id	sid	tid	token	lemma	pos
cord-330553-sukrjl22	1	1	key	key	NN
cord-330553-sukrjl22	1	2	:	:	:
cord-330553-sukrjl22	1	3	cord-330553-sukrjl22	cord-330553-sukrjl22	NNP
cord-330553-sukrjl22	1	4	authors	author	NNS
cord-330553-sukrjl22	1	5	:	:	:
cord-330553-sukrjl22	1	6	Stonedahl	Stonedahl	NNPS
cord-330553-sukrjl22	1	7	,	,	,
cord-330553-sukrjl22	1	8	Sarah	Sarah	NNP
cord-330553-sukrjl22	1	9	;	;	:
cord-330553-sukrjl22	1	10	Clarke	Clarke	NNP
cord-330553-sukrjl22	1	11	,	,	,
cord-330553-sukrjl22	1	12	Penny	Penny	NNP
cord-330553-sukrjl22	1	13	;	;	:
cord-330553-sukrjl22	1	14	Tyler	Tyler	NNP
cord-330553-sukrjl22	1	15	,	,	,
cord-330553-sukrjl22	1	16	Kenneth	Kenneth	NNP
cord-330553-sukrjl22	1	17	L.	L.	NNP
cord-330553-sukrjl22	1	18	title	title	NN
cord-330553-sukrjl22	1	19	:	:	:
cord-330553-sukrjl22	2	1	The	the	DT
cord-330553-sukrjl22	2	2	Role	role	NN
cord-330553-sukrjl22	2	3	of	of	IN
cord-330553-sukrjl22	2	4	Microglia	Microglia	NNP
cord-330553-sukrjl22	2	5	during	during	IN
cord-330553-sukrjl22	2	6	West	West	NNP
cord-330553-sukrjl22	2	7	Nile	Nile	NNP
cord-330553-sukrjl22	2	8	Virus	Virus	NNP
cord-330553-sukrjl22	2	9	Infection	Infection	NNP
cord-330553-sukrjl22	2	10	of	of	IN
cord-330553-sukrjl22	2	11	the	the	DT
cord-330553-sukrjl22	2	12	Central	Central	NNP
cord-330553-sukrjl22	2	13	Nervous	Nervous	NNP
cord-330553-sukrjl22	2	14	System	System	NNP
cord-330553-sukrjl22	2	15	date	date	NN
cord-330553-sukrjl22	2	16	:	:	:
cord-330553-sukrjl22	2	17	2020	2020	CD
cord-330553-sukrjl22	2	18	-	-	HYPH
cord-330553-sukrjl22	2	19	08	08	CD
cord-330553-sukrjl22	2	20	-	-	HYPH
cord-330553-sukrjl22	2	21	28	28	CD
cord-330553-sukrjl22	2	22	journal	journal	NN
cord-330553-sukrjl22	2	23	:	:	:
cord-330553-sukrjl22	3	1	Vaccines	vaccine	NNS
cord-330553-sukrjl22	3	2	(	(	-LRB-
cord-330553-sukrjl22	3	3	Basel	Basel	NNP
cord-330553-sukrjl22	3	4	)	)	-RRB-
cord-330553-sukrjl22	3	5	DOI	DOI	NNP
cord-330553-sukrjl22	3	6	:	:	:
cord-330553-sukrjl22	3	7	10.3390	10.3390	CD
cord-330553-sukrjl22	3	8	/	/	SYM
cord-330553-sukrjl22	3	9	vaccines8030485	vaccines8030485	CD
cord-330553-sukrjl22	3	10	sha	sha	NNP
cord-330553-sukrjl22	3	11	:	:	:
cord-330553-sukrjl22	3	12	20406e3005ca77a7a43c3d486869e3f740e87cc7	20406e3005ca77a7a43c3d486869e3f740e87cc7	NNP
cord-330553-sukrjl22	3	13	doc_id	doc_id	NNP
cord-330553-sukrjl22	3	14	:	:	:
cord-330553-sukrjl22	3	15	330553	330553	CD
cord-330553-sukrjl22	3	16	cord_uid	cord_uid	NNS
cord-330553-sukrjl22	3	17	:	:	:
cord-330553-sukrjl22	4	1	sukrjl22	sukrjl22	NNP
cord-330553-sukrjl22	4	2	Encephalitis	encephalitis	RB
cord-330553-sukrjl22	4	3	resulting	result	VBG
cord-330553-sukrjl22	4	4	from	from	IN
cord-330553-sukrjl22	4	5	viral	viral	JJ
cord-330553-sukrjl22	4	6	infections	infection	NNS
cord-330553-sukrjl22	4	7	is	be	VBZ
cord-330553-sukrjl22	4	8	a	a	DT
cord-330553-sukrjl22	4	9	major	major	JJ
cord-330553-sukrjl22	4	10	cause	cause	NN
cord-330553-sukrjl22	4	11	of	of	IN
cord-330553-sukrjl22	4	12	hospitalization	hospitalization	NN
cord-330553-sukrjl22	4	13	and	and	CC
cord-330553-sukrjl22	4	14	death	death	NN
cord-330553-sukrjl22	4	15	worldwide	worldwide	RB
cord-330553-sukrjl22	4	16	.	.	.
cord-330553-sukrjl22	5	1	West	West	NNP
cord-330553-sukrjl22	5	2	Nile	Nile	NNP
cord-330553-sukrjl22	5	3	Virus	Virus	NNP
cord-330553-sukrjl22	5	4	(	(	-LRB-
cord-330553-sukrjl22	5	5	WNV	WNV	NNP
cord-330553-sukrjl22	5	6	)	)	-RRB-
cord-330553-sukrjl22	5	7	is	be	VBZ
cord-330553-sukrjl22	5	8	a	a	DT
cord-330553-sukrjl22	5	9	substantial	substantial	JJ
cord-330553-sukrjl22	5	10	health	health	NN
cord-330553-sukrjl22	5	11	concern	concern	NN
cord-330553-sukrjl22	5	12	as	as	IN
cord-330553-sukrjl22	5	13	it	-PRON-	PRP
cord-330553-sukrjl22	5	14	is	be	VBZ
cord-330553-sukrjl22	5	15	one	one	CD
cord-330553-sukrjl22	5	16	of	of	IN
cord-330553-sukrjl22	5	17	the	the	DT
cord-330553-sukrjl22	5	18	leading	lead	VBG
cord-330553-sukrjl22	5	19	causes	cause	NNS
cord-330553-sukrjl22	5	20	of	of	IN
cord-330553-sukrjl22	5	21	viral	viral	JJ
cord-330553-sukrjl22	5	22	encephalitis	encephalitis	RB
cord-330553-sukrjl22	5	23	in	in	IN
cord-330553-sukrjl22	5	24	the	the	DT
cord-330553-sukrjl22	5	25	United	United	NNP
cord-330553-sukrjl22	5	26	States	States	NNP
cord-330553-sukrjl22	5	27	today	today	NN
cord-330553-sukrjl22	5	28	.	.	.
cord-330553-sukrjl22	6	1	WNV	WNV	NNP
cord-330553-sukrjl22	6	2	infiltrates	infiltrate	VBZ
cord-330553-sukrjl22	6	3	the	the	DT
cord-330553-sukrjl22	6	4	central	central	JJ
cord-330553-sukrjl22	6	5	nervous	nervous	JJ
cord-330553-sukrjl22	6	6	system	system	NN
cord-330553-sukrjl22	6	7	(	(	-LRB-
cord-330553-sukrjl22	6	8	CNS	CNS	NNP
cord-330553-sukrjl22	6	9	)	)	-RRB-
cord-330553-sukrjl22	6	10	,	,	,
cord-330553-sukrjl22	6	11	where	where	WRB
cord-330553-sukrjl22	6	12	it	-PRON-	PRP
cord-330553-sukrjl22	6	13	directly	directly	RB
cord-330553-sukrjl22	6	14	infects	infect	VBZ
cord-330553-sukrjl22	6	15	neurons	neuron	NNS
cord-330553-sukrjl22	6	16	and	and	CC
cord-330553-sukrjl22	6	17	induces	induce	VBZ
cord-330553-sukrjl22	6	18	neuronal	neuronal	JJ
cord-330553-sukrjl22	6	19	cell	cell	NN
cord-330553-sukrjl22	6	20	death	death	NN
cord-330553-sukrjl22	6	21	,	,	,
cord-330553-sukrjl22	6	22	in	in	IN
cord-330553-sukrjl22	6	23	part	part	NN
cord-330553-sukrjl22	6	24	,	,	,
cord-330553-sukrjl22	6	25	via	via	IN
cord-330553-sukrjl22	6	26	activation	activation	NN
cord-330553-sukrjl22	6	27	of	of	IN
cord-330553-sukrjl22	6	28	caspase	caspase	NN
cord-330553-sukrjl22	6	29	3-mediated	3-mediated	CD
cord-330553-sukrjl22	6	30	apoptosis	apoptosis	NN
cord-330553-sukrjl22	6	31	.	.	.
cord-330553-sukrjl22	7	1	WNV	WNV	NNP
cord-330553-sukrjl22	7	2	infection	infection	NN
cord-330553-sukrjl22	7	3	also	also	RB
cord-330553-sukrjl22	7	4	induces	induce	VBZ
cord-330553-sukrjl22	7	5	neuroinflammation	neuroinflammation	NN
cord-330553-sukrjl22	7	6	characterized	characterize	VBN
cord-330553-sukrjl22	7	7	by	by	IN
cord-330553-sukrjl22	7	8	activation	activation	NN
cord-330553-sukrjl22	7	9	of	of	IN
cord-330553-sukrjl22	7	10	innate	innate	JJ
cord-330553-sukrjl22	7	11	immune	immune	JJ
cord-330553-sukrjl22	7	12	cells	cell	NNS
cord-330553-sukrjl22	7	13	,	,	,
cord-330553-sukrjl22	7	14	including	include	VBG
cord-330553-sukrjl22	7	15	microglia	microglia	NNS
cord-330553-sukrjl22	7	16	and	and	CC
cord-330553-sukrjl22	7	17	astrocytes	astrocyte	NNS
cord-330553-sukrjl22	7	18	,	,	,
cord-330553-sukrjl22	7	19	production	production	NN
cord-330553-sukrjl22	7	20	of	of	IN
cord-330553-sukrjl22	7	21	inflammatory	inflammatory	JJ
cord-330553-sukrjl22	7	22	cytokines	cytokine	NNS
cord-330553-sukrjl22	7	23	,	,	,
cord-330553-sukrjl22	7	24	breakdown	breakdown	NN
cord-330553-sukrjl22	7	25	of	of	IN
cord-330553-sukrjl22	7	26	the	the	DT
cord-330553-sukrjl22	7	27	blood	blood	NN
cord-330553-sukrjl22	7	28	-	-	HYPH
cord-330553-sukrjl22	7	29	brain	brain	NN
cord-330553-sukrjl22	7	30	barrier	barrier	NN
cord-330553-sukrjl22	7	31	,	,	,
cord-330553-sukrjl22	7	32	and	and	CC
cord-330553-sukrjl22	7	33	infiltration	infiltration	NN
cord-330553-sukrjl22	7	34	of	of	IN
cord-330553-sukrjl22	7	35	peripheral	peripheral	JJ
cord-330553-sukrjl22	7	36	leukocytes	leukocyte	NNS
cord-330553-sukrjl22	7	37	.	.	.
cord-330553-sukrjl22	8	1	Microglia	Microglia	NNP
cord-330553-sukrjl22	8	2	are	be	VBP
cord-330553-sukrjl22	8	3	the	the	DT
cord-330553-sukrjl22	8	4	resident	resident	JJ
cord-330553-sukrjl22	8	5	immune	immune	JJ
cord-330553-sukrjl22	8	6	cells	cell	NNS
cord-330553-sukrjl22	8	7	of	of	IN
cord-330553-sukrjl22	8	8	the	the	DT
cord-330553-sukrjl22	8	9	brain	brain	NN
cord-330553-sukrjl22	8	10	and	and	CC
cord-330553-sukrjl22	8	11	monitor	monitor	VB
cord-330553-sukrjl22	8	12	the	the	DT
cord-330553-sukrjl22	8	13	CNS	CNS	NNP
cord-330553-sukrjl22	8	14	for	for	IN
cord-330553-sukrjl22	8	15	signs	sign	NNS
cord-330553-sukrjl22	8	16	of	of	IN
cord-330553-sukrjl22	8	17	injury	injury	NN
cord-330553-sukrjl22	8	18	or	or	CC
cord-330553-sukrjl22	8	19	pathogens	pathogen	NNS
cord-330553-sukrjl22	8	20	.	.	.
cord-330553-sukrjl22	9	1	Following	follow	VBG
cord-330553-sukrjl22	9	2	infection	infection	NN
cord-330553-sukrjl22	9	3	with	with	IN
cord-330553-sukrjl22	9	4	WNV	WNV	NNP
cord-330553-sukrjl22	9	5	,	,	,
cord-330553-sukrjl22	9	6	microglia	microglia	NNS
cord-330553-sukrjl22	9	7	exhibit	exhibit	VBP
cord-330553-sukrjl22	9	8	a	a	DT
cord-330553-sukrjl22	9	9	change	change	NN
cord-330553-sukrjl22	9	10	in	in	IN
cord-330553-sukrjl22	9	11	morphology	morphology	NN
cord-330553-sukrjl22	9	12	consistent	consistent	JJ
cord-330553-sukrjl22	9	13	with	with	IN
cord-330553-sukrjl22	9	14	activation	activation	NN
cord-330553-sukrjl22	9	15	and	and	CC
cord-330553-sukrjl22	9	16	are	be	VBP
cord-330553-sukrjl22	9	17	associated	associate	VBN
cord-330553-sukrjl22	9	18	with	with	IN
cord-330553-sukrjl22	9	19	increased	increase	VBN
cord-330553-sukrjl22	9	20	expression	expression	NN
cord-330553-sukrjl22	9	21	of	of	IN
cord-330553-sukrjl22	9	22	proinflammatory	proinflammatory	JJ
cord-330553-sukrjl22	9	23	cytokines	cytokine	NNS
cord-330553-sukrjl22	9	24	.	.	.
cord-330553-sukrjl22	10	1	Recent	recent	JJ
cord-330553-sukrjl22	10	2	research	research	NN
cord-330553-sukrjl22	10	3	has	have	VBZ
cord-330553-sukrjl22	10	4	focused	focus	VBN
cord-330553-sukrjl22	10	5	on	on	IN
cord-330553-sukrjl22	10	6	deciphering	decipher	VBG
cord-330553-sukrjl22	10	7	the	the	DT
cord-330553-sukrjl22	10	8	role	role	NN
cord-330553-sukrjl22	10	9	of	of	IN
cord-330553-sukrjl22	10	10	microglia	microglia	NN
cord-330553-sukrjl22	10	11	during	during	IN
cord-330553-sukrjl22	10	12	WNV	WNV	NNP
cord-330553-sukrjl22	10	13	encephalitis	encephalitis	RB
cord-330553-sukrjl22	10	14	.	.	.
cord-330553-sukrjl22	11	1	Microglia	Microglia	NNP
cord-330553-sukrjl22	11	2	play	play	VBP
cord-330553-sukrjl22	11	3	a	a	DT
cord-330553-sukrjl22	11	4	protective	protective	JJ
cord-330553-sukrjl22	11	5	role	role	NN
cord-330553-sukrjl22	11	6	during	during	IN
cord-330553-sukrjl22	11	7	infections	infection	NNS
cord-330553-sukrjl22	11	8	by	by	IN
cord-330553-sukrjl22	11	9	limiting	limit	VBG
cord-330553-sukrjl22	11	10	viral	viral	JJ
cord-330553-sukrjl22	11	11	growth	growth	NN
cord-330553-sukrjl22	11	12	and	and	CC
cord-330553-sukrjl22	11	13	reducing	reduce	VBG
cord-330553-sukrjl22	11	14	mortality	mortality	NN
cord-330553-sukrjl22	11	15	in	in	IN
cord-330553-sukrjl22	11	16	mice	mouse	NNS
cord-330553-sukrjl22	11	17	.	.	.
cord-330553-sukrjl22	12	1	However	however	RB
cord-330553-sukrjl22	12	2	,	,	,
cord-330553-sukrjl22	12	3	it	-PRON-	PRP
cord-330553-sukrjl22	12	4	also	also	RB
cord-330553-sukrjl22	12	5	appears	appear	VBZ
cord-330553-sukrjl22	12	6	that	that	IN
cord-330553-sukrjl22	12	7	activated	activate	VBN
cord-330553-sukrjl22	12	8	microglia	microglia	NNS
cord-330553-sukrjl22	12	9	are	be	VBP
cord-330553-sukrjl22	12	10	triggered	trigger	VBN
cord-330553-sukrjl22	12	11	by	by	IN
cord-330553-sukrjl22	12	12	T	T	NNP
cord-330553-sukrjl22	12	13	cells	cell	NNS
cord-330553-sukrjl22	12	14	to	to	TO
cord-330553-sukrjl22	12	15	mediate	mediate	VB
cord-330553-sukrjl22	12	16	synaptic	synaptic	JJ
cord-330553-sukrjl22	12	17	elimination	elimination	NN
cord-330553-sukrjl22	12	18	at	at	IN
cord-330553-sukrjl22	12	19	late	late	JJ
cord-330553-sukrjl22	12	20	times	time	NNS
cord-330553-sukrjl22	12	21	during	during	IN
cord-330553-sukrjl22	12	22	infection	infection	NN
cord-330553-sukrjl22	12	23	,	,	,
cord-330553-sukrjl22	12	24	which	which	WDT
cord-330553-sukrjl22	12	25	may	may	MD
cord-330553-sukrjl22	12	26	contribute	contribute	VB
cord-330553-sukrjl22	12	27	to	to	IN
cord-330553-sukrjl22	12	28	long	long	JJ
cord-330553-sukrjl22	12	29	-	-	HYPH
cord-330553-sukrjl22	12	30	term	term	NN
cord-330553-sukrjl22	12	31	neurological	neurological	JJ
cord-330553-sukrjl22	12	32	deficits	deficit	NNS
cord-330553-sukrjl22	12	33	following	follow	VBG
cord-330553-sukrjl22	12	34	a	a	DT
cord-330553-sukrjl22	12	35	neuroinvasive	neuroinvasive	JJ
cord-330553-sukrjl22	12	36	WNV	WNV	NNP
cord-330553-sukrjl22	12	37	infection	infection	NN
cord-330553-sukrjl22	12	38	.	.	.
cord-330553-sukrjl22	13	1	This	this	DT
cord-330553-sukrjl22	13	2	review	review	NN
cord-330553-sukrjl22	13	3	will	will	MD
cord-330553-sukrjl22	13	4	discuss	discuss	VB
cord-330553-sukrjl22	13	5	the	the	DT
cord-330553-sukrjl22	13	6	important	important	JJ
cord-330553-sukrjl22	13	7	role	role	NN
cord-330553-sukrjl22	13	8	of	of	IN
cord-330553-sukrjl22	13	9	microglia	microglia	NNS
cord-330553-sukrjl22	13	10	in	in	IN
cord-330553-sukrjl22	13	11	the	the	DT
cord-330553-sukrjl22	13	12	pathogenesis	pathogenesis	NN
cord-330553-sukrjl22	13	13	of	of	IN
cord-330553-sukrjl22	13	14	a	a	DT
cord-330553-sukrjl22	13	15	neuroinvasive	neuroinvasive	JJ
cord-330553-sukrjl22	13	16	WNV	WNV	NNP
cord-330553-sukrjl22	13	17	infection	infection	NN
cord-330553-sukrjl22	13	18	.	.	.
cord-330553-sukrjl22	14	1	Knowledge	knowledge	NN
cord-330553-sukrjl22	14	2	of	of	IN
cord-330553-sukrjl22	14	3	the	the	DT
cord-330553-sukrjl22	14	4	precise	precise	JJ
cord-330553-sukrjl22	14	5	role	role	NN
cord-330553-sukrjl22	14	6	of	of	IN
cord-330553-sukrjl22	14	7	microglia	microglia	NNP
cord-330553-sukrjl22	14	8	during	during	IN
cord-330553-sukrjl22	14	9	a	a	DT
cord-330553-sukrjl22	14	10	WNV	WNV	NNP
cord-330553-sukrjl22	14	11	infection	infection	NN
cord-330553-sukrjl22	14	12	may	may	MD
cord-330553-sukrjl22	14	13	lead	lead	VB
cord-330553-sukrjl22	14	14	to	to	IN
cord-330553-sukrjl22	14	15	a	a	DT
cord-330553-sukrjl22	14	16	greater	great	JJR
cord-330553-sukrjl22	14	17	ability	ability	NN
cord-330553-sukrjl22	14	18	to	to	TO
cord-330553-sukrjl22	14	19	treat	treat	VB
cord-330553-sukrjl22	14	20	and	and	CC
cord-330553-sukrjl22	14	21	manage	manage	VB
cord-330553-sukrjl22	14	22	WNV	WNV	NNP
cord-330553-sukrjl22	14	23	encephalitis	encephalitis	RB
cord-330553-sukrjl22	14	24	.	.	.
cord-330553-sukrjl22	15	1	West	West	NNP
cord-330553-sukrjl22	15	2	Nile	Nile	NNP
cord-330553-sukrjl22	15	3	Virus	Virus	NNP
cord-330553-sukrjl22	15	4	(	(	-LRB-
cord-330553-sukrjl22	15	5	WNV	WNV	NNP
cord-330553-sukrjl22	15	6	)	)	-RRB-
cord-330553-sukrjl22	15	7	is	be	VBZ
cord-330553-sukrjl22	15	8	a	a	DT
cord-330553-sukrjl22	15	9	neurotropic	neurotropic	NNP
cord-330553-sukrjl22	15	10	,	,	,
cord-330553-sukrjl22	15	11	mosquito	mosquito	NN
cord-330553-sukrjl22	15	12	-	-	HYPH
cord-330553-sukrjl22	15	13	borne	bear	VBN
cord-330553-sukrjl22	15	14	,	,	,
cord-330553-sukrjl22	15	15	single	single	RB
cord-330553-sukrjl22	15	16	-	-	HYPH
cord-330553-sukrjl22	15	17	stranded	strand	VBN
cord-330553-sukrjl22	15	18	RNA	RNA	NNP
cord-330553-sukrjl22	15	19	flavivirus	flavivirus	NNP
cord-330553-sukrjl22	15	20	maintained	maintain	VBD
cord-330553-sukrjl22	15	21	in	in	IN
cord-330553-sukrjl22	15	22	an	an	DT
cord-330553-sukrjl22	15	23	enzootic	enzootic	JJ
cord-330553-sukrjl22	15	24	cycle	cycle	NN
cord-330553-sukrjl22	15	25	between	between	IN
cord-330553-sukrjl22	15	26	mosquitos	mosquitos	NN
cord-330553-sukrjl22	15	27	,	,	,
cord-330553-sukrjl22	15	28	such	such	JJ
cord-330553-sukrjl22	15	29	as	as	IN
cord-330553-sukrjl22	15	30	Culex	Culex	NNP
cord-330553-sukrjl22	15	31	pipiens	pipien	NNS
cord-330553-sukrjl22	15	32	,	,	,
cord-330553-sukrjl22	15	33	and	and	CC
cord-330553-sukrjl22	15	34	perching	perch	VBG
cord-330553-sukrjl22	15	35	birds	bird	NNS
cord-330553-sukrjl22	15	36	(	(	-LRB-
cord-330553-sukrjl22	15	37	order	order	NN
cord-330553-sukrjl22	15	38	Passeriformes	Passeriformes	NNP
cord-330553-sukrjl22	15	39	)	)	-RRB-
cord-330553-sukrjl22	15	40	,	,	,
cord-330553-sukrjl22	15	41	such	such	JJ
cord-330553-sukrjl22	15	42	as	as	IN
cord-330553-sukrjl22	15	43	crows	crow	NNS
cord-330553-sukrjl22	15	44	,	,	,
cord-330553-sukrjl22	15	45	jays	jay	NNS
cord-330553-sukrjl22	15	46	,	,	,
cord-330553-sukrjl22	15	47	and	and	CC
cord-330553-sukrjl22	15	48	finches	finch	NNS
cord-330553-sukrjl22	15	49	[	[	-LRB-
cord-330553-sukrjl22	15	50	1	1	CD
cord-330553-sukrjl22	15	51	,	,	,
cord-330553-sukrjl22	15	52	2	2	CD
cord-330553-sukrjl22	15	53	]	]	-RRB-
cord-330553-sukrjl22	15	54	.	.	.
cord-330553-sukrjl22	16	1	While	while	IN
cord-330553-sukrjl22	16	2	birds	bird	NNS
cord-330553-sukrjl22	16	3	are	be	VBP
cord-330553-sukrjl22	16	4	the	the	DT
cord-330553-sukrjl22	16	5	natural	natural	JJ
cord-330553-sukrjl22	16	6	reservoir	reservoir	NN
cord-330553-sukrjl22	16	7	for	for	IN
cord-330553-sukrjl22	16	8	WNV	WNV	NNP
cord-330553-sukrjl22	16	9	,	,	,
cord-330553-sukrjl22	16	10	an	an	DT
cord-330553-sukrjl22	16	11	infected	infected	JJ
cord-330553-sukrjl22	16	12	mosquito	mosquito	NN
cord-330553-sukrjl22	16	13	may	may	MD
cord-330553-sukrjl22	16	14	bite	bite	VB
cord-330553-sukrjl22	16	15	other	other	JJ
cord-330553-sukrjl22	16	16	mammals	mammal	NNS
cord-330553-sukrjl22	16	17	such	such	JJ
cord-330553-sukrjl22	16	18	as	as	IN
cord-330553-sukrjl22	16	19	horses	horse	NNS
cord-330553-sukrjl22	16	20	and	and	CC
cord-330553-sukrjl22	16	21	humans	human	NNS
cord-330553-sukrjl22	16	22	and	and	CC
cord-330553-sukrjl22	16	23	transmit	transmit	VB
cord-330553-sukrjl22	16	24	the	the	DT
cord-330553-sukrjl22	16	25	virus	virus	NN
cord-330553-sukrjl22	16	26	through	through	IN
cord-330553-sukrjl22	16	27	saliva	saliva	NN
cord-330553-sukrjl22	16	28	[	[	-LRB-
cord-330553-sukrjl22	16	29	2	2	CD
cord-330553-sukrjl22	16	30	]	]	-RRB-
cord-330553-sukrjl22	16	31	.	.	.
cord-330553-sukrjl22	17	1	After	after	IN
cord-330553-sukrjl22	17	2	an	an	DT
cord-330553-sukrjl22	17	3	infected	infected	JJ
cord-330553-sukrjl22	17	4	mosquito	mosquito	NN
cord-330553-sukrjl22	17	5	bites	bite	NNS
cord-330553-sukrjl22	17	6	a	a	DT
cord-330553-sukrjl22	17	7	human	human	NN
cord-330553-sukrjl22	17	8	,	,	,
cord-330553-sukrjl22	17	9	the	the	DT
cord-330553-sukrjl22	17	10	virus	virus	NN
cord-330553-sukrjl22	17	11	replicates	replicate	VBZ
cord-330553-sukrjl22	17	12	within	within	IN
cord-330553-sukrjl22	17	13	dendritic	dendritic	JJ
cord-330553-sukrjl22	17	14	cells	cell	NNS
cord-330553-sukrjl22	17	15	and	and	CC
cord-330553-sukrjl22	17	16	macrophages	macrophage	NNS
cord-330553-sukrjl22	17	17	of	of	IN
cord-330553-sukrjl22	17	18	local	local	JJ
cord-330553-sukrjl22	17	19	tissue	tissue	NN
cord-330553-sukrjl22	17	20	near	near	IN
cord-330553-sukrjl22	17	21	the	the	DT
cord-330553-sukrjl22	17	22	site	site	NN
cord-330553-sukrjl22	17	23	of	of	IN
cord-330553-sukrjl22	17	24	inoculation	inoculation	NN
cord-330553-sukrjl22	17	25	and	and	CC
cord-330553-sukrjl22	17	26	subsequently	subsequently	RB
cord-330553-sukrjl22	17	27	spreads	spread	VBZ
cord-330553-sukrjl22	17	28	to	to	IN
cord-330553-sukrjl22	17	29	regional	regional	JJ
cord-330553-sukrjl22	17	30	lymph	lymph	NN
cord-330553-sukrjl22	17	31	nodes	node	NNS
cord-330553-sukrjl22	17	32	.	.	.
cord-330553-sukrjl22	18	1	The	the	DT
cord-330553-sukrjl22	18	2	resulting	result	VBG
cord-330553-sukrjl22	18	3	viremia	viremia	NN
cord-330553-sukrjl22	18	4	then	then	RB
cord-330553-sukrjl22	18	5	spreads	spread	VBZ
cord-330553-sukrjl22	18	6	the	the	DT
cord-330553-sukrjl22	18	7	virus	virus	NN
cord-330553-sukrjl22	18	8	throughout	throughout	IN
cord-330553-sukrjl22	18	9	the	the	DT
cord-330553-sukrjl22	18	10	body	body	NN
cord-330553-sukrjl22	18	11	[	[	-LRB-
cord-330553-sukrjl22	18	12	2	2	CD
cord-330553-sukrjl22	18	13	]	]	-RRB-
cord-330553-sukrjl22	18	14	.	.	.
cord-330553-sukrjl22	19	1	West	West	NNP
cord-330553-sukrjl22	19	2	Nile	Nile	NNP
cord-330553-sukrjl22	19	3	Virus	Virus	NNP
cord-330553-sukrjl22	19	4	viremia	viremia	NN
cord-330553-sukrjl22	19	5	in	in	IN
cord-330553-sukrjl22	19	6	humans	human	NNS
cord-330553-sukrjl22	19	7	is	be	VBZ
cord-330553-sukrjl22	19	8	not	not	RB
cord-330553-sukrjl22	19	9	high	high	JJ
cord-330553-sukrjl22	19	10	enough	enough	RB
cord-330553-sukrjl22	19	11	or	or	CC
cord-330553-sukrjl22	19	12	sustained	sustain	VBN
cord-330553-sukrjl22	19	13	enough	enough	RB
cord-330553-sukrjl22	19	14	to	to	TO
cord-330553-sukrjl22	19	15	support	support	VB
cord-330553-sukrjl22	19	16	subsequent	subsequent	JJ
cord-330553-sukrjl22	19	17	transmission	transmission	NN
cord-330553-sukrjl22	19	18	to	to	IN
cord-330553-sukrjl22	19	19	mosquitoes	mosquito	NNS
cord-330553-sukrjl22	19	20	,	,	,
cord-330553-sukrjl22	19	21	thus	thus	RB
cord-330553-sukrjl22	19	22	humans	human	NNS
cord-330553-sukrjl22	19	23	are	be	VBP
cord-330553-sukrjl22	19	24	designated	designate	VBN
cord-330553-sukrjl22	19	25	"	"	``
cord-330553-sukrjl22	19	26	dead	dead	JJ
cord-330553-sukrjl22	19	27	-	-	HYPH
cord-330553-sukrjl22	19	28	end	end	NN
cord-330553-sukrjl22	19	29	"	"	''
cord-330553-sukrjl22	19	30	hosts	host	NNS
cord-330553-sukrjl22	19	31	[	[	-LRB-
cord-330553-sukrjl22	19	32	1	1	CD
cord-330553-sukrjl22	19	33	,	,	,
cord-330553-sukrjl22	19	34	2	2	CD
cord-330553-sukrjl22	19	35	]	]	-RRB-
cord-330553-sukrjl22	19	36	.	.	.
cord-330553-sukrjl22	20	1	West	West	NNP
cord-330553-sukrjl22	20	2	Nile	Nile	NNP
cord-330553-sukrjl22	20	3	Virus	Virus	NNP
cord-330553-sukrjl22	20	4	infection	infection	NN
cord-330553-sukrjl22	20	5	is	be	VBZ
cord-330553-sukrjl22	20	6	now	now	RB
cord-330553-sukrjl22	20	7	the	the	DT
cord-330553-sukrjl22	20	8	most	most	RBS
cord-330553-sukrjl22	20	9	common	common	JJ
cord-330553-sukrjl22	20	10	cause	cause	NN
cord-330553-sukrjl22	20	11	of	of	IN
cord-330553-sukrjl22	20	12	epidemic	epidemic	NN
cord-330553-sukrjl22	20	13	viral	viral	JJ
cord-330553-sukrjl22	20	14	encephalitis	encephalitis	RB
cord-330553-sukrjl22	20	15	in	in	IN
cord-330553-sukrjl22	20	16	the	the	DT
cord-330553-sukrjl22	20	17	United	United	NNP
cord-330553-sukrjl22	20	18	States	States	NNP
cord-330553-sukrjl22	20	19	.	.	.
cord-330553-sukrjl22	21	1	According	accord	VBG
cord-330553-sukrjl22	21	2	to	to	IN
cord-330553-sukrjl22	21	3	the	the	DT
cord-330553-sukrjl22	21	4	Center	Center	NNP
cord-330553-sukrjl22	21	5	for	for	IN
cord-330553-sukrjl22	21	6	Disease	Disease	NNP
cord-330553-sukrjl22	21	7	Control	Control	NNP
cord-330553-sukrjl22	21	8	(	(	-LRB-
cord-330553-sukrjl22	21	9	CDC	CDC	NNP
cord-330553-sukrjl22	21	10	)	)	-RRB-
cord-330553-sukrjl22	21	11	,	,	,
cord-330553-sukrjl22	21	12	since	since	IN
cord-330553-sukrjl22	21	13	its	-PRON-	PRP$
cord-330553-sukrjl22	21	14	introduction	introduction	NN
cord-330553-sukrjl22	21	15	into	into	IN
cord-330553-sukrjl22	21	16	North	North	NNP
cord-330553-sukrjl22	21	17	West	West	NNP
cord-330553-sukrjl22	21	18	Nile	Nile	NNP
cord-330553-sukrjl22	21	19	Virus	Virus	NNP
cord-330553-sukrjl22	21	20	-	-	HYPH
cord-330553-sukrjl22	21	21	induced	induce	VBN
cord-330553-sukrjl22	21	22	CNS	CNS	NNP
cord-330553-sukrjl22	21	23	disease	disease	NN
cord-330553-sukrjl22	21	24	occurs	occur	VBZ
cord-330553-sukrjl22	21	25	as	as	IN
cord-330553-sukrjl22	21	26	a	a	DT
cord-330553-sukrjl22	21	27	result	result	NN
cord-330553-sukrjl22	21	28	of	of	IN
cord-330553-sukrjl22	21	29	virus	virus	NN
cord-330553-sukrjl22	21	30	crossing	cross	VBG
cord-330553-sukrjl22	21	31	the	the	DT
cord-330553-sukrjl22	21	32	blood	blood	NN
cord-330553-sukrjl22	21	33	brain	brain	NN
cord-330553-sukrjl22	21	34	barrier	barrier	NN
cord-330553-sukrjl22	21	35	(	(	-LRB-
cord-330553-sukrjl22	21	36	BBB	BBB	NNP
cord-330553-sukrjl22	21	37	)	)	-RRB-
cord-330553-sukrjl22	21	38	following	follow	VBG
cord-330553-sukrjl22	21	39	systemic	systemic	JJ
cord-330553-sukrjl22	21	40	infection	infection	NN
cord-330553-sukrjl22	21	41	.	.	.
cord-330553-sukrjl22	22	1	Mechanisms	mechanism	NNS
cord-330553-sukrjl22	22	2	of	of	IN
cord-330553-sukrjl22	22	3	viral	viral	JJ
cord-330553-sukrjl22	22	4	entry	entry	NN
cord-330553-sukrjl22	22	5	into	into	IN
cord-330553-sukrjl22	22	6	the	the	DT
cord-330553-sukrjl22	22	7	CNS	CNS	NNP
cord-330553-sukrjl22	22	8	are	be	VBP
cord-330553-sukrjl22	22	9	not	not	RB
cord-330553-sukrjl22	22	10	yet	yet	RB
cord-330553-sukrjl22	22	11	fully	fully	RB
cord-330553-sukrjl22	22	12	understood	understand	VBN
cord-330553-sukrjl22	22	13	.	.	.
cord-330553-sukrjl22	23	1	However	however	RB
cord-330553-sukrjl22	23	2	,	,	,
cord-330553-sukrjl22	23	3	theories	theory	NNS
cord-330553-sukrjl22	23	4	include	include	VBP
cord-330553-sukrjl22	23	5	a	a	DT
cord-330553-sukrjl22	23	6	cytokine	cytokine	NN
cord-330553-sukrjl22	23	7	-	-	HYPH
cord-330553-sukrjl22	23	8	mediated	mediate	VBN
cord-330553-sukrjl22	23	9	increase	increase	NN
cord-330553-sukrjl22	23	10	in	in	IN
cord-330553-sukrjl22	23	11	permeability	permeability	NN
cord-330553-sukrjl22	23	12	of	of	IN
cord-330553-sukrjl22	23	13	the	the	DT
cord-330553-sukrjl22	23	14	BBB	BBB	NNP
cord-330553-sukrjl22	23	15	,	,	,
cord-330553-sukrjl22	23	16	hematogenous	hematogenous	JJ
cord-330553-sukrjl22	23	17	entry	entry	NN
cord-330553-sukrjl22	23	18	by	by	IN
cord-330553-sukrjl22	23	19	infection	infection	NN
cord-330553-sukrjl22	23	20	of	of	IN
cord-330553-sukrjl22	23	21	infiltrating	infiltrate	VBG
cord-330553-sukrjl22	23	22	immune	immune	JJ
cord-330553-sukrjl22	23	23	cells	cell	NNS
cord-330553-sukrjl22	23	24	,	,	,
cord-330553-sukrjl22	23	25	and	and	CC
cord-330553-sukrjl22	23	26	retrograde	retrograde	JJ
cord-330553-sukrjl22	23	27	axonal	axonal	JJ
cord-330553-sukrjl22	23	28	transport	transport	NN
cord-330553-sukrjl22	23	29	[	[	-LRB-
cord-330553-sukrjl22	23	30	7	7	CD
cord-330553-sukrjl22	23	31	,	,	,
cord-330553-sukrjl22	23	32	16	16	CD
cord-330553-sukrjl22	23	33	,	,	,
cord-330553-sukrjl22	23	34	17	17	CD
cord-330553-sukrjl22	23	35	]	]	-RRB-
cord-330553-sukrjl22	23	36	.	.	.
cord-330553-sukrjl22	24	1	The	the	DT
cord-330553-sukrjl22	24	2	greatest	great	JJS
cord-330553-sukrjl22	24	3	risk	risk	NN
cord-330553-sukrjl22	24	4	factor	factor	NN
cord-330553-sukrjl22	24	5	for	for	IN
cord-330553-sukrjl22	24	6	developing	develop	VBG
cord-330553-sukrjl22	24	7	WNV	WNV	NNP
cord-330553-sukrjl22	24	8	neuroinvasive	neuroinvasive	JJ
cord-330553-sukrjl22	24	9	disease	disease	NN
cord-330553-sukrjl22	24	10	is	be	VBZ
cord-330553-sukrjl22	24	11	older	old	JJR
cord-330553-sukrjl22	24	12	age	age	NN
cord-330553-sukrjl22	24	13	(	(	-LRB-
cord-330553-sukrjl22	24	14	>	>	NFP
cord-330553-sukrjl22	24	15	64	64	CD
cord-330553-sukrjl22	24	16	years	year	NNS
cord-330553-sukrjl22	24	17	)	)	-RRB-
cord-330553-sukrjl22	24	18	,	,	,
cord-330553-sukrjl22	24	19	while	while	IN
cord-330553-sukrjl22	24	20	other	other	JJ
cord-330553-sukrjl22	24	21	risk	risk	NN
cord-330553-sukrjl22	24	22	factors	factor	NNS
cord-330553-sukrjl22	24	23	include	include	VBP
cord-330553-sukrjl22	24	24	hypertension	hypertension	NN
cord-330553-sukrjl22	24	25	and	and	CC
cord-330553-sukrjl22	24	26	diabetes	diabetes	NN
cord-330553-sukrjl22	24	27	[	[	-LRB-
cord-330553-sukrjl22	24	28	18	18	CD
cord-330553-sukrjl22	24	29	]	]	-RRB-
cord-330553-sukrjl22	24	30	.	.	.
cord-330553-sukrjl22	25	1	Certain	certain	JJ
cord-330553-sukrjl22	25	2	genetic	genetic	JJ
cord-330553-sukrjl22	25	3	factors	factor	NNS
cord-330553-sukrjl22	25	4	also	also	RB
cord-330553-sukrjl22	25	5	dictate	dictate	VBP
cord-330553-sukrjl22	25	6	increased	increase	VBN
cord-330553-sukrjl22	25	7	susceptibility	susceptibility	NN
cord-330553-sukrjl22	25	8	to	to	IN
cord-330553-sukrjl22	25	9	neuroinvasive	neuroinvasive	JJ
cord-330553-sukrjl22	25	10	disease	disease	NN
cord-330553-sukrjl22	25	11	including	include	VBG
cord-330553-sukrjl22	25	12	single	single	JJ
cord-330553-sukrjl22	25	13	nucleotide	nucleotide	JJ
cord-330553-sukrjl22	25	14	polymorphisms	polymorphism	NNS
cord-330553-sukrjl22	25	15	in	in	IN
cord-330553-sukrjl22	25	16	the	the	DT
cord-330553-sukrjl22	25	17	oligoadenylate	oligoadenylate	JJ
cord-330553-sukrjl22	25	18	synthetase	synthetase	NN
cord-330553-sukrjl22	25	19	(	(	-LRB-
cord-330553-sukrjl22	25	20	OAS	OAS	NNP
cord-330553-sukrjl22	25	21	)	)	-RRB-
cord-330553-sukrjl22	25	22	gene	gene	NN
cord-330553-sukrjl22	25	23	(	(	-LRB-
cord-330553-sukrjl22	25	24	involved	involve	VBN
cord-330553-sukrjl22	25	25	in	in	IN
cord-330553-sukrjl22	25	26	antiviral	antiviral	JJ
cord-330553-sukrjl22	25	27	innate	innate	JJ
cord-330553-sukrjl22	25	28	immunity	immunity	NN
cord-330553-sukrjl22	25	29	)	)	-RRB-
cord-330553-sukrjl22	25	30	and	and	CC
cord-330553-sukrjl22	25	31	genetic	genetic	JJ
cord-330553-sukrjl22	25	32	deficiencies	deficiency	NNS
cord-330553-sukrjl22	25	33	in	in	IN
cord-330553-sukrjl22	25	34	C	C	NNP
cord-330553-sukrjl22	25	35	-	-	HYPH
cord-330553-sukrjl22	25	36	C	C	NNP
cord-330553-sukrjl22	25	37	chemokine	chemokine	NN
cord-330553-sukrjl22	25	38	receptor	receptor	NN
cord-330553-sukrjl22	25	39	type	type	NN
cord-330553-sukrjl22	25	40	5	5	CD
cord-330553-sukrjl22	25	41	(	(	-LRB-
cord-330553-sukrjl22	25	42	CCR5	CCR5	NNP
cord-330553-sukrjl22	25	43	)	)	-RRB-
cord-330553-sukrjl22	25	44	,	,	,
cord-330553-sukrjl22	25	45	which	which	WDT
cord-330553-sukrjl22	25	46	inhibit	inhibit	VBP
cord-330553-sukrjl22	25	47	lymphocyte	lymphocyte	NN
cord-330553-sukrjl22	25	48	trafficking	trafficking	NN
cord-330553-sukrjl22	25	49	into	into	IN
cord-330553-sukrjl22	25	50	the	the	DT
cord-330553-sukrjl22	25	51	CNS	CNS	NNP
cord-330553-sukrjl22	25	52	[	[	-LRB-
cord-330553-sukrjl22	25	53	19	19	CD
cord-330553-sukrjl22	25	54	,	,	,
cord-330553-sukrjl22	25	55	20	20	CD
cord-330553-sukrjl22	25	56	]	]	-RRB-
cord-330553-sukrjl22	25	57	.	.	.
cord-330553-sukrjl22	26	1	Once	once	RB
cord-330553-sukrjl22	26	2	within	within	IN
cord-330553-sukrjl22	26	3	the	the	DT
cord-330553-sukrjl22	26	4	CNS	CNS	NNP
cord-330553-sukrjl22	26	5	,	,	,
cord-330553-sukrjl22	26	6	WNV	WNV	NNP
cord-330553-sukrjl22	26	7	directly	directly	RB
cord-330553-sukrjl22	26	8	infects	infect	VBZ
cord-330553-sukrjl22	26	9	neurons	neuron	NNS
cord-330553-sukrjl22	26	10	and	and	CC
cord-330553-sukrjl22	26	11	several	several	JJ
cord-330553-sukrjl22	26	12	studies	study	NNS
cord-330553-sukrjl22	26	13	demonstrate	demonstrate	VBP
cord-330553-sukrjl22	26	14	that	that	IN
cord-330553-sukrjl22	26	15	caspase	caspase	NN
cord-330553-sukrjl22	26	16	3-dependent	3-dependent	CD
cord-330553-sukrjl22	26	17	apoptosis	apoptosis	NN
cord-330553-sukrjl22	26	18	is	be	VBZ
cord-330553-sukrjl22	26	19	an	an	DT
cord-330553-sukrjl22	26	20	important	important	JJ
cord-330553-sukrjl22	26	21	mechanism	mechanism	NN
cord-330553-sukrjl22	26	22	of	of	IN
cord-330553-sukrjl22	26	23	neuronal	neuronal	JJ
cord-330553-sukrjl22	26	24	cell	cell	NN
cord-330553-sukrjl22	26	25	death	death	NN
cord-330553-sukrjl22	26	26	and	and	CC
cord-330553-sukrjl22	26	27	CNS	CNS	NNP
cord-330553-sukrjl22	26	28	injury	injury	NN
cord-330553-sukrjl22	26	29	during	during	IN
cord-330553-sukrjl22	26	30	WNV	WNV	NNP
cord-330553-sukrjl22	26	31	infection	infection	NN
cord-330553-sukrjl22	26	32	[	[	-LRB-
cord-330553-sukrjl22	26	33	21	21	CD
cord-330553-sukrjl22	26	34	,	,	,
cord-330553-sukrjl22	26	35	22	22	CD
cord-330553-sukrjl22	26	36	]	]	-RRB-
cord-330553-sukrjl22	26	37	.	.	.
cord-330553-sukrjl22	27	1	The	the	DT
cord-330553-sukrjl22	27	2	pathology	pathology	NN
cord-330553-sukrjl22	27	3	of	of	IN
cord-330553-sukrjl22	27	4	neuroinvasive	neuroinvasive	JJ
cord-330553-sukrjl22	27	5	WNV	WNV	NNP
cord-330553-sukrjl22	27	6	infection	infection	NN
cord-330553-sukrjl22	27	7	likely	likely	JJ
cord-330553-sukrjl22	27	8	results	result	VBZ
cord-330553-sukrjl22	27	9	from	from	IN
cord-330553-sukrjl22	27	10	both	both	DT
cord-330553-sukrjl22	27	11	apoptosis	apoptosis	NN
cord-330553-sukrjl22	27	12	of	of	IN
cord-330553-sukrjl22	27	13	neurons	neuron	NNS
cord-330553-sukrjl22	27	14	and	and	CC
cord-330553-sukrjl22	27	15	secondary	secondary	JJ
cord-330553-sukrjl22	27	16	effects	effect	NNS
cord-330553-sukrjl22	27	17	of	of	IN
cord-330553-sukrjl22	27	18	the	the	DT
cord-330553-sukrjl22	27	19	neuroinflammatory	neuroinflammatory	NNP
cord-330553-sukrjl22	27	20	response	response	NN
cord-330553-sukrjl22	27	21	,	,	,
cord-330553-sukrjl22	27	22	including	include	VBG
cord-330553-sukrjl22	27	23	damage	damage	NN
cord-330553-sukrjl22	27	24	to	to	IN
cord-330553-sukrjl22	27	25	bystander	bystander	NN
cord-330553-sukrjl22	27	26	cells	cell	NNS
cord-330553-sukrjl22	27	27	and	and	CC
cord-330553-sukrjl22	27	28	gliosis	gliosis	NNP
cord-330553-sukrjl22	27	29	[	[	-LRB-
cord-330553-sukrjl22	27	30	22	22	CD
cord-330553-sukrjl22	27	31	]	]	-RRB-
cord-330553-sukrjl22	27	32	.	.	.
cord-330553-sukrjl22	28	1	A	a	DT
cord-330553-sukrjl22	28	2	critical	critical	JJ
cord-330553-sukrjl22	28	3	component	component	NN
cord-330553-sukrjl22	28	4	of	of	IN
cord-330553-sukrjl22	28	5	the	the	DT
cord-330553-sukrjl22	28	6	neuroinflammatory	neuroinflammatory	NNP
cord-330553-sukrjl22	28	7	response	response	NN
cord-330553-sukrjl22	28	8	induced	induce	VBN
cord-330553-sukrjl22	28	9	by	by	IN
cord-330553-sukrjl22	28	10	WNV	WNV	NNP
cord-330553-sukrjl22	28	11	infection	infection	NN
cord-330553-sukrjl22	28	12	is	be	VBZ
cord-330553-sukrjl22	28	13	the	the	DT
cord-330553-sukrjl22	28	14	activation	activation	NN
cord-330553-sukrjl22	28	15	of	of	IN
cord-330553-sukrjl22	28	16	microglia	microglia	NNP
cord-330553-sukrjl22	28	17	,	,	,
cord-330553-sukrjl22	28	18	the	the	DT
cord-330553-sukrjl22	28	19	innate	innate	JJ
cord-330553-sukrjl22	28	20	immune	immune	JJ
cord-330553-sukrjl22	28	21	cells	cell	NNS
cord-330553-sukrjl22	28	22	of	of	IN
cord-330553-sukrjl22	28	23	the	the	DT
cord-330553-sukrjl22	28	24	CNS	CNS	NNP
cord-330553-sukrjl22	28	25	[	[	-LRB-
cord-330553-sukrjl22	28	26	23	23	CD
cord-330553-sukrjl22	28	27	]	]	-RRB-
cord-330553-sukrjl22	28	28	.	.	.
cord-330553-sukrjl22	29	1	In	in	IN
cord-330553-sukrjl22	29	2	this	this	DT
cord-330553-sukrjl22	29	3	review	review	NN
cord-330553-sukrjl22	29	4	,	,	,
cord-330553-sukrjl22	29	5	we	-PRON-	PRP
cord-330553-sukrjl22	29	6	will	will	MD
cord-330553-sukrjl22	29	7	discuss	discuss	VB
cord-330553-sukrjl22	29	8	the	the	DT
cord-330553-sukrjl22	29	9	role	role	NN
cord-330553-sukrjl22	29	10	of	of	IN
cord-330553-sukrjl22	29	11	microglia	microglia	NN
cord-330553-sukrjl22	29	12	in	in	IN
cord-330553-sukrjl22	29	13	WNV	WNV	NNP
cord-330553-sukrjl22	29	14	-	-	HYPH
cord-330553-sukrjl22	29	15	induced	induce	VBN
cord-330553-sukrjl22	29	16	CNS	CNS	NNP
cord-330553-sukrjl22	29	17	disease	disease	NN
cord-330553-sukrjl22	29	18	as	as	IN
cord-330553-sukrjl22	29	19	a	a	DT
cord-330553-sukrjl22	29	20	contributor	contributor	NN
cord-330553-sukrjl22	29	21	both	both	DT
cord-330553-sukrjl22	29	22	to	to	IN
cord-330553-sukrjl22	29	23	the	the	DT
cord-330553-sukrjl22	29	24	protective	protective	JJ
cord-330553-sukrjl22	29	25	innate	innate	JJ
cord-330553-sukrjl22	29	26	immune	immune	JJ
cord-330553-sukrjl22	29	27	response	response	NN
cord-330553-sukrjl22	29	28	and	and	CC
cord-330553-sukrjl22	29	29	to	to	IN
cord-330553-sukrjl22	29	30	the	the	DT
cord-330553-sukrjl22	29	31	development	development	NN
cord-330553-sukrjl22	29	32	of	of	IN
cord-330553-sukrjl22	29	33	long	long	JJ
cord-330553-sukrjl22	29	34	-	-	HYPH
cord-330553-sukrjl22	29	35	term	term	NN
cord-330553-sukrjl22	29	36	neurological	neurological	JJ
cord-330553-sukrjl22	29	37	damage	damage	NN
cord-330553-sukrjl22	29	38	.	.	.
