id	sid	tid	token	lemma	pos
cord-018042-qt7055fw	1	1	key	key	NN
cord-018042-qt7055fw	1	2	:	:	:
cord-018042-qt7055fw	2	1	cord-018042-qt7055fw	cord-018042-qt7055fw	NNP
cord-018042-qt7055fw	2	2	authors	author	NNS
cord-018042-qt7055fw	2	3	:	:	:
cord-018042-qt7055fw	2	4	Müller	Müller	NNP
cord-018042-qt7055fw	2	5	,	,	,
cord-018042-qt7055fw	2	6	Marcus	Marcus	NNP
cord-018042-qt7055fw	2	7	;	;	:
cord-018042-qt7055fw	2	8	Campbell	Campbell	NNP
cord-018042-qt7055fw	2	9	,	,	,
cord-018042-qt7055fw	2	10	Iain	Iain	NNP
cord-018042-qt7055fw	2	11	L.	L.	NNP
cord-018042-qt7055fw	2	12	title	title	NN
cord-018042-qt7055fw	2	13	:	:	:
cord-018042-qt7055fw	2	14	Chemokine	Chemokine	NNP
cord-018042-qt7055fw	2	15	Actions	Actions	NNPS
cord-018042-qt7055fw	2	16	in	in	IN
cord-018042-qt7055fw	2	17	the	the	DT
cord-018042-qt7055fw	2	18	CNS	CNS	NNP
cord-018042-qt7055fw	2	19	:	:	:
cord-018042-qt7055fw	3	1	Insights	insight	NNS
cord-018042-qt7055fw	3	2	from	from	IN
cord-018042-qt7055fw	3	3	Transgenic	transgenic	JJ
cord-018042-qt7055fw	3	4	Mice	Mice	NNP
cord-018042-qt7055fw	3	5	date	date	NN
cord-018042-qt7055fw	3	6	:	:	:
cord-018042-qt7055fw	4	1	2008	2008	CD
cord-018042-qt7055fw	4	2	journal	journal	NNP
cord-018042-qt7055fw	4	3	:	:	:
cord-018042-qt7055fw	5	1	Central	Central	NNP
cord-018042-qt7055fw	5	2	Nervous	Nervous	NNP
cord-018042-qt7055fw	5	3	System	System	NNP
cord-018042-qt7055fw	5	4	Diseases	Diseases	NNPS
cord-018042-qt7055fw	5	5	and	and	CC
cord-018042-qt7055fw	5	6	Inflammation	inflammation	NN
cord-018042-qt7055fw	5	7	DOI	doi	NN
cord-018042-qt7055fw	5	8	:	:	:
cord-018042-qt7055fw	6	1	10.1007/978	10.1007/978	LS
cord-018042-qt7055fw	6	2	-	-	HYPH
cord-018042-qt7055fw	6	3	0	0	CD
cord-018042-qt7055fw	6	4	-	-	HYPH
cord-018042-qt7055fw	6	5	387	387	CD
cord-018042-qt7055fw	6	6	-	-	HYPH
cord-018042-qt7055fw	6	7	73894	73894	CD
cord-018042-qt7055fw	6	8	-	-	HYPH
cord-018042-qt7055fw	6	9	9_10	9_10	CD
cord-018042-qt7055fw	7	1	sha	sha	NNP
cord-018042-qt7055fw	7	2	:	:	:
cord-018042-qt7055fw	8	1	a6d9a305d3500b21b35037ebe9eca000f52ec9bc	a6d9a305d3500b21b35037ebe9eca000f52ec9bc	NNP
cord-018042-qt7055fw	8	2	doc_id	doc_id	CD
cord-018042-qt7055fw	8	3	:	:	:
cord-018042-qt7055fw	8	4	18042	18042	CD
cord-018042-qt7055fw	8	5	cord_uid	cord_uid	NNS
cord-018042-qt7055fw	8	6	:	:	:
cord-018042-qt7055fw	8	7	qt7055fw	qt7055fw	NNP
cord-018042-qt7055fw	9	1	Historically	historically	RB
cord-018042-qt7055fw	9	2	the	the	DT
cord-018042-qt7055fw	9	3	central	central	JJ
cord-018042-qt7055fw	9	4	nervous	nervous	JJ
cord-018042-qt7055fw	9	5	system	system	NN
cord-018042-qt7055fw	9	6	(	(	-LRB-
cord-018042-qt7055fw	9	7	CNS	CNS	NNP
cord-018042-qt7055fw	9	8	)	)	-RRB-
cord-018042-qt7055fw	9	9	has	have	VBZ
cord-018042-qt7055fw	9	10	been	be	VBN
cord-018042-qt7055fw	9	11	viewed	view	VBN
cord-018042-qt7055fw	9	12	as	as	IN
cord-018042-qt7055fw	9	13	a	a	DT
cord-018042-qt7055fw	9	14	relatively	relatively	RB
cord-018042-qt7055fw	9	15	immune	immune	JJ
cord-018042-qt7055fw	9	16	sheltered	sheltered	JJ
cord-018042-qt7055fw	9	17	tissue	tissue	NN
cord-018042-qt7055fw	9	18	.	.	.
cord-018042-qt7055fw	10	1	Under	under	IN
cord-018042-qt7055fw	10	2	physiological	physiological	JJ
cord-018042-qt7055fw	10	3	conditions	condition	NNS
cord-018042-qt7055fw	10	4	the	the	DT
cord-018042-qt7055fw	10	5	CNS	CNS	NNP
cord-018042-qt7055fw	10	6	is	be	VBZ
cord-018042-qt7055fw	10	7	devoid	devoid	JJ
cord-018042-qt7055fw	10	8	of	of	IN
cord-018042-qt7055fw	10	9	leukocytes	leukocyte	NNS
cord-018042-qt7055fw	10	10	,	,	,
cord-018042-qt7055fw	10	11	including	include	VBG
cord-018042-qt7055fw	10	12	professional	professional	JJ
cord-018042-qt7055fw	10	13	antigen	antigen	NN
cord-018042-qt7055fw	10	14	presenting	present	VBG
cord-018042-qt7055fw	10	15	cells	cell	NNS
cord-018042-qt7055fw	10	16	(	(	-LRB-
cord-018042-qt7055fw	10	17	APC	APC	NNP
cord-018042-qt7055fw	10	18	)	)	-RRB-
cord-018042-qt7055fw	10	19	,	,	,
cord-018042-qt7055fw	10	20	is	be	VBZ
cord-018042-qt7055fw	10	21	deficient	deficient	JJ
cord-018042-qt7055fw	10	22	in	in	IN
cord-018042-qt7055fw	10	23	key	key	JJ
cord-018042-qt7055fw	10	24	immune	immune	JJ
cord-018042-qt7055fw	10	25	accessory	accessory	NN
cord-018042-qt7055fw	10	26	molecules	molecule	NNS
cord-018042-qt7055fw	10	27	such	such	JJ
cord-018042-qt7055fw	10	28	as	as	IN
cord-018042-qt7055fw	10	29	major	major	JJ
cord-018042-qt7055fw	10	30	histocompatibility	histocompatibility	NN
cord-018042-qt7055fw	10	31	molecules	molecule	NNS
cord-018042-qt7055fw	10	32	(	(	-LRB-
cord-018042-qt7055fw	10	33	MHC	MHC	NNP
cord-018042-qt7055fw	10	34	)	)	-RRB-
cord-018042-qt7055fw	10	35	and	and	CC
cord-018042-qt7055fw	10	36	is	be	VBZ
cord-018042-qt7055fw	10	37	protected	protect	VBN
cord-018042-qt7055fw	10	38	by	by	IN
cord-018042-qt7055fw	10	39	an	an	DT
cord-018042-qt7055fw	10	40	effective	effective	JJ
cord-018042-qt7055fw	10	41	blood	blood	NN
cord-018042-qt7055fw	10	42	brain	brain	NN
cord-018042-qt7055fw	10	43	barrier	barrier	NN
cord-018042-qt7055fw	10	44	.	.	.
cord-018042-qt7055fw	11	1	Significantly	significantly	RB
cord-018042-qt7055fw	11	2	,	,	,
cord-018042-qt7055fw	11	3	however	however	RB
cord-018042-qt7055fw	11	4	,	,	,
cord-018042-qt7055fw	11	5	in	in	IN
cord-018042-qt7055fw	11	6	numerous	numerous	JJ
cord-018042-qt7055fw	11	7	pathological	pathological	JJ
cord-018042-qt7055fw	11	8	states	state	NNS
cord-018042-qt7055fw	11	9	including	include	VBG
cord-018042-qt7055fw	11	10	infectious	infectious	JJ
cord-018042-qt7055fw	11	11	diseases	disease	NNS
cord-018042-qt7055fw	11	12	and	and	CC
cord-018042-qt7055fw	11	13	autoimmune	autoimmune	JJ
cord-018042-qt7055fw	11	14	disorders	disorder	NNS
cord-018042-qt7055fw	11	15	(	(	-LRB-
cord-018042-qt7055fw	11	16	e.g.	e.g.	IN
cord-018042-qt7055fw	11	17	multiple	multiple	JJ
cord-018042-qt7055fw	11	18	sclerosis	sclerosis	NN
cord-018042-qt7055fw	11	19	)	)	-RRB-
cord-018042-qt7055fw	11	20	immune	immune	JJ
cord-018042-qt7055fw	11	21	cells	cell	NNS
cord-018042-qt7055fw	11	22	are	be	VBP
cord-018042-qt7055fw	11	23	effectively	effectively	RB
cord-018042-qt7055fw	11	24	recruited	recruit	VBN
cord-018042-qt7055fw	11	25	to	to	IN
cord-018042-qt7055fw	11	26	and	and	CC
cord-018042-qt7055fw	11	27	infiltrate	infiltrate	VB
cord-018042-qt7055fw	11	28	in	in	IN
cord-018042-qt7055fw	11	29	the	the	DT
cord-018042-qt7055fw	11	30	CNS	CNS	NNP
cord-018042-qt7055fw	11	31	.	.	.
cord-018042-qt7055fw	12	1	This	this	DT
cord-018042-qt7055fw	12	2	immune	immune	JJ
cord-018042-qt7055fw	12	3	response	response	NN
cord-018042-qt7055fw	12	4	can	can	MD
cord-018042-qt7055fw	12	5	be	be	VB
cord-018042-qt7055fw	12	6	a	a	DT
cord-018042-qt7055fw	12	7	two	two	CD
cord-018042-qt7055fw	12	8	-	-	HYPH
cord-018042-qt7055fw	12	9	edged	edge	VBN
cord-018042-qt7055fw	12	10	sword	sword	NN
cord-018042-qt7055fw	12	11	required	require	VBN
cord-018042-qt7055fw	12	12	on	on	IN
cord-018042-qt7055fw	12	13	the	the	DT
cord-018042-qt7055fw	12	14	one	one	CD
cord-018042-qt7055fw	12	15	hand	hand	NN
cord-018042-qt7055fw	12	16	to	to	TO
cord-018042-qt7055fw	12	17	control	control	VB
cord-018042-qt7055fw	12	18	infection	infection	NN
cord-018042-qt7055fw	12	19	and	and	CC
cord-018042-qt7055fw	12	20	facilitate	facilitate	VB
cord-018042-qt7055fw	12	21	tissue	tissue	NN
cord-018042-qt7055fw	12	22	repair	repair	NN
cord-018042-qt7055fw	12	23	and	and	CC
cord-018042-qt7055fw	12	24	regeneration	regeneration	NN
cord-018042-qt7055fw	12	25	but	but	CC
cord-018042-qt7055fw	12	26	on	on	IN
cord-018042-qt7055fw	12	27	the	the	DT
cord-018042-qt7055fw	12	28	other	other	JJ
cord-018042-qt7055fw	12	29	causing	cause	VBG
cord-018042-qt7055fw	12	30	tissue	tissue	NN
cord-018042-qt7055fw	12	31	injury	injury	NN
cord-018042-qt7055fw	12	32	that	that	WDT
cord-018042-qt7055fw	12	33	can	can	MD
cord-018042-qt7055fw	12	34	result	result	VB
cord-018042-qt7055fw	12	35	in	in	IN
cord-018042-qt7055fw	12	36	life	life	NN
cord-018042-qt7055fw	12	37	threatening	threaten	VBG
cord-018042-qt7055fw	12	38	complications	complication	NNS
cord-018042-qt7055fw	12	39	.	.	.
cord-018042-qt7055fw	13	1	Therefore	therefore	RB
cord-018042-qt7055fw	13	2	,	,	,
cord-018042-qt7055fw	13	3	understanding	understand	VBG
cord-018042-qt7055fw	13	4	the	the	DT
cord-018042-qt7055fw	13	5	mechanisms	mechanism	NNS
cord-018042-qt7055fw	13	6	that	that	WDT
cord-018042-qt7055fw	13	7	control	control	VBP
cord-018042-qt7055fw	13	8	the	the	DT
cord-018042-qt7055fw	13	9	trafficking	trafficking	NN
cord-018042-qt7055fw	13	10	of	of	IN
cord-018042-qt7055fw	13	11	leukocytes	leukocyte	NNS
cord-018042-qt7055fw	13	12	to	to	IN
cord-018042-qt7055fw	13	13	the	the	DT
cord-018042-qt7055fw	13	14	CNS	CNS	NNP
cord-018042-qt7055fw	13	15	and	and	CC
cord-018042-qt7055fw	13	16	the	the	DT
cord-018042-qt7055fw	13	17	subsequent	subsequent	JJ
cord-018042-qt7055fw	13	18	interactions	interaction	NNS
cord-018042-qt7055fw	13	19	between	between	IN
cord-018042-qt7055fw	13	20	these	these	DT
cord-018042-qt7055fw	13	21	cells	cell	NNS
cord-018042-qt7055fw	13	22	that	that	WDT
cord-018042-qt7055fw	13	23	contribute	contribute	VBP
cord-018042-qt7055fw	13	24	to	to	IN
cord-018042-qt7055fw	13	25	tissue	tissue	NN
cord-018042-qt7055fw	13	26	injury	injury	NN
cord-018042-qt7055fw	13	27	has	have	VBZ
cord-018042-qt7055fw	13	28	significant	significant	JJ
cord-018042-qt7055fw	13	29	implications	implication	NNS
cord-018042-qt7055fw	13	30	.	.	.
cord-018042-qt7055fw	14	1	chemokines	chemokine	NNS
cord-018042-qt7055fw	14	2	following	follow	VBG
cord-018042-qt7055fw	14	3	such	such	JJ
cord-018042-qt7055fw	14	4	insults	insult	NNS
cord-018042-qt7055fw	14	5	can	can	MD
cord-018042-qt7055fw	14	6	be	be	VB
cord-018042-qt7055fw	14	7	mediated	mediate	VBN
cord-018042-qt7055fw	14	8	by	by	IN
cord-018042-qt7055fw	14	9	a	a	DT
cord-018042-qt7055fw	14	10	number	number	NN
cord-018042-qt7055fw	14	11	of	of	IN
cord-018042-qt7055fw	14	12	factors	factor	NNS
cord-018042-qt7055fw	14	13	including	include	VBG
cord-018042-qt7055fw	14	14	microbial	microbial	JJ
cord-018042-qt7055fw	14	15	products	product	NNS
cord-018042-qt7055fw	14	16	(	(	-LRB-
cord-018042-qt7055fw	14	17	e.g.	e.g.	RB
cord-018042-qt7055fw	14	18	,	,	,
cord-018042-qt7055fw	14	19	LPS	LPS	NNP
cord-018042-qt7055fw	14	20	)	)	-RRB-
cord-018042-qt7055fw	14	21	and	and	CC
cord-018042-qt7055fw	14	22	host	host	NN
cord-018042-qt7055fw	14	23	defense	defense	NN
cord-018042-qt7055fw	14	24	molecules	molecule	NNS
cord-018042-qt7055fw	14	25	such	such	JJ
cord-018042-qt7055fw	14	26	as	as	IN
cord-018042-qt7055fw	14	27	cytokines	cytokine	NNS
cord-018042-qt7055fw	14	28	(	(	-LRB-
cord-018042-qt7055fw	14	29	e.g.	e.g.	RB
cord-018042-qt7055fw	14	30	,	,	,
cord-018042-qt7055fw	14	31	IL-1	IL-1	NNP
cord-018042-qt7055fw	14	32	,	,	,
cord-018042-qt7055fw	14	33	IFN	IFN	NNP
cord-018042-qt7055fw	14	34	-	-	HYPH
cord-018042-qt7055fw	14	35	γ	γ	NNP
cord-018042-qt7055fw	14	36	and	and	CC
cord-018042-qt7055fw	14	37	TNF	TNF	NNP
cord-018042-qt7055fw	14	38	)	)	-RRB-
cord-018042-qt7055fw	14	39	.	.	.
cord-018042-qt7055fw	15	1	Cells	cell	NNS
cord-018042-qt7055fw	15	2	intrinsic	intrinsic	JJ
cord-018042-qt7055fw	15	3	to	to	IN
cord-018042-qt7055fw	15	4	the	the	DT
cord-018042-qt7055fw	15	5	nervous	nervous	JJ
cord-018042-qt7055fw	15	6	system	system	NN
cord-018042-qt7055fw	15	7	,	,	,
cord-018042-qt7055fw	15	8	including	include	VBG
cord-018042-qt7055fw	15	9	neurons	neuron	NNS
cord-018042-qt7055fw	15	10	,	,	,
cord-018042-qt7055fw	15	11	the	the	DT
cord-018042-qt7055fw	15	12	macroglia	macroglia	NNP
cord-018042-qt7055fw	15	13	and	and	CC
cord-018042-qt7055fw	15	14	microglia	microglia	NNP
cord-018042-qt7055fw	15	15	,	,	,
cord-018042-qt7055fw	15	16	all	all	DT
cord-018042-qt7055fw	15	17	have	have	VBP
cord-018042-qt7055fw	15	18	the	the	DT
cord-018042-qt7055fw	15	19	ability	ability	NN
cord-018042-qt7055fw	15	20	to	to	TO
cord-018042-qt7055fw	15	21	produce	produce	VB
cord-018042-qt7055fw	15	22	different	different	JJ
cord-018042-qt7055fw	15	23	chemokines	chemokine	NNS
cord-018042-qt7055fw	15	24	(	(	-LRB-
cord-018042-qt7055fw	15	25	reviewed	review	VBN
cord-018042-qt7055fw	15	26	in	in	IN
cord-018042-qt7055fw	15	27	Asensio	Asensio	NNP
cord-018042-qt7055fw	15	28	and	and	CC
cord-018042-qt7055fw	15	29	Campbell	Campbell	NNP
cord-018042-qt7055fw	15	30	(	(	-LRB-
cord-018042-qt7055fw	15	31	1999	1999	CD
cord-018042-qt7055fw	15	32	)	)	-RRB-
cord-018042-qt7055fw	15	33	and	and	CC
cord-018042-qt7055fw	15	34	Ubogu	Ubogu	NNP
cord-018042-qt7055fw	15	35	et	et	NNP
cord-018042-qt7055fw	15	36	al	al	NNP
cord-018042-qt7055fw	15	37	.	.	.
cord-018042-qt7055fw	16	1	(	(	-LRB-
cord-018042-qt7055fw	16	2	2006	2006	CD
cord-018042-qt7055fw	16	3	)	)	-RRB-
cord-018042-qt7055fw	16	4	)	)	-RRB-
cord-018042-qt7055fw	16	5	.	.	.
cord-018042-qt7055fw	17	1	Moreover	moreover	RB
cord-018042-qt7055fw	17	2	,	,	,
cord-018042-qt7055fw	17	3	the	the	DT
cord-018042-qt7055fw	17	4	surfaces	surface	NNS
cord-018042-qt7055fw	17	5	of	of	IN
cord-018042-qt7055fw	17	6	these	these	DT
cord-018042-qt7055fw	17	7	same	same	JJ
cord-018042-qt7055fw	17	8	cells	cell	NNS
cord-018042-qt7055fw	17	9	are	be	VBP
cord-018042-qt7055fw	17	10	decorated	decorate	VBN
cord-018042-qt7055fw	17	11	with	with	IN
cord-018042-qt7055fw	17	12	a	a	DT
cord-018042-qt7055fw	17	13	variety	variety	NN
cord-018042-qt7055fw	17	14	of	of	IN
cord-018042-qt7055fw	17	15	different	different	JJ
cord-018042-qt7055fw	17	16	chemokine	chemokine	NN
cord-018042-qt7055fw	17	17	receptors	receptor	NNS
cord-018042-qt7055fw	17	18	.	.	.
cord-018042-qt7055fw	18	1	Thus	thus	RB
cord-018042-qt7055fw	18	2	,	,	,
cord-018042-qt7055fw	18	3	the	the	DT
cord-018042-qt7055fw	18	4	CNS	CNS	NNP
cord-018042-qt7055fw	18	5	seemingly	seemingly	RB
cord-018042-qt7055fw	18	6	has	have	VBZ
cord-018042-qt7055fw	18	7	its	-PRON-	PRP$
cord-018042-qt7055fw	18	8	own	own	JJ
cord-018042-qt7055fw	18	9	chemokine	chemokine	NN
cord-018042-qt7055fw	18	10	ligand	ligand	NN
cord-018042-qt7055fw	18	11	/	/	SYM
cord-018042-qt7055fw	18	12	receptor	receptor	NN
cord-018042-qt7055fw	18	13	network	network	NN
cord-018042-qt7055fw	18	14	,	,	,
cord-018042-qt7055fw	18	15	which	which	WDT
cord-018042-qt7055fw	18	16	is	be	VBZ
cord-018042-qt7055fw	18	17	consistent	consistent	JJ
cord-018042-qt7055fw	18	18	with	with	IN
cord-018042-qt7055fw	18	19	the	the	DT
cord-018042-qt7055fw	18	20	growing	grow	VBG
cord-018042-qt7055fw	18	21	awareness	awareness	NN
cord-018042-qt7055fw	18	22	that	that	WDT
cord-018042-qt7055fw	18	23	the	the	DT
cord-018042-qt7055fw	18	24	function	function	NN
cord-018042-qt7055fw	18	25	of	of	IN
cord-018042-qt7055fw	18	26	chemokines	chemokine	NNS
cord-018042-qt7055fw	18	27	could	could	MD
cord-018042-qt7055fw	18	28	extend	extend	VB
cord-018042-qt7055fw	18	29	well	well	RB
cord-018042-qt7055fw	18	30	beyond	beyond	IN
cord-018042-qt7055fw	18	31	the	the	DT
cord-018042-qt7055fw	18	32	regulation	regulation	NN
cord-018042-qt7055fw	18	33	of	of	IN
cord-018042-qt7055fw	18	34	leukocyte	leukocyte	NN
cord-018042-qt7055fw	18	35	trafficking	trafficking	NN
cord-018042-qt7055fw	18	36	in	in	IN
cord-018042-qt7055fw	18	37	the	the	DT
cord-018042-qt7055fw	18	38	brain	brain	NN
cord-018042-qt7055fw	18	39	(	(	-LRB-
cord-018042-qt7055fw	18	40	Asensio	Asensio	NNP
cord-018042-qt7055fw	18	41	and	and	CC
cord-018042-qt7055fw	18	42	Campbell	Campbell	NNP
cord-018042-qt7055fw	18	43	,	,	,
cord-018042-qt7055fw	18	44	1999	1999	CD
cord-018042-qt7055fw	18	45	;	;	:
cord-018042-qt7055fw	18	46	Mennicken	Mennicken	NNP
cord-018042-qt7055fw	18	47	et	et	NNP
cord-018042-qt7055fw	18	48	al	al	NNP
cord-018042-qt7055fw	18	49	.	.	NNP
cord-018042-qt7055fw	18	50	,	,	,
cord-018042-qt7055fw	18	51	1999	1999	CD
cord-018042-qt7055fw	18	52	)	)	-RRB-
cord-018042-qt7055fw	18	53	.	.	.
cord-018042-qt7055fw	19	1	So	so	RB
cord-018042-qt7055fw	19	2	it	-PRON-	PRP
cord-018042-qt7055fw	19	3	can	can	MD
cord-018042-qt7055fw	19	4	be	be	VB
cord-018042-qt7055fw	19	5	seen	see	VBN
cord-018042-qt7055fw	19	6	that	that	IN
cord-018042-qt7055fw	19	7	the	the	DT
cord-018042-qt7055fw	19	8	CNS	CNS	NNP
cord-018042-qt7055fw	19	9	biology	biology	NN
cord-018042-qt7055fw	19	10	of	of	IN
cord-018042-qt7055fw	19	11	the	the	DT
cord-018042-qt7055fw	19	12	chemokines	chemokine	NNS
cord-018042-qt7055fw	19	13	is	be	VBZ
cord-018042-qt7055fw	19	14	likely	likely	JJ
cord-018042-qt7055fw	19	15	to	to	TO
cord-018042-qt7055fw	19	16	extend	extend	VB
cord-018042-qt7055fw	19	17	well	well	RB
cord-018042-qt7055fw	19	18	beyond	beyond	IN
cord-018042-qt7055fw	19	19	the	the	DT
cord-018042-qt7055fw	19	20	singular	singular	JJ
cord-018042-qt7055fw	19	21	function	function	NN
cord-018042-qt7055fw	19	22	of	of	IN
cord-018042-qt7055fw	19	23	leukocyte	leukocyte	NN
cord-018042-qt7055fw	19	24	chemotaxis	chemotaxis	NN
cord-018042-qt7055fw	19	25	.	.	.
cord-018042-qt7055fw	20	1	A	a	DT
cord-018042-qt7055fw	20	2	number	number	NN
cord-018042-qt7055fw	20	3	of	of	IN
cord-018042-qt7055fw	20	4	important	important	JJ
cord-018042-qt7055fw	20	5	questions	question	NNS
cord-018042-qt7055fw	20	6	are	be	VBP
cord-018042-qt7055fw	20	7	therefore	therefore	RB
cord-018042-qt7055fw	20	8	raised	raise	VBN
cord-018042-qt7055fw	20	9	concerning	concern	VBG
cord-018042-qt7055fw	20	10	the	the	DT
cord-018042-qt7055fw	20	11	functions	function	NNS
cord-018042-qt7055fw	20	12	of	of	IN
cord-018042-qt7055fw	20	13	the	the	DT
cord-018042-qt7055fw	20	14	chemokines	chemokine	NNS
cord-018042-qt7055fw	20	15	in	in	IN
cord-018042-qt7055fw	20	16	the	the	DT
cord-018042-qt7055fw	20	17	CNS	CNS	NNP
cord-018042-qt7055fw	20	18	.	.	.
cord-018042-qt7055fw	21	1	Some	some	DT
cord-018042-qt7055fw	21	2	key	key	JJ
cord-018042-qt7055fw	21	3	questions	question	NNS
cord-018042-qt7055fw	21	4	include	include	VBP
cord-018042-qt7055fw	21	5	:	:	:
cord-018042-qt7055fw	21	6	(	(	-LRB-
cord-018042-qt7055fw	21	7	1	1	LS
cord-018042-qt7055fw	21	8	)	)	-RRB-
cord-018042-qt7055fw	21	9	Do	do	VB
cord-018042-qt7055fw	21	10	the	the	DT
cord-018042-qt7055fw	21	11	presence	presence	NN
cord-018042-qt7055fw	21	12	of	of	IN
cord-018042-qt7055fw	21	13	chemokines	chemokine	NNS
cord-018042-qt7055fw	21	14	in	in	IN
cord-018042-qt7055fw	21	15	different	different	JJ
cord-018042-qt7055fw	21	16	disordered	disordered	JJ
cord-018042-qt7055fw	21	17	states	state	NNS
cord-018042-qt7055fw	21	18	reflect	reflect	VBP
cord-018042-qt7055fw	21	19	their	-PRON-	PRP$
cord-018042-qt7055fw	21	20	primary	primary	JJ
cord-018042-qt7055fw	21	21	involvement	involvement	NN
cord-018042-qt7055fw	21	22	or	or	CC
cord-018042-qt7055fw	21	23	is	be	VBZ
cord-018042-qt7055fw	21	24	an	an	DT
cord-018042-qt7055fw	21	25	epiphenomenon	epiphenomenon	NN
cord-018042-qt7055fw	21	26	?	?	.
cord-018042-qt7055fw	22	1	(	(	-LRB-
cord-018042-qt7055fw	22	2	2	2	LS
cord-018042-qt7055fw	22	3	)	)	-RRB-
cord-018042-qt7055fw	22	4	Is	be	VBZ
cord-018042-qt7055fw	22	5	there	there	EX
cord-018042-qt7055fw	22	6	a	a	DT
cord-018042-qt7055fw	22	7	cause	cause	NN
cord-018042-qt7055fw	22	8	and	and	CC
cord-018042-qt7055fw	22	9	effect	effect	NN
cord-018042-qt7055fw	22	10	relationship	relationship	NN
cord-018042-qt7055fw	22	11	between	between	IN
cord-018042-qt7055fw	22	12	the	the	DT
cord-018042-qt7055fw	22	13	production	production	NN
cord-018042-qt7055fw	22	14	of	of	IN
cord-018042-qt7055fw	22	15	a	a	DT
cord-018042-qt7055fw	22	16	particular	particular	JJ
cord-018042-qt7055fw	22	17	chemokine	chemokine	NN
cord-018042-qt7055fw	22	18	(	(	-LRB-
cord-018042-qt7055fw	22	19	or	or	CC
cord-018042-qt7055fw	22	20	chemokines	chemokine	NNS
cord-018042-qt7055fw	22	21	)	)	-RRB-
cord-018042-qt7055fw	22	22	and	and	CC
cord-018042-qt7055fw	22	23	the	the	DT
cord-018042-qt7055fw	22	24	development	development	NN
cord-018042-qt7055fw	22	25	of	of	IN
cord-018042-qt7055fw	22	26	specific	specific	JJ
cord-018042-qt7055fw	22	27	molecular	molecular	JJ
cord-018042-qt7055fw	22	28	and	and	CC
cord-018042-qt7055fw	22	29	cellular	cellular	JJ
cord-018042-qt7055fw	22	30	neuropathological	neuropathological	JJ
cord-018042-qt7055fw	22	31	alterations	alteration	NNS
cord-018042-qt7055fw	22	32	?	?	.
cord-018042-qt7055fw	23	1	(	(	-LRB-
cord-018042-qt7055fw	23	2	3	3	LS
cord-018042-qt7055fw	23	3	)	)	-RRB-
cord-018042-qt7055fw	24	1	What	what	WP
cord-018042-qt7055fw	24	2	are	be	VBP
cord-018042-qt7055fw	24	3	the	the	DT
cord-018042-qt7055fw	24	4	mechanisms	mechanism	NNS
cord-018042-qt7055fw	24	5	that	that	WDT
cord-018042-qt7055fw	24	6	underlie	underlie	VBP
cord-018042-qt7055fw	24	7	chemokinemediated	chemokinemediated	JJ
cord-018042-qt7055fw	24	8	actions	action	NNS
cord-018042-qt7055fw	24	9	in	in	IN
cord-018042-qt7055fw	24	10	the	the	DT
cord-018042-qt7055fw	24	11	CNS	CNS	NNP
cord-018042-qt7055fw	24	12	?	?	.
cord-018042-qt7055fw	25	1	(	(	-LRB-
cord-018042-qt7055fw	25	2	4	4	LS
cord-018042-qt7055fw	25	3	)	)	-RRB-
cord-018042-qt7055fw	25	4	Could	Could	MD
cord-018042-qt7055fw	25	5	manipulation	manipulation	NN
cord-018042-qt7055fw	25	6	of	of	IN
cord-018042-qt7055fw	25	7	the	the	DT
cord-018042-qt7055fw	25	8	chemokines	chemokine	NNS
cord-018042-qt7055fw	25	9	or	or	CC
cord-018042-qt7055fw	25	10	their	-PRON-	PRP$
cord-018042-qt7055fw	25	11	receptors	receptor	NNS
cord-018042-qt7055fw	25	12	be	be	VB
cord-018042-qt7055fw	25	13	used	use	VBN
cord-018042-qt7055fw	25	14	as	as	IN
cord-018042-qt7055fw	25	15	a	a	DT
cord-018042-qt7055fw	25	16	rational	rational	JJ
cord-018042-qt7055fw	25	17	means	mean	NNS
cord-018042-qt7055fw	25	18	for	for	IN
cord-018042-qt7055fw	25	19	therapeutic	therapeutic	JJ
cord-018042-qt7055fw	25	20	intervention	intervention	NN
cord-018042-qt7055fw	25	21	?	?	.
cord-018042-qt7055fw	26	1	To	to	TO
cord-018042-qt7055fw	26	2	begin	begin	VB
cord-018042-qt7055fw	26	3	to	to	TO
cord-018042-qt7055fw	26	4	address	address	VB
cord-018042-qt7055fw	26	5	these	these	DT
cord-018042-qt7055fw	26	6	questions	question	NNS
cord-018042-qt7055fw	26	7	experimental	experimental	JJ
cord-018042-qt7055fw	26	8	approaches	approach	NNS
cord-018042-qt7055fw	26	9	are	be	VBP
cord-018042-qt7055fw	26	10	required	require	VBN
cord-018042-qt7055fw	26	11	that	that	WDT
cord-018042-qt7055fw	26	12	are	be	VBP
cord-018042-qt7055fw	26	13	non	non	JJ
cord-018042-qt7055fw	26	14	-	-	JJ
cord-018042-qt7055fw	26	15	invasive	invasive	JJ
cord-018042-qt7055fw	26	16	and	and	CC
cord-018042-qt7055fw	26	17	organism	organism	NN
cord-018042-qt7055fw	26	18	-	-	HYPH
cord-018042-qt7055fw	26	19	based	base	VBN
cord-018042-qt7055fw	26	20	.	.	.
cord-018042-qt7055fw	27	1	Of	of	IN
cord-018042-qt7055fw	27	2	particular	particular	JJ
cord-018042-qt7055fw	27	3	significance	significance	NN
cord-018042-qt7055fw	27	4	in	in	IN
cord-018042-qt7055fw	27	5	this	this	DT
cord-018042-qt7055fw	27	6	regard	regard	NN
cord-018042-qt7055fw	27	7	has	have	VBZ
cord-018042-qt7055fw	27	8	been	be	VBN
cord-018042-qt7055fw	27	9	the	the	DT
cord-018042-qt7055fw	27	10	application	application	NN
cord-018042-qt7055fw	27	11	of	of	IN
cord-018042-qt7055fw	27	12	genetic	genetic	JJ
cord-018042-qt7055fw	27	13	engineering	engineering	NN
cord-018042-qt7055fw	27	14	technology	technology	NN
cord-018042-qt7055fw	27	15	that	that	WDT
cord-018042-qt7055fw	27	16	has	have	VBZ
cord-018042-qt7055fw	27	17	permitted	permit	VBN
cord-018042-qt7055fw	27	18	the	the	DT
cord-018042-qt7055fw	27	19	germline	germline	JJ
cord-018042-qt7055fw	27	20	transmission	transmission	NN
cord-018042-qt7055fw	27	21	of	of	IN
cord-018042-qt7055fw	27	22	foreign	foreign	JJ
cord-018042-qt7055fw	27	23	genes	gene	NNS
cord-018042-qt7055fw	27	24	(	(	-LRB-
cord-018042-qt7055fw	27	25	transgenes	transgene	NNS
cord-018042-qt7055fw	27	26	)	)	-RRB-
cord-018042-qt7055fw	27	27	in	in	IN
cord-018042-qt7055fw	27	28	the	the	DT
cord-018042-qt7055fw	27	29	mouse	mouse	NN
cord-018042-qt7055fw	27	30	.	.	.
cord-018042-qt7055fw	28	1	This	this	DT
cord-018042-qt7055fw	28	2	is	be	VBZ
cord-018042-qt7055fw	28	3	accomplished	accomplish	VBN
cord-018042-qt7055fw	28	4	via	via	IN
cord-018042-qt7055fw	28	5	a	a	DT
cord-018042-qt7055fw	28	6	fusion	fusion	NN
cord-018042-qt7055fw	28	7	gene	gene	NN
cord-018042-qt7055fw	28	8	construct	construct	NN
cord-018042-qt7055fw	28	9	(	(	-LRB-
cord-018042-qt7055fw	28	10	transgene	transgene	NN
cord-018042-qt7055fw	28	11	)	)	-RRB-
cord-018042-qt7055fw	28	12	in	in	IN
cord-018042-qt7055fw	28	13	which	which	WDT
cord-018042-qt7055fw	28	14	the	the	DT
cord-018042-qt7055fw	28	15	gene	gene	NN
cord-018042-qt7055fw	28	16	of	of	IN
cord-018042-qt7055fw	28	17	interest	interest	NN
cord-018042-qt7055fw	28	18	is	be	VBZ
cord-018042-qt7055fw	28	19	placed	place	VBN
cord-018042-qt7055fw	28	20	under	under	IN
cord-018042-qt7055fw	28	21	the	the	DT
cord-018042-qt7055fw	28	22	transcriptional	transcriptional	JJ
cord-018042-qt7055fw	28	23	control	control	NN
cord-018042-qt7055fw	28	24	of	of	IN
cord-018042-qt7055fw	28	25	a	a	DT
cord-018042-qt7055fw	28	26	cell	cell	NN
cord-018042-qt7055fw	28	27	-	-	HYPH
cord-018042-qt7055fw	28	28	specific	specific	JJ
cord-018042-qt7055fw	28	29	promoter	promoter	NN
cord-018042-qt7055fw	28	30	.	.	.
cord-018042-qt7055fw	29	1	The	the	DT
cord-018042-qt7055fw	29	2	transgene	transgene	NN
cord-018042-qt7055fw	29	3	is	be	VBZ
cord-018042-qt7055fw	29	4	then	then	RB
cord-018042-qt7055fw	29	5	introduced	introduce	VBN
cord-018042-qt7055fw	29	6	(	(	-LRB-
cord-018042-qt7055fw	29	7	most	most	RBS
cord-018042-qt7055fw	29	8	commonly	commonly	RB
cord-018042-qt7055fw	29	9	by	by	IN
cord-018042-qt7055fw	29	10	microinjection	microinjection	NN
cord-018042-qt7055fw	29	11	)	)	-RRB-
cord-018042-qt7055fw	29	12	into	into	IN
cord-018042-qt7055fw	29	13	the	the	DT
cord-018042-qt7055fw	29	14	pronucleus	pronucleus	NN
cord-018042-qt7055fw	29	15	of	of	IN
cord-018042-qt7055fw	29	16	fertilized	fertilize	VBN
cord-018042-qt7055fw	29	17	eggs	egg	NNS
cord-018042-qt7055fw	29	18	,	,	,
cord-018042-qt7055fw	29	19	which	which	WDT
cord-018042-qt7055fw	29	20	are	be	VBP
cord-018042-qt7055fw	29	21	then	then	RB
cord-018042-qt7055fw	29	22	implanted	implant	VBN
cord-018042-qt7055fw	29	23	in	in	IN
cord-018042-qt7055fw	29	24	the	the	DT
cord-018042-qt7055fw	29	25	oviduct	oviduct	NN
cord-018042-qt7055fw	29	26	of	of	IN
cord-018042-qt7055fw	29	27	pseudopregnant	pseudopregnant	JJ
cord-018042-qt7055fw	29	28	recipient	recipient	NN
cord-018042-qt7055fw	29	29	mice	mouse	NNS
cord-018042-qt7055fw	29	30	.	.	.
cord-018042-qt7055fw	30	1	The	the	DT
cord-018042-qt7055fw	30	2	transgenic	transgenic	JJ
cord-018042-qt7055fw	30	3	approach	approach	NN
cord-018042-qt7055fw	30	4	has	have	VBZ
cord-018042-qt7055fw	30	5	a	a	DT
cord-018042-qt7055fw	30	6	number	number	NN
cord-018042-qt7055fw	30	7	of	of	IN
cord-018042-qt7055fw	30	8	advantages	advantage	NNS
cord-018042-qt7055fw	30	9	over	over	IN
cord-018042-qt7055fw	30	10	other	other	JJ
cord-018042-qt7055fw	30	11	approaches	approach	NNS
cord-018042-qt7055fw	30	12	such	such	JJ
cord-018042-qt7055fw	30	13	as	as	IN
cord-018042-qt7055fw	30	14	intracerebral	intracerebral	JJ
cord-018042-qt7055fw	30	15	infusion	infusion	NN
cord-018042-qt7055fw	30	16	or	or	CC
cord-018042-qt7055fw	30	17	in	in	IN
cord-018042-qt7055fw	30	18	vitro	vitro	FW
cord-018042-qt7055fw	30	19	cell	cell	NN
cord-018042-qt7055fw	30	20	culture	culture	NN
cord-018042-qt7055fw	30	21	.	.	.
cord-018042-qt7055fw	31	1	Transgenic	transgenic	JJ
cord-018042-qt7055fw	31	2	modeling	modeling	NN
cord-018042-qt7055fw	31	3	allows	allow	VBZ
cord-018042-qt7055fw	31	4	the	the	DT
cord-018042-qt7055fw	31	5	prolonged	prolonged	JJ
cord-018042-qt7055fw	31	6	,	,	,
cord-018042-qt7055fw	31	7	reproducible	reproducible	JJ
cord-018042-qt7055fw	31	8	delivery	delivery	NN
cord-018042-qt7055fw	31	9	of	of	IN
cord-018042-qt7055fw	31	10	a	a	DT
cord-018042-qt7055fw	31	11	specific	specific	JJ
cord-018042-qt7055fw	31	12	pure	pure	JJ
cord-018042-qt7055fw	31	13	protein	protein	NN
cord-018042-qt7055fw	31	14	to	to	IN
cord-018042-qt7055fw	31	15	specific	specific	JJ
cord-018042-qt7055fw	31	16	cells	cell	NNS
cord-018042-qt7055fw	31	17	in	in	IN
cord-018042-qt7055fw	31	18	the	the	DT
cord-018042-qt7055fw	31	19	intact	intact	JJ
cord-018042-qt7055fw	31	20	CNS	CNS	NNP
cord-018042-qt7055fw	31	21	.	.	.
cord-018042-qt7055fw	32	1	The	the	DT
cord-018042-qt7055fw	32	2	actions	action	NNS
cord-018042-qt7055fw	32	3	of	of	IN
cord-018042-qt7055fw	32	4	the	the	DT
cord-018042-qt7055fw	32	5	transgene	transgene	NN
cord-018042-qt7055fw	32	6	product	product	NN
cord-018042-qt7055fw	32	7	are	be	VBP
cord-018042-qt7055fw	32	8	exerted	exert	VBN
cord-018042-qt7055fw	32	9	and	and	CC
cord-018042-qt7055fw	32	10	can	can	MD
cord-018042-qt7055fw	32	11	be	be	VB
cord-018042-qt7055fw	32	12	assessed	assess	VBN
cord-018042-qt7055fw	32	13	in	in	IN
cord-018042-qt7055fw	32	14	a	a	DT
cord-018042-qt7055fw	32	15	milieu	milieu	NN
cord-018042-qt7055fw	32	16	where	where	WRB
cord-018042-qt7055fw	32	17	the	the	DT
cord-018042-qt7055fw	32	18	anatomic	anatomic	JJ
cord-018042-qt7055fw	32	19	and	and	CC
cord-018042-qt7055fw	32	20	physiologic	physiologic	JJ
cord-018042-qt7055fw	32	21	interactions	interaction	NNS
cord-018042-qt7055fw	32	22	of	of	IN
cord-018042-qt7055fw	32	23	the	the	DT
cord-018042-qt7055fw	32	24	CNS	CNS	NNP
cord-018042-qt7055fw	32	25	are	be	VBP
cord-018042-qt7055fw	32	26	preserved	preserve	VBN
cord-018042-qt7055fw	32	27	.	.	.
cord-018042-qt7055fw	33	1	Moreover	moreover	RB
cord-018042-qt7055fw	33	2	,	,	,
cord-018042-qt7055fw	33	3	individual	individual	JJ
cord-018042-qt7055fw	33	4	lines	line	NNS
cord-018042-qt7055fw	33	5	of	of	IN
cord-018042-qt7055fw	33	6	mice	mouse	NNS
cord-018042-qt7055fw	33	7	in	in	IN
cord-018042-qt7055fw	33	8	which	which	WDT
cord-018042-qt7055fw	33	9	the	the	DT
cord-018042-qt7055fw	33	10	transgene	transgene	NN
cord-018042-qt7055fw	33	11	is	be	VBZ
cord-018042-qt7055fw	33	12	stably	stably	RB
cord-018042-qt7055fw	33	13	integrated	integrate	VBN
cord-018042-qt7055fw	33	14	into	into	IN
cord-018042-qt7055fw	33	15	the	the	DT
cord-018042-qt7055fw	33	16	genome	genome	NN
cord-018042-qt7055fw	33	17	can	can	MD
cord-018042-qt7055fw	33	18	be	be	VB
cord-018042-qt7055fw	33	19	developed	develop	VBN
cord-018042-qt7055fw	33	20	and	and	CC
cord-018042-qt7055fw	33	21	provide	provide	VB
cord-018042-qt7055fw	33	22	an	an	DT
cord-018042-qt7055fw	33	23	unrestricted	unrestricted	JJ
cord-018042-qt7055fw	33	24	source	source	NN
cord-018042-qt7055fw	33	25	of	of	IN
cord-018042-qt7055fw	33	26	animals	animal	NNS
cord-018042-qt7055fw	33	27	identical	identical	JJ
cord-018042-qt7055fw	33	28	for	for	IN
cord-018042-qt7055fw	33	29	the	the	DT
cord-018042-qt7055fw	33	30	introduced	introduce	VBN
cord-018042-qt7055fw	33	31	genetic	genetic	JJ
cord-018042-qt7055fw	33	32	and	and	CC
cord-018042-qt7055fw	33	33	molecular	molecular	JJ
cord-018042-qt7055fw	33	34	alteration	alteration	NN
cord-018042-qt7055fw	33	35	,	,	,
cord-018042-qt7055fw	33	36	hence	hence	RB
cord-018042-qt7055fw	33	37	permitting	permit	VBG
cord-018042-qt7055fw	33	38	systematic	systematic	JJ
cord-018042-qt7055fw	33	39	multi	multi	JJ
cord-018042-qt7055fw	33	40	-	-	JJ
cord-018042-qt7055fw	33	41	level	level	JJ
cord-018042-qt7055fw	33	42	analysis	analysis	NN
cord-018042-qt7055fw	33	43	of	of	IN
cord-018042-qt7055fw	33	44	pathological	pathological	JJ
cord-018042-qt7055fw	33	45	,	,	,
cord-018042-qt7055fw	33	46	electrophysiological	electrophysiological	JJ
cord-018042-qt7055fw	33	47	,	,	,
cord-018042-qt7055fw	33	48	neuroendocrinological	neuroendocrinological	JJ
cord-018042-qt7055fw	33	49	and	and	CC
cord-018042-qt7055fw	33	50	behavioral	behavioral	JJ
cord-018042-qt7055fw	33	51	manifestations	manifestation	NNS
cord-018042-qt7055fw	33	52	.	.	.
cord-018042-qt7055fw	34	1	For	for	IN
cord-018042-qt7055fw	34	2	more	more	RBR
cord-018042-qt7055fw	34	3	detailed	detailed	JJ
cord-018042-qt7055fw	34	4	reviews	review	NNS
cord-018042-qt7055fw	34	5	of	of	IN
cord-018042-qt7055fw	34	6	these	these	DT
cord-018042-qt7055fw	34	7	techniques	technique	NNS
cord-018042-qt7055fw	34	8	see	see	VB
cord-018042-qt7055fw	34	9	(	(	-LRB-
cord-018042-qt7055fw	34	10	Galli	Galli	NNP
cord-018042-qt7055fw	34	11	-	-	HYPH
cord-018042-qt7055fw	34	12	Taliadoros	Taliadoros	NNP
cord-018042-qt7055fw	34	13	et	et	NNP
cord-018042-qt7055fw	34	14	al	al	NNP
cord-018042-qt7055fw	34	15	.	.	NNP
cord-018042-qt7055fw	34	16	,	,	,
cord-018042-qt7055fw	34	17	1995	1995	CD
cord-018042-qt7055fw	34	18	;	;	:
cord-018042-qt7055fw	34	19	Campbell	Campbell	NNP
cord-018042-qt7055fw	34	20	and	and	CC
cord-018042-qt7055fw	34	21	Gold	Gold	NNP
cord-018042-qt7055fw	34	22	,	,	,
cord-018042-qt7055fw	34	23	1996	1996	CD
cord-018042-qt7055fw	34	24	;	;	:
cord-018042-qt7055fw	34	25	Campbell	Campbell	NNP
cord-018042-qt7055fw	34	26	et	et	NNP
cord-018042-qt7055fw	34	27	al	al	NNP
cord-018042-qt7055fw	34	28	.	.	NNP
cord-018042-qt7055fw	34	29	,	,	,
cord-018042-qt7055fw	34	30	1998	1998	CD
cord-018042-qt7055fw	34	31	)	)	-RRB-
cord-018042-qt7055fw	34	32	.	.	.
cord-018042-qt7055fw	35	1	The	the	DT
cord-018042-qt7055fw	35	2	application	application	NN
cord-018042-qt7055fw	35	3	of	of	IN
cord-018042-qt7055fw	35	4	genetically	genetically	RB
cord-018042-qt7055fw	35	5	-	-	HYPH
cord-018042-qt7055fw	35	6	manipulated	manipulate	VBN
cord-018042-qt7055fw	35	7	animal	animal	NN
cord-018042-qt7055fw	35	8	models	model	NNS
cord-018042-qt7055fw	35	9	to	to	TO
cord-018042-qt7055fw	35	10	study	study	VB
cord-018042-qt7055fw	35	11	the	the	DT
cord-018042-qt7055fw	35	12	CNS	CNS	NNP
cord-018042-qt7055fw	35	13	biology	biology	NN
cord-018042-qt7055fw	35	14	of	of	IN
cord-018042-qt7055fw	35	15	the	the	DT
cord-018042-qt7055fw	35	16	chemokines	chemokine	NNS
cord-018042-qt7055fw	35	17	and	and	CC
cord-018042-qt7055fw	35	18	their	-PRON-	PRP$
cord-018042-qt7055fw	35	19	receptors	receptor	NNS
cord-018042-qt7055fw	35	20	has	have	VBZ
cord-018042-qt7055fw	35	21	emerged	emerge	VBN
cord-018042-qt7055fw	35	22	as	as	IN
cord-018042-qt7055fw	35	23	an	an	DT
cord-018042-qt7055fw	35	24	important	important	JJ
cord-018042-qt7055fw	35	25	experimental	experimental	JJ
cord-018042-qt7055fw	35	26	approach	approach	NN
cord-018042-qt7055fw	35	27	.	.	.
cord-018042-qt7055fw	36	1	In	in	IN
cord-018042-qt7055fw	36	2	this	this	DT
cord-018042-qt7055fw	36	3	chapter	chapter	NN
cord-018042-qt7055fw	36	4	,	,	,
cord-018042-qt7055fw	36	5	we	-PRON-	PRP
cord-018042-qt7055fw	36	6	will	will	MD
cord-018042-qt7055fw	36	7	discuss	discuss	VB
cord-018042-qt7055fw	36	8	findings	finding	NNS
cord-018042-qt7055fw	36	9	from	from	IN
cord-018042-qt7055fw	36	10	studies	study	NNS
cord-018042-qt7055fw	36	11	based	base	VBN
cord-018042-qt7055fw	36	12	on	on	IN
cord-018042-qt7055fw	36	13	the	the	DT
cord-018042-qt7055fw	36	14	use	use	NN
cord-018042-qt7055fw	36	15	of	of	IN
cord-018042-qt7055fw	36	16	CNS	CNS	NNP
cord-018042-qt7055fw	36	17	-	-	HYPH
cord-018042-qt7055fw	36	18	chemokine	chemokine	NN
cord-018042-qt7055fw	36	19	transgenic	transgenic	JJ
cord-018042-qt7055fw	36	20	models	model	NNS
cord-018042-qt7055fw	36	21	.	.	.
cord-018042-qt7055fw	37	1	In	in	IN
cord-018042-qt7055fw	37	2	particular	particular	JJ
cord-018042-qt7055fw	37	3	,	,	,
cord-018042-qt7055fw	37	4	we	-PRON-	PRP
cord-018042-qt7055fw	37	5	will	will	MD
cord-018042-qt7055fw	37	6	focus	focus	VB
cord-018042-qt7055fw	37	7	on	on	IN
cord-018042-qt7055fw	37	8	the	the	DT
cord-018042-qt7055fw	37	9	contribution	contribution	NN
cord-018042-qt7055fw	37	10	that	that	IN
cord-018042-qt7055fw	37	11	these	these	DT
cord-018042-qt7055fw	37	12	models	model	NNS
cord-018042-qt7055fw	37	13	have	have	VBP
cord-018042-qt7055fw	37	14	made	make	VBN
cord-018042-qt7055fw	37	15	to	to	IN
cord-018042-qt7055fw	37	16	our	-PRON-	PRP$
cord-018042-qt7055fw	37	17	understanding	understanding	NN
cord-018042-qt7055fw	37	18	of	of	IN
cord-018042-qt7055fw	37	19	the	the	DT
cord-018042-qt7055fw	37	20	basic	basic	JJ
cord-018042-qt7055fw	37	21	functions	function	NNS
cord-018042-qt7055fw	37	22	and	and	CC
cord-018042-qt7055fw	37	23	mechanisms	mechanism	NNS
cord-018042-qt7055fw	37	24	of	of	IN
cord-018042-qt7055fw	37	25	actions	action	NNS
cord-018042-qt7055fw	37	26	of	of	IN
cord-018042-qt7055fw	37	27	chemokines	chemokine	NNS
cord-018042-qt7055fw	37	28	in	in	IN
cord-018042-qt7055fw	37	29	the	the	DT
cord-018042-qt7055fw	37	30	CNS	CNS	NNP
cord-018042-qt7055fw	37	31	.	.	.
