id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-322575-3goj00ej	Karl, Julie A.	Major Histocompatibility Complex Class I Haplotype Diversity in Chinese Rhesus Macaques	2013-07-01		.txt	text/plain	4447	210	49	The use of Chinese-origin rhesus macaques (Macaca mulatta) for infectious disease immunity research is increasing despite the relative lack of major histocompatibility complex (MHC) class I immunogenetics information available for this population. We determined transcript-based MHC class I haplotypes for 385 Chinese rhesus macaques from five different experimental cohorts, providing a concise representation of the full complement of MHC class I major alleles expressed by each animal. Our group and others have shown that the repertoire of MHC class I alleles expressed by Chinese rhesus macaques is largely distinct from that observed in Indian rhesus macaques (Otting et al. We also compared our 139 Chinese-and Indian-origin rhesus macaque haplotypes against the well-characterized panel of Mauritian cynomolgus macaque (Macaca fascicularis; Mafa) haplotypes to explore possible ancestral haplotype sharing between the two species (Wiseman et al. However, our model of defining MHC class I haplotypes of coinherited highly expressed major alleles provides a novel approach for assessing putatively functional similarities between macaque populations.	./cache/cord-322575-3goj00ej.txt	./txt/cord-322575-3goj00ej.txt