id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-337740-8ujk830g	Matencio, Adrián	Cyclic Oligosaccharides as Active Drugs, an Updated Review	2020-09-29		.txt	text/plain	8089	385	39	There have been many reviews of the cyclic oligosaccharide cyclodextrin (CD) and CD-based materials used for drug delivery, but the capacity of CDs to complex different agents and their own intrinsic properties suggest they might also be considered for use as active drugs, not only as carriers. The review is divided into lipid-related diseases, aggregation diseases, antiviral and antiparasitic activities, anti-anesthetic agent, function in diet, removal of organic toxins, CDs and collagen, cell differentiation, and finally, their use in contact lenses in which no drug other than CDs are involved. In addition to CDs, another dietary indigestible cyclic oligosaccharide formed by four D-glucopyranosyl residues linked by alternating α(1→3) and α(1→6) glucosidic linkages was recently found to have intrinsic bioactivity cyclic nigerosyl-1,6-nigerose or cyclotetraglucose (CNN, Figure 1 [21] ) The present review will update the most relevant applications mentioned in the review made by Braga et al., 2019 , including applications, such as the ability of CDs to combat aggregation diseases, their dietary functions, toxins removal, cell differentiation, and their application in contact lenses.	./cache/cord-337740-8ujk830g.txt	./txt/cord-337740-8ujk830g.txt