id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-001687-paax8pqh	Henkel, Jan	Bone Regeneration Based on Tissue Engineering Conceptions — A 21st Century Perspective	2013-09-25		.txt	text/plain	15788	674	35	Engineering functional bone using combinations of cells, scaffolds and bioactive factors is a promising strategy and a particular feature for future development in the area of hybrid materials which are able to exhibit suitable biomimetic and mechanical properties. Engineering functional bone using combinations of cells, scaffolds and bioactive factors are seen as a promising approach and these techniques will undoubtedly lead to ceaseless possibilities for tissue regeneration and repair. According to the "diamond concept" of bone tissue engineering (77) (78) , an ideal bone substitute material should offer an osteoinductive three-dimensional structure, contain osteogenic cells and osteoinductive factors, have sufficient mechanical properties and promote vascularisation. As reviewed in detail in Reference (200) , we were able to demonstrate the in vivo capability of our composite scaffolds in combination with growth factors or cells to promote bone regeneration within ectopic sites or critical sized cranial defects in the small animal models.	./cache/cord-001687-paax8pqh.txt	./txt/cord-001687-paax8pqh.txt