id author title date pages extension mime words sentences flesch summary cache txt cord-263688-xz2hnym0 Varghese, Litty Epidemiology and Clinical Features of Human Coronaviruses in the Pediatric Population 2017-05-08 .txt text/plain 3513 168 46 The objectives of this study were to (1) characterize the epidemiology of HCoV detected in children from a community-based cohort and in hospitalized children, (2) assess the clinical features of illnesses with different HCoV types detected, and (3) evaluate potential risk factors associated with increased severity of illness, defined as the use of respiratory support and/or hospitalization in the pediatric intensive care unit (PICU). To evaluate potential risk factors associated with increased severity of illness in the hospitalized children with HCoV, demographic (eg, age, sex) and clinical characteristics (ie, chronic complex conditions [CCCs]), HCoV types and viral coinfection associated with respiratory support (defined above), and/ or PICU admissions were collected from the electronic medical record. Among hospitalized children, bivariate analyses assessed the associations of demographic characteristics, clinical factors, HCoV types, and presence of viral codetections, with increased severity of illness, ie, receiving respiratory support and/or admission to the PICU. ./cache/cord-263688-xz2hnym0.txt ./txt/cord-263688-xz2hnym0.txt