord-022561-rv5j1201	2657	15	,	,	,
cord-022561-rv5j1201	2657	16	which	which	WDT
cord-022561-rv5j1201	2657	17	push	push	VBP
cord-022561-rv5j1201	2657	18	atrophied	atrophied	JJ
cord-022561-rv5j1201	2657	19	"	"	``
cord-022561-rv5j1201	2657	20	fading	fading	JJ
cord-022561-rv5j1201	2657	21	"	"	''
cord-022561-rv5j1201	2657	22	cortical	cortical	JJ
cord-022561-rv5j1201	2657	23	follicles	follicle	NNS
cord-022561-rv5j1201	2657	24	against	against	IN
cord-022561-rv5j1201	2657	25	the	the	DT
cord-022561-rv5j1201	2657	26	thinned	thin	VBN
cord-022561-rv5j1201	2657	27	capsule	capsule	NN
cord-022561-rv5j1201	2657	28	and	and	CC
cord-022561-rv5j1201	2657	29	trabeculae	trabeculae	NNP
cord-022561-rv5j1201	2657	30	.	.	.
cord-022561-rv5j1201	2658	1	This	this	DT
cord-022561-rv5j1201	2658	2	unique	unique	JJ
cord-022561-rv5j1201	2658	3	architectural	architectural	JJ
cord-022561-rv5j1201	2658	4	feature	feature	NN
cord-022561-rv5j1201	2658	5	is	be	VBZ
cord-022561-rv5j1201	2658	6	best	well	RBS
cord-022561-rv5j1201	2658	7	highlighted	highlight	VBN
cord-022561-rv5j1201	2658	8	with	with	IN
cord-022561-rv5j1201	2658	9	immunohistochemical	immunohistochemical	JJ
cord-022561-rv5j1201	2658	10	stains	stain	NNS
cord-022561-rv5j1201	2658	11	(	(	-LRB-
cord-022561-rv5j1201	2658	12	often	often	RB
cord-022561-rv5j1201	2658	13	CD3	CD3	NNP
cord-022561-rv5j1201	2658	14	for	for	IN
cord-022561-rv5j1201	2658	15	T	T	NNP
cord-022561-rv5j1201	2658	16	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	2658	17	and	and	CC
cord-022561-rv5j1201	2658	18	CD79a	CD79a	NNP
cord-022561-rv5j1201	2658	19	,	,	,
cord-022561-rv5j1201	2658	20	pax5	pax5	NN
cord-022561-rv5j1201	2658	21	,	,	,
cord-022561-rv5j1201	2658	22	or	or	CC
cord-022561-rv5j1201	2658	23	CD20	cd20	NN
cord-022561-rv5j1201	2658	24	for	for	IN
cord-022561-rv5j1201	2658	25	B	b	NN
cord-022561-rv5j1201	2658	26	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	2658	27	)	)	-RRB-
cord-022561-rv5j1201	2658	28	.	.	.
cord-022561-rv5j1201	2659	1	The	the	DT
cord-022561-rv5j1201	2659	2	neoplastic	neoplastic	JJ
cord-022561-rv5j1201	2659	3	cells	cell	NNS
cord-022561-rv5j1201	2659	4	are	be	VBP
cord-022561-rv5j1201	2659	5	small	small	JJ
cord-022561-rv5j1201	2659	6	to	to	TO
cord-022561-rv5j1201	2659	7	intermediate	intermediate	JJ
cord-022561-rv5j1201	2659	8	in	in	IN
cord-022561-rv5j1201	2659	9	size	size	NN
cord-022561-rv5j1201	2659	10	with	with	IN
cord-022561-rv5j1201	2659	11	pale	pale	JJ
cord-022561-rv5j1201	2659	12	eosinophilic	eosinophilic	JJ
cord-022561-rv5j1201	2659	13	cytoplasm	cytoplasm	NN
cord-022561-rv5j1201	2659	14	and	and	CC
cord-022561-rv5j1201	2659	15	oval	oval	JJ
cord-022561-rv5j1201	2659	16	nuclei	nucleus	NNS
cord-022561-rv5j1201	2659	17	with	with	IN
cord-022561-rv5j1201	2659	18	sharp	sharp	JJ
cord-022561-rv5j1201	2659	19	shallow	shallow	JJ
cord-022561-rv5j1201	2659	20	indentations	indentation	NNS
cord-022561-rv5j1201	2659	21	.	.	.
cord-022561-rv5j1201	2660	1	Mitotic	mitotic	JJ
cord-022561-rv5j1201	2660	2	figures	figure	NNS
cord-022561-rv5j1201	2660	3	are	be	VBP
cord-022561-rv5j1201	2660	4	rare	rare	JJ
cord-022561-rv5j1201	2660	5	.	.	.
cord-022561-rv5j1201	2661	1	Dogs	dog	NNS
cord-022561-rv5j1201	2661	2	with	with	IN
cord-022561-rv5j1201	2661	3	this	this	DT
cord-022561-rv5j1201	2661	4	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2661	5	subtype	subtype	NN
cord-022561-rv5j1201	2661	6	tend	tend	VBP
cord-022561-rv5j1201	2661	7	to	to	TO
cord-022561-rv5j1201	2661	8	be	be	VB
cord-022561-rv5j1201	2661	9	diagnosed	diagnose	VBN
cord-022561-rv5j1201	2661	10	with	with	IN
cord-022561-rv5j1201	2661	11	an	an	DT
cord-022561-rv5j1201	2661	12	advanced	advanced	JJ
cord-022561-rv5j1201	2661	13	stage	stage	NN
cord-022561-rv5j1201	2661	14	of	of	IN
cord-022561-rv5j1201	2661	15	the	the	DT
cord-022561-rv5j1201	2661	16	disease	disease	NN
cord-022561-rv5j1201	2661	17	,	,	,
cord-022561-rv5j1201	2661	18	likely	likely	RB
cord-022561-rv5j1201	2661	19	because	because	IN
cord-022561-rv5j1201	2661	20	they	-PRON-	PRP
cord-022561-rv5j1201	2661	21	present	present	VBP
cord-022561-rv5j1201	2661	22	clinically	clinically	RB
cord-022561-rv5j1201	2661	23	healthy	healthy	JJ
cord-022561-rv5j1201	2661	24	,	,	,
cord-022561-rv5j1201	2661	25	without	without	IN
cord-022561-rv5j1201	2661	26	loss	loss	NN
cord-022561-rv5j1201	2661	27	of	of	IN
cord-022561-rv5j1201	2661	28	appetite	appetite	NN
cord-022561-rv5j1201	2661	29	or	or	CC
cord-022561-rv5j1201	2661	30	activity	activity	NN
cord-022561-rv5j1201	2661	31	level	level	NN
cord-022561-rv5j1201	2661	32	.	.	.
cord-022561-rv5j1201	2662	1	Even	even	RB
cord-022561-rv5j1201	2662	2	so	so	RB
cord-022561-rv5j1201	2662	3	,	,	,
cord-022561-rv5j1201	2662	4	dogs	dog	NNS
cord-022561-rv5j1201	2662	5	with	with	IN
cord-022561-rv5j1201	2662	6	T	T	NNP
cord-022561-rv5j1201	2662	7	zone	zone	NN
cord-022561-rv5j1201	2662	8	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2662	9	have	have	VBP
cord-022561-rv5j1201	2662	10	a	a	DT
cord-022561-rv5j1201	2662	11	relatively	relatively	RB
cord-022561-rv5j1201	2662	12	long	long	JJ
cord-022561-rv5j1201	2662	13	survival	survival	NN
cord-022561-rv5j1201	2662	14	time	time	NN
cord-022561-rv5j1201	2662	15	compared	compare	VBN
cord-022561-rv5j1201	2662	16	to	to	IN
cord-022561-rv5j1201	2662	17	other	other	JJ
cord-022561-rv5j1201	2662	18	lymphomas	lymphoma	NNS
cord-022561-rv5j1201	2662	19	:	:	:
cord-022561-rv5j1201	2662	20	reports	report	NNS
cord-022561-rv5j1201	2662	21	on	on	IN
cord-022561-rv5j1201	2662	22	median	median	JJ
cord-022561-rv5j1201	2662	23	survival	survival	NN
cord-022561-rv5j1201	2662	24	time	time	NN
cord-022561-rv5j1201	2662	25	range	range	NN
cord-022561-rv5j1201	2662	26	from	from	IN
cord-022561-rv5j1201	2662	27	13	13	CD
cord-022561-rv5j1201	2662	28	to	to	TO
cord-022561-rv5j1201	2662	29	33	33	CD
cord-022561-rv5j1201	2662	30	months	month	NNS
cord-022561-rv5j1201	2662	31	,	,	,
cord-022561-rv5j1201	2662	32	and	and	CC
cord-022561-rv5j1201	2662	33	data	datum	NNS
cord-022561-rv5j1201	2662	34	suggest	suggest	VBP
cord-022561-rv5j1201	2662	35	that	that	IN
cord-022561-rv5j1201	2662	36	dogs	dog	NNS
cord-022561-rv5j1201	2662	37	who	who	WP
cord-022561-rv5j1201	2662	38	do	do	VBP
cord-022561-rv5j1201	2662	39	not	not	RB
cord-022561-rv5j1201	2662	40	receive	receive	VB
cord-022561-rv5j1201	2662	41	chemotherapy	chemotherapy	NN
cord-022561-rv5j1201	2662	42	actually	actually	RB
cord-022561-rv5j1201	2662	43	have	have	VBP
cord-022561-rv5j1201	2662	44	longer	long	JJR
cord-022561-rv5j1201	2662	45	median	median	JJ
cord-022561-rv5j1201	2662	46	survival	survival	NN
cord-022561-rv5j1201	2662	47	times	time	NNS
cord-022561-rv5j1201	2662	48	.	.	.
cord-022561-rv5j1201	2663	1	Marginal	Marginal	NNP
cord-022561-rv5j1201	2663	2	Zone	Zone	NNP
cord-022561-rv5j1201	2663	3	Lymphoma	Lymphoma	NNP
cord-022561-rv5j1201	2663	4	.	.	.
cord-022561-rv5j1201	2664	1	Marginal	marginal	JJ
cord-022561-rv5j1201	2664	2	zone	zone	NN
cord-022561-rv5j1201	2664	3	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2664	4	is	be	VBZ
cord-022561-rv5j1201	2664	5	an	an	DT
cord-022561-rv5j1201	2664	6	indolent	indolent	JJ
cord-022561-rv5j1201	2664	7	B	b	NN
cord-022561-rv5j1201	2664	8	lymphocyte	lymphocyte	NN
cord-022561-rv5j1201	2664	9	neoplasm	neoplasm	NN
cord-022561-rv5j1201	2664	10	derived	derive	VBN
cord-022561-rv5j1201	2664	11	from	from	IN
cord-022561-rv5j1201	2664	12	the	the	DT
cord-022561-rv5j1201	2664	13	cells	cell	NNS
cord-022561-rv5j1201	2664	14	of	of	IN
cord-022561-rv5j1201	2664	15	the	the	DT
cord-022561-rv5j1201	2664	16	marginal	marginal	JJ
cord-022561-rv5j1201	2664	17	zone	zone	NN
cord-022561-rv5j1201	2664	18	of	of	IN
cord-022561-rv5j1201	2664	19	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	2664	20	follicles	follicle	NNS
cord-022561-rv5j1201	2664	21	.	.	.
cord-022561-rv5j1201	2665	1	Most	Most	JJS
cord-022561-rv5j1201	2665	2	marginal	marginal	JJ
cord-022561-rv5j1201	2665	3	zone	zone	NN
cord-022561-rv5j1201	2665	4	lymphomas	lymphoma	NNS
cord-022561-rv5j1201	2665	5	(	(	-LRB-
cord-022561-rv5j1201	2665	6	and	and	CC
cord-022561-rv5j1201	2665	7	mantle	mantle	NN
cord-022561-rv5j1201	2665	8	cell	cell	NN
cord-022561-rv5j1201	2665	9	lymphomas	lymphoma	NNS
cord-022561-rv5j1201	2665	10	)	)	-RRB-
cord-022561-rv5j1201	2665	11	are	be	VBP
cord-022561-rv5j1201	2665	12	assumed	assume	VBN
cord-022561-rv5j1201	2665	13	to	to	TO
cord-022561-rv5j1201	2665	14	originate	originate	VB
cord-022561-rv5j1201	2665	15	in	in	IN
cord-022561-rv5j1201	2665	16	the	the	DT
cord-022561-rv5j1201	2665	17	spleen	spleen	NN
cord-022561-rv5j1201	2665	18	with	with	IN
cord-022561-rv5j1201	2665	19	slow	slow	JJ
cord-022561-rv5j1201	2665	20	spread	spread	NN
cord-022561-rv5j1201	2665	21	to	to	IN
cord-022561-rv5j1201	2665	22	lymph	lymph	NN
cord-022561-rv5j1201	2665	23	nodes	node	NNS
cord-022561-rv5j1201	2665	24	and	and	CC
cord-022561-rv5j1201	2665	25	often	often	RB
cord-022561-rv5j1201	2665	26	present	present	JJ
cord-022561-rv5j1201	2665	27	as	as	IN
cord-022561-rv5j1201	2665	28	a	a	DT
cord-022561-rv5j1201	2665	29	mottled	mottled	JJ
cord-022561-rv5j1201	2665	30	white	white	JJ
cord-022561-rv5j1201	2665	31	-	-	HYPH
cord-022561-rv5j1201	2665	32	red	red	JJ
cord-022561-rv5j1201	2665	33	smooth	smooth	JJ
cord-022561-rv5j1201	2665	34	spherical	spherical	JJ
cord-022561-rv5j1201	2665	35	splenic	splenic	JJ
cord-022561-rv5j1201	2665	36	mass	mass	NN
cord-022561-rv5j1201	2665	37	.	.	.
cord-022561-rv5j1201	2666	1	Histopathologic	Histopathologic	NNP
cord-022561-rv5j1201	2666	2	assessment	assessment	NN
cord-022561-rv5j1201	2666	3	of	of	IN
cord-022561-rv5j1201	2666	4	tissue	tissue	NN
cord-022561-rv5j1201	2666	5	architecture	architecture	NN
cord-022561-rv5j1201	2666	6	is	be	VBZ
cord-022561-rv5j1201	2666	7	needed	need	VBN
cord-022561-rv5j1201	2666	8	for	for	IN
cord-022561-rv5j1201	2666	9	a	a	DT
cord-022561-rv5j1201	2666	10	diagnosis	diagnosis	NN
cord-022561-rv5j1201	2666	11	of	of	IN
cord-022561-rv5j1201	2666	12	marginal	marginal	JJ
cord-022561-rv5j1201	2666	13	zone	zone	NN
cord-022561-rv5j1201	2666	14	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2666	15	and	and	CC
cord-022561-rv5j1201	2666	16	is	be	VBZ
cord-022561-rv5j1201	2666	17	characterized	characterize	VBN
cord-022561-rv5j1201	2666	18	by	by	IN
cord-022561-rv5j1201	2666	19	a	a	DT
cord-022561-rv5j1201	2666	20	distinct	distinct	JJ
cord-022561-rv5j1201	2666	21	nodular	nodular	JJ
cord-022561-rv5j1201	2666	22	pattern	pattern	NN
cord-022561-rv5j1201	2666	23	in	in	IN
cord-022561-rv5j1201	2666	24	which	which	WDT
cord-022561-rv5j1201	2666	25	the	the	DT
cord-022561-rv5j1201	2666	26	lighter	light	JJR
cord-022561-rv5j1201	2666	27	-	-	HYPH
cord-022561-rv5j1201	2666	28	staining	stain	VBG
cord-022561-rv5j1201	2666	29	neoplastic	neoplastic	JJ
cord-022561-rv5j1201	2666	30	marginal	marginal	JJ
cord-022561-rv5j1201	2666	31	zone	zone	NN
cord-022561-rv5j1201	2666	32	cells	cell	NNS
cord-022561-rv5j1201	2666	33	form	form	VBP
cord-022561-rv5j1201	2666	34	a	a	DT
cord-022561-rv5j1201	2666	35	dense	dense	JJ
cord-022561-rv5j1201	2666	36	cuff	cuff	NN
cord-022561-rv5j1201	2666	37	around	around	IN
cord-022561-rv5j1201	2666	38	small	small	JJ
cord-022561-rv5j1201	2666	39	foci	focus	NNS
cord-022561-rv5j1201	2666	40	of	of	IN
cord-022561-rv5j1201	2666	41	darkly	darkly	RB
cord-022561-rv5j1201	2666	42	stained	stain	VBN
cord-022561-rv5j1201	2666	43	mantle	mantle	NN
cord-022561-rv5j1201	2666	44	cells	cell	NNS
cord-022561-rv5j1201	2666	45	(	(	-LRB-
cord-022561-rv5j1201	2666	46	fading	fade	VBG
cord-022561-rv5j1201	2666	47	follicles	follicle	NNS
cord-022561-rv5j1201	2666	48	)	)	-RRB-
cord-022561-rv5j1201	2666	49	.	.	.
cord-022561-rv5j1201	2667	1	The	the	DT
cord-022561-rv5j1201	2667	2	neoplastic	neoplastic	JJ
cord-022561-rv5j1201	2667	3	marginal	marginal	JJ
cord-022561-rv5j1201	2667	4	zone	zone	NN
cord-022561-rv5j1201	2667	5	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	2667	6	are	be	VBP
cord-022561-rv5j1201	2667	7	intermediate	intermediate	JJ
cord-022561-rv5j1201	2667	8	in	in	IN
cord-022561-rv5j1201	2667	9	size	size	NN
cord-022561-rv5j1201	2667	10	and	and	CC
cord-022561-rv5j1201	2667	11	have	have	VBP
cord-022561-rv5j1201	2667	12	a	a	DT
cord-022561-rv5j1201	2667	13	single	single	JJ
cord-022561-rv5j1201	2667	14	prominent	prominent	JJ
cord-022561-rv5j1201	2667	15	central	central	JJ
cord-022561-rv5j1201	2667	16	nucleolus	nucleolus	NN
cord-022561-rv5j1201	2667	17	.	.	.
cord-022561-rv5j1201	2668	1	Mitotic	mitotic	JJ
cord-022561-rv5j1201	2668	2	figures	figure	NNS
cord-022561-rv5j1201	2668	3	are	be	VBP
cord-022561-rv5j1201	2668	4	often	often	RB
cord-022561-rv5j1201	2668	5	rare	rare	JJ
cord-022561-rv5j1201	2668	6	or	or	CC
cord-022561-rv5j1201	2668	7	absent	absent	JJ
cord-022561-rv5j1201	2668	8	early	early	RB
cord-022561-rv5j1201	2668	9	on	on	RB
cord-022561-rv5j1201	2668	10	and	and	CC
cord-022561-rv5j1201	2668	11	increase	increase	VB
cord-022561-rv5j1201	2668	12	with	with	IN
cord-022561-rv5j1201	2668	13	disease	disease	NN
cord-022561-rv5j1201	2668	14	progression	progression	NN
cord-022561-rv5j1201	2668	15	.	.	.
cord-022561-rv5j1201	2669	1	Differentiating	differentiate	VBG
cord-022561-rv5j1201	2669	2	between	between	IN
cord-022561-rv5j1201	2669	3	marginal	marginal	JJ
cord-022561-rv5j1201	2669	4	zone	zone	NN
cord-022561-rv5j1201	2669	5	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2669	6	and	and	CC
cord-022561-rv5j1201	2669	7	marginal	marginal	JJ
cord-022561-rv5j1201	2669	8	zone	zone	NN
cord-022561-rv5j1201	2669	9	hyperplasia	hyperplasia	NN
cord-022561-rv5j1201	2669	10	(	(	-LRB-
cord-022561-rv5j1201	2669	11	which	which	WDT
cord-022561-rv5j1201	2669	12	refers	refer	VBZ
cord-022561-rv5j1201	2669	13	to	to	IN
cord-022561-rv5j1201	2669	14	a	a	DT
cord-022561-rv5j1201	2669	15	proliferation	proliferation	NN
cord-022561-rv5j1201	2669	16	of	of	IN
cord-022561-rv5j1201	2669	17	marginal	marginal	JJ
cord-022561-rv5j1201	2669	18	zone	zone	NN
cord-022561-rv5j1201	2669	19	cells	cell	NNS
cord-022561-rv5j1201	2669	20	and	and	CC
cord-022561-rv5j1201	2669	21	contains	contain	VBZ
cord-022561-rv5j1201	2669	22	a	a	DT
cord-022561-rv5j1201	2669	23	mixture	mixture	NN
cord-022561-rv5j1201	2669	24	of	of	IN
cord-022561-rv5j1201	2669	25	small	small	JJ
cord-022561-rv5j1201	2669	26	and	and	CC
cord-022561-rv5j1201	2669	27	intermediate	intermediate	JJ
cord-022561-rv5j1201	2669	28	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	2669	29	)	)	-RRB-
cord-022561-rv5j1201	2669	30	is	be	VBZ
cord-022561-rv5j1201	2669	31	challenging	challenging	JJ
cord-022561-rv5j1201	2669	32	because	because	IN
cord-022561-rv5j1201	2669	33	marginal	marginal	JJ
cord-022561-rv5j1201	2669	34	zone	zone	NN
cord-022561-rv5j1201	2669	35	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2669	36	arises	arise	VBZ
cord-022561-rv5j1201	2669	37	on	on	IN
cord-022561-rv5j1201	2669	38	the	the	DT
cord-022561-rv5j1201	2669	39	background	background	NN
cord-022561-rv5j1201	2669	40	of	of	IN
cord-022561-rv5j1201	2669	41	marginal	marginal	JJ
cord-022561-rv5j1201	2669	42	zone	zone	NN
cord-022561-rv5j1201	2669	43	hyperplasia	hyperplasia	NN
cord-022561-rv5j1201	2669	44	.	.	.
cord-022561-rv5j1201	2670	1	Additionally	additionally	RB
cord-022561-rv5j1201	2670	2	,	,	,
cord-022561-rv5j1201	2670	3	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	2670	4	and	and	CC
cord-022561-rv5j1201	2670	5	complex	complex	JJ
cord-022561-rv5j1201	2670	6	nodular	nodular	JJ
cord-022561-rv5j1201	2670	7	hyperplasia	hyperplasia	NN
cord-022561-rv5j1201	2670	8	are	be	VBP
cord-022561-rv5j1201	2670	9	common	common	JJ
cord-022561-rv5j1201	2670	10	in	in	IN
cord-022561-rv5j1201	2670	11	the	the	DT
cord-022561-rv5j1201	2670	12	dog	dog	NN
cord-022561-rv5j1201	2670	13	spleen	spleen	NNS
cord-022561-rv5j1201	2670	14	(	(	-LRB-
cord-022561-rv5j1201	2670	15	see	see	VB
cord-022561-rv5j1201	2670	16	Disorders	disorder	NNS
cord-022561-rv5j1201	2670	17	of	of	IN
cord-022561-rv5j1201	2670	18	Dogs	Dogs	NNP
cord-022561-rv5j1201	2670	19	)	)	-RRB-
cord-022561-rv5j1201	2670	20	,	,	,
cord-022561-rv5j1201	2670	21	and	and	CC
cord-022561-rv5j1201	2670	22	it	-PRON-	PRP
cord-022561-rv5j1201	2670	23	is	be	VBZ
cord-022561-rv5j1201	2670	24	possible	possible	JJ
cord-022561-rv5j1201	2670	25	that	that	IN
cord-022561-rv5j1201	2670	26	many	many	JJ
cord-022561-rv5j1201	2670	27	cases	case	NNS
cord-022561-rv5j1201	2670	28	of	of	IN
cord-022561-rv5j1201	2670	29	nodular	nodular	JJ
cord-022561-rv5j1201	2670	30	hyperplasia	hyperplasia	NN
cord-022561-rv5j1201	2670	31	contain	contain	VBP
cord-022561-rv5j1201	2670	32	areas	area	NNS
cord-022561-rv5j1201	2670	33	of	of	IN
cord-022561-rv5j1201	2670	34	marginal	marginal	JJ
cord-022561-rv5j1201	2670	35	zone	zone	NN
cord-022561-rv5j1201	2670	36	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2670	37	.	.	.
cord-022561-rv5j1201	2671	1	Therefore	therefore	RB
cord-022561-rv5j1201	2671	2	immunophenotyping	immunophenotyping	NN
cord-022561-rv5j1201	2671	3	and	and	CC
cord-022561-rv5j1201	2671	4	molecular	molecular	JJ
cord-022561-rv5j1201	2671	5	clonality	clonality	NN
cord-022561-rv5j1201	2671	6	are	be	VBP
cord-022561-rv5j1201	2671	7	ultimately	ultimately	RB
cord-022561-rv5j1201	2671	8	required	require	VBN
cord-022561-rv5j1201	2671	9	for	for	IN
cord-022561-rv5j1201	2671	10	a	a	DT
cord-022561-rv5j1201	2671	11	definitive	definitive	JJ
cord-022561-rv5j1201	2671	12	diagnosis	diagnosis	NN
cord-022561-rv5j1201	2671	13	of	of	IN
cord-022561-rv5j1201	2671	14	marginal	marginal	JJ
cord-022561-rv5j1201	2671	15	zone	zone	NN
cord-022561-rv5j1201	2671	16	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2671	17	.	.	.
cord-022561-rv5j1201	2672	1	The	the	DT
cord-022561-rv5j1201	2672	2	overall	overall	JJ
cord-022561-rv5j1201	2672	3	median	median	JJ
cord-022561-rv5j1201	2672	4	survival	survival	NN
cord-022561-rv5j1201	2672	5	time	time	NN
cord-022561-rv5j1201	2672	6	in	in	IN
cord-022561-rv5j1201	2672	7	dogs	dog	NNS
cord-022561-rv5j1201	2672	8	with	with	IN
cord-022561-rv5j1201	2672	9	splenic	splenic	JJ
cord-022561-rv5j1201	2672	10	marginal	marginal	JJ
cord-022561-rv5j1201	2672	11	zone	zone	NN
cord-022561-rv5j1201	2672	12	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2672	13	after	after	IN
cord-022561-rv5j1201	2672	14	splenectomy	splenectomy	NN
cord-022561-rv5j1201	2672	15	is	be	VBZ
cord-022561-rv5j1201	2672	16	approximately	approximately	RB
cord-022561-rv5j1201	2672	17	13	13	CD
cord-022561-rv5j1201	2672	18	months	month	NNS
cord-022561-rv5j1201	2672	19	(	(	-LRB-
cord-022561-rv5j1201	2672	20	even	even	RB
cord-022561-rv5j1201	2672	21	longer	long	RBR
cord-022561-rv5j1201	2672	22	if	if	IN
cord-022561-rv5j1201	2672	23	it	-PRON-	PRP
cord-022561-rv5j1201	2672	24	is	be	VBZ
cord-022561-rv5j1201	2672	25	diagnosed	diagnose	VBN
cord-022561-rv5j1201	2672	26	as	as	IN
cord-022561-rv5j1201	2672	27	an	an	DT
cord-022561-rv5j1201	2672	28	incidental	incidental	JJ
cord-022561-rv5j1201	2672	29	finding	finding	NN
cord-022561-rv5j1201	2672	30	)	)	-RRB-
cord-022561-rv5j1201	2672	31	.	.	.
