id	sid	tid	token	lemma	pos
cord-021494-9glqvzfx	1	1	key	key	NN
cord-021494-9glqvzfx	1	2	:	:	:
cord-021494-9glqvzfx	2	1	cord-021494	cord-021494	NNP
cord-021494-9glqvzfx	2	2	-	-	HYPH
cord-021494-9glqvzfx	2	3	9glqvzfx	9glqvzfx	CD
cord-021494-9glqvzfx	2	4	authors	author	NNS
cord-021494-9glqvzfx	2	5	:	:	:
cord-021494-9glqvzfx	2	6	Funkhouser	Funkhouser	NNP
cord-021494-9glqvzfx	2	7	,	,	,
cord-021494-9glqvzfx	2	8	William	William	NNP
cord-021494-9glqvzfx	2	9	K.	K.	NNP
cord-021494-9glqvzfx	2	10	title	title	NN
cord-021494-9glqvzfx	2	11	:	:	:
cord-021494-9glqvzfx	2	12	Pathology	pathology	NN
cord-021494-9glqvzfx	2	13	:	:	:
cord-021494-9glqvzfx	2	14	The	the	DT
cord-021494-9glqvzfx	2	15	Clinical	clinical	JJ
cord-021494-9glqvzfx	2	16	Description	description	NN
cord-021494-9glqvzfx	2	17	of	of	IN
cord-021494-9glqvzfx	2	18	Human	Human	NNP
cord-021494-9glqvzfx	2	19	Disease	Disease	NNP
cord-021494-9glqvzfx	2	20	date	date	NN
cord-021494-9glqvzfx	2	21	:	:	:
cord-021494-9glqvzfx	2	22	2012	2012	CD
cord-021494-9glqvzfx	2	23	-	-	HYPH
cord-021494-9glqvzfx	2	24	07	07	CD
cord-021494-9glqvzfx	2	25	-	-	HYPH
cord-021494-9glqvzfx	2	26	27	27	CD
cord-021494-9glqvzfx	2	27	journal	journal	NN
cord-021494-9glqvzfx	2	28	:	:	:
cord-021494-9glqvzfx	2	29	Essential	essential	JJ
cord-021494-9glqvzfx	2	30	Concepts	Concepts	NNPS
cord-021494-9glqvzfx	2	31	in	in	IN
cord-021494-9glqvzfx	2	32	Molecular	Molecular	NNP
cord-021494-9glqvzfx	2	33	Pathology	Pathology	NNP
cord-021494-9glqvzfx	3	1	DOI	DOI	NNP
cord-021494-9glqvzfx	3	2	:	:	:
cord-021494-9glqvzfx	4	1	10.1016	10.1016	CD
cord-021494-9glqvzfx	4	2	/	/	SYM
cord-021494-9glqvzfx	4	3	b978	b978	NN
cord-021494-9glqvzfx	4	4	-	-	HYPH
cord-021494-9glqvzfx	4	5	0	0	CD
cord-021494-9glqvzfx	4	6	-	-	HYPH
cord-021494-9glqvzfx	4	7	12	12	CD
cord-021494-9glqvzfx	4	8	-	-	HYPH
cord-021494-9glqvzfx	4	9	374418	374418	CD
cord-021494-9glqvzfx	4	10	-	-	HYPH
cord-021494-9glqvzfx	4	11	0.00011	0.00011	CD
cord-021494-9glqvzfx	4	12	-	-	SYM
cord-021494-9glqvzfx	4	13	6	6	CD
cord-021494-9glqvzfx	4	14	sha	sha	NN
cord-021494-9glqvzfx	4	15	:	:	:
cord-021494-9glqvzfx	4	16	099e33eacfad2024c1c3bb0b1664f86a27c9882a	099e33eacfad2024c1c3bb0b1664f86a27c9882a	CD
cord-021494-9glqvzfx	4	17	doc_id	doc_id	CD
cord-021494-9glqvzfx	4	18	:	:	:
cord-021494-9glqvzfx	4	19	21494	21494	CD
cord-021494-9glqvzfx	4	20	cord_uid	cord_uid	NNS
cord-021494-9glqvzfx	4	21	:	:	:
cord-021494-9glqvzfx	5	1	9glqvzfx	9glqvzfx	CD
cord-021494-9glqvzfx	5	2	nan	nan	NNP
cord-021494-9glqvzfx	5	3	radiographic	radiographic	JJ
cord-021494-9glqvzfx	5	4	examination	examination	NN
cord-021494-9glqvzfx	5	5	,	,	,
cord-021494-9glqvzfx	5	6	fluid	fluid	JJ
cord-021494-9glqvzfx	5	7	tests	test	NNS
cord-021494-9glqvzfx	5	8	(	(	-LRB-
cord-021494-9glqvzfx	5	9	blood	blood	NN
cord-021494-9glqvzfx	5	10	,	,	,
cord-021494-9glqvzfx	5	11	urine	urine	NN
cord-021494-9glqvzfx	5	12	,	,	,
cord-021494-9glqvzfx	5	13	sputum	sputum	NN
cord-021494-9glqvzfx	5	14	,	,	,
cord-021494-9glqvzfx	5	15	stool	stool	NN
cord-021494-9glqvzfx	5	16	)	)	-RRB-
cord-021494-9glqvzfx	5	17	,	,	,
cord-021494-9glqvzfx	5	18	and	and	CC
cord-021494-9glqvzfx	5	19	possibly	possibly	RB
cord-021494-9glqvzfx	5	20	tissue	tissue	VB
cord-021494-9glqvzfx	5	21	biopsy	biopsy	NN
cord-021494-9glqvzfx	5	22	.	.	.
cord-021494-9glqvzfx	6	1	Radiographically	radiographically	RB
cord-021494-9glqvzfx	6	2	,	,	,
cord-021494-9glqvzfx	6	3	abnormalities	abnormality	NNS
cord-021494-9glqvzfx	6	4	in	in	IN
cord-021494-9glqvzfx	6	5	abundance	abundance	NN
cord-021494-9glqvzfx	6	6	,	,	,
cord-021494-9glqvzfx	6	7	density	density	NN
cord-021494-9glqvzfx	6	8	or	or	CC
cord-021494-9glqvzfx	6	9	chemical	chemical	JJ
cord-021494-9glqvzfx	6	10	microenvironment	microenvironment	NN
cord-021494-9glqvzfx	6	11	of	of	IN
cord-021494-9glqvzfx	6	12	tissues	tissue	NNS
cord-021494-9glqvzfx	6	13	allows	allow	VBZ
cord-021494-9glqvzfx	6	14	distinction	distinction	NN
cord-021494-9glqvzfx	6	15	from	from	IN
cord-021494-9glqvzfx	6	16	surrounding	surround	VBG
cord-021494-9glqvzfx	6	17	normal	normal	JJ
cord-021494-9glqvzfx	6	18	tissues	tissue	NNS
cord-021494-9glqvzfx	6	19	.	.	.
cord-021494-9glqvzfx	7	1	Traditionally	traditionally	RB
cord-021494-9glqvzfx	7	2	,	,	,
cord-021494-9glqvzfx	7	3	the	the	DT
cord-021494-9glqvzfx	7	4	absorption	absorption	NN
cord-021494-9glqvzfx	7	5	of	of	IN
cord-021494-9glqvzfx	7	6	electromagnetic	electromagnetic	JJ
cord-021494-9glqvzfx	7	7	waves	wave	NNS
cord-021494-9glqvzfx	7	8	by	by	IN
cord-021494-9glqvzfx	7	9	tissues	tissue	NNS
cord-021494-9glqvzfx	7	10	led	lead	VBD
cord-021494-9glqvzfx	7	11	to	to	IN
cord-021494-9glqvzfx	7	12	summation	summation	JJ
cord-021494-9glqvzfx	7	13	differences	difference	NNS
cord-021494-9glqvzfx	7	14	in	in	IN
cord-021494-9glqvzfx	7	15	exposure	exposure	NN
cord-021494-9glqvzfx	7	16	of	of	IN
cord-021494-9glqvzfx	7	17	silver	silver	NN
cord-021494-9glqvzfx	7	18	salt	salt	NN
cord-021494-9glqvzfx	7	19	photographic	photographic	JJ
cord-021494-9glqvzfx	7	20	film	film	NN
cord-021494-9glqvzfx	7	21	.	.	.
cord-021494-9glqvzfx	8	1	Tomographic	tomographic	JJ
cord-021494-9glqvzfx	8	2	approaches	approach	NNS
cord-021494-9glqvzfx	8	3	such	such	JJ
cord-021494-9glqvzfx	8	4	as	as	IN
cord-021494-9glqvzfx	8	5	CT	CT	NNP
cord-021494-9glqvzfx	8	6	(	(	-LRB-
cord-021494-9glqvzfx	8	7	1972	1972	CD
cord-021494-9glqvzfx	8	8	)	)	-RRB-
cord-021494-9glqvzfx	8	9	and	and	CC
cord-021494-9glqvzfx	8	10	NMR	NMR	NNP
cord-021494-9glqvzfx	8	11	(	(	-LRB-
cord-021494-9glqvzfx	8	12	1973	1973	CD
cord-021494-9glqvzfx	8	13	)	)	-RRB-
cord-021494-9glqvzfx	8	14	complemented	complement	VBD
cord-021494-9glqvzfx	8	15	summation	summation	JJ
cord-021494-9glqvzfx	8	16	radiology	radiology	NN
cord-021494-9glqvzfx	8	17	,	,	,
cord-021494-9glqvzfx	8	18	allowing	allow	VBG
cord-021494-9glqvzfx	8	19	finely	finely	RB
cord-021494-9glqvzfx	8	20	detailed	detailed	JJ
cord-021494-9glqvzfx	8	21	visualization	visualization	NN
cord-021494-9glqvzfx	8	22	of	of	IN
cord-021494-9glqvzfx	8	23	internal	internal	JJ
cord-021494-9glqvzfx	8	24	anatomy	anatomy	NN
cord-021494-9glqvzfx	8	25	in	in	IN
cord-021494-9glqvzfx	8	26	any	any	DT
cord-021494-9glqvzfx	8	27	plane	plane	NN
cord-021494-9glqvzfx	8	28	of	of	IN
cord-021494-9glqvzfx	8	29	section	section	NN
cord-021494-9glqvzfx	8	30	.	.	.
cord-021494-9glqvzfx	9	1	In	in	IN
cord-021494-9glqvzfx	9	2	the	the	DT
cord-021494-9glqvzfx	9	3	same	same	JJ
cord-021494-9glqvzfx	9	4	era	era	NN
cord-021494-9glqvzfx	9	5	,	,	,
cord-021494-9glqvzfx	9	6	ultrasound	ultrasound	NN
cord-021494-9glqvzfx	9	7	allowed	allow	VBD
cord-021494-9glqvzfx	9	8	visualization	visualization	NN
cord-021494-9glqvzfx	9	9	of	of	IN
cord-021494-9glqvzfx	9	10	tissue	tissue	NN
cord-021494-9glqvzfx	9	11	with	with	IN
cord-021494-9glqvzfx	9	12	density	density	NN
cord-021494-9glqvzfx	9	13	differences	difference	NNS
cord-021494-9glqvzfx	9	14	,	,	,
cord-021494-9glqvzfx	9	15	such	such	JJ
cord-021494-9glqvzfx	9	16	as	as	IN
cord-021494-9glqvzfx	9	17	a	a	DT
cord-021494-9glqvzfx	9	18	developing	develop	VBG
cord-021494-9glqvzfx	9	19	fetus	fetus	NN
cord-021494-9glqvzfx	9	20	or	or	CC
cord-021494-9glqvzfx	9	21	gallbladder	gallbladder	NN
cord-021494-9glqvzfx	9	22	stones	stone	NNS
cord-021494-9glqvzfx	9	23	.	.	.
cord-021494-9glqvzfx	10	1	More	more	RBR
cord-021494-9glqvzfx	10	2	recently	recently	RB
cord-021494-9glqvzfx	10	3	,	,	,
cord-021494-9glqvzfx	10	4	physiology	physiology	NN
cord-021494-9glqvzfx	10	5	of	of	IN
cord-021494-9glqvzfx	10	6	neoplasms	neoplasm	NNS
cord-021494-9glqvzfx	10	7	can	can	MD
cord-021494-9glqvzfx	10	8	be	be	VB
cord-021494-9glqvzfx	10	9	screened	screen	VBN
cord-021494-9glqvzfx	10	10	with	with	IN
cord-021494-9glqvzfx	10	11	positron	positron	NN
cord-021494-9glqvzfx	10	12	emission	emission	NN
cord-021494-9glqvzfx	10	13	tomography	tomography	NN
cord-021494-9glqvzfx	10	14	(	(	-LRB-
cord-021494-9glqvzfx	10	15	PET	pet	NN
cord-021494-9glqvzfx	10	16	,	,	,
cord-021494-9glqvzfx	10	17	1977	1977	CD
cord-021494-9glqvzfx	10	18	)	)	-RRB-
cord-021494-9glqvzfx	10	19	for	for	IN
cord-021494-9glqvzfx	10	20	decay	decay	NN
cord-021494-9glqvzfx	10	21	of	of	IN
cord-021494-9glqvzfx	10	22	short	short	JJ
cord-021494-9glqvzfx	10	23	half	half	JJ
cord-021494-9glqvzfx	10	24	-	-	HYPH
cord-021494-9glqvzfx	10	25	life	life	NN
cord-021494-9glqvzfx	10	26	isotopes	isotope	NNS
cord-021494-9glqvzfx	10	27	such	such	JJ
cord-021494-9glqvzfx	10	28	as	as	IN
cord-021494-9glqvzfx	10	29	fluorodeoxyglucose	fluorodeoxyglucose	JJ
cord-021494-9glqvzfx	10	30	.	.	.
cord-021494-9glqvzfx	11	1	Neoplasms	neoplasm	NNS
cord-021494-9glqvzfx	11	2	with	with	IN
cord-021494-9glqvzfx	11	3	high	high	JJ
cord-021494-9glqvzfx	11	4	metabolism	metabolism	NN
cord-021494-9glqvzfx	11	5	can	can	MD
cord-021494-9glqvzfx	11	6	be	be	VB
cord-021494-9glqvzfx	11	7	distinguished	distinguish	VBN
cord-021494-9glqvzfx	11	8	physiologically	physiologically	RB
cord-021494-9glqvzfx	11	9	from	from	IN
cord-021494-9glqvzfx	11	10	adjacent	adjacent	JJ
cord-021494-9glqvzfx	11	11	low	low	JJ
cord-021494-9glqvzfx	11	12	-	-	HYPH
cord-021494-9glqvzfx	11	13	metabolism	metabolism	NN
cord-021494-9glqvzfx	11	14	tissues	tissue	NNS
cord-021494-9glqvzfx	11	15	,	,	,
cord-021494-9glqvzfx	11	16	and	and	CC
cord-021494-9glqvzfx	11	17	can	can	MD
cord-021494-9glqvzfx	11	18	be	be	VB
cord-021494-9glqvzfx	11	19	localized	localize	VBN
cord-021494-9glqvzfx	11	20	with	with	IN
cord-021494-9glqvzfx	11	21	respect	respect	NN
cord-021494-9glqvzfx	11	22	to	to	IN
cord-021494-9glqvzfx	11	23	normal	normal	JJ
cord-021494-9glqvzfx	11	24	tissues	tissue	NNS
cord-021494-9glqvzfx	11	25	by	by	IN
cord-021494-9glqvzfx	11	26	pairing	pair	VBG
cord-021494-9glqvzfx	11	27	PET	pet	NN
cord-021494-9glqvzfx	11	28	with	with	IN
cord-021494-9glqvzfx	11	29	standard	standard	JJ
cord-021494-9glqvzfx	11	30	CT	CT	NNP
cord-021494-9glqvzfx	11	31	.	.	.
cord-021494-9glqvzfx	12	1	The	the	DT
cord-021494-9glqvzfx	12	2	result	result	NN
cord-021494-9glqvzfx	12	3	is	be	VBZ
cord-021494-9glqvzfx	12	4	an	an	DT
cord-021494-9glqvzfx	12	5	astonishingly	astonishingly	RB
cord-021494-9glqvzfx	12	6	useful	useful	JJ
cord-021494-9glqvzfx	12	7	means	mean	NNS
cord-021494-9glqvzfx	12	8	of	of	IN
cord-021494-9glqvzfx	12	9	identifying	identify	VBG
cord-021494-9glqvzfx	12	10	and	and	CC
cord-021494-9glqvzfx	12	11	localizing	localize	VBG
cord-021494-9glqvzfx	12	12	new	new	JJ
cord-021494-9glqvzfx	12	13	space	space	NN
cord-021494-9glqvzfx	12	14	-	-	HYPH
cord-021494-9glqvzfx	12	15	occupying	occupy	VBG
cord-021494-9glqvzfx	12	16	masses	masse	NNS
cord-021494-9glqvzfx	12	17	,	,	,
cord-021494-9glqvzfx	12	18	assigning	assign	VBG
cord-021494-9glqvzfx	12	19	a	a	DT
cord-021494-9glqvzfx	12	20	risk	risk	NN
cord-021494-9glqvzfx	12	21	for	for	IN
cord-021494-9glqvzfx	12	22	malignant	malignant	JJ
cord-021494-9glqvzfx	12	23	behavior	behavior	NN
cord-021494-9glqvzfx	12	24	and	and	CC
cord-021494-9glqvzfx	12	25	,	,	,
cord-021494-9glqvzfx	12	26	if	if	IN
cord-021494-9glqvzfx	12	27	malignant	malignant	JJ
cord-021494-9glqvzfx	12	28	,	,	,
cord-021494-9glqvzfx	12	29	screening	screen	VBG
cord-021494-9glqvzfx	12	30	for	for	IN
cord-021494-9glqvzfx	12	31	metastases	metastasis	NNS
cord-021494-9glqvzfx	12	32	in	in	IN
cord-021494-9glqvzfx	12	33	distant	distant	JJ
cord-021494-9glqvzfx	12	34	sites	site	NNS
cord-021494-9glqvzfx	12	35	.	.	.
cord-021494-9glqvzfx	13	1	This	this	DT
cord-021494-9glqvzfx	13	2	technique	technique	NN
cord-021494-9glqvzfx	13	3	is	be	VBZ
cord-021494-9glqvzfx	13	4	revolutionizing	revolutionize	VBG
cord-021494-9glqvzfx	13	5	the	the	DT
cord-021494-9glqvzfx	13	6	preoperative	preoperative	JJ
cord-021494-9glqvzfx	13	7	decisionmaking	decisionmaking	NN
cord-021494-9glqvzfx	13	8	of	of	IN
cord-021494-9glqvzfx	13	9	clinical	clinical	JJ
cord-021494-9glqvzfx	13	10	teams	team	NNS
cord-021494-9glqvzfx	13	11	,	,	,
cord-021494-9glqvzfx	13	12	and	and	CC
cord-021494-9glqvzfx	13	13	improves	improve	VBZ
cord-021494-9glqvzfx	13	14	the	the	DT
cord-021494-9glqvzfx	13	15	likelihood	likelihood	NN
cord-021494-9glqvzfx	13	16	that	that	IN
cord-021494-9glqvzfx	13	17	patients	patient	NNS
cord-021494-9glqvzfx	13	18	undergo	undergo	VBP
cord-021494-9glqvzfx	13	19	resections	resection	NNS
cord-021494-9glqvzfx	13	20	of	of	IN
cord-021494-9glqvzfx	13	21	new	new	JJ
cord-021494-9glqvzfx	13	22	mass	mass	JJ
cord-021494-9glqvzfx	13	23	lesions	lesion	NNS
cord-021494-9glqvzfx	13	24	only	only	RB
cord-021494-9glqvzfx	13	25	when	when	WRB
cord-021494-9glqvzfx	13	26	at	at	IN
cord-021494-9glqvzfx	13	27	risk	risk	NN
cord-021494-9glqvzfx	13	28	for	for	IN
cord-021494-9glqvzfx	13	29	morbidity	morbidity	NN
cord-021494-9glqvzfx	13	30	from	from	IN
cord-021494-9glqvzfx	13	31	malignant	malignant	JJ
cord-021494-9glqvzfx	13	32	behavior	behavior	NN
cord-021494-9glqvzfx	13	33	or	or	CC
cord-021494-9glqvzfx	13	34	interference	interference	NN
cord-021494-9glqvzfx	13	35	with	with	IN
cord-021494-9glqvzfx	13	36	normal	normal	JJ
cord-021494-9glqvzfx	13	37	function	function	NN
cord-021494-9glqvzfx	13	38	.	.	.
cord-021494-9glqvzfx	14	1	Pathologically	pathologically	RB
cord-021494-9glqvzfx	14	2	,	,	,
cord-021494-9glqvzfx	14	3	disease	disease	NN
cord-021494-9glqvzfx	14	4	is	be	VBZ
cord-021494-9glqvzfx	14	5	diagnosed	diagnose	VBN
cord-021494-9glqvzfx	14	6	by	by	IN
cord-021494-9glqvzfx	14	7	determining	determine	VBG
cord-021494-9glqvzfx	14	8	whether	whether	IN
cord-021494-9glqvzfx	14	9	the	the	DT
cord-021494-9glqvzfx	14	10	morphologic	morphologic	JJ
cord-021494-9glqvzfx	14	11	features	feature	NNS
cord-021494-9glqvzfx	14	12	match	match	VBP
cord-021494-9glqvzfx	14	13	the	the	DT
cord-021494-9glqvzfx	14	14	set	set	NN
cord-021494-9glqvzfx	14	15	of	of	IN
cord-021494-9glqvzfx	14	16	diagnostic	diagnostic	JJ
cord-021494-9glqvzfx	14	17	criteria	criterion	NNS
cord-021494-9glqvzfx	14	18	previously	previously	RB
cord-021494-9glqvzfx	14	19	described	describe	VBN
cord-021494-9glqvzfx	14	20	for	for	IN
cord-021494-9glqvzfx	14	21	each	each	DT
cord-021494-9glqvzfx	14	22	disease	disease	NN
cord-021494-9glqvzfx	14	23	.	.	.
cord-021494-9glqvzfx	15	1	Multivolume	multivolume	JJ
cord-021494-9glqvzfx	15	2	texts	text	NNS
cord-021494-9glqvzfx	15	3	are	be	VBP
cord-021494-9glqvzfx	15	4	devoted	devoted	JJ
cord-021494-9glqvzfx	15	5	to	to	IN
cord-021494-9glqvzfx	15	6	the	the	DT
cord-021494-9glqvzfx	15	7	gross	gross	JJ
cord-021494-9glqvzfx	15	8	and	and	CC
cord-021494-9glqvzfx	15	9	microscopic	microscopic	JJ
cord-021494-9glqvzfx	15	10	diagnostic	diagnostic	JJ
cord-021494-9glqvzfx	15	11	criteria	criterion	NNS
cord-021494-9glqvzfx	15	12	used	use	VBN
cord-021494-9glqvzfx	15	13	for	for	IN
cord-021494-9glqvzfx	15	14	diagnosis	diagnosis	NN
cord-021494-9glqvzfx	15	15	,	,	,
cord-021494-9glqvzfx	15	16	prognosis	prognosis	NN
cord-021494-9glqvzfx	15	17	,	,	,
cord-021494-9glqvzfx	15	18	and	and	CC
cord-021494-9glqvzfx	15	19	prediction	prediction	NN
cord-021494-9glqvzfx	15	20	of	of	IN
cord-021494-9glqvzfx	15	21	response	response	NN
cord-021494-9glqvzfx	15	22	to	to	IN
cord-021494-9glqvzfx	15	23	therapy	therapy	NN
cord-021494-9glqvzfx	15	24	.	.	.
cord-021494-9glqvzfx	16	1	Pathologists	pathologist	NNS
cord-021494-9glqvzfx	16	2	diagnose	diagnose	VBP
cord-021494-9glqvzfx	16	3	disease	disease	NN
cord-021494-9glqvzfx	16	4	by	by	IN
cord-021494-9glqvzfx	16	5	generating	generate	VBG
cord-021494-9glqvzfx	16	6	a	a	DT
cord-021494-9glqvzfx	16	7	differential	differential	JJ
cord-021494-9glqvzfx	16	8	diagnosis	diagnosis	NN
cord-021494-9glqvzfx	16	9	,	,	,
cord-021494-9glqvzfx	16	10	then	then	RB
cord-021494-9glqvzfx	16	11	finding	find	VBG
cord-021494-9glqvzfx	16	12	the	the	DT
cord-021494-9glqvzfx	16	13	best	good	JJS
cord-021494-9glqvzfx	16	14	fit	fit	NN
cord-021494-9glqvzfx	16	15	for	for	IN
cord-021494-9glqvzfx	16	16	the	the	DT
cord-021494-9glqvzfx	16	17	clinical	clinical	JJ
cord-021494-9glqvzfx	16	18	presentation	presentation	NN
cord-021494-9glqvzfx	16	19	,	,	,
cord-021494-9glqvzfx	16	20	the	the	DT
cord-021494-9glqvzfx	16	21	radiographic	radiographic	JJ
cord-021494-9glqvzfx	16	22	appearance	appearance	NN
cord-021494-9glqvzfx	16	23	,	,	,
cord-021494-9glqvzfx	16	24	and	and	CC
cord-021494-9glqvzfx	16	25	the	the	DT
cord-021494-9glqvzfx	16	26	pathologic	pathologic	JJ
cord-021494-9glqvzfx	16	27	(	(	-LRB-
cord-021494-9glqvzfx	16	28	both	both	DT
cord-021494-9glqvzfx	16	29	clinical	clinical	JJ
cord-021494-9glqvzfx	16	30	lab	lab	NN
cord-021494-9glqvzfx	16	31	and	and	CC
cord-021494-9glqvzfx	16	32	morphologic	morphologic	JJ
cord-021494-9glqvzfx	16	33	)	)	-RRB-
cord-021494-9glqvzfx	16	34	findings	finding	NNS
cord-021494-9glqvzfx	16	35	.	.	.
cord-021494-9glqvzfx	17	1	Logically	logically	RB
cord-021494-9glqvzfx	17	2	,	,	,
cord-021494-9glqvzfx	17	3	the	the	DT
cord-021494-9glqvzfx	17	4	Venn	Venn	NNP
cord-021494-9glqvzfx	17	5	diagram	diagram	NN
cord-021494-9glqvzfx	17	6	of	of	IN
cord-021494-9glqvzfx	17	7	the	the	DT
cord-021494-9glqvzfx	17	8	clinical	clinical	JJ
cord-021494-9glqvzfx	17	9	,	,	,
cord-021494-9glqvzfx	17	10	radiologic	radiologic	JJ
cord-021494-9glqvzfx	17	11	,	,	,
cord-021494-9glqvzfx	17	12	and	and	CC
cord-021494-9glqvzfx	17	13	pathologic	pathologic	JJ
cord-021494-9glqvzfx	17	14	differential	differential	JJ
cord-021494-9glqvzfx	17	15	diagnoses	diagnosis	NNS
cord-021494-9glqvzfx	17	16	should	should	MD
cord-021494-9glqvzfx	17	17	overlap	overlap	VB
cord-021494-9glqvzfx	17	18	.	.	.
