id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-269266-ygewa5xd	Wurzel, Danielle F.	Adenovirus Species C Is Associated With Chronic Suppurative Lung Diseases in Children	2014-04-18		.txt	text/plain	4370	228	44	An HAdV(+) BAL was significantly associated with bacterial coinfection with Haemophilus influenzae, Moraxella catarrhalis, or Streptococcus pneumoniae (odds ratio [OR], 3.27; 95% confidence interval, 1.38–7.75; P = .007) and negatively associated with Staphylococcus aureus infection (P = .03). Human adenovirus (HAdV) detection is associated with lower airway neutrophilic inflammation in children with chronic respiratory symptoms, [13] and is significantly more likely to be present in the lower airways of children with PBB, compared with controls [14] . We hypothesized that, in the lower airways of children with PBB and mild BE, certain HAdV genotypes/species would predominate, and that presence of HAdV increases the risk of bacterial coinfection. This is the first study to examine the HAdV genotypes detectable in the lower airways of children with chronic endobronchial suppuration (PBB and bronchiectasis). The significant association between HAdV and lower airway bacterial infection suggests a possible role of HAdV-C in the pathogenesis of chronic suppurative lung diseases in young children.	./cache/cord-269266-ygewa5xd.txt	./txt/cord-269266-ygewa5xd.txt