id	sid	tid	token	lemma	pos
cord-355413-ls2nud43	1	1	key	key	NN
cord-355413-ls2nud43	1	2	:	:	:
cord-355413-ls2nud43	2	1	cord-355413-ls2nud43	cord-355413-ls2nud43	JJ
cord-355413-ls2nud43	2	2	authors	author	NNS
cord-355413-ls2nud43	2	3	:	:	:
cord-355413-ls2nud43	2	4	Shi	Shi	NNP
cord-355413-ls2nud43	2	5	,	,	,
cord-355413-ls2nud43	2	6	Fu	Fu	NNP
cord-355413-ls2nud43	2	7	-	-	HYPH
cord-355413-ls2nud43	2	8	Dong	Dong	NNP
cord-355413-ls2nud43	2	9	;	;	:
cord-355413-ls2nud43	2	10	Ransohoff	Ransohoff	NNP
cord-355413-ls2nud43	2	11	,	,	,
cord-355413-ls2nud43	2	12	Richard	Richard	NNP
cord-355413-ls2nud43	2	13	M.	M.	NNP
cord-355413-ls2nud43	3	1	title	title	NN
cord-355413-ls2nud43	3	2	:	:	:
cord-355413-ls2nud43	4	1	Nature	nature	NN
cord-355413-ls2nud43	4	2	killer	killer	NN
cord-355413-ls2nud43	4	3	cells	cell	NNS
cord-355413-ls2nud43	4	4	in	in	IN
cord-355413-ls2nud43	4	5	the	the	DT
cord-355413-ls2nud43	4	6	central	central	JJ
cord-355413-ls2nud43	4	7	nervous	nervous	JJ
cord-355413-ls2nud43	4	8	system	system	NN
cord-355413-ls2nud43	4	9	date	date	NN
cord-355413-ls2nud43	5	1	:	:	:
cord-355413-ls2nud43	5	2	2010	2010	CD
cord-355413-ls2nud43	5	3	-	-	SYM
cord-355413-ls2nud43	5	4	01	01	CD
cord-355413-ls2nud43	5	5	-	-	HYPH
cord-355413-ls2nud43	5	6	29	29	CD
cord-355413-ls2nud43	5	7	journal	journal	NN
cord-355413-ls2nud43	5	8	:	:	:
cord-355413-ls2nud43	6	1	Natural	Natural	NNP
cord-355413-ls2nud43	6	2	Killer	Killer	NNP
cord-355413-ls2nud43	6	3	Cells	cell	NNS
cord-355413-ls2nud43	6	4	DOI	DOI	NNP
cord-355413-ls2nud43	6	5	:	:	:
cord-355413-ls2nud43	6	6	10.1016	10.1016	CD
cord-355413-ls2nud43	6	7	/	/	SYM
cord-355413-ls2nud43	6	8	b978	b978	NN
cord-355413-ls2nud43	6	9	-	-	HYPH
cord-355413-ls2nud43	6	10	0	0	CD
cord-355413-ls2nud43	6	11	-	-	HYPH
cord-355413-ls2nud43	6	12	12	12	CD
cord-355413-ls2nud43	6	13	-	-	HYPH
cord-355413-ls2nud43	6	14	370454	370454	CD
cord-355413-ls2nud43	6	15	-	-	HYPH
cord-355413-ls2nud43	6	16	2.00028	2.00028	CD
cord-355413-ls2nud43	6	17	-	-	SYM
cord-355413-ls2nud43	6	18	4	4	CD
cord-355413-ls2nud43	6	19	sha	sha	NNP
cord-355413-ls2nud43	6	20	:	:	:
cord-355413-ls2nud43	7	1	e94b06a5ff796595f1ba5d07fd544145f7d46fcc	e94b06a5ff796595f1ba5d07fd544145f7d46fcc	NNS
cord-355413-ls2nud43	7	2	doc_id	doc_id	CD
cord-355413-ls2nud43	7	3	:	:	:
cord-355413-ls2nud43	7	4	355413	355413	CD
cord-355413-ls2nud43	7	5	cord_uid	cord_uid	NNS
cord-355413-ls2nud43	7	6	:	:	:
cord-355413-ls2nud43	8	1	ls2nud43	ls2nud43	NNP
cord-355413-ls2nud43	8	2	Natural	natural	JJ
cord-355413-ls2nud43	8	3	killer	killer	NN
cord-355413-ls2nud43	8	4	(	(	-LRB-
cord-355413-ls2nud43	8	5	NK	NK	NNP
cord-355413-ls2nud43	8	6	)	)	-RRB-
cord-355413-ls2nud43	8	7	cells	cell	NNS
cord-355413-ls2nud43	8	8	,	,	,
cord-355413-ls2nud43	8	9	a	a	DT
cord-355413-ls2nud43	8	10	prominent	prominent	JJ
cord-355413-ls2nud43	8	11	component	component	NN
cord-355413-ls2nud43	8	12	of	of	IN
cord-355413-ls2nud43	8	13	the	the	DT
cord-355413-ls2nud43	8	14	innate	innate	JJ
cord-355413-ls2nud43	8	15	immune	immune	JJ
cord-355413-ls2nud43	8	16	system	system	NN
cord-355413-ls2nud43	8	17	,	,	,
cord-355413-ls2nud43	8	18	are	be	VBP
cord-355413-ls2nud43	8	19	large	large	JJ
cord-355413-ls2nud43	8	20	granular	granular	JJ
cord-355413-ls2nud43	8	21	lymphocytes	lymphocyte	NNS
cord-355413-ls2nud43	8	22	that	that	WDT
cord-355413-ls2nud43	8	23	respond	respond	VBP
cord-355413-ls2nud43	8	24	rapidly	rapidly	RB
cord-355413-ls2nud43	8	25	to	to	IN
cord-355413-ls2nud43	8	26	a	a	DT
cord-355413-ls2nud43	8	27	variety	variety	NN
cord-355413-ls2nud43	8	28	of	of	IN
cord-355413-ls2nud43	8	29	insults	insult	NNS
cord-355413-ls2nud43	8	30	via	via	IN
cord-355413-ls2nud43	8	31	cytokine	cytokine	JJ
cord-355413-ls2nud43	8	32	secretion	secretion	NN
cord-355413-ls2nud43	8	33	and	and	CC
cord-355413-ls2nud43	8	34	cytolytic	cytolytic	JJ
cord-355413-ls2nud43	8	35	activity	activity	NN
cord-355413-ls2nud43	8	36	.	.	.
cord-355413-ls2nud43	9	1	Recently	recently	RB
cord-355413-ls2nud43	9	2	,	,	,
cord-355413-ls2nud43	9	3	there	there	EX
cord-355413-ls2nud43	9	4	has	have	VBZ
cord-355413-ls2nud43	9	5	been	be	VBN
cord-355413-ls2nud43	9	6	growing	grow	VBG
cord-355413-ls2nud43	9	7	insight	insight	NN
cord-355413-ls2nud43	9	8	into	into	IN
cord-355413-ls2nud43	9	9	the	the	DT
cord-355413-ls2nud43	9	10	biological	biological	JJ
cord-355413-ls2nud43	9	11	functions	function	NNS
cord-355413-ls2nud43	9	12	of	of	IN
cord-355413-ls2nud43	9	13	NK	NK	NNP
cord-355413-ls2nud43	9	14	cells	cell	NNS
cord-355413-ls2nud43	9	15	,	,	,
cord-355413-ls2nud43	9	16	in	in	IN
cord-355413-ls2nud43	9	17	particular	particular	JJ
cord-355413-ls2nud43	9	18	into	into	IN
cord-355413-ls2nud43	9	19	their	-PRON-	PRP$
cord-355413-ls2nud43	9	20	roles	role	NNS
cord-355413-ls2nud43	9	21	in	in	IN
cord-355413-ls2nud43	9	22	infection	infection	NN
cord-355413-ls2nud43	9	23	,	,	,
cord-355413-ls2nud43	9	24	tumorurveillance	tumorurveillance	NN
cord-355413-ls2nud43	9	25	and	and	CC
cord-355413-ls2nud43	9	26	autoimmunity	autoimmunity	NN
cord-355413-ls2nud43	9	27	.	.	.
cord-355413-ls2nud43	10	1	Under	under	IN
cord-355413-ls2nud43	10	2	these	these	DT
cord-355413-ls2nud43	10	3	pathophysiological	pathophysiological	JJ
cord-355413-ls2nud43	10	4	circumstances	circumstance	NNS
cord-355413-ls2nud43	10	5	,	,	,
cord-355413-ls2nud43	10	6	NK	NK	NNP
cord-355413-ls2nud43	10	7	cells	cell	NNS
cord-355413-ls2nud43	10	8	readily	readily	RB
cord-355413-ls2nud43	10	9	home	home	RB
cord-355413-ls2nud43	10	10	to	to	IN
cord-355413-ls2nud43	10	11	the	the	DT
cord-355413-ls2nud43	10	12	central	central	JJ
cord-355413-ls2nud43	10	13	nervous	nervous	JJ
cord-355413-ls2nud43	10	14	system	system	NN
cord-355413-ls2nud43	10	15	(	(	-LRB-
cord-355413-ls2nud43	10	16	CNS	CNS	NNP
cord-355413-ls2nud43	10	17	)	)	-RRB-
cord-355413-ls2nud43	10	18	tissues	tissue	NNS
cord-355413-ls2nud43	10	19	to	to	TO
cord-355413-ls2nud43	10	20	combat	combat	VB
cord-355413-ls2nud43	10	21	infection	infection	NN
cord-355413-ls2nud43	10	22	and	and	CC
cord-355413-ls2nud43	10	23	presumably	presumably	RB
cord-355413-ls2nud43	10	24	to	to	TO
cord-355413-ls2nud43	10	25	curb	curb	VB
cord-355413-ls2nud43	10	26	progression	progression	NN
cord-355413-ls2nud43	10	27	of	of	IN
cord-355413-ls2nud43	10	28	tumor	tumor	NN
cord-355413-ls2nud43	10	29	.	.	.
cord-355413-ls2nud43	11	1	Bystander	bystander	NN
cord-355413-ls2nud43	11	2	neuronal	neuronal	JJ
cord-355413-ls2nud43	11	3	and/or	and/or	CC
cord-355413-ls2nud43	11	4	glial	glial	JJ
cord-355413-ls2nud43	11	5	cell	cell	NN
cord-355413-ls2nud43	11	6	damage	damage	NN
cord-355413-ls2nud43	11	7	can	can	MD
cord-355413-ls2nud43	11	8	occur	occur	VB
cord-355413-ls2nud43	11	9	in	in	IN
cord-355413-ls2nud43	11	10	this	this	DT
cord-355413-ls2nud43	11	11	setting	setting	NN
cord-355413-ls2nud43	11	12	.	.	.
cord-355413-ls2nud43	12	1	Paradoxically	paradoxically	RB
cord-355413-ls2nud43	12	2	,	,	,
cord-355413-ls2nud43	12	3	NK	NK	NNP
cord-355413-ls2nud43	12	4	cells	cell	NNS
cord-355413-ls2nud43	12	5	appear	appear	VBP
cord-355413-ls2nud43	12	6	to	to	TO
cord-355413-ls2nud43	12	7	have	have	VB
cord-355413-ls2nud43	12	8	an	an	DT
cord-355413-ls2nud43	12	9	inhibitory	inhibitory	JJ
cord-355413-ls2nud43	12	10	role	role	NN
cord-355413-ls2nud43	12	11	for	for	IN
cord-355413-ls2nud43	12	12	autoimmune	autoimmune	JJ
cord-355413-ls2nud43	12	13	responses	response	NNS
cord-355413-ls2nud43	12	14	within	within	IN
cord-355413-ls2nud43	12	15	the	the	DT
cord-355413-ls2nud43	12	16	CNS	CNS	NNP
cord-355413-ls2nud43	12	17	.	.	.
cord-355413-ls2nud43	13	1	As	as	IN
cord-355413-ls2nud43	13	2	in	in	IN
cord-355413-ls2nud43	13	3	the	the	DT
cord-355413-ls2nud43	13	4	periphery	periphery	NN
cord-355413-ls2nud43	13	5	,	,	,
cord-355413-ls2nud43	13	6	NK	NK	NNP
cord-355413-ls2nud43	13	7	cells	cell	NNS
cord-355413-ls2nud43	13	8	act	act	VBP
cord-355413-ls2nud43	13	9	in	in	IN
cord-355413-ls2nud43	13	10	concert	concert	NN
cord-355413-ls2nud43	13	11	with	with	IN
cord-355413-ls2nud43	13	12	T	T	NNP
cord-355413-ls2nud43	13	13	cells	cell	NNS
cord-355413-ls2nud43	13	14	and	and	CC
cord-355413-ls2nud43	13	15	other	other	JJ
cord-355413-ls2nud43	13	16	lymphocytes	lymphocyte	NNS
cord-355413-ls2nud43	13	17	responsible	responsible	JJ
cord-355413-ls2nud43	13	18	for	for	IN
cord-355413-ls2nud43	13	19	CNS	CNS	NNP
cord-355413-ls2nud43	13	20	pathology	pathology	NN
cord-355413-ls2nud43	13	21	and	and	CC
cord-355413-ls2nud43	13	22	immune	immune	JJ
cord-355413-ls2nud43	13	23	regulation	regulation	NN
cord-355413-ls2nud43	13	24	.	.	.
cord-355413-ls2nud43	14	1	Insights	insight	NNS
cord-355413-ls2nud43	14	2	into	into	IN
cord-355413-ls2nud43	14	3	the	the	DT
cord-355413-ls2nud43	14	4	molecular	molecular	JJ
cord-355413-ls2nud43	14	5	signals	signal	NNS
cord-355413-ls2nud43	14	6	and	and	CC
cord-355413-ls2nud43	14	7	pathways	pathway	NNS
cord-355413-ls2nud43	14	8	governing	govern	VBG
cord-355413-ls2nud43	14	9	the	the	DT
cord-355413-ls2nud43	14	10	diverse	diverse	JJ
cord-355413-ls2nud43	14	11	biological	biological	JJ
cord-355413-ls2nud43	14	12	effects	effect	NNS
cord-355413-ls2nud43	14	13	of	of	IN
cord-355413-ls2nud43	14	14	NK	NK	NNP
cord-355413-ls2nud43	14	15	cells	cell	NNS
cord-355413-ls2nud43	14	16	are	be	VBP
cord-355413-ls2nud43	14	17	keys	key	NNS
cord-355413-ls2nud43	14	18	for	for	IN
cord-355413-ls2nud43	14	19	designing	design	VBG
cord-355413-ls2nud43	14	20	NK	NK	NNP
cord-355413-ls2nud43	14	21	cell	cell	NN
cord-355413-ls2nud43	14	22	-	-	HYPH
cord-355413-ls2nud43	14	23	based	base	VBN
cord-355413-ls2nud43	14	24	therapy	therapy	NN
cord-355413-ls2nud43	14	25	for	for	IN
cord-355413-ls2nud43	14	26	CNS	CNS	NNP
cord-355413-ls2nud43	14	27	infections	infection	NNS
cord-355413-ls2nud43	14	28	,	,	,
cord-355413-ls2nud43	14	29	tumor	tumor	NN
cord-355413-ls2nud43	14	30	and	and	CC
cord-355413-ls2nud43	14	31	autoimmune	autoimmune	JJ
cord-355413-ls2nud43	14	32	diseases	disease	NNS
cord-355413-ls2nud43	14	33	.	.	.
cord-355413-ls2nud43	15	1	NK	NK	NNP
cord-355413-ls2nud43	15	2	cells	cell	NNS
cord-355413-ls2nud43	15	3	readily	readily	RB
cord-355413-ls2nud43	15	4	accumulate	accumulate	VBP
cord-355413-ls2nud43	15	5	in	in	IN
cord-355413-ls2nud43	15	6	homing	homing	NN
cord-355413-ls2nud43	15	7	to	to	IN
cord-355413-ls2nud43	15	8	CNS	CNS	NNP
cord-355413-ls2nud43	15	9	tissues	tissue	NNS
cord-355413-ls2nud43	15	10	under	under	IN
cord-355413-ls2nud43	15	11	the	the	DT
cord-355413-ls2nud43	15	12	pathophysiological	pathophysiological	JJ
cord-355413-ls2nud43	15	13	situations	situation	NNS
cord-355413-ls2nud43	15	14	.	.	.
cord-355413-ls2nud43	16	1	This	this	DT
cord-355413-ls2nud43	16	2	process	process	NN
cord-355413-ls2nud43	16	3	is	be	VBZ
cord-355413-ls2nud43	16	4	tightly	tightly	RB
cord-355413-ls2nud43	16	5	controlled	control	VBN
cord-355413-ls2nud43	16	6	by	by	IN
cord-355413-ls2nud43	16	7	a	a	DT
cord-355413-ls2nud43	16	8	number	number	NN
cord-355413-ls2nud43	16	9	of	of	IN
cord-355413-ls2nud43	16	10	chemokines	chemokine	NNS
cord-355413-ls2nud43	16	11	and	and	CC
cord-355413-ls2nud43	16	12	chemokine	chemokine	NN
cord-355413-ls2nud43	16	13	receptors	receptor	NNS
cord-355413-ls2nud43	16	14	.	.	.