cord-021494-9glqvzfx	18	1	Unexpected	unexpected	JJ
cord-021494-9glqvzfx	18	2	features	feature	NNS
cord-021494-9glqvzfx	18	3	expand	expand	VBP
cord-021494-9glqvzfx	18	4	the	the	DT
cord-021494-9glqvzfx	18	5	differential	differential	JJ
cord-021494-9glqvzfx	18	6	diagnosis	diagnosis	NN
cord-021494-9glqvzfx	18	7	and	and	CC
cord-021494-9glqvzfx	18	8	may	may	MD
cord-021494-9glqvzfx	18	9	raise	raise	VB
cord-021494-9glqvzfx	18	10	the	the	DT
cord-021494-9glqvzfx	18	11	possibility	possibility	NN
cord-021494-9glqvzfx	18	12	of	of	IN
cord-021494-9glqvzfx	18	13	previously	previously	RB
cord-021494-9glqvzfx	18	14	undescribed	undescribed	JJ
cord-021494-9glqvzfx	18	15	diseases	disease	NNS
cord-021494-9glqvzfx	18	16	.	.	.
cord-021494-9glqvzfx	19	1	For	for	IN
cord-021494-9glqvzfx	19	2	example	example	NN
cord-021494-9glqvzfx	19	3	,	,	,
cord-021494-9glqvzfx	19	4	Legionnaire	Legionnaire	NNP
cord-021494-9glqvzfx	19	5	's	's	POS
cord-021494-9glqvzfx	19	6	disease	disease	NN
cord-021494-9glqvzfx	19	7	,	,	,
cord-021494-9glqvzfx	19	8	human	human	JJ
cord-021494-9glqvzfx	19	9	immunodeficiency	immunodeficiency	NN
cord-021494-9glqvzfx	19	10	virus	virus	NN
cord-021494-9glqvzfx	19	11	(	(	-LRB-
cord-021494-9glqvzfx	19	12	HIV	HIV	NNP
cord-021494-9glqvzfx	19	13	)	)	-RRB-
cord-021494-9glqvzfx	19	14	,	,	,
cord-021494-9glqvzfx	19	15	Hantavirus	Hantavirus	NNP
cord-021494-9glqvzfx	19	16	pneumonia	pneumonia	NN
cord-021494-9glqvzfx	19	17	,	,	,
cord-021494-9glqvzfx	19	18	and	and	CC
cord-021494-9glqvzfx	19	19	severe	severe	JJ
cord-021494-9glqvzfx	19	20	acute	acute	JJ
cord-021494-9glqvzfx	19	21	respiratory	respiratory	JJ
cord-021494-9glqvzfx	19	22	syndrome	syndrome	NN
cord-021494-9glqvzfx	19	23	(	(	-LRB-
cord-021494-9glqvzfx	19	24	SARS	SARS	NNP
cord-021494-9glqvzfx	19	25	)	)	-RRB-
cord-021494-9glqvzfx	19	26	are	be	VBP
cord-021494-9glqvzfx	19	27	examples	example	NNS
cord-021494-9glqvzfx	19	28	of	of	IN
cord-021494-9glqvzfx	19	29	newly	newly	RB
cord-021494-9glqvzfx	19	30	described	describe	VBN
cord-021494-9glqvzfx	19	31	diagnoses	diagnosis	NNS
cord-021494-9glqvzfx	19	32	during	during	IN
cord-021494-9glqvzfx	19	33	the	the	DT
cord-021494-9glqvzfx	19	34	last	last	JJ
cord-021494-9glqvzfx	19	35	30	30	CD
cord-021494-9glqvzfx	19	36	years	year	NNS
cord-021494-9glqvzfx	19	37	.	.	.
cord-021494-9glqvzfx	20	1	The	the	DT
cord-021494-9glqvzfx	20	2	mental	mental	JJ
cord-021494-9glqvzfx	20	3	construct	construct	NN
cord-021494-9glqvzfx	20	4	of	of	IN
cord-021494-9glqvzfx	20	5	etiology	etiology	NN
cord-021494-9glqvzfx	20	6	(	(	-LRB-
cord-021494-9glqvzfx	20	7	cause	cause	NN
cord-021494-9glqvzfx	20	8	)	)	-RRB-
cord-021494-9glqvzfx	20	9	,	,	,
cord-021494-9glqvzfx	20	10	pathogenesis	pathogenesis	NN
cord-021494-9glqvzfx	20	11	(	(	-LRB-
cord-021494-9glqvzfx	20	12	progression	progression	NN
cord-021494-9glqvzfx	20	13	)	)	-RRB-
cord-021494-9glqvzfx	20	14	,	,	,
cord-021494-9glqvzfx	20	15	natural	natural	JJ
cord-021494-9glqvzfx	20	16	history	history	NN
cord-021494-9glqvzfx	20	17	(	(	-LRB-
cord-021494-9glqvzfx	20	18	clinical	clinical	JJ
cord-021494-9glqvzfx	20	19	outcome	outcome	NN
cord-021494-9glqvzfx	20	20	)	)	-RRB-
cord-021494-9glqvzfx	20	21	,	,	,
cord-021494-9glqvzfx	20	22	and	and	CC
cord-021494-9glqvzfx	20	23	response	response	NN
cord-021494-9glqvzfx	20	24	to	to	IN
cord-021494-9glqvzfx	20	25	therapy	therapy	NN
cord-021494-9glqvzfx	20	26	is	be	VBZ
cord-021494-9glqvzfx	20	27	the	the	DT
cord-021494-9glqvzfx	20	28	standard	standard	JJ
cord-021494-9glqvzfx	20	29	approach	approach	NN
cord-021494-9glqvzfx	20	30	for	for	IN
cord-021494-9glqvzfx	20	31	pathologists	pathologist	NNS
cord-021494-9glqvzfx	20	32	thinking	think	VBG
cord-021494-9glqvzfx	20	33	about	about	IN
cord-021494-9glqvzfx	20	34	a	a	DT
cord-021494-9glqvzfx	20	35	disease	disease	NN
cord-021494-9glqvzfx	20	36	.	.	.
cord-021494-9glqvzfx	21	1	A	a	DT
cord-021494-9glqvzfx	21	2	disease	disease	NN
cord-021494-9glqvzfx	21	3	may	may	MD
cord-021494-9glqvzfx	21	4	have	have	VB
cord-021494-9glqvzfx	21	5	one	one	CD
cord-021494-9glqvzfx	21	6	or	or	CC
cord-021494-9glqvzfx	21	7	more	more	JJR
cord-021494-9glqvzfx	21	8	etiologies	etiology	NNS
cord-021494-9glqvzfx	21	9	(	(	-LRB-
cord-021494-9glqvzfx	21	10	initial	initial	JJ
cord-021494-9glqvzfx	21	11	causes	cause	NNS
cord-021494-9glqvzfx	21	12	,	,	,
cord-021494-9glqvzfx	21	13	including	include	VBG
cord-021494-9glqvzfx	21	14	toxins	toxin	NNS
cord-021494-9glqvzfx	21	15	,	,	,
cord-021494-9glqvzfx	21	16	mutagens	mutagen	NNS
cord-021494-9glqvzfx	21	17	,	,	,
cord-021494-9glqvzfx	21	18	drugs	drug	NNS
cord-021494-9glqvzfx	21	19	,	,	,
cord-021494-9glqvzfx	21	20	allergens	allergen	NNS
cord-021494-9glqvzfx	21	21	,	,	,
cord-021494-9glqvzfx	21	22	trauma	trauma	NN
cord-021494-9glqvzfx	21	23	,	,	,
cord-021494-9glqvzfx	21	24	or	or	CC
cord-021494-9glqvzfx	21	25	genetic	genetic	JJ
cord-021494-9glqvzfx	21	26	mutations	mutation	NNS
cord-021494-9glqvzfx	21	27	)	)	-RRB-
cord-021494-9glqvzfx	21	28	.	.	.
cord-021494-9glqvzfx	22	1	A	a	DT
cord-021494-9glqvzfx	22	2	disease	disease	NN
cord-021494-9glqvzfx	22	3	is	be	VBZ
cord-021494-9glqvzfx	22	4	expected	expect	VBN
cord-021494-9glqvzfx	22	5	to	to	TO
cord-021494-9glqvzfx	22	6	follow	follow	VB
cord-021494-9glqvzfx	22	7	a	a	DT
cord-021494-9glqvzfx	22	8	particular	particular	JJ
cord-021494-9glqvzfx	22	9	series	series	NN
cord-021494-9glqvzfx	22	10	of	of	IN
cord-021494-9glqvzfx	22	11	events	event	NNS
cord-021494-9glqvzfx	22	12	in	in	IN
cord-021494-9glqvzfx	22	13	its	-PRON-	PRP$
cord-021494-9glqvzfx	22	14	development	development	NN
cord-021494-9glqvzfx	22	15	(	(	-LRB-
cord-021494-9glqvzfx	22	16	pathogenesis	pathogenesis	NN
cord-021494-9glqvzfx	22	17	)	)	-RRB-
cord-021494-9glqvzfx	22	18	,	,	,
cord-021494-9glqvzfx	22	19	and	and	CC
cord-021494-9glqvzfx	22	20	to	to	TO
cord-021494-9glqvzfx	22	21	follow	follow	VB
cord-021494-9glqvzfx	22	22	a	a	DT
cord-021494-9glqvzfx	22	23	particular	particular	JJ
cord-021494-9glqvzfx	22	24	clinical	clinical	JJ
cord-021494-9glqvzfx	22	25	course	course	NN
cord-021494-9glqvzfx	22	26	(	(	-LRB-
cord-021494-9glqvzfx	22	27	natural	natural	JJ
cord-021494-9glqvzfx	22	28	history	history	NN
cord-021494-9glqvzfx	22	29	)	)	-RRB-
cord-021494-9glqvzfx	22	30	.	.	.
cord-021494-9glqvzfx	23	1	Disease	Disease	NNP
cord-021494-9glqvzfx	23	2	can	can	MD
cord-021494-9glqvzfx	23	3	result	result	VB
cord-021494-9glqvzfx	23	4	in	in	IN
cord-021494-9glqvzfx	23	5	a	a	DT
cord-021494-9glqvzfx	23	6	temporary	temporary	JJ
cord-021494-9glqvzfx	23	7	or	or	CC
cord-021494-9glqvzfx	23	8	lasting	lasting	JJ
cord-021494-9glqvzfx	23	9	change	change	NN
cord-021494-9glqvzfx	23	10	in	in	IN
cord-021494-9glqvzfx	23	11	normal	normal	JJ
cord-021494-9glqvzfx	23	12	function	function	NN
cord-021494-9glqvzfx	23	13	,	,	,
cord-021494-9glqvzfx	23	14	including	include	VBG
cord-021494-9glqvzfx	23	15	patient	patient	JJ
cord-021494-9glqvzfx	23	16	death	death	NN
cord-021494-9glqvzfx	23	17	.	.	.
cord-021494-9glqvzfx	24	1	Multiple	multiple	JJ
cord-021494-9glqvzfx	24	2	diseases	disease	NNS
cord-021494-9glqvzfx	24	3	of	of	IN
cord-021494-9glqvzfx	24	4	different	different	JJ
cord-021494-9glqvzfx	24	5	etiologies	etiology	NNS
cord-021494-9glqvzfx	24	6	can	can	MD
cord-021494-9glqvzfx	24	7	affect	affect	VB
cord-021494-9glqvzfx	24	8	a	a	DT
cord-021494-9glqvzfx	24	9	single	single	JJ
cord-021494-9glqvzfx	24	10	organ	organ	NN
cord-021494-9glqvzfx	24	11	,	,	,
cord-021494-9glqvzfx	24	12	for	for	IN
cord-021494-9glqvzfx	24	13	example	example	NN
cord-021494-9glqvzfx	24	14	,	,	,
cord-021494-9glqvzfx	24	15	infectious	infectious	JJ
cord-021494-9glqvzfx	24	16	and	and	CC
cord-021494-9glqvzfx	24	17	neoplastic	neoplastic	JJ
cord-021494-9glqvzfx	24	18	diseases	disease	NNS
cord-021494-9glqvzfx	24	19	involving	involve	VBG
cord-021494-9glqvzfx	24	20	the	the	DT
cord-021494-9glqvzfx	24	21	lung	lung	NN
cord-021494-9glqvzfx	24	22	.	.	.
cord-021494-9glqvzfx	25	1	Different	different	JJ
cord-021494-9glqvzfx	25	2	diseases	disease	NNS
cord-021494-9glqvzfx	25	3	can	can	MD
cord-021494-9glqvzfx	25	4	derive	derive	VB
cord-021494-9glqvzfx	25	5	from	from	IN
cord-021494-9glqvzfx	25	6	a	a	DT
cord-021494-9glqvzfx	25	7	single	single	JJ
cord-021494-9glqvzfx	25	8	etiology	etiology	NN
cord-021494-9glqvzfx	25	9	,	,	,
cord-021494-9glqvzfx	25	10	for	for	IN
cord-021494-9glqvzfx	25	11	example	example	NN
cord-021494-9glqvzfx	25	12	,	,	,
cord-021494-9glqvzfx	25	13	emphysema	emphysema	NN
cord-021494-9glqvzfx	25	14	,	,	,
cord-021494-9glqvzfx	25	15	chronic	chronic	JJ
cord-021494-9glqvzfx	25	16	bronchitis	bronchitis	NN
cord-021494-9glqvzfx	25	17	,	,	,
cord-021494-9glqvzfx	25	18	and	and	CC
cord-021494-9glqvzfx	25	19	small	small	JJ
cord-021494-9glqvzfx	25	20	cell	cell	NN
cord-021494-9glqvzfx	25	21	lung	lung	NN
cord-021494-9glqvzfx	25	22	carcinoma	carcinoma	NN
cord-021494-9glqvzfx	25	23	in	in	IN
cord-021494-9glqvzfx	25	24	long	long	JJ
cord-021494-9glqvzfx	25	25	-	-	HYPH
cord-021494-9glqvzfx	25	26	term	term	NN
cord-021494-9glqvzfx	25	27	smokers	smoker	NNS
cord-021494-9glqvzfx	25	28	.	.	.
cord-021494-9glqvzfx	26	1	The	the	DT
cord-021494-9glqvzfx	26	2	same	same	JJ
cord-021494-9glqvzfx	26	3	disease	disease	NN
cord-021494-9glqvzfx	26	4	(	(	-LRB-
cord-021494-9glqvzfx	26	5	for	for	IN
cord-021494-9glqvzfx	26	6	instance	instance	NN
cord-021494-9glqvzfx	26	7	,	,	,
cord-021494-9glqvzfx	26	8	emphysema	emphysema	NN
cord-021494-9glqvzfx	26	9	of	of	IN
cord-021494-9glqvzfx	26	10	the	the	DT
cord-021494-9glqvzfx	26	11	lung	lung	NN
cord-021494-9glqvzfx	26	12	)	)	-RRB-
cord-021494-9glqvzfx	26	13	can	can	MD
cord-021494-9glqvzfx	26	14	derive	derive	VB
cord-021494-9glqvzfx	26	15	from	from	IN
cord-021494-9glqvzfx	26	16	different	different	JJ
cord-021494-9glqvzfx	26	17	etiologies	etiology	NNS
cord-021494-9glqvzfx	26	18	(	(	-LRB-
cord-021494-9glqvzfx	26	19	emphysema	emphysema	NN
cord-021494-9glqvzfx	26	20	from	from	IN
cord-021494-9glqvzfx	26	21	a-1-antitrypsin	a-1-antitrypsin	PRP$
cord-021494-9glqvzfx	26	22	deficiency	deficiency	NN
cord-021494-9glqvzfx	26	23	or	or	CC
cord-021494-9glqvzfx	26	24	cigarette	cigarette	NN
cord-021494-9glqvzfx	26	25	smoke	smoke	NN
cord-021494-9glqvzfx	26	26	)	)	-RRB-
cord-021494-9glqvzfx	26	27	.	.	.
cord-021494-9glqvzfx	27	1	Modern	modern	JJ
cord-021494-9glqvzfx	27	2	diagnostic	diagnostic	JJ
cord-021494-9glqvzfx	27	3	pathology	pathology	NN
cord-021494-9glqvzfx	27	4	practice	practice	NN
cord-021494-9glqvzfx	27	5	hinges	hinge	NNS
cord-021494-9glqvzfx	27	6	on	on	IN
cord-021494-9glqvzfx	27	7	morphologic	morphologic	JJ
cord-021494-9glqvzfx	27	8	diagnosis	diagnosis	NN
cord-021494-9glqvzfx	27	9	,	,	,
cord-021494-9glqvzfx	27	10	supplemented	supplement	VBN
cord-021494-9glqvzfx	27	11	by	by	IN
cord-021494-9glqvzfx	27	12	histochemical	histochemical	JJ
cord-021494-9glqvzfx	27	13	stains	stain	NNS
cord-021494-9glqvzfx	27	14	,	,	,
cord-021494-9glqvzfx	27	15	immunohistochemical	immunohistochemical	JJ
cord-021494-9glqvzfx	27	16	stains	stain	NNS
cord-021494-9glqvzfx	27	17	,	,	,
cord-021494-9glqvzfx	27	18	cytogenetics	cytogenetic	NNS
cord-021494-9glqvzfx	27	19	,	,	,
cord-021494-9glqvzfx	27	20	and	and	CC
cord-021494-9glqvzfx	27	21	clinical	clinical	JJ
cord-021494-9glqvzfx	27	22	laboratory	laboratory	NN
cord-021494-9glqvzfx	27	23	findings	finding	NNS
cord-021494-9glqvzfx	27	24	,	,	,
cord-021494-9glqvzfx	27	25	as	as	RB
cord-021494-9glqvzfx	27	26	well	well	RB
cord-021494-9glqvzfx	27	27	as	as	IN
cord-021494-9glqvzfx	27	28	the	the	DT
cord-021494-9glqvzfx	27	29	clinical	clinical	JJ
cord-021494-9glqvzfx	27	30	and	and	CC
cord-021494-9glqvzfx	27	31	radiographic	radiographic	JJ
cord-021494-9glqvzfx	27	32	findings	finding	NNS
cord-021494-9glqvzfx	27	33	.	.	.
cord-021494-9glqvzfx	28	1	Sections	section	NNS
cord-021494-9glqvzfx	28	2	that	that	WDT
cord-021494-9glqvzfx	28	3	meet	meet	VBP
cord-021494-9glqvzfx	28	4	all	all	DT
cord-021494-9glqvzfx	28	5	of	of	IN
cord-021494-9glqvzfx	28	6	these	these	DT
cord-021494-9glqvzfx	28	7	criteria	criterion	NNS
cord-021494-9glqvzfx	28	8	are	be	VBP
cord-021494-9glqvzfx	28	9	diagnostic	diagnostic	JJ
cord-021494-9glqvzfx	28	10	for	for	IN
cord-021494-9glqvzfx	28	11	the	the	DT
cord-021494-9glqvzfx	28	12	disease	disease	NN
cord-021494-9glqvzfx	28	13	.	.	.
cord-021494-9glqvzfx	29	1	If	if	IN
cord-021494-9glqvzfx	29	2	some	some	DT
cord-021494-9glqvzfx	29	3	,	,	,
cord-021494-9glqvzfx	29	4	but	but	CC
cord-021494-9glqvzfx	29	5	not	not	RB
cord-021494-9glqvzfx	29	6	all	all	DT
cord-021494-9glqvzfx	29	7	,	,	,
cord-021494-9glqvzfx	29	8	of	of	IN
cord-021494-9glqvzfx	29	9	the	the	DT
cord-021494-9glqvzfx	29	10	criteria	criterion	NNS
cord-021494-9glqvzfx	29	11	are	be	VBP
cord-021494-9glqvzfx	29	12	present	present	JJ
cord-021494-9glqvzfx	29	13	to	to	TO
cord-021494-9glqvzfx	29	14	make	make	VB
cord-021494-9glqvzfx	29	15	a	a	DT
cord-021494-9glqvzfx	29	16	definitive	definitive	JJ
cord-021494-9glqvzfx	29	17	diagnosis	diagnosis	NN
cord-021494-9glqvzfx	29	18	,	,	,
cord-021494-9glqvzfx	29	19	the	the	DT
cord-021494-9glqvzfx	29	20	pathologist	pathologist	NN
cord-021494-9glqvzfx	29	21	must	must	MD
cord-021494-9glqvzfx	29	22	either	either	CC
cord-021494-9glqvzfx	29	23	equivocate	equivocate	VB
cord-021494-9glqvzfx	29	24	or	or	CC
cord-021494-9glqvzfx	29	25	make	make	VB
cord-021494-9glqvzfx	29	26	an	an	DT
cord-021494-9glqvzfx	29	27	alternate	alternate	JJ
cord-021494-9glqvzfx	29	28	diagnosis	diagnosis	NN
cord-021494-9glqvzfx	29	29	.	.	.
cord-021494-9glqvzfx	30	1	Thus	thus	RB
cord-021494-9glqvzfx	30	2	,	,	,
cord-021494-9glqvzfx	30	3	a	a	DT
cord-021494-9glqvzfx	30	4	firm	firm	JJ
cord-021494-9glqvzfx	30	5	grasp	grasp	NN
cord-021494-9glqvzfx	30	6	of	of	IN
cord-021494-9glqvzfx	30	7	the	the	DT
cord-021494-9glqvzfx	30	8	diagnostic	diagnostic	JJ
cord-021494-9glqvzfx	30	9	criteria	criterion	NNS
cord-021494-9glqvzfx	30	10	and	and	CC
cord-021494-9glqvzfx	30	11	the	the	DT
cord-021494-9glqvzfx	30	12	instincts	instinct	NNS
cord-021494-9glqvzfx	30	13	to	to	TO
cord-021494-9glqvzfx	30	14	rapidly	rapidly	RB
cord-021494-9glqvzfx	30	15	create	create	VB
cord-021494-9glqvzfx	30	16	and	and	CC
cord-021494-9glqvzfx	30	17	sort	sort	VB
cord-021494-9glqvzfx	30	18	through	through	IN
cord-021494-9glqvzfx	30	19	the	the	DT
cord-021494-9glqvzfx	30	20	differential	differential	JJ
cord-021494-9glqvzfx	30	21	diagnosis	diagnosis	NN
cord-021494-9glqvzfx	30	22	must	must	MD
cord-021494-9glqvzfx	30	23	be	be	VB
cord-021494-9glqvzfx	30	24	possessed	possess	VBN
cord-021494-9glqvzfx	30	25	by	by	IN
cord-021494-9glqvzfx	30	26	the	the	DT
cord-021494-9glqvzfx	30	27	diagnostic	diagnostic	JJ
cord-021494-9glqvzfx	30	28	pathologist	pathologist	NN
cord-021494-9glqvzfx	30	29	.	.	.
cord-021494-9glqvzfx	31	1	The	the	DT
cord-021494-9glqvzfx	31	2	pathologic	pathologic	JJ
cord-021494-9glqvzfx	31	3	diagnosis	diagnosis	NN
cord-021494-9glqvzfx	31	4	has	have	VBZ
cord-021494-9glqvzfx	31	5	to	to	TO
cord-021494-9glqvzfx	31	6	make	make	VB
cord-021494-9glqvzfx	31	7	sense	sense	NN
cord-021494-9glqvzfx	31	8	,	,	,
cord-021494-9glqvzfx	31	9	not	not	RB
cord-021494-9glqvzfx	31	10	only	only	RB
cord-021494-9glqvzfx	31	11	from	from	IN
cord-021494-9glqvzfx	31	12	the	the	DT
cord-021494-9glqvzfx	31	13	morphologic	morphologic	JJ
cord-021494-9glqvzfx	31	14	perspective	perspective	NN
cord-021494-9glqvzfx	31	15	,	,	,
cord-021494-9glqvzfx	31	16	but	but	CC
cord-021494-9glqvzfx	31	17	from	from	IN
cord-021494-9glqvzfx	31	18	the	the	DT
cord-021494-9glqvzfx	31	19	clinical	clinical	JJ
cord-021494-9glqvzfx	31	20	and	and	CC
cord-021494-9glqvzfx	31	21	radiographic	radiographic	JJ
cord-021494-9glqvzfx	31	22	vantage	vantage	NN
cord-021494-9glqvzfx	31	23	points	point	NNS
cord-021494-9glqvzfx	31	24	as	as	RB
cord-021494-9glqvzfx	31	25	well	well	RB
cord-021494-9glqvzfx	31	26	.	.	.
cord-021494-9glqvzfx	32	1	It	-PRON-	PRP
cord-021494-9glqvzfx	32	2	is	be	VBZ
cord-021494-9glqvzfx	32	3	both	both	DT
cord-021494-9glqvzfx	32	4	legally	legally	RB
cord-021494-9glqvzfx	32	5	risky	risky	JJ
cord-021494-9glqvzfx	32	6	and	and	CC
cord-021494-9glqvzfx	32	7	professionally	professionally	RB
cord-021494-9glqvzfx	32	8	erosive	erosive	JJ
cord-021494-9glqvzfx	32	9	to	to	TO
cord-021494-9glqvzfx	32	10	make	make	VB
cord-021494-9glqvzfx	32	11	a	a	DT
cord-021494-9glqvzfx	32	12	clinically	clinically	RB
cord-021494-9glqvzfx	32	13	and	and	CC
cord-021494-9glqvzfx	32	14	pathologically	pathologically	RB
cord-021494-9glqvzfx	32	15	impossible	impossible	JJ
cord-021494-9glqvzfx	32	16	diagnosis	diagnosis	NN
cord-021494-9glqvzfx	32	17	.	.	.
cord-021494-9glqvzfx	33	1	In	in	IN
cord-021494-9glqvzfx	33	2	the	the	DT
cord-021494-9glqvzfx	33	3	recent	recent	JJ
cord-021494-9glqvzfx	33	4	past	past	NN
cord-021494-9glqvzfx	33	5	,	,	,
cord-021494-9glqvzfx	33	6	limited	limited	JJ
cord-021494-9glqvzfx	33	7	computer	computer	NN
cord-021494-9glqvzfx	33	8	networking	networking	NN
cord-021494-9glqvzfx	33	9	meant	mean	VBD
cord-021494-9glqvzfx	33	10	numerous	numerous	JJ
cord-021494-9glqvzfx	33	11	phone	phone	NN
cord-021494-9glqvzfx	33	12	calls	call	NNS
cord-021494-9glqvzfx	33	13	to	to	TO
cord-021494-9glqvzfx	33	14	gather	gather	VB
cord-021494-9glqvzfx	33	15	the	the	DT
cord-021494-9glqvzfx	33	16	relevant	relevant	JJ
cord-021494-9glqvzfx	33	17	clinical	clinical	JJ
cord-021494-9glqvzfx	33	18	and	and	CC
cord-021494-9glqvzfx	33	19	radiographic	radiographic	JJ
cord-021494-9glqvzfx	33	20	information	information	NN
cord-021494-9glqvzfx	33	21	to	to	TO
cord-021494-9glqvzfx	33	22	make	make	VB
cord-021494-9glqvzfx	33	23	an	an	DT
cord-021494-9glqvzfx	33	24	informed	informed	JJ
cord-021494-9glqvzfx	33	25	morphologic	morphologic	JJ
cord-021494-9glqvzfx	33	26	diagnosis	diagnosis	NN
cord-021494-9glqvzfx	33	27	.	.	.
