id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-273620-gn8g6suq	Szczawinska‐Poplonyk, Aleksandra	Fatal respiratory distress syndrome due to coronavirus infection in a child with severe combined immunodeficiency	2012-11-30		.txt	text/plain	1447	80	36	2 Human coronaviruses (HCoV) HCoV-229E and HCoV-OC43 and related new strains HCoV-NL63 and HCoV-HKU1, identified after the epidemic outbreak of severe acquired respiratory syndrome (SARS) coronavirus, are likely to be common respiratory viruses in otherwise healthy children and were not implicated in severe lung infections in immunocompromised patients thus far. The chest X-ray of a 15-month-old child with severe combined immunodeficiency and respiratory distress syndrome due to coronavirus HKU1 infection. However, it is worth noting that coronavirus respiratory infections have not been described in children with genetically determined immunodeficiencies thus far and this is the first report of a documented HCoV-HKU1-related pneumonia with the RDS in a child with SCID. The identification of HCoV-HKU1 provides a novel insight into the epidemiology and clinical implications of coronavirus infections in severely immunocompromised children and indicates for consideration of this pathogen-related etiology of respiratory infection in SCID.	./cache/cord-273620-gn8g6suq.txt	./txt/cord-273620-gn8g6suq.txt