cord-355413-ls2nud43	17	1	There	there	EX
cord-355413-ls2nud43	17	2	is	be	VBZ
cord-355413-ls2nud43	17	3	ample	ample	JJ
cord-355413-ls2nud43	17	4	of	of	IN
cord-355413-ls2nud43	17	5	evidence	evidence	NN
cord-355413-ls2nud43	17	6	that	that	IN
cord-355413-ls2nud43	17	7	NK	NK	NNP
cord-355413-ls2nud43	17	8	cells	cell	NNS
cord-355413-ls2nud43	17	9	within	within	IN
cord-355413-ls2nud43	17	10	the	the	DT
cord-355413-ls2nud43	17	11	CNS	CNS	NNP
cord-355413-ls2nud43	17	12	contribute	contribute	VBP
cord-355413-ls2nud43	17	13	to	to	IN
cord-355413-ls2nud43	17	14	the	the	DT
cord-355413-ls2nud43	17	15	control	control	NN
cord-355413-ls2nud43	17	16	of	of	IN
cord-355413-ls2nud43	17	17	infections	infection	NNS
cord-355413-ls2nud43	17	18	and	and	CC
cord-355413-ls2nud43	17	19	might	may	MD
cord-355413-ls2nud43	17	20	limit	limit	VB
cord-355413-ls2nud43	17	21	progression	progression	NN
cord-355413-ls2nud43	17	22	of	of	IN
cord-355413-ls2nud43	17	23	certain	certain	JJ
cord-355413-ls2nud43	17	24	tumor	tumor	NN
cord-355413-ls2nud43	17	25	.	.	.
cord-355413-ls2nud43	18	1	Bystander	bystander	NN
cord-355413-ls2nud43	18	2	neuronal	neuronal	JJ
cord-355413-ls2nud43	18	3	and/or	and/or	CC
cord-355413-ls2nud43	18	4	glial	glial	JJ
cord-355413-ls2nud43	18	5	cell	cell	NN
cord-355413-ls2nud43	18	6	damage	damage	NN
cord-355413-ls2nud43	18	7	can	can	MD
cord-355413-ls2nud43	18	8	occur	occur	VB
cord-355413-ls2nud43	18	9	.	.	.
cord-355413-ls2nud43	19	1	In	in	IN
cord-355413-ls2nud43	19	2	certain	certain	JJ
cord-355413-ls2nud43	19	3	autoimmune	autoimmune	JJ
cord-355413-ls2nud43	19	4	conditions	condition	NNS
cord-355413-ls2nud43	19	5	of	of	IN
cord-355413-ls2nud43	19	6	the	the	DT
cord-355413-ls2nud43	19	7	CNS	CNS	NNP
cord-355413-ls2nud43	19	8	,	,	,
cord-355413-ls2nud43	19	9	NK	NK	NNP
cord-355413-ls2nud43	19	10	cells	cell	NNS
cord-355413-ls2nud43	19	11	appear	appear	VBP
cord-355413-ls2nud43	19	12	to	to	TO
cord-355413-ls2nud43	19	13	have	have	VB
cord-355413-ls2nud43	19	14	an	an	DT
cord-355413-ls2nud43	19	15	inhibitory	inhibitory	JJ
cord-355413-ls2nud43	19	16	role	role	NN
cord-355413-ls2nud43	19	17	.	.	.
cord-355413-ls2nud43	20	1	Disassociation	disassociation	NN
cord-355413-ls2nud43	20	2	of	of	IN
cord-355413-ls2nud43	20	3	disease	disease	NN
cord-355413-ls2nud43	20	4	-	-	HYPH
cord-355413-ls2nud43	20	5	inhibiting	inhibit	VBG
cord-355413-ls2nud43	20	6	versus	versus	IN
cord-355413-ls2nud43	20	7	disease	disease	NN
cord-355413-ls2nud43	20	8	-	-	HYPH
cord-355413-ls2nud43	20	9	promoting	promote	VBG
cord-355413-ls2nud43	20	10	effects	effect	NNS
cord-355413-ls2nud43	20	11	of	of	IN
cord-355413-ls2nud43	20	12	NK	NK	NNP
cord-355413-ls2nud43	20	13	cells	cell	NNS
cord-355413-ls2nud43	20	14	is	be	VBZ
cord-355413-ls2nud43	20	15	a	a	DT
cord-355413-ls2nud43	20	16	key	key	NN
cord-355413-ls2nud43	20	17	to	to	IN
cord-355413-ls2nud43	20	18	harnessing	harness	VBG
cord-355413-ls2nud43	20	19	NK	NK	NNP
cord-355413-ls2nud43	20	20	cells	cell	NNS
cord-355413-ls2nud43	20	21	for	for	IN
cord-355413-ls2nud43	20	22	therapeutic	therapeutic	JJ
cord-355413-ls2nud43	20	23	purposes	purpose	NNS
cord-355413-ls2nud43	20	24	.	.	.
cord-355413-ls2nud43	21	1	To	to	TO
cord-355413-ls2nud43	21	2	achieve	achieve	VB
cord-355413-ls2nud43	21	3	this	this	DT
cord-355413-ls2nud43	21	4	goal	goal	NN
cord-355413-ls2nud43	21	5	,	,	,
cord-355413-ls2nud43	21	6	a	a	DT
cord-355413-ls2nud43	21	7	generation	generation	NN
cord-355413-ls2nud43	21	8	of	of	IN
cord-355413-ls2nud43	21	9	genetic	genetic	JJ
cord-355413-ls2nud43	21	10	models	model	NNS
cord-355413-ls2nud43	21	11	with	with	IN
cord-355413-ls2nud43	21	12	selective	selective	JJ
cord-355413-ls2nud43	21	13	NK	NK	NNP
cord-355413-ls2nud43	21	14	cell	cell	NN
cord-355413-ls2nud43	21	15	deficiency	deficiency	NN
cord-355413-ls2nud43	21	16	,	,	,
cord-355413-ls2nud43	21	17	and	and	CC
cord-355413-ls2nud43	21	18	development	development	NN
cord-355413-ls2nud43	21	19	of	of	IN
cord-355413-ls2nud43	21	20	reagents	reagent	NNS
cord-355413-ls2nud43	21	21	(	(	-LRB-
cord-355413-ls2nud43	21	22	antibodies	antibody	NNS
cord-355413-ls2nud43	21	23	)	)	-RRB-
cord-355413-ls2nud43	21	24	for	for	IN
cord-355413-ls2nud43	21	25	visualizing	visualize	VBG
cord-355413-ls2nud43	21	26	subsets	subset	NNS
cord-355413-ls2nud43	21	27	of	of	IN
cord-355413-ls2nud43	21	28	NK	NK	NNP
cord-355413-ls2nud43	21	29	cells	cell	NNS
cord-355413-ls2nud43	21	30	in	in	IN
cord-355413-ls2nud43	21	31	situ	situ	NN
cord-355413-ls2nud43	21	32	will	will	MD
cord-355413-ls2nud43	21	33	be	be	VB
cord-355413-ls2nud43	21	34	necessary	necessary	JJ
cord-355413-ls2nud43	21	35	.	.	.
cord-355413-ls2nud43	22	1	cells	cell	NNS
cord-355413-ls2nud43	22	2	in	in	IN
cord-355413-ls2nud43	22	3	human	human	JJ
cord-355413-ls2nud43	22	4	CNS	CNS	NNP
cord-355413-ls2nud43	22	5	tissues	tissue	NNS
cord-355413-ls2nud43	22	6	is	be	VBZ
cord-355413-ls2nud43	22	7	still	still	RB
cord-355413-ls2nud43	22	8	lacking	lack	VBG
cord-355413-ls2nud43	22	9	.	.	.
cord-355413-ls2nud43	23	1	This	this	DT
cord-355413-ls2nud43	23	2	is	be	VBZ
cord-355413-ls2nud43	23	3	partly	partly	RB
cord-355413-ls2nud43	23	4	because	because	IN
cord-355413-ls2nud43	23	5	of	of	IN
cord-355413-ls2nud43	23	6	the	the	DT
cord-355413-ls2nud43	23	7	lack	lack	NN
cord-355413-ls2nud43	23	8	of	of	IN
cord-355413-ls2nud43	23	9	suitable	suitable	JJ
cord-355413-ls2nud43	23	10	antibodies	antibody	NNS
cord-355413-ls2nud43	23	11	for	for	IN
cord-355413-ls2nud43	23	12	staining	stain	VBG
cord-355413-ls2nud43	23	13	human	human	JJ
cord-355413-ls2nud43	23	14	NK	NK	NNP
cord-355413-ls2nud43	23	15	cells	cell	NNS
cord-355413-ls2nud43	23	16	in	in	IN
cord-355413-ls2nud43	23	17	situ	situ	NN
cord-355413-ls2nud43	23	18	(	(	-LRB-
cord-355413-ls2nud43	23	19	see	see	VB
cord-355413-ls2nud43	23	20	Chapter	Chapter	NNP
cord-355413-ls2nud43	23	21	31	31	CD
cord-355413-ls2nud43	23	22	)	)	-RRB-
cord-355413-ls2nud43	23	23	.	.	.
cord-355413-ls2nud43	24	1	Visualization	visualization	NN
cord-355413-ls2nud43	24	2	of	of	IN
cord-355413-ls2nud43	24	3	NK	NK	NNP
cord-355413-ls2nud43	24	4	cells	cell	NNS
cord-355413-ls2nud43	24	5	in	in	IN
cord-355413-ls2nud43	24	6	mouse	mouse	NN
cord-355413-ls2nud43	24	7	brains	brain	NNS
cord-355413-ls2nud43	24	8	during	during	IN
cord-355413-ls2nud43	24	9	experimental	experimental	JJ
cord-355413-ls2nud43	24	10	autoimmune	autoimmune	JJ
cord-355413-ls2nud43	24	11	encephalomyelitis	encephalomyelitis	NN
cord-355413-ls2nud43	24	12	(	(	-LRB-
cord-355413-ls2nud43	24	13	EAE	EAE	NNP
cord-355413-ls2nud43	24	14	)	)	-RRB-
cord-355413-ls2nud43	24	15	was	be	VBD
cord-355413-ls2nud43	24	16	achieved	achieve	VBN
cord-355413-ls2nud43	24	17	using	use	VBG
cord-355413-ls2nud43	25	1	anti	anti	JJ
cord-355413-ls2nud43	25	2	-	-	JJ
cord-355413-ls2nud43	25	3	NK1.1	nk1.1	JJ
cord-355413-ls2nud43	25	4	mAb	mAb	NNS
cord-355413-ls2nud43	25	5	(	(	-LRB-
cord-355413-ls2nud43	25	6	PK136	pk136	NN
cord-355413-ls2nud43	25	7	)	)	-RRB-
cord-355413-ls2nud43	25	8	(	(	-LRB-
cord-355413-ls2nud43	25	9	Hammarberg	Hammarberg	NNP
cord-355413-ls2nud43	25	10	et	et	NNP
cord-355413-ls2nud43	25	11	al	al	NNP
cord-355413-ls2nud43	25	12	.	.	NNP
cord-355413-ls2nud43	25	13	,	,	,
cord-355413-ls2nud43	25	14	2000	2000	CD
cord-355413-ls2nud43	25	15	)	)	-RRB-
cord-355413-ls2nud43	25	16	.	.	.
cord-355413-ls2nud43	26	1	Antibodies	antibody	NNS
cord-355413-ls2nud43	26	2	such	such	JJ
cord-355413-ls2nud43	26	3	as	as	IN
cord-355413-ls2nud43	26	4	Ly49	Ly49	NNP
cord-355413-ls2nud43	26	5	have	have	VBP
cord-355413-ls2nud43	26	6	been	be	VBN
cord-355413-ls2nud43	26	7	successfully	successfully	RB
cord-355413-ls2nud43	26	8	used	use	VBN
cord-355413-ls2nud43	26	9	for	for	IN
cord-355413-ls2nud43	26	10	staining	stain	VBG
cord-355413-ls2nud43	26	11	NK	NK	NNP
cord-355413-ls2nud43	26	12	cells	cell	NNS
cord-355413-ls2nud43	26	13	in	in	IN
cord-355413-ls2nud43	26	14	lymphoid	lymphoid	JJ
cord-355413-ls2nud43	26	15	organs	organ	NNS
cord-355413-ls2nud43	26	16	(	(	-LRB-
cord-355413-ls2nud43	26	17	O'Leary	O'Leary	NNP
cord-355413-ls2nud43	26	18	et	et	NNP
cord-355413-ls2nud43	26	19	al	al	NNP
cord-355413-ls2nud43	26	20	.	.	NNP
cord-355413-ls2nud43	26	21	,	,	,
cord-355413-ls2nud43	26	22	2006	2006	CD
cord-355413-ls2nud43	26	23	)	)	-RRB-
cord-355413-ls2nud43	26	24	.	.	.
cord-355413-ls2nud43	27	1	Suitability	suitability	NN
cord-355413-ls2nud43	27	2	of	of	IN
cord-355413-ls2nud43	27	3	these	these	DT
cord-355413-ls2nud43	27	4	antibodies	antibody	NNS
cord-355413-ls2nud43	27	5	for	for	IN
cord-355413-ls2nud43	27	6	staining	stain	VBG
cord-355413-ls2nud43	27	7	CNS	CNS	NNP
cord-355413-ls2nud43	27	8	NK	NK	NNP
cord-355413-ls2nud43	27	9	cells	cell	NNS
cord-355413-ls2nud43	27	10	needs	need	VBZ
cord-355413-ls2nud43	27	11	to	to	TO
cord-355413-ls2nud43	27	12	be	be	VB
cord-355413-ls2nud43	27	13	verified	verify	VBN
cord-355413-ls2nud43	27	14	in	in	IN
cord-355413-ls2nud43	27	15	additional	additional	JJ
cord-355413-ls2nud43	27	16	studies	study	NNS
cord-355413-ls2nud43	27	17	.	.	.
cord-355413-ls2nud43	28	1	Although	although	IN
cord-355413-ls2nud43	28	2	direct	direct	JJ
cord-355413-ls2nud43	28	3	visualization	visualization	NN
cord-355413-ls2nud43	28	4	of	of	IN
cord-355413-ls2nud43	28	5	NK	NK	NNP
cord-355413-ls2nud43	28	6	cells	cell	NNS
cord-355413-ls2nud43	28	7	in	in	IN
cord-355413-ls2nud43	28	8	CNS	CNS	NNP
cord-355413-ls2nud43	28	9	tissues	tissue	NNS
cord-355413-ls2nud43	28	10	is	be	VBZ
cord-355413-ls2nud43	28	11	technically	technically	RB
cord-355413-ls2nud43	28	12	challenging	challenging	JJ
cord-355413-ls2nud43	28	13	,	,	,
cord-355413-ls2nud43	28	14	there	there	EX
cord-355413-ls2nud43	28	15	is	be	VBZ
cord-355413-ls2nud43	28	16	little	little	JJ
cord-355413-ls2nud43	28	17	doubt	doubt	NN
cord-355413-ls2nud43	28	18	that	that	IN
cord-355413-ls2nud43	28	19	NK	NK	NNP
cord-355413-ls2nud43	28	20	cells	cell	NNS
cord-355413-ls2nud43	28	21	,	,	,
cord-355413-ls2nud43	28	22	as	as	IN
cord-355413-ls2nud43	28	23	with	with	IN
cord-355413-ls2nud43	28	24	other	other	JJ
cord-355413-ls2nud43	28	25	types	type	NNS
cord-355413-ls2nud43	28	26	of	of	IN
cord-355413-ls2nud43	28	27	lymphocytes	lymphocyte	NNS
cord-355413-ls2nud43	28	28	,	,	,
cord-355413-ls2nud43	28	29	enter	enter	VB
cord-355413-ls2nud43	28	30	the	the	DT
cord-355413-ls2nud43	28	31	CNS	CNS	NNP
cord-355413-ls2nud43	28	32	during	during	IN
cord-355413-ls2nud43	28	33	inflammatory	inflammatory	JJ
cord-355413-ls2nud43	28	34	processes	process	NNS
cord-355413-ls2nud43	28	35	.	.	.
cord-355413-ls2nud43	29	1	In	in	IN
cord-355413-ls2nud43	29	2	fact	fact	NN
cord-355413-ls2nud43	29	3	,	,	,
cord-355413-ls2nud43	29	4	it	-PRON-	PRP
cord-355413-ls2nud43	29	5	has	have	VBZ
cord-355413-ls2nud43	29	6	been	be	VBN
cord-355413-ls2nud43	29	7	reported	report	VBN
cord-355413-ls2nud43	29	8	that	that	IN
cord-355413-ls2nud43	29	9	NK	NK	NNP
cord-355413-ls2nud43	29	10	cells	cell	NNS
cord-355413-ls2nud43	29	11	are	be	VBP
cord-355413-ls2nud43	29	12	among	among	IN
cord-355413-ls2nud43	29	13	the	the	DT
cord-355413-ls2nud43	29	14	earliest	early	JJS
cord-355413-ls2nud43	29	15	recruited	recruit	VBN
cord-355413-ls2nud43	29	16	cells	cell	NNS
cord-355413-ls2nud43	29	17	during	during	IN
cord-355413-ls2nud43	29	18	adoptive	adoptive	JJ
cord-355413-ls2nud43	29	19	transfer	transfer	NN
cord-355413-ls2nud43	29	20	EAE	EAE	NNP
cord-355413-ls2nud43	29	21	(	(	-LRB-
cord-355413-ls2nud43	29	22	Kerfoot	Kerfoot	NNP
cord-355413-ls2nud43	29	23	and	and	CC
cord-355413-ls2nud43	29	24	Kubes	Kubes	NNP
cord-355413-ls2nud43	29	25	,	,	,
cord-355413-ls2nud43	29	26	2002	2002	CD
cord-355413-ls2nud43	29	27	;	;	:
cord-355413-ls2nud43	29	28	Wekerle	Wekerle	NNP
cord-355413-ls2nud43	29	29	and	and	CC
cord-355413-ls2nud43	29	30	Fierz	Fierz	NNP
cord-355413-ls2nud43	29	31	,	,	,
cord-355413-ls2nud43	29	32	1985	1985	CD
cord-355413-ls2nud43	29	33	)	)	-RRB-
cord-355413-ls2nud43	29	34	.	.	.
