id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-304437-ezqghyid	Palmieri, Tina L.	Children are not little adults: blood transfusion in children with burn injury	2017-08-15		.txt	text/plain	3886	218	46	Children in particular have a different physiology than adults, which needs to be considered prior to transfusing blood and blood products. This article describes the physiologic differences between children and adults in general and after burn injury and describes how these differences impact blood transfusion practices in children. This article will discuss how differences in the physiologic, hematologic, metabolic, and immunologic systems in burned children impact blood transfusion requirements. Hyperkalemia has been associated with cardiac arrest during large blood volume transfusions intraoperatively in children and infants receiving exchange transfusions [9, 10] . 2. Cardiac function, mean blood volume, and normal hemoglobin levels are age-dependent in children; hence, children have a higher blood transfusion/unit volume ratio. Transfusion-related graft-versus-host reaction, in which the lymphocytes in the transfused blood cause host cell destruction, occurs primarily in immunocompromised patients and has been reported in neonates and immunocompromised children [25] [26] [27] [28] .	./cache/cord-304437-ezqghyid.txt	./txt/cord-304437-ezqghyid.txt