id author title date pages extension mime words sentences flesch summary cache txt cord-276495-q22jnkn2 Belizário, José Ernesto Trained innate immunity, COVID-19 therapeutic dilemma, and fake science 2020-07-06 .txt text/plain 2769 132 44 This type of immunological memory or epigenetic programming to a pre-activated state allows the generation of a sustained and more effective non-specific response, even after years, although in the protocols of these studies, the innate immunity was evaluated after 3 months (2). Various clinical trials are underway to evaluate trained immunity through BCG vaccination in healthy volunteers under the coordination of Dr. Mihail Netea (Radboud University Medical Center, Nijmegen, the Netherlands). To our knowledge, there are no published articles or clinical evidences that show that BCG immunization protects against SARS-CoV-2 in Brazil. The journal The Lancet, in May 2020, published the results of an observational, longitudinal, and retrospective clinical study based on medical records of COVID-19 patient cohorts treated across 6 countries and 671 hospitals, with different technical capabilities and diverse drug protocols (13) . ./cache/cord-276495-q22jnkn2.txt ./txt/cord-276495-q22jnkn2.txt