id author title date pages extension mime words sentences flesch summary cache txt cord-260993-udajtsmm Youssef, Mohanad COVID‐19 and Liver Dysfunction: a systematic review and meta‐analysis of retrospective studies 2020-05-23 .txt text/plain 2056 148 49 Meta-regression analysis was employed using OpenMeta Analyst software, taking into consideration the following study characteristics; sample size, mean age of patients, percentage of males, city of the hospital, publication date, and quality score. We applied TSA on mortality rate available among all eligible articles of COVID-19 patients with a mild and severe exhibition and indicated that the cumulative Z-curve transverses the monitoring boundaries before reaching the required sample size and achieving considerable significant and so no further studies are necessary (Figure 2 ). Our meta-analysis including 3428 subjects from 20 retrospective studies explored the potential relationship between liver injury and the severity of COVID-19 disease. 32 A recent study reported that the liver injury observed in COVID-19 patients might be caused by lopinavir, which is used as an antiviral for the treatment of SARS-CoV-2 infection. In this meta-analysis, we comprehensively analyzed liver dysfunction in accordance with the severity of clinical outcomes in COVID-19 patients. ./cache/cord-260993-udajtsmm.txt ./txt/cord-260993-udajtsmm.txt