cord-330553-sukrjl22	30	1	Microglia	Microglia	NNP
cord-330553-sukrjl22	30	2	are	be	VBP
cord-330553-sukrjl22	30	3	of	of	IN
cord-330553-sukrjl22	30	4	myeloid	myeloid	JJ
cord-330553-sukrjl22	30	5	origin	origin	NN
cord-330553-sukrjl22	30	6	and	and	CC
cord-330553-sukrjl22	30	7	arise	arise	VB
cord-330553-sukrjl22	30	8	from	from	IN
cord-330553-sukrjl22	30	9	the	the	DT
cord-330553-sukrjl22	30	10	yolk	yolk	NN
cord-330553-sukrjl22	30	11	sac	sac	NN
cord-330553-sukrjl22	30	12	during	during	IN
cord-330553-sukrjl22	30	13	early	early	JJ
cord-330553-sukrjl22	30	14	development	development	NN
cord-330553-sukrjl22	30	15	[	[	-LRB-
cord-330553-sukrjl22	30	16	24	24	CD
cord-330553-sukrjl22	30	17	]	]	-RRB-
cord-330553-sukrjl22	30	18	[	[	-LRB-
cord-330553-sukrjl22	30	19	25	25	CD
cord-330553-sukrjl22	30	20	]	]	-RRB-
cord-330553-sukrjl22	30	21	[	[	-LRB-
cord-330553-sukrjl22	30	22	26	26	CD
cord-330553-sukrjl22	30	23	]	]	-RRB-
cord-330553-sukrjl22	30	24	.	.	.
cord-330553-sukrjl22	31	1	These	these	DT
cord-330553-sukrjl22	31	2	cells	cell	NNS
cord-330553-sukrjl22	31	3	are	be	VBP
cord-330553-sukrjl22	31	4	the	the	DT
cord-330553-sukrjl22	31	5	resident	resident	JJ
cord-330553-sukrjl22	31	6	mononuclear	mononuclear	JJ
cord-330553-sukrjl22	31	7	phagocytic	phagocytic	JJ
cord-330553-sukrjl22	31	8	cells	cell	NNS
cord-330553-sukrjl22	31	9	of	of	IN
cord-330553-sukrjl22	31	10	the	the	DT
cord-330553-sukrjl22	31	11	CNS	CNS	NNP
cord-330553-sukrjl22	31	12	and	and	CC
cord-330553-sukrjl22	31	13	play	play	VB
cord-330553-sukrjl22	31	14	multiple	multiple	JJ
cord-330553-sukrjl22	31	15	roles	role	NNS
cord-330553-sukrjl22	31	16	in	in	IN
cord-330553-sukrjl22	31	17	the	the	DT
cord-330553-sukrjl22	31	18	CNS	CNS	NNP
cord-330553-sukrjl22	31	19	such	such	JJ
cord-330553-sukrjl22	31	20	as	as	IN
cord-330553-sukrjl22	31	21	immune	immune	JJ
cord-330553-sukrjl22	31	22	defense	defense	NN
cord-330553-sukrjl22	31	23	,	,	,
cord-330553-sukrjl22	31	24	maintenance	maintenance	NN
cord-330553-sukrjl22	31	25	of	of	IN
cord-330553-sukrjl22	31	26	homeostasis	homeostasis	NN
cord-330553-sukrjl22	31	27	,	,	,
cord-330553-sukrjl22	31	28	and	and	CC
cord-330553-sukrjl22	31	29	synaptic	synaptic	JJ
cord-330553-sukrjl22	31	30	pruning	pruning	NN
cord-330553-sukrjl22	31	31	during	during	IN
cord-330553-sukrjl22	31	32	early	early	JJ
cord-330553-sukrjl22	31	33	development	development	NN
cord-330553-sukrjl22	31	34	[	[	-LRB-
cord-330553-sukrjl22	31	35	27	27	CD
cord-330553-sukrjl22	31	36	]	]	-RRB-
cord-330553-sukrjl22	31	37	[	[	-LRB-
cord-330553-sukrjl22	31	38	28	28	CD
cord-330553-sukrjl22	31	39	]	]	-RRB-
cord-330553-sukrjl22	31	40	[	[	-LRB-
cord-330553-sukrjl22	31	41	29	29	CD
cord-330553-sukrjl22	31	42	]	]	-RRB-
cord-330553-sukrjl22	31	43	.	.	.
cord-330553-sukrjl22	32	1	Importantly	importantly	RB
cord-330553-sukrjl22	32	2	they	-PRON-	PRP
cord-330553-sukrjl22	32	3	continually	continually	RB
cord-330553-sukrjl22	32	4	monitor	monitor	VBP
cord-330553-sukrjl22	32	5	the	the	DT
cord-330553-sukrjl22	32	6	CNS	CNS	NNP
cord-330553-sukrjl22	32	7	for	for	IN
cord-330553-sukrjl22	32	8	signals	signal	NNS
cord-330553-sukrjl22	32	9	of	of	IN
cord-330553-sukrjl22	32	10	injury	injury	NN
cord-330553-sukrjl22	32	11	and	and	CC
cord-330553-sukrjl22	32	12	infection	infection	NN
cord-330553-sukrjl22	32	13	[	[	-LRB-
cord-330553-sukrjl22	32	14	28	28	CD
cord-330553-sukrjl22	32	15	,	,	,
cord-330553-sukrjl22	32	16	30	30	CD
cord-330553-sukrjl22	32	17	,	,	,
cord-330553-sukrjl22	32	18	31	31	CD
cord-330553-sukrjl22	32	19	]	]	-RRB-
cord-330553-sukrjl22	32	20	.	.	.
cord-330553-sukrjl22	33	1	Microglia	Microglia	NNP
cord-330553-sukrjl22	33	2	express	express	VBP
cord-330553-sukrjl22	33	3	a	a	DT
cord-330553-sukrjl22	33	4	spectrum	spectrum	NN
cord-330553-sukrjl22	33	5	of	of	IN
cord-330553-sukrjl22	33	6	activation	activation	NN
cord-330553-sukrjl22	33	7	states	state	NNS
cord-330553-sukrjl22	33	8	in	in	IN
cord-330553-sukrjl22	33	9	response	response	NN
cord-330553-sukrjl22	33	10	to	to	IN
cord-330553-sukrjl22	33	11	environmental	environmental	JJ
cord-330553-sukrjl22	33	12	and	and	CC
cord-330553-sukrjl22	33	13	pathogenic	pathogenic	JJ
cord-330553-sukrjl22	33	14	cues	cue	NNS
cord-330553-sukrjl22	33	15	[	[	-LRB-
cord-330553-sukrjl22	33	16	32	32	CD
cord-330553-sukrjl22	33	17	,	,	,
cord-330553-sukrjl22	33	18	33	33	CD
cord-330553-sukrjl22	33	19	]	]	-RRB-
cord-330553-sukrjl22	33	20	.	.	.
cord-330553-sukrjl22	34	1	Morphological	morphological	JJ
cord-330553-sukrjl22	34	2	changes	change	NNS
cord-330553-sukrjl22	34	3	of	of	IN
cord-330553-sukrjl22	34	4	activated	activate	VBN
cord-330553-sukrjl22	34	5	microglia	microglia	NNS
cord-330553-sukrjl22	34	6	include	include	VBP
cord-330553-sukrjl22	34	7	a	a	DT
cord-330553-sukrjl22	34	8	shift	shift	NN
cord-330553-sukrjl22	34	9	from	from	IN
cord-330553-sukrjl22	34	10	a	a	DT
cord-330553-sukrjl22	34	11	ramified	ramified	JJ
cord-330553-sukrjl22	34	12	state	state	NN
cord-330553-sukrjl22	34	13	,	,	,
cord-330553-sukrjl22	34	14	characterized	characterize	VBN
cord-330553-sukrjl22	34	15	by	by	IN
cord-330553-sukrjl22	34	16	long	long	JJ
cord-330553-sukrjl22	34	17	extending	extend	VBG
cord-330553-sukrjl22	34	18	processes	process	NNS
cord-330553-sukrjl22	34	19	,	,	,
cord-330553-sukrjl22	34	20	to	to	IN
cord-330553-sukrjl22	34	21	a	a	DT
cord-330553-sukrjl22	34	22	larger	large	JJR
cord-330553-sukrjl22	34	23	more	more	JJR
cord-330553-sukrjl22	34	24	amoeboid	amoeboid	JJ
cord-330553-sukrjl22	34	25	phenotype	phenotype	NN
cord-330553-sukrjl22	34	26	[	[	-LRB-
cord-330553-sukrjl22	34	27	34	34	CD
cord-330553-sukrjl22	34	28	]	]	-RRB-
cord-330553-sukrjl22	34	29	.	.	.
cord-330553-sukrjl22	35	1	In	in	IN
cord-330553-sukrjl22	35	2	addition	addition	NN
cord-330553-sukrjl22	35	3	,	,	,
cord-330553-sukrjl22	35	4	activated	activate	VBN
cord-330553-sukrjl22	35	5	microglia	microglia	NN
cord-330553-sukrjl22	35	6	display	display	NN
cord-330553-sukrjl22	35	7	increased	increase	VBD
cord-330553-sukrjl22	35	8	motility	motility	NN
cord-330553-sukrjl22	35	9	,	,	,
cord-330553-sukrjl22	35	10	proliferation	proliferation	NN
cord-330553-sukrjl22	35	11	and	and	CC
cord-330553-sukrjl22	35	12	production	production	NN
cord-330553-sukrjl22	35	13	of	of	IN
cord-330553-sukrjl22	35	14	inflammatory	inflammatory	JJ
cord-330553-sukrjl22	35	15	cytokines	cytokine	NNS
cord-330553-sukrjl22	35	16	and	and	CC
cord-330553-sukrjl22	35	17	chemokines	chemokine	NNS
cord-330553-sukrjl22	35	18	[	[	-LRB-
cord-330553-sukrjl22	35	19	29	29	CD
cord-330553-sukrjl22	35	20	,	,	,
cord-330553-sukrjl22	35	21	[	[	-LRB-
cord-330553-sukrjl22	35	22	35	35	CD
cord-330553-sukrjl22	35	23	]	]	-RRB-
cord-330553-sukrjl22	35	24	[	[	-LRB-
cord-330553-sukrjl22	35	25	36	36	CD
cord-330553-sukrjl22	35	26	]	]	-RRB-
cord-330553-sukrjl22	35	27	[	[	-LRB-
cord-330553-sukrjl22	35	28	37	37	CD
cord-330553-sukrjl22	35	29	]	]	-RRB-
cord-330553-sukrjl22	35	30	.	.	.
cord-330553-sukrjl22	36	1	In	in	IN
cord-330553-sukrjl22	36	2	neuroinflammatory	neuroinflammatory	JJ
cord-330553-sukrjl22	36	3	and	and	CC
cord-330553-sukrjl22	36	4	neurodegenerative	neurodegenerative	JJ
cord-330553-sukrjl22	36	5	conditions	condition	NNS
cord-330553-sukrjl22	36	6	,	,	,
cord-330553-sukrjl22	36	7	microglia	microglia	NNS
cord-330553-sukrjl22	36	8	are	be	VBP
cord-330553-sukrjl22	36	9	thought	think	VBN
cord-330553-sukrjl22	36	10	to	to	TO
cord-330553-sukrjl22	36	11	contribute	contribute	VB
cord-330553-sukrjl22	36	12	to	to	IN
cord-330553-sukrjl22	36	13	pathogenicity	pathogenicity	NN
cord-330553-sukrjl22	36	14	[	[	-LRB-
cord-330553-sukrjl22	36	15	36	36	CD
cord-330553-sukrjl22	36	16	,	,	,
cord-330553-sukrjl22	36	17	38	38	CD
cord-330553-sukrjl22	36	18	,	,	,
cord-330553-sukrjl22	36	19	39	39	CD
cord-330553-sukrjl22	36	20	]	]	-RRB-
cord-330553-sukrjl22	36	21	,	,	,
cord-330553-sukrjl22	36	22	however	however	RB
cord-330553-sukrjl22	36	23	,	,	,
cord-330553-sukrjl22	36	24	in	in	IN
cord-330553-sukrjl22	36	25	the	the	DT
cord-330553-sukrjl22	36	26	case	case	NN
cord-330553-sukrjl22	36	27	of	of	IN
cord-330553-sukrjl22	36	28	viral	viral	JJ
cord-330553-sukrjl22	36	29	encephalitis	encephalitis	RB
cord-330553-sukrjl22	36	30	,	,	,
cord-330553-sukrjl22	36	31	it	-PRON-	PRP
cord-330553-sukrjl22	36	32	remains	remain	VBZ
cord-330553-sukrjl22	36	33	unclear	unclear	JJ
cord-330553-sukrjl22	36	34	whether	whether	IN
cord-330553-sukrjl22	36	35	microglia	microglia	NNS
cord-330553-sukrjl22	36	36	are	be	VBP
cord-330553-sukrjl22	36	37	beneficial	beneficial	JJ
cord-330553-sukrjl22	36	38	or	or	CC
cord-330553-sukrjl22	36	39	detrimental	detrimental	JJ
cord-330553-sukrjl22	36	40	to	to	IN
cord-330553-sukrjl22	36	41	disease	disease	NN
cord-330553-sukrjl22	36	42	outcomes	outcome	NNS
cord-330553-sukrjl22	36	43	,	,	,
cord-330553-sukrjl22	36	44	or	or	CC
cord-330553-sukrjl22	36	45	possibly	possibly	RB
cord-330553-sukrjl22	36	46	both	both	DT
cord-330553-sukrjl22	36	47	.	.	.
cord-330553-sukrjl22	37	1	Classically	classically	RB
cord-330553-sukrjl22	37	2	,	,	,
cord-330553-sukrjl22	37	3	macrophages	macrophage	NNS
cord-330553-sukrjl22	37	4	and	and	CC
cord-330553-sukrjl22	37	5	microglia	microglia	NNS
cord-330553-sukrjl22	37	6	have	have	VBP
cord-330553-sukrjl22	37	7	been	be	VBN
cord-330553-sukrjl22	37	8	defined	define	VBN
cord-330553-sukrjl22	37	9	as	as	IN
cord-330553-sukrjl22	37	10	being	be	VBG
cord-330553-sukrjl22	37	11	polarized	polarize	VBN
cord-330553-sukrjl22	37	12	,	,	,
cord-330553-sukrjl22	37	13	meaning	mean	VBG
cord-330553-sukrjl22	37	14	they	-PRON-	PRP
cord-330553-sukrjl22	37	15	express	express	VBP
cord-330553-sukrjl22	37	16	two	two	CD
cord-330553-sukrjl22	37	17	major	major	JJ
cord-330553-sukrjl22	37	18	activation	activation	NN
cord-330553-sukrjl22	37	19	states	state	NNS
cord-330553-sukrjl22	37	20	:	:	:
cord-330553-sukrjl22	37	21	pro	pro	JJ
cord-330553-sukrjl22	37	22	-	-	JJ
cord-330553-sukrjl22	37	23	inflammatory	inflammatory	JJ
cord-330553-sukrjl22	37	24	M1	M1	NNP
cord-330553-sukrjl22	37	25	and	and	CC
cord-330553-sukrjl22	37	26	anti	anti	JJ
cord-330553-sukrjl22	37	27	-	-	JJ
cord-330553-sukrjl22	37	28	inflammatory	inflammatory	JJ
cord-330553-sukrjl22	37	29	M2	M2	NNP
cord-330553-sukrjl22	37	30	[	[	-LRB-
cord-330553-sukrjl22	37	31	40	40	CD
cord-330553-sukrjl22	37	32	]	]	-RRB-
cord-330553-sukrjl22	37	33	.	.	.
cord-330553-sukrjl22	38	1	While	while	IN
cord-330553-sukrjl22	38	2	some	some	DT
cord-330553-sukrjl22	38	3	individuals	individual	NNS
cord-330553-sukrjl22	38	4	feel	feel	VBP
cord-330553-sukrjl22	38	5	that	that	IN
cord-330553-sukrjl22	38	6	this	this	DT
cord-330553-sukrjl22	38	7	is	be	VBZ
cord-330553-sukrjl22	38	8	not	not	RB
cord-330553-sukrjl22	38	9	an	an	DT
cord-330553-sukrjl22	38	10	accurate	accurate	JJ
cord-330553-sukrjl22	38	11	description	description	NN
cord-330553-sukrjl22	38	12	of	of	IN
cord-330553-sukrjl22	38	13	microglial	microglial	JJ
cord-330553-sukrjl22	38	14	activation	activation	NN
cord-330553-sukrjl22	38	15	[	[	-LRB-
cord-330553-sukrjl22	38	16	32	32	CD
cord-330553-sukrjl22	38	17	]	]	-RRB-
cord-330553-sukrjl22	38	18	,	,	,
cord-330553-sukrjl22	38	19	it	-PRON-	PRP
cord-330553-sukrjl22	38	20	remains	remain	VBZ
cord-330553-sukrjl22	38	21	important	important	JJ
cord-330553-sukrjl22	38	22	to	to	TO
cord-330553-sukrjl22	38	23	consider	consider	VB
cord-330553-sukrjl22	38	24	the	the	DT
cord-330553-sukrjl22	38	25	role	role	NN
cord-330553-sukrjl22	38	26	of	of	IN
cord-330553-sukrjl22	38	27	microglia	microglia	JJ
cord-330553-sukrjl22	38	28	polarization	polarization	NN
cord-330553-sukrjl22	38	29	in	in	IN
cord-330553-sukrjl22	38	30	the	the	DT
cord-330553-sukrjl22	38	31	pathogenesis	pathogenesis	NN
cord-330553-sukrjl22	38	32	of	of	IN
cord-330553-sukrjl22	38	33	WNV	WNV	NNP
cord-330553-sukrjl22	38	34	infections	infection	NNS
cord-330553-sukrjl22	38	35	.	.	.
cord-330553-sukrjl22	39	1	The	the	DT
cord-330553-sukrjl22	39	2	ability	ability	NN
cord-330553-sukrjl22	39	3	to	to	TO
cord-330553-sukrjl22	39	4	shift	shift	VB
cord-330553-sukrjl22	39	5	phenotypes	phenotype	NNS
cord-330553-sukrjl22	39	6	allows	allow	VBZ
cord-330553-sukrjl22	39	7	microglia	microglia	NNS
cord-330553-sukrjl22	39	8	to	to	TO
cord-330553-sukrjl22	39	9	maintain	maintain	VB
cord-330553-sukrjl22	39	10	homeostasis	homeostasis	NN
cord-330553-sukrjl22	39	11	within	within	IN
cord-330553-sukrjl22	39	12	the	the	DT
cord-330553-sukrjl22	39	13	CNS	CNS	NNP
cord-330553-sukrjl22	39	14	.	.	.
cord-330553-sukrjl22	40	1	Following	follow	VBG
cord-330553-sukrjl22	40	2	infection	infection	NN
cord-330553-sukrjl22	40	3	of	of	IN
cord-330553-sukrjl22	40	4	the	the	DT
cord-330553-sukrjl22	40	5	CNS	CNS	NNP
cord-330553-sukrjl22	40	6	,	,	,
cord-330553-sukrjl22	40	7	microglia	microglia	NNP
cord-330553-sukrjl22	40	8	express	express	JJ
cord-330553-sukrjl22	40	9	markers	marker	NNS
cord-330553-sukrjl22	40	10	characteristic	characteristic	JJ
cord-330553-sukrjl22	40	11	of	of	IN
cord-330553-sukrjl22	40	12	M1	M1	NNP
cord-330553-sukrjl22	40	13	activation	activation	NN
cord-330553-sukrjl22	40	14	including	include	VBG
cord-330553-sukrjl22	40	15	increased	increase	VBN
cord-330553-sukrjl22	40	16	expression	expression	NN
cord-330553-sukrjl22	40	17	of	of	IN
cord-330553-sukrjl22	40	18	Iba-1	Iba-1	NNP
cord-330553-sukrjl22	40	19	,	,	,
cord-330553-sukrjl22	40	20	as	as	RB
cord-330553-sukrjl22	40	21	well	well	RB
cord-330553-sukrjl22	40	22	as	as	IN
cord-330553-sukrjl22	40	23	chemokines	chemokine	NNS
cord-330553-sukrjl22	40	24	such	such	JJ
cord-330553-sukrjl22	40	25	as	as	IN
cord-330553-sukrjl22	40	26	C	C	NNP
cord-330553-sukrjl22	40	27	-	-	HYPH
cord-330553-sukrjl22	40	28	C	C	NNP
cord-330553-sukrjl22	40	29	motif	motif	NN
cord-330553-sukrjl22	40	30	cytokine	cytokine	NN
cord-330553-sukrjl22	40	31	2	2	CD
cord-330553-sukrjl22	40	32	(	(	-LRB-
cord-330553-sukrjl22	40	33	CCL2	CCL2	NNP
cord-330553-sukrjl22	40	34	)	)	-RRB-
cord-330553-sukrjl22	40	35	,	,	,
cord-330553-sukrjl22	40	36	CCL3	CCL3	NNP
cord-330553-sukrjl22	40	37	,	,	,
cord-330553-sukrjl22	40	38	CCL5	CCL5	NNP
cord-330553-sukrjl22	40	39	,	,	,
cord-330553-sukrjl22	40	40	and	and	CC
cord-330553-sukrjl22	40	41	CCL7	CCL7	NNP
cord-330553-sukrjl22	40	42	[	[	-LRB-
cord-330553-sukrjl22	40	43	41	41	CD
cord-330553-sukrjl22	40	44	]	]	-RRB-
cord-330553-sukrjl22	40	45	.	.	.
cord-330553-sukrjl22	41	1	The	the	DT
cord-330553-sukrjl22	41	2	anti	anti	JJ
cord-330553-sukrjl22	41	3	-	-	JJ
cord-330553-sukrjl22	41	4	inflammatory	inflammatory	JJ
cord-330553-sukrjl22	41	5	drug	drug	NN
cord-330553-sukrjl22	41	6	minocycline	minocycline	NNP
cord-330553-sukrjl22	41	7	reduces	reduce	VBZ
cord-330553-sukrjl22	41	8	the	the	DT
cord-330553-sukrjl22	41	9	expression	expression	NN
cord-330553-sukrjl22	41	10	of	of	IN
cord-330553-sukrjl22	41	11	M1	M1	NNP
cord-330553-sukrjl22	41	12	inflammatory	inflammatory	JJ
cord-330553-sukrjl22	41	13	genes	gene	NNS
cord-330553-sukrjl22	41	14	and	and	CC
cord-330553-sukrjl22	41	15	increases	increase	VBZ
cord-330553-sukrjl22	41	16	the	the	DT
cord-330553-sukrjl22	41	17	expression	expression	NN
cord-330553-sukrjl22	41	18	of	of	IN
cord-330553-sukrjl22	41	19	M2	M2	NNP
cord-330553-sukrjl22	41	20	genes	gene	NNS
cord-330553-sukrjl22	41	21	,	,	,
cord-330553-sukrjl22	41	22	following	follow	VBG
cord-330553-sukrjl22	41	23	WNV	WNV	NNP
cord-330553-sukrjl22	41	24	infection	infection	NN
cord-330553-sukrjl22	41	25	of	of	IN
cord-330553-sukrjl22	41	26	CNS	CNS	NNP
cord-330553-sukrjl22	41	27	tissue	tissue	NN
cord-330553-sukrjl22	41	28	[	[	-LRB-
cord-330553-sukrjl22	41	29	42	42	CD
cord-330553-sukrjl22	41	30	]	]	-RRB-
cord-330553-sukrjl22	41	31	.	.	.
cord-330553-sukrjl22	42	1	This	this	DT
cord-330553-sukrjl22	42	2	shift	shift	NN
cord-330553-sukrjl22	42	3	of	of	IN
cord-330553-sukrjl22	42	4	microglia	microglia	NN
cord-330553-sukrjl22	42	5	towards	towards	IN
cord-330553-sukrjl22	42	6	a	a	DT
cord-330553-sukrjl22	42	7	more	more	RBR
cord-330553-sukrjl22	42	8	anti	anti	JJ
cord-330553-sukrjl22	42	9	-	-	JJ
cord-330553-sukrjl22	42	10	inflammatory	inflammatory	JJ
cord-330553-sukrjl22	42	11	M2	M2	NNP
cord-330553-sukrjl22	42	12	state	state	NN
cord-330553-sukrjl22	42	13	was	be	VBD
cord-330553-sukrjl22	42	14	neuroprotective	neuroprotective	JJ
cord-330553-sukrjl22	42	15	[	[	-LRB-
cord-330553-sukrjl22	42	16	42	42	CD
cord-330553-sukrjl22	42	17	]	]	-RRB-
cord-330553-sukrjl22	42	18	and	and	CC
cord-330553-sukrjl22	42	19	suggests	suggest	VBZ
cord-330553-sukrjl22	42	20	that	that	IN
cord-330553-sukrjl22	42	21	M1	M1	NNP
cord-330553-sukrjl22	42	22	microglia	microglia	NNS
cord-330553-sukrjl22	42	23	are	be	VBP
cord-330553-sukrjl22	42	24	required	require	VBN
cord-330553-sukrjl22	42	25	for	for	IN
cord-330553-sukrjl22	42	26	initial	initial	JJ
cord-330553-sukrjl22	42	27	control	control	NN
cord-330553-sukrjl22	42	28	of	of	IN
cord-330553-sukrjl22	42	29	WNV	WNV	NNP
cord-330553-sukrjl22	42	30	infection	infection	NN
cord-330553-sukrjl22	42	31	;	;	:
cord-330553-sukrjl22	42	32	however	however	RB
cord-330553-sukrjl22	42	33	,	,	,
cord-330553-sukrjl22	42	34	switching	switch	VBG
cord-330553-sukrjl22	42	35	to	to	IN
cord-330553-sukrjl22	42	36	an	an	DT
cord-330553-sukrjl22	42	37	M2	m2	JJ
cord-330553-sukrjl22	42	38	phenotype	phenotype	NN
cord-330553-sukrjl22	42	39	may	may	MD
cord-330553-sukrjl22	42	40	be	be	VB
cord-330553-sukrjl22	42	41	critical	critical	JJ
cord-330553-sukrjl22	42	42	in	in	IN
cord-330553-sukrjl22	42	43	preventing	prevent	VBG
cord-330553-sukrjl22	42	44	excessive	excessive	JJ
cord-330553-sukrjl22	42	45	damage	damage	NN
cord-330553-sukrjl22	42	46	due	due	IN
cord-330553-sukrjl22	42	47	to	to	IN
cord-330553-sukrjl22	42	48	inflammatory	inflammatory	JJ
cord-330553-sukrjl22	42	49	processes	process	NNS
cord-330553-sukrjl22	42	50	.	.	.
cord-330553-sukrjl22	43	1	For	for	IN
cord-330553-sukrjl22	43	2	the	the	DT
cord-330553-sukrjl22	43	3	purpose	purpose	NN
cord-330553-sukrjl22	43	4	of	of	IN
cord-330553-sukrjl22	43	5	this	this	DT
cord-330553-sukrjl22	43	6	review	review	NN
cord-330553-sukrjl22	43	7	,	,	,
cord-330553-sukrjl22	43	8	we	-PRON-	PRP
cord-330553-sukrjl22	43	9	will	will	MD
cord-330553-sukrjl22	43	10	mostly	mostly	RB
cord-330553-sukrjl22	43	11	be	be	VB
cord-330553-sukrjl22	43	12	referring	refer	VBG
cord-330553-sukrjl22	43	13	to	to	IN
cord-330553-sukrjl22	43	14	M1	M1	NNP
cord-330553-sukrjl22	43	15	microglial	microglial	JJ
cord-330553-sukrjl22	43	16	polarization	polarization	NN
cord-330553-sukrjl22	43	17	when	when	WRB
cord-330553-sukrjl22	43	18	discussing	discuss	VBG
cord-330553-sukrjl22	43	19	activation	activation	NN
cord-330553-sukrjl22	43	20	of	of	IN
cord-330553-sukrjl22	43	21	microglia	microglia	NNP
cord-330553-sukrjl22	43	22	.	.	.
cord-330553-sukrjl22	44	1	Several	several	JJ
cord-330553-sukrjl22	44	2	neurotropic	neurotropic	NNS
cord-330553-sukrjl22	44	3	viruses	virus	NNS
cord-330553-sukrjl22	44	4	have	have	VBP
cord-330553-sukrjl22	44	5	been	be	VBN
cord-330553-sukrjl22	44	6	shown	show	VBN
cord-330553-sukrjl22	44	7	to	to	TO
cord-330553-sukrjl22	44	8	induce	induce	VB
cord-330553-sukrjl22	44	9	microglia	microglia	JJ
cord-330553-sukrjl22	44	10	activation	activation	NN
cord-330553-sukrjl22	44	11	in	in	IN
cord-330553-sukrjl22	44	12	the	the	DT
cord-330553-sukrjl22	44	13	CNS	CNS	NNP
cord-330553-sukrjl22	44	14	following	follow	VBG
cord-330553-sukrjl22	44	15	infection	infection	NN
cord-330553-sukrjl22	44	16	,	,	,
cord-330553-sukrjl22	44	17	including	include	VBG
cord-330553-sukrjl22	44	18	Japanese	japanese	JJ
cord-330553-sukrjl22	44	19	encephalitis	encephalitis	RB
cord-330553-sukrjl22	44	20	virus	virus	NN
cord-330553-sukrjl22	44	21	[	[	-LRB-
cord-330553-sukrjl22	44	22	43	43	CD
cord-330553-sukrjl22	44	23	,	,	,
cord-330553-sukrjl22	44	24	44	44	CD
cord-330553-sukrjl22	44	25	]	]	-RRB-
cord-330553-sukrjl22	44	26	,	,	,
cord-330553-sukrjl22	44	27	Dengue	Dengue	NNP
cord-330553-sukrjl22	44	28	Virus	virus	NN
cord-330553-sukrjl22	44	29	[	[	-LRB-
cord-330553-sukrjl22	44	30	45	45	CD
cord-330553-sukrjl22	44	31	]	]	-RRB-
cord-330553-sukrjl22	44	32	,	,	,
cord-330553-sukrjl22	44	33	Zika	Zika	NNP
cord-330553-sukrjl22	44	34	virus	virus	NN
cord-330553-sukrjl22	44	35	[	[	-LRB-
cord-330553-sukrjl22	44	36	46	46	CD
cord-330553-sukrjl22	44	37	]	]	-RRB-
cord-330553-sukrjl22	44	38	,	,	,
cord-330553-sukrjl22	44	39	Tick	tick	VB
cord-330553-sukrjl22	44	40	-	-	HYPH
cord-330553-sukrjl22	44	41	borne	bear	VBN
cord-330553-sukrjl22	44	42	encephalitis	encephalitis	JJ
cord-330553-sukrjl22	44	43	virus	virus	NN
cord-330553-sukrjl22	44	44	[	[	-LRB-
cord-330553-sukrjl22	44	45	47	47	CD
cord-330553-sukrjl22	44	46	]	]	-RRB-
cord-330553-sukrjl22	44	47	,	,	,
cord-330553-sukrjl22	44	48	reovirus	reovirus	NNP
cord-330553-sukrjl22	44	49	[	[	-LRB-
cord-330553-sukrjl22	44	50	48	48	CD
cord-330553-sukrjl22	44	51	]	]	-RRB-
cord-330553-sukrjl22	44	52	,	,	,
cord-330553-sukrjl22	44	53	and	and	CC
cord-330553-sukrjl22	44	54	mouse	mouse	NN
cord-330553-sukrjl22	44	55	hepatitis	hepatitis	NN
cord-330553-sukrjl22	44	56	virus	virus	NN
cord-330553-sukrjl22	44	57	[	[	-LRB-
cord-330553-sukrjl22	44	58	49	49	CD
cord-330553-sukrjl22	44	59	,	,	,
cord-330553-sukrjl22	44	60	50	50	CD
cord-330553-sukrjl22	44	61	]	]	-RRB-
cord-330553-sukrjl22	44	62	.	.	.
cord-330553-sukrjl22	45	1	Evidence	evidence	NN
cord-330553-sukrjl22	45	2	that	that	IN
cord-330553-sukrjl22	45	3	microglia	microglia	NNS
cord-330553-sukrjl22	45	4	are	be	VBP
cord-330553-sukrjl22	45	5	activated	activate	VBN
cord-330553-sukrjl22	45	6	during	during	IN
cord-330553-sukrjl22	45	7	WNV	WNV	NNP
cord-330553-sukrjl22	45	8	-	-	HYPH
cord-330553-sukrjl22	45	9	induced	induce	VBN
cord-330553-sukrjl22	45	10	CNS	CNS	NNP
cord-330553-sukrjl22	45	11	disease	disease	NN
cord-330553-sukrjl22	45	12	in	in	IN
cord-330553-sukrjl22	45	13	humans	human	NNS
cord-330553-sukrjl22	45	14	includes	include	VBZ
cord-330553-sukrjl22	45	15	the	the	DT
cord-330553-sukrjl22	45	16	presence	presence	NN
cord-330553-sukrjl22	45	17	of	of	IN
cord-330553-sukrjl22	45	18	microglial	microglial	JJ
cord-330553-sukrjl22	45	19	nodules	nodule	NNS
cord-330553-sukrjl22	45	20	and	and	CC
cord-330553-sukrjl22	45	21	increased	increase	VBN
cord-330553-sukrjl22	45	22	proliferation	proliferation	NN
cord-330553-sukrjl22	45	23	[	[	-LRB-
cord-330553-sukrjl22	45	24	51	51	CD
cord-330553-sukrjl22	45	25	,	,	,
cord-330553-sukrjl22	45	26	52	52	CD
cord-330553-sukrjl22	45	27	]	]	-RRB-
cord-330553-sukrjl22	45	28	.	.	.
cord-330553-sukrjl22	46	1	Activated	activate	VBN
cord-330553-sukrjl22	46	2	microglia	microglia	NNS
cord-330553-sukrjl22	46	3	are	be	VBP
cord-330553-sukrjl22	46	4	also	also	RB
cord-330553-sukrjl22	46	5	seen	see	VBN
cord-330553-sukrjl22	46	6	in	in	IN
cord-330553-sukrjl22	46	7	the	the	DT
cord-330553-sukrjl22	46	8	CNS	CNS	NNP
cord-330553-sukrjl22	46	9	of	of	IN
cord-330553-sukrjl22	46	10	mice	mouse	NNS
cord-330553-sukrjl22	46	11	infected	infect	VBN
cord-330553-sukrjl22	46	12	with	with	IN
cord-330553-sukrjl22	46	13	WNV	WNV	NNP
cord-330553-sukrjl22	46	14	[	[	-LRB-
cord-330553-sukrjl22	46	15	53	53	CD
cord-330553-sukrjl22	46	16	]	]	-RRB-
cord-330553-sukrjl22	47	1	[	[	-LRB-
cord-330553-sukrjl22	47	2	54	54	CD
cord-330553-sukrjl22	47	3	]	]	-RRB-
cord-330553-sukrjl22	48	1	[	[	-LRB-
cord-330553-sukrjl22	48	2	55	55	CD
cord-330553-sukrjl22	48	3	]	]	-RRB-
cord-330553-sukrjl22	48	4	and	and	CC
cord-330553-sukrjl22	48	5	in	in	IN
cord-330553-sukrjl22	48	6	WNV	WNV	NNP
cord-330553-sukrjl22	48	7	-	-	HYPH
cord-330553-sukrjl22	48	8	infected	infect	VBN
cord-330553-sukrjl22	48	9	ex	ex	FW
cord-330553-sukrjl22	48	10	vivo	vivo	NN
cord-330553-sukrjl22	48	11	brain	brain	NN
cord-330553-sukrjl22	48	12	and	and	CC
cord-330553-sukrjl22	48	13	spinal	spinal	JJ
cord-330553-sukrjl22	48	14	cord	cord	NN
cord-330553-sukrjl22	48	15	slice	slice	NN
cord-330553-sukrjl22	48	16	cultures	culture	NNS
cord-330553-sukrjl22	48	17	[	[	-LRB-
cord-330553-sukrjl22	48	18	21	21	CD
cord-330553-sukrjl22	48	19	,	,	,
cord-330553-sukrjl22	48	20	41	41	CD
cord-330553-sukrjl22	48	21	]	]	-RRB-
cord-330553-sukrjl22	48	22	.	.	.
cord-330553-sukrjl22	49	1	The	the	DT
cord-330553-sukrjl22	49	2	use	use	NN
cord-330553-sukrjl22	49	3	of	of	IN
cord-330553-sukrjl22	49	4	ex	ex	FW
cord-330553-sukrjl22	49	5	vivo	vivo	NN
cord-330553-sukrjl22	49	6	slice	slice	NN
cord-330553-sukrjl22	49	7	cultures	culture	NNS
cord-330553-sukrjl22	49	8	allows	allow	VBZ
cord-330553-sukrjl22	49	9	for	for	IN
cord-330553-sukrjl22	49	10	isolation	isolation	NN
cord-330553-sukrjl22	49	11	of	of	IN
cord-330553-sukrjl22	49	12	the	the	DT
cord-330553-sukrjl22	49	13	CNS	CNS	NNP
cord-330553-sukrjl22	49	14	immune	immune	NN
cord-330553-sukrjl22	49	15	system	system	NN
cord-330553-sukrjl22	49	16	from	from	IN
cord-330553-sukrjl22	49	17	the	the	DT
cord-330553-sukrjl22	49	18	peripheral	peripheral	JJ
cord-330553-sukrjl22	49	19	immune	immune	JJ
cord-330553-sukrjl22	49	20	response	response	NN
cord-330553-sukrjl22	49	21	.	.	.
cord-330553-sukrjl22	50	1	In	in	IN
cord-330553-sukrjl22	50	2	this	this	DT
cord-330553-sukrjl22	50	3	method	method	NN
cord-330553-sukrjl22	50	4	,	,	,
cord-330553-sukrjl22	50	5	spinal	spinal	JJ
cord-330553-sukrjl22	50	6	cords	cord	NNS
cord-330553-sukrjl22	50	7	or	or	CC
cord-330553-sukrjl22	50	8	brains	brain	NNS
cord-330553-sukrjl22	50	9	are	be	VBP
cord-330553-sukrjl22	50	10	harvested	harvest	VBN
cord-330553-sukrjl22	50	11	from	from	IN
cord-330553-sukrjl22	50	12	neonatal	neonatal	JJ
cord-330553-sukrjl22	50	13	mice	mouse	NNS
cord-330553-sukrjl22	50	14	and	and	CC
cord-330553-sukrjl22	50	15	used	use	VBD
cord-330553-sukrjl22	50	16	to	to	TO
cord-330553-sukrjl22	50	17	create	create	VB
cord-330553-sukrjl22	50	18	300-µm	300-µm	CD
cord-330553-sukrjl22	50	19	-	-	HYPH
cord-330553-sukrjl22	50	20	thick	thick	JJ
cord-330553-sukrjl22	50	21	slice	slice	NN
cord-330553-sukrjl22	50	22	cultures	culture	NNS
cord-330553-sukrjl22	50	23	,	,	,
cord-330553-sukrjl22	50	24	which	which	WDT
cord-330553-sukrjl22	50	25	are	be	VBP
cord-330553-sukrjl22	50	26	incubated	incubate	VBN
cord-330553-sukrjl22	50	27	on	on	IN
cord-330553-sukrjl22	50	28	culture	culture	NN
cord-330553-sukrjl22	50	29	inserts	insert	NNS
cord-330553-sukrjl22	50	30	prior	prior	RB
cord-330553-sukrjl22	50	31	to	to	IN
cord-330553-sukrjl22	50	32	infection	infection	NN
cord-330553-sukrjl22	50	33	.	.	.
cord-330553-sukrjl22	51	1	Using	use	VBG
cord-330553-sukrjl22	51	2	this	this	DT
cord-330553-sukrjl22	51	3	model	model	NN
cord-330553-sukrjl22	51	4	,	,	,
cord-330553-sukrjl22	51	5	activated	activate	VBN
cord-330553-sukrjl22	51	6	microglia	microglia	NNS
cord-330553-sukrjl22	51	7	were	be	VBD
cord-330553-sukrjl22	51	8	identified	identify	VBN
cord-330553-sukrjl22	51	9	following	follow	VBG
cord-330553-sukrjl22	51	10	WNV	WNV	NNP
cord-330553-sukrjl22	51	11	infection	infection	NN
cord-330553-sukrjl22	51	12	by	by	IN
cord-330553-sukrjl22	51	13	increased	increase	VBN
cord-330553-sukrjl22	51	14	expression	expression	NN
cord-330553-sukrjl22	51	15	of	of	IN
cord-330553-sukrjl22	51	16	ionized	ionized	JJ
cord-330553-sukrjl22	51	17	calcium	calcium	NN
cord-330553-sukrjl22	51	18	binding	bind	VBG
cord-330553-sukrjl22	51	19	adaptor	adaptor	NN
cord-330553-sukrjl22	51	20	molecule	molecule	NN
cord-330553-sukrjl22	51	21	1	1	CD
cord-330553-sukrjl22	51	22	(	(	-LRB-
cord-330553-sukrjl22	51	23	Iba1	Iba1	NNP
cord-330553-sukrjl22	51	24	)	)	-RRB-
cord-330553-sukrjl22	51	25	[	[	-LRB-
cord-330553-sukrjl22	51	26	21	21	CD
cord-330553-sukrjl22	51	27	,	,	,
cord-330553-sukrjl22	51	28	41	41	CD
cord-330553-sukrjl22	51	29	]	]	-RRB-
cord-330553-sukrjl22	51	30	,	,	,
cord-330553-sukrjl22	51	31	a	a	DT
cord-330553-sukrjl22	51	32	microglia	microglia	NN
cord-330553-sukrjl22	51	33	-	-	HYPH
cord-330553-sukrjl22	51	34	specific	specific	JJ
cord-330553-sukrjl22	51	35	marker	marker	NN
cord-330553-sukrjl22	51	36	[	[	-LRB-
cord-330553-sukrjl22	51	37	56	56	CD
cord-330553-sukrjl22	51	38	]	]	-RRB-
cord-330553-sukrjl22	51	39	.	.	.
cord-330553-sukrjl22	52	1	In	in	IN
cord-330553-sukrjl22	52	2	addition	addition	NN
cord-330553-sukrjl22	52	3	,	,	,
cord-330553-sukrjl22	52	4	microglia	microglia	NNS
cord-330553-sukrjl22	52	5	in	in	IN
cord-330553-sukrjl22	52	6	WNV	WNV	NNP
cord-330553-sukrjl22	52	7	-	-	HYPH
cord-330553-sukrjl22	52	8	infected	infect	VBN
cord-330553-sukrjl22	52	9	ex	ex	FW
cord-330553-sukrjl22	52	10	vivo	vivo	NN
cord-330553-sukrjl22	52	11	slices	slice	NNS
cord-330553-sukrjl22	52	12	were	be	VBD
cord-330553-sukrjl22	52	13	increased	increase	VBN
cord-330553-sukrjl22	52	14	in	in	IN
cord-330553-sukrjl22	52	15	both	both	DT
cord-330553-sukrjl22	52	16	size	size	NN
cord-330553-sukrjl22	52	17	and	and	CC
cord-330553-sukrjl22	52	18	number	number	NN
cord-330553-sukrjl22	52	19	compared	compare	VBN
cord-330553-sukrjl22	52	20	to	to	IN
cord-330553-sukrjl22	52	21	uninfected	uninfected	JJ
cord-330553-sukrjl22	52	22	slices	slice	NNS
cord-330553-sukrjl22	52	23	and	and	CC
cord-330553-sukrjl22	52	24	displayed	display	VBD
cord-330553-sukrjl22	52	25	an	an	DT
cord-330553-sukrjl22	52	26	amoeboid	amoeboid	JJ
cord-330553-sukrjl22	52	27	phenotype	phenotype	NN
cord-330553-sukrjl22	52	28	[	[	-LRB-
cord-330553-sukrjl22	52	29	21	21	CD
cord-330553-sukrjl22	52	30	,	,	,
cord-330553-sukrjl22	52	31	41	41	CD
cord-330553-sukrjl22	52	32	]	]	-RRB-
cord-330553-sukrjl22	52	33	.	.	.
cord-330553-sukrjl22	53	1	Distinct	distinct	JJ
cord-330553-sukrjl22	53	2	microglia	microglia	JJ
cord-330553-sukrjl22	53	3	cell	cell	NN
cord-330553-sukrjl22	53	4	processes	process	NNS
cord-330553-sukrjl22	53	5	related	relate	VBN
cord-330553-sukrjl22	53	6	to	to	IN
cord-330553-sukrjl22	53	7	cell	cell	NN
cord-330553-sukrjl22	53	8	motility	motility	NN
cord-330553-sukrjl22	53	9	and	and	CC
cord-330553-sukrjl22	53	10	phagocytosis	phagocytosis	NN
cord-330553-sukrjl22	53	11	of	of	IN
cord-330553-sukrjl22	53	12	WNV	WNV	NNP
cord-330553-sukrjl22	53	13	-	-	HYPH
cord-330553-sukrjl22	53	14	infected	infect	VBN
cord-330553-sukrjl22	53	15	cells	cell	NNS
cord-330553-sukrjl22	53	16	and	and	CC
cord-330553-sukrjl22	53	17	antigenic	antigenic	JJ
cord-330553-sukrjl22	53	18	debris	debris	NN
cord-330553-sukrjl22	53	19	were	be	VBD
cord-330553-sukrjl22	53	20	seen	see	VBN
cord-330553-sukrjl22	53	21	in	in	IN
cord-330553-sukrjl22	53	22	WNV	WNV	NNP
cord-330553-sukrjl22	53	23	-	-	HYPH
cord-330553-sukrjl22	53	24	infected	infect	VBN
cord-330553-sukrjl22	53	25	ex	ex	FW
cord-330553-sukrjl22	53	26	vivo	vivo	NN
cord-330553-sukrjl22	53	27	slice	slice	NN
cord-330553-sukrjl22	53	28	cultures	culture	NNS
cord-330553-sukrjl22	53	29	(	(	-LRB-
cord-330553-sukrjl22	53	30	Figure	figure	NN
cord-330553-sukrjl22	53	31	1	1	CD
cord-330553-sukrjl22	53	32	)	)	-RRB-
cord-330553-sukrjl22	53	33	,	,	,
cord-330553-sukrjl22	53	34	including	include	VBG
cord-330553-sukrjl22	53	35	microglial	microglial	JJ
cord-330553-sukrjl22	53	36	cellular	cellular	JJ
cord-330553-sukrjl22	53	37	projections	projection	NNS
cord-330553-sukrjl22	53	38	stretching	stretch	VBG
cord-330553-sukrjl22	53	39	over	over	IN
cord-330553-sukrjl22	53	40	a	a	DT
cord-330553-sukrjl22	53	41	range	range	NN
cord-330553-sukrjl22	53	42	of	of	IN
cord-330553-sukrjl22	53	43	distances	distance	NNS
cord-330553-sukrjl22	53	44	to	to	TO
cord-330553-sukrjl22	53	45	reach	reach	VB
cord-330553-sukrjl22	53	46	WNV	WNV	NNP
cord-330553-sukrjl22	53	47	-	-	HYPH
cord-330553-sukrjl22	53	48	infected	infect	VBN
cord-330553-sukrjl22	53	49	cells	cell	NNS
cord-330553-sukrjl22	53	50	,	,	,
cord-330553-sukrjl22	53	51	which	which	WDT
cord-330553-sukrjl22	53	52	were	be	VBD
cord-330553-sukrjl22	53	53	often	often	RB
cord-330553-sukrjl22	53	54	filopodial	filopodial	JJ
cord-330553-sukrjl22	53	55	/	/	SYM
cord-330553-sukrjl22	53	56	lamellipodial	lamellipodial	NN
cord-330553-sukrjl22	53	57	in	in	IN
cord-330553-sukrjl22	53	58	appearance	appearance	NN
cord-330553-sukrjl22	53	59	(	(	-LRB-
cord-330553-sukrjl22	53	60	Figure	figure	NN
cord-330553-sukrjl22	53	61	1A	1a	NN
cord-330553-sukrjl22	53	62	)	)	-RRB-
cord-330553-sukrjl22	53	63	,	,	,
cord-330553-sukrjl22	53	64	reflecting	reflect	VBG
cord-330553-sukrjl22	53	65	microglia	microglia	NNS
cord-330553-sukrjl22	53	66	with	with	IN
cord-330553-sukrjl22	53	67	amoeboid	amoeboid	JJ
cord-330553-sukrjl22	53	68	morphology	morphology	NN
cord-330553-sukrjl22	53	69	[	[	-LRB-
cord-330553-sukrjl22	53	70	41	41	CD
cord-330553-sukrjl22	53	71	]	]	-RRB-
cord-330553-sukrjl22	53	72	.	.	.
cord-330553-sukrjl22	54	1	These	these	DT
cord-330553-sukrjl22	54	2	microglia	microglia	JJ
cord-330553-sukrjl22	54	3	cell	cell	NN
cord-330553-sukrjl22	54	4	processes	process	NNS
cord-330553-sukrjl22	54	5	were	be	VBD
cord-330553-sukrjl22	54	6	observed	observe	VBN
cord-330553-sukrjl22	54	7	contacting	contact	VBG
cord-330553-sukrjl22	54	8	infected	infected	JJ
cord-330553-sukrjl22	54	9	cells	cell	NNS
cord-330553-sukrjl22	54	10	and	and	CC
cord-330553-sukrjl22	54	11	initiating	initiate	VBG
cord-330553-sukrjl22	54	12	engulfment	engulfment	NN
cord-330553-sukrjl22	54	13	activity	activity	NN
cord-330553-sukrjl22	54	14	(	(	-LRB-
cord-330553-sukrjl22	54	15	Figure	figure	NN
cord-330553-sukrjl22	54	16	1B	1b	NN
cord-330553-sukrjl22	54	17	-E	-E	JJS
cord-330553-sukrjl22	54	18	)	)	-RRB-
cord-330553-sukrjl22	54	19	.	.	.
cord-330553-sukrjl22	55	1	The	the	DT
cord-330553-sukrjl22	55	2	formation	formation	NN
cord-330553-sukrjl22	55	3	of	of	IN
cord-330553-sukrjl22	55	4	phagosomes	phagosomes	NNP
cord-330553-sukrjl22	55	5	was	be	VBD
cord-330553-sukrjl22	55	6	also	also	RB
cord-330553-sukrjl22	55	7	prevalent	prevalent	JJ
cord-330553-sukrjl22	55	8	(	(	-LRB-
cord-330553-sukrjl22	55	9	Figure	figure	NN
cord-330553-sukrjl22	55	10	1F	1f	CD
cord-330553-sukrjl22	55	11	)	)	-RRB-
cord-330553-sukrjl22	55	12	.	.	.
