id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-283138-18q23z8l	Balasubramanian, S.	Coronavirus Disease 2019 (COVID-19) in Children - What We Know So Far and What We Do Not	2020-04-09		.txt	text/plain	3464	205	44	Pediatric coronavirus disease-19 (COVID-19) infection is relatively mild when compared to adults, and children are reported to have a better prognosis. Clinical features of COVID-19 in children include fever and cough, but a large proportion of infected children appears to be asymptomatic and may contribute to transmission. It remains unclear why children and young adults are less severely affected than older individuals, but this might involve differences in immune system function in the elderly and/or differences in the expression/function of the cellular receptor for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)Angiotensin converting enzyme 2 (ACE2). This review additionally considers COVID-19 in immunosuppressed children, and also suggests a management algorithm for the few children who appear to present with life threatening infection, including the potential use of antiviral and immunomodulatory treatment. Asymptomatic, mild and moderate infections comprise over 90% of all children who have tested positive for COVID-19 with fewer severe and critical cases (5.9%) compared to adults (18.5%) [13] .	./cache/cord-283138-18q23z8l.txt	./txt/cord-283138-18q23z8l.txt