cord-022561-rv5j1201	2673	1	Plasmacytomas	Plasmacytomas	NNP
cord-022561-rv5j1201	2673	2	.	.	.
cord-022561-rv5j1201	2674	1	See	see	VB
cord-022561-rv5j1201	2674	2	Disorders	disorder	NNS
cord-022561-rv5j1201	2674	3	of	of	IN
cord-022561-rv5j1201	2674	4	Domestic	domestic	JJ
cord-022561-rv5j1201	2674	5	Animals	animal	NNS
cord-022561-rv5j1201	2674	6	:	:	:
cord-022561-rv5j1201	2674	7	Lymph	lymph	NN
cord-022561-rv5j1201	2674	8	Nodes	node	NNS
cord-022561-rv5j1201	2674	9	,	,	,
cord-022561-rv5j1201	2674	10	Neoplasia	Neoplasia	NNP
cord-022561-rv5j1201	2674	11	,	,	,
cord-022561-rv5j1201	2674	12	Plasma	plasma	NN
cord-022561-rv5j1201	2674	13	Cell	Cell	NNP
cord-022561-rv5j1201	2674	14	Neoplasia	Neoplasia	NNP
cord-022561-rv5j1201	2674	15	,	,	,
cord-022561-rv5j1201	2674	16	Extramedullary	Extramedullary	NNP
cord-022561-rv5j1201	2674	17	Plasmacytomas	Plasmacytomas	NNP
cord-022561-rv5j1201	2674	18	(	(	-LRB-
cord-022561-rv5j1201	2674	19	see	see	VB
cord-022561-rv5j1201	2674	20	Fig	Fig	NNP
cord-022561-rv5j1201	2674	21	.	.	.
cord-022561-rv5j1201	2674	22	13	13	CD
cord-022561-rv5j1201	2674	23	-84	-84	NNS
cord-022561-rv5j1201	2674	24	)	)	-RRB-
cord-022561-rv5j1201	2674	25	.	.	.
cord-022561-rv5j1201	2675	1	Feline	feline	JJ
cord-022561-rv5j1201	2675	2	panleukopenia	panleukopenia	NN
cord-022561-rv5j1201	2675	3	,	,	,
cord-022561-rv5j1201	2675	4	caused	cause	VBN
cord-022561-rv5j1201	2675	5	by	by	IN
cord-022561-rv5j1201	2675	6	the	the	DT
cord-022561-rv5j1201	2675	7	single	single	RB
cord-022561-rv5j1201	2675	8	-	-	HYPH
cord-022561-rv5j1201	2675	9	stranded	strand	VBN
cord-022561-rv5j1201	2675	10	DNA	dna	NN
cord-022561-rv5j1201	2675	11	virus	virus	NN
cord-022561-rv5j1201	2675	12	feline	feline	JJ
cord-022561-rv5j1201	2675	13	parvovirus	parvovirus	NN
cord-022561-rv5j1201	2675	14	(	(	-LRB-
cord-022561-rv5j1201	2675	15	FPV	FPV	NNP
cord-022561-rv5j1201	2675	16	)	)	-RRB-
cord-022561-rv5j1201	2675	17	,	,	,
cord-022561-rv5j1201	2675	18	is	be	VBZ
cord-022561-rv5j1201	2675	19	a	a	DT
cord-022561-rv5j1201	2675	20	highly	highly	RB
cord-022561-rv5j1201	2675	21	contagious	contagious	JJ
cord-022561-rv5j1201	2675	22	and	and	CC
cord-022561-rv5j1201	2675	23	often	often	RB
cord-022561-rv5j1201	2675	24	lethal	lethal	JJ
cord-022561-rv5j1201	2675	25	disease	disease	NN
cord-022561-rv5j1201	2675	26	of	of	IN
cord-022561-rv5j1201	2675	27	cats	cat	NNS
cord-022561-rv5j1201	2675	28	and	and	CC
cord-022561-rv5j1201	2675	29	other	other	JJ
cord-022561-rv5j1201	2675	30	Felidae	Felidae	NNP
cord-022561-rv5j1201	2675	31	,	,	,
cord-022561-rv5j1201	2675	32	as	as	RB
cord-022561-rv5j1201	2675	33	well	well	RB
cord-022561-rv5j1201	2675	34	as	as	IN
cord-022561-rv5j1201	2675	35	other	other	JJ
cord-022561-rv5j1201	2675	36	species	specie	NNS
cord-022561-rv5j1201	2675	37	(	(	-LRB-
cord-022561-rv5j1201	2675	38	including	include	VBG
cord-022561-rv5j1201	2675	39	raccoons	raccoon	NNS
cord-022561-rv5j1201	2675	40	,	,	,
cord-022561-rv5j1201	2675	41	ring	ring	NN
cord-022561-rv5j1201	2675	42	-	-	HYPH
cord-022561-rv5j1201	2675	43	tailed	tailed	JJ
cord-022561-rv5j1201	2675	44	cats	cat	NNS
cord-022561-rv5j1201	2675	45	,	,	,
cord-022561-rv5j1201	2675	46	foxes	fox	NNS
cord-022561-rv5j1201	2675	47	,	,	,
cord-022561-rv5j1201	2675	48	and	and	CC
cord-022561-rv5j1201	2675	49	minks	mink	NNS
cord-022561-rv5j1201	2675	50	)	)	-RRB-
cord-022561-rv5j1201	2675	51	.	.	.
cord-022561-rv5j1201	2676	1	FPV	FPV	NNP
cord-022561-rv5j1201	2676	2	is	be	VBZ
cord-022561-rv5j1201	2676	3	transmitted	transmit	VBN
cord-022561-rv5j1201	2676	4	by	by	IN
cord-022561-rv5j1201	2676	5	the	the	DT
cord-022561-rv5j1201	2676	6	fecal	fecal	JJ
cord-022561-rv5j1201	2676	7	-	-	HYPH
cord-022561-rv5j1201	2676	8	oral	oral	JJ
cord-022561-rv5j1201	2676	9	route	route	NN
cord-022561-rv5j1201	2676	10	through	through	IN
cord-022561-rv5j1201	2676	11	contact	contact	NN
cord-022561-rv5j1201	2676	12	with	with	IN
cord-022561-rv5j1201	2676	13	infected	infected	JJ
cord-022561-rv5j1201	2676	14	body	body	NN
cord-022561-rv5j1201	2676	15	fluids	fluid	NNS
cord-022561-rv5j1201	2676	16	,	,	,
cord-022561-rv5j1201	2676	17	feces	fece	NNS
cord-022561-rv5j1201	2676	18	,	,	,
cord-022561-rv5j1201	2676	19	or	or	CC
cord-022561-rv5j1201	2676	20	fomites	fomite	NNS
cord-022561-rv5j1201	2676	21	.	.	.
cord-022561-rv5j1201	2677	1	Following	follow	VBG
cord-022561-rv5j1201	2677	2	intranasal	intranasal	JJ
cord-022561-rv5j1201	2677	3	or	or	CC
cord-022561-rv5j1201	2677	4	oral	oral	JJ
cord-022561-rv5j1201	2677	5	infection	infection	NN
cord-022561-rv5j1201	2677	6	,	,	,
cord-022561-rv5j1201	2677	7	the	the	DT
cord-022561-rv5j1201	2677	8	virus	virus	NN
cord-022561-rv5j1201	2677	9	initially	initially	RB
cord-022561-rv5j1201	2677	10	replicates	replicate	VBZ
cord-022561-rv5j1201	2677	11	in	in	IN
cord-022561-rv5j1201	2677	12	the	the	DT
cord-022561-rv5j1201	2677	13	macrophages	macrophage	NNS
cord-022561-rv5j1201	2677	14	in	in	IN
cord-022561-rv5j1201	2677	15	the	the	DT
cord-022561-rv5j1201	2677	16	lamina	lamina	JJ
cord-022561-rv5j1201	2677	17	propria	propria	NN
cord-022561-rv5j1201	2677	18	of	of	IN
cord-022561-rv5j1201	2677	19	the	the	DT
cord-022561-rv5j1201	2677	20	oropharynx	oropharynx	NN
cord-022561-rv5j1201	2677	21	and	and	CC
cord-022561-rv5j1201	2677	22	regional	regional	JJ
cord-022561-rv5j1201	2677	23	lymph	lymph	NN
cord-022561-rv5j1201	2677	24	nodes	node	NNS
cord-022561-rv5j1201	2677	25	,	,	,
cord-022561-rv5j1201	2677	26	followed	follow	VBN
cord-022561-rv5j1201	2677	27	by	by	IN
cord-022561-rv5j1201	2677	28	viremia	viremia	NNP
cord-022561-rv5j1201	2677	29	,	,	,
cord-022561-rv5j1201	2677	30	which	which	WDT
cord-022561-rv5j1201	2677	31	distributes	distribute	VBZ
cord-022561-rv5j1201	2677	32	the	the	DT
cord-022561-rv5j1201	2677	33	virus	virus	NN
cord-022561-rv5j1201	2677	34	throughout	throughout	IN
cord-022561-rv5j1201	2677	35	the	the	DT
cord-022561-rv5j1201	2677	36	body	body	NN
cord-022561-rv5j1201	2677	37	.	.	.
cord-022561-rv5j1201	2678	1	Because	because	IN
cord-022561-rv5j1201	2678	2	FPV	FPV	NNP
cord-022561-rv5j1201	2678	3	requires	require	VBZ
cord-022561-rv5j1201	2678	4	rapidly	rapidly	RB
cord-022561-rv5j1201	2678	5	multiplying	multiply	VBG
cord-022561-rv5j1201	2678	6	cells	cell	NNS
cord-022561-rv5j1201	2678	7	in	in	IN
cord-022561-rv5j1201	2678	8	the	the	DT
cord-022561-rv5j1201	2678	9	S	S	NNP
cord-022561-rv5j1201	2678	10	phase	phase	NN
cord-022561-rv5j1201	2678	11	of	of	IN
cord-022561-rv5j1201	2678	12	division	division	NN
cord-022561-rv5j1201	2678	13	for	for	IN
cord-022561-rv5j1201	2678	14	its	-PRON-	PRP$
cord-022561-rv5j1201	2678	15	replication	replication	NN
cord-022561-rv5j1201	2678	16	,	,	,
cord-022561-rv5j1201	2678	17	replication	replication	NN
cord-022561-rv5j1201	2678	18	occurs	occur	VBZ
cord-022561-rv5j1201	2678	19	in	in	IN
cord-022561-rv5j1201	2678	20	mitotically	mitotically	RB
cord-022561-rv5j1201	2678	21	active	active	JJ
cord-022561-rv5j1201	2678	22	tissues	tissue	NNS
cord-022561-rv5j1201	2678	23	(	(	-LRB-
cord-022561-rv5j1201	2678	24	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	2678	25	tissue	tissue	NN
cord-022561-rv5j1201	2678	26	,	,	,
cord-022561-rv5j1201	2678	27	bone	bone	NN
cord-022561-rv5j1201	2678	28	marrow	marrow	NN
cord-022561-rv5j1201	2678	29	,	,	,
cord-022561-rv5j1201	2678	30	and	and	CC
cord-022561-rv5j1201	2678	31	intestinal	intestinal	JJ
cord-022561-rv5j1201	2678	32	mucosa	mucosa	NN
cord-022561-rv5j1201	2678	33	)	)	-RRB-
cord-022561-rv5j1201	2678	34	.	.	.
cord-022561-rv5j1201	2679	1	By	by	IN
cord-022561-rv5j1201	2679	2	infecting	infect	VBG
cord-022561-rv5j1201	2679	3	lymphoid	lymphoid	JJ
cord-022561-rv5j1201	2679	4	tissues	tissue	NNS
cord-022561-rv5j1201	2679	5	,	,	,
cord-022561-rv5j1201	2679	6	FPV	FPV	NNP
cord-022561-rv5j1201	2679	7	causes	cause	VBZ
cord-022561-rv5j1201	2679	8	immunosuppression	immunosuppression	NN
cord-022561-rv5j1201	2679	9	directly	directly	RB
cord-022561-rv5j1201	2679	10	through	through	IN
cord-022561-rv5j1201	2679	11	lymphocytolysis	lymphocytolysis	NNP
cord-022561-rv5j1201	2679	12	and	and	CC
cord-022561-rv5j1201	2679	13	of	of	IN
cord-022561-rv5j1201	2679	14	the	the	DT
cord-022561-rv5j1201	2679	15	small	small	JJ
cord-022561-rv5j1201	2679	16	intestine	intestine	NN
cord-022561-rv5j1201	2679	17	.	.	.
cord-022561-rv5j1201	2680	1	The	the	DT
cord-022561-rv5j1201	2680	2	neoplastic	neoplastic	JJ
cord-022561-rv5j1201	2680	3	cells	cell	NNS
cord-022561-rv5j1201	2680	4	are	be	VBP
cord-022561-rv5j1201	2680	5	small	small	JJ
cord-022561-rv5j1201	2680	6	(	(	-LRB-
cord-022561-rv5j1201	2680	7	nuclei	nucleus	NNS
cord-022561-rv5j1201	2680	8	are	be	VBP
cord-022561-rv5j1201	2680	9	equal	equal	JJ
cord-022561-rv5j1201	2680	10	to	to	IN
cord-022561-rv5j1201	2680	11	the	the	DT
cord-022561-rv5j1201	2680	12	diameter	diameter	NN
cord-022561-rv5j1201	2680	13	of	of	IN
cord-022561-rv5j1201	2680	14	a	a	DT
cord-022561-rv5j1201	2680	15	feline	feline	JJ
cord-022561-rv5j1201	2680	16	RBC	RBC	NNP
cord-022561-rv5j1201	2680	17	)	)	-RRB-
cord-022561-rv5j1201	2680	18	,	,	,
cord-022561-rv5j1201	2680	19	mitotic	mitotic	JJ
cord-022561-rv5j1201	2680	20	figures	figure	NNS
cord-022561-rv5j1201	2680	21	are	be	VBP
cord-022561-rv5j1201	2680	22	infrequent	infrequent	JJ
cord-022561-rv5j1201	2680	23	(	(	-LRB-
cord-022561-rv5j1201	2680	24	low	low	JJ
cord-022561-rv5j1201	2680	25	grade	grade	NN
cord-022561-rv5j1201	2680	26	)	)	-RRB-
cord-022561-rv5j1201	2680	27	,	,	,
cord-022561-rv5j1201	2680	28	and	and	CC
cord-022561-rv5j1201	2680	29	mucosal	mucosal	JJ
cord-022561-rv5j1201	2680	30	and	and	CC
cord-022561-rv5j1201	2680	31	crypt	crypt	JJ
cord-022561-rv5j1201	2680	32	epitheliotropism	epitheliotropism	NN
cord-022561-rv5j1201	2680	33	is	be	VBZ
cord-022561-rv5j1201	2680	34	common	common	JJ
cord-022561-rv5j1201	2680	35	(	(	-LRB-
cord-022561-rv5j1201	2680	36	see	see	VB
cord-022561-rv5j1201	2680	37	Fig	Fig	NNP
cord-022561-rv5j1201	2680	38	.	.	.
cord-022561-rv5j1201	2681	1	13	13	CD
cord-022561-rv5j1201	2681	2	-	-	SYM
cord-022561-rv5j1201	2681	3	95	95	CD
cord-022561-rv5j1201	2681	4	)	)	-RRB-
cord-022561-rv5j1201	2681	5	.	.	.
cord-022561-rv5j1201	2682	1	A	a	DT
cord-022561-rv5j1201	2682	2	diagnosis	diagnosis	NN
cord-022561-rv5j1201	2682	3	of	of	IN
cord-022561-rv5j1201	2682	4	this	this	DT
cord-022561-rv5j1201	2682	5	subtype	subtype	NN
cord-022561-rv5j1201	2682	6	of	of	IN
cord-022561-rv5j1201	2682	7	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2682	8	may	may	MD
cord-022561-rv5j1201	2682	9	be	be	VB
cord-022561-rv5j1201	2682	10	difficult	difficult	JJ
cord-022561-rv5j1201	2682	11	(	(	-LRB-
cord-022561-rv5j1201	2682	12	particularly	particularly	RB
cord-022561-rv5j1201	2682	13	in	in	IN
cord-022561-rv5j1201	2682	14	endoscopic	endoscopic	JJ
cord-022561-rv5j1201	2682	15	biopsy	biopsy	NN
cord-022561-rv5j1201	2682	16	samples	sample	NNS
cord-022561-rv5j1201	2682	17	)	)	-RRB-
cord-022561-rv5j1201	2682	18	,	,	,
cord-022561-rv5j1201	2682	19	because	because	IN
cord-022561-rv5j1201	2682	20	this	this	DT
cord-022561-rv5j1201	2682	21	disease	disease	NN
cord-022561-rv5j1201	2682	22	often	often	RB
cord-022561-rv5j1201	2682	23	is	be	VBZ
cord-022561-rv5j1201	2682	24	multifocal	multifocal	JJ
cord-022561-rv5j1201	2682	25	and	and	CC
cord-022561-rv5j1201	2682	26	concurrent	concurrent	JJ
cord-022561-rv5j1201	2682	27	with	with	IN
cord-022561-rv5j1201	2682	28	or	or	CC
cord-022561-rv5j1201	2682	29	arises	arise	VBZ
cord-022561-rv5j1201	2682	30	within	within	IN
cord-022561-rv5j1201	2682	31	lymphoplasmacytic	lymphoplasmacytic	JJ
cord-022561-rv5j1201	2682	32	inflammatory	inflammatory	JJ
cord-022561-rv5j1201	2682	33	bowel	bowel	NN
cord-022561-rv5j1201	2682	34	disease	disease	NN
cord-022561-rv5j1201	2682	35	(	(	-LRB-
cord-022561-rv5j1201	2682	36	IBD	IBD	NNP
cord-022561-rv5j1201	2682	37	)	)	-RRB-
cord-022561-rv5j1201	2682	38	.	.	.
cord-022561-rv5j1201	2683	1	The	the	DT
cord-022561-rv5j1201	2683	2	neoplastic	neoplastic	JJ
cord-022561-rv5j1201	2683	3	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	2683	4	are	be	VBP
cord-022561-rv5j1201	2683	5	morphologically	morphologically	RB
cord-022561-rv5j1201	2683	6	similar	similar	JJ
cord-022561-rv5j1201	2683	7	to	to	IN
cord-022561-rv5j1201	2683	8	the	the	DT
cord-022561-rv5j1201	2683	9	inflammatory	inflammatory	JJ
cord-022561-rv5j1201	2683	10	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	2683	11	.	.	.
cord-022561-rv5j1201	2684	1	Early	early	JJ
cord-022561-rv5j1201	2684	2	small	small	JJ
cord-022561-rv5j1201	2684	3	cell	cell	NN
cord-022561-rv5j1201	2684	4	mucosal	mucosal	NN
cord-022561-rv5j1201	2684	5	T	t	NN
cord-022561-rv5j1201	2684	6	cell	cell	NN
cord-022561-rv5j1201	2684	7	lymphomas	lymphoma	NNS
cord-022561-rv5j1201	2684	8	often	often	RB
cord-022561-rv5j1201	2684	9	require	require	VBP
cord-022561-rv5j1201	2684	10	additional	additional	JJ
cord-022561-rv5j1201	2684	11	diagnostic	diagnostic	JJ
cord-022561-rv5j1201	2684	12	testing	testing	NN
cord-022561-rv5j1201	2684	13	,	,	,
cord-022561-rv5j1201	2684	14	namely	namely	RB
cord-022561-rv5j1201	2684	15	,	,	,
cord-022561-rv5j1201	2684	16	immunohistochemistry	immunohistochemistry	NN
cord-022561-rv5j1201	2684	17	and	and	CC
cord-022561-rv5j1201	2684	18	molecular	molecular	JJ
cord-022561-rv5j1201	2684	19	clonality	clonality	NN
cord-022561-rv5j1201	2684	20	testing	testing	NN
cord-022561-rv5j1201	2684	21	(	(	-LRB-
cord-022561-rv5j1201	2684	22	PCR	PCR	NNP
cord-022561-rv5j1201	2684	23	for	for	IN
cord-022561-rv5j1201	2684	24	antigen	antigen	NN
cord-022561-rv5j1201	2684	25	receptor	receptor	NN
cord-022561-rv5j1201	2684	26	rearrangement	rearrangement	NN
cord-022561-rv5j1201	2684	27	[	[	-LRB-
cord-022561-rv5j1201	2684	28	PARR	PARR	NNP
cord-022561-rv5j1201	2684	29	]	]	-RRB-
cord-022561-rv5j1201	2684	30	)	)	-RRB-
cord-022561-rv5j1201	2684	31	to	to	TO
cord-022561-rv5j1201	2684	32	confirm	confirm	VB
cord-022561-rv5j1201	2684	33	a	a	DT
cord-022561-rv5j1201	2684	34	clonal	clonal	JJ
cord-022561-rv5j1201	2684	35	neoplasm	neoplasm	NN
cord-022561-rv5j1201	2684	36	.	.	.
cord-022561-rv5j1201	2685	1	Transmural	Transmural	NNP
cord-022561-rv5j1201	2685	2	T	T	NNP
cord-022561-rv5j1201	2685	3	cell	cell	NN
cord-022561-rv5j1201	2685	4	lymphomas	lymphoma	NNS
cord-022561-rv5j1201	2685	5	also	also	RB
cord-022561-rv5j1201	2685	6	occur	occur	VBP
cord-022561-rv5j1201	2685	7	focally	focally	RB
cord-022561-rv5j1201	2685	8	or	or	CC
cord-022561-rv5j1201	2685	9	multifocally	multifocally	RB
cord-022561-rv5j1201	2685	10	in	in	IN
cord-022561-rv5j1201	2685	11	the	the	DT
cord-022561-rv5j1201	2685	12	small	small	JJ
cord-022561-rv5j1201	2685	13	intestine	intestine	NN
cord-022561-rv5j1201	2685	14	of	of	IN
cord-022561-rv5j1201	2685	15	cats	cat	NNS
cord-022561-rv5j1201	2685	16	(	(	-LRB-
cord-022561-rv5j1201	2685	17	best	best	RB
cord-022561-rv5j1201	2685	18	classified	classify	VBN
cord-022561-rv5j1201	2685	19	as	as	IN
cord-022561-rv5j1201	2685	20	enteropathy	enteropathy	NNP
cord-022561-rv5j1201	2685	21	-	-	HYPH
cord-022561-rv5j1201	2685	22	associated	associate	VBN
cord-022561-rv5j1201	2685	23	T	T	NNP
cord-022561-rv5j1201	2685	24	cell	cell	NN
cord-022561-rv5j1201	2685	25	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2685	26	type	type	NN
cord-022561-rv5j1201	2685	27	I	I	NNP
cord-022561-rv5j1201	2685	28	)	)	-RRB-
cord-022561-rv5j1201	2685	29	and	and	CC
cord-022561-rv5j1201	2685	30	by	by	IN
cord-022561-rv5j1201	2685	31	definition	definition	NN
cord-022561-rv5j1201	2685	32	must	must	MD
cord-022561-rv5j1201	2685	33	extend	extend	VB
cord-022561-rv5j1201	2685	34	into	into	IN
cord-022561-rv5j1201	2685	35	the	the	DT
cord-022561-rv5j1201	2685	36	submucosa	submucosa	NNP
cord-022561-rv5j1201	2685	37	and	and	CC
cord-022561-rv5j1201	2685	38	muscularis	muscularis	NNP
cord-022561-rv5j1201	2685	39	.	.	.
cord-022561-rv5j1201	2686	1	Some	some	DT
cord-022561-rv5j1201	2686	2	tumors	tumor	NNS
cord-022561-rv5j1201	2686	3	invade	invade	VBP
cord-022561-rv5j1201	2686	4	the	the	DT
cord-022561-rv5j1201	2686	5	serosa	serosa	JJ
cord-022561-rv5j1201	2686	6	and	and	CC
cord-022561-rv5j1201	2686	7	adjacent	adjacent	JJ
cord-022561-rv5j1201	2686	8	mesentery	mesentery	NN
cord-022561-rv5j1201	2686	9	.	.	.
cord-022561-rv5j1201	2687	1	T	t	NN
cord-022561-rv5j1201	2687	2	cell	cell	NN
cord-022561-rv5j1201	2687	3	large	large	JJ
cord-022561-rv5j1201	2687	4	granular	granular	JJ
cord-022561-rv5j1201	2687	5	lymphocyte	lymphocyte	NN
cord-022561-rv5j1201	2688	1	(	(	-LRB-
cord-022561-rv5j1201	2688	2	LGL	LGL	NNP
cord-022561-rv5j1201	2688	3	)	)	-RRB-
cord-022561-rv5j1201	2688	4	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2688	5	is	be	VBZ
cord-022561-rv5j1201	2688	6	often	often	RB
cord-022561-rv5j1201	2688	7	diagnosed	diagnose	VBN
cord-022561-rv5j1201	2688	8	,	,	,
cord-022561-rv5j1201	2688	9	and	and	CC
cord-022561-rv5j1201	2688	10	the	the	DT
cord-022561-rv5j1201	2688	11	intestinal	intestinal	JJ
cord-022561-rv5j1201	2688	12	segments	segment	NNS
cord-022561-rv5j1201	2688	13	orad	orad	RB
cord-022561-rv5j1201	2688	14	and	and	CC
cord-022561-rv5j1201	2688	15	aborad	aborad	NNP
cord-022561-rv5j1201	2688	16	to	to	IN
cord-022561-rv5j1201	2688	17	the	the	DT
cord-022561-rv5j1201	2688	18	transmural	transmural	NNP
cord-022561-rv5j1201	2688	19	mass	mass	NN
cord-022561-rv5j1201	2688	20	may	may	MD
cord-022561-rv5j1201	2688	21	also	also	RB
cord-022561-rv5j1201	2688	22	have	have	VB
cord-022561-rv5j1201	2688	23	mucosal	mucosal	JJ
cord-022561-rv5j1201	2688	24	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2688	25	.	.	.