cord-355413-ls2nud43	30	1	Chemokine	chemokine	JJ
cord-355413-ls2nud43	30	2	receptors	receptor	NNS
cord-355413-ls2nud43	30	3	such	such	JJ
cord-355413-ls2nud43	30	4	as	as	IN
cord-355413-ls2nud43	30	5	CCR2	CCR2	NNP
cord-355413-ls2nud43	30	6	,	,	,
cord-355413-ls2nud43	30	7	CCR5	CCR5	NNP
cord-355413-ls2nud43	30	8	,	,	,
cord-355413-ls2nud43	30	9	CXCR3	cxcr3	XX
cord-355413-ls2nud43	30	10	,	,	,
cord-355413-ls2nud43	30	11	CX3CR1	CX3CR1	NNP
cord-355413-ls2nud43	30	12	as	as	RB
cord-355413-ls2nud43	30	13	well	well	RB
cord-355413-ls2nud43	30	14	as	as	IN
cord-355413-ls2nud43	30	15	lysophospholipid	lysophospholipid	NNP
cord-355413-ls2nud43	30	16	sphingosine	sphingosine	NNP
cord-355413-ls2nud43	30	17	1-phosphate	1-phosphate	NNP
cord-355413-ls2nud43	30	18	(	(	-LRB-
cord-355413-ls2nud43	30	19	S1P	s1p	NN
cord-355413-ls2nud43	30	20	)	)	-RRB-
cord-355413-ls2nud43	30	21	are	be	VBP
cord-355413-ls2nud43	30	22	involved	involve	VBN
cord-355413-ls2nud43	30	23	in	in	IN
cord-355413-ls2nud43	30	24	the	the	DT
cord-355413-ls2nud43	30	25	rapid	rapid	JJ
cord-355413-ls2nud43	30	26	NK	nk	NN
cord-355413-ls2nud43	30	27	-	-	HYPH
cord-355413-ls2nud43	30	28	cell	cell	NN
cord-355413-ls2nud43	30	29	mobilization	mobilization	NN
cord-355413-ls2nud43	30	30	that	that	WDT
cord-355413-ls2nud43	30	31	occurs	occur	VBZ
cord-355413-ls2nud43	30	32	in	in	IN
cord-355413-ls2nud43	30	33	inflammatory	inflammatory	JJ
cord-355413-ls2nud43	30	34	conditions	condition	NNS
cord-355413-ls2nud43	30	35	(	(	-LRB-
cord-355413-ls2nud43	30	36	Ajuebor	Ajuebor	NNP
cord-355413-ls2nud43	30	37	et	et	NNP
cord-355413-ls2nud43	30	38	al	al	NNP
cord-355413-ls2nud43	30	39	.	.	NNP
cord-355413-ls2nud43	30	40	,	,	,
cord-355413-ls2nud43	30	41	2007	2007	CD
cord-355413-ls2nud43	31	1	;	;	:
cord-355413-ls2nud43	31	2	Hokeness	Hokeness	NNP
cord-355413-ls2nud43	31	3	et	et	NNP
cord-355413-ls2nud43	31	4	al	al	NNP
cord-355413-ls2nud43	31	5	.	.	NNP
cord-355413-ls2nud43	31	6	,	,	,
cord-355413-ls2nud43	31	7	2005	2005	CD
cord-355413-ls2nud43	31	8	;	;	:
cord-355413-ls2nud43	31	9	Huang	Huang	NNP
cord-355413-ls2nud43	31	10	et	et	NNP
cord-355413-ls2nud43	31	11	al	al	NNP
cord-355413-ls2nud43	31	12	.	.	NNP
cord-355413-ls2nud43	31	13	,	,	,
cord-355413-ls2nud43	31	14	2006	2006	CD
cord-355413-ls2nud43	32	1	;	;	:
cord-355413-ls2nud43	32	2	Inngjerdingen	Inngjerdingen	NNP
cord-355413-ls2nud43	32	3	et	et	NNP
cord-355413-ls2nud43	32	4	al	al	NNP
cord-355413-ls2nud43	32	5	.	.	NNP
cord-355413-ls2nud43	32	6	,	,	,
cord-355413-ls2nud43	32	7	2001	2001	CD
cord-355413-ls2nud43	32	8	;	;	:
cord-355413-ls2nud43	32	9	Jiang	Jiang	NNP
cord-355413-ls2nud43	32	10	et	et	FW
cord-355413-ls2nud43	32	11	al	al	NNP
cord-355413-ls2nud43	32	12	.	.	NNP
cord-355413-ls2nud43	32	13	,	,	,
cord-355413-ls2nud43	32	14	2004	2004	CD
cord-355413-ls2nud43	33	1	;	;	:
cord-355413-ls2nud43	33	2	Khan	Khan	NNP
cord-355413-ls2nud43	33	3	et	et	NNP
cord-355413-ls2nud43	33	4	al	al	NNP
cord-355413-ls2nud43	33	5	.	.	NNP
cord-355413-ls2nud43	33	6	,	,	,
cord-355413-ls2nud43	33	7	2006	2006	CD
cord-355413-ls2nud43	33	8	;	;	:
cord-355413-ls2nud43	33	9	Kveberg	Kveberg	NNP
cord-355413-ls2nud43	33	10	et	et	NNP
cord-355413-ls2nud43	33	11	al	al	NNP
cord-355413-ls2nud43	33	12	.	.	NNP
cord-355413-ls2nud43	33	13	,	,	,
cord-355413-ls2nud43	33	14	2002	2002	CD
cord-355413-ls2nud43	33	15	;	;	:
cord-355413-ls2nud43	33	16	Lavergne	Lavergne	NNP
cord-355413-ls2nud43	33	17	et	et	NNP
cord-355413-ls2nud43	33	18	al	al	NNP
cord-355413-ls2nud43	33	19	.	.	NNP
cord-355413-ls2nud43	33	20	,	,	,
cord-355413-ls2nud43	33	21	2003	2003	CD
cord-355413-ls2nud43	33	22	;	;	:
cord-355413-ls2nud43	33	23	Martin	Martin	NNP
cord-355413-ls2nud43	33	24	-	-	HYPH
cord-355413-ls2nud43	33	25	Fontecha	Fontecha	NNP
cord-355413-ls2nud43	33	26	et	et	NNP
cord-355413-ls2nud43	33	27	al	al	NNP
cord-355413-ls2nud43	33	28	.	.	NNP
cord-355413-ls2nud43	33	29	,	,	,
cord-355413-ls2nud43	33	30	2004	2004	CD
cord-355413-ls2nud43	34	1	;	;	:
cord-355413-ls2nud43	34	2	Thapa	Thapa	NNP
cord-355413-ls2nud43	34	3	et	et	NNP
cord-355413-ls2nud43	34	4	al	al	NNP
cord-355413-ls2nud43	34	5	.	.	NNP
cord-355413-ls2nud43	34	6	,	,	,
cord-355413-ls2nud43	34	7	2007	2007	CD
cord-355413-ls2nud43	34	8	;	;	:
cord-355413-ls2nud43	34	9	Wald	Wald	NNP
cord-355413-ls2nud43	34	10	et	et	NNP
cord-355413-ls2nud43	34	11	al	al	NNP
cord-355413-ls2nud43	34	12	.	.	NNP
cord-355413-ls2nud43	34	13	,	,	,
cord-355413-ls2nud43	34	14	2006	2006	CD
cord-355413-ls2nud43	35	1	;	;	:
cord-355413-ls2nud43	35	2	Walzer	Walzer	NNP
cord-355413-ls2nud43	35	3	et	et	NNP
cord-355413-ls2nud43	35	4	al	al	NNP
cord-355413-ls2nud43	35	5	.	.	NNP
cord-355413-ls2nud43	35	6	,	,	,
cord-355413-ls2nud43	35	7	2007	2007	CD
cord-355413-ls2nud43	36	1	;	;	:
cord-355413-ls2nud43	36	2	Yu	Yu	NNP
cord-355413-ls2nud43	36	3	et	et	NNP
cord-355413-ls2nud43	36	4	al	al	NNP
cord-355413-ls2nud43	36	5	.	.	NNP
cord-355413-ls2nud43	36	6	,	,	,
cord-355413-ls2nud43	36	7	2007	2007	CD
cord-355413-ls2nud43	36	8	)	)	-RRB-
cord-355413-ls2nud43	36	9	,	,	,
cord-355413-ls2nud43	36	10	and	and	CC
cord-355413-ls2nud43	36	11	several	several	JJ
cord-355413-ls2nud43	36	12	of	of	IN
cord-355413-ls2nud43	36	13	these	these	DT
cord-355413-ls2nud43	36	14	chemokine	chemokine	NN
cord-355413-ls2nud43	36	15	receptors	receptor	NNS
cord-355413-ls2nud43	36	16	(	(	-LRB-
cord-355413-ls2nud43	36	17	CCR5	CCR5	NNP
cord-355413-ls2nud43	36	18	,	,	,
cord-355413-ls2nud43	36	19	CX3CR1	CX3CR1	NNP
cord-355413-ls2nud43	36	20	)	)	-RRB-
cord-355413-ls2nud43	36	21	are	be	VBP
cord-355413-ls2nud43	36	22	directly	directly	RB
cord-355413-ls2nud43	36	23	involved	involve	VBN
cord-355413-ls2nud43	36	24	in	in	IN
cord-355413-ls2nud43	36	25	NK	NK	NNP
cord-355413-ls2nud43	36	26	cell	cell	NN
cord-355413-ls2nud43	36	27	homing	homing	NN
cord-355413-ls2nud43	36	28	to	to	IN
cord-355413-ls2nud43	36	29	the	the	DT
cord-355413-ls2nud43	36	30	CNS	CNS	NNP
cord-355413-ls2nud43	37	1	(	(	-LRB-
cord-355413-ls2nud43	37	2	Huang	Huang	NNP
cord-355413-ls2nud43	37	3	et	et	NNP
cord-355413-ls2nud43	37	4	al	al	NNP
cord-355413-ls2nud43	37	5	.	.	NNP
cord-355413-ls2nud43	37	6	,	,	,
cord-355413-ls2nud43	37	7	2006	2006	CD
cord-355413-ls2nud43	37	8	;	;	:
cord-355413-ls2nud43	37	9	Martin	Martin	NNP
cord-355413-ls2nud43	37	10	-	-	HYPH
cord-355413-ls2nud43	37	11	Fontecha	Fontecha	NNP
cord-355413-ls2nud43	37	12	et	et	NNP
cord-355413-ls2nud43	37	13	al	al	NNP
cord-355413-ls2nud43	37	14	.	.	NNP
cord-355413-ls2nud43	37	15	,	,	,
cord-355413-ls2nud43	37	16	2004	2004	CD
cord-355413-ls2nud43	38	1	;	;	:
cord-355413-ls2nud43	38	2	Thapa	Thapa	NNP
cord-355413-ls2nud43	38	3	et	et	NNP
cord-355413-ls2nud43	38	4	al	al	NNP
cord-355413-ls2nud43	38	5	.	.	NNP
cord-355413-ls2nud43	38	6	,	,	,
cord-355413-ls2nud43	38	7	2007	2007	CD
cord-355413-ls2nud43	38	8	)	)	-RRB-
cord-355413-ls2nud43	38	9	.	.	.
cord-355413-ls2nud43	39	1	The	the	DT
cord-355413-ls2nud43	39	2	biological	biological	JJ
cord-355413-ls2nud43	39	3	implication	implication	NN
cord-355413-ls2nud43	39	4	of	of	IN
cord-355413-ls2nud43	39	5	chemokine	chemokine	NN
cord-355413-ls2nud43	39	6	-	-	HYPH
cord-355413-ls2nud43	39	7	guided	guide	VBN
cord-355413-ls2nud43	39	8	homing	homing	NN
cord-355413-ls2nud43	39	9	of	of	IN
cord-355413-ls2nud43	39	10	NK	NK	NNP
cord-355413-ls2nud43	39	11	cells	cell	NNS
cord-355413-ls2nud43	39	12	during	during	IN
cord-355413-ls2nud43	39	13	CNS	CNS	NNP
cord-355413-ls2nud43	39	14	inflammation	inflammation	NN
cord-355413-ls2nud43	39	15	is	be	VBZ
cord-355413-ls2nud43	39	16	discussed	discuss	VBN
cord-355413-ls2nud43	39	17	in	in	IN
cord-355413-ls2nud43	39	18	greater	great	JJR
cord-355413-ls2nud43	39	19	detail	detail	NN
cord-355413-ls2nud43	39	20	in	in	IN
cord-355413-ls2nud43	39	21	the	the	DT
cord-355413-ls2nud43	39	22	following	following	JJ
cord-355413-ls2nud43	39	23	section	section	NN
cord-355413-ls2nud43	39	24	.	.	.
cord-355413-ls2nud43	40	1	The	the	DT
cord-355413-ls2nud43	40	2	ability	ability	NN
cord-355413-ls2nud43	40	3	of	of	IN
cord-355413-ls2nud43	40	4	NK	NK	NNP
cord-355413-ls2nud43	40	5	cells	cell	NNS
cord-355413-ls2nud43	40	6	to	to	TO
cord-355413-ls2nud43	40	7	kill	kill	VB
cord-355413-ls2nud43	40	8	various	various	JJ
cord-355413-ls2nud43	40	9	transformed	transform	VBN
cord-355413-ls2nud43	40	10	and	and	CC
cord-355413-ls2nud43	40	11	virus	virus	NN
cord-355413-ls2nud43	40	12	-	-	HYPH
cord-355413-ls2nud43	40	13	infected	infect	VBN
cord-355413-ls2nud43	40	14	cells	cell	NNS
cord-355413-ls2nud43	40	15	raises	raise	VBZ
cord-355413-ls2nud43	40	16	an	an	DT
cord-355413-ls2nud43	40	17	important	important	JJ
cord-355413-ls2nud43	40	18	question	question	NN
cord-355413-ls2nud43	40	19	whether	whether	IN
cord-355413-ls2nud43	40	20	direct	direct	JJ
cord-355413-ls2nud43	40	21	NK	NK	NNP
cord-355413-ls2nud43	40	22	cell	cell	NN
cord-355413-ls2nud43	40	23	cytolytic	cytolytic	JJ
cord-355413-ls2nud43	40	24	effects	effect	NNS
cord-355413-ls2nud43	40	25	contribute	contribute	VBP
cord-355413-ls2nud43	40	26	to	to	IN
cord-355413-ls2nud43	40	27	the	the	DT
cord-355413-ls2nud43	40	28	pathogenesis	pathogenesis	NN
cord-355413-ls2nud43	40	29	of	of	IN
cord-355413-ls2nud43	40	30	inflammatory	inflammatory	JJ
cord-355413-ls2nud43	40	31	,	,	,
cord-355413-ls2nud43	40	32	degenerative	degenerative	JJ
cord-355413-ls2nud43	40	33	and	and	CC
cord-355413-ls2nud43	40	34	autoimmune	autoimmune	JJ
cord-355413-ls2nud43	40	35	disorders	disorder	NNS
cord-355413-ls2nud43	40	36	of	of	IN
cord-355413-ls2nud43	40	37	the	the	DT
cord-355413-ls2nud43	40	38	nervous	nervous	JJ
cord-355413-ls2nud43	40	39	system	system	NN
cord-355413-ls2nud43	40	40	.	.	.
