id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-283749-j4600733	Itoyama, Satoru	ACE1 polymorphism and progression of SARS	2004-10-22		.txt	text/plain	2975	152	53	Angiotensin converting enzyme (ACE1) insertion/deletion (I/D) polymorphism was previously reported to show association with the adult respiratory distress syndrome, which is also thought to play a key role in damaging the lung tissues in SARS cases. Despite the small sample size, the frequency of the D allele was significantly higher in the hypoxemic group than in the non-hypoxemic group (p =0.013), whereas there was no significant difference between the SARS cases and controls, irrespective of a contact history. Genotypic distribution and allele frequency of the ACE I/D polymorphism in SARS cases and controls with or without contact history to SARS patients were compared (Table 4 ). The ACE insertion/deletion polymorphism has also been reported to be a risk factor of the diseases mentioned above [17] and this might be associated with systemic angiopathy and influence progression of SARS in the lung. Lung pathology of severe acute respiratory syndrome (SARS): a study of 8 autopsy cases from Singapore	./cache/cord-283749-j4600733.txt	./txt/cord-283749-j4600733.txt