cord-018042-qt7055fw	38	1	As	as	IN
cord-018042-qt7055fw	38	2	mentioned	mention	VBN
cord-018042-qt7055fw	38	3	in	in	IN
cord-018042-qt7055fw	38	4	the	the	DT
cord-018042-qt7055fw	38	5	preceding	preceding	NN
cord-018042-qt7055fw	38	6	,	,	,
cord-018042-qt7055fw	38	7	a	a	DT
cord-018042-qt7055fw	38	8	great	great	JJ
cord-018042-qt7055fw	38	9	many	many	JJ
cord-018042-qt7055fw	38	10	chemokines	chemokine	NNS
cord-018042-qt7055fw	38	11	belonging	belong	VBG
cord-018042-qt7055fw	38	12	in	in	IN
cord-018042-qt7055fw	38	13	particular	particular	JJ
cord-018042-qt7055fw	38	14	to	to	IN
cord-018042-qt7055fw	38	15	the	the	DT
cord-018042-qt7055fw	38	16	CXC	CXC	NNP
cord-018042-qt7055fw	38	17	and	and	CC
cord-018042-qt7055fw	38	18	CC	CC	NNP
cord-018042-qt7055fw	38	19	families	family	NNS
cord-018042-qt7055fw	38	20	are	be	VBP
cord-018042-qt7055fw	38	21	known	know	VBN
cord-018042-qt7055fw	38	22	to	to	TO
cord-018042-qt7055fw	38	23	be	be	VB
cord-018042-qt7055fw	38	24	induced	induce	VBN
cord-018042-qt7055fw	38	25	in	in	IN
cord-018042-qt7055fw	38	26	the	the	DT
cord-018042-qt7055fw	38	27	brain	brain	NN
cord-018042-qt7055fw	38	28	during	during	IN
cord-018042-qt7055fw	38	29	a	a	DT
cord-018042-qt7055fw	38	30	variety	variety	NN
cord-018042-qt7055fw	38	31	of	of	IN
cord-018042-qt7055fw	38	32	different	different	JJ
cord-018042-qt7055fw	38	33	pathologic	pathologic	JJ
cord-018042-qt7055fw	38	34	states	state	NNS
cord-018042-qt7055fw	38	35	(	(	-LRB-
cord-018042-qt7055fw	38	36	Asensio	Asensio	NNP
cord-018042-qt7055fw	38	37	and	and	CC
cord-018042-qt7055fw	38	38	Campbell	Campbell	NNP
cord-018042-qt7055fw	38	39	,	,	,
cord-018042-qt7055fw	38	40	1999	1999	CD
cord-018042-qt7055fw	38	41	;	;	:
cord-018042-qt7055fw	38	42	Ransohoff	Ransohoff	NNP
cord-018042-qt7055fw	38	43	,	,	,
cord-018042-qt7055fw	38	44	2002	2002	CD
cord-018042-qt7055fw	39	1	;	;	:
cord-018042-qt7055fw	39	2	Rebenko	Rebenko	NNP
cord-018042-qt7055fw	39	3	-	-	HYPH
cord-018042-qt7055fw	39	4	Moll	Moll	NNP
cord-018042-qt7055fw	39	5	et	et	FW
cord-018042-qt7055fw	39	6	al	al	NNP
cord-018042-qt7055fw	39	7	.	.	NNP
cord-018042-qt7055fw	39	8	,	,	,
cord-018042-qt7055fw	39	9	2006	2006	CD
cord-018042-qt7055fw	39	10	;	;	.
cord-018042-qt7055fw	40	1	Ubogu	Ubogu	NNP
cord-018042-qt7055fw	40	2	et	et	NNP
cord-018042-qt7055fw	40	3	al	al	NNP
cord-018042-qt7055fw	40	4	.	.	NNP
cord-018042-qt7055fw	40	5	,	,	,
cord-018042-qt7055fw	40	6	2006	2006	CD
cord-018042-qt7055fw	40	7	)	)	-RRB-
cord-018042-qt7055fw	40	8	.	.	.
cord-018042-qt7055fw	41	1	The	the	DT
cord-018042-qt7055fw	41	2	consequences	consequence	NNS
cord-018042-qt7055fw	41	3	of	of	IN
cord-018042-qt7055fw	41	4	chemokine	chemokine	JJ
cord-018042-qt7055fw	41	5	expression	expression	NN
cord-018042-qt7055fw	41	6	in	in	IN
cord-018042-qt7055fw	41	7	the	the	DT
cord-018042-qt7055fw	41	8	unmanipulated	unmanipulated	JJ
cord-018042-qt7055fw	41	9	CNS	CNS	NNP
cord-018042-qt7055fw	41	10	and	and	CC
cord-018042-qt7055fw	41	11	in	in	IN
cord-018042-qt7055fw	41	12	some	some	DT
cord-018042-qt7055fw	41	13	cases	case	NNS
cord-018042-qt7055fw	41	14	in	in	IN
cord-018042-qt7055fw	41	15	stimulus	stimulus	NN
cord-018042-qt7055fw	41	16	-	-	HYPH
cord-018042-qt7055fw	41	17	evoked	evoke	VBN
cord-018042-qt7055fw	41	18	disease	disease	NN
cord-018042-qt7055fw	41	19	models	model	NNS
cord-018042-qt7055fw	41	20	have	have	VBP
cord-018042-qt7055fw	41	21	been	be	VBN
cord-018042-qt7055fw	41	22	examined	examine	VBN
cord-018042-qt7055fw	41	23	in	in	IN
cord-018042-qt7055fw	41	24	transgenic	transgenic	JJ
cord-018042-qt7055fw	41	25	mice	mouse	NNS
cord-018042-qt7055fw	41	26	with	with	IN
cord-018042-qt7055fw	41	27	CNS	CNS	NNP
cord-018042-qt7055fw	41	28	-	-	HYPH
cord-018042-qt7055fw	41	29	targeted	target	VBN
cord-018042-qt7055fw	41	30	expression	expression	NN
cord-018042-qt7055fw	41	31	of	of	IN
cord-018042-qt7055fw	41	32	specific	specific	JJ
cord-018042-qt7055fw	41	33	chemokines	chemokine	NNS
cord-018042-qt7055fw	41	34	.	.	.
cord-018042-qt7055fw	42	1	A	a	DT
cord-018042-qt7055fw	42	2	summary	summary	NN
cord-018042-qt7055fw	42	3	of	of	IN
cord-018042-qt7055fw	42	4	the	the	DT
cord-018042-qt7055fw	42	5	salient	salient	JJ
cord-018042-qt7055fw	42	6	features	feature	NNS
cord-018042-qt7055fw	42	7	of	of	IN
cord-018042-qt7055fw	42	8	transgenic	transgenic	JJ
cord-018042-qt7055fw	42	9	models	model	NNS
cord-018042-qt7055fw	42	10	in	in	IN
cord-018042-qt7055fw	42	11	which	which	WDT
cord-018042-qt7055fw	42	12	CNS	CNS	NNP
cord-018042-qt7055fw	42	13	-	-	HYPH
cord-018042-qt7055fw	42	14	specific	specific	JJ
cord-018042-qt7055fw	42	15	promoter	promoter	NN
cord-018042-qt7055fw	42	16	constructs	construct	NNS
cord-018042-qt7055fw	42	17	were	be	VBD
cord-018042-qt7055fw	42	18	used	use	VBN
cord-018042-qt7055fw	42	19	to	to	TO
cord-018042-qt7055fw	42	20	drive	drive	VB
cord-018042-qt7055fw	42	21	expression	expression	NN
cord-018042-qt7055fw	42	22	of	of	IN
cord-018042-qt7055fw	42	23	a	a	DT
cord-018042-qt7055fw	42	24	specific	specific	JJ
cord-018042-qt7055fw	42	25	chemokine	chemokine	NN
cord-018042-qt7055fw	42	26	gene	gene	NN
cord-018042-qt7055fw	42	27	is	be	VBZ
cord-018042-qt7055fw	42	28	given	give	VBN
cord-018042-qt7055fw	42	29	in	in	IN
cord-018042-qt7055fw	42	30	Table	Table	NNP
cord-018042-qt7055fw	42	31	1	1	CD
cord-018042-qt7055fw	42	32	and	and	CC
cord-018042-qt7055fw	42	33	will	will	MD
cord-018042-qt7055fw	42	34	be	be	VB
cord-018042-qt7055fw	42	35	outlined	outline	VBN
cord-018042-qt7055fw	42	36	in	in	IN
cord-018042-qt7055fw	42	37	more	more	JJR
cord-018042-qt7055fw	42	38	detail	detail	NN
cord-018042-qt7055fw	42	39	in	in	IN
cord-018042-qt7055fw	42	40	the	the	DT
cord-018042-qt7055fw	42	41	following	follow	VBG
cord-018042-qt7055fw	42	42	commentary	commentary	NN
cord-018042-qt7055fw	42	43	.	.	.
cord-018042-qt7055fw	43	1	The	the	DT
cord-018042-qt7055fw	43	2	chemokine	chemokine	NN
cord-018042-qt7055fw	43	3	CXCL1	cxcl1	NN
cord-018042-qt7055fw	43	4	(	(	-LRB-
cord-018042-qt7055fw	43	5	also	also	RB
cord-018042-qt7055fw	43	6	known	know	VBN
cord-018042-qt7055fw	43	7	as	as	IN
cord-018042-qt7055fw	43	8	GRO	GRO	NNP
cord-018042-qt7055fw	43	9	-	-	HYPH
cord-018042-qt7055fw	43	10	α	α	NNP
cord-018042-qt7055fw	43	11	/	/	SYM
cord-018042-qt7055fw	43	12	KC	KC	NNP
cord-018042-qt7055fw	43	13	/	/	SYM
cord-018042-qt7055fw	43	14	N51	N51	NNP
cord-018042-qt7055fw	43	15	)	)	-RRB-
cord-018042-qt7055fw	43	16	contains	contain	VBZ
cord-018042-qt7055fw	43	17	an	an	DT
cord-018042-qt7055fw	43	18	N	n	CD
cord-018042-qt7055fw	43	19	-	-	HYPH
cord-018042-qt7055fw	43	20	terminal	terminal	NN
cord-018042-qt7055fw	43	21	ELR	ELR	NNP
cord-018042-qt7055fw	43	22	-	-	HYPH
cord-018042-qt7055fw	43	23	amino	amino	NN
cord-018042-qt7055fw	43	24	acid	acid	NN
cord-018042-qt7055fw	43	25	motif	motif	NN
cord-018042-qt7055fw	43	26	and	and	CC
cord-018042-qt7055fw	43	27	belongs	belong	VBZ
cord-018042-qt7055fw	43	28	to	to	IN
cord-018042-qt7055fw	43	29	the	the	DT
cord-018042-qt7055fw	43	30	CXC	CXC	NNP
cord-018042-qt7055fw	43	31	-	-	HYPH
cord-018042-qt7055fw	43	32	chemokine	chemokine	NN
cord-018042-qt7055fw	43	33	family	family	NN
cord-018042-qt7055fw	43	34	.	.	.
cord-018042-qt7055fw	44	1	CXCL1	CXCL1	NNP
cord-018042-qt7055fw	44	2	binds	bind	VBZ
cord-018042-qt7055fw	44	3	to	to	IN
cord-018042-qt7055fw	44	4	the	the	DT
cord-018042-qt7055fw	44	5	CXCR2	CXCR2	NNP
cord-018042-qt7055fw	44	6	receptor	receptor	NN
cord-018042-qt7055fw	44	7	found	find	VBD
cord-018042-qt7055fw	44	8	predominantly	predominantly	RB
cord-018042-qt7055fw	44	9	on	on	IN
cord-018042-qt7055fw	44	10	the	the	DT
cord-018042-qt7055fw	44	11	surface	surface	NN
cord-018042-qt7055fw	44	12	of	of	IN
cord-018042-qt7055fw	44	13	neutrophils	neutrophil	NNS
cord-018042-qt7055fw	44	14	.	.	.
cord-018042-qt7055fw	45	1	Not	not	RB
cord-018042-qt7055fw	45	2	surprisingly	surprisingly	RB
cord-018042-qt7055fw	45	3	,	,	,
cord-018042-qt7055fw	45	4	CXCL1	CXCL1	NNP
cord-018042-qt7055fw	45	5	is	be	VBZ
cord-018042-qt7055fw	45	6	a	a	DT
cord-018042-qt7055fw	45	7	potent	potent	JJ
cord-018042-qt7055fw	45	8	neutrophil	neutrophil	NN
cord-018042-qt7055fw	45	9	chemoattractant	chemoattractant	NN
cord-018042-qt7055fw	45	10	.	.	.
cord-018042-qt7055fw	46	1	That	that	IN
cord-018042-qt7055fw	46	2	this	this	DT
cord-018042-qt7055fw	46	3	chemokine	chemokine	NN
cord-018042-qt7055fw	46	4	has	have	VBZ
cord-018042-qt7055fw	46	5	a	a	DT
cord-018042-qt7055fw	46	6	wider	wide	JJR
cord-018042-qt7055fw	46	7	function	function	NN
cord-018042-qt7055fw	46	8	in	in	IN
cord-018042-qt7055fw	46	9	the	the	DT
cord-018042-qt7055fw	46	10	CNS	CNS	NNP
cord-018042-qt7055fw	46	11	is	be	VBZ
cord-018042-qt7055fw	46	12	supported	support	VBN
cord-018042-qt7055fw	46	13	by	by	IN
cord-018042-qt7055fw	46	14	numerous	numerous	JJ
cord-018042-qt7055fw	46	15	studies	study	NNS
cord-018042-qt7055fw	46	16	.	.	.
cord-018042-qt7055fw	47	1	Cells	cell	NNS
cord-018042-qt7055fw	47	2	intrinsic	intrinsic	JJ
cord-018042-qt7055fw	47	3	to	to	IN
cord-018042-qt7055fw	47	4	the	the	DT
cord-018042-qt7055fw	47	5	CNS	CNS	NNP
cord-018042-qt7055fw	47	6	including	include	VBG
cord-018042-qt7055fw	47	7	neurons	neuron	NNS
cord-018042-qt7055fw	47	8	(	(	-LRB-
cord-018042-qt7055fw	47	9	Horuk	Horuk	NNP
cord-018042-qt7055fw	47	10	et	et	NNP
cord-018042-qt7055fw	47	11	al	al	NNP
cord-018042-qt7055fw	47	12	.	.	NNP
cord-018042-qt7055fw	47	13	,	,	,
cord-018042-qt7055fw	47	14	1997	1997	CD
cord-018042-qt7055fw	47	15	)	)	-RRB-
cord-018042-qt7055fw	47	16	,	,	,
cord-018042-qt7055fw	47	17	astrocytes	astrocyte	NNS
cord-018042-qt7055fw	47	18	(	(	-LRB-
cord-018042-qt7055fw	48	1	Danik	Danik	NNP
cord-018042-qt7055fw	48	2	et	et	FW
cord-018042-qt7055fw	48	3	al	al	NNP
cord-018042-qt7055fw	48	4	.	.	NNP
cord-018042-qt7055fw	48	5	,	,	,
cord-018042-qt7055fw	48	6	2003	2003	CD
cord-018042-qt7055fw	48	7	;	;	:
cord-018042-qt7055fw	49	1	Flynn	Flynn	NNP
cord-018042-qt7055fw	49	2	et	et	NNP
cord-018042-qt7055fw	49	3	al	al	NNP
cord-018042-qt7055fw	49	4	.	.	.
cord-018042-qt7055fw	50	1	,	,	,
cord-018042-qt7055fw	50	2	2003	2003	CD
cord-018042-qt7055fw	50	3	)	)	-RRB-
cord-018042-qt7055fw	50	4	,	,	,
cord-018042-qt7055fw	50	5	microglia	microglia	NNP
cord-018042-qt7055fw	50	6	(	(	-LRB-
cord-018042-qt7055fw	50	7	Filipovic	Filipovic	NNP
cord-018042-qt7055fw	50	8	et	et	FW
cord-018042-qt7055fw	50	9	al	al	NNP
cord-018042-qt7055fw	50	10	.	.	.
cord-018042-qt7055fw	51	1	,	,	,
cord-018042-qt7055fw	51	2	2003	2003	CD
cord-018042-qt7055fw	51	3	;	;	:
cord-018042-qt7055fw	51	4	Flynn	Flynn	NNP
cord-018042-qt7055fw	51	5	et	et	NNP
cord-018042-qt7055fw	51	6	al	al	NNP
cord-018042-qt7055fw	51	7	.	.	.
cord-018042-qt7055fw	52	1	,	,	,
cord-018042-qt7055fw	52	2	2003	2003	CD
cord-018042-qt7055fw	52	3	)	)	-RRB-
cord-018042-qt7055fw	52	4	,	,	,
cord-018042-qt7055fw	52	5	oligodendrocyte	oligodendrocyte	NNP
cord-018042-qt7055fw	52	6	precursor	precursor	NN
cord-018042-qt7055fw	52	7	cells	cell	NNS
cord-018042-qt7055fw	52	8	(	(	-LRB-
cord-018042-qt7055fw	52	9	Nguyen	Nguyen	NNP
cord-018042-qt7055fw	52	10	and	and	CC
cord-018042-qt7055fw	52	11	Stangel	Stangel	NNP
cord-018042-qt7055fw	52	12	,	,	,
cord-018042-qt7055fw	52	13	2001	2001	CD
cord-018042-qt7055fw	52	14	)	)	-RRB-
cord-018042-qt7055fw	52	15	and	and	CC
cord-018042-qt7055fw	52	16	mature	mature	VB
cord-018042-qt7055fw	52	17	oligodendrocytes	oligodendrocyte	NNS
cord-018042-qt7055fw	52	18	(	(	-LRB-
cord-018042-qt7055fw	52	19	Omari	Omari	NNP
cord-018042-qt7055fw	52	20	et	et	NNP
cord-018042-qt7055fw	52	21	al	al	NNP
cord-018042-qt7055fw	52	22	.	.	NNP
cord-018042-qt7055fw	52	23	,	,	,
cord-018042-qt7055fw	52	24	2006	2006	CD
cord-018042-qt7055fw	52	25	)	)	-RRB-
cord-018042-qt7055fw	52	26	have	have	VBP
cord-018042-qt7055fw	52	27	been	be	VBN
cord-018042-qt7055fw	52	28	reported	report	VBN
cord-018042-qt7055fw	52	29	to	to	TO
cord-018042-qt7055fw	52	30	have	have	VB
cord-018042-qt7055fw	52	31	the	the	DT
cord-018042-qt7055fw	52	32	CXCR2	CXCR2	NNP
cord-018042-qt7055fw	52	33	receptor	receptor	NN
cord-018042-qt7055fw	52	34	.	.	.
cord-018042-qt7055fw	53	1	A	a	DT
cord-018042-qt7055fw	53	2	role	role	NN
cord-018042-qt7055fw	53	3	for	for	IN
cord-018042-qt7055fw	53	4	CXCR2/	CXCR2/	NNP
cord-018042-qt7055fw	53	5	CXCL1	CXCL1	NNP
cord-018042-qt7055fw	53	6	interaction	interaction	NN
cord-018042-qt7055fw	53	7	is	be	VBZ
cord-018042-qt7055fw	53	8	documented	document	VBN
cord-018042-qt7055fw	53	9	in	in	IN
cord-018042-qt7055fw	53	10	rodents	rodent	NNS
cord-018042-qt7055fw	53	11	in	in	IN
cord-018042-qt7055fw	53	12	the	the	DT
cord-018042-qt7055fw	53	13	development	development	NN
cord-018042-qt7055fw	53	14	and	and	CC
cord-018042-qt7055fw	53	15	maintenance	maintenance	NN
cord-018042-qt7055fw	53	16	of	of	IN
cord-018042-qt7055fw	53	17	the	the	DT
cord-018042-qt7055fw	53	18	oligodendrocyte	oligodendrocyte	NNP
cord-018042-qt7055fw	53	19	lineage	lineage	NN
cord-018042-qt7055fw	53	20	,	,	,
cord-018042-qt7055fw	53	21	myelination	myelination	NN
cord-018042-qt7055fw	53	22	,	,	,
cord-018042-qt7055fw	53	23	and	and	CC
cord-018042-qt7055fw	53	24	white	white	JJ
cord-018042-qt7055fw	53	25	matter	matter	NN
cord-018042-qt7055fw	53	26	in	in	IN
cord-018042-qt7055fw	53	27	the	the	DT
cord-018042-qt7055fw	53	28	neonatal	neonatal	JJ
cord-018042-qt7055fw	53	29	and	and	CC
cord-018042-qt7055fw	53	30	adult	adult	NN
cord-018042-qt7055fw	53	31	CNS	CNS	NNP
cord-018042-qt7055fw	54	1	(	(	-LRB-
cord-018042-qt7055fw	54	2	Padovani	Padovani	NNP
cord-018042-qt7055fw	54	3	-	-	HYPH
cord-018042-qt7055fw	54	4	Claudio	Claudio	NNP
cord-018042-qt7055fw	54	5	et	et	NNP
cord-018042-qt7055fw	54	6	al	al	NNP
cord-018042-qt7055fw	54	7	.	.	NNP
cord-018042-qt7055fw	54	8	,	,	,
cord-018042-qt7055fw	54	9	2006	2006	CD
cord-018042-qt7055fw	54	10	)	)	-RRB-
cord-018042-qt7055fw	54	11	.	.	.
cord-018042-qt7055fw	55	1	The	the	DT
cord-018042-qt7055fw	55	2	CNS	CNS	NNP
cord-018042-qt7055fw	55	3	function	function	NN
cord-018042-qt7055fw	55	4	of	of	IN
cord-018042-qt7055fw	55	5	this	this	DT
cord-018042-qt7055fw	55	6	chemokine	chemokine	NN
cord-018042-qt7055fw	55	7	was	be	VBD
cord-018042-qt7055fw	55	8	examined	examine	VBN
cord-018042-qt7055fw	55	9	in	in	IN
cord-018042-qt7055fw	55	10	transgenic	transgenic	JJ
cord-018042-qt7055fw	55	11	mice	mouse	NNS
cord-018042-qt7055fw	55	12	by	by	IN
cord-018042-qt7055fw	55	13	placing	place	VBG
cord-018042-qt7055fw	55	14	the	the	DT
cord-018042-qt7055fw	55	15	CXCL1	CXCL1	NNP
cord-018042-qt7055fw	55	16	gene	gene	NN
cord-018042-qt7055fw	55	17	under	under	IN
cord-018042-qt7055fw	55	18	the	the	DT
cord-018042-qt7055fw	55	19	transcriptional	transcriptional	JJ
cord-018042-qt7055fw	55	20	control	control	NN
cord-018042-qt7055fw	55	21	of	of	IN
cord-018042-qt7055fw	55	22	the	the	DT
cord-018042-qt7055fw	55	23	myelin	myelin	JJ
cord-018042-qt7055fw	55	24	basic	basic	JJ
cord-018042-qt7055fw	55	25	protein	protein	NN
cord-018042-qt7055fw	55	26	(	(	-LRB-
cord-018042-qt7055fw	55	27	MBP	MBP	NNP
cord-018042-qt7055fw	55	28	)	)	-RRB-
cord-018042-qt7055fw	55	29	promoter	promoter	NN
cord-018042-qt7055fw	55	30	.	.	.
cord-018042-qt7055fw	56	1	In	in	IN
cord-018042-qt7055fw	56	2	the	the	DT
cord-018042-qt7055fw	56	3	resulting	result	VBG
cord-018042-qt7055fw	56	4	transgenic	transgenic	JJ
cord-018042-qt7055fw	56	5	mice	mouse	NNS
cord-018042-qt7055fw	56	6	(	(	-LRB-
cord-018042-qt7055fw	56	7	termed	term	VBN
cord-018042-qt7055fw	56	8	MBP	MBP	NNP
cord-018042-qt7055fw	56	9	-	-	HYPH
cord-018042-qt7055fw	56	10	KC	KC	NNP
cord-018042-qt7055fw	56	11	)	)	-RRB-
cord-018042-qt7055fw	56	12	transgene	transgene	NN
cord-018042-qt7055fw	56	13	-	-	HYPH
cord-018042-qt7055fw	56	14	encoded	encode	VBN
cord-018042-qt7055fw	56	15	mRNA	mrna	NN
cord-018042-qt7055fw	56	16	levels	level	NNS
cord-018042-qt7055fw	56	17	were	be	VBD
cord-018042-qt7055fw	56	18	coincident	coincident	JJ
cord-018042-qt7055fw	56	19	with	with	IN
cord-018042-qt7055fw	56	20	the	the	DT
cord-018042-qt7055fw	56	21	developmentallyregulated	developmentallyregulated	JJ
cord-018042-qt7055fw	56	22	pattern	pattern	NN
cord-018042-qt7055fw	56	23	of	of	IN
cord-018042-qt7055fw	56	24	endogenous	endogenous	JJ
cord-018042-qt7055fw	56	25	MBP	MBP	NNP
cord-018042-qt7055fw	56	26	,	,	,
cord-018042-qt7055fw	56	27	peaking	peak	VBG
cord-018042-qt7055fw	56	28	at	at	IN
cord-018042-qt7055fw	56	29	2	2	CD
cord-018042-qt7055fw	56	30	-	-	SYM
cord-018042-qt7055fw	56	31	3	3	CD
cord-018042-qt7055fw	56	32	week	week	NN
cord-018042-qt7055fw	56	33	of	of	IN
cord-018042-qt7055fw	56	34	age	age	NN
cord-018042-qt7055fw	56	35	,	,	,
cord-018042-qt7055fw	56	36	before	before	IN
cord-018042-qt7055fw	56	37	declining	decline	VBG
cord-018042-qt7055fw	56	38	to	to	IN
cord-018042-qt7055fw	56	39	low	low	JJ
cord-018042-qt7055fw	56	40	levels	level	NNS
cord-018042-qt7055fw	56	41	characteristically	characteristically	RB
cord-018042-qt7055fw	56	42	seen	see	VBN
cord-018042-qt7055fw	56	43	in	in	IN
cord-018042-qt7055fw	56	44	adult	adult	NN
cord-018042-qt7055fw	56	45	brain	brain	NN
cord-018042-qt7055fw	56	46	.	.	.
cord-018042-qt7055fw	57	1	During	during	IN
cord-018042-qt7055fw	57	2	the	the	DT
cord-018042-qt7055fw	57	3	period	period	NN
cord-018042-qt7055fw	57	4	of	of	IN
cord-018042-qt7055fw	57	5	maximal	maximal	JJ
cord-018042-qt7055fw	57	6	transgene	transgene	NN
cord-018042-qt7055fw	57	7	expression	expression	NN
cord-018042-qt7055fw	57	8	,	,	,
cord-018042-qt7055fw	57	9	the	the	DT
cord-018042-qt7055fw	57	10	brain	brain	NN
cord-018042-qt7055fw	57	11	of	of	IN
cord-018042-qt7055fw	57	12	MBP	MBP	NNP
cord-018042-qt7055fw	57	13	-	-	HYPH
cord-018042-qt7055fw	57	14	KC	KC	NNP
cord-018042-qt7055fw	57	15	mice	mouse	NNS
cord-018042-qt7055fw	57	16	was	be	VBD
cord-018042-qt7055fw	57	17	heavily	heavily	RB
cord-018042-qt7055fw	57	18	infiltrated	infiltrate	VBN
cord-018042-qt7055fw	57	19	with	with	IN
cord-018042-qt7055fw	57	20	neutrophils	neutrophil	NNS
cord-018042-qt7055fw	57	21	that	that	WDT
cord-018042-qt7055fw	57	22	accumulated	accumulate	VBN
cord-018042-qt7055fw	57	23	in	in	IN
cord-018042-qt7055fw	57	24	perivascular	perivascular	JJ
cord-018042-qt7055fw	57	25	,	,	,
cord-018042-qt7055fw	57	26	meningeal	meningeal	JJ
cord-018042-qt7055fw	57	27	and	and	CC
cord-018042-qt7055fw	57	28	parenchymal	parenchymal	JJ
cord-018042-qt7055fw	57	29	sites	site	NNS
cord-018042-qt7055fw	57	30	.	.	.
cord-018042-qt7055fw	58	1	At	at	IN
cord-018042-qt7055fw	58	2	this	this	DT
cord-018042-qt7055fw	58	3	time	time	NN
cord-018042-qt7055fw	58	4	,	,	,
cord-018042-qt7055fw	58	5	despite	despite	IN
cord-018042-qt7055fw	58	6	loss	loss	NN
cord-018042-qt7055fw	58	7	of	of	IN
cord-018042-qt7055fw	58	8	blood	blood	NN
cord-018042-qt7055fw	58	9	brain	brain	NN
cord-018042-qt7055fw	58	10	barrier	barrier	NN
cord-018042-qt7055fw	58	11	(	(	-LRB-
cord-018042-qt7055fw	58	12	BBB	BBB	NNP
cord-018042-qt7055fw	58	13	)	)	-RRB-
cord-018042-qt7055fw	58	14	integrity	integrity	NN
cord-018042-qt7055fw	58	15	and	and	CC
cord-018042-qt7055fw	58	16	focal	focal	JJ
cord-018042-qt7055fw	58	17	gliosis	gliosis	NN
cord-018042-qt7055fw	58	18	,	,	,
cord-018042-qt7055fw	58	19	there	there	EX
cord-018042-qt7055fw	58	20	was	be	VBD
cord-018042-qt7055fw	58	21	no	no	DT
cord-018042-qt7055fw	58	22	evidence	evidence	NN
cord-018042-qt7055fw	58	23	of	of	IN
cord-018042-qt7055fw	58	24	brain	brain	NN
cord-018042-qt7055fw	58	25	tissue	tissue	NN
cord-018042-qt7055fw	58	26	destruction	destruction	NN
cord-018042-qt7055fw	58	27	nor	nor	CC
cord-018042-qt7055fw	58	28	did	do	VBD
cord-018042-qt7055fw	58	29	affected	affect	VBN
cord-018042-qt7055fw	58	30	animals	animal	NNS
cord-018042-qt7055fw	58	31	display	display	VBP
cord-018042-qt7055fw	58	32	abnormal	abnormal	JJ
cord-018042-qt7055fw	58	33	neurological	neurological	JJ
cord-018042-qt7055fw	58	34	signs	sign	NNS
cord-018042-qt7055fw	58	35	.	.	.
cord-018042-qt7055fw	59	1	These	these	DT
cord-018042-qt7055fw	59	2	results	result	NNS
cord-018042-qt7055fw	59	3	underscore	underscore	VBP
cord-018042-qt7055fw	59	4	the	the	DT
cord-018042-qt7055fw	59	5	ability	ability	NN
cord-018042-qt7055fw	59	6	of	of	IN
cord-018042-qt7055fw	59	7	CXCL1	cxcl1	NN
cord-018042-qt7055fw	59	8	to	to	TO
cord-018042-qt7055fw	59	9	promote	promote	VB
cord-018042-qt7055fw	59	10	neutrophil	neutrophil	NN
cord-018042-qt7055fw	59	11	migration	migration	NN
cord-018042-qt7055fw	59	12	to	to	IN
cord-018042-qt7055fw	59	13	and	and	CC
cord-018042-qt7055fw	59	14	extravasation	extravasation	NN
cord-018042-qt7055fw	59	15	in	in	IN
cord-018042-qt7055fw	59	16	the	the	DT
cord-018042-qt7055fw	59	17	CNS	CNS	NNP
cord-018042-qt7055fw	59	18	.	.	.
cord-018042-qt7055fw	60	1	However	however	RB
cord-018042-qt7055fw	60	2	,	,	,
cord-018042-qt7055fw	60	3	the	the	DT
cord-018042-qt7055fw	60	4	absence	absence	NN
cord-018042-qt7055fw	60	5	of	of	IN
cord-018042-qt7055fw	60	6	any	any	DT
cord-018042-qt7055fw	60	7	tissue	tissue	NN
cord-018042-qt7055fw	60	8	destruction	destruction	NN
cord-018042-qt7055fw	60	9	suggests	suggest	VBZ
cord-018042-qt7055fw	60	10	that	that	IN
cord-018042-qt7055fw	60	11	this	this	DT
cord-018042-qt7055fw	60	12	chemokine	chemokine	NN
cord-018042-qt7055fw	60	13	does	do	VBZ
cord-018042-qt7055fw	60	14	not	not	RB
cord-018042-qt7055fw	60	15	activate	activate	VB
cord-018042-qt7055fw	60	16	the	the	DT
cord-018042-qt7055fw	60	17	neutrophils	neutrophil	NNS
cord-018042-qt7055fw	60	18	.	.	.
cord-018042-qt7055fw	61	1	Curiously	curiously	RB
cord-018042-qt7055fw	61	2	,	,	,
cord-018042-qt7055fw	61	3	in	in	IN
cord-018042-qt7055fw	61	4	one	one	CD
cord-018042-qt7055fw	61	5	high	high	JJ
cord-018042-qt7055fw	61	6	transgene	transgene	NN
cord-018042-qt7055fw	61	7	expressing	express	VBG
cord-018042-qt7055fw	61	8	line	line	NN
cord-018042-qt7055fw	61	9	,	,	,
cord-018042-qt7055fw	61	10	from	from	IN
cord-018042-qt7055fw	61	11	>	>	XX
cord-018042-qt7055fw	61	12	40	40	CD
cord-018042-qt7055fw	61	13	days	day	NNS
cord-018042-qt7055fw	61	14	of	of	IN
cord-018042-qt7055fw	61	15	age	age	NN
cord-018042-qt7055fw	61	16	,	,	,
cord-018042-qt7055fw	61	17	mice	mouse	NNS
cord-018042-qt7055fw	61	18	exhibited	exhibit	VBD
cord-018042-qt7055fw	61	19	a	a	DT
cord-018042-qt7055fw	61	20	syndrome	syndrome	NN
cord-018042-qt7055fw	61	21	of	of	IN
cord-018042-qt7055fw	61	22	progressive	progressive	JJ
cord-018042-qt7055fw	61	23	neurological	neurological	JJ
cord-018042-qt7055fw	61	24	dysfunction	dysfunction	NN
cord-018042-qt7055fw	61	25	consisting	consist	VBG
cord-018042-qt7055fw	61	26	of	of	IN
cord-018042-qt7055fw	61	27	slowing	slow	VBG
cord-018042-qt7055fw	61	28	(	(	-LRB-
cord-018042-qt7055fw	61	29	Boztug	Boztug	NNP
cord-018042-qt7055fw	61	30	et	et	NNP
cord-018042-qt7055fw	61	31	al	al	NNP
cord-018042-qt7055fw	61	32	.	.	NNP
cord-018042-qt7055fw	61	33	,	,	,
cord-018042-qt7055fw	61	34	2002	2002	CD
cord-018042-qt7055fw	61	35	)	)	-RRB-
cord-018042-qt7055fw	61	36	of	of	IN
cord-018042-qt7055fw	61	37	the	the	DT
cord-018042-qt7055fw	61	38	righting	right	VBG
cord-018042-qt7055fw	61	39	reflex	reflex	NN
cord-018042-qt7055fw	61	40	,	,	,
cord-018042-qt7055fw	61	41	clumsiness	clumsiness	NN
cord-018042-qt7055fw	61	42	,	,	,
cord-018042-qt7055fw	61	43	increase	increase	NN
cord-018042-qt7055fw	61	44	of	of	IN
cord-018042-qt7055fw	61	45	rigidity	rigidity	NN
cord-018042-qt7055fw	61	46	of	of	IN
cord-018042-qt7055fw	61	47	the	the	DT
cord-018042-qt7055fw	61	48	hindlimbs	hindlimb	NNS
cord-018042-qt7055fw	61	49	and	and	CC
cord-018042-qt7055fw	61	50	tail	tail	NN
cord-018042-qt7055fw	61	51	and	and	CC
cord-018042-qt7055fw	61	52	profound	profound	JJ
cord-018042-qt7055fw	61	53	truncal	truncal	NN
cord-018042-qt7055fw	61	54	instability	instability	NN
cord-018042-qt7055fw	61	55	.	.	.
cord-018042-qt7055fw	62	1	The	the	DT
cord-018042-qt7055fw	62	2	major	major	JJ
cord-018042-qt7055fw	62	3	neuropathological	neuropathological	JJ
cord-018042-qt7055fw	62	4	findings	finding	NNS
cord-018042-qt7055fw	62	5	were	be	VBD
cord-018042-qt7055fw	62	6	florid	florid	JJ
cord-018042-qt7055fw	62	7	microglial	microglial	JJ
cord-018042-qt7055fw	62	8	activation	activation	NN
cord-018042-qt7055fw	62	9	and	and	CC
cord-018042-qt7055fw	62	10	BBB	BBB	NNP
cord-018042-qt7055fw	62	11	disruption	disruption	NN
cord-018042-qt7055fw	62	12	without	without	IN
cord-018042-qt7055fw	62	13	dysmyelination	dysmyelination	NN
cord-018042-qt7055fw	62	14	.	.	.
cord-018042-qt7055fw	63	1	Despite	despite	IN
cord-018042-qt7055fw	63	2	the	the	DT
cord-018042-qt7055fw	63	3	severity	severity	NN
cord-018042-qt7055fw	63	4	of	of	IN
cord-018042-qt7055fw	63	5	this	this	DT
cord-018042-qt7055fw	63	6	neurological	neurological	JJ
cord-018042-qt7055fw	63	7	disorder	disorder	NN
cord-018042-qt7055fw	63	8	(	(	-LRB-
cord-018042-qt7055fw	63	9	which	which	WDT
cord-018042-qt7055fw	63	10	resulted	result	VBD
cord-018042-qt7055fw	63	11	in	in	IN
cord-018042-qt7055fw	63	12	premature	premature	JJ
cord-018042-qt7055fw	63	13	death	death	NN
cord-018042-qt7055fw	63	14	)	)	-RRB-
cord-018042-qt7055fw	63	15	,	,	,
cord-018042-qt7055fw	63	16	there	there	EX
cord-018042-qt7055fw	63	17	was	be	VBD
cord-018042-qt7055fw	63	18	no	no	DT
cord-018042-qt7055fw	63	19	histological	histological	JJ
cord-018042-qt7055fw	63	20	evidence	evidence	NN
cord-018042-qt7055fw	63	21	of	of	IN
cord-018042-qt7055fw	63	22	damage	damage	NN
cord-018042-qt7055fw	63	23	to	to	IN
cord-018042-qt7055fw	63	24	neurons	neuron	NNS
cord-018042-qt7055fw	63	25	,	,	,
cord-018042-qt7055fw	63	26	myelin	myelin	NN
cord-018042-qt7055fw	63	27	or	or	CC
cord-018042-qt7055fw	63	28	axons	axon	NNS
cord-018042-qt7055fw	63	29	.	.	.
cord-018042-qt7055fw	64	1	Although	although	IN
cord-018042-qt7055fw	64	2	the	the	DT
cord-018042-qt7055fw	64	3	basis	basis	NN
cord-018042-qt7055fw	64	4	for	for	IN
cord-018042-qt7055fw	64	5	the	the	DT
cord-018042-qt7055fw	64	6	neurological	neurological	JJ
cord-018042-qt7055fw	64	7	dysfunction	dysfunction	NN
cord-018042-qt7055fw	64	8	developing	develop	VBG
cord-018042-qt7055fw	64	9	in	in	IN
cord-018042-qt7055fw	64	10	the	the	DT
cord-018042-qt7055fw	64	11	MBP	MBP	NNP
cord-018042-qt7055fw	64	12	-	-	HYPH
cord-018042-qt7055fw	64	13	KC	KC	NNP
cord-018042-qt7055fw	64	14	mice	mouse	NNS
cord-018042-qt7055fw	64	15	is	be	VBZ
cord-018042-qt7055fw	64	16	unknown	unknown	JJ
cord-018042-qt7055fw	64	17	,	,	,
cord-018042-qt7055fw	64	18	Tani	Tani	NNP
cord-018042-qt7055fw	64	19	et	et	NNP
cord-018042-qt7055fw	64	20	al	al	NNP
cord-018042-qt7055fw	64	21	.	.	.
cord-018042-qt7055fw	65	1	(	(	-LRB-
cord-018042-qt7055fw	65	2	1996	1996	CD
cord-018042-qt7055fw	65	3	)	)	-RRB-
cord-018042-qt7055fw	65	4	speculated	speculate	VBD
cord-018042-qt7055fw	65	5	that	that	IN
cord-018042-qt7055fw	65	6	this	this	DT
cord-018042-qt7055fw	65	7	might	may	MD
cord-018042-qt7055fw	65	8	be	be	VB
cord-018042-qt7055fw	65	9	due	due	JJ
cord-018042-qt7055fw	65	10	to	to	IN
cord-018042-qt7055fw	65	11	the	the	DT
cord-018042-qt7055fw	65	12	glial	glial	NN
cord-018042-qt7055fw	65	13	and	and	CC
cord-018042-qt7055fw	65	14	BBB	BBB	NNP
cord-018042-qt7055fw	65	15	perturbations	perturbation	NNS
cord-018042-qt7055fw	65	16	.	.	.
cord-018042-qt7055fw	66	1	It	-PRON-	PRP
cord-018042-qt7055fw	66	2	is	be	VBZ
cord-018042-qt7055fw	66	3	also	also	RB
cord-018042-qt7055fw	66	4	possible	possible	JJ
cord-018042-qt7055fw	66	5	as	as	IN
cord-018042-qt7055fw	66	6	the	the	DT
cord-018042-qt7055fw	66	7	authors	author	NNS
cord-018042-qt7055fw	66	8	suggested	suggest	VBD
cord-018042-qt7055fw	66	9	that	that	IN
cord-018042-qt7055fw	66	10	chronic	chronic	JJ
cord-018042-qt7055fw	66	11	exposure	exposure	NN
cord-018042-qt7055fw	66	12	of	of	IN
cord-018042-qt7055fw	66	13	neurons	neuron	NNS
cord-018042-qt7055fw	66	14	to	to	IN
cord-018042-qt7055fw	66	15	the	the	DT
cord-018042-qt7055fw	66	16	chemokine	chemokine	NN
cord-018042-qt7055fw	66	17	may	may	MD
cord-018042-qt7055fw	66	18	directly	directly	RB
cord-018042-qt7055fw	66	19	compromise	compromise	VB
cord-018042-qt7055fw	66	20	their	-PRON-	PRP$
cord-018042-qt7055fw	66	21	function	function	NN
cord-018042-qt7055fw	66	22	.	.	.
cord-018042-qt7055fw	67	1	In	in	IN
cord-018042-qt7055fw	67	2	support	support	NN
cord-018042-qt7055fw	67	3	of	of	IN
cord-018042-qt7055fw	67	4	such	such	PDT
cord-018042-qt7055fw	67	5	a	a	DT
cord-018042-qt7055fw	67	6	mechanism	mechanism	NN
cord-018042-qt7055fw	67	7	,	,	,
cord-018042-qt7055fw	67	8	CXCL1	CXCL1	NNP
cord-018042-qt7055fw	67	9	can	can	MD
cord-018042-qt7055fw	67	10	enhance	enhance	VB
cord-018042-qt7055fw	67	11	both	both	DT
cord-018042-qt7055fw	67	12	stimulus	stimulus	NN
cord-018042-qt7055fw	67	13	-	-	HYPH
cord-018042-qt7055fw	67	14	evoked	evoke	VBN
cord-018042-qt7055fw	67	15	and	and	CC
cord-018042-qt7055fw	67	16	spontaneous	spontaneous	JJ
cord-018042-qt7055fw	67	17	postsynaptic	postsynaptic	JJ
cord-018042-qt7055fw	67	18	currents	current	NNS
cord-018042-qt7055fw	67	19	,	,	,
cord-018042-qt7055fw	67	20	and	and	CC
cord-018042-qt7055fw	67	21	increase	increase	VB
cord-018042-qt7055fw	67	22	neurotransmitter	neurotransmitter	NN
cord-018042-qt7055fw	67	23	release	release	NN
cord-018042-qt7055fw	67	24	and	and	CC
cord-018042-qt7055fw	67	25	reduce	reduce	VB
cord-018042-qt7055fw	67	26	long	long	JJ
cord-018042-qt7055fw	67	27	-	-	HYPH
cord-018042-qt7055fw	67	28	term	term	NN
cord-018042-qt7055fw	67	29	depression	depression	NN
cord-018042-qt7055fw	67	30	,	,	,
cord-018042-qt7055fw	67	31	in	in	IN
cord-018042-qt7055fw	67	32	Purkinje	Purkinje	NNP
cord-018042-qt7055fw	67	33	neurons	neuron	NNS
cord-018042-qt7055fw	67	34	.	.	.
cord-018042-qt7055fw	68	1	On	on	IN
cord-018042-qt7055fw	68	2	the	the	DT
cord-018042-qt7055fw	68	3	other	other	JJ
cord-018042-qt7055fw	68	4	hand	hand	NN
cord-018042-qt7055fw	68	5	,	,	,
cord-018042-qt7055fw	68	6	despite	despite	IN
cord-018042-qt7055fw	68	7	accumulating	accumulate	VBG
cord-018042-qt7055fw	68	8	evidence	evidence	NN
cord-018042-qt7055fw	68	9	that	that	IN
cord-018042-qt7055fw	68	10	CXCL1	CXCL1	NNP
cord-018042-qt7055fw	68	11	influences	influence	NNS
cord-018042-qt7055fw	68	12	oligodendrocyte	oligodendrocyte	NNP
cord-018042-qt7055fw	68	13	precursor	precursor	NN
cord-018042-qt7055fw	68	14	cell	cell	NN
cord-018042-qt7055fw	68	15	and	and	CC
cord-018042-qt7055fw	68	16	differentiated	differentiate	VBN
cord-018042-qt7055fw	68	17	oligodendrocyte	oligodendrocyte	NNP
cord-018042-qt7055fw	68	18	function	function	NN
cord-018042-qt7055fw	68	19	both	both	CC
cord-018042-qt7055fw	68	20	in	in	IN
cord-018042-qt7055fw	68	21	vitro	vitro	FW
cord-018042-qt7055fw	68	22	and	and	CC
cord-018042-qt7055fw	68	23	in	in	IN
cord-018042-qt7055fw	68	24	vivo	vivo	NN
cord-018042-qt7055fw	68	25	,	,	,
cord-018042-qt7055fw	68	26	surprisingly	surprisingly	RB
cord-018042-qt7055fw	68	27	,	,	,
cord-018042-qt7055fw	68	28	MBP	MBP	NNP
cord-018042-qt7055fw	68	29	-	-	HYPH
cord-018042-qt7055fw	68	30	KC	KC	NNP
cord-018042-qt7055fw	68	31	mice	mouse	NNS
cord-018042-qt7055fw	68	32	were	be	VBD
cord-018042-qt7055fw	68	33	reported	report	VBN
cord-018042-qt7055fw	68	34	to	to	TO
cord-018042-qt7055fw	68	35	exhibit	exhibit	VB
cord-018042-qt7055fw	68	36	normal	normal	JJ
cord-018042-qt7055fw	68	37	CNS	CNS	NNP
cord-018042-qt7055fw	68	38	myelination	myelination	NN
cord-018042-qt7055fw	68	39	both	both	DT
cord-018042-qt7055fw	68	40	in	in	IN
cord-018042-qt7055fw	68	41	the	the	DT
cord-018042-qt7055fw	68	42	acute	acute	JJ
cord-018042-qt7055fw	68	43	and	and	CC
cord-018042-qt7055fw	68	44	chronic	chronic	JJ
cord-018042-qt7055fw	68	45	disorders	disorder	NNS
cord-018042-qt7055fw	68	46	.	.	.
cord-018042-qt7055fw	69	1	CXCL10	CXCL10	NNP
cord-018042-qt7055fw	69	2	(	(	-LRB-
cord-018042-qt7055fw	69	3	also	also	RB
cord-018042-qt7055fw	69	4	known	know	VBN
cord-018042-qt7055fw	69	5	as	as	IN
cord-018042-qt7055fw	69	6	IP-10	IP-10	NNP
cord-018042-qt7055fw	69	7	)	)	-RRB-
cord-018042-qt7055fw	69	8	belongs	belong	VBZ
cord-018042-qt7055fw	69	9	to	to	IN
cord-018042-qt7055fw	69	10	a	a	DT
cord-018042-qt7055fw	69	11	sub	sub	NN
cord-018042-qt7055fw	69	12	-	-	NN
cord-018042-qt7055fw	69	13	family	family	NN
cord-018042-qt7055fw	69	14	of	of	IN
cord-018042-qt7055fw	69	15	chemokines	chemokine	NNS
cord-018042-qt7055fw	69	16	that	that	WDT
cord-018042-qt7055fw	69	17	include	include	VBP
cord-018042-qt7055fw	69	18	CXCL9	CXCL9	NNP
cord-018042-qt7055fw	69	19	(	(	-LRB-
cord-018042-qt7055fw	69	20	MIG	MIG	NNP
cord-018042-qt7055fw	69	21	)	)	-RRB-
cord-018042-qt7055fw	69	22	and	and	CC
cord-018042-qt7055fw	69	23	CXCL11	CXCL11	NNP
cord-018042-qt7055fw	69	24	(	(	-LRB-
cord-018042-qt7055fw	69	25	ITAC	ITAC	NNP
cord-018042-qt7055fw	69	26	)	)	-RRB-
cord-018042-qt7055fw	69	27	within	within	IN
cord-018042-qt7055fw	69	28	the	the	DT
cord-018042-qt7055fw	69	29	CXC	CXC	NNP
cord-018042-qt7055fw	69	30	family	family	NN
cord-018042-qt7055fw	69	31	.	.	.
cord-018042-qt7055fw	70	1	Unlike	unlike	IN
cord-018042-qt7055fw	70	2	CXCL1	CXCL1	NNP
cord-018042-qt7055fw	70	3	,	,	,
cord-018042-qt7055fw	70	4	the	the	DT
cord-018042-qt7055fw	70	5	chemokines	chemokine	NNS
cord-018042-qt7055fw	70	6	in	in	IN
cord-018042-qt7055fw	70	7	this	this	DT
cord-018042-qt7055fw	70	8	sub	sub	NN
cord-018042-qt7055fw	70	9	-	-	JJ
cord-018042-qt7055fw	70	10	family	family	NN
cord-018042-qt7055fw	70	11	lack	lack	VBP
cord-018042-qt7055fw	70	12	the	the	DT
cord-018042-qt7055fw	70	13	N	n	CD
cord-018042-qt7055fw	70	14	-	-	HYPH
cord-018042-qt7055fw	70	15	terminal	terminal	NN
cord-018042-qt7055fw	70	16	ELR	ELR	NNP
cord-018042-qt7055fw	70	17	-	-	HYPH
cord-018042-qt7055fw	70	18	amino	amino	NN
cord-018042-qt7055fw	70	19	acid	acid	NN
cord-018042-qt7055fw	70	20	motif	motif	NN
cord-018042-qt7055fw	70	21	.	.	.
cord-018042-qt7055fw	71	1	Expression	expression	NN
cord-018042-qt7055fw	71	2	of	of	IN
cord-018042-qt7055fw	71	3	the	the	DT
cord-018042-qt7055fw	71	4	CXCL9	cxcl9	NN
cord-018042-qt7055fw	71	5	,	,	,
cord-018042-qt7055fw	71	6	CXCL10	CXCL10	NNP
cord-018042-qt7055fw	71	7	and	and	CC
cord-018042-qt7055fw	71	8	CXCL11	CXCL11	NNP
cord-018042-qt7055fw	71	9	genes	gene	NNS
cord-018042-qt7055fw	71	10	is	be	VBZ
cord-018042-qt7055fw	71	11	induced	induce	VBN
cord-018042-qt7055fw	71	12	by	by	IN
cord-018042-qt7055fw	71	13	the	the	DT
cord-018042-qt7055fw	71	14	cytokine	cytokine	NN
cord-018042-qt7055fw	71	15	IFN	IFN	NNP
cord-018042-qt7055fw	71	16	-	-	HYPH
cord-018042-qt7055fw	71	17	γ	γ	NNP
cord-018042-qt7055fw	71	18	and	and	CC
cord-018042-qt7055fw	71	19	all	all	DT
cord-018042-qt7055fw	71	20	three	three	CD
cord-018042-qt7055fw	71	21	chemokines	chemokine	NNS
cord-018042-qt7055fw	71	22	bind	bind	VBP
cord-018042-qt7055fw	71	23	to	to	IN
cord-018042-qt7055fw	71	24	a	a	DT
cord-018042-qt7055fw	71	25	common	common	JJ
cord-018042-qt7055fw	71	26	receptor	receptor	NN
cord-018042-qt7055fw	71	27	,	,	,
cord-018042-qt7055fw	71	28	CXCR3	cxcr3	XX
cord-018042-qt7055fw	71	29	.	.	.
