id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-314120-zp9k1k3z	Brunner, Carolyn M.	Clinical and immunologic studies in identical twins discordant for systemic lupus erythematosus	1973-08-31		.txt	text/plain	2327	154	55	Abstract Middle-aged female identical twins, one of whom had systemic lupus erythematosus (SLE), were evaluated for immunologic reactivity to previous antigenic challenges, including primary immunization with a foreign antigen, keyhole limpet hemocyanin (KLH). Serologic studies were as follows: latex nucleoprotein 3+, lupus erythematosus cell preparation positive, hemolytic complement (C'H50) 28 units (normal range 34 to 48 units) and rheumatoid factor (RF) negative. Although antinuclear factor remained positive, a lupus erythematosus cell preparation was negative, and serum complement was normal. SLE as the etiology of the patient's nephritis (Case 1) was first suggested by the positive lupus erythematosus cell preparation in 1963. Multiple blood samples tested for lupus erythematosus cells, antinuclear factor, anti DNA, rheumatoid factor and cryoglobulins (Table I) Delayed hypersensitivity to common antigens was assessed by the intradermal injection of 0.1 ml of 1:40 streptokinase-streptodornase (SK-SD), (Varidasew, Lederle, Pearl River, N.Y.), 1:30 Trichophyton (Hollister Stier, Yeadon, Pa.) and 1 :lOO Candida albicans (Hollister Stier).	./cache/cord-314120-zp9k1k3z.txt	./txt/cord-314120-zp9k1k3z.txt