cord-330553-sukrjl22	56	1	Notably	notably	RB
cord-330553-sukrjl22	56	2	,	,	,
cord-330553-sukrjl22	56	3	microglia	microglia	NN
cord-330553-sukrjl22	56	4	virtually	virtually	RB
cord-330553-sukrjl22	56	5	never	never	RB
cord-330553-sukrjl22	56	6	appeared	appear	VBD
cord-330553-sukrjl22	56	7	to	to	TO
cord-330553-sukrjl22	56	8	be	be	VB
cord-330553-sukrjl22	56	9	infected	infect	VBN
cord-330553-sukrjl22	56	10	themselves	-PRON-	PRP
cord-330553-sukrjl22	56	11	,	,	,
cord-330553-sukrjl22	56	12	despite	despite	IN
cord-330553-sukrjl22	56	13	taking	take	VBG
cord-330553-sukrjl22	56	14	in	in	RP
cord-330553-sukrjl22	56	15	material	material	NN
cord-330553-sukrjl22	56	16	(	(	-LRB-
cord-330553-sukrjl22	56	17	cells	cell	NNS
cord-330553-sukrjl22	56	18	and	and	CC
cord-330553-sukrjl22	56	19	debris	debris	NN
cord-330553-sukrjl22	56	20	)	)	-RRB-
cord-330553-sukrjl22	56	21	that	that	WDT
cord-330553-sukrjl22	56	22	stained	stain	VBD
cord-330553-sukrjl22	56	23	positive	positive	JJ
cord-330553-sukrjl22	56	24	for	for	IN
cord-330553-sukrjl22	56	25	WNV	WNV	NNP
cord-330553-sukrjl22	56	26	antigens	antigen	NNS
cord-330553-sukrjl22	56	27	.	.	.
cord-330553-sukrjl22	57	1	Intercellular	intercellular	JJ
cord-330553-sukrjl22	57	2	communication	communication	NN
cord-330553-sukrjl22	57	3	via	via	IN
cord-330553-sukrjl22	57	4	cytokine	cytokine	NN
cord-330553-sukrjl22	57	5	/	/	SYM
cord-330553-sukrjl22	57	6	chemokine	chemokine	NN
cord-330553-sukrjl22	57	7	signaling	signal	VBG
cord-330553-sukrjl22	57	8	drives	drive	VBZ
cord-330553-sukrjl22	57	9	inflammatory	inflammatory	JJ
cord-330553-sukrjl22	57	10	responses	response	NNS
cord-330553-sukrjl22	57	11	during	during	IN
cord-330553-sukrjl22	57	12	viral	viral	JJ
cord-330553-sukrjl22	57	13	infections	infection	NNS
cord-330553-sukrjl22	57	14	of	of	IN
cord-330553-sukrjl22	57	15	the	the	DT
cord-330553-sukrjl22	57	16	CNS	CNS	NNP
cord-330553-sukrjl22	57	17	[	[	-LRB-
cord-330553-sukrjl22	57	18	40	40	CD
cord-330553-sukrjl22	57	19	,	,	,
cord-330553-sukrjl22	57	20	57	57	CD
cord-330553-sukrjl22	57	21	]	]	-RRB-
cord-330553-sukrjl22	57	22	.	.	.
cord-330553-sukrjl22	58	1	Infection	infection	NN
cord-330553-sukrjl22	58	2	of	of	IN
cord-330553-sukrjl22	58	3	CNS	CNS	NNP
cord-330553-sukrjl22	58	4	tissue	tissue	NN
cord-330553-sukrjl22	58	5	with	with	IN
cord-330553-sukrjl22	58	6	WNV	WNV	NNP
cord-330553-sukrjl22	58	7	in	in	IN
cord-330553-sukrjl22	58	8	vivo	vivo	NNP
cord-330553-sukrjl22	58	9	[	[	-LRB-
cord-330553-sukrjl22	58	10	21	21	CD
cord-330553-sukrjl22	58	11	,	,	,
cord-330553-sukrjl22	58	12	58	58	CD
cord-330553-sukrjl22	58	13	]	]	-RRB-
cord-330553-sukrjl22	58	14	and	and	CC
cord-330553-sukrjl22	58	15	in	in	IN
cord-330553-sukrjl22	58	16	ex	ex	FW
cord-330553-sukrjl22	58	17	vivo	vivo	NN
cord-330553-sukrjl22	58	18	[	[	-LRB-
cord-330553-sukrjl22	58	19	41	41	CD
cord-330553-sukrjl22	58	20	]	]	-RRB-
cord-330553-sukrjl22	58	21	and	and	CC
cord-330553-sukrjl22	58	22	in	in	IN
cord-330553-sukrjl22	58	23	vitro	vitro	FW
cord-330553-sukrjl22	58	24	[	[	-LRB-
cord-330553-sukrjl22	58	25	23	23	CD
cord-330553-sukrjl22	58	26	]	]	-RRB-
cord-330553-sukrjl22	58	27	models	model	NNS
cord-330553-sukrjl22	58	28	of	of	IN
cord-330553-sukrjl22	58	29	WNV	WNV	NNP
cord-330553-sukrjl22	58	30	pathogenesis	pathogenesis	NN
cord-330553-sukrjl22	58	31	results	result	NNS
cord-330553-sukrjl22	58	32	in	in	IN
cord-330553-sukrjl22	58	33	increased	increase	VBN
cord-330553-sukrjl22	58	34	expression	expression	NN
cord-330553-sukrjl22	58	35	of	of	IN
cord-330553-sukrjl22	58	36	proinflammatory	proinflammatory	JJ
cord-330553-sukrjl22	58	37	cytokines	cytokine	NNS
cord-330553-sukrjl22	58	38	and	and	CC
cord-330553-sukrjl22	58	39	chemokines	chemokine	NNS
cord-330553-sukrjl22	58	40	associated	associate	VBN
cord-330553-sukrjl22	58	41	with	with	IN
cord-330553-sukrjl22	58	42	microglial	microglial	JJ
cord-330553-sukrjl22	58	43	activation	activation	NN
cord-330553-sukrjl22	58	44	including	include	VBG
cord-330553-sukrjl22	58	45	C	C	NNP
cord-330553-sukrjl22	58	46	-	-	HYPH
cord-330553-sukrjl22	58	47	X	x	NN
cord-330553-sukrjl22	58	48	-	-	HYPH
cord-330553-sukrjl22	58	49	C	c	NN
cord-330553-sukrjl22	58	50	motif	motif	NN
cord-330553-sukrjl22	58	51	chemokine	chemokine	NN
cord-330553-sukrjl22	58	52	10	10	CD
cord-330553-sukrjl22	58	53	(	(	-LRB-
cord-330553-sukrjl22	58	54	CXCL10	CXCL10	NNP
cord-330553-sukrjl22	58	55	)	)	-RRB-
cord-330553-sukrjl22	58	56	,	,	,
cord-330553-sukrjl22	58	57	CXCL1	CXCL1	NNP
cord-330553-sukrjl22	58	58	,	,	,
cord-330553-sukrjl22	58	59	CCL5	CCL5	NNP
cord-330553-sukrjl22	58	60	,	,	,
cord-330553-sukrjl22	58	61	CCL3	CCL3	NNP
cord-330553-sukrjl22	58	62	,	,	,
cord-330553-sukrjl22	58	63	CCL2	CCL2	NNP
cord-330553-sukrjl22	58	64	,	,	,
cord-330553-sukrjl22	58	65	tumor	tumor	NN
cord-330553-sukrjl22	58	66	necrosis	necrosis	NN
cord-330553-sukrjl22	58	67	factor	factor	NN
cord-330553-sukrjl22	58	68	alpha	alpha	NN
cord-330553-sukrjl22	58	69	(	(	-LRB-
cord-330553-sukrjl22	58	70	TNF	TNF	NNP
cord-330553-sukrjl22	58	71	-	-	HYPH
cord-330553-sukrjl22	58	72	α	α	NNP
cord-330553-sukrjl22	58	73	)	)	-RRB-
cord-330553-sukrjl22	58	74	,	,	,
cord-330553-sukrjl22	58	75	TNF	tnf	NN
cord-330553-sukrjl22	58	76	-	-	HYPH
cord-330553-sukrjl22	58	77	related	relate	VBN
cord-330553-sukrjl22	58	78	apoptosis	apoptosis	NN
cord-330553-sukrjl22	58	79	-	-	HYPH
cord-330553-sukrjl22	58	80	inducing	induce	VBG
cord-330553-sukrjl22	58	81	ligand	ligand	NN
cord-330553-sukrjl22	58	82	(	(	-LRB-
cord-330553-sukrjl22	58	83	TRAIL	TRAIL	NNP
cord-330553-sukrjl22	58	84	)	)	-RRB-
cord-330553-sukrjl22	58	85	,	,	,
cord-330553-sukrjl22	58	86	and	and	CC
cord-330553-sukrjl22	58	87	interleukin-6	interleukin-6	NNP
cord-330553-sukrjl22	59	1	(	(	-LRB-
cord-330553-sukrjl22	59	2	IL-6	IL-6	NNP
cord-330553-sukrjl22	59	3	)	)	-RRB-
cord-330553-sukrjl22	59	4	[	[	-LRB-
cord-330553-sukrjl22	59	5	40	40	CD
cord-330553-sukrjl22	59	6	]	]	-RRB-
cord-330553-sukrjl22	59	7	.	.	.
cord-330553-sukrjl22	60	1	These	these	DT
cord-330553-sukrjl22	60	2	cytokines	cytokine	NNS
cord-330553-sukrjl22	60	3	are	be	VBP
cord-330553-sukrjl22	60	4	involved	involve	VBN
cord-330553-sukrjl22	60	5	in	in	IN
cord-330553-sukrjl22	60	6	inflammatory	inflammatory	JJ
cord-330553-sukrjl22	60	7	processes	process	NNS
cord-330553-sukrjl22	60	8	and	and	CC
cord-330553-sukrjl22	60	9	activating	activate	VBG
cord-330553-sukrjl22	60	10	/	/	SYM
cord-330553-sukrjl22	60	11	recruiting	recruit	VBG
cord-330553-sukrjl22	60	12	immune	immune	JJ
cord-330553-sukrjl22	60	13	cells	cell	NNS
cord-330553-sukrjl22	60	14	such	such	JJ
cord-330553-sukrjl22	60	15	as	as	IN
cord-330553-sukrjl22	60	16	T	T	NNP
cord-330553-sukrjl22	60	17	cells	cell	NNS
cord-330553-sukrjl22	60	18	[	[	-LRB-
cord-330553-sukrjl22	60	19	59	59	CD
cord-330553-sukrjl22	60	20	]	]	-RRB-
cord-330553-sukrjl22	60	21	.	.	.
cord-330553-sukrjl22	61	1	Inhibition	inhibition	NN
cord-330553-sukrjl22	61	2	of	of	IN
cord-330553-sukrjl22	61	3	these	these	DT
cord-330553-sukrjl22	61	4	chemokines	chemokine	NNS
cord-330553-sukrjl22	61	5	/	/	SYM
cord-330553-sukrjl22	61	6	cytokines	cytokine	NNS
cord-330553-sukrjl22	61	7	following	follow	VBG
cord-330553-sukrjl22	61	8	treatment	treatment	NN
cord-330553-sukrjl22	61	9	with	with	IN
cord-330553-sukrjl22	61	10	minocycline	minocycline	NNP
cord-330553-sukrjl22	61	11	resulted	result	VBD
cord-330553-sukrjl22	61	12	in	in	IN
cord-330553-sukrjl22	61	13	decreased	decrease	VBN
cord-330553-sukrjl22	61	14	neuronal	neuronal	JJ
cord-330553-sukrjl22	61	15	cell	cell	NN
cord-330553-sukrjl22	61	16	death	death	NN
cord-330553-sukrjl22	61	17	following	follow	VBG
cord-330553-sukrjl22	61	18	WNV	WNV	NNP
cord-330553-sukrjl22	61	19	infection	infection	NN
cord-330553-sukrjl22	61	20	of	of	IN
cord-330553-sukrjl22	61	21	ex	ex	FW
cord-330553-sukrjl22	61	22	vivo	vivo	FW
cord-330553-sukrjl22	61	23	spinal	spinal	JJ
cord-330553-sukrjl22	61	24	cord	cord	NN
cord-330553-sukrjl22	61	25	slice	slice	NN
cord-330553-sukrjl22	61	26	cultures	culture	NNS
cord-330553-sukrjl22	61	27	[	[	-LRB-
cord-330553-sukrjl22	61	28	42	42	CD
cord-330553-sukrjl22	61	29	]	]	-RRB-
cord-330553-sukrjl22	61	30	,	,	,
cord-330553-sukrjl22	61	31	suggesting	suggest	VBG
cord-330553-sukrjl22	61	32	they	-PRON-	PRP
cord-330553-sukrjl22	61	33	contribute	contribute	VBP
cord-330553-sukrjl22	61	34	to	to	IN
cord-330553-sukrjl22	61	35	disease	disease	NN
cord-330553-sukrjl22	61	36	;	;	:
cord-330553-sukrjl22	61	37	however	however	RB
cord-330553-sukrjl22	61	38	,	,	,
cord-330553-sukrjl22	61	39	depletion	depletion	NN
cord-330553-sukrjl22	61	40	of	of	IN
cord-330553-sukrjl22	61	41	microglia	microglia	NN
cord-330553-sukrjl22	61	42	did	do	VBD
cord-330553-sukrjl22	61	43	not	not	RB
cord-330553-sukrjl22	61	44	significantly	significantly	RB
cord-330553-sukrjl22	61	45	change	change	VB
cord-330553-sukrjl22	61	46	chemokine	chemokine	NN
cord-330553-sukrjl22	61	47	/	/	SYM
cord-330553-sukrjl22	61	48	cytokine	cytokine	NN
cord-330553-sukrjl22	61	49	expression	expression	NN
cord-330553-sukrjl22	61	50	in	in	IN
cord-330553-sukrjl22	61	51	the	the	DT
cord-330553-sukrjl22	61	52	brains	brain	NNS
cord-330553-sukrjl22	61	53	of	of	IN
cord-330553-sukrjl22	61	54	WNV	WNV	NNP
cord-330553-sukrjl22	61	55	-	-	HYPH
cord-330553-sukrjl22	61	56	infected	infect	VBN
cord-330553-sukrjl22	61	57	mice	mouse	NNS
cord-330553-sukrjl22	61	58	[	[	-LRB-
cord-330553-sukrjl22	61	59	60	60	CD
cord-330553-sukrjl22	61	60	]	]	-RRB-
cord-330553-sukrjl22	61	61	so	so	CC
cord-330553-sukrjl22	61	62	it	-PRON-	PRP
cord-330553-sukrjl22	61	63	is	be	VBZ
cord-330553-sukrjl22	61	64	unclear	unclear	JJ
cord-330553-sukrjl22	61	65	what	what	WDT
cord-330553-sukrjl22	61	66	role	role	NN
cord-330553-sukrjl22	61	67	microglia	microglia	NN
cord-330553-sukrjl22	61	68	play	play	VBP
cord-330553-sukrjl22	61	69	in	in	IN
cord-330553-sukrjl22	61	70	the	the	DT
cord-330553-sukrjl22	61	71	production	production	NN
cord-330553-sukrjl22	61	72	of	of	IN
cord-330553-sukrjl22	61	73	these	these	DT
cord-330553-sukrjl22	61	74	proteins	protein	NNS
cord-330553-sukrjl22	61	75	.	.	.
cord-330553-sukrjl22	62	1	Based	base	VBN
cord-330553-sukrjl22	62	2	on	on	IN
cord-330553-sukrjl22	62	3	the	the	DT
cord-330553-sukrjl22	62	4	evidence	evidence	NN
cord-330553-sukrjl22	62	5	presented	present	VBN
cord-330553-sukrjl22	62	6	above	above	RB
cord-330553-sukrjl22	62	7	,	,	,
cord-330553-sukrjl22	62	8	it	-PRON-	PRP
cord-330553-sukrjl22	62	9	can	can	MD
cord-330553-sukrjl22	62	10	be	be	VB
cord-330553-sukrjl22	62	11	concluded	conclude	VBN
cord-330553-sukrjl22	62	12	that	that	IN
cord-330553-sukrjl22	62	13	microglia	microglia	NNP
cord-330553-sukrjl22	62	14	become	become	VBP
cord-330553-sukrjl22	62	15	activated	activate	VBN
cord-330553-sukrjl22	62	16	following	follow	VBG
cord-330553-sukrjl22	62	17	infection	infection	NN
cord-330553-sukrjl22	62	18	of	of	IN
cord-330553-sukrjl22	62	19	the	the	DT
cord-330553-sukrjl22	62	20	CNS	CNS	NNP
cord-330553-sukrjl22	62	21	with	with	IN
cord-330553-sukrjl22	62	22	WNV	WNV	NNP
cord-330553-sukrjl22	62	23	.	.	.
cord-330553-sukrjl22	63	1	These	these	DT
cord-330553-sukrjl22	63	2	activated	activate	VBN
cord-330553-sukrjl22	63	3	microglia	microglia	NNS
cord-330553-sukrjl22	63	4	can	can	MD
cord-330553-sukrjl22	63	5	initiate	initiate	VB
cord-330553-sukrjl22	63	6	an	an	DT
cord-330553-sukrjl22	63	7	immune	immune	JJ
cord-330553-sukrjl22	63	8	response	response	NN
cord-330553-sukrjl22	63	9	that	that	WDT
cord-330553-sukrjl22	63	10	is	be	VBZ
cord-330553-sukrjl22	63	11	intrinsic	intrinsic	JJ
cord-330553-sukrjl22	63	12	to	to	IN
cord-330553-sukrjl22	63	13	the	the	DT
cord-330553-sukrjl22	63	14	CNS	CNS	NNP
cord-330553-sukrjl22	63	15	and	and	CC
cord-330553-sukrjl22	63	16	does	do	VBZ
cord-330553-sukrjl22	63	17	not	not	RB
cord-330553-sukrjl22	63	18	require	require	VB
cord-330553-sukrjl22	63	19	input	input	NN
cord-330553-sukrjl22	63	20	from	from	IN
cord-330553-sukrjl22	63	21	the	the	DT
cord-330553-sukrjl22	63	22	peripheral	peripheral	JJ
cord-330553-sukrjl22	63	23	immune	immune	JJ
cord-330553-sukrjl22	63	24	system	system	NN
cord-330553-sukrjl22	63	25	as	as	IN
cord-330553-sukrjl22	63	26	seen	see	VBN
cord-330553-sukrjl22	63	27	in	in	IN
cord-330553-sukrjl22	63	28	the	the	DT
cord-330553-sukrjl22	63	29	ex	ex	FW
cord-330553-sukrjl22	63	30	vivo	vivo	NN
cord-330553-sukrjl22	63	31	slice	slice	NN
cord-330553-sukrjl22	63	32	culture	culture	NN
cord-330553-sukrjl22	63	33	model	model	NN
cord-330553-sukrjl22	63	34	.	.	.
cord-330553-sukrjl22	64	1	Activation	activation	NN
cord-330553-sukrjl22	64	2	of	of	IN
cord-330553-sukrjl22	64	3	the	the	DT
cord-330553-sukrjl22	64	4	microglia	microglia	NN
cord-330553-sukrjl22	64	5	is	be	VBZ
cord-330553-sukrjl22	64	6	characterized	characterize	VBN
cord-330553-sukrjl22	64	7	by	by	IN
cord-330553-sukrjl22	64	8	morphological	morphological	JJ
cord-330553-sukrjl22	64	9	changes	change	NNS
cord-330553-sukrjl22	64	10	and	and	CC
cord-330553-sukrjl22	64	11	is	be	VBZ
cord-330553-sukrjl22	64	12	associated	associate	VBN
cord-330553-sukrjl22	64	13	with	with	IN
cord-330553-sukrjl22	64	14	the	the	DT
cord-330553-sukrjl22	64	15	increased	increase	VBN
cord-330553-sukrjl22	64	16	production	production	NN
cord-330553-sukrjl22	64	17	of	of	IN
cord-330553-sukrjl22	64	18	inflammatory	inflammatory	JJ
cord-330553-sukrjl22	64	19	cytokines	cytokine	NNS
cord-330553-sukrjl22	64	20	/	/	SYM
cord-330553-sukrjl22	64	21	chemokines	chemokine	NNS
cord-330553-sukrjl22	64	22	.	.	.
cord-330553-sukrjl22	65	1	Based	base	VBN
cord-330553-sukrjl22	65	2	on	on	IN
cord-330553-sukrjl22	65	3	the	the	DT
cord-330553-sukrjl22	65	4	evidence	evidence	NN
cord-330553-sukrjl22	65	5	presented	present	VBN
cord-330553-sukrjl22	65	6	above	above	RB
cord-330553-sukrjl22	65	7	,	,	,
cord-330553-sukrjl22	65	8	it	-PRON-	PRP
cord-330553-sukrjl22	65	9	can	can	MD
cord-330553-sukrjl22	65	10	be	be	VB
cord-330553-sukrjl22	65	11	concluded	conclude	VBN
cord-330553-sukrjl22	65	12	that	that	IN
cord-330553-sukrjl22	65	13	microglia	microglia	NNP
cord-330553-sukrjl22	65	14	become	become	VBP
cord-330553-sukrjl22	65	15	activated	activate	VBN
cord-330553-sukrjl22	65	16	following	follow	VBG
cord-330553-sukrjl22	65	17	infection	infection	NN
cord-330553-sukrjl22	65	18	of	of	IN
cord-330553-sukrjl22	65	19	the	the	DT
cord-330553-sukrjl22	65	20	CNS	CNS	NNP
cord-330553-sukrjl22	65	21	with	with	IN
cord-330553-sukrjl22	65	22	WNV	WNV	NNP
cord-330553-sukrjl22	65	23	.	.	.
cord-330553-sukrjl22	66	1	These	these	DT
cord-330553-sukrjl22	66	2	activated	activate	VBN
cord-330553-sukrjl22	66	3	microglia	microglia	NNS
cord-330553-sukrjl22	66	4	can	can	MD
cord-330553-sukrjl22	66	5	initiate	initiate	VB
cord-330553-sukrjl22	66	6	an	an	DT
cord-330553-sukrjl22	66	7	immune	immune	JJ
cord-330553-sukrjl22	66	8	response	response	NN
cord-330553-sukrjl22	66	9	that	that	WDT
cord-330553-sukrjl22	66	10	is	be	VBZ
cord-330553-sukrjl22	66	11	intrinsic	intrinsic	JJ
cord-330553-sukrjl22	66	12	to	to	IN
cord-330553-sukrjl22	66	13	the	the	DT
cord-330553-sukrjl22	66	14	CNS	CNS	NNP
cord-330553-sukrjl22	66	15	and	and	CC
cord-330553-sukrjl22	66	16	does	do	VBZ
cord-330553-sukrjl22	66	17	not	not	RB
cord-330553-sukrjl22	66	18	require	require	VB
cord-330553-sukrjl22	66	19	input	input	NN
cord-330553-sukrjl22	66	20	from	from	IN
cord-330553-sukrjl22	66	21	the	the	DT
cord-330553-sukrjl22	66	22	peripheral	peripheral	JJ
cord-330553-sukrjl22	66	23	immune	immune	JJ
cord-330553-sukrjl22	66	24	system	system	NN
cord-330553-sukrjl22	66	25	as	as	IN
cord-330553-sukrjl22	66	26	seen	see	VBN
cord-330553-sukrjl22	66	27	in	in	IN
cord-330553-sukrjl22	66	28	the	the	DT
cord-330553-sukrjl22	66	29	ex	ex	FW
cord-330553-sukrjl22	66	30	vivo	vivo	NN
cord-330553-sukrjl22	66	31	slice	slice	NN
cord-330553-sukrjl22	66	32	culture	culture	NN
cord-330553-sukrjl22	66	33	model	model	NN
cord-330553-sukrjl22	66	34	.	.	.
cord-330553-sukrjl22	67	1	Activation	activation	NN
cord-330553-sukrjl22	67	2	of	of	IN
cord-330553-sukrjl22	67	3	the	the	DT
cord-330553-sukrjl22	67	4	microglia	microglia	NN
cord-330553-sukrjl22	67	5	is	be	VBZ
cord-330553-sukrjl22	67	6	characterized	characterize	VBN
cord-330553-sukrjl22	67	7	by	by	IN
cord-330553-sukrjl22	67	8	morphological	morphological	JJ
cord-330553-sukrjl22	67	9	changes	change	NNS
cord-330553-sukrjl22	67	10	and	and	CC
cord-330553-sukrjl22	67	11	is	be	VBZ
cord-330553-sukrjl22	67	12	associated	associate	VBN
cord-330553-sukrjl22	67	13	with	with	IN
cord-330553-sukrjl22	67	14	the	the	DT
cord-330553-sukrjl22	67	15	increased	increase	VBN
cord-330553-sukrjl22	67	16	production	production	NN
cord-330553-sukrjl22	67	17	of	of	IN
cord-330553-sukrjl22	67	18	inflammatory	inflammatory	JJ
cord-330553-sukrjl22	67	19	cytokines	cytokine	NNS
cord-330553-sukrjl22	67	20	/	/	SYM
cord-330553-sukrjl22	67	21	chemokines	chemokine	NNS
cord-330553-sukrjl22	67	22	.	.	.
cord-330553-sukrjl22	68	1	Toll	toll	NN
cord-330553-sukrjl22	68	2	-	-	HYPH
cord-330553-sukrjl22	68	3	Like	like	JJ
cord-330553-sukrjl22	68	4	Receptors	receptor	NNS
cord-330553-sukrjl22	68	5	(	(	-LRB-
cord-330553-sukrjl22	68	6	TLRs	TLRs	NNP
cord-330553-sukrjl22	68	7	)	)	-RRB-
cord-330553-sukrjl22	68	8	are	be	VBP
cord-330553-sukrjl22	68	9	membrane	membrane	NN
cord-330553-sukrjl22	68	10	spanning	span	VBG
cord-330553-sukrjl22	68	11	receptors	receptor	NNS
cord-330553-sukrjl22	68	12	commonly	commonly	RB
cord-330553-sukrjl22	68	13	expressed	express	VBN
cord-330553-sukrjl22	68	14	by	by	IN
cord-330553-sukrjl22	68	15	cells	cell	NNS
cord-330553-sukrjl22	68	16	such	such	JJ
cord-330553-sukrjl22	68	17	as	as	IN
cord-330553-sukrjl22	68	18	macrophages	macrophage	NNS
cord-330553-sukrjl22	68	19	,	,	,
cord-330553-sukrjl22	68	20	dendritic	dendritic	JJ
cord-330553-sukrjl22	68	21	cells	cell	NNS
cord-330553-sukrjl22	68	22	,	,	,
cord-330553-sukrjl22	68	23	and	and	CC
cord-330553-sukrjl22	68	24	microglia	microglia	NN
cord-330553-sukrjl22	68	25	,	,	,
cord-330553-sukrjl22	68	26	which	which	WDT
cord-330553-sukrjl22	68	27	monitor	monitor	VBP
cord-330553-sukrjl22	68	28	the	the	DT
cord-330553-sukrjl22	68	29	body	body	NN
cord-330553-sukrjl22	68	30	for	for	IN
cord-330553-sukrjl22	68	31	signs	sign	NNS
cord-330553-sukrjl22	68	32	of	of	IN
cord-330553-sukrjl22	68	33	infection	infection	NN
cord-330553-sukrjl22	68	34	.	.	.
cord-330553-sukrjl22	69	1	They	-PRON-	PRP
cord-330553-sukrjl22	69	2	play	play	VBP
cord-330553-sukrjl22	69	3	key	key	JJ
cord-330553-sukrjl22	69	4	roles	role	NNS
cord-330553-sukrjl22	69	5	in	in	IN
cord-330553-sukrjl22	69	6	the	the	DT
cord-330553-sukrjl22	69	7	innate	innate	JJ
cord-330553-sukrjl22	69	8	immune	immune	JJ
cord-330553-sukrjl22	69	9	system	system	NN
cord-330553-sukrjl22	69	10	[	[	-LRB-
cord-330553-sukrjl22	69	11	61	61	CD
cord-330553-sukrjl22	69	12	]	]	-RRB-
cord-330553-sukrjl22	69	13	and	and	CC
cord-330553-sukrjl22	69	14	have	have	VBP
cord-330553-sukrjl22	69	15	the	the	DT
cord-330553-sukrjl22	69	16	ability	ability	NN
cord-330553-sukrjl22	69	17	to	to	TO
cord-330553-sukrjl22	69	18	recognize	recognize	VB
cord-330553-sukrjl22	69	19	structurally	structurally	RB
cord-330553-sukrjl22	69	20	conserved	conserve	VBN
cord-330553-sukrjl22	69	21	pathogen	pathogen	NN
cord-330553-sukrjl22	69	22	-	-	HYPH
cord-330553-sukrjl22	69	23	associated	associate	VBN
cord-330553-sukrjl22	69	24	molecular	molecular	JJ
cord-330553-sukrjl22	69	25	patterns	pattern	NNS
cord-330553-sukrjl22	69	26	(	(	-LRB-
cord-330553-sukrjl22	69	27	PAMPS	PAMPS	NNP
cord-330553-sukrjl22	69	28	)	)	-RRB-
cord-330553-sukrjl22	69	29	present	present	JJ
cord-330553-sukrjl22	69	30	on	on	IN
cord-330553-sukrjl22	69	31	pathogens	pathogen	NNS
cord-330553-sukrjl22	69	32	[	[	-LRB-
cord-330553-sukrjl22	69	33	61	61	CD
cord-330553-sukrjl22	69	34	]	]	-RRB-
cord-330553-sukrjl22	69	35	[	[	-LRB-
cord-330553-sukrjl22	69	36	62	62	CD
cord-330553-sukrjl22	69	37	]	]	-RRB-
cord-330553-sukrjl22	69	38	[	[	-LRB-
cord-330553-sukrjl22	69	39	63	63	CD
cord-330553-sukrjl22	69	40	]	]	-RRB-
cord-330553-sukrjl22	69	41	.	.	.
cord-330553-sukrjl22	70	1	Microglial	microglial	JJ
cord-330553-sukrjl22	70	2	expression	expression	NN
cord-330553-sukrjl22	70	3	of	of	IN
cord-330553-sukrjl22	70	4	TLR3	TLR3	NNP
cord-330553-sukrjl22	70	5	,	,	,
cord-330553-sukrjl22	70	6	which	which	WDT
cord-330553-sukrjl22	70	7	recognizes	recognize	VBZ
cord-330553-sukrjl22	70	8	double	double	RB
cord-330553-sukrjl22	70	9	-	-	HYPH
cord-330553-sukrjl22	70	10	stranded	strand	VBN
cord-330553-sukrjl22	70	11	viral	viral	JJ
cord-330553-sukrjl22	70	12	RNA	RNA	NNP
cord-330553-sukrjl22	70	13	,	,	,
cord-330553-sukrjl22	70	14	is	be	VBZ
cord-330553-sukrjl22	70	15	thought	think	VBN
cord-330553-sukrjl22	70	16	to	to	TO
cord-330553-sukrjl22	70	17	play	play	VB
cord-330553-sukrjl22	70	18	an	an	DT
cord-330553-sukrjl22	70	19	important	important	JJ
cord-330553-sukrjl22	70	20	role	role	NN
cord-330553-sukrjl22	70	21	in	in	IN
cord-330553-sukrjl22	70	22	the	the	DT
cord-330553-sukrjl22	70	23	detection	detection	NN
cord-330553-sukrjl22	70	24	of	of	IN
cord-330553-sukrjl22	70	25	viruses	virus	NNS
cord-330553-sukrjl22	70	26	,	,	,
cord-330553-sukrjl22	70	27	including	include	VBG
cord-330553-sukrjl22	70	28	WNV	WNV	NNP
cord-330553-sukrjl22	70	29	,	,	,
cord-330553-sukrjl22	70	30	in	in	IN
cord-330553-sukrjl22	70	31	the	the	DT
cord-330553-sukrjl22	70	32	CNS	CNS	NNP
cord-330553-sukrjl22	70	33	[	[	-LRB-
cord-330553-sukrjl22	70	34	64	64	CD
cord-330553-sukrjl22	70	35	]	]	-RRB-
cord-330553-sukrjl22	70	36	.	.	.
cord-330553-sukrjl22	71	1	Several	several	JJ
cord-330553-sukrjl22	71	2	studies	study	NNS
cord-330553-sukrjl22	71	3	have	have	VBP
cord-330553-sukrjl22	71	4	shown	show	VBN
cord-330553-sukrjl22	71	5	that	that	IN
cord-330553-sukrjl22	71	6	TLR3	TLR3	NNP
cord-330553-sukrjl22	71	7	signaling	signaling	NN
cord-330553-sukrjl22	71	8	plays	play	VBZ
cord-330553-sukrjl22	71	9	a	a	DT
cord-330553-sukrjl22	71	10	protective	protective	JJ
cord-330553-sukrjl22	71	11	role	role	NN
cord-330553-sukrjl22	71	12	in	in	IN
cord-330553-sukrjl22	71	13	preventing	prevent	VBG
cord-330553-sukrjl22	71	14	lethal	lethal	JJ
cord-330553-sukrjl22	71	15	WNV	WNV	NNP
cord-330553-sukrjl22	71	16	encephalitis	encephalitis	JJ
cord-330553-sukrjl22	71	17	[	[	-LRB-
cord-330553-sukrjl22	71	18	54	54	CD
cord-330553-sukrjl22	71	19	,	,	,
cord-330553-sukrjl22	71	20	65	65	CD
cord-330553-sukrjl22	71	21	,	,	,
cord-330553-sukrjl22	71	22	66	66	CD
cord-330553-sukrjl22	71	23	]	]	-RRB-
cord-330553-sukrjl22	71	24	.	.	.
cord-330553-sukrjl22	72	1	For	for	IN
cord-330553-sukrjl22	72	2	example	example	NN
cord-330553-sukrjl22	72	3	,	,	,
cord-330553-sukrjl22	72	4	mice	mouse	NNS
cord-330553-sukrjl22	72	5	deficient	deficient	JJ
cord-330553-sukrjl22	72	6	in	in	IN
cord-330553-sukrjl22	72	7	the	the	DT
cord-330553-sukrjl22	72	8	expression	expression	NN
cord-330553-sukrjl22	72	9	of	of	IN
cord-330553-sukrjl22	72	10	TLR3	TLR3	NNP
cord-330553-sukrjl22	72	11	[	[	-LRB-
cord-330553-sukrjl22	72	12	63	63	CD
cord-330553-sukrjl22	72	13	,	,	,
cord-330553-sukrjl22	72	14	64	64	CD
cord-330553-sukrjl22	72	15	]	]	-RRB-
cord-330553-sukrjl22	72	16	and	and	CC
cord-330553-sukrjl22	72	17	Myeloid	Myeloid	NNP
cord-330553-sukrjl22	72	18	Differentiation	Differentiation	NNP
cord-330553-sukrjl22	72	19	Primary	primary	JJ
cord-330553-sukrjl22	72	20	Response	Response	NNP
cord-330553-sukrjl22	72	21	88	88	CD
cord-330553-sukrjl22	72	22	(	(	-LRB-
cord-330553-sukrjl22	72	23	MyD88	MyD88	NNP
cord-330553-sukrjl22	72	24	)	)	-RRB-
cord-330553-sukrjl22	72	25	,	,	,
cord-330553-sukrjl22	72	26	which	which	WDT
cord-330553-sukrjl22	72	27	functions	function	VBZ
cord-330553-sukrjl22	72	28	downstream	downstream	RB
cord-330553-sukrjl22	72	29	of	of	IN
cord-330553-sukrjl22	72	30	TLR3	TLR3	NNP
cord-330553-sukrjl22	72	31	[	[	-LRB-
cord-330553-sukrjl22	72	32	54	54	CD
cord-330553-sukrjl22	72	33	]	]	-RRB-
cord-330553-sukrjl22	72	34	,	,	,
cord-330553-sukrjl22	72	35	show	show	VBP
cord-330553-sukrjl22	72	36	increased	increase	VBN
cord-330553-sukrjl22	72	37	susceptibility	susceptibility	NN
cord-330553-sukrjl22	72	38	to	to	IN
cord-330553-sukrjl22	72	39	WNV	WNV	NNP
cord-330553-sukrjl22	72	40	that	that	WDT
cord-330553-sukrjl22	72	41	is	be	VBZ
cord-330553-sukrjl22	72	42	associated	associate	VBN
cord-330553-sukrjl22	72	43	with	with	IN
cord-330553-sukrjl22	72	44	higher	high	JJR
cord-330553-sukrjl22	72	45	viral	viral	JJ
cord-330553-sukrjl22	72	46	loads	load	NNS
cord-330553-sukrjl22	72	47	in	in	IN
cord-330553-sukrjl22	72	48	the	the	DT
cord-330553-sukrjl22	72	49	brain	brain	NN
cord-330553-sukrjl22	72	50	and	and	CC
cord-330553-sukrjl22	72	51	increased	increase	VBN
cord-330553-sukrjl22	72	52	expression	expression	NN
cord-330553-sukrjl22	72	53	of	of	IN
cord-330553-sukrjl22	72	54	inflammatory	inflammatory	JJ
cord-330553-sukrjl22	72	55	cytokines	cytokine	NNS
cord-330553-sukrjl22	72	56	.	.	.
cord-330553-sukrjl22	73	1	While	while	IN
cord-330553-sukrjl22	73	2	these	these	DT
cord-330553-sukrjl22	73	3	studies	study	NNS
cord-330553-sukrjl22	73	4	present	present	VBP
cord-330553-sukrjl22	73	5	evidence	evidence	NN
cord-330553-sukrjl22	73	6	for	for	IN
cord-330553-sukrjl22	73	7	a	a	DT
cord-330553-sukrjl22	73	8	protective	protective	JJ
cord-330553-sukrjl22	73	9	effect	effect	NN
cord-330553-sukrjl22	73	10	of	of	IN
cord-330553-sukrjl22	73	11	TLR3	TLR3	NNP
cord-330553-sukrjl22	73	12	following	follow	VBG
cord-330553-sukrjl22	73	13	WNV	WNV	NNP
cord-330553-sukrjl22	73	14	infection	infection	NN
cord-330553-sukrjl22	73	15	,	,	,
cord-330553-sukrjl22	73	16	an	an	DT
cord-330553-sukrjl22	73	17	earlier	early	JJR
cord-330553-sukrjl22	73	18	study	study	NN
cord-330553-sukrjl22	73	19	showed	show	VBD
cord-330553-sukrjl22	73	20	increased	increase	VBN
cord-330553-sukrjl22	73	21	survival	survival	NN
cord-330553-sukrjl22	73	22	from	from	IN
cord-330553-sukrjl22	73	23	WNV	WNV	NNP
cord-330553-sukrjl22	73	24	infections	infection	NNS
cord-330553-sukrjl22	73	25	in	in	IN
cord-330553-sukrjl22	73	26	TLR3-deficient	tlr3-deficient	NN
cord-330553-sukrjl22	73	27	mice	mouse	NNS
cord-330553-sukrjl22	73	28	[	[	-LRB-
cord-330553-sukrjl22	73	29	65	65	CD
cord-330553-sukrjl22	73	30	]	]	-RRB-
cord-330553-sukrjl22	73	31	.	.	.
cord-330553-sukrjl22	74	1	In	in	IN
cord-330553-sukrjl22	74	2	this	this	DT
cord-330553-sukrjl22	74	3	study	study	NN
cord-330553-sukrjl22	74	4	,	,	,
cord-330553-sukrjl22	74	5	TLR3-deficient	tlr3-deficient	NN
cord-330553-sukrjl22	74	6	mice	mouse	NNS
cord-330553-sukrjl22	74	7	were	be	VBD
cord-330553-sukrjl22	74	8	more	more	RBR
cord-330553-sukrjl22	74	9	resistant	resistant	JJ
cord-330553-sukrjl22	74	10	to	to	IN
cord-330553-sukrjl22	74	11	lethal	lethal	JJ
cord-330553-sukrjl22	74	12	WNV	WNV	NNP
cord-330553-sukrjl22	74	13	infection	infection	NN
cord-330553-sukrjl22	74	14	and	and	CC
cord-330553-sukrjl22	74	15	showed	show	VBD
cord-330553-sukrjl22	74	16	impaired	impaired	JJ
cord-330553-sukrjl22	74	17	cytokine	cytokine	NN
cord-330553-sukrjl22	74	18	production	production	NN
cord-330553-sukrjl22	74	19	along	along	IN
cord-330553-sukrjl22	74	20	with	with	IN
cord-330553-sukrjl22	74	21	enhanced	enhance	VBN
cord-330553-sukrjl22	74	22	viral	viral	JJ
cord-330553-sukrjl22	74	23	load	load	NN
cord-330553-sukrjl22	74	24	in	in	IN
cord-330553-sukrjl22	74	25	the	the	DT
cord-330553-sukrjl22	74	26	periphery	periphery	NN
cord-330553-sukrjl22	74	27	.	.	.
cord-330553-sukrjl22	75	1	However	however	RB
cord-330553-sukrjl22	75	2	,	,	,
cord-330553-sukrjl22	75	3	in	in	IN
cord-330553-sukrjl22	75	4	the	the	DT
cord-330553-sukrjl22	75	5	brain	brain	NN
cord-330553-sukrjl22	75	6	,	,	,
cord-330553-sukrjl22	75	7	viral	viral	JJ
cord-330553-sukrjl22	75	8	load	load	NN
cord-330553-sukrjl22	75	9	,	,	,
cord-330553-sukrjl22	75	10	inflammatory	inflammatory	JJ
cord-330553-sukrjl22	75	11	responses	response	NNS
cord-330553-sukrjl22	75	12	and	and	CC
cord-330553-sukrjl22	75	13	neuropathology	neuropathology	NN
cord-330553-sukrjl22	75	14	were	be	VBD
cord-330553-sukrjl22	75	15	reduced	reduce	VBN
cord-330553-sukrjl22	75	16	compared	compare	VBN
cord-330553-sukrjl22	75	17	to	to	IN
cord-330553-sukrjl22	75	18	wild	wild	JJ
cord-330553-sukrjl22	75	19	-	-	HYPH
cord-330553-sukrjl22	75	20	type	type	NN
cord-330553-sukrjl22	75	21	,	,	,
cord-330553-sukrjl22	75	22	indicating	indicate	VBG
cord-330553-sukrjl22	75	23	TLR3	TLR3	NNP
cord-330553-sukrjl22	75	24	may	may	MD
cord-330553-sukrjl22	75	25	mediate	mediate	VB
cord-330553-sukrjl22	75	26	entry	entry	NN
cord-330553-sukrjl22	75	27	of	of	IN
cord-330553-sukrjl22	75	28	WNV	WNV	NNP
cord-330553-sukrjl22	75	29	into	into	IN
cord-330553-sukrjl22	75	30	the	the	DT
cord-330553-sukrjl22	75	31	brain	brain	NN
cord-330553-sukrjl22	75	32	[	[	-LRB-
cord-330553-sukrjl22	75	33	67	67	CD
cord-330553-sukrjl22	75	34	]	]	-RRB-
cord-330553-sukrjl22	75	35	.	.	.
cord-330553-sukrjl22	76	1	It	-PRON-	PRP
cord-330553-sukrjl22	76	2	has	have	VBZ
cord-330553-sukrjl22	76	3	been	be	VBN
cord-330553-sukrjl22	76	4	suggested	suggest	VBN
cord-330553-sukrjl22	76	5	that	that	IN
cord-330553-sukrjl22	76	6	the	the	DT
cord-330553-sukrjl22	76	7	difference	difference	NN
cord-330553-sukrjl22	76	8	in	in	IN
cord-330553-sukrjl22	76	9	outcome	outcome	NN
cord-330553-sukrjl22	76	10	seen	see	VBN
cord-330553-sukrjl22	76	11	in	in	IN
cord-330553-sukrjl22	76	12	TLR3-deficient	tlr3-deficient	NN
cord-330553-sukrjl22	76	13	mice	mouse	NNS
cord-330553-sukrjl22	76	14	could	could	MD
cord-330553-sukrjl22	76	15	be	be	VB
cord-330553-sukrjl22	76	16	explained	explain	VBN
cord-330553-sukrjl22	76	17	by	by	IN
cord-330553-sukrjl22	76	18	the	the	DT
cord-330553-sukrjl22	76	19	distinct	distinct	JJ
cord-330553-sukrjl22	76	20	route	route	NN
cord-330553-sukrjl22	76	21	of	of	IN
cord-330553-sukrjl22	76	22	inoculation	inoculation	NN
cord-330553-sukrjl22	76	23	(	(	-LRB-
cord-330553-sukrjl22	76	24	subcutaneous	subcutaneous	JJ
cord-330553-sukrjl22	76	25	versus	versus	IN
cord-330553-sukrjl22	76	26	intraperitoneal	intraperitoneal	JJ
cord-330553-sukrjl22	76	27	)	)	-RRB-
cord-330553-sukrjl22	76	28	,	,	,
cord-330553-sukrjl22	76	29	passage	passage	NN
cord-330553-sukrjl22	76	30	history	history	NN
cord-330553-sukrjl22	76	31	of	of	IN
cord-330553-sukrjl22	76	32	the	the	DT
cord-330553-sukrjl22	76	33	virus	virus	NN
cord-330553-sukrjl22	76	34	(	(	-LRB-
cord-330553-sukrjl22	76	35	mammalian	mammalian	JJ
cord-330553-sukrjl22	76	36	Vero	Vero	NNP
cord-330553-sukrjl22	76	37	cell	cell	NN
cord-330553-sukrjl22	76	38	versus	versus	IN
cord-330553-sukrjl22	76	39	insect	insect	NN
cord-330553-sukrjl22	76	40	-	-	HYPH
cord-330553-sukrjl22	76	41	cell	cell	NN
cord-330553-sukrjl22	76	42	derived	derive	VBN
cord-330553-sukrjl22	76	43	)	)	-RRB-
cord-330553-sukrjl22	76	44	,	,	,
cord-330553-sukrjl22	76	45	and/or	and/or	CC
cord-330553-sukrjl22	76	46	the	the	DT
cord-330553-sukrjl22	76	47	virus	virus	NN
cord-330553-sukrjl22	76	48	dose	dose	VBD
cord-330553-sukrjl22	76	49	[	[	-LRB-
cord-330553-sukrjl22	76	50	63	63	CD
cord-330553-sukrjl22	76	51	]	]	-RRB-
cord-330553-sukrjl22	76	52	.	.	.
cord-330553-sukrjl22	77	1	More	More	JJR
cord-330553-sukrjl22	77	2	research	research	NN
cord-330553-sukrjl22	77	3	will	will	MD
cord-330553-sukrjl22	77	4	need	need	VB
cord-330553-sukrjl22	77	5	to	to	TO
cord-330553-sukrjl22	77	6	be	be	VB
cord-330553-sukrjl22	77	7	done	do	VBN
cord-330553-sukrjl22	77	8	to	to	TO
cord-330553-sukrjl22	77	9	achieve	achieve	VB
cord-330553-sukrjl22	77	10	a	a	DT
cord-330553-sukrjl22	77	11	full	full	JJ
cord-330553-sukrjl22	77	12	understanding	understanding	NN
cord-330553-sukrjl22	77	13	of	of	IN
cord-330553-sukrjl22	77	14	the	the	DT
cord-330553-sukrjl22	77	15	role	role	NN
cord-330553-sukrjl22	77	16	of	of	IN
cord-330553-sukrjl22	77	17	TLR3	TLR3	NNP
cord-330553-sukrjl22	77	18	signaling	signal	VBG
cord-330553-sukrjl22	77	19	in	in	IN
cord-330553-sukrjl22	77	20	WNV	WNV	NNP
cord-330553-sukrjl22	77	21	encephalitis	encephalitis	RB
cord-330553-sukrjl22	77	22	.	.	.
cord-330553-sukrjl22	78	1	Retinoic	Retinoic	NNP
cord-330553-sukrjl22	78	2	Acid	acid	NN
cord-330553-sukrjl22	78	3	Inducible	Inducible	NNP
cord-330553-sukrjl22	78	4	Gene	Gene	NNP
cord-330553-sukrjl22	78	5	I	i	CD
cord-330553-sukrjl22	78	6	(	(	-LRB-
cord-330553-sukrjl22	78	7	RIG	rig	NN
cord-330553-sukrjl22	78	8	-	-	:
cord-330553-sukrjl22	78	9	I	i	NN
cord-330553-sukrjl22	78	10	)	)	-RRB-
cord-330553-sukrjl22	78	11	and	and	CC
cord-330553-sukrjl22	78	12	Melanoma	Melanoma	NNP
cord-330553-sukrjl22	78	13	Differentiation	Differentiation	NNP
cord-330553-sukrjl22	78	14	Antigen	Antigen	NNP
cord-330553-sukrjl22	78	15	5	5	CD
cord-330553-sukrjl22	78	16	(	(	-LRB-
cord-330553-sukrjl22	78	17	MDA5	MDA5	NNP
cord-330553-sukrjl22	78	18	)	)	-RRB-
cord-330553-sukrjl22	78	19	are	be	VBP
cord-330553-sukrjl22	78	20	cytosolic	cytosolic	JJ
cord-330553-sukrjl22	78	21	pattern	pattern	NN
cord-330553-sukrjl22	78	22	recognition	recognition	NN
cord-330553-sukrjl22	78	23	receptors	receptor	NNS
cord-330553-sukrjl22	78	24	(	(	-LRB-
cord-330553-sukrjl22	78	25	PRRs	PRRs	NNP
cord-330553-sukrjl22	78	26	)	)	-RRB-
cord-330553-sukrjl22	78	27	,	,	,
cord-330553-sukrjl22	78	28	which	which	WDT
cord-330553-sukrjl22	78	29	recognize	recognize	VBP
cord-330553-sukrjl22	78	30	viral	viral	JJ
cord-330553-sukrjl22	78	31	RNA	RNA	NNP
cord-330553-sukrjl22	78	32	products	product	NNS
cord-330553-sukrjl22	78	33	,	,	,
cord-330553-sukrjl22	78	34	including	include	VBG
cord-330553-sukrjl22	78	35	WNV	WNV	NNP
cord-330553-sukrjl22	78	36	genetic	genetic	JJ
cord-330553-sukrjl22	78	37	material	material	NN
cord-330553-sukrjl22	78	38	,	,	,
cord-330553-sukrjl22	78	39	and	and	CC
cord-330553-sukrjl22	78	40	are	be	VBP
cord-330553-sukrjl22	78	41	critical	critical	JJ
cord-330553-sukrjl22	78	42	for	for	IN
cord-330553-sukrjl22	78	43	initiating	initiate	VBG
cord-330553-sukrjl22	78	44	an	an	DT
cord-330553-sukrjl22	78	45	innate	innate	JJ
cord-330553-sukrjl22	78	46	immune	immune	JJ
cord-330553-sukrjl22	78	47	defense	defense	NN
cord-330553-sukrjl22	78	48	[	[	-LRB-
cord-330553-sukrjl22	78	49	68	68	CD
cord-330553-sukrjl22	78	50	,	,	,
cord-330553-sukrjl22	78	51	69	69	CD
cord-330553-sukrjl22	78	52	]	]	-RRB-
cord-330553-sukrjl22	78	53	.	.	.