cord-022561-rv5j1201	2689	1	Gastrointestinal	gastrointestinal	JJ
cord-022561-rv5j1201	2689	2	B	b	NN
cord-022561-rv5j1201	2689	3	cell	cell	NN
cord-022561-rv5j1201	2689	4	lymphomas	lymphoma	NNS
cord-022561-rv5j1201	2689	5	are	be	VBP
cord-022561-rv5j1201	2689	6	less	less	RBR
cord-022561-rv5j1201	2689	7	prevalent	prevalent	JJ
cord-022561-rv5j1201	2689	8	in	in	IN
cord-022561-rv5j1201	2689	9	cats	cat	NNS
cord-022561-rv5j1201	2689	10	but	but	CC
cord-022561-rv5j1201	2689	11	occur	occur	VBP
cord-022561-rv5j1201	2689	12	in	in	IN
cord-022561-rv5j1201	2689	13	the	the	DT
cord-022561-rv5j1201	2689	14	stomach	stomach	NN
cord-022561-rv5j1201	2689	15	,	,	,
cord-022561-rv5j1201	2689	16	jejunum	jejunum	NNS
cord-022561-rv5j1201	2689	17	,	,	,
cord-022561-rv5j1201	2689	18	and	and	CC
cord-022561-rv5j1201	2689	19	ileocecocolic	ileocecocolic	NNP
cord-022561-rv5j1201	2689	20	region	region	NN
cord-022561-rv5j1201	2689	21	as	as	IN
cord-022561-rv5j1201	2689	22	transmural	transmural	NNP
cord-022561-rv5j1201	2689	23	lesions	lesion	NNS
cord-022561-rv5j1201	2689	24	.	.	.
cord-022561-rv5j1201	2690	1	Most	Most	JJS
cord-022561-rv5j1201	2690	2	are	be	VBP
cord-022561-rv5j1201	2690	3	diagnosed	diagnose	VBN
cord-022561-rv5j1201	2690	4	as	as	IN
cord-022561-rv5j1201	2690	5	diffuse	diffuse	JJ
cord-022561-rv5j1201	2690	6	large	large	JJ
cord-022561-rv5j1201	2690	7	B	b	NN
cord-022561-rv5j1201	2690	8	cell	cell	NN
cord-022561-rv5j1201	2690	9	lymphomas	lymphoma	NNS
cord-022561-rv5j1201	2690	10	.	.	.
cord-022561-rv5j1201	2691	1	Lymphomas	lymphoma	NNS
cord-022561-rv5j1201	2691	2	in	in	IN
cord-022561-rv5j1201	2691	3	other	other	JJ
cord-022561-rv5j1201	2691	4	sites	site	NNS
cord-022561-rv5j1201	2691	5	also	also	RB
cord-022561-rv5j1201	2691	6	occur	occur	VBP
cord-022561-rv5j1201	2691	7	less	less	RBR
cord-022561-rv5j1201	2691	8	frequently	frequently	RB
cord-022561-rv5j1201	2691	9	in	in	IN
cord-022561-rv5j1201	2691	10	cats	cat	NNS
cord-022561-rv5j1201	2691	11	.	.	.
cord-022561-rv5j1201	2692	1	The	the	DT
cord-022561-rv5j1201	2692	2	upper	upper	JJ
cord-022561-rv5j1201	2692	3	respiratory	respiratory	JJ
cord-022561-rv5j1201	2692	4	tract	tract	NN
cord-022561-rv5j1201	2692	5	(	(	-LRB-
cord-022561-rv5j1201	2692	6	nasal	nasal	NN
cord-022561-rv5j1201	2692	7	and/or	and/or	CC
cord-022561-rv5j1201	2692	8	nasopharyngeal	nasopharyngeal	JJ
cord-022561-rv5j1201	2692	9	region	region	NN
cord-022561-rv5j1201	2692	10	)	)	-RRB-
cord-022561-rv5j1201	2692	11	is	be	VBZ
cord-022561-rv5j1201	2692	12	a	a	DT
cord-022561-rv5j1201	2692	13	relatively	relatively	RB
cord-022561-rv5j1201	2692	14	rare	rare	JJ
cord-022561-rv5j1201	2692	15	site	site	NN
cord-022561-rv5j1201	2692	16	for	for	IN
cord-022561-rv5j1201	2692	17	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2692	18	.	.	.
cord-022561-rv5j1201	2693	1	However	however	RB
cord-022561-rv5j1201	2693	2	,	,	,
cord-022561-rv5j1201	2693	3	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2693	4	is	be	VBZ
cord-022561-rv5j1201	2693	5	the	the	DT
cord-022561-rv5j1201	2693	6	most	most	RBS
cord-022561-rv5j1201	2693	7	common	common	JJ
cord-022561-rv5j1201	2693	8	primary	primary	JJ
cord-022561-rv5j1201	2693	9	nasal	nasal	NN
cord-022561-rv5j1201	2693	10	tumor	tumor	NN
cord-022561-rv5j1201	2693	11	,	,	,
cord-022561-rv5j1201	2693	12	and	and	CC
cord-022561-rv5j1201	2693	13	diffuse	diffuse	VB
cord-022561-rv5j1201	2693	14	large	large	JJ
cord-022561-rv5j1201	2693	15	B	b	NN
cord-022561-rv5j1201	2693	16	cell	cell	NN
cord-022561-rv5j1201	2693	17	lymphomas	lymphoma	NNS
cord-022561-rv5j1201	2693	18	(	(	-LRB-
cord-022561-rv5j1201	2693	19	of	of	IN
cord-022561-rv5j1201	2693	20	immunoblastic	immunoblastic	JJ
cord-022561-rv5j1201	2693	21	type	type	NN
cord-022561-rv5j1201	2693	22	)	)	-RRB-
cord-022561-rv5j1201	2693	23	are	be	VBP
cord-022561-rv5j1201	2693	24	the	the	DT
cord-022561-rv5j1201	2693	25	predominant	predominant	JJ
cord-022561-rv5j1201	2693	26	subtype	subtype	NN
cord-022561-rv5j1201	2693	27	.	.	.
cord-022561-rv5j1201	2694	1	Both	both	DT
cord-022561-rv5j1201	2694	2	cutaneous	cutaneous	JJ
cord-022561-rv5j1201	2694	3	(	(	-LRB-
cord-022561-rv5j1201	2694	4	cutaneous	cutaneous	JJ
cord-022561-rv5j1201	2694	5	T	T	NNP
cord-022561-rv5j1201	2694	6	cell	cell	NN
cord-022561-rv5j1201	2694	7	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2694	8	)	)	-RRB-
cord-022561-rv5j1201	2694	9	and	and	CC
cord-022561-rv5j1201	2694	10	subcutaneous	subcutaneous	JJ
cord-022561-rv5j1201	2694	11	lymphomas	lymphoma	NNS
cord-022561-rv5j1201	2694	12	(	(	-LRB-
cord-022561-rv5j1201	2694	13	usually	usually	RB
cord-022561-rv5j1201	2694	14	large	large	JJ
cord-022561-rv5j1201	2694	15	cell	cell	NN
cord-022561-rv5j1201	2694	16	lymphomas	lymphoma	NNS
cord-022561-rv5j1201	2694	17	)	)	-RRB-
cord-022561-rv5j1201	2694	18	are	be	VBP
cord-022561-rv5j1201	2694	19	rare	rare	JJ
cord-022561-rv5j1201	2694	20	.	.	.
cord-022561-rv5j1201	2695	1	Presumed	presume	VBN
cord-022561-rv5j1201	2695	2	solitary	solitary	JJ
cord-022561-rv5j1201	2695	3	ocular	ocular	JJ
cord-022561-rv5j1201	2695	4	lymphomas	lymphoma	NNS
cord-022561-rv5j1201	2695	5	have	have	VBP
cord-022561-rv5j1201	2695	6	also	also	RB
cord-022561-rv5j1201	2695	7	been	be	VBN
cord-022561-rv5j1201	2695	8	reported	report	VBN
cord-022561-rv5j1201	2695	9	.	.	.
cord-022561-rv5j1201	2696	1	T	T	NNP
cord-022561-rv5j1201	2696	2	cell	cell	NN
cord-022561-rv5j1201	2696	3	-	-	HYPH
cord-022561-rv5j1201	2696	4	rich	rich	JJ
cord-022561-rv5j1201	2696	5	large	large	JJ
cord-022561-rv5j1201	2696	6	B	b	NN
cord-022561-rv5j1201	2696	7	cell	cell	NN
cord-022561-rv5j1201	2696	8	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2696	9	,	,	,
cord-022561-rv5j1201	2696	10	also	also	RB
cord-022561-rv5j1201	2696	11	referred	refer	VBD
cord-022561-rv5j1201	2696	12	to	to	IN
cord-022561-rv5j1201	2696	13	as	as	IN
cord-022561-rv5j1201	2696	14	feline	feline	JJ
cord-022561-rv5j1201	2696	15	Hodgkin	Hodgkin	NNP
cord-022561-rv5j1201	2696	16	-	-	HYPH
cord-022561-rv5j1201	2696	17	like	like	JJ
cord-022561-rv5j1201	2696	18	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2696	19	in	in	IN
cord-022561-rv5j1201	2696	20	some	some	DT
cord-022561-rv5j1201	2696	21	studies	study	NNS
cord-022561-rv5j1201	2696	22	,	,	,
cord-022561-rv5j1201	2696	23	is	be	VBZ
cord-022561-rv5j1201	2696	24	composed	compose	VBN
cord-022561-rv5j1201	2696	25	of	of	IN
cord-022561-rv5j1201	2696	26	a	a	DT
cord-022561-rv5j1201	2696	27	mixture	mixture	NN
cord-022561-rv5j1201	2696	28	of	of	IN
cord-022561-rv5j1201	2696	29	reactive	reactive	JJ
cord-022561-rv5j1201	2696	30	small	small	JJ
cord-022561-rv5j1201	2696	31	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	2696	32	and	and	CC
cord-022561-rv5j1201	2696	33	large	large	JJ
cord-022561-rv5j1201	2696	34	neoplastic	neoplastic	JJ
cord-022561-rv5j1201	2696	35	B	b	NN
cord-022561-rv5j1201	2696	36	lymphocytes	lymphocyte	NNS
cord-022561-rv5j1201	2696	37	,	,	,
cord-022561-rv5j1201	2696	38	many	many	JJ
cord-022561-rv5j1201	2696	39	of	of	IN
cord-022561-rv5j1201	2696	40	which	which	WDT
cord-022561-rv5j1201	2696	41	may	may	MD
cord-022561-rv5j1201	2696	42	be	be	VB
cord-022561-rv5j1201	2696	43	binucleated	binucleate	VBN
cord-022561-rv5j1201	2696	44	and/or	and/or	CC
cord-022561-rv5j1201	2696	45	have	have	VB
cord-022561-rv5j1201	2696	46	prominent	prominent	JJ
cord-022561-rv5j1201	2696	47	nucleoli	nucleolus	NNS
cord-022561-rv5j1201	2696	48	(	(	-LRB-
cord-022561-rv5j1201	2696	49	thus	thus	RB
cord-022561-rv5j1201	2696	50	resembling	resemble	VBG
cord-022561-rv5j1201	2696	51	the	the	DT
cord-022561-rv5j1201	2696	52	Reed	Reed	NNP
cord-022561-rv5j1201	2696	53	-	-	HYPH
cord-022561-rv5j1201	2696	54	Sternberg	Sternberg	NNP
cord-022561-rv5j1201	2696	55	cells	cell	NNS
cord-022561-rv5j1201	2696	56	of	of	IN
cord-022561-rv5j1201	2696	57	human	human	JJ
cord-022561-rv5j1201	2696	58	Hodgkin	Hodgkin	NNP
cord-022561-rv5j1201	2696	59	's	's	POS
cord-022561-rv5j1201	2696	60	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2696	61	)	)	-RRB-
cord-022561-rv5j1201	2696	62	.	.	.
cord-022561-rv5j1201	2697	1	This	this	DT
cord-022561-rv5j1201	2697	2	disease	disease	NN
cord-022561-rv5j1201	2697	3	is	be	VBZ
cord-022561-rv5j1201	2697	4	typically	typically	RB
cord-022561-rv5j1201	2697	5	characterized	characterize	VBN
cord-022561-rv5j1201	2697	6	by	by	IN
cord-022561-rv5j1201	2697	7	a	a	DT
cord-022561-rv5j1201	2697	8	distinctive	distinctive	JJ
cord-022561-rv5j1201	2697	9	clinical	clinical	JJ
cord-022561-rv5j1201	2697	10	presentation	presentation	NN
cord-022561-rv5j1201	2697	11	of	of	IN
cord-022561-rv5j1201	2697	12	an	an	DT
cord-022561-rv5j1201	2697	13	indolent	indolent	JJ
cord-022561-rv5j1201	2697	14	unilateral	unilateral	JJ
cord-022561-rv5j1201	2697	15	neoplasm	neoplasm	NN
cord-022561-rv5j1201	2697	16	of	of	IN
cord-022561-rv5j1201	2697	17	the	the	DT
cord-022561-rv5j1201	2697	18	cervical	cervical	JJ
cord-022561-rv5j1201	2697	19	lymph	lymph	NN
cord-022561-rv5j1201	2697	20	nodes	node	NNS
cord-022561-rv5j1201	2697	21	,	,	,
cord-022561-rv5j1201	2697	22	which	which	WDT
cord-022561-rv5j1201	2697	23	spreads	spread	VBZ
cord-022561-rv5j1201	2697	24	slowly	slowly	RB
cord-022561-rv5j1201	2697	25	to	to	IN
cord-022561-rv5j1201	2697	26	adjacent	adjacent	JJ
cord-022561-rv5j1201	2697	27	nodes	node	NNS
cord-022561-rv5j1201	2697	28	within	within	IN
cord-022561-rv5j1201	2697	29	the	the	DT
cord-022561-rv5j1201	2697	30	chain	chain	NN
cord-022561-rv5j1201	2697	31	.	.	.
cord-022561-rv5j1201	2698	1	However	however	RB
cord-022561-rv5j1201	2698	2	,	,	,
cord-022561-rv5j1201	2698	3	a	a	DT
cord-022561-rv5j1201	2698	4	proportion	proportion	NN
cord-022561-rv5j1201	2698	5	of	of	IN
cord-022561-rv5j1201	2698	6	cases	case	NNS
cord-022561-rv5j1201	2698	7	may	may	MD
cord-022561-rv5j1201	2698	8	go	go	VB
cord-022561-rv5j1201	2698	9	on	on	RP
cord-022561-rv5j1201	2698	10	to	to	TO
cord-022561-rv5j1201	2698	11	develop	develop	VB
cord-022561-rv5j1201	2698	12	into	into	IN
cord-022561-rv5j1201	2698	13	a	a	DT
cord-022561-rv5j1201	2698	14	more	more	RBR
cord-022561-rv5j1201	2698	15	aggressive	aggressive	JJ
cord-022561-rv5j1201	2698	16	multicentric	multicentric	NN
cord-022561-rv5j1201	2698	17	large	large	JJ
cord-022561-rv5j1201	2698	18	to	to	IN
cord-022561-rv5j1201	2698	19	anaplastic	anaplastic	JJ
cord-022561-rv5j1201	2698	20	B	b	NN
cord-022561-rv5j1201	2698	21	lymphocyte	lymphocyte	NN
cord-022561-rv5j1201	2698	22	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2698	23	that	that	WDT
cord-022561-rv5j1201	2698	24	can	can	MD
cord-022561-rv5j1201	2698	25	affect	affect	VB
cord-022561-rv5j1201	2698	26	peripheral	peripheral	JJ
cord-022561-rv5j1201	2698	27	and	and	CC
cord-022561-rv5j1201	2698	28	central	central	JJ
cord-022561-rv5j1201	2698	29	nodes	node	NNS
cord-022561-rv5j1201	2698	30	and	and	CC
cord-022561-rv5j1201	2698	31	multiple	multiple	JJ
cord-022561-rv5j1201	2698	32	organs	organ	NNS
cord-022561-rv5j1201	2698	33	.	.	.
cord-022561-rv5j1201	2699	1	Suggested	suggest	VBN
cord-022561-rv5j1201	2699	2	Readings	reading	NNS
cord-022561-rv5j1201	2699	3	are	be	VBP
cord-022561-rv5j1201	2699	4	available	available	JJ
cord-022561-rv5j1201	2699	5	at	at	IN
cord-022561-rv5j1201	2699	6	www.expertconsult.com	www.expertconsult.com	ADD
cord-022561-rv5j1201	2699	7	.	.	.
cord-022561-rv5j1201	2700	1	A	a	DT
cord-022561-rv5j1201	2700	2	B	b	NN
cord-022561-rv5j1201	2700	3	discovered	discover	VBN
cord-022561-rv5j1201	2700	4	in	in	IN
cord-022561-rv5j1201	2700	5	domestic	domestic	JJ
cord-022561-rv5j1201	2700	6	cats	cat	NNS
cord-022561-rv5j1201	2700	7	with	with	IN
cord-022561-rv5j1201	2700	8	a	a	DT
cord-022561-rv5j1201	2700	9	16	16	CD
cord-022561-rv5j1201	2700	10	%	%	NN
cord-022561-rv5j1201	2700	11	prevalence	prevalence	NN
cord-022561-rv5j1201	2700	12	in	in	IN
cord-022561-rv5j1201	2700	13	North	North	NNP
cord-022561-rv5j1201	2700	14	America	America	NNP
cord-022561-rv5j1201	2700	15	,	,	,
cord-022561-rv5j1201	2700	16	and	and	CC
cord-022561-rv5j1201	2700	17	further	further	JJ
cord-022561-rv5j1201	2700	18	studies	study	NNS
cord-022561-rv5j1201	2700	19	to	to	TO
cord-022561-rv5j1201	2700	20	investigate	investigate	VB
cord-022561-rv5j1201	2700	21	its	-PRON-	PRP$
cord-022561-rv5j1201	2700	22	role	role	NN
cord-022561-rv5j1201	2700	23	in	in	IN
cord-022561-rv5j1201	2700	24	lymphomagenesis	lymphomagenesi	NNS
cord-022561-rv5j1201	2700	25	are	be	VBP
cord-022561-rv5j1201	2700	26	needed	need	VBN
cord-022561-rv5j1201	2700	27	.	.	.
cord-022561-rv5j1201	2701	1	The	the	DT
cord-022561-rv5j1201	2701	2	overall	overall	JJ
cord-022561-rv5j1201	2701	3	incidence	incidence	NN
cord-022561-rv5j1201	2701	4	of	of	IN
cord-022561-rv5j1201	2701	5	feline	feline	JJ
cord-022561-rv5j1201	2701	6	lymphomas	lymphoma	NNS
cord-022561-rv5j1201	2701	7	has	have	VBZ
cord-022561-rv5j1201	2701	8	increased	increase	VBN
cord-022561-rv5j1201	2701	9	,	,	,
cord-022561-rv5j1201	2701	10	mainly	mainly	RB
cord-022561-rv5j1201	2701	11	due	due	IN
cord-022561-rv5j1201	2701	12	to	to	IN
cord-022561-rv5j1201	2701	13	an	an	DT
cord-022561-rv5j1201	2701	14	increase	increase	NN
cord-022561-rv5j1201	2701	15	in	in	IN
cord-022561-rv5j1201	2701	16	gastrointestinal	gastrointestinal	JJ
cord-022561-rv5j1201	2701	17	lymphomas	lymphoma	NNS
cord-022561-rv5j1201	2701	18	.	.	.
cord-022561-rv5j1201	2702	1	Mucosal	Mucosal	NNP
cord-022561-rv5j1201	2702	2	T	T	NNP
cord-022561-rv5j1201	2702	3	cell	cell	NN
cord-022561-rv5j1201	2702	4	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2702	5	,	,	,
cord-022561-rv5j1201	2702	6	also	also	RB
cord-022561-rv5j1201	2702	7	known	know	VBN
cord-022561-rv5j1201	2702	8	as	as	IN
cord-022561-rv5j1201	2702	9	enteropathy	enteropathy	NNP
cord-022561-rv5j1201	2702	10	-	-	HYPH
cord-022561-rv5j1201	2702	11	associated	associate	VBN
cord-022561-rv5j1201	2702	12	T	T	NNP
cord-022561-rv5j1201	2702	13	cell	cell	NN
cord-022561-rv5j1201	2702	14	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2702	15	(	(	-LRB-
cord-022561-rv5j1201	2702	16	EATCL	EATCL	NNP
cord-022561-rv5j1201	2702	17	type	type	NN
cord-022561-rv5j1201	2702	18	II	II	NNP
cord-022561-rv5j1201	2702	19	)	)	-RRB-
cord-022561-rv5j1201	2702	20	,	,	,
cord-022561-rv5j1201	2702	21	is	be	VBZ
cord-022561-rv5j1201	2702	22	the	the	DT
cord-022561-rv5j1201	2702	23	most	most	RBS
cord-022561-rv5j1201	2702	24	common	common	JJ
cord-022561-rv5j1201	2702	25	and	and	CC
cord-022561-rv5j1201	2702	26	arises	arise	VBZ
cord-022561-rv5j1201	2702	27	from	from	IN
cord-022561-rv5j1201	2702	28	diffuse	diffuse	JJ
cord-022561-rv5j1201	2702	29	MALT	MALT	NNP
cord-022561-rv5j1201	2702	30	partial	partial	JJ
cord-022561-rv5j1201	2702	31	thromboplastin	thromboplastin	NNP
cord-022561-rv5j1201	2702	32	time	time	NN
cord-022561-rv5j1201	2702	33	(	(	-LRB-
cord-022561-rv5j1201	2702	34	aPTT	aPTT	NNP
cord-022561-rv5j1201	2702	35	or	or	CC
cord-022561-rv5j1201	2702	36	PTT	PTT	NNP
cord-022561-rv5j1201	2702	37	)	)	-RRB-
cord-022561-rv5j1201	2703	1	•	•	NNP
cord-022561-rv5j1201	2704	1	Required	require	VBN
cord-022561-rv5j1201	2704	2	sample	sample	NN
cord-022561-rv5j1201	2704	3	:	:	:
cord-022561-rv5j1201	2705	1	citrated	citrated	NNP
cord-022561-rv5j1201	2705	2	plasma	plasma	NNP
cord-022561-rv5j1201	2706	1	•	•	NNP
cord-022561-rv5j1201	2707	1	Measures	measure	NNS
cord-022561-rv5j1201	2707	2	time	time	NN
cord-022561-rv5j1201	2707	3	for	for	IN
cord-022561-rv5j1201	2707	4	fibrin	fibrin	NN
cord-022561-rv5j1201	2707	5	clot	clot	NN
cord-022561-rv5j1201	2707	6	formation	formation	NN
cord-022561-rv5j1201	2707	7	after	after	IN
cord-022561-rv5j1201	2707	8	addition	addition	NN
cord-022561-rv5j1201	2707	9	of	of	IN
cord-022561-rv5j1201	2707	10	a	a	DT
cord-022561-rv5j1201	2707	11	contact	contact	NN
cord-022561-rv5j1201	2707	12	activator	activator	NN
cord-022561-rv5j1201	2707	13	,	,	,
cord-022561-rv5j1201	2707	14	calcium	calcium	NN
cord-022561-rv5j1201	2707	15	,	,	,
cord-022561-rv5j1201	2707	16	and	and	CC
cord-022561-rv5j1201	2707	17	a	a	DT
cord-022561-rv5j1201	2707	18	substitute	substitute	NN
cord-022561-rv5j1201	2707	19	for	for	IN
cord-022561-rv5j1201	2707	20	platelet	platelet	NN
cord-022561-rv5j1201	2707	21	phospholipid	phospholipid	NN
cord-022561-rv5j1201	2707	22	•	•	NNP
cord-022561-rv5j1201	2708	1	Deficiencies	deficiency	NNS
cord-022561-rv5j1201	2708	2	/	/	SYM
cord-022561-rv5j1201	2708	3	dysfunction	dysfunction	NN
cord-022561-rv5j1201	2708	4	in	in	IN
cord-022561-rv5j1201	2708	5	intrinsic	intrinsic	JJ
cord-022561-rv5j1201	2708	6	and/or	and/or	CC
cord-022561-rv5j1201	2708	7	common	common	JJ
cord-022561-rv5j1201	2708	8	coagulation	coagulation	NN
cord-022561-rv5j1201	2708	9	pathway	pathway	NN
cord-022561-rv5j1201	2708	10	(	(	-LRB-
cord-022561-rv5j1201	2708	11	all	all	DT
cord-022561-rv5j1201	2708	12	factors	factor	NNS
cord-022561-rv5j1201	2708	13	except	except	IN
cord-022561-rv5j1201	2708	14	for	for	IN
cord-022561-rv5j1201	2708	15	VII	VII	NNP
cord-022561-rv5j1201	2708	16	and	and	CC
cord-022561-rv5j1201	2708	17	XIII	XIII	NNP
cord-022561-rv5j1201	2708	18	)	)	-RRB-
cord-022561-rv5j1201	2708	19	causes	cause	VBZ
cord-022561-rv5j1201	2708	20	prolongation	prolongation	NN
cord-022561-rv5j1201	2708	21	of	of	IN
cord-022561-rv5j1201	2708	22	PTT	PTT	NNP
cord-022561-rv5j1201	2708	23	•	•	NNP
cord-022561-rv5j1201	2709	1	Insensitive	insensitive	JJ
cord-022561-rv5j1201	2709	2	test	test	NN
cord-022561-rv5j1201	2709	3	-	-	HYPH
cord-022561-rv5j1201	2709	4	prolongation	prolongation	NN
cord-022561-rv5j1201	2709	5	requires	require	VBZ
cord-022561-rv5j1201	2709	6	70	70	CD
cord-022561-rv5j1201	2709	7	%	%	NN
cord-022561-rv5j1201	2709	8	deficiency	deficiency	NN
cord-022561-rv5j1201	2709	9	.	.	.