cord-018042-qt7055fw	72	1	High	high	JJ
cord-018042-qt7055fw	72	2	levels	level	NNS
cord-018042-qt7055fw	72	3	of	of	IN
cord-018042-qt7055fw	72	4	CXCR3	cxcr3	NN
cord-018042-qt7055fw	72	5	can	can	MD
cord-018042-qt7055fw	72	6	be	be	VB
cord-018042-qt7055fw	72	7	found	find	VBN
cord-018042-qt7055fw	72	8	principally	principally	RB
cord-018042-qt7055fw	72	9	on	on	IN
cord-018042-qt7055fw	72	10	activated	activate	VBN
cord-018042-qt7055fw	72	11	CD4	CD4	NNP
cord-018042-qt7055fw	72	12	+	+	CC
cord-018042-qt7055fw	72	13	Th1	Th1	NNP
cord-018042-qt7055fw	72	14	and	and	CC
cord-018042-qt7055fw	72	15	CD8	CD8	NNP
cord-018042-qt7055fw	72	16	+	+	CC
cord-018042-qt7055fw	72	17	T	T	NNP
cord-018042-qt7055fw	72	18	-	-	HYPH
cord-018042-qt7055fw	72	19	cells	cell	NNS
cord-018042-qt7055fw	72	20	and	and	CC
cord-018042-qt7055fw	72	21	NK	nk	NN
cord-018042-qt7055fw	72	22	-	-	HYPH
cord-018042-qt7055fw	72	23	cells	cell	NNS
cord-018042-qt7055fw	73	1	(	(	-LRB-
cord-018042-qt7055fw	73	2	Taub	Taub	NNP
cord-018042-qt7055fw	73	3	et	et	NNP
cord-018042-qt7055fw	73	4	al	al	NNP
cord-018042-qt7055fw	73	5	.	.	.
cord-018042-qt7055fw	74	1	,	,	,
cord-018042-qt7055fw	74	2	1993	1993	CD
cord-018042-qt7055fw	74	3	(	(	-LRB-
cord-018042-qt7055fw	74	4	Taub	Taub	NNP
cord-018042-qt7055fw	74	5	et	et	NNP
cord-018042-qt7055fw	74	6	al	al	NNP
cord-018042-qt7055fw	74	7	.	.	.
cord-018042-qt7055fw	75	1	,	,	,
cord-018042-qt7055fw	75	2	,	,	,
cord-018042-qt7055fw	75	3	1996a	1996a	CD
cord-018042-qt7055fw	75	4	Hopkins	Hopkins	NNP
cord-018042-qt7055fw	75	5	and	and	CC
cord-018042-qt7055fw	75	6	Rothwell	Rothwell	NNP
cord-018042-qt7055fw	75	7	,	,	,
cord-018042-qt7055fw	75	8	1995	1995	CD
cord-018042-qt7055fw	75	9	;	;	:
cord-018042-qt7055fw	75	10	Liao	Liao	NNP
cord-018042-qt7055fw	75	11	et	et	NNP
cord-018042-qt7055fw	75	12	al	al	NNP
cord-018042-qt7055fw	75	13	.	.	NNP
cord-018042-qt7055fw	75	14	,	,	,
cord-018042-qt7055fw	75	15	1995	1995	CD
cord-018042-qt7055fw	75	16	;	;	:
cord-018042-qt7055fw	75	17	Loetscher	Loetscher	NNP
cord-018042-qt7055fw	75	18	et	et	NNP
cord-018042-qt7055fw	75	19	al	al	NNP
cord-018042-qt7055fw	75	20	.	.	.
cord-018042-qt7055fw	76	1	,	,	,
cord-018042-qt7055fw	76	2	1996	1996	CD
cord-018042-qt7055fw	76	3	;	;	:
cord-018042-qt7055fw	76	4	Cole	Cole	NNP
cord-018042-qt7055fw	76	5	et	et	NNP
cord-018042-qt7055fw	76	6	al	al	NNP
cord-018042-qt7055fw	76	7	.	.	NNP
cord-018042-qt7055fw	76	8	,	,	,
cord-018042-qt7055fw	76	9	1998	1998	CD
cord-018042-qt7055fw	76	10	)	)	-RRB-
cord-018042-qt7055fw	76	11	.	.	.
cord-018042-qt7055fw	77	1	In	in	IN
cord-018042-qt7055fw	77	2	keeping	keep	VBG
cord-018042-qt7055fw	77	3	with	with	IN
cord-018042-qt7055fw	77	4	this	this	DT
cord-018042-qt7055fw	77	5	cellular	cellular	JJ
cord-018042-qt7055fw	77	6	receptor	receptor	NN
cord-018042-qt7055fw	77	7	distribution	distribution	NN
cord-018042-qt7055fw	77	8	,	,	,
cord-018042-qt7055fw	77	9	CXC9	CXC9	NNP
cord-018042-qt7055fw	77	10	,	,	,
cord-018042-qt7055fw	77	11	CXCL10	CXCL10	NNP
cord-018042-qt7055fw	77	12	and	and	CC
cord-018042-qt7055fw	77	13	CXCL11	CXCL11	NNP
cord-018042-qt7055fw	77	14	all	all	DT
cord-018042-qt7055fw	77	15	promote	promote	VBP
cord-018042-qt7055fw	77	16	the	the	DT
cord-018042-qt7055fw	77	17	trafficking	trafficking	NN
cord-018042-qt7055fw	77	18	of	of	IN
cord-018042-qt7055fw	77	19	these	these	DT
cord-018042-qt7055fw	77	20	immune	immune	JJ
cord-018042-qt7055fw	77	21	cells	cell	NNS
cord-018042-qt7055fw	77	22	in	in	IN
cord-018042-qt7055fw	77	23	vitro	vitro	FW
cord-018042-qt7055fw	77	24	and	and	CC
cord-018042-qt7055fw	77	25	are	be	VBP
cord-018042-qt7055fw	77	26	strongly	strongly	RB
cord-018042-qt7055fw	77	27	implicated	implicate	VBN
cord-018042-qt7055fw	77	28	in	in	IN
cord-018042-qt7055fw	77	29	the	the	DT
cord-018042-qt7055fw	77	30	generation	generation	NN
cord-018042-qt7055fw	77	31	of	of	IN
cord-018042-qt7055fw	77	32	type	type	NN
cord-018042-qt7055fw	78	1	I	-PRON-	PRP
cord-018042-qt7055fw	78	2	immune	immune	VBP
cord-018042-qt7055fw	78	3	responses	response	NNS
cord-018042-qt7055fw	78	4	associated	associate	VBN
cord-018042-qt7055fw	78	5	with	with	IN
cord-018042-qt7055fw	78	6	anti	anti	JJ
cord-018042-qt7055fw	78	7	-	-	JJ
cord-018042-qt7055fw	78	8	viral	viral	JJ
cord-018042-qt7055fw	78	9	host	host	NN
cord-018042-qt7055fw	78	10	defense	defense	NN
cord-018042-qt7055fw	78	11	,	,	,
cord-018042-qt7055fw	78	12	transplant	transplant	NN
cord-018042-qt7055fw	78	13	rejection	rejection	NN
cord-018042-qt7055fw	78	14	and	and	CC
cord-018042-qt7055fw	78	15	autoimmunity	autoimmunity	NN
cord-018042-qt7055fw	78	16	(	(	-LRB-
cord-018042-qt7055fw	78	17	Liu	Liu	NNP
cord-018042-qt7055fw	78	18	et	et	NNP
cord-018042-qt7055fw	78	19	al	al	NNP
cord-018042-qt7055fw	78	20	.	.	NNP
cord-018042-qt7055fw	78	21	,	,	,
cord-018042-qt7055fw	78	22	2005	2005	CD
cord-018042-qt7055fw	78	23	)	)	-RRB-
cord-018042-qt7055fw	78	24	.	.	.
cord-018042-qt7055fw	79	1	Evidence	evidence	NN
cord-018042-qt7055fw	79	2	from	from	IN
cord-018042-qt7055fw	79	3	rodent	rodent	NN
cord-018042-qt7055fw	79	4	studies	study	NNS
cord-018042-qt7055fw	79	5	indicate	indicate	VBP
cord-018042-qt7055fw	79	6	that	that	IN
cord-018042-qt7055fw	79	7	a	a	DT
cord-018042-qt7055fw	79	8	functional	functional	JJ
cord-018042-qt7055fw	79	9	CXCR3	cxcr3	NN
cord-018042-qt7055fw	79	10	receptor	receptor	NN
cord-018042-qt7055fw	79	11	exists	exist	VBZ
cord-018042-qt7055fw	79	12	on	on	IN
cord-018042-qt7055fw	79	13	microglia	microglia	NNS
cord-018042-qt7055fw	79	14	(	(	-LRB-
cord-018042-qt7055fw	79	15	Rappert	Rappert	NNP
cord-018042-qt7055fw	79	16	et	et	NNP
cord-018042-qt7055fw	79	17	al	al	NNP
cord-018042-qt7055fw	79	18	.	.	NNP
cord-018042-qt7055fw	79	19	,	,	,
cord-018042-qt7055fw	79	20	2004	2004	CD
cord-018042-qt7055fw	79	21	)	)	-RRB-
cord-018042-qt7055fw	79	22	and	and	CC
cord-018042-qt7055fw	79	23	neurons	neuron	NNS
cord-018042-qt7055fw	79	24	(	(	-LRB-
cord-018042-qt7055fw	79	25	Nelson	Nelson	NNP
cord-018042-qt7055fw	79	26	and	and	CC
cord-018042-qt7055fw	79	27	Gruol	Gruol	NNP
cord-018042-qt7055fw	79	28	,	,	,
cord-018042-qt7055fw	79	29	2004	2004	CD
cord-018042-qt7055fw	79	30	)	)	-RRB-
cord-018042-qt7055fw	79	31	.	.	.
cord-018042-qt7055fw	80	1	Descriptive	descriptive	JJ
cord-018042-qt7055fw	80	2	studies	study	NNS
cord-018042-qt7055fw	80	3	confirm	confirm	VBP
cord-018042-qt7055fw	80	4	the	the	DT
cord-018042-qt7055fw	80	5	presence	presence	NN
cord-018042-qt7055fw	80	6	of	of	IN
cord-018042-qt7055fw	80	7	high	high	JJ
cord-018042-qt7055fw	80	8	levels	level	NNS
cord-018042-qt7055fw	80	9	of	of	IN
cord-018042-qt7055fw	80	10	CXCL10	CXCL10	NNP
cord-018042-qt7055fw	80	11	RNA	RNA	NNP
cord-018042-qt7055fw	80	12	and	and	CC
cord-018042-qt7055fw	80	13	protein	protein	NN
cord-018042-qt7055fw	80	14	,	,	,
cord-018042-qt7055fw	80	15	particularly	particularly	RB
cord-018042-qt7055fw	80	16	in	in	IN
cord-018042-qt7055fw	80	17	astrocytes	astrocyte	NNS
cord-018042-qt7055fw	80	18	and	and	CC
cord-018042-qt7055fw	80	19	neurons	neuron	NNS
cord-018042-qt7055fw	80	20	,	,	,
cord-018042-qt7055fw	80	21	in	in	IN
cord-018042-qt7055fw	80	22	a	a	DT
cord-018042-qt7055fw	80	23	variety	variety	NN
cord-018042-qt7055fw	80	24	of	of	IN
cord-018042-qt7055fw	80	25	experimental	experimental	JJ
cord-018042-qt7055fw	80	26	and	and	CC
cord-018042-qt7055fw	80	27	human	human	JJ
cord-018042-qt7055fw	80	28	neurological	neurological	JJ
cord-018042-qt7055fw	80	29	diseases	disease	NNS
cord-018042-qt7055fw	80	30	including	include	VBG
cord-018042-qt7055fw	80	31	viral	viral	JJ
cord-018042-qt7055fw	80	32	infection	infection	NN
cord-018042-qt7055fw	80	33	and	and	CC
cord-018042-qt7055fw	80	34	autoimmune	autoimmune	JJ
cord-018042-qt7055fw	80	35	diseases	disease	NNS
cord-018042-qt7055fw	80	36	(	(	-LRB-
cord-018042-qt7055fw	80	37	Klein	Klein	NNP
cord-018042-qt7055fw	80	38	,	,	,
cord-018042-qt7055fw	80	39	2004	2004	CD
cord-018042-qt7055fw	80	40	;	;	:
cord-018042-qt7055fw	80	41	Liu	Liu	NNP
cord-018042-qt7055fw	80	42	et	et	NNP
cord-018042-qt7055fw	80	43	al	al	NNP
cord-018042-qt7055fw	80	44	.	.	NNP
cord-018042-qt7055fw	80	45	,	,	,
cord-018042-qt7055fw	80	46	2005	2005	CD
cord-018042-qt7055fw	80	47	)	)	-RRB-
cord-018042-qt7055fw	80	48	.	.	.
cord-018042-qt7055fw	81	1	A	a	DT
cord-018042-qt7055fw	81	2	transgenic	transgenic	JJ
cord-018042-qt7055fw	81	3	mouse	mouse	NN
cord-018042-qt7055fw	81	4	model	model	NN
cord-018042-qt7055fw	81	5	was	be	VBD
cord-018042-qt7055fw	81	6	developed	develop	VBN
cord-018042-qt7055fw	81	7	in	in	IN
cord-018042-qt7055fw	81	8	which	which	WDT
cord-018042-qt7055fw	81	9	the	the	DT
cord-018042-qt7055fw	81	10	GFAP	GFAP	NNP
cord-018042-qt7055fw	81	11	promoter	promoter	NN
cord-018042-qt7055fw	81	12	was	be	VBD
cord-018042-qt7055fw	81	13	used	use	VBN
cord-018042-qt7055fw	81	14	to	to	TO
cord-018042-qt7055fw	81	15	accomplish	accomplish	VB
cord-018042-qt7055fw	81	16	astrocyte	astrocyte	RB
cord-018042-qt7055fw	81	17	-	-	HYPH
cord-018042-qt7055fw	81	18	targeted	target	VBN
cord-018042-qt7055fw	81	19	production	production	NN
cord-018042-qt7055fw	81	20	of	of	IN
cord-018042-qt7055fw	81	21	CXCL10	CXCL10	NNP
cord-018042-qt7055fw	81	22	(	(	-LRB-
cord-018042-qt7055fw	81	23	see	see	VB
cord-018042-qt7055fw	81	24	Fig	Fig	NNP
cord-018042-qt7055fw	81	25	.	.	.
cord-018042-qt7055fw	82	1	10	10	CD
cord-018042-qt7055fw	82	2	.1	.1	CD
cord-018042-qt7055fw	82	3	)	)	-RRB-
cord-018042-qt7055fw	83	1	(	(	-LRB-
cord-018042-qt7055fw	83	2	Boztug	Boztug	NNP
cord-018042-qt7055fw	83	3	et	et	NNP
cord-018042-qt7055fw	83	4	al	al	NNP
cord-018042-qt7055fw	83	5	.	.	NNP
cord-018042-qt7055fw	83	6	,	,	,
cord-018042-qt7055fw	83	7	2002	2002	CD
cord-018042-qt7055fw	83	8	)	)	-RRB-
cord-018042-qt7055fw	83	9	.	.	.
cord-018042-qt7055fw	84	1	Astrocyte	Astrocyte	NNP
cord-018042-qt7055fw	84	2	-	-	HYPH
cord-018042-qt7055fw	84	3	localized	localize	VBN
cord-018042-qt7055fw	84	4	production	production	NN
cord-018042-qt7055fw	84	5	of	of	IN
cord-018042-qt7055fw	84	6	the	the	DT
cord-018042-qt7055fw	84	7	GFAP	GFAP	NNP
cord-018042-qt7055fw	84	8	-	-	HYPH
cord-018042-qt7055fw	84	9	transgene	transgene	NN
cord-018042-qt7055fw	84	10	encoded	encode	VBD
cord-018042-qt7055fw	84	11	CXCL10	CXCL10	NNP
cord-018042-qt7055fw	84	12	RNA	RNA	NNP
cord-018042-qt7055fw	84	13	was	be	VBD
cord-018042-qt7055fw	84	14	confirmed	confirm	VBN
cord-018042-qt7055fw	84	15	while	while	IN
cord-018042-qt7055fw	84	16	production	production	NN
cord-018042-qt7055fw	84	17	of	of	IN
cord-018042-qt7055fw	84	18	CXCL10	CXCL10	NNP
cord-018042-qt7055fw	84	19	at	at	IN
cord-018042-qt7055fw	84	20	the	the	DT
cord-018042-qt7055fw	84	21	protein	protein	NN
cord-018042-qt7055fw	84	22	level	level	NN
cord-018042-qt7055fw	84	23	was	be	VBD
cord-018042-qt7055fw	84	24	demonstrated	demonstrate	VBN
cord-018042-qt7055fw	84	25	by	by	IN
cord-018042-qt7055fw	84	26	immunoblotting	immunoblotte	VBG
cord-018042-qt7055fw	84	27	.	.	.
cord-018042-qt7055fw	85	1	The	the	DT
cord-018042-qt7055fw	85	2	levels	level	NNS
cord-018042-qt7055fw	85	3	of	of	IN
cord-018042-qt7055fw	85	4	these	these	DT
cord-018042-qt7055fw	85	5	transgene	transgene	NN
cord-018042-qt7055fw	85	6	-	-	HYPH
cord-018042-qt7055fw	85	7	encoded	encode	VBN
cord-018042-qt7055fw	85	8	products	product	NNS
cord-018042-qt7055fw	85	9	were	be	VBD
cord-018042-qt7055fw	85	10	shown	show	VBN
cord-018042-qt7055fw	85	11	to	to	TO
cord-018042-qt7055fw	85	12	be	be	VB
cord-018042-qt7055fw	85	13	similar	similar	JJ
cord-018042-qt7055fw	85	14	to	to	IN
cord-018042-qt7055fw	85	15	levels	level	NNS
cord-018042-qt7055fw	85	16	of	of	IN
cord-018042-qt7055fw	85	17	the	the	DT
cord-018042-qt7055fw	85	18	endogenous	endogenous	JJ
cord-018042-qt7055fw	85	19	CXCL10	CXCL10	NNP
cord-018042-qt7055fw	85	20	induced	induce	VBN
cord-018042-qt7055fw	85	21	following	follow	VBG
cord-018042-qt7055fw	85	22	viral	viral	JJ
cord-018042-qt7055fw	85	23	infection	infection	NN
cord-018042-qt7055fw	85	24	of	of	IN
cord-018042-qt7055fw	85	25	the	the	DT
cord-018042-qt7055fw	85	26	mouse	mouse	NN
cord-018042-qt7055fw	85	27	brain	brain	NN
cord-018042-qt7055fw	85	28	confirming	confirm	VBG
cord-018042-qt7055fw	85	29	the	the	DT
cord-018042-qt7055fw	85	30	pathophysiological	pathophysiological	JJ
cord-018042-qt7055fw	85	31	relevance	relevance	NN
cord-018042-qt7055fw	85	32	of	of	IN
cord-018042-qt7055fw	85	33	this	this	DT
cord-018042-qt7055fw	85	34	model	model	NN
cord-018042-qt7055fw	85	35	.	.	.
cord-018042-qt7055fw	86	1	These	these	DT
cord-018042-qt7055fw	86	2	GFAP	GFAP	NNP
cord-018042-qt7055fw	86	3	-	-	HYPH
cord-018042-qt7055fw	86	4	CXCL10	cxcl10	CD
cord-018042-qt7055fw	86	5	transgenic	transgenic	JJ
cord-018042-qt7055fw	86	6	mice	mouse	NNS
cord-018042-qt7055fw	86	7	bred	breed	VBD
cord-018042-qt7055fw	86	8	normally	normally	RB
cord-018042-qt7055fw	86	9	and	and	CC
cord-018042-qt7055fw	86	10	appeared	appear	VBD
cord-018042-qt7055fw	86	11	physically	physically	RB
cord-018042-qt7055fw	86	12	unimpaired	unimpaired	JJ
cord-018042-qt7055fw	86	13	.	.	.
cord-018042-qt7055fw	87	1	Histological	histological	JJ
cord-018042-qt7055fw	87	2	evaluation	evaluation	NN
cord-018042-qt7055fw	87	3	of	of	IN
cord-018042-qt7055fw	87	4	the	the	DT
cord-018042-qt7055fw	87	5	brain	brain	NN
cord-018042-qt7055fw	87	6	revealed	reveal	VBD
cord-018042-qt7055fw	87	7	a	a	DT
cord-018042-qt7055fw	87	8	predominantly	predominantly	RB
cord-018042-qt7055fw	87	9	subarachnoidal	subarachnoidal	JJ
cord-018042-qt7055fw	87	10	and	and	CC
cord-018042-qt7055fw	87	11	meningeal	meningeal	JJ
cord-018042-qt7055fw	87	12	accumulation	accumulation	NN
cord-018042-qt7055fw	87	13	of	of	IN
cord-018042-qt7055fw	87	14	mixed	mixed	JJ
cord-018042-qt7055fw	87	15	leukocytes	leukocyte	NNS
cord-018042-qt7055fw	87	16	with	with	IN
cord-018042-qt7055fw	87	17	only	only	JJ
cord-018042-qt7055fw	87	18	minor	minor	JJ
cord-018042-qt7055fw	87	19	parenchymal	parenchymal	NN
cord-018042-qt7055fw	87	20	infiltration	infiltration	NN
cord-018042-qt7055fw	87	21	(	(	-LRB-
cord-018042-qt7055fw	87	22	see	see	VB
cord-018042-qt7055fw	87	23	Fig	Fig	NNP
cord-018042-qt7055fw	87	24	.	.	.
cord-018042-qt7055fw	88	1	10	10	CD
cord-018042-qt7055fw	88	2	.2	.2	CD
cord-018042-qt7055fw	88	3	)	)	-RRB-
cord-018042-qt7055fw	88	4	.	.	.
cord-018042-qt7055fw	89	1	The	the	DT
cord-018042-qt7055fw	89	2	accumulation	accumulation	NN
cord-018042-qt7055fw	89	3	of	of	IN
cord-018042-qt7055fw	89	4	leukocytes	leukocyte	NNS
cord-018042-qt7055fw	89	5	in	in	IN
cord-018042-qt7055fw	89	6	the	the	DT
cord-018042-qt7055fw	89	7	brain	brain	NN
cord-018042-qt7055fw	89	8	of	of	IN
cord-018042-qt7055fw	89	9	these	these	DT
cord-018042-qt7055fw	89	10	transgenic	transgenic	JJ
cord-018042-qt7055fw	89	11	mice	mouse	NNS
cord-018042-qt7055fw	89	12	was	be	VBD
cord-018042-qt7055fw	89	13	markedly	markedly	RB
cord-018042-qt7055fw	89	14	amplified	amplify	VBN
cord-018042-qt7055fw	89	15	by	by	IN
cord-018042-qt7055fw	89	16	systemic	systemic	JJ
cord-018042-qt7055fw	89	17	immune	immune	JJ
cord-018042-qt7055fw	89	18	challenge	challenge	NN
cord-018042-qt7055fw	89	19	after	after	IN
cord-018042-qt7055fw	89	20	immunization	immunization	NN
cord-018042-qt7055fw	89	21	with	with	IN
cord-018042-qt7055fw	89	22	complete	complete	JJ
cord-018042-qt7055fw	89	23	Freund	Freund	NNP
cord-018042-qt7055fw	89	24	's	's	POS
cord-018042-qt7055fw	89	25	adjuvant	adjuvant	NN
cord-018042-qt7055fw	89	26	and	and	CC
cord-018042-qt7055fw	89	27	pertussis	pertussis	NN
cord-018042-qt7055fw	89	28	toxin	toxin	NN
cord-018042-qt7055fw	89	29	.	.	.
cord-018042-qt7055fw	90	1	Immunophenotypic	immunophenotypic	JJ
cord-018042-qt7055fw	90	2	characterization	characterization	NN
cord-018042-qt7055fw	90	3	of	of	IN
cord-018042-qt7055fw	90	4	these	these	DT
cord-018042-qt7055fw	90	5	infiltrates	infiltrate	NNS
cord-018042-qt7055fw	90	6	revealed	reveal	VBN
cord-018042-qt7055fw	90	7	surprisingly	surprisingly	RB
cord-018042-qt7055fw	90	8	,	,	,
cord-018042-qt7055fw	90	9	that	that	IN
cord-018042-qt7055fw	90	10	the	the	DT
cord-018042-qt7055fw	90	11	majority	majority	NN
cord-018042-qt7055fw	90	12	of	of	IN
cord-018042-qt7055fw	90	13	infiltrating	infiltrate	VBG
cord-018042-qt7055fw	90	14	leukocytes	leukocyte	NNS
cord-018042-qt7055fw	90	15	Generation	generation	NN
cord-018042-qt7055fw	90	16	of	of	IN
cord-018042-qt7055fw	90	17	transgenic	transgenic	JJ
cord-018042-qt7055fw	90	18	mice	mouse	NNS
cord-018042-qt7055fw	90	19	with	with	IN
cord-018042-qt7055fw	90	20	CXCL10	CXCL10	NNP
cord-018042-qt7055fw	90	21	gene	gene	NN
cord-018042-qt7055fw	90	22	production	production	NN
cord-018042-qt7055fw	90	23	targeted	target	VBN
cord-018042-qt7055fw	90	24	to	to	IN
cord-018042-qt7055fw	90	25	astrocytes	astrocyte	NNS
cord-018042-qt7055fw	90	26	.	.	.
cord-018042-qt7055fw	91	1	A	a	DT
cord-018042-qt7055fw	91	2	cDNA	cdna	NN
cord-018042-qt7055fw	91	3	encoding	encode	VBG
cord-018042-qt7055fw	91	4	murine	murine	JJ
cord-018042-qt7055fw	91	5	CXCL10	CXCL10	NNP
cord-018042-qt7055fw	91	6	was	be	VBD
cord-018042-qt7055fw	91	7	inserted	insert	VBN
cord-018042-qt7055fw	91	8	downstream	downstream	RB
cord-018042-qt7055fw	91	9	of	of	IN
cord-018042-qt7055fw	91	10	the	the	DT
cord-018042-qt7055fw	91	11	murine	murine	JJ
cord-018042-qt7055fw	91	12	GFAP	GFAP	NNP
cord-018042-qt7055fw	91	13	promoter	promoter	NN
cord-018042-qt7055fw	91	14	and	and	CC
cord-018042-qt7055fw	91	15	upstream	upstream	RB
cord-018042-qt7055fw	91	16	of	of	IN
cord-018042-qt7055fw	91	17	a	a	DT
cord-018042-qt7055fw	91	18	human	human	JJ
cord-018042-qt7055fw	91	19	growth	growth	NN
cord-018042-qt7055fw	91	20	hormone	hormone	NN
cord-018042-qt7055fw	91	21	(	(	-LRB-
cord-018042-qt7055fw	91	22	hGH	hGH	NNP
cord-018042-qt7055fw	91	23	)	)	-RRB-
cord-018042-qt7055fw	91	24	polyadenylation	polyadenylation	NN
cord-018042-qt7055fw	91	25	signal	signal	NN
cord-018042-qt7055fw	91	26	sequence	sequence	NN
cord-018042-qt7055fw	91	27	.	.	.
cord-018042-qt7055fw	92	1	This	this	DT
cord-018042-qt7055fw	92	2	transgene	transgene	NN
cord-018042-qt7055fw	92	3	construct	construct	NN
cord-018042-qt7055fw	92	4	was	be	VBD
cord-018042-qt7055fw	92	5	microinjected	microinjecte	VBN
cord-018042-qt7055fw	92	6	into	into	IN
cord-018042-qt7055fw	92	7	the	the	DT
cord-018042-qt7055fw	92	8	germ	germ	NN
cord-018042-qt7055fw	92	9	line	line	NN
cord-018042-qt7055fw	92	10	of	of	IN
cord-018042-qt7055fw	92	11	mice	mouse	NNS
cord-018042-qt7055fw	92	12	to	to	TO
cord-018042-qt7055fw	92	13	generate	generate	VB
cord-018042-qt7055fw	92	14	a	a	DT
cord-018042-qt7055fw	92	15	stable	stable	JJ
cord-018042-qt7055fw	92	16	transgenic	transgenic	JJ
cord-018042-qt7055fw	92	17	line	line	NN
cord-018042-qt7055fw	92	18	.	.	.
cord-018042-qt7055fw	93	1	The	the	DT
cord-018042-qt7055fw	93	2	presence	presence	NN
cord-018042-qt7055fw	93	3	of	of	IN
cord-018042-qt7055fw	93	4	CXCL10	CXCL10	NNP
cord-018042-qt7055fw	93	5	gene	gene	NN
cord-018042-qt7055fw	93	6	expression	expression	NN
cord-018042-qt7055fw	93	7	in	in	IN
cord-018042-qt7055fw	93	8	astrocytes	astrocyte	NNS
cord-018042-qt7055fw	93	9	(	(	-LRB-
cord-018042-qt7055fw	93	10	lower	low	JJR
cord-018042-qt7055fw	93	11	panel	panel	NN
cord-018042-qt7055fw	93	12	)	)	-RRB-
cord-018042-qt7055fw	93	13	was	be	VBD
cord-018042-qt7055fw	93	14	confirmed	confirm	VBN
cord-018042-qt7055fw	93	15	by	by	IN
cord-018042-qt7055fw	93	16	in	in	IN
cord-018042-qt7055fw	93	17	situ	situ	JJ
cord-018042-qt7055fw	93	18	hybridization	hybridization	NN
cord-018042-qt7055fw	93	19	for	for	IN
cord-018042-qt7055fw	93	20	CXCL10	CXCL10	NNP
cord-018042-qt7055fw	93	21	RNA	RNA	NNP
cord-018042-qt7055fw	93	22	combined	combine	VBN
cord-018042-qt7055fw	93	23	with	with	IN
cord-018042-qt7055fw	93	24	immunohistochemistry	immunohistochemistry	NN
cord-018042-qt7055fw	93	25	for	for	IN
cord-018042-qt7055fw	93	26	GFAP	GFAP	NNP
cord-018042-qt7055fw	93	27	protein	protein	NN
cord-018042-qt7055fw	93	28	.	.	.
cord-018042-qt7055fw	94	1	Note	note	VB
cord-018042-qt7055fw	94	2	that	that	IN
cord-018042-qt7055fw	94	3	some	some	DT
cord-018042-qt7055fw	94	4	CXCL10	CXCL10	NNP
cord-018042-qt7055fw	94	5	RNA	RNA	NNP
cord-018042-qt7055fw	94	6	positive	positive	JJ
cord-018042-qt7055fw	94	7	astrocytes	astrocyte	NNS
cord-018042-qt7055fw	94	8	(	(	-LRB-
cord-018042-qt7055fw	94	9	black	black	JJ
cord-018042-qt7055fw	94	10	arrows	arrow	NNS
cord-018042-qt7055fw	94	11	)	)	-RRB-
cord-018042-qt7055fw	94	12	extend	extend	VB
cord-018042-qt7055fw	94	13	processes	process	NNS
cord-018042-qt7055fw	94	14	(	(	-LRB-
cord-018042-qt7055fw	94	15	blue	blue	JJ
cord-018042-qt7055fw	94	16	arrows	arrow	NNS
cord-018042-qt7055fw	94	17	)	)	-RRB-
cord-018042-qt7055fw	94	18	to	to	IN
cord-018042-qt7055fw	94	19	a	a	DT
cord-018042-qt7055fw	94	20	blood	blood	NN
cord-018042-qt7055fw	94	21	vessel	vessel	NN
cord-018042-qt7055fw	94	22	(	(	-LRB-
cord-018042-qt7055fw	94	23	asterisk	asterisk	NN
cord-018042-qt7055fw	94	24	)	)	-RRB-
cord-018042-qt7055fw	94	25	that	that	WDT
cord-018042-qt7055fw	94	26	is	be	VBZ
cord-018042-qt7055fw	94	27	close	close	JJ
cord-018042-qt7055fw	94	28	by	by	IN
cord-018042-qt7055fw	95	1	(	(	-LRB-
cord-018042-qt7055fw	95	2	See	see	VB
cord-018042-qt7055fw	95	3	Color	color	NN
cord-018042-qt7055fw	95	4	Plates	plate	NNS
cord-018042-qt7055fw	95	5	)	)	-RRB-
cord-018042-qt7055fw	95	6	.	.	.
cord-018042-qt7055fw	96	1	were	be	VBD
cord-018042-qt7055fw	96	2	neutrophils	neutrophil	NNS
cord-018042-qt7055fw	96	3	and	and	CC
cord-018042-qt7055fw	96	4	macrophages	macrophage	NNS
cord-018042-qt7055fw	96	5	with	with	IN
cord-018042-qt7055fw	96	6	a	a	DT
cord-018042-qt7055fw	96	7	minority	minority	NN
cord-018042-qt7055fw	96	8	being	be	VBG
cord-018042-qt7055fw	96	9	represented	represent	VBN
cord-018042-qt7055fw	96	10	by	by	IN
cord-018042-qt7055fw	96	11	CD	CD	NNP
cord-018042-qt7055fw	96	12	+	+	CC
cord-018042-qt7055fw	96	13	Tcells	Tcells	NNP
cord-018042-qt7055fw	96	14	.	.	.
cord-018042-qt7055fw	97	1	These	these	DT
cord-018042-qt7055fw	97	2	observations	observation	NNS
cord-018042-qt7055fw	97	3	suggest	suggest	VBP
cord-018042-qt7055fw	97	4	that	that	IN
cord-018042-qt7055fw	97	5	constitutive	constitutive	JJ
cord-018042-qt7055fw	97	6	astrocyte	astrocyte	NN
cord-018042-qt7055fw	97	7	production	production	NN
cord-018042-qt7055fw	97	8	of	of	IN
cord-018042-qt7055fw	97	9	CXCL10	CXCL10	NNP
cord-018042-qt7055fw	97	10	in	in	IN
cord-018042-qt7055fw	97	11	the	the	DT
cord-018042-qt7055fw	97	12	CNS	CNS	NNP
cord-018042-qt7055fw	97	13	does	do	VBZ
cord-018042-qt7055fw	97	14	not	not	RB
cord-018042-qt7055fw	97	15	provide	provide	VB
cord-018042-qt7055fw	97	16	an	an	DT
cord-018042-qt7055fw	97	17	effective	effective	JJ
cord-018042-qt7055fw	97	18	signal	signal	NN
cord-018042-qt7055fw	97	19	for	for	IN
cord-018042-qt7055fw	97	20	the	the	DT
cord-018042-qt7055fw	97	21	recruitment	recruitment	NN
cord-018042-qt7055fw	97	22	of	of	IN
cord-018042-qt7055fw	97	23	T	T	NNP
cord-018042-qt7055fw	97	24	-	-	HYPH
cord-018042-qt7055fw	97	25	cells	cell	NNS
cord-018042-qt7055fw	97	26	from	from	IN
cord-018042-qt7055fw	97	27	the	the	DT
cord-018042-qt7055fw	97	28	periphery	periphery	NN
cord-018042-qt7055fw	97	29	.	.	.
cord-018042-qt7055fw	98	1	This	this	DT
cord-018042-qt7055fw	98	2	conclusion	conclusion	NN
cord-018042-qt7055fw	98	3	is	be	VBZ
cord-018042-qt7055fw	98	4	in	in	IN
cord-018042-qt7055fw	98	5	keeping	keep	VBG
cord-018042-qt7055fw	98	6	with	with	IN
cord-018042-qt7055fw	98	7	the	the	DT
cord-018042-qt7055fw	98	8	findings	finding	NNS
cord-018042-qt7055fw	98	9	from	from	IN
cord-018042-qt7055fw	98	10	more	more	JJR
cord-018042-qt7055fw	98	11	recent	recent	JJ
cord-018042-qt7055fw	98	12	reports	report	NNS
cord-018042-qt7055fw	98	13	that	that	WDT
cord-018042-qt7055fw	98	14	found	find	VBD
cord-018042-qt7055fw	98	15	that	that	IN
cord-018042-qt7055fw	98	16	mice	mouse	NNS
cord-018042-qt7055fw	98	17	deficient	deficient	JJ
cord-018042-qt7055fw	98	18	for	for	IN
cord-018042-qt7055fw	98	19	CXCL10	CXCL10	NNP
cord-018042-qt7055fw	98	20	exhibit	exhibit	VB
cord-018042-qt7055fw	98	21	similar	similar	JJ
cord-018042-qt7055fw	98	22	clinical	clinical	JJ
cord-018042-qt7055fw	98	23	and	and	CC
cord-018042-qt7055fw	98	24	pathological	pathological	JJ
cord-018042-qt7055fw	98	25	outcomes	outcome	NNS
cord-018042-qt7055fw	98	26	as	as	IN
cord-018042-qt7055fw	98	27	wild	wild	JJ
cord-018042-qt7055fw	98	28	type	type	NN
cord-018042-qt7055fw	98	29	controls	control	NNS
cord-018042-qt7055fw	98	30	for	for	IN
cord-018042-qt7055fw	98	31	experimental	experimental	JJ
cord-018042-qt7055fw	98	32	autoimmune	autoimmune	JJ
cord-018042-qt7055fw	98	33	encephalomyelitis	encephalomyelitis	NN
cord-018042-qt7055fw	98	34	(	(	-LRB-
cord-018042-qt7055fw	98	35	EAE	EAE	NNP
cord-018042-qt7055fw	98	36	-	-	HYPH
cord-018042-qt7055fw	98	37	a	a	DT
cord-018042-qt7055fw	98	38	CD4	CD4	NNP
cord-018042-qt7055fw	98	39	+	+	CC
cord-018042-qt7055fw	98	40	T	t	NN
cord-018042-qt7055fw	98	41	-	-	HYPH
cord-018042-qt7055fw	98	42	cell	cell	NN
cord-018042-qt7055fw	98	43	-	-	HYPH
cord-018042-qt7055fw	98	44	mediated	mediate	VBN
cord-018042-qt7055fw	98	45	disease	disease	NN
cord-018042-qt7055fw	98	46	)	)	-RRB-
cord-018042-qt7055fw	99	1	(	(	-LRB-
cord-018042-qt7055fw	99	2	Klein	Klein	NNP
cord-018042-qt7055fw	99	3	et	et	NNP
cord-018042-qt7055fw	99	4	al	al	NNP
cord-018042-qt7055fw	99	5	.	.	NNP
cord-018042-qt7055fw	99	6	,	,	,
cord-018042-qt7055fw	99	7	2004	2004	CD
cord-018042-qt7055fw	99	8	)	)	-RRB-
cord-018042-qt7055fw	99	9	as	as	RB
cord-018042-qt7055fw	99	10	well	well	RB
cord-018042-qt7055fw	99	11	as	as	IN
cord-018042-qt7055fw	99	12	murine	murine	JJ
cord-018042-qt7055fw	99	13	hepatitis	hepatitis	NN
cord-018042-qt7055fw	99	14	virus	virus	NN
cord-018042-qt7055fw	99	15	encephalitis	encephalitis	JJ
cord-018042-qt7055fw	99	16	(	(	-LRB-
cord-018042-qt7055fw	99	17	Stiles	Stiles	NNP
cord-018042-qt7055fw	99	18	et	et	NNP
cord-018042-qt7055fw	99	19	al	al	NNP
cord-018042-qt7055fw	99	20	.	.	NNP
cord-018042-qt7055fw	99	21	,	,	,
cord-018042-qt7055fw	99	22	2006	2006	CD
cord-018042-qt7055fw	99	23	)	)	-RRB-
cord-018042-qt7055fw	99	24	.	.	.
cord-018042-qt7055fw	100	1	The	the	DT
cord-018042-qt7055fw	100	2	finding	finding	NN
cord-018042-qt7055fw	100	3	that	that	IN
cord-018042-qt7055fw	100	4	neutrophils	neutrophil	NNS
cord-018042-qt7055fw	100	5	were	be	VBD
cord-018042-qt7055fw	100	6	preferentially	preferentially	RB
cord-018042-qt7055fw	100	7	recruited	recruit	VBN
cord-018042-qt7055fw	100	8	to	to	IN
cord-018042-qt7055fw	100	9	the	the	DT
cord-018042-qt7055fw	100	10	CNS	CNS	NNP
cord-018042-qt7055fw	100	11	of	of	IN
cord-018042-qt7055fw	100	12	the	the	DT
cord-018042-qt7055fw	100	13	GFAP	GFAP	NNP
cord-018042-qt7055fw	100	14	-	-	HYPH
cord-018042-qt7055fw	100	15	CXCL10	cxcl10	CD
cord-018042-qt7055fw	100	16	transgenic	transgenic	JJ
cord-018042-qt7055fw	100	17	mice	mouse	NNS
cord-018042-qt7055fw	100	18	was	be	VBD
cord-018042-qt7055fw	100	19	unexpected	unexpected	JJ
cord-018042-qt7055fw	100	20	since	since	IN
cord-018042-qt7055fw	100	21	these	these	DT
cord-018042-qt7055fw	100	22	cells	cell	NNS
cord-018042-qt7055fw	100	23	were	be	VBD
cord-018042-qt7055fw	100	24	not	not	RB
cord-018042-qt7055fw	100	25	known	know	VBN
cord-018042-qt7055fw	100	26	to	to	TO
cord-018042-qt7055fw	100	27	have	have	VB
cord-018042-qt7055fw	100	28	CXCR3	CXCR3	VBN
cord-018042-qt7055fw	100	29	.	.	.
cord-018042-qt7055fw	101	1	This	this	DT
cord-018042-qt7055fw	101	2	point	point	NN
cord-018042-qt7055fw	101	3	was	be	VBD
cord-018042-qt7055fw	101	4	confirmed	confirm	VBN
cord-018042-qt7055fw	101	5	by	by	IN
cord-018042-qt7055fw	101	6	the	the	DT
cord-018042-qt7055fw	101	7	studies	study	NNS
cord-018042-qt7055fw	101	8	of	of	IN
cord-018042-qt7055fw	101	9	Boztug	Boztug	NNP
cord-018042-qt7055fw	101	10	et	et	NNP
cord-018042-qt7055fw	101	11	al	al	NNP
cord-018042-qt7055fw	101	12	.	.	.
cord-018042-qt7055fw	102	1	(	(	-LRB-
cord-018042-qt7055fw	102	2	2002	2002	CD
cord-018042-qt7055fw	102	3	)	)	-RRB-
cord-018042-qt7055fw	102	4	who	who	WP
cord-018042-qt7055fw	102	5	used	use	VBD
cord-018042-qt7055fw	102	6	fluorescence	fluorescence	NN
cord-018042-qt7055fw	102	7	activated	activate	VBN
cord-018042-qt7055fw	102	8	cell	cell	NN
cord-018042-qt7055fw	102	9	sorting	sorting	NN
cord-018042-qt7055fw	102	10	analysis	analysis	NN
cord-018042-qt7055fw	102	11	to	to	TO
cord-018042-qt7055fw	102	12	show	show	VB
cord-018042-qt7055fw	102	13	that	that	IN
cord-018042-qt7055fw	102	14	the	the	DT
cord-018042-qt7055fw	102	15	neutrophil	neutrophil	NN
cord-018042-qt7055fw	102	16	population	population	NN
cord-018042-qt7055fw	102	17	present	present	JJ
cord-018042-qt7055fw	102	18	in	in	IN
cord-018042-qt7055fw	102	19	the	the	DT
cord-018042-qt7055fw	102	20	CNS	CNS	NNP
cord-018042-qt7055fw	102	21	of	of	IN
cord-018042-qt7055fw	102	22	the	the	DT
cord-018042-qt7055fw	102	23	GFAP	GFAP	NNP
cord-018042-qt7055fw	102	24	-	-	HYPH
cord-018042-qt7055fw	102	25	CXCL10	cxcl10	CD
cord-018042-qt7055fw	102	26	transgenic	transgenic	JJ
cord-018042-qt7055fw	102	27	mice	mouse	NNS
cord-018042-qt7055fw	102	28	were	be	VBD
cord-018042-qt7055fw	102	29	CXCR3	CXCR3	VBN
cord-018042-qt7055fw	102	30	negative	negative	JJ
cord-018042-qt7055fw	102	31	.	.	.
cord-018042-qt7055fw	103	1	Moreover	moreover	RB
cord-018042-qt7055fw	103	2	,	,	,
cord-018042-qt7055fw	103	3	the	the	DT
cord-018042-qt7055fw	103	4	results	result	NNS
cord-018042-qt7055fw	103	5	of	of	IN
cord-018042-qt7055fw	103	6	a	a	DT
cord-018042-qt7055fw	103	7	survey	survey	NN
cord-018042-qt7055fw	103	8	of	of	IN
cord-018042-qt7055fw	103	9	the	the	DT
cord-018042-qt7055fw	103	10	cerebral	cerebral	JJ
cord-018042-qt7055fw	103	11	expression	expression	NN
cord-018042-qt7055fw	103	12	of	of	IN
cord-018042-qt7055fw	103	13	a	a	DT
cord-018042-qt7055fw	103	14	large	large	JJ
cord-018042-qt7055fw	103	15	number	number	NN
cord-018042-qt7055fw	103	16	of	of	IN
cord-018042-qt7055fw	103	17	other	other	JJ
cord-018042-qt7055fw	103	18	chemokines	chemokine	NNS
cord-018042-qt7055fw	103	19	including	include	VBG
cord-018042-qt7055fw	103	20	ELR	ELR	NNP
cord-018042-qt7055fw	103	21	-	-	HYPH
cord-018042-qt7055fw	103	22	CXC	CXC	NNP
cord-018042-qt7055fw	103	23	chemokines	chemokine	NNS
cord-018042-qt7055fw	103	24	known	know	VBN
cord-018042-qt7055fw	103	25	to	to	TO
cord-018042-qt7055fw	103	26	have	have	VB
cord-018042-qt7055fw	103	27	neutrophil	neutrophil	NN
cord-018042-qt7055fw	103	28	chemoattractant	chemoattractant	NN
cord-018042-qt7055fw	103	29	properties	property	NNS
cord-018042-qt7055fw	103	30	proved	prove	VBD
cord-018042-qt7055fw	103	31	unremarkable	unremarkable	JJ
cord-018042-qt7055fw	103	32	.	.	.
cord-018042-qt7055fw	104	1	Therefore	therefore	RB
cord-018042-qt7055fw	104	2	,	,	,
cord-018042-qt7055fw	104	3	the	the	DT
cord-018042-qt7055fw	104	4	basis	basis	NN
cord-018042-qt7055fw	104	5	for	for	IN
cord-018042-qt7055fw	104	6	the	the	DT
cord-018042-qt7055fw	104	7	preferential	preferential	JJ
cord-018042-qt7055fw	104	8	accumulation	accumulation	NN
cord-018042-qt7055fw	104	9	of	of	IN
cord-018042-qt7055fw	104	10	neutrophils	neutrophil	NNS
cord-018042-qt7055fw	104	11	in	in	IN
cord-018042-qt7055fw	104	12	the	the	DT
cord-018042-qt7055fw	104	13	brain	brain	NN
cord-018042-qt7055fw	104	14	of	of	IN
cord-018042-qt7055fw	104	15	the	the	DT
cord-018042-qt7055fw	104	16	transgenic	transgenic	JJ
cord-018042-qt7055fw	104	17	mice	mouse	NNS
cord-018042-qt7055fw	104	18	is	be	VBZ
cord-018042-qt7055fw	104	19	unknown	unknown	JJ
cord-018042-qt7055fw	104	20	.	.	.
cord-018042-qt7055fw	105	1	In	in	IN
cord-018042-qt7055fw	105	2	all	all	DT
cord-018042-qt7055fw	105	3	,	,	,
cord-018042-qt7055fw	105	4	these	these	DT
cord-018042-qt7055fw	105	5	findings	finding	NNS
cord-018042-qt7055fw	105	6	argue	argue	VBP
cord-018042-qt7055fw	105	7	for	for	IN
cord-018042-qt7055fw	105	8	a	a	DT
cord-018042-qt7055fw	105	9	CXCR3-independent	CXCR3-independent	NNP
cord-018042-qt7055fw	105	10	chemoattractant	chemoattractant	NN
cord-018042-qt7055fw	105	11	mechanism	mechanism	NN
cord-018042-qt7055fw	105	12	mediated	mediate	VBN
cord-018042-qt7055fw	105	13	by	by	IN
cord-018042-qt7055fw	105	14	CXCL10	CXCL10	NNP
cord-018042-qt7055fw	105	15	for	for	IN
cord-018042-qt7055fw	105	16	the	the	DT
cord-018042-qt7055fw	105	17	recruitment	recruitment	NN
cord-018042-qt7055fw	105	18	of	of	IN
cord-018042-qt7055fw	105	19	neutrophils	neutrophil	NNS
cord-018042-qt7055fw	105	20	to	to	IN
cord-018042-qt7055fw	105	21	the	the	DT
cord-018042-qt7055fw	105	22	brain	brain	NN
cord-018042-qt7055fw	105	23	.	.	.
cord-018042-qt7055fw	106	1	It	-PRON-	PRP
cord-018042-qt7055fw	106	2	is	be	VBZ
cord-018042-qt7055fw	106	3	interesting	interesting	JJ
cord-018042-qt7055fw	106	4	to	to	TO
cord-018042-qt7055fw	106	5	note	note	VB
cord-018042-qt7055fw	106	6	that	that	IN
cord-018042-qt7055fw	106	7	an	an	DT
cord-018042-qt7055fw	106	8	alternative	alternative	JJ
cord-018042-qt7055fw	106	9	receptor	receptor	NN
cord-018042-qt7055fw	106	10	for	for	IN
cord-018042-qt7055fw	106	11	CXCL10	CXCL10	NNP
cord-018042-qt7055fw	106	12	has	have	VBZ
cord-018042-qt7055fw	106	13	been	be	VBN
cord-018042-qt7055fw	106	14	reported	report	VBN
cord-018042-qt7055fw	106	15	on	on	IN
cord-018042-qt7055fw	106	16	endothelial	endothelial	JJ
cord-018042-qt7055fw	106	17	and	and	CC
cord-018042-qt7055fw	106	18	epithelial	epithelial	JJ
cord-018042-qt7055fw	106	19	cells	cell	NNS
cord-018042-qt7055fw	106	20	(	(	-LRB-
cord-018042-qt7055fw	106	21	Soejima	Soejima	NNP
cord-018042-qt7055fw	106	22	and	and	CC
cord-018042-qt7055fw	106	23	Rollins	Rollins	NNP
cord-018042-qt7055fw	106	24	,	,	,
cord-018042-qt7055fw	106	25	2001	2001	CD
cord-018042-qt7055fw	106	26	)	)	-RRB-
cord-018042-qt7055fw	106	27	.	.	.
cord-018042-qt7055fw	107	1	However	however	RB
cord-018042-qt7055fw	107	2	,	,	,
cord-018042-qt7055fw	107	3	the	the	DT
cord-018042-qt7055fw	107	4	identity	identity	NN
cord-018042-qt7055fw	107	5	of	of	IN
cord-018042-qt7055fw	107	6	this	this	DT
cord-018042-qt7055fw	107	7	novel	novel	NN
cord-018042-qt7055fw	107	8	CXCL10	CXCL10	NNP
cord-018042-qt7055fw	107	9	binding	bind	VBG
cord-018042-qt7055fw	107	10	moiety	moiety	NN
cord-018042-qt7055fw	107	11	and	and	CC
cord-018042-qt7055fw	107	12	its	-PRON-	PRP$
cord-018042-qt7055fw	107	13	functional	functional	JJ
cord-018042-qt7055fw	107	14	signature	signature	NN
cord-018042-qt7055fw	107	15	is	be	VBZ
cord-018042-qt7055fw	107	16	currently	currently	RB
cord-018042-qt7055fw	107	17	unknown	unknown	JJ
cord-018042-qt7055fw	107	18	.	.	.
cord-018042-qt7055fw	108	1	Of	of	IN
cord-018042-qt7055fw	108	2	further	further	JJ
cord-018042-qt7055fw	108	3	note	note	NN
cord-018042-qt7055fw	108	4	in	in	IN
cord-018042-qt7055fw	108	5	these	these	DT
cord-018042-qt7055fw	108	6	GFAP	GFAP	NNP
cord-018042-qt7055fw	108	7	-	-	HYPH
cord-018042-qt7055fw	108	8	CXCL10	cxcl10	CD
cord-018042-qt7055fw	108	9	transgenic	transgenic	JJ
cord-018042-qt7055fw	108	10	mice	mouse	NNS
cord-018042-qt7055fw	108	11	was	be	VBD
cord-018042-qt7055fw	108	12	the	the	DT
cord-018042-qt7055fw	108	13	lack	lack	NN
cord-018042-qt7055fw	108	14	of	of	IN
cord-018042-qt7055fw	108	15	any	any	DT
cord-018042-qt7055fw	108	16	gliosis	gliosis	NN
cord-018042-qt7055fw	108	17	or	or	CC
cord-018042-qt7055fw	108	18	degenerative	degenerative	JJ
cord-018042-qt7055fw	108	19	features	feature	NNS
cord-018042-qt7055fw	108	20	that	that	WDT
cord-018042-qt7055fw	108	21	would	would	MD
cord-018042-qt7055fw	108	22	be	be	VB
cord-018042-qt7055fw	108	23	expected	expect	VBN
cord-018042-qt7055fw	108	24	if	if	IN
cord-018042-qt7055fw	108	25	there	there	EX
cord-018042-qt7055fw	108	26	existed	exist	VBD
cord-018042-qt7055fw	108	27	a	a	DT
cord-018042-qt7055fw	108	28	destructive	destructive	JJ
cord-018042-qt7055fw	108	29	immunoinflammatory	immunoinflammatory	NN
cord-018042-qt7055fw	108	30	response	response	NN
cord-018042-qt7055fw	108	31	in	in	IN
cord-018042-qt7055fw	108	32	the	the	DT
cord-018042-qt7055fw	108	33	CNS	CNS	NNP
cord-018042-qt7055fw	108	34	.	.	.
