id author title date pages extension mime words sentences flesch summary cache txt cord-342204-9tgxijvn Nuzzo, Domenico Potential neurological effects of severe COVID-19 infection 2020-07-03 .txt text/plain 3227 183 44 In this axis, virus-induced inflammation and oxidative stress could be the common mechanisms responsible for CoV neurological symptoms. People with COVID-19 generally develop respiratory symptoms but the increasing evidence shows that some patients with a severe infection also develop neurological ailments like confusion, stroke, seizure, or loss of smell and taste. Recent studies discussed the neuroinvasive potential of SARS-CoV-2; in fact, some infected subjects did show neurological effects. In fact, detection of some RNA of human-coronavirus in human brain samples clearly demonstrates that these respiratory pathogens are naturally neuroinvasive in J o u r n a l P r e -p r o o f humans and suggests that they establish a persistent infection in human CNS (Arbour et al., 2000) . Therefore, inflammation and oxidative stress systemic, induced by SARS-CoV-2 lung injury, could has effect in CNS causing neuronal dysfunction. The neuroinvasive potential of SARS-CoV2 may play a role in the respiratory failure of COVID-19 patients ./cache/cord-342204-9tgxijvn.txt ./txt/cord-342204-9tgxijvn.txt