cord-355413-ls2nud43	41	1	Neurodegenerative	neurodegenerative	JJ
cord-355413-ls2nud43	41	2	diseases	disease	NNS
cord-355413-ls2nud43	41	3	such	such	JJ
cord-355413-ls2nud43	41	4	as	as	IN
cord-355413-ls2nud43	41	5	Parkinson	Parkinson	NNP
cord-355413-ls2nud43	41	6	's	's	POS
cord-355413-ls2nud43	41	7	disease	disease	NN
cord-355413-ls2nud43	41	8	and	and	CC
cord-355413-ls2nud43	41	9	Alzheimer	Alzheimer	NNP
cord-355413-ls2nud43	41	10	's	's	POS
cord-355413-ls2nud43	41	11	disease	disease	NN
cord-355413-ls2nud43	41	12	are	be	VBP
cord-355413-ls2nud43	41	13	characterized	characterize	VBN
cord-355413-ls2nud43	41	14	by	by	IN
cord-355413-ls2nud43	41	15	the	the	DT
cord-355413-ls2nud43	41	16	death	death	NN
cord-355413-ls2nud43	41	17	of	of	IN
cord-355413-ls2nud43	41	18	neurons	neuron	NNS
cord-355413-ls2nud43	41	19	in	in	IN
cord-355413-ls2nud43	41	20	distinct	distinct	JJ
cord-355413-ls2nud43	41	21	functional	functional	JJ
cord-355413-ls2nud43	41	22	neuron	neuron	NN
cord-355413-ls2nud43	41	23	-	-	HYPH
cord-355413-ls2nud43	41	24	anatomic	anatomic	JJ
cord-355413-ls2nud43	41	25	systems	system	NNS
cord-355413-ls2nud43	41	26	.	.	.
cord-355413-ls2nud43	42	1	Multiple	multiple	JJ
cord-355413-ls2nud43	42	2	sclerosis	sclerosis	NN
cord-355413-ls2nud43	42	3	(	(	-LRB-
cord-355413-ls2nud43	42	4	MS	MS	NNP
cord-355413-ls2nud43	42	5	)	)	-RRB-
cord-355413-ls2nud43	42	6	,	,	,
cord-355413-ls2nud43	42	7	on	on	IN
cord-355413-ls2nud43	42	8	the	the	DT
cord-355413-ls2nud43	42	9	other	other	JJ
cord-355413-ls2nud43	42	10	hand	hand	NN
cord-355413-ls2nud43	42	11	,	,	,
cord-355413-ls2nud43	42	12	is	be	VBZ
cord-355413-ls2nud43	42	13	characterized	characterize	VBN
cord-355413-ls2nud43	42	14	by	by	IN
cord-355413-ls2nud43	42	15	inflammation	inflammation	NN
cord-355413-ls2nud43	42	16	and	and	CC
cord-355413-ls2nud43	42	17	demyelination	demyelination	NN
cord-355413-ls2nud43	42	18	within	within	IN
cord-355413-ls2nud43	42	19	the	the	DT
cord-355413-ls2nud43	42	20	spinal	spinal	JJ
cord-355413-ls2nud43	42	21	cord	cord	NN
cord-355413-ls2nud43	42	22	and	and	CC
cord-355413-ls2nud43	42	23	brain	brain	NN
cord-355413-ls2nud43	42	24	,	,	,
cord-355413-ls2nud43	42	25	and	and	CC
cord-355413-ls2nud43	42	26	axonal	axonal	JJ
cord-355413-ls2nud43	42	27	damage	damage	NN
cord-355413-ls2nud43	42	28	and	and	CC
cord-355413-ls2nud43	42	29	brain	brain	NN
cord-355413-ls2nud43	42	30	atrophy	atrophy	NN
cord-355413-ls2nud43	42	31	also	also	RB
cord-355413-ls2nud43	42	32	occur	occur	VBP
cord-355413-ls2nud43	42	33	during	during	IN
cord-355413-ls2nud43	42	34	the	the	DT
cord-355413-ls2nud43	42	35	course	course	NN
cord-355413-ls2nud43	42	36	of	of	IN
cord-355413-ls2nud43	42	37	disease	disease	NN
cord-355413-ls2nud43	42	38	.	.	.
cord-355413-ls2nud43	43	1	The	the	DT
cord-355413-ls2nud43	43	2	peripheral	peripheral	JJ
cord-355413-ls2nud43	43	3	form	form	NN
cord-355413-ls2nud43	43	4	of	of	IN
cord-355413-ls2nud43	43	5	MS	MS	NNP
cord-355413-ls2nud43	43	6	is	be	VBZ
cord-355413-ls2nud43	43	7	Guillain	Guillain	NNP
cord-355413-ls2nud43	43	8	-	-	HYPH
cord-355413-ls2nud43	43	9	Barré	Barré	NNP
cord-355413-ls2nud43	43	10	syndrome	syndrome	NN
cord-355413-ls2nud43	43	11	,	,	,
cord-355413-ls2nud43	43	12	which	which	WDT
cord-355413-ls2nud43	43	13	is	be	VBZ
cord-355413-ls2nud43	43	14	also	also	RB
cord-355413-ls2nud43	43	15	characterized	characterize	VBN
cord-355413-ls2nud43	43	16	by	by	IN
cord-355413-ls2nud43	43	17	demyelination	demyelination	NN
cord-355413-ls2nud43	43	18	and	and	CC
cord-355413-ls2nud43	43	19	cellular	cellular	JJ
cord-355413-ls2nud43	43	20	infiltrates	infiltrate	NNS
cord-355413-ls2nud43	43	21	of	of	IN
cord-355413-ls2nud43	43	22	the	the	DT
cord-355413-ls2nud43	43	23	peripheral	peripheral	JJ
cord-355413-ls2nud43	43	24	nervous	nervous	JJ
cord-355413-ls2nud43	43	25	system	system	NN
cord-355413-ls2nud43	43	26	.	.	.
cord-355413-ls2nud43	44	1	Some	some	DT
cord-355413-ls2nud43	44	2	of	of	IN
cord-355413-ls2nud43	44	3	these	these	DT
cord-355413-ls2nud43	44	4	diseases	disease	NNS
cord-355413-ls2nud43	44	5	involve	involve	VBP
cord-355413-ls2nud43	44	6	immunologic	immunologic	JJ
cord-355413-ls2nud43	44	7	components	component	NNS
cord-355413-ls2nud43	44	8	or	or	CC
cord-355413-ls2nud43	44	9	reactions	reaction	NNS
cord-355413-ls2nud43	44	10	,	,	,
cord-355413-ls2nud43	44	11	and	and	CC
cord-355413-ls2nud43	44	12	some	some	DT
cord-355413-ls2nud43	44	13	have	have	VBP
cord-355413-ls2nud43	44	14	been	be	VBN
cord-355413-ls2nud43	44	15	characterized	characterize	VBN
cord-355413-ls2nud43	44	16	extensively	extensively	RB
cord-355413-ls2nud43	44	17	in	in	IN
cord-355413-ls2nud43	44	18	the	the	DT
cord-355413-ls2nud43	44	19	different	different	JJ
cord-355413-ls2nud43	44	20	systems	system	NNS
cord-355413-ls2nud43	44	21	.	.	.
cord-355413-ls2nud43	45	1	Autoreactive	Autoreactive	NNP
cord-355413-ls2nud43	45	2	T	t	NN
cord-355413-ls2nud43	45	3	cells	cell	NNS
cord-355413-ls2nud43	45	4	and	and	CC
cord-355413-ls2nud43	45	5	adaptive	adaptive	JJ
cord-355413-ls2nud43	45	6	immune	immune	JJ
cord-355413-ls2nud43	45	7	system	system	NN
cord-355413-ls2nud43	45	8	components	component	NNS
cord-355413-ls2nud43	45	9	in	in	IN
cord-355413-ls2nud43	45	10	the	the	DT
cord-355413-ls2nud43	45	11	pathogenesis	pathogenesis	NN
cord-355413-ls2nud43	45	12	in	in	IN
cord-355413-ls2nud43	45	13	some	some	DT
cord-355413-ls2nud43	45	14	of	of	IN
cord-355413-ls2nud43	45	15	these	these	DT
cord-355413-ls2nud43	45	16	disorders	disorder	NNS
cord-355413-ls2nud43	45	17	are	be	VBP
cord-355413-ls2nud43	45	18	well	well	RB
cord-355413-ls2nud43	45	19	characterized	characterize	VBN
cord-355413-ls2nud43	45	20	.	.	.
cord-355413-ls2nud43	46	1	As	as	IN
cord-355413-ls2nud43	46	2	discussed	discuss	VBN
cord-355413-ls2nud43	46	3	here	here	RB
cord-355413-ls2nud43	46	4	,	,	,
cord-355413-ls2nud43	46	5	evidence	evidence	NN
cord-355413-ls2nud43	46	6	for	for	IN
cord-355413-ls2nud43	46	7	direct	direct	JJ
cord-355413-ls2nud43	46	8	NK	NK	NNP
cord-355413-ls2nud43	46	9	cell	cell	NN
cord-355413-ls2nud43	46	10	cytolytic	cytolytic	JJ
cord-355413-ls2nud43	46	11	effects	effect	NNS
cord-355413-ls2nud43	46	12	is	be	VBZ
cord-355413-ls2nud43	46	13	emerging	emerge	VBG
cord-355413-ls2nud43	46	14	.	.	.
cord-355413-ls2nud43	47	1	Although	although	IN
cord-355413-ls2nud43	47	2	the	the	DT
cord-355413-ls2nud43	47	3	in	in	IN
cord-355413-ls2nud43	47	4	vivo	vivo	NN
cord-355413-ls2nud43	47	5	relevance	relevance	NN
cord-355413-ls2nud43	47	6	of	of	IN
cord-355413-ls2nud43	47	7	a	a	DT
cord-355413-ls2nud43	47	8	great	great	JJ
cord-355413-ls2nud43	47	9	proportion	proportion	NN
cord-355413-ls2nud43	47	10	of	of	IN
cord-355413-ls2nud43	47	11	these	these	DT
cord-355413-ls2nud43	47	12	studies	study	NNS
cord-355413-ls2nud43	47	13	needs	need	VBZ
cord-355413-ls2nud43	47	14	to	to	TO
cord-355413-ls2nud43	47	15	be	be	VB
cord-355413-ls2nud43	47	16	validated	validate	VBN
cord-355413-ls2nud43	47	17	,	,	,
cord-355413-ls2nud43	47	18	the	the	DT
cord-355413-ls2nud43	47	19	current	current	JJ
cord-355413-ls2nud43	47	20	data	datum	NNS
cord-355413-ls2nud43	47	21	emphasize	emphasize	VBP
cord-355413-ls2nud43	47	22	the	the	DT
cord-355413-ls2nud43	47	23	importance	importance	NN
cord-355413-ls2nud43	47	24	of	of	IN
cord-355413-ls2nud43	47	25	NK	NK	NNP
cord-355413-ls2nud43	47	26	cells	cell	NNS
cord-355413-ls2nud43	47	27	either	either	CC
cord-355413-ls2nud43	47	28	in	in	IN
cord-355413-ls2nud43	47	29	direct	direct	JJ
cord-355413-ls2nud43	47	30	cytotoxic	cytotoxic	JJ
cord-355413-ls2nud43	47	31	effects	effect	NNS
cord-355413-ls2nud43	47	32	or	or	CC
cord-355413-ls2nud43	47	33	in	in	IN
cord-355413-ls2nud43	47	34	collaboration	collaboration	NN
cord-355413-ls2nud43	47	35	with	with	IN
cord-355413-ls2nud43	47	36	cells	cell	NNS
cord-355413-ls2nud43	47	37	from	from	IN
cord-355413-ls2nud43	47	38	both	both	DT
cord-355413-ls2nud43	47	39	innate	innate	JJ
cord-355413-ls2nud43	47	40	and	and	CC
cord-355413-ls2nud43	47	41	adaptive	adaptive	JJ
cord-355413-ls2nud43	47	42	immune	immune	JJ
cord-355413-ls2nud43	47	43	systems	system	NNS
cord-355413-ls2nud43	47	44	in	in	IN
cord-355413-ls2nud43	47	45	the	the	DT
cord-355413-ls2nud43	47	46	initiation	initiation	NN
cord-355413-ls2nud43	47	47	of	of	IN
cord-355413-ls2nud43	47	48	these	these	DT
cord-355413-ls2nud43	47	49	neurodegenerative	neurodegenerative	JJ
cord-355413-ls2nud43	47	50	and	and	CC
cord-355413-ls2nud43	47	51	inflammatory	inflammatory	JJ
cord-355413-ls2nud43	47	52	diseases	disease	NNS
cord-355413-ls2nud43	47	53	.	.	.
cord-355413-ls2nud43	48	1	The	the	DT
cord-355413-ls2nud43	48	2	NK	NK	NNP
cord-355413-ls2nud43	48	3	cell	cell	NN
cord-355413-ls2nud43	48	4	-	-	HYPH
cord-355413-ls2nud43	48	5	dependent	dependent	JJ
cord-355413-ls2nud43	48	6	death	death	NN
cord-355413-ls2nud43	48	7	of	of	IN
cord-355413-ls2nud43	48	8	sympathetic	sympathetic	JJ
cord-355413-ls2nud43	48	9	neurons	neuron	NNS
cord-355413-ls2nud43	48	10	resident	resident	JJ
cord-355413-ls2nud43	48	11	in	in	IN
cord-355413-ls2nud43	48	12	the	the	DT
cord-355413-ls2nud43	48	13	superior	superior	JJ
cord-355413-ls2nud43	48	14	cervical	cervical	JJ
cord-355413-ls2nud43	48	15	ganglia	ganglion	NNS
cord-355413-ls2nud43	48	16	of	of	IN
cord-355413-ls2nud43	48	17	rats	rat	NNS
cord-355413-ls2nud43	48	18	,	,	,
cord-355413-ls2nud43	48	19	observed	observe	VBD
cord-355413-ls2nud43	48	20	after	after	IN
cord-355413-ls2nud43	48	21	the	the	DT
cord-355413-ls2nud43	48	22	exposure	exposure	NN
cord-355413-ls2nud43	48	23	to	to	IN
cord-355413-ls2nud43	48	24	the	the	DT
cord-355413-ls2nud43	48	25	drug	drug	NN
cord-355413-ls2nud43	48	26	guanethidine	guanethidine	NN
cord-355413-ls2nud43	48	27	(	(	-LRB-
cord-355413-ls2nud43	48	28	Hickey	Hickey	NNP
cord-355413-ls2nud43	48	29	et	et	NNP
cord-355413-ls2nud43	48	30	al	al	NNP
cord-355413-ls2nud43	48	31	.	.	NNP
cord-355413-ls2nud43	48	32	,	,	,
cord-355413-ls2nud43	48	33	1992	1992	CD
cord-355413-ls2nud43	48	34	;	;	.
cord-355413-ls2nud43	49	1	Hougen	Hougen	NNP
cord-355413-ls2nud43	49	2	et	et	NNP
cord-355413-ls2nud43	49	3	al	al	NNP
cord-355413-ls2nud43	49	4	.	.	NNP
cord-355413-ls2nud43	49	5	,	,	,
cord-355413-ls2nud43	49	6	1992	1992	CD
cord-355413-ls2nud43	49	7	)	)	-RRB-
cord-355413-ls2nud43	49	8	,	,	,
cord-355413-ls2nud43	49	9	is	be	VBZ
cord-355413-ls2nud43	49	10	the	the	DT
cord-355413-ls2nud43	49	11	first	first	JJ
cord-355413-ls2nud43	49	12	in	in	IN
cord-355413-ls2nud43	49	13	vivo	vivo	NN
cord-355413-ls2nud43	49	14	disorder	disorder	NN
cord-355413-ls2nud43	49	15	of	of	IN
cord-355413-ls2nud43	49	16	the	the	DT
cord-355413-ls2nud43	49	17	nervous	nervous	JJ
cord-355413-ls2nud43	49	18	system	system	NN
cord-355413-ls2nud43	49	19	in	in	IN
cord-355413-ls2nud43	49	20	which	which	WDT
cord-355413-ls2nud43	49	21	NK	NK	NNP
cord-355413-ls2nud43	49	22	cells	cell	NNS
cord-355413-ls2nud43	49	23	appear	appear	VBP
cord-355413-ls2nud43	49	24	to	to	TO
cord-355413-ls2nud43	49	25	be	be	VB
cord-355413-ls2nud43	49	26	the	the	DT
cord-355413-ls2nud43	49	27	dominant	dominant	JJ
cord-355413-ls2nud43	49	28	effector	effector	NN
cord-355413-ls2nud43	49	29	cells	cell	NNS
cord-355413-ls2nud43	49	30	.	.	.
cord-355413-ls2nud43	50	1	The	the	DT
cord-355413-ls2nud43	50	2	pathogenic	pathogenic	JJ
cord-355413-ls2nud43	50	3	mechanism	mechanism	NN
cord-355413-ls2nud43	50	4	observed	observe	VBD
cord-355413-ls2nud43	50	5	appeared	appear	VBD
cord-355413-ls2nud43	50	6	to	to	TO
cord-355413-ls2nud43	50	7	represent	represent	VB
cord-355413-ls2nud43	50	8	a	a	DT
cord-355413-ls2nud43	50	9	novel	novel	JJ
cord-355413-ls2nud43	50	10	type	type	NN
cord-355413-ls2nud43	50	11	of	of	IN
cord-355413-ls2nud43	50	12	autoimmune	autoimmune	JJ
cord-355413-ls2nud43	50	13	reaction	reaction	NN
cord-355413-ls2nud43	50	14	:	:	:
cord-355413-ls2nud43	50	15	an	an	DT
cord-355413-ls2nud43	50	16	exogenously	exogenously	RB
cord-355413-ls2nud43	50	17	/	/	SYM
cord-355413-ls2nud43	50	18	chemically	chemically	RB
cord-355413-ls2nud43	50	19	induced	induce	VBN
cord-355413-ls2nud43	50	20	alteration	alteration	NN
cord-355413-ls2nud43	50	21	in	in	IN
cord-355413-ls2nud43	50	22	a	a	DT
cord-355413-ls2nud43	50	23	specific	specific	JJ
cord-355413-ls2nud43	50	24	subset	subset	NN
cord-355413-ls2nud43	50	25	of	of	IN
cord-355413-ls2nud43	50	26	cells	cell	NNS
cord-355413-ls2nud43	50	27	that	that	WDT
cord-355413-ls2nud43	50	28	was	be	VBD
cord-355413-ls2nud43	50	29	suggested	suggest	VBN
cord-355413-ls2nud43	50	30	to	to	TO
cord-355413-ls2nud43	50	31	target	target	VB
cord-355413-ls2nud43	50	32	them	-PRON-	PRP
cord-355413-ls2nud43	50	33	for	for	IN
cord-355413-ls2nud43	50	34	direct	direct	JJ
cord-355413-ls2nud43	50	35	NK	NK	NNP
cord-355413-ls2nud43	50	36	cell	cell	NN
cord-355413-ls2nud43	50	37	-	-	HYPH
cord-355413-ls2nud43	50	38	mediated	mediate	VBN
cord-355413-ls2nud43	50	39	killing	killing	NN
cord-355413-ls2nud43	50	40	.	.	.
