id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-022597-9b1a8cri	nan	Hematopoietic Tumors	2009-05-15		.txt	text/plain	39255	2396	46	Hepatosplenic lymphoma is a relatively uncommon, distinct presentation in the dog marked by a lack of peripheral lymphadenopathy in the face of hepatic, splenic, and bone marrow infiltration with malignant lymphocytes, usually of T-cell origin. The prognosis for canine lymphoma varies and depends on a number of factors, such as the location of disease, the extent of disease (the clinical stage), the presence or absence of clinical signs (the substage), the histologic grade, the immunophenotype (T cell or B cell), exposure to previous chemotherapy or corticosteroids and subsequent development of MDR (see Chapter 11), altered cell death processes (apoptosis), the proliferation rate of the tumor, the presence of concurrent medical problems or paraneoplastic conditions (e.g., hypercalcemia, weight loss, and liver insufficiency), and possibly gender.* Although canine lymphoma is rarely curable (fewer than 10% of cases), complete responses and a good quality of life during extended remissions and survival are typical.	./cache/cord-022597-9b1a8cri.txt	./txt/cord-022597-9b1a8cri.txt