cord-330553-sukrjl22	79	1	Lack	lack	NN
cord-330553-sukrjl22	79	2	of	of	IN
cord-330553-sukrjl22	79	3	either	either	DT
cord-330553-sukrjl22	79	4	RIG	rig	NN
cord-330553-sukrjl22	79	5	-	-	:
cord-330553-sukrjl22	79	6	I	I	NNP
cord-330553-sukrjl22	79	7	or	or	CC
cord-330553-sukrjl22	79	8	MDA5	MDA5	NNP
cord-330553-sukrjl22	79	9	in	in	IN
cord-330553-sukrjl22	79	10	mice	mice	NN
cord-330553-sukrjl22	79	11	results	result	NNS
cord-330553-sukrjl22	79	12	in	in	IN
cord-330553-sukrjl22	79	13	decreased	decrease	VBN
cord-330553-sukrjl22	79	14	innate	innate	JJ
cord-330553-sukrjl22	79	15	immune	immune	JJ
cord-330553-sukrjl22	79	16	signaling	signaling	NN
cord-330553-sukrjl22	79	17	and	and	CC
cord-330553-sukrjl22	79	18	control	control	NN
cord-330553-sukrjl22	79	19	of	of	IN
cord-330553-sukrjl22	79	20	viral	viral	JJ
cord-330553-sukrjl22	79	21	growth	growth	NN
cord-330553-sukrjl22	79	22	.	.	.
cord-330553-sukrjl22	80	1	A	a	DT
cord-330553-sukrjl22	80	2	double	double	JJ
cord-330553-sukrjl22	80	3	knockout	knockout	NN
cord-330553-sukrjl22	80	4	of	of	IN
cord-330553-sukrjl22	80	5	both	both	DT
cord-330553-sukrjl22	80	6	receptors	receptor	NNS
cord-330553-sukrjl22	80	7	leads	lead	VBZ
cord-330553-sukrjl22	80	8	to	to	TO
cord-330553-sukrjl22	80	9	complete	complete	VB
cord-330553-sukrjl22	80	10	loss	loss	NN
cord-330553-sukrjl22	80	11	of	of	IN
cord-330553-sukrjl22	80	12	innate	innate	JJ
cord-330553-sukrjl22	80	13	immunity	immunity	NN
cord-330553-sukrjl22	80	14	gene	gene	NN
cord-330553-sukrjl22	80	15	function	function	NN
cord-330553-sukrjl22	80	16	in	in	IN
cord-330553-sukrjl22	80	17	WNV	WNV	NNP
cord-330553-sukrjl22	80	18	-	-	HYPH
cord-330553-sukrjl22	80	19	infected	infect	VBN
cord-330553-sukrjl22	80	20	cells	cell	NNS
cord-330553-sukrjl22	80	21	and	and	CC
cord-330553-sukrjl22	80	22	severe	severe	JJ
cord-330553-sukrjl22	80	23	disease	disease	NN
cord-330553-sukrjl22	80	24	in	in	IN
cord-330553-sukrjl22	80	25	mice	mouse	NNS
cord-330553-sukrjl22	80	26	[	[	-LRB-
cord-330553-sukrjl22	80	27	68	68	CD
cord-330553-sukrjl22	80	28	]	]	-RRB-
cord-330553-sukrjl22	80	29	.	.	.
cord-330553-sukrjl22	81	1	Microglia	Microglia	NNP
cord-330553-sukrjl22	81	2	constitutively	constitutively	RB
cord-330553-sukrjl22	81	3	express	express	VBP
cord-330553-sukrjl22	81	4	both	both	DT
cord-330553-sukrjl22	81	5	RIG	rig	NN
cord-330553-sukrjl22	81	6	-	-	:
cord-330553-sukrjl22	81	7	I	I	NNP
cord-330553-sukrjl22	81	8	and	and	CC
cord-330553-sukrjl22	81	9	MDA5	MDA5	NNP
cord-330553-sukrjl22	81	10	[	[	-LRB-
cord-330553-sukrjl22	81	11	70	70	CD
cord-330553-sukrjl22	81	12	]	]	-RRB-
cord-330553-sukrjl22	81	13	.	.	.
cord-330553-sukrjl22	82	1	The	the	DT
cord-330553-sukrjl22	82	2	downstream	downstream	JJ
cord-330553-sukrjl22	82	3	central	central	JJ
cord-330553-sukrjl22	82	4	adaptor	adaptor	NN
cord-330553-sukrjl22	82	5	molecule	molecule	NN
cord-330553-sukrjl22	82	6	mitochondrial	mitochondrial	JJ
cord-330553-sukrjl22	82	7	antiviral	antiviral	JJ
cord-330553-sukrjl22	82	8	-	-	HYPH
cord-330553-sukrjl22	82	9	signaling	signal	VBG
cord-330553-sukrjl22	82	10	protein	protein	NN
cord-330553-sukrjl22	82	11	(	(	-LRB-
cord-330553-sukrjl22	82	12	MAVS	MAVS	NNP
cord-330553-sukrjl22	82	13	)	)	-RRB-
cord-330553-sukrjl22	82	14	is	be	VBZ
cord-330553-sukrjl22	82	15	also	also	RB
cord-330553-sukrjl22	82	16	essential	essential	JJ
cord-330553-sukrjl22	82	17	for	for	IN
cord-330553-sukrjl22	82	18	control	control	NN
cord-330553-sukrjl22	82	19	of	of	IN
cord-330553-sukrjl22	82	20	WNV	WNV	NNP
cord-330553-sukrjl22	82	21	infections	infection	NNS
cord-330553-sukrjl22	82	22	.	.	.
cord-330553-sukrjl22	83	1	A	a	DT
cord-330553-sukrjl22	83	2	deficiency	deficiency	NN
cord-330553-sukrjl22	83	3	in	in	IN
cord-330553-sukrjl22	83	4	MAVS	MAVS	NNPS
cord-330553-sukrjl22	83	5	in	in	IN
cord-330553-sukrjl22	83	6	hematopoietic	hematopoietic	JJ
cord-330553-sukrjl22	83	7	cells	cell	NNS
cord-330553-sukrjl22	83	8	,	,	,
cord-330553-sukrjl22	83	9	such	such	JJ
cord-330553-sukrjl22	83	10	as	as	IN
cord-330553-sukrjl22	83	11	microglia	microglia	NN
cord-330553-sukrjl22	83	12	and	and	CC
cord-330553-sukrjl22	83	13	macrophages	macrophage	NNS
cord-330553-sukrjl22	83	14	,	,	,
cord-330553-sukrjl22	83	15	leads	lead	VBZ
cord-330553-sukrjl22	83	16	to	to	IN
cord-330553-sukrjl22	83	17	increased	increase	VBN
cord-330553-sukrjl22	83	18	mortality	mortality	NN
cord-330553-sukrjl22	83	19	in	in	IN
cord-330553-sukrjl22	83	20	mice	mouse	NNS
cord-330553-sukrjl22	83	21	infected	infect	VBN
cord-330553-sukrjl22	83	22	with	with	IN
cord-330553-sukrjl22	83	23	WNV	WNV	NNP
cord-330553-sukrjl22	83	24	[	[	-LRB-
cord-330553-sukrjl22	83	25	71	71	CD
cord-330553-sukrjl22	83	26	]	]	-RRB-
cord-330553-sukrjl22	83	27	.	.	.
cord-330553-sukrjl22	84	1	These	these	DT
cord-330553-sukrjl22	84	2	findings	finding	NNS
cord-330553-sukrjl22	84	3	indicate	indicate	VBP
cord-330553-sukrjl22	84	4	the	the	DT
cord-330553-sukrjl22	84	5	importance	importance	NN
cord-330553-sukrjl22	84	6	of	of	IN
cord-330553-sukrjl22	84	7	the	the	DT
cord-330553-sukrjl22	84	8	MAVS	MAVS	NNPS
cord-330553-sukrjl22	84	9	signaling	signal	VBG
cord-330553-sukrjl22	84	10	pathway	pathway	NN
cord-330553-sukrjl22	84	11	in	in	IN
cord-330553-sukrjl22	84	12	the	the	DT
cord-330553-sukrjl22	84	13	microglial	microglial	JJ
cord-330553-sukrjl22	84	14	response	response	NN
cord-330553-sukrjl22	84	15	to	to	IN
cord-330553-sukrjl22	84	16	WNV	WNV	NNP
cord-330553-sukrjl22	84	17	particles	particle	NNS
cord-330553-sukrjl22	84	18	within	within	IN
cord-330553-sukrjl22	84	19	the	the	DT
cord-330553-sukrjl22	84	20	CNS	CNS	NNP
cord-330553-sukrjl22	84	21	.	.	.
cord-330553-sukrjl22	85	1	As	as	IN
cord-330553-sukrjl22	85	2	documented	document	VBN
cord-330553-sukrjl22	85	3	above	above	RB
cord-330553-sukrjl22	85	4	,	,	,
cord-330553-sukrjl22	85	5	microglia	microglia	NNS
cord-330553-sukrjl22	85	6	recognize	recognize	VBP
cord-330553-sukrjl22	85	7	and	and	CC
cord-330553-sukrjl22	85	8	become	become	VBP
cord-330553-sukrjl22	85	9	activated	activate	VBN
cord-330553-sukrjl22	85	10	in	in	IN
cord-330553-sukrjl22	85	11	response	response	NN
cord-330553-sukrjl22	85	12	to	to	IN
cord-330553-sukrjl22	85	13	WNV	WNV	NNP
cord-330553-sukrjl22	85	14	infection	infection	NN
cord-330553-sukrjl22	85	15	.	.	.
cord-330553-sukrjl22	86	1	However	however	RB
cord-330553-sukrjl22	86	2	,	,	,
cord-330553-sukrjl22	86	3	it	-PRON-	PRP
cord-330553-sukrjl22	86	4	remains	remain	VBZ
cord-330553-sukrjl22	86	5	unclear	unclear	JJ
cord-330553-sukrjl22	86	6	if	if	IN
cord-330553-sukrjl22	86	7	this	this	DT
cord-330553-sukrjl22	86	8	process	process	NN
cord-330553-sukrjl22	86	9	is	be	VBZ
cord-330553-sukrjl22	86	10	essential	essential	JJ
cord-330553-sukrjl22	86	11	to	to	IN
cord-330553-sukrjl22	86	12	effective	effective	JJ
cord-330553-sukrjl22	86	13	host	host	NN
cord-330553-sukrjl22	86	14	protection	protection	NN
cord-330553-sukrjl22	86	15	against	against	IN
cord-330553-sukrjl22	86	16	WNV	WNV	NNP
cord-330553-sukrjl22	86	17	or	or	CC
cord-330553-sukrjl22	86	18	whether	whether	IN
cord-330553-sukrjl22	86	19	activated	activate	VBN
cord-330553-sukrjl22	86	20	microglia	microglia	NNS
cord-330553-sukrjl22	86	21	contribute	contribute	VBP
cord-330553-sukrjl22	86	22	to	to	IN
cord-330553-sukrjl22	86	23	pathogenesis	pathogenesis	NN
cord-330553-sukrjl22	86	24	.	.	.
cord-330553-sukrjl22	87	1	For	for	IN
cord-330553-sukrjl22	87	2	example	example	NN
cord-330553-sukrjl22	87	3	,	,	,
cord-330553-sukrjl22	87	4	following	follow	VBG
cord-330553-sukrjl22	87	5	infection	infection	NN
cord-330553-sukrjl22	87	6	with	with	IN
cord-330553-sukrjl22	87	7	WNV	WNV	NNP
cord-330553-sukrjl22	87	8	,	,	,
cord-330553-sukrjl22	87	9	both	both	DT
cord-330553-sukrjl22	87	10	decreased	decrease	VBD
cord-330553-sukrjl22	87	11	[	[	-LRB-
cord-330553-sukrjl22	87	12	53	53	CD
cord-330553-sukrjl22	87	13	]	]	-RRB-
cord-330553-sukrjl22	87	14	and	and	CC
cord-330553-sukrjl22	87	15	increased	increase	VBD
cord-330553-sukrjl22	87	16	[	[	-LRB-
cord-330553-sukrjl22	87	17	54	54	CD
cord-330553-sukrjl22	87	18	,	,	,
cord-330553-sukrjl22	87	19	64	64	CD
cord-330553-sukrjl22	87	20	]	]	-RRB-
cord-330553-sukrjl22	87	21	microglial	microglial	JJ
cord-330553-sukrjl22	87	22	activation	activation	NN
cord-330553-sukrjl22	87	23	have	have	VBP
cord-330553-sukrjl22	87	24	been	be	VBN
cord-330553-sukrjl22	87	25	associated	associate	VBN
cord-330553-sukrjl22	87	26	with	with	IN
cord-330553-sukrjl22	87	27	increased	increase	VBN
cord-330553-sukrjl22	87	28	neuronal	neuronal	JJ
cord-330553-sukrjl22	87	29	death	death	NN
cord-330553-sukrjl22	87	30	and	and	CC
cord-330553-sukrjl22	87	31	susceptibility	susceptibility	NN
cord-330553-sukrjl22	87	32	to	to	IN
cord-330553-sukrjl22	87	33	disease	disease	NN
cord-330553-sukrjl22	87	34	.	.	.
cord-330553-sukrjl22	88	1	To	to	TO
cord-330553-sukrjl22	88	2	address	address	VB
cord-330553-sukrjl22	88	3	this	this	DT
cord-330553-sukrjl22	88	4	disparity	disparity	NN
cord-330553-sukrjl22	88	5	,	,	,
cord-330553-sukrjl22	88	6	the	the	DT
cord-330553-sukrjl22	88	7	effect	effect	NN
cord-330553-sukrjl22	88	8	of	of	IN
cord-330553-sukrjl22	88	9	WNV	WNV	NNP
cord-330553-sukrjl22	88	10	infection	infection	NN
cord-330553-sukrjl22	88	11	on	on	IN
cord-330553-sukrjl22	88	12	mice	mouse	NNS
cord-330553-sukrjl22	88	13	lacking	lack	VBG
cord-330553-sukrjl22	88	14	microglia	microglia	NNS
cord-330553-sukrjl22	88	15	has	have	VBZ
cord-330553-sukrjl22	88	16	been	be	VBN
cord-330553-sukrjl22	88	17	investigated	investigate	VBN
cord-330553-sukrjl22	88	18	.	.	.
cord-330553-sukrjl22	89	1	Mice	mouse	NNS
cord-330553-sukrjl22	89	2	deficient	deficient	JJ
cord-330553-sukrjl22	89	3	in	in	IN
cord-330553-sukrjl22	89	4	the	the	DT
cord-330553-sukrjl22	89	5	expression	expression	NN
cord-330553-sukrjl22	89	6	of	of	IN
cord-330553-sukrjl22	89	7	interleukin	interleukin	NN
cord-330553-sukrjl22	89	8	34	34	CD
cord-330553-sukrjl22	89	9	(	(	-LRB-
cord-330553-sukrjl22	89	10	IL-34	IL-34	NNP
cord-330553-sukrjl22	89	11	)	)	-RRB-
cord-330553-sukrjl22	89	12	,	,	,
cord-330553-sukrjl22	89	13	which	which	WDT
cord-330553-sukrjl22	89	14	lack	lack	VBP
cord-330553-sukrjl22	89	15	microglia	microglia	NNS
cord-330553-sukrjl22	89	16	but	but	CC
cord-330553-sukrjl22	89	17	retain	retain	VB
cord-330553-sukrjl22	89	18	bone	bone	NN
cord-330553-sukrjl22	89	19	marrow	marrow	NN
cord-330553-sukrjl22	89	20	-	-	HYPH
cord-330553-sukrjl22	89	21	derived	derive	VBN
cord-330553-sukrjl22	89	22	macrophages	macrophage	NNS
cord-330553-sukrjl22	89	23	,	,	,
cord-330553-sukrjl22	89	24	have	have	VBP
cord-330553-sukrjl22	89	25	increased	increase	VBN
cord-330553-sukrjl22	89	26	susceptibility	susceptibility	NN
cord-330553-sukrjl22	89	27	to	to	IN
cord-330553-sukrjl22	89	28	WNV	WNV	NNP
cord-330553-sukrjl22	89	29	,	,	,
cord-330553-sukrjl22	89	30	suggesting	suggest	VBG
cord-330553-sukrjl22	89	31	a	a	DT
cord-330553-sukrjl22	89	32	role	role	NN
cord-330553-sukrjl22	89	33	for	for	IN
cord-330553-sukrjl22	89	34	microglia	microglia	NNS
cord-330553-sukrjl22	89	35	in	in	IN
cord-330553-sukrjl22	89	36	antiviral	antiviral	JJ
cord-330553-sukrjl22	89	37	defense	defense	NN
cord-330553-sukrjl22	89	38	[	[	-LRB-
cord-330553-sukrjl22	89	39	72	72	CD
cord-330553-sukrjl22	89	40	]	]	-RRB-
cord-330553-sukrjl22	89	41	.	.	.
cord-330553-sukrjl22	90	1	In	in	IN
cord-330553-sukrjl22	90	2	addition	addition	NN
cord-330553-sukrjl22	90	3	,	,	,
cord-330553-sukrjl22	90	4	recent	recent	JJ
cord-330553-sukrjl22	90	5	studies	study	NNS
cord-330553-sukrjl22	90	6	performed	perform	VBN
cord-330553-sukrjl22	90	7	in	in	IN
cord-330553-sukrjl22	90	8	mice	mouse	NNS
cord-330553-sukrjl22	90	9	in	in	IN
cord-330553-sukrjl22	90	10	which	which	WDT
cord-330553-sukrjl22	90	11	microglia	microglia	NNS
cord-330553-sukrjl22	90	12	were	be	VBD
cord-330553-sukrjl22	90	13	depleted	deplete	VBN
cord-330553-sukrjl22	90	14	using	use	VBG
cord-330553-sukrjl22	90	15	Plexxicon	Plexxicon	NNP
cord-330553-sukrjl22	90	16	5622	5622	CD
cord-330553-sukrjl22	90	17	(	(	-LRB-
cord-330553-sukrjl22	90	18	PLX5622	PLX5622	NNP
cord-330553-sukrjl22	90	19	)	)	-RRB-
cord-330553-sukrjl22	90	20	,	,	,
cord-330553-sukrjl22	90	21	an	an	DT
cord-330553-sukrjl22	90	22	inhibitor	inhibitor	NN
cord-330553-sukrjl22	90	23	of	of	IN
cord-330553-sukrjl22	90	24	colony	colony	NN
cord-330553-sukrjl22	90	25	-	-	HYPH
cord-330553-sukrjl22	90	26	stimulating	stimulate	VBG
cord-330553-sukrjl22	90	27	factor	factor	NN
cord-330553-sukrjl22	90	28	1	1	CD
cord-330553-sukrjl22	90	29	receptor	receptor	NN
cord-330553-sukrjl22	90	30	(	(	-LRB-
cord-330553-sukrjl22	90	31	CSF1R	CSF1R	NNS
cord-330553-sukrjl22	90	32	)	)	-RRB-
cord-330553-sukrjl22	90	33	,	,	,
cord-330553-sukrjl22	90	34	demonstrated	demonstrate	VBD
cord-330553-sukrjl22	90	35	a	a	DT
cord-330553-sukrjl22	90	36	significant	significant	JJ
cord-330553-sukrjl22	90	37	increase	increase	NN
cord-330553-sukrjl22	90	38	in	in	IN
cord-330553-sukrjl22	90	39	susceptibility	susceptibility	NN
cord-330553-sukrjl22	90	40	to	to	IN
cord-330553-sukrjl22	90	41	WNV	WNV	NNP
cord-330553-sukrjl22	90	42	-	-	HYPH
cord-330553-sukrjl22	90	43	induced	induce	VBN
cord-330553-sukrjl22	90	44	CNS	CNS	NNP
cord-330553-sukrjl22	90	45	disease	disease	NN
cord-330553-sukrjl22	90	46	[	[	-LRB-
cord-330553-sukrjl22	90	47	60	60	CD
cord-330553-sukrjl22	90	48	]	]	-RRB-
cord-330553-sukrjl22	90	49	.	.	.
cord-330553-sukrjl22	91	1	Colony	colony	NN
cord-330553-sukrjl22	91	2	-	-	HYPH
cord-330553-sukrjl22	91	3	stimulating	stimulate	VBG
cord-330553-sukrjl22	91	4	factor	factor	NN
cord-330553-sukrjl22	91	5	1	1	CD
cord-330553-sukrjl22	91	6	is	be	VBZ
cord-330553-sukrjl22	91	7	critical	critical	JJ
cord-330553-sukrjl22	91	8	for	for	IN
cord-330553-sukrjl22	91	9	microglia	microglia	JJ
cord-330553-sukrjl22	91	10	survival	survival	NN
cord-330553-sukrjl22	91	11	[	[	-LRB-
cord-330553-sukrjl22	91	12	72	72	CD
cord-330553-sukrjl22	91	13	]	]	-RRB-
cord-330553-sukrjl22	91	14	[	[	-LRB-
cord-330553-sukrjl22	91	15	73	73	CD
cord-330553-sukrjl22	91	16	]	]	-RRB-
cord-330553-sukrjl22	91	17	[	[	-LRB-
cord-330553-sukrjl22	91	18	74	74	CD
cord-330553-sukrjl22	91	19	]	]	-RRB-
cord-330553-sukrjl22	91	20	,	,	,
cord-330553-sukrjl22	91	21	and	and	CC
cord-330553-sukrjl22	91	22	PLX5622	PLX5622	NNP
cord-330553-sukrjl22	91	23	has	have	VBZ
cord-330553-sukrjl22	91	24	been	be	VBN
cord-330553-sukrjl22	91	25	shown	show	VBN
cord-330553-sukrjl22	91	26	to	to	TO
cord-330553-sukrjl22	91	27	have	have	VB
cord-330553-sukrjl22	91	28	specificity	specificity	NN
cord-330553-sukrjl22	91	29	towards	towards	IN
cord-330553-sukrjl22	91	30	microglia	microglia	NNS
cord-330553-sukrjl22	91	31	without	without	IN
cord-330553-sukrjl22	91	32	affecting	affect	VBG
cord-330553-sukrjl22	91	33	other	other	JJ
cord-330553-sukrjl22	91	34	cell	cell	NN
cord-330553-sukrjl22	91	35	populations	population	NNS
cord-330553-sukrjl22	91	36	such	such	JJ
cord-330553-sukrjl22	91	37	as	as	IN
cord-330553-sukrjl22	91	38	brain	brain	NN
cord-330553-sukrjl22	91	39	-	-	HYPH
cord-330553-sukrjl22	91	40	specific	specific	JJ
cord-330553-sukrjl22	91	41	macrophages	macrophage	NNS
cord-330553-sukrjl22	91	42	,	,	,
cord-330553-sukrjl22	91	43	peripheral	peripheral	JJ
cord-330553-sukrjl22	91	44	macrophages	macrophage	NNS
cord-330553-sukrjl22	91	45	,	,	,
cord-330553-sukrjl22	91	46	or	or	CC
cord-330553-sukrjl22	91	47	lymphocytes	lymphocyte	NNS
cord-330553-sukrjl22	91	48	[	[	-LRB-
cord-330553-sukrjl22	91	49	49	49	CD
cord-330553-sukrjl22	91	50	,	,	,
cord-330553-sukrjl22	91	51	75	75	CD
cord-330553-sukrjl22	91	52	,	,	,
cord-330553-sukrjl22	91	53	76	76	CD
cord-330553-sukrjl22	91	54	]	]	-RRB-
cord-330553-sukrjl22	91	55	.	.	.
cord-330553-sukrjl22	92	1	Microglial	microglial	JJ
cord-330553-sukrjl22	92	2	depletion	depletion	NN
cord-330553-sukrjl22	92	3	using	use	VBG
cord-330553-sukrjl22	92	4	PLX5622	PLX5622	NNP
cord-330553-sukrjl22	92	5	does	do	VBZ
cord-330553-sukrjl22	92	6	not	not	RB
cord-330553-sukrjl22	92	7	alter	alter	VB
cord-330553-sukrjl22	92	8	brain	brain	NN
cord-330553-sukrjl22	92	9	size	size	NN
cord-330553-sukrjl22	92	10	,	,	,
cord-330553-sukrjl22	92	11	cognition	cognition	NN
cord-330553-sukrjl22	92	12	,	,	,
cord-330553-sukrjl22	92	13	or	or	CC
cord-330553-sukrjl22	92	14	motor	motor	NN
cord-330553-sukrjl22	92	15	function	function	NN
cord-330553-sukrjl22	92	16	in	in	IN
cord-330553-sukrjl22	92	17	mice	mouse	NNS
cord-330553-sukrjl22	92	18	[	[	-LRB-
cord-330553-sukrjl22	92	19	76	76	CD
cord-330553-sukrjl22	92	20	]	]	-RRB-
cord-330553-sukrjl22	92	21	.	.	.
cord-330553-sukrjl22	93	1	To	to	TO
cord-330553-sukrjl22	93	2	deplete	deplete	VB
cord-330553-sukrjl22	93	3	microglia	microglia	NNS
cord-330553-sukrjl22	93	4	,	,	,
cord-330553-sukrjl22	93	5	mice	mouse	NNS
cord-330553-sukrjl22	93	6	were	be	VBD
cord-330553-sukrjl22	93	7	fed	feed	VBN
cord-330553-sukrjl22	93	8	a	a	DT
cord-330553-sukrjl22	93	9	diet	diet	NN
cord-330553-sukrjl22	93	10	containing	contain	VBG
cord-330553-sukrjl22	93	11	PLX5622	PLX5622	NNP
cord-330553-sukrjl22	93	12	for	for	IN
cord-330553-sukrjl22	93	13	10	10	CD
cord-330553-sukrjl22	93	14	days	day	NNS
cord-330553-sukrjl22	93	15	resulting	result	VBG
cord-330553-sukrjl22	93	16	in	in	IN
cord-330553-sukrjl22	93	17	greater	great	JJR
cord-330553-sukrjl22	93	18	than	than	IN
cord-330553-sukrjl22	93	19	80	80	CD
cord-330553-sukrjl22	93	20	%	%	NN
cord-330553-sukrjl22	93	21	depletion	depletion	NN
cord-330553-sukrjl22	93	22	of	of	IN
cord-330553-sukrjl22	93	23	their	-PRON-	PRP$
cord-330553-sukrjl22	93	24	microglia	microglia	JJ
cord-330553-sukrjl22	93	25	population	population	NN
cord-330553-sukrjl22	93	26	throughout	throughout	IN
cord-330553-sukrjl22	93	27	the	the	DT
cord-330553-sukrjl22	93	28	brain	brain	NN
cord-330553-sukrjl22	93	29	when	when	WRB
cord-330553-sukrjl22	93	30	compared	compare	VBN
cord-330553-sukrjl22	93	31	to	to	IN
cord-330553-sukrjl22	93	32	mice	mouse	NNS
cord-330553-sukrjl22	93	33	fed	feed	VBD
cord-330553-sukrjl22	93	34	a	a	DT
cord-330553-sukrjl22	93	35	control	control	NN
cord-330553-sukrjl22	93	36	diet	diet	NN
cord-330553-sukrjl22	93	37	[	[	-LRB-
cord-330553-sukrjl22	93	38	60	60	CD
cord-330553-sukrjl22	93	39	]	]	-RRB-
cord-330553-sukrjl22	93	40	.	.	.
cord-330553-sukrjl22	94	1	Following	follow	VBG
cord-330553-sukrjl22	94	2	infection	infection	NN
cord-330553-sukrjl22	94	3	of	of	IN
cord-330553-sukrjl22	94	4	PLX5622-treated	PLX5622-treated	NNP
cord-330553-sukrjl22	94	5	mice	mouse	NNS
cord-330553-sukrjl22	94	6	with	with	IN
cord-330553-sukrjl22	94	7	WNV	WNV	NNP
cord-330553-sukrjl22	94	8	,	,	,
cord-330553-sukrjl22	94	9	brain	brain	NN
cord-330553-sukrjl22	94	10	titers	titer	NNS
cord-330553-sukrjl22	94	11	were	be	VBD
cord-330553-sukrjl22	94	12	significantly	significantly	RB
cord-330553-sukrjl22	94	13	(	(	-LRB-
cord-330553-sukrjl22	94	14	10	10	CD
cord-330553-sukrjl22	94	15	-	-	SYM
cord-330553-sukrjl22	94	16	100-fold	100-fold	CD
cord-330553-sukrjl22	94	17	)	)	-RRB-
cord-330553-sukrjl22	94	18	higher	high	JJR
cord-330553-sukrjl22	94	19	than	than	IN
cord-330553-sukrjl22	94	20	in	in	IN
cord-330553-sukrjl22	94	21	control	control	NN
cord-330553-sukrjl22	94	22	mice	mouse	NNS
cord-330553-sukrjl22	94	23	at	at	IN
cord-330553-sukrjl22	94	24	days	day	NNS
cord-330553-sukrjl22	94	25	6	6	CD
cord-330553-sukrjl22	94	26	,	,	,
cord-330553-sukrjl22	94	27	9	9	CD
cord-330553-sukrjl22	94	28	,	,	,
cord-330553-sukrjl22	94	29	and	and	CC
cord-330553-sukrjl22	94	30	10	10	CD
cord-330553-sukrjl22	94	31	post	post	NN
cord-330553-sukrjl22	94	32	infection	infection	NN
cord-330553-sukrjl22	94	33	.	.	.
cord-330553-sukrjl22	95	1	In	in	IN
cord-330553-sukrjl22	95	2	addition	addition	NN
cord-330553-sukrjl22	95	3	,	,	,
cord-330553-sukrjl22	95	4	mortality	mortality	NN
cord-330553-sukrjl22	95	5	dramatically	dramatically	RB
cord-330553-sukrjl22	95	6	increased	increase	VBD
cord-330553-sukrjl22	95	7	.	.	.
cord-330553-sukrjl22	96	1	Of	of	IN
cord-330553-sukrjl22	96	2	the	the	DT
cord-330553-sukrjl22	96	3	mice	mouse	NNS
cord-330553-sukrjl22	96	4	infected	infect	VBN
cord-330553-sukrjl22	96	5	with	with	IN
cord-330553-sukrjl22	96	6	WNV	WNV	NNP
cord-330553-sukrjl22	96	7	,	,	,
cord-330553-sukrjl22	96	8	100	100	CD
cord-330553-sukrjl22	96	9	%	%	NN
cord-330553-sukrjl22	96	10	of	of	IN
cord-330553-sukrjl22	96	11	PLX	PLX	NNP
cord-330553-sukrjl22	96	12	-	-	HYPH
cord-330553-sukrjl22	96	13	treated	treat	VBN
cord-330553-sukrjl22	96	14	microglia	microglia	NN
cord-330553-sukrjl22	96	15	-	-	HYPH
cord-330553-sukrjl22	96	16	depleted	deplete	VBN
cord-330553-sukrjl22	96	17	mice	mouse	NNS
cord-330553-sukrjl22	96	18	died	die	VBD
cord-330553-sukrjl22	96	19	compared	compare	VBN
cord-330553-sukrjl22	96	20	to	to	IN
cord-330553-sukrjl22	96	21	only	only	RB
cord-330553-sukrjl22	96	22	25	25	CD
cord-330553-sukrjl22	96	23	%	%	NN
cord-330553-sukrjl22	96	24	of	of	IN
cord-330553-sukrjl22	96	25	the	the	DT
cord-330553-sukrjl22	96	26	control	control	NN
cord-330553-sukrjl22	96	27	fed	feed	VBD
cord-330553-sukrjl22	96	28	mice	mouse	NNS
cord-330553-sukrjl22	96	29	[	[	-LRB-
cord-330553-sukrjl22	96	30	60	60	CD
cord-330553-sukrjl22	96	31	]	]	-RRB-
cord-330553-sukrjl22	96	32	.	.	.
cord-330553-sukrjl22	97	1	These	these	DT
cord-330553-sukrjl22	97	2	studies	study	NNS
cord-330553-sukrjl22	97	3	indicate	indicate	VBP
cord-330553-sukrjl22	97	4	that	that	IN
cord-330553-sukrjl22	97	5	microglia	microglia	NNS
cord-330553-sukrjl22	97	6	play	play	VBP
cord-330553-sukrjl22	97	7	a	a	DT
cord-330553-sukrjl22	97	8	critical	critical	JJ
cord-330553-sukrjl22	97	9	role	role	NN
cord-330553-sukrjl22	97	10	in	in	IN
cord-330553-sukrjl22	97	11	controlling	control	VBG
cord-330553-sukrjl22	97	12	WNV	WNV	NNP
cord-330553-sukrjl22	97	13	infection	infection	NN
cord-330553-sukrjl22	97	14	and	and	CC
cord-330553-sukrjl22	97	15	limiting	limit	VBG
cord-330553-sukrjl22	97	16	WNV	WNV	NNP
cord-330553-sukrjl22	97	17	-	-	HYPH
cord-330553-sukrjl22	97	18	induced	induce	VBN
cord-330553-sukrjl22	97	19	mortality	mortality	NN
cord-330553-sukrjl22	97	20	.	.	.
cord-330553-sukrjl22	98	1	Results	result	NNS
cord-330553-sukrjl22	98	2	in	in	IN
cord-330553-sukrjl22	98	3	WNV	WNV	NNP
cord-330553-sukrjl22	98	4	-	-	HYPH
cord-330553-sukrjl22	98	5	infected	infect	VBN
cord-330553-sukrjl22	98	6	PLX5622-treated	PLX5622-treated	NNP
cord-330553-sukrjl22	98	7	mice	mouse	NNS
cord-330553-sukrjl22	98	8	were	be	VBD
cord-330553-sukrjl22	98	9	remarkably	remarkably	RB
cord-330553-sukrjl22	98	10	similar	similar	JJ
cord-330553-sukrjl22	98	11	to	to	IN
cord-330553-sukrjl22	98	12	another	another	DT
cord-330553-sukrjl22	98	13	recent	recent	JJ
cord-330553-sukrjl22	98	14	study	study	NN
cord-330553-sukrjl22	98	15	,	,	,
cord-330553-sukrjl22	98	16	which	which	WDT
cord-330553-sukrjl22	98	17	found	find	VBD
cord-330553-sukrjl22	98	18	that	that	IN
cord-330553-sukrjl22	98	19	microglia	microglia	NNS
cord-330553-sukrjl22	98	20	are	be	VBP
cord-330553-sukrjl22	98	21	crucial	crucial	JJ
cord-330553-sukrjl22	98	22	for	for	IN
cord-330553-sukrjl22	98	23	protection	protection	NN
cord-330553-sukrjl22	98	24	of	of	IN
cord-330553-sukrjl22	98	25	mice	mouse	NNS
cord-330553-sukrjl22	98	26	from	from	IN
cord-330553-sukrjl22	98	27	neurotropic	neurotropic	NNP
cord-330553-sukrjl22	98	28	coronavirus	coronavirus	NN
cord-330553-sukrjl22	98	29	encephalitis	encephalitis	RB
cord-330553-sukrjl22	98	30	and	and	CC
cord-330553-sukrjl22	98	31	may	may	MD
cord-330553-sukrjl22	98	32	be	be	VB
cord-330553-sukrjl22	98	33	required	require	VBN
cord-330553-sukrjl22	98	34	for	for	IN
cord-330553-sukrjl22	98	35	the	the	DT
cord-330553-sukrjl22	98	36	generation	generation	NN
cord-330553-sukrjl22	98	37	of	of	IN
cord-330553-sukrjl22	98	38	an	an	DT
cord-330553-sukrjl22	98	39	efficient	efficient	JJ
cord-330553-sukrjl22	98	40	T	t	NN
cord-330553-sukrjl22	98	41	cell	cell	NN
cord-330553-sukrjl22	98	42	response	response	NN
cord-330553-sukrjl22	98	43	[	[	-LRB-
cord-330553-sukrjl22	98	44	49	49	CD
cord-330553-sukrjl22	98	45	]	]	-RRB-
cord-330553-sukrjl22	98	46	.	.	.
cord-330553-sukrjl22	99	1	This	this	DT
cord-330553-sukrjl22	99	2	study	study	NN
cord-330553-sukrjl22	99	3	also	also	RB
cord-330553-sukrjl22	99	4	showed	show	VBD
cord-330553-sukrjl22	99	5	that	that	IN
cord-330553-sukrjl22	99	6	microglial	microglial	JJ
cord-330553-sukrjl22	99	7	protection	protection	NN
cord-330553-sukrjl22	99	8	was	be	VBD
cord-330553-sukrjl22	99	9	time	time	NN
cord-330553-sukrjl22	99	10	dependent	dependent	JJ
cord-330553-sukrjl22	99	11	[	[	-LRB-
cord-330553-sukrjl22	99	12	49	49	CD
cord-330553-sukrjl22	99	13	]	]	-RRB-
cord-330553-sukrjl22	99	14	.	.	.
cord-330553-sukrjl22	100	1	Elimination	elimination	NN
cord-330553-sukrjl22	100	2	of	of	IN
cord-330553-sukrjl22	100	3	microglia	microglia	NNS
cord-330553-sukrjl22	100	4	using	use	VBG
cord-330553-sukrjl22	100	5	PLX5622	PLX5622	NNP
cord-330553-sukrjl22	100	6	between	between	IN
cord-330553-sukrjl22	100	7	days	day	NNS
cord-330553-sukrjl22	100	8	0	0	CD
cord-330553-sukrjl22	100	9	and	and	CC
cord-330553-sukrjl22	100	10	6	6	CD
cord-330553-sukrjl22	100	11	post	post	NN
cord-330553-sukrjl22	100	12	-	-	NN
cord-330553-sukrjl22	100	13	infection	infection	NN
cord-330553-sukrjl22	100	14	resulted	result	VBD
cord-330553-sukrjl22	100	15	in	in	IN
cord-330553-sukrjl22	100	16	increased	increase	VBN
cord-330553-sukrjl22	100	17	mortality	mortality	NN
cord-330553-sukrjl22	100	18	in	in	IN
cord-330553-sukrjl22	100	19	infected	infected	JJ
cord-330553-sukrjl22	100	20	mice	mouse	NNS
cord-330553-sukrjl22	101	1	;	;	:
cord-330553-sukrjl22	101	2	however	however	RB
cord-330553-sukrjl22	101	3	,	,	,
cord-330553-sukrjl22	101	4	microglial	microglial	JJ
cord-330553-sukrjl22	101	5	depletion	depletion	NN
cord-330553-sukrjl22	101	6	after	after	IN
cord-330553-sukrjl22	101	7	the	the	DT
cord-330553-sukrjl22	101	8	first	first	JJ
cord-330553-sukrjl22	101	9	6	6	CD
cord-330553-sukrjl22	101	10	days	day	NNS
cord-330553-sukrjl22	101	11	showed	show	VBD
cord-330553-sukrjl22	101	12	no	no	DT
cord-330553-sukrjl22	101	13	effect	effect	NN
cord-330553-sukrjl22	101	14	on	on	IN
cord-330553-sukrjl22	101	15	mortality	mortality	NN
cord-330553-sukrjl22	101	16	[	[	-LRB-
cord-330553-sukrjl22	101	17	49	49	CD
cord-330553-sukrjl22	101	18	]	]	-RRB-
cord-330553-sukrjl22	101	19	.	.	.
cord-330553-sukrjl22	102	1	This	this	DT
cord-330553-sukrjl22	102	2	data	data	NN
cord-330553-sukrjl22	102	3	indicates	indicate	VBZ
cord-330553-sukrjl22	102	4	that	that	IN
cord-330553-sukrjl22	102	5	microglia	microglia	NNS
cord-330553-sukrjl22	102	6	are	be	VBP
cord-330553-sukrjl22	102	7	essential	essential	JJ
cord-330553-sukrjl22	102	8	for	for	IN
cord-330553-sukrjl22	102	9	limiting	limit	VBG
cord-330553-sukrjl22	102	10	viral	viral	JJ
cord-330553-sukrjl22	102	11	growth	growth	NN
cord-330553-sukrjl22	102	12	and	and	CC
cord-330553-sukrjl22	102	13	neuronal	neuronal	JJ
cord-330553-sukrjl22	102	14	cell	cell	NN
cord-330553-sukrjl22	102	15	death	death	NN
cord-330553-sukrjl22	102	16	during	during	IN
cord-330553-sukrjl22	102	17	the	the	DT
cord-330553-sukrjl22	102	18	initial	initial	JJ
cord-330553-sukrjl22	102	19	phase	phase	NN
cord-330553-sukrjl22	102	20	of	of	IN
cord-330553-sukrjl22	102	21	a	a	DT
cord-330553-sukrjl22	102	22	neuroinvasive	neuroinvasive	JJ
cord-330553-sukrjl22	102	23	viral	viral	JJ
cord-330553-sukrjl22	102	24	infection	infection	NN
cord-330553-sukrjl22	102	25	but	but	CC
cord-330553-sukrjl22	102	26	become	become	VBP
cord-330553-sukrjl22	102	27	less	less	RBR
cord-330553-sukrjl22	102	28	important	important	JJ
cord-330553-sukrjl22	102	29	during	during	IN
cord-330553-sukrjl22	102	30	later	later	JJ
cord-330553-sukrjl22	102	31	infection	infection	NN
cord-330553-sukrjl22	102	32	,	,	,
cord-330553-sukrjl22	102	33	when	when	WRB
cord-330553-sukrjl22	102	34	adaptive	adaptive	JJ
cord-330553-sukrjl22	102	35	immune	immune	JJ
cord-330553-sukrjl22	102	36	responses	response	NNS
cord-330553-sukrjl22	102	37	have	have	VBP
cord-330553-sukrjl22	102	38	developed	develop	VBN
cord-330553-sukrjl22	102	39	.	.	.
cord-330553-sukrjl22	103	1	Determination	determination	NN
cord-330553-sukrjl22	103	2	of	of	IN
cord-330553-sukrjl22	103	3	whether	whether	IN
cord-330553-sukrjl22	103	4	microglia	microglia	NNS
cord-330553-sukrjl22	103	5	follow	follow	VBP
cord-330553-sukrjl22	103	6	a	a	DT
cord-330553-sukrjl22	103	7	similar	similar	JJ
cord-330553-sukrjl22	103	8	time	time	NN
cord-330553-sukrjl22	103	9	-	-	HYPH
cord-330553-sukrjl22	103	10	dependent	dependent	JJ
cord-330553-sukrjl22	103	11	role	role	NN
cord-330553-sukrjl22	103	12	following	follow	VBG
cord-330553-sukrjl22	103	13	WNV	WNV	NNP
cord-330553-sukrjl22	103	14	infection	infection	NN
cord-330553-sukrjl22	103	15	in	in	IN
cord-330553-sukrjl22	103	16	the	the	DT
cord-330553-sukrjl22	103	17	CNS	CNS	NNP
cord-330553-sukrjl22	103	18	and	and	CC
cord-330553-sukrjl22	103	19	whether	whether	IN
cord-330553-sukrjl22	103	20	this	this	DT
cord-330553-sukrjl22	103	21	is	be	VBZ
cord-330553-sukrjl22	103	22	associated	associate	VBN
cord-330553-sukrjl22	103	23	with	with	IN
cord-330553-sukrjl22	103	24	changes	change	NNS
cord-330553-sukrjl22	103	25	in	in	IN
cord-330553-sukrjl22	103	26	the	the	DT
cord-330553-sukrjl22	103	27	T	T	NNP
cord-330553-sukrjl22	103	28	cell	cell	NN
cord-330553-sukrjl22	103	29	response	response	NN
cord-330553-sukrjl22	103	30	remains	remain	VBZ
cord-330553-sukrjl22	103	31	to	to	TO
cord-330553-sukrjl22	103	32	be	be	VB
cord-330553-sukrjl22	103	33	determined	determine	VBN
cord-330553-sukrjl22	103	34	.	.	.
cord-330553-sukrjl22	104	1	Collectively	collectively	RB
cord-330553-sukrjl22	104	2	,	,	,
cord-330553-sukrjl22	104	3	the	the	DT
cord-330553-sukrjl22	104	4	studies	study	NNS
cord-330553-sukrjl22	104	5	discussed	discuss	VBN
cord-330553-sukrjl22	104	6	above	above	IN
cord-330553-sukrjl22	104	7	reveal	reveal	VB
cord-330553-sukrjl22	104	8	the	the	DT
cord-330553-sukrjl22	104	9	critical	critical	JJ
cord-330553-sukrjl22	104	10	role	role	NN
cord-330553-sukrjl22	104	11	microglia	microglia	NN
cord-330553-sukrjl22	104	12	play	play	VBP
cord-330553-sukrjl22	104	13	in	in	IN
cord-330553-sukrjl22	104	14	protecting	protect	VBG
cord-330553-sukrjl22	104	15	the	the	DT
cord-330553-sukrjl22	104	16	host	host	NN
cord-330553-sukrjl22	104	17	from	from	IN
cord-330553-sukrjl22	104	18	WNV	WNV	NNP
cord-330553-sukrjl22	104	19	-	-	HYPH
cord-330553-sukrjl22	104	20	induced	induce	VBN
cord-330553-sukrjl22	104	21	CNS	CNS	NNP
cord-330553-sukrjl22	104	22	disease	disease	NN
cord-330553-sukrjl22	104	23	.	.	.
cord-330553-sukrjl22	105	1	Elimination	elimination	NN
cord-330553-sukrjl22	105	2	of	of	IN
cord-330553-sukrjl22	105	3	microglia	microglia	NN
cord-330553-sukrjl22	105	4	during	during	IN
cord-330553-sukrjl22	105	5	WNV	WNV	NNP
cord-330553-sukrjl22	105	6	encephalitis	encephalitis	RB
cord-330553-sukrjl22	105	7	led	lead	VBD
cord-330553-sukrjl22	105	8	to	to	IN
cord-330553-sukrjl22	105	9	increased	increase	VBN
cord-330553-sukrjl22	105	10	viral	viral	JJ
cord-330553-sukrjl22	105	11	titers	titer	NNS
cord-330553-sukrjl22	105	12	within	within	IN
cord-330553-sukrjl22	105	13	the	the	DT
cord-330553-sukrjl22	105	14	brain	brain	NN
cord-330553-sukrjl22	105	15	and	and	CC
cord-330553-sukrjl22	105	16	increased	increase	VBN
cord-330553-sukrjl22	105	17	mortality	mortality	NN
cord-330553-sukrjl22	105	18	in	in	IN
cord-330553-sukrjl22	105	19	mice	mouse	NNS
cord-330553-sukrjl22	105	20	.	.	.
cord-330553-sukrjl22	106	1	Further	further	JJ
cord-330553-sukrjl22	106	2	studies	study	NNS
cord-330553-sukrjl22	106	3	are	be	VBP
cord-330553-sukrjl22	106	4	needed	need	VBN
cord-330553-sukrjl22	106	5	to	to	TO
cord-330553-sukrjl22	106	6	determine	determine	VB
cord-330553-sukrjl22	106	7	the	the	DT
cord-330553-sukrjl22	106	8	mechanism	mechanism	NN
cord-330553-sukrjl22	106	9	by	by	IN
cord-330553-sukrjl22	106	10	which	which	WDT
cord-330553-sukrjl22	106	11	microglia	microglia	NNS
cord-330553-sukrjl22	106	12	protect	protect	VBP
cord-330553-sukrjl22	106	13	the	the	DT
cord-330553-sukrjl22	106	14	CNS	CNS	NNP
cord-330553-sukrjl22	106	15	from	from	IN
cord-330553-sukrjl22	106	16	WNV	WNV	NNP
cord-330553-sukrjl22	106	17	infection	infection	NN
cord-330553-sukrjl22	106	18	.	.	.
cord-330553-sukrjl22	107	1	Potential	potential	JJ
cord-330553-sukrjl22	107	2	mechanisms	mechanism	NNS
cord-330553-sukrjl22	107	3	include	include	VBP
cord-330553-sukrjl22	107	4	phagocytosis	phagocytosis	NN
cord-330553-sukrjl22	107	5	of	of	IN
cord-330553-sukrjl22	107	6	WNV	WNV	NNP
cord-330553-sukrjl22	107	7	-	-	HYPH
cord-330553-sukrjl22	107	8	infected	infect	VBN
cord-330553-sukrjl22	107	9	neurons	neuron	NNS
cord-330553-sukrjl22	107	10	,	,	,
cord-330553-sukrjl22	107	11	production	production	NN
cord-330553-sukrjl22	107	12	of	of	IN
cord-330553-sukrjl22	107	13	inflammatory	inflammatory	JJ
cord-330553-sukrjl22	107	14	cytokines	cytokine	NNS
cord-330553-sukrjl22	107	15	/	/	SYM
cord-330553-sukrjl22	107	16	chemokines	chemokine	NNS
cord-330553-sukrjl22	107	17	,	,	,
cord-330553-sukrjl22	107	18	and	and	CC
cord-330553-sukrjl22	107	19	signaling	signal	VBG
cord-330553-sukrjl22	107	20	to	to	IN
cord-330553-sukrjl22	107	21	the	the	DT
cord-330553-sukrjl22	107	22	adaptive	adaptive	JJ
cord-330553-sukrjl22	107	23	immune	immune	JJ
cord-330553-sukrjl22	107	24	system	system	NN
cord-330553-sukrjl22	107	25	.	.	.
cord-330553-sukrjl22	108	1	Matrix	matrix	NN
cord-330553-sukrjl22	108	2	metalloproteinases	metalloproteinase	NNS
cord-330553-sukrjl22	108	3	(	(	-LRB-
cord-330553-sukrjl22	108	4	MMPs	MMPs	NNP
cord-330553-sukrjl22	108	5	)	)	-RRB-
cord-330553-sukrjl22	108	6	are	be	VBP
cord-330553-sukrjl22	108	7	a	a	DT
cord-330553-sukrjl22	108	8	family	family	NN
cord-330553-sukrjl22	108	9	of	of	IN
cord-330553-sukrjl22	108	10	proteins	protein	NNS
cord-330553-sukrjl22	108	11	whose	whose	WP$
cord-330553-sukrjl22	108	12	major	major	JJ
cord-330553-sukrjl22	108	13	function	function	NN
cord-330553-sukrjl22	108	14	is	be	VBZ
cord-330553-sukrjl22	108	15	remodeling	remodel	VBG
cord-330553-sukrjl22	108	16	the	the	DT
cord-330553-sukrjl22	108	17	extracellular	extracellular	JJ
cord-330553-sukrjl22	108	18	complex	complex	NN
cord-330553-sukrjl22	108	19	(	(	-LRB-
cord-330553-sukrjl22	108	20	EC	EC	NNP
cord-330553-sukrjl22	108	21	)	)	-RRB-
cord-330553-sukrjl22	108	22	of	of	IN
cord-330553-sukrjl22	108	23	the	the	DT
cord-330553-sukrjl22	108	24	BBB	BBB	NNP
cord-330553-sukrjl22	108	25	[	[	-LRB-
cord-330553-sukrjl22	108	26	77	77	CD
cord-330553-sukrjl22	108	27	,	,	,
cord-330553-sukrjl22	108	28	78	78	CD
cord-330553-sukrjl22	108	29	]	]	-RRB-
cord-330553-sukrjl22	108	30	.	.	.