cord-022561-rv5j1201	2710	1	•	•	NNP
cord-022561-rv5j1201	2711	1	Other	other	JJ
cord-022561-rv5j1201	2711	2	causes	cause	NNS
cord-022561-rv5j1201	2711	3	of	of	IN
cord-022561-rv5j1201	2711	4	prolongation	prolongation	NN
cord-022561-rv5j1201	2711	5	include	include	VBP
cord-022561-rv5j1201	2711	6	polycythemia	polycythemia	NN
cord-022561-rv5j1201	2711	7	(	(	-LRB-
cord-022561-rv5j1201	2711	8	less	less	JJR
cord-022561-rv5j1201	2711	9	plasma	plasma	NN
cord-022561-rv5j1201	2711	10	per	per	IN
cord-022561-rv5j1201	2711	11	unit	unit	NN
cord-022561-rv5j1201	2711	12	volume	volume	NN
cord-022561-rv5j1201	2711	13	,	,	,
cord-022561-rv5j1201	2711	14	so	so	RB
cord-022561-rv5j1201	2711	15	excess	excess	JJ
cord-022561-rv5j1201	2711	16	amount	amount	NN
cord-022561-rv5j1201	2711	17	of	of	IN
cord-022561-rv5j1201	2711	18	citrate	citrate	NN
cord-022561-rv5j1201	2711	19	is	be	VBZ
cord-022561-rv5j1201	2711	20	available	available	JJ
cord-022561-rv5j1201	2711	21	to	to	TO
cord-022561-rv5j1201	2711	22	chelate	chelate	JJ
cord-022561-rv5j1201	2711	23	calcium	calcium	NN
cord-022561-rv5j1201	2711	24	)	)	-RRB-
cord-022561-rv5j1201	2711	25	and	and	CC
cord-022561-rv5j1201	2711	26	heparin	heparin	NN
cord-022561-rv5j1201	2711	27	therapy	therapy	NN
cord-022561-rv5j1201	2711	28	Activated	activate	VBN
cord-022561-rv5j1201	2711	29	clotting	clotting	NN
cord-022561-rv5j1201	2711	30	time	time	NN
cord-022561-rv5j1201	2711	31	(	(	-LRB-
cord-022561-rv5j1201	2711	32	ACT	act	NN
cord-022561-rv5j1201	2711	33	)	)	-RRB-
cord-022561-rv5j1201	2712	1	•	•	NNP
cord-022561-rv5j1201	2713	1	Required	require	VBN
cord-022561-rv5j1201	2713	2	sample	sample	NN
cord-022561-rv5j1201	2713	3	:	:	:
cord-022561-rv5j1201	2713	4	nonanticoagulated	nonanticoagulate	VBN
cord-022561-rv5j1201	2713	5	whole	whole	JJ
cord-022561-rv5j1201	2713	6	blood	blood	NN
cord-022561-rv5j1201	2713	7	in	in	IN
cord-022561-rv5j1201	2713	8	special	special	JJ
cord-022561-rv5j1201	2713	9	ACT	act	NN
cord-022561-rv5j1201	2713	10	tube	tube	NN
cord-022561-rv5j1201	2713	11	(	(	-LRB-
cord-022561-rv5j1201	2713	12	diatomaceous	diatomaceous	NNP
cord-022561-rv5j1201	2713	13	earth	earth	NN
cord-022561-rv5j1201	2713	14	as	as	IN
cord-022561-rv5j1201	2713	15	contact	contact	NN
cord-022561-rv5j1201	2713	16	activator	activator	NN
cord-022561-rv5j1201	2713	17	)	)	-RRB-
cord-022561-rv5j1201	2713	18	Used	use	VBN
cord-022561-rv5j1201	2713	19	in	in	IN
cord-022561-rv5j1201	2713	20	practice	practice	NN
cord-022561-rv5j1201	2713	21	setting	setting	NN
cord-022561-rv5j1201	2713	22	-	-	HYPH
cord-022561-rv5j1201	2713	23	performed	perform	VBN
cord-022561-rv5j1201	2713	24	by	by	IN
cord-022561-rv5j1201	2713	25	warming	warm	VBG
cord-022561-rv5j1201	2713	26	sample	sample	NN
cord-022561-rv5j1201	2713	27	to	to	IN
cord-022561-rv5j1201	2713	28	body	body	NN
cord-022561-rv5j1201	2713	29	temperature	temperature	NN
cord-022561-rv5j1201	2713	30	,	,	,
cord-022561-rv5j1201	2713	31	monitoring	monitor	VBG
cord-022561-rv5j1201	2713	32	for	for	IN
cord-022561-rv5j1201	2713	33	clot	clot	NN
cord-022561-rv5j1201	2713	34	formation	formation	NN
cord-022561-rv5j1201	2714	1	;	;	:
cord-022561-rv5j1201	2714	2	normal	normal	JJ
cord-022561-rv5j1201	2714	3	clotting	clotting	NN
cord-022561-rv5j1201	2714	4	times	time	NNS
cord-022561-rv5j1201	2714	5	are	be	VBP
cord-022561-rv5j1201	2714	6	within	within	IN
cord-022561-rv5j1201	2714	7	60	60	CD
cord-022561-rv5j1201	2714	8	to	to	TO
cord-022561-rv5j1201	2714	9	90	90	CD
cord-022561-rv5j1201	2714	10	seconds	second	NNS
cord-022561-rv5j1201	2714	11	in	in	IN
cord-022561-rv5j1201	2714	12	dogs	dog	NNS
cord-022561-rv5j1201	2714	13	,	,	,
cord-022561-rv5j1201	2714	14	165	165	CD
cord-022561-rv5j1201	2714	15	seconds	second	NNS
cord-022561-rv5j1201	2714	16	in	in	IN
cord-022561-rv5j1201	2714	17	cats	cat	NNS
cord-022561-rv5j1201	2714	18	•	•	XX
cord-022561-rv5j1201	2715	1	Less	less	RBR
cord-022561-rv5j1201	2715	2	sensitive	sensitive	JJ
cord-022561-rv5j1201	2715	3	version	version	NN
cord-022561-rv5j1201	2715	4	of	of	IN
cord-022561-rv5j1201	2715	5	PTT	ptt	NN
cord-022561-rv5j1201	2715	6	-	-	HYPH
cord-022561-rv5j1201	2715	7	prolongation	prolongation	NN
cord-022561-rv5j1201	2715	8	requires	require	VBZ
cord-022561-rv5j1201	2715	9	95	95	CD
cord-022561-rv5j1201	2715	10	%	%	NN
cord-022561-rv5j1201	2715	11	deficiency	deficiency	NN
cord-022561-rv5j1201	2715	12	Severe	severe	JJ
cord-022561-rv5j1201	2715	13	thrombocytopenia	thrombocytopenia	NN
cord-022561-rv5j1201	2715	14	may	may	MD
cord-022561-rv5j1201	2715	15	cause	cause	VB
cord-022561-rv5j1201	2715	16	prolongation	prolongation	NN
cord-022561-rv5j1201	2715	17	.	.	.
cord-022561-rv5j1201	2716	1	•	•	NNP
cord-022561-rv5j1201	2716	2	One	one	CD
cord-022561-rv5j1201	2716	3	-	-	HYPH
cord-022561-rv5j1201	2716	4	stage	stage	NN
cord-022561-rv5j1201	2716	5	prothrombin	prothrombin	NN
cord-022561-rv5j1201	2716	6	time	time	NN
cord-022561-rv5j1201	2716	7	(	(	-LRB-
cord-022561-rv5j1201	2716	8	OSPT	OSPT	NNP
cord-022561-rv5j1201	2716	9	or	or	CC
cord-022561-rv5j1201	2716	10	PT	PT	NNP
cord-022561-rv5j1201	2716	11	)	)	-RRB-
cord-022561-rv5j1201	2717	1	•	•	NNP
cord-022561-rv5j1201	2718	1	Required	require	VBN
cord-022561-rv5j1201	2718	2	sample	sample	NN
cord-022561-rv5j1201	2718	3	:	:	:
cord-022561-rv5j1201	2719	1	citrated	citrated	NNP
cord-022561-rv5j1201	2719	2	plasma	plasma	NNP
cord-022561-rv5j1201	2720	1	•	•	NNP
cord-022561-rv5j1201	2721	1	Measures	measure	NNS
cord-022561-rv5j1201	2721	2	time	time	NN
cord-022561-rv5j1201	2721	3	for	for	IN
cord-022561-rv5j1201	2721	4	fibrin	fibrin	NN
cord-022561-rv5j1201	2721	5	clot	clot	NN
cord-022561-rv5j1201	2721	6	formation	formation	NN
cord-022561-rv5j1201	2721	7	after	after	IN
cord-022561-rv5j1201	2721	8	addition	addition	NN
cord-022561-rv5j1201	2721	9	of	of	IN
cord-022561-rv5j1201	2721	10	tissue	tissue	NN
cord-022561-rv5j1201	2721	11	factor	factor	NN
cord-022561-rv5j1201	2721	12	(	(	-LRB-
cord-022561-rv5j1201	2721	13	TF	TF	NNP
cord-022561-rv5j1201	2721	14	;	;	:
cord-022561-rv5j1201	2721	15	thromboplastin	thromboplastin	NNP
cord-022561-rv5j1201	2721	16	)	)	-RRB-
cord-022561-rv5j1201	2721	17	,	,	,
cord-022561-rv5j1201	2721	18	calcium	calcium	NN
cord-022561-rv5j1201	2721	19	,	,	,
cord-022561-rv5j1201	2721	20	and	and	CC
cord-022561-rv5j1201	2721	21	a	a	DT
cord-022561-rv5j1201	2721	22	substitute	substitute	NN
cord-022561-rv5j1201	2721	23	for	for	IN
cord-022561-rv5j1201	2721	24	platelet	platelet	NN
cord-022561-rv5j1201	2721	25	phospholipid	phospholipid	NN
cord-022561-rv5j1201	2721	26	•	•	NNP
cord-022561-rv5j1201	2721	27	Deficiencies	deficiency	NNS
cord-022561-rv5j1201	2721	28	/	/	SYM
cord-022561-rv5j1201	2721	29	dysfunction	dysfunction	NN
cord-022561-rv5j1201	2721	30	in	in	IN
cord-022561-rv5j1201	2721	31	extrinsic	extrinsic	JJ
cord-022561-rv5j1201	2721	32	(	(	-LRB-
cord-022561-rv5j1201	2721	33	factor	factor	NN
cord-022561-rv5j1201	2721	34	VII	vii	NN
cord-022561-rv5j1201	2721	35	)	)	-RRB-
cord-022561-rv5j1201	2722	1	and/or	and/or	CC
cord-022561-rv5j1201	2723	1	common	common	JJ
cord-022561-rv5j1201	2723	2	coagulation	coagulation	NN
cord-022561-rv5j1201	2723	3	pathway	pathway	NN
cord-022561-rv5j1201	2723	4	cause	cause	NN
cord-022561-rv5j1201	2723	5	prolongation	prolongation	NN
cord-022561-rv5j1201	2723	6	of	of	IN
cord-022561-rv5j1201	2723	7	PT	PT	NNP
cord-022561-rv5j1201	2723	8	•	•	NNP
cord-022561-rv5j1201	2723	9	Insensitive	insensitive	JJ
cord-022561-rv5j1201	2723	10	test	test	NN
cord-022561-rv5j1201	2723	11	-	-	HYPH
cord-022561-rv5j1201	2723	12	prolongation	prolongation	NN
cord-022561-rv5j1201	2723	13	requires	require	VBZ
cord-022561-rv5j1201	2723	14	70	70	CD
cord-022561-rv5j1201	2723	15	%	%	NN
cord-022561-rv5j1201	2723	16	deficiency	deficiency	NN
cord-022561-rv5j1201	2723	17	Proteins	protein	NNS
cord-022561-rv5j1201	2723	18	induced	induce	VBN
cord-022561-rv5j1201	2723	19	by	by	IN
cord-022561-rv5j1201	2723	20	vitamin	vitamin	NN
cord-022561-rv5j1201	2723	21	K	K	NNP
cord-022561-rv5j1201	2723	22	antagonism	antagonism	NN
cord-022561-rv5j1201	2723	23	or	or	CC
cord-022561-rv5j1201	2723	24	absence	absence	NN
cord-022561-rv5j1201	2723	25	(	(	-LRB-
cord-022561-rv5j1201	2723	26	PIVKA	PIVKA	NNP
cord-022561-rv5j1201	2723	27	)	)	-RRB-
cord-022561-rv5j1201	2723	28	test	test	NN
cord-022561-rv5j1201	2724	1	•	•	NNP
cord-022561-rv5j1201	2725	1	Required	require	VBN
cord-022561-rv5j1201	2725	2	sample	sample	NN
cord-022561-rv5j1201	2725	3	:	:	:
cord-022561-rv5j1201	2725	4	citrated	citrate	VBN
cord-022561-rv5j1201	2725	5	plasma	plasma	NN
cord-022561-rv5j1201	2726	1	•	•	NNP
cord-022561-rv5j1201	2727	1	Essentially	essentially	RB
cord-022561-rv5j1201	2727	2	a	a	DT
cord-022561-rv5j1201	2727	3	version	version	NN
cord-022561-rv5j1201	2727	4	of	of	IN
cord-022561-rv5j1201	2727	5	the	the	DT
cord-022561-rv5j1201	2727	6	PT	PT	NNP
cord-022561-rv5j1201	2727	7	using	use	VBG
cord-022561-rv5j1201	2727	8	an	an	DT
cord-022561-rv5j1201	2727	9	especially	especially	RB
cord-022561-rv5j1201	2727	10	sensitive	sensitive	JJ
cord-022561-rv5j1201	2727	11	thromboplastin	thromboplastin	NNS
cord-022561-rv5j1201	2727	12	reagent	reagent	NN
cord-022561-rv5j1201	2728	1	•	•	NNP
cord-022561-rv5j1201	2728	2	PIVKA	PIVKA	NNP
cord-022561-rv5j1201	2728	3	are	be	VBP
cord-022561-rv5j1201	2728	4	inactive	inactive	JJ
cord-022561-rv5j1201	2728	5	(	(	-LRB-
cord-022561-rv5j1201	2728	6	uncarboxylated	uncarboxylated	JJ
cord-022561-rv5j1201	2728	7	)	)	-RRB-
cord-022561-rv5j1201	2728	8	vitamin	vitamin	NN
cord-022561-rv5j1201	2728	9	K	k	NN
cord-022561-rv5j1201	2728	10	-	-	HYPH
cord-022561-rv5j1201	2728	11	dependent	dependent	JJ
cord-022561-rv5j1201	2728	12	factors	factor	NNS
cord-022561-rv5j1201	2728	13	;	;	:
cord-022561-rv5j1201	2728	14	an	an	DT
cord-022561-rv5j1201	2728	15	increase	increase	NN
cord-022561-rv5j1201	2728	16	in	in	IN
cord-022561-rv5j1201	2728	17	PIVKA	PIVKA	NNP
cord-022561-rv5j1201	2728	18	is	be	VBZ
cord-022561-rv5j1201	2728	19	not	not	RB
cord-022561-rv5j1201	2728	20	specific	specific	JJ
cord-022561-rv5j1201	2728	21	for	for	IN
cord-022561-rv5j1201	2728	22	vitamin	vitamin	NN
cord-022561-rv5j1201	2728	23	-	-	HYPH
cord-022561-rv5j1201	2728	24	K	k	NN
cord-022561-rv5j1201	2728	25	antagonism	antagonism	NN
cord-022561-rv5j1201	2728	26	but	but	CC
cord-022561-rv5j1201	2728	27	may	may	MD
cord-022561-rv5j1201	2728	28	be	be	VB
cord-022561-rv5j1201	2728	29	an	an	DT
cord-022561-rv5j1201	2728	30	earlier	early	JJR
cord-022561-rv5j1201	2728	31	and	and	CC
cord-022561-rv5j1201	2728	32	more	more	RBR
cord-022561-rv5j1201	2728	33	sensitive	sensitive	JJ
cord-022561-rv5j1201	2728	34	detector	detector	NN
cord-022561-rv5j1201	2728	35	than	than	IN
cord-022561-rv5j1201	2728	36	PT	PT	NNP
cord-022561-rv5j1201	2728	37	or	or	CC
cord-022561-rv5j1201	2728	38	PTT	PTT	NNP
cord-022561-rv5j1201	2729	1	•	•	NNP
cord-022561-rv5j1201	2730	1	Thrombin	Thrombin	NNP
cord-022561-rv5j1201	2730	2	time	time	NN
cord-022561-rv5j1201	2730	3	(	(	-LRB-
cord-022561-rv5j1201	2730	4	TT	TT	NNP
cord-022561-rv5j1201	2730	5	)	)	-RRB-
cord-022561-rv5j1201	2731	1	•	•	NNP
cord-022561-rv5j1201	2732	1	Required	require	VBN
cord-022561-rv5j1201	2732	2	sample	sample	NN
cord-022561-rv5j1201	2732	3	:	:	:
cord-022561-rv5j1201	2733	1	citrated	citrated	NNP
cord-022561-rv5j1201	2733	2	plasma	plasma	NNP
cord-022561-rv5j1201	2734	1	•	•	NNP
cord-022561-rv5j1201	2735	1	Measures	measure	NNS
cord-022561-rv5j1201	2735	2	time	time	NN
cord-022561-rv5j1201	2735	3	for	for	IN
cord-022561-rv5j1201	2735	4	fibrin	fibrin	NN
cord-022561-rv5j1201	2735	5	clot	clot	NN
cord-022561-rv5j1201	2735	6	formation	formation	NN
cord-022561-rv5j1201	2735	7	after	after	IN
cord-022561-rv5j1201	2735	8	thrombin	thrombin	NN
cord-022561-rv5j1201	2735	9	(	(	-LRB-
cord-022561-rv5j1201	2735	10	factor	factor	NNP
cord-022561-rv5j1201	2735	11	IIa	IIa	NNP
cord-022561-rv5j1201	2735	12	)	)	-RRB-
cord-022561-rv5j1201	2735	13	is	be	VBZ
cord-022561-rv5j1201	2735	14	added	add	VBN
cord-022561-rv5j1201	2735	15	•	•	NNP
cord-022561-rv5j1201	2735	16	Defects	defect	NNS
cord-022561-rv5j1201	2735	17	directly	directly	RB
cord-022561-rv5j1201	2735	18	involving	involve	VBG
cord-022561-rv5j1201	2735	19	formation	formation	NN
cord-022561-rv5j1201	2735	20	and/or	and/or	CC
cord-022561-rv5j1201	2735	21	polymerization	polymerization	NN
cord-022561-rv5j1201	2735	22	of	of	IN
cord-022561-rv5j1201	2735	23	fibrin	fibrin	NN
cord-022561-rv5j1201	2735	24	prolong	prolong	VBP
cord-022561-rv5j1201	2735	25	this	this	DT
cord-022561-rv5j1201	2735	26	test	test	NN
cord-022561-rv5j1201	2735	27	(	(	-LRB-
cord-022561-rv5j1201	2735	28	i.e.	i.e.	FW
cord-022561-rv5j1201	2735	29	,	,	,
cord-022561-rv5j1201	2735	30	if	if	IN
cord-022561-rv5j1201	2735	31	the	the	DT
cord-022561-rv5j1201	2735	32	lesion	lesion	NN
cord-022561-rv5j1201	2735	33	is	be	VBZ
cord-022561-rv5j1201	2735	34	upstream	upstream	JJ
cord-022561-rv5j1201	2735	35	of	of	IN
cord-022561-rv5j1201	2735	36	the	the	DT
cord-022561-rv5j1201	2735	37	conversion	conversion	NN
cord-022561-rv5j1201	2735	38	of	of	IN
cord-022561-rv5j1201	2735	39	fibrinogen	fibrinogen	NN
cord-022561-rv5j1201	2735	40	to	to	IN
cord-022561-rv5j1201	2735	41	fibrin	fibrin	NN
cord-022561-rv5j1201	2735	42	,	,	,
cord-022561-rv5j1201	2735	43	the	the	DT
cord-022561-rv5j1201	2735	44	TT	TT	NNP
cord-022561-rv5j1201	2735	45	will	will	MD
cord-022561-rv5j1201	2735	46	be	be	VB
cord-022561-rv5j1201	2735	47	normal	normal	JJ
cord-022561-rv5j1201	2735	48	)	)	-RRB-
cord-022561-rv5j1201	2735	49	.	.	.
cord-022561-rv5j1201	2736	1	Hypofibrinogenemia	Hypofibrinogenemia	NNP
cord-022561-rv5j1201	2736	2	or	or	CC
cord-022561-rv5j1201	2736	3	dysfibrinogenemia	dysfibrinogenemia	NN
cord-022561-rv5j1201	2736	4	causes	cause	VBZ
cord-022561-rv5j1201	2736	5	prolongation	prolongation	NN
cord-022561-rv5j1201	2736	6	of	of	IN
cord-022561-rv5j1201	2736	7	the	the	DT
cord-022561-rv5j1201	2736	8	TT	TT	NNP
cord-022561-rv5j1201	2736	9	Required	require	VBN
cord-022561-rv5j1201	2736	10	sample	sample	NN
cord-022561-rv5j1201	2736	11	:	:	:
cord-022561-rv5j1201	2736	12	citrated	citrate	VBN
cord-022561-rv5j1201	2736	13	plasma	plasma	NN
cord-022561-rv5j1201	2736	14	.	.	.
cord-022561-rv5j1201	2737	1	•	•	NNP
cord-022561-rv5j1201	2738	1	Fibrinogen	fibrinogen	NN
cord-022561-rv5j1201	2738	2	concentration	concentration	NN
cord-022561-rv5j1201	2738	3	measured	measure	VBN
cord-022561-rv5j1201	2738	4	based	base	VBN
cord-022561-rv5j1201	2738	5	on	on	IN
cord-022561-rv5j1201	2738	6	time	time	NN
cord-022561-rv5j1201	2738	7	to	to	IN
cord-022561-rv5j1201	2738	8	clot	clot	NN
cord-022561-rv5j1201	2738	9	formation	formation	NN
cord-022561-rv5j1201	2738	10	after	after	IN
cord-022561-rv5j1201	2738	11	addition	addition	NN
cord-022561-rv5j1201	2738	12	of	of	IN
cord-022561-rv5j1201	2738	13	thrombin	thrombin	NN
cord-022561-rv5j1201	2738	14	;	;	:
cord-022561-rv5j1201	2738	15	this	this	DT
cord-022561-rv5j1201	2738	16	is	be	VBZ
cord-022561-rv5j1201	2738	17	essentially	essentially	RB
cord-022561-rv5j1201	2738	18	the	the	DT
cord-022561-rv5j1201	2738	19	same	same	JJ
cord-022561-rv5j1201	2738	20	as	as	IN
cord-022561-rv5j1201	2738	21	the	the	DT
cord-022561-rv5j1201	2738	22	TT	TT	NNP
cord-022561-rv5j1201	2738	23	mentioned	mention	VBD
cord-022561-rv5j1201	2738	24	earlier	early	RBR
cord-022561-rv5j1201	2738	25	and	and	CC
cord-022561-rv5j1201	2738	26	is	be	VBZ
cord-022561-rv5j1201	2738	27	a	a	DT
cord-022561-rv5j1201	2738	28	more	more	RBR
cord-022561-rv5j1201	2738	29	accurate	accurate	JJ
cord-022561-rv5j1201	2738	30	method	method	NN
cord-022561-rv5j1201	2738	31	than	than	IN
cord-022561-rv5j1201	2738	32	the	the	DT
cord-022561-rv5j1201	2738	33	heat	heat	NN
cord-022561-rv5j1201	2738	34	precipitation	precipitation	NN
cord-022561-rv5j1201	2738	35	method	method	NN
cord-022561-rv5j1201	2739	1	•	•	NNP
cord-022561-rv5j1201	2740	1	Decreased	decrease	VBN
cord-022561-rv5j1201	2740	2	fibrinogen	fibrinogen	NN
cord-022561-rv5j1201	2740	3	may	may	MD
cord-022561-rv5j1201	2740	4	be	be	VB
cord-022561-rv5j1201	2740	5	because	because	IN
cord-022561-rv5j1201	2740	6	of	of	IN
cord-022561-rv5j1201	2740	7	increased	increase	VBN
cord-022561-rv5j1201	2740	8	consumption	consumption	NN
cord-022561-rv5j1201	2740	9	(	(	-LRB-
cord-022561-rv5j1201	2740	10	disseminated	disseminate	VBN
cord-022561-rv5j1201	2740	11	intravascular	intravascular	JJ
cord-022561-rv5j1201	2740	12	coagulation	coagulation	NN
cord-022561-rv5j1201	2740	13	)	)	-RRB-
cord-022561-rv5j1201	2740	14	or	or	CC
cord-022561-rv5j1201	2740	15	decreased	decrease	VBD
cord-022561-rv5j1201	2740	16	production	production	NN
cord-022561-rv5j1201	2740	17	(	(	-LRB-
cord-022561-rv5j1201	2740	18	liver	liver	NN
cord-022561-rv5j1201	2740	19	disease	disease	NN
cord-022561-rv5j1201	2740	20	)	)	-RRB-
cord-022561-rv5j1201	2741	1	Increased	increase	VBN
cord-022561-rv5j1201	2741	2	fibrinogen	fibrinogen	NN
cord-022561-rv5j1201	2741	3	is	be	VBZ
cord-022561-rv5j1201	2741	4	associated	associate	VBN
cord-022561-rv5j1201	2741	5	with	with	IN
cord-022561-rv5j1201	2741	6	inflammation	inflammation	NN
cord-022561-rv5j1201	2741	7	,	,	,
cord-022561-rv5j1201	2741	8	renal	renal	JJ
cord-022561-rv5j1201	2741	9	disease	disease	NN
cord-022561-rv5j1201	2741	10	,	,	,
cord-022561-rv5j1201	2741	11	and	and	CC
cord-022561-rv5j1201	2741	12	dehydration	dehydration	NN
cord-022561-rv5j1201	2741	13	Required	require	VBN
cord-022561-rv5j1201	2741	14	sample	sample	NN
cord-022561-rv5j1201	2741	15	:	:	:
cord-022561-rv5j1201	2741	16	special	special	JJ
cord-022561-rv5j1201	2741	17	FDP	FDP	NNP
cord-022561-rv5j1201	2741	18	tube	tube	NN
cord-022561-rv5j1201	2741	19	.	.	.
cord-022561-rv5j1201	2742	1	•	•	NNP
cord-022561-rv5j1201	2743	1	Used	use	VBN
cord-022561-rv5j1201	2743	2	in	in	IN
cord-022561-rv5j1201	2743	3	the	the	DT
cord-022561-rv5j1201	2743	4	practice	practice	NN
cord-022561-rv5j1201	2743	5	setting	setting	NN
cord-022561-rv5j1201	2743	6	.	.	.