cord-355413-ls2nud43	51	1	Interestingly	interestingly	RB
cord-355413-ls2nud43	51	2	,	,	,
cord-355413-ls2nud43	51	3	neuronal	neuronal	JJ
cord-355413-ls2nud43	51	4	cells	cell	NNS
cord-355413-ls2nud43	51	5	from	from	IN
cord-355413-ls2nud43	51	6	the	the	DT
cord-355413-ls2nud43	51	7	peripheral	peripheral	JJ
cord-355413-ls2nud43	51	8	system	system	NN
cord-355413-ls2nud43	51	9	and	and	CC
cord-355413-ls2nud43	51	10	the	the	DT
cord-355413-ls2nud43	51	11	CNS	CNS	NNP
cord-355413-ls2nud43	51	12	appear	appear	VBP
cord-355413-ls2nud43	51	13	to	to	TO
cord-355413-ls2nud43	51	14	have	have	VB
cord-355413-ls2nud43	51	15	different	different	JJ
cord-355413-ls2nud43	51	16	susceptibility	susceptibility	NN
cord-355413-ls2nud43	51	17	to	to	IN
cord-355413-ls2nud43	51	18	NK	NK	NNP
cord-355413-ls2nud43	51	19	cell	cell	NN
cord-355413-ls2nud43	51	20	killing	killing	NN
cord-355413-ls2nud43	51	21	.	.	.
cord-355413-ls2nud43	52	1	Ljunggren	Ljunggren	NNP
cord-355413-ls2nud43	52	2	and	and	CC
cord-355413-ls2nud43	52	3	colleagues	colleague	NNS
cord-355413-ls2nud43	52	4	have	have	VBP
cord-355413-ls2nud43	52	5	carried	carry	VBN
cord-355413-ls2nud43	52	6	out	out	RP
cord-355413-ls2nud43	52	7	a	a	DT
cord-355413-ls2nud43	52	8	series	series	NN
cord-355413-ls2nud43	52	9	of	of	IN
cord-355413-ls2nud43	52	10	well	well	RB
cord-355413-ls2nud43	52	11	-	-	HYPH
cord-355413-ls2nud43	52	12	designed	design	VBN
cord-355413-ls2nud43	52	13	studies	study	NNS
cord-355413-ls2nud43	52	14	addressing	address	VBG
cord-355413-ls2nud43	52	15	this	this	DT
cord-355413-ls2nud43	52	16	puzzling	puzzling	JJ
cord-355413-ls2nud43	52	17	phenomenon	phenomenon	NN
cord-355413-ls2nud43	52	18	.	.	.
cord-355413-ls2nud43	53	1	Initially	initially	RB
cord-355413-ls2nud43	53	2	,	,	,
cord-355413-ls2nud43	53	3	it	-PRON-	PRP
cord-355413-ls2nud43	53	4	was	be	VBD
cord-355413-ls2nud43	53	5	demonstrated	demonstrate	VBN
cord-355413-ls2nud43	53	6	that	that	IN
cord-355413-ls2nud43	53	7	NK	NK	NNP
cord-355413-ls2nud43	53	8	cells	cell	NNS
cord-355413-ls2nud43	53	9	could	could	MD
cord-355413-ls2nud43	53	10	readily	readily	RB
cord-355413-ls2nud43	53	11	kill	kill	VB
cord-355413-ls2nud43	53	12	syngeneic	syngeneic	NNS
cord-355413-ls2nud43	53	13	dorsal	dorsal	JJ
cord-355413-ls2nud43	53	14	root	root	NN
cord-355413-ls2nud43	53	15	ganglia	ganglion	NNS
cord-355413-ls2nud43	53	16	(	(	-LRB-
cord-355413-ls2nud43	53	17	DRG	DRG	NNP
cord-355413-ls2nud43	53	18	)	)	-RRB-
cord-355413-ls2nud43	53	19	neurons	neuron	NNS
cord-355413-ls2nud43	53	20	by	by	IN
cord-355413-ls2nud43	53	21	a	a	DT
cord-355413-ls2nud43	53	22	perforin	perforin	NN
cord-355413-ls2nud43	53	23	-	-	HYPH
cord-355413-ls2nud43	53	24	dependent	dependent	JJ
cord-355413-ls2nud43	53	25	mechanism	mechanism	NN
cord-355413-ls2nud43	53	26	(	(	-LRB-
cord-355413-ls2nud43	53	27	Backstrom	Backstrom	NNP
cord-355413-ls2nud43	53	28	et	et	NNP
cord-355413-ls2nud43	53	29	al	al	NNP
cord-355413-ls2nud43	53	30	.	.	NNP
cord-355413-ls2nud43	53	31	,	,	,
cord-355413-ls2nud43	53	32	2000	2000	CD
cord-355413-ls2nud43	53	33	(	(	-LRB-
cord-355413-ls2nud43	53	34	Backstrom	Backstrom	NNP
cord-355413-ls2nud43	53	35	et	et	NNP
cord-355413-ls2nud43	53	36	al	al	NNP
cord-355413-ls2nud43	53	37	.	.	NNP
cord-355413-ls2nud43	53	38	,	,	,
cord-355413-ls2nud43	53	39	,	,	,
cord-355413-ls2nud43	53	40	2003	2003	CD
cord-355413-ls2nud43	53	41	.	.	.
cord-355413-ls2nud43	54	1	Ventral	ventral	JJ
cord-355413-ls2nud43	54	2	spinal	spinal	JJ
cord-355413-ls2nud43	54	3	cord	cord	NN
cord-355413-ls2nud43	54	4	neurons	neuron	NNS
cord-355413-ls2nud43	54	5	and	and	CC
cord-355413-ls2nud43	54	6	hippocampal	hippocampal	JJ
cord-355413-ls2nud43	54	7	neurons	neuron	NNS
cord-355413-ls2nud43	54	8	of	of	IN
cord-355413-ls2nud43	54	9	the	the	DT
cord-355413-ls2nud43	54	10	CNS	CNS	NNP
cord-355413-ls2nud43	54	11	were	be	VBD
cord-355413-ls2nud43	54	12	resistant	resistant	JJ
cord-355413-ls2nud43	54	13	to	to	IN
cord-355413-ls2nud43	54	14	lysis	lysis	NN
cord-355413-ls2nud43	54	15	.	.	.
cord-355413-ls2nud43	55	1	The	the	DT
cord-355413-ls2nud43	55	2	resistance	resistance	NN
cord-355413-ls2nud43	55	3	to	to	IN
cord-355413-ls2nud43	55	4	NK	NK	NNP
cord-355413-ls2nud43	55	5	cell	cell	NN
cord-355413-ls2nud43	55	6	-	-	HYPH
cord-355413-ls2nud43	55	7	mediated	mediate	VBN
cord-355413-ls2nud43	55	8	lysis	lysis	NN
cord-355413-ls2nud43	55	9	of	of	IN
cord-355413-ls2nud43	55	10	the	the	DT
cord-355413-ls2nud43	55	11	latter	latter	JJ
cord-355413-ls2nud43	55	12	neurons	neuron	NNS
cord-355413-ls2nud43	55	13	was	be	VBD
cord-355413-ls2nud43	55	14	not	not	RB
cord-355413-ls2nud43	55	15	related	relate	VBN
cord-355413-ls2nud43	55	16	to	to	IN
cord-355413-ls2nud43	55	17	protection	protection	NN
cord-355413-ls2nud43	55	18	by	by	IN
cord-355413-ls2nud43	55	19	MHC	MHC	NNP
cord-355413-ls2nud43	55	20	class	class	NN
cord-355413-ls2nud43	56	1	I	-PRON-	PRP
cord-355413-ls2nud43	56	2	molecules	molecule	NNS
cord-355413-ls2nud43	56	3	,	,	,
cord-355413-ls2nud43	56	4	since	since	IN
cord-355413-ls2nud43	56	5	similar	similar	JJ
cord-355413-ls2nud43	56	6			CD
cord-355413-ls2nud43	56	7	2	2	CD
cord-355413-ls2nud43	56	8	-micro	-micro	JJ
cord-355413-ls2nud43	56	9	-	-	HYPH
cord-355413-ls2nud43	56	10	globulin	globulin	NN
cord-355413-ls2nud43	56	11	/	/	NNS
cord-355413-ls2nud43	56	12	neurons	neuron	NNS
cord-355413-ls2nud43	56	13	were	be	VBD
cord-355413-ls2nud43	56	14	equally	equally	RB
cord-355413-ls2nud43	56	15	resistant	resistant	JJ
cord-355413-ls2nud43	56	16	to	to	IN
cord-355413-ls2nud43	56	17	lysis	lysis	NN
cord-355413-ls2nud43	56	18	(	(	-LRB-
cord-355413-ls2nud43	56	19	Backstrom	Backstrom	NNP
cord-355413-ls2nud43	56	20	et	et	NNP
cord-355413-ls2nud43	56	21	al	al	NNP
cord-355413-ls2nud43	56	22	.	.	NNP
cord-355413-ls2nud43	56	23	,	,	,
cord-355413-ls2nud43	56	24	2003	2003	CD
cord-355413-ls2nud43	56	25	)	)	-RRB-
cord-355413-ls2nud43	56	26	.	.	.
cord-355413-ls2nud43	57	1	NK	NK	NNP
cord-355413-ls2nud43	57	2	cell	cell	NN
cord-355413-ls2nud43	57	3	function	function	NN
cord-355413-ls2nud43	57	4	is	be	VBZ
cord-355413-ls2nud43	57	5	tightly	tightly	RB
cord-355413-ls2nud43	57	6	regulated	regulate	VBN
cord-355413-ls2nud43	57	7	by	by	IN
cord-355413-ls2nud43	57	8	multiple	multiple	JJ
cord-355413-ls2nud43	57	9	signals	signal	NNS
cord-355413-ls2nud43	57	10	transmitted	transmit	VBN
cord-355413-ls2nud43	57	11	via	via	IN
cord-355413-ls2nud43	57	12	inhibitory	inhibitory	JJ
cord-355413-ls2nud43	57	13	and	and	CC
cord-355413-ls2nud43	57	14	activating	activate	VBG
cord-355413-ls2nud43	57	15	receptors	receptor	NNS
cord-355413-ls2nud43	57	16	.	.	.
cord-355413-ls2nud43	58	1	The	the	DT
cord-355413-ls2nud43	58	2	prerequisite	prerequisite	NN
cord-355413-ls2nud43	58	3	for	for	IN
cord-355413-ls2nud43	58	4	NK	NK	NNP
cord-355413-ls2nud43	58	5	cell	cell	NN
cord-355413-ls2nud43	58	6	killing	killing	NN
cord-355413-ls2nud43	58	7	is	be	VBZ
cord-355413-ls2nud43	58	8	its	-PRON-	PRP$
cord-355413-ls2nud43	58	9	activation	activation	NN
cord-355413-ls2nud43	58	10	via	via	IN
cord-355413-ls2nud43	58	11	signalling	signal	VBG
cord-355413-ls2nud43	58	12	from	from	IN
cord-355413-ls2nud43	58	13	activating	activate	VBG
cord-355413-ls2nud43	58	14	receptor	receptor	NN
cord-355413-ls2nud43	58	15	ligand	ligand	NN
cord-355413-ls2nud43	58	16	pathways	pathway	NNS
cord-355413-ls2nud43	58	17	.	.	.
cord-355413-ls2nud43	59	1	NK	NK	NNP
cord-355413-ls2nud43	59	2	cell	cell	NN
cord-355413-ls2nud43	59	3	activation	activation	NN
cord-355413-ls2nud43	59	4	generally	generally	RB
cord-355413-ls2nud43	59	5	appears	appear	VBZ
cord-355413-ls2nud43	59	6	to	to	TO
cord-355413-ls2nud43	59	7	be	be	VB
cord-355413-ls2nud43	59	8	elicited	elicit	VBN
cord-355413-ls2nud43	59	9	by	by	IN
cord-355413-ls2nud43	59	10	a	a	DT
cord-355413-ls2nud43	59	11	distinct	distinct	JJ
cord-355413-ls2nud43	59	12	set	set	NN
cord-355413-ls2nud43	59	13	of	of	IN
cord-355413-ls2nud43	59	14	molecules	molecule	NNS
cord-355413-ls2nud43	59	15	that	that	WDT
cord-355413-ls2nud43	59	16	have	have	VBP
cord-355413-ls2nud43	59	17	weak	weak	JJ
cord-355413-ls2nud43	59	18	homology	homology	NN
cord-355413-ls2nud43	59	19	with	with	IN
cord-355413-ls2nud43	59	20	MHC	MHC	NNP
cord-355413-ls2nud43	59	21	class	class	NN
cord-355413-ls2nud43	59	22	I	-PRON-	PRP
cord-355413-ls2nud43	59	23	molecules	molecule	NNS
cord-355413-ls2nud43	59	24	.	.	.
cord-355413-ls2nud43	60	1	The	the	DT
cord-355413-ls2nud43	60	2	activating	activate	VBG
cord-355413-ls2nud43	60	3	receptor	receptor	NN
cord-355413-ls2nud43	60	4	NKG2D	nkg2d	CD
cord-355413-ls2nud43	60	5	which	which	WDT
cord-355413-ls2nud43	60	6	differs	differ	VBZ
cord-355413-ls2nud43	60	7	dramatically	dramatically	RB
cord-355413-ls2nud43	60	8	from	from	IN
cord-355413-ls2nud43	60	9	other	other	JJ
cord-355413-ls2nud43	60	10	NKG2	NKG2	NNP
cord-355413-ls2nud43	60	11	receptor	receptor	NN
cord-355413-ls2nud43	60	12	proteins	protein	NNS
cord-355413-ls2nud43	60	13	is	be	VBZ
cord-355413-ls2nud43	60	14	of	of	IN
cord-355413-ls2nud43	60	15	particular	particular	JJ
cord-355413-ls2nud43	60	16	interest	interest	NN
cord-355413-ls2nud43	60	17	since	since	IN
cord-355413-ls2nud43	60	18	it	-PRON-	PRP
cord-355413-ls2nud43	60	19	,	,	,
cord-355413-ls2nud43	60	20	in	in	IN
cord-355413-ls2nud43	60	21	contrast	contrast	NN
cord-355413-ls2nud43	60	22	to	to	IN
cord-355413-ls2nud43	60	23	other	other	JJ
cord-355413-ls2nud43	60	24	NK	NK	NNP
cord-355413-ls2nud43	60	25	cell	cell	NN
cord-355413-ls2nud43	60	26	-	-	HYPH
cord-355413-ls2nud43	60	27	activating	activate	VBG
cord-355413-ls2nud43	60	28	receptors	receptor	NNS
cord-355413-ls2nud43	60	29	,	,	,
cord-355413-ls2nud43	60	30	is	be	VBZ
cord-355413-ls2nud43	60	31	constitutively	constitutively	RB
cord-355413-ls2nud43	60	32	expressed	express	VBN
cord-355413-ls2nud43	60	33	on	on	IN
cord-355413-ls2nud43	60	34	NK	NK	NNP
cord-355413-ls2nud43	60	35	cells	cell	NNS
cord-355413-ls2nud43	60	36	.	.	.