cord-021494-9glqvzfx	34	1	For	for	IN
cord-021494-9glqvzfx	34	2	example	example	NN
cord-021494-9glqvzfx	34	3	,	,	,
cord-021494-9glqvzfx	34	4	certain	certain	JJ
cord-021494-9glqvzfx	34	5	diseases	disease	NNS
cord-021494-9glqvzfx	34	6	such	such	JJ
cord-021494-9glqvzfx	34	7	as	as	IN
cord-021494-9glqvzfx	34	8	squamous	squamous	JJ
cord-021494-9glqvzfx	34	9	and	and	CC
cord-021494-9glqvzfx	34	10	small	small	JJ
cord-021494-9glqvzfx	34	11	cell	cell	NN
cord-021494-9glqvzfx	34	12	carcinomas	carcinoma	NNS
cord-021494-9glqvzfx	34	13	of	of	IN
cord-021494-9glqvzfx	34	14	the	the	DT
cord-021494-9glqvzfx	34	15	lung	lung	NN
cord-021494-9glqvzfx	34	16	are	be	VBP
cord-021494-9glqvzfx	34	17	extremely	extremely	RB
cord-021494-9glqvzfx	34	18	rare	rare	JJ
cord-021494-9glqvzfx	34	19	in	in	IN
cord-021494-9glqvzfx	34	20	nonsmokers	nonsmoker	NNS
cord-021494-9glqvzfx	34	21	.	.	.
cord-021494-9glqvzfx	35	1	Thus	thus	RB
cord-021494-9glqvzfx	35	2	,	,	,
cord-021494-9glqvzfx	35	3	a	a	DT
cord-021494-9glqvzfx	35	4	small	small	JJ
cord-021494-9glqvzfx	35	5	cell	cell	NN
cord-021494-9glqvzfx	35	6	carcinoma	carcinoma	NN
cord-021494-9glqvzfx	35	7	in	in	IN
cord-021494-9glqvzfx	35	8	the	the	DT
cord-021494-9glqvzfx	35	9	lung	lung	NN
cord-021494-9glqvzfx	35	10	of	of	IN
cord-021494-9glqvzfx	35	11	a	a	DT
cord-021494-9glqvzfx	35	12	nonsmoker	nonsmoker	NN
cord-021494-9glqvzfx	35	13	merits	merit	NNS
cord-021494-9glqvzfx	35	14	screening	screen	VBG
cord-021494-9glqvzfx	35	15	for	for	IN
cord-021494-9glqvzfx	35	16	a	a	DT
cord-021494-9glqvzfx	35	17	nonpulmonary	nonpulmonary	JJ
cord-021494-9glqvzfx	35	18	primary	primary	JJ
cord-021494-9glqvzfx	35	19	site	site	NN
cord-021494-9glqvzfx	35	20	.	.	.
cord-021494-9glqvzfx	36	1	Fortunately	fortunately	RB
cord-021494-9glqvzfx	36	2	for	for	IN
cord-021494-9glqvzfx	36	3	pathologists	pathologist	NNS
cord-021494-9glqvzfx	36	4	,	,	,
cord-021494-9glqvzfx	36	5	computing	computing	NN
cord-021494-9glqvzfx	36	6	and	and	CC
cord-021494-9glqvzfx	36	7	networking	networking	NN
cord-021494-9glqvzfx	36	8	technologies	technology	NNS
cord-021494-9glqvzfx	36	9	now	now	RB
cord-021494-9glqvzfx	36	10	allow	allow	VBP
cord-021494-9glqvzfx	36	11	us	-PRON-	PRP
cord-021494-9glqvzfx	36	12	access	access	NN
cord-021494-9glqvzfx	36	13	to	to	IN
cord-021494-9glqvzfx	36	14	preoperative	preoperative	JJ
cord-021494-9glqvzfx	36	15	clinical	clinical	JJ
cord-021494-9glqvzfx	36	16	workups	workup	NNS
cord-021494-9glqvzfx	36	17	,	,	,
cord-021494-9glqvzfx	36	18	radiographs	radiograph	NNS
cord-021494-9glqvzfx	36	19	/	/	SYM
cord-021494-9glqvzfx	36	20	reports	report	NNS
cord-021494-9glqvzfx	36	21	,	,	,
cord-021494-9glqvzfx	36	22	clinical	clinical	JJ
cord-021494-9glqvzfx	36	23	laboratory	laboratory	NN
cord-021494-9glqvzfx	36	24	data	datum	NNS
cord-021494-9glqvzfx	36	25	,	,	,
cord-021494-9glqvzfx	36	26	and	and	CC
cord-021494-9glqvzfx	36	27	prior	prior	JJ
cord-021494-9glqvzfx	36	28	pathology	pathology	NN
cord-021494-9glqvzfx	36	29	reports	report	NNS
cord-021494-9glqvzfx	36	30	.	.	.
cord-021494-9glqvzfx	37	1	All	all	DT
cord-021494-9glqvzfx	37	2	of	of	IN
cord-021494-9glqvzfx	37	3	these	these	DT
cord-021494-9glqvzfx	37	4	data	datum	NNS
cord-021494-9glqvzfx	37	5	protect	protect	VBP
cord-021494-9glqvzfx	37	6	pathologists	pathologist	NNS
cord-021494-9glqvzfx	37	7	by	by	IN
cord-021494-9glqvzfx	37	8	providing	provide	VBG
cord-021494-9glqvzfx	37	9	them	-PRON-	PRP
cord-021494-9glqvzfx	37	10	with	with	IN
cord-021494-9glqvzfx	37	11	the	the	DT
cord-021494-9glqvzfx	37	12	relevant	relevant	JJ
cord-021494-9glqvzfx	37	13	clinical	clinical	JJ
cord-021494-9glqvzfx	37	14	and	and	CC
cord-021494-9glqvzfx	37	15	radiographic	radiographic	JJ
cord-021494-9glqvzfx	37	16	information	information	NN
cord-021494-9glqvzfx	37	17	,	,	,
cord-021494-9glqvzfx	37	18	and	and	CC
cord-021494-9glqvzfx	37	19	protect	protect	VB
cord-021494-9glqvzfx	37	20	patients	patient	NNS
cord-021494-9glqvzfx	37	21	by	by	IN
cord-021494-9glqvzfx	37	22	improving	improve	VBG
cord-021494-9glqvzfx	37	23	diagnostic	diagnostic	JJ
cord-021494-9glqvzfx	37	24	accuracy	accuracy	NN
cord-021494-9glqvzfx	37	25	.	.	.
cord-021494-9glqvzfx	38	1	Just	just	RB
cord-021494-9glqvzfx	38	2	as	as	IN
cord-021494-9glqvzfx	38	3	research	research	NN
cord-021494-9glqvzfx	38	4	scientists	scientist	NNS
cord-021494-9glqvzfx	38	5	"	"	''
cord-021494-9glqvzfx	38	6	.	.	.
cord-021494-9glqvzfx	38	7	.	.	.
cord-021494-9glqvzfx	38	8	.	.	.
cord-021494-9glqvzfx	39	1	ignore	ignore	VB
cord-021494-9glqvzfx	39	2	the	the	DT
cord-021494-9glqvzfx	39	3	literature	literature	NN
cord-021494-9glqvzfx	39	4	at	at	IN
cord-021494-9glqvzfx	39	5	their	-PRON-	PRP$
cord-021494-9glqvzfx	39	6	peril	peril	NN
cord-021494-9glqvzfx	39	7	.	.	.
cord-021494-9glqvzfx	39	8	.	.	.
cord-021494-9glqvzfx	39	9	.	.	.
cord-021494-9glqvzfx	40	1	"	"	``
cord-021494-9glqvzfx	40	2	,	,	,
cord-021494-9glqvzfx	40	3	diagnostic	diagnostic	JJ
cord-021494-9glqvzfx	40	4	pathologists	pathologist	NNS
cord-021494-9glqvzfx	40	5	"	"	''
cord-021494-9glqvzfx	40	6	.	.	.
cord-021494-9glqvzfx	40	7	.	.	.
cord-021494-9glqvzfx	40	8	.	.	.
cord-021494-9glqvzfx	41	1	ignore	ignore	VB
cord-021494-9glqvzfx	41	2	the	the	DT
cord-021494-9glqvzfx	41	3	presentation	presentation	NN
cord-021494-9glqvzfx	41	4	,	,	,
cord-021494-9glqvzfx	41	5	past	past	IN
cord-021494-9glqvzfx	41	6	history	history	NN
cord-021494-9glqvzfx	41	7	,	,	,
cord-021494-9glqvzfx	41	8	workup	workup	NN
cord-021494-9glqvzfx	41	9	,	,	,
cord-021494-9glqvzfx	41	10	prior	prior	JJ
cord-021494-9glqvzfx	41	11	biopsies	biopsy	NNS
cord-021494-9glqvzfx	41	12	,	,	,
cord-021494-9glqvzfx	41	13	and	and	CC
cord-021494-9glqvzfx	41	14	radiographs	radiograph	NNS
cord-021494-9glqvzfx	41	15	at	at	IN
cord-021494-9glqvzfx	41	16	their	-PRON-	PRP$
cord-021494-9glqvzfx	41	17	peril	peril	NN
cord-021494-9glqvzfx	41	18	.	.	.
cord-021494-9glqvzfx	41	19	.	.	.
cord-021494-9glqvzfx	41	20	.	.	.
cord-021494-9glqvzfx	41	21	.	.	.
cord-021494-9glqvzfx	42	1	"	"	``
cord-021494-9glqvzfx	42	2	There	there	EX
cord-021494-9glqvzfx	42	3	are	be	VBP
cord-021494-9glqvzfx	42	4	limitations	limitation	NNS
cord-021494-9glqvzfx	42	5	to	to	IN
cord-021494-9glqvzfx	42	6	morphologic	morphologic	JJ
cord-021494-9glqvzfx	42	7	diagnosis	diagnosis	NN
cord-021494-9glqvzfx	42	8	by	by	IN
cord-021494-9glqvzfx	42	9	H&E	H&E	NNP
cord-021494-9glqvzfx	42	10	stains	stain	NNS
cord-021494-9glqvzfx	42	11	.	.	.
cord-021494-9glqvzfx	43	1	First	first	RB
cord-021494-9glqvzfx	43	2	,	,	,
cord-021494-9glqvzfx	43	3	lineage	lineage	NN
cord-021494-9glqvzfx	43	4	of	of	IN
cord-021494-9glqvzfx	43	5	certain	certain	JJ
cord-021494-9glqvzfx	43	6	classes	class	NNS
cord-021494-9glqvzfx	43	7	of	of	IN
cord-021494-9glqvzfx	43	8	neoplasms	neoplasm	NNS
cord-021494-9glqvzfx	43	9	(	(	-LRB-
cord-021494-9glqvzfx	43	10	including	include	VBG
cord-021494-9glqvzfx	43	11	small	small	JJ
cord-021494-9glqvzfx	43	12	round	round	JJ
cord-021494-9glqvzfx	43	13	blue	blue	JJ
cord-021494-9glqvzfx	43	14	cell	cell	NN
cord-021494-9glqvzfx	43	15	tumors	tumor	NNS
cord-021494-9glqvzfx	43	16	,	,	,
cord-021494-9glqvzfx	43	17	clear	clear	JJ
cord-021494-9glqvzfx	43	18	cell	cell	NN
cord-021494-9glqvzfx	43	19	neoplasms	neoplasm	NNS
cord-021494-9glqvzfx	43	20	,	,	,
cord-021494-9glqvzfx	43	21	spindle	spindle	NN
cord-021494-9glqvzfx	43	22	cell	cell	NN
cord-021494-9glqvzfx	43	23	neoplasms	neoplasm	NNS
cord-021494-9glqvzfx	43	24	,	,	,
cord-021494-9glqvzfx	43	25	and	and	CC
cord-021494-9glqvzfx	43	26	undifferentiated	undifferentiated	JJ
cord-021494-9glqvzfx	43	27	malignant	malignant	JJ
cord-021494-9glqvzfx	43	28	neoplasms	neoplasm	NNS
cord-021494-9glqvzfx	43	29	)	)	-RRB-
cord-021494-9glqvzfx	43	30	is	be	VBZ
cord-021494-9glqvzfx	43	31	usually	usually	RB
cord-021494-9glqvzfx	43	32	clarified	clarify	VBN
cord-021494-9glqvzfx	43	33	by	by	IN
cord-021494-9glqvzfx	43	34	immunohistochemistry	immunohistochemistry	NN
cord-021494-9glqvzfx	43	35	,	,	,
cord-021494-9glqvzfx	43	36	frequently	frequently	RB
cord-021494-9glqvzfx	43	37	by	by	IN
cord-021494-9glqvzfx	43	38	cytogenetics	cytogenetic	NNS
cord-021494-9glqvzfx	43	39	(	(	-LRB-
cord-021494-9glqvzfx	43	40	when	when	WRB
cord-021494-9glqvzfx	43	41	performed	perform	VBN
cord-021494-9glqvzfx	43	42	)	)	-RRB-
cord-021494-9glqvzfx	43	43	,	,	,
cord-021494-9glqvzfx	43	44	and	and	CC
cord-021494-9glqvzfx	43	45	sometimes	sometimes	RB
cord-021494-9glqvzfx	43	46	by	by	IN
cord-021494-9glqvzfx	43	47	electron	electron	NN
cord-021494-9glqvzfx	43	48	microscopy	microscopy	NN
cord-021494-9glqvzfx	43	49	.	.	.
cord-021494-9glqvzfx	44	1	Second	second	RB
cord-021494-9glqvzfx	44	2	,	,	,
cord-021494-9glqvzfx	44	3	there	there	EX
cord-021494-9glqvzfx	44	4	are	be	VBP
cord-021494-9glqvzfx	44	5	limitations	limitation	NNS
cord-021494-9glqvzfx	44	6	inherent	inherent	JJ
cord-021494-9glqvzfx	44	7	in	in	IN
cord-021494-9glqvzfx	44	8	a	a	DT
cord-021494-9glqvzfx	44	9	snapshot	snapshot	JJ
cord-021494-9glqvzfx	44	10	biopsy	biopsy	NN
cord-021494-9glqvzfx	44	11	or	or	CC
cord-021494-9glqvzfx	44	12	resection	resection	NN
cord-021494-9glqvzfx	44	13	.	.	.
cord-021494-9glqvzfx	45	1	Thus	thus	RB
cord-021494-9glqvzfx	45	2	,	,	,
cord-021494-9glqvzfx	45	3	the	the	DT
cord-021494-9glqvzfx	45	4	etiology	etiology	NN
cord-021494-9glqvzfx	45	5	and	and	CC
cord-021494-9glqvzfx	45	6	pathogenesis	pathogenesis	NN
cord-021494-9glqvzfx	45	7	can	can	MD
cord-021494-9glqvzfx	45	8	be	be	VB
cord-021494-9glqvzfx	45	9	obscure	obscure	JJ
cord-021494-9glqvzfx	45	10	or	or	CC
cord-021494-9glqvzfx	45	11	indeterminate	indeterminate	JJ
cord-021494-9glqvzfx	45	12	,	,	,
cord-021494-9glqvzfx	45	13	and	and	CC
cord-021494-9glqvzfx	45	14	rates	rate	NNS
cord-021494-9glqvzfx	45	15	of	of	IN
cord-021494-9glqvzfx	45	16	growth	growth	NN
cord-021494-9glqvzfx	45	17	,	,	,
cord-021494-9glqvzfx	45	18	invasion	invasion	NN
cord-021494-9glqvzfx	45	19	,	,	,
cord-021494-9glqvzfx	45	20	or	or	CC
cord-021494-9glqvzfx	45	21	timing	timing	NN
cord-021494-9glqvzfx	45	22	of	of	IN
cord-021494-9glqvzfx	45	23	metastasis	metastasis	NN
cord-021494-9glqvzfx	45	24	can	can	MD
cord-021494-9glqvzfx	45	25	not	not	RB
cord-021494-9glqvzfx	45	26	be	be	VB
cord-021494-9glqvzfx	45	27	inferred	infer	VBN
cord-021494-9glqvzfx	45	28	.	.	.
cord-021494-9glqvzfx	46	1	Third	third	RB
cord-021494-9glqvzfx	46	2	,	,	,
cord-021494-9glqvzfx	46	3	the	the	DT
cord-021494-9glqvzfx	46	4	morphologic	morphologic	JJ
cord-021494-9glqvzfx	46	5	changes	change	NNS
cord-021494-9glqvzfx	46	6	may	may	MD
cord-021494-9glqvzfx	46	7	not	not	RB
cord-021494-9glqvzfx	46	8	be	be	VB
cord-021494-9glqvzfx	46	9	specific	specific	JJ
cord-021494-9glqvzfx	46	10	for	for	IN
cord-021494-9glqvzfx	46	11	the	the	DT
cord-021494-9glqvzfx	46	12	underlying	underlying	JJ
cord-021494-9glqvzfx	46	13	molecular	molecular	JJ
cord-021494-9glqvzfx	46	14	abnormalities	abnormality	NNS
cord-021494-9glqvzfx	46	15	,	,	,
cord-021494-9glqvzfx	46	16	particularly	particularly	RB
cord-021494-9glqvzfx	46	17	the	the	DT
cord-021494-9glqvzfx	46	18	rate	rate	NN
cord-021494-9glqvzfx	46	19	-	-	HYPH
cord-021494-9glqvzfx	46	20	limiting	limit	VBG
cord-021494-9glqvzfx	46	21	(	(	-LRB-
cord-021494-9glqvzfx	46	22	therapeutic	therapeutic	JJ
cord-021494-9glqvzfx	46	23	target	target	NN
cord-021494-9glqvzfx	46	24	)	)	-RRB-
cord-021494-9glqvzfx	46	25	step	step	NN
cord-021494-9glqvzfx	46	26	in	in	IN
cord-021494-9glqvzfx	46	27	the	the	DT
cord-021494-9glqvzfx	46	28	pathogenesis	pathogenesis	NN
cord-021494-9glqvzfx	46	29	of	of	IN
cord-021494-9glqvzfx	46	30	a	a	DT
cord-021494-9glqvzfx	46	31	neoplasm	neoplasm	NN
cord-021494-9glqvzfx	46	32	.	.	.
cord-021494-9glqvzfx	47	1	For	for	IN
cord-021494-9glqvzfx	47	2	example	example	NN
cord-021494-9glqvzfx	47	3	,	,	,
cord-021494-9glqvzfx	47	4	Ret	Ret	NNP
cord-021494-9glqvzfx	47	5	gain	gain	NN
cord-021494-9glqvzfx	47	6	of	of	IN
cord-021494-9glqvzfx	47	7	function	function	NN
cord-021494-9glqvzfx	47	8	mutations	mutation	NNS
cord-021494-9glqvzfx	47	9	in	in	IN
cord-021494-9glqvzfx	47	10	a	a	DT
cord-021494-9glqvzfx	47	11	medullary	medullary	JJ
cord-021494-9glqvzfx	47	12	thyroid	thyroid	NN
cord-021494-9glqvzfx	47	13	carcinoma	carcinoma	NN
cord-021494-9glqvzfx	47	14	will	will	MD
cord-021494-9glqvzfx	47	15	require	require	VB
cord-021494-9glqvzfx	47	16	DNA	dna	NN
cord-021494-9glqvzfx	47	17	level	level	NN
cord-021494-9glqvzfx	47	18	screening	screening	NN
cord-021494-9glqvzfx	47	19	to	to	TO
cord-021494-9glqvzfx	47	20	determine	determine	VB
cord-021494-9glqvzfx	47	21	germline	germline	JJ
cord-021494-9glqvzfx	47	22	involvement	involvement	NN
cord-021494-9glqvzfx	47	23	,	,	,
cord-021494-9glqvzfx	47	24	familial	familial	JJ
cord-021494-9glqvzfx	47	25	risk	risk	NN
cord-021494-9glqvzfx	47	26	,	,	,
cord-021494-9glqvzfx	47	27	and	and	CC
cord-021494-9glqvzfx	47	28	presence	presence	NN
cord-021494-9glqvzfx	47	29	or	or	CC
cord-021494-9glqvzfx	47	30	absence	absence	NN
cord-021494-9glqvzfx	47	31	of	of	IN
cord-021494-9glqvzfx	47	32	a	a	DT
cord-021494-9glqvzfx	47	33	therapeutic	therapeutic	JJ
cord-021494-9glqvzfx	47	34	target	target	NN
cord-021494-9glqvzfx	47	35	.	.	.
cord-021494-9glqvzfx	48	1	Fourth	fourth	RB
cord-021494-9glqvzfx	48	2	,	,	,
cord-021494-9glqvzfx	48	3	the	the	DT
cord-021494-9glqvzfx	48	4	same	same	JJ
cord-021494-9glqvzfx	48	5	morphologic	morphologic	JJ
cord-021494-9glqvzfx	48	6	appearance	appearance	NN
cord-021494-9glqvzfx	48	7	may	may	MD
cord-021494-9glqvzfx	48	8	be	be	VB
cord-021494-9glqvzfx	48	9	identical	identical	JJ
cord-021494-9glqvzfx	48	10	for	for	IN
cord-021494-9glqvzfx	48	11	two	two	CD
cord-021494-9glqvzfx	48	12	different	different	JJ
cord-021494-9glqvzfx	48	13	diseases	disease	NNS
cord-021494-9glqvzfx	48	14	,	,	,
cord-021494-9glqvzfx	48	15	each	each	DT
cord-021494-9glqvzfx	48	16	of	of	IN
cord-021494-9glqvzfx	48	17	which	which	WDT
cord-021494-9glqvzfx	48	18	would	would	MD
cord-021494-9glqvzfx	48	19	be	be	VB
cord-021494-9glqvzfx	48	20	treated	treat	VBN
cord-021494-9glqvzfx	48	21	differently	differently	RB
cord-021494-9glqvzfx	48	22	.	.	.
cord-021494-9glqvzfx	49	1	For	for	IN
cord-021494-9glqvzfx	49	2	example	example	NN
cord-021494-9glqvzfx	49	3	,	,	,
cord-021494-9glqvzfx	49	4	there	there	EX
cord-021494-9glqvzfx	49	5	is	be	VBZ
cord-021494-9glqvzfx	49	6	no	no	DT
cord-021494-9glqvzfx	49	7	morphologic	morphologic	JJ
cord-021494-9glqvzfx	49	8	evidence	evidence	NN
cord-021494-9glqvzfx	49	9	by	by	IN
cord-021494-9glqvzfx	49	10	H&E	H&E	NNP
cord-021494-9glqvzfx	49	11	stain	stain	VB
cord-021494-9glqvzfx	49	12	alone	alone	RB
cord-021494-9glqvzfx	49	13	to	to	TO
cord-021494-9glqvzfx	49	14	distinguish	distinguish	VB
cord-021494-9glqvzfx	49	15	host	host	NN
cord-021494-9glqvzfx	49	16	lymphoid	lymphoid	JJ
cord-021494-9glqvzfx	49	17	response	response	NN
cord-021494-9glqvzfx	49	18	to	to	IN
cord-021494-9glqvzfx	49	19	hepatitis	hepatitis	NN
cord-021494-9glqvzfx	49	20	C	C	NNP
cord-021494-9glqvzfx	49	21	viral	viral	JJ
cord-021494-9glqvzfx	49	22	(	(	-LRB-
cord-021494-9glqvzfx	49	23	HCV	HCV	NNP
cord-021494-9glqvzfx	49	24	)	)	-RRB-
cord-021494-9glqvzfx	49	25	antigens	antigen	NNS
cord-021494-9glqvzfx	49	26	from	from	IN
cord-021494-9glqvzfx	49	27	host	host	NN
cord-021494-9glqvzfx	49	28	lymphoid	lymphoid	JJ
cord-021494-9glqvzfx	49	29	response	response	NN
cord-021494-9glqvzfx	49	30	to	to	IN
cord-021494-9glqvzfx	49	31	allo	allo	NNP
cord-021494-9glqvzfx	49	32	-	-	HYPH
cord-021494-9glqvzfx	49	33	HLA	HLA	NNP
cord-021494-9glqvzfx	49	34	antigens	antigen	NNS
cord-021494-9glqvzfx	49	35	in	in	IN
cord-021494-9glqvzfx	49	36	a	a	DT
cord-021494-9glqvzfx	49	37	liver	liver	NN
cord-021494-9glqvzfx	49	38	allograft	allograft	NN
cord-021494-9glqvzfx	49	39	.	.	.
cord-021494-9glqvzfx	50	1	This	this	DT
cord-021494-9glqvzfx	50	2	is	be	VBZ
cord-021494-9glqvzfx	50	3	obviously	obviously	RB
cord-021494-9glqvzfx	50	4	a	a	DT
cord-021494-9glqvzfx	50	5	major	major	JJ
cord-021494-9glqvzfx	50	6	diagnostic	diagnostic	JJ
cord-021494-9glqvzfx	50	7	challenge	challenge	NN
cord-021494-9glqvzfx	50	8	when	when	WRB
cord-021494-9glqvzfx	50	9	the	the	DT
cord-021494-9glqvzfx	50	10	transplant	transplant	NN
cord-021494-9glqvzfx	50	11	was	be	VBD
cord-021494-9glqvzfx	50	12	done	do	VBN
cord-021494-9glqvzfx	50	13	for	for	IN
cord-021494-9glqvzfx	50	14	HCV	HCV	NNP
cord-021494-9glqvzfx	50	15	-	-	HYPH
cord-021494-9glqvzfx	50	16	related	relate	VBN
cord-021494-9glqvzfx	50	17	cirrhosis	cirrhosis	NN
cord-021494-9glqvzfx	50	18	,	,	,
cord-021494-9glqvzfx	50	19	and	and	CC
cord-021494-9glqvzfx	50	20	the	the	DT
cord-021494-9glqvzfx	50	21	probability	probability	NN
cord-021494-9glqvzfx	50	22	of	of	IN
cord-021494-9glqvzfx	50	23	recurrent	recurrent	JJ
cord-021494-9glqvzfx	50	24	HCV	HCV	NNP
cord-021494-9glqvzfx	50	25	infection	infection	NN
cord-021494-9glqvzfx	50	26	in	in	IN
cord-021494-9glqvzfx	50	27	the	the	DT
cord-021494-9glqvzfx	50	28	liver	liver	NN
cord-021494-9glqvzfx	50	29	allograft	allograft	NN
cord-021494-9glqvzfx	50	30	is	be	VBZ
cord-021494-9glqvzfx	50	31	high	high	JJ
cord-021494-9glqvzfx	50	32	.	.	.
cord-021494-9glqvzfx	51	1	Paraffin	paraffin	NN
cord-021494-9glqvzfx	51	2	section	section	NN
cord-021494-9glqvzfx	51	3	immunohistochemistry	immunohistochemistry	NN
cord-021494-9glqvzfx	51	4	has	have	VBZ
cord-021494-9glqvzfx	51	5	proven	prove	VBN
cord-021494-9glqvzfx	51	6	invaluable	invaluable	JJ
cord-021494-9glqvzfx	51	7	in	in	IN
cord-021494-9glqvzfx	51	8	neoplasm	neoplasm	JJ
cord-021494-9glqvzfx	51	9	diagnosis	diagnosis	NN
cord-021494-9glqvzfx	51	10	for	for	IN
cord-021494-9glqvzfx	51	11	clarifying	clarify	VBG
cord-021494-9glqvzfx	51	12	lineage	lineage	NN
cord-021494-9glqvzfx	51	13	,	,	,
cord-021494-9glqvzfx	51	14	improving	improve	VBG
cord-021494-9glqvzfx	51	15	diagnostic	diagnostic	JJ
cord-021494-9glqvzfx	51	16	accuracy	accuracy	NN
cord-021494-9glqvzfx	51	17	,	,	,
cord-021494-9glqvzfx	51	18	and	and	CC
cord-021494-9glqvzfx	51	19	guiding	guide	VBG
cord-021494-9glqvzfx	51	20	customized	customize	VBN
cord-021494-9glqvzfx	51	21	therapy	therapy	NN
cord-021494-9glqvzfx	51	22	.	.	.