cord-022561-rv5j1201	2744	1	•	•	NNP
cord-022561-rv5j1201	2745	1	Performed	perform	VBN
cord-022561-rv5j1201	2745	2	by	by	IN
cord-022561-rv5j1201	2745	3	adding	add	VBG
cord-022561-rv5j1201	2745	4	blood	blood	NN
cord-022561-rv5j1201	2745	5	to	to	IN
cord-022561-rv5j1201	2745	6	a	a	DT
cord-022561-rv5j1201	2745	7	special	special	JJ
cord-022561-rv5j1201	2745	8	tube	tube	NN
cord-022561-rv5j1201	2745	9	containing	contain	VBG
cord-022561-rv5j1201	2745	10	thrombin	thrombin	NN
cord-022561-rv5j1201	2745	11	and	and	CC
cord-022561-rv5j1201	2745	12	a	a	DT
cord-022561-rv5j1201	2745	13	trypsin	trypsin	NN
cord-022561-rv5j1201	2745	14	inhibitor	inhibitor	NN
cord-022561-rv5j1201	2745	15	(	(	-LRB-
cord-022561-rv5j1201	2745	16	sample	sample	NN
cord-022561-rv5j1201	2745	17	clots	clot	NNS
cord-022561-rv5j1201	2745	18	almost	almost	RB
cord-022561-rv5j1201	2745	19	instantly	instantly	RB
cord-022561-rv5j1201	2745	20	in	in	IN
cord-022561-rv5j1201	2745	21	normal	normal	JJ
cord-022561-rv5j1201	2745	22	dogs	dog	NNS
cord-022561-rv5j1201	2745	23	and	and	CC
cord-022561-rv5j1201	2745	24	cats	cat	NNS
cord-022561-rv5j1201	2745	25	)	)	-RRB-
cord-022561-rv5j1201	2745	26	and	and	CC
cord-022561-rv5j1201	2745	27	incubating	incubate	VBG
cord-022561-rv5j1201	2745	28	two	two	CD
cord-022561-rv5j1201	2745	29	dilutions	dilution	NNS
cord-022561-rv5j1201	2745	30	of	of	IN
cord-022561-rv5j1201	2745	31	serum	serum	NN
cord-022561-rv5j1201	2745	32	(	(	-LRB-
cord-022561-rv5j1201	2745	33	1	1	CD
cord-022561-rv5j1201	2745	34	:	:	SYM
cord-022561-rv5j1201	2745	35	5	5	CD
cord-022561-rv5j1201	2745	36	and	and	CC
cord-022561-rv5j1201	2745	37	1	1	CD
cord-022561-rv5j1201	2745	38	:	:	SYM
cord-022561-rv5j1201	2745	39	20	20	CD
cord-022561-rv5j1201	2745	40	)	)	-RRB-
cord-022561-rv5j1201	2745	41	with	with	IN
cord-022561-rv5j1201	2745	42	polystyrene	polystyrene	NN
cord-022561-rv5j1201	2745	43	latex	latex	NN
cord-022561-rv5j1201	2745	44	particles	particle	NNS
cord-022561-rv5j1201	2745	45	coated	coat	VBN
cord-022561-rv5j1201	2745	46	with	with	IN
cord-022561-rv5j1201	2745	47	sheep	sheep	NN
cord-022561-rv5j1201	2745	48	anti	anti	NNP
cord-022561-rv5j1201	2745	49	-	-	NNP
cord-022561-rv5j1201	2745	50	FDP	FDP	NNP
cord-022561-rv5j1201	2745	51	antibodies	antibody	NNS
cord-022561-rv5j1201	2745	52	(	(	-LRB-
cord-022561-rv5j1201	2745	53	should	should	MD
cord-022561-rv5j1201	2745	54	be	be	VB
cord-022561-rv5j1201	2745	55	negative	negative	JJ
cord-022561-rv5j1201	2745	56	in	in	IN
cord-022561-rv5j1201	2745	57	normal	normal	JJ
cord-022561-rv5j1201	2745	58	dogs	dog	NNS
cord-022561-rv5j1201	2745	59	and	and	CC
cord-022561-rv5j1201	2745	60	cats	cat	NNS
cord-022561-rv5j1201	2746	1	Required	require	VBN
cord-022561-rv5j1201	2746	2	sample	sample	NN
cord-022561-rv5j1201	2746	3	:	:	:
cord-022561-rv5j1201	2746	4	citrated	citrate	VBN
cord-022561-rv5j1201	2746	5	plasma	plasma	NN
cord-022561-rv5j1201	2746	6	.	.	.
cord-022561-rv5j1201	2747	1	•	•	NNP
cord-022561-rv5j1201	2748	1	Latex	latex	NN
cord-022561-rv5j1201	2748	2	agglutination	agglutination	NN
cord-022561-rv5j1201	2748	3	test	test	NN
cord-022561-rv5j1201	2748	4	.	.	.
cord-022561-rv5j1201	2749	1	•	•	NNP
cord-022561-rv5j1201	2750	1	To	to	IN
cord-022561-rv5j1201	2750	2	date	date	NN
cord-022561-rv5j1201	2750	3	,	,	,
cord-022561-rv5j1201	2750	4	only	only	RB
cord-022561-rv5j1201	2750	5	validated	validate	VBN
cord-022561-rv5j1201	2750	6	in	in	IN
cord-022561-rv5j1201	2750	7	dogs	dog	NNS
cord-022561-rv5j1201	2750	8	and	and	CC
cord-022561-rv5j1201	2750	9	horses	horse	NNS
cord-022561-rv5j1201	2750	10	Assay	Assay	NNP
cord-022561-rv5j1201	2750	11	detects	detect	VBZ
cord-022561-rv5j1201	2750	12	a	a	DT
cord-022561-rv5j1201	2750	13	specific	specific	JJ
cord-022561-rv5j1201	2750	14	type	type	NN
cord-022561-rv5j1201	2750	15	of	of	IN
cord-022561-rv5j1201	2750	16	FDP	FDP	NNP
cord-022561-rv5j1201	2750	17	resulting	result	VBG
cord-022561-rv5j1201	2750	18	from	from	IN
cord-022561-rv5j1201	2750	19	breakdown	breakdown	NN
cord-022561-rv5j1201	2750	20	of	of	IN
cord-022561-rv5j1201	2750	21	cross	cross	JJ
cord-022561-rv5j1201	2750	22	-	-	JJ
cord-022561-rv5j1201	2750	23	linked	link	VBN
cord-022561-rv5j1201	2750	24	fibrin	fibrin	NN
cord-022561-rv5j1201	2750	25	;	;	:
cord-022561-rv5j1201	2750	26	concentration	concentration	NN
cord-022561-rv5j1201	2750	27	of	of	IN
cord-022561-rv5j1201	2750	28	plasma	plasma	NN
cord-022561-rv5j1201	2750	29	D	d	NN
cord-022561-rv5j1201	2750	30	-	-	HYPH
cord-022561-rv5j1201	2750	31	dimer	dimer	NN
cord-022561-rv5j1201	2750	32	indicates	indicate	VBZ
cord-022561-rv5j1201	2750	33	the	the	DT
cord-022561-rv5j1201	2750	34	degree	degree	NN
cord-022561-rv5j1201	2750	35	of	of	IN
cord-022561-rv5j1201	2750	36	fibrinolysis	fibrinolysis	NN
cord-022561-rv5j1201	2750	37	;	;	:
cord-022561-rv5j1201	2750	38	often	often	RB
cord-022561-rv5j1201	2750	39	used	use	VBN
cord-022561-rv5j1201	2750	40	as	as	IN
cord-022561-rv5j1201	2750	41	part	part	NN
cord-022561-rv5j1201	2750	42	of	of	IN
cord-022561-rv5j1201	2750	43	a	a	DT
cord-022561-rv5j1201	2750	44	disseminated	disseminate	VBN
cord-022561-rv5j1201	2750	45	intravascular	intravascular	JJ
cord-022561-rv5j1201	2750	46	coagulation	coagulation	NN
cord-022561-rv5j1201	2750	47	panel	panel	NN
cord-022561-rv5j1201	2750	48	•	•	NNP
cord-022561-rv5j1201	2750	49	Required	require	VBN
cord-022561-rv5j1201	2750	50	sample	sample	NN
cord-022561-rv5j1201	2750	51	:	:	:
cord-022561-rv5j1201	2750	52	citrated	citrate	VBN
cord-022561-rv5j1201	2750	53	plasma	plasma	NN
cord-022561-rv5j1201	2750	54	.	.	.
cord-022561-rv5j1201	2751	1	•	•	NNP
cord-022561-rv5j1201	2751	2	Decreased	decrease	VBD
cord-022561-rv5j1201	2751	3	because	because	IN
cord-022561-rv5j1201	2751	4	of	of	IN
cord-022561-rv5j1201	2751	5	decreased	decrease	VBN
cord-022561-rv5j1201	2751	6	production	production	NN
cord-022561-rv5j1201	2751	7	(	(	-LRB-
cord-022561-rv5j1201	2751	8	liver	liver	NN
cord-022561-rv5j1201	2751	9	disease	disease	NN
cord-022561-rv5j1201	2751	10	)	)	-RRB-
cord-022561-rv5j1201	2751	11	,	,	,
cord-022561-rv5j1201	2751	12	loss	loss	NN
cord-022561-rv5j1201	2751	13	(	(	-LRB-
cord-022561-rv5j1201	2751	14	protein	protein	NN
cord-022561-rv5j1201	2751	15	-	-	HYPH
cord-022561-rv5j1201	2751	16	losing	lose	VBG
cord-022561-rv5j1201	2751	17	nephropathy	nephropathy	NN
cord-022561-rv5j1201	2751	18	or	or	CC
cord-022561-rv5j1201	2751	19	enteropathy	enteropathy	NNP
cord-022561-rv5j1201	2751	20	)	)	-RRB-
cord-022561-rv5j1201	2752	1	•	•	NNP
cord-022561-rv5j1201	2753	1	Specific	specific	JJ
cord-022561-rv5j1201	2753	2	factor	factor	NN
cord-022561-rv5j1201	2753	3	assays	assays	RB
cord-022561-rv5j1201	2754	1	•	•	NNP
cord-022561-rv5j1201	2755	1	Required	require	VBN
cord-022561-rv5j1201	2755	2	sample	sample	NN
cord-022561-rv5j1201	2755	3	:	:	:
cord-022561-rv5j1201	2755	4	citrated	citrate	VBN
cord-022561-rv5j1201	2755	5	plasma	plasma	NN
cord-022561-rv5j1201	2755	6	.	.	.
cord-022561-rv5j1201	2756	1	•	•	NNP
cord-022561-rv5j1201	2756	2	Performed	perform	VBN
cord-022561-rv5j1201	2756	3	at	at	IN
cord-022561-rv5j1201	2756	4	specialized	specialized	JJ
cord-022561-rv5j1201	2756	5	laboratories	laboratory	NNS
cord-022561-rv5j1201	2756	6	Intermediary	intermediary	JJ
cord-022561-rv5j1201	2756	7	spleen	spleen	NNS
cord-022561-rv5j1201	2756	8	microvasculature	microvasculature	NN
cord-022561-rv5j1201	2756	9	in	in	IN
cord-022561-rv5j1201	2756	10	Canis	Canis	NNP
cord-022561-rv5j1201	2756	11	familiaris	familiaris	NN
cord-022561-rv5j1201	2756	12	-	-	HYPH
cord-022561-rv5j1201	2756	13	morphological	morphological	JJ
cord-022561-rv5j1201	2756	14	evidence	evidence	NN
cord-022561-rv5j1201	2756	15	of	of	IN
cord-022561-rv5j1201	2756	16	a	a	DT
cord-022561-rv5j1201	2756	17	closed	closed	JJ
cord-022561-rv5j1201	2756	18	and	and	CC
cord-022561-rv5j1201	2756	19	open	open	JJ
cord-022561-rv5j1201	2756	20	type	type	NN
cord-022561-rv5j1201	2756	21	Molecular	molecular	JJ
cord-022561-rv5j1201	2756	22	methods	method	NNS
cord-022561-rv5j1201	2756	23	to	to	TO
cord-022561-rv5j1201	2756	24	distinguish	distinguish	VB
cord-022561-rv5j1201	2756	25	reactive	reactive	JJ
cord-022561-rv5j1201	2756	26	and	and	CC
cord-022561-rv5j1201	2756	27	neoplastic	neoplastic	JJ
cord-022561-rv5j1201	2756	28	lymphocyte	lymphocyte	NN
cord-022561-rv5j1201	2756	29	expansions	expansion	NNS
cord-022561-rv5j1201	2756	30	and	and	CC
cord-022561-rv5j1201	2756	31	their	-PRON-	PRP$
cord-022561-rv5j1201	2756	32	importance	importance	NN
cord-022561-rv5j1201	2756	33	in	in	IN
cord-022561-rv5j1201	2756	34	transitional	transitional	JJ
cord-022561-rv5j1201	2756	35	neoplastic	neoplastic	JJ
cord-022561-rv5j1201	2756	36	states	state	NNS
cord-022561-rv5j1201	2756	37	Characteristics	characteristic	NNS
cord-022561-rv5j1201	2756	38	,	,	,
cord-022561-rv5j1201	2756	39	diagnosis	diagnosis	NN
cord-022561-rv5j1201	2756	40	,	,	,
cord-022561-rv5j1201	2756	41	and	and	CC
cord-022561-rv5j1201	2756	42	treatment	treatment	NN
cord-022561-rv5j1201	2756	43	of	of	IN
cord-022561-rv5j1201	2756	44	inherited	inherit	VBN
cord-022561-rv5j1201	2756	45	platelet	platelet	NN
cord-022561-rv5j1201	2756	46	disorders	disorder	NNS
cord-022561-rv5j1201	2756	47	in	in	IN
cord-022561-rv5j1201	2756	48	mammals	mammal	NNS
cord-022561-rv5j1201	2756	49	Making	make	VBG
cord-022561-rv5j1201	2756	50	sense	sense	NN
cord-022561-rv5j1201	2756	51	of	of	IN
cord-022561-rv5j1201	2756	52	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2756	53	diagnostics	diagnostic	NNS
cord-022561-rv5j1201	2756	54	in	in	IN
cord-022561-rv5j1201	2756	55	small	small	JJ
cord-022561-rv5j1201	2756	56	animal	animal	NN
cord-022561-rv5j1201	2756	57	patients	patient	NNS
cord-022561-rv5j1201	2757	1	Canine	canine	JJ
cord-022561-rv5j1201	2757	2	granulocytic	granulocytic	JJ
cord-022561-rv5j1201	2757	3	anaplasmosis	anaplasmosis	NN
cord-022561-rv5j1201	2758	1	:	:	:
cord-022561-rv5j1201	2758	2	a	a	DT
cord-022561-rv5j1201	2758	3	review	review	NN
cord-022561-rv5j1201	2758	4	Lymphoid	lymphoid	JJ
cord-022561-rv5j1201	2758	5	tissues	tissue	NNS
cord-022561-rv5j1201	2758	6	and	and	CC
cord-022561-rv5j1201	2758	7	organs	organ	NNS
cord-022561-rv5j1201	2759	1	Lymph	lymph	NN
cord-022561-rv5j1201	2759	2	nodes	node	NNS
cord-022561-rv5j1201	2759	3	and	and	CC
cord-022561-rv5j1201	2759	4	thymus	thymus	NN
cord-022561-rv5j1201	2759	5	Diagnostic	diagnostic	JJ
cord-022561-rv5j1201	2759	6	cytology	cytology	NN
cord-022561-rv5j1201	2759	7	and	and	CC
cord-022561-rv5j1201	2759	8	hematology	hematology	NN
cord-022561-rv5j1201	2759	9	of	of	IN
cord-022561-rv5j1201	2759	10	the	the	DT
cord-022561-rv5j1201	2759	11	dog	dog	NN
cord-022561-rv5j1201	2759	12	and	and	CC
cord-022561-rv5j1201	2759	13	cat	cat	NN
cord-022561-rv5j1201	2760	1	Two	two	CD
cord-022561-rv5j1201	2760	2	hundred	hundred	CD
cord-022561-rv5j1201	2760	3	three	three	CD
cord-022561-rv5j1201	2760	4	cases	case	NNS
cord-022561-rv5j1201	2760	5	of	of	IN
cord-022561-rv5j1201	2760	6	equine	equine	JJ
cord-022561-rv5j1201	2760	7	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2760	8	classified	classify	VBN
cord-022561-rv5j1201	2760	9	according	accord	VBG
cord-022561-rv5j1201	2760	10	to	to	IN
cord-022561-rv5j1201	2760	11	the	the	DT
cord-022561-rv5j1201	2760	12	World	World	NNP
cord-022561-rv5j1201	2760	13	Health	Health	NNP
cord-022561-rv5j1201	2760	14	Organization	Organization	NNP
cord-022561-rv5j1201	2760	15	(	(	-LRB-
cord-022561-rv5j1201	2760	16	WHO	who	WP
cord-022561-rv5j1201	2760	17	)	)	-RRB-
cord-022561-rv5j1201	2760	18	classification	classification	NN
cord-022561-rv5j1201	2760	19	criteria	criteria	VBZ
cord-022561-rv5j1201	2760	20	Hepcidin	Hepcidin	NNP
cord-022561-rv5j1201	2760	21	:	:	:
cord-022561-rv5j1201	2760	22	a	a	DT
cord-022561-rv5j1201	2760	23	key	key	JJ
cord-022561-rv5j1201	2760	24	regulator	regulator	NN
cord-022561-rv5j1201	2760	25	of	of	IN
cord-022561-rv5j1201	2760	26	iron	iron	NN
cord-022561-rv5j1201	2760	27	metabolism	metabolism	NN
cord-022561-rv5j1201	2760	28	and	and	CC
cord-022561-rv5j1201	2760	29	mediator	mediator	NN
cord-022561-rv5j1201	2760	30	of	of	IN
cord-022561-rv5j1201	2760	31	anemia	anemia	NN
cord-022561-rv5j1201	2760	32	of	of	IN
cord-022561-rv5j1201	2760	33	inflammation	inflammation	NN
cord-022561-rv5j1201	2760	34	Changes	change	NNS
cord-022561-rv5j1201	2760	35	to	to	IN
cord-022561-rv5j1201	2760	36	bovine	bovine	JJ
cord-022561-rv5j1201	2760	37	hematology	hematology	NN
cord-022561-rv5j1201	2760	38	reference	reference	NN
cord-022561-rv5j1201	2760	39	intervals	interval	NNS
cord-022561-rv5j1201	2760	40	from	from	IN
cord-022561-rv5j1201	2760	41	1957	1957	CD
cord-022561-rv5j1201	2760	42	to	to	IN
cord-022561-rv5j1201	2760	43	Atlas	Atlas	NNP
cord-022561-rv5j1201	2760	44	of	of	IN
cord-022561-rv5j1201	2760	45	veterinary	veterinary	JJ
cord-022561-rv5j1201	2760	46	hematology	hematology	NN
cord-022561-rv5j1201	2760	47	:	:	:
cord-022561-rv5j1201	2760	48	blood	blood	NN
cord-022561-rv5j1201	2760	49	and	and	CC
cord-022561-rv5j1201	2760	50	bone	bone	NN
cord-022561-rv5j1201	2760	51	marrow	marrow	NN
cord-022561-rv5j1201	2760	52	of	of	IN
cord-022561-rv5j1201	2760	53	domestic	domestic	JJ
cord-022561-rv5j1201	2760	54	animals	animal	NNS
cord-022561-rv5j1201	2760	55	Pathogenesis	Pathogenesis	NNP
cord-022561-rv5j1201	2760	56	,	,	,
cord-022561-rv5j1201	2760	57	laboratory	laboratory	NN
cord-022561-rv5j1201	2760	58	diagnosis	diagnosis	NN
cord-022561-rv5j1201	2760	59	,	,	,
cord-022561-rv5j1201	2760	60	and	and	CC
cord-022561-rv5j1201	2760	61	clinical	clinical	JJ
cord-022561-rv5j1201	2760	62	implications	implication	NNS
cord-022561-rv5j1201	2760	63	of	of	IN
cord-022561-rv5j1201	2760	64	erythrocyte	erythrocyte	NN
cord-022561-rv5j1201	2760	65	enzyme	enzyme	NN
cord-022561-rv5j1201	2760	66	deficiencies	deficiency	NNS
cord-022561-rv5j1201	2760	67	in	in	IN
cord-022561-rv5j1201	2760	68	dogs	dog	NNS
cord-022561-rv5j1201	2760	69	,	,	,
cord-022561-rv5j1201	2760	70	cats	cat	NNS
cord-022561-rv5j1201	2760	71	,	,	,
cord-022561-rv5j1201	2760	72	and	and	CC
cord-022561-rv5j1201	2760	73	horses	horse	VBZ
cord-022561-rv5j1201	2760	74	Feline	feline	JJ
cord-022561-rv5j1201	2760	75	leukemia	leukemia	NN
cord-022561-rv5j1201	2760	76	virus	virus	NN
cord-022561-rv5j1201	2760	77	infection	infection	NN
cord-022561-rv5j1201	2760	78	and	and	CC
cord-022561-rv5j1201	2760	79	diseases	disease	NNS
cord-022561-rv5j1201	2760	80	Tumors	tumor	NNS
cord-022561-rv5j1201	2760	81	of	of	IN
cord-022561-rv5j1201	2760	82	the	the	DT
cord-022561-rv5j1201	2760	83	hemolymphatic	hemolymphatic	JJ
cord-022561-rv5j1201	2760	84	system	system	NN
cord-022561-rv5j1201	2761	1	Proposed	propose	VBN
cord-022561-rv5j1201	2761	2	criteria	criterion	NNS
cord-022561-rv5j1201	2761	3	for	for	IN
cord-022561-rv5j1201	2761	4	classification	classification	NN
cord-022561-rv5j1201	2761	5	of	of	IN
cord-022561-rv5j1201	2761	6	acute	acute	JJ
cord-022561-rv5j1201	2761	7	myeloid	myeloid	NN
cord-022561-rv5j1201	2761	8	leukemia	leukemia	NN
cord-022561-rv5j1201	2761	9	in	in	IN
cord-022561-rv5j1201	2761	10	dogs	dog	NNS
cord-022561-rv5j1201	2761	11	and	and	CC
cord-022561-rv5j1201	2761	12	cats	cat	NNS
cord-022561-rv5j1201	2761	13	Immunobiology	Immunobiology	NNP
cord-022561-rv5j1201	2761	14	:	:	:
cord-022561-rv5j1201	2761	15	the	the	DT
cord-022561-rv5j1201	2761	16	immune	immune	JJ
cord-022561-rv5j1201	2761	17	system	system	NN
cord-022561-rv5j1201	2761	18	in	in	IN
cord-022561-rv5j1201	2761	19	health	health	NN
cord-022561-rv5j1201	2761	20	and	and	CC
cord-022561-rv5j1201	2761	21	disease	disease	NN
cord-022561-rv5j1201	2761	22	Extramedullary	Extramedullary	NNP
cord-022561-rv5j1201	2761	23	hematopoiesis	hematopoiesis	NN
cord-022561-rv5j1201	2761	24	:	:	:
cord-022561-rv5j1201	2762	1	a	a	DT
cord-022561-rv5j1201	2762	2	new	new	JJ
cord-022561-rv5j1201	2762	3	look	look	NN
cord-022561-rv5j1201	2762	4	at	at	IN
cord-022561-rv5j1201	2762	5	the	the	DT
cord-022561-rv5j1201	2762	6	underlying	underlie	VBG
cord-022561-rv5j1201	2762	7	stem	stem	NN
cord-022561-rv5j1201	2762	8	cell	cell	NN
cord-022561-rv5j1201	2762	9	niche	niche	NN
cord-022561-rv5j1201	2762	10	,	,	,
cord-022561-rv5j1201	2762	11	theories	theory	NNS
cord-022561-rv5j1201	2762	12	of	of	IN
cord-022561-rv5j1201	2762	13	development	development	NN
cord-022561-rv5j1201	2762	14	,	,	,
cord-022561-rv5j1201	2762	15	and	and	CC
cord-022561-rv5j1201	2762	16	occurrence	occurrence	NN
cord-022561-rv5j1201	2762	17	in	in	IN
cord-022561-rv5j1201	2762	18	animals	animal	NNS
cord-022561-rv5j1201	2762	19	Lineage	lineage	NN
cord-022561-rv5j1201	2762	20	-	-	HYPH
cord-022561-rv5j1201	2762	21	specific	specific	JJ
cord-022561-rv5j1201	2762	22	hematopoietic	hematopoietic	JJ
cord-022561-rv5j1201	2762	23	growth	growth	NN
cord-022561-rv5j1201	2762	24	factors	factor	NNS
cord-022561-rv5j1201	2762	25	Hepatosplenic	Hepatosplenic	NNP
cord-022561-rv5j1201	2762	26	and	and	CC
cord-022561-rv5j1201	2762	27	hepatocytotropic	hepatocytotropic	NNP
cord-022561-rv5j1201	2762	28	T	t	NN
cord-022561-rv5j1201	2762	29	-	-	HYPH
cord-022561-rv5j1201	2762	30	cell	cell	NN
cord-022561-rv5j1201	2762	31	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2762	32	:	:	:
cord-022561-rv5j1201	2762	33	two	two	CD
cord-022561-rv5j1201	2762	34	distinct	distinct	JJ
cord-022561-rv5j1201	2762	35	types	type	NNS
cord-022561-rv5j1201	2762	36	of	of	IN
cord-022561-rv5j1201	2762	37	T	t	NN
cord-022561-rv5j1201	2762	38	-	-	HYPH
cord-022561-rv5j1201	2762	39	cell	cell	NN
cord-022561-rv5j1201	2762	40	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2762	41	in	in	IN
cord-022561-rv5j1201	2762	42	dogs	dog	NNS
cord-022561-rv5j1201	2762	43	Histology	histology	NN
cord-022561-rv5j1201	2762	44	and	and	CC
cord-022561-rv5j1201	2762	45	cell	cell	NN
cord-022561-rv5j1201	2762	46	biology	biology	NN
cord-022561-rv5j1201	2762	47	:	:	:
cord-022561-rv5j1201	2762	48	an	an	DT
cord-022561-rv5j1201	2762	49	introduction	introduction	NN
cord-022561-rv5j1201	2762	50	to	to	IN
cord-022561-rv5j1201	2762	51	pathology	pathology	NN