cord-355413-ls2nud43	61	1	The	the	DT
cord-355413-ls2nud43	61	2	endogenous	endogenous	JJ
cord-355413-ls2nud43	61	3	ligand	ligand	NN
cord-355413-ls2nud43	61	4	of	of	IN
cord-355413-ls2nud43	61	5	NKG2D	nkg2d	CD
cord-355413-ls2nud43	61	6	in	in	IN
cord-355413-ls2nud43	61	7	the	the	DT
cord-355413-ls2nud43	61	8	mouse	mouse	NN
cord-355413-ls2nud43	61	9	was	be	VBD
cord-355413-ls2nud43	61	10	recently	recently	RB
cord-355413-ls2nud43	61	11	identified	identify	VBN
cord-355413-ls2nud43	61	12	as	as	IN
cord-355413-ls2nud43	61	13	retinoic	retinoic	JJ
cord-355413-ls2nud43	61	14	acid	acid	NN
cord-355413-ls2nud43	61	15	early	early	RB
cord-355413-ls2nud43	61	16	inducible	inducible	JJ
cord-355413-ls2nud43	61	17	gene-1	gene-1	NNP
cord-355413-ls2nud43	61	18	(	(	-LRB-
cord-355413-ls2nud43	61	19	RAE-1)-encoded	rae-1)-encoded	JJ
cord-355413-ls2nud43	61	20	proteins	protein	NNS
cord-355413-ls2nud43	61	21	and	and	CC
cord-355413-ls2nud43	61	22	minor	minor	JJ
cord-355413-ls2nud43	61	23	histocompatibility	histocompatibility	NN
cord-355413-ls2nud43	61	24	antigen	antigen	NN
cord-355413-ls2nud43	61	25	H60	H60	NNP
cord-355413-ls2nud43	61	26	(	(	-LRB-
cord-355413-ls2nud43	61	27	Cerwenka	Cerwenka	NNP
cord-355413-ls2nud43	61	28	et	et	NNP
cord-355413-ls2nud43	61	29	al	al	NNP
cord-355413-ls2nud43	61	30	.	.	NNP
cord-355413-ls2nud43	61	31	,	,	,
cord-355413-ls2nud43	61	32	2000	2000	CD
cord-355413-ls2nud43	61	33	;	;	:
cord-355413-ls2nud43	62	1	Diefenbach	Diefenbach	NNP
cord-355413-ls2nud43	62	2	et	et	FW
cord-355413-ls2nud43	62	3	al	al	NNP
cord-355413-ls2nud43	62	4	.	.	NNP
cord-355413-ls2nud43	62	5	,	,	,
cord-355413-ls2nud43	62	6	2000	2000	CD
cord-355413-ls2nud43	63	1	;	;	:
cord-355413-ls2nud43	63	2	Malarkannan	Malarkannan	NNP
cord-355413-ls2nud43	63	3	et	et	NNP
cord-355413-ls2nud43	63	4	al	al	NNP
cord-355413-ls2nud43	63	5	.	.	NNP
cord-355413-ls2nud43	63	6	,	,	,
cord-355413-ls2nud43	63	7	1998	1998	CD
cord-355413-ls2nud43	63	8	)	)	-RRB-
cord-355413-ls2nud43	63	9	.	.	.
cord-355413-ls2nud43	64	1	Differential	differential	JJ
cord-355413-ls2nud43	64	2	expression	expression	NN
cord-355413-ls2nud43	64	3	of	of	IN
cord-355413-ls2nud43	64	4	NKG2D	nkg2d	CD
cord-355413-ls2nud43	64	5	and	and	CC
cord-355413-ls2nud43	64	6	its	-PRON-	PRP$
cord-355413-ls2nud43	64	7	ligand	ligand	NN
cord-355413-ls2nud43	64	8	on	on	IN
cord-355413-ls2nud43	64	9	neuronal	neuronal	JJ
cord-355413-ls2nud43	64	10	cells	cell	NNS
cord-355413-ls2nud43	64	11	from	from	IN
cord-355413-ls2nud43	64	12	the	the	DT
cord-355413-ls2nud43	64	13	peripheral	peripheral	JJ
cord-355413-ls2nud43	64	14	system	system	NN
cord-355413-ls2nud43	64	15	or	or	CC
cord-355413-ls2nud43	64	16	the	the	DT
cord-355413-ls2nud43	64	17	CNS	CNS	NNP
cord-355413-ls2nud43	64	18	appears	appear	VBZ
cord-355413-ls2nud43	64	19	a	a	DT
cord-355413-ls2nud43	64	20	key	key	JJ
cord-355413-ls2nud43	64	21	mechanism	mechanism	NN
cord-355413-ls2nud43	64	22	underlying	underlie	VBG
cord-355413-ls2nud43	64	23	variable	variable	JJ
cord-355413-ls2nud43	64	24	susceptibility	susceptibility	NN
cord-355413-ls2nud43	64	25	to	to	IN
cord-355413-ls2nud43	64	26	NK	NK	NNP
cord-355413-ls2nud43	64	27	lyses	lyse	VBZ
cord-355413-ls2nud43	64	28	.	.	.
cord-355413-ls2nud43	65	1	RAE-1	RAE-1	NNP
cord-355413-ls2nud43	65	2	,	,	,
cord-355413-ls2nud43	65	3	the	the	DT
cord-355413-ls2nud43	65	4	product	product	NN
cord-355413-ls2nud43	65	5	of	of	IN
cord-355413-ls2nud43	65	6	which	which	WDT
cord-355413-ls2nud43	65	7	is	be	VBZ
cord-355413-ls2nud43	65	8	a	a	DT
cord-355413-ls2nud43	65	9	ligand	ligand	NN
cord-355413-ls2nud43	65	10	for	for	IN
cord-355413-ls2nud43	65	11	the	the	DT
cord-355413-ls2nud43	65	12	NK	NK	NNP
cord-355413-ls2nud43	65	13	cell	cell	NN
cord-355413-ls2nud43	65	14	-	-	HYPH
cord-355413-ls2nud43	65	15	activating	activate	VBG
cord-355413-ls2nud43	65	16	receptor	receptor	NN
cord-355413-ls2nud43	65	17	NKG2D	nkg2d	NN
cord-355413-ls2nud43	65	18	,	,	,
cord-355413-ls2nud43	65	19	was	be	VBD
cord-355413-ls2nud43	65	20	expressed	express	VBN
cord-355413-ls2nud43	65	21	at	at	IN
cord-355413-ls2nud43	65	22	high	high	JJ
cord-355413-ls2nud43	65	23	levels	level	NNS
cord-355413-ls2nud43	65	24	in	in	IN
cord-355413-ls2nud43	65	25	the	the	DT
cord-355413-ls2nud43	65	26	DRG	DRG	NNP
cord-355413-ls2nud43	65	27	neurons	neuron	NNS
cord-355413-ls2nud43	65	28	.	.	.
cord-355413-ls2nud43	66	1	In	in	IN
cord-355413-ls2nud43	66	2	contrast	contrast	NN
cord-355413-ls2nud43	66	3	,	,	,
cord-355413-ls2nud43	66	4	RAE-1	RAE-1	NNP
cord-355413-ls2nud43	66	5	was	be	VBD
cord-355413-ls2nud43	66	6	expressed	express	VBN
cord-355413-ls2nud43	66	7	only	only	RB
cord-355413-ls2nud43	66	8	at	at	IN
cord-355413-ls2nud43	66	9	very	very	RB
cord-355413-ls2nud43	66	10	low	low	JJ
cord-355413-ls2nud43	66	11	levels	level	NNS
cord-355413-ls2nud43	66	12	in	in	IN
cord-355413-ls2nud43	66	13	the	the	DT
cord-355413-ls2nud43	66	14	resistant	resistant	JJ
cord-355413-ls2nud43	66	15	CNS	CNS	NNP
cord-355413-ls2nud43	66	16	-	-	HYPH
cord-355413-ls2nud43	66	17	derived	derive	VBN
cord-355413-ls2nud43	66	18	neurons	neuron	NNS
cord-355413-ls2nud43	66	19	.	.	.
cord-355413-ls2nud43	67	1	Blocking	block	VBG
cord-355413-ls2nud43	67	2	NK	NK	NNP
cord-355413-ls2nud43	67	3	cells	cell	NNS
cord-355413-ls2nud43	67	4	with	with	IN
cord-355413-ls2nud43	67	5	anti	anti	JJ
cord-355413-ls2nud43	67	6	-	-	JJ
cord-355413-ls2nud43	67	7	NKG2D	nkg2d	JJ
cord-355413-ls2nud43	67	8	antibodies	antibody	NNS
cord-355413-ls2nud43	67	9	inhibited	inhibit	VBD
cord-355413-ls2nud43	67	10	NK	NK	NNP
cord-355413-ls2nud43	67	11	cell	cell	NN
cord-355413-ls2nud43	67	12	-	-	HYPH
cord-355413-ls2nud43	67	13	mediated	mediate	VBN
cord-355413-ls2nud43	67	14	killing	killing	NN
cord-355413-ls2nud43	67	15	of	of	IN
cord-355413-ls2nud43	67	16	the	the	DT
cord-355413-ls2nud43	67	17	DRG	DRG	NNP
cord-355413-ls2nud43	67	18	neurons	neuron	NNS
cord-355413-ls2nud43	67	19	.	.	.
cord-355413-ls2nud43	68	1	These	these	DT
cord-355413-ls2nud43	68	2	findings	finding	NNS
cord-355413-ls2nud43	68	3	are	be	VBP
cord-355413-ls2nud43	68	4	important	important	JJ
cord-355413-ls2nud43	68	5	in	in	IN
cord-355413-ls2nud43	68	6	revealing	reveal	VBG
cord-355413-ls2nud43	68	7	novel	novel	JJ
cord-355413-ls2nud43	68	8	immunopathologic	immunopathologic	JJ
cord-355413-ls2nud43	68	9	effects	effect	NNS
cord-355413-ls2nud43	68	10	of	of	IN
cord-355413-ls2nud43	68	11	several	several	JJ
cord-355413-ls2nud43	68	12	CNS	CNS	NNP
cord-355413-ls2nud43	68	13	diseases	disease	NNS
cord-355413-ls2nud43	68	14	.	.	.
cord-355413-ls2nud43	69	1	Indeed	indeed	RB
cord-355413-ls2nud43	69	2	,	,	,
cord-355413-ls2nud43	69	3	progressive	progressive	JJ
cord-355413-ls2nud43	69	4	motor	motor	NN
cord-355413-ls2nud43	69	5	and	and	CC
cord-355413-ls2nud43	69	6	sensory	sensory	JJ
cord-355413-ls2nud43	69	7	neuropathy	neuropathy	NN
cord-355413-ls2nud43	69	8	developed	develop	VBN
cord-355413-ls2nud43	69	9	in	in	IN
cord-355413-ls2nud43	69	10	a	a	DT
cord-355413-ls2nud43	69	11	patient	patient	NN
cord-355413-ls2nud43	69	12	with	with	IN
cord-355413-ls2nud43	69	13	chronic	chronic	JJ
cord-355413-ls2nud43	69	14	NK	NK	NNP
cord-355413-ls2nud43	69	15	cell	cell	NN
cord-355413-ls2nud43	69	16	lymphocytosis	lymphocytosis	NN
cord-355413-ls2nud43	69	17	(	(	-LRB-
cord-355413-ls2nud43	69	18	CNKL	CNKL	NNP
cord-355413-ls2nud43	69	19	)	)	-RRB-
cord-355413-ls2nud43	70	1	(	(	-LRB-
cord-355413-ls2nud43	70	2	Noguchi	Noguchi	NNP
cord-355413-ls2nud43	70	3	et	et	NNP
cord-355413-ls2nud43	70	4	al	al	NNP
cord-355413-ls2nud43	70	5	.	.	NNP
cord-355413-ls2nud43	70	6	,	,	,
cord-355413-ls2nud43	70	7	2005	2005	CD
cord-355413-ls2nud43	70	8	)	)	-RRB-
cord-355413-ls2nud43	70	9	.	.	.
cord-355413-ls2nud43	71	1	A	a	DT
cord-355413-ls2nud43	71	2	sural	sural	JJ
cord-355413-ls2nud43	71	3	nerve	nerve	NN
cord-355413-ls2nud43	71	4	biopsy	biopsy	NN
cord-355413-ls2nud43	71	5	revealed	reveal	VBD
cord-355413-ls2nud43	71	6	infiltration	infiltration	NN
cord-355413-ls2nud43	71	7	of	of	IN
cord-355413-ls2nud43	71	8	NK	NK	NNP
cord-355413-ls2nud43	71	9	cells	cell	NNS
cord-355413-ls2nud43	71	10	into	into	IN
cord-355413-ls2nud43	71	11	the	the	DT
cord-355413-ls2nud43	71	12	nerve	nerve	NN
cord-355413-ls2nud43	71	13	fascicles	fascicle	NNS
cord-355413-ls2nud43	71	14	,	,	,
cord-355413-ls2nud43	71	15	and	and	CC
cord-355413-ls2nud43	71	16	demyelinating	demyelinating	JJ
cord-355413-ls2nud43	71	17	changes	change	NNS
cord-355413-ls2nud43	71	18	with	with	IN
cord-355413-ls2nud43	71	19	secondary	secondary	JJ
cord-355413-ls2nud43	71	20	axonal	axonal	JJ
cord-355413-ls2nud43	71	21	degeneration	degeneration	NN
cord-355413-ls2nud43	71	22	.	.	.
cord-355413-ls2nud43	72	1	The	the	DT
cord-355413-ls2nud43	72	2	infiltrating	infiltrate	VBG
cord-355413-ls2nud43	72	3	NK	NK	NNP
cord-355413-ls2nud43	72	4	cells	cell	NNS
cord-355413-ls2nud43	72	5	were	be	VBD
cord-355413-ls2nud43	72	6	adjacent	adjacent	JJ
cord-355413-ls2nud43	72	7	to	to	IN
cord-355413-ls2nud43	72	8	myelinated	myelinated	JJ
cord-355413-ls2nud43	72	9	fibres	fibre	NNS
cord-355413-ls2nud43	72	10	,	,	,
cord-355413-ls2nud43	72	11	showing	show	VBG
cord-355413-ls2nud43	72	12	damage	damage	NN
cord-355413-ls2nud43	72	13	of	of	IN
cord-355413-ls2nud43	72	14	Schwann	Schwann	NNP
cord-355413-ls2nud43	72	15	cell	cell	NN
cord-355413-ls2nud43	72	16	membranes	membrane	NNS
cord-355413-ls2nud43	72	17	.	.	.
cord-355413-ls2nud43	73	1	Treatment	treatment	NN
cord-355413-ls2nud43	73	2	with	with	IN
cord-355413-ls2nud43	73	3	oral	oral	JJ
cord-355413-ls2nud43	73	4	prednisolone	prednisolone	NN
cord-355413-ls2nud43	73	5	resulted	result	VBD
cord-355413-ls2nud43	73	6	in	in	IN
cord-355413-ls2nud43	73	7	rapid	rapid	JJ
cord-355413-ls2nud43	73	8	improvement	improvement	NN
cord-355413-ls2nud43	73	9	of	of	IN
cord-355413-ls2nud43	73	10	sensory	sensory	JJ
cord-355413-ls2nud43	73	11	disturbance	disturbance	NN
cord-355413-ls2nud43	73	12	and	and	CC
cord-355413-ls2nud43	73	13	weakness	weakness	NN
cord-355413-ls2nud43	73	14	with	with	IN
cord-355413-ls2nud43	73	15	a	a	DT
cord-355413-ls2nud43	73	16	significant	significant	JJ
cord-355413-ls2nud43	73	17	decrease	decrease	NN
cord-355413-ls2nud43	73	18	of	of	IN
cord-355413-ls2nud43	73	19	NK	NK	NNP
cord-355413-ls2nud43	73	20	cells	cell	NNS
cord-355413-ls2nud43	73	21	in	in	IN
cord-355413-ls2nud43	73	22	the	the	DT
cord-355413-ls2nud43	73	23	blood	blood	NN
cord-355413-ls2nud43	73	24	and	and	CC
cord-355413-ls2nud43	73	25	disappearance	disappearance	NN
cord-355413-ls2nud43	73	26	of	of	IN
cord-355413-ls2nud43	73	27	the	the	DT
cord-355413-ls2nud43	73	28	conduction	conduction	NN
cord-355413-ls2nud43	73	29	block	block	NN
cord-355413-ls2nud43	73	30	.	.	.
cord-355413-ls2nud43	74	1	These	these	DT
cord-355413-ls2nud43	74	2	observations	observation	NNS
cord-355413-ls2nud43	74	3	suggest	suggest	VBP
cord-355413-ls2nud43	74	4	that	that	IN
cord-355413-ls2nud43	74	5	the	the	DT
cord-355413-ls2nud43	74	6	infiltrating	infiltrate	VBG
cord-355413-ls2nud43	74	7	NK	NK	NNP
cord-355413-ls2nud43	74	8	cells	cell	NNS
cord-355413-ls2nud43	74	9	may	may	MD
cord-355413-ls2nud43	74	10	directly	directly	RB
cord-355413-ls2nud43	74	11	damage	damage	VB
cord-355413-ls2nud43	74	12	myelin	myelin	NN
cord-355413-ls2nud43	74	13	and	and	CC
cord-355413-ls2nud43	74	14	Schwann	Schwann	NNP
cord-355413-ls2nud43	74	15	cells	cell	NNS
cord-355413-ls2nud43	74	16	,	,	,
cord-355413-ls2nud43	74	17	thus	thus	RB
cord-355413-ls2nud43	74	18	causing	cause	VBG
cord-355413-ls2nud43	74	19	demyelination	demyelination	NN
cord-355413-ls2nud43	74	20	.	.	.