cord-021494-9glqvzfx	52	1	If	if	IN
cord-021494-9glqvzfx	52	2	neoplasms	neoplasm	NNS
cord-021494-9glqvzfx	52	3	are	be	VBP
cord-021494-9glqvzfx	52	4	poorly	poorly	RB
cord-021494-9glqvzfx	52	5	differentiated	differentiate	VBN
cord-021494-9glqvzfx	52	6	or	or	CC
cord-021494-9glqvzfx	52	7	undifferentiated	undifferentiated	JJ
cord-021494-9glqvzfx	52	8	,	,	,
cord-021494-9glqvzfx	52	9	the	the	DT
cord-021494-9glqvzfx	52	10	lineage	lineage	NN
cord-021494-9glqvzfx	52	11	of	of	IN
cord-021494-9glqvzfx	52	12	the	the	DT
cord-021494-9glqvzfx	52	13	neoplasm	neoplasm	NN
cord-021494-9glqvzfx	52	14	may	may	MD
cord-021494-9glqvzfx	52	15	not	not	RB
cord-021494-9glqvzfx	52	16	be	be	VB
cord-021494-9glqvzfx	52	17	clear	clear	JJ
cord-021494-9glqvzfx	52	18	.	.	.
cord-021494-9glqvzfx	53	1	For	for	IN
cord-021494-9glqvzfx	53	2	example	example	NN
cord-021494-9glqvzfx	53	3	,	,	,
cord-021494-9glqvzfx	53	4	sheets	sheet	NNS
cord-021494-9glqvzfx	53	5	of	of	IN
cord-021494-9glqvzfx	53	6	undifferentiated	undifferentiated	JJ
cord-021494-9glqvzfx	53	7	malignant	malignant	JJ
cord-021494-9glqvzfx	53	8	neoplasm	neoplasm	NN
cord-021494-9glqvzfx	53	9	with	with	IN
cord-021494-9glqvzfx	53	10	prominent	prominent	JJ
cord-021494-9glqvzfx	53	11	nucleoli	nucleolus	NNS
cord-021494-9glqvzfx	53	12	could	could	MD
cord-021494-9glqvzfx	53	13	represent	represent	VB
cord-021494-9glqvzfx	53	14	carcinoma	carcinoma	NN
cord-021494-9glqvzfx	53	15	,	,	,
cord-021494-9glqvzfx	53	16	lymphoma	lymphoma	NN
cord-021494-9glqvzfx	53	17	,	,	,
cord-021494-9glqvzfx	53	18	or	or	CC
cord-021494-9glqvzfx	53	19	melanoma	melanoma	NN
cord-021494-9glqvzfx	53	20	.	.	.
cord-021494-9glqvzfx	54	1	To	to	TO
cord-021494-9glqvzfx	54	2	clarify	clarify	VB
cord-021494-9glqvzfx	54	3	lineage	lineage	NN
cord-021494-9glqvzfx	54	4	,	,	,
cord-021494-9glqvzfx	54	5	a	a	DT
cord-021494-9glqvzfx	54	6	panel	panel	NN
cord-021494-9glqvzfx	54	7	of	of	IN
cord-021494-9glqvzfx	54	8	immunostains	immunostains	NNP
cord-021494-9glqvzfx	54	9	is	be	VBZ
cord-021494-9glqvzfx	54	10	performed	perform	VBN
cord-021494-9glqvzfx	54	11	for	for	IN
cord-021494-9glqvzfx	54	12	proteins	protein	NNS
cord-021494-9glqvzfx	54	13	that	that	WDT
cord-021494-9glqvzfx	54	14	are	be	VBP
cord-021494-9glqvzfx	54	15	expressed	express	VBN
cord-021494-9glqvzfx	54	16	in	in	IN
cord-021494-9glqvzfx	54	17	some	some	DT
cord-021494-9glqvzfx	54	18	of	of	IN
cord-021494-9glqvzfx	54	19	the	the	DT
cord-021494-9glqvzfx	54	20	neoplasms	neoplasm	NNS
cord-021494-9glqvzfx	54	21	,	,	,
cord-021494-9glqvzfx	54	22	but	but	CC
cord-021494-9glqvzfx	54	23	not	not	RB
cord-021494-9glqvzfx	54	24	in	in	IN
cord-021494-9glqvzfx	54	25	others	other	NNS
cord-021494-9glqvzfx	54	26	.	.	.
cord-021494-9glqvzfx	55	1	Relative	relative	JJ
cord-021494-9glqvzfx	55	2	probabilities	probability	NNS
cord-021494-9glqvzfx	55	3	are	be	VBP
cord-021494-9glqvzfx	55	4	then	then	RB
cord-021494-9glqvzfx	55	5	used	use	VBN
cord-021494-9glqvzfx	55	6	to	to	TO
cord-021494-9glqvzfx	55	7	lend	lend	VB
cord-021494-9glqvzfx	55	8	support	support	NN
cord-021494-9glqvzfx	55	9	(	(	-LRB-
cord-021494-9glqvzfx	55	10	rule	rule	NN
cord-021494-9glqvzfx	55	11	in	in	IN
cord-021494-9glqvzfx	55	12	)	)	-RRB-
cord-021494-9glqvzfx	55	13	or	or	CC
cord-021494-9glqvzfx	55	14	exclude	exclude	VB
cord-021494-9glqvzfx	55	15	(	(	-LRB-
cord-021494-9glqvzfx	55	16	rule	rule	VB
cord-021494-9glqvzfx	55	17	out	out	RP
cord-021494-9glqvzfx	55	18	)	)	-RRB-
cord-021494-9glqvzfx	55	19	particular	particular	JJ
cord-021494-9glqvzfx	55	20	diagnoses	diagnosis	NNS
cord-021494-9glqvzfx	55	21	in	in	IN
cord-021494-9glqvzfx	55	22	the	the	DT
cord-021494-9glqvzfx	55	23	differential	differential	JJ
cord-021494-9glqvzfx	55	24	diagnosis	diagnosis	NN
cord-021494-9glqvzfx	55	25	of	of	IN
cord-021494-9glqvzfx	55	26	these	these	DT
cord-021494-9glqvzfx	55	27	several	several	JJ
cord-021494-9glqvzfx	55	28	morphologically	morphologically	RB
cord-021494-9glqvzfx	55	29	similar	similar	JJ
cord-021494-9glqvzfx	55	30	undifferentiated	undifferentiated	JJ
cord-021494-9glqvzfx	55	31	neoplasms	neoplasm	NNS
cord-021494-9glqvzfx	55	32	.	.	.
cord-021494-9glqvzfx	56	1	The	the	DT
cord-021494-9glqvzfx	56	2	second	second	JJ
cord-021494-9glqvzfx	56	3	role	role	NN
cord-021494-9glqvzfx	56	4	is	be	VBZ
cord-021494-9glqvzfx	56	5	to	to	TO
cord-021494-9glqvzfx	56	6	make	make	VB
cord-021494-9glqvzfx	56	7	critical	critical	JJ
cord-021494-9glqvzfx	56	8	distinctions	distinction	NNS
cord-021494-9glqvzfx	56	9	in	in	IN
cord-021494-9glqvzfx	56	10	diagnosis	diagnosis	NN
cord-021494-9glqvzfx	56	11	that	that	WDT
cord-021494-9glqvzfx	56	12	can	can	MD
cord-021494-9glqvzfx	56	13	not	not	RB
cord-021494-9glqvzfx	56	14	be	be	VB
cord-021494-9glqvzfx	56	15	accurately	accurately	RB
cord-021494-9glqvzfx	56	16	made	make	VBN
cord-021494-9glqvzfx	56	17	by	by	IN
cord-021494-9glqvzfx	56	18	H&E	H&E	NNP
cord-021494-9glqvzfx	56	19	alone	alone	JJ
cord-021494-9glqvzfx	56	20	.	.	.
cord-021494-9glqvzfx	57	1	Examples	example	NNS
cord-021494-9glqvzfx	57	2	of	of	IN
cord-021494-9glqvzfx	57	3	this	this	DT
cord-021494-9glqvzfx	57	4	would	would	MD
cord-021494-9glqvzfx	57	5	include	include	VB
cord-021494-9glqvzfx	57	6	demonstration	demonstration	NN
cord-021494-9glqvzfx	57	7	of	of	IN
cord-021494-9glqvzfx	57	8	myoepithelial	myoepithelial	JJ
cord-021494-9glqvzfx	57	9	cell	cell	NN
cord-021494-9glqvzfx	57	10	loss	loss	NN
cord-021494-9glqvzfx	57	11	in	in	IN
cord-021494-9glqvzfx	57	12	invasive	invasive	JJ
cord-021494-9glqvzfx	57	13	breast	breast	NN
cord-021494-9glqvzfx	57	14	carcinoma	carcinoma	NN
cord-021494-9glqvzfx	57	15	but	but	CC
cord-021494-9glqvzfx	57	16	not	not	RB
cord-021494-9glqvzfx	57	17	in	in	IN
cord-021494-9glqvzfx	57	18	its	-PRON-	PRP$
cord-021494-9glqvzfx	57	19	mimic	mimic	JJ
cord-021494-9glqvzfx	57	20	,	,	,
cord-021494-9glqvzfx	57	21	sclerosing	sclerose	VBG
cord-021494-9glqvzfx	57	22	adenosis	adenosis	NN
cord-021494-9glqvzfx	57	23	(	(	-LRB-
cord-021494-9glqvzfx	57	24	Figure	figure	NN
cord-021494-9glqvzfx	57	25	11	11	CD
cord-021494-9glqvzfx	57	26	.1	.1	CD
cord-021494-9glqvzfx	57	27	)	)	-RRB-
cord-021494-9glqvzfx	57	28	,	,	,
cord-021494-9glqvzfx	57	29	or	or	CC
cord-021494-9glqvzfx	57	30	loss	loss	NN
cord-021494-9glqvzfx	57	31	of	of	IN
cord-021494-9glqvzfx	57	32	basal	basal	NN
cord-021494-9glqvzfx	57	33	cells	cell	NNS
cord-021494-9glqvzfx	57	34	in	in	IN
cord-021494-9glqvzfx	57	35	invasive	invasive	JJ
cord-021494-9glqvzfx	57	36	prostate	prostate	NN
cord-021494-9glqvzfx	57	37	carcinoma	carcinoma	NN
cord-021494-9glqvzfx	57	38	(	(	-LRB-
cord-021494-9glqvzfx	57	39	Figure	figure	NN
cord-021494-9glqvzfx	57	40	11	11	CD
cord-021494-9glqvzfx	57	41	.2	.2	CD
cord-021494-9glqvzfx	57	42	)	)	-RRB-
cord-021494-9glqvzfx	57	43	.	.	.
cord-021494-9glqvzfx	58	1	The	the	DT
cord-021494-9glqvzfx	58	2	third	third	JJ
cord-021494-9glqvzfx	58	3	role	role	NN
cord-021494-9glqvzfx	58	4	of	of	IN
cord-021494-9glqvzfx	58	5	immunohistochemistry	immunohistochemistry	NN
cord-021494-9glqvzfx	58	6	is	be	VBZ
cord-021494-9glqvzfx	58	7	to	to	TO
cord-021494-9glqvzfx	58	8	identify	identify	VB
cord-021494-9glqvzfx	58	9	particular	particular	JJ
cord-021494-9glqvzfx	58	10	proteins	protein	NNS
cord-021494-9glqvzfx	58	11	,	,	,
cord-021494-9glqvzfx	58	12	such	such	JJ
cord-021494-9glqvzfx	58	13	as	as	IN
cord-021494-9glqvzfx	58	14	nuclear	nuclear	JJ
cord-021494-9glqvzfx	58	15	estrogen	estrogen	NN
cord-021494-9glqvzfx	58	16	receptor	receptor	NN
cord-021494-9glqvzfx	58	17	(	(	-LRB-
cord-021494-9glqvzfx	58	18	ER	ER	NNP
cord-021494-9glqvzfx	58	19	)	)	-RRB-
cord-021494-9glqvzfx	58	20	(	(	-LRB-
cord-021494-9glqvzfx	58	21	Figure	figure	NN
cord-021494-9glqvzfx	58	22	11	11	CD
cord-021494-9glqvzfx	58	23	.3	.3	NFP
cord-021494-9glqvzfx	58	24	)	)	-RRB-
cord-021494-9glqvzfx	58	25	or	or	CC
cord-021494-9glqvzfx	58	26	the	the	DT
cord-021494-9glqvzfx	58	27	plasma	plasma	NN
cord-021494-9glqvzfx	58	28	membrane	membrane	NN
cord-021494-9glqvzfx	58	29	HER2	HER2	NNP
cord-021494-9glqvzfx	58	30	proteins	protein	NNS
cord-021494-9glqvzfx	58	31	(	(	-LRB-
cord-021494-9glqvzfx	58	32	Figure	figure	NN
cord-021494-9glqvzfx	58	33	11.4	11.4	CD
cord-021494-9glqvzfx	58	34	)	)	-RRB-
cord-021494-9glqvzfx	58	35	,	,	,
cord-021494-9glqvzfx	58	36	both	both	DT
cord-021494-9glqvzfx	58	37	of	of	IN
cord-021494-9glqvzfx	58	38	which	which	WDT
cord-021494-9glqvzfx	58	39	can	can	MD
cord-021494-9glqvzfx	58	40	be	be	VB
cord-021494-9glqvzfx	58	41	targeted	target	VBN
cord-021494-9glqvzfx	58	42	with	with	IN
cord-021494-9glqvzfx	58	43	inhibitors	inhibitor	NNS
cord-021494-9glqvzfx	58	44	rather	rather	RB
cord-021494-9glqvzfx	58	45	than	than	IN
cord-021494-9glqvzfx	58	46	generalized	generalize	VBN
cord-021494-9glqvzfx	58	47	systemic	systemic	JJ
cord-021494-9glqvzfx	58	48	chemotherapy	chemotherapy	NN
cord-021494-9glqvzfx	58	49	.	.	.
cord-021494-9glqvzfx	59	1	Morphology	morphology	NN
cord-021494-9glqvzfx	59	2	remains	remain	VBZ
cord-021494-9glqvzfx	59	3	the	the	DT
cord-021494-9glqvzfx	59	4	gold	gold	NN
cord-021494-9glqvzfx	59	5	standard	standard	NN
cord-021494-9glqvzfx	59	6	in	in	IN
cord-021494-9glqvzfx	59	7	this	this	DT
cord-021494-9glqvzfx	59	8	diagnostic	diagnostic	JJ
cord-021494-9glqvzfx	59	9	process	process	NN
cord-021494-9glqvzfx	59	10	,	,	,
cord-021494-9glqvzfx	59	11	such	such	JJ
cord-021494-9glqvzfx	59	12	that	that	IN
cord-021494-9glqvzfx	59	13	immunohistochemical	immunohistochemical	JJ
cord-021494-9glqvzfx	59	14	data	data	NN
cord-021494-9glqvzfx	59	15	support	support	NN
cord-021494-9glqvzfx	59	16	or	or	CC
cord-021494-9glqvzfx	59	17	fail	fail	VBP
cord-021494-9glqvzfx	59	18	to	to	TO
cord-021494-9glqvzfx	59	19	support	support	VB
cord-021494-9glqvzfx	59	20	the	the	DT
cord-021494-9glqvzfx	59	21	H&E	H&E	NNP
cord-021494-9glqvzfx	59	22	findings	finding	NNS
cord-021494-9glqvzfx	59	23	,	,	,
cord-021494-9glqvzfx	59	24	not	not	RB
cord-021494-9glqvzfx	59	25	vice	vice	RB
cord-021494-9glqvzfx	59	26	versa	versa	RB
cord-021494-9glqvzfx	59	27	.	.	.
cord-021494-9glqvzfx	60	1	Probability	probability	NN
cord-021494-9glqvzfx	60	2	and	and	CC
cord-021494-9glqvzfx	60	3	statistics	statistic	NNS
cord-021494-9glqvzfx	60	4	are	be	VBP
cord-021494-9glqvzfx	60	5	regular	regular	JJ
cord-021494-9glqvzfx	60	6	considerations	consideration	NNS
cord-021494-9glqvzfx	60	7	in	in	IN
cord-021494-9glqvzfx	60	8	immunohistochemical	immunohistochemical	JJ
cord-021494-9glqvzfx	60	9	interpretation	interpretation	NN
cord-021494-9glqvzfx	60	10	,	,	,
cord-021494-9glqvzfx	60	11	since	since	IN
cord-021494-9glqvzfx	60	12	very	very	RB
cord-021494-9glqvzfx	60	13	few	few	JJ
cord-021494-9glqvzfx	60	14	antigens	antigen	NNS
cord-021494-9glqvzfx	60	15	are	be	VBP
cord-021494-9glqvzfx	60	16	tissue	tissue	NN
cord-021494-9glqvzfx	60	17	-	-	HYPH
cord-021494-9glqvzfx	60	18	specific	specific	JJ
cord-021494-9glqvzfx	60	19	or	or	CC
cord-021494-9glqvzfx	60	20	lineage	lineage	NN
cord-021494-9glqvzfx	60	21	-	-	HYPH
cord-021494-9glqvzfx	60	22	specific	specific	JJ
cord-021494-9glqvzfx	60	23	.	.	.
cord-021494-9glqvzfx	61	1	Cytokeratin	Cytokeratin	NNP
cord-021494-9glqvzfx	61	2	is	be	VBZ
cord-021494-9glqvzfx	61	3	positive	positive	JJ
cord-021494-9glqvzfx	61	4	in	in	IN
cord-021494-9glqvzfx	61	5	carcinomas	carcinoma	NNS
cord-021494-9glqvzfx	61	6	,	,	,
cord-021494-9glqvzfx	61	7	but	but	CC
cord-021494-9glqvzfx	61	8	also	also	RB
cord-021494-9glqvzfx	61	9	in	in	IN
cord-021494-9glqvzfx	61	10	synovial	synovial	JJ
cord-021494-9glqvzfx	61	11	and	and	CC
cord-021494-9glqvzfx	61	12	epithelioid	epithelioid	JJ
cord-021494-9glqvzfx	61	13	sarcomas	sarcoma	NNS
cord-021494-9glqvzfx	61	14	.	.	.
cord-021494-9glqvzfx	62	1	This	this	DT
cord-021494-9glqvzfx	62	2	example	example	NN
cord-021494-9glqvzfx	62	3	may	may	MD
cord-021494-9glqvzfx	62	4	imply	imply	VB
cord-021494-9glqvzfx	62	5	aspects	aspect	NNS
cord-021494-9glqvzfx	62	6	of	of	IN
cord-021494-9glqvzfx	62	7	the	the	DT
cord-021494-9glqvzfx	62	8	lineage	lineage	NN
cord-021494-9glqvzfx	62	9	of	of	IN
cord-021494-9glqvzfx	62	10	these	these	DT
cord-021494-9glqvzfx	62	11	two	two	CD
cord-021494-9glqvzfx	62	12	sarcomas	sarcoma	NNS
cord-021494-9glqvzfx	62	13	that	that	WDT
cord-021494-9glqvzfx	62	14	may	may	MD
cord-021494-9glqvzfx	62	15	be	be	VB
cord-021494-9glqvzfx	62	16	helpful	helpful	JJ
cord-021494-9glqvzfx	62	17	in	in	IN
cord-021494-9glqvzfx	62	18	our	-PRON-	PRP$
cord-021494-9glqvzfx	62	19	categorization	categorization	NN
cord-021494-9glqvzfx	62	20	of	of	IN
cord-021494-9glqvzfx	62	21	these	these	DT
cord-021494-9glqvzfx	62	22	neoplasms	neoplasm	NNS
cord-021494-9glqvzfx	62	23	.	.	.
cord-021494-9glqvzfx	63	1	Another	another	DT
cord-021494-9glqvzfx	63	2	example	example	NN
cord-021494-9glqvzfx	63	3	would	would	MD
cord-021494-9glqvzfx	63	4	be	be	VB
cord-021494-9glqvzfx	63	5	the	the	DT
cord-021494-9glqvzfx	63	6	diagnosis	diagnosis	NN
cord-021494-9glqvzfx	63	7	of	of	IN
cord-021494-9glqvzfx	63	8	small	small	JJ
cord-021494-9glqvzfx	63	9	cell	cell	NN
cord-021494-9glqvzfx	63	10	carcinoma	carcinoma	NN
cord-021494-9glqvzfx	63	11	in	in	IN
cord-021494-9glqvzfx	63	12	the	the	DT
cord-021494-9glqvzfx	63	13	lung	lung	NN
cord-021494-9glqvzfx	63	14	of	of	IN
cord-021494-9glqvzfx	63	15	a	a	DT
cord-021494-9glqvzfx	63	16	nonsmoker	nonsmoker	NN
cord-021494-9glqvzfx	63	17	.	.	.
cord-021494-9glqvzfx	64	1	Because	because	IN
cord-021494-9glqvzfx	64	2	lung	lung	NN
cord-021494-9glqvzfx	64	3	primary	primary	JJ
cord-021494-9glqvzfx	64	4	small	small	JJ
cord-021494-9glqvzfx	64	5	cell	cell	NN
cord-021494-9glqvzfx	64	6	carcinoma	carcinoma	NN
cord-021494-9glqvzfx	64	7	is	be	VBZ
cord-021494-9glqvzfx	64	8	extremely	extremely	RB
cord-021494-9glqvzfx	64	9	uncommon	uncommon	JJ
cord-021494-9glqvzfx	64	10	,	,	,
cord-021494-9glqvzfx	64	11	in	in	IN
cord-021494-9glqvzfx	64	12	non	non	NNS
cord-021494-9glqvzfx	64	13	-	-	NNS
cord-021494-9glqvzfx	64	14	smokers	smoker	NNS
cord-021494-9glqvzfx	64	15	,	,	,
cord-021494-9glqvzfx	64	16	this	this	DT
cord-021494-9glqvzfx	64	17	diagnosis	diagnosis	NN
cord-021494-9glqvzfx	64	18	would	would	MD
cord-021494-9glqvzfx	64	19	prompt	prompt	VB
cord-021494-9glqvzfx	64	20	the	the	DT
cord-021494-9glqvzfx	64	21	pathologist	pathologist	NN
cord-021494-9glqvzfx	64	22	to	to	TO
cord-021494-9glqvzfx	64	23	inquire	inquire	VB
cord-021494-9glqvzfx	64	24	about	about	IN
cord-021494-9glqvzfx	64	25	screening	screening	NN
cord-021494-9glqvzfx	64	26	results	result	NNS
cord-021494-9glqvzfx	64	27	for	for	IN
cord-021494-9glqvzfx	64	28	other	other	JJ
cord-021494-9glqvzfx	64	29	,	,	,
cord-021494-9glqvzfx	64	30	nonpulmonary	nonpulmonary	JJ
cord-021494-9glqvzfx	64	31	,	,	,
cord-021494-9glqvzfx	64	32	primary	primary	JJ
cord-021494-9glqvzfx	64	33	sites	site	NNS
cord-021494-9glqvzfx	64	34	.	.	.
cord-021494-9glqvzfx	65	1	Likewise	likewise	RB
cord-021494-9glqvzfx	65	2	,	,	,
cord-021494-9glqvzfx	65	3	immunohistochemistry	immunohistochemistry	NN
cord-021494-9glqvzfx	65	4	results	result	NNS
cord-021494-9glqvzfx	65	5	are	be	VBP
cord-021494-9glqvzfx	65	6	always	always	RB
cord-021494-9glqvzfx	65	7	put	put	VBN
cord-021494-9glqvzfx	65	8	into	into	IN
cord-021494-9glqvzfx	65	9	the	the	DT
cord-021494-9glqvzfx	65	10	context	context	NN
cord-021494-9glqvzfx	65	11	of	of	IN
cord-021494-9glqvzfx	65	12	the	the	DT
cord-021494-9glqvzfx	65	13	morphologic	morphologic	JJ
cord-021494-9glqvzfx	65	14	,	,	,
cord-021494-9glqvzfx	65	15	clinical	clinical	JJ
cord-021494-9glqvzfx	65	16	,	,	,
cord-021494-9glqvzfx	65	17	and	and	CC
cord-021494-9glqvzfx	65	18	radiographic	radiographic	JJ
cord-021494-9glqvzfx	65	19	findings	finding	NNS
cord-021494-9glqvzfx	65	20	.	.	.
cord-021494-9glqvzfx	66	1	For	for	IN
cord-021494-9glqvzfx	66	2	example	example	NN
cord-021494-9glqvzfx	66	3	,	,	,
cord-021494-9glqvzfx	66	4	an	an	DT
cord-021494-9glqvzfx	66	5	undifferentiated	undifferentiated	JJ
cord-021494-9glqvzfx	66	6	CD30(þ	CD30(þ	NNP
cord-021494-9glqvzfx	66	7	)	)	-RRB-
cord-021494-9glqvzfx	66	8	neoplasm	neoplasm	NN
cord-021494-9glqvzfx	66	9	of	of	IN
cord-021494-9glqvzfx	66	10	the	the	DT
cord-021494-9glqvzfx	66	11	testis	testis	NN
cord-021494-9glqvzfx	66	12	supports	support	VBZ
cord-021494-9glqvzfx	66	13	embryonal	embryonal	JJ
cord-021494-9glqvzfx	66	14	carcinoma	carcinoma	NN
cord-021494-9glqvzfx	66	15	primary	primary	NN
cord-021494-9glqvzfx	66	16	in	in	IN
cord-021494-9glqvzfx	66	17	the	the	DT
cord-021494-9glqvzfx	66	18	testis	testis	NN
cord-021494-9glqvzfx	66	19	,	,	,
cord-021494-9glqvzfx	66	20	whereas	whereas	IN
cord-021494-9glqvzfx	66	21	a	a	DT
cord-021494-9glqvzfx	66	22	lymph	lymph	NN
cord-021494-9glqvzfx	66	23	node	node	NN
cord-021494-9glqvzfx	66	24	effaced	efface	VBN
cord-021494-9glqvzfx	66	25	by	by	IN
cord-021494-9glqvzfx	66	26	sclerotic	sclerotic	JJ
cord-021494-9glqvzfx	66	27	bands	band	NNS
cord-021494-9glqvzfx	66	28	with	with	IN
cord-021494-9glqvzfx	66	29	admixed	admix	VBN
cord-021494-9glqvzfx	66	30	CD30(þ	CD30(þ	NNP
cord-021494-9glqvzfx	66	31	)	)	-RRB-
cord-021494-9glqvzfx	67	1	Reed	Reed	NNP
cord-021494-9glqvzfx	67	2	-	-	HYPH
cord-021494-9glqvzfx	67	3	Sternberg	Sternberg	NNP
cord-021494-9glqvzfx	67	4	cells	cell	NNS
cord-021494-9glqvzfx	67	5	supports	support	VBZ
cord-021494-9glqvzfx	67	6	nodular	nodular	JJ
cord-021494-9glqvzfx	67	7	sclerosing	sclerose	VBG
cord-021494-9glqvzfx	67	8	Hodgkin	Hodgkin	NNP
cord-021494-9glqvzfx	67	9	's	's	POS
cord-021494-9glqvzfx	67	10	disease	disease	NN
cord-021494-9glqvzfx	67	11	.	.	.