cord-018042-qt7055fw	109	1	So	so	RB
cord-018042-qt7055fw	109	2	while	while	IN
cord-018042-qt7055fw	109	3	constitutive	constitutive	JJ
cord-018042-qt7055fw	109	4	,	,	,
cord-018042-qt7055fw	109	5	astrocyte	astrocyte	RB
cord-018042-qt7055fw	109	6	-	-	HYPH
cord-018042-qt7055fw	109	7	targeted	target	VBN
cord-018042-qt7055fw	109	8	production	production	NN
cord-018042-qt7055fw	109	9	of	of	IN
cord-018042-qt7055fw	109	10	CXCL10	CXCL10	NNP
cord-018042-qt7055fw	109	11	can	can	MD
cord-018042-qt7055fw	109	12	promote	promote	VB
cord-018042-qt7055fw	109	13	the	the	DT
cord-018042-qt7055fw	109	14	recruitment	recruitment	NN
cord-018042-qt7055fw	109	15	of	of	IN
cord-018042-qt7055fw	109	16	leukocytes	leukocyte	NNS
cord-018042-qt7055fw	109	17	to	to	IN
cord-018042-qt7055fw	109	18	the	the	DT
cord-018042-qt7055fw	109	19	CNS	CNS	NNP
cord-018042-qt7055fw	109	20	,	,	,
cord-018042-qt7055fw	109	21	this	this	DT
cord-018042-qt7055fw	109	22	chemokine	chemokine	NN
cord-018042-qt7055fw	109	23	lacks	lack	VBZ
cord-018042-qt7055fw	109	24	the	the	DT
cord-018042-qt7055fw	109	25	ability	ability	NN
cord-018042-qt7055fw	109	26	to	to	TO
cord-018042-qt7055fw	109	27	further	further	JJ
cord-018042-qt7055fw	109	28	influence	influence	VB
cord-018042-qt7055fw	109	29	these	these	DT
cord-018042-qt7055fw	109	30	cells	cell	NNS
cord-018042-qt7055fw	109	31	,	,	,
cord-018042-qt7055fw	109	32	in	in	IN
cord-018042-qt7055fw	109	33	particular	particular	JJ
cord-018042-qt7055fw	109	34	,	,	,
cord-018042-qt7055fw	109	35	to	to	TO
cord-018042-qt7055fw	109	36	drive	drive	VB
cord-018042-qt7055fw	109	37	a	a	DT
cord-018042-qt7055fw	109	38	functional	functional	JJ
cord-018042-qt7055fw	109	39	immune	immune	JJ
cord-018042-qt7055fw	109	40	response	response	NN
cord-018042-qt7055fw	109	41	.	.	.
cord-018042-qt7055fw	110	1	Moreover	moreover	RB
cord-018042-qt7055fw	110	2	,	,	,
cord-018042-qt7055fw	110	3	although	although	IN
cord-018042-qt7055fw	110	4	there	there	EX
cord-018042-qt7055fw	110	5	are	be	VBP
cord-018042-qt7055fw	110	6	reports	report	NNS
cord-018042-qt7055fw	110	7	that	that	IN
cord-018042-qt7055fw	110	8	a	a	DT
cord-018042-qt7055fw	110	9	functional	functional	JJ
cord-018042-qt7055fw	110	10	CXCR3	cxcr3	NN
cord-018042-qt7055fw	110	11	exists	exist	VBZ
cord-018042-qt7055fw	110	12	on	on	IN
cord-018042-qt7055fw	110	13	neurons	neuron	NNS
cord-018042-qt7055fw	110	14	(	(	-LRB-
cord-018042-qt7055fw	110	15	Nelson	Nelson	NNP
cord-018042-qt7055fw	110	16	and	and	CC
cord-018042-qt7055fw	110	17	Gruol	Gruol	NNP
cord-018042-qt7055fw	110	18	,	,	,
cord-018042-qt7055fw	110	19	2004	2004	CD
cord-018042-qt7055fw	110	20	)	)	-RRB-
cord-018042-qt7055fw	110	21	and	and	CC
cord-018042-qt7055fw	110	22	microglia	microglia	NNP
cord-018042-qt7055fw	110	23	(	(	-LRB-
cord-018042-qt7055fw	110	24	Rappert	Rappert	NNP
cord-018042-qt7055fw	110	25	et	et	NNP
cord-018042-qt7055fw	110	26	al	al	NNP
cord-018042-qt7055fw	110	27	.	.	NNP
cord-018042-qt7055fw	110	28	,	,	,
cord-018042-qt7055fw	110	29	2004	2004	CD
cord-018042-qt7055fw	110	30	)	)	-RRB-
cord-018042-qt7055fw	110	31	in	in	IN
cord-018042-qt7055fw	110	32	the	the	DT
cord-018042-qt7055fw	110	33	rodent	rodent	NN
cord-018042-qt7055fw	110	34	CNS	CNS	NNP
cord-018042-qt7055fw	110	35	,	,	,
cord-018042-qt7055fw	110	36	there	there	EX
cord-018042-qt7055fw	110	37	would	would	MD
cord-018042-qt7055fw	110	38	seem	seem	VB
cord-018042-qt7055fw	110	39	to	to	TO
cord-018042-qt7055fw	110	40	be	be	VB
cord-018042-qt7055fw	110	41	little	little	JJ
cord-018042-qt7055fw	110	42	effect	effect	NN
cord-018042-qt7055fw	110	43	of	of	IN
cord-018042-qt7055fw	110	44	CXCL10	CXCL10	NNP
cord-018042-qt7055fw	110	45	on	on	IN
cord-018042-qt7055fw	110	46	these	these	DT
cord-018042-qt7055fw	110	47	cells	cell	NNS
cord-018042-qt7055fw	110	48	in	in	IN
cord-018042-qt7055fw	110	49	this	this	DT
cord-018042-qt7055fw	110	50	transgenic	transgenic	JJ
cord-018042-qt7055fw	110	51	model	model	NN
cord-018042-qt7055fw	110	52	.	.	.
cord-018042-qt7055fw	111	1	A	a	DT
cord-018042-qt7055fw	111	2	possible	possible	JJ
cord-018042-qt7055fw	111	3	explanation	explanation	NN
cord-018042-qt7055fw	111	4	for	for	IN
cord-018042-qt7055fw	111	5	this	this	DT
cord-018042-qt7055fw	111	6	lack	lack	NN
cord-018042-qt7055fw	111	7	of	of	IN
cord-018042-qt7055fw	111	8	effect	effect	NN
cord-018042-qt7055fw	111	9	of	of	IN
cord-018042-qt7055fw	111	10	CXCL10	CXCL10	NNP
cord-018042-qt7055fw	111	11	is	be	VBZ
cord-018042-qt7055fw	111	12	that	that	IN
cord-018042-qt7055fw	111	13	there	there	EX
cord-018042-qt7055fw	111	14	is	be	VBZ
cord-018042-qt7055fw	111	15	desensitization	desensitization	NN
cord-018042-qt7055fw	111	16	to	to	IN
cord-018042-qt7055fw	111	17	the	the	DT
cord-018042-qt7055fw	111	18	chemokine	chemokine	NN
cord-018042-qt7055fw	111	19	through	through	IN
cord-018042-qt7055fw	111	20	CXCR3	cxcr3	XX
cord-018042-qt7055fw	111	21	downregulation	downregulation	NN
cord-018042-qt7055fw	111	22	.	.	.
cord-018042-qt7055fw	112	1	In	in	IN
cord-018042-qt7055fw	112	2	support	support	NN
cord-018042-qt7055fw	112	3	of	of	IN
cord-018042-qt7055fw	112	4	this	this	DT
cord-018042-qt7055fw	112	5	idea	idea	NN
cord-018042-qt7055fw	112	6	,	,	,
cord-018042-qt7055fw	112	7	hippocampal	hippocampal	JJ
cord-018042-qt7055fw	112	8	slices	slice	NNS
cord-018042-qt7055fw	112	9	from	from	IN
cord-018042-qt7055fw	112	10	wild	wild	JJ
cord-018042-qt7055fw	112	11	type	type	NN
cord-018042-qt7055fw	112	12	but	but	CC
cord-018042-qt7055fw	112	13	not	not	RB
cord-018042-qt7055fw	112	14	GFAP	GFAP	NNP
cord-018042-qt7055fw	112	15	-	-	HYPH
cord-018042-qt7055fw	112	16	CXCL10	cxcl10	CD
cord-018042-qt7055fw	112	17	transgenic	transgenic	JJ
cord-018042-qt7055fw	112	18	mice	mouse	NNS
cord-018042-qt7055fw	112	19	in	in	IN
cord-018042-qt7055fw	112	20	response	response	NN
cord-018042-qt7055fw	112	21	to	to	IN
cord-018042-qt7055fw	112	22	acute	acute	JJ
cord-018042-qt7055fw	112	23	exposure	exposure	NN
cord-018042-qt7055fw	112	24	to	to	IN
cord-018042-qt7055fw	112	25	recombinant	recombinant	JJ
cord-018042-qt7055fw	112	26	CXCL10	CXCL10	NNP
cord-018042-qt7055fw	112	27	protein	protein	NN
cord-018042-qt7055fw	112	28	were	be	VBD
cord-018042-qt7055fw	112	29	shown	show	VBN
cord-018042-qt7055fw	112	30	to	to	TO
cord-018042-qt7055fw	112	31	exhibit	exhibit	VB
cord-018042-qt7055fw	112	32	altered	alter	VBN
cord-018042-qt7055fw	112	33	synaptic	synaptic	JJ
cord-018042-qt7055fw	112	34	plasticity	plasticity	NN
cord-018042-qt7055fw	112	35	that	that	WDT
cord-018042-qt7055fw	112	36	was	be	VBD
cord-018042-qt7055fw	112	37	CXCR3dependent	CXCR3dependent	NNP
cord-018042-qt7055fw	113	1	(	(	-LRB-
cord-018042-qt7055fw	113	2	Vlkolinsky	Vlkolinsky	NNP
cord-018042-qt7055fw	113	3	et	et	NNP
cord-018042-qt7055fw	113	4	al	al	NNP
cord-018042-qt7055fw	113	5	.	.	NNP
cord-018042-qt7055fw	113	6	,	,	,
cord-018042-qt7055fw	113	7	2004	2004	CD
cord-018042-qt7055fw	113	8	)	)	-RRB-
cord-018042-qt7055fw	113	9	.	.	.
cord-018042-qt7055fw	114	1	Interestingly	interestingly	RB
cord-018042-qt7055fw	114	2	,	,	,
cord-018042-qt7055fw	114	3	the	the	DT
cord-018042-qt7055fw	114	4	role	role	NN
cord-018042-qt7055fw	114	5	of	of	IN
cord-018042-qt7055fw	114	6	CXCL10	CXCL10	NNP
cord-018042-qt7055fw	114	7	as	as	IN
cord-018042-qt7055fw	114	8	an	an	DT
cord-018042-qt7055fw	114	9	effective	effective	JJ
cord-018042-qt7055fw	114	10	T	t	NN
cord-018042-qt7055fw	114	11	-	-	HYPH
cord-018042-qt7055fw	114	12	cell	cell	NN
cord-018042-qt7055fw	114	13	chemoattractant	chemoattractant	NN
cord-018042-qt7055fw	114	14	may	may	MD
cord-018042-qt7055fw	114	15	depend	depend	VB
cord-018042-qt7055fw	114	16	on	on	IN
cord-018042-qt7055fw	114	17	the	the	DT
cord-018042-qt7055fw	114	18	tissue	tissue	NN
cord-018042-qt7055fw	114	19	in	in	IN
cord-018042-qt7055fw	114	20	which	which	WDT
cord-018042-qt7055fw	114	21	the	the	DT
cord-018042-qt7055fw	114	22	chemokine	chemokine	NN
cord-018042-qt7055fw	114	23	is	be	VBZ
cord-018042-qt7055fw	114	24	produced	produce	VBN
cord-018042-qt7055fw	114	25	.	.	.
cord-018042-qt7055fw	115	1	In	in	IN
cord-018042-qt7055fw	115	2	contrast	contrast	NN
cord-018042-qt7055fw	115	3	to	to	IN
cord-018042-qt7055fw	115	4	the	the	DT
cord-018042-qt7055fw	115	5	CNS	CNS	NNP
cord-018042-qt7055fw	115	6	,	,	,
cord-018042-qt7055fw	115	7	transgenic	transgenic	JJ
cord-018042-qt7055fw	115	8	production	production	NN
cord-018042-qt7055fw	115	9	of	of	IN
cord-018042-qt7055fw	115	10	CXCL10	CXCL10	NNP
cord-018042-qt7055fw	115	11	targeted	target	VBN
cord-018042-qt7055fw	115	12	to	to	IN
cord-018042-qt7055fw	115	13	the	the	DT
cord-018042-qt7055fw	115	14	beta	beta	NN
cord-018042-qt7055fw	115	15	cells	cell	NNS
cord-018042-qt7055fw	115	16	of	of	IN
cord-018042-qt7055fw	115	17	the	the	DT
cord-018042-qt7055fw	115	18	islets	islet	NNS
cord-018042-qt7055fw	115	19	of	of	IN
cord-018042-qt7055fw	115	20	Langerhans	Langerhans	NNP
cord-018042-qt7055fw	115	21	induced	induce	VBD
cord-018042-qt7055fw	115	22	spontaneous	spontaneous	JJ
cord-018042-qt7055fw	115	23	infiltration	infiltration	NN
cord-018042-qt7055fw	115	24	of	of	IN
cord-018042-qt7055fw	115	25	large	large	JJ
cord-018042-qt7055fw	115	26	numbers	number	NNS
cord-018042-qt7055fw	115	27	of	of	IN
cord-018042-qt7055fw	115	28	CD4	CD4	NNP
cord-018042-qt7055fw	115	29	+	+	CC
cord-018042-qt7055fw	115	30	and	and	CC
cord-018042-qt7055fw	115	31	CD8	CD8	NNP
cord-018042-qt7055fw	115	32	+	+	CC
cord-018042-qt7055fw	115	33	T	T	NNP
cord-018042-qt7055fw	115	34	-	-	HYPH
cord-018042-qt7055fw	115	35	cells	cell	NNS
cord-018042-qt7055fw	115	36	around	around	IN
cord-018042-qt7055fw	115	37	the	the	DT
cord-018042-qt7055fw	115	38	islets	islet	NNS
cord-018042-qt7055fw	116	1	(	(	-LRB-
cord-018042-qt7055fw	116	2	Rhode	Rhode	NNP
cord-018042-qt7055fw	116	3	et	et	NNP
cord-018042-qt7055fw	116	4	al	al	NNP
cord-018042-qt7055fw	116	5	.	.	NNP
cord-018042-qt7055fw	116	6	,	,	,
cord-018042-qt7055fw	116	7	2005	2005	CD
cord-018042-qt7055fw	116	8	)	)	-RRB-
cord-018042-qt7055fw	116	9	.	.	.
cord-018042-qt7055fw	117	1	Moreover	moreover	RB
cord-018042-qt7055fw	117	2	,	,	,
cord-018042-qt7055fw	117	3	islet	islet	NN
cord-018042-qt7055fw	117	4	CXCL10	cxcl10	CD
cord-018042-qt7055fw	117	5	production	production	NN
cord-018042-qt7055fw	117	6	markedly	markedly	RB
cord-018042-qt7055fw	117	7	accelerated	accelerate	VBD
cord-018042-qt7055fw	117	8	a	a	DT
cord-018042-qt7055fw	117	9	stimulus	stimulus	NN
cord-018042-qt7055fw	117	10	-	-	HYPH
cord-018042-qt7055fw	117	11	evoked	evoke	VBN
cord-018042-qt7055fw	117	12	autoimmune	autoimmune	JJ
cord-018042-qt7055fw	117	13	process	process	NN
cord-018042-qt7055fw	117	14	by	by	IN
cord-018042-qt7055fw	117	15	enhancing	enhance	VBG
cord-018042-qt7055fw	117	16	the	the	DT
cord-018042-qt7055fw	117	17	migration	migration	NN
cord-018042-qt7055fw	117	18	of	of	IN
cord-018042-qt7055fw	117	19	antigen	antigen	NN
cord-018042-qt7055fw	117	20	-	-	HYPH
cord-018042-qt7055fw	117	21	specific	specific	JJ
cord-018042-qt7055fw	117	22	T	t	NN
cord-018042-qt7055fw	117	23	-	-	HYPH
cord-018042-qt7055fw	117	24	cells	cell	NNS
cord-018042-qt7055fw	117	25	to	to	IN
cord-018042-qt7055fw	117	26	the	the	DT
cord-018042-qt7055fw	117	27	islets	islet	NNS
cord-018042-qt7055fw	117	28	resulting	result	VBG
cord-018042-qt7055fw	117	29	in	in	IN
cord-018042-qt7055fw	117	30	the	the	DT
cord-018042-qt7055fw	117	31	development	development	NN
cord-018042-qt7055fw	117	32	type	type	NN
cord-018042-qt7055fw	117	33	I	-PRON-	PRP
cord-018042-qt7055fw	117	34	diabetes	diabete	VBZ
cord-018042-qt7055fw	117	35	.	.	.
cord-018042-qt7055fw	118	1	The	the	DT
cord-018042-qt7055fw	118	2	chemokine	chemokine	NN
cord-018042-qt7055fw	118	3	CCL2	CCL2	NNP
cord-018042-qt7055fw	118	4	(	(	-LRB-
cord-018042-qt7055fw	118	5	also	also	RB
cord-018042-qt7055fw	118	6	known	know	VBN
cord-018042-qt7055fw	118	7	as	as	IN
cord-018042-qt7055fw	118	8	MCP-1	MCP-1	NNP
cord-018042-qt7055fw	118	9	and	and	CC
cord-018042-qt7055fw	118	10	JE	JE	NNP
cord-018042-qt7055fw	118	11	)	)	-RRB-
cord-018042-qt7055fw	118	12	was	be	VBD
cord-018042-qt7055fw	118	13	first	first	RB
cord-018042-qt7055fw	118	14	identified	identify	VBN
cord-018042-qt7055fw	118	15	as	as	IN
cord-018042-qt7055fw	118	16	a	a	DT
cord-018042-qt7055fw	118	17	monocyte	monocyte	NNP
cord-018042-qt7055fw	118	18	attracting	attract	VBG
cord-018042-qt7055fw	118	19	chemokine	chemokine	NN
cord-018042-qt7055fw	118	20	(	(	-LRB-
cord-018042-qt7055fw	118	21	Rollins	Rollins	NNP
cord-018042-qt7055fw	118	22	,	,	,
cord-018042-qt7055fw	118	23	1991	1991	CD
cord-018042-qt7055fw	118	24	;	;	:
cord-018042-qt7055fw	118	25	Rollins	Rollins	NNP
cord-018042-qt7055fw	118	26	et	et	NNP
cord-018042-qt7055fw	118	27	al	al	NNP
cord-018042-qt7055fw	118	28	.	.	NNP
cord-018042-qt7055fw	118	29	,	,	,
cord-018042-qt7055fw	118	30	1991	1991	CD
cord-018042-qt7055fw	118	31	)	)	-RRB-
cord-018042-qt7055fw	118	32	but	but	CC
cord-018042-qt7055fw	118	33	also	also	RB
cord-018042-qt7055fw	118	34	has	have	VBZ
cord-018042-qt7055fw	118	35	been	be	VBN
cord-018042-qt7055fw	118	36	shown	show	VBN
cord-018042-qt7055fw	118	37	to	to	TO
cord-018042-qt7055fw	118	38	attract	attract	VB
cord-018042-qt7055fw	118	39	a	a	DT
cord-018042-qt7055fw	118	40	wide	wide	JJ
cord-018042-qt7055fw	118	41	variety	variety	NN
cord-018042-qt7055fw	118	42	of	of	IN
cord-018042-qt7055fw	118	43	other	other	JJ
cord-018042-qt7055fw	118	44	leukocytes	leukocyte	NNS
cord-018042-qt7055fw	118	45	,	,	,
cord-018042-qt7055fw	118	46	including	include	VBG
cord-018042-qt7055fw	118	47	,	,	,
cord-018042-qt7055fw	118	48	activated	activate	VBN
cord-018042-qt7055fw	118	49	T	t	NN
cord-018042-qt7055fw	118	50	-	-	HYPH
cord-018042-qt7055fw	118	51	cells	cell	NNS
cord-018042-qt7055fw	118	52	,	,	,
cord-018042-qt7055fw	118	53	dendritic	dendritic	JJ
cord-018042-qt7055fw	118	54	cells	cell	NNS
cord-018042-qt7055fw	118	55	,	,	,
cord-018042-qt7055fw	118	56	mast	mast	NN
cord-018042-qt7055fw	118	57	cells	cell	NNS
cord-018042-qt7055fw	118	58	and	and	CC
cord-018042-qt7055fw	118	59	basophils	basophil	NNS
cord-018042-qt7055fw	118	60	(	(	-LRB-
cord-018042-qt7055fw	118	61	Taub	Taub	NNP
cord-018042-qt7055fw	118	62	et	et	NNP
cord-018042-qt7055fw	118	63	al	al	NNP
cord-018042-qt7055fw	118	64	.	.	NNP
cord-018042-qt7055fw	118	65	,	,	,
cord-018042-qt7055fw	118	66	1996b	1996b	CD
cord-018042-qt7055fw	118	67	;	;	:
cord-018042-qt7055fw	118	68	Gunn	Gunn	NNP
cord-018042-qt7055fw	118	69	et	et	NNP
cord-018042-qt7055fw	118	70	al	al	NNP
cord-018042-qt7055fw	118	71	.	.	NNP
cord-018042-qt7055fw	118	72	,	,	,
cord-018042-qt7055fw	118	73	1997	1997	CD
cord-018042-qt7055fw	118	74	;	;	:
cord-018042-qt7055fw	118	75	Siveke	Siveke	NNP
cord-018042-qt7055fw	118	76	and	and	CC
cord-018042-qt7055fw	118	77	Hamann	Hamann	NNP
cord-018042-qt7055fw	118	78	,	,	,
cord-018042-qt7055fw	118	79	1998	1998	CD
cord-018042-qt7055fw	118	80	)	)	-RRB-
cord-018042-qt7055fw	118	81	.	.	.
cord-018042-qt7055fw	119	1	Although	although	IN
cord-018042-qt7055fw	119	2	CCL2	CCL2	NNP
cord-018042-qt7055fw	119	3	binds	bind	VBZ
cord-018042-qt7055fw	119	4	to	to	IN
cord-018042-qt7055fw	119	5	a	a	DT
cord-018042-qt7055fw	119	6	number	number	NN
cord-018042-qt7055fw	119	7	of	of	IN
cord-018042-qt7055fw	119	8	CC	cc	NN
cord-018042-qt7055fw	119	9	receptors	receptor	NNS
cord-018042-qt7055fw	120	1	the	the	DT
cord-018042-qt7055fw	120	2	primary	primary	JJ
cord-018042-qt7055fw	120	3	receptor	receptor	NN
cord-018042-qt7055fw	120	4	for	for	IN
cord-018042-qt7055fw	120	5	this	this	DT
cord-018042-qt7055fw	120	6	chemokine	chemokine	NN
cord-018042-qt7055fw	120	7	is	be	VBZ
cord-018042-qt7055fw	120	8	CCR2	CCR2	NNP
cord-018042-qt7055fw	120	9	.	.	.
cord-018042-qt7055fw	121	1	Cells	cell	NNS
cord-018042-qt7055fw	121	2	within	within	IN
cord-018042-qt7055fw	121	3	the	the	DT
cord-018042-qt7055fw	121	4	CNS	CNS	NNP
cord-018042-qt7055fw	121	5	including	include	VBG
cord-018042-qt7055fw	121	6	astrocytes	astrocyte	NNS
cord-018042-qt7055fw	121	7	and	and	CC
cord-018042-qt7055fw	121	8	microglia	microglia	NNS
cord-018042-qt7055fw	121	9	have	have	VBP
cord-018042-qt7055fw	121	10	been	be	VBN
cord-018042-qt7055fw	121	11	shown	show	VBN
cord-018042-qt7055fw	121	12	to	to	TO
cord-018042-qt7055fw	121	13	be	be	VB
cord-018042-qt7055fw	121	14	positive	positive	JJ
cord-018042-qt7055fw	121	15	for	for	IN
cord-018042-qt7055fw	121	16	CCR2	CCR2	NNP
cord-018042-qt7055fw	121	17	(	(	-LRB-
cord-018042-qt7055fw	121	18	Banisadr	Banisadr	NNP
cord-018042-qt7055fw	121	19	et	et	NNP
cord-018042-qt7055fw	121	20	al	al	NNP
cord-018042-qt7055fw	121	21	.	.	NNP
cord-018042-qt7055fw	121	22	,	,	,
cord-018042-qt7055fw	121	23	2002	2002	CD
cord-018042-qt7055fw	121	24	)	)	-RRB-
cord-018042-qt7055fw	121	25	,	,	,
cord-018042-qt7055fw	121	26	while	while	IN
cord-018042-qt7055fw	121	27	the	the	DT
cord-018042-qt7055fw	121	28	ligand	ligand	NN
cord-018042-qt7055fw	121	29	is	be	VBZ
cord-018042-qt7055fw	121	30	produced	produce	VBN
cord-018042-qt7055fw	121	31	by	by	IN
cord-018042-qt7055fw	121	32	astrocytes	astrocyte	NNS
cord-018042-qt7055fw	121	33	(	(	-LRB-
cord-018042-qt7055fw	122	1	Ransohoff	Ransohoff	NNP
cord-018042-qt7055fw	122	2	et	et	NNP
cord-018042-qt7055fw	122	3	al	al	NNP
cord-018042-qt7055fw	122	4	.	.	.
cord-018042-qt7055fw	123	1	,	,	,
cord-018042-qt7055fw	123	2	1993	1993	CD
cord-018042-qt7055fw	123	3	;	;	:
cord-018042-qt7055fw	123	4	Glabinski	Glabinski	NNP
cord-018042-qt7055fw	123	5	et	et	NNP
cord-018042-qt7055fw	123	6	al	al	NNP
cord-018042-qt7055fw	123	7	.	.	NNP
cord-018042-qt7055fw	123	8	,	,	,
cord-018042-qt7055fw	123	9	1996	1996	CD
cord-018042-qt7055fw	123	10	)	)	-RRB-
cord-018042-qt7055fw	123	11	.	.	.
cord-018042-qt7055fw	124	1	CCL2	CCL2	NNP
cord-018042-qt7055fw	124	2	is	be	VBZ
cord-018042-qt7055fw	124	3	implicated	implicate	VBN
cord-018042-qt7055fw	124	4	in	in	IN
cord-018042-qt7055fw	124	5	the	the	DT
cord-018042-qt7055fw	124	6	pathogenesis	pathogenesis	NN
cord-018042-qt7055fw	124	7	of	of	IN
cord-018042-qt7055fw	124	8	a	a	DT
cord-018042-qt7055fw	124	9	wide	wide	JJ
cord-018042-qt7055fw	124	10	variety	variety	NN
cord-018042-qt7055fw	124	11	of	of	IN
cord-018042-qt7055fw	124	12	experimental	experimental	JJ
cord-018042-qt7055fw	124	13	and	and	CC
cord-018042-qt7055fw	124	14	human	human	JJ
cord-018042-qt7055fw	124	15	neurodegenerative	neurodegenerative	JJ
cord-018042-qt7055fw	124	16	and	and	CC
cord-018042-qt7055fw	124	17	immune	immune	NN
cord-018042-qt7055fw	124	18	-	-	HYPH
cord-018042-qt7055fw	124	19	mediated	mediate	VBN
cord-018042-qt7055fw	124	20	disorders	disorder	NNS
cord-018042-qt7055fw	124	21	(	(	-LRB-
cord-018042-qt7055fw	124	22	Cartier	Cartier	NNP
cord-018042-qt7055fw	124	23	et	et	NNP
cord-018042-qt7055fw	124	24	al	al	NNP
cord-018042-qt7055fw	124	25	.	.	NNP
cord-018042-qt7055fw	124	26	,	,	,
cord-018042-qt7055fw	124	27	2005	2005	CD
cord-018042-qt7055fw	124	28	)	)	-RRB-
cord-018042-qt7055fw	124	29	.	.	.
cord-018042-qt7055fw	125	1	The	the	DT
cord-018042-qt7055fw	125	2	first	first	JJ
cord-018042-qt7055fw	125	3	transgenic	transgenic	JJ
cord-018042-qt7055fw	125	4	model	model	NN
cord-018042-qt7055fw	125	5	developed	develop	VBD
cord-018042-qt7055fw	125	6	to	to	TO
cord-018042-qt7055fw	125	7	achieve	achieve	VB
cord-018042-qt7055fw	125	8	CCL2	CCL2	NNP
cord-018042-qt7055fw	125	9	production	production	NN
cord-018042-qt7055fw	125	10	in	in	IN
cord-018042-qt7055fw	125	11	the	the	DT
cord-018042-qt7055fw	125	12	CNS	CNS	NNP
cord-018042-qt7055fw	125	13	of	of	IN
cord-018042-qt7055fw	125	14	mice	mouse	NNS
cord-018042-qt7055fw	125	15	employed	employ	VBD
cord-018042-qt7055fw	125	16	the	the	DT
cord-018042-qt7055fw	125	17	MBP	MBP	NNP
cord-018042-qt7055fw	125	18	-	-	HYPH
cord-018042-qt7055fw	125	19	promoter	promoter	NN
cord-018042-qt7055fw	125	20	to	to	TO
cord-018042-qt7055fw	125	21	drive	drive	VB
cord-018042-qt7055fw	125	22	expression	expression	NN
cord-018042-qt7055fw	125	23	of	of	IN
cord-018042-qt7055fw	125	24	the	the	DT
cord-018042-qt7055fw	125	25	CCL2	CCL2	NNP
cord-018042-qt7055fw	125	26	gene	gene	NN
cord-018042-qt7055fw	125	27	in	in	IN
cord-018042-qt7055fw	125	28	oligodendrocytes	oligodendrocyte	NNS
cord-018042-qt7055fw	125	29	(	(	-LRB-
cord-018042-qt7055fw	125	30	Fuentes	Fuentes	NNPS
cord-018042-qt7055fw	125	31	et	et	NNP
cord-018042-qt7055fw	125	32	al	al	NNP
cord-018042-qt7055fw	125	33	.	.	NNP
cord-018042-qt7055fw	125	34	,	,	,
cord-018042-qt7055fw	125	35	1995	1995	CD
cord-018042-qt7055fw	125	36	)	)	-RRB-
cord-018042-qt7055fw	125	37	.	.	.
cord-018042-qt7055fw	126	1	Temporal	temporal	JJ
cord-018042-qt7055fw	126	2	expression	expression	NN
cord-018042-qt7055fw	126	3	of	of	IN
cord-018042-qt7055fw	126	4	transgene	transgene	NN
cord-018042-qt7055fw	126	5	-	-	HYPH
cord-018042-qt7055fw	126	6	encoded	encode	VBN
cord-018042-qt7055fw	126	7	CCL2	CCL2	NNP
cord-018042-qt7055fw	126	8	RNA	RNA	NNP
cord-018042-qt7055fw	126	9	followed	follow	VBD
cord-018042-qt7055fw	126	10	that	that	DT
cord-018042-qt7055fw	126	11	of	of	IN
cord-018042-qt7055fw	126	12	endogenous	endogenous	JJ
cord-018042-qt7055fw	126	13	MBP	MBP	NNP
cord-018042-qt7055fw	126	14	peaking	peak	VBG
cord-018042-qt7055fw	126	15	between	between	IN
cord-018042-qt7055fw	126	16	the	the	DT
cord-018042-qt7055fw	126	17	second	second	JJ
cord-018042-qt7055fw	126	18	and	and	CC
cord-018042-qt7055fw	126	19	third	third	JJ
cord-018042-qt7055fw	126	20	post	post	JJ
cord-018042-qt7055fw	126	21	-	-	JJ
cord-018042-qt7055fw	126	22	natal	natal	JJ
cord-018042-qt7055fw	126	23	week	week	NN
cord-018042-qt7055fw	126	24	before	before	IN
cord-018042-qt7055fw	126	25	declining	decline	VBG
cord-018042-qt7055fw	126	26	.	.	.
cord-018042-qt7055fw	127	1	In	in	IN
cord-018042-qt7055fw	127	2	addition	addition	NN
cord-018042-qt7055fw	127	3	,	,	,
cord-018042-qt7055fw	127	4	CCL2	CCL2	NNP
cord-018042-qt7055fw	127	5	protein	protein	NN
cord-018042-qt7055fw	127	6	was	be	VBD
cord-018042-qt7055fw	127	7	demonstrated	demonstrate	VBN
cord-018042-qt7055fw	127	8	to	to	TO
cord-018042-qt7055fw	127	9	be	be	VB
cord-018042-qt7055fw	127	10	present	present	JJ
cord-018042-qt7055fw	127	11	in	in	IN
cord-018042-qt7055fw	127	12	the	the	DT
cord-018042-qt7055fw	127	13	brain	brain	NN
cord-018042-qt7055fw	127	14	of	of	IN
cord-018042-qt7055fw	127	15	the	the	DT
cord-018042-qt7055fw	127	16	transgenic	transgenic	JJ
cord-018042-qt7055fw	127	17	but	but	CC
cord-018042-qt7055fw	127	18	not	not	RB
cord-018042-qt7055fw	127	19	wild	wild	JJ
cord-018042-qt7055fw	127	20	type	type	NN
cord-018042-qt7055fw	127	21	mice	mouse	NNS
cord-018042-qt7055fw	127	22	during	during	IN
cord-018042-qt7055fw	127	23	peak	peak	NN
cord-018042-qt7055fw	127	24	transgene	transgene	NN
cord-018042-qt7055fw	127	25	gene	gene	NN
cord-018042-qt7055fw	127	26	expression	expression	NN
cord-018042-qt7055fw	127	27	.	.	.
cord-018042-qt7055fw	128	1	In	in	IN
cord-018042-qt7055fw	128	2	concordance	concordance	NN
cord-018042-qt7055fw	128	3	with	with	IN
cord-018042-qt7055fw	128	4	the	the	DT
cord-018042-qt7055fw	128	5	temporal	temporal	JJ
cord-018042-qt7055fw	128	6	profile	profile	NN
cord-018042-qt7055fw	128	7	of	of	IN
cord-018042-qt7055fw	128	8	transgene	transgene	NN
cord-018042-qt7055fw	128	9	-	-	HYPH
cord-018042-qt7055fw	128	10	encoded	encode	VBN
cord-018042-qt7055fw	128	11	CCL2	CCL2	NNP
cord-018042-qt7055fw	128	12	production	production	NN
cord-018042-qt7055fw	128	13	,	,	,
cord-018042-qt7055fw	128	14	discrete	discrete	JJ
cord-018042-qt7055fw	128	15	monocytic	monocytic	JJ
cord-018042-qt7055fw	128	16	cell	cell	NN
cord-018042-qt7055fw	128	17	infiltrates	infiltrate	NNS
cord-018042-qt7055fw	128	18	were	be	VBD
cord-018042-qt7055fw	128	19	observed	observe	VBN
cord-018042-qt7055fw	128	20	throughout	throughout	IN
cord-018042-qt7055fw	128	21	the	the	DT
cord-018042-qt7055fw	128	22	brain	brain	NN
cord-018042-qt7055fw	128	23	predominantly	predominantly	RB
cord-018042-qt7055fw	128	24	in	in	IN
cord-018042-qt7055fw	128	25	perivascular	perivascular	JJ
cord-018042-qt7055fw	128	26	sites	site	NNS
cord-018042-qt7055fw	128	27	in	in	IN
cord-018042-qt7055fw	128	28	the	the	DT
cord-018042-qt7055fw	128	29	meninges	meninge	NNS
cord-018042-qt7055fw	128	30	,	,	,
cord-018042-qt7055fw	128	31	choroid	choroid	JJ
cord-018042-qt7055fw	128	32	plexus	plexus	NN
cord-018042-qt7055fw	128	33	,	,	,
cord-018042-qt7055fw	128	34	and	and	CC
cord-018042-qt7055fw	128	35	brain	brain	NN
cord-018042-qt7055fw	128	36	parenchymal	parenchymal	NN
cord-018042-qt7055fw	128	37	white	white	JJ
cord-018042-qt7055fw	128	38	matter	matter	NN
cord-018042-qt7055fw	128	39	.	.	.
cord-018042-qt7055fw	129	1	The	the	DT
cord-018042-qt7055fw	129	2	intensity	intensity	NN
cord-018042-qt7055fw	129	3	of	of	IN
cord-018042-qt7055fw	129	4	these	these	DT
cord-018042-qt7055fw	129	5	infiltrates	infiltrate	NNS
cord-018042-qt7055fw	129	6	could	could	MD
cord-018042-qt7055fw	129	7	be	be	VB
cord-018042-qt7055fw	129	8	increased	increase	VBN
cord-018042-qt7055fw	129	9	as	as	RB
cord-018042-qt7055fw	129	10	well	well	RB
cord-018042-qt7055fw	129	11	as	as	IN
cord-018042-qt7055fw	129	12	further	further	JJ
cord-018042-qt7055fw	129	13	parenchymal	parenchymal	JJ
cord-018042-qt7055fw	129	14	infiltration	infiltration	NN
cord-018042-qt7055fw	129	15	stimulated	stimulate	VBN
cord-018042-qt7055fw	129	16	,	,	,
cord-018042-qt7055fw	129	17	following	follow	VBG
cord-018042-qt7055fw	129	18	systemic	systemic	JJ
cord-018042-qt7055fw	129	19	LPS	LPS	NNP
cord-018042-qt7055fw	129	20	administration	administration	NN
cord-018042-qt7055fw	129	21	to	to	IN
cord-018042-qt7055fw	129	22	the	the	DT
cord-018042-qt7055fw	129	23	MBP	MBP	NNP
cord-018042-qt7055fw	129	24	-	-	HYPH
cord-018042-qt7055fw	129	25	MCP1	MCP1	NNP
cord-018042-qt7055fw	129	26	transgenic	transgenic	JJ
cord-018042-qt7055fw	129	27	mice	mouse	NNS
cord-018042-qt7055fw	129	28	.	.	.
cord-018042-qt7055fw	130	1	Importantly	importantly	RB
cord-018042-qt7055fw	130	2	,	,	,
cord-018042-qt7055fw	130	3	there	there	EX
cord-018042-qt7055fw	130	4	was	be	VBD
cord-018042-qt7055fw	130	5	no	no	DT
cord-018042-qt7055fw	130	6	evidence	evidence	NN
cord-018042-qt7055fw	130	7	of	of	IN
cord-018042-qt7055fw	130	8	either	either	CC
cord-018042-qt7055fw	130	9	spontaneous	spontaneous	JJ
cord-018042-qt7055fw	130	10	or	or	CC
cord-018042-qt7055fw	130	11	stimulus	stimulus	NN
cord-018042-qt7055fw	130	12	-	-	HYPH
cord-018042-qt7055fw	130	13	evoked	evoke	VBN
cord-018042-qt7055fw	130	14	CNS	CNS	NNP
cord-018042-qt7055fw	130	15	injury	injury	NN
cord-018042-qt7055fw	130	16	,	,	,
cord-018042-qt7055fw	130	17	particularly	particularly	RB
cord-018042-qt7055fw	130	18	in	in	IN
cord-018042-qt7055fw	130	19	white	white	JJ
cord-018042-qt7055fw	130	20	matter	matter	NN
cord-018042-qt7055fw	130	21	,	,	,
cord-018042-qt7055fw	130	22	in	in	IN
cord-018042-qt7055fw	130	23	these	these	DT
cord-018042-qt7055fw	130	24	transgenic	transgenic	JJ
cord-018042-qt7055fw	130	25	mice	mouse	NNS
cord-018042-qt7055fw	130	26	.	.	.
cord-018042-qt7055fw	131	1	The	the	DT
cord-018042-qt7055fw	131	2	observations	observation	NNS
cord-018042-qt7055fw	131	3	in	in	IN
cord-018042-qt7055fw	131	4	this	this	DT
cord-018042-qt7055fw	131	5	model	model	NN
cord-018042-qt7055fw	131	6	confirmed	confirm	VBD
cord-018042-qt7055fw	131	7	the	the	DT
cord-018042-qt7055fw	131	8	potent	potent	JJ
cord-018042-qt7055fw	131	9	monocyte	monocyte	NNP
cord-018042-qt7055fw	131	10	chemoattractant	chemoattractant	NN
cord-018042-qt7055fw	131	11	properties	property	NNS
cord-018042-qt7055fw	131	12	of	of	IN
cord-018042-qt7055fw	131	13	CCL2	CCL2	NNP
cord-018042-qt7055fw	131	14	and	and	CC
cord-018042-qt7055fw	131	15	further	further	RB
cord-018042-qt7055fw	131	16	indicate	indicate	VBP
cord-018042-qt7055fw	131	17	that	that	IN
cord-018042-qt7055fw	131	18	while	while	IN
cord-018042-qt7055fw	131	19	CCL2	CCL2	NNP
cord-018042-qt7055fw	131	20	can	can	MD
cord-018042-qt7055fw	131	21	provide	provide	VB
cord-018042-qt7055fw	131	22	a	a	DT
cord-018042-qt7055fw	131	23	signal	signal	NN
cord-018042-qt7055fw	131	24	for	for	IN
cord-018042-qt7055fw	131	25	the	the	DT
cord-018042-qt7055fw	131	26	recruitment	recruitment	NN
cord-018042-qt7055fw	131	27	of	of	IN
cord-018042-qt7055fw	131	28	these	these	DT
cord-018042-qt7055fw	131	29	cells	cell	NNS
cord-018042-qt7055fw	131	30	to	to	IN
cord-018042-qt7055fw	131	31	the	the	DT
cord-018042-qt7055fw	131	32	CNS	CNS	NNP
cord-018042-qt7055fw	131	33	,	,	,
cord-018042-qt7055fw	131	34	the	the	DT
cord-018042-qt7055fw	131	35	chemokine	chemokine	NN
cord-018042-qt7055fw	131	36	does	do	VBZ
cord-018042-qt7055fw	131	37	not	not	RB
cord-018042-qt7055fw	131	38	directly	directly	RB
cord-018042-qt7055fw	131	39	stimulate	stimulate	VB
cord-018042-qt7055fw	131	40	these	these	DT
cord-018042-qt7055fw	131	41	cells	cell	NNS
cord-018042-qt7055fw	131	42	to	to	TO
cord-018042-qt7055fw	131	43	engage	engage	VB
cord-018042-qt7055fw	131	44	in	in	IN
cord-018042-qt7055fw	131	45	an	an	DT
cord-018042-qt7055fw	131	46	active	active	JJ
cord-018042-qt7055fw	131	47	inflammatory	inflammatory	JJ
cord-018042-qt7055fw	131	48	process	process	NN
cord-018042-qt7055fw	131	49	.	.	.
cord-018042-qt7055fw	132	1	However	however	RB
cord-018042-qt7055fw	132	2	,	,	,
cord-018042-qt7055fw	132	3	a	a	DT
cord-018042-qt7055fw	132	4	more	more	RBR
cord-018042-qt7055fw	132	5	recent	recent	JJ
cord-018042-qt7055fw	132	6	study	study	NN
cord-018042-qt7055fw	132	7	using	use	VBG
cord-018042-qt7055fw	132	8	these	these	DT
cord-018042-qt7055fw	132	9	transgenic	transgenic	JJ
cord-018042-qt7055fw	132	10	mice	mouse	NNS
cord-018042-qt7055fw	132	11	revealed	reveal	VBD
cord-018042-qt7055fw	132	12	that	that	IN
cord-018042-qt7055fw	132	13	a	a	DT
cord-018042-qt7055fw	132	14	systemic	systemic	JJ
cord-018042-qt7055fw	132	15	injection	injection	NN
cord-018042-qt7055fw	132	16	of	of	IN
cord-018042-qt7055fw	132	17	pertussis	pertussis	NN
cord-018042-qt7055fw	132	18	toxin	toxin	NN
cord-018042-qt7055fw	132	19	can	can	MD
cord-018042-qt7055fw	132	20	induce	induce	VB
cord-018042-qt7055fw	132	21	a	a	DT
cord-018042-qt7055fw	132	22	reversible	reversible	JJ
cord-018042-qt7055fw	132	23	encephalopathy	encephalopathy	NN
cord-018042-qt7055fw	132	24	with	with	IN
cord-018042-qt7055fw	132	25	clinical	clinical	JJ
cord-018042-qt7055fw	132	26	signs	sign	NNS
cord-018042-qt7055fw	132	27	,	,	,
cord-018042-qt7055fw	132	28	including	include	VBG
cord-018042-qt7055fw	132	29	tremor	tremor	NN
cord-018042-qt7055fw	132	30	,	,	,
cord-018042-qt7055fw	132	31	inactivity	inactivity	NN
cord-018042-qt7055fw	132	32	,	,	,
cord-018042-qt7055fw	132	33	limb	limb	NN
cord-018042-qt7055fw	132	34	clasping	clasping	NN
cord-018042-qt7055fw	132	35	and	and	CC
cord-018042-qt7055fw	132	36	weight	weight	NN
cord-018042-qt7055fw	132	37	loss	loss	NN
cord-018042-qt7055fw	133	1	(	(	-LRB-
cord-018042-qt7055fw	133	2	Toft	Toft	NNP
cord-018042-qt7055fw	133	3	-	-	HYPH
cord-018042-qt7055fw	133	4	Hansen	Hansen	NNP
cord-018042-qt7055fw	133	5	et	et	NNP
cord-018042-qt7055fw	133	6	al	al	NNP
cord-018042-qt7055fw	133	7	.	.	NNP
cord-018042-qt7055fw	133	8	,	,	,
cord-018042-qt7055fw	133	9	2006	2006	CD
cord-018042-qt7055fw	133	10	)	)	-RRB-
cord-018042-qt7055fw	133	11	.	.	.
cord-018042-qt7055fw	134	1	Encephalopathic	encephalopathic	JJ
cord-018042-qt7055fw	134	2	signs	sign	NNS
cord-018042-qt7055fw	134	3	were	be	VBD
cord-018042-qt7055fw	134	4	correlated	correlate	VBN
cord-018042-qt7055fw	134	5	with	with	IN
cord-018042-qt7055fw	134	6	a	a	DT
cord-018042-qt7055fw	134	7	more	more	RBR
cord-018042-qt7055fw	134	8	diffuse	diffuse	JJ
cord-018042-qt7055fw	134	9	distribution	distribution	NN
cord-018042-qt7055fw	134	10	of	of	IN
cord-018042-qt7055fw	134	11	monocytes	monocyte	NNS
cord-018042-qt7055fw	134	12	,	,	,
cord-018042-qt7055fw	134	13	which	which	WDT
cord-018042-qt7055fw	134	14	were	be	VBD
cord-018042-qt7055fw	134	15	less	less	RBR
cord-018042-qt7055fw	134	16	restricted	restricted	JJ
cord-018042-qt7055fw	134	17	to	to	IN
cord-018042-qt7055fw	134	18	the	the	DT
cord-018042-qt7055fw	134	19	perivascular	perivascular	JJ
cord-018042-qt7055fw	134	20	space	space	NN
cord-018042-qt7055fw	134	21	suggesting	suggest	VBG
cord-018042-qt7055fw	134	22	a	a	DT
cord-018042-qt7055fw	134	23	role	role	NN
cord-018042-qt7055fw	134	24	for	for	IN
cord-018042-qt7055fw	134	25	the	the	DT
cord-018042-qt7055fw	134	26	inflammatory	inflammatory	JJ
cord-018042-qt7055fw	134	27	process	process	NN
cord-018042-qt7055fw	134	28	in	in	IN
cord-018042-qt7055fw	134	29	the	the	DT
cord-018042-qt7055fw	134	30	clinical	clinical	JJ
cord-018042-qt7055fw	134	31	symptoms	symptom	NNS
cord-018042-qt7055fw	134	32	.	.	.
cord-018042-qt7055fw	135	1	However	however	RB
cord-018042-qt7055fw	135	2	the	the	DT
cord-018042-qt7055fw	135	3	pathological	pathological	JJ
cord-018042-qt7055fw	135	4	basis	basis	NN
cord-018042-qt7055fw	135	5	for	for	IN
cord-018042-qt7055fw	135	6	the	the	DT
cord-018042-qt7055fw	135	7	physical	physical	JJ
cord-018042-qt7055fw	135	8	impairments	impairment	NNS
cord-018042-qt7055fw	135	9	in	in	IN
cord-018042-qt7055fw	135	10	these	these	DT
cord-018042-qt7055fw	135	11	mice	mouse	NNS
cord-018042-qt7055fw	135	12	was	be	VBD
cord-018042-qt7055fw	135	13	not	not	RB
cord-018042-qt7055fw	135	14	determined	determined	JJ
cord-018042-qt7055fw	135	15	and	and	CC
cord-018042-qt7055fw	135	16	it	-PRON-	PRP
cord-018042-qt7055fw	135	17	therefore	therefore	RB
cord-018042-qt7055fw	135	18	remains	remain	VBZ
cord-018042-qt7055fw	135	19	unclear	unclear	JJ
cord-018042-qt7055fw	135	20	whether	whether	IN
cord-018042-qt7055fw	135	21	tissue	tissue	NN
cord-018042-qt7055fw	135	22	injury	injury	NN
cord-018042-qt7055fw	135	23	was	be	VBD
cord-018042-qt7055fw	135	24	also	also	RB
cord-018042-qt7055fw	135	25	involved	involve	VBN
cord-018042-qt7055fw	135	26	.	.	.
cord-018042-qt7055fw	136	1	Increased	increase	VBN
cord-018042-qt7055fw	136	2	levels	level	NNS
cord-018042-qt7055fw	136	3	of	of	IN
cord-018042-qt7055fw	136	4	metalloproteinases	metalloproteinase	NNS
cord-018042-qt7055fw	136	5	were	be	VBD
cord-018042-qt7055fw	136	6	found	find	VBN
cord-018042-qt7055fw	136	7	in	in	IN
cord-018042-qt7055fw	136	8	pertussis	pertussis	NN
cord-018042-qt7055fw	136	9	toxin	toxin	NN
cord-018042-qt7055fw	136	10	treated	treat	VBN
cord-018042-qt7055fw	136	11	MBP	MBP	NNP
cord-018042-qt7055fw	136	12	-	-	HYPH
cord-018042-qt7055fw	136	13	CCL2	CCL2	NNP
cord-018042-qt7055fw	136	14	transgenic	transgenic	JJ
cord-018042-qt7055fw	136	15	mice	mouse	NNS
cord-018042-qt7055fw	136	16	,	,	,
cord-018042-qt7055fw	136	17	suggesting	suggest	VBG
cord-018042-qt7055fw	136	18	a	a	DT
cord-018042-qt7055fw	136	19	critical	critical	JJ
cord-018042-qt7055fw	136	20	need	need	NN
cord-018042-qt7055fw	136	21	for	for	IN
cord-018042-qt7055fw	136	22	metalloproteinases	metalloproteinase	NNS
cord-018042-qt7055fw	136	23	for	for	IN
cord-018042-qt7055fw	136	24	the	the	DT
cord-018042-qt7055fw	136	25	parenchymal	parenchymal	JJ
cord-018042-qt7055fw	136	26	infiltration	infiltration	NN
cord-018042-qt7055fw	136	27	of	of	IN
cord-018042-qt7055fw	136	28	the	the	DT
cord-018042-qt7055fw	136	29	monocytes	monocyte	NNS
cord-018042-qt7055fw	136	30	.	.	.
cord-018042-qt7055fw	137	1	Weight	weight	NN
cord-018042-qt7055fw	137	2	loss	loss	NN
cord-018042-qt7055fw	137	3	and	and	CC
cord-018042-qt7055fw	137	4	parenchymal	parenchymal	NN
cord-018042-qt7055fw	137	5	infiltration	infiltration	NN
cord-018042-qt7055fw	137	6	,	,	,
cord-018042-qt7055fw	137	7	but	but	CC
cord-018042-qt7055fw	137	8	not	not	RB
cord-018042-qt7055fw	137	9	perivascular	perivascular	JJ
cord-018042-qt7055fw	137	10	accumulation	accumulation	NN
cord-018042-qt7055fw	137	11	,	,	,
cord-018042-qt7055fw	137	12	were	be	VBD
cord-018042-qt7055fw	137	13	markedly	markedly	RB
cord-018042-qt7055fw	137	14	resolved	resolve	VBN
cord-018042-qt7055fw	137	15	by	by	IN
cord-018042-qt7055fw	137	16	the	the	DT
cord-018042-qt7055fw	137	17	broad	broad	JJ
cord-018042-qt7055fw	137	18	-	-	HYPH
cord-018042-qt7055fw	137	19	spectrum	spectrum	NN
cord-018042-qt7055fw	137	20	metalloproteinase	metalloproteinase	NN
cord-018042-qt7055fw	137	21	inhibitor	inhibitor	NN
cord-018042-qt7055fw	137	22	BB-94	BB-94	NNP
cord-018042-qt7055fw	137	23	/	/	SYM
cord-018042-qt7055fw	137	24	Batimastat	Batimastat	NNP
cord-018042-qt7055fw	137	25	.	.	.