cord-022561-rv5j1201	2762	52	Lymphoid	lymphoid	JJ
cord-022561-rv5j1201	2762	53	neoplasms	neoplasm	NNS
cord-022561-rv5j1201	2762	54	in	in	IN
cord-022561-rv5j1201	2762	55	swine	swine	NN
cord-022561-rv5j1201	2762	56	JC	JC	NNP
cord-022561-rv5j1201	2762	57	:	:	:
cord-022561-rv5j1201	2762	58	Robbins	Robbins	NNP
cord-022561-rv5j1201	2762	59	&	&	CC
cord-022561-rv5j1201	2762	60	Cotran	Cotran	NNP
cord-022561-rv5j1201	2762	61	pathologic	pathologic	JJ
cord-022561-rv5j1201	2762	62	basis	basis	NN
cord-022561-rv5j1201	2762	63	of	of	IN
cord-022561-rv5j1201	2762	64	disease	disease	NN
cord-022561-rv5j1201	2763	1	The	the	DT
cord-022561-rv5j1201	2763	2	spleen	spleen	NN
cord-022561-rv5j1201	2763	3	Ehrlichiosis	Ehrlichiosis	NNP
cord-022561-rv5j1201	2763	4	and	and	CC
cord-022561-rv5j1201	2763	5	related	relate	VBN
cord-022561-rv5j1201	2763	6	infections	infection	NNS
cord-022561-rv5j1201	2763	7	Hemotropic	Hemotropic	NNP
cord-022561-rv5j1201	2763	8	mycoplasmas	mycoplasmas	NNP
cord-022561-rv5j1201	2763	9	(	(	-LRB-
cord-022561-rv5j1201	2763	10	hemoplasmas	hemoplasmas	NNP
cord-022561-rv5j1201	2763	11	)	)	-RRB-
cord-022561-rv5j1201	2763	12	:	:	:
cord-022561-rv5j1201	2763	13	a	a	DT
cord-022561-rv5j1201	2763	14	review	review	NN
cord-022561-rv5j1201	2763	15	and	and	CC
cord-022561-rv5j1201	2763	16	new	new	JJ
cord-022561-rv5j1201	2763	17	insights	insight	NNS
cord-022561-rv5j1201	2763	18	into	into	IN
cord-022561-rv5j1201	2763	19	pathogenic	pathogenic	JJ
cord-022561-rv5j1201	2763	20	potential	potential	JJ
cord-022561-rv5j1201	2763	21	Clinical	clinical	JJ
cord-022561-rv5j1201	2763	22	,	,	,
cord-022561-rv5j1201	2763	23	laboratory	laboratory	NN
cord-022561-rv5j1201	2763	24	,	,	,
cord-022561-rv5j1201	2763	25	and	and	CC
cord-022561-rv5j1201	2763	26	histopathologic	histopathologic	NNP
cord-022561-rv5j1201	2763	27	features	feature	NNS
cord-022561-rv5j1201	2763	28	of	of	IN
cord-022561-rv5j1201	2763	29	equine	equine	JJ
cord-022561-rv5j1201	2763	30	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2763	31	Classification	classification	NN
cord-022561-rv5j1201	2763	32	and	and	CC
cord-022561-rv5j1201	2763	33	clinical	clinical	JJ
cord-022561-rv5j1201	2763	34	features	feature	NNS
cord-022561-rv5j1201	2763	35	in	in	IN
cord-022561-rv5j1201	2763	36	88	88	CD
cord-022561-rv5j1201	2763	37	cases	case	NNS
cord-022561-rv5j1201	2763	38	of	of	IN
cord-022561-rv5j1201	2763	39	equine	equine	JJ
cord-022561-rv5j1201	2763	40	cutaneous	cutaneous	JJ
cord-022561-rv5j1201	2763	41	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2763	42	Histologic	Histologic	NNP
cord-022561-rv5j1201	2763	43	and	and	CC
cord-022561-rv5j1201	2763	44	immunohistochemical	immunohistochemical	JJ
cord-022561-rv5j1201	2763	45	review	review	NN
cord-022561-rv5j1201	2763	46	of	of	IN
cord-022561-rv5j1201	2763	47	splenic	splenic	JJ
cord-022561-rv5j1201	2763	48	fibrohistiocytic	fibrohistiocytic	JJ
cord-022561-rv5j1201	2763	49	nodules	nodule	NNS
cord-022561-rv5j1201	2763	50	in	in	IN
cord-022561-rv5j1201	2763	51	dogs	dog	NNS
cord-022561-rv5j1201	2763	52	Feline	feline	JJ
cord-022561-rv5j1201	2763	53	gastrointestinal	gastrointestinal	JJ
cord-022561-rv5j1201	2763	54	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2763	55	:	:	:
cord-022561-rv5j1201	2763	56	mucosal	mucosal	JJ
cord-022561-rv5j1201	2763	57	architecture	architecture	NN
cord-022561-rv5j1201	2763	58	,	,	,
cord-022561-rv5j1201	2763	59	immunophenotype	immunophenotype	NN
cord-022561-rv5j1201	2763	60	,	,	,
cord-022561-rv5j1201	2763	61	and	and	CC
cord-022561-rv5j1201	2763	62	molecular	molecular	JJ
cord-022561-rv5j1201	2763	63	clonality	clonality	NN
cord-022561-rv5j1201	2763	64	Current	current	JJ
cord-022561-rv5j1201	2763	65	state	state	NN
cord-022561-rv5j1201	2763	66	of	of	IN
cord-022561-rv5j1201	2763	67	knowledge	knowledge	NN
cord-022561-rv5j1201	2763	68	on	on	IN
cord-022561-rv5j1201	2763	69	porcine	porcine	JJ
cord-022561-rv5j1201	2763	70	circovirus	circovirus	JJ
cord-022561-rv5j1201	2763	71	type	type	NN
cord-022561-rv5j1201	2763	72	2-associated	2-associated	CD
cord-022561-rv5j1201	2763	73	lesions	lesion	NNS
cord-022561-rv5j1201	2763	74	Molecular	molecular	JJ
cord-022561-rv5j1201	2763	75	pathology	pathology	NN
cord-022561-rv5j1201	2763	76	of	of	IN
cord-022561-rv5j1201	2763	77	severe	severe	JJ
cord-022561-rv5j1201	2763	78	combined	combine	VBN
cord-022561-rv5j1201	2763	79	immunodeficiency	immunodeficiency	NN
cord-022561-rv5j1201	2763	80	in	in	IN
cord-022561-rv5j1201	2763	81	mice	mouse	NNS
cord-022561-rv5j1201	2763	82	,	,	,
cord-022561-rv5j1201	2763	83	horses	horse	NNS
cord-022561-rv5j1201	2763	84	,	,	,
cord-022561-rv5j1201	2763	85	and	and	CC
cord-022561-rv5j1201	2763	86	dogs	dog	NNS
cord-022561-rv5j1201	2764	1	Hematologic	Hematologic	NNP
cord-022561-rv5j1201	2764	2	abnormalities	abnormality	NNS
cord-022561-rv5j1201	2764	3	associated	associate	VBN
cord-022561-rv5j1201	2764	4	with	with	IN
cord-022561-rv5j1201	2764	5	retroviral	retroviral	JJ
cord-022561-rv5j1201	2764	6	infections	infection	NNS
cord-022561-rv5j1201	2764	7	in	in	IN
cord-022561-rv5j1201	2764	8	the	the	DT
cord-022561-rv5j1201	2764	9	cat	cat	NN
cord-022561-rv5j1201	2764	10	Pathology	Pathology	NNP
cord-022561-rv5j1201	2764	11	of	of	IN
cord-022561-rv5j1201	2764	12	the	the	DT
cord-022561-rv5j1201	2764	13	pig	pig	NN
cord-022561-rv5j1201	2764	14	:	:	:
cord-022561-rv5j1201	2764	15	a	a	DT
cord-022561-rv5j1201	2764	16	diagnostic	diagnostic	JJ
cord-022561-rv5j1201	2764	17	guide	guide	NN
cord-022561-rv5j1201	2764	18	Pathologic	pathologic	JJ
cord-022561-rv5j1201	2764	19	and	and	CC
cord-022561-rv5j1201	2764	20	prognostic	prognostic	JJ
cord-022561-rv5j1201	2764	21	characteristics	characteristic	NNS
cord-022561-rv5j1201	2764	22	of	of	IN
cord-022561-rv5j1201	2764	23	splenomegaly	splenomegaly	NN
cord-022561-rv5j1201	2764	24	in	in	IN
cord-022561-rv5j1201	2764	25	dogs	dog	NNS
cord-022561-rv5j1201	2764	26	due	due	JJ
cord-022561-rv5j1201	2764	27	to	to	IN
cord-022561-rv5j1201	2764	28	fibrohistiocytic	fibrohistiocytic	JJ
cord-022561-rv5j1201	2764	29	nodules	nodule	NNS
cord-022561-rv5j1201	2764	30	:	:	:
cord-022561-rv5j1201	2764	31	98	98	CD
cord-022561-rv5j1201	2764	32	cases	case	NNS
cord-022561-rv5j1201	2765	1	Splenic	Splenic	NNP
cord-022561-rv5j1201	2765	2	myeloid	myeloid	NN
cord-022561-rv5j1201	2765	3	metaplasia	metaplasia	NN
cord-022561-rv5j1201	2765	4	,	,	,
cord-022561-rv5j1201	2765	5	histiocytosis	histiocytosis	NN
cord-022561-rv5j1201	2765	6	,	,	,
cord-022561-rv5j1201	2765	7	and	and	CC
cord-022561-rv5j1201	2765	8	hypersplenism	hypersplenism	NN
cord-022561-rv5j1201	2765	9	in	in	IN
cord-022561-rv5j1201	2765	10	the	the	DT
cord-022561-rv5j1201	2765	11	dog	dog	NN
cord-022561-rv5j1201	2765	12	(	(	-LRB-
cord-022561-rv5j1201	2765	13	65	65	CD
cord-022561-rv5j1201	2765	14	cases	case	NNS
cord-022561-rv5j1201	2765	15	)	)	-RRB-
cord-022561-rv5j1201	2766	1	Fundamentals	fundamental	NNS
cord-022561-rv5j1201	2766	2	of	of	IN
cord-022561-rv5j1201	2766	3	veterinary	veterinary	JJ
cord-022561-rv5j1201	2766	4	clinical	clinical	JJ
cord-022561-rv5j1201	2766	5	pathology	pathology	NN
cord-022561-rv5j1201	2766	6	Feline	feline	JJ
cord-022561-rv5j1201	2766	7	parvovirus	parvovirus	NN
cord-022561-rv5j1201	2766	8	infection	infection	NN
cord-022561-rv5j1201	2766	9	and	and	CC
cord-022561-rv5j1201	2766	10	associated	associated	JJ
cord-022561-rv5j1201	2766	11	diseases	disease	NNS
cord-022561-rv5j1201	2767	1	Novel	novel	JJ
cord-022561-rv5j1201	2767	2	gammaherpesviruses	gammaherpesviruse	NNS
cord-022561-rv5j1201	2767	3	in	in	IN
cord-022561-rv5j1201	2767	4	North	north	JJ
cord-022561-rv5j1201	2767	5	American	american	JJ
cord-022561-rv5j1201	2767	6	domestic	domestic	JJ
cord-022561-rv5j1201	2767	7	cats	cat	NNS
cord-022561-rv5j1201	2767	8	,	,	,
cord-022561-rv5j1201	2767	9	bobcats	bobcat	NNS
cord-022561-rv5j1201	2767	10	,	,	,
cord-022561-rv5j1201	2767	11	and	and	CC
cord-022561-rv5j1201	2767	12	pumas	puma	NNS
cord-022561-rv5j1201	2767	13	:	:	:
cord-022561-rv5j1201	2767	14	identification	identification	NN
cord-022561-rv5j1201	2767	15	,	,	,
cord-022561-rv5j1201	2767	16	prevalence	prevalence	NN
cord-022561-rv5j1201	2767	17	,	,	,
cord-022561-rv5j1201	2767	18	and	and	CC
cord-022561-rv5j1201	2767	19	risk	risk	NN
cord-022561-rv5j1201	2767	20	factors	factor	NNS
cord-022561-rv5j1201	2768	1	Palmer	Palmer	NNP
cord-022561-rv5j1201	2768	2	's	's	POS
cord-022561-rv5j1201	2768	3	pathology	pathology	NN
cord-022561-rv5j1201	2768	4	of	of	IN
cord-022561-rv5j1201	2768	5	domestic	domestic	JJ
cord-022561-rv5j1201	2768	6	animals	animal	NNS
cord-022561-rv5j1201	2768	7	Veterinary	veterinary	JJ
cord-022561-rv5j1201	2768	8	comparative	comparative	JJ
cord-022561-rv5j1201	2768	9	hematopathology	hematopathology	NN
cord-022561-rv5j1201	2768	10	Histologic	Histologic	NNP
cord-022561-rv5j1201	2768	11	classification	classification	NN
cord-022561-rv5j1201	2768	12	of	of	IN
cord-022561-rv5j1201	2768	13	hematopoietic	hematopoietic	JJ
cord-022561-rv5j1201	2768	14	tumors	tumor	NNS
cord-022561-rv5j1201	2768	15	of	of	IN
cord-022561-rv5j1201	2768	16	domestic	domestic	JJ
cord-022561-rv5j1201	2768	17	animals	animal	NNS
cord-022561-rv5j1201	2768	18	.	.	.
cord-022561-rv5j1201	2769	1	In	in	IN
cord-022561-rv5j1201	2769	2	World	World	NNP
cord-022561-rv5j1201	2769	3	Health	Health	NNP
cord-022561-rv5j1201	2769	4	Organization	Organization	NNP
cord-022561-rv5j1201	2769	5	international	international	JJ
cord-022561-rv5j1201	2769	6	histological	histological	JJ
cord-022561-rv5j1201	2769	7	classification	classification	NN
cord-022561-rv5j1201	2769	8	of	of	IN
cord-022561-rv5j1201	2769	9	tumors	tumor	NNS
cord-022561-rv5j1201	2769	10	in	in	IN
cord-022561-rv5j1201	2769	11	domestic	domestic	JJ
cord-022561-rv5j1201	2769	12	animals	animal	NNS
cord-022561-rv5j1201	2769	13	,	,	,
cord-022561-rv5j1201	2769	14	second	second	JJ
cord-022561-rv5j1201	2769	15	series	series	NN
cord-022561-rv5j1201	2769	16	Canine	canine	JJ
cord-022561-rv5j1201	2769	17	lymphomas	lymphoma	NNS
cord-022561-rv5j1201	2769	18	:	:	:
cord-022561-rv5j1201	2769	19	association	association	NNP
cord-022561-rv5j1201	2769	20	of	of	IN
cord-022561-rv5j1201	2769	21	classification	classification	NN
cord-022561-rv5j1201	2769	22	type	type	NN
cord-022561-rv5j1201	2769	23	,	,	,
cord-022561-rv5j1201	2769	24	disease	disease	NN
cord-022561-rv5j1201	2769	25	stage	stage	NN
cord-022561-rv5j1201	2769	26	,	,	,
cord-022561-rv5j1201	2769	27	tumor	tumor	NN
cord-022561-rv5j1201	2769	28	subtype	subtype	NN
cord-022561-rv5j1201	2769	29	,	,	,
cord-022561-rv5j1201	2769	30	mitotic	mitotic	JJ
cord-022561-rv5j1201	2769	31	rate	rate	NN
cord-022561-rv5j1201	2769	32	,	,	,
cord-022561-rv5j1201	2769	33	and	and	CC
cord-022561-rv5j1201	2769	34	treatment	treatment	NN
cord-022561-rv5j1201	2769	35	with	with	IN
cord-022561-rv5j1201	2769	36	survival	survival	NN
cord-022561-rv5j1201	2769	37	Classification	classification	NN
cord-022561-rv5j1201	2769	38	of	of	IN
cord-022561-rv5j1201	2769	39	canine	canine	JJ
cord-022561-rv5j1201	2769	40	malignant	malignant	JJ
cord-022561-rv5j1201	2769	41	lymphomas	lymphoma	NNS
cord-022561-rv5j1201	2769	42	according	accord	VBG
cord-022561-rv5j1201	2769	43	to	to	IN
cord-022561-rv5j1201	2769	44	the	the	DT
cord-022561-rv5j1201	2769	45	World	World	NNP
cord-022561-rv5j1201	2769	46	Health	Health	NNP
cord-022561-rv5j1201	2769	47	Organization	Organization	NNP
cord-022561-rv5j1201	2769	48	criteria	criteria	VBZ
cord-022561-rv5j1201	2769	49	Canine	canine	JJ
cord-022561-rv5j1201	2769	50	indolent	indolent	JJ
cord-022561-rv5j1201	2769	51	nodular	nodular	JJ
cord-022561-rv5j1201	2769	52	lymphoma	lymphoma	NN
cord-022561-rv5j1201	2770	1	The	the	DT
cord-022561-rv5j1201	2770	2	2008	2008	CD
cord-022561-rv5j1201	2770	3	revision	revision	NN
cord-022561-rv5j1201	2770	4	of	of	IN
cord-022561-rv5j1201	2770	5	the	the	DT
cord-022561-rv5j1201	2770	6	World	World	NNP
cord-022561-rv5j1201	2770	7	Health	Health	NNP
cord-022561-rv5j1201	2770	8	Organization	Organization	NNP
cord-022561-rv5j1201	2770	9	(	(	-LRB-
cord-022561-rv5j1201	2770	10	WHO	who	WP
cord-022561-rv5j1201	2770	11	)	)	-RRB-
cord-022561-rv5j1201	2770	12	classification	classification	NN
cord-022561-rv5j1201	2770	13	of	of	IN
cord-022561-rv5j1201	2770	14	myeloid	myeloid	JJ
cord-022561-rv5j1201	2770	15	neoplasms	neoplasm	NNS
cord-022561-rv5j1201	2770	16	and	and	CC
cord-022561-rv5j1201	2770	17	acute	acute	JJ
cord-022561-rv5j1201	2770	18	leukemia	leukemia	NN
cord-022561-rv5j1201	2770	19	:	:	:
cord-022561-rv5j1201	2770	20	rationale	rationale	NN
cord-022561-rv5j1201	2770	21	and	and	CC
cord-022561-rv5j1201	2770	22	important	important	JJ
cord-022561-rv5j1201	2770	23	changes	change	NNS
cord-022561-rv5j1201	2770	24	The	the	DT
cord-022561-rv5j1201	2770	25	Coombs	Coombs	NNP
cord-022561-rv5j1201	2770	26	'	'	POS
cord-022561-rv5j1201	2770	27	test	test	NN
cord-022561-rv5j1201	2770	28	in	in	IN
cord-022561-rv5j1201	2770	29	veterinary	veterinary	JJ
cord-022561-rv5j1201	2770	30	medicine	medicine	NN
cord-022561-rv5j1201	2770	31	:	:	:
cord-022561-rv5j1201	2770	32	past	past	NN
cord-022561-rv5j1201	2770	33	,	,	,
cord-022561-rv5j1201	2770	34	present	present	JJ
cord-022561-rv5j1201	2770	35	,	,	,
cord-022561-rv5j1201	2770	36	future	future	JJ
cord-022561-rv5j1201	2770	37	A	a	DT
cord-022561-rv5j1201	2770	38	retrospective	retrospective	JJ
cord-022561-rv5j1201	2770	39	study	study	NN
cord-022561-rv5j1201	2770	40	of	of	IN
cord-022561-rv5j1201	2770	41	the	the	DT
cord-022561-rv5j1201	2770	42	incidence	incidence	NN
cord-022561-rv5j1201	2770	43	and	and	CC
cord-022561-rv5j1201	2770	44	the	the	DT
cord-022561-rv5j1201	2770	45	classification	classification	NN
cord-022561-rv5j1201	2770	46	of	of	IN
cord-022561-rv5j1201	2770	47	bone	bone	NN
cord-022561-rv5j1201	2770	48	marrow	marrow	NN
cord-022561-rv5j1201	2770	49	disorders	disorder	NNS
cord-022561-rv5j1201	2770	50	in	in	IN
cord-022561-rv5j1201	2770	51	the	the	DT
cord-022561-rv5j1201	2770	52	dog	dog	NN
cord-022561-rv5j1201	2770	53	at	at	IN
cord-022561-rv5j1201	2770	54	a	a	DT
cord-022561-rv5j1201	2770	55	veterinary	veterinary	JJ
cord-022561-rv5j1201	2770	56	teaching	teaching	NN
cord-022561-rv5j1201	2770	57	hospital	hospital	NN
cord-022561-rv5j1201	2770	58	(	(	-LRB-
cord-022561-rv5j1201	2770	59	1996	1996	CD
cord-022561-rv5j1201	2770	60	-	-	SYM
cord-022561-rv5j1201	2770	61	2004	2004	CD
cord-022561-rv5j1201	2770	62	)	)	-RRB-
cord-022561-rv5j1201	2771	1	Schalm	Schalm	NNP
cord-022561-rv5j1201	2771	2	's	's	POS
cord-022561-rv5j1201	2771	3	veterinary	veterinary	JJ
cord-022561-rv5j1201	2771	4	hematology	hematology	NN
cord-022561-rv5j1201	2771	5	Chronic	Chronic	NNP
cord-022561-rv5j1201	2771	6	lymphocytic	lymphocytic	JJ
cord-022561-rv5j1201	2771	7	leukemia	leukemia	NN
cord-022561-rv5j1201	2771	8	in	in	IN
cord-022561-rv5j1201	2771	9	dogs	dog	NNS
cord-022561-rv5j1201	2771	10	and	and	CC
cord-022561-rv5j1201	2771	11	cats	cat	NNS
cord-022561-rv5j1201	2771	12	:	:	:
cord-022561-rv5j1201	2772	1	the	the	DT
cord-022561-rv5j1201	2772	2	veterinary	veterinary	JJ
cord-022561-rv5j1201	2772	3	perspective	perspective	NN
cord-022561-rv5j1201	2772	4	Grossly	grossly	RB
cord-022561-rv5j1201	2772	5	,	,	,
cord-022561-rv5j1201	2772	6	incompletely	incompletely	RB
cord-022561-rv5j1201	2772	7	contracted	contract	VBN
cord-022561-rv5j1201	2772	8	areas	area	NNS
cord-022561-rv5j1201	2772	9	are	be	VBP
cord-022561-rv5j1201	2772	10	characterized	characterize	VBN
cord-022561-rv5j1201	2772	11	by	by	IN
cord-022561-rv5j1201	2772	12	multiple	multiple	JJ
cord-022561-rv5j1201	2772	13	,	,	,
cord-022561-rv5j1201	2772	14	variably	variably	RB
cord-022561-rv5j1201	2772	15	sized	sized	JJ
cord-022561-rv5j1201	2772	16	and	and	CC
cord-022561-rv5j1201	2772	17	irregularly	irregularly	RB
cord-022561-rv5j1201	2772	18	shaped	shaped	JJ
cord-022561-rv5j1201	2772	19	,	,	,
cord-022561-rv5j1201	2772	20	dark	dark	JJ
cord-022561-rv5j1201	2772	21	red	red	NN
cord-022561-rv5j1201	2772	22	to	to	IN
cord-022561-rv5j1201	2772	23	black	black	JJ
cord-022561-rv5j1201	2772	24	,	,	,
cord-022561-rv5j1201	2772	25	raised	raise	VBN
cord-022561-rv5j1201	2772	26	,	,	,
cord-022561-rv5j1201	2772	27	soft	soft	JJ
cord-022561-rv5j1201	2772	28	,	,	,
cord-022561-rv5j1201	2772	29	blood	blood	NN
cord-022561-rv5j1201	2772	30	-	-	HYPH
cord-022561-rv5j1201	2772	31	filled	fill	VBN
cord-022561-rv5j1201	2772	32	"	"	``
cord-022561-rv5j1201	2772	33	nodules	nodule	NNS
cord-022561-rv5j1201	2772	34	.	.	.
cord-022561-rv5j1201	2772	35	"	"	''
cord-022561-rv5j1201	2773	1	These	these	DT
cord-022561-rv5j1201	2773	2	areas	area	NNS
cord-022561-rv5j1201	2773	3	are	be	VBP
cord-022561-rv5j1201	2773	4	usually	usually	RB
cord-022561-rv5j1201	2773	5	at	at	IN
cord-022561-rv5j1201	2773	6	the	the	DT
cord-022561-rv5j1201	2773	7	margins	margin	NNS
cord-022561-rv5j1201	2773	8	of	of	IN
cord-022561-rv5j1201	2773	9	the	the	DT
cord-022561-rv5j1201	2773	10	spleen	spleen	NN
cord-022561-rv5j1201	2773	11	,	,	,
cord-022561-rv5j1201	2773	12	and	and	CC
cord-022561-rv5j1201	2773	13	the	the	DT
cord-022561-rv5j1201	2773	14	intervening	intervene	VBG
cord-022561-rv5j1201	2773	15	tissues	tissue	NNS
cord-022561-rv5j1201	2773	16	are	be	VBP
cord-022561-rv5j1201	2773	17	depressed	depressed	JJ
cord-022561-rv5j1201	2773	18	and	and	CC
cord-022561-rv5j1201	2773	19	pink	pink	JJ
cord-022561-rv5j1201	2773	20	-	-	HYPH
cord-022561-rv5j1201	2773	21	red	red	JJ
cord-022561-rv5j1201	2773	22	,	,	,
cord-022561-rv5j1201	2773	23	corresponding	correspond	VBG
cord-022561-rv5j1201	2773	24	to	to	IN
cord-022561-rv5j1201	2773	25	the	the	DT
cord-022561-rv5j1201	2773	26	contracted	contract	VBN
cord-022561-rv5j1201	2773	27	portions	portion	NNS
cord-022561-rv5j1201	2773	28	of	of	IN
cord-022561-rv5j1201	2773	29	red	red	JJ
cord-022561-rv5j1201	2773	30	pulp	pulp	NN
cord-022561-rv5j1201	2773	31	devoid	devoid	NN
cord-022561-rv5j1201	2773	32	of	of	IN
cord-022561-rv5j1201	2773	33	blood	blood	NN
cord-022561-rv5j1201	2773	34	.	.	.