cord-021494-9glqvzfx	68	1	A	a	DT
cord-021494-9glqvzfx	68	2	wealth	wealth	NN
cord-021494-9glqvzfx	68	3	of	of	IN
cord-021494-9glqvzfx	68	4	information	information	NN
cord-021494-9glqvzfx	68	5	is	be	VBZ
cord-021494-9glqvzfx	68	6	conveyed	convey	VBN
cord-021494-9glqvzfx	68	7	to	to	IN
cord-021494-9glqvzfx	68	8	a	a	DT
cord-021494-9glqvzfx	68	9	service	service	NN
cord-021494-9glqvzfx	68	10	pathologist	pathologist	NN
cord-021494-9glqvzfx	68	11	in	in	IN
cord-021494-9glqvzfx	68	12	a	a	DT
cord-021494-9glqvzfx	68	13	tried	try	VBN
cord-021494-9glqvzfx	68	14	-	-	HYPH
cord-021494-9glqvzfx	68	15	and	and	CC
cord-021494-9glqvzfx	68	16	-	-	HYPH
cord-021494-9glqvzfx	68	17	true	true	JJ
cord-021494-9glqvzfx	68	18	H&E	H&E	NNP
cord-021494-9glqvzfx	68	19	section	section	NN
cord-021494-9glqvzfx	68	20	.	.	.
cord-021494-9glqvzfx	69	1	Analogous	analogous	JJ
cord-021494-9glqvzfx	69	2	to	to	IN
cord-021494-9glqvzfx	69	3	the	the	DT
cord-021494-9glqvzfx	69	4	fact	fact	NN
cord-021494-9glqvzfx	69	5	that	that	IN
cord-021494-9glqvzfx	69	6	a	a	DT
cord-021494-9glqvzfx	69	7	plain	plain	JJ
cord-021494-9glqvzfx	69	8	chest	chest	NN
cord-021494-9glqvzfx	69	9	X	x	NN
cord-021494-9glqvzfx	69	10	-	-	NN
cord-021494-9glqvzfx	69	11	ray	ray	NN
cord-021494-9glqvzfx	69	12	is	be	VBZ
cord-021494-9glqvzfx	69	13	the	the	DT
cord-021494-9glqvzfx	69	14	sum	sum	NN
cord-021494-9glqvzfx	69	15	total	total	NN
cord-021494-9glqvzfx	69	16	of	of	IN
cord-021494-9glqvzfx	69	17	all	all	DT
cord-021494-9glqvzfx	69	18	densities	density	NNS
cord-021494-9glqvzfx	69	19	in	in	IN
cord-021494-9glqvzfx	69	20	the	the	DT
cord-021494-9glqvzfx	69	21	beam	beam	NN
cord-021494-9glqvzfx	69	22	path	path	NN
cord-021494-9glqvzfx	69	23	,	,	,
cord-021494-9glqvzfx	69	24	the	the	DT
cord-021494-9glqvzfx	69	25	morphologic	morphologic	JJ
cord-021494-9glqvzfx	69	26	changes	change	NNS
cord-021494-9glqvzfx	69	27	in	in	IN
cord-021494-9glqvzfx	69	28	diseased	diseased	JJ
cord-021494-9glqvzfx	69	29	cells	cell	NNS
cord-021494-9glqvzfx	69	30	and	and	CC
cord-021494-9glqvzfx	69	31	tissues	tissue	NNS
cord-021494-9glqvzfx	69	32	are	be	VBP
cord-021494-9glqvzfx	69	33	the	the	DT
cord-021494-9glqvzfx	69	34	morphologic	morphologic	JJ
cord-021494-9glqvzfx	69	35	sum	sum	NN
cord-021494-9glqvzfx	69	36	total	total	NN
cord-021494-9glqvzfx	69	37	of	of	IN
cord-021494-9glqvzfx	69	38	all	all	DT
cord-021494-9glqvzfx	69	39	of	of	IN
cord-021494-9glqvzfx	69	40	the	the	DT
cord-021494-9glqvzfx	69	41	disequilibria	disequilibria	NNP
cord-021494-9glqvzfx	69	42	in	in	IN
cord-021494-9glqvzfx	69	43	the	the	DT
cord-021494-9glqvzfx	69	44	abnormal	abnormal	JJ
cord-021494-9glqvzfx	69	45	cells	cell	NNS
cord-021494-9glqvzfx	69	46	.	.	.
cord-021494-9glqvzfx	70	1	For	for	IN
cord-021494-9glqvzfx	70	2	most	most	JJS
cord-021494-9glqvzfx	70	3	neoplastic	neoplastic	JJ
cord-021494-9glqvzfx	70	4	diseases	disease	NNS
cord-021494-9glqvzfx	70	5	,	,	,
cord-021494-9glqvzfx	70	6	morphologic	morphologic	JJ
cord-021494-9glqvzfx	70	7	criteria	criterion	NNS
cord-021494-9glqvzfx	70	8	are	be	VBP
cord-021494-9glqvzfx	70	9	sufficient	sufficient	JJ
cord-021494-9glqvzfx	70	10	to	to	TO
cord-021494-9glqvzfx	70	11	predict	predict	VB
cord-021494-9glqvzfx	70	12	the	the	DT
cord-021494-9glqvzfx	70	13	risk	risk	NN
cord-021494-9glqvzfx	70	14	of	of	IN
cord-021494-9glqvzfx	70	15	invasion	invasion	NN
cord-021494-9glqvzfx	70	16	and	and	CC
cord-021494-9glqvzfx	70	17	metastasis	metastasis	NN
cord-021494-9glqvzfx	70	18	(	(	-LRB-
cord-021494-9glqvzfx	70	19	the	the	DT
cord-021494-9glqvzfx	70	20	malignant	malignant	JJ
cord-021494-9glqvzfx	70	21	potential	potential	NN
cord-021494-9glqvzfx	70	22	)	)	-RRB-
cord-021494-9glqvzfx	70	23	,	,	,
cord-021494-9glqvzfx	70	24	the	the	DT
cord-021494-9glqvzfx	70	25	pattern	pattern	NN
cord-021494-9glqvzfx	70	26	of	of	IN
cord-021494-9glqvzfx	70	27	metastases	metastasis	NNS
cord-021494-9glqvzfx	70	28	,	,	,
cord-021494-9glqvzfx	70	29	and	and	CC
cord-021494-9glqvzfx	70	30	the	the	DT
cord-021494-9glqvzfx	70	31	likely	likely	JJ
cord-021494-9glqvzfx	70	32	clinical	clinical	JJ
cord-021494-9glqvzfx	70	33	outcomes	outcome	NNS
cord-021494-9glqvzfx	70	34	.	.	.
cord-021494-9glqvzfx	71	1	For	for	IN
cord-021494-9glqvzfx	71	2	example	example	NN
cord-021494-9glqvzfx	71	3	,	,	,
cord-021494-9glqvzfx	71	4	the	the	DT
cord-021494-9glqvzfx	71	5	etiology	etiology	NN
cord-021494-9glqvzfx	71	6	and	and	CC
cord-021494-9glqvzfx	71	7	pathogenesis	pathogenesis	NN
cord-021494-9glqvzfx	71	8	in	in	IN
cord-021494-9glqvzfx	71	9	small	small	JJ
cord-021494-9glqvzfx	71	10	cell	cell	NN
cord-021494-9glqvzfx	71	11	lung	lung	NN
cord-021494-9glqvzfx	71	12	carcinoma	carcinoma	NN
cord-021494-9glqvzfx	71	13	can	can	MD
cord-021494-9glqvzfx	71	14	be	be	VB
cord-021494-9glqvzfx	71	15	inferred	infer	VBN
cord-021494-9glqvzfx	71	16	(	(	-LRB-
cord-021494-9glqvzfx	71	17	cigarette	cigarette	NN
cord-021494-9glqvzfx	71	18	smoking	smoking	NN
cord-021494-9glqvzfx	71	19	,	,	,
cord-021494-9glqvzfx	71	20	with	with	IN
cord-021494-9glqvzfx	71	21	carcinogeninduced	carcinogeninduce	VBN
cord-021494-9glqvzfx	71	22	genetic	genetic	JJ
cord-021494-9glqvzfx	71	23	mutations	mutation	NNS
cord-021494-9glqvzfx	71	24	)	)	-RRB-
cord-021494-9glqvzfx	71	25	and	and	CC
cord-021494-9glqvzfx	71	26	the	the	DT
cord-021494-9glqvzfx	71	27	outcome	outcome	NN
cord-021494-9glqvzfx	71	28	predicted	predict	VBD
cord-021494-9glqvzfx	71	29	(	(	-LRB-
cord-021494-9glqvzfx	71	30	early	early	JJ
cord-021494-9glqvzfx	71	31	metastasis	metastasis	NN
cord-021494-9glqvzfx	71	32	to	to	IN
cord-021494-9glqvzfx	71	33	regional	regional	JJ
cord-021494-9glqvzfx	71	34	nodes	node	NNS
cord-021494-9glqvzfx	71	35	and	and	CC
cord-021494-9glqvzfx	71	36	distant	distant	JJ
cord-021494-9glqvzfx	71	37	organs	organ	NNS
cord-021494-9glqvzfx	71	38	,	,	,
cord-021494-9glqvzfx	71	39	with	with	IN
cord-021494-9glqvzfx	71	40	high	high	JJ
cord-021494-9glqvzfx	71	41	probability	probability	NN
cord-021494-9glqvzfx	71	42	of	of	IN
cord-021494-9glqvzfx	71	43	death	death	NN
cord-021494-9glqvzfx	71	44	within	within	IN
cord-021494-9glqvzfx	71	45	5	5	CD
cord-021494-9glqvzfx	71	46	years	year	NNS
cord-021494-9glqvzfx	71	47	of	of	IN
cord-021494-9glqvzfx	71	48	diagnosis	diagnosis	NN
cord-021494-9glqvzfx	71	49	)	)	-RRB-
cord-021494-9glqvzfx	71	50	.	.	.
cord-021494-9glqvzfx	72	1	New	new	JJ
cord-021494-9glqvzfx	72	2	molecular	molecular	JJ
cord-021494-9glqvzfx	72	3	data	datum	NNS
cord-021494-9glqvzfx	72	4	for	for	IN
cord-021494-9glqvzfx	72	5	both	both	CC
cord-021494-9glqvzfx	72	6	neoplastic	neoplastic	JJ
cord-021494-9glqvzfx	72	7	and	and	CC
cord-021494-9glqvzfx	72	8	non	non	JJ
cord-021494-9glqvzfx	72	9	-	-	JJ
cord-021494-9glqvzfx	72	10	neoplastic	neoplastic	JJ
cord-021494-9glqvzfx	72	11	diseases	disease	NNS
cord-021494-9glqvzfx	72	12	will	will	MD
cord-021494-9glqvzfx	72	13	most	most	RBS
cord-021494-9glqvzfx	72	14	likely	likely	RB
cord-021494-9glqvzfx	72	15	benefit	benefit	VB
cord-021494-9glqvzfx	72	16	unaffected	unaffected	JJ
cord-021494-9glqvzfx	72	17	individuals	individual	NNS
cord-021494-9glqvzfx	72	18	by	by	IN
cord-021494-9glqvzfx	72	19	estimating	estimate	VBG
cord-021494-9glqvzfx	72	20	disease	disease	NN
cord-021494-9glqvzfx	72	21	risk	risk	NN
cord-021494-9glqvzfx	72	22	,	,	,
cord-021494-9glqvzfx	72	23	and	and	CC
cord-021494-9glqvzfx	72	24	will	will	MD
cord-021494-9glqvzfx	72	25	most	most	RBS
cord-021494-9glqvzfx	72	26	likely	likely	JJ
cord-021494-9glqvzfx	72	27	benefit	benefit	VB
cord-021494-9glqvzfx	72	28	patients	patient	NNS
cord-021494-9glqvzfx	72	29	by	by	IN
cord-021494-9glqvzfx	72	30	defining	define	VBG
cord-021494-9glqvzfx	72	31	the	the	DT
cord-021494-9glqvzfx	72	32	molecular	molecular	JJ
cord-021494-9glqvzfx	72	33	subset	subset	VBN
cord-021494-9glqvzfx	72	34	for	for	IN
cord-021494-9glqvzfx	72	35	morphologically	morphologically	RB
cord-021494-9glqvzfx	72	36	defined	define	VBN
cord-021494-9glqvzfx	72	37	diagnostic	diagnostic	JJ
cord-021494-9glqvzfx	72	38	entities	entity	NNS
cord-021494-9glqvzfx	72	39	,	,	,
cord-021494-9glqvzfx	72	40	thus	thus	RB
cord-021494-9glqvzfx	72	41	guiding	guide	VBG
cord-021494-9glqvzfx	72	42	individualized	individualized	JJ
cord-021494-9glqvzfx	72	43	therapy	therapy	NN
cord-021494-9glqvzfx	72	44	.	.	.
cord-021494-9glqvzfx	73	1	Diagnostic	diagnostic	JJ
cord-021494-9glqvzfx	73	2	pathology	pathology	NN
cord-021494-9glqvzfx	73	3	will	will	MD
cord-021494-9glqvzfx	73	4	continue	continue	VB
cord-021494-9glqvzfx	73	5	to	to	TO
cord-021494-9glqvzfx	73	6	use	use	VB
cord-021494-9glqvzfx	73	7	morphology	morphology	NN
cord-021494-9glqvzfx	73	8	and	and	CC
cord-021494-9glqvzfx	73	9	complementary	complementary	JJ
cord-021494-9glqvzfx	73	10	data	datum	NNS
cord-021494-9glqvzfx	73	11	from	from	IN
cord-021494-9glqvzfx	73	12	protein	protein	NN
cord-021494-9glqvzfx	73	13	(	(	-LRB-
cord-021494-9glqvzfx	73	14	immunohistochemical	immunohistochemical	JJ
cord-021494-9glqvzfx	73	15	)	)	-RRB-
cord-021494-9glqvzfx	73	16	and	and	CC
cord-021494-9glqvzfx	73	17	nucleic	nucleic	JJ
cord-021494-9glqvzfx	73	18	acid	acid	NN
cord-021494-9glqvzfx	73	19	(	(	-LRB-
cord-021494-9glqvzfx	73	20	cytogenetics	cytogenetic	NNS
cord-021494-9glqvzfx	73	21	,	,	,
cord-021494-9glqvzfx	73	22	in	in	IN
cord-021494-9glqvzfx	73	23	situ	situ	NN
cord-021494-9glqvzfx	73	24	hybridization	hybridization	NN
cord-021494-9glqvzfx	73	25	,	,	,
cord-021494-9glqvzfx	73	26	DNA	dna	NN
cord-021494-9glqvzfx	73	27	sequence	sequence	NN
cord-021494-9glqvzfx	73	28	,	,	,
cord-021494-9glqvzfx	73	29	and	and	CC
cord-021494-9glqvzfx	73	30	RNA	RNA	NNP
cord-021494-9glqvzfx	73	31	abundance	abundance	NN
cord-021494-9glqvzfx	74	1	)	)	-RRB-
cord-021494-9glqvzfx	74	2	screening	screening	NN
cord-021494-9glqvzfx	74	3	assays	assay	NNS
cord-021494-9glqvzfx	74	4	.	.	.
cord-021494-9glqvzfx	75	1	New	new	JJ
cord-021494-9glqvzfx	75	2	data	datum	NNS
cord-021494-9glqvzfx	75	3	will	will	MD
cord-021494-9glqvzfx	75	4	be	be	VB
cord-021494-9glqvzfx	75	5	integrated	integrate	VBN
cord-021494-9glqvzfx	75	6	into	into	IN
cord-021494-9glqvzfx	75	7	the	the	DT
cord-021494-9glqvzfx	75	8	diagnostic	diagnostic	JJ
cord-021494-9glqvzfx	75	9	process	process	NN
cord-021494-9glqvzfx	75	10	by	by	IN
cord-021494-9glqvzfx	75	11	reducing	reduce	VBG
cord-021494-9glqvzfx	75	12	the	the	DT
cord-021494-9glqvzfx	75	13	cost	cost	NN
cord-021494-9glqvzfx	75	14	and	and	CC
cord-021494-9glqvzfx	75	15	turnaround	turnaround	NN
cord-021494-9glqvzfx	75	16	time	time	NN
cord-021494-9glqvzfx	75	17	of	of	IN
cord-021494-9glqvzfx	75	18	current	current	JJ
cord-021494-9glqvzfx	75	19	technologies	technology	NNS
cord-021494-9glqvzfx	75	20	,	,	,
cord-021494-9glqvzfx	75	21	and	and	CC
cord-021494-9glqvzfx	75	22	by	by	IN
cord-021494-9glqvzfx	75	23	development	development	NN
cord-021494-9glqvzfx	75	24	of	of	IN
cord-021494-9glqvzfx	75	25	new	new	JJ
cord-021494-9glqvzfx	75	26	technologies	technology	NNS
cord-021494-9glqvzfx	75	27	,	,	,
cord-021494-9glqvzfx	75	28	some	some	DT
cord-021494-9glqvzfx	75	29	of	of	IN
cord-021494-9glqvzfx	75	30	which	which	WDT
cord-021494-9glqvzfx	75	31	are	be	VBP
cord-021494-9glqvzfx	75	32	described	describe	VBN
cord-021494-9glqvzfx	75	33	.	.	.
cord-021494-9glqvzfx	76	1	For	for	IN
cord-021494-9glqvzfx	76	2	transplant	transplant	NN
cord-021494-9glqvzfx	76	3	candidates	candidate	NNS
cord-021494-9glqvzfx	76	4	,	,	,
cord-021494-9glqvzfx	76	5	major	major	JJ
cord-021494-9glqvzfx	76	6	histocompatibility	histocompatibility	NN
cord-021494-9glqvzfx	76	7	complex	complex	NN
cord-021494-9glqvzfx	76	8	(	(	-LRB-
cord-021494-9glqvzfx	76	9	MHC	MHC	NNP
cord-021494-9glqvzfx	76	10	,	,	,
cord-021494-9glqvzfx	76	11	HLA	HLA	NNP
cord-021494-9glqvzfx	76	12	in	in	IN
cord-021494-9glqvzfx	76	13	human	human	JJ
cord-021494-9glqvzfx	76	14	)	)	-RRB-
cord-021494-9glqvzfx	76	15	screening	screening	NN
cord-021494-9glqvzfx	76	16	is	be	VBZ
cord-021494-9glqvzfx	76	17	evolving	evolve	VBG
cord-021494-9glqvzfx	76	18	from	from	IN
cord-021494-9glqvzfx	76	19	cellular	cellular	JJ
cord-021494-9glqvzfx	76	20	assays	assay	NNS
cord-021494-9glqvzfx	76	21	and	and	CC
cord-021494-9glqvzfx	76	22	serology	serology	NN
cord-021494-9glqvzfx	76	23	toward	toward	IN
cord-021494-9glqvzfx	76	24	sequencing	sequencing	NN
cord-021494-9glqvzfx	76	25	of	of	IN
cord-021494-9glqvzfx	76	26	the	the	DT
cord-021494-9glqvzfx	76	27	alleles	allele	NNS
cord-021494-9glqvzfx	76	28	of	of	IN
cord-021494-9glqvzfx	76	29	the	the	DT
cord-021494-9glqvzfx	76	30	class	class	NN
cord-021494-9glqvzfx	76	31	I	i	NN
cord-021494-9glqvzfx	76	32	and	and	CC
cord-021494-9glqvzfx	76	33	II	II	NNP
cord-021494-9glqvzfx	76	34	HLA	HLA	NNP
cord-021494-9glqvzfx	76	35	loci	locus	NNS
cord-021494-9glqvzfx	76	36	.	.	.
cord-021494-9glqvzfx	77	1	Rapid	rapid	JJ
cord-021494-9glqvzfx	77	2	sequencing	sequencing	NN
cord-021494-9glqvzfx	77	3	of	of	IN
cord-021494-9glqvzfx	77	4	these	these	DT
cord-021494-9glqvzfx	77	5	alleles	allele	NNS
cord-021494-9glqvzfx	77	6	in	in	IN
cord-021494-9glqvzfx	77	7	newborn	newborn	JJ
cord-021494-9glqvzfx	77	8	cord	cord	NN
cord-021494-9glqvzfx	77	9	blood	blood	NN
cord-021494-9glqvzfx	77	10	would	would	MD
cord-021494-9glqvzfx	77	11	allow	allow	VB
cord-021494-9glqvzfx	77	12	databasing	databasing	NN
cord-021494-9glqvzfx	77	13	of	of	IN
cord-021494-9glqvzfx	77	14	the	the	DT
cord-021494-9glqvzfx	77	15	population	population	NN
cord-021494-9glqvzfx	77	16	's	's	POS
cord-021494-9glqvzfx	77	17	haplotypes	haplotype	NNS
cord-021494-9glqvzfx	77	18	,	,	,
cord-021494-9glqvzfx	77	19	facilitating	facilitate	VBG
cord-021494-9glqvzfx	77	20	perfect	perfect	JJ
cord-021494-9glqvzfx	77	21	matches	match	NNS
cord-021494-9glqvzfx	77	22	for	for	IN
cord-021494-9glqvzfx	77	23	required	require	VBN
cord-021494-9glqvzfx	77	24	bone	bone	NN
cord-021494-9glqvzfx	77	25	marrow	marrow	NN
cord-021494-9glqvzfx	77	26	or	or	CC
cord-021494-9glqvzfx	77	27	solid	solid	JJ
cord-021494-9glqvzfx	77	28	organ	organ	NN
cord-021494-9glqvzfx	77	29	transplants	transplant	NNS
cord-021494-9glqvzfx	77	30	.	.	.
cord-021494-9glqvzfx	78	1	Current	current	JJ
cord-021494-9glqvzfx	78	2	uses	use	NNS
cord-021494-9glqvzfx	78	3	of	of	IN
cord-021494-9glqvzfx	78	4	in	in	IN
cord-021494-9glqvzfx	78	5	situ	situ	JJ
cord-021494-9glqvzfx	78	6	hybridization	hybridization	NN
cord-021494-9glqvzfx	78	7	to	to	TO
cord-021494-9glqvzfx	78	8	screen	screen	VB
cord-021494-9glqvzfx	78	9	for	for	IN
cord-021494-9glqvzfx	78	10	viruses	virus	NNS
cord-021494-9glqvzfx	78	11	(	(	-LRB-
cord-021494-9glqvzfx	78	12	such	such	JJ
cord-021494-9glqvzfx	78	13	as	as	IN
cord-021494-9glqvzfx	78	14	EBV	EBV	NNP
cord-021494-9glqvzfx	78	15	)	)	-RRB-
cord-021494-9glqvzfx	79	1	,	,	,
cord-021494-9glqvzfx	79	2	light	light	JJ
cord-021494-9glqvzfx	79	3	chain	chain	NN
cord-021494-9glqvzfx	79	4	restriction	restriction	NN
cord-021494-9glqvzfx	79	5	(	(	-LRB-
cord-021494-9glqvzfx	79	6	in	in	IN
cord-021494-9glqvzfx	79	7	B	b	NN
cord-021494-9glqvzfx	79	8	lymphomas	lymphoma	NNS
cord-021494-9glqvzfx	79	9	)	)	-RRB-
cord-021494-9glqvzfx	79	10	,	,	,
cord-021494-9glqvzfx	79	11	and	and	CC
cord-021494-9glqvzfx	79	12	copy	copy	NN
cord-021494-9glqvzfx	79	13	number	number	NN
cord-021494-9glqvzfx	79	14	variation	variation	NN
cord-021494-9glqvzfx	79	15	(	(	-LRB-
cord-021494-9glqvzfx	79	16	for	for	IN
cord-021494-9glqvzfx	79	17	instance	instance	NN
cord-021494-9glqvzfx	79	18	,	,	,
cord-021494-9glqvzfx	79	19	HER2	HER2	NNP
cord-021494-9glqvzfx	79	20	gene	gene	NN
cord-021494-9glqvzfx	79	21	amplification	amplification	NN
cord-021494-9glqvzfx	79	22	)	)	-RRB-
cord-021494-9glqvzfx	79	23	demonstrate	demonstrate	VBP
cord-021494-9glqvzfx	79	24	the	the	DT
cord-021494-9glqvzfx	79	25	benefit	benefit	NN
cord-021494-9glqvzfx	79	26	of	of	IN
cord-021494-9glqvzfx	79	27	in	in	IN
cord-021494-9glqvzfx	79	28	situ	situ	JJ
cord-021494-9glqvzfx	79	29	nucleic	nucleic	JJ
cord-021494-9glqvzfx	79	30	acid	acid	NN
cord-021494-9glqvzfx	79	31	hybridization	hybridization	NN
cord-021494-9glqvzfx	79	32	assays	assay	NNS
cord-021494-9glqvzfx	79	33	.	.	.
cord-021494-9glqvzfx	80	1	It	-PRON-	PRP
cord-021494-9glqvzfx	80	2	is	be	VBZ
cord-021494-9glqvzfx	80	3	possible	possible	JJ
cord-021494-9glqvzfx	80	4	that	that	IN
cord-021494-9glqvzfx	80	5	interphase	interphase	NN
cord-021494-9glqvzfx	80	6	FISH	fish	NN
cord-021494-9glqvzfx	80	7	/	/	SYM
cord-021494-9glqvzfx	80	8	CISH	CISH	NNP
cord-021494-9glqvzfx	80	9	will	will	MD
cord-021494-9glqvzfx	80	10	become	become	VB
cord-021494-9glqvzfx	80	11	rapid	rapid	JJ
cord-021494-9glqvzfx	80	12	enough	enough	RB
cord-021494-9glqvzfx	80	13	to	to	TO
cord-021494-9glqvzfx	80	14	be	be	VB
cord-021494-9glqvzfx	80	15	used	use	VBN
cord-021494-9glqvzfx	80	16	in	in	IN
cord-021494-9glqvzfx	80	17	the	the	DT
cord-021494-9glqvzfx	80	18	initial	initial	JJ
cord-021494-9glqvzfx	80	19	diagnostic	diagnostic	JJ
cord-021494-9glqvzfx	80	20	workup	workup	NN
cord-021494-9glqvzfx	80	21	of	of	IN
cord-021494-9glqvzfx	80	22	certain	certain	JJ
cord-021494-9glqvzfx	80	23	patients	patient	NNS
cord-021494-9glqvzfx	80	24	,	,	,
cord-021494-9glqvzfx	80	25	including	include	VBG
cord-021494-9glqvzfx	80	26	for	for	IN
cord-021494-9glqvzfx	80	27	sarcomaspecific	sarcomaspecific	NNP
cord-021494-9glqvzfx	80	28	translocations	translocation	NNS
cord-021494-9glqvzfx	80	29	,	,	,
cord-021494-9glqvzfx	80	30	ploidy	ploidy	NN
cord-021494-9glqvzfx	80	31	analysis	analysis	NN
cord-021494-9glqvzfx	80	32	in	in	IN
cord-021494-9glqvzfx	80	33	hydatidiform	hydatidiform	NNP
cord-021494-9glqvzfx	80	34	moles	mole	NNS
cord-021494-9glqvzfx	80	35	,	,	,
cord-021494-9glqvzfx	80	36	and	and	CC
cord-021494-9glqvzfx	80	37	gene	gene	NN
cord-021494-9glqvzfx	80	38	amplification	amplification	NN
cord-021494-9glqvzfx	80	39	of	of	IN
cord-021494-9glqvzfx	80	40	receptor	receptor	NN
cord-021494-9glqvzfx	80	41	tyrosine	tyrosine	NN
cord-021494-9glqvzfx	80	42	kinase	kinase	VBZ
cord-021494-9glqvzfx	80	43	genes	gene	NNS
cord-021494-9glqvzfx	80	44	.	.	.