cord-018042-qt7055fw	138	1	The	the	DT
cord-018042-qt7055fw	138	2	findings	finding	NNS
cord-018042-qt7055fw	138	3	suggest	suggest	VBP
cord-018042-qt7055fw	138	4	that	that	IN
cord-018042-qt7055fw	138	5	a	a	DT
cord-018042-qt7055fw	138	6	critical	critical	JJ
cord-018042-qt7055fw	138	7	event	event	NN
cord-018042-qt7055fw	138	8	in	in	IN
cord-018042-qt7055fw	138	9	inducing	induce	VBG
cord-018042-qt7055fw	138	10	disease	disease	NN
cord-018042-qt7055fw	138	11	in	in	IN
cord-018042-qt7055fw	138	12	this	this	DT
cord-018042-qt7055fw	138	13	model	model	NN
cord-018042-qt7055fw	138	14	is	be	VBZ
cord-018042-qt7055fw	138	15	metalloproteinase	metalloproteinase	NN
cord-018042-qt7055fw	138	16	-	-	HYPH
cord-018042-qt7055fw	138	17	dependent	dependent	JJ
cord-018042-qt7055fw	138	18	leukocyte	leukocyte	NN
cord-018042-qt7055fw	138	19	migration	migration	NN
cord-018042-qt7055fw	138	20	across	across	IN
cord-018042-qt7055fw	138	21	the	the	DT
cord-018042-qt7055fw	138	22	astroglial	astroglial	JJ
cord-018042-qt7055fw	138	23	basement	basement	NN
cord-018042-qt7055fw	138	24	membrane	membrane	NN
cord-018042-qt7055fw	138	25	of	of	IN
cord-018042-qt7055fw	138	26	the	the	DT
cord-018042-qt7055fw	138	27	blood	blood	NN
cord-018042-qt7055fw	138	28	-	-	HYPH
cord-018042-qt7055fw	138	29	brain	brain	NN
cord-018042-qt7055fw	138	30	barrier	barrier	NN
cord-018042-qt7055fw	138	31	,	,	,
cord-018042-qt7055fw	138	32	which	which	WDT
cord-018042-qt7055fw	138	33	is	be	VBZ
cord-018042-qt7055fw	138	34	induced	induce	VBN
cord-018042-qt7055fw	138	35	by	by	IN
cord-018042-qt7055fw	138	36	pertussis	pertussis	NN
cord-018042-qt7055fw	138	37	toxin	toxin	NN
cord-018042-qt7055fw	138	38	.	.	.
cord-018042-qt7055fw	139	1	As	as	IN
cord-018042-qt7055fw	139	2	noted	note	VBN
cord-018042-qt7055fw	139	3	above	above	RB
cord-018042-qt7055fw	139	4	,	,	,
cord-018042-qt7055fw	139	5	astrocytes	astrocyte	NNS
cord-018042-qt7055fw	139	6	but	but	CC
cord-018042-qt7055fw	139	7	not	not	RB
cord-018042-qt7055fw	139	8	oligodendrocytes	oligodendrocyte	NNS
cord-018042-qt7055fw	139	9	have	have	VBP
cord-018042-qt7055fw	139	10	been	be	VBN
cord-018042-qt7055fw	139	11	found	find	VBN
cord-018042-qt7055fw	139	12	to	to	TO
cord-018042-qt7055fw	139	13	be	be	VB
cord-018042-qt7055fw	139	14	a	a	DT
cord-018042-qt7055fw	139	15	major	major	JJ
cord-018042-qt7055fw	139	16	source	source	NN
cord-018042-qt7055fw	139	17	of	of	IN
cord-018042-qt7055fw	139	18	CCL2	CCL2	NNP
cord-018042-qt7055fw	139	19	in	in	IN
cord-018042-qt7055fw	139	20	various	various	JJ
cord-018042-qt7055fw	139	21	CNS	CNS	NNP
cord-018042-qt7055fw	139	22	pathologies	pathology	NNS
cord-018042-qt7055fw	139	23	.	.	.
cord-018042-qt7055fw	140	1	The	the	DT
cord-018042-qt7055fw	140	2	production	production	NN
cord-018042-qt7055fw	140	3	of	of	IN
cord-018042-qt7055fw	140	4	CCL2	CCL2	NNP
cord-018042-qt7055fw	140	5	under	under	IN
cord-018042-qt7055fw	140	6	the	the	DT
cord-018042-qt7055fw	140	7	control	control	NN
cord-018042-qt7055fw	140	8	of	of	IN
cord-018042-qt7055fw	140	9	the	the	DT
cord-018042-qt7055fw	140	10	MBP	MBP	NNP
cord-018042-qt7055fw	140	11	-	-	HYPH
cord-018042-qt7055fw	140	12	promoter	promoter	NN
cord-018042-qt7055fw	140	13	follows	follow	VBZ
cord-018042-qt7055fw	140	14	a	a	DT
cord-018042-qt7055fw	140	15	similar	similar	JJ
cord-018042-qt7055fw	140	16	temporal	temporal	JJ
cord-018042-qt7055fw	140	17	pattern	pattern	NN
cord-018042-qt7055fw	140	18	as	as	IN
cord-018042-qt7055fw	140	19	the	the	DT
cord-018042-qt7055fw	140	20	endogenous	endogenous	JJ
cord-018042-qt7055fw	140	21	gene	gene	NN
cord-018042-qt7055fw	140	22	and	and	CC
cord-018042-qt7055fw	140	23	produces	produce	VBZ
cord-018042-qt7055fw	140	24	a	a	DT
cord-018042-qt7055fw	140	25	spike	spike	NN
cord-018042-qt7055fw	140	26	of	of	IN
cord-018042-qt7055fw	140	27	CCL2	CCL2	NNP
cord-018042-qt7055fw	140	28	activity	activity	NN
cord-018042-qt7055fw	140	29	.	.	.
cord-018042-qt7055fw	141	1	The	the	DT
cord-018042-qt7055fw	141	2	delivery	delivery	NN
cord-018042-qt7055fw	141	3	of	of	IN
cord-018042-qt7055fw	141	4	maximal	maximal	JJ
cord-018042-qt7055fw	141	5	transgene	transgene	NN
cord-018042-qt7055fw	141	6	-	-	HYPH
cord-018042-qt7055fw	141	7	derived	derive	VBN
cord-018042-qt7055fw	141	8	CCL2	CCL2	NNP
cord-018042-qt7055fw	141	9	in	in	IN
cord-018042-qt7055fw	141	10	this	this	DT
cord-018042-qt7055fw	141	11	model	model	NN
cord-018042-qt7055fw	141	12	occurs	occur	VBZ
cord-018042-qt7055fw	141	13	during	during	IN
cord-018042-qt7055fw	141	14	a	a	DT
cord-018042-qt7055fw	141	15	developmentally	developmentally	RB
cord-018042-qt7055fw	141	16	sensitive	sensitive	JJ
cord-018042-qt7055fw	141	17	period	period	NN
cord-018042-qt7055fw	141	18	before	before	IN
cord-018042-qt7055fw	141	19	subsiding	subside	VBG
cord-018042-qt7055fw	141	20	making	make	VBG
cord-018042-qt7055fw	141	21	this	this	DT
cord-018042-qt7055fw	141	22	model	model	NN
cord-018042-qt7055fw	141	23	less	less	RBR
cord-018042-qt7055fw	141	24	relevant	relevant	JJ
cord-018042-qt7055fw	141	25	for	for	IN
cord-018042-qt7055fw	141	26	studying	study	VBG
cord-018042-qt7055fw	141	27	the	the	DT
cord-018042-qt7055fw	141	28	effects	effect	NNS
cord-018042-qt7055fw	141	29	of	of	IN
cord-018042-qt7055fw	141	30	CCL2	CCL2	NNP
cord-018042-qt7055fw	141	31	on	on	IN
cord-018042-qt7055fw	141	32	the	the	DT
cord-018042-qt7055fw	141	33	adult	adult	NN
cord-018042-qt7055fw	141	34	brain	brain	NN
cord-018042-qt7055fw	141	35	.	.	.
cord-018042-qt7055fw	142	1	In	in	IN
cord-018042-qt7055fw	142	2	order	order	NN
cord-018042-qt7055fw	142	3	to	to	TO
cord-018042-qt7055fw	142	4	address	address	VB
cord-018042-qt7055fw	142	5	these	these	DT
cord-018042-qt7055fw	142	6	issues	issue	NNS
cord-018042-qt7055fw	142	7	,	,	,
cord-018042-qt7055fw	142	8	Huang	Huang	NNP
cord-018042-qt7055fw	142	9	and	and	CC
cord-018042-qt7055fw	142	10	co	co	NNS
cord-018042-qt7055fw	142	11	-	-	NNS
cord-018042-qt7055fw	142	12	workers	worker	NNS
cord-018042-qt7055fw	142	13	generated	generate	VBD
cord-018042-qt7055fw	142	14	transgenic	transgenic	JJ
cord-018042-qt7055fw	142	15	mice	mouse	NNS
cord-018042-qt7055fw	142	16	with	with	IN
cord-018042-qt7055fw	142	17	astrocyte	astrocyte	RB
cord-018042-qt7055fw	142	18	-	-	HYPH
cord-018042-qt7055fw	142	19	targeted	target	VBN
cord-018042-qt7055fw	142	20	expression	expression	NN
cord-018042-qt7055fw	142	21	of	of	IN
cord-018042-qt7055fw	142	22	the	the	DT
cord-018042-qt7055fw	142	23	CCL2	CCL2	NNP
cord-018042-qt7055fw	142	24	gene	gene	NN
cord-018042-qt7055fw	142	25	driven	drive	VBN
cord-018042-qt7055fw	142	26	by	by	IN
cord-018042-qt7055fw	142	27	the	the	DT
cord-018042-qt7055fw	142	28	human	human	JJ
cord-018042-qt7055fw	142	29	GFAP	GFAP	NNP
cord-018042-qt7055fw	142	30	promoter	promoter	NN
cord-018042-qt7055fw	142	31	(	(	-LRB-
cord-018042-qt7055fw	142	32	Huang	Huang	NNP
cord-018042-qt7055fw	142	33	et	et	NNP
cord-018042-qt7055fw	142	34	al	al	NNP
cord-018042-qt7055fw	142	35	.	.	NNP
cord-018042-qt7055fw	142	36	,	,	,
cord-018042-qt7055fw	142	37	2002	2002	CD
cord-018042-qt7055fw	142	38	.	.	.
cord-018042-qt7055fw	143	1	These	these	DT
cord-018042-qt7055fw	143	2	GFAP	GFAP	NNP
cord-018042-qt7055fw	143	3	-	-	HYPH
cord-018042-qt7055fw	143	4	CCL2	CCL2	NNP
cord-018042-qt7055fw	143	5	transgenic	transgenic	JJ
cord-018042-qt7055fw	143	6	mice	mouse	NNS
cord-018042-qt7055fw	143	7	produced	produce	VBD
cord-018042-qt7055fw	143	8	CCL2	CCL2	NNP
cord-018042-qt7055fw	143	9	in	in	IN
cord-018042-qt7055fw	143	10	the	the	DT
cord-018042-qt7055fw	143	11	CNS	CNS	NNP
cord-018042-qt7055fw	143	12	at	at	IN
cord-018042-qt7055fw	143	13	levels	level	NNS
cord-018042-qt7055fw	143	14	similar	similar	JJ
cord-018042-qt7055fw	143	15	to	to	IN
cord-018042-qt7055fw	143	16	those	those	DT
cord-018042-qt7055fw	143	17	produced	produce	VBN
cord-018042-qt7055fw	143	18	during	during	IN
cord-018042-qt7055fw	143	19	EAE	EAE	NNP
cord-018042-qt7055fw	143	20	,	,	,
cord-018042-qt7055fw	143	21	yet	yet	CC
cord-018042-qt7055fw	143	22	,	,	,
cord-018042-qt7055fw	143	23	these	these	DT
cord-018042-qt7055fw	143	24	animals	animal	NNS
cord-018042-qt7055fw	143	25	exhibited	exhibit	VBD
cord-018042-qt7055fw	143	26	little	little	JJ
cord-018042-qt7055fw	143	27	spontaneous	spontaneous	JJ
cord-018042-qt7055fw	143	28	inflammation	inflammation	NN
cord-018042-qt7055fw	143	29	.	.	.
cord-018042-qt7055fw	144	1	This	this	DT
cord-018042-qt7055fw	144	2	contrasts	contrast	VBZ
cord-018042-qt7055fw	144	3	with	with	IN
cord-018042-qt7055fw	144	4	the	the	DT
cord-018042-qt7055fw	144	5	MBP	MBP	NNP
cord-018042-qt7055fw	144	6	-	-	HYPH
cord-018042-qt7055fw	144	7	CCL2	CCL2	NNP
cord-018042-qt7055fw	144	8	transgenic	transgenic	JJ
cord-018042-qt7055fw	144	9	mouse	mouse	NN
cord-018042-qt7055fw	144	10	model	model	NN
cord-018042-qt7055fw	144	11	in	in	IN
cord-018042-qt7055fw	144	12	which	which	WDT
cord-018042-qt7055fw	144	13	widespread	widespread	JJ
cord-018042-qt7055fw	144	14	and	and	CC
cord-018042-qt7055fw	144	15	marked	mark	VBD
cord-018042-qt7055fw	144	16	perivascular	perivascular	JJ
cord-018042-qt7055fw	144	17	accumulation	accumulation	NN
cord-018042-qt7055fw	144	18	of	of	IN
cord-018042-qt7055fw	144	19	monocytes	monocyte	NNS
cord-018042-qt7055fw	144	20	was	be	VBD
cord-018042-qt7055fw	144	21	seen	see	VBN
cord-018042-qt7055fw	144	22	.	.	.
cord-018042-qt7055fw	145	1	The	the	DT
cord-018042-qt7055fw	145	2	explanation	explanation	NN
cord-018042-qt7055fw	145	3	for	for	IN
cord-018042-qt7055fw	145	4	this	this	DT
cord-018042-qt7055fw	145	5	difference	difference	NN
cord-018042-qt7055fw	145	6	between	between	IN
cord-018042-qt7055fw	145	7	these	these	DT
cord-018042-qt7055fw	145	8	models	model	NNS
cord-018042-qt7055fw	145	9	is	be	VBZ
cord-018042-qt7055fw	145	10	not	not	RB
cord-018042-qt7055fw	145	11	clear	clear	JJ
cord-018042-qt7055fw	145	12	but	but	CC
cord-018042-qt7055fw	145	13	it	-PRON-	PRP
cord-018042-qt7055fw	145	14	may	may	MD
cord-018042-qt7055fw	145	15	reflect	reflect	VB
cord-018042-qt7055fw	145	16	the	the	DT
cord-018042-qt7055fw	145	17	chronic	chronic	JJ
cord-018042-qt7055fw	145	18	and	and	CC
cord-018042-qt7055fw	145	19	more	more	RBR
cord-018042-qt7055fw	145	20	generalized	generalized	JJ
cord-018042-qt7055fw	145	21	production	production	NN
cord-018042-qt7055fw	145	22	of	of	IN
cord-018042-qt7055fw	145	23	high	high	JJ
cord-018042-qt7055fw	145	24	levels	level	NNS
cord-018042-qt7055fw	145	25	of	of	IN
cord-018042-qt7055fw	145	26	CCL2	CCL2	NNP
cord-018042-qt7055fw	145	27	in	in	IN
cord-018042-qt7055fw	145	28	the	the	DT
cord-018042-qt7055fw	145	29	case	case	NN
cord-018042-qt7055fw	145	30	of	of	IN
cord-018042-qt7055fw	145	31	the	the	DT
cord-018042-qt7055fw	145	32	GFAP	GFAP	NNP
cord-018042-qt7055fw	145	33	-	-	HYPH
cord-018042-qt7055fw	145	34	CCL2	CCL2	NNP
cord-018042-qt7055fw	145	35	transgenic	transgenic	JJ
cord-018042-qt7055fw	145	36	mice	mouse	NNS
cord-018042-qt7055fw	145	37	.	.	.
cord-018042-qt7055fw	146	1	However	however	RB
cord-018042-qt7055fw	146	2	,	,	,
cord-018042-qt7055fw	146	3	systemic	systemic	JJ
cord-018042-qt7055fw	146	4	immunization	immunization	NN
cord-018042-qt7055fw	146	5	with	with	IN
cord-018042-qt7055fw	146	6	complete	complete	JJ
cord-018042-qt7055fw	146	7	Freund	Freund	NNP
cord-018042-qt7055fw	146	8	's	's	POS
cord-018042-qt7055fw	146	9	adjuvant	adjuvant	NN
cord-018042-qt7055fw	146	10	and	and	CC
cord-018042-qt7055fw	146	11	injection	injection	NN
cord-018042-qt7055fw	146	12	of	of	IN
cord-018042-qt7055fw	146	13	pertussis	pertussis	NN
cord-018042-qt7055fw	146	14	toxin	toxin	NN
cord-018042-qt7055fw	146	15	induces	induce	VBZ
cord-018042-qt7055fw	146	16	a	a	DT
cord-018042-qt7055fw	146	17	transient	transient	JJ
cord-018042-qt7055fw	146	18	encephalopathy	encephalopathy	NN
cord-018042-qt7055fw	146	19	with	with	IN
cord-018042-qt7055fw	146	20	elevated	elevated	JJ
cord-018042-qt7055fw	146	21	levels	level	NNS
cord-018042-qt7055fw	146	22	of	of	IN
cord-018042-qt7055fw	146	23	IFN	IFN	NNP
cord-018042-qt7055fw	146	24	-	-	HYPH
cord-018042-qt7055fw	146	25	γ	γ	NNP
cord-018042-qt7055fw	146	26	and	and	CC
cord-018042-qt7055fw	146	27	IL-2	IL-2	NNP
cord-018042-qt7055fw	146	28	in	in	IN
cord-018042-qt7055fw	146	29	the	the	DT
cord-018042-qt7055fw	146	30	GFAP	GFAP	NNP
cord-018042-qt7055fw	146	31	-	-	HYPH
cord-018042-qt7055fw	146	32	CCL2	CCL2	NNP
cord-018042-qt7055fw	146	33	transgenic	transgenic	JJ
cord-018042-qt7055fw	146	34	mice	mouse	NNS
cord-018042-qt7055fw	146	35	.	.	.
cord-018042-qt7055fw	147	1	Interestingly	interestingly	RB
cord-018042-qt7055fw	147	2	,	,	,
cord-018042-qt7055fw	147	3	the	the	DT
cord-018042-qt7055fw	147	4	encephalopathy	encephalopathy	NN
cord-018042-qt7055fw	147	5	was	be	VBD
cord-018042-qt7055fw	147	6	less	less	RBR
cord-018042-qt7055fw	147	7	severe	severe	JJ
cord-018042-qt7055fw	147	8	in	in	IN
cord-018042-qt7055fw	147	9	CCL2	CCL2	NNP
cord-018042-qt7055fw	147	10	transgenic	transgenic	JJ
cord-018042-qt7055fw	147	11	mice	mouse	NNS
cord-018042-qt7055fw	147	12	on	on	IN
cord-018042-qt7055fw	147	13	a	a	DT
cord-018042-qt7055fw	147	14	T	t	NN
cord-018042-qt7055fw	147	15	-	-	HYPH
cord-018042-qt7055fw	147	16	cell	cell	NN
cord-018042-qt7055fw	147	17	deficient	deficient	JJ
cord-018042-qt7055fw	147	18	background	background	NN
cord-018042-qt7055fw	147	19	,	,	,
cord-018042-qt7055fw	147	20	indicating	indicate	VBG
cord-018042-qt7055fw	147	21	the	the	DT
cord-018042-qt7055fw	147	22	involvement	involvement	NN
cord-018042-qt7055fw	147	23	of	of	IN
cord-018042-qt7055fw	147	24	T	t	NN
cord-018042-qt7055fw	147	25	-	-	HYPH
cord-018042-qt7055fw	147	26	cells	cell	NNS
cord-018042-qt7055fw	147	27	and	and	CC
cord-018042-qt7055fw	147	28	not	not	RB
cord-018042-qt7055fw	147	29	only	only	RB
cord-018042-qt7055fw	147	30	monocytes	monocyte	NNS
cord-018042-qt7055fw	147	31	in	in	IN
cord-018042-qt7055fw	147	32	the	the	DT
cord-018042-qt7055fw	147	33	observed	observed	JJ
cord-018042-qt7055fw	147	34	encephalopathy	encephalopathy	NN
cord-018042-qt7055fw	147	35	(	(	-LRB-
cord-018042-qt7055fw	147	36	Huang	Huang	NNP
cord-018042-qt7055fw	147	37	et	et	NNP
cord-018042-qt7055fw	147	38	al	al	NNP
cord-018042-qt7055fw	147	39	.	.	NNP
cord-018042-qt7055fw	147	40	,	,	,
cord-018042-qt7055fw	147	41	2002	2002	CD
cord-018042-qt7055fw	147	42	)	)	-RRB-
cord-018042-qt7055fw	147	43	.	.	.
cord-018042-qt7055fw	148	1	Moreover	moreover	RB
cord-018042-qt7055fw	148	2	,	,	,
cord-018042-qt7055fw	148	3	this	this	DT
cord-018042-qt7055fw	148	4	phenotype	phenotype	NN
cord-018042-qt7055fw	148	5	was	be	VBD
cord-018042-qt7055fw	148	6	shown	show	VBN
cord-018042-qt7055fw	148	7	to	to	TO
cord-018042-qt7055fw	148	8	be	be	VB
cord-018042-qt7055fw	148	9	dependent	dependent	JJ
cord-018042-qt7055fw	148	10	on	on	IN
cord-018042-qt7055fw	148	11	CCR2	CCR2	NNP
cord-018042-qt7055fw	148	12	indicating	indicate	VBG
cord-018042-qt7055fw	148	13	that	that	IN
cord-018042-qt7055fw	148	14	under	under	IN
cord-018042-qt7055fw	148	15	these	these	DT
cord-018042-qt7055fw	148	16	conditions	condition	NNS
cord-018042-qt7055fw	148	17	CCR2	CCR2	NNP
cord-018042-qt7055fw	148	18	is	be	VBZ
cord-018042-qt7055fw	148	19	the	the	DT
cord-018042-qt7055fw	148	20	principal	principal	JJ
cord-018042-qt7055fw	148	21	receptor	receptor	NN
cord-018042-qt7055fw	148	22	for	for	IN
cord-018042-qt7055fw	148	23	CCL2	CCL2	NNP
cord-018042-qt7055fw	148	24	in	in	IN
cord-018042-qt7055fw	148	25	the	the	DT
cord-018042-qt7055fw	148	26	murine	murine	JJ
cord-018042-qt7055fw	148	27	CNS	CNS	NNP
cord-018042-qt7055fw	148	28	.	.	.
cord-018042-qt7055fw	149	1	Although	although	IN
cord-018042-qt7055fw	149	2	a	a	DT
cord-018042-qt7055fw	149	3	number	number	NN
cord-018042-qt7055fw	149	4	of	of	IN
cord-018042-qt7055fw	149	5	studies	study	NNS
cord-018042-qt7055fw	149	6	have	have	VBP
cord-018042-qt7055fw	149	7	suggested	suggest	VBN
cord-018042-qt7055fw	149	8	that	that	IN
cord-018042-qt7055fw	149	9	CCR2	CCR2	NNP
cord-018042-qt7055fw	149	10	activation	activation	NN
cord-018042-qt7055fw	149	11	in	in	IN
cord-018042-qt7055fw	149	12	the	the	DT
cord-018042-qt7055fw	149	13	periphery	periphery	NN
cord-018042-qt7055fw	149	14	downregulates	downregulate	VBZ
cord-018042-qt7055fw	149	15	Th1-T	th1-t	NN
cord-018042-qt7055fw	149	16	-	-	HYPH
cord-018042-qt7055fw	149	17	cell	cell	NN
cord-018042-qt7055fw	149	18	development	development	NN
cord-018042-qt7055fw	149	19	and	and	CC
cord-018042-qt7055fw	149	20	can	can	MD
cord-018042-qt7055fw	149	21	augment	augment	VB
cord-018042-qt7055fw	149	22	Th2-T	Th2-T	NNP
cord-018042-qt7055fw	149	23	-	-	HYPH
cord-018042-qt7055fw	149	24	cell	cell	NN
cord-018042-qt7055fw	149	25	development	development	NN
cord-018042-qt7055fw	149	26	(	(	-LRB-
cord-018042-qt7055fw	149	27	Daly	Daly	NNP
cord-018042-qt7055fw	149	28	and	and	CC
cord-018042-qt7055fw	149	29	Rollins	Rollins	NNP
cord-018042-qt7055fw	149	30	,	,	,
cord-018042-qt7055fw	149	31	2003	2003	CD
cord-018042-qt7055fw	149	32	)	)	-RRB-
cord-018042-qt7055fw	149	33	,	,	,
cord-018042-qt7055fw	149	34	the	the	DT
cord-018042-qt7055fw	149	35	findings	finding	NNS
cord-018042-qt7055fw	149	36	in	in	IN
cord-018042-qt7055fw	149	37	the	the	DT
cord-018042-qt7055fw	149	38	GFAP	GFAP	NNP
cord-018042-qt7055fw	149	39	-	-	HYPH
cord-018042-qt7055fw	149	40	CCL2	CCL2	NNP
cord-018042-qt7055fw	149	41	transgenic	transgenic	JJ
cord-018042-qt7055fw	149	42	mouse	mouse	NN
cord-018042-qt7055fw	149	43	indicate	indicate	VBP
cord-018042-qt7055fw	149	44	that	that	IN
cord-018042-qt7055fw	149	45	in	in	IN
cord-018042-qt7055fw	149	46	the	the	DT
cord-018042-qt7055fw	149	47	CNS	CNS	NNP
cord-018042-qt7055fw	149	48	,	,	,
cord-018042-qt7055fw	149	49	CCL2	CCL2	NNP
cord-018042-qt7055fw	149	50	may	may	MD
cord-018042-qt7055fw	149	51	recruit	recruit	VB
cord-018042-qt7055fw	149	52	Th1	Th1	NNP
cord-018042-qt7055fw	149	53	T	t	NN
cord-018042-qt7055fw	149	54	-	-	HYPH
cord-018042-qt7055fw	149	55	cells	cell	NNS
cord-018042-qt7055fw	149	56	or	or	CC
cord-018042-qt7055fw	149	57	direct	direct	JJ
cord-018042-qt7055fw	149	58	T	t	NN
cord-018042-qt7055fw	149	59	-	-	HYPH
cord-018042-qt7055fw	149	60	cell	cell	NN
cord-018042-qt7055fw	149	61	polarization	polarization	NN
cord-018042-qt7055fw	149	62	toward	toward	IN
cord-018042-qt7055fw	149	63	type	type	NN
cord-018042-qt7055fw	149	64	1	1	CD
cord-018042-qt7055fw	149	65	cytokine	cytokine	NN
cord-018042-qt7055fw	149	66	production	production	NN
cord-018042-qt7055fw	149	67	.	.	.
cord-018042-qt7055fw	150	1	This	this	DT
cord-018042-qt7055fw	150	2	concept	concept	NN
cord-018042-qt7055fw	150	3	is	be	VBZ
cord-018042-qt7055fw	150	4	also	also	RB
cord-018042-qt7055fw	150	5	supported	support	VBN
cord-018042-qt7055fw	150	6	by	by	IN
cord-018042-qt7055fw	150	7	the	the	DT
cord-018042-qt7055fw	150	8	finding	finding	NN
cord-018042-qt7055fw	150	9	that	that	IN
cord-018042-qt7055fw	150	10	mice	mouse	NNS
cord-018042-qt7055fw	150	11	deficient	deficient	JJ
cord-018042-qt7055fw	150	12	for	for	IN
cord-018042-qt7055fw	150	13	the	the	DT
cord-018042-qt7055fw	150	14	CCL2	CCL2	NNP
cord-018042-qt7055fw	150	15	receptor	receptor	NN
cord-018042-qt7055fw	150	16	,	,	,
cord-018042-qt7055fw	150	17	CCR2	CCR2	NNP
cord-018042-qt7055fw	150	18	,	,	,
cord-018042-qt7055fw	150	19	are	be	VBP
cord-018042-qt7055fw	150	20	resistant	resistant	JJ
cord-018042-qt7055fw	150	21	to	to	IN
cord-018042-qt7055fw	150	22	the	the	DT
cord-018042-qt7055fw	150	23	development	development	NN
cord-018042-qt7055fw	150	24	of	of	IN
cord-018042-qt7055fw	150	25	the	the	DT
cord-018042-qt7055fw	150	26	CD4	CD4	NNP
cord-018042-qt7055fw	150	27	+	+	CC
cord-018042-qt7055fw	150	28	T	t	NN
cord-018042-qt7055fw	150	29	-	-	HYPH
cord-018042-qt7055fw	150	30	cell	cell	NN
cord-018042-qt7055fw	150	31	-	-	HYPH
cord-018042-qt7055fw	150	32	mediated	mediate	VBN
cord-018042-qt7055fw	150	33	autoimmune	autoimmune	JJ
cord-018042-qt7055fw	150	34	disease	disease	NN
cord-018042-qt7055fw	150	35	,	,	,
cord-018042-qt7055fw	150	36	EAE	EAE	NNP
cord-018042-qt7055fw	150	37	(	(	-LRB-
cord-018042-qt7055fw	150	38	Fife	Fife	NNP
cord-018042-qt7055fw	150	39	et	et	NNP
cord-018042-qt7055fw	150	40	al	al	NNP
cord-018042-qt7055fw	150	41	.	.	NNP
cord-018042-qt7055fw	150	42	,	,	,
cord-018042-qt7055fw	150	43	2000	2000	CD
cord-018042-qt7055fw	150	44	)	)	-RRB-
cord-018042-qt7055fw	150	45	.	.	.
cord-018042-qt7055fw	151	1	However	however	RB
cord-018042-qt7055fw	151	2	,	,	,
cord-018042-qt7055fw	151	3	in	in	IN
cord-018042-qt7055fw	151	4	findings	finding	NNS
cord-018042-qt7055fw	151	5	that	that	WDT
cord-018042-qt7055fw	151	6	are	be	VBP
cord-018042-qt7055fw	151	7	difficult	difficult	JJ
cord-018042-qt7055fw	151	8	to	to	TO
cord-018042-qt7055fw	151	9	reconcile	reconcile	VB
cord-018042-qt7055fw	151	10	with	with	IN
cord-018042-qt7055fw	151	11	these	these	DT
cord-018042-qt7055fw	151	12	conclusions	conclusion	NNS
cord-018042-qt7055fw	151	13	,	,	,
cord-018042-qt7055fw	151	14	it	-PRON-	PRP
cord-018042-qt7055fw	151	15	has	have	VBZ
cord-018042-qt7055fw	151	16	been	be	VBN
cord-018042-qt7055fw	151	17	reported	report	VBN
cord-018042-qt7055fw	151	18	that	that	IN
cord-018042-qt7055fw	151	19	GFAP	GFAP	NNP
cord-018042-qt7055fw	151	20	-	-	HYPH
cord-018042-qt7055fw	151	21	CCL2	CCL2	NNP
cord-018042-qt7055fw	151	22	transgenic	transgenic	JJ
cord-018042-qt7055fw	151	23	mice	mouse	NNS
cord-018042-qt7055fw	151	24	developed	develop	VBD
cord-018042-qt7055fw	151	25	significantly	significantly	RB
cord-018042-qt7055fw	151	26	milder	mild	JJR
cord-018042-qt7055fw	151	27	EAE	EAE	NNP
cord-018042-qt7055fw	151	28	disease	disease	NN
cord-018042-qt7055fw	151	29	than	than	IN
cord-018042-qt7055fw	151	30	littermate	littermate	JJ
cord-018042-qt7055fw	151	31	controls	control	NNS
cord-018042-qt7055fw	151	32	(	(	-LRB-
cord-018042-qt7055fw	151	33	Elhofy	Elhofy	NNP
cord-018042-qt7055fw	151	34	et	et	NNP
cord-018042-qt7055fw	151	35	al	al	NNP
cord-018042-qt7055fw	151	36	.	.	NNP
cord-018042-qt7055fw	151	37	,	,	,
cord-018042-qt7055fw	151	38	2005	2005	CD
cord-018042-qt7055fw	151	39	)	)	-RRB-
cord-018042-qt7055fw	151	40	.	.	.
cord-018042-qt7055fw	152	1	Antigen	antigen	NN
cord-018042-qt7055fw	152	2	-	-	HYPH
cord-018042-qt7055fw	152	3	specific	specific	JJ
cord-018042-qt7055fw	152	4	T	t	NN
cord-018042-qt7055fw	152	5	-	-	HYPH
cord-018042-qt7055fw	152	6	cells	cell	NNS
cord-018042-qt7055fw	152	7	recovered	recover	VBN
cord-018042-qt7055fw	152	8	from	from	IN
cord-018042-qt7055fw	152	9	the	the	DT
cord-018042-qt7055fw	152	10	GFAP	GFAP	NNP
cord-018042-qt7055fw	152	11	-	-	HYPH
cord-018042-qt7055fw	152	12	CCL2	CCL2	NNP
cord-018042-qt7055fw	152	13	transgenic	transgenic	JJ
cord-018042-qt7055fw	152	14	mice	mouse	NNS
cord-018042-qt7055fw	152	15	showed	show	VBD
cord-018042-qt7055fw	152	16	decrease	decrease	NN
cord-018042-qt7055fw	152	17	proliferative	proliferative	JJ
cord-018042-qt7055fw	152	18	response	response	NN
cord-018042-qt7055fw	152	19	to	to	IN
cord-018042-qt7055fw	152	20	autoantigen	autoantigen	NN
cord-018042-qt7055fw	152	21	and	and	CC
cord-018042-qt7055fw	152	22	secreted	secrete	VBD
cord-018042-qt7055fw	152	23	less	less	JJR
cord-018042-qt7055fw	152	24	IFN	IFN	NNP
cord-018042-qt7055fw	152	25	-	-	HYPH
cord-018042-qt7055fw	152	26	γ	γ	NNP
cord-018042-qt7055fw	152	27	and	and	CC
cord-018042-qt7055fw	152	28	had	have	VBD
cord-018042-qt7055fw	152	29	lower	low	JJR
cord-018042-qt7055fw	152	30	levels	level	NNS
cord-018042-qt7055fw	152	31	of	of	IN
cord-018042-qt7055fw	152	32	IL-12	IL-12	NNP
cord-018042-qt7055fw	152	33	receptor	receptor	NN
cord-018042-qt7055fw	152	34	RNA	RNA	NNP
cord-018042-qt7055fw	152	35	.	.	.
cord-018042-qt7055fw	153	1	These	these	DT
cord-018042-qt7055fw	153	2	studies	study	NNS
cord-018042-qt7055fw	153	3	suggest	suggest	VBP
cord-018042-qt7055fw	153	4	that	that	IN
cord-018042-qt7055fw	153	5	rather	rather	RB
cord-018042-qt7055fw	153	6	than	than	IN
cord-018042-qt7055fw	153	7	augmenting	augment	VBG
cord-018042-qt7055fw	153	8	Th1	th1	NN
cord-018042-qt7055fw	153	9	cells	cell	NNS
cord-018042-qt7055fw	153	10	,	,	,
cord-018042-qt7055fw	153	11	that	that	IN
cord-018042-qt7055fw	153	12	chronic	chronic	JJ
cord-018042-qt7055fw	153	13	CCL2	CCL2	NNP
cord-018042-qt7055fw	153	14	production	production	NN
cord-018042-qt7055fw	153	15	in	in	IN
cord-018042-qt7055fw	153	16	the	the	DT
cord-018042-qt7055fw	153	17	CNS	CNS	NNP
cord-018042-qt7055fw	153	18	impairs	impair	VBZ
cord-018042-qt7055fw	153	19	the	the	DT
cord-018042-qt7055fw	153	20	function	function	NN
cord-018042-qt7055fw	153	21	of	of	IN
cord-018042-qt7055fw	153	22	these	these	DT
cord-018042-qt7055fw	153	23	cells	cell	NNS
cord-018042-qt7055fw	153	24	.	.	.
cord-018042-qt7055fw	154	1	Although	although	IN
cord-018042-qt7055fw	154	2	it	-PRON-	PRP
cord-018042-qt7055fw	154	3	has	have	VBZ
cord-018042-qt7055fw	154	4	been	be	VBN
cord-018042-qt7055fw	154	5	possible	possible	JJ
cord-018042-qt7055fw	154	6	to	to	TO
cord-018042-qt7055fw	154	7	produce	produce	VB
cord-018042-qt7055fw	154	8	stimulus	stimulus	NN
cord-018042-qt7055fw	154	9	-	-	HYPH
cord-018042-qt7055fw	154	10	evoked	evoke	VBN
cord-018042-qt7055fw	154	11	encephalopathy	encephalopathy	NN
cord-018042-qt7055fw	154	12	in	in	IN
cord-018042-qt7055fw	154	13	MBP	MBP	NNP
cord-018042-qt7055fw	154	14	-	-	:
cord-018042-qt7055fw	154	15	and	and	CC
cord-018042-qt7055fw	154	16	GFAP	GFAP	NNP
cord-018042-qt7055fw	154	17	-	-	HYPH
cord-018042-qt7055fw	154	18	CCL2	CCL2	NNP
cord-018042-qt7055fw	154	19	transgenic	transgenic	JJ
cord-018042-qt7055fw	154	20	mice	mouse	NNS
cord-018042-qt7055fw	154	21	by	by	IN
cord-018042-qt7055fw	154	22	systemic	systemic	JJ
cord-018042-qt7055fw	154	23	innate	innate	JJ
cord-018042-qt7055fw	154	24	immune	immune	JJ
cord-018042-qt7055fw	154	25	challenge	challenge	NN
cord-018042-qt7055fw	154	26	these	these	DT
cord-018042-qt7055fw	154	27	disorders	disorder	NNS
cord-018042-qt7055fw	154	28	are	be	VBP
cord-018042-qt7055fw	154	29	largely	largely	RB
cord-018042-qt7055fw	154	30	transient	transient	JJ
cord-018042-qt7055fw	154	31	and	and	CC
cord-018042-qt7055fw	154	32	therefore	therefore	RB
cord-018042-qt7055fw	154	33	do	do	VBP
cord-018042-qt7055fw	154	34	not	not	RB
cord-018042-qt7055fw	154	35	model	model	VB
cord-018042-qt7055fw	154	36	the	the	DT
cord-018042-qt7055fw	154	37	increased	increase	VBN
cord-018042-qt7055fw	154	38	levels	level	NNS
cord-018042-qt7055fw	154	39	of	of	IN
cord-018042-qt7055fw	154	40	CNS	CNS	NNP
cord-018042-qt7055fw	154	41	CCL2	CCL2	NNP
cord-018042-qt7055fw	154	42	that	that	WDT
cord-018042-qt7055fw	154	43	have	have	VBP
cord-018042-qt7055fw	154	44	been	be	VBN
cord-018042-qt7055fw	154	45	reported	report	VBN
cord-018042-qt7055fw	154	46	to	to	TO
cord-018042-qt7055fw	154	47	occur	occur	VB
cord-018042-qt7055fw	154	48	in	in	IN
cord-018042-qt7055fw	154	49	chronic	chronic	JJ
cord-018042-qt7055fw	154	50	neurological	neurological	JJ
cord-018042-qt7055fw	154	51	diseases	disease	NNS
cord-018042-qt7055fw	154	52	such	such	JJ
cord-018042-qt7055fw	154	53	as	as	IN
cord-018042-qt7055fw	154	54	human	human	JJ
cord-018042-qt7055fw	154	55	immunodeficiency	immunodeficiency	NN
cord-018042-qt7055fw	154	56	virus	virus	NN
cord-018042-qt7055fw	154	57	type	type	NN
cord-018042-qt7055fw	154	58	1-associated	1-associated	CD
cord-018042-qt7055fw	154	59	dementia	dementia	NN
cord-018042-qt7055fw	154	60	,	,	,
cord-018042-qt7055fw	154	61	amyotrophic	amyotrophic	JJ
cord-018042-qt7055fw	154	62	lateral	lateral	JJ
cord-018042-qt7055fw	154	63	sclerosis	sclerosis	NN
cord-018042-qt7055fw	154	64	,	,	,
cord-018042-qt7055fw	154	65	and	and	CC
cord-018042-qt7055fw	154	66	multiple	multiple	JJ
cord-018042-qt7055fw	154	67	sclerosis	sclerosis	NN
cord-018042-qt7055fw	154	68	.	.	.
cord-018042-qt7055fw	155	1	However	however	RB
cord-018042-qt7055fw	155	2	,	,	,
cord-018042-qt7055fw	155	3	Huang	Huang	NNP
cord-018042-qt7055fw	155	4	et	et	NNP
cord-018042-qt7055fw	155	5	al	al	NNP
cord-018042-qt7055fw	155	6	.	.	.
cord-018042-qt7055fw	156	1	(	(	-LRB-
cord-018042-qt7055fw	156	2	2005	2005	CD
cord-018042-qt7055fw	156	3	)	)	-RRB-
cord-018042-qt7055fw	156	4	report	report	VBP
cord-018042-qt7055fw	156	5	from	from	IN
cord-018042-qt7055fw	156	6	a	a	DT
cord-018042-qt7055fw	156	7	more	more	RBR
cord-018042-qt7055fw	156	8	recent	recent	JJ
cord-018042-qt7055fw	156	9	study	study	NN
cord-018042-qt7055fw	156	10	that	that	IN
cord-018042-qt7055fw	156	11	GFAP	GFAP	NNP
cord-018042-qt7055fw	156	12	-	-	HYPH
cord-018042-qt7055fw	156	13	CCL2	CCL2	NNP
cord-018042-qt7055fw	156	14	transgenic	transgenic	JJ
cord-018042-qt7055fw	156	15	mice	mouse	NNS
cord-018042-qt7055fw	156	16	develop	develop	VBP
cord-018042-qt7055fw	156	17	a	a	DT
cord-018042-qt7055fw	156	18	spontaneous	spontaneous	JJ
cord-018042-qt7055fw	156	19	,	,	,
cord-018042-qt7055fw	156	20	delayed	delay	VBN
cord-018042-qt7055fw	156	21	encephalopathy	encephalopathy	NN
cord-018042-qt7055fw	156	22	from	from	IN
cord-018042-qt7055fw	156	23	>	>	XX
cord-018042-qt7055fw	156	24	7	7	CD
cord-018042-qt7055fw	156	25	months	month	NNS
cord-018042-qt7055fw	156	26	of	of	IN
cord-018042-qt7055fw	156	27	age	age	NN
cord-018042-qt7055fw	156	28	.	.	.
cord-018042-qt7055fw	157	1	These	these	DT
cord-018042-qt7055fw	157	2	mice	mouse	NNS
cord-018042-qt7055fw	157	3	presented	present	VBN
cord-018042-qt7055fw	157	4	with	with	IN
cord-018042-qt7055fw	157	5	loss	loss	NN
cord-018042-qt7055fw	157	6	of	of	IN
cord-018042-qt7055fw	157	7	weight	weight	NN
cord-018042-qt7055fw	157	8	,	,	,
cord-018042-qt7055fw	157	9	a	a	DT
cord-018042-qt7055fw	157	10	hunched	hunch	VBN
cord-018042-qt7055fw	157	11	posture	posture	NN
cord-018042-qt7055fw	157	12	,	,	,
cord-018042-qt7055fw	157	13	slow	slow	JJ
cord-018042-qt7055fw	157	14	response	response	NN
cord-018042-qt7055fw	157	15	to	to	IN
cord-018042-qt7055fw	157	16	tactile	tactile	JJ
cord-018042-qt7055fw	157	17	stimuli	stimulus	NNS
cord-018042-qt7055fw	157	18	and	and	CC
cord-018042-qt7055fw	157	19	a	a	DT
cord-018042-qt7055fw	157	20	flaccid	flaccid	JJ
cord-018042-qt7055fw	157	21	tail	tail	NN
cord-018042-qt7055fw	157	22	.	.	.
cord-018042-qt7055fw	158	1	Some	some	DT
cord-018042-qt7055fw	158	2	animals	animal	NNS
cord-018042-qt7055fw	158	3	even	even	RB
cord-018042-qt7055fw	158	4	developed	develop	VBD
cord-018042-qt7055fw	158	5	a	a	DT
cord-018042-qt7055fw	158	6	hind	hind	JJ
cord-018042-qt7055fw	158	7	-	-	HYPH
cord-018042-qt7055fw	158	8	limb	limb	NN
cord-018042-qt7055fw	158	9	paralysis	paralysis	NN
cord-018042-qt7055fw	158	10	at	at	IN
cord-018042-qt7055fw	158	11	>	>	$
cord-018042-qt7055fw	158	12	12	12	CD
cord-018042-qt7055fw	158	13	months	month	NNS
cord-018042-qt7055fw	158	14	of	of	IN
cord-018042-qt7055fw	158	15	age	age	NN
cord-018042-qt7055fw	158	16	.	.	.
cord-018042-qt7055fw	159	1	The	the	DT
cord-018042-qt7055fw	159	2	brain	brain	NN
cord-018042-qt7055fw	159	3	exhibited	exhibit	VBD
cord-018042-qt7055fw	159	4	perivascular	perivascular	NNP
cord-018042-qt7055fw	159	5	infiltrates	infiltrate	VBZ
cord-018042-qt7055fw	159	6	made	make	VBN
cord-018042-qt7055fw	159	7	up	up	RP
cord-018042-qt7055fw	159	8	of	of	IN
cord-018042-qt7055fw	159	9	activated	activate	VBN
cord-018042-qt7055fw	159	10	macrophages	macrophage	NNS
cord-018042-qt7055fw	159	11	,	,	,
cord-018042-qt7055fw	159	12	microglia	microglia	NNS
cord-018042-qt7055fw	159	13	with	with	IN
cord-018042-qt7055fw	159	14	morphological	morphological	JJ
cord-018042-qt7055fw	159	15	activation	activation	NN
cord-018042-qt7055fw	159	16	,	,	,
cord-018042-qt7055fw	159	17	and	and	CC
cord-018042-qt7055fw	159	18	impaired	impair	VBD
cord-018042-qt7055fw	159	19	BBB	BBB	NNP
cord-018042-qt7055fw	159	20	.	.	.
cord-018042-qt7055fw	160	1	Surprisingly	surprisingly	RB
cord-018042-qt7055fw	160	2	,	,	,
cord-018042-qt7055fw	160	3	no	no	DT
cord-018042-qt7055fw	160	4	evidence	evidence	NN
cord-018042-qt7055fw	160	5	was	be	VBD
cord-018042-qt7055fw	160	6	found	find	VBN
cord-018042-qt7055fw	160	7	for	for	IN
cord-018042-qt7055fw	160	8	demyelination	demyelination	NN
cord-018042-qt7055fw	160	9	or	or	CC
cord-018042-qt7055fw	160	10	of	of	IN
cord-018042-qt7055fw	160	11	reduced	reduce	VBN
cord-018042-qt7055fw	160	12	neurons	neuron	NNS
cord-018042-qt7055fw	160	13	,	,	,
cord-018042-qt7055fw	160	14	axons	axon	NNS
cord-018042-qt7055fw	160	15	,	,	,
cord-018042-qt7055fw	160	16	or	or	CC
cord-018042-qt7055fw	160	17	synapses	synapsis	NNS
cord-018042-qt7055fw	160	18	of	of	IN
cord-018042-qt7055fw	160	19	neural	neural	JJ
cord-018042-qt7055fw	160	20	components	component	NNS
cord-018042-qt7055fw	160	21	.	.	.
cord-018042-qt7055fw	161	1	Microglia	Microglia	NNP
cord-018042-qt7055fw	161	2	in	in	IN
cord-018042-qt7055fw	161	3	the	the	DT
cord-018042-qt7055fw	161	4	GFAP	GFAP	NNP
cord-018042-qt7055fw	161	5	-	-	HYPH
cord-018042-qt7055fw	161	6	CCL2	CCL2	NNP
cord-018042-qt7055fw	161	7	transgenic	transgenic	JJ
cord-018042-qt7055fw	161	8	mice	mouse	NNS
cord-018042-qt7055fw	161	9	,	,	,
cord-018042-qt7055fw	161	10	despite	despite	IN
cord-018042-qt7055fw	161	11	the	the	DT
cord-018042-qt7055fw	161	12	appearance	appearance	NN
cord-018042-qt7055fw	161	13	of	of	IN
cord-018042-qt7055fw	161	14	activation	activation	NN
cord-018042-qt7055fw	161	15	and	and	CC
cord-018042-qt7055fw	161	16	increased	increase	VBD
cord-018042-qt7055fw	161	17	CD45	CD45	NNP
cord-018042-qt7055fw	161	18	immunoreactivity	immunoreactivity	NN
cord-018042-qt7055fw	161	19	,	,	,
cord-018042-qt7055fw	161	20	were	be	VBD
cord-018042-qt7055fw	161	21	found	find	VBN
cord-018042-qt7055fw	161	22	to	to	TO
cord-018042-qt7055fw	161	23	be	be	VB
cord-018042-qt7055fw	161	24	defective	defective	JJ
cord-018042-qt7055fw	161	25	in	in	IN
cord-018042-qt7055fw	161	26	their	-PRON-	PRP$
cord-018042-qt7055fw	161	27	response	response	NN
cord-018042-qt7055fw	161	28	to	to	IN
cord-018042-qt7055fw	161	29	environmental	environmental	JJ
cord-018042-qt7055fw	161	30	stimuli	stimulus	NNS
cord-018042-qt7055fw	161	31	in	in	IN
cord-018042-qt7055fw	161	32	vitro	vitro	FW
cord-018042-qt7055fw	161	33	.	.	.
cord-018042-qt7055fw	162	1	The	the	DT
cord-018042-qt7055fw	162	2	Authors	author	NNS
cord-018042-qt7055fw	162	3	propose	propose	VBP
cord-018042-qt7055fw	162	4	that	that	IN
cord-018042-qt7055fw	162	5	chronic	chronic	JJ
cord-018042-qt7055fw	162	6	elevation	elevation	NN
cord-018042-qt7055fw	162	7	of	of	IN
cord-018042-qt7055fw	162	8	CCL2	CCL2	NNP
cord-018042-qt7055fw	162	9	in	in	IN
cord-018042-qt7055fw	162	10	the	the	DT
cord-018042-qt7055fw	162	11	CNS	CNS	NNP
cord-018042-qt7055fw	162	12	leads	lead	VBZ
cord-018042-qt7055fw	162	13	to	to	IN
cord-018042-qt7055fw	162	14	desensitization	desensitization	NN
cord-018042-qt7055fw	162	15	of	of	IN
cord-018042-qt7055fw	162	16	CCR2	CCR2	NNP
cord-018042-qt7055fw	162	17	and	and	CC
cord-018042-qt7055fw	162	18	microglial	microglial	JJ
cord-018042-qt7055fw	162	19	dysfunction	dysfunction	NN
cord-018042-qt7055fw	162	20	.	.	.
cord-018042-qt7055fw	163	1	Further	further	JJ
cord-018042-qt7055fw	163	2	support	support	NN
cord-018042-qt7055fw	163	3	for	for	IN
cord-018042-qt7055fw	163	4	the	the	DT
cord-018042-qt7055fw	163	5	notion	notion	NN
cord-018042-qt7055fw	163	6	that	that	IN
cord-018042-qt7055fw	163	7	chronic	chronic	JJ
cord-018042-qt7055fw	163	8	CCL2	CCL2	NNP
cord-018042-qt7055fw	163	9	leads	lead	VBZ
cord-018042-qt7055fw	163	10	to	to	IN
cord-018042-qt7055fw	163	11	microglial	microglial	JJ
cord-018042-qt7055fw	163	12	dysfunction	dysfunction	NN
cord-018042-qt7055fw	163	13	comes	come	VBZ
cord-018042-qt7055fw	163	14	from	from	IN
cord-018042-qt7055fw	163	15	a	a	DT
cord-018042-qt7055fw	163	16	study	study	NN
cord-018042-qt7055fw	163	17	by	by	IN
cord-018042-qt7055fw	163	18	Yamamoto	Yamamoto	NNP
cord-018042-qt7055fw	163	19	et	et	NNP
cord-018042-qt7055fw	163	20	al	al	NNP
cord-018042-qt7055fw	163	21	.	.	.
cord-018042-qt7055fw	164	1	who	who	WP
cord-018042-qt7055fw	164	2	generated	generate	VBD
cord-018042-qt7055fw	164	3	bigenic	bigenic	NNP
cord-018042-qt7055fw	164	4	GFAP	GFAP	NNP
cord-018042-qt7055fw	164	5	-	-	HYPH
cord-018042-qt7055fw	164	6	CCL2	CCL2	NNP
cord-018042-qt7055fw	164	7	/	/	SYM
cord-018042-qt7055fw	164	8	tg	tg	NNP
cord-018042-qt7055fw	164	9	2576	2576	CD
cord-018042-qt7055fw	164	10	mice	mouse	NNS
cord-018042-qt7055fw	164	11	that	that	WDT
cord-018042-qt7055fw	164	12	,	,	,
cord-018042-qt7055fw	164	13	in	in	IN
cord-018042-qt7055fw	164	14	addition	addition	NN
cord-018042-qt7055fw	164	15	to	to	IN
cord-018042-qt7055fw	164	16	chronic	chronic	JJ
cord-018042-qt7055fw	164	17	CCL2	CCL2	NNP
cord-018042-qt7055fw	164	18	,	,	,
cord-018042-qt7055fw	164	19	also	also	RB
cord-018042-qt7055fw	164	20	overproduce	overproduce	VB
cord-018042-qt7055fw	164	21	a	a	DT
cord-018042-qt7055fw	164	22	mutant	mutant	JJ
cord-018042-qt7055fw	164	23	amyloid	amyloid	NN
cord-018042-qt7055fw	164	24	precursor	precursor	NN
cord-018042-qt7055fw	164	25	protein	protein	NN
cord-018042-qt7055fw	164	26	(	(	-LRB-
cord-018042-qt7055fw	164	27	APP	app	NN
cord-018042-qt7055fw	164	28	)	)	-RRB-
cord-018042-qt7055fw	164	29	in	in	IN
cord-018042-qt7055fw	164	30	the	the	DT
cord-018042-qt7055fw	164	31	CNS	CNS	NNP
cord-018042-qt7055fw	165	1	(	(	-LRB-
cord-018042-qt7055fw	165	2	Yamamoto	Yamamoto	NNP
cord-018042-qt7055fw	165	3	et	et	NNP
cord-018042-qt7055fw	165	4	al	al	NNP
cord-018042-qt7055fw	165	5	.	.	NNP
cord-018042-qt7055fw	165	6	,	,	,
cord-018042-qt7055fw	165	7	2005	2005	CD
cord-018042-qt7055fw	165	8	)	)	-RRB-
cord-018042-qt7055fw	165	9	.	.	.