cord-022561-rv5j1201	2774	1	Incompletely	incompletely	RB
cord-022561-rv5j1201	2774	2	contracted	contract	VBN
cord-022561-rv5j1201	2774	3	areas	area	NNS
cord-022561-rv5j1201	2774	4	may	may	MD
cord-022561-rv5j1201	2774	5	be	be	VB
cord-022561-rv5j1201	2774	6	confused	confuse	VBN
cord-022561-rv5j1201	2774	7	with	with	IN
cord-022561-rv5j1201	2774	8	acute	acute	JJ
cord-022561-rv5j1201	2774	9	splenic	splenic	JJ
cord-022561-rv5j1201	2774	10	infarcts	infarct	NNS
cord-022561-rv5j1201	2774	11	or	or	CC
cord-022561-rv5j1201	2774	12	hematomas	hematoma	NNS
cord-022561-rv5j1201	2774	13	on	on	IN
cord-022561-rv5j1201	2774	14	gross	gross	JJ
cord-022561-rv5j1201	2774	15	examination	examination	NN
cord-022561-rv5j1201	2774	16	.	.	.
cord-022561-rv5j1201	2775	1	Acute	Acute	NNP
cord-022561-rv5j1201	2775	2	Splenic	Splenic	NNP
cord-022561-rv5j1201	2775	3	Infarcts	infarct	NNS
cord-022561-rv5j1201	2775	4	.	.	.
cord-022561-rv5j1201	2776	1	Splenic	Splenic	NNP
cord-022561-rv5j1201	2776	2	infarcts	infarct	NNS
cord-022561-rv5j1201	2776	3	are	be	VBP
cord-022561-rv5j1201	2776	4	wedge	wedge	NN
cord-022561-rv5j1201	2776	5	-	-	HYPH
cord-022561-rv5j1201	2776	6	shaped	shape	VBN
cord-022561-rv5j1201	2776	7	or	or	CC
cord-022561-rv5j1201	2776	8	triangular	triangular	JJ
cord-022561-rv5j1201	2776	9	hemorrhagic	hemorrhagic	JJ
cord-022561-rv5j1201	2776	10	lesions	lesion	NNS
cord-022561-rv5j1201	2776	11	that	that	WDT
cord-022561-rv5j1201	2776	12	occur	occur	VBP
cord-022561-rv5j1201	2776	13	primarily	primarily	RB
cord-022561-rv5j1201	2776	14	at	at	IN
cord-022561-rv5j1201	2776	15	the	the	DT
cord-022561-rv5j1201	2776	16	margins	margin	NNS
cord-022561-rv5j1201	2776	17	of	of	IN
cord-022561-rv5j1201	2776	18	the	the	DT
cord-022561-rv5j1201	2776	19	spleen	spleen	NN
cord-022561-rv5j1201	2776	20	.	.	.
cord-022561-rv5j1201	2777	1	In	in	IN
cord-022561-rv5j1201	2777	2	dogs	dog	NNS
cord-022561-rv5j1201	2777	3	,	,	,
cord-022561-rv5j1201	2777	4	splenic	splenic	JJ
cord-022561-rv5j1201	2777	5	infarcts	infarct	NNS
cord-022561-rv5j1201	2777	6	most	most	RBS
cord-022561-rv5j1201	2777	7	often	often	RB
cord-022561-rv5j1201	2777	8	occur	occur	VBP
cord-022561-rv5j1201	2777	9	with	with	IN
cord-022561-rv5j1201	2777	10	hypercoagulable	hypercoagulable	JJ
cord-022561-rv5j1201	2777	11	states	state	NNS
cord-022561-rv5j1201	2777	12	(	(	-LRB-
cord-022561-rv5j1201	2777	13	e.g.	e.g.	RB
cord-022561-rv5j1201	2777	14	,	,	,
cord-022561-rv5j1201	2777	15	liver	liver	NN
cord-022561-rv5j1201	2777	16	disease	disease	NN
cord-022561-rv5j1201	2777	17	,	,	,
cord-022561-rv5j1201	2777	18	renal	renal	JJ
cord-022561-rv5j1201	2777	19	disease	disease	NN
cord-022561-rv5j1201	2777	20	,	,	,
cord-022561-rv5j1201	2777	21	Cushing	Cushing	NNP
cord-022561-rv5j1201	2777	22	's	's	POS
cord-022561-rv5j1201	2777	23	disease	disease	NN
cord-022561-rv5j1201	2777	24	)	)	-RRB-
cord-022561-rv5j1201	2777	25	,	,	,
cord-022561-rv5j1201	2777	26	neoplasia	neoplasia	NN
cord-022561-rv5j1201	2777	27	,	,	,
cord-022561-rv5j1201	2777	28	and	and	CC
cord-022561-rv5j1201	2777	29	cardiovascular	cardiovascular	JJ
cord-022561-rv5j1201	2777	30	disease	disease	NN
cord-022561-rv5j1201	2777	31	.	.	.
cord-022561-rv5j1201	2778	1	Splenic	splenic	JJ
cord-022561-rv5j1201	2778	2	vein	vein	NN
cord-022561-rv5j1201	2778	3	thrombi	thrombi	NNP
cord-022561-rv5j1201	2778	4	may	may	MD
cord-022561-rv5j1201	2778	5	occur	occur	VB
cord-022561-rv5j1201	2778	6	in	in	IN
cord-022561-rv5j1201	2778	7	association	association	NN
cord-022561-rv5j1201	2778	8	with	with	IN
cord-022561-rv5j1201	2778	9	traumatic	traumatic	JJ
cord-022561-rv5j1201	2778	10	reticulitis	reticulitis	NN
cord-022561-rv5j1201	2778	11	,	,	,
cord-022561-rv5j1201	2778	12	splenic	splenic	JJ
cord-022561-rv5j1201	2778	13	abscesses	abscess	NNS
cord-022561-rv5j1201	2778	14	,	,	,
cord-022561-rv5j1201	2778	15	portal	portal	JJ
cord-022561-rv5j1201	2778	16	vein	vein	NN
cord-022561-rv5j1201	2778	17	thrombosis	thrombosis	NN
cord-022561-rv5j1201	2778	18	,	,	,
cord-022561-rv5j1201	2778	19	and	and	CC
cord-022561-rv5j1201	2778	20	arterial	arterial	JJ
cord-022561-rv5j1201	2778	21	thrombosis	thrombosis	NN
cord-022561-rv5j1201	2778	22	in	in	IN
cord-022561-rv5j1201	2778	23	bovine	bovine	JJ
cord-022561-rv5j1201	2778	24	theileriosis	theileriosis	NN
cord-022561-rv5j1201	2778	25	in	in	IN
cord-022561-rv5j1201	2778	26	cattle	cattle	NNS
cord-022561-rv5j1201	2778	27	.	.	.
cord-022561-rv5j1201	2779	1	Valvular	Valvular	NNP
cord-022561-rv5j1201	2779	2	endocarditis	endocarditis	NN
cord-022561-rv5j1201	2779	3	may	may	MD
cord-022561-rv5j1201	2779	4	also	also	RB
cord-022561-rv5j1201	2779	5	lead	lead	VB
cord-022561-rv5j1201	2779	6	to	to	IN
cord-022561-rv5j1201	2779	7	multiorgan	multiorgan	NNP
cord-022561-rv5j1201	2779	8	infarcts	infarct	NNS
cord-022561-rv5j1201	2779	9	,	,	,
cord-022561-rv5j1201	2779	10	including	include	VBG
cord-022561-rv5j1201	2779	11	the	the	DT
cord-022561-rv5j1201	2779	12	spleen	spleen	NN
cord-022561-rv5j1201	2779	13	.	.	.
cord-022561-rv5j1201	2780	1	Splenic	Splenic	NNP
cord-022561-rv5j1201	2780	2	infarcts	infarct	NNS
cord-022561-rv5j1201	2780	3	are	be	VBP
cord-022561-rv5j1201	2780	4	common	common	JJ
cord-022561-rv5j1201	2780	5	in	in	IN
cord-022561-rv5j1201	2780	6	pigs	pig	NNS
cord-022561-rv5j1201	2780	7	with	with	IN
cord-022561-rv5j1201	2780	8	classical	classical	JJ
cord-022561-rv5j1201	2780	9	swine	swine	NN
cord-022561-rv5j1201	2780	10	fever	fever	NN
cord-022561-rv5j1201	2780	11	.	.	.
cord-022561-rv5j1201	2781	1	Acute	acute	JJ
cord-022561-rv5j1201	2781	2	splenic	splenic	JJ
cord-022561-rv5j1201	2781	3	infarcts	infarct	NNS
cord-022561-rv5j1201	2781	4	may	may	MD
cord-022561-rv5j1201	2781	5	not	not	RB
cord-022561-rv5j1201	2781	6	always	always	RB
cord-022561-rv5j1201	2781	7	be	be	VB
cord-022561-rv5j1201	2781	8	grossly	grossly	RB
cord-022561-rv5j1201	2781	9	visible	visible	JJ
cord-022561-rv5j1201	2781	10	in	in	IN
cord-022561-rv5j1201	2781	11	the	the	DT
cord-022561-rv5j1201	2781	12	early	early	JJ
cord-022561-rv5j1201	2781	13	stages	stage	NNS
cord-022561-rv5j1201	2781	14	but	but	CC
cord-022561-rv5j1201	2781	15	develop	develop	VB
cord-022561-rv5j1201	2781	16	into	into	IN
cord-022561-rv5j1201	2781	17	discrete	discrete	JJ
cord-022561-rv5j1201	2781	18	,	,	,
cord-022561-rv5j1201	2781	19	dark	dark	JJ
cord-022561-rv5j1201	2781	20	red	red	JJ
cord-022561-rv5j1201	2781	21	and	and	CC
cord-022561-rv5j1201	2781	22	blood	blood	NN
cord-022561-rv5j1201	2781	23	-	-	HYPH
cord-022561-rv5j1201	2781	24	filled	fill	VBN
cord-022561-rv5j1201	2781	25	,	,	,
cord-022561-rv5j1201	2781	26	bulging	bulge	VBG
cord-022561-rv5j1201	2781	27	,	,	,
cord-022561-rv5j1201	2781	28	wedge	wedge	NN
cord-022561-rv5j1201	2781	29	-	-	HYPH
cord-022561-rv5j1201	2781	30	shaped	shape	VBN
cord-022561-rv5j1201	2781	31	foci	foci	NN
cord-022561-rv5j1201	2781	32	with	with	IN
cord-022561-rv5j1201	2781	33	the	the	DT
cord-022561-rv5j1201	2781	34	base	base	NN
cord-022561-rv5j1201	2781	35	toward	toward	IN
cord-022561-rv5j1201	2781	36	the	the	DT
cord-022561-rv5j1201	2781	37	splenic	splenic	JJ
cord-022561-rv5j1201	2781	38	capsule	capsule	NN
cord-022561-rv5j1201	2782	1	(	(	-LRB-
cord-022561-rv5j1201	2782	2	Fig	Fig	NNP
cord-022561-rv5j1201	2782	3	.	.	.
cord-022561-rv5j1201	2782	4	13	13	CD
cord-022561-rv5j1201	2782	5	-	-	SYM
cord-022561-rv5j1201	2782	6	64	64	CD
cord-022561-rv5j1201	2782	7	,	,	,
cord-022561-rv5j1201	2782	8	A	A	NNP
cord-022561-rv5j1201	2782	9	)	)	-RRB-
cord-022561-rv5j1201	2782	10	.	.	.
cord-022561-rv5j1201	2783	1	With	with	IN
cord-022561-rv5j1201	2783	2	chronicity	chronicity	NN
cord-022561-rv5j1201	2783	3	the	the	DT
cord-022561-rv5j1201	2783	4	lesion	lesion	NN
cord-022561-rv5j1201	2783	5	becomes	become	VBZ
cord-022561-rv5j1201	2783	6	gray	gray	JJ
cord-022561-rv5j1201	2783	7	-	-	HYPH
cord-022561-rv5j1201	2783	8	white	white	JJ
cord-022561-rv5j1201	2783	9	and	and	CC
cord-022561-rv5j1201	2783	10	contracted	contract	VBD
cord-022561-rv5j1201	2783	11	due	due	IN
cord-022561-rv5j1201	2783	12	to	to	IN
cord-022561-rv5j1201	2783	13	fibrosis	fibrosis	NN
cord-022561-rv5j1201	2783	14	(	(	-LRB-
cord-022561-rv5j1201	2783	15	see	see	VB
cord-022561-rv5j1201	2783	16	Fig	Fig	NNP
cord-022561-rv5j1201	2783	17	.	.	.
cord-022561-rv5j1201	2784	1	13	13	CD
cord-022561-rv5j1201	2784	2	-64	-64	NNS
cord-022561-rv5j1201	2784	3	,	,	,
cord-022561-rv5j1201	2784	4	B).Hemangiosarcoma	B).Hemangiosarcoma	NNP
cord-022561-rv5j1201	2784	5	.	.	.
cord-022561-rv5j1201	2785	1	Hemangiosarcoma	Hemangiosarcoma	NNP
cord-022561-rv5j1201	2785	2	is	be	VBZ
cord-022561-rv5j1201	2785	3	a	a	DT
cord-022561-rv5j1201	2785	4	malignant	malignant	JJ
cord-022561-rv5j1201	2785	5	neoplasm	neoplasm	NN
cord-022561-rv5j1201	2785	6	of	of	IN
cord-022561-rv5j1201	2785	7	endothelial	endothelial	JJ
cord-022561-rv5j1201	2785	8	cells	cell	NNS
cord-022561-rv5j1201	2785	9	and	and	CC
cord-022561-rv5j1201	2785	10	is	be	VBZ
cord-022561-rv5j1201	2785	11	a	a	DT
cord-022561-rv5j1201	2785	12	common	common	JJ
cord-022561-rv5j1201	2785	13	primary	primary	JJ
cord-022561-rv5j1201	2785	14	tumor	tumor	NN
cord-022561-rv5j1201	2785	15	of	of	IN
cord-022561-rv5j1201	2785	16	the	the	DT
cord-022561-rv5j1201	2785	17	spleen	spleen	NN
cord-022561-rv5j1201	2785	18	,	,	,
cord-022561-rv5j1201	2785	19	especially	especially	RB
cord-022561-rv5j1201	2785	20	in	in	IN
cord-022561-rv5j1201	2785	21	dogs	dog	NNS
cord-022561-rv5j1201	2785	22	.	.	.
cord-022561-rv5j1201	2786	1	Benign	benign	JJ
cord-022561-rv5j1201	2786	2	splenic	splenic	JJ
cord-022561-rv5j1201	2786	3	hemangiomas	hemangiomas	NN
cord-022561-rv5j1201	2786	4	are	be	VBP
cord-022561-rv5j1201	2786	5	extraordinarily	extraordinarily	RB
cord-022561-rv5j1201	2786	6	rare	rare	JJ
cord-022561-rv5j1201	2786	7	.	.	.
cord-022561-rv5j1201	2787	1	Grossly	grossly	RB
cord-022561-rv5j1201	2787	2	,	,	,
cord-022561-rv5j1201	2787	3	hemangiosarcomas	hemangiosarcomas	NN
cord-022561-rv5j1201	2787	4	may	may	MD
cord-022561-rv5j1201	2787	5	appear	appear	VB
cord-022561-rv5j1201	2787	6	as	as	RB
cord-022561-rv5j1201	2787	7	single	single	JJ
cord-022561-rv5j1201	2787	8	,	,	,
cord-022561-rv5j1201	2787	9	multifocal	multifocal	JJ
cord-022561-rv5j1201	2787	10	,	,	,
cord-022561-rv5j1201	2787	11	or	or	CC
cord-022561-rv5j1201	2787	12	coalescing	coalesce	VBG
cord-022561-rv5j1201	2787	13	dark	dark	JJ
cord-022561-rv5j1201	2787	14	red	red	JJ
cord-022561-rv5j1201	2787	15	-	-	HYPH
cord-022561-rv5j1201	2787	16	purple	purple	JJ
cord-022561-rv5j1201	2787	17	masses	masse	NNS
cord-022561-rv5j1201	2787	18	and	and	CC
cord-022561-rv5j1201	2787	19	can	can	MD
cord-022561-rv5j1201	2787	20	not	not	RB
cord-022561-rv5j1201	2787	21	be	be	VB
cord-022561-rv5j1201	2787	22	easily	easily	RB
cord-022561-rv5j1201	2787	23	differentiated	differentiate	VBN
cord-022561-rv5j1201	2787	24	from	from	IN
cord-022561-rv5j1201	2787	25	a	a	DT
cord-022561-rv5j1201	2787	26	hematoma	hematoma	NN
cord-022561-rv5j1201	2787	27	(	(	-LRB-
cord-022561-rv5j1201	2787	28	Fig	Fig	NNP
cord-022561-rv5j1201	2787	29	.	.	.
cord-022561-rv5j1201	2787	30	13	13	CD
cord-022561-rv5j1201	2787	31	-	-	SYM
cord-022561-rv5j1201	2787	32	65	65	CD
cord-022561-rv5j1201	2787	33	)	)	-RRB-
cord-022561-rv5j1201	2787	34	.	.	.
cord-022561-rv5j1201	2788	1	On	on	IN
cord-022561-rv5j1201	2788	2	cut	cut	NN
cord-022561-rv5j1201	2788	3	surface	surface	NN
cord-022561-rv5j1201	2788	4	they	-PRON-	PRP
cord-022561-rv5j1201	2788	5	are	be	VBP
cord-022561-rv5j1201	2788	6	bloody	bloody	JJ
cord-022561-rv5j1201	2788	7	with	with	IN
cord-022561-rv5j1201	2788	8	varying	vary	VBG
cord-022561-rv5j1201	2788	9	amounts	amount	NNS
cord-022561-rv5j1201	2788	10	of	of	IN
cord-022561-rv5j1201	2788	11	soft	soft	JJ
cord-022561-rv5j1201	2788	12	red	red	JJ
cord-022561-rv5j1201	2788	13	neoplastic	neoplastic	JJ
cord-022561-rv5j1201	2788	14	tissue	tissue	NN
cord-022561-rv5j1201	2788	15	;	;	:
cord-022561-rv5j1201	2788	16	in	in	IN
cord-022561-rv5j1201	2788	17	more	more	RBR
cord-022561-rv5j1201	2788	18	solid	solid	JJ
cord-022561-rv5j1201	2788	19	areas	area	NNS
cord-022561-rv5j1201	2788	20	the	the	DT
cord-022561-rv5j1201	2788	21	neoplasm	neoplasm	NN
cord-022561-rv5j1201	2788	22	can	can	MD
cord-022561-rv5j1201	2788	23	be	be	VB
cord-022561-rv5j1201	2788	24	slightly	slightly	RB
cord-022561-rv5j1201	2788	25	more	more	RBR
cord-022561-rv5j1201	2788	26	firm	firm	JJ
cord-022561-rv5j1201	2788	27	and	and	CC
cord-022561-rv5j1201	2788	28	whitetan	whitetan	NNP
cord-022561-rv5j1201	2788	29	.	.	.
cord-022561-rv5j1201	2789	1	Metastatic	metastatic	JJ
cord-022561-rv5j1201	2789	2	spread	spread	NN
cord-022561-rv5j1201	2789	3	occurs	occur	VBZ
cord-022561-rv5j1201	2789	4	early	early	RB
cord-022561-rv5j1201	2789	5	in	in	IN
cord-022561-rv5j1201	2789	6	the	the	DT
cord-022561-rv5j1201	2789	7	disease	disease	NN
cord-022561-rv5j1201	2789	8	process	process	NN
cord-022561-rv5j1201	2789	9	.	.	.
cord-022561-rv5j1201	2790	1	Seeding	seed	VBG
cord-022561-rv5j1201	2790	2	of	of	IN
cord-022561-rv5j1201	2790	3	the	the	DT
cord-022561-rv5j1201	2790	4	peritoneum	peritoneum	NN
cord-022561-rv5j1201	2790	5	results	result	NNS
cord-022561-rv5j1201	2790	6	in	in	IN
cord-022561-rv5j1201	2790	7	numerous	numerous	JJ
cord-022561-rv5j1201	2790	8	discrete	discrete	JJ
cord-022561-rv5j1201	2790	9	red	red	JJ
cord-022561-rv5j1201	2790	10	-	-	HYPH
cord-022561-rv5j1201	2790	11	black	black	JJ
cord-022561-rv5j1201	2790	12	masses	masse	NNS
cord-022561-rv5j1201	2790	13	throughout	throughout	IN
cord-022561-rv5j1201	2790	14	the	the	DT
cord-022561-rv5j1201	2790	15	omentum	omentum	NN
cord-022561-rv5j1201	2790	16	and	and	CC
cord-022561-rv5j1201	2790	17	serosa	serosa	NN
cord-022561-rv5j1201	2790	18	of	of	IN
cord-022561-rv5j1201	2790	19	abdominal	abdominal	JJ
cord-022561-rv5j1201	2790	20	organs	organ	NNS
cord-022561-rv5j1201	2790	21	,	,	,
cord-022561-rv5j1201	2790	22	and	and	CC
cord-022561-rv5j1201	2790	23	hematogenous	hematogenous	NNP
cord-022561-rv5j1201	2790	24	spread	spread	VBD
cord-022561-rv5j1201	2790	25	to	to	IN
cord-022561-rv5j1201	2790	26	liver	liver	NN
cord-022561-rv5j1201	2790	27	and	and	CC
cord-022561-rv5j1201	2790	28	lung	lung	NN
cord-022561-rv5j1201	2790	29	are	be	VBP
cord-022561-rv5j1201	2790	30	common	common	JJ
cord-022561-rv5j1201	2790	31	.	.	.
cord-022561-rv5j1201	2791	1	Hemangiosarcomas	Hemangiosarcomas	NNP
cord-022561-rv5j1201	2791	2	in	in	IN
cord-022561-rv5j1201	2791	3	dogs	dog	NNS
cord-022561-rv5j1201	2791	4	also	also	RB
cord-022561-rv5j1201	2791	5	occur	occur	VBP
cord-022561-rv5j1201	2791	6	in	in	IN
cord-022561-rv5j1201	2791	7	the	the	DT
cord-022561-rv5j1201	2791	8	right	right	JJ
cord-022561-rv5j1201	2791	9	atrium	atrium	NN
cord-022561-rv5j1201	2791	10	of	of	IN
cord-022561-rv5j1201	2791	11	the	the	DT
cord-022561-rv5j1201	2791	12	heart	heart	NN
cord-022561-rv5j1201	2791	13	,	,	,
cord-022561-rv5j1201	2791	14	retroperitoneal	retroperitoneal	JJ
cord-022561-rv5j1201	2791	15	fat	fat	NN
cord-022561-rv5j1201	2791	16	,	,	,
cord-022561-rv5j1201	2791	17	and	and	CC
cord-022561-rv5j1201	2791	18	skin	skin	NN
cord-022561-rv5j1201	2791	19	(	(	-LRB-
cord-022561-rv5j1201	2791	20	dermal	dermal	JJ
cord-022561-rv5j1201	2791	21	and/or	and/or	CC
cord-022561-rv5j1201	2791	22	subcutaneous	subcutaneous	JJ
cord-022561-rv5j1201	2791	23	)	)	-RRB-
cord-022561-rv5j1201	2791	24	and	and	CC
cord-022561-rv5j1201	2791	25	multiorgan	multiorgan	NNP
cord-022561-rv5j1201	2791	26	hemangiosarcomas	hemangiosarcomas	NNP
cord-022561-rv5j1201	2791	27	are	be	VBP
cord-022561-rv5j1201	2791	28	described	describe	VBN
cord-022561-rv5j1201	2791	29	in	in	IN
cord-022561-rv5j1201	2791	30	horses	horse	NNS
cord-022561-rv5j1201	2791	31	,	,	,
cord-022561-rv5j1201	2791	32	cats	cat	NNS
cord-022561-rv5j1201	2791	33	,	,	,
cord-022561-rv5j1201	2791	34	and	and	CC
cord-022561-rv5j1201	2791	35	cattle	cattle	NNS
cord-022561-rv5j1201	2791	36	.	.	.
cord-022561-rv5j1201	2792	1	Because	because	IN
cord-022561-rv5j1201	2792	2	hemangiosarcomas	hemangiosarcomas	NNP
cord-022561-rv5j1201	2792	3	have	have	VBP
cord-022561-rv5j1201	2792	4	often	often	RB
cord-022561-rv5j1201	2792	5	metastasized	metastasize	VBN
cord-022561-rv5j1201	2792	6	at	at	IN
cord-022561-rv5j1201	2792	7	the	the	DT
cord-022561-rv5j1201	2792	8	time	time	NN
cord-022561-rv5j1201	2792	9	of	of	IN
cord-022561-rv5j1201	2792	10	initial	initial	JJ
cord-022561-rv5j1201	2792	11	accumulations	accumulation	NNS
cord-022561-rv5j1201	2792	12	of	of	IN
cord-022561-rv5j1201	2792	13	macrophages	macrophage	NNS
cord-022561-rv5j1201	2792	14	within	within	IN
cord-022561-rv5j1201	2792	15	several	several	JJ
cord-022561-rv5j1201	2792	16	organs	organ	NNS
cord-022561-rv5j1201	2792	17	,	,	,
cord-022561-rv5j1201	2792	18	including	include	VBG
cord-022561-rv5j1201	2792	19	splenic	splenic	JJ
cord-022561-rv5j1201	2792	20	macrophages	macrophage	NNS
cord-022561-rv5j1201	2792	21	,	,	,
cord-022561-rv5j1201	2792	22	Kupffer	Kupffer	NNP
cord-022561-rv5j1201	2792	23	cells	cell	NNS
cord-022561-rv5j1201	2792	24	of	of	IN
cord-022561-rv5j1201	2792	25	the	the	DT
cord-022561-rv5j1201	2792	26	liver	liver	NN
cord-022561-rv5j1201	2792	27	,	,	,
cord-022561-rv5j1201	2792	28	and	and	CC
cord-022561-rv5j1201	2792	29	macrophages	macrophage	NNS
cord-022561-rv5j1201	2792	30	in	in	IN
cord-022561-rv5j1201	2792	31	the	the	DT
cord-022561-rv5j1201	2792	32	brain	brain	NN
cord-022561-rv5j1201	2792	33	are	be	VBP
cord-022561-rv5j1201	2792	34	often	often	RB
cord-022561-rv5j1201	2792	35	observed	observe	VBN
cord-022561-rv5j1201	2792	36	.	.	.
cord-022561-rv5j1201	2793	1	Splenic	Splenic	NNP
cord-022561-rv5j1201	2793	2	Nodules	Nodules	NNP
cord-022561-rv5j1201	2793	3	with	with	IN
cord-022561-rv5j1201	2793	4	a	a	DT
cord-022561-rv5j1201	2793	5	Bloody	Bloody	NNP
cord-022561-rv5j1201	2793	6	Consistency	Consistency	NNP
cord-022561-rv5j1201	2793	7	.	.	.