cord-021494-9glqvzfx	81	1	Current	current	JJ
cord-021494-9glqvzfx	81	2	uses	use	NNS
cord-021494-9glqvzfx	81	3	of	of	IN
cord-021494-9glqvzfx	81	4	nucleic	nucleic	JJ
cord-021494-9glqvzfx	81	5	acid	acid	NN
cord-021494-9glqvzfx	81	6	screening	screening	NN
cord-021494-9glqvzfx	81	7	for	for	IN
cord-021494-9glqvzfx	81	8	bcr	bcr	NNP
cord-021494-9glqvzfx	81	9	-	-	HYPH
cord-021494-9glqvzfx	81	10	abl	abl	NNP
cord-021494-9glqvzfx	81	11	translocation	translocation	NN
cord-021494-9glqvzfx	81	12	,	,	,
cord-021494-9glqvzfx	81	13	donor	donor	NN
cord-021494-9glqvzfx	81	14	:	:	:
cord-021494-9glqvzfx	81	15	recipient	recipient	NN
cord-021494-9glqvzfx	81	16	ratios	ratio	NNS
cord-021494-9glqvzfx	81	17	after	after	IN
cord-021494-9glqvzfx	81	18	bone	bone	NN
cord-021494-9glqvzfx	81	19	marrow	marrow	NN
cord-021494-9glqvzfx	81	20	transplant	transplant	NN
cord-021494-9glqvzfx	81	21	,	,	,
cord-021494-9glqvzfx	81	22	microsatellite	microsatellite	JJ
cord-021494-9glqvzfx	81	23	instability	instability	NN
cord-021494-9glqvzfx	81	24	,	,	,
cord-021494-9glqvzfx	81	25	quantitative	quantitative	JJ
cord-021494-9glqvzfx	81	26	viral	viral	JJ
cord-021494-9glqvzfx	81	27	load	load	NN
cord-021494-9glqvzfx	81	28	(	(	-LRB-
cord-021494-9glqvzfx	81	29	for	for	IN
cord-021494-9glqvzfx	81	30	EBV	EBV	NNP
cord-021494-9glqvzfx	81	31	,	,	,
cord-021494-9glqvzfx	81	32	BK	BK	NNP
cord-021494-9glqvzfx	81	33	,	,	,
cord-021494-9glqvzfx	81	34	CMV	CMV	NNP
cord-021494-9glqvzfx	81	35	,	,	,
cord-021494-9glqvzfx	81	36	and	and	CC
cord-021494-9glqvzfx	81	37	others	other	NNS
cord-021494-9glqvzfx	81	38	)	)	-RRB-
cord-021494-9glqvzfx	81	39	,	,	,
cord-021494-9glqvzfx	81	40	and	and	CC
cord-021494-9glqvzfx	81	41	single	single	JJ
cord-021494-9glqvzfx	81	42	gene	gene	NN
cord-021494-9glqvzfx	81	43	mutations	mutation	NNS
cord-021494-9glqvzfx	81	44	(	(	-LRB-
cord-021494-9glqvzfx	81	45	for	for	IN
cord-021494-9glqvzfx	81	46	CFTR	CFTR	NNP
cord-021494-9glqvzfx	81	47	,	,	,
cord-021494-9glqvzfx	81	48	Factor	factor	NN
cord-021494-9glqvzfx	81	49	2	2	CD
cord-021494-9glqvzfx	81	50	,	,	,
cord-021494-9glqvzfx	81	51	a-1-antitrypsin	a-1-antitrypsin	''
cord-021494-9glqvzfx	81	52	)	)	-RRB-
cord-021494-9glqvzfx	81	53	demonstrate	demonstrate	VBP
cord-021494-9glqvzfx	81	54	the	the	DT
cord-021494-9glqvzfx	81	55	benefit	benefit	NN
cord-021494-9glqvzfx	81	56	of	of	IN
cord-021494-9glqvzfx	81	57	nucleic	nucleic	JJ
cord-021494-9glqvzfx	81	58	acid	acid	NN
cord-021494-9glqvzfx	81	59	screening	screening	NN
cord-021494-9glqvzfx	81	60	in	in	IN
cord-021494-9glqvzfx	81	61	diagnosis	diagnosis	NN
cord-021494-9glqvzfx	81	62	and	and	CC
cord-021494-9glqvzfx	81	63	management	management	NN
cord-021494-9glqvzfx	81	64	.	.	.
cord-021494-9glqvzfx	82	1	It	-PRON-	PRP
cord-021494-9glqvzfx	82	2	is	be	VBZ
cord-021494-9glqvzfx	82	3	possible	possible	JJ
cord-021494-9glqvzfx	82	4	that	that	IN
cord-021494-9glqvzfx	82	5	each	each	DT
cord-021494-9glqvzfx	82	6	new	new	JJ
cord-021494-9glqvzfx	82	7	neoplasm	neoplasm	NN
cord-021494-9glqvzfx	82	8	will	will	MD
cord-021494-9glqvzfx	82	9	be	be	VB
cord-021494-9glqvzfx	82	10	promptly	promptly	RB
cord-021494-9glqvzfx	82	11	defined	define	VBN
cord-021494-9glqvzfx	82	12	as	as	IN
cord-021494-9glqvzfx	82	13	to	to	IN
cord-021494-9glqvzfx	82	14	ploidy	ploidy	NN
cord-021494-9glqvzfx	82	15	,	,	,
cord-021494-9glqvzfx	82	16	translocations	translocation	NNS
cord-021494-9glqvzfx	82	17	,	,	,
cord-021494-9glqvzfx	82	18	gene	gene	NN
cord-021494-9glqvzfx	82	19	copy	copy	NN
cord-021494-9glqvzfx	82	20	number	number	NN
cord-021494-9glqvzfx	82	21	differences	difference	NNS
cord-021494-9glqvzfx	82	22	,	,	,
cord-021494-9glqvzfx	82	23	DNA	dna	NN
cord-021494-9glqvzfx	82	24	mutations	mutation	NNS
cord-021494-9glqvzfx	82	25	,	,	,
cord-021494-9glqvzfx	82	26	and	and	CC
cord-021494-9glqvzfx	82	27	RNA	RNA	NNP
cord-021494-9glqvzfx	82	28	expression	expression	NN
cord-021494-9glqvzfx	82	29	cluster	cluster	NN
cord-021494-9glqvzfx	82	30	subset	subset	VBN
cord-021494-9glqvzfx	82	31	,	,	,
cord-021494-9glqvzfx	82	32	allowing	allow	VBG
cord-021494-9glqvzfx	82	33	residual	residual	JJ
cord-021494-9glqvzfx	82	34	disease	disease	NN
cord-021494-9glqvzfx	82	35	screening	screening	NN
cord-021494-9glqvzfx	82	36	as	as	RB
cord-021494-9glqvzfx	82	37	well	well	RB
cord-021494-9glqvzfx	82	38	as	as	IN
cord-021494-9glqvzfx	82	39	individualized	individualized	JJ
cord-021494-9glqvzfx	82	40	therapy	therapy	NN
cord-021494-9glqvzfx	82	41	.	.	.
cord-021494-9glqvzfx	83	1	Current	current	JJ
cord-021494-9glqvzfx	83	2	uses	use	NNS
cord-021494-9glqvzfx	83	3	of	of	IN
cord-021494-9glqvzfx	83	4	morphology	morphology	NN
cord-021494-9glqvzfx	83	5	,	,	,
cord-021494-9glqvzfx	83	6	immunohistochemistry	immunohistochemistry	NN
cord-021494-9glqvzfx	83	7	,	,	,
cord-021494-9glqvzfx	83	8	and	and	CC
cord-021494-9glqvzfx	83	9	molecular	molecular	JJ
cord-021494-9glqvzfx	83	10	pathology	pathology	NN
cord-021494-9glqvzfx	83	11	demonstrate	demonstrate	VBP
cord-021494-9glqvzfx	83	12	their	-PRON-	PRP$
cord-021494-9glqvzfx	83	13	benefit	benefit	NN
cord-021494-9glqvzfx	83	14	through	through	IN
cord-021494-9glqvzfx	83	15	improved	improve	VBN
cord-021494-9glqvzfx	83	16	diagnostic	diagnostic	JJ
cord-021494-9glqvzfx	83	17	accuracy	accuracy	NN
cord-021494-9glqvzfx	83	18	.	.	.
cord-021494-9glqvzfx	84	1	However	however	RB
cord-021494-9glqvzfx	84	2	,	,	,
cord-021494-9glqvzfx	84	3	diagnosis	diagnosis	NN
cord-021494-9glqvzfx	84	4	,	,	,
cord-021494-9glqvzfx	84	5	extent	extent	NN
cord-021494-9glqvzfx	84	6	of	of	IN
cord-021494-9glqvzfx	84	7	disease	disease	NN
cord-021494-9glqvzfx	84	8	,	,	,
cord-021494-9glqvzfx	84	9	and	and	CC
cord-021494-9glqvzfx	84	10	molecular	molecular	JJ
cord-021494-9glqvzfx	84	11	subsets	subset	NNS
cord-021494-9glqvzfx	84	12	are	be	VBP
cord-021494-9glqvzfx	84	13	currently	currently	RB
cord-021494-9glqvzfx	84	14	imperfect	imperfect	JJ
cord-021494-9glqvzfx	84	15	estimators	estimator	NNS
cord-021494-9glqvzfx	84	16	of	of	IN
cord-021494-9glqvzfx	84	17	prognosis	prognosis	NN
cord-021494-9glqvzfx	84	18	and	and	CC
cord-021494-9glqvzfx	84	19	response	response	NN
cord-021494-9glqvzfx	84	20	to	to	IN
cord-021494-9glqvzfx	84	21	therapy	therapy	NN
cord-021494-9glqvzfx	84	22	.	.	.
cord-021494-9glqvzfx	85	1	Relational	relational	JJ
cord-021494-9glqvzfx	85	2	databases	database	NNS
cord-021494-9glqvzfx	85	3	which	which	WDT
cord-021494-9glqvzfx	85	4	correlate	correlate	VBP
cord-021494-9glqvzfx	85	5	an	an	DT
cord-021494-9glqvzfx	85	6	individual	individual	NN
cord-021494-9glqvzfx	85	7	's	's	POS
cord-021494-9glqvzfx	85	8	demographic	demographic	JJ
cord-021494-9glqvzfx	85	9	data	datum	NNS
cord-021494-9glqvzfx	85	10	,	,	,
cord-021494-9glqvzfx	85	11	family	family	NN
cord-021494-9glqvzfx	85	12	history	history	NN
cord-021494-9glqvzfx	85	13	,	,	,
cord-021494-9glqvzfx	85	14	concurrent	concurrent	JJ
cord-021494-9glqvzfx	85	15	diseases	disease	NNS
cord-021494-9glqvzfx	85	16	,	,	,
cord-021494-9glqvzfx	85	17	morphologic	morphologic	JJ
cord-021494-9glqvzfx	85	18	features	feature	NNS
cord-021494-9glqvzfx	85	19	,	,	,
cord-021494-9glqvzfx	85	20	immunophenotype	immunophenotype	NN
cord-021494-9glqvzfx	85	21	,	,	,
cord-021494-9glqvzfx	85	22	and	and	CC
cord-021494-9glqvzfx	85	23	molecular	molecular	JJ
cord-021494-9glqvzfx	85	24	subset	subset	NN
cord-021494-9glqvzfx	85	25	,	,	,
cord-021494-9glqvzfx	85	26	and	and	CC
cord-021494-9glqvzfx	85	27	which	which	WDT
cord-021494-9glqvzfx	85	28	integrate	integrate	VBP
cord-021494-9glqvzfx	85	29	disease	disease	NN
cord-021494-9glqvzfx	85	30	prevalence	prevalence	NN
cord-021494-9glqvzfx	85	31	by	by	IN
cord-021494-9glqvzfx	85	32	age	age	NN
cord-021494-9glqvzfx	85	33	,	,	,
cord-021494-9glqvzfx	85	34	sex	sex	NN
cord-021494-9glqvzfx	85	35	,	,	,
cord-021494-9glqvzfx	85	36	and	and	CC
cord-021494-9glqvzfx	85	37	ethnicity	ethnicity	NN
cord-021494-9glqvzfx	85	38	using	use	VBG
cord-021494-9glqvzfx	85	39	Bayesian	bayesian	JJ
cord-021494-9glqvzfx	85	40	probabilities	probability	NNS
cord-021494-9glqvzfx	85	41	,	,	,
cord-021494-9glqvzfx	85	42	should	should	MD
cord-021494-9glqvzfx	85	43	improve	improve	VB
cord-021494-9glqvzfx	85	44	accuracy	accuracy	NN
cord-021494-9glqvzfx	85	45	of	of	IN
cord-021494-9glqvzfx	85	46	prognosis	prognosis	NN
cord-021494-9glqvzfx	85	47	and	and	CC
cord-021494-9glqvzfx	85	48	prediction	prediction	NN
cord-021494-9glqvzfx	85	49	of	of	IN
cord-021494-9glqvzfx	85	50	response	response	NN
cord-021494-9glqvzfx	85	51	to	to	IN
cord-021494-9glqvzfx	85	52	therapy	therapy	NN
cord-021494-9glqvzfx	85	53	.	.	.
cord-021494-9glqvzfx	86	1	As	as	IN
cord-021494-9glqvzfx	86	2	risk	risk	NN
cord-021494-9glqvzfx	86	3	correlates	correlate	VBZ
cord-021494-9glqvzfx	86	4	are	be	VBP
cord-021494-9glqvzfx	86	5	developed	develop	VBN
cord-021494-9glqvzfx	86	6	,	,	,
cord-021494-9glqvzfx	86	7	it	-PRON-	PRP
cord-021494-9glqvzfx	86	8	is	be	VBZ
cord-021494-9glqvzfx	86	9	possible	possible	JJ
cord-021494-9glqvzfx	86	10	that	that	IN
cord-021494-9glqvzfx	86	11	healthy	healthy	JJ
cord-021494-9glqvzfx	86	12	individuals	individual	NNS
cord-021494-9glqvzfx	86	13	will	will	MD
cord-021494-9glqvzfx	86	14	be	be	VB
cord-021494-9glqvzfx	86	15	screened	screen	VBN
cord-021494-9glqvzfx	86	16	and	and	CC
cord-021494-9glqvzfx	86	17	given	give	VBN
cord-021494-9glqvzfx	86	18	risk	risk	NN
cord-021494-9glqvzfx	86	19	estimates	estimate	NNS
cord-021494-9glqvzfx	86	20	for	for	IN
cord-021494-9glqvzfx	86	21	development	development	NN
cord-021494-9glqvzfx	86	22	of	of	IN
cord-021494-9glqvzfx	86	23	different	different	JJ
cord-021494-9glqvzfx	86	24	diseases	disease	NNS
cord-021494-9glqvzfx	86	25	.	.	.
cord-021494-9glqvzfx	87	1	Current	current	JJ
cord-021494-9glqvzfx	87	2	uses	use	NNS
cord-021494-9glqvzfx	87	3	of	of	IN
cord-021494-9glqvzfx	87	4	normal	normal	JJ
cord-021494-9glqvzfx	87	5	ranges	range	NNS
cord-021494-9glqvzfx	87	6	for	for	IN
cord-021494-9glqvzfx	87	7	serum	serum	NN
cord-021494-9glqvzfx	87	8	chemistry	chemistry	NN
cord-021494-9glqvzfx	87	9	assumes	assume	VBZ
cord-021494-9glqvzfx	87	10	a	a	DT
cord-021494-9glqvzfx	87	11	similar	similar	JJ
cord-021494-9glqvzfx	87	12	bell	bell	NN
cord-021494-9glqvzfx	87	13	-	-	HYPH
cord-021494-9glqvzfx	87	14	curve	curve	NN
cord-021494-9glqvzfx	87	15	distribution	distribution	NN
cord-021494-9glqvzfx	87	16	across	across	IN
cord-021494-9glqvzfx	87	17	ages	age	NNS
cord-021494-9glqvzfx	87	18	,	,	,
cord-021494-9glqvzfx	87	19	sexes	sex	NNS
cord-021494-9glqvzfx	87	20	,	,	,
cord-021494-9glqvzfx	87	21	and	and	CC
cord-021494-9glqvzfx	87	22	races	race	NNS
cord-021494-9glqvzfx	87	23	.	.	.
cord-021494-9glqvzfx	88	1	This	this	DT
cord-021494-9glqvzfx	88	2	may	may	MD
cord-021494-9glqvzfx	88	3	be	be	VB
cord-021494-9glqvzfx	88	4	true	true	JJ
cord-021494-9glqvzfx	88	5	for	for	IN
cord-021494-9glqvzfx	88	6	most	most	JJS
cord-021494-9glqvzfx	88	7	but	but	CC
cord-021494-9glqvzfx	88	8	not	not	RB
cord-021494-9glqvzfx	88	9	all	all	DT
cord-021494-9glqvzfx	88	10	analytes	analyte	NNS
cord-021494-9glqvzfx	88	11	.	.	.
cord-021494-9glqvzfx	89	1	Computer	computer	NN
cord-021494-9glqvzfx	89	2	reference	reference	NN
cord-021494-9glqvzfx	89	3	databases	database	NNS
cord-021494-9glqvzfx	89	4	will	will	MD
cord-021494-9glqvzfx	89	5	likely	likely	RB
cord-021494-9glqvzfx	89	6	generate	generate	VB
cord-021494-9glqvzfx	89	7	normal	normal	JJ
cord-021494-9glqvzfx	89	8	ranges	range	NNS
cord-021494-9glqvzfx	89	9	specific	specific	JJ
cord-021494-9glqvzfx	89	10	for	for	IN
cord-021494-9glqvzfx	89	11	the	the	DT
cord-021494-9glqvzfx	89	12	particular	particular	JJ
cord-021494-9glqvzfx	89	13	age	age	NN
cord-021494-9glqvzfx	89	14	/	/	SYM
cord-021494-9glqvzfx	89	15	sex	sex	NN
cord-021494-9glqvzfx	89	16	/	/	SYM
cord-021494-9glqvzfx	89	17	ethnicity	ethnicity	NN
cord-021494-9glqvzfx	89	18	of	of	IN
cord-021494-9glqvzfx	89	19	individual	individual	JJ
cord-021494-9glqvzfx	89	20	patients	patient	NNS
cord-021494-9glqvzfx	89	21	.	.	.
cord-021494-9glqvzfx	90	1	Similarly	similarly	RB
cord-021494-9glqvzfx	90	2	,	,	,
cord-021494-9glqvzfx	90	3	familial	familial	JJ
cord-021494-9glqvzfx	90	4	risk	risk	NN
cord-021494-9glqvzfx	90	5	for	for	IN
cord-021494-9glqvzfx	90	6	an	an	DT
cord-021494-9glqvzfx	90	7	inherited	inherit	VBN
cord-021494-9glqvzfx	90	8	disease	disease	NN
cord-021494-9glqvzfx	90	9	may	may	MD
cord-021494-9glqvzfx	90	10	vary	vary	VB
cord-021494-9glqvzfx	90	11	by	by	IN
cord-021494-9glqvzfx	90	12	ethnic	ethnic	JJ
cord-021494-9glqvzfx	90	13	group	group	NN
cord-021494-9glqvzfx	90	14	,	,	,
cord-021494-9glqvzfx	90	15	and	and	CC
cord-021494-9glqvzfx	90	16	this	this	DT
cord-021494-9glqvzfx	90	17	variation	variation	NN
cord-021494-9glqvzfx	90	18	should	should	MD
cord-021494-9glqvzfx	90	19	be	be	VB
cord-021494-9glqvzfx	90	20	used	use	VBN
cord-021494-9glqvzfx	90	21	in	in	IN
cord-021494-9glqvzfx	90	22	Bayesian	bayesian	JJ
cord-021494-9glqvzfx	90	23	calculations	calculation	NNS
cord-021494-9glqvzfx	90	24	to	to	TO
cord-021494-9glqvzfx	90	25	define	define	VB
cord-021494-9glqvzfx	90	26	risk	risk	NN
cord-021494-9glqvzfx	90	27	for	for	IN
cord-021494-9glqvzfx	90	28	unaffected	unaffected	JJ
cord-021494-9glqvzfx	90	29	at	at	IN
cord-021494-9glqvzfx	90	30	-	-	HYPH
cord-021494-9glqvzfx	90	31	risk	risk	NN
cord-021494-9glqvzfx	90	32	family	family	NN
cord-021494-9glqvzfx	90	33	members	member	NNS
cord-021494-9glqvzfx	90	34	.	.	.
cord-021494-9glqvzfx	91	1	Current	current	JJ
cord-021494-9glqvzfx	91	2	uses	use	NNS
cord-021494-9glqvzfx	91	3	of	of	IN
cord-021494-9glqvzfx	91	4	liver	liver	NN
cord-021494-9glqvzfx	91	5	and	and	CC
cord-021494-9glqvzfx	91	6	renal	renal	JJ
cord-021494-9glqvzfx	91	7	impairment	impairment	NN
cord-021494-9glqvzfx	91	8	to	to	TO
cord-021494-9glqvzfx	91	9	guide	guide	VB
cord-021494-9glqvzfx	91	10	drug	drug	NN
cord-021494-9glqvzfx	91	11	dosage	dosage	NN
cord-021494-9glqvzfx	91	12	demonstrate	demonstrate	VB
cord-021494-9glqvzfx	91	13	the	the	DT
cord-021494-9glqvzfx	91	14	benefit	benefit	NN
cord-021494-9glqvzfx	91	15	of	of	IN
cord-021494-9glqvzfx	91	16	using	use	VBG
cord-021494-9glqvzfx	91	17	patient	patient	JJ
cord-021494-9glqvzfx	91	18	physiology	physiology	NN
cord-021494-9glqvzfx	91	19	to	to	TO
cord-021494-9glqvzfx	91	20	customize	customize	VB
cord-021494-9glqvzfx	91	21	therapy	therapy	NN
cord-021494-9glqvzfx	91	22	.	.	.
cord-021494-9glqvzfx	92	1	It	-PRON-	PRP
cord-021494-9glqvzfx	92	2	is	be	VBZ
cord-021494-9glqvzfx	92	3	likely	likely	JJ
cord-021494-9glqvzfx	92	4	that	that	IN
cord-021494-9glqvzfx	92	5	individual	individual	JJ
cord-021494-9glqvzfx	92	6	differences	difference	NNS
cord-021494-9glqvzfx	92	7	in	in	IN
cord-021494-9glqvzfx	92	8	enzymatic	enzymatic	JJ
cord-021494-9glqvzfx	92	9	metabolism	metabolism	NN
cord-021494-9glqvzfx	92	10	of	of	IN
cord-021494-9glqvzfx	92	11	particular	particular	JJ
cord-021494-9glqvzfx	92	12	drugs	drug	NNS
cord-021494-9glqvzfx	92	13	(	(	-LRB-
cord-021494-9glqvzfx	92	14	for	for	IN
cord-021494-9glqvzfx	92	15	instance	instance	NN
cord-021494-9glqvzfx	92	16	,	,	,
cord-021494-9glqvzfx	92	17	warfarin	warfarin	NN
cord-021494-9glqvzfx	92	18	or	or	CC
cord-021494-9glqvzfx	92	19	tamoxifen	tamoxifen	NN
cord-021494-9glqvzfx	92	20	)	)	-RRB-
cord-021494-9glqvzfx	92	21	will	will	MD
cord-021494-9glqvzfx	92	22	be	be	VB
cord-021494-9glqvzfx	92	23	defined	define	VBN
cord-021494-9glqvzfx	92	24	at	at	IN
cord-021494-9glqvzfx	92	25	the	the	DT
cord-021494-9glqvzfx	92	26	enzyme	enzyme	NN
cord-021494-9glqvzfx	92	27	sequence	sequence	NN
cord-021494-9glqvzfx	92	28	level	level	NN
cord-021494-9glqvzfx	92	29	,	,	,
cord-021494-9glqvzfx	92	30	and	and	CC
cord-021494-9glqvzfx	92	31	that	that	IN
cord-021494-9glqvzfx	92	32	gene	gene	NN
cord-021494-9glqvzfx	92	33	haplotype	haplotype	NN
cord-021494-9glqvzfx	92	34	data	datum	NNS
cord-021494-9glqvzfx	92	35	will	will	MD
cord-021494-9glqvzfx	92	36	be	be	VB
cord-021494-9glqvzfx	92	37	determined	determine	VBN
cord-021494-9glqvzfx	92	38	for	for	IN
cord-021494-9glqvzfx	92	39	new	new	JJ
cord-021494-9glqvzfx	92	40	patients	patient	NNS
cord-021494-9glqvzfx	92	41	prior	prior	RB
cord-021494-9glqvzfx	92	42	to	to	IN
cord-021494-9glqvzfx	92	43	receipt	receipt	NN
cord-021494-9glqvzfx	92	44	of	of	IN
cord-021494-9glqvzfx	92	45	these	these	DT
cord-021494-9glqvzfx	92	46	drugs	drug	NNS
cord-021494-9glqvzfx	92	47	.	.	.
cord-021494-9glqvzfx	93	1	Current	current	JJ
cord-021494-9glqvzfx	93	2	uses	use	NNS
cord-021494-9glqvzfx	93	3	of	of	IN
cord-021494-9glqvzfx	93	4	prostate	prostate	NN
cord-021494-9glqvzfx	93	5	-	-	HYPH
cord-021494-9glqvzfx	93	6	specific	specific	JJ
cord-021494-9glqvzfx	93	7	antigen	antigen	NN
cord-021494-9glqvzfx	93	8	(	(	-LRB-
cord-021494-9glqvzfx	93	9	PSA	PSA	NNP
cord-021494-9glqvzfx	93	10	)	)	-RRB-
cord-021494-9glqvzfx	93	11	to	to	TO
cord-021494-9glqvzfx	93	12	screen	screen	VB
cord-021494-9glqvzfx	93	13	for	for	IN
cord-021494-9glqvzfx	93	14	prostate	prostate	NN
cord-021494-9glqvzfx	93	15	carcinoma	carcinoma	NN
cord-021494-9glqvzfx	93	16	and	and	CC
cord-021494-9glqvzfx	93	17	its	-PRON-	PRP$
cord-021494-9glqvzfx	93	18	recurrence	recurrence	NN
cord-021494-9glqvzfx	93	19	demonstrates	demonstrate	VBZ
cord-021494-9glqvzfx	93	20	the	the	DT
cord-021494-9glqvzfx	93	21	benefit	benefit	NN
cord-021494-9glqvzfx	93	22	of	of	IN
cord-021494-9glqvzfx	93	23	serum	serum	NN
cord-021494-9glqvzfx	93	24	biomarkers	biomarker	NNS
cord-021494-9glqvzfx	93	25	in	in	IN
cord-021494-9glqvzfx	93	26	common	common	JJ
cord-021494-9glqvzfx	93	27	neoplasms	neoplasm	NNS
cord-021494-9glqvzfx	93	28	.	.	.