cord-018042-qt7055fw	166	1	These	these	DT
cord-018042-qt7055fw	166	2	workers	worker	NNS
cord-018042-qt7055fw	166	3	found	find	VBD
cord-018042-qt7055fw	166	4	a	a	DT
cord-018042-qt7055fw	166	5	significant	significant	JJ
cord-018042-qt7055fw	166	6	increase	increase	NN
cord-018042-qt7055fw	166	7	in	in	IN
cord-018042-qt7055fw	166	8	amyloid	amyloid	NN
cord-018042-qt7055fw	166	9	deposition	deposition	NN
cord-018042-qt7055fw	166	10	in	in	IN
cord-018042-qt7055fw	166	11	CCL2	CCL2	NNP
cord-018042-qt7055fw	166	12	/	/	SYM
cord-018042-qt7055fw	166	13	APP	app	NN
cord-018042-qt7055fw	166	14	bigenic	bigenic	JJ
cord-018042-qt7055fw	166	15	mice	mouse	NNS
cord-018042-qt7055fw	166	16	compared	compare	VBN
cord-018042-qt7055fw	166	17	with	with	IN
cord-018042-qt7055fw	166	18	APP	app	NN
cord-018042-qt7055fw	166	19	singly	singly	RB
cord-018042-qt7055fw	166	20	transgenic	transgenic	JJ
cord-018042-qt7055fw	166	21	mice	mouse	NNS
cord-018042-qt7055fw	166	22	.	.	.
cord-018042-qt7055fw	167	1	Despite	despite	IN
cord-018042-qt7055fw	167	2	being	be	VBG
cord-018042-qt7055fw	167	3	accompanied	accompany	VBN
cord-018042-qt7055fw	167	4	by	by	IN
cord-018042-qt7055fw	167	5	an	an	DT
cord-018042-qt7055fw	167	6	increase	increase	NN
cord-018042-qt7055fw	167	7	in	in	IN
cord-018042-qt7055fw	167	8	lesion	lesion	NN
cord-018042-qt7055fw	167	9	-	-	HYPH
cord-018042-qt7055fw	167	10	associated	associate	VBN
cord-018042-qt7055fw	167	11	macrophages	macrophage	NNS
cord-018042-qt7055fw	167	12	/	/	SYM
cord-018042-qt7055fw	167	13	microglia	microglia	NNS
cord-018042-qt7055fw	167	14	,	,	,
cord-018042-qt7055fw	167	15	evidence	evidence	NN
cord-018042-qt7055fw	167	16	is	be	VBZ
cord-018042-qt7055fw	167	17	provided	provide	VBN
cord-018042-qt7055fw	167	18	suggesting	suggest	VBG
cord-018042-qt7055fw	167	19	that	that	IN
cord-018042-qt7055fw	167	20	these	these	DT
cord-018042-qt7055fw	167	21	cells	cell	NNS
cord-018042-qt7055fw	167	22	show	show	VBP
cord-018042-qt7055fw	167	23	reduced	reduce	VBN
cord-018042-qt7055fw	167	24	phagocytic	phagocytic	JJ
cord-018042-qt7055fw	167	25	function	function	NN
cord-018042-qt7055fw	167	26	leading	lead	VBG
cord-018042-qt7055fw	167	27	to	to	IN
cord-018042-qt7055fw	167	28	accelerated	accelerated	JJ
cord-018042-qt7055fw	167	29	amyloid	amyloid	NN
cord-018042-qt7055fw	167	30	deposition	deposition	NN
cord-018042-qt7055fw	167	31	.	.	.
cord-018042-qt7055fw	168	1	These	these	DT
cord-018042-qt7055fw	168	2	findings	finding	NNS
cord-018042-qt7055fw	168	3	underline	underline	VBP
cord-018042-qt7055fw	168	4	the	the	DT
cord-018042-qt7055fw	168	5	importance	importance	NN
cord-018042-qt7055fw	168	6	of	of	IN
cord-018042-qt7055fw	168	7	considering	consider	VBG
cord-018042-qt7055fw	168	8	the	the	DT
cord-018042-qt7055fw	168	9	participation	participation	NN
cord-018042-qt7055fw	168	10	of	of	IN
cord-018042-qt7055fw	168	11	chemokines	chemokine	NNS
cord-018042-qt7055fw	168	12	and	and	CC
cord-018042-qt7055fw	168	13	chemokine	chemokine	NN
cord-018042-qt7055fw	168	14	driven	drive	VBN
cord-018042-qt7055fw	168	15	monocyte	monocyte	NNP
cord-018042-qt7055fw	168	16	accumulation	accumulation	NN
cord-018042-qt7055fw	168	17	and	and	CC
cord-018042-qt7055fw	168	18	function	function	NN
cord-018042-qt7055fw	168	19	in	in	IN
cord-018042-qt7055fw	168	20	the	the	DT
cord-018042-qt7055fw	168	21	pathogenesis	pathogenesis	NN
cord-018042-qt7055fw	168	22	of	of	IN
cord-018042-qt7055fw	168	23	degenerative	degenerative	JJ
cord-018042-qt7055fw	168	24	CNS	CNS	NNP
cord-018042-qt7055fw	168	25	diseases	disease	NNS
cord-018042-qt7055fw	168	26	.	.	.
cord-018042-qt7055fw	169	1	The	the	DT
cord-018042-qt7055fw	169	2	chemokines	chemokine	NNS
cord-018042-qt7055fw	169	3	CCL19	CCL19	NNP
cord-018042-qt7055fw	169	4	and	and	CC
cord-018042-qt7055fw	169	5	CCL21	CCL21	NNP
cord-018042-qt7055fw	169	6	have	have	VBP
cord-018042-qt7055fw	169	7	been	be	VBN
cord-018042-qt7055fw	169	8	implicated	implicate	VBN
cord-018042-qt7055fw	169	9	in	in	IN
cord-018042-qt7055fw	169	10	the	the	DT
cord-018042-qt7055fw	169	11	migration	migration	NN
cord-018042-qt7055fw	169	12	of	of	IN
cord-018042-qt7055fw	169	13	lymphocytes	lymphocyte	NNS
cord-018042-qt7055fw	169	14	and	and	CC
cord-018042-qt7055fw	169	15	are	be	VBP
cord-018042-qt7055fw	169	16	produced	produce	VBN
cord-018042-qt7055fw	169	17	in	in	IN
cord-018042-qt7055fw	169	18	secondary	secondary	JJ
cord-018042-qt7055fw	169	19	lymphoid	lymphoid	JJ
cord-018042-qt7055fw	169	20	organs	organ	NNS
cord-018042-qt7055fw	169	21	such	such	JJ
cord-018042-qt7055fw	169	22	as	as	IN
cord-018042-qt7055fw	169	23	the	the	DT
cord-018042-qt7055fw	169	24	lymph	lymph	NN
cord-018042-qt7055fw	169	25	nodes	node	NNS
cord-018042-qt7055fw	169	26	.	.	.
cord-018042-qt7055fw	170	1	Both	both	CC
cord-018042-qt7055fw	170	2	these	these	DT
cord-018042-qt7055fw	170	3	chemokines	chemokine	NNS
cord-018042-qt7055fw	170	4	bind	bind	VBP
cord-018042-qt7055fw	170	5	to	to	IN
cord-018042-qt7055fw	170	6	CCR7	CCR7	NNP
cord-018042-qt7055fw	170	7	and	and	CC
cord-018042-qt7055fw	170	8	CCR11	CCR11	NNP
cord-018042-qt7055fw	170	9	.	.	.
cord-018042-qt7055fw	171	1	Mice	mouse	NNS
cord-018042-qt7055fw	171	2	lacking	lack	VBG
cord-018042-qt7055fw	172	1	CCR7	CCR7	NNS
cord-018042-qt7055fw	172	2	have	have	VBP
cord-018042-qt7055fw	172	3	impaired	impair	VBN
cord-018042-qt7055fw	172	4	migration	migration	NN
cord-018042-qt7055fw	172	5	of	of	IN
cord-018042-qt7055fw	172	6	lymphocytes	lymphocyte	NNS
cord-018042-qt7055fw	172	7	into	into	IN
cord-018042-qt7055fw	172	8	secondary	secondary	JJ
cord-018042-qt7055fw	172	9	lymphoid	lymphoid	JJ
cord-018042-qt7055fw	172	10	organs	organ	NNS
cord-018042-qt7055fw	172	11	(	(	-LRB-
cord-018042-qt7055fw	172	12	Forster	Forster	NNP
cord-018042-qt7055fw	172	13	et	et	NNP
cord-018042-qt7055fw	172	14	al	al	NNP
cord-018042-qt7055fw	172	15	.	.	NNP
cord-018042-qt7055fw	172	16	,	,	,
cord-018042-qt7055fw	172	17	1999	1999	CD
cord-018042-qt7055fw	172	18	)	)	-RRB-
cord-018042-qt7055fw	172	19	.	.	.
cord-018042-qt7055fw	173	1	CCL21	CCL21	NNP
cord-018042-qt7055fw	173	2	but	but	CC
cord-018042-qt7055fw	173	3	not	not	RB
cord-018042-qt7055fw	173	4	CCL19	CCL19	NNP
cord-018042-qt7055fw	173	5	has	have	VBZ
cord-018042-qt7055fw	173	6	also	also	RB
cord-018042-qt7055fw	173	7	been	be	VBN
cord-018042-qt7055fw	173	8	reported	report	VBN
cord-018042-qt7055fw	173	9	to	to	TO
cord-018042-qt7055fw	173	10	bind	bind	VB
cord-018042-qt7055fw	173	11	to	to	IN
cord-018042-qt7055fw	173	12	CXCR3	cxcr3	XX
cord-018042-qt7055fw	174	1	(	(	-LRB-
cord-018042-qt7055fw	174	2	Rappert	Rappert	NNP
cord-018042-qt7055fw	174	3	et	et	NNP
cord-018042-qt7055fw	174	4	al	al	NNP
cord-018042-qt7055fw	174	5	.	.	NNP
cord-018042-qt7055fw	174	6	,	,	,
cord-018042-qt7055fw	174	7	2002	2002	CD
cord-018042-qt7055fw	174	8	)	)	-RRB-
cord-018042-qt7055fw	174	9	.	.	.
cord-018042-qt7055fw	175	1	CCL19	CCL19	NNP
cord-018042-qt7055fw	175	2	and	and	CC
cord-018042-qt7055fw	175	3	CCL21	CCL21	NNP
cord-018042-qt7055fw	175	4	are	be	VBP
cord-018042-qt7055fw	175	5	localized	localize	VBN
cord-018042-qt7055fw	175	6	in	in	IN
cord-018042-qt7055fw	175	7	venules	venule	NNS
cord-018042-qt7055fw	175	8	surrounded	surround	VBN
cord-018042-qt7055fw	175	9	by	by	IN
cord-018042-qt7055fw	175	10	CCR7	CCR7	NNP
cord-018042-qt7055fw	175	11	positive	positive	JJ
cord-018042-qt7055fw	175	12	inflammatory	inflammatory	JJ
cord-018042-qt7055fw	175	13	cells	cell	NNS
cord-018042-qt7055fw	175	14	in	in	IN
cord-018042-qt7055fw	175	15	the	the	DT
cord-018042-qt7055fw	175	16	brain	brain	NN
cord-018042-qt7055fw	175	17	and	and	CC
cord-018042-qt7055fw	175	18	spinal	spinal	JJ
cord-018042-qt7055fw	175	19	cord	cord	NN
cord-018042-qt7055fw	175	20	of	of	IN
cord-018042-qt7055fw	175	21	mice	mouse	NNS
cord-018042-qt7055fw	175	22	with	with	IN
cord-018042-qt7055fw	175	23	EAE	EAE	NNP
cord-018042-qt7055fw	175	24	and	and	CC
cord-018042-qt7055fw	175	25	functional	functional	JJ
cord-018042-qt7055fw	175	26	studies	study	NNS
cord-018042-qt7055fw	175	27	suggest	suggest	VBP
cord-018042-qt7055fw	175	28	that	that	IN
cord-018042-qt7055fw	175	29	CCL19	CCL19	NNP
cord-018042-qt7055fw	175	30	and	and	CC
cord-018042-qt7055fw	175	31	CCL21	CCL21	NNP
cord-018042-qt7055fw	175	32	are	be	VBP
cord-018042-qt7055fw	175	33	involved	involve	VBN
cord-018042-qt7055fw	175	34	in	in	IN
cord-018042-qt7055fw	175	35	T	T	NNP
cord-018042-qt7055fw	175	36	lymphocyte	lymphocyte	NN
cord-018042-qt7055fw	175	37	migration	migration	NN
cord-018042-qt7055fw	175	38	into	into	IN
cord-018042-qt7055fw	175	39	the	the	DT
cord-018042-qt7055fw	175	40	central	central	JJ
cord-018042-qt7055fw	175	41	nervous	nervous	JJ
cord-018042-qt7055fw	175	42	system	system	NN
cord-018042-qt7055fw	175	43	during	during	IN
cord-018042-qt7055fw	175	44	EAE	EAE	NNP
cord-018042-qt7055fw	175	45	(	(	-LRB-
cord-018042-qt7055fw	175	46	Alt	Alt	NNP
cord-018042-qt7055fw	175	47	et	et	FW
cord-018042-qt7055fw	175	48	al	al	NNP
cord-018042-qt7055fw	175	49	.	.	NNP
cord-018042-qt7055fw	175	50	,	,	,
cord-018042-qt7055fw	175	51	2002	2002	CD
cord-018042-qt7055fw	175	52	)	)	-RRB-
cord-018042-qt7055fw	175	53	.	.	.
cord-018042-qt7055fw	176	1	However	however	RB
cord-018042-qt7055fw	176	2	,	,	,
cord-018042-qt7055fw	176	3	recent	recent	JJ
cord-018042-qt7055fw	176	4	studies	study	NNS
cord-018042-qt7055fw	176	5	in	in	IN
cord-018042-qt7055fw	176	6	CCR7	CCR7	NNP
cord-018042-qt7055fw	176	7	deficient	deficient	JJ
cord-018042-qt7055fw	176	8	mice	mouse	NNS
cord-018042-qt7055fw	176	9	suggest	suggest	VBP
cord-018042-qt7055fw	176	10	that	that	IN
cord-018042-qt7055fw	176	11	CCL19	CCL19	NNP
cord-018042-qt7055fw	176	12	and	and	CC
cord-018042-qt7055fw	176	13	CCL21	CCL21	NNP
cord-018042-qt7055fw	176	14	function	function	NN
cord-018042-qt7055fw	176	15	may	may	MD
cord-018042-qt7055fw	176	16	be	be	VB
cord-018042-qt7055fw	176	17	dispensable	dispensable	JJ
cord-018042-qt7055fw	176	18	in	in	IN
cord-018042-qt7055fw	176	19	EAE	EAE	NNP
cord-018042-qt7055fw	176	20	(	(	-LRB-
cord-018042-qt7055fw	176	21	Pahuja	Pahuja	NNP
cord-018042-qt7055fw	176	22	et	et	NNP
cord-018042-qt7055fw	176	23	al	al	NNP
cord-018042-qt7055fw	176	24	.	.	NNP
cord-018042-qt7055fw	176	25	,	,	,
cord-018042-qt7055fw	176	26	2006	2006	CD
cord-018042-qt7055fw	176	27	)	)	-RRB-
cord-018042-qt7055fw	176	28	.	.	.
cord-018042-qt7055fw	177	1	This	this	DT
cord-018042-qt7055fw	177	2	interpretation	interpretation	NN
cord-018042-qt7055fw	177	3	is	be	VBZ
cord-018042-qt7055fw	177	4	complicated	complicate	VBN
cord-018042-qt7055fw	177	5	in	in	IN
cord-018042-qt7055fw	177	6	the	the	DT
cord-018042-qt7055fw	177	7	case	case	NN
cord-018042-qt7055fw	177	8	of	of	IN
cord-018042-qt7055fw	177	9	CCL21	CCL21	NNP
cord-018042-qt7055fw	177	10	since	since	IN
cord-018042-qt7055fw	177	11	this	this	DT
cord-018042-qt7055fw	177	12	chemokine	chemokine	NN
cord-018042-qt7055fw	177	13	could	could	MD
cord-018042-qt7055fw	177	14	still	still	RB
cord-018042-qt7055fw	177	15	play	play	VB
cord-018042-qt7055fw	177	16	a	a	DT
cord-018042-qt7055fw	177	17	role	role	NN
cord-018042-qt7055fw	177	18	in	in	IN
cord-018042-qt7055fw	177	19	EAE	EAE	NNP
cord-018042-qt7055fw	177	20	in	in	IN
cord-018042-qt7055fw	177	21	CCR7	CCR7	NNP
cord-018042-qt7055fw	177	22	deficient	deficient	JJ
cord-018042-qt7055fw	177	23	mice	mouse	NNS
cord-018042-qt7055fw	177	24	via	via	IN
cord-018042-qt7055fw	177	25	CXCR3	CXCR3	NNP
cord-018042-qt7055fw	177	26	on	on	IN
cord-018042-qt7055fw	177	27	encephalitogenic	encephalitogenic	NNP
cord-018042-qt7055fw	177	28	T	T	NNP
cord-018042-qt7055fw	177	29	-	-	HYPH
cord-018042-qt7055fw	177	30	cells	cell	NNS
cord-018042-qt7055fw	177	31	.	.	.
cord-018042-qt7055fw	178	1	Moreover	moreover	RB
cord-018042-qt7055fw	178	2	,	,	,
cord-018042-qt7055fw	178	3	CCL21	CCL21	NNP
cord-018042-qt7055fw	178	4	was	be	VBD
cord-018042-qt7055fw	178	5	reported	report	VBN
cord-018042-qt7055fw	178	6	to	to	TO
cord-018042-qt7055fw	178	7	be	be	VB
cord-018042-qt7055fw	178	8	produced	produce	VBN
cord-018042-qt7055fw	178	9	by	by	IN
cord-018042-qt7055fw	178	10	neurons	neuron	NNS
cord-018042-qt7055fw	178	11	in	in	IN
cord-018042-qt7055fw	178	12	the	the	DT
cord-018042-qt7055fw	178	13	murine	murine	JJ
cord-018042-qt7055fw	178	14	brain	brain	NN
cord-018042-qt7055fw	178	15	following	follow	VBG
cord-018042-qt7055fw	178	16	ischemic	ischemic	JJ
cord-018042-qt7055fw	178	17	insult	insult	NN
cord-018042-qt7055fw	178	18	,	,	,
cord-018042-qt7055fw	178	19	highlighting	highlight	VBG
cord-018042-qt7055fw	178	20	the	the	DT
cord-018042-qt7055fw	178	21	existence	existence	NN
cord-018042-qt7055fw	178	22	of	of	IN
cord-018042-qt7055fw	178	23	an	an	DT
cord-018042-qt7055fw	178	24	intrinsic	intrinsic	JJ
cord-018042-qt7055fw	178	25	source	source	NN
cord-018042-qt7055fw	178	26	of	of	IN
cord-018042-qt7055fw	178	27	this	this	DT
cord-018042-qt7055fw	178	28	chemokine	chemokine	NN
cord-018042-qt7055fw	178	29	in	in	IN
cord-018042-qt7055fw	178	30	the	the	DT
cord-018042-qt7055fw	178	31	CNS	CNS	NNP
cord-018042-qt7055fw	178	32	that	that	WDT
cord-018042-qt7055fw	178	33	could	could	MD
cord-018042-qt7055fw	178	34	interact	interact	VB
cord-018042-qt7055fw	178	35	with	with	IN
cord-018042-qt7055fw	178	36	microglia	microglia	NN
cord-018042-qt7055fw	178	37	via	via	IN
cord-018042-qt7055fw	178	38	CXCR3	cxcr3	NN
cord-018042-qt7055fw	178	39	.	.	.
cord-018042-qt7055fw	179	1	To	to	TO
cord-018042-qt7055fw	179	2	study	study	VB
cord-018042-qt7055fw	179	3	the	the	DT
cord-018042-qt7055fw	179	4	biological	biological	JJ
cord-018042-qt7055fw	179	5	role	role	NN
cord-018042-qt7055fw	179	6	of	of	IN
cord-018042-qt7055fw	179	7	the	the	DT
cord-018042-qt7055fw	179	8	chemokine	chemokine	NN
cord-018042-qt7055fw	179	9	ligands	ligand	NNS
cord-018042-qt7055fw	179	10	CCL19	CCL19	NNP
cord-018042-qt7055fw	179	11	and	and	CC
cord-018042-qt7055fw	179	12	CCL21	CCL21	NNP
cord-018042-qt7055fw	179	13	,	,	,
cord-018042-qt7055fw	179	14	transgenic	transgenic	JJ
cord-018042-qt7055fw	179	15	mice	mouse	NNS
cord-018042-qt7055fw	179	16	were	be	VBD
cord-018042-qt7055fw	179	17	developed	develop	VBN
cord-018042-qt7055fw	179	18	that	that	WDT
cord-018042-qt7055fw	179	19	expressed	express	VBN
cord-018042-qt7055fw	179	20	either	either	CC
cord-018042-qt7055fw	179	21	CCL19	CCL19	NNP
cord-018042-qt7055fw	179	22	or	or	CC
cord-018042-qt7055fw	179	23	CCL21	CCL21	NNP
cord-018042-qt7055fw	179	24	in	in	IN
cord-018042-qt7055fw	179	25	oligodendrocytes	oligodendrocyte	NNS
cord-018042-qt7055fw	179	26	of	of	IN
cord-018042-qt7055fw	179	27	the	the	DT
cord-018042-qt7055fw	179	28	CNS	CNS	NNP
cord-018042-qt7055fw	179	29	using	use	VBG
cord-018042-qt7055fw	179	30	an	an	DT
cord-018042-qt7055fw	179	31	MBP	MBP	NNP
cord-018042-qt7055fw	179	32	-	-	HYPH
cord-018042-qt7055fw	179	33	promoter	promoter	NN
cord-018042-qt7055fw	179	34	construct	construct	NN
cord-018042-qt7055fw	179	35	(	(	-LRB-
cord-018042-qt7055fw	180	1	Chen	Chen	NNP
cord-018042-qt7055fw	180	2	et	et	NNP
cord-018042-qt7055fw	180	3	al	al	NNP
cord-018042-qt7055fw	180	4	.	.	NNP
cord-018042-qt7055fw	180	5	,	,	,
cord-018042-qt7055fw	180	6	2002a	2002a	CD
cord-018042-qt7055fw	180	7	)	)	-RRB-
cord-018042-qt7055fw	180	8	.	.	.
cord-018042-qt7055fw	181	1	As	as	IN
cord-018042-qt7055fw	181	2	expected	expect	VBN
cord-018042-qt7055fw	181	3	,	,	,
cord-018042-qt7055fw	181	4	transgene	transgene	NN
cord-018042-qt7055fw	181	5	-	-	HYPH
cord-018042-qt7055fw	181	6	encoded	encode	VBN
cord-018042-qt7055fw	181	7	CCL19	CCL19	NNP
cord-018042-qt7055fw	181	8	and	and	CC
cord-018042-qt7055fw	181	9	CCL20	CCL20	NNP
cord-018042-qt7055fw	181	10	mRNA	mRNA	NNP
cord-018042-qt7055fw	181	11	was	be	VBD
cord-018042-qt7055fw	181	12	developmentally	developmentally	RB
cord-018042-qt7055fw	181	13	regulated	regulate	VBN
cord-018042-qt7055fw	181	14	and	and	CC
cord-018042-qt7055fw	181	15	peaked	peak	VBD
cord-018042-qt7055fw	181	16	at	at	IN
cord-018042-qt7055fw	181	17	2	2	CD
cord-018042-qt7055fw	181	18	-	-	SYM
cord-018042-qt7055fw	181	19	3	3	CD
cord-018042-qt7055fw	181	20	weeks	week	NNS
cord-018042-qt7055fw	181	21	of	of	IN
cord-018042-qt7055fw	181	22	age	age	NN
cord-018042-qt7055fw	181	23	.	.	.
cord-018042-qt7055fw	182	1	Expression	expression	NN
cord-018042-qt7055fw	182	2	of	of	IN
cord-018042-qt7055fw	182	3	CCL19	CCL19	NNP
cord-018042-qt7055fw	182	4	or	or	CC
cord-018042-qt7055fw	182	5	CCL21	CCL21	NNP
cord-018042-qt7055fw	182	6	protein	protein	NN
cord-018042-qt7055fw	182	7	in	in	IN
cord-018042-qt7055fw	182	8	the	the	DT
cord-018042-qt7055fw	182	9	CNS	CNS	NNP
cord-018042-qt7055fw	182	10	of	of	IN
cord-018042-qt7055fw	182	11	the	the	DT
cord-018042-qt7055fw	182	12	transgenic	transgenic	JJ
cord-018042-qt7055fw	182	13	mice	mouse	NNS
cord-018042-qt7055fw	182	14	was	be	VBD
cord-018042-qt7055fw	182	15	confirmed	confirm	VBN
cord-018042-qt7055fw	182	16	by	by	IN
cord-018042-qt7055fw	182	17	immunohistochemical	immunohistochemical	JJ
cord-018042-qt7055fw	182	18	staining	staining	NN
cord-018042-qt7055fw	182	19	.	.	.
cord-018042-qt7055fw	183	1	CCL19	CCL19	NNP
cord-018042-qt7055fw	183	2	producing	produce	VBG
cord-018042-qt7055fw	183	3	transgenic	transgenic	JJ
cord-018042-qt7055fw	183	4	mice	mouse	NNS
cord-018042-qt7055fw	183	5	did	do	VBD
cord-018042-qt7055fw	183	6	not	not	RB
cord-018042-qt7055fw	183	7	show	show	VB
cord-018042-qt7055fw	183	8	any	any	DT
cord-018042-qt7055fw	183	9	clinical	clinical	JJ
cord-018042-qt7055fw	183	10	or	or	CC
cord-018042-qt7055fw	183	11	histological	histological	JJ
cord-018042-qt7055fw	183	12	phenotype	phenotype	NN
cord-018042-qt7055fw	183	13	,	,	,
cord-018042-qt7055fw	183	14	which	which	WDT
cord-018042-qt7055fw	183	15	led	lead	VBD
cord-018042-qt7055fw	183	16	to	to	IN
cord-018042-qt7055fw	183	17	the	the	DT
cord-018042-qt7055fw	183	18	conclusion	conclusion	NN
cord-018042-qt7055fw	183	19	that	that	IN
cord-018042-qt7055fw	183	20	CCL19	CCL19	NNP
cord-018042-qt7055fw	183	21	,	,	,
cord-018042-qt7055fw	183	22	at	at	IN
cord-018042-qt7055fw	183	23	least	least	JJS
cord-018042-qt7055fw	183	24	from	from	IN
cord-018042-qt7055fw	183	25	diffuse	diffuse	JJ
cord-018042-qt7055fw	183	26	cerebral	cerebral	JJ
cord-018042-qt7055fw	183	27	expression	expression	NN
cord-018042-qt7055fw	183	28	,	,	,
cord-018042-qt7055fw	183	29	is	be	VBZ
cord-018042-qt7055fw	183	30	not	not	RB
cord-018042-qt7055fw	183	31	able	able	JJ
cord-018042-qt7055fw	183	32	to	to	TO
cord-018042-qt7055fw	183	33	attract	attract	VB
cord-018042-qt7055fw	183	34	leukocytes	leukocyte	NNS
cord-018042-qt7055fw	183	35	into	into	IN
cord-018042-qt7055fw	183	36	the	the	DT
cord-018042-qt7055fw	183	37	brain	brain	NN
cord-018042-qt7055fw	183	38	or	or	CC
cord-018042-qt7055fw	183	39	cause	cause	VB
cord-018042-qt7055fw	183	40	a	a	DT
cord-018042-qt7055fw	183	41	CNS	CNS	NNP
cord-018042-qt7055fw	183	42	pathology	pathology	NN
cord-018042-qt7055fw	183	43	.	.	.
cord-018042-qt7055fw	184	1	In	in	IN
cord-018042-qt7055fw	184	2	contrast	contrast	NN
cord-018042-qt7055fw	184	3	,	,	,
cord-018042-qt7055fw	184	4	transgenic	transgenic	JJ
cord-018042-qt7055fw	184	5	mice	mouse	NNS
cord-018042-qt7055fw	184	6	with	with	IN
cord-018042-qt7055fw	184	7	MBP	MBP	NNP
cord-018042-qt7055fw	184	8	-	-	HYPH
cord-018042-qt7055fw	184	9	promoter	promoter	NN
cord-018042-qt7055fw	184	10	driven	drive	VBN
cord-018042-qt7055fw	184	11	production	production	NN
cord-018042-qt7055fw	184	12	of	of	IN
cord-018042-qt7055fw	184	13	CCL21	CCL21	NNP
cord-018042-qt7055fw	184	14	developed	develop	VBD
cord-018042-qt7055fw	184	15	a	a	DT
cord-018042-qt7055fw	184	16	rapid	rapid	JJ
cord-018042-qt7055fw	184	17	onset	onset	NN
cord-018042-qt7055fw	184	18	encephalopathy	encephalopathy	NN
cord-018042-qt7055fw	184	19	with	with	IN
cord-018042-qt7055fw	184	20	tremor	tremor	NN
cord-018042-qt7055fw	184	21	,	,	,
cord-018042-qt7055fw	184	22	ataxia	ataxia	NN
cord-018042-qt7055fw	184	23	and	and	CC
cord-018042-qt7055fw	184	24	weight	weight	NN
cord-018042-qt7055fw	184	25	loss	loss	NN
cord-018042-qt7055fw	184	26	.	.	.
cord-018042-qt7055fw	185	1	Most	Most	JJS
cord-018042-qt7055fw	185	2	of	of	IN
cord-018042-qt7055fw	185	3	the	the	DT
cord-018042-qt7055fw	185	4	CCL21	CCL21	NNP
cord-018042-qt7055fw	185	5	producing	produce	VBG
cord-018042-qt7055fw	185	6	animals	animal	NNS
cord-018042-qt7055fw	185	7	died	die	VBD
cord-018042-qt7055fw	185	8	within	within	IN
cord-018042-qt7055fw	185	9	4	4	CD
cord-018042-qt7055fw	185	10	weeks	week	NNS
cord-018042-qt7055fw	185	11	.	.	.
cord-018042-qt7055fw	186	1	Studies	study	NNS
cord-018042-qt7055fw	186	2	in	in	IN
cord-018042-qt7055fw	186	3	vitro	vitro	FW
cord-018042-qt7055fw	186	4	documented	document	VBD
cord-018042-qt7055fw	186	5	a	a	DT
cord-018042-qt7055fw	186	6	chemotactic	chemotactic	JJ
cord-018042-qt7055fw	186	7	effect	effect	NN
cord-018042-qt7055fw	186	8	of	of	IN
cord-018042-qt7055fw	186	9	CCL21	CCL21	NNP
cord-018042-qt7055fw	186	10	for	for	IN
cord-018042-qt7055fw	186	11	thymocytes	thymocyte	NNS
cord-018042-qt7055fw	186	12	,	,	,
cord-018042-qt7055fw	186	13	naïve	naïve	JJ
cord-018042-qt7055fw	186	14	T	T	NNP
cord-018042-qt7055fw	186	15	cells	cell	NNS
cord-018042-qt7055fw	186	16	,	,	,
cord-018042-qt7055fw	186	17	dendritic	dendritic	JJ
cord-018042-qt7055fw	186	18	cells	cell	NNS
cord-018042-qt7055fw	186	19	and	and	CC
cord-018042-qt7055fw	186	20	B	b	NN
cord-018042-qt7055fw	186	21	cells	cell	NNS
cord-018042-qt7055fw	186	22	and	and	CC
cord-018042-qt7055fw	186	23	not	not	RB
cord-018042-qt7055fw	186	24	for	for	IN
cord-018042-qt7055fw	186	25	macrophages	macrophage	NNS
cord-018042-qt7055fw	186	26	and	and	CC
cord-018042-qt7055fw	186	27	neutrophils	neutrophil	NNS
cord-018042-qt7055fw	186	28	(	(	-LRB-
cord-018042-qt7055fw	186	29	Hedrick	Hedrick	NNP
cord-018042-qt7055fw	186	30	and	and	CC
cord-018042-qt7055fw	186	31	Zlotnik	Zlotnik	NNP
cord-018042-qt7055fw	186	32	,	,	,
cord-018042-qt7055fw	186	33	1997	1997	CD
cord-018042-qt7055fw	186	34	;	;	.
cord-018042-qt7055fw	187	1	Nagira	Nagira	NNP
cord-018042-qt7055fw	187	2	et	et	FW
cord-018042-qt7055fw	187	3	al	al	NNP
cord-018042-qt7055fw	187	4	.	.	.
cord-018042-qt7055fw	188	1	,	,	,
cord-018042-qt7055fw	188	2	1997	1997	CD
cord-018042-qt7055fw	188	3	;	;	:
cord-018042-qt7055fw	188	4	Kellermann	Kellermann	NNP
cord-018042-qt7055fw	188	5	et	et	NNP
cord-018042-qt7055fw	188	6	al	al	NNP
cord-018042-qt7055fw	188	7	.	.	NNP
cord-018042-qt7055fw	188	8	,	,	,
cord-018042-qt7055fw	188	9	1999	1999	CD
cord-018042-qt7055fw	188	10	)	)	-RRB-
cord-018042-qt7055fw	188	11	.	.	.
cord-018042-qt7055fw	189	1	However	however	RB
cord-018042-qt7055fw	189	2	,	,	,
cord-018042-qt7055fw	189	3	cerebral	cerebral	JJ
cord-018042-qt7055fw	189	4	infiltrates	infiltrate	VBZ
cord-018042-qt7055fw	189	5	in	in	IN
cord-018042-qt7055fw	189	6	CCL21	CCL21	NNP
cord-018042-qt7055fw	189	7	producing	produce	VBG
cord-018042-qt7055fw	189	8	transgenic	transgenic	JJ
cord-018042-qt7055fw	189	9	mice	mouse	NNS
cord-018042-qt7055fw	189	10	consisted	consist	VBD
cord-018042-qt7055fw	189	11	almost	almost	RB
cord-018042-qt7055fw	189	12	exclusively	exclusively	RB
cord-018042-qt7055fw	189	13	of	of	IN
cord-018042-qt7055fw	189	14	neutrophils	neutrophil	NNS
cord-018042-qt7055fw	189	15	and	and	CC
cord-018042-qt7055fw	189	16	eosinophils	eosinophil	NNS
cord-018042-qt7055fw	189	17	.	.	.
cord-018042-qt7055fw	190	1	These	these	DT
cord-018042-qt7055fw	190	2	infiltrates	infiltrate	NNS
cord-018042-qt7055fw	190	3	were	be	VBD
cord-018042-qt7055fw	190	4	associated	associate	VBN
cord-018042-qt7055fw	190	5	with	with	IN
cord-018042-qt7055fw	190	6	gliosis	gliosis	NNP
cord-018042-qt7055fw	190	7	,	,	,
cord-018042-qt7055fw	190	8	microglial	microglial	JJ
cord-018042-qt7055fw	190	9	activation	activation	NN
cord-018042-qt7055fw	190	10	and	and	CC
cord-018042-qt7055fw	190	11	demyelination	demyelination	NN
cord-018042-qt7055fw	190	12	.	.	.
cord-018042-qt7055fw	191	1	Infiltrating	infiltrate	VBG
cord-018042-qt7055fw	191	2	lymphocytes	lymphocyte	NNS
cord-018042-qt7055fw	191	3	were	be	VBD
cord-018042-qt7055fw	191	4	not	not	RB
cord-018042-qt7055fw	191	5	observed	observe	VBN
cord-018042-qt7055fw	191	6	-	-	:
cord-018042-qt7055fw	191	7	even	even	RB
cord-018042-qt7055fw	191	8	in	in	IN
cord-018042-qt7055fw	191	9	areas	area	NNS
cord-018042-qt7055fw	191	10	in	in	IN
cord-018042-qt7055fw	191	11	which	which	WDT
cord-018042-qt7055fw	191	12	the	the	DT
cord-018042-qt7055fw	191	13	BBB	BBB	NNP
cord-018042-qt7055fw	191	14	was	be	VBD
cord-018042-qt7055fw	191	15	disrupted	disrupt	VBN
cord-018042-qt7055fw	191	16	.	.	.
cord-018042-qt7055fw	192	1	The	the	DT
cord-018042-qt7055fw	192	2	lack	lack	NN
cord-018042-qt7055fw	192	3	of	of	IN
cord-018042-qt7055fw	192	4	lymphocyte	lymphocyte	NN
cord-018042-qt7055fw	192	5	infiltration	infiltration	NN
cord-018042-qt7055fw	192	6	is	be	VBZ
cord-018042-qt7055fw	192	7	a	a	DT
cord-018042-qt7055fw	192	8	notable	notable	JJ
cord-018042-qt7055fw	192	9	finding	finding	NN
cord-018042-qt7055fw	192	10	because	because	IN
cord-018042-qt7055fw	192	11	transgenic	transgenic	JJ
cord-018042-qt7055fw	192	12	expression	expression	NN
cord-018042-qt7055fw	192	13	of	of	IN
cord-018042-qt7055fw	192	14	CCL21	CCL21	NNP
cord-018042-qt7055fw	192	15	in	in	IN
cord-018042-qt7055fw	192	16	the	the	DT
cord-018042-qt7055fw	192	17	pancreas	pancreas	NN
cord-018042-qt7055fw	192	18	induced	induce	VBN
cord-018042-qt7055fw	192	19	lymphocyte	lymphocyte	NN
cord-018042-qt7055fw	192	20	influx	influx	NN
cord-018042-qt7055fw	192	21	and	and	CC
cord-018042-qt7055fw	192	22	led	lead	VBD
cord-018042-qt7055fw	192	23	to	to	IN
cord-018042-qt7055fw	192	24	the	the	DT
cord-018042-qt7055fw	192	25	formation	formation	NN
cord-018042-qt7055fw	192	26	of	of	IN
cord-018042-qt7055fw	192	27	lymph	lymph	NN
cord-018042-qt7055fw	192	28	node	node	NN
cord-018042-qt7055fw	192	29	like	like	IN
cord-018042-qt7055fw	192	30	structures	structure	NNS
cord-018042-qt7055fw	192	31	(	(	-LRB-
cord-018042-qt7055fw	192	32	Fan	Fan	NNP
cord-018042-qt7055fw	192	33	et	et	NNP
cord-018042-qt7055fw	192	34	al	al	NNP
cord-018042-qt7055fw	192	35	.	.	NNP
cord-018042-qt7055fw	192	36	,	,	,
cord-018042-qt7055fw	192	37	2000	2000	CD
cord-018042-qt7055fw	192	38	;	;	:
cord-018042-qt7055fw	192	39	Chen	Chen	NNP
cord-018042-qt7055fw	192	40	et	et	NNP
cord-018042-qt7055fw	192	41	al	al	NNP
cord-018042-qt7055fw	192	42	.	.	.
cord-018042-qt7055fw	193	1	,	,	,
cord-018042-qt7055fw	193	2	2002b	2002b	CD
cord-018042-qt7055fw	193	3	)	)	-RRB-
cord-018042-qt7055fw	193	4	.	.	.
cord-018042-qt7055fw	194	1	It	-PRON-	PRP
cord-018042-qt7055fw	194	2	would	would	MD
cord-018042-qt7055fw	194	3	thus	thus	RB
cord-018042-qt7055fw	194	4	appear	appear	VB
cord-018042-qt7055fw	194	5	that	that	IN
cord-018042-qt7055fw	194	6	tissue	tissue	NN
cord-018042-qt7055fw	194	7	-	-	HYPH
cord-018042-qt7055fw	194	8	specific	specific	JJ
cord-018042-qt7055fw	194	9	factors	factor	NNS
cord-018042-qt7055fw	194	10	that	that	WDT
cord-018042-qt7055fw	194	11	might	may	MD
cord-018042-qt7055fw	194	12	include	include	VB
cord-018042-qt7055fw	194	13	for	for	IN
cord-018042-qt7055fw	194	14	example	example	NN
cord-018042-qt7055fw	194	15	,	,	,
cord-018042-qt7055fw	194	16	specific	specific	JJ
cord-018042-qt7055fw	194	17	adhesion	adhesion	NN
cord-018042-qt7055fw	194	18	molecules	molecule	NNS
cord-018042-qt7055fw	194	19	and	and	CC
cord-018042-qt7055fw	194	20	other	other	JJ
cord-018042-qt7055fw	194	21	cofactors	cofactor	NNS
cord-018042-qt7055fw	194	22	,	,	,
cord-018042-qt7055fw	194	23	are	be	VBP
cord-018042-qt7055fw	194	24	required	require	VBN
cord-018042-qt7055fw	194	25	for	for	IN
cord-018042-qt7055fw	194	26	CCL21	CCL21	NNP
cord-018042-qt7055fw	194	27	to	to	TO
cord-018042-qt7055fw	194	28	induce	induce	VB
cord-018042-qt7055fw	194	29	lymphocyte	lymphocyte	NN
cord-018042-qt7055fw	194	30	recruitment	recruitment	NN
cord-018042-qt7055fw	194	31	.	.	.
cord-018042-qt7055fw	195	1	As	as	IN
cord-018042-qt7055fw	195	2	pointed	point	VBN
cord-018042-qt7055fw	195	3	out	out	RP
cord-018042-qt7055fw	195	4	by	by	IN
cord-018042-qt7055fw	195	5	the	the	DT
cord-018042-qt7055fw	195	6	Authors	author	NNS
cord-018042-qt7055fw	195	7	the	the	DT
cord-018042-qt7055fw	195	8	phenotypic	phenotypic	JJ
cord-018042-qt7055fw	195	9	differences	difference	NNS
cord-018042-qt7055fw	195	10	observed	observe	VBN
cord-018042-qt7055fw	195	11	between	between	IN
cord-018042-qt7055fw	195	12	MBP	MBP	NNP
cord-018042-qt7055fw	195	13	-	-	HYPH
cord-018042-qt7055fw	195	14	CCL21	CCL21	NNP
cord-018042-qt7055fw	195	15	and	and	CC
cord-018042-qt7055fw	195	16	MBP	MBP	NNP
cord-018042-qt7055fw	195	17	-	-	HYPH
cord-018042-qt7055fw	195	18	CCL19	CCL19	NNP
cord-018042-qt7055fw	195	19	transgenic	transgenic	JJ
cord-018042-qt7055fw	195	20	mice	mouse	NNS
cord-018042-qt7055fw	195	21	is	be	VBZ
cord-018042-qt7055fw	195	22	very	very	RB
cord-018042-qt7055fw	195	23	interesting	interesting	JJ
cord-018042-qt7055fw	195	24	given	give	VBN
cord-018042-qt7055fw	195	25	that	that	IN
cord-018042-qt7055fw	195	26	these	these	DT
cord-018042-qt7055fw	195	27	chemokines	chemokine	NNS
cord-018042-qt7055fw	195	28	are	be	VBP
cord-018042-qt7055fw	195	29	functionally	functionally	RB
cord-018042-qt7055fw	195	30	related	related	JJ
cord-018042-qt7055fw	195	31	and	and	CC
cord-018042-qt7055fw	195	32	bind	bind	VB
cord-018042-qt7055fw	195	33	to	to	IN
cord-018042-qt7055fw	195	34	the	the	DT
cord-018042-qt7055fw	195	35	same	same	JJ
cord-018042-qt7055fw	195	36	cell	cell	NN
cord-018042-qt7055fw	195	37	surface	surface	NN
cord-018042-qt7055fw	195	38	receptors	receptor	NNS
cord-018042-qt7055fw	195	39	,	,	,
cord-018042-qt7055fw	195	40	CCR7	CCR7	NNP
cord-018042-qt7055fw	195	41	and	and	CC
cord-018042-qt7055fw	195	42	CCR11	CCR11	NNP
cord-018042-qt7055fw	195	43	.	.	.
cord-018042-qt7055fw	196	1	However	however	RB
cord-018042-qt7055fw	196	2	,	,	,
cord-018042-qt7055fw	196	3	and	and	CC
cord-018042-qt7055fw	196	4	as	as	IN
cord-018042-qt7055fw	196	5	noted	note	VBN
cord-018042-qt7055fw	196	6	above	above	IN
cord-018042-qt7055fw	196	7	CCL21	CCL21	NNP
cord-018042-qt7055fw	196	8	but	but	CC
cord-018042-qt7055fw	196	9	not	not	RB
cord-018042-qt7055fw	196	10	CCL19	CCL19	NNP
cord-018042-qt7055fw	196	11	also	also	RB
cord-018042-qt7055fw	196	12	binds	bind	VBZ
cord-018042-qt7055fw	196	13	to	to	IN
cord-018042-qt7055fw	196	14	CXCR3	cxcr3	NN
cord-018042-qt7055fw	196	15	,	,	,
cord-018042-qt7055fw	196	16	which	which	WDT
cord-018042-qt7055fw	196	17	in	in	IN
cord-018042-qt7055fw	196	18	the	the	DT
cord-018042-qt7055fw	196	19	case	case	NN
cord-018042-qt7055fw	196	20	of	of	IN
cord-018042-qt7055fw	196	21	murine	murine	JJ
cord-018042-qt7055fw	196	22	microglia	microglia	NN
cord-018042-qt7055fw	196	23	produces	produce	VBZ
cord-018042-qt7055fw	196	24	functional	functional	JJ
cord-018042-qt7055fw	196	25	alterations	alteration	NNS
cord-018042-qt7055fw	196	26	in	in	IN
cord-018042-qt7055fw	196	27	these	these	DT
cord-018042-qt7055fw	196	28	cells	cell	NNS
cord-018042-qt7055fw	196	29	(	(	-LRB-
cord-018042-qt7055fw	196	30	Rappert	Rappert	NNP
cord-018042-qt7055fw	196	31	et	et	NNP
cord-018042-qt7055fw	196	32	al	al	NNP
cord-018042-qt7055fw	196	33	.	.	NNP
cord-018042-qt7055fw	196	34	,	,	,
cord-018042-qt7055fw	196	35	2002	2002	CD
cord-018042-qt7055fw	196	36	)	)	-RRB-
cord-018042-qt7055fw	196	37	.	.	.
cord-018042-qt7055fw	197	1	Interestingly	interestingly	RB
cord-018042-qt7055fw	197	2	,	,	,
cord-018042-qt7055fw	197	3	the	the	DT
cord-018042-qt7055fw	197	4	same	same	JJ
cord-018042-qt7055fw	197	5	workers	worker	NNS
cord-018042-qt7055fw	197	6	have	have	VBP
cord-018042-qt7055fw	197	7	reported	report	VBN
cord-018042-qt7055fw	197	8	that	that	IN
cord-018042-qt7055fw	197	9	neurons	neuron	NNS
cord-018042-qt7055fw	197	10	in	in	IN
cord-018042-qt7055fw	197	11	the	the	DT
cord-018042-qt7055fw	197	12	ischemic	ischemic	JJ
cord-018042-qt7055fw	197	13	brain	brain	NN
cord-018042-qt7055fw	197	14	produce	produce	VBP
cord-018042-qt7055fw	197	15	CCL21	CCL21	NNP
cord-018042-qt7055fw	197	16	(	(	-LRB-
cord-018042-qt7055fw	197	17	Biber	Biber	NNP
cord-018042-qt7055fw	197	18	et	et	NNP
cord-018042-qt7055fw	197	19	al	al	NNP
cord-018042-qt7055fw	197	20	.	.	NNP
cord-018042-qt7055fw	197	21	,	,	,
cord-018042-qt7055fw	197	22	2001	2001	CD
cord-018042-qt7055fw	197	23	)	)	-RRB-
cord-018042-qt7055fw	197	24	.	.	.
cord-018042-qt7055fw	198	1	These	these	DT
cord-018042-qt7055fw	198	2	observations	observation	NNS
cord-018042-qt7055fw	198	3	have	have	VBP
cord-018042-qt7055fw	198	4	led	lead	VBN
cord-018042-qt7055fw	198	5	to	to	IN
cord-018042-qt7055fw	198	6	the	the	DT
cord-018042-qt7055fw	198	7	suggestion	suggestion	NN
cord-018042-qt7055fw	198	8	that	that	IN
cord-018042-qt7055fw	198	9	CCL21	CCL21	NNP
cord-018042-qt7055fw	198	10	and	and	CC
cord-018042-qt7055fw	198	11	CXCR3	CXCR3	NNP
cord-018042-qt7055fw	198	12	may	may	MD
cord-018042-qt7055fw	198	13	mediate	mediate	VB
cord-018042-qt7055fw	198	14	neuron	neuron	NN
cord-018042-qt7055fw	198	15	-	-	HYPH
cord-018042-qt7055fw	198	16	glia	glia	NN
cord-018042-qt7055fw	198	17	interactions	interaction	NNS
cord-018042-qt7055fw	198	18	during	during	IN
cord-018042-qt7055fw	198	19	disease	disease	NN
cord-018042-qt7055fw	198	20	conditions	condition	NNS
cord-018042-qt7055fw	198	21	.	.	.
cord-018042-qt7055fw	199	1	It	-PRON-	PRP
cord-018042-qt7055fw	199	2	is	be	VBZ
cord-018042-qt7055fw	199	3	speculated	speculate	VBN
cord-018042-qt7055fw	199	4	that	that	IN
cord-018042-qt7055fw	199	5	CCL21	CCL21	NNP
cord-018042-qt7055fw	199	6	derived	derive	VBN
cord-018042-qt7055fw	199	7	from	from	IN
cord-018042-qt7055fw	199	8	transgenic	transgenic	JJ
cord-018042-qt7055fw	199	9	oligodendrocytes	oligodendrocyte	NNS
cord-018042-qt7055fw	199	10	in	in	IN
cord-018042-qt7055fw	199	11	the	the	DT
cord-018042-qt7055fw	199	12	brain	brain	NN
cord-018042-qt7055fw	199	13	of	of	IN
cord-018042-qt7055fw	199	14	the	the	DT
cord-018042-qt7055fw	199	15	MBP	MBP	NNP
cord-018042-qt7055fw	199	16	-	-	HYPH
cord-018042-qt7055fw	199	17	CCL21	CCL21	NNP
cord-018042-qt7055fw	199	18	mice	mouse	NNS
cord-018042-qt7055fw	199	19	may	may	MD
cord-018042-qt7055fw	199	20	have	have	VB
cord-018042-qt7055fw	199	21	interacted	interact	VBN
cord-018042-qt7055fw	199	22	with	with	IN
cord-018042-qt7055fw	199	23	CXCR3	CXCR3	NNP
cord-018042-qt7055fw	199	24	on	on	IN
cord-018042-qt7055fw	199	25	microglia	microglia	NN
cord-018042-qt7055fw	199	26	inducing	induce	VBG
cord-018042-qt7055fw	199	27	an	an	DT
cord-018042-qt7055fw	199	28	inflammatory	inflammatory	JJ
cord-018042-qt7055fw	199	29	response	response	NN
cord-018042-qt7055fw	199	30	that	that	WDT
cord-018042-qt7055fw	199	31	led	lead	VBD
cord-018042-qt7055fw	199	32	to	to	IN
cord-018042-qt7055fw	199	33	the	the	DT
cord-018042-qt7055fw	199	34	influx	influx	NN
cord-018042-qt7055fw	199	35	of	of	IN
cord-018042-qt7055fw	199	36	inflammatory	inflammatory	JJ
cord-018042-qt7055fw	199	37	cells	cell	NNS
cord-018042-qt7055fw	199	38	into	into	IN
cord-018042-qt7055fw	199	39	the	the	DT
cord-018042-qt7055fw	199	40	CNS	CNS	NNP
cord-018042-qt7055fw	199	41	.	.	.