cord-355413-ls2nud43	75	1	Since	since	IN
cord-355413-ls2nud43	75	2	expression	expression	NN
cord-355413-ls2nud43	75	3	of	of	IN
cord-355413-ls2nud43	75	4	NKG2D	nkg2d	NN
cord-355413-ls2nud43	75	5	ligands	ligand	NNS
cord-355413-ls2nud43	75	6	is	be	VBZ
cord-355413-ls2nud43	75	7	likely	likely	RB
cord-355413-ls2nud43	75	8	regulated	regulate	VBN
cord-355413-ls2nud43	75	9	by	by	IN
cord-355413-ls2nud43	75	10	viral	viral	JJ
cord-355413-ls2nud43	75	11	infection	infection	NN
cord-355413-ls2nud43	75	12	or	or	CC
cord-355413-ls2nud43	75	13	transformation	transformation	NN
cord-355413-ls2nud43	75	14	,	,	,
cord-355413-ls2nud43	75	15	and	and	CC
cord-355413-ls2nud43	75	16	the	the	DT
cord-355413-ls2nud43	75	17	inhibitory	inhibitory	JJ
cord-355413-ls2nud43	75	18	MHC	MHC	NNP
cord-355413-ls2nud43	75	19	class	class	NN
cord-355413-ls2nud43	75	20	I	-PRON-	PRP
cord-355413-ls2nud43	75	21	expression	expression	NN
cord-355413-ls2nud43	75	22	is	be	VBZ
cord-355413-ls2nud43	75	23	low	low	JJ
cord-355413-ls2nud43	75	24	or	or	CC
cord-355413-ls2nud43	75	25	absent	absent	JJ
cord-355413-ls2nud43	75	26	in	in	IN
cord-355413-ls2nud43	75	27	the	the	DT
cord-355413-ls2nud43	75	28	nervous	nervous	JJ
cord-355413-ls2nud43	75	29	system	system	NN
cord-355413-ls2nud43	75	30	,	,	,
cord-355413-ls2nud43	75	31	it	-PRON-	PRP
cord-355413-ls2nud43	75	32	is	be	VBZ
cord-355413-ls2nud43	75	33	plausible	plausible	JJ
cord-355413-ls2nud43	75	34	that	that	IN
cord-355413-ls2nud43	75	35	a	a	DT
cord-355413-ls2nud43	75	36	viral	viral	JJ
cord-355413-ls2nud43	75	37	infection	infection	NN
cord-355413-ls2nud43	75	38	or	or	CC
cord-355413-ls2nud43	75	39	transformation	transformation	NN
cord-355413-ls2nud43	75	40	could	could	MD
cord-355413-ls2nud43	75	41	well	well	RB
cord-355413-ls2nud43	75	42	break	break	VB
cord-355413-ls2nud43	75	43	the	the	DT
cord-355413-ls2nud43	75	44	balance	balance	NN
cord-355413-ls2nud43	75	45	of	of	IN
cord-355413-ls2nud43	75	46	activating	activate	VBG
cord-355413-ls2nud43	75	47	/	/	SYM
cord-355413-ls2nud43	75	48	inhibiting	inhibit	VBG
cord-355413-ls2nud43	75	49	activities	activity	NNS
cord-355413-ls2nud43	75	50	on	on	IN
cord-355413-ls2nud43	75	51	NK	NK	NNP
cord-355413-ls2nud43	75	52	cells	cell	NNS
cord-355413-ls2nud43	75	53	,	,	,
cord-355413-ls2nud43	75	54	and	and	CC
cord-355413-ls2nud43	75	55	NK	NK	NNP
cord-355413-ls2nud43	75	56	cell	cell	NN
cord-355413-ls2nud43	75	57	-	-	HYPH
cord-355413-ls2nud43	75	58	mediated	mediate	VBN
cord-355413-ls2nud43	75	59	immune	immune	JJ
cord-355413-ls2nud43	75	60	pathology	pathology	NN
cord-355413-ls2nud43	75	61	would	would	MD
cord-355413-ls2nud43	75	62	occur	occur	VB
cord-355413-ls2nud43	75	63	in	in	IN
cord-355413-ls2nud43	75	64	such	such	JJ
cord-355413-ls2nud43	75	65	circumstances	circumstance	NNS
cord-355413-ls2nud43	75	66	.	.	.
cord-355413-ls2nud43	76	1	Human	human	JJ
cord-355413-ls2nud43	76	2	oligodendrocytes	oligodendrocyte	NNS
cord-355413-ls2nud43	76	3	do	do	VBP
cord-355413-ls2nud43	76	4	not	not	RB
cord-355413-ls2nud43	76	5	express	express	VB
cord-355413-ls2nud43	76	6	MHC	MHC	NNP
cord-355413-ls2nud43	76	7	class	class	NN
cord-355413-ls2nud43	76	8	II	II	NNP
cord-355413-ls2nud43	76	9	molecules	molecule	NNS
cord-355413-ls2nud43	76	10	;	;	:
cord-355413-ls2nud43	76	11	thus	thus	RB
cord-355413-ls2nud43	76	12	,	,	,
cord-355413-ls2nud43	76	13	direct	direct	JJ
cord-355413-ls2nud43	76	14	MHC	MHC	NNP
cord-355413-ls2nud43	76	15	-	-	HYPH
cord-355413-ls2nud43	76	16	restricted	restrict	VBN
cord-355413-ls2nud43	76	17	injury	injury	NN
cord-355413-ls2nud43	76	18	mediated	mediate	VBN
cord-355413-ls2nud43	76	19	by	by	IN
cord-355413-ls2nud43	76	20	myelin	myelin	NN
cord-355413-ls2nud43	76	21	-	-	HYPH
cord-355413-ls2nud43	76	22	reactive	reactive	JJ
cord-355413-ls2nud43	76	23	CD4	CD4	NNP
cord-355413-ls2nud43	76	24			NNP
cord-355413-ls2nud43	76	25	T	T	NNP
cord-355413-ls2nud43	76	26	cells	cell	NNS
cord-355413-ls2nud43	76	27	is	be	VBZ
cord-355413-ls2nud43	76	28	less	less	RBR
cord-355413-ls2nud43	76	29	likely	likely	JJ
cord-355413-ls2nud43	76	30	to	to	TO
cord-355413-ls2nud43	76	31	occur	occur	VB
cord-355413-ls2nud43	76	32	.	.	.
cord-355413-ls2nud43	77	1	The	the	DT
cord-355413-ls2nud43	77	2	migration	migration	NN
cord-355413-ls2nud43	77	3	of	of	IN
cord-355413-ls2nud43	77	4	NK	NK	NNP
cord-355413-ls2nud43	77	5	cells	cell	NNS
cord-355413-ls2nud43	77	6	to	to	IN
cord-355413-ls2nud43	77	7	the	the	DT
cord-355413-ls2nud43	77	8	CNS	CNS	NNP
cord-355413-ls2nud43	77	9	during	during	IN
cord-355413-ls2nud43	77	10	inflammatory	inflammatory	JJ
cord-355413-ls2nud43	77	11	responses	response	NNS
cord-355413-ls2nud43	77	12	and	and	CC
cord-355413-ls2nud43	77	13	lack	lack	NN
cord-355413-ls2nud43	77	14	of	of	IN
cord-355413-ls2nud43	77	15	inhibitory	inhibitory	JJ
cord-355413-ls2nud43	77	16	signal	signal	NN
cord-355413-ls2nud43	77	17	MHC	MHC	NNP
cord-355413-ls2nud43	77	18	class	class	NN
cord-355413-ls2nud43	77	19	I	-PRON-	PRP
cord-355413-ls2nud43	77	20	expression	expression	NN
cord-355413-ls2nud43	77	21	within	within	IN
cord-355413-ls2nud43	77	22	the	the	DT
cord-355413-ls2nud43	77	23	CNS	CNS	NNP
cord-355413-ls2nud43	77	24	invites	invite	VBZ
cord-355413-ls2nud43	77	25	prediction	prediction	NN
cord-355413-ls2nud43	77	26	that	that	IN
cord-355413-ls2nud43	77	27	direct	direct	JJ
cord-355413-ls2nud43	77	28	cytolytic	cytolytic	JJ
cord-355413-ls2nud43	77	29	effects	effect	NNS
cord-355413-ls2nud43	77	30	of	of	IN
cord-355413-ls2nud43	77	31	NK	NK	NNP
cord-355413-ls2nud43	77	32	cells	cell	NNS
cord-355413-ls2nud43	77	33	contribute	contribute	VBP
cord-355413-ls2nud43	77	34	to	to	IN
cord-355413-ls2nud43	77	35	oligodendrocyte	oligodendrocyte	NNP
cord-355413-ls2nud43	77	36	damage	damage	NN
cord-355413-ls2nud43	77	37	and	and	CC
cord-355413-ls2nud43	77	38	demyelination	demyelination	NN
cord-355413-ls2nud43	77	39	to	to	IN
cord-355413-ls2nud43	77	40	CNS	CNS	NNP
cord-355413-ls2nud43	77	41	diseases	disease	NNS
cord-355413-ls2nud43	77	42	such	such	JJ
cord-355413-ls2nud43	77	43	as	as	IN
cord-355413-ls2nud43	77	44	MS	MS	NNP
cord-355413-ls2nud43	77	45	.	.	.
cord-355413-ls2nud43	78	1	Antel	Antel	NNP
cord-355413-ls2nud43	78	2	and	and	CC
cord-355413-ls2nud43	78	3	colleagues	colleague	NNS
cord-355413-ls2nud43	78	4	demonstrated	demonstrate	VBD
cord-355413-ls2nud43	78	5	using	use	VBG
cord-355413-ls2nud43	78	6	in	in	IN
cord-355413-ls2nud43	78	7	vitro	vitro	FW
cord-355413-ls2nud43	78	8	assays	assay	NNS
cord-355413-ls2nud43	78	9	that	that	IN
cord-355413-ls2nud43	78	10	human	human	JJ
cord-355413-ls2nud43	78	11	oligodendrocytes	oligodendrocyte	NNS
cord-355413-ls2nud43	78	12	,	,	,
cord-355413-ls2nud43	78	13	as	as	RB
cord-355413-ls2nud43	78	14	well	well	RB
cord-355413-ls2nud43	78	15	as	as	IN
cord-355413-ls2nud43	78	16	other	other	JJ
cord-355413-ls2nud43	78	17	glial	glial	JJ
cord-355413-ls2nud43	78	18	elements	element	NNS
cord-355413-ls2nud43	78	19	(	(	-LRB-
cord-355413-ls2nud43	78	20	astrocytes	astrocyte	NNS
cord-355413-ls2nud43	78	21	,	,	,
cord-355413-ls2nud43	78	22	microglia	microglia	NNP
cord-355413-ls2nud43	78	23	)	)	-RRB-
cord-355413-ls2nud43	78	24	,	,	,
cord-355413-ls2nud43	78	25	were	be	VBD
cord-355413-ls2nud43	78	26	susceptible	susceptible	JJ
cord-355413-ls2nud43	78	27	to	to	IN
cord-355413-ls2nud43	78	28	injury	injury	NN
cord-355413-ls2nud43	78	29	mediated	mediate	VBN
cord-355413-ls2nud43	78	30	by	by	IN
cord-355413-ls2nud43	78	31	peripheral	peripheral	JJ
cord-355413-ls2nud43	78	32	blood	blood	NN
cord-355413-ls2nud43	78	33	-	-	HYPH
cord-355413-ls2nud43	78	34	derived	derive	VBN
cord-355413-ls2nud43	78	35	mononuclear	mononuclear	JJ
cord-355413-ls2nud43	78	36	cell	cell	NN
cord-355413-ls2nud43	78	37	preparations	preparation	NNS
cord-355413-ls2nud43	78	38	(	(	-LRB-
cord-355413-ls2nud43	78	39	MNCs	MNCs	NNP
cord-355413-ls2nud43	78	40	)	)	-RRB-
cord-355413-ls2nud43	78	41	,	,	,
cord-355413-ls2nud43	78	42	which	which	WDT
cord-355413-ls2nud43	78	43	were	be	VBD
cord-355413-ls2nud43	78	44	enriched	enrich	VBN
cord-355413-ls2nud43	78	45	for	for	IN
cord-355413-ls2nud43	78	46	NK	NK	NNP
cord-355413-ls2nud43	78	47	cells	cell	NNS
cord-355413-ls2nud43	78	48	by	by	IN
cord-355413-ls2nud43	78	49	depleting	deplete	VBG
cord-355413-ls2nud43	78	50	CD3	CD3	NNP
cord-355413-ls2nud43	78	51			NNP
cord-355413-ls2nud43	78	52	,	,	,
cord-355413-ls2nud43	78	53	with	with	IN
cord-355413-ls2nud43	78	54	or	or	CC
cord-355413-ls2nud43	78	55	without	without	IN
cord-355413-ls2nud43	78	56	CD19	CD19	NNP
cord-355413-ls2nud43	78	57			NNP
cord-355413-ls2nud43	78	58	cells	cell	NNS
cord-355413-ls2nud43	78	59	through	through	IN
cord-355413-ls2nud43	78	60	the	the	DT
cord-355413-ls2nud43	78	61	use	use	NN
cord-355413-ls2nud43	78	62	of	of	IN
cord-355413-ls2nud43	78	63	either	either	CC
cord-355413-ls2nud43	78	64	magnetic	magnetic	JJ
cord-355413-ls2nud43	78	65	beads	bead	NNS
cord-355413-ls2nud43	78	66	or	or	CC
cord-355413-ls2nud43	78	67	cell	cell	NN
cord-355413-ls2nud43	78	68	sorting	sorting	NN
cord-355413-ls2nud43	79	1	(	(	-LRB-
cord-355413-ls2nud43	79	2	Antel	Antel	NNP
cord-355413-ls2nud43	79	3	et	et	NNP
cord-355413-ls2nud43	79	4	al	al	NNP
cord-355413-ls2nud43	79	5	.	.	NNP
cord-355413-ls2nud43	79	6	,	,	,
cord-355413-ls2nud43	79	7	1998	1998	CD
cord-355413-ls2nud43	79	8	;	;	:
cord-355413-ls2nud43	80	1	Morse	Morse	NNP
cord-355413-ls2nud43	80	2	et	et	NNP
cord-355413-ls2nud43	80	3	al	al	NNP
cord-355413-ls2nud43	80	4	.	.	NNP
cord-355413-ls2nud43	80	5	,	,	,
cord-355413-ls2nud43	80	6	2001	2001	CD
cord-355413-ls2nud43	80	7	)	)	-RRB-
cord-355413-ls2nud43	80	8	.	.	.
cord-355413-ls2nud43	81	1	Cytotoxic	cytotoxic	JJ
cord-355413-ls2nud43	81	2	effects	effect	NNS
cord-355413-ls2nud43	81	3	of	of	IN
cord-355413-ls2nud43	81	4	the	the	DT
cord-355413-ls2nud43	81	5	NK	NK	NNP
cord-355413-ls2nud43	81	6	cell	cell	NN
cord-355413-ls2nud43	81	7	-	-	HYPH
cord-355413-ls2nud43	81	8	enriched	enrich	VBN
cord-355413-ls2nud43	81	9	effectors	effector	NNS
cord-355413-ls2nud43	81	10	were	be	VBD
cord-355413-ls2nud43	81	11	dependant	dependant	JJ
cord-355413-ls2nud43	81	12	on	on	IN
cord-355413-ls2nud43	81	13	pre	pre	JJ
cord-355413-ls2nud43	81	14	-	-	NN
cord-355413-ls2nud43	81	15	exposure	exposure	NN
cord-355413-ls2nud43	81	16	of	of	IN
cord-355413-ls2nud43	81	17	these	these	DT
cord-355413-ls2nud43	81	18	cells	cell	NNS
cord-355413-ls2nud43	81	19	to	to	IN
cord-355413-ls2nud43	81	20	IL-2	IL-2	NNP
cord-355413-ls2nud43	81	21	.	.	.
cord-355413-ls2nud43	82	1	Furthermore	furthermore	RB
cord-355413-ls2nud43	82	2	,	,	,
cord-355413-ls2nud43	82	3	it	-PRON-	PRP
cord-355413-ls2nud43	82	4	was	be	VBD
cord-355413-ls2nud43	82	5	found	find	VBN
cord-355413-ls2nud43	82	6	that	that	IN
cord-355413-ls2nud43	82	7	autologous	autologous	JJ
cord-355413-ls2nud43	82	8	oligodendrocytes	oligodendrocyte	NNS
cord-355413-ls2nud43	82	9	were	be	VBD
cord-355413-ls2nud43	82	10	as	as	RB
cord-355413-ls2nud43	82	11	susceptible	susceptible	JJ
cord-355413-ls2nud43	82	12	to	to	IN
cord-355413-ls2nud43	82	13	injury	injury	NN
cord-355413-ls2nud43	82	14	mediated	mediate	VBN
cord-355413-ls2nud43	82	15	by	by	IN
cord-355413-ls2nud43	82	16	IL-2-activated	il-2-activated	CD
cord-355413-ls2nud43	82	17	NK	NK	NNP
cord-355413-ls2nud43	82	18	cells	cell	NNS
cord-355413-ls2nud43	82	19	as	as	IN
cord-355413-ls2nud43	82	20	were	be	VBD
cord-355413-ls2nud43	82	21	heterogonous	heterogonous	JJ
cord-355413-ls2nud43	82	22	oligodendrocytes	oligodendrocyte	NNS
cord-355413-ls2nud43	82	23	.	.	.