cord-021494-9glqvzfx	94	1	It	-PRON-	PRP
cord-021494-9glqvzfx	94	2	is	be	VBZ
cord-021494-9glqvzfx	94	3	likely	likely	JJ
cord-021494-9glqvzfx	94	4	that	that	IN
cord-021494-9glqvzfx	94	5	high	high	JJ
cord-021494-9glqvzfx	94	6	-	-	HYPH
cord-021494-9glqvzfx	94	7	sensitivity	sensitivity	NN
cord-021494-9glqvzfx	94	8	screening	screening	NN
cord-021494-9glqvzfx	94	9	of	of	IN
cord-021494-9glqvzfx	94	10	single	single	JJ
cord-021494-9glqvzfx	94	11	and	and	CC
cord-021494-9glqvzfx	94	12	clustered	clustered	JJ
cord-021494-9glqvzfx	94	13	serum	serum	NN
cord-021494-9glqvzfx	94	14	analytes	analyte	NNS
cord-021494-9glqvzfx	94	15	will	will	MD
cord-021494-9glqvzfx	94	16	lead	lead	VB
cord-021494-9glqvzfx	94	17	to	to	IN
cord-021494-9glqvzfx	94	18	improved	improved	JJ
cord-021494-9glqvzfx	94	19	methods	method	NNS
cord-021494-9glqvzfx	94	20	for	for	IN
cord-021494-9glqvzfx	94	21	early	early	JJ
cord-021494-9glqvzfx	94	22	detection	detection	NN
cord-021494-9glqvzfx	94	23	and	and	CC
cord-021494-9glqvzfx	94	24	persistence	persistence	NN
cord-021494-9glqvzfx	94	25	of	of	IN
cord-021494-9glqvzfx	94	26	neoplasms	neoplasm	NNS
cord-021494-9glqvzfx	94	27	,	,	,
cord-021494-9glqvzfx	94	28	autoimmune	autoimmune	JJ
cord-021494-9glqvzfx	94	29	diseases	disease	NNS
cord-021494-9glqvzfx	94	30	,	,	,
cord-021494-9glqvzfx	94	31	and	and	CC
cord-021494-9glqvzfx	94	32	infections	infection	NNS
cord-021494-9glqvzfx	94	33	.	.	.
cord-021494-9glqvzfx	95	1	Pathologists	pathologist	NNS
cord-021494-9glqvzfx	95	2	consider	consider	VBP
cord-021494-9glqvzfx	95	3	each	each	DT
cord-021494-9glqvzfx	95	4	disease	disease	NN
cord-021494-9glqvzfx	95	5	to	to	TO
cord-021494-9glqvzfx	95	6	have	have	VB
cord-021494-9glqvzfx	95	7	a	a	DT
cord-021494-9glqvzfx	95	8	natural	natural	JJ
cord-021494-9glqvzfx	95	9	,	,	,
cord-021494-9glqvzfx	95	10	mechanical	mechanical	JJ
cord-021494-9glqvzfx	95	11	,	,	,
cord-021494-9glqvzfx	95	12	physicochemical	physicochemical	JJ
cord-021494-9glqvzfx	95	13	basis	basis	NN
cord-021494-9glqvzfx	95	14	.	.	.
cord-021494-9glqvzfx	96	1	Each	each	DT
cord-021494-9glqvzfx	96	2	disease	disease	NN
cord-021494-9glqvzfx	96	3	has	have	VBZ
cord-021494-9glqvzfx	96	4	an	an	DT
cord-021494-9glqvzfx	96	5	etiology	etiology	NN
cord-021494-9glqvzfx	96	6	(	(	-LRB-
cord-021494-9glqvzfx	96	7	initial	initial	JJ
cord-021494-9glqvzfx	96	8	cause	cause	NN
cord-021494-9glqvzfx	96	9	)	)	-RRB-
cord-021494-9glqvzfx	96	10	,	,	,
cord-021494-9glqvzfx	96	11	a	a	DT
cord-021494-9glqvzfx	96	12	pathogenesis	pathogenesis	NN
cord-021494-9glqvzfx	96	13	(	(	-LRB-
cord-021494-9glqvzfx	96	14	stepwise	stepwise	JJ
cord-021494-9glqvzfx	96	15	progression	progression	NN
cord-021494-9glqvzfx	96	16	)	)	-RRB-
cord-021494-9glqvzfx	96	17	,	,	,
cord-021494-9glqvzfx	96	18	and	and	CC
cord-021494-9glqvzfx	96	19	a	a	DT
cord-021494-9glqvzfx	96	20	natural	natural	JJ
cord-021494-9glqvzfx	96	21	history	history	NN
cord-021494-9glqvzfx	96	22	with	with	IN
cord-021494-9glqvzfx	96	23	effects	effect	NNS
cord-021494-9glqvzfx	96	24	on	on	IN
cord-021494-9glqvzfx	96	25	normal	normal	JJ
cord-021494-9glqvzfx	96	26	function	function	NN
cord-021494-9glqvzfx	96	27	(	(	-LRB-
cord-021494-9glqvzfx	96	28	clinical	clinical	JJ
cord-021494-9glqvzfx	96	29	outcome	outcome	NN
cord-021494-9glqvzfx	96	30	)	)	-RRB-
cord-021494-9glqvzfx	96	31	.	.	.
cord-021494-9glqvzfx	97	1	Pathologists	pathologist	NNS
cord-021494-9glqvzfx	97	2	collect	collect	VBP
cord-021494-9glqvzfx	97	3	the	the	DT
cord-021494-9glqvzfx	97	4	data	datum	NNS
cord-021494-9glqvzfx	97	5	needed	need	VBN
cord-021494-9glqvzfx	97	6	to	to	TO
cord-021494-9glqvzfx	97	7	answer	answer	VB
cord-021494-9glqvzfx	97	8	patients	patient	NNS
cord-021494-9glqvzfx	97	9	'	'	POS
cord-021494-9glqvzfx	97	10	and	and	CC
cord-021494-9glqvzfx	97	11	clinicians	clinician	NNS
cord-021494-9glqvzfx	97	12	'	'	POS
cord-021494-9glqvzfx	97	13	questions	question	NNS
cord-021494-9glqvzfx	97	14	,	,	,
cord-021494-9glqvzfx	97	15	simply	simply	RB
cord-021494-9glqvzfx	97	16	phrased	phrase	VBN
cord-021494-9glqvzfx	97	17	as	as	IN
cord-021494-9glqvzfx	97	18	"	"	``
cord-021494-9glqvzfx	97	19	what	what	WP
cord-021494-9glqvzfx	97	20	is	be	VBZ
cord-021494-9glqvzfx	97	21	it	-PRON-	PRP
cord-021494-9glqvzfx	97	22	?	?	.
cord-021494-9glqvzfx	97	23	"	"	''
cord-021494-9glqvzfx	98	1	(	(	-LRB-
cord-021494-9glqvzfx	98	2	diagnosis	diagnosis	NN
cord-021494-9glqvzfx	98	3	)	)	-RRB-
cord-021494-9glqvzfx	98	4	,	,	,
cord-021494-9glqvzfx	98	5	"	"	``
cord-021494-9glqvzfx	98	6	how	how	WRB
cord-021494-9glqvzfx	98	7	it	-PRON-	PRP
cord-021494-9glqvzfx	98	8	going	go	VBG
cord-021494-9glqvzfx	98	9	to	to	TO
cord-021494-9glqvzfx	98	10	behave	behave	VB
cord-021494-9glqvzfx	98	11	?	?	.
cord-021494-9glqvzfx	98	12	"	"	''
cord-021494-9glqvzfx	99	1	(	(	-LRB-
cord-021494-9glqvzfx	99	2	prognosis	prognosis	NN
cord-021494-9glqvzfx	99	3	)	)	-RRB-
cord-021494-9glqvzfx	99	4	,	,	,
cord-021494-9glqvzfx	99	5	and	and	CC
cord-021494-9glqvzfx	99	6	"	"	``
cord-021494-9glqvzfx	99	7	how	how	WRB
cord-021494-9glqvzfx	99	8	do	do	VBP
cord-021494-9glqvzfx	99	9	I	-PRON-	PRP
cord-021494-9glqvzfx	99	10	treat	treat	VB
cord-021494-9glqvzfx	99	11	it	-PRON-	PRP
cord-021494-9glqvzfx	99	12	?	?	.
cord-021494-9glqvzfx	99	13	"	"	''
cord-021494-9glqvzfx	100	1	(	(	-LRB-
cord-021494-9glqvzfx	100	2	prediction	prediction	NN
cord-021494-9glqvzfx	100	3	of	of	IN
cord-021494-9glqvzfx	100	4	response	response	NN
cord-021494-9glqvzfx	100	5	to	to	IN
cord-021494-9glqvzfx	100	6	therapy	therapy	NN
cord-021494-9glqvzfx	100	7	)	)	-RRB-
cord-021494-9glqvzfx	100	8	.	.	.
cord-021494-9glqvzfx	101	1	Instincts	instinct	NNS
cord-021494-9glqvzfx	101	2	and	and	CC
cord-021494-9glqvzfx	101	3	diagnostic	diagnostic	JJ
cord-021494-9glqvzfx	101	4	criteria	criterion	NNS
cord-021494-9glqvzfx	101	5	,	,	,
cord-021494-9glqvzfx	101	6	as	as	RB
cord-021494-9glqvzfx	101	7	well	well	RB
cord-021494-9glqvzfx	101	8	as	as	IN
cord-021494-9glqvzfx	101	9	the	the	DT
cord-021494-9glqvzfx	101	10	optical	optical	JJ
cord-021494-9glqvzfx	101	11	,	,	,
cord-021494-9glqvzfx	101	12	mechanical	mechanical	JJ
cord-021494-9glqvzfx	101	13	,	,	,
cord-021494-9glqvzfx	101	14	chemical	chemical	NN
cord-021494-9glqvzfx	101	15	,	,	,
cord-021494-9glqvzfx	101	16	and	and	CC
cord-021494-9glqvzfx	101	17	computing	computing	NN
cord-021494-9glqvzfx	101	18	technologies	technology	NNS
cord-021494-9glqvzfx	101	19	described	describe	VBN
cord-021494-9glqvzfx	101	20	previously	previously	RB
cord-021494-9glqvzfx	101	21	,	,	,
cord-021494-9glqvzfx	101	22	are	be	VBP
cord-021494-9glqvzfx	101	23	the	the	DT
cord-021494-9glqvzfx	101	24	basis	basis	NN
cord-021494-9glqvzfx	101	25	for	for	IN
cord-021494-9glqvzfx	101	26	modern	modern	JJ
cord-021494-9glqvzfx	101	27	service	service	NN
cord-021494-9glqvzfx	101	28	pathology	pathology	NN
cord-021494-9glqvzfx	101	29	.	.	.
cord-021494-9glqvzfx	102	1	As	as	IN
cord-021494-9glqvzfx	102	2	the	the	DT
cord-021494-9glqvzfx	102	3	human	human	JJ
cord-021494-9glqvzfx	102	4	genome	genome	NN
cord-021494-9glqvzfx	102	5	is	be	VBZ
cord-021494-9glqvzfx	102	6	deciphered	decipher	VBN
cord-021494-9glqvzfx	102	7	,	,	,
cord-021494-9glqvzfx	102	8	and	and	CC
cord-021494-9glqvzfx	102	9	as	as	IN
cord-021494-9glqvzfx	102	10	the	the	DT
cord-021494-9glqvzfx	102	11	complex	complex	JJ
cord-021494-9glqvzfx	102	12	interactions	interaction	NNS
cord-021494-9glqvzfx	102	13	of	of	IN
cord-021494-9glqvzfx	102	14	cellular	cellular	JJ
cord-021494-9glqvzfx	102	15	biochemistry	biochemistry	NN
cord-021494-9glqvzfx	102	16	are	be	VBP
cord-021494-9glqvzfx	102	17	refined	refine	VBN
cord-021494-9glqvzfx	102	18	,	,	,
cord-021494-9glqvzfx	102	19	risk	risk	NN
cord-021494-9glqvzfx	102	20	of	of	IN
cord-021494-9glqvzfx	102	21	disease	disease	NN
cord-021494-9glqvzfx	102	22	in	in	IN
cord-021494-9glqvzfx	102	23	unaffected	unaffected	JJ
cord-021494-9glqvzfx	102	24	individuals	individual	NNS
cord-021494-9glqvzfx	102	25	will	will	MD
cord-021494-9glqvzfx	102	26	be	be	VB
cord-021494-9glqvzfx	102	27	calculable	calculable	JJ
cord-021494-9glqvzfx	102	28	,	,	,
cord-021494-9glqvzfx	102	29	disease	disease	NN
cord-021494-9glqvzfx	102	30	diagnosis	diagnosis	NN
cord-021494-9glqvzfx	102	31	will	will	MD
cord-021494-9glqvzfx	102	32	be	be	VB
cord-021494-9glqvzfx	102	33	increasingly	increasingly	RB
cord-021494-9glqvzfx	102	34	accurate	accurate	JJ
cord-021494-9glqvzfx	102	35	and	and	CC
cord-021494-9glqvzfx	102	36	prognostic	prognostic	JJ
cord-021494-9glqvzfx	102	37	,	,	,
cord-021494-9glqvzfx	102	38	and	and	CC
cord-021494-9glqvzfx	102	39	molecular	molecular	JJ
cord-021494-9glqvzfx	102	40	subsets	subset	NNS
cord-021494-9glqvzfx	102	41	of	of	IN
cord-021494-9glqvzfx	102	42	morphologically	morphologically	RB
cord-021494-9glqvzfx	102	43	defined	define	VBN
cord-021494-9glqvzfx	102	44	disease	disease	NN
cord-021494-9glqvzfx	102	45	entities	entity	NNS
cord-021494-9glqvzfx	102	46	will	will	MD
cord-021494-9glqvzfx	102	47	be	be	VB
cord-021494-9glqvzfx	102	48	used	use	VBN
cord-021494-9glqvzfx	102	49	to	to	TO
cord-021494-9glqvzfx	102	50	guide	guide	VB
cord-021494-9glqvzfx	102	51	customized	customize	VBN
cord-021494-9glqvzfx	102	52	therapy	therapy	NN
cord-021494-9glqvzfx	102	53	for	for	IN
cord-021494-9glqvzfx	102	54	individual	individual	JJ
cord-021494-9glqvzfx	102	55	patients	patient	NNS
cord-021494-9glqvzfx	102	56	.	.	.
cord-021494-9glqvzfx	103	1	It	-PRON-	PRP
cord-021494-9glqvzfx	103	2	is	be	VBZ
cord-021494-9glqvzfx	103	3	a	a	DT
cord-021494-9glqvzfx	103	4	great	great	JJ
cord-021494-9glqvzfx	103	5	time	time	NN
cord-021494-9glqvzfx	103	6	in	in	IN
cord-021494-9glqvzfx	103	7	history	history	NN
cord-021494-9glqvzfx	103	8	to	to	TO
cord-021494-9glqvzfx	103	9	be	be	VB
cord-021494-9glqvzfx	103	10	a	a	DT
cord-021494-9glqvzfx	103	11	pathologist	pathologist	NN
cord-021494-9glqvzfx	103	12	.	.	.
cord-021494-9glqvzfx	104	1	n	n	NNP
cord-021494-9glqvzfx	105	1	Clinically	clinically	RB
cord-021494-9glqvzfx	105	2	,	,	,
cord-021494-9glqvzfx	105	3	diseases	disease	NNS
cord-021494-9glqvzfx	105	4	present	present	JJ
cord-021494-9glqvzfx	105	5	to	to	IN
cord-021494-9glqvzfx	105	6	front	front	JJ
cord-021494-9glqvzfx	105	7	-	-	HYPH
cord-021494-9glqvzfx	105	8	line	line	NN
cord-021494-9glqvzfx	105	9	physicians	physician	NNS
cord-021494-9glqvzfx	105	10	as	as	IN
cord-021494-9glqvzfx	105	11	patients	patient	NNS
cord-021494-9glqvzfx	105	12	with	with	IN
cord-021494-9glqvzfx	105	13	sets	set	NNS
cord-021494-9glqvzfx	105	14	of	of	IN
cord-021494-9glqvzfx	105	15	signs	sign	NNS
cord-021494-9glqvzfx	105	16	and	and	CC
cord-021494-9glqvzfx	105	17	symptoms	symptom	NNS
cord-021494-9glqvzfx	105	18	.	.	.
cord-021494-9glqvzfx	106	1	Symptoms	symptom	NNS
cord-021494-9glqvzfx	106	2	are	be	VBP
cord-021494-9glqvzfx	106	3	the	the	DT
cord-021494-9glqvzfx	106	4	patient	patient	NN
cord-021494-9glqvzfx	106	5	's	's	POS
cord-021494-9glqvzfx	106	6	complaints	complaint	NNS
cord-021494-9glqvzfx	106	7	of	of	IN
cord-021494-9glqvzfx	106	8	perceived	perceive	VBN
cord-021494-9glqvzfx	106	9	abnormalities	abnormality	NNS
cord-021494-9glqvzfx	106	10	.	.	.
cord-021494-9glqvzfx	107	1	Signs	sign	NNS
cord-021494-9glqvzfx	107	2	are	be	VBP
cord-021494-9glqvzfx	107	3	detected	detect	VBN
cord-021494-9glqvzfx	107	4	by	by	IN
cord-021494-9glqvzfx	107	5	examination	examination	NN
cord-021494-9glqvzfx	107	6	of	of	IN
cord-021494-9glqvzfx	107	7	the	the	DT
cord-021494-9glqvzfx	107	8	patient	patient	NN
cord-021494-9glqvzfx	107	9	.	.	.
cord-021494-9glqvzfx	108	1	The	the	DT
cord-021494-9glqvzfx	108	2	clinical	clinical	JJ
cord-021494-9glqvzfx	108	3	team	team	NN
cord-021494-9glqvzfx	108	4	(	(	-LRB-
cord-021494-9glqvzfx	108	5	including	include	VBG
cord-021494-9glqvzfx	108	6	the	the	DT
cord-021494-9glqvzfx	108	7	pathologist	pathologist	NN
cord-021494-9glqvzfx	108	8	)	)	-RRB-
cord-021494-9glqvzfx	108	9	evaluate	evaluate	VB
cord-021494-9glqvzfx	108	10	the	the	DT
cord-021494-9glqvzfx	108	11	patient	patient	NN
cord-021494-9glqvzfx	108	12	based	base	VBN
cord-021494-9glqvzfx	108	13	on	on	IN
cord-021494-9glqvzfx	108	14	the	the	DT
cord-021494-9glqvzfx	108	15	possible	possible	JJ
cord-021494-9glqvzfx	108	16	causes	cause	NNS
cord-021494-9glqvzfx	108	17	of	of	IN
cord-021494-9glqvzfx	108	18	the	the	DT
cord-021494-9glqvzfx	108	19	signs	sign	NNS
cord-021494-9glqvzfx	108	20	and	and	CC
cord-021494-9glqvzfx	108	21	symptoms	symptom	NNS
cord-021494-9glqvzfx	108	22	(	(	-LRB-
cord-021494-9glqvzfx	108	23	the	the	DT
cord-021494-9glqvzfx	108	24	differential	differential	JJ
cord-021494-9glqvzfx	108	25	diagnosis	diagnosis	NN
cord-021494-9glqvzfx	108	26	)	)	-RRB-
cord-021494-9glqvzfx	108	27	.	.	.
cord-021494-9glqvzfx	109	1	n	n	NNP
cord-021494-9glqvzfx	110	1	Pathologically	pathologically	RB
cord-021494-9glqvzfx	110	2	,	,	,
cord-021494-9glqvzfx	110	3	disease	disease	NN
cord-021494-9glqvzfx	110	4	is	be	VBZ
cord-021494-9glqvzfx	110	5	diagnosed	diagnose	VBN
cord-021494-9glqvzfx	110	6	by	by	IN
cord-021494-9glqvzfx	110	7	determining	determine	VBG
cord-021494-9glqvzfx	110	8	whether	whether	IN
cord-021494-9glqvzfx	110	9	the	the	DT
cord-021494-9glqvzfx	110	10	morphologic	morphologic	JJ
cord-021494-9glqvzfx	110	11	features	feature	NNS
cord-021494-9glqvzfx	110	12	match	match	VBP
cord-021494-9glqvzfx	110	13	the	the	DT
cord-021494-9glqvzfx	110	14	set	set	NN
cord-021494-9glqvzfx	110	15	of	of	IN
cord-021494-9glqvzfx	110	16	diagnostic	diagnostic	JJ
cord-021494-9glqvzfx	110	17	criteria	criterion	NNS
cord-021494-9glqvzfx	110	18	previously	previously	RB
cord-021494-9glqvzfx	110	19	described	describe	VBN
cord-021494-9glqvzfx	110	20	for	for	IN
cord-021494-9glqvzfx	110	21	each	each	DT
cord-021494-9glqvzfx	110	22	disease	disease	NN
cord-021494-9glqvzfx	110	23	.	.	.
cord-021494-9glqvzfx	111	1	Pathologists	pathologist	NNS
cord-021494-9glqvzfx	111	2	diagnose	diagnose	VBP
cord-021494-9glqvzfx	111	3	disease	disease	NN
cord-021494-9glqvzfx	111	4	by	by	IN
cord-021494-9glqvzfx	111	5	generating	generate	VBG
cord-021494-9glqvzfx	111	6	a	a	DT
cord-021494-9glqvzfx	111	7	differential	differential	JJ
cord-021494-9glqvzfx	111	8	diagnosis	diagnosis	NN
cord-021494-9glqvzfx	111	9	,	,	,
cord-021494-9glqvzfx	111	10	then	then	RB
cord-021494-9glqvzfx	111	11	finding	find	VBG
cord-021494-9glqvzfx	111	12	the	the	DT
cord-021494-9glqvzfx	111	13	best	good	JJS
cord-021494-9glqvzfx	111	14	fit	fit	NN
cord-021494-9glqvzfx	111	15	for	for	IN
cord-021494-9glqvzfx	111	16	the	the	DT
cord-021494-9glqvzfx	111	17	clinical	clinical	JJ
cord-021494-9glqvzfx	111	18	presentation	presentation	NN
cord-021494-9glqvzfx	111	19	,	,	,
cord-021494-9glqvzfx	111	20	the	the	DT
cord-021494-9glqvzfx	111	21	radiographic	radiographic	JJ
cord-021494-9glqvzfx	111	22	appearance	appearance	NN
cord-021494-9glqvzfx	111	23	,	,	,
cord-021494-9glqvzfx	111	24	and	and	CC
cord-021494-9glqvzfx	111	25	the	the	DT
cord-021494-9glqvzfx	111	26	pathologic	pathologic	JJ
cord-021494-9glqvzfx	111	27	(	(	-LRB-
cord-021494-9glqvzfx	111	28	both	both	DT
cord-021494-9glqvzfx	111	29	clinical	clinical	JJ
cord-021494-9glqvzfx	111	30	lab	lab	NN
cord-021494-9glqvzfx	111	31	and	and	CC
cord-021494-9glqvzfx	111	32	morphologic	morphologic	JJ
cord-021494-9glqvzfx	111	33	)	)	-RRB-
cord-021494-9glqvzfx	111	34	findings	finding	NNS
cord-021494-9glqvzfx	111	35	.	.	.
cord-021494-9glqvzfx	112	1	n	n	NNP
cord-021494-9glqvzfx	112	2	Etiology	Etiology	NNP
cord-021494-9glqvzfx	112	3	describes	describe	VBZ
cord-021494-9glqvzfx	112	4	the	the	DT
cord-021494-9glqvzfx	112	5	causes	cause	NNS
cord-021494-9glqvzfx	112	6	of	of	IN
cord-021494-9glqvzfx	112	7	a	a	DT
cord-021494-9glqvzfx	112	8	disease	disease	NN
cord-021494-9glqvzfx	112	9	.	.	.
cord-021494-9glqvzfx	113	1	One	one	CD
cord-021494-9glqvzfx	113	2	disease	disease	NN
cord-021494-9glqvzfx	113	3	entity	entity	NN
cord-021494-9glqvzfx	113	4	can	can	MD
cord-021494-9glqvzfx	113	5	have	have	VB
cord-021494-9glqvzfx	113	6	more	more	JJR
cord-021494-9glqvzfx	113	7	than	than	IN
cord-021494-9glqvzfx	113	8	one	one	CD
cord-021494-9glqvzfx	113	9	etiology	etiology	NN
cord-021494-9glqvzfx	113	10	,	,	,
cord-021494-9glqvzfx	113	11	and	and	CC
cord-021494-9glqvzfx	113	12	a	a	DT
cord-021494-9glqvzfx	113	13	single	single	JJ
cord-021494-9glqvzfx	113	14	etiology	etiology	NN
cord-021494-9glqvzfx	113	15	can	can	MD
cord-021494-9glqvzfx	113	16	lead	lead	VB
cord-021494-9glqvzfx	113	17	to	to	IN
cord-021494-9glqvzfx	113	18	more	more	JJR
cord-021494-9glqvzfx	113	19	than	than	IN
cord-021494-9glqvzfx	113	20	one	one	CD
cord-021494-9glqvzfx	113	21	disease	disease	NN
cord-021494-9glqvzfx	113	22	.	.	.
cord-021494-9glqvzfx	114	1	For	for	IN
cord-021494-9glqvzfx	114	2	example	example	NN
cord-021494-9glqvzfx	114	3	,	,	,
cord-021494-9glqvzfx	114	4	emphysema	emphysema	NN
cord-021494-9glqvzfx	114	5	,	,	,
cord-021494-9glqvzfx	114	6	chronic	chronic	JJ
cord-021494-9glqvzfx	114	7	bronchitis	bronchitis	NN
cord-021494-9glqvzfx	114	8	,	,	,
cord-021494-9glqvzfx	114	9	and	and	CC
cord-021494-9glqvzfx	114	10	small	small	JJ
cord-021494-9glqvzfx	114	11	cell	cell	NN
cord-021494-9glqvzfx	114	12	lung	lung	NN
cord-021494-9glqvzfx	114	13	carcinoma	carcinoma	NN
cord-021494-9glqvzfx	114	14	can	can	MD
cord-021494-9glqvzfx	114	15	all	all	DT
cord-021494-9glqvzfx	114	16	occur	occur	VB
cord-021494-9glqvzfx	114	17	in	in	IN
cord-021494-9glqvzfx	114	18	longterm	longterm	JJ
cord-021494-9glqvzfx	114	19	smokers	smoker	NNS
cord-021494-9glqvzfx	114	20	(	(	-LRB-
cord-021494-9glqvzfx	114	21	different	different	JJ
cord-021494-9glqvzfx	114	22	diseases	disease	NNS
cord-021494-9glqvzfx	114	23	derived	derive	VBN
cord-021494-9glqvzfx	114	24	from	from	IN
cord-021494-9glqvzfx	114	25	a	a	DT
cord-021494-9glqvzfx	114	26	single	single	JJ
cord-021494-9glqvzfx	114	27	etiology	etiology	NN
cord-021494-9glqvzfx	114	28	)	)	-RRB-
cord-021494-9glqvzfx	114	29	.	.	.