cord-018042-qt7055fw	200	1	While	while	IN
cord-018042-qt7055fw	200	2	further	further	JJ
cord-018042-qt7055fw	200	3	studies	study	NNS
cord-018042-qt7055fw	200	4	,	,	,
cord-018042-qt7055fw	200	5	such	such	JJ
cord-018042-qt7055fw	200	6	as	as	IN
cord-018042-qt7055fw	200	7	crossing	cross	VBG
cord-018042-qt7055fw	200	8	the	the	DT
cord-018042-qt7055fw	200	9	MBP	MBP	NNP
cord-018042-qt7055fw	200	10	-	-	HYPH
cord-018042-qt7055fw	200	11	CCL21	CCL21	NNP
cord-018042-qt7055fw	200	12	transgenic	transgenic	JJ
cord-018042-qt7055fw	200	13	mice	mouse	NNS
cord-018042-qt7055fw	200	14	with	with	IN
cord-018042-qt7055fw	200	15	CXCR3	cxcr3	NN
cord-018042-qt7055fw	200	16	deficient	deficient	JJ
cord-018042-qt7055fw	200	17	animals	animal	NNS
cord-018042-qt7055fw	200	18	,	,	,
cord-018042-qt7055fw	200	19	would	would	MD
cord-018042-qt7055fw	200	20	help	help	VB
cord-018042-qt7055fw	200	21	to	to	TO
cord-018042-qt7055fw	200	22	clarify	clarify	VB
cord-018042-qt7055fw	200	23	this	this	DT
cord-018042-qt7055fw	200	24	mechanism	mechanism	NN
cord-018042-qt7055fw	200	25	,	,	,
cord-018042-qt7055fw	200	26	as	as	IN
cord-018042-qt7055fw	200	27	noted	note	VBN
cord-018042-qt7055fw	200	28	in	in	IN
cord-018042-qt7055fw	200	29	the	the	DT
cord-018042-qt7055fw	200	30	preceding	precede	VBG
cord-018042-qt7055fw	200	31	discussion	discussion	NN
cord-018042-qt7055fw	200	32	,	,	,
cord-018042-qt7055fw	200	33	transgenic	transgenic	JJ
cord-018042-qt7055fw	200	34	mice	mouse	NNS
cord-018042-qt7055fw	200	35	with	with	IN
cord-018042-qt7055fw	200	36	astrocyte	astrocyte	RB
cord-018042-qt7055fw	200	37	-	-	HYPH
cord-018042-qt7055fw	200	38	targeted	target	VBN
cord-018042-qt7055fw	200	39	production	production	NN
cord-018042-qt7055fw	200	40	of	of	IN
cord-018042-qt7055fw	200	41	the	the	DT
cord-018042-qt7055fw	200	42	primary	primary	JJ
cord-018042-qt7055fw	200	43	CXCR3	cxcr3	NN
cord-018042-qt7055fw	200	44	ligand	ligand	NN
cord-018042-qt7055fw	201	1	CXCL10	CXCL10	NNS
cord-018042-qt7055fw	201	2	do	do	VB
cord-018042-qt7055fw	201	3	not	not	RB
cord-018042-qt7055fw	201	4	share	share	VB
cord-018042-qt7055fw	201	5	the	the	DT
cord-018042-qt7055fw	201	6	severe	severe	JJ
cord-018042-qt7055fw	201	7	neurological	neurological	JJ
cord-018042-qt7055fw	201	8	phenotype	phenotype	NN
cord-018042-qt7055fw	201	9	of	of	IN
cord-018042-qt7055fw	201	10	the	the	DT
cord-018042-qt7055fw	201	11	MBP	MBP	NNP
cord-018042-qt7055fw	201	12	-	-	HYPH
cord-018042-qt7055fw	201	13	CCL2	CCL2	NNP
cord-018042-qt7055fw	201	14	mice	mouse	NNS
cord-018042-qt7055fw	201	15	.	.	.
cord-018042-qt7055fw	202	1	An	an	DT
cord-018042-qt7055fw	202	2	important	important	JJ
cord-018042-qt7055fw	202	3	constraint	constraint	NN
cord-018042-qt7055fw	202	4	with	with	IN
cord-018042-qt7055fw	202	5	the	the	DT
cord-018042-qt7055fw	202	6	transgenic	transgenic	JJ
cord-018042-qt7055fw	202	7	approach	approach	NN
cord-018042-qt7055fw	202	8	that	that	WDT
cord-018042-qt7055fw	202	9	needs	need	VBZ
cord-018042-qt7055fw	202	10	to	to	TO
cord-018042-qt7055fw	202	11	be	be	VB
cord-018042-qt7055fw	202	12	considered	consider	VBN
cord-018042-qt7055fw	202	13	relates	relate	NNS
cord-018042-qt7055fw	202	14	to	to	IN
cord-018042-qt7055fw	202	15	the	the	DT
cord-018042-qt7055fw	202	16	spatial	spatial	JJ
cord-018042-qt7055fw	202	17	and	and	CC
cord-018042-qt7055fw	202	18	temporal	temporal	JJ
cord-018042-qt7055fw	202	19	control	control	NN
cord-018042-qt7055fw	202	20	of	of	IN
cord-018042-qt7055fw	202	21	transgene	transgene	JJ
cord-018042-qt7055fw	202	22	expression	expression	NN
cord-018042-qt7055fw	202	23	.	.	.
cord-018042-qt7055fw	203	1	The	the	DT
cord-018042-qt7055fw	203	2	production	production	NN
cord-018042-qt7055fw	203	3	of	of	IN
cord-018042-qt7055fw	203	4	chemokines	chemokine	NNS
cord-018042-qt7055fw	203	5	in	in	IN
cord-018042-qt7055fw	203	6	pathologic	pathologic	JJ
cord-018042-qt7055fw	203	7	states	state	NNS
cord-018042-qt7055fw	203	8	such	such	JJ
cord-018042-qt7055fw	203	9	as	as	IN
cord-018042-qt7055fw	203	10	in	in	IN
cord-018042-qt7055fw	203	11	EAE	EAE	NNP
cord-018042-qt7055fw	203	12	is	be	VBZ
cord-018042-qt7055fw	203	13	regulated	regulate	VBN
cord-018042-qt7055fw	203	14	in	in	IN
cord-018042-qt7055fw	203	15	a	a	DT
cord-018042-qt7055fw	203	16	temporal	temporal	JJ
cord-018042-qt7055fw	203	17	fashion	fashion	NN
cord-018042-qt7055fw	203	18	that	that	WDT
cord-018042-qt7055fw	203	19	precedes	precede	VBZ
cord-018042-qt7055fw	203	20	and	and	CC
cord-018042-qt7055fw	203	21	then	then	RB
cord-018042-qt7055fw	203	22	overlaps	overlap	VBZ
cord-018042-qt7055fw	203	23	with	with	IN
cord-018042-qt7055fw	203	24	the	the	DT
cord-018042-qt7055fw	203	25	severity	severity	NN
cord-018042-qt7055fw	203	26	of	of	IN
cord-018042-qt7055fw	203	27	the	the	DT
cord-018042-qt7055fw	203	28	disease	disease	NN
cord-018042-qt7055fw	203	29	process	process	NN
cord-018042-qt7055fw	203	30	.	.	.
cord-018042-qt7055fw	204	1	Moreover	moreover	RB
cord-018042-qt7055fw	204	2	,	,	,
cord-018042-qt7055fw	204	3	the	the	DT
cord-018042-qt7055fw	204	4	spatial	spatial	JJ
cord-018042-qt7055fw	204	5	pattern	pattern	NN
cord-018042-qt7055fw	204	6	of	of	IN
cord-018042-qt7055fw	204	7	expression	expression	NN
cord-018042-qt7055fw	204	8	of	of	IN
cord-018042-qt7055fw	204	9	chemokines	chemokine	NNS
cord-018042-qt7055fw	204	10	such	such	JJ
cord-018042-qt7055fw	204	11	as	as	IN
cord-018042-qt7055fw	204	12	CXCL10	CXCL10	NNP
cord-018042-qt7055fw	204	13	is	be	VBZ
cord-018042-qt7055fw	204	14	focally	focally	RB
cord-018042-qt7055fw	204	15	restricted	restricted	JJ
cord-018042-qt7055fw	204	16	to	to	IN
cord-018042-qt7055fw	204	17	the	the	DT
cord-018042-qt7055fw	204	18	immunoinflammatory	immunoinflammatory	NNP
cord-018042-qt7055fw	204	19	lesions	lesion	NNS
cord-018042-qt7055fw	204	20	.	.	.
cord-018042-qt7055fw	205	1	The	the	DT
cord-018042-qt7055fw	205	2	production	production	NN
cord-018042-qt7055fw	205	3	of	of	IN
cord-018042-qt7055fw	205	4	chemokines	chemokine	NNS
cord-018042-qt7055fw	205	5	achieved	achieve	VBN
cord-018042-qt7055fw	205	6	in	in	IN
cord-018042-qt7055fw	205	7	pathologic	pathologic	JJ
cord-018042-qt7055fw	205	8	states	state	NNS
cord-018042-qt7055fw	205	9	therefore	therefore	RB
cord-018042-qt7055fw	205	10	would	would	MD
cord-018042-qt7055fw	205	11	favor	favor	VB
cord-018042-qt7055fw	205	12	the	the	DT
cord-018042-qt7055fw	205	13	establishment	establishment	NN
cord-018042-qt7055fw	205	14	of	of	IN
cord-018042-qt7055fw	205	15	highly	highly	RB
cord-018042-qt7055fw	205	16	localized	localize	VBN
cord-018042-qt7055fw	205	17	chemoattractant	chemoattractant	NN
cord-018042-qt7055fw	205	18	gradients	gradient	NNS
cord-018042-qt7055fw	205	19	that	that	WDT
cord-018042-qt7055fw	205	20	then	then	RB
cord-018042-qt7055fw	205	21	guide	guide	VB
cord-018042-qt7055fw	205	22	the	the	DT
cord-018042-qt7055fw	205	23	trafficking	trafficking	NN
cord-018042-qt7055fw	205	24	of	of	IN
cord-018042-qt7055fw	205	25	leukocytes	leukocyte	NNS
cord-018042-qt7055fw	205	26	.	.	.
cord-018042-qt7055fw	206	1	In	in	IN
cord-018042-qt7055fw	206	2	contrast	contrast	NN
cord-018042-qt7055fw	206	3	,	,	,
cord-018042-qt7055fw	206	4	in	in	IN
cord-018042-qt7055fw	206	5	the	the	DT
cord-018042-qt7055fw	206	6	transgenic	transgenic	JJ
cord-018042-qt7055fw	206	7	model	model	NN
cord-018042-qt7055fw	206	8	the	the	DT
cord-018042-qt7055fw	206	9	chemokine	chemokine	NN
cord-018042-qt7055fw	206	10	is	be	VBZ
cord-018042-qt7055fw	206	11	produced	produce	VBN
cord-018042-qt7055fw	206	12	more	more	RBR
cord-018042-qt7055fw	206	13	chronically	chronically	RB
cord-018042-qt7055fw	206	14	and	and	CC
cord-018042-qt7055fw	206	15	more	more	RBR
cord-018042-qt7055fw	206	16	diffusely	diffusely	RB
cord-018042-qt7055fw	206	17	throughout	throughout	IN
cord-018042-qt7055fw	206	18	the	the	DT
cord-018042-qt7055fw	206	19	CNS	CNS	NNP
cord-018042-qt7055fw	206	20	.	.	.
cord-018042-qt7055fw	207	1	In	in	IN
cord-018042-qt7055fw	207	2	addition	addition	NN
cord-018042-qt7055fw	207	3	to	to	IN
cord-018042-qt7055fw	207	4	the	the	DT
cord-018042-qt7055fw	207	5	potential	potential	NN
cord-018042-qt7055fw	207	6	for	for	IN
cord-018042-qt7055fw	207	7	receptor	receptor	NN
cord-018042-qt7055fw	207	8	down	down	IN
cord-018042-qt7055fw	207	9	-	-	HYPH
cord-018042-qt7055fw	207	10	regulation	regulation	NN
cord-018042-qt7055fw	207	11	and	and	CC
cord-018042-qt7055fw	207	12	desensitization	desensitization	NN
cord-018042-qt7055fw	207	13	of	of	IN
cord-018042-qt7055fw	207	14	the	the	DT
cord-018042-qt7055fw	207	15	ligand	ligand	NN
cord-018042-qt7055fw	207	16	response	response	NN
cord-018042-qt7055fw	207	17	,	,	,
cord-018042-qt7055fw	207	18	it	-PRON-	PRP
cord-018042-qt7055fw	207	19	is	be	VBZ
cord-018042-qt7055fw	207	20	likely	likely	JJ
cord-018042-qt7055fw	207	21	that	that	IN
cord-018042-qt7055fw	207	22	any	any	DT
cord-018042-qt7055fw	207	23	chemoattractant	chemoattractant	JJ
cord-018042-qt7055fw	207	24	gradient	gradient	NN
cord-018042-qt7055fw	207	25	in	in	IN
cord-018042-qt7055fw	207	26	this	this	DT
cord-018042-qt7055fw	207	27	milieu	milieu	NN
cord-018042-qt7055fw	207	28	would	would	MD
cord-018042-qt7055fw	207	29	be	be	VB
cord-018042-qt7055fw	207	30	much	much	RB
cord-018042-qt7055fw	207	31	weaker	weak	JJR
cord-018042-qt7055fw	207	32	in	in	IN
cord-018042-qt7055fw	207	33	strength	strength	NN
cord-018042-qt7055fw	207	34	and	and	CC
cord-018042-qt7055fw	207	35	more	more	RBR
cord-018042-qt7055fw	207	36	widely	widely	RB
cord-018042-qt7055fw	207	37	distributed	distribute	VBN
cord-018042-qt7055fw	207	38	.	.	.
cord-018042-qt7055fw	208	1	Technically	technically	RB
cord-018042-qt7055fw	208	2	achieving	achieve	VBG
cord-018042-qt7055fw	208	3	more	more	RBR
cord-018042-qt7055fw	208	4	acute	acute	JJ
cord-018042-qt7055fw	208	5	and	and	CC
cord-018042-qt7055fw	208	6	focal	focal	JJ
cord-018042-qt7055fw	208	7	expression	expression	NN
cord-018042-qt7055fw	208	8	of	of	IN
cord-018042-qt7055fw	208	9	the	the	DT
cord-018042-qt7055fw	208	10	chemokine	chemokine	NN
cord-018042-qt7055fw	208	11	to	to	TO
cord-018042-qt7055fw	208	12	better	well	RBR
cord-018042-qt7055fw	208	13	replicate	replicate	VB
cord-018042-qt7055fw	208	14	pathologic	pathologic	JJ
cord-018042-qt7055fw	208	15	states	state	NNS
cord-018042-qt7055fw	208	16	in	in	IN
cord-018042-qt7055fw	208	17	the	the	DT
cord-018042-qt7055fw	208	18	adult	adult	NN
cord-018042-qt7055fw	208	19	brain	brain	NN
cord-018042-qt7055fw	208	20	using	use	VBG
cord-018042-qt7055fw	208	21	transgenic	transgenic	JJ
cord-018042-qt7055fw	208	22	modeling	modeling	NN
cord-018042-qt7055fw	208	23	is	be	VBZ
cord-018042-qt7055fw	208	24	clearly	clearly	RB
cord-018042-qt7055fw	208	25	desirable	desirable	JJ
cord-018042-qt7055fw	208	26	but	but	CC
cord-018042-qt7055fw	208	27	difficult	difficult	JJ
cord-018042-qt7055fw	208	28	to	to	TO
cord-018042-qt7055fw	208	29	achieve	achieve	VB
cord-018042-qt7055fw	208	30	at	at	IN
cord-018042-qt7055fw	208	31	this	this	DT
cord-018042-qt7055fw	208	32	time	time	NN
cord-018042-qt7055fw	208	33	.	.	.
cord-018042-qt7055fw	209	1	Although	although	IN
cord-018042-qt7055fw	209	2	constructs	construct	NNS
cord-018042-qt7055fw	209	3	have	have	VBP
cord-018042-qt7055fw	209	4	been	be	VBN
cord-018042-qt7055fw	209	5	engineered	engineer	VBN
cord-018042-qt7055fw	209	6	that	that	WDT
cord-018042-qt7055fw	209	7	permit	permit	VBP
cord-018042-qt7055fw	209	8	the	the	DT
cord-018042-qt7055fw	209	9	temporal	temporal	JJ
cord-018042-qt7055fw	209	10	control	control	NN
cord-018042-qt7055fw	209	11	of	of	IN
cord-018042-qt7055fw	209	12	transgene	transgene	JJ
cord-018042-qt7055fw	209	13	expression	expression	NN
cord-018042-qt7055fw	209	14	in	in	IN
cord-018042-qt7055fw	209	15	the	the	DT
cord-018042-qt7055fw	209	16	CNS	CNS	NNP
cord-018042-qt7055fw	209	17	,	,	,
cord-018042-qt7055fw	209	18	more	more	RBR
cord-018042-qt7055fw	209	19	precise	precise	JJ
cord-018042-qt7055fw	209	20	spatial	spatial	JJ
cord-018042-qt7055fw	209	21	targeting	targeting	NN
cord-018042-qt7055fw	209	22	that	that	WDT
cord-018042-qt7055fw	209	23	would	would	MD
cord-018042-qt7055fw	209	24	allow	allow	VB
cord-018042-qt7055fw	209	25	for	for	IN
cord-018042-qt7055fw	209	26	highly	highly	RB
cord-018042-qt7055fw	209	27	localized	localize	VBN
cord-018042-qt7055fw	209	28	production	production	NN
cord-018042-qt7055fw	209	29	of	of	IN
cord-018042-qt7055fw	209	30	the	the	DT
cord-018042-qt7055fw	209	31	chemokine	chemokine	NN
cord-018042-qt7055fw	209	32	in	in	IN
cord-018042-qt7055fw	209	33	neural	neural	JJ
cord-018042-qt7055fw	209	34	cells	cell	NNS
cord-018042-qt7055fw	209	35	such	such	JJ
cord-018042-qt7055fw	209	36	as	as	IN
cord-018042-qt7055fw	209	37	astrocytes	astrocyte	NNS
cord-018042-qt7055fw	209	38	is	be	VBZ
cord-018042-qt7055fw	209	39	not	not	RB
cord-018042-qt7055fw	209	40	yet	yet	RB
cord-018042-qt7055fw	209	41	possible	possible	JJ
cord-018042-qt7055fw	209	42	.	.	.
cord-018042-qt7055fw	210	1	Despite	despite	IN
cord-018042-qt7055fw	210	2	the	the	DT
cord-018042-qt7055fw	210	3	drawbacks	drawback	NNS
cord-018042-qt7055fw	210	4	noted	note	VBN
cord-018042-qt7055fw	210	5	in	in	IN
cord-018042-qt7055fw	210	6	the	the	DT
cord-018042-qt7055fw	210	7	preceding	precede	VBG
cord-018042-qt7055fw	210	8	discussion	discussion	NN
cord-018042-qt7055fw	210	9	,	,	,
cord-018042-qt7055fw	210	10	it	-PRON-	PRP
cord-018042-qt7055fw	210	11	is	be	VBZ
cord-018042-qt7055fw	210	12	clear	clear	JJ
cord-018042-qt7055fw	210	13	that	that	IN
cord-018042-qt7055fw	210	14	development	development	NN
cord-018042-qt7055fw	210	15	of	of	IN
cord-018042-qt7055fw	210	16	molecular	molecular	JJ
cord-018042-qt7055fw	210	17	genetic	genetic	JJ
cord-018042-qt7055fw	210	18	methods	method	NNS
cord-018042-qt7055fw	210	19	that	that	WDT
cord-018042-qt7055fw	210	20	allow	allow	VBP
cord-018042-qt7055fw	210	21	for	for	IN
cord-018042-qt7055fw	210	22	the	the	DT
cord-018042-qt7055fw	210	23	targeted	target	VBN
cord-018042-qt7055fw	210	24	manipulation	manipulation	NN
cord-018042-qt7055fw	210	25	of	of	IN
cord-018042-qt7055fw	210	26	gene	gene	NN
cord-018042-qt7055fw	210	27	expression	expression	NN
cord-018042-qt7055fw	210	28	in	in	IN
cord-018042-qt7055fw	210	29	an	an	DT
cord-018042-qt7055fw	210	30	intact	intact	JJ
cord-018042-qt7055fw	210	31	organism	organism	NN
cord-018042-qt7055fw	210	32	has	have	VBZ
cord-018042-qt7055fw	210	33	been	be	VBN
cord-018042-qt7055fw	210	34	important	important	JJ
cord-018042-qt7055fw	210	35	in	in	IN
cord-018042-qt7055fw	210	36	contributing	contribute	VBG
cord-018042-qt7055fw	210	37	to	to	IN
cord-018042-qt7055fw	210	38	our	-PRON-	PRP$
cord-018042-qt7055fw	210	39	understanding	understanding	NN
cord-018042-qt7055fw	210	40	of	of	IN
cord-018042-qt7055fw	210	41	the	the	DT
cord-018042-qt7055fw	210	42	actions	action	NNS
cord-018042-qt7055fw	210	43	of	of	IN
cord-018042-qt7055fw	210	44	chemokines	chemokine	NNS
cord-018042-qt7055fw	210	45	in	in	IN
cord-018042-qt7055fw	210	46	the	the	DT
cord-018042-qt7055fw	210	47	CNS	CNS	NNP
cord-018042-qt7055fw	210	48	in	in	IN
cord-018042-qt7055fw	210	49	physiologic	physiologic	JJ
cord-018042-qt7055fw	210	50	and	and	CC
cord-018042-qt7055fw	210	51	pathologic	pathologic	JJ
cord-018042-qt7055fw	210	52	states	state	NNS
cord-018042-qt7055fw	210	53	(	(	-LRB-
cord-018042-qt7055fw	210	54	see	see	VB
cord-018042-qt7055fw	210	55	Table	Table	NNP
cord-018042-qt7055fw	210	56	1	1	CD
cord-018042-qt7055fw	210	57	)	)	-RRB-
cord-018042-qt7055fw	210	58	.	.	.
cord-018042-qt7055fw	211	1	Promoter	promoter	NN
cord-018042-qt7055fw	211	2	-	-	HYPH
cord-018042-qt7055fw	211	3	driven	drive	VBN
cord-018042-qt7055fw	211	4	expression	expression	NN
cord-018042-qt7055fw	211	5	of	of	IN
cord-018042-qt7055fw	211	6	different	different	JJ
cord-018042-qt7055fw	211	7	biologically	biologically	RB
cord-018042-qt7055fw	211	8	relevant	relevant	JJ
cord-018042-qt7055fw	211	9	chemokines	chemokine	NNS
cord-018042-qt7055fw	211	10	in	in	IN
cord-018042-qt7055fw	211	11	the	the	DT
cord-018042-qt7055fw	211	12	CNS	CNS	NNP
cord-018042-qt7055fw	211	13	of	of	IN
cord-018042-qt7055fw	211	14	transgenic	transgenic	JJ
cord-018042-qt7055fw	211	15	mice	mouse	NNS
cord-018042-qt7055fw	211	16	highlight	highlight	VBP
cord-018042-qt7055fw	211	17	the	the	DT
cord-018042-qt7055fw	211	18	ability	ability	NN
cord-018042-qt7055fw	211	19	of	of	IN
cord-018042-qt7055fw	211	20	some	some	DT
cord-018042-qt7055fw	211	21	but	but	CC
cord-018042-qt7055fw	211	22	not	not	RB
cord-018042-qt7055fw	211	23	all	all	DT
cord-018042-qt7055fw	211	24	of	of	IN
cord-018042-qt7055fw	211	25	these	these	DT
cord-018042-qt7055fw	211	26	molecules	molecule	NNS
cord-018042-qt7055fw	211	27	to	to	TO
cord-018042-qt7055fw	211	28	stimulate	stimulate	VB
cord-018042-qt7055fw	211	29	the	the	DT
cord-018042-qt7055fw	211	30	recruitment	recruitment	NN
cord-018042-qt7055fw	211	31	but	but	CC
cord-018042-qt7055fw	211	32	commonly	commonly	RB
cord-018042-qt7055fw	211	33	not	not	RB
cord-018042-qt7055fw	211	34	the	the	DT
cord-018042-qt7055fw	211	35	functional	functional	JJ
cord-018042-qt7055fw	211	36	activation	activation	NN
cord-018042-qt7055fw	211	37	of	of	IN
cord-018042-qt7055fw	211	38	specific	specific	JJ
cord-018042-qt7055fw	211	39	subsets	subset	NNS
cord-018042-qt7055fw	211	40	of	of	IN
cord-018042-qt7055fw	211	41	leukocytes	leukocyte	NNS
cord-018042-qt7055fw	211	42	to	to	IN
cord-018042-qt7055fw	211	43	the	the	DT
cord-018042-qt7055fw	211	44	CNS	CNS	NNP
cord-018042-qt7055fw	211	45	.	.	.
cord-018042-qt7055fw	212	1	With	with	IN
cord-018042-qt7055fw	212	2	certain	certain	JJ
cord-018042-qt7055fw	212	3	chemokines	chemokine	NNS
cord-018042-qt7055fw	212	4	such	such	JJ
cord-018042-qt7055fw	212	5	as	as	IN
cord-018042-qt7055fw	212	6	CXCL10	CXCL10	NNP
cord-018042-qt7055fw	212	7	and	and	CC
cord-018042-qt7055fw	212	8	CCL21	CCL21	NNP
cord-018042-qt7055fw	212	9	,	,	,
cord-018042-qt7055fw	212	10	their	-PRON-	PRP$
cord-018042-qt7055fw	212	11	transgenic	transgenic	JJ
cord-018042-qt7055fw	212	12	production	production	NN
cord-018042-qt7055fw	212	13	in	in	IN
cord-018042-qt7055fw	212	14	the	the	DT
cord-018042-qt7055fw	212	15	CNS	CNS	NNP
cord-018042-qt7055fw	212	16	led	lead	VBD
cord-018042-qt7055fw	212	17	to	to	IN
cord-018042-qt7055fw	212	18	the	the	DT
cord-018042-qt7055fw	212	19	accumulation	accumulation	NN
cord-018042-qt7055fw	212	20	of	of	IN
cord-018042-qt7055fw	212	21	unexpected	unexpected	JJ
cord-018042-qt7055fw	212	22	leukocyte	leukocyte	NN
cord-018042-qt7055fw	212	23	phenotypes	phenotype	NNS
cord-018042-qt7055fw	212	24	that	that	WDT
cord-018042-qt7055fw	212	25	could	could	MD
cord-018042-qt7055fw	212	26	not	not	RB
cord-018042-qt7055fw	212	27	have	have	VB
cord-018042-qt7055fw	212	28	been	be	VBN
cord-018042-qt7055fw	212	29	predicted	predict	VBN
cord-018042-qt7055fw	212	30	based	base	VBN
cord-018042-qt7055fw	212	31	on	on	IN
cord-018042-qt7055fw	212	32	either	either	DT
cord-018042-qt7055fw	212	33	in	in	IN
cord-018042-qt7055fw	212	34	vitro	vitro	FW
cord-018042-qt7055fw	212	35	chemotaxis	chemotaxis	NN
cord-018042-qt7055fw	212	36	assays	assay	NNS
cord-018042-qt7055fw	212	37	or	or	CC
cord-018042-qt7055fw	212	38	the	the	DT
cord-018042-qt7055fw	212	39	known	know	VBN
cord-018042-qt7055fw	212	40	cellular	cellular	JJ
cord-018042-qt7055fw	212	41	distribution	distribution	NN
cord-018042-qt7055fw	212	42	of	of	IN
cord-018042-qt7055fw	212	43	the	the	DT
cord-018042-qt7055fw	212	44	receptor	receptor	NN
cord-018042-qt7055fw	212	45	.	.	.
cord-018042-qt7055fw	213	1	This	this	DT
cord-018042-qt7055fw	213	2	to	to	IN
cord-018042-qt7055fw	213	3	some	some	DT
cord-018042-qt7055fw	213	4	extent	extent	NN
cord-018042-qt7055fw	213	5	reflects	reflect	VBZ
cord-018042-qt7055fw	213	6	the	the	DT
cord-018042-qt7055fw	213	7	complexity	complexity	NN
cord-018042-qt7055fw	213	8	of	of	IN
cord-018042-qt7055fw	213	9	the	the	DT
cord-018042-qt7055fw	213	10	actions	action	NNS
cord-018042-qt7055fw	213	11	and	and	CC
cord-018042-qt7055fw	213	12	interactions	interaction	NNS
cord-018042-qt7055fw	213	13	between	between	IN
cord-018042-qt7055fw	213	14	chemokines	chemokine	NNS
cord-018042-qt7055fw	213	15	and	and	CC
cord-018042-qt7055fw	213	16	their	-PRON-	PRP$
cord-018042-qt7055fw	213	17	receptors	receptor	NNS
cord-018042-qt7055fw	213	18	many	many	JJ
cord-018042-qt7055fw	213	19	of	of	IN
cord-018042-qt7055fw	213	20	which	which	WDT
cord-018042-qt7055fw	213	21	we	-PRON-	PRP
cord-018042-qt7055fw	213	22	know	know	VBP
cord-018042-qt7055fw	213	23	to	to	TO
cord-018042-qt7055fw	213	24	be	be	VB
cord-018042-qt7055fw	213	25	promiscuous	promiscuous	JJ
cord-018042-qt7055fw	213	26	for	for	IN
cord-018042-qt7055fw	213	27	the	the	DT
cord-018042-qt7055fw	213	28	ligands	ligand	NNS
cord-018042-qt7055fw	213	29	they	-PRON-	PRP
cord-018042-qt7055fw	213	30	bind	bind	VBP
cord-018042-qt7055fw	213	31	.	.	.
cord-018042-qt7055fw	214	1	Moreover	moreover	RB
cord-018042-qt7055fw	214	2	,	,	,
cord-018042-qt7055fw	214	3	differences	difference	NNS
cord-018042-qt7055fw	214	4	in	in	IN
cord-018042-qt7055fw	214	5	the	the	DT
cord-018042-qt7055fw	214	6	immunophenotype	immunophenotype	NN
cord-018042-qt7055fw	214	7	of	of	IN
cord-018042-qt7055fw	214	8	leukocytes	leukocyte	NNS
cord-018042-qt7055fw	214	9	recruited	recruit	VBN
cord-018042-qt7055fw	214	10	to	to	IN
cord-018042-qt7055fw	214	11	the	the	DT
cord-018042-qt7055fw	214	12	CNS	CNS	NNP
cord-018042-qt7055fw	214	13	versus	versus	IN
cord-018042-qt7055fw	214	14	peripheral	peripheral	JJ
cord-018042-qt7055fw	214	15	tissues	tissue	NNS
cord-018042-qt7055fw	214	16	following	follow	VBG
cord-018042-qt7055fw	214	17	organspecific	organspecific	JJ
cord-018042-qt7055fw	214	18	transgene	transgene	NN
cord-018042-qt7055fw	214	19	driven	drive	VBN
cord-018042-qt7055fw	214	20	chemokine	chemokine	NN
cord-018042-qt7055fw	214	21	production	production	NN
cord-018042-qt7055fw	215	1	indicates	indicate	VBZ
cord-018042-qt7055fw	215	2	that	that	IN
cord-018042-qt7055fw	215	3	tissue	tissue	NN
cord-018042-qt7055fw	215	4	-	-	HYPH
cord-018042-qt7055fw	215	5	specific	specific	JJ
cord-018042-qt7055fw	215	6	influences	influence	NNS
cord-018042-qt7055fw	215	7	can	can	MD
cord-018042-qt7055fw	215	8	clearly	clearly	RB
cord-018042-qt7055fw	215	9	determine	determine	VB
cord-018042-qt7055fw	215	10	how	how	WRB
cord-018042-qt7055fw	215	11	a	a	DT
cord-018042-qt7055fw	215	12	chemokine	chemokine	NN
cord-018042-qt7055fw	215	13	will	will	MD
cord-018042-qt7055fw	215	14	behave	behave	VB
cord-018042-qt7055fw	215	15	in	in	IN
cord-018042-qt7055fw	215	16	that	that	DT
cord-018042-qt7055fw	215	17	milieu	milieu	NN
cord-018042-qt7055fw	215	18	.	.	.
cord-018042-qt7055fw	216	1	There	there	EX
cord-018042-qt7055fw	216	2	are	be	VBP
cord-018042-qt7055fw	216	3	still	still	RB
cord-018042-qt7055fw	216	4	considerable	considerable	JJ
cord-018042-qt7055fw	216	5	gaps	gap	NNS
cord-018042-qt7055fw	216	6	in	in	IN
cord-018042-qt7055fw	216	7	our	-PRON-	PRP$
cord-018042-qt7055fw	216	8	understanding	understanding	NN
cord-018042-qt7055fw	216	9	of	of	IN
cord-018042-qt7055fw	216	10	chemokine	chemokine	NN
cord-018042-qt7055fw	216	11	biology	biology	NN
cord-018042-qt7055fw	216	12	and	and	CC
cord-018042-qt7055fw	216	13	neurobiology	neurobiology	NN
cord-018042-qt7055fw	216	14	.	.	.
cord-018042-qt7055fw	217	1	However	however	RB
cord-018042-qt7055fw	217	2	,	,	,
cord-018042-qt7055fw	217	3	ongoing	ongoing	JJ
cord-018042-qt7055fw	217	4	and	and	CC
cord-018042-qt7055fw	217	5	future	future	JJ
cord-018042-qt7055fw	217	6	studies	study	NNS
cord-018042-qt7055fw	217	7	employing	employ	VBG
cord-018042-qt7055fw	217	8	approaches	approach	NNS
cord-018042-qt7055fw	217	9	such	such	JJ
cord-018042-qt7055fw	217	10	as	as	IN
cord-018042-qt7055fw	217	11	transgenic	transgenic	JJ
cord-018042-qt7055fw	217	12	modeling	modeling	NN
cord-018042-qt7055fw	217	13	no	no	DT
cord-018042-qt7055fw	217	14	doubt	doubt	NN
cord-018042-qt7055fw	217	15	will	will	MD
cord-018042-qt7055fw	217	16	begin	begin	VB
cord-018042-qt7055fw	217	17	to	to	TO
cord-018042-qt7055fw	217	18	fill	fill	VB
cord-018042-qt7055fw	217	19	these	these	DT
cord-018042-qt7055fw	217	20	gaps	gap	NNS
cord-018042-qt7055fw	217	21	.	.	.
cord-018042-qt7055fw	218	1	Functional	functional	JJ
cord-018042-qt7055fw	218	2	expression	expression	NN
cord-018042-qt7055fw	218	3	of	of	IN
cord-018042-qt7055fw	218	4	the	the	DT
cord-018042-qt7055fw	218	5	lymphoid	lymphoid	JJ
cord-018042-qt7055fw	218	6	chemokines	chemokines	NNPS
cord-018042-qt7055fw	218	7	CCL19	CCL19	NNP
cord-018042-qt7055fw	218	8	(	(	-LRB-
cord-018042-qt7055fw	218	9	ELC	ELC	NNP
cord-018042-qt7055fw	218	10	)	)	-RRB-
cord-018042-qt7055fw	218	11	and	and	CC
cord-018042-qt7055fw	218	12	CCL	CCL	NNP
cord-018042-qt7055fw	218	13	21	21	CD
cord-018042-qt7055fw	218	14	(	(	-LRB-
cord-018042-qt7055fw	218	15	SLC	SLC	NNP
cord-018042-qt7055fw	218	16	)	)	-RRB-
cord-018042-qt7055fw	218	17	at	at	IN
cord-018042-qt7055fw	218	18	the	the	DT
cord-018042-qt7055fw	218	19	blood	blood	NN
cord-018042-qt7055fw	218	20	-	-	HYPH
cord-018042-qt7055fw	218	21	brain	brain	NN
cord-018042-qt7055fw	218	22	barrier	barrier	NN
cord-018042-qt7055fw	218	23	suggests	suggest	VBZ
cord-018042-qt7055fw	218	24	their	-PRON-	PRP$
cord-018042-qt7055fw	218	25	involvement	involvement	NN
cord-018042-qt7055fw	218	26	in	in	IN
cord-018042-qt7055fw	218	27	G	g	NN
cord-018042-qt7055fw	218	28	-	-	HYPH
cord-018042-qt7055fw	218	29	protein	protein	NN
cord-018042-qt7055fw	218	30	-	-	HYPH
cord-018042-qt7055fw	218	31	dependent	dependent	JJ
cord-018042-qt7055fw	218	32	lymphocyte	lymphocyte	NN
cord-018042-qt7055fw	218	33	recruitment	recruitment	NN
cord-018042-qt7055fw	218	34	into	into	IN
cord-018042-qt7055fw	218	35	the	the	DT
cord-018042-qt7055fw	218	36	central	central	JJ
cord-018042-qt7055fw	218	37	nervous	nervous	JJ
cord-018042-qt7055fw	218	38	system	system	NN
cord-018042-qt7055fw	218	39	during	during	IN
cord-018042-qt7055fw	218	40	experimental	experimental	JJ
cord-018042-qt7055fw	218	41	autoimmune	autoimmune	JJ
cord-018042-qt7055fw	218	42	encephalomyelitis	encephalomyelitis	NN
cord-018042-qt7055fw	218	43	Chemokines	Chemokines	NNPS
cord-018042-qt7055fw	218	44	in	in	IN
cord-018042-qt7055fw	218	45	the	the	DT
cord-018042-qt7055fw	218	46	CNS	CNS	NNP
cord-018042-qt7055fw	218	47	:	:	:
cord-018042-qt7055fw	218	48	plurifunctional	plurifunctional	JJ
cord-018042-qt7055fw	218	49	mediators	mediator	NNS
cord-018042-qt7055fw	218	50	in	in	IN
cord-018042-qt7055fw	218	51	diverse	diverse	JJ
cord-018042-qt7055fw	218	52	states	state	NNS
cord-018042-qt7055fw	218	53	Distribution	distribution	NN
cord-018042-qt7055fw	218	54	,	,	,
cord-018042-qt7055fw	218	55	cellular	cellular	JJ
cord-018042-qt7055fw	218	56	localization	localization	NN
cord-018042-qt7055fw	218	57	and	and	CC
cord-018042-qt7055fw	218	58	functional	functional	JJ
cord-018042-qt7055fw	218	59	role	role	NN
cord-018042-qt7055fw	218	60	of	of	IN
cord-018042-qt7055fw	218	61	CCR2	CCR2	NNP
cord-018042-qt7055fw	218	62	chemokine	chemokine	NN
cord-018042-qt7055fw	218	63	receptors	receptor	NNS
cord-018042-qt7055fw	218	64	in	in	IN
cord-018042-qt7055fw	218	65	adult	adult	NN
cord-018042-qt7055fw	218	66	rat	rat	NN
cord-018042-qt7055fw	218	67	brain	brain	NN
cord-018042-qt7055fw	218	68	Ischemia	ischemia	NN
cord-018042-qt7055fw	218	69	-	-	HYPH
cord-018042-qt7055fw	218	70	induced	induce	VBN
cord-018042-qt7055fw	218	71	neuronal	neuronal	JJ
cord-018042-qt7055fw	218	72	expression	expression	NN
cord-018042-qt7055fw	218	73	of	of	IN
cord-018042-qt7055fw	218	74	the	the	DT
cord-018042-qt7055fw	218	75	microglia	microglia	NN
cord-018042-qt7055fw	218	76	attracting	attract	VBG
cord-018042-qt7055fw	218	77	chemokine	chemokine	JJ
cord-018042-qt7055fw	218	78	secondary	secondary	JJ
cord-018042-qt7055fw	218	79	lymphoid	lymphoid	JJ
cord-018042-qt7055fw	218	80	-	-	HYPH
cord-018042-qt7055fw	218	81	tissue	tissue	NN
cord-018042-qt7055fw	218	82	chemokine	chemokine	NN
cord-018042-qt7055fw	218	83	(	(	-LRB-
cord-018042-qt7055fw	218	84	SLC	SLC	NNP
cord-018042-qt7055fw	218	85	)	)	-RRB-
cord-018042-qt7055fw	219	1	Functional	functional	JJ
cord-018042-qt7055fw	219	2	expression	expression	NN
cord-018042-qt7055fw	219	3	of	of	IN
cord-018042-qt7055fw	219	4	CXCR3	cxcr3	NN
cord-018042-qt7055fw	219	5	in	in	IN
cord-018042-qt7055fw	219	6	cultured	cultured	JJ
cord-018042-qt7055fw	219	7	mouse	mouse	NN
cord-018042-qt7055fw	219	8	and	and	CC
cord-018042-qt7055fw	219	9	human	human	NN
cord-018042-qt7055fw	219	10	astrocytes	astrocyte	NNS
cord-018042-qt7055fw	219	11	and	and	CC
cord-018042-qt7055fw	219	12	microglia	microglia	JJ
cord-018042-qt7055fw	219	13	Leukocyte	Leukocyte	NNP
cord-018042-qt7055fw	219	14	infiltration	infiltration	NN
cord-018042-qt7055fw	219	15	,	,	,
cord-018042-qt7055fw	219	16	but	but	CC
cord-018042-qt7055fw	219	17	not	not	RB
cord-018042-qt7055fw	219	18	neurodegeneration	neurodegeneration	NN
cord-018042-qt7055fw	219	19	,	,	,
cord-018042-qt7055fw	219	20	in	in	IN
cord-018042-qt7055fw	219	21	the	the	DT
cord-018042-qt7055fw	219	22	CNS	CNS	NNP
cord-018042-qt7055fw	219	23	of	of	IN
cord-018042-qt7055fw	219	24	transgenic	transgenic	JJ
cord-018042-qt7055fw	219	25	mice	mouse	NNS
cord-018042-qt7055fw	219	26	with	with	IN
cord-018042-qt7055fw	219	27	astrocyte	astrocyte	JJ
cord-018042-qt7055fw	219	28	production	production	NN
cord-018042-qt7055fw	219	29	of	of	IN
cord-018042-qt7055fw	219	30	the	the	DT
cord-018042-qt7055fw	219	31	CXC	CXC	NNP
cord-018042-qt7055fw	219	32	chemokine	chemokine	NN
cord-018042-qt7055fw	219	33	ligand	ligand	NN
cord-018042-qt7055fw	219	34	10	10	CD
cord-018042-qt7055fw	219	35	Transgenic	transgenic	JJ
cord-018042-qt7055fw	219	36	modeling	modeling	NN
cord-018042-qt7055fw	219	37	of	of	IN
cord-018042-qt7055fw	219	38	neuropsychiatric	neuropsychiatric	JJ
cord-018042-qt7055fw	219	39	disorders	disorder	NNS
cord-018042-qt7055fw	220	1	Transgenic	transgenic	JJ
cord-018042-qt7055fw	220	2	models	model	NNS
cord-018042-qt7055fw	220	3	to	to	TO
cord-018042-qt7055fw	220	4	study	study	VB
cord-018042-qt7055fw	220	5	the	the	DT
cord-018042-qt7055fw	220	6	actions	action	NNS
cord-018042-qt7055fw	220	7	of	of	IN
cord-018042-qt7055fw	220	8	cytokines	cytokine	NNS
cord-018042-qt7055fw	220	9	in	in	IN
cord-018042-qt7055fw	220	10	the	the	DT
cord-018042-qt7055fw	220	11	central	central	JJ
cord-018042-qt7055fw	220	12	nervous	nervous	JJ
cord-018042-qt7055fw	220	13	system	system	NN
cord-018042-qt7055fw	220	14	Chemokine	Chemokine	NNP
cord-018042-qt7055fw	220	15	receptors	receptor	NNS
cord-018042-qt7055fw	220	16	in	in	IN
cord-018042-qt7055fw	220	17	the	the	DT
cord-018042-qt7055fw	220	18	central	central	JJ
cord-018042-qt7055fw	220	19	nervous	nervous	JJ
cord-018042-qt7055fw	220	20	system	system	NN
cord-018042-qt7055fw	220	21	:	:	:
cord-018042-qt7055fw	220	22	role	role	NN
cord-018042-qt7055fw	220	23	in	in	IN
cord-018042-qt7055fw	220	24	brain	brain	NN
cord-018042-qt7055fw	220	25	inflammation	inflammation	NN
cord-018042-qt7055fw	220	26	and	and	CC
cord-018042-qt7055fw	220	27	neurodegenerative	neurodegenerative	JJ
cord-018042-qt7055fw	220	28	diseases	disease	NNS
cord-018042-qt7055fw	221	1	The	the	DT
cord-018042-qt7055fw	221	2	many	many	JJ
cord-018042-qt7055fw	221	3	roles	role	NNS
cord-018042-qt7055fw	221	4	of	of	IN
cord-018042-qt7055fw	221	5	chemokines	chemokine	NNS
cord-018042-qt7055fw	221	6	and	and	CC
cord-018042-qt7055fw	221	7	chemokine	chemokine	NN
cord-018042-qt7055fw	221	8	receptors	receptor	NNS
cord-018042-qt7055fw	221	9	in	in	IN
cord-018042-qt7055fw	221	10	inflammation	inflammation	NN
cord-018042-qt7055fw	221	11	Central	central	JJ
cord-018042-qt7055fw	221	12	nervous	nervous	JJ
cord-018042-qt7055fw	221	13	system	system	NN
cord-018042-qt7055fw	221	14	inflammation	inflammation	NN
cord-018042-qt7055fw	221	15	and	and	CC
cord-018042-qt7055fw	221	16	neurological	neurological	JJ
cord-018042-qt7055fw	221	17	disease	disease	NN
cord-018042-qt7055fw	221	18	in	in	IN
cord-018042-qt7055fw	221	19	transgenic	transgenic	JJ
cord-018042-qt7055fw	221	20	mice	mouse	NNS
cord-018042-qt7055fw	221	21	expressing	express	VBG
cord-018042-qt7055fw	221	22	the	the	DT
cord-018042-qt7055fw	221	23	CC	CC	NNP
cord-018042-qt7055fw	221	24	chemokine	chemokine	NN
cord-018042-qt7055fw	221	25	CCL21	ccl21	NN
cord-018042-qt7055fw	221	26	in	in	IN
cord-018042-qt7055fw	221	27	oligodendrocytes	oligodendrocyte	NNS
cord-018042-qt7055fw	221	28	Ectopic	ectopic	JJ
cord-018042-qt7055fw	221	29	expression	expression	NN
cord-018042-qt7055fw	221	30	of	of	IN
cord-018042-qt7055fw	221	31	the	the	DT
cord-018042-qt7055fw	221	32	murine	murine	JJ
cord-018042-qt7055fw	221	33	chemokines	chemokine	NNS
cord-018042-qt7055fw	221	34	CCL21a	ccl21a	CD
cord-018042-qt7055fw	221	35	and	and	CC
cord-018042-qt7055fw	221	36	CCL21b	CCL21b	NNP
cord-018042-qt7055fw	221	37	induces	induce	VBZ
cord-018042-qt7055fw	221	38	the	the	DT
cord-018042-qt7055fw	221	39	formation	formation	NN
cord-018042-qt7055fw	221	40	of	of	IN
cord-018042-qt7055fw	221	41	lymph	lymph	NN
cord-018042-qt7055fw	221	42	node	node	NN
cord-018042-qt7055fw	221	43	-	-	HYPH
cord-018042-qt7055fw	221	44	like	like	JJ
cord-018042-qt7055fw	221	45	structures	structure	NNS
cord-018042-qt7055fw	221	46	in	in	IN
cord-018042-qt7055fw	221	47	pancreas	pancreas	NN
cord-018042-qt7055fw	221	48	,	,	,
cord-018042-qt7055fw	221	49	but	but	CC
cord-018042-qt7055fw	221	50	not	not	RB
cord-018042-qt7055fw	221	51	skin	skin	NN
cord-018042-qt7055fw	221	52	,	,	,
cord-018042-qt7055fw	221	53	of	of	IN
cord-018042-qt7055fw	221	54	transgenic	transgenic	JJ
cord-018042-qt7055fw	221	55	mice	mouse	NNS
cord-018042-qt7055fw	222	1	Interferon	interferon	NN
cord-018042-qt7055fw	222	2	-	-	HYPH
cord-018042-qt7055fw	222	3	inducible	inducible	JJ
cord-018042-qt7055fw	222	4	T	T	NNP
cord-018042-qt7055fw	222	5	cell	cell	NN
cord-018042-qt7055fw	222	6	alpha	alpha	NN
cord-018042-qt7055fw	222	7	chemoattractant	chemoattractant	NN
cord-018042-qt7055fw	222	8	(	(	-LRB-
cord-018042-qt7055fw	222	9	I	I	NNP
cord-018042-qt7055fw	222	10	-	-	HYPH
cord-018042-qt7055fw	222	11	TAC	TAC	NNP
cord-018042-qt7055fw	222	12	)	)	-RRB-
cord-018042-qt7055fw	222	13	:	:	:
cord-018042-qt7055fw	222	14	a	a	DT
cord-018042-qt7055fw	222	15	novel	novel	JJ
cord-018042-qt7055fw	222	16	non	non	JJ
cord-018042-qt7055fw	222	17	-	-	JJ
cord-018042-qt7055fw	222	18	ELR	ELR	NNP
cord-018042-qt7055fw	222	19	CXC	CXC	NNP
cord-018042-qt7055fw	222	20	chemokine	chemokine	NN
cord-018042-qt7055fw	222	21	with	with	IN
cord-018042-qt7055fw	222	22	potent	potent	JJ
cord-018042-qt7055fw	222	23	activity	activity	NN
cord-018042-qt7055fw	222	24	on	on	IN
cord-018042-qt7055fw	222	25	activated	activate	VBN
cord-018042-qt7055fw	222	26	T	T	NNP
cord-018042-qt7055fw	222	27	cells	cell	NNS
cord-018042-qt7055fw	222	28	through	through	IN
cord-018042-qt7055fw	222	29	selective	selective	JJ
cord-018042-qt7055fw	222	30	high	high	JJ
cord-018042-qt7055fw	222	31	affinity	affinity	NN
cord-018042-qt7055fw	222	32	binding	bind	VBG
cord-018042-qt7055fw	222	33	to	to	IN
cord-018042-qt7055fw	222	34	CXCR3	cxcr3	XX
cord-018042-qt7055fw	223	1	Monocyte	Monocyte	NNP
cord-018042-qt7055fw	223	2	chemoattractant	chemoattractant	NN
cord-018042-qt7055fw	223	3	protein-1	protein-1	NNP
cord-018042-qt7055fw	223	4	(	(	-LRB-
cord-018042-qt7055fw	223	5	CCL2	CCL2	NNP
cord-018042-qt7055fw	223	6	)	)	-RRB-
cord-018042-qt7055fw	223	7	in	in	IN
cord-018042-qt7055fw	223	8	inflammatory	inflammatory	JJ
cord-018042-qt7055fw	223	9	disease	disease	NN
cord-018042-qt7055fw	223	10	and	and	CC
cord-018042-qt7055fw	223	11	adaptive	adaptive	JJ
cord-018042-qt7055fw	223	12	immunity	immunity	NN
cord-018042-qt7055fw	223	13	:	:	:
cord-018042-qt7055fw	224	1	therapeutic	therapeutic	JJ
cord-018042-qt7055fw	224	2	opportunities	opportunity	NNS
cord-018042-qt7055fw	224	3	and	and	CC
cord-018042-qt7055fw	224	4	controversies	controversy	NNS
cord-018042-qt7055fw	224	5	Widely	widely	RB
cord-018042-qt7055fw	224	6	expressed	express	VBD
cord-018042-qt7055fw	224	7	transcripts	transcript	NNS
cord-018042-qt7055fw	224	8	for	for	IN
cord-018042-qt7055fw	224	9	chemokine	chemokine	NN
cord-018042-qt7055fw	224	10	receptor	receptor	NN
cord-018042-qt7055fw	224	11	CXCR1	cxcr1	NN
cord-018042-qt7055fw	224	12	in	in	IN
cord-018042-qt7055fw	224	13	identified	identify	VBN
cord-018042-qt7055fw	224	14	glutamatergic	glutamatergic	JJ
cord-018042-qt7055fw	224	15	,	,	,
cord-018042-qt7055fw	224	16	gamma	gamma	NN
cord-018042-qt7055fw	224	17	-	-	HYPH
cord-018042-qt7055fw	224	18	aminobutyric	aminobutyric	NN
cord-018042-qt7055fw	224	19	acidergic	acidergic	NNP
cord-018042-qt7055fw	224	20	,	,	,
cord-018042-qt7055fw	224	21	and	and	CC
cord-018042-qt7055fw	224	22	cholinergic	cholinergic	JJ
cord-018042-qt7055fw	224	23	neurons	neuron	NNS
cord-018042-qt7055fw	224	24	and	and	CC
cord-018042-qt7055fw	224	25	astrocytes	astrocyte	NNS
cord-018042-qt7055fw	224	26	of	of	IN
cord-018042-qt7055fw	224	27	the	the	DT
cord-018042-qt7055fw	224	28	rat	rat	NN
cord-018042-qt7055fw	224	29	brain	brain	NN
cord-018042-qt7055fw	224	30	:	:	:
cord-018042-qt7055fw	224	31	a	a	DT
cord-018042-qt7055fw	224	32	single	single	JJ
cord-018042-qt7055fw	224	33	-	-	HYPH
cord-018042-qt7055fw	224	34	cell	cell	NN
cord-018042-qt7055fw	224	35	reverse	reverse	NN
cord-018042-qt7055fw	224	36	transcription	transcription	NN
cord-018042-qt7055fw	224	37	-	-	HYPH
cord-018042-qt7055fw	224	38	multiplex	multiplex	NN
cord-018042-qt7055fw	224	39	polymerase	polymerase	NN
cord-018042-qt7055fw	224	40	chain	chain	NN
cord-018042-qt7055fw	224	41	reaction	reaction	NN
cord-018042-qt7055fw	224	42	study	study	NN
cord-018042-qt7055fw	224	43	Transgenic	transgenic	JJ
cord-018042-qt7055fw	224	44	expression	expression	NN
cord-018042-qt7055fw	224	45	of	of	IN
cord-018042-qt7055fw	224	46	CCL2	CCL2	NNP
cord-018042-qt7055fw	224	47	in	in	IN
cord-018042-qt7055fw	224	48	the	the	DT
cord-018042-qt7055fw	224	49	central	central	JJ
cord-018042-qt7055fw	224	50	nervous	nervous	JJ
cord-018042-qt7055fw	224	51	system	system	NN
cord-018042-qt7055fw	224	52	prevents	prevent	VBZ
cord-018042-qt7055fw	224	53	experimental	experimental	JJ
cord-018042-qt7055fw	224	54	autoimmune	autoimmune	JJ
cord-018042-qt7055fw	224	55	encephalomyelitis	encephalomyelitis	NN
cord-018042-qt7055fw	224	56	Molecular	Molecular	NNP
cord-018042-qt7055fw	224	57	mechanisms	mechanism	NNS
cord-018042-qt7055fw	224	58	involved	involve	VBN
cord-018042-qt7055fw	224	59	in	in	IN
cord-018042-qt7055fw	224	60	T	T	NNP
cord-018042-qt7055fw	224	61	cell	cell	NN
cord-018042-qt7055fw	224	62	migration	migration	NN
cord-018042-qt7055fw	224	63	across	across	IN
cord-018042-qt7055fw	224	64	the	the	DT
cord-018042-qt7055fw	224	65	blood	blood	NN
cord-018042-qt7055fw	224	66	-	-	HYPH
cord-018042-qt7055fw	224	67	brain	brain	NN
cord-018042-qt7055fw	224	68	barrier	barrier	NN
cord-018042-qt7055fw	224	69	Cutting	cut	VBG
cord-018042-qt7055fw	224	70	edge	edge	NN
cord-018042-qt7055fw	224	71	:	:	:
cord-018042-qt7055fw	224	72	ectopic	ectopic	JJ
cord-018042-qt7055fw	224	73	expression	expression	NN
cord-018042-qt7055fw	224	74	of	of	IN
cord-018042-qt7055fw	224	75	the	the	DT
cord-018042-qt7055fw	224	76	chemokine	chemokine	NN
cord-018042-qt7055fw	224	77	TCA4	TCA4	NNP
cord-018042-qt7055fw	224	78	/	/	SYM
cord-018042-qt7055fw	224	79	SLC	SLC	NNP
cord-018042-qt7055fw	224	80	is	be	VBZ
cord-018042-qt7055fw	224	81	sufficient	sufficient	JJ
cord-018042-qt7055fw	224	82	to	to	TO
cord-018042-qt7055fw	224	83	trigger	trigger	VB
cord-018042-qt7055fw	224	84	lymphoid	lymphoid	JJ
cord-018042-qt7055fw	224	85	neogenesis	neogenesis	NNP
cord-018042-qt7055fw	224	86	CC	CC	NNP
cord-018042-qt7055fw	224	87	chemokine	chemokine	NN
cord-018042-qt7055fw	224	88	receptor	receptor	NN
cord-018042-qt7055fw	224	89	2	2	CD
cord-018042-qt7055fw	224	90	is	be	VBZ
cord-018042-qt7055fw	224	91	critical	critical	JJ
cord-018042-qt7055fw	224	92	for	for	IN
cord-018042-qt7055fw	224	93	induction	induction	NN
cord-018042-qt7055fw	224	94	of	of	IN
cord-018042-qt7055fw	224	95	experimental	experimental	JJ
cord-018042-qt7055fw	224	96	autoimmune	autoimmune	JJ
cord-018042-qt7055fw	224	97	encephalomyelitis	encephalomyelitis	NN
cord-018042-qt7055fw	224	98	GRO	gro	NN
cord-018042-qt7055fw	224	99	-	-	HYPH
cord-018042-qt7055fw	224	100	alpha	alpha	NN
cord-018042-qt7055fw	224	101	and	and	CC
cord-018042-qt7055fw	224	102	CXCR2	CXCR2	NNS
cord-018042-qt7055fw	224	103	in	in	IN
cord-018042-qt7055fw	224	104	the	the	DT
cord-018042-qt7055fw	224	105	human	human	JJ
cord-018042-qt7055fw	224	106	fetal	fetal	JJ
cord-018042-qt7055fw	224	107	brain	brain	NN
cord-018042-qt7055fw	224	108	and	and	CC
cord-018042-qt7055fw	224	109	multiple	multiple	JJ
cord-018042-qt7055fw	224	110	sclerosis	sclerosis	NN
cord-018042-qt7055fw	224	111	lesions	lesion	NNS
cord-018042-qt7055fw	224	112	Regulation	Regulation	NNP
cord-018042-qt7055fw	224	113	of	of	IN
cord-018042-qt7055fw	224	114	chemokine	chemokine	JJ
cord-018042-qt7055fw	224	115	receptor	receptor	NN
cord-018042-qt7055fw	224	116	expression	expression	NN
cord-018042-qt7055fw	224	117	in	in	IN
cord-018042-qt7055fw	224	118	human	human	JJ
cord-018042-qt7055fw	224	119	microglia	microglia	NNS
cord-018042-qt7055fw	224	120	and	and	CC
cord-018042-qt7055fw	224	121	astrocytes	astrocyte	VBZ
cord-018042-qt7055fw	224	122	CCR7	CCR7	NNP
cord-018042-qt7055fw	224	123	coordinates	coordinate	VBZ
cord-018042-qt7055fw	224	124	the	the	DT
cord-018042-qt7055fw	224	125	primary	primary	JJ
cord-018042-qt7055fw	224	126	immune	immune	JJ
cord-018042-qt7055fw	224	127	response	response	NN
cord-018042-qt7055fw	224	128	by	by	IN
cord-018042-qt7055fw	224	129	establishing	establish	VBG
cord-018042-qt7055fw	224	130	functional	functional	JJ
cord-018042-qt7055fw	224	131	microenvironments	microenvironment	NNS
cord-018042-qt7055fw	224	132	in	in	IN
cord-018042-qt7055fw	224	133	secondary	secondary	JJ
cord-018042-qt7055fw	224	134	lymphoid	lymphoid	JJ
cord-018042-qt7055fw	224	135	organs	organ	NNS
cord-018042-qt7055fw	224	136	Controlled	control	VBN
cord-018042-qt7055fw	224	137	recruitment	recruitment	NN
cord-018042-qt7055fw	224	138	of	of	IN
cord-018042-qt7055fw	224	139	monocytes	monocyte	NNS
cord-018042-qt7055fw	224	140	and	and	CC
cord-018042-qt7055fw	224	141	macrophages	macrophage	NNS
cord-018042-qt7055fw	224	142	to	to	IN
cord-018042-qt7055fw	224	143	specific	specific	JJ
cord-018042-qt7055fw	224	144	organs	organ	NNS
cord-018042-qt7055fw	224	145	through	through	IN
cord-018042-qt7055fw	224	146	transgenic	transgenic	JJ
cord-018042-qt7055fw	224	147	expression	expression	NN
cord-018042-qt7055fw	224	148	of	of	IN
cord-018042-qt7055fw	224	149	monocyte	monocyte	NNP
cord-018042-qt7055fw	224	150	chemoattractant	chemoattractant	NNP
cord-018042-qt7055fw	225	1	protein-1	protein-1	NNP
cord-018042-qt7055fw	225	2	Gene	Gene	NNP
cord-018042-qt7055fw	225	3	knock	knock	VB
cord-018042-qt7055fw	225	4	-	-	HYPH
cord-018042-qt7055fw	225	5	out	out	RP
cord-018042-qt7055fw	225	6	technology	technology	NN
cord-018042-qt7055fw	225	7	:	:	:
cord-018042-qt7055fw	226	1	a	a	DT
cord-018042-qt7055fw	226	2	methodological	methodological	JJ
cord-018042-qt7055fw	226	3	overview	overview	NN
cord-018042-qt7055fw	226	4	for	for	IN
cord-018042-qt7055fw	226	5	the	the	DT
cord-018042-qt7055fw	226	6	interested	interested	JJ
cord-018042-qt7055fw	226	7	novice	novice	NN
cord-018042-qt7055fw	226	8	CXC	CXC	NNP
cord-018042-qt7055fw	226	9	chemokines	chemokine	NNS
cord-018042-qt7055fw	226	10	interleukin-8	interleukin-8	NNP
cord-018042-qt7055fw	226	11	(	(	-LRB-
cord-018042-qt7055fw	226	12	IL-8	il-8	NN
cord-018042-qt7055fw	226	13	)	)	-RRB-
cord-018042-qt7055fw	226	14	and	and	CC
cord-018042-qt7055fw	226	15	growth	growth	NN
cord-018042-qt7055fw	226	16	-	-	HYPH
cord-018042-qt7055fw	226	17	related	relate	VBN
cord-018042-qt7055fw	226	18	gene	gene	NN
cord-018042-qt7055fw	226	19	product	product	NN
cord-018042-qt7055fw	226	20	alpha	alpha	NN
cord-018042-qt7055fw	226	21	(	(	-LRB-
cord-018042-qt7055fw	226	22	GROalpha	GROalpha	NNP
cord-018042-qt7055fw	226	23	)	)	-RRB-
cord-018042-qt7055fw	226	24	modulate	modulate	VB
cord-018042-qt7055fw	226	25	Purkinje	Purkinje	NNP
cord-018042-qt7055fw	226	26	neuron	neuron	NN
cord-018042-qt7055fw	226	27	activity	activity	NN
cord-018042-qt7055fw	226	28	in	in	IN
cord-018042-qt7055fw	226	29	mouse	mouse	NN
cord-018042-qt7055fw	226	30	cerebellum	cerebellum	NN
cord-018042-qt7055fw	226	31	Chemokine	Chemokine	NNP
cord-018042-qt7055fw	226	32	monocyte	monocyte	NNP
cord-018042-qt7055fw	227	1	chemoattractant	chemoattractant	NNP
cord-018042-qt7055fw	227	2	protein-1	protein-1	NNP
cord-018042-qt7055fw	227	3	is	be	VBZ
cord-018042-qt7055fw	227	4	expressed	express	VBN
cord-018042-qt7055fw	227	5	by	by	IN
cord-018042-qt7055fw	227	6	astrocytes	astrocyte	NNS
cord-018042-qt7055fw	227	7	after	after	IN
cord-018042-qt7055fw	227	8	mechanical	mechanical	JJ
cord-018042-qt7055fw	227	9	injury	injury	NN
cord-018042-qt7055fw	227	10	to	to	IN
cord-018042-qt7055fw	227	11	the	the	DT
cord-018042-qt7055fw	227	12	brain	brain	NN
cord-018042-qt7055fw	228	1	Monocyte	Monocyte	NNP
cord-018042-qt7055fw	228	2	chemoattractant	chemoattractant	NN
cord-018042-qt7055fw	228	3	protein-1	protein-1	NNP
cord-018042-qt7055fw	228	4	is	be	VBZ
cord-018042-qt7055fw	228	5	sufficient	sufficient	JJ
cord-018042-qt7055fw	228	6	for	for	IN
cord-018042-qt7055fw	228	7	the	the	DT
cord-018042-qt7055fw	228	8	chemotaxis	chemotaxis	NN
cord-018042-qt7055fw	228	9	of	of	IN
cord-018042-qt7055fw	228	10	monocytes	monocyte	NNS
cord-018042-qt7055fw	228	11	and	and	CC
cord-018042-qt7055fw	228	12	lymphocytes	lymphocyte	NNS
cord-018042-qt7055fw	228	13	in	in	IN
cord-018042-qt7055fw	228	14	transgenic	transgenic	JJ
cord-018042-qt7055fw	228	15	mice	mouse	NNS
cord-018042-qt7055fw	228	16	but	but	CC
cord-018042-qt7055fw	228	17	requires	require	VBZ
cord-018042-qt7055fw	228	18	an	an	DT
cord-018042-qt7055fw	228	19	additional	additional	JJ
cord-018042-qt7055fw	228	20	stimulus	stimulus	NN
cord-018042-qt7055fw	228	21	for	for	IN
cord-018042-qt7055fw	228	22	inflammatory	inflammatory	JJ
cord-018042-qt7055fw	228	23	activation	activation	NN
cord-018042-qt7055fw	228	24	Identification	identification	NN
cord-018042-qt7055fw	228	25	and	and	CC
cord-018042-qt7055fw	228	26	characterization	characterization	NN
cord-018042-qt7055fw	228	27	of	of	IN
cord-018042-qt7055fw	228	28	a	a	DT
cord-018042-qt7055fw	228	29	novel	novel	JJ
cord-018042-qt7055fw	228	30	beta	beta	NN
cord-018042-qt7055fw	228	31	chemokine	chemokine	NN
cord-018042-qt7055fw	228	32	containing	contain	VBG
cord-018042-qt7055fw	228	33	six	six	CD
cord-018042-qt7055fw	228	34	conserved	conserved	JJ
cord-018042-qt7055fw	228	35	cysteines	cysteine	NNS
cord-018042-qt7055fw	228	36	Cytokines	Cytokines	NNPS
cord-018042-qt7055fw	228	37	and	and	CC
cord-018042-qt7055fw	228	38	the	the	DT
cord-018042-qt7055fw	228	39	nervous	nervous	JJ
cord-018042-qt7055fw	228	40	system	system	NN
cord-018042-qt7055fw	228	41	.	.	.
