id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-261311-j6bmgmhz	Parreiras Martins, Maria Auxiliadora	Preparedness of pharmacists to respond to the emergency of the COVID-19 pandemic in Brazil: a comprehensive overview	2020-07-31		.txt	text/plain	4307	206	37	COVID-19 patients may present high risk in the use of medications and clinical pharmacists can contribute substantially as part of a multidisciplinary team to improve outcomes in drug therapy in severe and critical illness. The course of an intense inflammatory process leads to alterations in many Review of patients' medical history Provision of real-time assessment and evidence-based (when possible) advice on drug therapy Support on safe use of medications brought from home Medication reconciliation at different levels of transition of care Simplification of drug administration schedule to reduce the exposure of nurses to COVID-19 patients Monitoring of potential drug-drug, drug-food interactions and adverse drug reactions Adjustments in dosing regimens according to liver and kidney functions Prevention of medication errors Optimization of drug therapy and electrolytes to minimize the risk of prolonged corrected QT intervals and torsade de pointes Support on lung-protective ventilation and neuromuscular blocking agents to facilitate ventilator synchrony Provision of conservative fluid strategies and monitoring of vasopressors use Monitoring of empirical antibiotics for suspected bacterial co-infection with rigorous de-escalation Employment of FASTHUG-MAIDENS mnemonic to identify drug-related problems in intensive care units Support on drug information to patients and multidisciplinary teams, following biosafety protocols Considerations on special situations (pediatrics, older adults, people with chronic diseases, allergies) Research and continuing education Precise documentation of pharmaceutical interventions laboratory tests in patients with acute or severe/critical illness.	./cache/cord-261311-j6bmgmhz.txt	./txt/cord-261311-j6bmgmhz.txt