cord-021494-9glqvzfx	115	1	Likewise	likewise	RB
cord-021494-9glqvzfx	115	2	,	,	,
cord-021494-9glqvzfx	115	3	the	the	DT
cord-021494-9glqvzfx	115	4	same	same	JJ
cord-021494-9glqvzfx	115	5	disease	disease	NN
cord-021494-9glqvzfx	115	6	(	(	-LRB-
cord-021494-9glqvzfx	115	7	for	for	IN
cord-021494-9glqvzfx	115	8	instance	instance	NN
cord-021494-9glqvzfx	115	9	,	,	,
cord-021494-9glqvzfx	115	10	emphysema	emphysema	NN
cord-021494-9glqvzfx	115	11	of	of	IN
cord-021494-9glqvzfx	115	12	the	the	DT
cord-021494-9glqvzfx	115	13	lung	lung	NN
cord-021494-9glqvzfx	115	14	)	)	-RRB-
cord-021494-9glqvzfx	115	15	can	can	MD
cord-021494-9glqvzfx	115	16	derive	derive	VB
cord-021494-9glqvzfx	115	17	from	from	IN
cord-021494-9glqvzfx	115	18	different	different	JJ
cord-021494-9glqvzfx	115	19	etiologies	etiology	NNS
cord-021494-9glqvzfx	115	20	(	(	-LRB-
cord-021494-9glqvzfx	115	21	emphysema	emphysema	NN
cord-021494-9glqvzfx	115	22	from	from	IN
cord-021494-9glqvzfx	115	23	a-1-antitrypsin	a-1-antitrypsin	PRP$
cord-021494-9glqvzfx	115	24	deficiency	deficiency	NN
cord-021494-9glqvzfx	115	25	or	or	CC
cord-021494-9glqvzfx	115	26	cigarette	cigarette	NN
cord-021494-9glqvzfx	115	27	smoke	smoke	NN
cord-021494-9glqvzfx	115	28	)	)	-RRB-
cord-021494-9glqvzfx	115	29	.	.	.
cord-021494-9glqvzfx	116	1	n	n	NNP
cord-021494-9glqvzfx	117	1	The	the	DT
cord-021494-9glqvzfx	117	2	pathogenesis	pathogenesis	NN
cord-021494-9glqvzfx	117	3	of	of	IN
cord-021494-9glqvzfx	117	4	a	a	DT
cord-021494-9glqvzfx	117	5	disease	disease	NN
cord-021494-9glqvzfx	117	6	describes	describe	VBZ
cord-021494-9glqvzfx	117	7	its	-PRON-	PRP$
cord-021494-9glqvzfx	117	8	stepwise	stepwise	JJ
cord-021494-9glqvzfx	117	9	progression	progression	NN
cord-021494-9glqvzfx	117	10	after	after	IN
cord-021494-9glqvzfx	117	11	initiation	initiation	NN
cord-021494-9glqvzfx	117	12	in	in	IN
cord-021494-9glqvzfx	117	13	response	response	NN
cord-021494-9glqvzfx	117	14	to	to	IN
cord-021494-9glqvzfx	117	15	a	a	DT
cord-021494-9glqvzfx	117	16	specific	specific	JJ
cord-021494-9glqvzfx	117	17	etiologic	etiologic	JJ
cord-021494-9glqvzfx	117	18	factor	factor	NN
cord-021494-9glqvzfx	117	19	(	(	-LRB-
cord-021494-9glqvzfx	117	20	or	or	CC
cord-021494-9glqvzfx	117	21	factors	factor	NNS
cord-021494-9glqvzfx	117	22	)	)	-RRB-
cord-021494-9glqvzfx	117	23	.	.	.
cord-021494-9glqvzfx	118	1	Pathogenesis	Pathogenesis	NNP
cord-021494-9glqvzfx	118	2	can	can	MD
cord-021494-9glqvzfx	118	3	refer	refer	VB
cord-021494-9glqvzfx	118	4	to	to	IN
cord-021494-9glqvzfx	118	5	the	the	DT
cord-021494-9glqvzfx	118	6	changes	change	NNS
cord-021494-9glqvzfx	118	7	in	in	IN
cord-021494-9glqvzfx	118	8	the	the	DT
cord-021494-9glqvzfx	118	9	structure	structure	NN
cord-021494-9glqvzfx	118	10	or	or	CC
cord-021494-9glqvzfx	118	11	function	function	NN
cord-021494-9glqvzfx	118	12	of	of	IN
cord-021494-9glqvzfx	118	13	an	an	DT
cord-021494-9glqvzfx	118	14	organism	organism	NN
cord-021494-9glqvzfx	118	15	at	at	IN
cord-021494-9glqvzfx	118	16	the	the	DT
cord-021494-9glqvzfx	118	17	gross	gross	JJ
cord-021494-9glqvzfx	118	18	/	/	SYM
cord-021494-9glqvzfx	118	19	clinical	clinical	JJ
cord-021494-9glqvzfx	118	20	level	level	NN
cord-021494-9glqvzfx	118	21	,	,	,
cord-021494-9glqvzfx	118	22	and	and	CC
cord-021494-9glqvzfx	118	23	it	-PRON-	PRP
cord-021494-9glqvzfx	118	24	can	can	MD
cord-021494-9glqvzfx	118	25	refer	refer	VB
cord-021494-9glqvzfx	118	26	to	to	IN
cord-021494-9glqvzfx	118	27	the	the	DT
cord-021494-9glqvzfx	118	28	stepwise	stepwise	JJ
cord-021494-9glqvzfx	118	29	molecular	molecular	JJ
cord-021494-9glqvzfx	118	30	abnormalities	abnormality	NNS
cord-021494-9glqvzfx	118	31	leading	lead	VBG
cord-021494-9glqvzfx	118	32	to	to	IN
cord-021494-9glqvzfx	118	33	changes	change	NNS
cord-021494-9glqvzfx	118	34	in	in	IN
cord-021494-9glqvzfx	118	35	cellular	cellular	JJ
cord-021494-9glqvzfx	118	36	and	and	CC
cord-021494-9glqvzfx	118	37	tissue	tissue	NN
cord-021494-9glqvzfx	118	38	function	function	NN
cord-021494-9glqvzfx	118	39	.	.	.
cord-021494-9glqvzfx	119	1	n	n	LS
cord-021494-9glqvzfx	119	2	The	the	DT
cord-021494-9glqvzfx	119	3	natural	natural	JJ
cord-021494-9glqvzfx	119	4	history	history	NN
cord-021494-9glqvzfx	119	5	of	of	IN
cord-021494-9glqvzfx	119	6	a	a	DT
cord-021494-9glqvzfx	119	7	disease	disease	NN
cord-021494-9glqvzfx	119	8	describes	describe	VBZ
cord-021494-9glqvzfx	119	9	the	the	DT
cord-021494-9glqvzfx	119	10	expected	expect	VBN
cord-021494-9glqvzfx	119	11	course	course	NN
cord-021494-9glqvzfx	119	12	of	of	IN
cord-021494-9glqvzfx	119	13	disease	disease	NN
cord-021494-9glqvzfx	119	14	,	,	,
cord-021494-9glqvzfx	119	15	including	include	VBG
cord-021494-9glqvzfx	119	16	chronicity	chronicity	NN
cord-021494-9glqvzfx	119	17	,	,	,
cord-021494-9glqvzfx	119	18	functional	functional	JJ
cord-021494-9glqvzfx	119	19	impairment	impairment	NN
cord-021494-9glqvzfx	119	20	,	,	,
cord-021494-9glqvzfx	119	21	and	and	CC
cord-021494-9glqvzfx	119	22	survival	survival	NN
cord-021494-9glqvzfx	119	23	.	.	.
cord-021494-9glqvzfx	120	1	However	however	RB
cord-021494-9glqvzfx	120	2	,	,	,
cord-021494-9glqvzfx	120	3	not	not	RB
cord-021494-9glqvzfx	120	4	all	all	DT
cord-021494-9glqvzfx	120	5	patients	patient	NNS
cord-021494-9glqvzfx	120	6	with	with	IN
cord-021494-9glqvzfx	120	7	a	a	DT
cord-021494-9glqvzfx	120	8	given	give	VBN
cord-021494-9glqvzfx	120	9	disease	disease	NN
cord-021494-9glqvzfx	120	10	will	will	MD
cord-021494-9glqvzfx	120	11	naturally	naturally	RB
cord-021494-9glqvzfx	120	12	follow	follow	VB
cord-021494-9glqvzfx	120	13	the	the	DT
cord-021494-9glqvzfx	120	14	same	same	JJ
cord-021494-9glqvzfx	120	15	disease	disease	NN
cord-021494-9glqvzfx	120	16	course	course	NN
cord-021494-9glqvzfx	120	17	,	,	,
cord-021494-9glqvzfx	120	18	so	so	CC
cord-021494-9glqvzfx	120	19	differences	difference	NNS
cord-021494-9glqvzfx	120	20	in	in	IN
cord-021494-9glqvzfx	120	21	patient	patient	JJ
cord-021494-9glqvzfx	120	22	outcome	outcome	NN
cord-021494-9glqvzfx	120	23	do	do	VBP
cord-021494-9glqvzfx	120	24	not	not	RB
cord-021494-9glqvzfx	120	25	necessarily	necessarily	RB
cord-021494-9glqvzfx	120	26	correspond	correspond	VB
cord-021494-9glqvzfx	120	27	to	to	IN
cord-021494-9glqvzfx	120	28	incorrect	incorrect	JJ
cord-021494-9glqvzfx	120	29	diagnosis	diagnosis	NN
cord-021494-9glqvzfx	120	30	.	.	.
cord-021494-9glqvzfx	121	1	Variables	variable	NNS
cord-021494-9glqvzfx	121	2	that	that	WDT
cord-021494-9glqvzfx	121	3	independently	independently	RB
cord-021494-9glqvzfx	121	4	correlate	correlate	VBP
cord-021494-9glqvzfx	121	5	with	with	IN
cord-021494-9glqvzfx	121	6	clinical	clinical	JJ
cord-021494-9glqvzfx	121	7	outcome	outcome	NN
cord-021494-9glqvzfx	121	8	differences	difference	NNS
cord-021494-9glqvzfx	121	9	are	be	VBP
cord-021494-9glqvzfx	121	10	called	call	VBN
cord-021494-9glqvzfx	121	11	independent	independent	JJ
cord-021494-9glqvzfx	121	12	prognostic	prognostic	JJ
cord-021494-9glqvzfx	121	13	variables	variable	NNS
cord-021494-9glqvzfx	121	14	,	,	,
cord-021494-9glqvzfx	121	15	and	and	CC
cord-021494-9glqvzfx	121	16	are	be	VBP
cord-021494-9glqvzfx	121	17	assessed	assess	VBN
cord-021494-9glqvzfx	121	18	routinely	routinely	RB
cord-021494-9glqvzfx	121	19	in	in	IN
cord-021494-9glqvzfx	121	20	an	an	DT
cord-021494-9glqvzfx	121	21	effort	effort	NN
cord-021494-9glqvzfx	121	22	to	to	TO
cord-021494-9glqvzfx	121	23	predict	predict	VB
cord-021494-9glqvzfx	121	24	the	the	DT
cord-021494-9glqvzfx	121	25	natural	natural	JJ
cord-021494-9glqvzfx	121	26	history	history	NN
cord-021494-9glqvzfx	121	27	of	of	IN
cord-021494-9glqvzfx	121	28	the	the	DT
cord-021494-9glqvzfx	121	29	disease	disease	NN
cord-021494-9glqvzfx	121	30	in	in	IN
cord-021494-9glqvzfx	121	31	the	the	DT
cord-021494-9glqvzfx	121	32	patient	patient	NN
cord-021494-9glqvzfx	121	33	.	.	.
cord-021494-9glqvzfx	122	1	n	n	LS
cord-021494-9glqvzfx	122	2	Likewise	likewise	RB
cord-021494-9glqvzfx	122	3	,	,	,
cord-021494-9glqvzfx	122	4	variables	variable	NNS
cord-021494-9glqvzfx	122	5	that	that	WDT
cord-021494-9glqvzfx	122	6	independently	independently	RB
cord-021494-9glqvzfx	122	7	correlate	correlate	VBP
cord-021494-9glqvzfx	122	8	with	with	IN
cord-021494-9glqvzfx	122	9	response	response	NN
cord-021494-9glqvzfx	122	10	to	to	IN
cord-021494-9glqvzfx	122	11	therapy	therapy	NN
cord-021494-9glqvzfx	122	12	are	be	VBP
cord-021494-9glqvzfx	122	13	called	call	VBN
cord-021494-9glqvzfx	122	14	independent	independent	JJ
cord-021494-9glqvzfx	122	15	predictive	predictive	JJ
cord-021494-9glqvzfx	122	16	variables	variable	NNS
cord-021494-9glqvzfx	122	17	,	,	,
cord-021494-9glqvzfx	122	18	and	and	CC
cord-021494-9glqvzfx	122	19	are	be	VBP
cord-021494-9glqvzfx	122	20	assessed	assess	VBN
cord-021494-9glqvzfx	122	21	routinely	routinely	RB
cord-021494-9glqvzfx	122	22	in	in	IN
cord-021494-9glqvzfx	122	23	an	an	DT
cord-021494-9glqvzfx	122	24	effort	effort	NN
cord-021494-9glqvzfx	122	25	to	to	TO
cord-021494-9glqvzfx	122	26	optimize	optimize	VB
cord-021494-9glqvzfx	122	27	therapeutic	therapeutic	JJ
cord-021494-9glqvzfx	122	28	response	response	NN
cord-021494-9glqvzfx	122	29	for	for	IN
cord-021494-9glqvzfx	122	30	each	each	DT
cord-021494-9glqvzfx	122	31	patient	patient	NN
cord-021494-9glqvzfx	122	32	.	.	.
cord-021494-9glqvzfx	123	1	Localization	localization	NN
cord-021494-9glqvzfx	123	2	of	of	IN
cord-021494-9glqvzfx	123	3	antigen	antigen	NN
cord-021494-9glqvzfx	123	4	in	in	IN
cord-021494-9glqvzfx	123	5	tissue	tissue	NN
cord-021494-9glqvzfx	123	6	cells	cell	NNS
cord-021494-9glqvzfx	123	7	;	;	:
cord-021494-9glqvzfx	123	8	improvements	improvement	NNS
cord-021494-9glqvzfx	123	9	in	in	IN
cord-021494-9glqvzfx	123	10	a	a	DT
cord-021494-9glqvzfx	123	11	method	method	NN
cord-021494-9glqvzfx	123	12	for	for	IN
cord-021494-9glqvzfx	123	13	the	the	DT
cord-021494-9glqvzfx	123	14	detection	detection	NN
cord-021494-9glqvzfx	123	15	of	of	IN
cord-021494-9glqvzfx	123	16	antigen	antigen	NN
cord-021494-9glqvzfx	123	17	by	by	IN
cord-021494-9glqvzfx	123	18	means	mean	NNS
cord-021494-9glqvzfx	123	19	of	of	IN
cord-021494-9glqvzfx	123	20	fluorescent	fluorescent	JJ
cord-021494-9glqvzfx	123	21	antibody	antibody	NN
cord-021494-9glqvzfx	123	22	General	general	JJ
cord-021494-9glqvzfx	123	23	nature	nature	NN
cord-021494-9glqvzfx	123	24	of	of	IN
cord-021494-9glqvzfx	123	25	the	the	DT
cord-021494-9glqvzfx	123	26	genetic	genetic	JJ
cord-021494-9glqvzfx	123	27	code	code	NN
cord-021494-9glqvzfx	123	28	for	for	IN
cord-021494-9glqvzfx	123	29	proteins	protein	NNS
cord-021494-9glqvzfx	124	1	An	an	DT
cord-021494-9glqvzfx	124	2	immunoglobulin	immunoglobulin	NN
cord-021494-9glqvzfx	124	3	heavy	heavy	JJ
cord-021494-9glqvzfx	124	4	chain	chain	NN
cord-021494-9glqvzfx	124	5	variable	variable	JJ
cord-021494-9glqvzfx	124	6	region	region	NN
cord-021494-9glqvzfx	124	7	gene	gene	NN
cord-021494-9glqvzfx	124	8	is	be	VBZ
cord-021494-9glqvzfx	124	9	generated	generate	VBN
cord-021494-9glqvzfx	124	10	from	from	IN
cord-021494-9glqvzfx	124	11	three	three	CD
cord-021494-9glqvzfx	124	12	segments	segment	NNS
cord-021494-9glqvzfx	124	13	of	of	IN
cord-021494-9glqvzfx	124	14	DNA	dna	NN
cord-021494-9glqvzfx	124	15	:	:	:
cord-021494-9glqvzfx	124	16	VH	VH	NNP
cord-021494-9glqvzfx	124	17	,	,	,
cord-021494-9glqvzfx	124	18	D	D	NNP
cord-021494-9glqvzfx	124	19	and	and	CC
cord-021494-9glqvzfx	124	20	JH	JH	NNP
cord-021494-9glqvzfx	125	1	In	in	IN
cord-021494-9glqvzfx	125	2	search	search	NN
cord-021494-9glqvzfx	125	3	of	of	IN
cord-021494-9glqvzfx	125	4	the	the	DT
cord-021494-9glqvzfx	125	5	origins	origin	NNS
cord-021494-9glqvzfx	125	6	of	of	IN
cord-021494-9glqvzfx	125	7	modern	modern	JJ
cord-021494-9glqvzfx	125	8	surgical	surgical	JJ
cord-021494-9glqvzfx	125	9	pathology	pathology	NN
cord-021494-9glqvzfx	125	10	Formation	formation	NN
cord-021494-9glqvzfx	125	11	and	and	CC
cord-021494-9glqvzfx	125	12	detection	detection	NN
cord-021494-9glqvzfx	125	13	of	of	IN
cord-021494-9glqvzfx	125	14	RNA	RNA	NNP
cord-021494-9glqvzfx	125	15	-	-	HYPH
cord-021494-9glqvzfx	125	16	DNA	dna	NN
cord-021494-9glqvzfx	125	17	hybrid	hybrid	NN
cord-021494-9glqvzfx	125	18	molecules	molecule	NNS
cord-021494-9glqvzfx	125	19	in	in	IN
cord-021494-9glqvzfx	125	20	cytological	cytological	JJ
cord-021494-9glqvzfx	125	21	preparations	preparation	NNS
cord-021494-9glqvzfx	125	22	Expression	Expression	NNP
cord-021494-9glqvzfx	125	23	in	in	IN
cord-021494-9glqvzfx	125	24	Escherichia	Escherichia	NNP
cord-021494-9glqvzfx	125	25	coli	coli	NNS
cord-021494-9glqvzfx	125	26	of	of	IN
cord-021494-9glqvzfx	125	27	chemically	chemically	RB
cord-021494-9glqvzfx	125	28	synthesized	synthesize	VBN
cord-021494-9glqvzfx	125	29	genes	gene	NNS
cord-021494-9glqvzfx	125	30	for	for	IN
cord-021494-9glqvzfx	125	31	human	human	JJ
cord-021494-9glqvzfx	125	32	insulin	insulin	NN
cord-021494-9glqvzfx	125	33	Contagiousness	Contagiousness	NNP
cord-021494-9glqvzfx	125	34	of	of	IN
cord-021494-9glqvzfx	125	35	puerperal	puerperal	JJ
cord-021494-9glqvzfx	125	36	fever	fever	NN
cord-021494-9glqvzfx	125	37	Berliner	Berliner	NNP
cord-021494-9glqvzfx	125	38	Klinische	Klinische	NNP
cord-021494-9glqvzfx	125	39	Wochenschrift	Wochenschrift	NNP
cord-021494-9glqvzfx	125	40	Continuous	continuous	JJ
cord-021494-9glqvzfx	125	41	cultures	culture	NNS
cord-021494-9glqvzfx	125	42	of	of	IN
cord-021494-9glqvzfx	125	43	fused	fuse	VBN
cord-021494-9glqvzfx	125	44	cells	cell	NNS
cord-021494-9glqvzfx	125	45	secreting	secrete	VBG
cord-021494-9glqvzfx	125	46	antibody	antibody	NN
cord-021494-9glqvzfx	125	47	of	of	IN
cord-021494-9glqvzfx	125	48	predefined	predefined	JJ
cord-021494-9glqvzfx	125	49	specificity	specificity	NN
cord-021494-9glqvzfx	125	50	Initial	initial	JJ
cord-021494-9glqvzfx	125	51	sequencing	sequencing	NN
cord-021494-9glqvzfx	125	52	and	and	CC
cord-021494-9glqvzfx	125	53	analysis	analysis	NN
cord-021494-9glqvzfx	125	54	of	of	IN
cord-021494-9glqvzfx	125	55	the	the	DT
cord-021494-9glqvzfx	125	56	human	human	JJ
cord-021494-9glqvzfx	125	57	genome	genome	NN
cord-021494-9glqvzfx	126	1	The	the	DT
cord-021494-9glqvzfx	126	2	immunology	immunology	NN
cord-021494-9glqvzfx	126	3	of	of	IN
cord-021494-9glqvzfx	126	4	transplantation	transplantation	NN
cord-021494-9glqvzfx	126	5	Specific	specific	JJ
cord-021494-9glqvzfx	126	6	enzymatic	enzymatic	JJ
cord-021494-9glqvzfx	126	7	amplification	amplification	NN
cord-021494-9glqvzfx	126	8	of	of	IN
cord-021494-9glqvzfx	126	9	DNA	dna	NN
cord-021494-9glqvzfx	126	10	in	in	IN
cord-021494-9glqvzfx	126	11	vitro	vitro	FW
cord-021494-9glqvzfx	126	12	:	:	:
cord-021494-9glqvzfx	126	13	the	the	DT
cord-021494-9glqvzfx	126	14	polymerase	polymerase	NN
cord-021494-9glqvzfx	126	15	chain	chain	NN
cord-021494-9glqvzfx	126	16	reaction	reaction	NN
cord-021494-9glqvzfx	126	17	The	the	DT
cord-021494-9glqvzfx	126	18	RNA	RNA	NNP
cord-021494-9glqvzfx	126	19	code	code	NN
cord-021494-9glqvzfx	126	20	and	and	CC
cord-021494-9glqvzfx	126	21	protein	protein	NN
cord-021494-9glqvzfx	126	22	synthesis	synthesis	NN
cord-021494-9glqvzfx	126	23	Ignac	Ignac	NNP
cord-021494-9glqvzfx	126	24	Semmelweis	Semmelweis	NNP
cord-021494-9glqvzfx	126	25	and	and	CC
cord-021494-9glqvzfx	126	26	the	the	DT
cord-021494-9glqvzfx	126	27	etiology	etiology	NN
cord-021494-9glqvzfx	126	28	of	of	IN
cord-021494-9glqvzfx	126	29	fetal	fetal	JJ
cord-021494-9glqvzfx	126	30	and	and	CC
cord-021494-9glqvzfx	126	31	neonatal	neonatal	JJ
cord-021494-9glqvzfx	126	32	sepsis	sepsis	NN
cord-021494-9glqvzfx	126	33	Product	product	NN
cord-021494-9glqvzfx	126	34	differentiation	differentiation	NN
cord-021494-9glqvzfx	126	35	by	by	IN
cord-021494-9glqvzfx	126	36	analysis	analysis	NN
cord-021494-9glqvzfx	126	37	of	of	IN
cord-021494-9glqvzfx	126	38	DNA	dna	NN
cord-021494-9glqvzfx	126	39	melting	melting	NN
cord-021494-9glqvzfx	126	40	curves	curve	NNS
cord-021494-9glqvzfx	126	41	during	during	IN
cord-021494-9glqvzfx	126	42	the	the	DT
cord-021494-9glqvzfx	126	43	polymerase	polymerase	NN
cord-021494-9glqvzfx	126	44	chain	chain	NN
cord-021494-9glqvzfx	126	45	reaction	reaction	NN
cord-021494-9glqvzfx	127	1	The	the	DT
cord-021494-9glqvzfx	127	2	continuing	continue	VBG
cord-021494-9glqvzfx	127	3	role	role	NN
cord-021494-9glqvzfx	127	4	of	of	IN
cord-021494-9glqvzfx	127	5	morphology	morphology	NN
cord-021494-9glqvzfx	127	6	in	in	IN
cord-021494-9glqvzfx	127	7	the	the	DT
cord-021494-9glqvzfx	127	8	molecular	molecular	JJ
cord-021494-9glqvzfx	127	9	age	age	NN
cord-021494-9glqvzfx	127	10	DNA	dna	NN
cord-021494-9glqvzfx	127	11	sequencing	sequencing	NN
cord-021494-9glqvzfx	127	12	with	with	IN
cord-021494-9glqvzfx	127	13	chainterminating	chainterminate	VBG
cord-021494-9glqvzfx	127	14	inhibitors	inhibitor	NNS
cord-021494-9glqvzfx	127	15	Fluorescence	Fluorescence	NNP
cord-021494-9glqvzfx	127	16	detection	detection	NN
cord-021494-9glqvzfx	127	17	in	in	IN
cord-021494-9glqvzfx	127	18	automated	automate	VBN
cord-021494-9glqvzfx	127	19	DNA	dna	NN
cord-021494-9glqvzfx	127	20	sequence	sequence	NN
cord-021494-9glqvzfx	127	21	analysis	analysis	NN
cord-021494-9glqvzfx	127	22	Rudolf	Rudolf	NNP
cord-021494-9glqvzfx	127	23	Virchow	Virchow	NNP
cord-021494-9glqvzfx	127	24	-	-	HYPH
cord-021494-9glqvzfx	127	25	father	father	NN
cord-021494-9glqvzfx	127	26	of	of	IN
cord-021494-9glqvzfx	127	27	cellular	cellular	JJ
cord-021494-9glqvzfx	127	28	pathology	pathology	NN
cord-021494-9glqvzfx	128	1	The	the	DT
cord-021494-9glqvzfx	128	2	sequence	sequence	NN
cord-021494-9glqvzfx	128	3	of	of	IN
cord-021494-9glqvzfx	128	4	the	the	DT
cord-021494-9glqvzfx	128	5	human	human	JJ
cord-021494-9glqvzfx	128	6	genome	genome	NN
cord-021494-9glqvzfx	128	7	Molecular	Molecular	NNP
cord-021494-9glqvzfx	128	8	structure	structure	NN
cord-021494-9glqvzfx	128	9	of	of	IN
cord-021494-9glqvzfx	128	10	nucleic	nucleic	JJ
cord-021494-9glqvzfx	128	11	acids	acid	NNS
cord-021494-9glqvzfx	128	12	;	;	:
cord-021494-9glqvzfx	128	13	a	a	DT
cord-021494-9glqvzfx	128	14	structure	structure	NN
cord-021494-9glqvzfx	128	15	for	for	IN
cord-021494-9glqvzfx	128	16	deoxyribose	deoxyribose	JJ
cord-021494-9glqvzfx	128	17	nucleic	nucleic	JJ
cord-021494-9glqvzfx	128	18	acid	acid	NN