cord-018042-qt7055fw	229	1	I	-PRON-	PRP
cord-018042-qt7055fw	229	2	:	:	:
cord-018042-qt7055fw	229	3	expression	expression	NN
cord-018042-qt7055fw	229	4	and	and	CC
cord-018042-qt7055fw	229	5	recognition	recognition	NN
cord-018042-qt7055fw	229	6	Expression	expression	NN
cord-018042-qt7055fw	229	7	of	of	IN
cord-018042-qt7055fw	229	8	chemokine	chemokine	NN
cord-018042-qt7055fw	229	9	receptors	receptor	NNS
cord-018042-qt7055fw	229	10	by	by	IN
cord-018042-qt7055fw	229	11	subsets	subset	NNS
cord-018042-qt7055fw	229	12	of	of	IN
cord-018042-qt7055fw	229	13	neurons	neuron	NNS
cord-018042-qt7055fw	229	14	in	in	IN
cord-018042-qt7055fw	230	1	the	the	DT
cord-018042-qt7055fw	230	2	central	central	JJ
cord-018042-qt7055fw	230	3	nervous	nervous	JJ
cord-018042-qt7055fw	230	4	system	system	NN
cord-018042-qt7055fw	230	5	Pertussis	pertussis	NN
cord-018042-qt7055fw	230	6	toxin	toxin	NN
cord-018042-qt7055fw	230	7	-	-	HYPH
cord-018042-qt7055fw	230	8	induced	induce	VBN
cord-018042-qt7055fw	230	9	reversible	reversible	JJ
cord-018042-qt7055fw	230	10	encephalopathy	encephalopathy	NN
cord-018042-qt7055fw	230	11	dependent	dependent	JJ
cord-018042-qt7055fw	230	12	on	on	IN
cord-018042-qt7055fw	230	13	monocyte	monocyte	NNP
cord-018042-qt7055fw	231	1	chemoattractant	chemoattractant	NNP
cord-018042-qt7055fw	231	2	protein-1	protein-1	NNP
cord-018042-qt7055fw	231	3	overexpression	overexpression	NN
cord-018042-qt7055fw	231	4	in	in	IN
cord-018042-qt7055fw	231	5	mice	mouse	NNS
cord-018042-qt7055fw	231	6	Chronic	chronic	JJ
cord-018042-qt7055fw	231	7	expression	expression	NN
cord-018042-qt7055fw	231	8	of	of	IN
cord-018042-qt7055fw	231	9	monocyte	monocyte	NNP
cord-018042-qt7055fw	231	10	chemoattractant	chemoattractant	NNP
cord-018042-qt7055fw	231	11	protein-1	protein-1	NNP
cord-018042-qt7055fw	231	12	in	in	IN
cord-018042-qt7055fw	231	13	the	the	DT
cord-018042-qt7055fw	231	14	central	central	JJ
cord-018042-qt7055fw	231	15	nervous	nervous	JJ
cord-018042-qt7055fw	231	16	system	system	NN
cord-018042-qt7055fw	232	1	causes	cause	NNS
cord-018042-qt7055fw	232	2	delayed	delay	VBN
cord-018042-qt7055fw	232	3	encephalopathy	encephalopathy	NN
cord-018042-qt7055fw	232	4	and	and	CC
cord-018042-qt7055fw	232	5	impaired	impair	VBN
cord-018042-qt7055fw	232	6	microglial	microglial	JJ
cord-018042-qt7055fw	232	7	function	function	NN
cord-018042-qt7055fw	232	8	in	in	IN
cord-018042-qt7055fw	232	9	mice	mouse	NNS
cord-018042-qt7055fw	233	1	The	the	DT
cord-018042-qt7055fw	233	2	CC	cc	NN
cord-018042-qt7055fw	233	3	chemokine	chemokine	NN
cord-018042-qt7055fw	233	4	receptor-7	receptor-7	NNP
cord-018042-qt7055fw	233	5	ligands	ligand	NNS
cord-018042-qt7055fw	233	6	6Ckine	6Ckine	NNP
cord-018042-qt7055fw	233	7	and	and	CC
cord-018042-qt7055fw	233	8	macrophage	macrophage	NN
cord-018042-qt7055fw	234	1	inflammatory	inflammatory	JJ
cord-018042-qt7055fw	234	2	protein-3	protein-3	NNP
cord-018042-qt7055fw	235	1	beta	beta	NN
cord-018042-qt7055fw	235	2	are	be	VBP
cord-018042-qt7055fw	235	3	potent	potent	JJ
cord-018042-qt7055fw	235	4	chemoattractants	chemoattractant	NNS
cord-018042-qt7055fw	235	5	for	for	IN
cord-018042-qt7055fw	235	6	in	in	FW
cord-018042-qt7055fw	235	7	vitro	vitro	FW
cord-018042-qt7055fw	235	8	-	-	:
cord-018042-qt7055fw	235	9	and	and	CC
cord-018042-qt7055fw	235	10	in	in	IN
cord-018042-qt7055fw	235	11	vivo	vivo	NN
cord-018042-qt7055fw	235	12	-	-	HYPH
cord-018042-qt7055fw	235	13	derived	derive	VBN
cord-018042-qt7055fw	235	14	dendritic	dendritic	JJ
cord-018042-qt7055fw	235	15	cells	cell	NNS
cord-018042-qt7055fw	235	16	Regulation	regulation	NN
cord-018042-qt7055fw	235	17	of	of	IN
cord-018042-qt7055fw	235	18	neuroinflammation	neuroinflammation	NN
cord-018042-qt7055fw	235	19	:	:	:
cord-018042-qt7055fw	236	1	the	the	DT
cord-018042-qt7055fw	236	2	role	role	NN
cord-018042-qt7055fw	236	3	of	of	IN
cord-018042-qt7055fw	236	4	CXCL10	CXCL10	NNP
cord-018042-qt7055fw	236	5	in	in	IN
cord-018042-qt7055fw	236	6	lymphocyte	lymphocyte	NN
cord-018042-qt7055fw	236	7	infiltration	infiltration	NN
cord-018042-qt7055fw	236	8	during	during	IN
cord-018042-qt7055fw	236	9	autoimmune	autoimmune	JJ
cord-018042-qt7055fw	236	10	encephalomyelitis	encephalomyelitis	NN
cord-018042-qt7055fw	236	11	IFN	IFN	NNP
cord-018042-qt7055fw	236	12	-	-	HYPH
cord-018042-qt7055fw	236	13	inducible	inducible	JJ
cord-018042-qt7055fw	236	14	protein	protein	NN
cord-018042-qt7055fw	236	15	10	10	CD
cord-018042-qt7055fw	236	16	/	/	SYM
cord-018042-qt7055fw	236	17	CXC	CXC	NNP
cord-018042-qt7055fw	236	18	chemokine	chemokine	NN
cord-018042-qt7055fw	236	19	ligand	ligand	NN
cord-018042-qt7055fw	236	20	10-independent	10-independent	CD
cord-018042-qt7055fw	236	21	induction	induction	NN
cord-018042-qt7055fw	236	22	of	of	IN
cord-018042-qt7055fw	236	23	experimental	experimental	JJ
cord-018042-qt7055fw	236	24	autoimmune	autoimmune	JJ
cord-018042-qt7055fw	236	25	encephalomyelitis	encephalomyelitis	NN
cord-018042-qt7055fw	236	26	Human	Human	NNP
cord-018042-qt7055fw	236	27	mig	mig	NNP
cord-018042-qt7055fw	236	28	chemokine	chemokine	NN
cord-018042-qt7055fw	236	29	:	:	:
cord-018042-qt7055fw	236	30	biochemical	biochemical	JJ
cord-018042-qt7055fw	236	31	and	and	CC
cord-018042-qt7055fw	236	32	functional	functional	JJ
cord-018042-qt7055fw	236	33	characterization	characterization	NN
cord-018042-qt7055fw	236	34	Chemokine	Chemokine	NNP
cord-018042-qt7055fw	236	35	receptor	receptor	NN
cord-018042-qt7055fw	237	1	CXCR3	cxcr3	XX
cord-018042-qt7055fw	237	2	:	:	:
cord-018042-qt7055fw	238	1	an	an	DT
cord-018042-qt7055fw	238	2	unexpected	unexpected	JJ
cord-018042-qt7055fw	238	3	enigma	enigma	NN
cord-018042-qt7055fw	238	4	Chemokine	Chemokine	NNP
cord-018042-qt7055fw	238	5	receptor	receptor	NN
cord-018042-qt7055fw	238	6	specific	specific	JJ
cord-018042-qt7055fw	238	7	for	for	IN
cord-018042-qt7055fw	238	8	IP10	IP10	NNP
cord-018042-qt7055fw	238	9	and	and	CC
cord-018042-qt7055fw	238	10	mig	mig	NNP
cord-018042-qt7055fw	238	11	:	:	:
cord-018042-qt7055fw	238	12	structure	structure	NN
cord-018042-qt7055fw	238	13	,	,	,
cord-018042-qt7055fw	238	14	function	function	NN
cord-018042-qt7055fw	238	15	,	,	,
cord-018042-qt7055fw	238	16	and	and	CC
cord-018042-qt7055fw	238	17	expression	expression	NN
cord-018042-qt7055fw	238	18	in	in	IN
cord-018042-qt7055fw	238	19	activated	activate	VBN
cord-018042-qt7055fw	238	20	T	T	NNP
cord-018042-qt7055fw	238	21	-	-	HYPH
cord-018042-qt7055fw	238	22	lymphocytes	lymphocyte	NNS
cord-018042-qt7055fw	238	23	Chemokines	Chemokines	NNPS
cord-018042-qt7055fw	238	24	and	and	CC
cord-018042-qt7055fw	238	25	chemokine	chemokine	NN
cord-018042-qt7055fw	238	26	receptors	receptor	NNS
cord-018042-qt7055fw	238	27	in	in	IN
cord-018042-qt7055fw	238	28	the	the	DT
cord-018042-qt7055fw	238	29	CNS	CNS	NNP
cord-018042-qt7055fw	238	30	:	:	:
cord-018042-qt7055fw	238	31	a	a	DT
cord-018042-qt7055fw	238	32	possible	possible	JJ
cord-018042-qt7055fw	238	33	role	role	NN
cord-018042-qt7055fw	238	34	in	in	IN
cord-018042-qt7055fw	238	35	neuroinflammation	neuroinflammation	NN
cord-018042-qt7055fw	238	36	and	and	CC
cord-018042-qt7055fw	238	37	patterning	pattern	VBG
cord-018042-qt7055fw	238	38	Molecular	molecular	JJ
cord-018042-qt7055fw	238	39	cloning	cloning	NN
cord-018042-qt7055fw	238	40	of	of	IN
cord-018042-qt7055fw	238	41	a	a	DT
cord-018042-qt7055fw	238	42	novel	novel	JJ
cord-018042-qt7055fw	238	43	human	human	NN
cord-018042-qt7055fw	238	44	CC	cc	NN
cord-018042-qt7055fw	238	45	chemokine	chemokine	NN
cord-018042-qt7055fw	238	46	secondary	secondary	JJ
cord-018042-qt7055fw	238	47	lymphoid	lymphoid	JJ
cord-018042-qt7055fw	238	48	-	-	HYPH
cord-018042-qt7055fw	238	49	tissue	tissue	NN
cord-018042-qt7055fw	238	50	chemokine	chemokine	NN
cord-018042-qt7055fw	238	51	that	that	WDT
cord-018042-qt7055fw	238	52	is	be	VBZ
cord-018042-qt7055fw	238	53	a	a	DT
cord-018042-qt7055fw	238	54	potent	potent	JJ
cord-018042-qt7055fw	238	55	chemoattractant	chemoattractant	NN
cord-018042-qt7055fw	238	56	for	for	IN
cord-018042-qt7055fw	238	57	lymphocytes	lymphocyte	NNS
cord-018042-qt7055fw	238	58	and	and	CC
cord-018042-qt7055fw	238	59	mapped	map	VBN
cord-018042-qt7055fw	238	60	to	to	TO
cord-018042-qt7055fw	238	61	chromosome	chromosome	NN
cord-018042-qt7055fw	238	62	9p13	9p13	CD
cord-018042-qt7055fw	239	1	The	the	DT
cord-018042-qt7055fw	239	2	chemokine	chemokine	NN
cord-018042-qt7055fw	239	3	CXCL10	CXCL10	NNP
cord-018042-qt7055fw	239	4	modulates	modulate	VBZ
cord-018042-qt7055fw	239	5	excitatory	excitatory	JJ
cord-018042-qt7055fw	239	6	activity	activity	NN
cord-018042-qt7055fw	239	7	and	and	CC
cord-018042-qt7055fw	239	8	intracellular	intracellular	JJ
cord-018042-qt7055fw	239	9	calcium	calcium	NN
cord-018042-qt7055fw	239	10	signaling	signal	VBG
cord-018042-qt7055fw	239	11	in	in	IN
cord-018042-qt7055fw	239	12	cultured	cultured	JJ
cord-018042-qt7055fw	239	13	hippocampal	hippocampal	JJ
cord-018042-qt7055fw	239	14	neurons	neuron	NNS
cord-018042-qt7055fw	239	15	Expression	expression	NN
cord-018042-qt7055fw	239	16	of	of	IN
cord-018042-qt7055fw	239	17	the	the	DT
cord-018042-qt7055fw	239	18	chemokine	chemokine	NN
cord-018042-qt7055fw	239	19	receptors	receptor	NNS
cord-018042-qt7055fw	239	20	CXCR1	CXCR1	NNS
cord-018042-qt7055fw	239	21	and	and	CC
cord-018042-qt7055fw	239	22	CXCR2	CXCR2	NNS
cord-018042-qt7055fw	239	23	in	in	IN
cord-018042-qt7055fw	239	24	rat	rat	NN
cord-018042-qt7055fw	239	25	oligodendroglial	oligodendroglial	JJ
cord-018042-qt7055fw	239	26	cells	cell	NNS
cord-018042-qt7055fw	239	27	Role	role	NN
cord-018042-qt7055fw	239	28	for	for	IN
cord-018042-qt7055fw	239	29	CXCR2	CXCR2	NNS
cord-018042-qt7055fw	239	30	and	and	CC
cord-018042-qt7055fw	239	31	CXCL1	CXCL1	NNP
cord-018042-qt7055fw	239	32	on	on	IN
cord-018042-qt7055fw	239	33	glia	glia	NNS
cord-018042-qt7055fw	239	34	in	in	IN
cord-018042-qt7055fw	239	35	multiple	multiple	JJ
cord-018042-qt7055fw	239	36	sclerosis	sclerosis	NN
cord-018042-qt7055fw	239	37	Alterations	alteration	NNS
cord-018042-qt7055fw	239	38	in	in	IN
cord-018042-qt7055fw	239	39	the	the	DT
cord-018042-qt7055fw	239	40	oligodendrocyte	oligodendrocyte	NNP
cord-018042-qt7055fw	239	41	lineage	lineage	NN
cord-018042-qt7055fw	239	42	,	,	,
cord-018042-qt7055fw	239	43	myelin	myelin	NN
cord-018042-qt7055fw	239	44	,	,	,
cord-018042-qt7055fw	239	45	and	and	CC
cord-018042-qt7055fw	239	46	white	white	JJ
cord-018042-qt7055fw	239	47	matter	matter	NN
cord-018042-qt7055fw	239	48	in	in	IN
cord-018042-qt7055fw	239	49	adult	adult	NN
cord-018042-qt7055fw	239	50	mice	mouse	NNS
cord-018042-qt7055fw	239	51	lacking	lack	VBG
cord-018042-qt7055fw	240	1	the	the	DT
cord-018042-qt7055fw	240	2	chemokine	chemokine	NN
cord-018042-qt7055fw	240	3	receptor	receptor	NN
cord-018042-qt7055fw	240	4	CXCR2	CXCR2	.
cord-018042-qt7055fw	240	5	Experimental	experimental	JJ
cord-018042-qt7055fw	240	6	autoimmune	autoimmune	JJ
cord-018042-qt7055fw	240	7	encephalomyelitis	encephalomyelitis	NN
cord-018042-qt7055fw	240	8	develops	develop	VBZ
cord-018042-qt7055fw	240	9	in	in	IN
cord-018042-qt7055fw	240	10	CC	CC	NNP
cord-018042-qt7055fw	240	11	chemokine	chemokine	NN
cord-018042-qt7055fw	240	12	receptor	receptor	NN
cord-018042-qt7055fw	240	13	7-deficient	7-deficient	CD
cord-018042-qt7055fw	240	14	mice	mouse	NNS
cord-018042-qt7055fw	240	15	with	with	IN
cord-018042-qt7055fw	240	16	altered	alter	VBN
cord-018042-qt7055fw	240	17	T	t	NN
cord-018042-qt7055fw	240	18	-	-	HYPH
cord-018042-qt7055fw	240	19	cell	cell	NN
cord-018042-qt7055fw	240	20	responses	response	NNS
cord-018042-qt7055fw	240	21	Modulation	modulation	NN
cord-018042-qt7055fw	240	22	of	of	IN
cord-018042-qt7055fw	240	23	the	the	DT
cord-018042-qt7055fw	240	24	neurotransmitter	neurotransmitter	NN
cord-018042-qt7055fw	240	25	release	release	NN
cord-018042-qt7055fw	240	26	in	in	IN
cord-018042-qt7055fw	240	27	rat	rat	NN
cord-018042-qt7055fw	240	28	cerebellar	cerebellar	JJ
cord-018042-qt7055fw	240	29	neurons	neuron	NNS
cord-018042-qt7055fw	240	30	by	by	IN
cord-018042-qt7055fw	240	31	GRO	GRO	NNP
cord-018042-qt7055fw	240	32	beta	beta	NN
cord-018042-qt7055fw	241	1	The	the	DT
cord-018042-qt7055fw	241	2	chemokine	chemokine	NN
cord-018042-qt7055fw	241	3	system	system	NN
cord-018042-qt7055fw	241	4	in	in	IN
cord-018042-qt7055fw	241	5	neuroinflammation	neuroinflammation	NN
cord-018042-qt7055fw	241	6	:	:	:
cord-018042-qt7055fw	242	1	an	an	DT
cord-018042-qt7055fw	242	2	update	update	NN
cord-018042-qt7055fw	242	3	Astrocyte	Astrocyte	NNP
cord-018042-qt7055fw	242	4	expression	expression	NN
cord-018042-qt7055fw	242	5	of	of	IN
cord-018042-qt7055fw	242	6	mRNA	mrna	NN
cord-018042-qt7055fw	242	7	encoding	encode	VBG
cord-018042-qt7055fw	242	8	cytokines	cytokine	NNS
cord-018042-qt7055fw	242	9	IP-10	IP-10	NNP
cord-018042-qt7055fw	242	10	and	and	CC
cord-018042-qt7055fw	242	11	JE	JE	NNP
cord-018042-qt7055fw	242	12	/	/	SYM
cord-018042-qt7055fw	242	13	MCP-1	MCP-1	NNP
cord-018042-qt7055fw	242	14	in	in	IN
cord-018042-qt7055fw	242	15	experimental	experimental	JJ
cord-018042-qt7055fw	242	16	autoimmune	autoimmune	JJ
cord-018042-qt7055fw	242	17	encephalomyelitis	encephalomyelitis	NN
cord-018042-qt7055fw	242	18	Secondary	secondary	JJ
cord-018042-qt7055fw	242	19	lymphoid	lymphoid	JJ
cord-018042-qt7055fw	242	20	tissue	tissue	NN
cord-018042-qt7055fw	242	21	chemokine	chemokine	NN
cord-018042-qt7055fw	242	22	(	(	-LRB-
cord-018042-qt7055fw	242	23	CCL21	CCL21	NNP
cord-018042-qt7055fw	242	24	)	)	-RRB-
cord-018042-qt7055fw	242	25	activates	activate	VBZ
cord-018042-qt7055fw	242	26	CXCR3	cxcr3	XX
cord-018042-qt7055fw	242	27	to	to	TO
cord-018042-qt7055fw	242	28	trigger	trigger	VB
cord-018042-qt7055fw	242	29	a	a	DT
cord-018042-qt7055fw	242	30	Cl	Cl	NNP
cord-018042-qt7055fw	242	31	-	-	HYPH
cord-018042-qt7055fw	242	32	current	current	JJ
cord-018042-qt7055fw	242	33	and	and	CC
cord-018042-qt7055fw	242	34	chemotaxis	chemotaxis	NN
cord-018042-qt7055fw	242	35	in	in	IN
cord-018042-qt7055fw	242	36	murine	murine	JJ
cord-018042-qt7055fw	242	37	microglia	microglia	NNP
cord-018042-qt7055fw	242	38	CXCR3-dependent	CXCR3-dependent	NNP
cord-018042-qt7055fw	242	39	microglial	microglial	JJ
cord-018042-qt7055fw	242	40	recruitment	recruitment	NN
cord-018042-qt7055fw	242	41	is	be	VBZ
cord-018042-qt7055fw	242	42	essential	essential	JJ
cord-018042-qt7055fw	242	43	for	for	IN
cord-018042-qt7055fw	242	44	dendrite	dendrite	NN
cord-018042-qt7055fw	242	45	loss	loss	NN
cord-018042-qt7055fw	242	46	after	after	IN
cord-018042-qt7055fw	242	47	brain	brain	NN
cord-018042-qt7055fw	242	48	lesion	lesion	NN
cord-018042-qt7055fw	242	49	Chemokines	Chemokines	NNPS
cord-018042-qt7055fw	242	50	,	,	,
cord-018042-qt7055fw	242	51	mononuclear	mononuclear	NN
cord-018042-qt7055fw	242	52	cells	cell	NNS
cord-018042-qt7055fw	242	53	and	and	CC
cord-018042-qt7055fw	242	54	the	the	DT
cord-018042-qt7055fw	242	55	nervous	nervous	JJ
cord-018042-qt7055fw	242	56	system	system	NN
cord-018042-qt7055fw	242	57	:	:	:
cord-018042-qt7055fw	242	58	heaven	heaven	NNP
cord-018042-qt7055fw	242	59	(	(	-LRB-
cord-018042-qt7055fw	242	60	or	or	CC
cord-018042-qt7055fw	242	61	hell	hell	NNP
cord-018042-qt7055fw	242	62	)	)	-RRB-
cord-018042-qt7055fw	242	63	is	be	VBZ
cord-018042-qt7055fw	242	64	in	in	IN
cord-018042-qt7055fw	242	65	the	the	DT
cord-018042-qt7055fw	242	66	details	detail	NNS
cord-018042-qt7055fw	242	67	Islet	islet	NN
cord-018042-qt7055fw	242	68	-	-	HYPH
cord-018042-qt7055fw	242	69	specific	specific	JJ
cord-018042-qt7055fw	242	70	expression	expression	NN
cord-018042-qt7055fw	242	71	of	of	IN
cord-018042-qt7055fw	242	72	CXCL10	CXCL10	NNP
cord-018042-qt7055fw	242	73	causes	cause	VBZ
cord-018042-qt7055fw	242	74	spontaneous	spontaneous	JJ
cord-018042-qt7055fw	242	75	islet	islet	NN
cord-018042-qt7055fw	242	76	infiltration	infiltration	NN
cord-018042-qt7055fw	242	77	and	and	CC
cord-018042-qt7055fw	242	78	accelerates	accelerate	VBZ
cord-018042-qt7055fw	242	79	diabetes	diabetes	NN
cord-018042-qt7055fw	243	1	development	development	NNP
cord-018042-qt7055fw	243	2	JE	JE	NNP
cord-018042-qt7055fw	243	3	/	/	SYM
cord-018042-qt7055fw	243	4	MCP-1	MCP-1	NNP
cord-018042-qt7055fw	243	5	:	:	:
cord-018042-qt7055fw	244	1	an	an	DT
cord-018042-qt7055fw	244	2	early	early	JJ
cord-018042-qt7055fw	244	3	-	-	HYPH
cord-018042-qt7055fw	244	4	response	response	NN
cord-018042-qt7055fw	244	5	gene	gene	NN
cord-018042-qt7055fw	244	6	encodes	encode	VBZ
cord-018042-qt7055fw	245	1	a	a	DT
cord-018042-qt7055fw	245	2	monocyte	monocyte	JJ
cord-018042-qt7055fw	245	3	-	-	HYPH
cord-018042-qt7055fw	245	4	specific	specific	JJ
cord-018042-qt7055fw	245	5	cytokine	cytokine	NN
cord-018042-qt7055fw	245	6	Recombinant	recombinant	JJ
cord-018042-qt7055fw	245	7	human	human	NN
cord-018042-qt7055fw	245	8	MCP-1	MCP-1	NNP
cord-018042-qt7055fw	245	9	/	/	SYM
cord-018042-qt7055fw	245	10	JE	JE	NNP
cord-018042-qt7055fw	245	11	induces	induce	VBZ
cord-018042-qt7055fw	245	12	chemotaxis	chemotaxis	NN
cord-018042-qt7055fw	245	13	,	,	,
cord-018042-qt7055fw	245	14	calcium	calcium	NN
cord-018042-qt7055fw	245	15	flux	flux	NN
cord-018042-qt7055fw	245	16	,	,	,
cord-018042-qt7055fw	245	17	and	and	CC
cord-018042-qt7055fw	245	18	the	the	DT
cord-018042-qt7055fw	245	19	respiratory	respiratory	JJ
cord-018042-qt7055fw	245	20	burst	burst	NN
cord-018042-qt7055fw	245	21	in	in	IN
cord-018042-qt7055fw	245	22	human	human	JJ
cord-018042-qt7055fw	245	23	monocytes	monocyte	NNS
cord-018042-qt7055fw	245	24	Chemokines	Chemokines	NNPS
cord-018042-qt7055fw	245	25	in	in	IN
cord-018042-qt7055fw	245	26	innate	innate	JJ
cord-018042-qt7055fw	245	27	and	and	CC
cord-018042-qt7055fw	245	28	adaptive	adaptive	JJ
cord-018042-qt7055fw	245	29	host	host	NN
cord-018042-qt7055fw	245	30	defense	defense	NN
cord-018042-qt7055fw	245	31	:	:	:
cord-018042-qt7055fw	245	32	basic	basic	JJ
cord-018042-qt7055fw	245	33	chemokinese	chemokinese	NN
cord-018042-qt7055fw	245	34	grammar	grammar	NN
cord-018042-qt7055fw	245	35	for	for	IN
cord-018042-qt7055fw	245	36	immune	immune	JJ
cord-018042-qt7055fw	245	37	cells	cell	NNS
cord-018042-qt7055fw	245	38	T	T	NNP
cord-018042-qt7055fw	245	39	helper	helper	NN
cord-018042-qt7055fw	245	40	1	1	CD
cord-018042-qt7055fw	245	41	and	and	CC
cord-018042-qt7055fw	245	42	T	T	NNP
cord-018042-qt7055fw	245	43	helper	helper	NN
cord-018042-qt7055fw	245	44	2	2	CD
cord-018042-qt7055fw	245	45	cells	cell	NNS
cord-018042-qt7055fw	245	46	respond	respond	VBP
cord-018042-qt7055fw	245	47	differentially	differentially	RB
cord-018042-qt7055fw	245	48	to	to	IN
cord-018042-qt7055fw	245	49	chemokines	chemokine	NNS
cord-018042-qt7055fw	246	1	A	a	DT
cord-018042-qt7055fw	246	2	functional	functional	JJ
cord-018042-qt7055fw	246	3	IFN	IFN	NNP
cord-018042-qt7055fw	246	4	-	-	HYPH
cord-018042-qt7055fw	246	5	gamma	gamma	NN
cord-018042-qt7055fw	246	6	-	-	HYPH
cord-018042-qt7055fw	246	7	inducible	inducible	JJ
cord-018042-qt7055fw	246	8	protein-10	protein-10	CD
cord-018042-qt7055fw	246	9	/	/	SYM
cord-018042-qt7055fw	246	10	CXCL10-specific	CXCL10-specific	NNP
cord-018042-qt7055fw	246	11	receptor	receptor	NN
cord-018042-qt7055fw	246	12	expressed	express	VBN
cord-018042-qt7055fw	246	13	by	by	IN
cord-018042-qt7055fw	246	14	epithelial	epithelial	JJ
cord-018042-qt7055fw	246	15	and	and	CC
cord-018042-qt7055fw	246	16	endothelial	endothelial	JJ
cord-018042-qt7055fw	246	17	cells	cell	NNS
cord-018042-qt7055fw	246	18	that	that	WDT
cord-018042-qt7055fw	246	19	is	be	VBZ
cord-018042-qt7055fw	247	1	neither	neither	CC
cord-018042-qt7055fw	247	2	CXCR3	cxcr3	XX
cord-018042-qt7055fw	247	3	nor	nor	CC
cord-018042-qt7055fw	247	4	glycosaminoglycan	glycosaminoglycan	NNP
cord-018042-qt7055fw	247	5	T	T	NNP
cord-018042-qt7055fw	247	6	cell	cell	NN
cord-018042-qt7055fw	247	7	antiviral	antiviral	JJ
cord-018042-qt7055fw	247	8	effector	effector	NN
cord-018042-qt7055fw	247	9	function	function	NN
cord-018042-qt7055fw	247	10	is	be	VBZ
cord-018042-qt7055fw	247	11	not	not	RB
cord-018042-qt7055fw	247	12	dependent	dependent	JJ
cord-018042-qt7055fw	247	13	on	on	IN
cord-018042-qt7055fw	248	1	CXCL10	cxcl10	LS
cord-018042-qt7055fw	248	2	following	follow	VBG
cord-018042-qt7055fw	248	3	murine	murine	JJ
cord-018042-qt7055fw	248	4	coronavirus	coronavirus	NN
cord-018042-qt7055fw	248	5	infection	infection	NN
cord-018042-qt7055fw	248	6	Neutrophil	Neutrophil	NNP
cord-018042-qt7055fw	248	7	infiltration	infiltration	NN
cord-018042-qt7055fw	248	8	,	,	,
cord-018042-qt7055fw	248	9	glial	glial	JJ
cord-018042-qt7055fw	248	10	reaction	reaction	NN
cord-018042-qt7055fw	248	11	,	,	,
cord-018042-qt7055fw	248	12	and	and	CC
cord-018042-qt7055fw	248	13	neurological	neurological	JJ
cord-018042-qt7055fw	248	14	disease	disease	NN
cord-018042-qt7055fw	248	15	in	in	IN
cord-018042-qt7055fw	248	16	transgenic	transgenic	JJ
cord-018042-qt7055fw	248	17	mice	mouse	NNS
cord-018042-qt7055fw	248	18	expressing	express	VBG
cord-018042-qt7055fw	248	19	the	the	DT
cord-018042-qt7055fw	248	20	chemokine	chemokine	NN
cord-018042-qt7055fw	248	21	N51	N51	NNP
cord-018042-qt7055fw	248	22	/	/	SYM
cord-018042-qt7055fw	248	23	KC	KC	NNP
cord-018042-qt7055fw	248	24	in	in	IN
cord-018042-qt7055fw	248	25	oligodendrocytes	oligodendrocytes	NNPS
cord-018042-qt7055fw	249	1	The	the	DT
cord-018042-qt7055fw	249	2	effects	effect	NNS
cord-018042-qt7055fw	249	3	of	of	IN
cord-018042-qt7055fw	249	4	human	human	JJ
cord-018042-qt7055fw	249	5	recombinant	recombinant	JJ
cord-018042-qt7055fw	249	6	MIP-1	MIP-1	NNP
cord-018042-qt7055fw	249	7	alpha	alpha	NN
cord-018042-qt7055fw	249	8	,	,	,
cord-018042-qt7055fw	249	9	MIP-1	MIP-1	NNP
cord-018042-qt7055fw	249	10	beta	beta	NN
cord-018042-qt7055fw	249	11	,	,	,
cord-018042-qt7055fw	249	12	and	and	CC
cord-018042-qt7055fw	249	13	RANTES	RANTES	NNPS
cord-018042-qt7055fw	249	14	on	on	IN
cord-018042-qt7055fw	249	15	the	the	DT
cord-018042-qt7055fw	249	16	chemotaxis	chemotaxis	NN
cord-018042-qt7055fw	249	17	and	and	CC
cord-018042-qt7055fw	249	18	adhesion	adhesion	NN
cord-018042-qt7055fw	249	19	of	of	IN
cord-018042-qt7055fw	249	20	T	T	NNP
cord-018042-qt7055fw	249	21	cell	cell	NN
cord-018042-qt7055fw	249	22	subsets	subset	NNS
cord-018042-qt7055fw	250	1	Human	human	JJ
cord-018042-qt7055fw	250	2	interferon	interferon	NN
cord-018042-qt7055fw	250	3	-	-	HYPH
cord-018042-qt7055fw	250	4	inducible	inducible	JJ
cord-018042-qt7055fw	250	5	protein-10	protein-10	CD
cord-018042-qt7055fw	250	6	induces	induce	VBZ
cord-018042-qt7055fw	250	7	mononuclear	mononuclear	JJ
cord-018042-qt7055fw	250	8	cell	cell	NN
cord-018042-qt7055fw	250	9	infiltration	infiltration	NN
cord-018042-qt7055fw	250	10	in	in	IN
cord-018042-qt7055fw	250	11	mice	mouse	NNS
cord-018042-qt7055fw	250	12	and	and	CC
cord-018042-qt7055fw	250	13	promotes	promote	VBZ
cord-018042-qt7055fw	250	14	the	the	DT
cord-018042-qt7055fw	250	15	migration	migration	NN
cord-018042-qt7055fw	250	16	of	of	IN
cord-018042-qt7055fw	250	17	human	human	JJ
cord-018042-qt7055fw	250	18	T	t	NN
cord-018042-qt7055fw	250	19	lymphocytes	lymphocyte	NNS
cord-018042-qt7055fw	250	20	into	into	IN
cord-018042-qt7055fw	250	21	the	the	DT
cord-018042-qt7055fw	250	22	peripheral	peripheral	JJ
cord-018042-qt7055fw	250	23	tissues	tissue	NNS
cord-018042-qt7055fw	250	24	and	and	CC
cord-018042-qt7055fw	250	25	human	human	JJ
cord-018042-qt7055fw	250	26	peripheral	peripheral	JJ
cord-018042-qt7055fw	250	27	blood	blood	NN
cord-018042-qt7055fw	250	28	lymphocytes	lymphocyte	NNS
cord-018042-qt7055fw	251	1	-SCID	-SCID	:
cord-018042-qt7055fw	251	2	mice	mouse	NNS
cord-018042-qt7055fw	252	1	Beta	beta	NN
cord-018042-qt7055fw	252	2	chemokines	chemokine	NNS
cord-018042-qt7055fw	253	1	costimulate	costimulate	NNP
cord-018042-qt7055fw	253	2	lymphocyte	lymphocyte	NN
cord-018042-qt7055fw	253	3	cytolysis	cytolysis	NN
cord-018042-qt7055fw	253	4	,	,	,
cord-018042-qt7055fw	253	5	proliferation	proliferation	NN
cord-018042-qt7055fw	253	6	,	,	,
cord-018042-qt7055fw	253	7	and	and	CC
cord-018042-qt7055fw	253	8	lymphokine	lymphokine	NN
cord-018042-qt7055fw	253	9	production	production	NN
cord-018042-qt7055fw	253	10	Metalloproteinases	Metalloproteinases	NNPS
cord-018042-qt7055fw	253	11	control	control	VBP
cord-018042-qt7055fw	253	12	brain	brain	NN
cord-018042-qt7055fw	253	13	inflammation	inflammation	NN
cord-018042-qt7055fw	253	14	induced	induce	VBN
cord-018042-qt7055fw	253	15	by	by	IN
cord-018042-qt7055fw	253	16	pertussis	pertussis	NN
cord-018042-qt7055fw	253	17	toxin	toxin	NN
cord-018042-qt7055fw	253	18	in	in	IN
cord-018042-qt7055fw	253	19	mice	mouse	NNS
cord-018042-qt7055fw	253	20	overexpressing	overexpresse	VBG
cord-018042-qt7055fw	253	21	the	the	DT
cord-018042-qt7055fw	253	22	chemokine	chemokine	NN
cord-018042-qt7055fw	253	23	CCL2	CCL2	NNP
cord-018042-qt7055fw	253	24	in	in	IN
cord-018042-qt7055fw	253	25	the	the	DT
cord-018042-qt7055fw	253	26	central	central	JJ
cord-018042-qt7055fw	253	27	nervous	nervous	JJ
cord-018042-qt7055fw	253	28	system	system	NN
cord-018042-qt7055fw	253	29	The	the	DT
cord-018042-qt7055fw	253	30	expression	expression	NN
cord-018042-qt7055fw	253	31	and	and	CC
cord-018042-qt7055fw	253	32	function	function	NN
cord-018042-qt7055fw	253	33	of	of	IN
cord-018042-qt7055fw	253	34	chemokines	chemokine	NNS
cord-018042-qt7055fw	253	35	involved	involve	VBN
cord-018042-qt7055fw	253	36	in	in	IN
cord-018042-qt7055fw	253	37	CNS	CNS	NNP
cord-018042-qt7055fw	253	38	inflammation	inflammation	NN
cord-018042-qt7055fw	253	39	Acute	acute	JJ
cord-018042-qt7055fw	253	40	exposure	exposure	NN
cord-018042-qt7055fw	253	41	to	to	IN
cord-018042-qt7055fw	253	42	CXC	CXC	NNP
cord-018042-qt7055fw	253	43	chemokine	chemokine	NN
cord-018042-qt7055fw	253	44	ligand	ligand	NN
cord-018042-qt7055fw	253	45	10	10	CD
cord-018042-qt7055fw	253	46	,	,	,
cord-018042-qt7055fw	253	47	but	but	CC
cord-018042-qt7055fw	253	48	not	not	RB
cord-018042-qt7055fw	253	49	its	-PRON-	PRP$
cord-018042-qt7055fw	253	50	chronic	chronic	JJ
cord-018042-qt7055fw	253	51	astroglial	astroglial	JJ
cord-018042-qt7055fw	253	52	production	production	NN
cord-018042-qt7055fw	253	53	,	,	,
cord-018042-qt7055fw	253	54	alters	alter	VBZ
cord-018042-qt7055fw	253	55	synaptic	synaptic	JJ
cord-018042-qt7055fw	253	56	plasticity	plasticity	NN
cord-018042-qt7055fw	253	57	in	in	IN
cord-018042-qt7055fw	253	58	mouse	mouse	NN
cord-018042-qt7055fw	253	59	hippocampal	hippocampal	JJ
cord-018042-qt7055fw	253	60	slices	slice	NNS
cord-018042-qt7055fw	254	1	Overexpression	Overexpression	NNP
cord-018042-qt7055fw	254	2	of	of	IN
cord-018042-qt7055fw	254	3	monocyte	monocyte	NNP
cord-018042-qt7055fw	254	4	chemotactic	chemotactic	NNP
cord-018042-qt7055fw	254	5	protein-1	protein-1	NNP
cord-018042-qt7055fw	254	6	/	/	SYM
cord-018042-qt7055fw	254	7	CCL2	CCL2	NNP
cord-018042-qt7055fw	254	8	in	in	IN
cord-018042-qt7055fw	254	9	beta	beta	JJ
cord-018042-qt7055fw	254	10	-	-	HYPH
cord-018042-qt7055fw	254	11	amyloid	amyloid	NN
cord-018042-qt7055fw	254	12	precursor	precursor	NN
cord-018042-qt7055fw	254	13	protein	protein	NN
cord-018042-qt7055fw	254	14	transgenic	transgenic	JJ
cord-018042-qt7055fw	254	15	mice	mouse	NNS
cord-018042-qt7055fw	254	16	show	show	VBP
cord-018042-qt7055fw	254	17	accelerated	accelerate	VBN
cord-018042-qt7055fw	254	18	diffuse	diffuse	JJ
cord-018042-qt7055fw	254	19	beta	beta	NN
cord-018042-qt7055fw	254	20	-	-	HYPH
cord-018042-qt7055fw	254	21	amyloid	amyloid	NN
cord-018042-qt7055fw	254	22	deposition	deposition	NN
cord-018042-qt7055fw	255	1	The	the	DT
cord-018042-qt7055fw	255	2	authors	author	NNS
cord-018042-qt7055fw	255	3	studies	study	NNS
cord-018042-qt7055fw	255	4	referred	refer	VBD
cord-018042-qt7055fw	255	5	to	to	IN
cord-018042-qt7055fw	255	6	in	in	IN
cord-018042-qt7055fw	255	7	this	this	DT
cord-018042-qt7055fw	255	8	article	article	NN
cord-018042-qt7055fw	255	9	were	be	VBD
cord-018042-qt7055fw	255	10	funded	fund	VBN
cord-018042-qt7055fw	255	11	by	by	IN
cord-018042-qt7055fw	255	12	USPHS	USPHS	NNP
cord-018042-qt7055fw	255	13	grants	grant	NNS
cord-018042-qt7055fw	255	14	MH	MH	NNP
cord-018042-qt7055fw	255	15	62231	62231	CD
cord-018042-qt7055fw	255	16	and	and	CC
cord-018042-qt7055fw	255	17	NS044905	NS044905	NNP
cord-018042-qt7055fw	255	18	.	.	.