cord-330553-sukrjl22	109	1	They	-PRON-	PRP
cord-330553-sukrjl22	109	2	have	have	VBP
cord-330553-sukrjl22	109	3	also	also	RB
cord-330553-sukrjl22	109	4	been	be	VBN
cord-330553-sukrjl22	109	5	shown	show	VBN
cord-330553-sukrjl22	109	6	to	to	TO
cord-330553-sukrjl22	109	7	play	play	VB
cord-330553-sukrjl22	109	8	a	a	DT
cord-330553-sukrjl22	109	9	role	role	NN
cord-330553-sukrjl22	109	10	in	in	IN
cord-330553-sukrjl22	109	11	immunity	immunity	NN
cord-330553-sukrjl22	109	12	by	by	IN
cord-330553-sukrjl22	109	13	modulating	modulate	VBG
cord-330553-sukrjl22	109	14	the	the	DT
cord-330553-sukrjl22	109	15	trafficking	trafficking	NN
cord-330553-sukrjl22	109	16	of	of	IN
cord-330553-sukrjl22	109	17	immune	immune	JJ
cord-330553-sukrjl22	109	18	cells	cell	NNS
cord-330553-sukrjl22	109	19	into	into	IN
cord-330553-sukrjl22	109	20	the	the	DT
cord-330553-sukrjl22	109	21	CNS	CNS	NNP
cord-330553-sukrjl22	109	22	[	[	-LRB-
cord-330553-sukrjl22	109	23	79	79	CD
cord-330553-sukrjl22	109	24	]	]	-RRB-
cord-330553-sukrjl22	109	25	.	.	.
cord-330553-sukrjl22	110	1	MMP9	MMP9	NNP
cord-330553-sukrjl22	110	2	,	,	,
cord-330553-sukrjl22	110	3	is	be	VBZ
cord-330553-sukrjl22	110	4	expressed	express	VBN
cord-330553-sukrjl22	110	5	by	by	IN
cord-330553-sukrjl22	110	6	microglia	microglia	NNS
cord-330553-sukrjl22	110	7	[	[	-LRB-
cord-330553-sukrjl22	110	8	78	78	CD
cord-330553-sukrjl22	110	9	]	]	-RRB-
cord-330553-sukrjl22	110	10	,	,	,
cord-330553-sukrjl22	110	11	and	and	CC
cord-330553-sukrjl22	110	12	has	have	VBZ
cord-330553-sukrjl22	110	13	been	be	VBN
cord-330553-sukrjl22	110	14	shown	show	VBN
cord-330553-sukrjl22	110	15	to	to	TO
cord-330553-sukrjl22	110	16	be	be	VB
cord-330553-sukrjl22	110	17	important	important	JJ
cord-330553-sukrjl22	110	18	for	for	IN
cord-330553-sukrjl22	110	19	WNV	WNV	NNP
cord-330553-sukrjl22	110	20	entry	entry	NN
cord-330553-sukrjl22	110	21	into	into	IN
cord-330553-sukrjl22	110	22	the	the	DT
cord-330553-sukrjl22	110	23	brain	brain	NN
cord-330553-sukrjl22	110	24	[	[	-LRB-
cord-330553-sukrjl22	110	25	77	77	CD
cord-330553-sukrjl22	110	26	]	]	-RRB-
cord-330553-sukrjl22	110	27	.	.	.
cord-330553-sukrjl22	111	1	MMP9	mmp9	CD
cord-330553-sukrjl22	111	2	knockout	knockout	NN
cord-330553-sukrjl22	111	3	mice	mouse	NNS
cord-330553-sukrjl22	111	4	infected	infect	VBN
cord-330553-sukrjl22	111	5	with	with	IN
cord-330553-sukrjl22	111	6	WNV	WNV	NNP
cord-330553-sukrjl22	111	7	show	show	NN
cord-330553-sukrjl22	111	8	decreased	decrease	VBD
cord-330553-sukrjl22	111	9	viral	viral	JJ
cord-330553-sukrjl22	111	10	loads	load	NNS
cord-330553-sukrjl22	111	11	in	in	IN
cord-330553-sukrjl22	111	12	the	the	DT
cord-330553-sukrjl22	111	13	brain	brain	NN
cord-330553-sukrjl22	111	14	,	,	,
cord-330553-sukrjl22	111	15	but	but	CC
cord-330553-sukrjl22	111	16	not	not	RB
cord-330553-sukrjl22	111	17	the	the	DT
cord-330553-sukrjl22	111	18	periphery	periphery	NN
cord-330553-sukrjl22	111	19	,	,	,
cord-330553-sukrjl22	111	20	and	and	CC
cord-330553-sukrjl22	111	21	increased	increase	VBN
cord-330553-sukrjl22	111	22	survival	survival	NN
cord-330553-sukrjl22	111	23	when	when	WRB
cord-330553-sukrjl22	111	24	compared	compare	VBN
cord-330553-sukrjl22	111	25	to	to	IN
cord-330553-sukrjl22	111	26	wild	wild	JJ
cord-330553-sukrjl22	111	27	-	-	HYPH
cord-330553-sukrjl22	111	28	type	type	NN
cord-330553-sukrjl22	111	29	(	(	-LRB-
cord-330553-sukrjl22	111	30	WT	WT	NNP
cord-330553-sukrjl22	111	31	)	)	-RRB-
cord-330553-sukrjl22	111	32	mice	mouse	NNS
cord-330553-sukrjl22	111	33	[	[	-LRB-
cord-330553-sukrjl22	111	34	77	77	CD
cord-330553-sukrjl22	111	35	]	]	-RRB-
cord-330553-sukrjl22	111	36	.	.	.
cord-330553-sukrjl22	112	1	Resistance	resistance	NN
cord-330553-sukrjl22	112	2	to	to	IN
cord-330553-sukrjl22	112	3	lethal	lethal	JJ
cord-330553-sukrjl22	112	4	WNV	WNV	NNP
cord-330553-sukrjl22	112	5	infection	infection	NN
cord-330553-sukrjl22	112	6	coincided	coincide	VBD
cord-330553-sukrjl22	112	7	with	with	IN
cord-330553-sukrjl22	112	8	an	an	DT
cord-330553-sukrjl22	112	9	intact	intact	JJ
cord-330553-sukrjl22	112	10	BBB	bbb	NN
cord-330553-sukrjl22	112	11	as	as	IN
cord-330553-sukrjl22	112	12	shown	show	VBN
cord-330553-sukrjl22	112	13	by	by	IN
cord-330553-sukrjl22	112	14	reduced	reduce	VBN
cord-330553-sukrjl22	112	15	Evan	Evan	NNP
cord-330553-sukrjl22	112	16	's	's	POS
cord-330553-sukrjl22	112	17	Blue	Blue	NNP
cord-330553-sukrjl22	112	18	Dye	Dye	NNP
cord-330553-sukrjl22	112	19	leakage	leakage	NN
cord-330553-sukrjl22	112	20	into	into	IN
cord-330553-sukrjl22	112	21	the	the	DT
cord-330553-sukrjl22	112	22	brain	brain	NN
cord-330553-sukrjl22	112	23	,	,	,
cord-330553-sukrjl22	112	24	indicating	indicate	VBG
cord-330553-sukrjl22	112	25	a	a	DT
cord-330553-sukrjl22	112	26	role	role	NN
cord-330553-sukrjl22	112	27	for	for	IN
cord-330553-sukrjl22	112	28	MM9P	MM9P	NNS
cord-330553-sukrjl22	112	29	in	in	IN
cord-330553-sukrjl22	112	30	altering	alter	VBG
cord-330553-sukrjl22	112	31	permeability	permeability	NN
cord-330553-sukrjl22	112	32	of	of	IN
cord-330553-sukrjl22	112	33	the	the	DT
cord-330553-sukrjl22	112	34	BBB	BBB	NNP
cord-330553-sukrjl22	112	35	during	during	IN
cord-330553-sukrjl22	112	36	a	a	DT
cord-330553-sukrjl22	112	37	WNV	WNV	NNP
cord-330553-sukrjl22	112	38	infection	infection	NN
cord-330553-sukrjl22	112	39	[	[	-LRB-
cord-330553-sukrjl22	112	40	77	77	CD
cord-330553-sukrjl22	112	41	]	]	-RRB-
cord-330553-sukrjl22	112	42	.	.	.
cord-330553-sukrjl22	113	1	An	an	DT
cord-330553-sukrjl22	113	2	additional	additional	JJ
cord-330553-sukrjl22	113	3	mechanism	mechanism	NN
cord-330553-sukrjl22	113	4	by	by	IN
cord-330553-sukrjl22	113	5	which	which	WDT
cord-330553-sukrjl22	113	6	microglia	microglia	NNS
cord-330553-sukrjl22	113	7	may	may	MD
cord-330553-sukrjl22	113	8	contribute	contribute	VB
cord-330553-sukrjl22	113	9	to	to	IN
cord-330553-sukrjl22	113	10	WNV	WNV	NNP
cord-330553-sukrjl22	113	11	entry	entry	NN
cord-330553-sukrjl22	113	12	into	into	IN
cord-330553-sukrjl22	113	13	the	the	DT
cord-330553-sukrjl22	113	14	brain	brain	NN
cord-330553-sukrjl22	113	15	involves	involve	VBZ
cord-330553-sukrjl22	113	16	intercellular	intercellular	JJ
cord-330553-sukrjl22	113	17	adhesion	adhesion	NN
cord-330553-sukrjl22	113	18	molecule	molecule	NN
cord-330553-sukrjl22	113	19	(	(	-LRB-
cord-330553-sukrjl22	113	20	ICAM-1	ICAM-1	NNP
cord-330553-sukrjl22	113	21	)	)	-RRB-
cord-330553-sukrjl22	113	22	,	,	,
cord-330553-sukrjl22	113	23	a	a	DT
cord-330553-sukrjl22	113	24	surface	surface	NN
cord-330553-sukrjl22	113	25	glycoprotein	glycoprotein	NN
cord-330553-sukrjl22	113	26	involved	involve	VBN
cord-330553-sukrjl22	113	27	in	in	IN
cord-330553-sukrjl22	113	28	cellular	cellular	JJ
cord-330553-sukrjl22	113	29	extravasation	extravasation	NN
cord-330553-sukrjl22	113	30	into	into	IN
cord-330553-sukrjl22	113	31	sites	site	NNS
cord-330553-sukrjl22	113	32	of	of	IN
cord-330553-sukrjl22	113	33	inflammation	inflammation	NN
cord-330553-sukrjl22	113	34	.	.	.
cord-330553-sukrjl22	114	1	ICAM-1	ICAM-1	NNP
cord-330553-sukrjl22	114	2	is	be	VBZ
cord-330553-sukrjl22	114	3	expressed	express	VBN
cord-330553-sukrjl22	114	4	by	by	IN
cord-330553-sukrjl22	114	5	several	several	JJ
cord-330553-sukrjl22	114	6	cell	cell	NN
cord-330553-sukrjl22	114	7	types	type	NNS
cord-330553-sukrjl22	114	8	including	include	VBG
cord-330553-sukrjl22	114	9	microglia	microglia	NNS
cord-330553-sukrjl22	114	10	[	[	-LRB-
cord-330553-sukrjl22	114	11	80	80	CD
cord-330553-sukrjl22	114	12	]	]	-RRB-
cord-330553-sukrjl22	114	13	.	.	.
cord-330553-sukrjl22	115	1	The	the	DT
cord-330553-sukrjl22	115	2	expression	expression	NN
cord-330553-sukrjl22	115	3	of	of	IN
cord-330553-sukrjl22	115	4	ICAM-1	icam-1	NN
cord-330553-sukrjl22	115	5	on	on	IN
cord-330553-sukrjl22	115	6	microglia	microglia	NNS
cord-330553-sukrjl22	115	7	may	may	MD
cord-330553-sukrjl22	115	8	contribute	contribute	VB
cord-330553-sukrjl22	115	9	to	to	IN
cord-330553-sukrjl22	115	10	extravasation	extravasation	NN
cord-330553-sukrjl22	115	11	of	of	IN
cord-330553-sukrjl22	115	12	leukocytes	leukocyte	NNS
cord-330553-sukrjl22	115	13	via	via	IN
cord-330553-sukrjl22	115	14	the	the	DT
cord-330553-sukrjl22	115	15	"	"	``
cord-330553-sukrjl22	115	16	Trojan	Trojan	NNP
cord-330553-sukrjl22	115	17	horse	horse	NN
cord-330553-sukrjl22	115	18	"	"	''
cord-330553-sukrjl22	115	19	method	method	NN
cord-330553-sukrjl22	115	20	,	,	,
cord-330553-sukrjl22	115	21	in	in	IN
cord-330553-sukrjl22	115	22	which	which	WDT
cord-330553-sukrjl22	115	23	the	the	DT
cord-330553-sukrjl22	115	24	virus	virus	NN
cord-330553-sukrjl22	115	25	gains	gain	VBZ
cord-330553-sukrjl22	115	26	access	access	NN
cord-330553-sukrjl22	115	27	to	to	IN
cord-330553-sukrjl22	115	28	the	the	DT
cord-330553-sukrjl22	115	29	CNS	CNS	NNP
cord-330553-sukrjl22	115	30	through	through	IN
cord-330553-sukrjl22	115	31	infected	infected	JJ
cord-330553-sukrjl22	115	32	leukocytes	leukocyte	NNS
cord-330553-sukrjl22	115	33	[	[	-LRB-
cord-330553-sukrjl22	115	34	17	17	CD
cord-330553-sukrjl22	115	35	,	,	,
cord-330553-sukrjl22	115	36	81	81	CD
cord-330553-sukrjl22	115	37	]	]	-RRB-
cord-330553-sukrjl22	115	38	.	.	.
cord-330553-sukrjl22	116	1	Indeed	indeed	RB
cord-330553-sukrjl22	116	2	,	,	,
cord-330553-sukrjl22	116	3	WNV	WNV	NNP
cord-330553-sukrjl22	116	4	infection	infection	NN
cord-330553-sukrjl22	116	5	has	have	VBZ
cord-330553-sukrjl22	116	6	been	be	VBN
cord-330553-sukrjl22	116	7	shown	show	VBN
cord-330553-sukrjl22	116	8	to	to	TO
cord-330553-sukrjl22	116	9	induce	induce	VB
cord-330553-sukrjl22	116	10	ICAM-1	icam-1	JJ
cord-330553-sukrjl22	116	11	expression	expression	NN
cord-330553-sukrjl22	116	12	in	in	IN
cord-330553-sukrjl22	116	13	human	human	JJ
cord-330553-sukrjl22	116	14	endothelial	endothelial	JJ
cord-330553-sukrjl22	116	15	cells	cell	NNS
cord-330553-sukrjl22	116	16	and	and	CC
cord-330553-sukrjl22	116	17	mouse	mouse	NN
cord-330553-sukrjl22	116	18	brains	brain	NNS
cord-330553-sukrjl22	116	19	,	,	,
cord-330553-sukrjl22	116	20	leading	lead	VBG
cord-330553-sukrjl22	116	21	to	to	IN
cord-330553-sukrjl22	116	22	disruption	disruption	NN
cord-330553-sukrjl22	116	23	of	of	IN
cord-330553-sukrjl22	116	24	the	the	DT
cord-330553-sukrjl22	116	25	BBB	BBB	NNP
cord-330553-sukrjl22	116	26	and	and	CC
cord-330553-sukrjl22	116	27	increased	increase	VBN
cord-330553-sukrjl22	116	28	leukocyte	leukocyte	NN
cord-330553-sukrjl22	116	29	infiltration	infiltration	NN
cord-330553-sukrjl22	116	30	[	[	-LRB-
cord-330553-sukrjl22	116	31	82	82	CD
cord-330553-sukrjl22	116	32	]	]	-RRB-
cord-330553-sukrjl22	116	33	.	.	.
cord-330553-sukrjl22	117	1	It	-PRON-	PRP
cord-330553-sukrjl22	117	2	was	be	VBD
cord-330553-sukrjl22	117	3	also	also	RB
cord-330553-sukrjl22	117	4	found	find	VBN
cord-330553-sukrjl22	117	5	that	that	IN
cord-330553-sukrjl22	117	6	this	this	DT
cord-330553-sukrjl22	117	7	process	process	NN
cord-330553-sukrjl22	117	8	can	can	MD
cord-330553-sukrjl22	117	9	be	be	VB
cord-330553-sukrjl22	117	10	reversed	reverse	VBN
cord-330553-sukrjl22	117	11	through	through	IN
cord-330553-sukrjl22	117	12	the	the	DT
cord-330553-sukrjl22	117	13	use	use	NN
cord-330553-sukrjl22	117	14	of	of	IN
cord-330553-sukrjl22	117	15	blocking	block	VBG
cord-330553-sukrjl22	117	16	antibodies	antibody	NNS
cord-330553-sukrjl22	117	17	against	against	IN
cord-330553-sukrjl22	117	18	ICAM-1	ICAM-1	NNP
cord-330553-sukrjl22	117	19	[	[	-LRB-
cord-330553-sukrjl22	117	20	82	82	CD
cord-330553-sukrjl22	117	21	]	]	-RRB-
cord-330553-sukrjl22	117	22	.	.	.
cord-330553-sukrjl22	118	1	Individuals	individual	NNS
cord-330553-sukrjl22	118	2	recovering	recover	VBG
cord-330553-sukrjl22	118	3	from	from	IN
cord-330553-sukrjl22	118	4	WNV	WNV	NNP
cord-330553-sukrjl22	118	5	encephalitis	encephalitis	NN
cord-330553-sukrjl22	118	6	may	may	MD
cord-330553-sukrjl22	118	7	experience	experience	VB
cord-330553-sukrjl22	118	8	long	long	JJ
cord-330553-sukrjl22	118	9	-	-	HYPH
cord-330553-sukrjl22	118	10	term	term	NN
cord-330553-sukrjl22	118	11	neurological	neurological	JJ
cord-330553-sukrjl22	118	12	deficits	deficit	NNS
cord-330553-sukrjl22	118	13	resulting	result	VBG
cord-330553-sukrjl22	118	14	from	from	IN
cord-330553-sukrjl22	118	15	the	the	DT
cord-330553-sukrjl22	118	16	infection	infection	NN
cord-330553-sukrjl22	118	17	[	[	-LRB-
cord-330553-sukrjl22	118	18	3	3	CD
cord-330553-sukrjl22	118	19	]	]	-RRB-
cord-330553-sukrjl22	118	20	.	.	.
cord-330553-sukrjl22	119	1	This	this	DT
cord-330553-sukrjl22	119	2	effect	effect	NN
cord-330553-sukrjl22	119	3	of	of	IN
cord-330553-sukrjl22	119	4	WNV	WNV	NNP
cord-330553-sukrjl22	119	5	infection	infection	NN
cord-330553-sukrjl22	119	6	of	of	IN
cord-330553-sukrjl22	119	7	the	the	DT
cord-330553-sukrjl22	119	8	CNS	CNS	NNP
cord-330553-sukrjl22	119	9	is	be	VBZ
cord-330553-sukrjl22	119	10	being	be	VBG
cord-330553-sukrjl22	119	11	extensively	extensively	RB
cord-330553-sukrjl22	119	12	studied	study	VBN
cord-330553-sukrjl22	119	13	as	as	IN
cord-330553-sukrjl22	119	14	an	an	DT
cord-330553-sukrjl22	119	15	increased	increase	VBN
cord-330553-sukrjl22	119	16	understanding	understanding	NN
cord-330553-sukrjl22	119	17	of	of	IN
cord-330553-sukrjl22	119	18	why	why	WRB
cord-330553-sukrjl22	119	19	these	these	DT
cord-330553-sukrjl22	119	20	impairments	impairment	NNS
cord-330553-sukrjl22	119	21	occur	occur	VBP
cord-330553-sukrjl22	119	22	will	will	MD
cord-330553-sukrjl22	119	23	likely	likely	RB
cord-330553-sukrjl22	119	24	lead	lead	VB
cord-330553-sukrjl22	119	25	to	to	IN
cord-330553-sukrjl22	119	26	an	an	DT
cord-330553-sukrjl22	119	27	improvement	improvement	NN
cord-330553-sukrjl22	119	28	in	in	IN
cord-330553-sukrjl22	119	29	the	the	DT
cord-330553-sukrjl22	119	30	long	long	JJ
cord-330553-sukrjl22	119	31	-	-	HYPH
cord-330553-sukrjl22	119	32	term	term	NN
cord-330553-sukrjl22	119	33	outcomes	outcome	NNS
cord-330553-sukrjl22	119	34	of	of	IN
cord-330553-sukrjl22	119	35	recovering	recover	VBG
cord-330553-sukrjl22	119	36	patients	patient	NNS
cord-330553-sukrjl22	119	37	.	.	.
cord-330553-sukrjl22	120	1	A	a	DT
cord-330553-sukrjl22	120	2	predominant	predominant	JJ
cord-330553-sukrjl22	120	3	theory	theory	NN
cord-330553-sukrjl22	120	4	is	be	VBZ
cord-330553-sukrjl22	120	5	that	that	IN
cord-330553-sukrjl22	120	6	microglia	microglia	NN
cord-330553-sukrjl22	120	7	activated	activate	VBN
cord-330553-sukrjl22	120	8	by	by	IN
cord-330553-sukrjl22	120	9	memory	memory	NN
cord-330553-sukrjl22	120	10	T	T	NNP
cord-330553-sukrjl22	120	11	cells	cell	NNS
cord-330553-sukrjl22	120	12	may	may	MD
cord-330553-sukrjl22	120	13	contribute	contribute	VB
cord-330553-sukrjl22	120	14	to	to	IN
cord-330553-sukrjl22	120	15	neuronal	neuronal	JJ
cord-330553-sukrjl22	120	16	damage	damage	NN
cord-330553-sukrjl22	120	17	following	follow	VBG
cord-330553-sukrjl22	120	18	infection	infection	NN
cord-330553-sukrjl22	120	19	with	with	IN
cord-330553-sukrjl22	120	20	WNV	WNV	NNP
cord-330553-sukrjl22	120	21	[	[	-LRB-
cord-330553-sukrjl22	120	22	83	83	CD
cord-330553-sukrjl22	120	23	,	,	,
cord-330553-sukrjl22	120	24	84	84	CD
cord-330553-sukrjl22	120	25	]	]	-RRB-
cord-330553-sukrjl22	120	26	.	.	.
cord-330553-sukrjl22	121	1	Following	follow	VBG
cord-330553-sukrjl22	121	2	initiation	initiation	NN
cord-330553-sukrjl22	121	3	of	of	IN
cord-330553-sukrjl22	121	4	innate	innate	JJ
cord-330553-sukrjl22	121	5	immune	immune	JJ
cord-330553-sukrjl22	121	6	responses	response	NNS
cord-330553-sukrjl22	121	7	,	,	,
cord-330553-sukrjl22	121	8	activated	activate	VBN
cord-330553-sukrjl22	121	9	microglia	microglia	NN
cord-330553-sukrjl22	121	10	release	release	NN
cord-330553-sukrjl22	121	11	cytokines	cytokine	NNS
cord-330553-sukrjl22	121	12	that	that	WDT
cord-330553-sukrjl22	121	13	signal	signal	VBP
cord-330553-sukrjl22	121	14	the	the	DT
cord-330553-sukrjl22	121	15	peripheral	peripheral	JJ
cord-330553-sukrjl22	121	16	immune	immune	JJ
cord-330553-sukrjl22	121	17	cells	cell	NNS
cord-330553-sukrjl22	121	18	to	to	TO
cord-330553-sukrjl22	121	19	infiltrate	infiltrate	VB
cord-330553-sukrjl22	121	20	the	the	DT
cord-330553-sukrjl22	121	21	CNS	CNS	NNP
cord-330553-sukrjl22	121	22	to	to	TO
cord-330553-sukrjl22	121	23	clear	clear	VB
cord-330553-sukrjl22	121	24	the	the	DT
cord-330553-sukrjl22	121	25	viral	viral	JJ
cord-330553-sukrjl22	121	26	infection	infection	NN
cord-330553-sukrjl22	121	27	[	[	-LRB-
cord-330553-sukrjl22	121	28	24	24	CD
cord-330553-sukrjl22	121	29	,	,	,
cord-330553-sukrjl22	121	30	28	28	CD
cord-330553-sukrjl22	121	31	]	]	-RRB-
cord-330553-sukrjl22	121	32	.	.	.
cord-330553-sukrjl22	122	1	CD8	CD8	NNP
cord-330553-sukrjl22	122	2	+	+	CC
cord-330553-sukrjl22	122	3	T	T	NNP
cord-330553-sukrjl22	122	4	cells	cell	NNS
cord-330553-sukrjl22	122	5	mediate	mediate	VBP
cord-330553-sukrjl22	122	6	viral	viral	JJ
cord-330553-sukrjl22	122	7	control	control	NN
cord-330553-sukrjl22	122	8	through	through	IN
cord-330553-sukrjl22	122	9	the	the	DT
cord-330553-sukrjl22	122	10	secretion	secretion	NN
cord-330553-sukrjl22	122	11	of	of	IN
cord-330553-sukrjl22	122	12	effector	effector	NN
cord-330553-sukrjl22	122	13	molecules	molecule	NNS
cord-330553-sukrjl22	122	14	such	such	JJ
cord-330553-sukrjl22	122	15	as	as	IN
cord-330553-sukrjl22	122	16	granzymes	granzymes	NNP
cord-330553-sukrjl22	122	17	,	,	,
cord-330553-sukrjl22	122	18	perforin	perforin	NNP
cord-330553-sukrjl22	122	19	,	,	,
cord-330553-sukrjl22	122	20	and	and	CC
cord-330553-sukrjl22	122	21	interferon	interferon	NN
cord-330553-sukrjl22	122	22	-	-	HYPH
cord-330553-sukrjl22	122	23	γ	γ	NN
cord-330553-sukrjl22	122	24	(	(	-LRB-
cord-330553-sukrjl22	122	25	IFNγ	IFNγ	NNS
cord-330553-sukrjl22	122	26	)	)	-RRB-
cord-330553-sukrjl22	122	27	[	[	-LRB-
cord-330553-sukrjl22	122	28	85	85	CD
cord-330553-sukrjl22	122	29	]	]	-RRB-
cord-330553-sukrjl22	122	30	.	.	.
cord-330553-sukrjl22	123	1	While	while	IN
cord-330553-sukrjl22	123	2	CD8	CD8	NNP
cord-330553-sukrjl22	123	3	+	+	CC
cord-330553-sukrjl22	123	4	T	T	NNP
cord-330553-sukrjl22	123	5	cells	cell	NNS
cord-330553-sukrjl22	123	6	are	be	VBP
cord-330553-sukrjl22	123	7	necessary	necessary	JJ
cord-330553-sukrjl22	123	8	for	for	IN
cord-330553-sukrjl22	123	9	proper	proper	JJ
cord-330553-sukrjl22	123	10	clearance	clearance	NN
cord-330553-sukrjl22	123	11	of	of	IN
cord-330553-sukrjl22	123	12	virus	virus	NN
cord-330553-sukrjl22	123	13	from	from	IN
cord-330553-sukrjl22	123	14	the	the	DT
cord-330553-sukrjl22	123	15	CNS	CNS	NNP
cord-330553-sukrjl22	123	16	[	[	-LRB-
cord-330553-sukrjl22	123	17	86	86	CD
cord-330553-sukrjl22	123	18	,	,	,
cord-330553-sukrjl22	123	19	87	87	CD
cord-330553-sukrjl22	123	20	]	]	-RRB-
cord-330553-sukrjl22	123	21	,	,	,
cord-330553-sukrjl22	123	22	they	-PRON-	PRP
cord-330553-sukrjl22	123	23	also	also	RB
cord-330553-sukrjl22	123	24	seem	seem	VBP
cord-330553-sukrjl22	123	25	to	to	TO
cord-330553-sukrjl22	123	26	contribute	contribute	VB
cord-330553-sukrjl22	123	27	to	to	IN
cord-330553-sukrjl22	123	28	neurological	neurological	JJ
cord-330553-sukrjl22	123	29	deficits	deficit	NNS
cord-330553-sukrjl22	123	30	following	follow	VBG
cord-330553-sukrjl22	123	31	WNV	WNV	NNP
cord-330553-sukrjl22	123	32	infection	infection	NN
cord-330553-sukrjl22	123	33	[	[	-LRB-
cord-330553-sukrjl22	123	34	83	83	CD
cord-330553-sukrjl22	123	35	,	,	,
cord-330553-sukrjl22	123	36	84	84	CD
cord-330553-sukrjl22	123	37	,	,	,
cord-330553-sukrjl22	123	38	88	88	CD
cord-330553-sukrjl22	123	39	]	]	-RRB-
cord-330553-sukrjl22	123	40	.	.	.
cord-330553-sukrjl22	124	1	Once	once	RB
cord-330553-sukrjl22	124	2	in	in	IN
cord-330553-sukrjl22	124	3	the	the	DT
cord-330553-sukrjl22	124	4	CNS	CNS	NNP
cord-330553-sukrjl22	124	5	,	,	,
cord-330553-sukrjl22	124	6	CD8	CD8	NNP
cord-330553-sukrjl22	124	7	+	+	CC
cord-330553-sukrjl22	124	8	T	T	NNP
cord-330553-sukrjl22	124	9	cells	cell	NNS
cord-330553-sukrjl22	124	10	will	will	MD
cord-330553-sukrjl22	124	11	differentiate	differentiate	VB
cord-330553-sukrjl22	124	12	into	into	IN
cord-330553-sukrjl22	124	13	brain	brain	NN
cord-330553-sukrjl22	124	14	resident	resident	NN
cord-330553-sukrjl22	124	15	memory	memory	NN
cord-330553-sukrjl22	124	16	T	T	NNP
cord-330553-sukrjl22	124	17	cells	cell	NNS
cord-330553-sukrjl22	124	18	,	,	,
cord-330553-sukrjl22	124	19	which	which	WDT
cord-330553-sukrjl22	124	20	are	be	VBP
cord-330553-sukrjl22	124	21	important	important	JJ
cord-330553-sukrjl22	124	22	for	for	IN
cord-330553-sukrjl22	124	23	protection	protection	NN
cord-330553-sukrjl22	124	24	from	from	IN
cord-330553-sukrjl22	124	25	reinfection	reinfection	NN
cord-330553-sukrjl22	124	26	[	[	-LRB-
cord-330553-sukrjl22	124	27	85	85	CD
cord-330553-sukrjl22	124	28	]	]	-RRB-
cord-330553-sukrjl22	124	29	.	.	.
cord-330553-sukrjl22	125	1	These	these	DT
cord-330553-sukrjl22	125	2	T	t	NN
cord-330553-sukrjl22	125	3	cells	cell	NNS
cord-330553-sukrjl22	125	4	remain	remain	VBP
cord-330553-sukrjl22	125	5	within	within	IN
cord-330553-sukrjl22	125	6	the	the	DT
cord-330553-sukrjl22	125	7	CNS	CNS	NNP
cord-330553-sukrjl22	125	8	for	for	IN
cord-330553-sukrjl22	125	9	months	month	NNS
cord-330553-sukrjl22	125	10	to	to	IN
cord-330553-sukrjl22	125	11	years	year	NNS
cord-330553-sukrjl22	125	12	following	follow	VBG
cord-330553-sukrjl22	125	13	neurotropic	neurotropic	NNP
cord-330553-sukrjl22	125	14	viral	viral	JJ
cord-330553-sukrjl22	125	15	infections	infection	NNS
cord-330553-sukrjl22	125	16	and	and	CC
cord-330553-sukrjl22	125	17	studies	study	NNS
cord-330553-sukrjl22	125	18	have	have	VBP
cord-330553-sukrjl22	125	19	shown	show	VBN
cord-330553-sukrjl22	125	20	that	that	IN
cord-330553-sukrjl22	125	21	these	these	DT
cord-330553-sukrjl22	125	22	memory	memory	NN
cord-330553-sukrjl22	125	23	T	t	NN
cord-330553-sukrjl22	125	24	cells	cell	NNS
cord-330553-sukrjl22	125	25	promote	promote	VBP
cord-330553-sukrjl22	125	26	microglia	microglia	NN
cord-330553-sukrjl22	125	27	-	-	HYPH
cord-330553-sukrjl22	125	28	mediated	mediate	VBN
cord-330553-sukrjl22	125	29	synaptic	synaptic	JJ
cord-330553-sukrjl22	125	30	elimination	elimination	NN
cord-330553-sukrjl22	125	31	following	follow	VBG
cord-330553-sukrjl22	125	32	neuroinvasive	neuroinvasive	JJ
cord-330553-sukrjl22	125	33	WNV	WNV	NNP
cord-330553-sukrjl22	125	34	infections	infection	NNS
cord-330553-sukrjl22	125	35	contributing	contribute	VBG
cord-330553-sukrjl22	125	36	to	to	IN
cord-330553-sukrjl22	125	37	cognitive	cognitive	JJ
cord-330553-sukrjl22	125	38	impairment	impairment	NN
cord-330553-sukrjl22	125	39	.	.	.
cord-330553-sukrjl22	126	1	[	[	-LRB-
cord-330553-sukrjl22	126	2	83	83	CD
cord-330553-sukrjl22	126	3	,	,	,
cord-330553-sukrjl22	126	4	88	88	CD
cord-330553-sukrjl22	126	5	,	,	,
cord-330553-sukrjl22	126	6	89	89	CD
cord-330553-sukrjl22	126	7	]	]	-RRB-
cord-330553-sukrjl22	126	8	.	.	.
cord-330553-sukrjl22	127	1	A	a	DT
cord-330553-sukrjl22	127	2	recent	recent	JJ
cord-330553-sukrjl22	127	3	study	study	NN
cord-330553-sukrjl22	127	4	used	use	VBD
cord-330553-sukrjl22	127	5	a	a	DT
cord-330553-sukrjl22	127	6	mouse	mouse	NN
cord-330553-sukrjl22	127	7	model	model	NN
cord-330553-sukrjl22	127	8	of	of	IN
cord-330553-sukrjl22	127	9	viral	viral	JJ
cord-330553-sukrjl22	127	10	encephalitis	encephalitis	NN
cord-330553-sukrjl22	127	11	to	to	TO
cord-330553-sukrjl22	127	12	show	show	VB
cord-330553-sukrjl22	127	13	that	that	IN
cord-330553-sukrjl22	127	14	T	T	NNP
cord-330553-sukrjl22	127	15	cells	cell	NNS
cord-330553-sukrjl22	127	16	promote	promote	VBP
cord-330553-sukrjl22	127	17	microglia	microglia	NN
cord-330553-sukrjl22	127	18	-	-	HYPH
cord-330553-sukrjl22	127	19	mediated	mediate	VBN
cord-330553-sukrjl22	127	20	loss	loss	NN
cord-330553-sukrjl22	127	21	of	of	IN
cord-330553-sukrjl22	127	22	synapses	synapsis	NNS
cord-330553-sukrjl22	127	23	following	follow	VBG
cord-330553-sukrjl22	127	24	infection	infection	NN
cord-330553-sukrjl22	127	25	with	with	IN
cord-330553-sukrjl22	127	26	WNV	WNV	NNP
cord-330553-sukrjl22	127	27	[	[	-LRB-
cord-330553-sukrjl22	127	28	83	83	CD
cord-330553-sukrjl22	127	29	]	]	-RRB-
cord-330553-sukrjl22	127	30	.	.	.
cord-330553-sukrjl22	128	1	This	this	DT
cord-330553-sukrjl22	128	2	study	study	NN
cord-330553-sukrjl22	128	3	found	find	VBD
cord-330553-sukrjl22	128	4	an	an	DT
cord-330553-sukrjl22	128	5	increase	increase	NN
cord-330553-sukrjl22	128	6	in	in	IN
cord-330553-sukrjl22	128	7	the	the	DT
cord-330553-sukrjl22	128	8	number	number	NN
cord-330553-sukrjl22	128	9	of	of	IN
cord-330553-sukrjl22	128	10	microglia	microglia	NN
cord-330553-sukrjl22	128	11	-	-	HYPH
cord-330553-sukrjl22	128	12	expressing	express	VBG
cord-330553-sukrjl22	128	13	markers	marker	NNS
cord-330553-sukrjl22	128	14	indicative	indicative	JJ
cord-330553-sukrjl22	128	15	of	of	IN
cord-330553-sukrjl22	128	16	activation	activation	NN
cord-330553-sukrjl22	128	17	induced	induce	VBN
cord-330553-sukrjl22	128	18	by	by	IN
cord-330553-sukrjl22	128	19	the	the	DT
cord-330553-sukrjl22	128	20	T	T	NNP
cord-330553-sukrjl22	128	21	cell	cell	NN
cord-330553-sukrjl22	128	22	cytokine	cytokine	NN
cord-330553-sukrjl22	128	23	IFN	IFN	NNP
cord-330553-sukrjl22	128	24	-	-	HYPH
cord-330553-sukrjl22	128	25	γ	γ	NNP
cord-330553-sukrjl22	128	26	[	[	-LRB-
cord-330553-sukrjl22	128	27	83	83	CD
cord-330553-sukrjl22	128	28	]	]	-RRB-
cord-330553-sukrjl22	128	29	.	.	.
cord-330553-sukrjl22	129	1	Analysis	analysis	NN
cord-330553-sukrjl22	129	2	by	by	IN
cord-330553-sukrjl22	129	3	qPCR	qPCR	NNP
cord-330553-sukrjl22	129	4	also	also	RB
cord-330553-sukrjl22	129	5	revealed	reveal	VBD
cord-330553-sukrjl22	129	6	increased	increased	JJ
cord-330553-sukrjl22	129	7	expression	expression	NN
cord-330553-sukrjl22	129	8	IFN	IFN	NNP
cord-330553-sukrjl22	129	9	-	-	HYPH
cord-330553-sukrjl22	129	10	γ	γ	NNP
cord-330553-sukrjl22	129	11	in	in	IN
cord-330553-sukrjl22	129	12	the	the	DT
cord-330553-sukrjl22	129	13	hippocampus	hippocampus	NN
cord-330553-sukrjl22	129	14	following	follow	VBG
cord-330553-sukrjl22	129	15	infection	infection	NN
cord-330553-sukrjl22	129	16	and	and	CC
cord-330553-sukrjl22	129	17	throughout	throughout	IN
cord-330553-sukrjl22	129	18	recovery	recovery	NN
cord-330553-sukrjl22	129	19	.	.	.
cord-330553-sukrjl22	130	1	In	in	IN
cord-330553-sukrjl22	130	2	addition	addition	NN
cord-330553-sukrjl22	130	3	,	,	,
cord-330553-sukrjl22	130	4	mice	mouse	NNS
cord-330553-sukrjl22	130	5	deficient	deficient	JJ
cord-330553-sukrjl22	130	6	in	in	IN
cord-330553-sukrjl22	130	7	the	the	DT
cord-330553-sukrjl22	130	8	expression	expression	NN
cord-330553-sukrjl22	130	9	of	of	IN
cord-330553-sukrjl22	130	10	IFN	IFN	NNP
cord-330553-sukrjl22	130	11	-	-	HYPH
cord-330553-sukrjl22	130	12	γ	γ	NNP
cord-330553-sukrjl22	130	13	and	and	CC
cord-330553-sukrjl22	130	14	WT	WT	NNP
cord-330553-sukrjl22	130	15	mice	mouse	NNS
cord-330553-sukrjl22	130	16	were	be	VBD
cord-330553-sukrjl22	130	17	infected	infect	VBN
cord-330553-sukrjl22	130	18	with	with	IN
cord-330553-sukrjl22	130	19	WNV	WNV	NNP
cord-330553-sukrjl22	130	20	.	.	.
cord-330553-sukrjl22	131	1	Mice	mouse	NNS
cord-330553-sukrjl22	131	2	lacking	lack	VBG
cord-330553-sukrjl22	131	3	IFN	IFN	NNP
cord-330553-sukrjl22	131	4	-	-	HYPH
cord-330553-sukrjl22	131	5	γ	γ	NNP
cord-330553-sukrjl22	131	6	showed	show	VBD
cord-330553-sukrjl22	131	7	no	no	DT
cord-330553-sukrjl22	131	8	differences	difference	NNS
cord-330553-sukrjl22	131	9	in	in	IN
cord-330553-sukrjl22	131	10	survival	survival	NN
cord-330553-sukrjl22	131	11	or	or	CC
cord-330553-sukrjl22	131	12	weight	weight	NN
cord-330553-sukrjl22	131	13	loss	loss	NN
cord-330553-sukrjl22	131	14	when	when	WRB
cord-330553-sukrjl22	131	15	compared	compare	VBN
cord-330553-sukrjl22	131	16	to	to	IN
cord-330553-sukrjl22	131	17	WT	wt	NN
cord-330553-sukrjl22	131	18	mice	mouse	NNS
cord-330553-sukrjl22	131	19	[	[	-LRB-
cord-330553-sukrjl22	131	20	83	83	CD
cord-330553-sukrjl22	131	21	]	]	-RRB-
cord-330553-sukrjl22	131	22	.	.	.
cord-330553-sukrjl22	132	1	However	however	RB
cord-330553-sukrjl22	132	2	,	,	,
cord-330553-sukrjl22	132	3	WT	WT	NNP
cord-330553-sukrjl22	132	4	mice	mouse	NNS
cord-330553-sukrjl22	132	5	showed	show	VBD
cord-330553-sukrjl22	132	6	special	special	JJ
cord-330553-sukrjl22	132	7	learning	learning	NN
cord-330553-sukrjl22	132	8	deficits	deficit	NNS
cord-330553-sukrjl22	132	9	on	on	IN
cord-330553-sukrjl22	132	10	the	the	DT
cord-330553-sukrjl22	132	11	Barnes	Barnes	NNP
cord-330553-sukrjl22	132	12	maze	maze	NN
cord-330553-sukrjl22	132	13	test	test	NN
cord-330553-sukrjl22	132	14	,	,	,
cord-330553-sukrjl22	132	15	while	while	IN
cord-330553-sukrjl22	132	16	Ifngr1-/mice	ifngr1-/mice	CD
cord-330553-sukrjl22	132	17	were	be	VBD
cord-330553-sukrjl22	132	18	protected	protect	VBN
cord-330553-sukrjl22	132	19	from	from	IN
cord-330553-sukrjl22	132	20	this	this	DT
cord-330553-sukrjl22	132	21	outcome	outcome	NN
cord-330553-sukrjl22	132	22	[	[	-LRB-
cord-330553-sukrjl22	132	23	83	83	CD
cord-330553-sukrjl22	132	24	]	]	-RRB-
cord-330553-sukrjl22	132	25	.	.	.
cord-330553-sukrjl22	133	1	This	this	DT
cord-330553-sukrjl22	133	2	study	study	NN
cord-330553-sukrjl22	133	3	shows	show	VBZ
cord-330553-sukrjl22	133	4	that	that	IN
cord-330553-sukrjl22	133	5	during	during	IN
cord-330553-sukrjl22	133	6	the	the	DT
cord-330553-sukrjl22	133	7	process	process	NN
cord-330553-sukrjl22	133	8	of	of	IN
cord-330553-sukrjl22	133	9	viral	viral	JJ
cord-330553-sukrjl22	133	10	clearance	clearance	NN
cord-330553-sukrjl22	133	11	following	follow	VBG
cord-330553-sukrjl22	133	12	WNV	WNV	NNP
cord-330553-sukrjl22	133	13	infection	infection	NN
cord-330553-sukrjl22	133	14	,	,	,
cord-330553-sukrjl22	133	15	IFN	IFN	NNP
cord-330553-sukrjl22	133	16	-	-	HYPH
cord-330553-sukrjl22	133	17	γ	γ	NNP
cord-330553-sukrjl22	133	18	produced	produce	VBN
cord-330553-sukrjl22	133	19	by	by	IN
cord-330553-sukrjl22	133	20	memory	memory	NN
cord-330553-sukrjl22	133	21	T	T	NNP
cord-330553-sukrjl22	133	22	cells	cell	NNS
cord-330553-sukrjl22	133	23	can	can	MD
cord-330553-sukrjl22	133	24	alter	alter	VB
cord-330553-sukrjl22	133	25	the	the	DT
cord-330553-sukrjl22	133	26	function	function	NN
cord-330553-sukrjl22	133	27	of	of	IN
cord-330553-sukrjl22	133	28	microglia	microglia	NNP
cord-330553-sukrjl22	133	29	leading	lead	VBG
cord-330553-sukrjl22	133	30	to	to	IN
cord-330553-sukrjl22	133	31	elimination	elimination	NN
cord-330553-sukrjl22	133	32	of	of	IN
cord-330553-sukrjl22	133	33	synapses	synapsis	NNS
cord-330553-sukrjl22	133	34	.	.	.
cord-330553-sukrjl22	134	1	The	the	DT
cord-330553-sukrjl22	134	2	complement	complement	NN
cord-330553-sukrjl22	134	3	cascade	cascade	NN
cord-330553-sukrjl22	134	4	is	be	VBZ
cord-330553-sukrjl22	134	5	a	a	DT
cord-330553-sukrjl22	134	6	component	component	NN
cord-330553-sukrjl22	134	7	of	of	IN
cord-330553-sukrjl22	134	8	the	the	DT
cord-330553-sukrjl22	134	9	innate	innate	JJ
cord-330553-sukrjl22	134	10	immune	immune	JJ
cord-330553-sukrjl22	134	11	response	response	NN
cord-330553-sukrjl22	134	12	,	,	,
cord-330553-sukrjl22	134	13	which	which	WDT
cord-330553-sukrjl22	134	14	plays	play	VBZ
cord-330553-sukrjl22	134	15	a	a	DT
cord-330553-sukrjl22	134	16	key	key	JJ
cord-330553-sukrjl22	134	17	role	role	NN
cord-330553-sukrjl22	134	18	in	in	IN
cord-330553-sukrjl22	134	19	defense	defense	NN
cord-330553-sukrjl22	134	20	from	from	IN
cord-330553-sukrjl22	134	21	pathogens	pathogen	NNS
cord-330553-sukrjl22	134	22	.	.	.
cord-330553-sukrjl22	135	1	During	during	IN
cord-330553-sukrjl22	135	2	early	early	JJ
cord-330553-sukrjl22	135	3	development	development	NN
cord-330553-sukrjl22	135	4	,	,	,
cord-330553-sukrjl22	135	5	microglia	microglia	NNS
cord-330553-sukrjl22	135	6	are	be	VBP
cord-330553-sukrjl22	135	7	involved	involve	VBN
cord-330553-sukrjl22	135	8	in	in	IN
cord-330553-sukrjl22	135	9	the	the	DT
cord-330553-sukrjl22	135	10	process	process	NN
cord-330553-sukrjl22	135	11	of	of	IN
cord-330553-sukrjl22	135	12	synaptic	synaptic	JJ
cord-330553-sukrjl22	135	13	pruning	pruning	NN
cord-330553-sukrjl22	135	14	within	within	IN
cord-330553-sukrjl22	135	15	the	the	DT
cord-330553-sukrjl22	135	16	nervous	nervous	JJ
cord-330553-sukrjl22	135	17	system	system	NN
cord-330553-sukrjl22	135	18	,	,	,
cord-330553-sukrjl22	135	19	which	which	WDT
cord-330553-sukrjl22	135	20	is	be	VBZ
cord-330553-sukrjl22	135	21	dependent	dependent	JJ
cord-330553-sukrjl22	135	22	on	on	IN
cord-330553-sukrjl22	135	23	the	the	DT
cord-330553-sukrjl22	135	24	classical	classical	JJ
cord-330553-sukrjl22	135	25	complement	complement	NN
cord-330553-sukrjl22	135	26	cascade	cascade	NN
cord-330553-sukrjl22	135	27	[	[	-LRB-
cord-330553-sukrjl22	135	28	90	90	CD
cord-330553-sukrjl22	135	29	]	]	-RRB-
cord-330553-sukrjl22	135	30	[	[	-LRB-
cord-330553-sukrjl22	135	31	91	91	CD
cord-330553-sukrjl22	135	32	]	]	-RRB-
cord-330553-sukrjl22	135	33	[	[	-LRB-
cord-330553-sukrjl22	135	34	92	92	CD
cord-330553-sukrjl22	135	35	]	]	-RRB-
cord-330553-sukrjl22	136	1	[	[	-LRB-
cord-330553-sukrjl22	136	2	93	93	CD
cord-330553-sukrjl22	136	3	]	]	-RRB-
cord-330553-sukrjl22	136	4	.	.	.
cord-330553-sukrjl22	137	1	The	the	DT
cord-330553-sukrjl22	137	2	mechanism	mechanism	NN
cord-330553-sukrjl22	137	3	by	by	IN
cord-330553-sukrjl22	137	4	which	which	WDT
cord-330553-sukrjl22	137	5	the	the	DT
cord-330553-sukrjl22	137	6	IFN	IFN	NNP
cord-330553-sukrjl22	137	7	-	-	HYPH
cord-330553-sukrjl22	137	8	γ	γ	NNP
cord-330553-sukrjl22	137	9	activated	activate	VBD
cord-330553-sukrjl22	137	10	microglia	microglia	NNS
cord-330553-sukrjl22	137	11	eliminate	eliminate	VBP
cord-330553-sukrjl22	137	12	synapses	synapsis	NNS
cord-330553-sukrjl22	137	13	seems	seem	VBZ
cord-330553-sukrjl22	137	14	to	to	TO
cord-330553-sukrjl22	137	15	be	be	VB
cord-330553-sukrjl22	137	16	dependent	dependent	JJ
cord-330553-sukrjl22	137	17	on	on	IN
cord-330553-sukrjl22	137	18	the	the	DT
cord-330553-sukrjl22	137	19	complement	complement	NN
cord-330553-sukrjl22	137	20	system	system	NN
cord-330553-sukrjl22	137	21	.	.	.
cord-330553-sukrjl22	138	1	It	-PRON-	PRP
cord-330553-sukrjl22	138	2	was	be	VBD
cord-330553-sukrjl22	138	3	found	find	VBN
cord-330553-sukrjl22	138	4	that	that	IN
cord-330553-sukrjl22	138	5	brain	brain	NN
cord-330553-sukrjl22	138	6	regions	region	NNS
cord-330553-sukrjl22	138	7	retrieved	retrieve	VBD
cord-330553-sukrjl22	138	8	from	from	IN
cord-330553-sukrjl22	138	9	mice	mouse	NNS
cord-330553-sukrjl22	138	10	that	that	WDT
cord-330553-sukrjl22	138	11	had	have	VBD
cord-330553-sukrjl22	138	12	recovered	recover	VBN
cord-330553-sukrjl22	138	13	from	from	IN
cord-330553-sukrjl22	138	14	WNV	WNV	NNP
cord-330553-sukrjl22	138	15	showed	show	VBD
cord-330553-sukrjl22	138	16	increased	increased	JJ
cord-330553-sukrjl22	138	17	expression	expression	NN
cord-330553-sukrjl22	138	18	of	of	IN
cord-330553-sukrjl22	138	19	genes	gene	NNS
cord-330553-sukrjl22	138	20	involved	involve	VBN
cord-330553-sukrjl22	138	21	in	in	IN
cord-330553-sukrjl22	138	22	microglial	microglial	JJ
cord-330553-sukrjl22	138	23	synaptic	synaptic	JJ
cord-330553-sukrjl22	138	24	elimination	elimination	NN
cord-330553-sukrjl22	138	25	by	by	IN
cord-330553-sukrjl22	138	26	components	component	NNS
cord-330553-sukrjl22	138	27	of	of	IN
cord-330553-sukrjl22	138	28	the	the	DT
cord-330553-sukrjl22	138	29	complement	complement	NN
cord-330553-sukrjl22	138	30	system	system	NN
cord-330553-sukrjl22	138	31	such	such	JJ
cord-330553-sukrjl22	138	32	as	as	IN
cord-330553-sukrjl22	138	33	C1QA	C1QA	NNP
cord-330553-sukrjl22	138	34	[	[	-LRB-
cord-330553-sukrjl22	138	35	84	84	CD
cord-330553-sukrjl22	138	36	]	]	-RRB-
cord-330553-sukrjl22	138	37	.	.	.
