id author title date pages extension mime words sentences flesch summary cache txt cord-292719-n5lg43tr Chang, Luan-Yin Viral infections associated with Kawasaki disease 2014-02-01 .txt text/plain 3163 169 47 To investigate the infectious etiology of Kawasaki disease, we initiated a prospective case-control study to investigate possible links between common viral infections and Kawasaki disease. The infectious evidence of Kawasaki disease includes temporal clustering and marked seasonality, geographic clustering, family clustering, a high association between Kawasaki disease and infectious disease surveillance, and age distribution, for which the highest incidence rates are seen among 6 monthe2-year-old children who have low maternal antibodies and are most susceptible to infections in general. We thus carried out a prospective case-control study to investigate the association of common viral infections with Kawasaki disease to test the above hypothesis. We enrolled Kawasaki disease cases that had fever for over 5 days and at least four of the following five manifestations: neck lymphadenopathy, lip fissure and/or strawberry tongue, skin rash, nonpurulent bulbar conjunctivitis, palm/sole erythema, and induration followed by periungual desquamation. The c 2 test was used to compare the rates of viral isolation and PCR of various viruses between KD cases and the control children. ./cache/cord-292719-n5lg43tr.txt ./txt/cord-292719-n5lg43tr.txt