cord-022561-rv5j1201	2794	1	The	the	DT
cord-022561-rv5j1201	2794	2	most	most	RBS
cord-022561-rv5j1201	2794	3	common	common	JJ
cord-022561-rv5j1201	2794	4	disorders	disorder	NNS
cord-022561-rv5j1201	2794	5	of	of	IN
cord-022561-rv5j1201	2794	6	the	the	DT
cord-022561-rv5j1201	2794	7	spleen	spleen	NN
cord-022561-rv5j1201	2794	8	with	with	IN
cord-022561-rv5j1201	2794	9	bloody	bloody	JJ
cord-022561-rv5j1201	2794	10	nodules	nodule	NNS
cord-022561-rv5j1201	2794	11	are	be	VBP
cord-022561-rv5j1201	2794	12	(	(	-LRB-
cord-022561-rv5j1201	2794	13	1	1	CD
cord-022561-rv5j1201	2794	14	)	)	-RRB-
cord-022561-rv5j1201	2794	15	hematomas	hematoma	NNS
cord-022561-rv5j1201	2794	16	,	,	,
cord-022561-rv5j1201	2794	17	including	include	VBG
cord-022561-rv5j1201	2794	18	those	those	DT
cord-022561-rv5j1201	2794	19	induced	induce	VBN
cord-022561-rv5j1201	2794	20	by	by	IN
cord-022561-rv5j1201	2794	21	nodular	nodular	JJ
cord-022561-rv5j1201	2794	22	hyperplasia	hyperplasia	NN
cord-022561-rv5j1201	2794	23	or	or	CC
cord-022561-rv5j1201	2794	24	occurring	occur	VBG
cord-022561-rv5j1201	2794	25	with	with	IN
cord-022561-rv5j1201	2794	26	hemangiosarcoma	hemangiosarcoma	NN
cord-022561-rv5j1201	2794	27	,	,	,
cord-022561-rv5j1201	2794	28	(	(	-LRB-
cord-022561-rv5j1201	2794	29	2	2	LS
cord-022561-rv5j1201	2794	30	)	)	-RRB-
cord-022561-rv5j1201	2794	31	incompletely	incompletely	RB
cord-022561-rv5j1201	2794	32	contracted	contract	VBN
cord-022561-rv5j1201	2794	33	areas	area	NNS
cord-022561-rv5j1201	2794	34	of	of	IN
cord-022561-rv5j1201	2794	35	the	the	DT
cord-022561-rv5j1201	2794	36	spleen	spleen	NN
cord-022561-rv5j1201	2794	37	,	,	,
cord-022561-rv5j1201	2794	38	(	(	-LRB-
cord-022561-rv5j1201	2794	39	3	3	LS
cord-022561-rv5j1201	2794	40	)	)	-RRB-
cord-022561-rv5j1201	2794	41	acute	acute	JJ
cord-022561-rv5j1201	2794	42	splenic	splenic	JJ
cord-022561-rv5j1201	2794	43	infarcts	infarct	NNS
cord-022561-rv5j1201	2794	44	,	,	,
cord-022561-rv5j1201	2794	45	and	and	CC
cord-022561-rv5j1201	2794	46	(	(	-LRB-
cord-022561-rv5j1201	2794	47	4	4	LS
cord-022561-rv5j1201	2794	48	)	)	-RRB-
cord-022561-rv5j1201	2794	49	hemangiosarcomas	hemangiosarcomas	NNP
cord-022561-rv5j1201	2794	50	.	.	.
cord-022561-rv5j1201	2795	1	The	the	DT
cord-022561-rv5j1201	2795	2	term	term	NN
cord-022561-rv5j1201	2795	3	nodule	nodule	NN
cord-022561-rv5j1201	2795	4	has	have	VBZ
cord-022561-rv5j1201	2795	5	been	be	VBN
cord-022561-rv5j1201	2795	6	applied	apply	VBN
cord-022561-rv5j1201	2795	7	rather	rather	RB
cord-022561-rv5j1201	2795	8	loosely	loosely	RB
cord-022561-rv5j1201	2795	9	here	here	RB
cord-022561-rv5j1201	2795	10	.	.	.
cord-022561-rv5j1201	2796	1	In	in	IN
cord-022561-rv5j1201	2796	2	some	some	DT
cord-022561-rv5j1201	2796	3	of	of	IN
cord-022561-rv5j1201	2796	4	these	these	DT
cord-022561-rv5j1201	2796	5	conditions	condition	NNS
cord-022561-rv5j1201	2796	6	,	,	,
cord-022561-rv5j1201	2796	7	such	such	JJ
cord-022561-rv5j1201	2796	8	as	as	IN
cord-022561-rv5j1201	2796	9	incompletely	incompletely	RB
cord-022561-rv5j1201	2796	10	or	or	CC
cord-022561-rv5j1201	2796	11	irregularly	irregularly	RB
cord-022561-rv5j1201	2796	12	contracted	contract	VBN
cord-022561-rv5j1201	2796	13	areas	area	NNS
cord-022561-rv5j1201	2796	14	of	of	IN
cord-022561-rv5j1201	2796	15	the	the	DT
cord-022561-rv5j1201	2796	16	spleen	spleen	NN
cord-022561-rv5j1201	2796	17	,	,	,
cord-022561-rv5j1201	2796	18	the	the	DT
cord-022561-rv5j1201	2796	19	elevated	elevated	JJ
cord-022561-rv5j1201	2796	20	area	area	NN
cord-022561-rv5j1201	2796	21	of	of	IN
cord-022561-rv5j1201	2796	22	the	the	DT
cord-022561-rv5j1201	2796	23	spleen	spleen	NN
cord-022561-rv5j1201	2796	24	is	be	VBZ
cord-022561-rv5j1201	2796	25	not	not	RB
cord-022561-rv5j1201	2796	26	as	as	RB
cord-022561-rv5j1201	2796	27	well	well	RB
cord-022561-rv5j1201	2796	28	defined	define	VBN
cord-022561-rv5j1201	2796	29	as	as	IN
cord-022561-rv5j1201	2796	30	the	the	DT
cord-022561-rv5j1201	2796	31	term	term	NN
cord-022561-rv5j1201	2796	32	nodule	nodule	NN
cord-022561-rv5j1201	2796	33	would	would	MD
cord-022561-rv5j1201	2796	34	imply	imply	VB
cord-022561-rv5j1201	2796	35	.	.	.
cord-022561-rv5j1201	2797	1	Hematomas	Hematomas	NNP
cord-022561-rv5j1201	2797	2	.	.	.
cord-022561-rv5j1201	2798	1	Bleeding	bleed	VBG
cord-022561-rv5j1201	2798	2	into	into	IN
cord-022561-rv5j1201	2798	3	the	the	DT
cord-022561-rv5j1201	2798	4	red	red	JJ
cord-022561-rv5j1201	2798	5	pulp	pulp	NN
cord-022561-rv5j1201	2798	6	to	to	TO
cord-022561-rv5j1201	2798	7	form	form	VB
cord-022561-rv5j1201	2798	8	a	a	DT
cord-022561-rv5j1201	2798	9	hematoma	hematoma	NN
cord-022561-rv5j1201	2798	10	is	be	VBZ
cord-022561-rv5j1201	2798	11	confined	confine	VBN
cord-022561-rv5j1201	2798	12	by	by	IN
cord-022561-rv5j1201	2798	13	the	the	DT
cord-022561-rv5j1201	2798	14	splenic	splenic	JJ
cord-022561-rv5j1201	2798	15	capsule	capsule	NN
cord-022561-rv5j1201	2798	16	,	,	,
cord-022561-rv5j1201	2798	17	and	and	CC
cord-022561-rv5j1201	2798	18	produces	produce	VBZ
cord-022561-rv5j1201	2798	19	a	a	DT
cord-022561-rv5j1201	2798	20	red	red	NN
cord-022561-rv5j1201	2798	21	to	to	TO
cord-022561-rv5j1201	2798	22	dark	dark	JJ
cord-022561-rv5j1201	2798	23	red	red	JJ
cord-022561-rv5j1201	2798	24	,	,	,
cord-022561-rv5j1201	2798	25	soft	soft	JJ
cord-022561-rv5j1201	2798	26	,	,	,
cord-022561-rv5j1201	2798	27	bulging	bulge	VBG
cord-022561-rv5j1201	2798	28	,	,	,
cord-022561-rv5j1201	2798	29	usually	usually	RB
cord-022561-rv5j1201	2798	30	solitary	solitary	JJ
cord-022561-rv5j1201	2798	31	mass	mass	NN
cord-022561-rv5j1201	2798	32	of	of	IN
cord-022561-rv5j1201	2798	33	varying	vary	VBG
cord-022561-rv5j1201	2798	34	size	size	NN
cord-022561-rv5j1201	2798	35	(	(	-LRB-
cord-022561-rv5j1201	2798	36	2	2	CD
cord-022561-rv5j1201	2798	37	to	to	TO
cord-022561-rv5j1201	2798	38	15	15	CD
cord-022561-rv5j1201	2798	39	cm	cm	NNS
cord-022561-rv5j1201	2798	40	in	in	IN
cord-022561-rv5j1201	2798	41	diameter	diameter	NN
cord-022561-rv5j1201	2798	42	)	)	-RRB-
cord-022561-rv5j1201	2799	1	(	(	-LRB-
cord-022561-rv5j1201	2799	2	Fig	Fig	NNP
cord-022561-rv5j1201	2799	3	.	.	.
cord-022561-rv5j1201	2799	4	13	13	CD
cord-022561-rv5j1201	2799	5	-	-	SYM
cord-022561-rv5j1201	2799	6	62	62	CD
cord-022561-rv5j1201	2799	7	)	)	-RRB-
cord-022561-rv5j1201	2799	8	.	.	.
cord-022561-rv5j1201	2800	1	Resolution	resolution	NN
cord-022561-rv5j1201	2800	2	of	of	IN
cord-022561-rv5j1201	2800	3	a	a	DT
cord-022561-rv5j1201	2800	4	splenic	splenic	JJ
cord-022561-rv5j1201	2800	5	hematoma	hematoma	NN
cord-022561-rv5j1201	2800	6	progresses	progress	VBZ
cord-022561-rv5j1201	2800	7	over	over	IN
cord-022561-rv5j1201	2800	8	days	day	NNS
cord-022561-rv5j1201	2800	9	to	to	IN
cord-022561-rv5j1201	2800	10	weeks	week	NNS
cord-022561-rv5j1201	2800	11	,	,	,
cord-022561-rv5j1201	2800	12	through	through	IN
cord-022561-rv5j1201	2800	13	the	the	DT
cord-022561-rv5j1201	2800	14	stages	stage	NNS
cord-022561-rv5j1201	2800	15	of	of	IN
cord-022561-rv5j1201	2800	16	coagulation	coagulation	NN
cord-022561-rv5j1201	2800	17	and	and	CC
cord-022561-rv5j1201	2800	18	breakdown	breakdown	NN
cord-022561-rv5j1201	2800	19	of	of	IN
cord-022561-rv5j1201	2800	20	the	the	DT
cord-022561-rv5j1201	2800	21	blood	blood	NN
cord-022561-rv5j1201	2800	22	into	into	IN
cord-022561-rv5j1201	2800	23	a	a	DT
cord-022561-rv5j1201	2800	24	dark	dark	JJ
cord-022561-rv5j1201	2800	25	red	red	JJ
cord-022561-rv5j1201	2800	26	-	-	HYPH
cord-022561-rv5j1201	2800	27	brown	brown	JJ
cord-022561-rv5j1201	2800	28	soft	soft	JJ
cord-022561-rv5j1201	2800	29	mass	mass	NN
cord-022561-rv5j1201	2800	30	(	(	-LRB-
cord-022561-rv5j1201	2800	31	Fig	Fig	NNP
cord-022561-rv5j1201	2800	32	.	.	.
cord-022561-rv5j1201	2800	33	13	13	CD
cord-022561-rv5j1201	2800	34	-	-	SYM
cord-022561-rv5j1201	2800	35	63	63	CD
cord-022561-rv5j1201	2800	36	,	,	,
cord-022561-rv5j1201	2800	37	A	A	NNP
cord-022561-rv5j1201	2800	38	)	)	-RRB-
cord-022561-rv5j1201	2800	39	,	,	,
cord-022561-rv5j1201	2800	40	infiltration	infiltration	NN
cord-022561-rv5j1201	2800	41	by	by	IN
cord-022561-rv5j1201	2800	42	macrophages	macrophage	NNS
cord-022561-rv5j1201	2800	43	that	that	WDT
cord-022561-rv5j1201	2800	44	phagocytize	phagocytize	NNP
cord-022561-rv5j1201	2800	45	erythrocytes	erythrocyte	NNS
cord-022561-rv5j1201	2800	46	and	and	CC
cord-022561-rv5j1201	2800	47	break	break	VB
cord-022561-rv5j1201	2800	48	down	down	RP
cord-022561-rv5j1201	2800	49	hemoglobin	hemoglobin	NN
cord-022561-rv5j1201	2800	50	to	to	TO
cord-022561-rv5j1201	2800	51	form	form	VB
cord-022561-rv5j1201	2800	52	hematoidin	hematoidin	NNP
cord-022561-rv5j1201	2800	53	and	and	CC
cord-022561-rv5j1201	2800	54	hemosiderin	hemosiderin	NNP
cord-022561-rv5j1201	2800	55	(	(	-LRB-
cord-022561-rv5j1201	2800	56	see	see	VB
cord-022561-rv5j1201	2800	57	Fig	Fig	NNP
cord-022561-rv5j1201	2800	58	.	.	.
cord-022561-rv5j1201	2801	1	13	13	CD
cord-022561-rv5j1201	2801	2	-	-	SYM
cord-022561-rv5j1201	2801	3	63	63	CD
cord-022561-rv5j1201	2801	4	,	,	,
cord-022561-rv5j1201	2801	5	B	B	NNP
cord-022561-rv5j1201	2801	6	)	)	-RRB-
cord-022561-rv5j1201	2801	7	,	,	,
cord-022561-rv5j1201	2801	8	and	and	CC
cord-022561-rv5j1201	2801	9	repair	repair	VB
cord-022561-rv5j1201	2801	10	leading	lead	VBG
cord-022561-rv5j1201	2801	11	to	to	IN
cord-022561-rv5j1201	2801	12	fibrosis	fibrosis	NN
cord-022561-rv5j1201	2801	13	.	.	.
cord-022561-rv5j1201	2802	1	On	on	IN
cord-022561-rv5j1201	2802	2	occasion	occasion	NN
cord-022561-rv5j1201	2802	3	the	the	DT
cord-022561-rv5j1201	2802	4	capsule	capsule	NN
cord-022561-rv5j1201	2802	5	(	(	-LRB-
cord-022561-rv5j1201	2802	6	splenic	splenic	JJ
cord-022561-rv5j1201	2802	7	capsule	capsule	NN
cord-022561-rv5j1201	2802	8	and	and	CC
cord-022561-rv5j1201	2802	9	visceral	visceral	JJ
cord-022561-rv5j1201	2802	10	peritoneum	peritoneum	NN
cord-022561-rv5j1201	2802	11	)	)	-RRB-
cord-022561-rv5j1201	2802	12	over	over	IN
cord-022561-rv5j1201	2802	13	the	the	DT
cord-022561-rv5j1201	2802	14	hematoma	hematoma	NN
cord-022561-rv5j1201	2802	15	can	can	MD
cord-022561-rv5j1201	2802	16	rupture	rupture	VB
cord-022561-rv5j1201	2802	17	,	,	,
cord-022561-rv5j1201	2802	18	resulting	result	VBG
cord-022561-rv5j1201	2802	19	in	in	IN
cord-022561-rv5j1201	2802	20	hemoperitoneum	hemoperitoneum	NNP
cord-022561-rv5j1201	2802	21	,	,	,
cord-022561-rv5j1201	2802	22	hypovolemic	hypovolemic	JJ
cord-022561-rv5j1201	2802	23	shock	shock	NN
cord-022561-rv5j1201	2802	24	,	,	,
cord-022561-rv5j1201	2802	25	and	and	CC
cord-022561-rv5j1201	2802	26	death	death	NN
cord-022561-rv5j1201	2802	27	.	.	.
cord-022561-rv5j1201	2803	1	The	the	DT
cord-022561-rv5j1201	2803	2	origin	origin	NN
cord-022561-rv5j1201	2803	3	or	or	CC
cord-022561-rv5j1201	2803	4	cause	cause	NN
cord-022561-rv5j1201	2803	5	of	of	IN
cord-022561-rv5j1201	2803	6	many	many	JJ
cord-022561-rv5j1201	2803	7	hematomas	hematoma	NNS
cord-022561-rv5j1201	2803	8	is	be	VBZ
cord-022561-rv5j1201	2803	9	unknown	unknown	JJ
cord-022561-rv5j1201	2803	10	.	.	.
cord-022561-rv5j1201	2804	1	Some	some	DT
cord-022561-rv5j1201	2804	2	are	be	VBP
cord-022561-rv5j1201	2804	3	due	due	JJ
cord-022561-rv5j1201	2804	4	to	to	IN
cord-022561-rv5j1201	2804	5	trauma	trauma	NN
cord-022561-rv5j1201	2804	6	,	,	,
cord-022561-rv5j1201	2804	7	and	and	CC
cord-022561-rv5j1201	2804	8	others	other	NNS
cord-022561-rv5j1201	2804	9	may	may	MD
cord-022561-rv5j1201	2804	10	also	also	RB
cord-022561-rv5j1201	2804	11	be	be	VB
cord-022561-rv5j1201	2804	12	induced	induce	VBN
cord-022561-rv5j1201	2804	13	by	by	IN
cord-022561-rv5j1201	2804	14	splenic	splenic	JJ
cord-022561-rv5j1201	2804	15	nodular	nodular	JJ
cord-022561-rv5j1201	2804	16	hyperplasia	hyperplasia	NN
cord-022561-rv5j1201	2804	17	.	.	.
cord-022561-rv5j1201	2805	1	It	-PRON-	PRP
cord-022561-rv5j1201	2805	2	is	be	VBZ
cord-022561-rv5j1201	2805	3	postulated	postulate	VBN
cord-022561-rv5j1201	2805	4	that	that	IN
cord-022561-rv5j1201	2805	5	as	as	IN
cord-022561-rv5j1201	2805	6	the	the	DT
cord-022561-rv5j1201	2805	7	splenic	splenic	JJ
cord-022561-rv5j1201	2805	8	follicles	follicle	NNS
cord-022561-rv5j1201	2805	9	become	become	VBP
cord-022561-rv5j1201	2805	10	hyperplastic	hyperplastic	JJ
cord-022561-rv5j1201	2805	11	they	-PRON-	PRP
cord-022561-rv5j1201	2805	12	distort	distort	VBP
cord-022561-rv5j1201	2805	13	the	the	DT
cord-022561-rv5j1201	2805	14	adjacent	adjacent	JJ
cord-022561-rv5j1201	2805	15	marginal	marginal	JJ
cord-022561-rv5j1201	2805	16	zone	zone	NN
cord-022561-rv5j1201	2805	17	and	and	CC
cord-022561-rv5j1201	2805	18	marginal	marginal	JJ
cord-022561-rv5j1201	2805	19	sinus	sinus	NN
cord-022561-rv5j1201	2805	20	,	,	,
cord-022561-rv5j1201	2805	21	which	which	WDT
cord-022561-rv5j1201	2805	22	compromises	compromise	VBZ
cord-022561-rv5j1201	2805	23	their	-PRON-	PRP$
cord-022561-rv5j1201	2805	24	drainage	drainage	NN
cord-022561-rv5j1201	2805	25	into	into	IN
cord-022561-rv5j1201	2805	26	sinusoids	sinusoid	NNS
cord-022561-rv5j1201	2805	27	and	and	CC
cord-022561-rv5j1201	2805	28	red	red	JJ
cord-022561-rv5j1201	2805	29	pulp	pulp	NN
cord-022561-rv5j1201	2805	30	vascular	vascular	JJ
cord-022561-rv5j1201	2805	31	spaces	space	NNS
cord-022561-rv5j1201	2805	32	.	.	.
cord-022561-rv5j1201	2806	1	The	the	DT
cord-022561-rv5j1201	2806	2	result	result	NN
cord-022561-rv5j1201	2806	3	is	be	VBZ
cord-022561-rv5j1201	2806	4	an	an	DT
cord-022561-rv5j1201	2806	5	accumulation	accumulation	NN
cord-022561-rv5j1201	2806	6	of	of	IN
cord-022561-rv5j1201	2806	7	pooled	pool	VBN
cord-022561-rv5j1201	2806	8	blood	blood	NN
cord-022561-rv5j1201	2806	9	surrounding	surround	VBG
cord-022561-rv5j1201	2806	10	the	the	DT
cord-022561-rv5j1201	2806	11	hyperplastic	hyperplastic	JJ
cord-022561-rv5j1201	2806	12	nodule	nodule	NN
cord-022561-rv5j1201	2806	13	,	,	,
cord-022561-rv5j1201	2806	14	which	which	WDT
cord-022561-rv5j1201	2806	15	leads	lead	VBZ
cord-022561-rv5j1201	2806	16	to	to	IN
cord-022561-rv5j1201	2806	17	hematoma	hematoma	NN
cord-022561-rv5j1201	2806	18	formation	formation	NN
cord-022561-rv5j1201	2806	19	.	.	.
cord-022561-rv5j1201	2807	1	Splenic	splenic	JJ
cord-022561-rv5j1201	2807	2	hematomas	hematoma	NNS
cord-022561-rv5j1201	2807	3	can	can	MD
cord-022561-rv5j1201	2807	4	also	also	RB
cord-022561-rv5j1201	2807	5	occur	occur	VB
cord-022561-rv5j1201	2807	6	secondary	secondary	JJ
cord-022561-rv5j1201	2807	7	to	to	IN
cord-022561-rv5j1201	2807	8	the	the	DT
cord-022561-rv5j1201	2807	9	rupture	rupture	NN
cord-022561-rv5j1201	2807	10	of	of	IN
cord-022561-rv5j1201	2807	11	hemangiosarcomas	hemangiosarcomas	NN
cord-022561-rv5j1201	2807	12	within	within	IN
cord-022561-rv5j1201	2807	13	the	the	DT
cord-022561-rv5j1201	2807	14	spleen	spleen	NN
cord-022561-rv5j1201	2807	15	.	.	.
cord-022561-rv5j1201	2808	1	Incompletely	incompletely	RB
cord-022561-rv5j1201	2808	2	Contracted	contract	VBN
cord-022561-rv5j1201	2808	3	Areas	Areas	NNPS
cord-022561-rv5j1201	2808	4	of	of	IN
cord-022561-rv5j1201	2808	5	the	the	DT
cord-022561-rv5j1201	2808	6	Spleen	Spleen	NNP
cord-022561-rv5j1201	2808	7	.	.	.
cord-022561-rv5j1201	2809	1	Incompletely	incompletely	RB
cord-022561-rv5j1201	2809	2	or	or	CC
cord-022561-rv5j1201	2809	3	irregularly	irregularly	RB
cord-022561-rv5j1201	2809	4	contracted	contract	VBN
cord-022561-rv5j1201	2809	5	areas	area	NNS
cord-022561-rv5j1201	2809	6	of	of	IN
cord-022561-rv5j1201	2809	7	the	the	DT
cord-022561-rv5j1201	2809	8	spleen	spleen	NNS
cord-022561-rv5j1201	2809	9	are	be	VBP
cord-022561-rv5j1201	2809	10	caused	cause	VBN
cord-022561-rv5j1201	2809	11	by	by	IN
cord-022561-rv5j1201	2809	12	failure	failure	NN
cord-022561-rv5j1201	2809	13	of	of	IN
cord-022561-rv5j1201	2809	14	the	the	DT
cord-022561-rv5j1201	2809	15	smooth	smooth	JJ
cord-022561-rv5j1201	2809	16	muscle	muscle	NN
cord-022561-rv5j1201	2809	17	to	to	TO
cord-022561-rv5j1201	2809	18	contract	contract	NN
cord-022561-rv5j1201	2809	19	in	in	IN
cord-022561-rv5j1201	2809	20	response	response	NN
cord-022561-rv5j1201	2809	21	to	to	IN
cord-022561-rv5j1201	2809	22	circulatory	circulatory	JJ
cord-022561-rv5j1201	2809	23	shock	shock	NN
cord-022561-rv5j1201	2809	24	(	(	-LRB-
cord-022561-rv5j1201	2809	25	hypovolemic	hypovolemic	JJ
cord-022561-rv5j1201	2809	26	,	,	,
cord-022561-rv5j1201	2809	27	cardiogenic	cardiogenic	JJ
cord-022561-rv5j1201	2809	28	,	,	,
cord-022561-rv5j1201	2809	29	or	or	CC
cord-022561-rv5j1201	2809	30	septic	septic	NN
cord-022561-rv5j1201	2809	31	)	)	-RRB-
cord-022561-rv5j1201	2809	32	or	or	CC
cord-022561-rv5j1201	2809	33	sympathetic	sympathetic	JJ
cord-022561-rv5j1201	2809	34	"	"	``
cord-022561-rv5j1201	2809	35	fight	fight	NN
cord-022561-rv5j1201	2809	36	-	-	HYPH
cord-022561-rv5j1201	2809	37	or	or	CC
cord-022561-rv5j1201	2809	38	-	-	HYPH
cord-022561-rv5j1201	2809	39	flight	flight	NN
cord-022561-rv5j1201	2809	40	"	"	''
cord-022561-rv5j1201	2809	41	response	response	NN
cord-022561-rv5j1201	2809	42	,	,	,
cord-022561-rv5j1201	2809	43	resulting	result	VBG
cord-022561-rv5j1201	2809	44	in	in	IN
cord-022561-rv5j1201	2809	45	a	a	DT
cord-022561-rv5j1201	2809	46	lack	lack	NN
cord-022561-rv5j1201	2809	47	of	of	IN
cord-022561-rv5j1201	2809	48	splenic	splenic	JJ
cord-022561-rv5j1201	2809	49	evacuation	evacuation	NN
cord-022561-rv5j1201	2809	50	of	of	IN
cord-022561-rv5j1201	2809	51	stored	store	VBN
cord-022561-rv5j1201	2809	52	blood	blood	NN
cord-022561-rv5j1201	2809	53	.	.	.
cord-022561-rv5j1201	2809	54	 	 	_SP