id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-255814-k203h9jq	Abou-Al-Shaar, Hussam	The Undetermined Destiny of Case Reports in the Era of Sophisticated Medicine	2017-05-31		.txt	text/plain	857	60	51	In 1910, Dr. Harvey Cushing first encountered the disease in a 23-year-old woman, who is historically known as "Minnie G." The patient had an unusual and complex clinical presentation in the form of obesity, hypertrichosis, amenorrhea, overdevelopment of secondary sexual characteristics, low-grade hydrocephalus, and increased cerebral tension. 4 Because of such single case reports, the clinical symptoms of the disease were described and were named after Cushing. 6 The disease was initially described as a single case, and extensive reporting of more cases expanded our understanding of the nature of such an infection, its origin, route of transmission, pathophysiologic mechanisms, and clinical implications. 7 The value of case reports is also evident by their role in delineating hidden unusual disease associations, 8, 9 novel genetic discoveries, 10 new surgical techniques and technical nuances, 11 unique thought-provoking disease pathogenesis, 12 decision-making challenges and conundrums, 13 cutting-edge management innovations, 14 and unusual complications.	./cache/cord-255814-k203h9jq.txt	./txt/cord-255814-k203h9jq.txt