cord-330553-sukrjl22	139	1	Mice	mouse	NNS
cord-330553-sukrjl22	139	2	with	with	IN
cord-330553-sukrjl22	139	3	either	either	CC
cord-330553-sukrjl22	139	4	fewer	few	JJR
cord-330553-sukrjl22	139	5	microglia	microglia	NNS
cord-330553-sukrjl22	139	6	(	(	-LRB-
cord-330553-sukrjl22	139	7	due	due	JJ
cord-330553-sukrjl22	139	8	to	to	IN
cord-330553-sukrjl22	139	9	lacking	lack	VBG
cord-330553-sukrjl22	139	10	the	the	DT
cord-330553-sukrjl22	139	11	CSF1R	CSF1R	NNS
cord-330553-sukrjl22	139	12	ligand	ligand	NN
cord-330553-sukrjl22	139	13	IL-34	IL-34	NNP
cord-330553-sukrjl22	139	14	)	)	-RRB-
cord-330553-sukrjl22	139	15	or	or	CC
cord-330553-sukrjl22	139	16	a	a	DT
cord-330553-sukrjl22	139	17	deficiency	deficiency	NN
cord-330553-sukrjl22	139	18	in	in	IN
cord-330553-sukrjl22	139	19	the	the	DT
cord-330553-sukrjl22	139	20	C3	C3	NNP
cord-330553-sukrjl22	139	21	complement	complement	NN
cord-330553-sukrjl22	139	22	receptor	receptor	NN
cord-330553-sukrjl22	139	23	showed	show	VBD
cord-330553-sukrjl22	139	24	increased	increase	VBN
cord-330553-sukrjl22	139	25	protection	protection	NN
cord-330553-sukrjl22	139	26	from	from	IN
cord-330553-sukrjl22	139	27	microglia	microglia	NN
cord-330553-sukrjl22	139	28	-	-	HYPH
cord-330553-sukrjl22	139	29	mediated	mediate	VBN
cord-330553-sukrjl22	139	30	synapse	synapse	NN
cord-330553-sukrjl22	139	31	elimination	elimination	NN
cord-330553-sukrjl22	139	32	[	[	-LRB-
cord-330553-sukrjl22	139	33	84	84	CD
cord-330553-sukrjl22	139	34	]	]	-RRB-
cord-330553-sukrjl22	139	35	.	.	.
cord-330553-sukrjl22	140	1	This	this	DT
cord-330553-sukrjl22	140	2	study	study	NN
cord-330553-sukrjl22	140	3	suggests	suggest	VBZ
cord-330553-sukrjl22	140	4	that	that	IN
cord-330553-sukrjl22	140	5	the	the	DT
cord-330553-sukrjl22	140	6	complement	complement	NN
cord-330553-sukrjl22	140	7	cascade	cascade	NN
cord-330553-sukrjl22	140	8	and	and	CC
cord-330553-sukrjl22	140	9	especially	especially	RB
cord-330553-sukrjl22	140	10	microglial	microglial	JJ
cord-330553-sukrjl22	140	11	-	-	HYPH
cord-330553-sukrjl22	140	12	C3	C3	NNP
cord-330553-sukrjl22	140	13	is	be	VBZ
cord-330553-sukrjl22	140	14	responsible	responsible	JJ
cord-330553-sukrjl22	140	15	for	for	IN
cord-330553-sukrjl22	140	16	synaptic	synaptic	JJ
cord-330553-sukrjl22	140	17	elimination	elimination	NN
cord-330553-sukrjl22	140	18	seen	see	VBN
cord-330553-sukrjl22	140	19	in	in	IN
cord-330553-sukrjl22	140	20	mice	mouse	NNS
cord-330553-sukrjl22	140	21	following	follow	VBG
cord-330553-sukrjl22	140	22	WNV	WNV	NNP
cord-330553-sukrjl22	140	23	infection	infection	NN
cord-330553-sukrjl22	140	24	in	in	IN
cord-330553-sukrjl22	140	25	the	the	DT
cord-330553-sukrjl22	140	26	brain	brain	NN
cord-330553-sukrjl22	140	27	.	.	.
cord-330553-sukrjl22	141	1	Collectively	collectively	RB
cord-330553-sukrjl22	141	2	,	,	,
cord-330553-sukrjl22	141	3	the	the	DT
cord-330553-sukrjl22	141	4	studies	study	NNS
cord-330553-sukrjl22	141	5	discussed	discuss	VBN
cord-330553-sukrjl22	141	6	in	in	IN
cord-330553-sukrjl22	141	7	this	this	DT
cord-330553-sukrjl22	141	8	section	section	NN
cord-330553-sukrjl22	141	9	provide	provide	VBP
cord-330553-sukrjl22	141	10	evidence	evidence	NN
cord-330553-sukrjl22	141	11	for	for	IN
cord-330553-sukrjl22	141	12	a	a	DT
cord-330553-sukrjl22	141	13	mechanism	mechanism	NN
cord-330553-sukrjl22	141	14	of	of	IN
cord-330553-sukrjl22	141	15	neuronal	neuronal	JJ
cord-330553-sukrjl22	141	16	damage	damage	NN
cord-330553-sukrjl22	141	17	following	follow	VBG
cord-330553-sukrjl22	141	18	neuroinvasive	neuroinvasive	JJ
cord-330553-sukrjl22	141	19	WNV	WNV	NNP
cord-330553-sukrjl22	141	20	infection	infection	NN
cord-330553-sukrjl22	141	21	involving	involve	VBG
cord-330553-sukrjl22	141	22	interactions	interaction	NNS
cord-330553-sukrjl22	141	23	in	in	IN
cord-330553-sukrjl22	141	24	which	which	WDT
cord-330553-sukrjl22	141	25	microglia	microglia	NNS
cord-330553-sukrjl22	141	26	are	be	VBP
cord-330553-sukrjl22	141	27	promoted	promote	VBN
cord-330553-sukrjl22	141	28	by	by	IN
cord-330553-sukrjl22	141	29	memory	memory	NN
cord-330553-sukrjl22	141	30	T	T	NNP
cord-330553-sukrjl22	141	31	cells	cell	NNS
cord-330553-sukrjl22	141	32	to	to	TO
cord-330553-sukrjl22	141	33	eliminate	eliminate	VB
cord-330553-sukrjl22	141	34	synapses	synapsis	NNS
cord-330553-sukrjl22	141	35	that	that	WDT
cord-330553-sukrjl22	141	36	have	have	VBP
cord-330553-sukrjl22	141	37	been	be	VBN
cord-330553-sukrjl22	141	38	targeted	target	VBN
cord-330553-sukrjl22	141	39	by	by	IN
cord-330553-sukrjl22	141	40	the	the	DT
cord-330553-sukrjl22	141	41	complement	complement	NN
cord-330553-sukrjl22	141	42	cascade	cascade	NN
cord-330553-sukrjl22	141	43	.	.	.
cord-330553-sukrjl22	142	1	Understanding	understand	VBG
cord-330553-sukrjl22	142	2	the	the	DT
cord-330553-sukrjl22	142	3	dynamics	dynamic	NNS
cord-330553-sukrjl22	142	4	between	between	IN
cord-330553-sukrjl22	142	5	T	t	NN
cord-330553-sukrjl22	142	6	cells	cell	NNS
cord-330553-sukrjl22	142	7	and	and	CC
cord-330553-sukrjl22	142	8	microglia	microglia	NN
cord-330553-sukrjl22	142	9	following	follow	VBG
cord-330553-sukrjl22	142	10	WNV	WNV	NNP
cord-330553-sukrjl22	142	11	infection	infection	NN
cord-330553-sukrjl22	142	12	of	of	IN
cord-330553-sukrjl22	142	13	the	the	DT
cord-330553-sukrjl22	142	14	CNS	CNS	NNP
cord-330553-sukrjl22	142	15	and	and	CC
cord-330553-sukrjl22	142	16	how	how	WRB
cord-330553-sukrjl22	142	17	microglia	microglia	NNS
cord-330553-sukrjl22	142	18	may	may	MD
cord-330553-sukrjl22	142	19	contribute	contribute	VB
cord-330553-sukrjl22	142	20	to	to	IN
cord-330553-sukrjl22	142	21	neurological	neurological	JJ
cord-330553-sukrjl22	142	22	sequalae	sequalae	NNS
cord-330553-sukrjl22	142	23	could	could	MD
cord-330553-sukrjl22	142	24	provide	provide	VB
cord-330553-sukrjl22	142	25	important	important	JJ
cord-330553-sukrjl22	142	26	insight	insight	NN
cord-330553-sukrjl22	142	27	into	into	IN
cord-330553-sukrjl22	142	28	potential	potential	JJ
cord-330553-sukrjl22	142	29	treatments	treatment	NNS
cord-330553-sukrjl22	142	30	for	for	IN
cord-330553-sukrjl22	142	31	patients	patient	NNS
cord-330553-sukrjl22	142	32	recovering	recover	VBG
cord-330553-sukrjl22	142	33	from	from	IN
cord-330553-sukrjl22	142	34	WNV	WNV	NNP
cord-330553-sukrjl22	142	35	encephalitis	encephalitis	RB
cord-330553-sukrjl22	142	36	.	.	.
cord-330553-sukrjl22	143	1	Microglia	Microglia	NNP
cord-330553-sukrjl22	143	2	maintain	maintain	VBP
cord-330553-sukrjl22	143	3	a	a	DT
cord-330553-sukrjl22	143	4	variety	variety	NN
cord-330553-sukrjl22	143	5	of	of	IN
cord-330553-sukrjl22	143	6	functions	function	NNS
cord-330553-sukrjl22	143	7	within	within	IN
cord-330553-sukrjl22	143	8	the	the	DT
cord-330553-sukrjl22	143	9	CNS	CNS	NNP
cord-330553-sukrjl22	143	10	,	,	,
cord-330553-sukrjl22	143	11	which	which	WDT
cord-330553-sukrjl22	143	12	are	be	VBP
cord-330553-sukrjl22	143	13	critical	critical	JJ
cord-330553-sukrjl22	143	14	for	for	IN
cord-330553-sukrjl22	143	15	protection	protection	NN
cord-330553-sukrjl22	143	16	from	from	IN
cord-330553-sukrjl22	143	17	pathogens	pathogen	NNS
cord-330553-sukrjl22	143	18	,	,	,
cord-330553-sukrjl22	143	19	homeostatic	homeostatic	JJ
cord-330553-sukrjl22	143	20	maintenance	maintenance	NN
cord-330553-sukrjl22	143	21	,	,	,
cord-330553-sukrjl22	143	22	and	and	CC
cord-330553-sukrjl22	143	23	early	early	JJ
cord-330553-sukrjl22	143	24	development	development	NN
cord-330553-sukrjl22	143	25	of	of	IN
cord-330553-sukrjl22	143	26	the	the	DT
cord-330553-sukrjl22	143	27	CNS	CNS	NNP
cord-330553-sukrjl22	143	28	.	.	.
cord-330553-sukrjl22	144	1	These	these	DT
cord-330553-sukrjl22	144	2	roles	role	NNS
cord-330553-sukrjl22	144	3	are	be	VBP
cord-330553-sukrjl22	144	4	summarized	summarize	VBN
cord-330553-sukrjl22	144	5	in	in	IN
cord-330553-sukrjl22	144	6	Table	Table	NNP
cord-330553-sukrjl22	144	7	1	1	CD
cord-330553-sukrjl22	144	8	.	.	.
cord-330553-sukrjl22	145	1	In	in	IN
cord-330553-sukrjl22	145	2	this	this	DT
cord-330553-sukrjl22	145	3	review	review	NN
cord-330553-sukrjl22	145	4	,	,	,
cord-330553-sukrjl22	145	5	we	-PRON-	PRP
cord-330553-sukrjl22	145	6	have	have	VBP
cord-330553-sukrjl22	145	7	highlighted	highlight	VBN
cord-330553-sukrjl22	145	8	the	the	DT
cord-330553-sukrjl22	145	9	important	important	JJ
cord-330553-sukrjl22	145	10	role	role	NN
cord-330553-sukrjl22	145	11	microglia	microglia	NN
cord-330553-sukrjl22	145	12	play	play	VBP
cord-330553-sukrjl22	145	13	during	during	IN
cord-330553-sukrjl22	145	14	a	a	DT
cord-330553-sukrjl22	145	15	neuroinvasive	neuroinvasive	JJ
cord-330553-sukrjl22	145	16	WNV	WNV	NNP
cord-330553-sukrjl22	145	17	infection	infection	NN
cord-330553-sukrjl22	145	18	.	.	.
cord-330553-sukrjl22	146	1	Although	although	IN
cord-330553-sukrjl22	146	2	it	-PRON-	PRP
cord-330553-sukrjl22	146	3	is	be	VBZ
cord-330553-sukrjl22	146	4	evident	evident	JJ
cord-330553-sukrjl22	146	5	that	that	IN
cord-330553-sukrjl22	146	6	microglia	microglia	NNS
cord-330553-sukrjl22	146	7	are	be	VBP
cord-330553-sukrjl22	146	8	essential	essential	JJ
cord-330553-sukrjl22	146	9	for	for	IN
cord-330553-sukrjl22	146	10	protection	protection	NN
cord-330553-sukrjl22	146	11	from	from	IN
cord-330553-sukrjl22	146	12	WNV	WNV	NNP
cord-330553-sukrjl22	146	13	,	,	,
cord-330553-sukrjl22	146	14	the	the	DT
cord-330553-sukrjl22	146	15	mechanism	mechanism	NN
cord-330553-sukrjl22	146	16	behind	behind	IN
cord-330553-sukrjl22	146	17	how	how	WRB
cord-330553-sukrjl22	146	18	microglia	microglia	JJ
cord-330553-sukrjl22	146	19	limit	limit	VBP
cord-330553-sukrjl22	146	20	viral	viral	JJ
cord-330553-sukrjl22	146	21	growth	growth	NN
cord-330553-sukrjl22	146	22	and	and	CC
cord-330553-sukrjl22	146	23	mortality	mortality	NN
cord-330553-sukrjl22	146	24	remains	remain	VBZ
cord-330553-sukrjl22	146	25	unclear	unclear	JJ
cord-330553-sukrjl22	146	26	.	.	.
cord-330553-sukrjl22	147	1	The	the	DT
cord-330553-sukrjl22	147	2	multiple	multiple	JJ
cord-330553-sukrjl22	147	3	and	and	CC
cord-330553-sukrjl22	147	4	complex	complex	JJ
cord-330553-sukrjl22	147	5	roles	role	NNS
cord-330553-sukrjl22	147	6	of	of	IN
cord-330553-sukrjl22	147	7	microglia	microglia	NNS
cord-330553-sukrjl22	147	8	during	during	IN
cord-330553-sukrjl22	147	9	WNV	WNV	NNP
cord-330553-sukrjl22	147	10	infections	infection	NNS
cord-330553-sukrjl22	147	11	are	be	VBP
cord-330553-sukrjl22	147	12	pictured	picture	VBN
cord-330553-sukrjl22	147	13	in	in	IN
cord-330553-sukrjl22	147	14	Figure	figure	NN
cord-330553-sukrjl22	147	15	2	2	CD
cord-330553-sukrjl22	147	16	.	.	.
cord-330553-sukrjl22	148	1	Future	future	JJ
cord-330553-sukrjl22	148	2	studies	study	NNS
cord-330553-sukrjl22	148	3	should	should	MD
cord-330553-sukrjl22	148	4	focus	focus	VB
cord-330553-sukrjl22	148	5	on	on	IN
cord-330553-sukrjl22	148	6	the	the	DT
cord-330553-sukrjl22	148	7	precise	precise	JJ
cord-330553-sukrjl22	148	8	mechanisms	mechanism	NNS
cord-330553-sukrjl22	148	9	by	by	IN
cord-330553-sukrjl22	148	10	which	which	WDT
cord-330553-sukrjl22	148	11	microglia	microglia	NN
cord-330553-sukrjl22	148	12	protect	protect	VBP
cord-330553-sukrjl22	148	13	from	from	IN
cord-330553-sukrjl22	148	14	WNV	WNV	NNP
cord-330553-sukrjl22	148	15	and	and	CC
cord-330553-sukrjl22	148	16	enhancing	enhance	VBG
cord-330553-sukrjl22	148	17	the	the	DT
cord-330553-sukrjl22	148	18	understanding	understanding	NN
cord-330553-sukrjl22	148	19	of	of	IN
cord-330553-sukrjl22	148	20	neuroinflammatory	neuroinflammatory	NN
cord-330553-sukrjl22	148	21	processes	process	NNS
cord-330553-sukrjl22	148	22	that	that	WDT
cord-330553-sukrjl22	148	23	accompany	accompany	VBP
cord-330553-sukrjl22	148	24	neuroinvasive	neuroinvasive	JJ
cord-330553-sukrjl22	148	25	WNV	WNV	NNP
cord-330553-sukrjl22	148	26	infections	infection	NNS
cord-330553-sukrjl22	148	27	.	.	.
cord-330553-sukrjl22	149	1	It	-PRON-	PRP
cord-330553-sukrjl22	149	2	still	still	RB
cord-330553-sukrjl22	149	3	remains	remain	VBZ
cord-330553-sukrjl22	149	4	to	to	TO
cord-330553-sukrjl22	149	5	be	be	VB
cord-330553-sukrjl22	149	6	determined	determine	VBN
cord-330553-sukrjl22	149	7	which	which	WDT
cord-330553-sukrjl22	149	8	cytokines	cytokine	NNS
cord-330553-sukrjl22	149	9	/	/	SYM
cord-330553-sukrjl22	149	10	chemokines	chemokine	NNS
cord-330553-sukrjl22	149	11	are	be	VBP
cord-330553-sukrjl22	149	12	produced	produce	VBN
cord-330553-sukrjl22	149	13	by	by	IN
cord-330553-sukrjl22	149	14	microglia	microglia	NNS
cord-330553-sukrjl22	149	15	during	during	IN
cord-330553-sukrjl22	149	16	a	a	DT
cord-330553-sukrjl22	149	17	WNV	WNV	NNP
cord-330553-sukrjl22	149	18	infection	infection	NN
cord-330553-sukrjl22	149	19	and	and	CC
cord-330553-sukrjl22	149	20	why	why	WRB
cord-330553-sukrjl22	149	21	a	a	DT
cord-330553-sukrjl22	149	22	decrease	decrease	NN
cord-330553-sukrjl22	149	23	in	in	IN
cord-330553-sukrjl22	149	24	the	the	DT
cord-330553-sukrjl22	149	25	expression	expression	NN
cord-330553-sukrjl22	149	26	of	of	IN
cord-330553-sukrjl22	149	27	inflammatory	inflammatory	JJ
cord-330553-sukrjl22	149	28	cytokines	cytokine	NNS
cord-330553-sukrjl22	149	29	/	/	SYM
cord-330553-sukrjl22	149	30	chemokines	chemokine	NNS
cord-330553-sukrjl22	149	31	in	in	IN
cord-330553-sukrjl22	149	32	not	not	RB
cord-330553-sukrjl22	149	33	observed	observe	VBN
cord-330553-sukrjl22	149	34	in	in	IN
cord-330553-sukrjl22	149	35	the	the	DT
cord-330553-sukrjl22	149	36	CNS	CNS	NNP
cord-330553-sukrjl22	149	37	of	of	IN
cord-330553-sukrjl22	149	38	mice	mouse	NNS
cord-330553-sukrjl22	149	39	following	follow	VBG
cord-330553-sukrjl22	149	40	WNV	WNV	NNP
cord-330553-sukrjl22	149	41	infection	infection	NN
cord-330553-sukrjl22	149	42	in	in	IN
cord-330553-sukrjl22	149	43	the	the	DT
cord-330553-sukrjl22	149	44	presence	presence	NN
cord-330553-sukrjl22	149	45	of	of	IN
cord-330553-sukrjl22	149	46	PLX5622	PLX5622	NNP
cord-330553-sukrjl22	149	47	.	.	.
cord-330553-sukrjl22	150	1	which	which	WDT
cord-330553-sukrjl22	150	2	may	may	MD
cord-330553-sukrjl22	150	3	lead	lead	VB
cord-330553-sukrjl22	150	4	to	to	IN
cord-330553-sukrjl22	150	5	altered	altered	JJ
cord-330553-sukrjl22	150	6	outcomes	outcome	NNS
cord-330553-sukrjl22	150	7	when	when	WRB
cord-330553-sukrjl22	150	8	comparing	compare	VBG
cord-330553-sukrjl22	150	9	human	human	NN
cord-330553-sukrjl22	150	10	and	and	CC
cord-330553-sukrjl22	150	11	mouse	mouse	NN
cord-330553-sukrjl22	150	12	infections	infection	NNS
cord-330553-sukrjl22	150	13	[	[	-LRB-
cord-330553-sukrjl22	150	14	96	96	CD
cord-330553-sukrjl22	150	15	]	]	-RRB-
cord-330553-sukrjl22	150	16	.	.	.
cord-330553-sukrjl22	151	1	It	-PRON-	PRP
cord-330553-sukrjl22	151	2	is	be	VBZ
cord-330553-sukrjl22	151	3	vital	vital	JJ
cord-330553-sukrjl22	151	4	to	to	IN
cord-330553-sukrjl22	151	5	the	the	DT
cord-330553-sukrjl22	151	6	complete	complete	JJ
cord-330553-sukrjl22	151	7	understanding	understanding	NN
cord-330553-sukrjl22	151	8	of	of	IN
cord-330553-sukrjl22	151	9	the	the	DT
cord-330553-sukrjl22	151	10	role	role	NN
cord-330553-sukrjl22	151	11	of	of	IN
cord-330553-sukrjl22	151	12	microglia	microglia	NNP
cord-330553-sukrjl22	151	13	during	during	IN
cord-330553-sukrjl22	151	14	a	a	DT
cord-330553-sukrjl22	151	15	WNV	WNV	NNP
cord-330553-sukrjl22	151	16	infection	infection	NN
cord-330553-sukrjl22	151	17	to	to	TO
cord-330553-sukrjl22	151	18	use	use	VB
cord-330553-sukrjl22	151	19	mouse	mouse	NN
cord-330553-sukrjl22	151	20	studies	study	NNS
cord-330553-sukrjl22	151	21	as	as	IN
cord-330553-sukrjl22	151	22	a	a	DT
cord-330553-sukrjl22	151	23	compliment	compliment	NN
cord-330553-sukrjl22	151	24	to	to	IN
cord-330553-sukrjl22	151	25	human	human	JJ
cord-330553-sukrjl22	151	26	studies	study	NNS
cord-330553-sukrjl22	151	27	and	and	CC
cord-330553-sukrjl22	151	28	not	not	RB
cord-330553-sukrjl22	151	29	a	a	DT
cord-330553-sukrjl22	151	30	replacement	replacement	NN
cord-330553-sukrjl22	151	31	.	.	.
cord-330553-sukrjl22	152	1	Understanding	understand	VBG
cord-330553-sukrjl22	152	2	exactly	exactly	RB
cord-330553-sukrjl22	152	3	how	how	WRB
cord-330553-sukrjl22	152	4	microglia	microglia	JJ
cord-330553-sukrjl22	152	5	influence	influence	NN
cord-330553-sukrjl22	153	1	the	the	DT
cord-330553-sukrjl22	153	2	progression	progression	NN
cord-330553-sukrjl22	153	3	and	and	CC
cord-330553-sukrjl22	153	4	recovery	recovery	NN
cord-330553-sukrjl22	153	5	of	of	IN
cord-330553-sukrjl22	153	6	WNV	WNV	NNP
cord-330553-sukrjl22	153	7	neuroinvasive	neuroinvasive	JJ
cord-330553-sukrjl22	153	8	infections	infection	NNS
cord-330553-sukrjl22	153	9	will	will	MD
cord-330553-sukrjl22	153	10	allow	allow	VB
cord-330553-sukrjl22	153	11	for	for	IN
cord-330553-sukrjl22	153	12	the	the	DT
cord-330553-sukrjl22	153	13	development	development	NN
cord-330553-sukrjl22	153	14	of	of	IN
cord-330553-sukrjl22	153	15	specific	specific	JJ
cord-330553-sukrjl22	153	16	treatments	treatment	NNS
cord-330553-sukrjl22	153	17	,	,	,
cord-330553-sukrjl22	153	18	which	which	WDT
cord-330553-sukrjl22	153	19	could	could	MD
cord-330553-sukrjl22	153	20	provide	provide	VB
cord-330553-sukrjl22	153	21	the	the	DT
cord-330553-sukrjl22	153	22	optimal	optimal	JJ
cord-330553-sukrjl22	153	23	outcome	outcome	NN
cord-330553-sukrjl22	153	24	to	to	IN
cord-330553-sukrjl22	153	25	patients	patient	NNS
cord-330553-sukrjl22	153	26	recovering	recover	VBG
cord-330553-sukrjl22	153	27	from	from	IN
cord-330553-sukrjl22	153	28	this	this	DT
cord-330553-sukrjl22	153	29	infection	infection	NN
cord-330553-sukrjl22	153	30	.	.	.
cord-330553-sukrjl22	154	1	[	[	-LRB-
cord-330553-sukrjl22	154	2	3	3	CD
cord-330553-sukrjl22	154	3	]	]	-RRB-
cord-330553-sukrjl22	154	4	.	.	.
cord-330553-sukrjl22	155	1	Activated	activate	VBN
cord-330553-sukrjl22	155	2	microglia	microglia	NN
cord-330553-sukrjl22	155	3	control	control	VBP
cord-330553-sukrjl22	155	4	viral	viral	JJ
cord-330553-sukrjl22	155	5	growth	growth	NN
cord-330553-sukrjl22	155	6	and	and	CC
cord-330553-sukrjl22	155	7	reduce	reduce	VB
cord-330553-sukrjl22	155	8	mortality	mortality	NN
cord-330553-sukrjl22	155	9	in	in	IN
cord-330553-sukrjl22	155	10	mice	mouse	NNS
cord-330553-sukrjl22	155	11	infected	infect	VBN
cord-330553-sukrjl22	155	12	with	with	IN
cord-330553-sukrjl22	155	13	WNV	WNV	NNP
cord-330553-sukrjl22	155	14	[	[	-LRB-
cord-330553-sukrjl22	155	15	4	4	CD
cord-330553-sukrjl22	155	16	]	]	-RRB-
cord-330553-sukrjl22	155	17	,	,	,
cord-330553-sukrjl22	155	18	likely	likely	RB
cord-330553-sukrjl22	155	19	due	due	IN
cord-330553-sukrjl22	155	20	to	to	IN
cord-330553-sukrjl22	155	21	a	a	DT
cord-330553-sukrjl22	155	22	combination	combination	NN
cord-330553-sukrjl22	155	23	of	of	IN
cord-330553-sukrjl22	155	24	microglial	microglial	JJ
cord-330553-sukrjl22	155	25	phagocytosis	phagocytosis	NN
cord-330553-sukrjl22	155	26	of	of	IN
cord-330553-sukrjl22	155	27	infected	infected	JJ
cord-330553-sukrjl22	155	28	neurons	neuron	NNS
cord-330553-sukrjl22	155	29	and	and	CC
cord-330553-sukrjl22	155	30	the	the	DT
cord-330553-sukrjl22	155	31	release	release	NN
cord-330553-sukrjl22	155	32	of	of	IN
cord-330553-sukrjl22	155	33	inflammatory	inflammatory	JJ
cord-330553-sukrjl22	155	34	cytokines	cytokine	NNS
cord-330553-sukrjl22	155	35	,	,	,
cord-330553-sukrjl22	155	36	which	which	WDT
cord-330553-sukrjl22	155	37	contribute	contribute	VBP
cord-330553-sukrjl22	155	38	to	to	IN
cord-330553-sukrjl22	155	39	neuroinflammation	neuroinflammation	NN
cord-330553-sukrjl22	155	40	and	and	CC
cord-330553-sukrjl22	155	41	the	the	DT
cord-330553-sukrjl22	155	42	recruitment	recruitment	NN
cord-330553-sukrjl22	155	43	of	of	IN
cord-330553-sukrjl22	155	44	lymphocytes	lymphocyte	NNS
cord-330553-sukrjl22	155	45	[	[	-LRB-
cord-330553-sukrjl22	155	46	3	3	CD
cord-330553-sukrjl22	155	47	,	,	,
cord-330553-sukrjl22	155	48	5	5	CD
cord-330553-sukrjl22	155	49	]	]	-RRB-
cord-330553-sukrjl22	155	50	.	.	.
cord-330553-sukrjl22	156	1	In	in	IN
cord-330553-sukrjl22	156	2	some	some	DT
cord-330553-sukrjl22	156	3	cases	case	NNS
cord-330553-sukrjl22	156	4	,	,	,
cord-330553-sukrjl22	156	5	released	release	VBN
cord-330553-sukrjl22	156	6	cytokines	cytokine	NNS
cord-330553-sukrjl22	156	7	may	may	MD
cord-330553-sukrjl22	156	8	contribute	contribute	VB
cord-330553-sukrjl22	156	9	to	to	IN
cord-330553-sukrjl22	156	10	WNV	WNV	NNP
cord-330553-sukrjl22	156	11	-	-	HYPH
cord-330553-sukrjl22	156	12	induced	induce	VBN
cord-330553-sukrjl22	156	13	pathogenesis	pathogenesis	NN
cord-330553-sukrjl22	156	14	.	.	.
cord-330553-sukrjl22	157	1	MMP9	MMP9	NNP
cord-330553-sukrjl22	157	2	and	and	CC
cord-330553-sukrjl22	157	3	ICAM-1	icam-1	JJ
cord-330553-sukrjl22	157	4	expression	expression	NN
cord-330553-sukrjl22	157	5	by	by	IN
cord-330553-sukrjl22	157	6	microglia	microglia	NNS
cord-330553-sukrjl22	157	7	may	may	MD
cord-330553-sukrjl22	157	8	enhance	enhance	VB
cord-330553-sukrjl22	157	9	viral	viral	JJ
cord-330553-sukrjl22	157	10	entry	entry	NN
cord-330553-sukrjl22	157	11	into	into	IN
cord-330553-sukrjl22	157	12	the	the	DT
cord-330553-sukrjl22	157	13	CNS	CNS	NNP
cord-330553-sukrjl22	157	14	through	through	IN
cord-330553-sukrjl22	157	15	breakdown	breakdown	NN
cord-330553-sukrjl22	157	16	of	of	IN
cord-330553-sukrjl22	157	17	the	the	DT
cord-330553-sukrjl22	157	18	BBB	BBB	NNP
cord-330553-sukrjl22	157	19	and	and	CC
cord-330553-sukrjl22	157	20	extravasation	extravasation	NN
cord-330553-sukrjl22	157	21	of	of	IN
cord-330553-sukrjl22	157	22	potentially	potentially	RB
cord-330553-sukrjl22	157	23	infected	infected	JJ
cord-330553-sukrjl22	157	24	leukocytes	leukocyte	NNS
cord-330553-sukrjl22	157	25	[	[	-LRB-
cord-330553-sukrjl22	157	26	6	6	CD
cord-330553-sukrjl22	157	27	,	,	,
cord-330553-sukrjl22	157	28	7	7	CD
cord-330553-sukrjl22	157	29	]	]	-RRB-
cord-330553-sukrjl22	157	30	.	.	.
cord-330553-sukrjl22	158	1	LONG	long	JJ
cord-330553-sukrjl22	158	2	TERM	term	NN
cord-330553-sukrjl22	158	3	EFFECTS	effects	NN
cord-330553-sukrjl22	158	4	:	:	:
cord-330553-sukrjl22	159	1	Following	follow	VBG
cord-330553-sukrjl22	159	2	infiltration	infiltration	NN
cord-330553-sukrjl22	159	3	of	of	IN
cord-330553-sukrjl22	159	4	T	t	NN
cord-330553-sukrjl22	159	5	cells	cell	NNS
cord-330553-sukrjl22	159	6	into	into	IN
cord-330553-sukrjl22	159	7	the	the	DT
cord-330553-sukrjl22	159	8	CNS	CNS	NNP
cord-330553-sukrjl22	159	9	,	,	,
cord-330553-sukrjl22	159	10	microglia	microglia	NNS
cord-330553-sukrjl22	159	11	may	may	MD
cord-330553-sukrjl22	159	12	contribute	contribute	VB
cord-330553-sukrjl22	159	13	to	to	IN
cord-330553-sukrjl22	159	14	synaptic	synaptic	JJ
cord-330553-sukrjl22	159	15	damage	damage	NN
cord-330553-sukrjl22	159	16	triggered	trigger	VBN
cord-330553-sukrjl22	159	17	by	by	IN
cord-330553-sukrjl22	159	18	IFNγ	IFNγ	NNS
cord-330553-sukrjl22	159	19	produced	produce	VBN
cord-330553-sukrjl22	159	20	by	by	IN
cord-330553-sukrjl22	159	21	memory	memory	NN
cord-330553-sukrjl22	159	22	CD8	CD8	NNP
cord-330553-sukrjl22	159	23	+	+	CC
cord-330553-sukrjl22	159	24	T	T	NNP
cord-330553-sukrjl22	159	25	cells	cell	NNS
cord-330553-sukrjl22	159	26	and	and	CC
cord-330553-sukrjl22	159	27	enhanced	enhance	VBN
cord-330553-sukrjl22	159	28	by	by	IN
cord-330553-sukrjl22	159	29	the	the	DT
cord-330553-sukrjl22	159	30	complement	complement	NN
cord-330553-sukrjl22	159	31	cascade	cascade	NN
cord-330553-sukrjl22	159	32	[	[	-LRB-
cord-330553-sukrjl22	159	33	8	8	CD
cord-330553-sukrjl22	159	34	,	,	,
cord-330553-sukrjl22	159	35	9	9	CD
cord-330553-sukrjl22	159	36	]	]	-RRB-
cord-330553-sukrjl22	159	37	.	.	.
cord-330553-sukrjl22	160	1	This	this	DT
cord-330553-sukrjl22	160	2	synaptic	synaptic	JJ
cord-330553-sukrjl22	160	3	elimination	elimination	NN
cord-330553-sukrjl22	160	4	leads	lead	VBZ
cord-330553-sukrjl22	160	5	to	to	IN
cord-330553-sukrjl22	160	6	neurological	neurological	JJ
cord-330553-sukrjl22	160	7	damage	damage	NN
cord-330553-sukrjl22	160	8	during	during	IN
cord-330553-sukrjl22	160	9	recovery	recovery	NN
cord-330553-sukrjl22	160	10	from	from	IN
cord-330553-sukrjl22	160	11	WNV	WNV	NNP
cord-330553-sukrjl22	160	12	encephalitis	encephalitis	RB
cord-330553-sukrjl22	160	13	[	[	-LRB-
cord-330553-sukrjl22	160	14	9	9	CD
cord-330553-sukrjl22	160	15	]	]	-RRB-
cord-330553-sukrjl22	160	16	.	.	.
cord-330553-sukrjl22	161	1	Green	Green	NNP
cord-330553-sukrjl22	161	2	and	and	CC
cord-330553-sukrjl22	161	3	Red	red	JJ
cord-330553-sukrjl22	161	4	indicator	indicator	NN
cord-330553-sukrjl22	161	5	arrows	arrow	NNS
cord-330553-sukrjl22	161	6	designate	designate	VBP
cord-330553-sukrjl22	161	7	protective	protective	JJ
cord-330553-sukrjl22	161	8	(	(	-LRB-
cord-330553-sukrjl22	161	9	green	green	JJ
cord-330553-sukrjl22	161	10	)	)	-RRB-
cord-330553-sukrjl22	161	11	and	and	CC
cord-330553-sukrjl22	161	12	non	non	JJ
cord-330553-sukrjl22	161	13	-	-	JJ
cord-330553-sukrjl22	161	14	protective	protective	JJ
cord-330553-sukrjl22	161	15	(	(	-LRB-
cord-330553-sukrjl22	161	16	red	red	JJ
cord-330553-sukrjl22	161	17	)	)	-RRB-
cord-330553-sukrjl22	161	18	microglial	microglial	JJ
cord-330553-sukrjl22	161	19	responses	response	NNS
cord-330553-sukrjl22	161	20	.	.	.
cord-330553-sukrjl22	162	1	[	[	-LRB-
cord-330553-sukrjl22	162	2	83	83	CD
cord-330553-sukrjl22	162	3	,	,	,
cord-330553-sukrjl22	162	4	84	84	CD
cord-330553-sukrjl22	162	5	]	]	-RRB-
cord-330553-sukrjl22	163	1	While	while	IN
cord-330553-sukrjl22	163	2	microglia	microglia	NNS
cord-330553-sukrjl22	163	3	are	be	VBP
cord-330553-sukrjl22	163	4	protective	protective	JJ
cord-330553-sukrjl22	163	5	during	during	IN
cord-330553-sukrjl22	163	6	the	the	DT
cord-330553-sukrjl22	163	7	initial	initial	JJ
cord-330553-sukrjl22	163	8	infection	infection	NN
cord-330553-sukrjl22	163	9	and	and	CC
cord-330553-sukrjl22	163	10	vital	vital	JJ
cord-330553-sukrjl22	163	11	for	for	IN
cord-330553-sukrjl22	163	12	resolution	resolution	NN
cord-330553-sukrjl22	163	13	of	of	IN
cord-330553-sukrjl22	163	14	the	the	DT
cord-330553-sukrjl22	163	15	infection	infection	NN
cord-330553-sukrjl22	163	16	,	,	,
cord-330553-sukrjl22	163	17	potentially	potentially	RB
cord-330553-sukrjl22	163	18	dysregulated	dysregulate	VBN
cord-330553-sukrjl22	163	19	microglia	microglia	JJ
cord-330553-sukrjl22	163	20	responses	response	NNS
cord-330553-sukrjl22	163	21	driven	drive	VBN
cord-330553-sukrjl22	163	22	by	by	IN
cord-330553-sukrjl22	163	23	T	T	NNP
cord-330553-sukrjl22	163	24	cells	cell	NNS
cord-330553-sukrjl22	163	25	may	may	MD
cord-330553-sukrjl22	163	26	contribute	contribute	VB
cord-330553-sukrjl22	163	27	to	to	IN
cord-330553-sukrjl22	163	28	neurological	neurological	JJ
cord-330553-sukrjl22	163	29	damage	damage	NN
cord-330553-sukrjl22	163	30	and	and	CC
cord-330553-sukrjl22	163	31	long	long	JJ
cord-330553-sukrjl22	163	32	-	-	HYPH
cord-330553-sukrjl22	163	33	term	term	NN
cord-330553-sukrjl22	163	34	impairment	impairment	NN
cord-330553-sukrjl22	163	35	during	during	IN
cord-330553-sukrjl22	163	36	the	the	DT
cord-330553-sukrjl22	163	37	recovery	recovery	NN
cord-330553-sukrjl22	163	38	stages	stage	NNS
cord-330553-sukrjl22	163	39	.	.	.
cord-330553-sukrjl22	164	1	Targeting	target	VBG
cord-330553-sukrjl22	164	2	microglial	microglial	JJ
cord-330553-sukrjl22	164	3	responses	response	NNS
cord-330553-sukrjl22	164	4	during	during	IN
cord-330553-sukrjl22	164	5	both	both	CC
cord-330553-sukrjl22	164	6	the	the	DT
cord-330553-sukrjl22	164	7	initial	initial	JJ
cord-330553-sukrjl22	164	8	and	and	CC
cord-330553-sukrjl22	164	9	late	late	JJ
cord-330553-sukrjl22	164	10	stages	stage	NNS
cord-330553-sukrjl22	164	11	of	of	IN
cord-330553-sukrjl22	164	12	infections	infection	NNS
cord-330553-sukrjl22	164	13	may	may	MD
cord-330553-sukrjl22	164	14	offer	offer	VB
cord-330553-sukrjl22	164	15	new	new	JJ
cord-330553-sukrjl22	164	16	therapeutic	therapeutic	JJ
cord-330553-sukrjl22	164	17	options	option	NNS
cord-330553-sukrjl22	164	18	for	for	IN
cord-330553-sukrjl22	164	19	human	human	JJ
cord-330553-sukrjl22	164	20	patients	patient	NNS
cord-330553-sukrjl22	164	21	with	with	IN
cord-330553-sukrjl22	164	22	neuroinvasive	neuroinvasive	JJ
cord-330553-sukrjl22	164	23	WNV	WNV	NNP
cord-330553-sukrjl22	164	24	infections	infection	NNS
cord-330553-sukrjl22	164	25	.	.	.
cord-330553-sukrjl22	165	1	For	for	IN
cord-330553-sukrjl22	165	2	example	example	NN
cord-330553-sukrjl22	165	3	,	,	,
cord-330553-sukrjl22	165	4	it	-PRON-	PRP
cord-330553-sukrjl22	165	5	may	may	MD
cord-330553-sukrjl22	165	6	be	be	VB
cord-330553-sukrjl22	165	7	beneficial	beneficial	JJ
cord-330553-sukrjl22	165	8	to	to	TO
cord-330553-sukrjl22	165	9	enhance	enhance	VB
cord-330553-sukrjl22	165	10	the	the	DT
cord-330553-sukrjl22	165	11	activity	activity	NN
cord-330553-sukrjl22	165	12	of	of	IN
cord-330553-sukrjl22	165	13	microglia	microglia	NN
cord-330553-sukrjl22	165	14	during	during	IN
cord-330553-sukrjl22	165	15	the	the	DT
cord-330553-sukrjl22	165	16	initial	initial	JJ
cord-330553-sukrjl22	165	17	infection	infection	NN
cord-330553-sukrjl22	165	18	to	to	TO
cord-330553-sukrjl22	165	19	provide	provide	VB
cord-330553-sukrjl22	165	20	enhanced	enhanced	JJ
cord-330553-sukrjl22	165	21	protection	protection	NN
cord-330553-sukrjl22	165	22	but	but	CC
cord-330553-sukrjl22	165	23	then	then	RB
cord-330553-sukrjl22	165	24	limit	limit	VB
cord-330553-sukrjl22	165	25	microglial	microglial	JJ
cord-330553-sukrjl22	165	26	activation	activation	NN
cord-330553-sukrjl22	165	27	during	during	IN
cord-330553-sukrjl22	165	28	the	the	DT
cord-330553-sukrjl22	165	29	recovery	recovery	NN
cord-330553-sukrjl22	165	30	stages	stage	NNS
cord-330553-sukrjl22	165	31	of	of	IN
cord-330553-sukrjl22	165	32	infection	infection	NN
cord-330553-sukrjl22	165	33	to	to	TO
cord-330553-sukrjl22	165	34	improve	improve	VB
cord-330553-sukrjl22	165	35	long	long	JJ
cord-330553-sukrjl22	165	36	-	-	HYPH
cord-330553-sukrjl22	165	37	term	term	NN
cord-330553-sukrjl22	165	38	outcomes	outcome	NNS
cord-330553-sukrjl22	165	39	.	.	.
cord-330553-sukrjl22	166	1	One	one	CD
cord-330553-sukrjl22	166	2	promising	promising	JJ
cord-330553-sukrjl22	166	3	treatment	treatment	NN
cord-330553-sukrjl22	166	4	that	that	WDT
cord-330553-sukrjl22	166	5	may	may	MD
cord-330553-sukrjl22	166	6	be	be	VB
cord-330553-sukrjl22	166	7	used	use	VBN
cord-330553-sukrjl22	166	8	during	during	IN
cord-330553-sukrjl22	166	9	the	the	DT
cord-330553-sukrjl22	166	10	initial	initial	JJ
cord-330553-sukrjl22	166	11	WNV	WNV	NNP
cord-330553-sukrjl22	166	12	infection	infection	NN
cord-330553-sukrjl22	166	13	to	to	TO
cord-330553-sukrjl22	166	14	improve	improve	VB
cord-330553-sukrjl22	166	15	survival	survival	NN
cord-330553-sukrjl22	166	16	is	be	VBZ
cord-330553-sukrjl22	166	17	the	the	DT
cord-330553-sukrjl22	166	18	use	use	NN
cord-330553-sukrjl22	166	19	of	of	IN
cord-330553-sukrjl22	166	20	granulocyte	granulocyte	NN
cord-330553-sukrjl22	166	21	-	-	HYPH
cord-330553-sukrjl22	166	22	macrophage	macrophage	NN
cord-330553-sukrjl22	166	23	colony	colony	NN
cord-330553-sukrjl22	166	24	-	-	HYPH
cord-330553-sukrjl22	166	25	stimulating	stimulate	VBG
cord-330553-sukrjl22	166	26	factor	factor	NN
cord-330553-sukrjl22	166	27	(	(	-LRB-
cord-330553-sukrjl22	166	28	GM	GM	NNP
cord-330553-sukrjl22	166	29	-	-	HYPH
cord-330553-sukrjl22	166	30	CSF	CSF	NNP
cord-330553-sukrjl22	166	31	)	)	-RRB-
cord-330553-sukrjl22	166	32	,	,	,
cord-330553-sukrjl22	166	33	which	which	WDT
cord-330553-sukrjl22	166	34	promotes	promote	VBZ
cord-330553-sukrjl22	166	35	growth	growth	NN
cord-330553-sukrjl22	166	36	and	and	CC
cord-330553-sukrjl22	166	37	activation	activation	NN
cord-330553-sukrjl22	166	38	of	of	IN
cord-330553-sukrjl22	166	39	microglia	microglia	NN
cord-330553-sukrjl22	166	40	,	,	,
cord-330553-sukrjl22	166	41	macrophages	macrophage	NNS
cord-330553-sukrjl22	166	42	,	,	,
cord-330553-sukrjl22	166	43	and	and	CC
cord-330553-sukrjl22	166	44	other	other	JJ
cord-330553-sukrjl22	166	45	myeloid	myeloid	NN
cord-330553-sukrjl22	166	46	cells	cell	NNS
cord-330553-sukrjl22	166	47	[	[	-LRB-
cord-330553-sukrjl22	166	48	75	75	CD
cord-330553-sukrjl22	166	49	,	,	,
cord-330553-sukrjl22	166	50	94	94	CD
cord-330553-sukrjl22	166	51	]	]	-RRB-
cord-330553-sukrjl22	166	52	.	.	.
cord-330553-sukrjl22	167	1	This	this	DT
cord-330553-sukrjl22	167	2	drug	drug	NN
cord-330553-sukrjl22	167	3	is	be	VBZ
cord-330553-sukrjl22	167	4	currently	currently	RB
cord-330553-sukrjl22	167	5	available	available	JJ
cord-330553-sukrjl22	167	6	(	(	-LRB-
cord-330553-sukrjl22	167	7	Leukine	Leukine	NNP
cord-330553-sukrjl22	167	8	)	)	-RRB-
cord-330553-sukrjl22	167	9	and	and	CC
cord-330553-sukrjl22	167	10	is	be	VBZ
cord-330553-sukrjl22	167	11	used	use	VBN
cord-330553-sukrjl22	167	12	to	to	TO
cord-330553-sukrjl22	167	13	treat	treat	VB
cord-330553-sukrjl22	167	14	leucopenic	leucopenic	JJ
cord-330553-sukrjl22	167	15	patients	patient	NNS
cord-330553-sukrjl22	167	16	as	as	RB
cord-330553-sukrjl22	167	17	well	well	RB
cord-330553-sukrjl22	167	18	as	as	IN
cord-330553-sukrjl22	167	19	being	be	VBG
cord-330553-sukrjl22	167	20	investigated	investigate	VBN
cord-330553-sukrjl22	167	21	as	as	IN
cord-330553-sukrjl22	167	22	a	a	DT
cord-330553-sukrjl22	167	23	treatment	treatment	NN
cord-330553-sukrjl22	167	24	for	for	IN
cord-330553-sukrjl22	167	25	Alzheimer	Alzheimer	NNP
cord-330553-sukrjl22	167	26	's	's	POS
cord-330553-sukrjl22	167	27	disease	disease	NN
cord-330553-sukrjl22	167	28	[	[	-LRB-
cord-330553-sukrjl22	167	29	95	95	CD
cord-330553-sukrjl22	167	30	]	]	-RRB-
cord-330553-sukrjl22	167	31	.	.	.
cord-330553-sukrjl22	168	1	Another	another	DT
cord-330553-sukrjl22	168	2	study	study	NN
cord-330553-sukrjl22	168	3	showed	show	VBD
cord-330553-sukrjl22	168	4	that	that	IN
cord-330553-sukrjl22	168	5	the	the	DT
cord-330553-sukrjl22	168	6	anti	anti	JJ
cord-330553-sukrjl22	168	7	-	-	JJ
cord-330553-sukrjl22	168	8	inflammatory	inflammatory	JJ
cord-330553-sukrjl22	168	9	drug	drug	NN
cord-330553-sukrjl22	168	10	minocycline	minocycline	NNP
cord-330553-sukrjl22	168	11	may	may	MD
cord-330553-sukrjl22	168	12	be	be	VB
cord-330553-sukrjl22	168	13	beneficial	beneficial	JJ
cord-330553-sukrjl22	168	14	in	in	IN
cord-330553-sukrjl22	168	15	recovery	recovery	NN
cord-330553-sukrjl22	168	16	from	from	IN
cord-330553-sukrjl22	168	17	a	a	DT
cord-330553-sukrjl22	168	18	WNV	WNV	NNP
cord-330553-sukrjl22	168	19	infection	infection	NN
cord-330553-sukrjl22	168	20	of	of	IN
cord-330553-sukrjl22	168	21	the	the	DT
cord-330553-sukrjl22	168	22	CNS	CNS	NNP
cord-330553-sukrjl22	168	23	[	[	-LRB-
cord-330553-sukrjl22	168	24	42	42	CD
cord-330553-sukrjl22	168	25	]	]	-RRB-
cord-330553-sukrjl22	168	26	.	.	.
cord-330553-sukrjl22	169	1	Most	Most	JJS
cord-330553-sukrjl22	169	2	of	of	IN
cord-330553-sukrjl22	169	3	the	the	DT
cord-330553-sukrjl22	169	4	studies	study	NNS
cord-330553-sukrjl22	169	5	presented	present	VBN
cord-330553-sukrjl22	169	6	in	in	IN
cord-330553-sukrjl22	169	7	this	this	DT
cord-330553-sukrjl22	169	8	review	review	NN
cord-330553-sukrjl22	169	9	utilized	utilize	VBD
cord-330553-sukrjl22	169	10	a	a	DT
cord-330553-sukrjl22	169	11	knockout	knockout	NN
cord-330553-sukrjl22	169	12	mouse	mouse	NN
cord-330553-sukrjl22	169	13	model	model	NN
cord-330553-sukrjl22	169	14	or	or	CC
cord-330553-sukrjl22	169	15	mouse	mouse	NN
cord-330553-sukrjl22	169	16	tissue	tissue	NN
cord-330553-sukrjl22	169	17	model	model	NN
cord-330553-sukrjl22	169	18	to	to	TO
cord-330553-sukrjl22	169	19	investigate	investigate	VB
cord-330553-sukrjl22	169	20	microglia	microglia	NNS
cord-330553-sukrjl22	169	21	.	.	.
cord-330553-sukrjl22	170	1	However	however	RB
cord-330553-sukrjl22	170	2	,	,	,
cord-330553-sukrjl22	170	3	it	-PRON-	PRP
cord-330553-sukrjl22	170	4	is	be	VBZ
cord-330553-sukrjl22	170	5	important	important	JJ
cord-330553-sukrjl22	170	6	to	to	TO
cord-330553-sukrjl22	170	7	understand	understand	VB
cord-330553-sukrjl22	170	8	the	the	DT
cord-330553-sukrjl22	170	9	limitations	limitation	NNS
cord-330553-sukrjl22	170	10	of	of	IN
cord-330553-sukrjl22	170	11	using	use	VBG
cord-330553-sukrjl22	170	12	mouse	mouse	NN
cord-330553-sukrjl22	170	13	models	model	NNS
cord-330553-sukrjl22	170	14	when	when	WRB
cord-330553-sukrjl22	170	15	studying	study	VBG
cord-330553-sukrjl22	170	16	microglia	microglia	NNS
cord-330553-sukrjl22	170	17	and	and	CC
cord-330553-sukrjl22	170	18	WNV	WNV	NNP
cord-330553-sukrjl22	170	19	pathology	pathology	NN
cord-330553-sukrjl22	170	20	.	.	.
