id author title date pages extension mime words sentences flesch summary cache txt cord-354216-4khdcjed Sultan, Shahnaz AGA Institute Rapid Review of the GI and Liver Manifestations of COVID-19, Meta-Analysis of International Data, and Recommendations for the Consultative Management of Patients with COVID-19 2020-05-11 .txt text/plain 5641 336 45 Abstract Background Multiple gastrointestinal (GI) symptoms including diarrhea, nausea/vomiting, and abdominal pain, as well liver enzyme abnormalities have been variably reported in patients with COVID-19. The AGA) Institute Clinical Guideline Committee and Clinical Practice Updates Committee performed a systematic review and meta-analysis of international data on GI and liver manifestations of COVID-19. 4 More recent data from a cohort of 5700 hospitalized patients with COVID-19 within a large healthcare system in New York City revealed common comorbidities including hypertension (56.6%), obesity (41.7%), and diabetes (33.8%), and reported that 373 (14.2%) of patients required treatment in the intensive care unit, and 320 (12.2%) received invasive mechanical ventilation, in whom the mortality was 88.1% (282/320)]. Also, many of the studies in this analysis did not report on how many patients had underlying liver disease and if these patients were at an elevated risk of having increased LFTs in the setting of COVID-19 infection. ./cache/cord-354216-4khdcjed.txt ./txt/cord-354216-4khdcjed.txt