id author title date pages extension mime words sentences flesch summary cache txt cord-022569-ddaqfsmp Pappas, Diane E. The Common Cold 2013-02-10 .txt text/plain 2933 173 45 17, 18 Furthermore, in vitro studies have shown that rhinovirus and coronavirus produce no detectable cytopathic effect when replicating in a cultured monolayer of nasal epithelial cells, whereas influenza virus A and adenovirus produce obvious damage. 19 The symptoms of the common cold appear to result from release of cytokines and other mediators from infected nasal epithelial cells as well as from an influx of polymorphonuclear cells (PMNs). However, a recent study found that 20 children hospitalized for preseptal or orbital cellulitis, indicative of bacterial sinusitis, had symptoms of acute respiratory tract infection for 7 days or less prior to hospitalization, suggesting that the complications of rhinosinusitis can occur during the first few days of a cold. The symptoms of the common cold appear to result from effects of inflammatory mediators released in response to the viral infection of the respiratory tract. ./cache/cord-022569-ddaqfsmp.txt ./txt/cord-022569-ddaqfsmp.txt