cord-330553-sukrjl22	171	1	Human	human	JJ
cord-330553-sukrjl22	171	2	microglia	microglia	NNS
cord-330553-sukrjl22	171	3	exhibit	exhibit	VBP
cord-330553-sukrjl22	171	4	several	several	JJ
cord-330553-sukrjl22	171	5	differences	difference	NNS
cord-330553-sukrjl22	171	6	to	to	TO
cord-330553-sukrjl22	171	7	mouse	mouse	VB
cord-330553-sukrjl22	171	8	microglia	microglia	NNS
cord-330553-sukrjl22	171	9	including	include	VBG
cord-330553-sukrjl22	171	10	increased	increase	VBN
cord-330553-sukrjl22	171	11	levels	level	NNS
cord-330553-sukrjl22	171	12	of	of	IN
cord-330553-sukrjl22	171	13	several	several	JJ
cord-330553-sukrjl22	171	14	immune	immune	JJ
cord-330553-sukrjl22	171	15	genes	gene	NNS
cord-330553-sukrjl22	171	16	and	and	CC
cord-330553-sukrjl22	171	17	being	be	VBG
cord-330553-sukrjl22	171	18	longer	long	RBR
cord-330553-sukrjl22	171	19	-	-	HYPH
cord-330553-sukrjl22	171	20	lived	live	VBN
cord-330553-sukrjl22	171	21	,	,	,
cord-330553-sukrjl22	171	22	which	which	WDT
cord-330553-sukrjl22	171	23	may	may	MD
cord-330553-sukrjl22	171	24	lead	lead	VB
cord-330553-sukrjl22	171	25	to	to	IN
cord-330553-sukrjl22	171	26	altered	altered	JJ
cord-330553-sukrjl22	171	27	outcomes	outcome	NNS
cord-330553-sukrjl22	171	28	when	when	WRB
cord-330553-sukrjl22	171	29	comparing	compare	VBG
cord-330553-sukrjl22	171	30	human	human	NN
cord-330553-sukrjl22	171	31	and	and	CC
cord-330553-sukrjl22	171	32	mouse	mouse	NN
cord-330553-sukrjl22	171	33	infections	infection	NNS
cord-330553-sukrjl22	171	34	[	[	-LRB-
cord-330553-sukrjl22	171	35	96	96	CD
cord-330553-sukrjl22	171	36	]	]	-RRB-
cord-330553-sukrjl22	171	37	.	.	.
cord-330553-sukrjl22	172	1	It	-PRON-	PRP
cord-330553-sukrjl22	172	2	is	be	VBZ
cord-330553-sukrjl22	172	3	vital	vital	JJ
cord-330553-sukrjl22	172	4	to	to	IN
cord-330553-sukrjl22	172	5	the	the	DT
cord-330553-sukrjl22	172	6	complete	complete	JJ
cord-330553-sukrjl22	172	7	understanding	understanding	NN
cord-330553-sukrjl22	172	8	of	of	IN
cord-330553-sukrjl22	172	9	the	the	DT
cord-330553-sukrjl22	172	10	role	role	NN
cord-330553-sukrjl22	172	11	of	of	IN
cord-330553-sukrjl22	172	12	microglia	microglia	NNP
cord-330553-sukrjl22	172	13	during	during	IN
cord-330553-sukrjl22	172	14	a	a	DT
cord-330553-sukrjl22	172	15	WNV	WNV	NNP
cord-330553-sukrjl22	172	16	infection	infection	NN
cord-330553-sukrjl22	172	17	to	to	TO
cord-330553-sukrjl22	172	18	use	use	VB
cord-330553-sukrjl22	172	19	mouse	mouse	NN
cord-330553-sukrjl22	172	20	studies	study	NNS
cord-330553-sukrjl22	172	21	as	as	IN
cord-330553-sukrjl22	172	22	a	a	DT
cord-330553-sukrjl22	172	23	compliment	compliment	NN
cord-330553-sukrjl22	172	24	to	to	IN
cord-330553-sukrjl22	172	25	human	human	JJ
cord-330553-sukrjl22	172	26	studies	study	NNS
cord-330553-sukrjl22	172	27	and	and	CC
cord-330553-sukrjl22	172	28	not	not	RB
cord-330553-sukrjl22	172	29	a	a	DT
cord-330553-sukrjl22	172	30	replacement	replacement	NN
cord-330553-sukrjl22	172	31	.	.	.
cord-330553-sukrjl22	173	1	Understanding	understand	VBG
cord-330553-sukrjl22	173	2	exactly	exactly	RB
cord-330553-sukrjl22	173	3	how	how	WRB
cord-330553-sukrjl22	173	4	microglia	microglia	JJ
cord-330553-sukrjl22	173	5	influence	influence	NN
cord-330553-sukrjl22	174	1	the	the	DT
cord-330553-sukrjl22	174	2	progression	progression	NN
cord-330553-sukrjl22	174	3	and	and	CC
cord-330553-sukrjl22	174	4	recovery	recovery	NN
cord-330553-sukrjl22	174	5	of	of	IN
cord-330553-sukrjl22	174	6	WNV	WNV	NNP
cord-330553-sukrjl22	174	7	neuroinvasive	neuroinvasive	JJ
cord-330553-sukrjl22	174	8	infections	infection	NNS
cord-330553-sukrjl22	174	9	will	will	MD
cord-330553-sukrjl22	174	10	allow	allow	VB
cord-330553-sukrjl22	174	11	for	for	IN
cord-330553-sukrjl22	174	12	the	the	DT
cord-330553-sukrjl22	174	13	development	development	NN
cord-330553-sukrjl22	174	14	of	of	IN
cord-330553-sukrjl22	174	15	specific	specific	JJ
cord-330553-sukrjl22	174	16	treatments	treatment	NNS
cord-330553-sukrjl22	174	17	,	,	,
cord-330553-sukrjl22	174	18	which	which	WDT
cord-330553-sukrjl22	174	19	could	could	MD
cord-330553-sukrjl22	174	20	provide	provide	VB
cord-330553-sukrjl22	174	21	the	the	DT
cord-330553-sukrjl22	174	22	optimal	optimal	JJ
cord-330553-sukrjl22	174	23	outcome	outcome	NN
cord-330553-sukrjl22	174	24	to	to	IN
cord-330553-sukrjl22	174	25	patients	patient	NNS
cord-330553-sukrjl22	174	26	recovering	recover	VBG
cord-330553-sukrjl22	174	27	from	from	IN
cord-330553-sukrjl22	174	28	this	this	DT
cord-330553-sukrjl22	174	29	infection	infection	NN
cord-330553-sukrjl22	174	30	.	.	.
cord-330553-sukrjl22	175	1	Author	Author	NNP
cord-330553-sukrjl22	175	2	Contributions	contribution	NNS
cord-330553-sukrjl22	175	3	:	:	:
cord-330553-sukrjl22	175	4	S.S.	S.S.	NNP
cord-330553-sukrjl22	175	5	was	be	VBD
cord-330553-sukrjl22	175	6	the	the	DT
cord-330553-sukrjl22	175	7	primary	primary	JJ
cord-330553-sukrjl22	175	8	author	author	NN
cord-330553-sukrjl22	175	9	of	of	IN
cord-330553-sukrjl22	175	10	this	this	DT
cord-330553-sukrjl22	175	11	review	review	NN
cord-330553-sukrjl22	175	12	with	with	IN
cord-330553-sukrjl22	175	13	contributions	contribution	NNS
cord-330553-sukrjl22	175	14	by	by	IN
cord-330553-sukrjl22	175	15	P.C.	P.C.	NNP
cord-330553-sukrjl22	175	16	P.C.	P.C.	NNP
cord-330553-sukrjl22	175	17	and	and	CC
cord-330553-sukrjl22	175	18	K.L.T.	K.L.T.	NNP
cord-330553-sukrjl22	175	19	were	be	VBD
cord-330553-sukrjl22	175	20	involved	involve	VBN
cord-330553-sukrjl22	175	21	in	in	IN
cord-330553-sukrjl22	175	22	reviewing	review	VBG
cord-330553-sukrjl22	175	23	and	and	CC
cord-330553-sukrjl22	175	24	editing	edit	VBG
cord-330553-sukrjl22	175	25	the	the	DT
cord-330553-sukrjl22	175	26	manuscript	manuscript	NN
cord-330553-sukrjl22	175	27	.	.	.
cord-330553-sukrjl22	176	1	All	all	DT
cord-330553-sukrjl22	176	2	authors	author	NNS
cord-330553-sukrjl22	176	3	have	have	VBP
cord-330553-sukrjl22	176	4	read	read	VBN
cord-330553-sukrjl22	176	5	and	and	CC
cord-330553-sukrjl22	176	6	agreed	agree	VBN
cord-330553-sukrjl22	176	7	to	to	IN
cord-330553-sukrjl22	176	8	the	the	DT
cord-330553-sukrjl22	176	9	published	publish	VBN
cord-330553-sukrjl22	176	10	version	version	NN
cord-330553-sukrjl22	176	11	of	of	IN
cord-330553-sukrjl22	176	12	the	the	DT
cord-330553-sukrjl22	176	13	manuscript	manuscript	NN
cord-330553-sukrjl22	176	14	.	.	.
cord-330553-sukrjl22	177	1	Funding	funding	NN
cord-330553-sukrjl22	177	2	:	:	:
cord-330553-sukrjl22	178	1	This	this	DT
cord-330553-sukrjl22	178	2	research	research	NN
cord-330553-sukrjl22	178	3	was	be	VBD
cord-330553-sukrjl22	178	4	funded	fund	VBN
cord-330553-sukrjl22	178	5	by	by	IN
cord-330553-sukrjl22	178	6	the	the	DT
cord-330553-sukrjl22	178	7	National	National	NNP
cord-330553-sukrjl22	178	8	Institute	Institute	NNP
cord-330553-sukrjl22	178	9	of	of	IN
cord-330553-sukrjl22	178	10	Health	Health	NNP
cord-330553-sukrjl22	178	11	,	,	,
cord-330553-sukrjl22	178	12	grant	grant	NN
cord-330553-sukrjl22	178	13	number	number	NN
cord-330553-sukrjl22	178	14	NS101208	ns101208	IN
cord-330553-sukrjl22	178	15	and	and	CC
cord-330553-sukrjl22	178	16	the	the	DT
cord-330553-sukrjl22	178	17	Department	Department	NNP
cord-330553-sukrjl22	178	18	of	of	IN
cord-330553-sukrjl22	178	19	Veterans	Veterans	NNP
cord-330553-sukrjl22	178	20	Affairs	Affairs	NNPS
cord-330553-sukrjl22	178	21	,	,	,
cord-330553-sukrjl22	178	22	grant	grant	NN
cord-330553-sukrjl22	178	23	number	number	NN
cord-330553-sukrjl22	178	24	BX000963	bx000963	NN
cord-330553-sukrjl22	178	25	.	.	.
cord-330553-sukrjl22	179	1	Nile	Nile	NNP
cord-330553-sukrjl22	179	2	Virus	Virus	NNP
cord-330553-sukrjl22	179	3	:	:	:
cord-330553-sukrjl22	179	4	Review	Review	NNP
cord-330553-sukrjl22	179	5	of	of	IN
cord-330553-sukrjl22	179	6	the	the	DT
cord-330553-sukrjl22	179	7	Literature	Literature	NNP
cord-330553-sukrjl22	179	8	Long	Long	NNP
cord-330553-sukrjl22	179	9	-	-	HYPH
cord-330553-sukrjl22	179	10	Term	term	NN
cord-330553-sukrjl22	179	11	Prognosis	prognosis	NN
cord-330553-sukrjl22	179	12	for	for	IN
cord-330553-sukrjl22	179	13	Clinical	Clinical	NNP
cord-330553-sukrjl22	179	14	West	West	NNP
cord-330553-sukrjl22	179	15	Nile	Nile	NNP
cord-330553-sukrjl22	179	16	Virus	virus	NN
cord-330553-sukrjl22	179	17	Infection	infection	NN
cord-330553-sukrjl22	180	1	The	the	DT
cord-330553-sukrjl22	180	2	Global	Global	NNP
cord-330553-sukrjl22	180	3	Ecology	Ecology	NNP
cord-330553-sukrjl22	180	4	and	and	CC
cord-330553-sukrjl22	180	5	Epidemiology	Epidemiology	NNP
cord-330553-sukrjl22	180	6	of	of	IN
cord-330553-sukrjl22	180	7	West	West	NNP
cord-330553-sukrjl22	180	8	Nile	Nile	NNP
cord-330553-sukrjl22	180	9	Virus	Virus	NNP
cord-330553-sukrjl22	180	10	West	West	NNP
cord-330553-sukrjl22	180	11	Nile	Nile	NNP
cord-330553-sukrjl22	180	12	virus	virus	NN
cord-330553-sukrjl22	180	13	Clinical	clinical	JJ
cord-330553-sukrjl22	180	14	features	feature	NNS
cord-330553-sukrjl22	180	15	of	of	IN
cord-330553-sukrjl22	180	16	West	West	NNP
cord-330553-sukrjl22	180	17	Nile	Nile	NNP
cord-330553-sukrjl22	180	18	virus	virus	NN
cord-330553-sukrjl22	180	19	epidemic	epidemic	NN
cord-330553-sukrjl22	180	20	in	in	IN
cord-330553-sukrjl22	180	21	Dallas	Dallas	NNP
cord-330553-sukrjl22	180	22	West	West	NNP
cord-330553-sukrjl22	180	23	Nile	Nile	NNP
cord-330553-sukrjl22	180	24	Virus	Virus	NNP
cord-330553-sukrjl22	180	25	Infection	infection	NN
cord-330553-sukrjl22	180	26	in	in	IN
cord-330553-sukrjl22	180	27	the	the	DT
cord-330553-sukrjl22	180	28	Central	Central	NNP
cord-330553-sukrjl22	180	29	Nervous	Nervous	NNP
cord-330553-sukrjl22	180	30	System	System	NNP
cord-330553-sukrjl22	180	31	Matrix	Matrix	NNP
cord-330553-sukrjl22	180	32	-	-	HYPH
cord-330553-sukrjl22	180	33	M	M	NNP
cord-330553-sukrjl22	180	34	TM	TM	NNP
cord-330553-sukrjl22	180	35	adjuvanted	adjuvante	VBN
cord-330553-sukrjl22	180	36	envelope	envelope	NN
cord-330553-sukrjl22	180	37	protein	protein	NN
cord-330553-sukrjl22	180	38	vaccine	vaccine	NN
cord-330553-sukrjl22	180	39	protects	protect	VBZ
cord-330553-sukrjl22	180	40	against	against	IN
cord-330553-sukrjl22	180	41	lethal	lethal	JJ
cord-330553-sukrjl22	180	42	lineage	lineage	NN
cord-330553-sukrjl22	180	43	1	1	CD
cord-330553-sukrjl22	180	44	and	and	CC
cord-330553-sukrjl22	180	45	2	2	CD
cord-330553-sukrjl22	180	46	West	West	NNP
cord-330553-sukrjl22	180	47	Nile	Nile	NNP
cord-330553-sukrjl22	180	48	virus	virus	NN
cord-330553-sukrjl22	180	49	infection	infection	NN
cord-330553-sukrjl22	180	50	in	in	IN
cord-330553-sukrjl22	180	51	mice	mouse	NNS
cord-330553-sukrjl22	180	52	Vaccination	vaccination	NN
cord-330553-sukrjl22	180	53	of	of	IN
cord-330553-sukrjl22	180	54	Mice	Mice	NNP
cord-330553-sukrjl22	180	55	Using	use	VBG
cord-330553-sukrjl22	180	56	the	the	DT
cord-330553-sukrjl22	180	57	West	West	NNP
cord-330553-sukrjl22	180	58	Nile	Nile	NNP
cord-330553-sukrjl22	180	59	Virus	Virus	NNP
cord-330553-sukrjl22	180	60	E	E	NNP
cord-330553-sukrjl22	180	61	-	-	HYPH
cord-330553-sukrjl22	180	62	Protein	Protein	NNP
cord-330553-sukrjl22	180	63	in	in	IN
cord-330553-sukrjl22	180	64	a	a	DT
cord-330553-sukrjl22	180	65	DNA	DNA	NNP
cord-330553-sukrjl22	180	66	Prime	Prime	NNP
cord-330553-sukrjl22	180	67	-	-	HYPH
cord-330553-sukrjl22	180	68	Protein	Protein	NNP
cord-330553-sukrjl22	180	69	Boost	Boost	NNP
cord-330553-sukrjl22	180	70	Strategy	Strategy	NNP
cord-330553-sukrjl22	180	71	Stimulates	stimulate	VBZ
cord-330553-sukrjl22	180	72	Cell	cell	NN
cord-330553-sukrjl22	180	73	-	-	HYPH
cord-330553-sukrjl22	180	74	Mediated	mediate	VBN
cord-330553-sukrjl22	180	75	Immunity	Immunity	NNP
cord-330553-sukrjl22	180	76	and	and	CC
cord-330553-sukrjl22	180	77	Protects	protect	VBZ
cord-330553-sukrjl22	180	78	Mice	mouse	NNS
cord-330553-sukrjl22	180	79	against	against	IN
cord-330553-sukrjl22	180	80	a	a	DT
cord-330553-sukrjl22	180	81	Lethal	lethal	JJ
cord-330553-sukrjl22	180	82	Challenge	challenge	NN
cord-330553-sukrjl22	181	1	The	the	DT
cord-330553-sukrjl22	181	2	live	live	JJ
cord-330553-sukrjl22	181	3	attenuated	attenuated	JJ
cord-330553-sukrjl22	181	4	chimeric	chimeric	JJ
cord-330553-sukrjl22	181	5	vaccine	vaccine	NN
cord-330553-sukrjl22	181	6	rWN	rWN	NNP
cord-330553-sukrjl22	181	7	/	/	SYM
cord-330553-sukrjl22	181	8	DEN4∆30	den4∆30	NN
cord-330553-sukrjl22	181	9	is	be	VBZ
cord-330553-sukrjl22	181	10	well	well	RB
cord-330553-sukrjl22	181	11	-	-	HYPH
cord-330553-sukrjl22	181	12	tolerated	tolerate	VBN
cord-330553-sukrjl22	181	13	and	and	CC
cord-330553-sukrjl22	181	14	immunogenic	immunogenic	JJ
cord-330553-sukrjl22	181	15	in	in	IN
cord-330553-sukrjl22	181	16	healthy	healthy	JJ
cord-330553-sukrjl22	181	17	flavivirus	flavivirus	JJ
cord-330553-sukrjl22	181	18	-	-	JJ
cord-330553-sukrjl22	181	19	naïve	naïve	JJ
cord-330553-sukrjl22	181	20	adult	adult	NN
cord-330553-sukrjl22	181	21	volunteers	volunteer	NNS
cord-330553-sukrjl22	182	1	A	a	DT
cord-330553-sukrjl22	182	2	Hydrogen	Hydrogen	NNP
cord-330553-sukrjl22	182	3	Peroxide	peroxide	NN
cord-330553-sukrjl22	182	4	-	-	HYPH
cord-330553-sukrjl22	182	5	Inactivated	inactivate	VBN
cord-330553-sukrjl22	182	6	Virus	Virus	NNP
cord-330553-sukrjl22	182	7	Vaccine	Vaccine	NNP
cord-330553-sukrjl22	182	8	Elicits	elicit	VBZ
cord-330553-sukrjl22	182	9	Humoral	Humoral	NNP
cord-330553-sukrjl22	182	10	and	and	CC
cord-330553-sukrjl22	182	11	Cellular	Cellular	NNP
cord-330553-sukrjl22	182	12	Immunity	Immunity	NNP
cord-330553-sukrjl22	182	13	and	and	CC
cord-330553-sukrjl22	182	14	Protects	protect	VBZ
cord-330553-sukrjl22	182	15	against	against	IN
cord-330553-sukrjl22	182	16	Lethal	Lethal	NNP
cord-330553-sukrjl22	182	17	West	West	NNP
cord-330553-sukrjl22	182	18	Nile	Nile	NNP
cord-330553-sukrjl22	182	19	Virus	Virus	NNP
cord-330553-sukrjl22	182	20	Infection	infection	NN
cord-330553-sukrjl22	182	21	in	in	IN
cord-330553-sukrjl22	182	22	Aged	Aged	NNP
cord-330553-sukrjl22	182	23	Mice	Mice	NNP
cord-330553-sukrjl22	182	24	Phase	Phase	NNP
cord-330553-sukrjl22	182	25	II	II	NNP
cord-330553-sukrjl22	182	26	,	,	,
cord-330553-sukrjl22	182	27	dose	dose	NN
cord-330553-sukrjl22	182	28	ranging	range	VBG
cord-330553-sukrjl22	182	29	study	study	NN
cord-330553-sukrjl22	182	30	of	of	IN
cord-330553-sukrjl22	182	31	the	the	DT
cord-330553-sukrjl22	182	32	safety	safety	NN
cord-330553-sukrjl22	182	33	and	and	CC
cord-330553-sukrjl22	182	34	immunogenicity	immunogenicity	NN
cord-330553-sukrjl22	182	35	of	of	IN
cord-330553-sukrjl22	182	36	single	single	JJ
cord-330553-sukrjl22	182	37	dose	dose	NN
cord-330553-sukrjl22	182	38	West	West	NNP
cord-330553-sukrjl22	182	39	Nile	Nile	NNP
cord-330553-sukrjl22	182	40	vaccine	vaccine	NN
cord-330553-sukrjl22	182	41	in	in	IN
cord-330553-sukrjl22	182	42	healthy	healthy	JJ
cord-330553-sukrjl22	182	43	adults	adult	NNS
cord-330553-sukrjl22	182	44	≥50	≥50	IN
cord-330553-sukrjl22	182	45	years	year	NNS
cord-330553-sukrjl22	182	46	of	of	IN
cord-330553-sukrjl22	182	47	age	age	NN
cord-330553-sukrjl22	182	48	A	a	DT
cord-330553-sukrjl22	182	49	West	West	NNP
cord-330553-sukrjl22	182	50	Nile	Nile	NNP
cord-330553-sukrjl22	182	51	Virus	virus	NN
cord-330553-sukrjl22	182	52	DNA	DNA	NNP
cord-330553-sukrjl22	182	53	Vaccine	Vaccine	NNP
cord-330553-sukrjl22	182	54	Utilizing	utilize	VBG
cord-330553-sukrjl22	182	55	a	a	DT
cord-330553-sukrjl22	182	56	Modified	modify	VBN
cord-330553-sukrjl22	182	57	Promoter	Promoter	NNP
cord-330553-sukrjl22	182	58	Induces	induce	VBZ
cord-330553-sukrjl22	182	59	Neutralizing	neutralize	VBG
cord-330553-sukrjl22	182	60	Antibody	Antibody	NNP
cord-330553-sukrjl22	182	61	in	in	IN
cord-330553-sukrjl22	182	62	Younger	Younger	NNPS
cord-330553-sukrjl22	182	63	and	and	CC
cord-330553-sukrjl22	182	64	Older	old	JJR
cord-330553-sukrjl22	182	65	Healthy	Healthy	NNP
cord-330553-sukrjl22	182	66	Adults	Adults	NNPS
cord-330553-sukrjl22	182	67	in	in	IN
cord-330553-sukrjl22	182	68	a	a	DT
cord-330553-sukrjl22	182	69	Phase	phase	NN
cord-330553-sukrjl22	183	1	I	-PRON-	PRP
cord-330553-sukrjl22	184	1	Clinical	clinical	JJ
cord-330553-sukrjl22	184	2	Trial	trial	NN
cord-330553-sukrjl22	185	1	A	a	DT
cord-330553-sukrjl22	185	2	West	West	NNP
cord-330553-sukrjl22	185	3	Nile	Nile	NNP
cord-330553-sukrjl22	185	4	Virus	virus	NN
cord-330553-sukrjl22	185	5	DNA	DNA	NNP
cord-330553-sukrjl22	185	6	Vaccine	Vaccine	NNP
cord-330553-sukrjl22	185	7	Induces	induce	VBZ
cord-330553-sukrjl22	185	8	Neutralizing	neutralize	VBG
cord-330553-sukrjl22	185	9	Antibody	Antibody	NNP
cord-330553-sukrjl22	185	10	in	in	IN
cord-330553-sukrjl22	185	11	Healthy	Healthy	NNP
cord-330553-sukrjl22	185	12	Adults	Adults	NNPS
cord-330553-sukrjl22	185	13	during	during	IN
cord-330553-sukrjl22	185	14	a	a	DT
cord-330553-sukrjl22	185	15	Phase	phase	NN
cord-330553-sukrjl22	185	16	1	1	CD
cord-330553-sukrjl22	185	17	Clinical	Clinical	NNP
cord-330553-sukrjl22	185	18	Trial	Trial	NNP
cord-330553-sukrjl22	185	19	A	a	DT
cord-330553-sukrjl22	185	20	live	live	JJ
cord-330553-sukrjl22	185	21	,	,	,
cord-330553-sukrjl22	185	22	attenuated	attenuated	JJ
cord-330553-sukrjl22	185	23	recombinant	recombinant	JJ
cord-330553-sukrjl22	185	24	West	West	NNP
cord-330553-sukrjl22	185	25	Nile	Nile	NNP
cord-330553-sukrjl22	185	26	virus	virus	NN
cord-330553-sukrjl22	185	27	vaccine	vaccine	NN
cord-330553-sukrjl22	185	28	Viral	Viral	NNP
cord-330553-sukrjl22	185	29	Pathogen	Pathogen	NNP
cord-330553-sukrjl22	186	1	-Associated	-Associated	NNP
cord-330553-sukrjl22	186	2	Molecular	Molecular	NNP
cord-330553-sukrjl22	186	3	Patterns	Patterns	NNPS
cord-330553-sukrjl22	186	4	Regulate	regulate	VBP
cord-330553-sukrjl22	186	5	Blood	blood	NN
cord-330553-sukrjl22	186	6	-	-	HYPH
cord-330553-sukrjl22	186	7	Brain	Brain	NNP
cord-330553-sukrjl22	186	8	Barrier	Barrier	NNP
cord-330553-sukrjl22	186	9	Integrity	Integrity	NNP
cord-330553-sukrjl22	186	10	via	via	IN
cord-330553-sukrjl22	186	11	Competing	compete	VBG
cord-330553-sukrjl22	186	12	Innate	innate	JJ
cord-330553-sukrjl22	186	13	Cytokine	cytokine	NN
cord-330553-sukrjl22	186	14	Signals	Signals	NNPS
cord-330553-sukrjl22	186	15	Mechanism	Mechanism	NNP
cord-330553-sukrjl22	186	16	of	of	IN
cord-330553-sukrjl22	186	17	West	West	NNP
cord-330553-sukrjl22	186	18	Nile	Nile	NNP
cord-330553-sukrjl22	186	19	Virus	Virus	NNP
cord-330553-sukrjl22	186	20	Neuroinvasion	Neuroinvasion	NNP
cord-330553-sukrjl22	186	21	:	:	:
cord-330553-sukrjl22	187	1	A	a	DT
cord-330553-sukrjl22	187	2	Critical	Critical	NNP
cord-330553-sukrjl22	187	3	Appraisal	Appraisal	NNP
cord-330553-sukrjl22	187	4	Risk	Risk	NNP
cord-330553-sukrjl22	187	5	Factors	Factors	NNP
cord-330553-sukrjl22	187	6	for	for	IN
cord-330553-sukrjl22	187	7	West	West	NNP
cord-330553-sukrjl22	187	8	Nile	Nile	NNP
cord-330553-sukrjl22	187	9	Virus	Virus	NNP
cord-330553-sukrjl22	187	10	Neuroinvasive	Neuroinvasive	NNP
cord-330553-sukrjl22	187	11	Disease	Disease	NNP
cord-330553-sukrjl22	187	12	,	,	,
cord-330553-sukrjl22	187	13	California	California	NNP
cord-330553-sukrjl22	187	14	Single	Single	NNP
cord-330553-sukrjl22	187	15	Nucleotide	Nucleotide	NNP
cord-330553-sukrjl22	187	16	Polymorphisms	Polymorphisms	NNPS
cord-330553-sukrjl22	187	17	in	in	IN
cord-330553-sukrjl22	187	18	Genes	Genes	NNPS
cord-330553-sukrjl22	187	19	for	for	IN
cord-330553-sukrjl22	187	20	2	2	CD
cord-330553-sukrjl22	187	21	-5	-5	CD
cord-330553-sukrjl22	188	1	-Oligoadenylate	-Oligoadenylate	.
cord-330553-sukrjl22	189	1	Synthetase	Synthetase	NNP
cord-330553-sukrjl22	189	2	and	and	CC
cord-330553-sukrjl22	189	3	RNase	RNase	NNP
cord-330553-sukrjl22	189	4	L	l	NN
cord-330553-sukrjl22	189	5	in	in	IN
cord-330553-sukrjl22	189	6	Patients	patient	NNS
cord-330553-sukrjl22	189	7	Hospitalized	hospitalize	VBN
cord-330553-sukrjl22	189	8	with	with	IN
cord-330553-sukrjl22	189	9	West	West	NNP
cord-330553-sukrjl22	189	10	Nile	Nile	NNP
cord-330553-sukrjl22	189	11	Virus	Virus	NNP
cord-330553-sukrjl22	189	12	Infection	Infection	NNP
cord-330553-sukrjl22	189	13	Genetic	genetic	JJ
cord-330553-sukrjl22	189	14	Deficiency	deficiency	NN
cord-330553-sukrjl22	189	15	of	of	IN
cord-330553-sukrjl22	189	16	Chemokine	Chemokine	NNP
cord-330553-sukrjl22	189	17	Receptor	Receptor	NNP
cord-330553-sukrjl22	189	18	CCR5	CCR5	NNP
cord-330553-sukrjl22	189	19	Is	be	VBZ
cord-330553-sukrjl22	189	20	a	a	DT
cord-330553-sukrjl22	189	21	Strong	strong	JJ
cord-330553-sukrjl22	189	22	Risk	Risk	NNP
cord-330553-sukrjl22	189	23	Factor	factor	NN
cord-330553-sukrjl22	189	24	for	for	IN
cord-330553-sukrjl22	189	25	Symptomatic	symptomatic	JJ
cord-330553-sukrjl22	189	26	West	West	NNP
cord-330553-sukrjl22	189	27	Nile	Nile	NNP
cord-330553-sukrjl22	189	28	Virus	Virus	NNP
cord-330553-sukrjl22	189	29	Infection	infection	NN
cord-330553-sukrjl22	189	30	:	:	:
cord-330553-sukrjl22	190	1	A	a	DT
cord-330553-sukrjl22	190	2	Meta	Meta	NNP
cord-330553-sukrjl22	190	3	-	-	HYPH
cord-330553-sukrjl22	190	4	Analysis	Analysis	NNP
cord-330553-sukrjl22	190	5	of	of	IN
cord-330553-sukrjl22	190	6	4	4	CD
cord-330553-sukrjl22	190	7	Cohorts	Cohorts	NNPS
cord-330553-sukrjl22	190	8	in	in	IN
cord-330553-sukrjl22	190	9	the	the	DT
cord-330553-sukrjl22	190	10	US	US	NNP
cord-330553-sukrjl22	190	11	Epidemic	Epidemic	NNP
cord-330553-sukrjl22	190	12	Death	Death	NNP
cord-330553-sukrjl22	190	13	Receptor	Receptor	NNP
cord-330553-sukrjl22	190	14	-	-	HYPH
cord-330553-sukrjl22	190	15	Mediated	mediate	VBN
cord-330553-sukrjl22	190	16	Apoptotic	Apoptotic	NNP
cord-330553-sukrjl22	190	17	Signaling	Signaling	NNP
cord-330553-sukrjl22	190	18	Is	be	VBZ
cord-330553-sukrjl22	190	19	Activated	activate	VBN
cord-330553-sukrjl22	190	20	in	in	IN
cord-330553-sukrjl22	190	21	the	the	DT
cord-330553-sukrjl22	190	22	Brain	Brain	NNP
cord-330553-sukrjl22	190	23	following	follow	VBG
cord-330553-sukrjl22	190	24	Infection	Infection	NNP
cord-330553-sukrjl22	190	25	with	with	IN
cord-330553-sukrjl22	190	26	West	West	NNP
cord-330553-sukrjl22	190	27	Nile	Nile	NNP
cord-330553-sukrjl22	190	28	Virus	Virus	NNP
cord-330553-sukrjl22	190	29	in	in	IN
cord-330553-sukrjl22	190	30	the	the	DT
cord-330553-sukrjl22	190	31	Absence	absence	NN
cord-330553-sukrjl22	190	32	of	of	IN
cord-330553-sukrjl22	190	33	a	a	DT
cord-330553-sukrjl22	190	34	Peripheral	Peripheral	NNP
cord-330553-sukrjl22	190	35	Immune	Immune	NNP
cord-330553-sukrjl22	190	36	Response	response	NN
cord-330553-sukrjl22	190	37	Caspase	Caspase	NNP
cord-330553-sukrjl22	190	38	3-Dependent	3-dependent	CD
cord-330553-sukrjl22	191	1	Cell	cell	NN
cord-330553-sukrjl22	191	2	Death	death	NN
cord-330553-sukrjl22	191	3	of	of	IN
cord-330553-sukrjl22	191	4	Neurons	Neurons	NNP
cord-330553-sukrjl22	191	5	Contributes	contribute	VBZ
cord-330553-sukrjl22	191	6	to	to	IN
cord-330553-sukrjl22	191	7	the	the	DT
cord-330553-sukrjl22	191	8	Pathogenesis	Pathogenesis	NNP
cord-330553-sukrjl22	191	9	of	of	IN
cord-330553-sukrjl22	191	10	West	West	NNP
cord-330553-sukrjl22	191	11	Nile	Nile	NNP
cord-330553-sukrjl22	191	12	Virus	Virus	NNP
cord-330553-sukrjl22	191	13	Encephalitis	encephalitis	NN
cord-330553-sukrjl22	191	14	Differential	differential	JJ
cord-330553-sukrjl22	191	15	responses	response	NNS
cord-330553-sukrjl22	191	16	of	of	IN
cord-330553-sukrjl22	191	17	human	human	JJ
cord-330553-sukrjl22	191	18	brain	brain	NN
cord-330553-sukrjl22	191	19	cells	cell	NNS
cord-330553-sukrjl22	191	20	to	to	IN
cord-330553-sukrjl22	191	21	West	West	NNP
cord-330553-sukrjl22	191	22	Nile	Nile	NNP
cord-330553-sukrjl22	191	23	virus	virus	NN
cord-330553-sukrjl22	191	24	infection	infection	NN
cord-330553-sukrjl22	191	25	Microglia	Microglia	NNP
cord-330553-sukrjl22	191	26	across	across	IN
cord-330553-sukrjl22	191	27	the	the	DT
cord-330553-sukrjl22	191	28	lifespan	lifespan	NN
cord-330553-sukrjl22	191	29	:	:	:
cord-330553-sukrjl22	192	1	From	from	IN
cord-330553-sukrjl22	192	2	origin	origin	NN
cord-330553-sukrjl22	192	3	to	to	TO
cord-330553-sukrjl22	192	4	function	function	VB
cord-330553-sukrjl22	192	5	in	in	IN
cord-330553-sukrjl22	192	6	brain	brain	NN
cord-330553-sukrjl22	192	7	development	development	NN
cord-330553-sukrjl22	192	8	,	,	,
cord-330553-sukrjl22	192	9	plasticity	plasticity	NN
cord-330553-sukrjl22	192	10	and	and	CC
cord-330553-sukrjl22	192	11	cognition	cognition	NN
cord-330553-sukrjl22	192	12	Origin	Origin	NNP
cord-330553-sukrjl22	192	13	and	and	CC
cord-330553-sukrjl22	192	14	Functions	Functions	NNPS
cord-330553-sukrjl22	192	15	of	of	IN
cord-330553-sukrjl22	192	16	Tissue	tissue	NN
cord-330553-sukrjl22	192	17	Macrophages	Macrophages	NNP
cord-330553-sukrjl22	192	18	Origin	Origin	NNP
cord-330553-sukrjl22	192	19	and	and	CC
cord-330553-sukrjl22	192	20	differentiation	differentiation	NN
cord-330553-sukrjl22	192	21	of	of	IN
cord-330553-sukrjl22	192	22	microglia	microglia	JJ
cord-330553-sukrjl22	192	23	Microglia	Microglia	NNP
cord-330553-sukrjl22	192	24	Development	Development	NNP
cord-330553-sukrjl22	192	25	and	and	CC
cord-330553-sukrjl22	192	26	function	function	VB
cord-330553-sukrjl22	192	27	The	the	DT
cord-330553-sukrjl22	192	28	Role	role	NN
cord-330553-sukrjl22	192	29	of	of	IN
cord-330553-sukrjl22	192	30	Microglia	Microglia	NNP
cord-330553-sukrjl22	192	31	in	in	IN
cord-330553-sukrjl22	192	32	the	the	DT
cord-330553-sukrjl22	192	33	Healthy	Healthy	NNP
cord-330553-sukrjl22	192	34	Brain	Brain	NNP
cord-330553-sukrjl22	193	1	The	the	DT
cord-330553-sukrjl22	193	2	Role	role	NN
cord-330553-sukrjl22	193	3	of	of	IN
cord-330553-sukrjl22	193	4	Microglia	Microglia	NNP
cord-330553-sukrjl22	193	5	in	in	IN
cord-330553-sukrjl22	193	6	Central	Central	NNP
cord-330553-sukrjl22	193	7	Nervous	Nervous	NNP
cord-330553-sukrjl22	193	8	System	System	NNP
cord-330553-sukrjl22	193	9	Immunity	Immunity	NNP
cord-330553-sukrjl22	193	10	and	and	CC
cord-330553-sukrjl22	193	11	Glioma	Glioma	NNP
cord-330553-sukrjl22	193	12	Immunology	Immunology	NNP
cord-330553-sukrjl22	193	13	Microglial	Microglial	NNP
cord-330553-sukrjl22	193	14	Physiology	Physiology	NNP
cord-330553-sukrjl22	193	15	and	and	CC
cord-330553-sukrjl22	193	16	Pathophysiology	pathophysiology	NN
cord-330553-sukrjl22	193	17	:	:	:
cord-330553-sukrjl22	194	1	Insights	insight	NNS
cord-330553-sukrjl22	194	2	from	from	IN
cord-330553-sukrjl22	194	3	Genome	genome	NN
cord-330553-sukrjl22	194	4	-	-	HYPH
cord-330553-sukrjl22	194	5	wide	wide	JJ
cord-330553-sukrjl22	194	6	Transcriptional	Transcriptional	NNP
cord-330553-sukrjl22	194	7	Profiling	Profiling	NNP
cord-330553-sukrjl22	194	8	Features	Features	NNPS
cord-330553-sukrjl22	194	9	of	of	IN
cord-330553-sukrjl22	194	10	Microglia	Microglia	NNP
cord-330553-sukrjl22	194	11	and	and	CC
cord-330553-sukrjl22	194	12	Neuroinflammation	Neuroinflammation	NNP
cord-330553-sukrjl22	194	13	Relevant	relevant	JJ
cord-330553-sukrjl22	194	14	to	to	IN
cord-330553-sukrjl22	194	15	Environmental	Environmental	NNP
cord-330553-sukrjl22	194	16	Exposure	Exposure	NNP
cord-330553-sukrjl22	194	17	and	and	CC
cord-330553-sukrjl22	195	1	Neurotoxicity	Neurotoxicity	NNP
cord-330553-sukrjl22	195	2	A	a	DT
cord-330553-sukrjl22	195	3	polarizing	polarizing	JJ
cord-330553-sukrjl22	195	4	question	question	NN
cord-330553-sukrjl22	195	5	:	:	:
cord-330553-sukrjl22	195	6	Do	Do	NNP
cord-330553-sukrjl22	195	7	M1	M1	NNP
cord-330553-sukrjl22	195	8	and	and	CC
cord-330553-sukrjl22	195	9	M2	M2	NNP
cord-330553-sukrjl22	195	10	microglia	microglia	NNS
cord-330553-sukrjl22	195	11	exist	exist	VBP
cord-330553-sukrjl22	195	12	?	?	.
cord-330553-sukrjl22	196	1	Alternatively	alternatively	RB
cord-330553-sukrjl22	196	2	activated	activate	VBN
cord-330553-sukrjl22	196	3	microglia	microglia	NNS
cord-330553-sukrjl22	196	4	and	and	CC
cord-330553-sukrjl22	196	5	macrophages	macrophage	NNS
cord-330553-sukrjl22	196	6	in	in	IN
cord-330553-sukrjl22	196	7	the	the	DT
cord-330553-sukrjl22	196	8	central	central	JJ
cord-330553-sukrjl22	196	9	nervous	nervous	JJ
cord-330553-sukrjl22	196	10	system	system	NN
cord-330553-sukrjl22	196	11	Review	Review	NNP
cord-330553-sukrjl22	196	12	:	:	:
cord-330553-sukrjl22	196	13	Activation	activation	NN
cord-330553-sukrjl22	196	14	patterns	pattern	NNS
cord-330553-sukrjl22	196	15	of	of	IN
cord-330553-sukrjl22	196	16	microglia	microglia	NNS
cord-330553-sukrjl22	196	17	and	and	CC
cord-330553-sukrjl22	196	18	their	-PRON-	PRP$
cord-330553-sukrjl22	196	19	identification	identification	NN
cord-330553-sukrjl22	196	20	in	in	IN
cord-330553-sukrjl22	196	21	the	the	DT
cord-330553-sukrjl22	196	22	human	human	JJ
cord-330553-sukrjl22	196	23	brain	brain	NN
cord-330553-sukrjl22	196	24	Sequential	Sequential	NNP
cord-330553-sukrjl22	196	25	Activation	Activation	NNP
cord-330553-sukrjl22	196	26	of	of	IN
cord-330553-sukrjl22	196	27	Microglia	Microglia	NNP
cord-330553-sukrjl22	196	28	and	and	CC
cord-330553-sukrjl22	196	29	Astrocyte	Astrocyte	NNP
cord-330553-sukrjl22	196	30	Cytokine	Cytokine	NNP
cord-330553-sukrjl22	196	31	Expression	expression	NN
cord-330553-sukrjl22	197	1	Precedes	precedes	NN
cord-330553-sukrjl22	198	1	Increased	increase	VBN
cord-330553-sukrjl22	198	2	Iba-1	Iba-1	NNP
cord-330553-sukrjl22	198	3	or	or	CC
cord-330553-sukrjl22	198	4	GFAP	GFAP	NNP
cord-330553-sukrjl22	198	5	Immunoreactivity	Immunoreactivity	NNP
cord-330553-sukrjl22	198	6	following	follow	VBG
cord-330553-sukrjl22	198	7	Systemic	Systemic	NNP
cord-330553-sukrjl22	198	8	Immune	immune	JJ
cord-330553-sukrjl22	198	9	Challenge	challenge	NN
cord-330553-sukrjl22	198	10	Immune	immune	JJ
cord-330553-sukrjl22	198	11	phenotypes	phenotype	NNS
cord-330553-sukrjl22	198	12	of	of	IN
cord-330553-sukrjl22	198	13	microglia	microglia	NNS
cord-330553-sukrjl22	198	14	in	in	IN
cord-330553-sukrjl22	198	15	human	human	JJ
cord-330553-sukrjl22	198	16	neurodegenerative	neurodegenerative	JJ
cord-330553-sukrjl22	198	17	disease	disease	NN
cord-330553-sukrjl22	198	18	:	:	:
cord-330553-sukrjl22	198	19	Challenges	challenge	NNS
cord-330553-sukrjl22	198	20	to	to	IN
cord-330553-sukrjl22	198	21	detecting	detect	VBG
cord-330553-sukrjl22	198	22	microglial	microglial	JJ
cord-330553-sukrjl22	198	23	polarization	polarization	NN
cord-330553-sukrjl22	198	24	in	in	IN
cord-330553-sukrjl22	198	25	human	human	JJ
cord-330553-sukrjl22	198	26	brains	brain	NNS
cord-330553-sukrjl22	199	1	Long	Long	NNP
cord-330553-sukrjl22	199	2	-	-	HYPH
cord-330553-sukrjl22	199	3	Distance	distance	NN
cord-330553-sukrjl22	199	4	Interferon	Interferon	NNP
cord-330553-sukrjl22	200	1	Signaling	signal	VBG
cord-330553-sukrjl22	200	2	within	within	IN
cord-330553-sukrjl22	200	3	the	the	DT
cord-330553-sukrjl22	200	4	Brain	Brain	NNP
cord-330553-sukrjl22	200	5	Blocks	Blocks	NNP
cord-330553-sukrjl22	200	6	Virus	Virus	NNP
cord-330553-sukrjl22	200	7	Spread	Spread	VBD
cord-330553-sukrjl22	200	8	Neurophagy	Neurophagy	NNP
cord-330553-sukrjl22	200	9	,	,	,
cord-330553-sukrjl22	200	10	the	the	DT
cord-330553-sukrjl22	200	11	phagocytosis	phagocytosis	NN
cord-330553-sukrjl22	200	12	of	of	IN
cord-330553-sukrjl22	200	13	live	live	JJ
cord-330553-sukrjl22	200	14	neurons	neuron	NNS
cord-330553-sukrjl22	200	15	and	and	CC
cord-330553-sukrjl22	200	16	synapses	synapsis	NNS
cord-330553-sukrjl22	200	17	by	by	IN
cord-330553-sukrjl22	200	18	glia	glia	NNP
cord-330553-sukrjl22	200	19	,	,	,
cord-330553-sukrjl22	200	20	contributes	contribute	VBZ
cord-330553-sukrjl22	200	21	to	to	IN
cord-330553-sukrjl22	200	22	brain	brain	NN
cord-330553-sukrjl22	200	23	development	development	NN
cord-330553-sukrjl22	200	24	and	and	CC
cord-330553-sukrjl22	200	25	disease	disease	NN
cord-330553-sukrjl22	200	26	Microglia	Microglia	NNP
cord-330553-sukrjl22	200	27	-	-	HYPH
cord-330553-sukrjl22	200	28	Mediated	mediate	VBN
cord-330553-sukrjl22	200	29	Inflammation	Inflammation	NNP
cord-330553-sukrjl22	200	30	and	and	CC
cord-330553-sukrjl22	200	31	Neurodegenerative	Neurodegenerative	NNP
cord-330553-sukrjl22	200	32	Disease	Disease	NNP
cord-330553-sukrjl22	200	33	Microglial	Microglial	NNP
cord-330553-sukrjl22	200	34	M1	M1	NNP
cord-330553-sukrjl22	200	35	/	/	SYM
cord-330553-sukrjl22	200	36	M2	m2	JJ
cord-330553-sukrjl22	200	37	polarization	polarization	NN
cord-330553-sukrjl22	200	38	and	and	CC
cord-330553-sukrjl22	200	39	metabolic	metabolic	JJ
cord-330553-sukrjl22	200	40	states	state	NNS
cord-330553-sukrjl22	200	41	Activation	Activation	NNP
cord-330553-sukrjl22	200	42	of	of	IN
cord-330553-sukrjl22	200	43	Intrinsic	Intrinsic	NNP
cord-330553-sukrjl22	200	44	Immune	Immune	NNP
cord-330553-sukrjl22	200	45	Responses	Responses	NNPS
cord-330553-sukrjl22	200	46	and	and	CC
cord-330553-sukrjl22	200	47	Microglial	Microglial	NNP
cord-330553-sukrjl22	200	48	Phagocytosis	Phagocytosis	NNP
cord-330553-sukrjl22	200	49	in	in	IN
cord-330553-sukrjl22	200	50	an	an	DT
cord-330553-sukrjl22	200	51	Ex	Ex	NNP
cord-330553-sukrjl22	200	52	Vivo	Vivo	NNP
cord-330553-sukrjl22	200	53	Spinal	Spinal	NNP
cord-330553-sukrjl22	200	54	Cord	cord	NN
cord-330553-sukrjl22	200	55	Slice	slice	NN
cord-330553-sukrjl22	200	56	Culture	Culture	NNP
cord-330553-sukrjl22	200	57	Model	Model	NNP
cord-330553-sukrjl22	200	58	of	of	IN
cord-330553-sukrjl22	200	59	West	West	NNP
cord-330553-sukrjl22	200	60	Nile	Nile	NNP
cord-330553-sukrjl22	200	61	Virus	Virus	NNP
cord-330553-sukrjl22	200	62	Infection	infection	NN
cord-330553-sukrjl22	200	63	Minocycline	Minocycline	NNP
cord-330553-sukrjl22	201	1	Has	have	VBZ
cord-330553-sukrjl22	201	2	Anti	anti	JJ
cord-330553-sukrjl22	201	3	-	-	JJ
cord-330553-sukrjl22	201	4	inflammatory	inflammatory	JJ
cord-330553-sukrjl22	201	5	Effects	effect	NNS
cord-330553-sukrjl22	201	6	and	and	CC
cord-330553-sukrjl22	201	7	Reduces	reduce	VBZ
cord-330553-sukrjl22	201	8	Cytotoxicity	Cytotoxicity	NNP
cord-330553-sukrjl22	201	9	in	in	IN
cord-330553-sukrjl22	201	10	an	an	DT
cord-330553-sukrjl22	201	11	Ex	Ex	NNP
cord-330553-sukrjl22	201	12	Vivo	Vivo	NNP
cord-330553-sukrjl22	201	13	Spinal	Spinal	NNP
cord-330553-sukrjl22	201	14	Cord	cord	NN
cord-330553-sukrjl22	201	15	Slice	slice	NN
cord-330553-sukrjl22	201	16	Culture	Culture	NNP
cord-330553-sukrjl22	201	17	Model	Model	NNP
cord-330553-sukrjl22	201	18	of	of	IN
cord-330553-sukrjl22	201	19	West	West	NNP
cord-330553-sukrjl22	201	20	Nile	Nile	NNP
cord-330553-sukrjl22	201	21	Virus	Virus	NNP
cord-330553-sukrjl22	201	22	Infection	infection	NN
cord-330553-sukrjl22	201	23	Impaired	impair	VBD
cord-330553-sukrjl22	201	24	Autophagy	Autophagy	NNP
cord-330553-sukrjl22	201	25	Flux	Flux	NNP
cord-330553-sukrjl22	201	26	is	be	VBZ
cord-330553-sukrjl22	201	27	Associated	associate	VBN
cord-330553-sukrjl22	201	28	with	with	IN
cord-330553-sukrjl22	201	29	Proinflammatory	Proinflammatory	NNP
cord-330553-sukrjl22	201	30	Microglia	Microglia	NNP
cord-330553-sukrjl22	201	31	Activation	Activation	NNP
cord-330553-sukrjl22	201	32	Following	follow	VBG
cord-330553-sukrjl22	201	33	Japanese	japanese	JJ
cord-330553-sukrjl22	201	34	Encephalitis	Encephalitis	NNP
cord-330553-sukrjl22	201	35	Virus	virus	NN
cord-330553-sukrjl22	201	36	Infection	Infection	NNP
cord-330553-sukrjl22	201	37	Recent	Recent	NNP
cord-330553-sukrjl22	201	38	advances	advance	NNS
cord-330553-sukrjl22	201	39	in	in	IN
cord-330553-sukrjl22	201	40	understanding	understanding	NN
cord-330553-sukrjl22	202	1	Japanese	japanese	JJ
cord-330553-sukrjl22	202	2	encephalitis	encephalitis	RB
cord-330553-sukrjl22	202	3	Dengue	dengue	NN
cord-330553-sukrjl22	202	4	virus	virus	NN
cord-330553-sukrjl22	202	5	infection	infection	NN
cord-330553-sukrjl22	202	6	increases	increase	VBZ
cord-330553-sukrjl22	202	7	microglial	microglial	JJ
cord-330553-sukrjl22	202	8	cell	cell	NN
cord-330553-sukrjl22	202	9	migration	migration	NN
cord-330553-sukrjl22	202	10	Role	role	NN
cord-330553-sukrjl22	202	11	of	of	IN
cord-330553-sukrjl22	202	12	microglia	microglia	NNS
cord-330553-sukrjl22	202	13	in	in	IN
cord-330553-sukrjl22	202	14	the	the	DT
cord-330553-sukrjl22	202	15	dissemination	dissemination	NN
cord-330553-sukrjl22	202	16	of	of	IN
cord-330553-sukrjl22	202	17	Zika	Zika	NNP
cord-330553-sukrjl22	202	18	virus	virus	NN
cord-330553-sukrjl22	202	19	from	from	IN
cord-330553-sukrjl22	202	20	mother	mother	NN
cord-330553-sukrjl22	202	21	to	to	IN
cord-330553-sukrjl22	202	22	fetal	fetal	JJ
cord-330553-sukrjl22	202	23	brain	brain	NN
cord-330553-sukrjl22	203	1	A	a	DT
cord-330553-sukrjl22	203	2	Tick	tick	VB
cord-330553-sukrjl22	203	3	-	-	HYPH
cord-330553-sukrjl22	203	4	Borne	Borne	NNP
cord-330553-sukrjl22	203	5	Encephalitis	Encephalitis	NNP
cord-330553-sukrjl22	203	6	Model	Model	NNP
cord-330553-sukrjl22	203	7	in	in	IN
cord-330553-sukrjl22	203	8	Infant	Infant	NNP
cord-330553-sukrjl22	203	9	Rats	rat	NNS
cord-330553-sukrjl22	204	1	Infected	infect	VBN
cord-330553-sukrjl22	204	2	With	with	IN
cord-330553-sukrjl22	204	3	Langat	Langat	NNP
cord-330553-sukrjl22	204	4	Virus	Virus	NNP
cord-330553-sukrjl22	204	5	Activation	Activation	NNP
cord-330553-sukrjl22	204	6	of	of	IN
cord-330553-sukrjl22	204	7	Innate	Innate	NNP
cord-330553-sukrjl22	204	8	Immune	Immune	NNP
cord-330553-sukrjl22	204	9	Responses	Responses	NNPS
cord-330553-sukrjl22	204	10	in	in	IN
cord-330553-sukrjl22	204	11	the	the	DT
cord-330553-sukrjl22	204	12	Central	Central	NNP
cord-330553-sukrjl22	204	13	Nervous	Nervous	NNP
cord-330553-sukrjl22	204	14	System	System	NNP
cord-330553-sukrjl22	204	15	during	during	IN
cord-330553-sukrjl22	204	16	Reovirus	Reovirus	NNP
cord-330553-sukrjl22	204	17	Myelitis	Myelitis	NNP
cord-330553-sukrjl22	204	18	Microglia	Microglia	NNP
cord-330553-sukrjl22	204	19	are	be	VBP
cord-330553-sukrjl22	204	20	required	require	VBN
cord-330553-sukrjl22	204	21	for	for	IN
cord-330553-sukrjl22	204	22	protection	protection	NN
cord-330553-sukrjl22	204	23	against	against	IN
cord-330553-sukrjl22	204	24	lethal	lethal	JJ
cord-330553-sukrjl22	204	25	coronavirus	coronavirus	NN
cord-330553-sukrjl22	204	26	encephalitis	encephalitis	RB
cord-330553-sukrjl22	204	27	in	in	IN
cord-330553-sukrjl22	204	28	mice	mouse	NNS
cord-330553-sukrjl22	205	1	Microglia	Microglia	NNP
cord-330553-sukrjl22	205	2	influence	influence	NN
cord-330553-sukrjl22	205	3	host	host	NN
cord-330553-sukrjl22	205	4	defense	defense	NN
cord-330553-sukrjl22	205	5	,	,	,
cord-330553-sukrjl22	205	6	disease	disease	NN
cord-330553-sukrjl22	205	7	,	,	,
cord-330553-sukrjl22	205	8	and	and	CC
cord-330553-sukrjl22	205	9	repair	repair	VB
cord-330553-sukrjl22	205	10	following	follow	VBG
cord-330553-sukrjl22	205	11	murine	murine	JJ
cord-330553-sukrjl22	205	12	coronavirus	coronavirus	NN
cord-330553-sukrjl22	205	13	infection	infection	NN
cord-330553-sukrjl22	205	14	of	of	IN
cord-330553-sukrjl22	205	15	the	the	DT
cord-330553-sukrjl22	205	16	central	central	JJ
cord-330553-sukrjl22	205	17	nervous	nervous	JJ
cord-330553-sukrjl22	205	18	system	system	NN
cord-330553-sukrjl22	205	19	Spinal	spinal	JJ
cord-330553-sukrjl22	205	20	cord	cord	NN
cord-330553-sukrjl22	205	21	neuropathology	neuropathology	NN
cord-330553-sukrjl22	205	22	in	in	IN
cord-330553-sukrjl22	205	23	human	human	JJ
cord-330553-sukrjl22	205	24	West	West	NNP
cord-330553-sukrjl22	205	25	Nile	Nile	NNP
cord-330553-sukrjl22	205	26	virus	virus	NN
cord-330553-sukrjl22	205	27	infection	infection	NN
cord-330553-sukrjl22	205	28	Virology	Virology	NNP
cord-330553-sukrjl22	205	29	,	,	,
cord-330553-sukrjl22	205	30	Pathology	Pathology	NNP
cord-330553-sukrjl22	205	31	,	,	,
cord-330553-sukrjl22	205	32	and	and	CC
cord-330553-sukrjl22	205	33	Clinical	Clinical	NNP
cord-330553-sukrjl22	205	34	Manifestations	Manifestations	NNPS
cord-330553-sukrjl22	205	35	of	of	IN
cord-330553-sukrjl22	205	36	West	West	NNP
cord-330553-sukrjl22	205	37	Nile	Nile	NNP
cord-330553-sukrjl22	205	38	Virus	Virus	NNP
cord-330553-sukrjl22	205	39	Disease	Disease	NNP
cord-330553-sukrjl22	206	1	The	the	DT
cord-330553-sukrjl22	206	2	immune	immune	JJ
cord-330553-sukrjl22	206	3	adaptor	adaptor	NN
cord-330553-sukrjl22	206	4	molecule	molecule	NN
cord-330553-sukrjl22	206	5	SARM	SARM	NNP
cord-330553-sukrjl22	206	6	modulates	modulate	VBZ
cord-330553-sukrjl22	206	7	tumor	tumor	NN
cord-330553-sukrjl22	206	8	necrosis	necrosis	NN
cord-330553-sukrjl22	206	9	factor	factor	NN
cord-330553-sukrjl22	206	10	alpha	alpha	NN
cord-330553-sukrjl22	206	11	production	production	NN
cord-330553-sukrjl22	206	12	and	and	CC
cord-330553-sukrjl22	206	13	microglia	microglia	NN
cord-330553-sukrjl22	206	14	activation	activation	NN
cord-330553-sukrjl22	206	15	in	in	IN
cord-330553-sukrjl22	206	16	the	the	DT
cord-330553-sukrjl22	206	17	brainstem	brainstem	NN
cord-330553-sukrjl22	206	18	and	and	CC
cord-330553-sukrjl22	206	19	restricts	restrict	VBZ
cord-330553-sukrjl22	206	20	West	West	NNP
cord-330553-sukrjl22	206	21	Nile	Nile	NNP
cord-330553-sukrjl22	206	22	Virus	Virus	NNP
cord-330553-sukrjl22	206	23	pathogenesis	pathogenesis	NN
cord-330553-sukrjl22	206	24	TLR	TLR	NNP
cord-330553-sukrjl22	206	25	signaling	signal	VBG
cord-330553-sukrjl22	206	26	controls	control	NNS
cord-330553-sukrjl22	206	27	lethal	lethal	JJ
cord-330553-sukrjl22	206	28	encephalitis	encephalitis	RB
cord-330553-sukrjl22	206	29	in	in	IN
cord-330553-sukrjl22	206	30	WNV	WNV	NNP
cord-330553-sukrjl22	206	31	-	-	HYPH
cord-330553-sukrjl22	206	32	infected	infect	VBN
cord-330553-sukrjl22	206	33	brain	brain	NN
cord-330553-sukrjl22	207	1	West	West	NNP
cord-330553-sukrjl22	207	2	Nile	Nile	NNP
cord-330553-sukrjl22	207	3	Virus	Virus	NNP
cord-330553-sukrjl22	207	4	spread	spread	VBD
cord-330553-sukrjl22	207	5	and	and	CC
cord-330553-sukrjl22	207	6	differential	differential	JJ
cord-330553-sukrjl22	207	7	chemokine	chemokine	NN
cord-330553-sukrjl22	207	8	response	response	NN
cord-330553-sukrjl22	207	9	in	in	IN
cord-330553-sukrjl22	207	10	the	the	DT
cord-330553-sukrjl22	207	11	central	central	JJ
cord-330553-sukrjl22	207	12	nervous	nervous	JJ
cord-330553-sukrjl22	207	13	system	system	NN
cord-330553-sukrjl22	207	14	of	of	IN
cord-330553-sukrjl22	207	15	mice	mouse	NNS
cord-330553-sukrjl22	207	16	:	:	:
cord-330553-sukrjl22	208	1	Role	role	NN
cord-330553-sukrjl22	208	2	in	in	IN
cord-330553-sukrjl22	208	3	pathogenic	pathogenic	JJ
cord-330553-sukrjl22	208	4	mechanisms	mechanism	NNS
cord-330553-sukrjl22	208	5	of	of	IN
cord-330553-sukrjl22	208	6	encephalitis	encephalitis	JJ
cord-330553-sukrjl22	208	7	Microglia	Microglia	NNP
cord-330553-sukrjl22	208	8	-	-	HYPH
cord-330553-sukrjl22	208	9	specific	specific	JJ
cord-330553-sukrjl22	208	10	localisation	localisation	NN
cord-330553-sukrjl22	208	11	of	of	IN
cord-330553-sukrjl22	208	12	a	a	DT
cord-330553-sukrjl22	208	13	novel	novel	JJ
cord-330553-sukrjl22	208	14	calcium	calcium	NN
cord-330553-sukrjl22	208	15	binding	bind	VBG
cord-330553-sukrjl22	208	16	protein	protein	NN
cord-330553-sukrjl22	208	17	,	,	.
