id author title date pages extension mime words sentences flesch summary cache txt cord-277805-b3hizdmz Catassi, Giulia N. A negative fallout of COVID-19 lockdown in Italy: life-threatening delay in the diagnosis of celiac disease 2020-05-16 .txt text/plain 1049 64 48 On COVID-19 day-19 lockdown in Italy (March 31, 2020), a 17-month-old girl presented at our pediatric academic medical center for evaluation of abdominal pain and distention, and widespread edema. Since the clinical history suggested celiac disease (CD), serum CD autoantibodies were checked, as recommended by the European Society for Pediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN) diagnostic guidelines, 1 and a gluten-free diet (GFD) was started before getting the results, due to the severity of symptoms. In young children, delayed CD diagnosis may be responsible for life-threatening manifestations, such as the celiac crisis and intestinal intussusception observed in our patient. 1 In conclusion, the history of this patient highlights a potentially life-threatening delay in the diagnosis and treatment of CD, a disorder usually characterized by a benign presentation in Europe, that was apparently related to the negative impact of COVID-19 lockdown on clinical practice in Italy. ./cache/cord-277805-b3hizdmz.txt ./txt/cord-277805-b3hizdmz.txt