cord-330553-sukrjl22	209	1	Iba1	Iba1	NNP
cord-330553-sukrjl22	209	2	Intercellular	Intercellular	NNP
cord-330553-sukrjl22	209	3	Communication	Communication	NNP
cord-330553-sukrjl22	209	4	Is	be	VBZ
cord-330553-sukrjl22	209	5	Key	key	JJ
cord-330553-sukrjl22	209	6	for	for	IN
cord-330553-sukrjl22	209	7	Protective	Protective	NNP
cord-330553-sukrjl22	209	8	IFNα/	IFNα/	NNP
cord-330553-sukrjl22	210	1	β	β	NN
cord-330553-sukrjl22	211	1	Signaling	signal	VBG
cord-330553-sukrjl22	211	2	during	during	IN
cord-330553-sukrjl22	211	3	Viral	Viral	NNP
cord-330553-sukrjl22	211	4	Central	Central	NNP
cord-330553-sukrjl22	211	5	Nervous	Nervous	NNP
cord-330553-sukrjl22	211	6	System	System	NNP
cord-330553-sukrjl22	211	7	Infection	Infection	NNP
cord-330553-sukrjl22	211	8	Interleukin	Interleukin	NNP
cord-330553-sukrjl22	211	9	17	17	CD
cord-330553-sukrjl22	211	10	Receptor	Receptor	NNP
cord-330553-sukrjl22	211	11	A	A	NNP
cord-330553-sukrjl22	211	12	,	,	,
cord-330553-sukrjl22	211	13	and	and	CC
cord-330553-sukrjl22	211	14	Glutamate	glutamate	NN
cord-330553-sukrjl22	211	15	Signaling	Signaling	NNP
cord-330553-sukrjl22	211	16	as	as	RB
cord-330553-sukrjl22	211	17	Well	well	RB
cord-330553-sukrjl22	211	18	as	as	IN
cord-330553-sukrjl22	211	19	Flavivirus	Flavivirus	NNP
cord-330553-sukrjl22	211	20	-	-	HYPH
cord-330553-sukrjl22	211	21	Specific	specific	JJ
cord-330553-sukrjl22	211	22	Upregulation	Upregulation	NNP
cord-330553-sukrjl22	211	23	of	of	IN
cord-330553-sukrjl22	211	24	tRNA	trna	NN
cord-330553-sukrjl22	211	25	Synthetases	Synthetases	NNP
cord-330553-sukrjl22	211	26	Microglia	Microglia	NNP
cord-330553-sukrjl22	211	27	in	in	IN
cord-330553-sukrjl22	211	28	central	central	JJ
cord-330553-sukrjl22	211	29	nervous	nervous	JJ
cord-330553-sukrjl22	211	30	system	system	NN
cord-330553-sukrjl22	211	31	repair	repair	NN
cord-330553-sukrjl22	211	32	after	after	IN
cord-330553-sukrjl22	211	33	injury	injury	NN
cord-330553-sukrjl22	211	34	Pharmacologic	Pharmacologic	NNP
cord-330553-sukrjl22	211	35	Depletion	Depletion	NNP
cord-330553-sukrjl22	211	36	of	of	IN
cord-330553-sukrjl22	211	37	Microglia	Microglia	NNP
cord-330553-sukrjl22	211	38	Increases	increase	VBZ
cord-330553-sukrjl22	211	39	Viral	Viral	NNP
cord-330553-sukrjl22	211	40	Load	Load	NNP
cord-330553-sukrjl22	211	41	in	in	IN
cord-330553-sukrjl22	211	42	the	the	DT
cord-330553-sukrjl22	211	43	Brain	Brain	NNP
cord-330553-sukrjl22	211	44	and	and	CC
cord-330553-sukrjl22	211	45	Enhances	enhance	VBZ
cord-330553-sukrjl22	211	46	Mortality	mortality	NN
cord-330553-sukrjl22	211	47	in	in	IN
cord-330553-sukrjl22	211	48	Murine	Murine	NNP
cord-330553-sukrjl22	211	49	Models	Models	NNPS
cord-330553-sukrjl22	211	50	of	of	IN
cord-330553-sukrjl22	211	51	Flavivirus	Flavivirus	NNP
cord-330553-sukrjl22	211	52	-	-	HYPH
cord-330553-sukrjl22	211	53	Induced	Induced	NNP
cord-330553-sukrjl22	211	54	Encephalitis	Encephalitis	NNP
cord-330553-sukrjl22	211	55	Toll	toll	NN
cord-330553-sukrjl22	211	56	-	-	HYPH
cord-330553-sukrjl22	211	57	like	like	JJ
cord-330553-sukrjl22	211	58	receptors	receptor	NNS
cord-330553-sukrjl22	211	59	and	and	CC
cord-330553-sukrjl22	211	60	innate	innate	JJ
cord-330553-sukrjl22	211	61	immunity	immunity	NN
cord-330553-sukrjl22	211	62	Toll	toll	NN
cord-330553-sukrjl22	211	63	-	-	HYPH
cord-330553-sukrjl22	211	64	like	like	JJ
cord-330553-sukrjl22	211	65	receptors	receptor	NNS
cord-330553-sukrjl22	211	66	in	in	IN
cord-330553-sukrjl22	211	67	health	health	NN
cord-330553-sukrjl22	211	68	and	and	CC
cord-330553-sukrjl22	211	69	disease	disease	NN
cord-330553-sukrjl22	211	70	in	in	IN
cord-330553-sukrjl22	211	71	the	the	DT
cord-330553-sukrjl22	211	72	brain	brain	NN
cord-330553-sukrjl22	211	73	:	:	:
cord-330553-sukrjl22	211	74	Mechanisms	mechanism	NNS
cord-330553-sukrjl22	211	75	and	and	CC
cord-330553-sukrjl22	211	76	therapeutic	therapeutic	JJ
cord-330553-sukrjl22	211	77	potential	potential	NN
cord-330553-sukrjl22	212	1	Microglia	Microglia	NNP
cord-330553-sukrjl22	212	2	Recognize	recognize	VBP
cord-330553-sukrjl22	212	3	Double	Double	NNP
cord-330553-sukrjl22	212	4	-	-	HYPH
cord-330553-sukrjl22	212	5	Stranded	Stranded	NNP
cord-330553-sukrjl22	212	6	RNA	RNA	NNP
cord-330553-sukrjl22	212	7	via	via	IN
cord-330553-sukrjl22	212	8	TLR3	TLR3	NNP
cord-330553-sukrjl22	213	1	Toll	toll	NN
cord-330553-sukrjl22	213	2	-	-	HYPH
cord-330553-sukrjl22	213	3	Like	like	JJ
cord-330553-sukrjl22	213	4	Receptor	Receptor	NNP
cord-330553-sukrjl22	213	5	3	3	CD
cord-330553-sukrjl22	213	6	Has	have	VBZ
cord-330553-sukrjl22	213	7	a	a	DT
cord-330553-sukrjl22	213	8	Protective	Protective	NNP
cord-330553-sukrjl22	213	9	Role	role	NN
cord-330553-sukrjl22	213	10	against	against	IN
cord-330553-sukrjl22	213	11	West	West	NNP
cord-330553-sukrjl22	213	12	Nile	Nile	NNP
cord-330553-sukrjl22	213	13	Virus	Virus	NNP
cord-330553-sukrjl22	213	14	Infection	infection	NN
cord-330553-sukrjl22	213	15	Role	role	NN
cord-330553-sukrjl22	213	16	of	of	IN
cord-330553-sukrjl22	213	17	NS1	ns1	NN
cord-330553-sukrjl22	213	18	and	and	CC
cord-330553-sukrjl22	213	19	TLR3	TLR3	NNP
cord-330553-sukrjl22	213	20	in	in	IN
cord-330553-sukrjl22	213	21	Pathogenesis	Pathogenesis	NNP
cord-330553-sukrjl22	213	22	and	and	CC
cord-330553-sukrjl22	213	23	Immunity	Immunity	NNP
cord-330553-sukrjl22	213	24	of	of	IN
cord-330553-sukrjl22	213	25	WNV	WNV	NNP
cord-330553-sukrjl22	213	26	Toll	Toll	NNP
cord-330553-sukrjl22	213	27	-	-	HYPH
cord-330553-sukrjl22	213	28	like	like	JJ
cord-330553-sukrjl22	213	29	receptor	receptor	NN
cord-330553-sukrjl22	213	30	3	3	CD
cord-330553-sukrjl22	214	1	mediates	mediate	VBZ
cord-330553-sukrjl22	214	2	West	West	NNP
cord-330553-sukrjl22	214	3	Nile	Nile	NNP
cord-330553-sukrjl22	214	4	virus	virus	NN
cord-330553-sukrjl22	214	5	entry	entry	NN
cord-330553-sukrjl22	214	6	into	into	IN
cord-330553-sukrjl22	214	7	the	the	DT
cord-330553-sukrjl22	214	8	brain	brain	NN
cord-330553-sukrjl22	214	9	causing	cause	VBG
cord-330553-sukrjl22	214	10	lethal	lethal	JJ
cord-330553-sukrjl22	214	11	encephalitis	encephalitis	RB
cord-330553-sukrjl22	215	1	The	the	DT
cord-330553-sukrjl22	215	2	Essential	Essential	NNP
cord-330553-sukrjl22	215	3	,	,	,
cord-330553-sukrjl22	215	4	Nonredundant	Nonredundant	NNP
cord-330553-sukrjl22	215	5	Roles	Roles	NNPS
cord-330553-sukrjl22	215	6	of	of	IN
cord-330553-sukrjl22	215	7	RIG	rig	NN
cord-330553-sukrjl22	215	8	-	-	:
cord-330553-sukrjl22	215	9	I	I	NNP
cord-330553-sukrjl22	215	10	and	and	CC
cord-330553-sukrjl22	215	11	MDA5	MDA5	NNP
cord-330553-sukrjl22	215	12	in	in	IN
cord-330553-sukrjl22	215	13	Detecting	detect	VBG
cord-330553-sukrjl22	215	14	and	and	CC
cord-330553-sukrjl22	215	15	Controlling	control	VBG
cord-330553-sukrjl22	215	16	West	West	NNP
cord-330553-sukrjl22	215	17	Nile	Nile	NNP
cord-330553-sukrjl22	215	18	Virus	Virus	NNP
cord-330553-sukrjl22	215	19	Infection	infection	NN
cord-330553-sukrjl22	215	20	Distinct	Distinct	NNP
cord-330553-sukrjl22	215	21	RIG	rig	NN
cord-330553-sukrjl22	215	22	-	-	:
cord-330553-sukrjl22	215	23	I	I	NNP
cord-330553-sukrjl22	215	24	and	and	CC
cord-330553-sukrjl22	215	25	MDA5	MDA5	NNP
cord-330553-sukrjl22	216	1	Signaling	signal	VBG
cord-330553-sukrjl22	216	2	by	by	IN
cord-330553-sukrjl22	216	3	RNA	RNA	NNP
cord-330553-sukrjl22	216	4	Viruses	Viruses	NNPS
cord-330553-sukrjl22	216	5	in	in	IN
cord-330553-sukrjl22	216	6	Innate	Innate	NNP
cord-330553-sukrjl22	216	7	Immunity	Immunity	NNP
cord-330553-sukrjl22	216	8	Characterization	characterization	NN
cord-330553-sukrjl22	216	9	of	of	IN
cord-330553-sukrjl22	216	10	retinoic	retinoic	JJ
cord-330553-sukrjl22	216	11	acid	acid	NN
cord-330553-sukrjl22	216	12	-	-	HYPH
cord-330553-sukrjl22	216	13	inducible	inducible	JJ
cord-330553-sukrjl22	216	14	gene	gene	NN
cord-330553-sukrjl22	216	15	-	-	:
cord-330553-sukrjl22	216	16	I	-PRON-	PRP
cord-330553-sukrjl22	216	17	expression	expression	NN
cord-330553-sukrjl22	216	18	in	in	IN
cord-330553-sukrjl22	216	19	primary	primary	JJ
cord-330553-sukrjl22	216	20	murine	murine	JJ
cord-330553-sukrjl22	216	21	glia	glia	NN
cord-330553-sukrjl22	216	22	following	follow	VBG
cord-330553-sukrjl22	216	23	exposure	exposure	NN
cord-330553-sukrjl22	216	24	to	to	IN
cord-330553-sukrjl22	216	25	vesicular	vesicular	JJ
cord-330553-sukrjl22	216	26	stomatitis	stomatitis	NN
cord-330553-sukrjl22	216	27	virus	virus	NN
cord-330553-sukrjl22	216	28	MAVS	MAVS	NNP
cord-330553-sukrjl22	216	29	Expressed	express	VBN
cord-330553-sukrjl22	216	30	by	by	IN
cord-330553-sukrjl22	216	31	Hematopoietic	Hematopoietic	NNP
cord-330553-sukrjl22	216	32	Cells	Cells	NNP
cord-330553-sukrjl22	217	1	Is	be	VBZ
cord-330553-sukrjl22	217	2	Critical	Critical	NNP
cord-330553-sukrjl22	217	3	for	for	IN
cord-330553-sukrjl22	217	4	Control	Control	NNP
cord-330553-sukrjl22	217	5	of	of	IN
cord-330553-sukrjl22	217	6	West	West	NNP
cord-330553-sukrjl22	217	7	Nile	Nile	NNP
cord-330553-sukrjl22	217	8	Virus	Virus	NNP
cord-330553-sukrjl22	217	9	Infection	Infection	NNP
cord-330553-sukrjl22	217	10	and	and	CC
cord-330553-sukrjl22	217	11	Pathogenesis	Pathogenesis	NNP
cord-330553-sukrjl22	218	1	IL-34	IL-34	NNP
cord-330553-sukrjl22	218	2	is	be	VBZ
cord-330553-sukrjl22	218	3	a	a	DT
cord-330553-sukrjl22	218	4	tissue	tissue	NN
cord-330553-sukrjl22	218	5	-	-	HYPH
cord-330553-sukrjl22	218	6	restricted	restrict	VBN
cord-330553-sukrjl22	218	7	ligand	ligand	NN
cord-330553-sukrjl22	218	8	of	of	IN
cord-330553-sukrjl22	218	9	CSF1R	CSF1R	NNS
cord-330553-sukrjl22	218	10	required	require	VBN
cord-330553-sukrjl22	218	11	for	for	IN
cord-330553-sukrjl22	218	12	the	the	DT
cord-330553-sukrjl22	218	13	development	development	NN
cord-330553-sukrjl22	218	14	of	of	IN
cord-330553-sukrjl22	218	15	Langerhans	Langerhans	NNP
cord-330553-sukrjl22	218	16	cells	cell	NNS
cord-330553-sukrjl22	218	17	and	and	CC
cord-330553-sukrjl22	218	18	microglia	microglia	NN
cord-330553-sukrjl22	218	19	CSF1R	CSF1R	NNS
cord-330553-sukrjl22	219	1	Ligands	Ligands	NNP
cord-330553-sukrjl22	220	1	IL-34	IL-34	NNP
cord-330553-sukrjl22	220	2	and	and	CC
cord-330553-sukrjl22	220	3	CSF1	CSF1	NNP
cord-330553-sukrjl22	220	4	Are	be	VBP
cord-330553-sukrjl22	220	5	Differentially	differentially	RB
cord-330553-sukrjl22	220	6	Required	require	VBN
cord-330553-sukrjl22	220	7	for	for	IN
cord-330553-sukrjl22	220	8	Microglia	Microglia	NNP
cord-330553-sukrjl22	220	9	Development	Development	NNP
cord-330553-sukrjl22	220	10	and	and	CC
cord-330553-sukrjl22	220	11	Maintenance	Maintenance	NNP
cord-330553-sukrjl22	220	12	in	in	IN
cord-330553-sukrjl22	220	13	White	White	NNP
cord-330553-sukrjl22	220	14	and	and	CC
cord-330553-sukrjl22	220	15	Gray	Gray	NNP
cord-330553-sukrjl22	220	16	Matter	Matter	NNP
cord-330553-sukrjl22	221	1	Brain	Brain	NNP
cord-330553-sukrjl22	221	2	Regions	Regions	NNPS
cord-330553-sukrjl22	221	3	CSF-1	CSF-1	NNP
cord-330553-sukrjl22	221	4	controls	control	VBZ
cord-330553-sukrjl22	221	5	cerebellar	cerebellar	JJ
cord-330553-sukrjl22	221	6	microglia	microglia	NNS
cord-330553-sukrjl22	221	7	and	and	CC
cord-330553-sukrjl22	221	8	is	be	VBZ
cord-330553-sukrjl22	221	9	required	require	VBN
cord-330553-sukrjl22	221	10	for	for	IN
cord-330553-sukrjl22	222	1	motor	motor	NN
cord-330553-sukrjl22	222	2	function	function	NN
cord-330553-sukrjl22	222	3	and	and	CC
cord-330553-sukrjl22	222	4	social	social	JJ
cord-330553-sukrjl22	222	5	interaction	interaction	NN
cord-330553-sukrjl22	222	6	Colony	Colony	NNP
cord-330553-sukrjl22	222	7	-	-	HYPH
cord-330553-sukrjl22	222	8	stimulating	stimulate	VBG
cord-330553-sukrjl22	222	9	factor	factor	NN
cord-330553-sukrjl22	222	10	1	1	CD
cord-330553-sukrjl22	222	11	receptor	receptor	NN
cord-330553-sukrjl22	222	12	inhibition	inhibition	NN
cord-330553-sukrjl22	222	13	prevents	prevent	VBZ
cord-330553-sukrjl22	222	14	microglial	microglial	NNP
cord-330553-sukrjl22	222	15	plaque	plaque	NNP
cord-330553-sukrjl22	222	16	association	association	NNP
cord-330553-sukrjl22	222	17	and	and	CC
cord-330553-sukrjl22	222	18	improves	improve	VBZ
cord-330553-sukrjl22	222	19	cognition	cognition	NN
cord-330553-sukrjl22	222	20	in	in	IN
cord-330553-sukrjl22	222	21	3xTg	3xtg	CD
cord-330553-sukrjl22	222	22	-	-	HYPH
cord-330553-sukrjl22	222	23	AD	ad	NN
cord-330553-sukrjl22	222	24	mice	mice	NN
cord-330553-sukrjl22	222	25	CSF1	CSF1	NNP
cord-330553-sukrjl22	222	26	receptor	receptor	NN
cord-330553-sukrjl22	222	27	signaling	signaling	NN
cord-330553-sukrjl22	222	28	is	be	VBZ
cord-330553-sukrjl22	222	29	necessary	necessary	JJ
cord-330553-sukrjl22	222	30	for	for	IN
cord-330553-sukrjl22	222	31	microglia	microglia	JJ
cord-330553-sukrjl22	222	32	viability	viability	NN
cord-330553-sukrjl22	222	33	,	,	,
cord-330553-sukrjl22	222	34	which	which	WDT
cord-330553-sukrjl22	222	35	unmasks	unmask	VBZ
cord-330553-sukrjl22	222	36	a	a	DT
cord-330553-sukrjl22	222	37	cell	cell	NN
cord-330553-sukrjl22	222	38	that	that	WDT
cord-330553-sukrjl22	222	39	rapidly	rapidly	RB
cord-330553-sukrjl22	222	40	repopulates	repopulate	VBZ
cord-330553-sukrjl22	222	41	the	the	DT
cord-330553-sukrjl22	222	42	microglia	microglia	NN
cord-330553-sukrjl22	222	43	-	-	HYPH
cord-330553-sukrjl22	222	44	depleted	deplete	VBN
cord-330553-sukrjl22	222	45	adult	adult	NN
cord-330553-sukrjl22	222	46	brain	brain	NN
cord-330553-sukrjl22	223	1	Matrix	Matrix	NNP
cord-330553-sukrjl22	223	2	Metalloproteinase	Metalloproteinase	NNP
cord-330553-sukrjl22	223	3	9	9	CD
cord-330553-sukrjl22	223	4	Facilitates	facilitate	VBZ
cord-330553-sukrjl22	223	5	West	West	NNP
cord-330553-sukrjl22	223	6	Nile	Nile	NNP
cord-330553-sukrjl22	223	7	Virus	Virus	NNP
cord-330553-sukrjl22	223	8	Entry	Entry	NNP
cord-330553-sukrjl22	223	9	into	into	IN
cord-330553-sukrjl22	223	10	the	the	DT
cord-330553-sukrjl22	223	11	Brain	Brain	NNP
cord-330553-sukrjl22	224	1	The	the	DT
cord-330553-sukrjl22	224	2	Role	role	NN
cord-330553-sukrjl22	224	3	of	of	IN
cord-330553-sukrjl22	224	4	Microglia	Microglia	NNP
cord-330553-sukrjl22	224	5	and	and	CC
cord-330553-sukrjl22	224	6	Matrix	Matrix	NNP
cord-330553-sukrjl22	224	7	Metalloproteinases	Metalloproteinases	NNP
cord-330553-sukrjl22	224	8	Involvement	Involvement	NNP
cord-330553-sukrjl22	224	9	in	in	IN
cord-330553-sukrjl22	224	10	Neuroinflammation	Neuroinflammation	NNP
cord-330553-sukrjl22	224	11	and	and	CC
cord-330553-sukrjl22	224	12	Gliomas	Gliomas	NNP
cord-330553-sukrjl22	224	13	Matrix	Matrix	NNP
cord-330553-sukrjl22	224	14	metalloproteinases	metalloproteinase	NNS
cord-330553-sukrjl22	224	15	as	as	IN
cord-330553-sukrjl22	224	16	modulators	modulator	NNS
cord-330553-sukrjl22	224	17	of	of	IN
cord-330553-sukrjl22	224	18	inflammation	inflammation	NN
cord-330553-sukrjl22	224	19	and	and	CC
cord-330553-sukrjl22	224	20	innate	innate	JJ
cord-330553-sukrjl22	224	21	immunity	immunity	NN
cord-330553-sukrjl22	224	22	Intercellular	Intercellular	NNP
cord-330553-sukrjl22	224	23	adhesion	adhesion	NN
cord-330553-sukrjl22	224	24	molecule-1	molecule-1	NNP
cord-330553-sukrjl22	224	25	gene	gene	NN
cord-330553-sukrjl22	224	26	expression	expression	NN
cord-330553-sukrjl22	224	27	by	by	IN
cord-330553-sukrjl22	224	28	glial	glial	JJ
cord-330553-sukrjl22	224	29	cells	cell	NNS
cord-330553-sukrjl22	224	30	.	.	.
cord-330553-sukrjl22	225	1	Differential	differential	JJ
cord-330553-sukrjl22	225	2	mechanisms	mechanism	NNS
cord-330553-sukrjl22	225	3	of	of	IN
cord-330553-sukrjl22	225	4	inhibition	inhibition	NN
cord-330553-sukrjl22	225	5	by	by	IN
cord-330553-sukrjl22	226	1	IL-10	IL-10	NNP
cord-330553-sukrjl22	226	2	and	and	CC
cord-330553-sukrjl22	226	3	IL-6	IL-6	NNP
cord-330553-sukrjl22	226	4	Dual	dual	JJ
cord-330553-sukrjl22	226	5	microglia	microglia	JJ
cord-330553-sukrjl22	226	6	effects	effect	NNS
cord-330553-sukrjl22	226	7	on	on	IN
cord-330553-sukrjl22	226	8	blood	blood	NN
cord-330553-sukrjl22	226	9	brain	brain	NN
cord-330553-sukrjl22	226	10	barrier	barrier	NN
cord-330553-sukrjl22	226	11	permeability	permeability	NN
cord-330553-sukrjl22	226	12	induced	induce	VBN
cord-330553-sukrjl22	226	13	by	by	IN
cord-330553-sukrjl22	226	14	systemic	systemic	JJ
cord-330553-sukrjl22	226	15	inflammation	inflammation	NN
cord-330553-sukrjl22	226	16	West	West	NNP
cord-330553-sukrjl22	226	17	Nile	Nile	NNP
cord-330553-sukrjl22	227	1	Virus	virus	NN
cord-330553-sukrjl22	227	2	-	-	HYPH
cord-330553-sukrjl22	227	3	Induced	induce	VBN
cord-330553-sukrjl22	227	4	Cell	cell	NN
cord-330553-sukrjl22	227	5	Adhesion	adhesion	NN
cord-330553-sukrjl22	227	6	Molecules	Molecules	NNPS
cord-330553-sukrjl22	227	7	on	on	IN
cord-330553-sukrjl22	227	8	Human	Human	NNP
cord-330553-sukrjl22	227	9	Brain	Brain	NNP
cord-330553-sukrjl22	227	10	Microvascular	Microvascular	NNP
cord-330553-sukrjl22	227	11	Endothelial	endothelial	NN
cord-330553-sukrjl22	227	12	Cells	cell	NNS
cord-330553-sukrjl22	227	13	Regulate	regulate	VBP
cord-330553-sukrjl22	227	14	Leukocyte	Leukocyte	NNP
cord-330553-sukrjl22	227	15	Adhesion	Adhesion	NNP
cord-330553-sukrjl22	227	16	and	and	CC
cord-330553-sukrjl22	227	17	Modulate	modulate	VBP
cord-330553-sukrjl22	227	18	Permeability	permeability	NN
cord-330553-sukrjl22	227	19	of	of	IN
cord-330553-sukrjl22	227	20	the	the	DT
cord-330553-sukrjl22	227	21	In	in	IN
cord-330553-sukrjl22	227	22	Vitro	Vitro	NNP
cord-330553-sukrjl22	227	23	Blood	Blood	NNP
cord-330553-sukrjl22	227	24	-	-	HYPH
cord-330553-sukrjl22	227	25	Brain	Brain	NNP
cord-330553-sukrjl22	227	26	Barrier	Barrier	NNP
cord-330553-sukrjl22	227	27	Model	Model	NNP
cord-330553-sukrjl22	227	28	T	T	NNP
cord-330553-sukrjl22	227	29	cells	cell	NNS
cord-330553-sukrjl22	227	30	promote	promote	VBP
cord-330553-sukrjl22	227	31	microglia	microglia	NN
cord-330553-sukrjl22	227	32	-	-	HYPH
cord-330553-sukrjl22	227	33	mediated	mediate	VBN
cord-330553-sukrjl22	227	34	synaptic	synaptic	JJ
cord-330553-sukrjl22	227	35	elimination	elimination	NN
cord-330553-sukrjl22	227	36	and	and	CC
cord-330553-sukrjl22	227	37	cognitive	cognitive	JJ
cord-330553-sukrjl22	227	38	dysfunction	dysfunction	NN
cord-330553-sukrjl22	227	39	during	during	IN
cord-330553-sukrjl22	227	40	recovery	recovery	NN
cord-330553-sukrjl22	227	41	from	from	IN
cord-330553-sukrjl22	227	42	neuropathogenic	neuropathogenic	NNP
cord-330553-sukrjl22	227	43	flaviviruses	flaviviruses	NNP
cord-330553-sukrjl22	228	1	A	a	DT
cord-330553-sukrjl22	228	2	complement	complement	NN
cord-330553-sukrjl22	228	3	-	-	HYPH
cord-330553-sukrjl22	228	4	microglial	microglial	JJ
cord-330553-sukrjl22	228	5	axis	axis	NN
cord-330553-sukrjl22	228	6	drives	drive	VBZ
cord-330553-sukrjl22	228	7	synapse	synapse	NN
cord-330553-sukrjl22	228	8	loss	loss	NN
cord-330553-sukrjl22	228	9	during	during	IN
cord-330553-sukrjl22	228	10	virus	virus	NN
cord-330553-sukrjl22	228	11	-	-	HYPH
cord-330553-sukrjl22	228	12	induced	induce	VBN
cord-330553-sukrjl22	228	13	memory	memory	NN
cord-330553-sukrjl22	228	14	impairment	impairment	NN
cord-330553-sukrjl22	229	1	To	to	TO
cord-330553-sukrjl22	229	2	Go	go	VB
cord-330553-sukrjl22	229	3	or	or	CC
cord-330553-sukrjl22	229	4	Stay	stay	VB
cord-330553-sukrjl22	229	5	:	:	:
cord-330553-sukrjl22	229	6	The	the	DT
cord-330553-sukrjl22	229	7	Development	Development	NNP
cord-330553-sukrjl22	229	8	,	,	,
cord-330553-sukrjl22	229	9	Benefit	Benefit	NNP
cord-330553-sukrjl22	229	10	,	,	,
cord-330553-sukrjl22	229	11	and	and	CC
cord-330553-sukrjl22	229	12	Detriment	detriment	NN
cord-330553-sukrjl22	229	13	of	of	IN
cord-330553-sukrjl22	229	14	Tissue	tissue	NN
cord-330553-sukrjl22	229	15	-	-	HYPH
cord-330553-sukrjl22	229	16	Resident	Resident	NNP
cord-330553-sukrjl22	229	17	Memory	Memory	NNP
cord-330553-sukrjl22	229	18	CD8	CD8	NNP
cord-330553-sukrjl22	229	19	T	T	NNP
cord-330553-sukrjl22	229	20	Cells	cell	NNS
cord-330553-sukrjl22	229	21	during	during	IN
cord-330553-sukrjl22	229	22	Central	central	JJ
cord-330553-sukrjl22	229	23	Nervous	Nervous	NNP
cord-330553-sukrjl22	229	24	System	system	NN
cord-330553-sukrjl22	229	25	Viral	viral	JJ
cord-330553-sukrjl22	229	26	Infections	Infections	NNPS
cord-330553-sukrjl22	229	27	Update	update	VBP
cord-330553-sukrjl22	229	28	on	on	IN
cord-330553-sukrjl22	229	29	T	T	NNP
cord-330553-sukrjl22	229	30	cells	cell	NNS
cord-330553-sukrjl22	229	31	in	in	IN
cord-330553-sukrjl22	229	32	the	the	DT
cord-330553-sukrjl22	229	33	virally	virally	RB
cord-330553-sukrjl22	229	34	infected	infect	VBN
cord-330553-sukrjl22	229	35	brain	brain	NN
cord-330553-sukrjl22	229	36	:	:	:
cord-330553-sukrjl22	230	1	Friends	friend	NNS
cord-330553-sukrjl22	230	2	and	and	CC
cord-330553-sukrjl22	230	3	foes	foe	NNS
cord-330553-sukrjl22	230	4	CD4	CD4	NNP
cord-330553-sukrjl22	230	5	+	+	CC
cord-330553-sukrjl22	230	6	T	T	NNP
cord-330553-sukrjl22	230	7	-	-	HYPH
cord-330553-sukrjl22	230	8	Cell	cell	NN
cord-330553-sukrjl22	230	9	Responses	response	NNS
cord-330553-sukrjl22	230	10	Are	be	VBP
cord-330553-sukrjl22	230	11	Required	require	VBN
cord-330553-sukrjl22	230	12	for	for	IN
cord-330553-sukrjl22	230	13	Clearance	Clearance	NNP
cord-330553-sukrjl22	230	14	of	of	IN
cord-330553-sukrjl22	230	15	West	West	NNP
cord-330553-sukrjl22	230	16	Nile	Nile	NNP
cord-330553-sukrjl22	230	17	Virus	Virus	NNP
cord-330553-sukrjl22	230	18	from	from	IN
cord-330553-sukrjl22	230	19	the	the	DT
cord-330553-sukrjl22	230	20	Central	Central	NNP
cord-330553-sukrjl22	230	21	Nervous	Nervous	NNP
cord-330553-sukrjl22	230	22	System	System	NNP
cord-330553-sukrjl22	230	23	Microglia	Microglia	NNP
cord-330553-sukrjl22	230	24	in	in	IN
cord-330553-sukrjl22	230	25	Memory	memory	NN
cord-330553-sukrjl22	230	26	Decline	Decline	NNP
cord-330553-sukrjl22	230	27	from	from	IN
cord-330553-sukrjl22	230	28	Zika	Zika	NNP
cord-330553-sukrjl22	230	29	Virus	Virus	NNP
cord-330553-sukrjl22	230	30	and	and	CC
cord-330553-sukrjl22	231	1	West	West	NNP
cord-330553-sukrjl22	231	2	Nile	Nile	NNP
cord-330553-sukrjl22	231	3	Virus	Virus	NNP
cord-330553-sukrjl22	231	4	Infection	infection	NN
cord-330553-sukrjl22	232	1	The	the	DT
cord-330553-sukrjl22	232	2	role	role	NN
cord-330553-sukrjl22	232	3	of	of	IN
cord-330553-sukrjl22	232	4	microglia	microglia	NN
cord-330553-sukrjl22	232	5	in	in	IN
cord-330553-sukrjl22	232	6	viral	viral	JJ
cord-330553-sukrjl22	232	7	encephalitis	encephalitis	NN
cord-330553-sukrjl22	232	8	:	:	:
cord-330553-sukrjl22	233	1	A	a	DT
cord-330553-sukrjl22	233	2	review	review	NN
cord-330553-sukrjl22	233	3	The	the	DT
cord-330553-sukrjl22	233	4	Complement	Complement	NNP
cord-330553-sukrjl22	233	5	System	System	NNP
cord-330553-sukrjl22	233	6	:	:	:
cord-330553-sukrjl22	233	7	An	an	DT
cord-330553-sukrjl22	233	8	Unexpected	unexpected	JJ
cord-330553-sukrjl22	233	9	Role	role	NN
cord-330553-sukrjl22	233	10	in	in	IN
cord-330553-sukrjl22	233	11	Synaptic	synaptic	JJ
cord-330553-sukrjl22	233	12	Pruning	Pruning	NNP
cord-330553-sukrjl22	233	13	During	during	IN
cord-330553-sukrjl22	233	14	Development	Development	NNP
cord-330553-sukrjl22	233	15	and	and	CC
cord-330553-sukrjl22	233	16	Disease	Disease	NNP
cord-330553-sukrjl22	234	1	The	the	DT
cord-330553-sukrjl22	234	2	Classical	Classical	NNP
cord-330553-sukrjl22	234	3	Complement	Complement	NNP
cord-330553-sukrjl22	234	4	Cascade	Cascade	NNP
cord-330553-sukrjl22	234	5	Mediates	mediate	VBZ
cord-330553-sukrjl22	235	1	CNS	CNS	NNP
cord-330553-sukrjl22	235	2	Synapse	Synapse	NNP
cord-330553-sukrjl22	235	3	Elimination	Elimination	NNP
cord-330553-sukrjl22	235	4	Microglia	Microglia	NNP
cord-330553-sukrjl22	235	5	Sculpt	sculpt	JJ
cord-330553-sukrjl22	235	6	Postnatal	postnatal	JJ
cord-330553-sukrjl22	235	7	Neural	neural	JJ
cord-330553-sukrjl22	235	8	Circuits	Circuits	NNPS
cord-330553-sukrjl22	235	9	in	in	IN
cord-330553-sukrjl22	235	10	an	an	DT
cord-330553-sukrjl22	235	11	Activity	Activity	NNP
cord-330553-sukrjl22	235	12	and	and	CC
cord-330553-sukrjl22	235	13	Complement	complement	NN
cord-330553-sukrjl22	235	14	-	-	HYPH
cord-330553-sukrjl22	235	15	Dependent	Dependent	NNP
cord-330553-sukrjl22	235	16	Manner	Manner	NNP
cord-330553-sukrjl22	235	17	Chapter	Chapter	NNP
cord-330553-sukrjl22	235	18	Two	two	CD
cord-330553-sukrjl22	235	19	-	-	HYPH
cord-330553-sukrjl22	235	20	Complement	Complement	NNP
cord-330553-sukrjl22	235	21	System	System	NNP
cord-330553-sukrjl22	235	22	in	in	IN
cord-330553-sukrjl22	235	23	Neural	Neural	NNP
cord-330553-sukrjl22	235	24	Synapse	Synapse	NNP
cord-330553-sukrjl22	235	25	Elimination	Elimination	NNP
cord-330553-sukrjl22	235	26	in	in	IN
cord-330553-sukrjl22	235	27	Development	Development	NNP
cord-330553-sukrjl22	235	28	and	and	CC
cord-330553-sukrjl22	235	29	Disease	Disease	NNP
cord-330553-sukrjl22	235	30	Granulocyte	Granulocyte	NNP
cord-330553-sukrjl22	235	31	Macrophage	Macrophage	NNP
cord-330553-sukrjl22	235	32	Colony	Colony	NNP
cord-330553-sukrjl22	235	33	Stimulating	Stimulating	NNP
cord-330553-sukrjl22	235	34	Factor	Factor	NNP
cord-330553-sukrjl22	235	35	Treatment	Treatment	NNP
cord-330553-sukrjl22	235	36	is	be	VBZ
cord-330553-sukrjl22	235	37	Associated	associate	VBN
cord-330553-sukrjl22	235	38	with	with	IN
cord-330553-sukrjl22	235	39	Improved	Improved	NNP
cord-330553-sukrjl22	235	40	Cognition	Cognition	NNP
cord-330553-sukrjl22	235	41	in	in	IN
cord-330553-sukrjl22	235	42	Cancer	Cancer	NNP
cord-330553-sukrjl22	235	43	Patients	Patients	NNP
cord-330553-sukrjl22	235	44	GM	GM	NNP
cord-330553-sukrjl22	235	45	-	-	HYPH
cord-330553-sukrjl22	235	46	CSF	CSF	NNP
cord-330553-sukrjl22	235	47	Upregulated	Upregulated	NNP
cord-330553-sukrjl22	235	48	in	in	IN
cord-330553-sukrjl22	235	49	Rheumatoid	Rheumatoid	NNP
cord-330553-sukrjl22	235	50	Arthritis	arthritis	NN
cord-330553-sukrjl22	235	51	Reverses	reverse	VBZ
cord-330553-sukrjl22	235	52	Cognitive	Cognitive	NNP
cord-330553-sukrjl22	235	53	Impairment	Impairment	NNP
cord-330553-sukrjl22	235	54	and	and	CC
cord-330553-sukrjl22	235	55	Amyloidosis	Amyloidosis	NNP
cord-330553-sukrjl22	235	56	in	in	IN
cord-330553-sukrjl22	235	57	Alzheimer	Alzheimer	NNP
cord-330553-sukrjl22	235	58	Mice	Mice	NNP
cord-330553-sukrjl22	236	1	The	the	DT
cord-330553-sukrjl22	236	2	Kaleidoscope	Kaleidoscope	NNP
cord-330553-sukrjl22	236	3	of	of	IN
cord-330553-sukrjl22	236	4	Microglial	Microglial	NNP
cord-330553-sukrjl22	236	5	Phenotypes	Phenotypes	NNP
cord-330553-sukrjl22	237	1	This	this	DT
cord-330553-sukrjl22	237	2	article	article	NN
cord-330553-sukrjl22	237	3	is	be	VBZ
cord-330553-sukrjl22	237	4	an	an	DT
cord-330553-sukrjl22	237	5	open	open	JJ
cord-330553-sukrjl22	237	6	access	access	NN
cord-330553-sukrjl22	237	7	article	article	NN
cord-330553-sukrjl22	237	8	distributed	distribute	VBN
cord-330553-sukrjl22	237	9	under	under	IN
cord-330553-sukrjl22	237	10	the	the	DT
cord-330553-sukrjl22	237	11	terms	term	NNS
cord-330553-sukrjl22	237	12	and	and	CC
cord-330553-sukrjl22	237	13	conditions	condition	NNS
cord-330553-sukrjl22	237	14	of	of	IN
cord-330553-sukrjl22	237	15	the	the	DT
cord-330553-sukrjl22	237	16	Creative	Creative	NNP
cord-330553-sukrjl22	237	17	Commons	Commons	NNP
cord-330553-sukrjl22	237	18	Attribution	Attribution	NNP
cord-330553-sukrjl22	237	19	(	(	-LRB-
cord-330553-sukrjl22	237	20	CC	CC	NNP
cord-330553-sukrjl22	237	21	BY	by	IN
cord-330553-sukrjl22	237	22	)	)	-RRB-
cord-330553-sukrjl22	237	23	license	license	NN
cord-330553-sukrjl22	238	1	The	the	DT
cord-330553-sukrjl22	238	2	authors	author	NNS
cord-330553-sukrjl22	238	3	declare	declare	VBP
cord-330553-sukrjl22	238	4	no	no	DT
cord-330553-sukrjl22	238	5	conflict	conflict	NN
cord-330553-sukrjl22	238	6	of	of	IN
cord-330553-sukrjl22	238	7	interest	interest	NN
cord-330553-sukrjl22	238	8	.	.	.
cord-330553-sukrjl22	239	1	Vaccines	vaccine	NNS
cord-330553-sukrjl22	239	2	2020	2020	CD
cord-330553-sukrjl22	239	3	,	,	,
cord-330553-sukrjl22	239	4	8	8	CD
cord-330553-sukrjl22	239	5	,	,	,
cord-330553-sukrjl22	239	6	485	485	CD
cord-330553-sukrjl22	239	7	 	 	_SP