cord-355413-ls2nud43	83	1	In	in	IN
cord-355413-ls2nud43	83	2	searching	search	VBG
cord-355413-ls2nud43	83	3	for	for	IN
cord-355413-ls2nud43	83	4	receptor	receptor	NN
cord-355413-ls2nud43	83	5	ligand	ligand	NN
cord-355413-ls2nud43	83	6	pathways	pathway	NNS
cord-355413-ls2nud43	83	7	that	that	WDT
cord-355413-ls2nud43	83	8	control	control	VBP
cord-355413-ls2nud43	83	9	the	the	DT
cord-355413-ls2nud43	83	10	NK	NK	NNP
cord-355413-ls2nud43	83	11	cell	cell	NN
cord-355413-ls2nud43	83	12	and	and	CC
cord-355413-ls2nud43	83	13	oligodendrocyte	oligodendrocyte	NNP
cord-355413-ls2nud43	83	14	interactions	interaction	NNS
cord-355413-ls2nud43	83	15	,	,	,
cord-355413-ls2nud43	83	16	it	-PRON-	PRP
cord-355413-ls2nud43	83	17	was	be	VBD
cord-355413-ls2nud43	83	18	found	find	VBN
cord-355413-ls2nud43	83	19	that	that	IN
cord-355413-ls2nud43	83	20	human	human	JJ
cord-355413-ls2nud43	83	21	adult	adult	NN
cord-355413-ls2nud43	83	22	oligodendrocytes	oligodendrocyte	NNS
cord-355413-ls2nud43	83	23	and	and	CC
cord-355413-ls2nud43	83	24	foetal	foetal	JJ
cord-355413-ls2nud43	83	25	astrocytes	astrocyte	NNS
cord-355413-ls2nud43	83	26	expressed	express	VBD
cord-355413-ls2nud43	83	27	ligands	ligand	NNS
cord-355413-ls2nud43	83	28	for	for	IN
cord-355413-ls2nud43	83	29	NKG2D	nkg2d	CD
cord-355413-ls2nud43	83	30	in	in	IN
cord-355413-ls2nud43	83	31	vitro	vitro	FW
cord-355413-ls2nud43	83	32	,	,	,
cord-355413-ls2nud43	83	33	whereas	whereas	IN
cord-355413-ls2nud43	83	34	neurons	neuron	NNS
cord-355413-ls2nud43	83	35	,	,	,
cord-355413-ls2nud43	83	36	microglia	microglia	NNS
cord-355413-ls2nud43	83	37	,	,	,
cord-355413-ls2nud43	83	38	and	and	CC
cord-355413-ls2nud43	83	39	adult	adult	NN
cord-355413-ls2nud43	83	40	astrocytes	astrocyte	NNS
cord-355413-ls2nud43	83	41	did	do	VBD
cord-355413-ls2nud43	83	42	not	not	RB
cord-355413-ls2nud43	83	43	(	(	-LRB-
cord-355413-ls2nud43	83	44	Saikali	Saikali	NNP
cord-355413-ls2nud43	83	45	et	et	NNP
cord-355413-ls2nud43	83	46	al	al	NNP
cord-355413-ls2nud43	83	47	.	.	NNP
cord-355413-ls2nud43	83	48	,	,	,
cord-355413-ls2nud43	83	49	2007	2007	CD
cord-355413-ls2nud43	83	50	)	)	-RRB-
cord-355413-ls2nud43	83	51	.	.	.
cord-355413-ls2nud43	84	1	Disruption	disruption	NN
cord-355413-ls2nud43	84	2	of	of	IN
cord-355413-ls2nud43	84	3	the	the	DT
cord-355413-ls2nud43	84	4	NKG2D	nkg2d	NN
cord-355413-ls2nud43	84	5	-	-	HYPH
cord-355413-ls2nud43	84	6	NKG2D	nkg2d	NN
cord-355413-ls2nud43	84	7	ligand	ligand	NN
cord-355413-ls2nud43	84	8	interaction	interaction	NN
cord-355413-ls2nud43	84	9	using	use	VBG
cord-355413-ls2nud43	84	10	blocking	block	VBG
cord-355413-ls2nud43	84	11	antibodies	antibody	NNS
cord-355413-ls2nud43	84	12	significantly	significantly	RB
cord-355413-ls2nud43	84	13	inhibited	inhibit	VBD
cord-355413-ls2nud43	84	14	killing	killing	NN
cord-355413-ls2nud43	84	15	of	of	IN
cord-355413-ls2nud43	84	16	primary	primary	JJ
cord-355413-ls2nud43	84	17	human	human	JJ
cord-355413-ls2nud43	84	18	oligodendrocytes	oligodendrocyte	NNS
cord-355413-ls2nud43	84	19	mediated	mediate	VBN
cord-355413-ls2nud43	84	20	by	by	IN
cord-355413-ls2nud43	84	21	activated	activate	VBN
cord-355413-ls2nud43	84	22	human	human	JJ
cord-355413-ls2nud43	84	23	NK	NK	NNP
cord-355413-ls2nud43	84	24	cells	cell	NNS
cord-355413-ls2nud43	84	25	(	(	-LRB-
cord-355413-ls2nud43	84	26	Saikali	Saikali	NNP
cord-355413-ls2nud43	84	27	et	et	NNP
cord-355413-ls2nud43	84	28	al	al	NNP
cord-355413-ls2nud43	84	29	.	.	NNP
cord-355413-ls2nud43	84	30	,	,	,
cord-355413-ls2nud43	84	31	2007	2007	CD
cord-355413-ls2nud43	84	32	)	)	-RRB-
cord-355413-ls2nud43	84	33	.	.	.
cord-355413-ls2nud43	85	1	These	these	DT
cord-355413-ls2nud43	85	2	results	result	NNS
cord-355413-ls2nud43	85	3	imply	imply	VBP
cord-355413-ls2nud43	85	4	that	that	IN
cord-355413-ls2nud43	85	5	NKG2D	nkg2d	NN
cord-355413-ls2nud43	85	6	-	-	HYPH
cord-355413-ls2nud43	85	7	NKG2D	nkg2d	NN
cord-355413-ls2nud43	85	8	ligand	ligand	NN
cord-355413-ls2nud43	85	9	interactions	interaction	NNS
cord-355413-ls2nud43	85	10	can	can	MD
cord-355413-ls2nud43	85	11	potentially	potentially	RB
cord-355413-ls2nud43	85	12	contribute	contribute	VB
cord-355413-ls2nud43	85	13	to	to	IN
cord-355413-ls2nud43	85	14	cytotoxic	cytotoxic	JJ
cord-355413-ls2nud43	85	15	responses	response	NNS
cord-355413-ls2nud43	85	16	mediated	mediate	VBN
cord-355413-ls2nud43	85	17	by	by	IN
cord-355413-ls2nud43	85	18	activated	activate	VBN
cord-355413-ls2nud43	85	19	immune	immune	JJ
cord-355413-ls2nud43	85	20	effector	effector	NN
cord-355413-ls2nud43	85	21	cells	cell	NNS
cord-355413-ls2nud43	85	22	in	in	IN
cord-355413-ls2nud43	85	23	the	the	DT
cord-355413-ls2nud43	85	24	inflamed	inflamed	JJ
cord-355413-ls2nud43	85	25	CNS	CNS	NNP
cord-355413-ls2nud43	85	26	,	,	,
cord-355413-ls2nud43	85	27	as	as	IN
cord-355413-ls2nud43	85	28	observed	observe	VBN
cord-355413-ls2nud43	85	29	in	in	IN
cord-355413-ls2nud43	85	30	MS	MS	NNP
cord-355413-ls2nud43	85	31	.	.	.
cord-355413-ls2nud43	86	1	In	in	IN
cord-355413-ls2nud43	86	2	the	the	DT
cord-355413-ls2nud43	86	3	context	context	NN
cord-355413-ls2nud43	86	4	of	of	IN
cord-355413-ls2nud43	86	5	tissue	tissue	NN
cord-355413-ls2nud43	86	6	injury	injury	NN
cord-355413-ls2nud43	86	7	that	that	WDT
cord-355413-ls2nud43	86	8	occurs	occur	VBZ
cord-355413-ls2nud43	86	9	in	in	IN
cord-355413-ls2nud43	86	10	MS	MS	NNP
cord-355413-ls2nud43	86	11	,	,	,
cord-355413-ls2nud43	86	12	the	the	DT
cord-355413-ls2nud43	86	13	inflammatory	inflammatory	JJ
cord-355413-ls2nud43	86	14	milieu	milieu	NN
cord-355413-ls2nud43	86	15	in	in	IN
cord-355413-ls2nud43	86	16	MS	MS	NNP
cord-355413-ls2nud43	86	17	lesions	lesion	NNS
cord-355413-ls2nud43	86	18	may	may	MD
cord-355413-ls2nud43	86	19	provide	provide	VB
cord-355413-ls2nud43	86	20	conditions	condition	NNS
cord-355413-ls2nud43	86	21	required	require	VBN
cord-355413-ls2nud43	86	22	for	for	IN
cord-355413-ls2nud43	86	23	NK	NK	NNP
cord-355413-ls2nud43	86	24	cell	cell	NN
cord-355413-ls2nud43	86	25	activation	activation	NN
cord-355413-ls2nud43	86	26	,	,	,
cord-355413-ls2nud43	86	27	raising	raise	VBG
cord-355413-ls2nud43	86	28	the	the	DT
cord-355413-ls2nud43	86	29	possibility	possibility	NN
cord-355413-ls2nud43	86	30	that	that	IN
cord-355413-ls2nud43	86	31	such	such	JJ
cord-355413-ls2nud43	86	32	effector	effector	NN
cord-355413-ls2nud43	86	33	cells	cell	NNS
cord-355413-ls2nud43	86	34	would	would	MD
cord-355413-ls2nud43	86	35	play	play	VB
cord-355413-ls2nud43	86	36	a	a	DT
cord-355413-ls2nud43	86	37	role	role	NN
cord-355413-ls2nud43	86	38	in	in	IN
cord-355413-ls2nud43	86	39	the	the	DT
cord-355413-ls2nud43	86	40	pathogenesis	pathogenesis	NN
cord-355413-ls2nud43	86	41	.	.	.
cord-355413-ls2nud43	87	1	In	in	IN
cord-355413-ls2nud43	87	2	addition	addition	NN
cord-355413-ls2nud43	87	3	to	to	IN
cord-355413-ls2nud43	87	4	direct	direct	VB
cord-355413-ls2nud43	87	5	cytotoxicity	cytotoxicity	NN
cord-355413-ls2nud43	87	6	,	,	,
cord-355413-ls2nud43	87	7	cytokine	cytokine	NN
cord-355413-ls2nud43	87	8	release	release	NN
cord-355413-ls2nud43	87	9	by	by	IN
cord-355413-ls2nud43	87	10	NK	NK	NNP
cord-355413-ls2nud43	87	11	cells	cell	NNS
cord-355413-ls2nud43	87	12	may	may	MD
cord-355413-ls2nud43	87	13	also	also	RB
cord-355413-ls2nud43	87	14	participate	participate	VB
cord-355413-ls2nud43	87	15	in	in	IN
cord-355413-ls2nud43	87	16	tissue	tissue	NN
cord-355413-ls2nud43	87	17	damage	damage	NN
cord-355413-ls2nud43	87	18	as	as	RB
cord-355413-ls2nud43	87	19	well	well	RB
cord-355413-ls2nud43	87	20	as	as	IN
cord-355413-ls2nud43	87	21	in	in	IN
cord-355413-ls2nud43	87	22	regulating	regulate	VBG
cord-355413-ls2nud43	87	23	T	T	NNP
cord-355413-ls2nud43	87	24	cell	cell	NN
cord-355413-ls2nud43	87	25	immune	immune	JJ
cord-355413-ls2nud43	87	26	responses	response	NNS
cord-355413-ls2nud43	87	27	.	.	.
cord-355413-ls2nud43	88	1	Interferon	interferon	NN
cord-355413-ls2nud43	88	2	-	-	HYPH
cord-355413-ls2nud43	88	3	gamma	gamma	NN
cord-355413-ls2nud43	88	4	(	(	-LRB-
cord-355413-ls2nud43	88	5	IFN-	IFN-	NNP
cord-355413-ls2nud43	88	6	)	)	-RRB-
cord-355413-ls2nud43	88	7	is	be	VBZ
cord-355413-ls2nud43	88	8	a	a	DT
cord-355413-ls2nud43	88	9	pleiotropic	pleiotropic	JJ
cord-355413-ls2nud43	88	10	cytokine	cytokine	NN
cord-355413-ls2nud43	88	11	produced	produce	VBN
cord-355413-ls2nud43	88	12	by	by	IN
cord-355413-ls2nud43	88	13	T	T	NNP
cord-355413-ls2nud43	88	14	cells	cell	NNS
cord-355413-ls2nud43	88	15	and	and	CC
cord-355413-ls2nud43	88	16	NK	NK	NNP
cord-355413-ls2nud43	88	17	cells	cell	NNS
cord-355413-ls2nud43	88	18	that	that	WDT
cord-355413-ls2nud43	88	19	has	have	VBZ
cord-355413-ls2nud43	88	20	been	be	VBN
cord-355413-ls2nud43	88	21	implicated	implicate	VBN
cord-355413-ls2nud43	88	22	as	as	IN
cord-355413-ls2nud43	88	23	a	a	DT
cord-355413-ls2nud43	88	24	deleterious	deleterious	JJ
cord-355413-ls2nud43	88	25	factor	factor	NN
cord-355413-ls2nud43	88	26	in	in	IN
cord-355413-ls2nud43	88	27	MS	MS	NNP
cord-355413-ls2nud43	88	28	,	,	,
cord-355413-ls2nud43	88	29	the	the	DT
cord-355413-ls2nud43	88	30	immune	immune	NN
cord-355413-ls2nud43	88	31	-	-	HYPH
cord-355413-ls2nud43	88	32	mediated	mediate	VBN
cord-355413-ls2nud43	88	33	demyelinating	demyelinating	JJ
cord-355413-ls2nud43	88	34	disorder	disorder	NN
cord-355413-ls2nud43	88	35	.	.	.
cord-355413-ls2nud43	89	1	In	in	IN
cord-355413-ls2nud43	89	2	vitro	vitro	FW
cord-355413-ls2nud43	89	3	,	,	,
cord-355413-ls2nud43	89	4	purified	purify	VBN
cord-355413-ls2nud43	89	5	developing	develop	VBG
cord-355413-ls2nud43	89	6	and	and	CC
cord-355413-ls2nud43	89	7	mature	mature	VB
cord-355413-ls2nud43	89	8	oligodendrocytes	oligodendrocyte	NNS
cord-355413-ls2nud43	89	9	die	die	VBP
cord-355413-ls2nud43	89	10	in	in	IN
cord-355413-ls2nud43	89	11	the	the	DT
cord-355413-ls2nud43	89	12	presence	presence	NN
cord-355413-ls2nud43	89	13	of	of	IN
cord-355413-ls2nud43	89	14	IFN-	ifn-	XX
cord-355413-ls2nud43	89	15	by	by	IN
cord-355413-ls2nud43	89	16	apoptosis	apoptosis	NN
cord-355413-ls2nud43	89	17	and	and	CC
cord-355413-ls2nud43	89	18	necrosis	necrosis	NN
cord-355413-ls2nud43	89	19	,	,	,
cord-355413-ls2nud43	89	20	respectively	respectively	RB
cord-355413-ls2nud43	89	21	.	.	.
cord-355413-ls2nud43	90	1	Transgenic	transgenic	JJ
cord-355413-ls2nud43	90	2	expression	expression	NN
cord-355413-ls2nud43	90	3	of	of	IN
cord-355413-ls2nud43	90	4	PLP	PLP	NNP
cord-355413-ls2nud43	90	5	/	/	SYM
cord-355413-ls2nud43	90	6	SOCS1	SOCS1	NNP
cord-355413-ls2nud43	91	1	(	(	-LRB-
cord-355413-ls2nud43	91	2	proteolipid	proteolipid	NNP
cord-355413-ls2nud43	91	3	protein	protein	NNP
cord-355413-ls2nud43	91	4	regulating	regulate	VBG
cord-355413-ls2nud43	91	5	suppressor	suppressor	NN
cord-355413-ls2nud43	91	6	of	of	IN
cord-355413-ls2nud43	91	7	cytokine	cytokine	NN
cord-355413-ls2nud43	91	8	signalling	signal	VBG
cord-355413-ls2nud43	91	9	1	1	CD
cord-355413-ls2nud43	91	10	)	)	-RRB-
cord-355413-ls2nud43	91	11	,	,	,
cord-355413-ls2nud43	91	12	brings	bring	VBZ
cord-355413-ls2nud43	91	13	about	about	IN
cord-355413-ls2nud43	91	14	diminished	diminish	VBN
cord-355413-ls2nud43	91	15	oligodendrocyte	oligodendrocyte	IN
cord-355413-ls2nud43	91	16	responsiveness	responsiveness	NN
cord-355413-ls2nud43	91	17	to	to	IN
cord-355413-ls2nud43	91	18	IFN-	IFN-	NNP
cord-355413-ls2nud43	91	19	attributable	attributable	JJ
cord-355413-ls2nud43	91	20	to	to	IN
cord-355413-ls2nud43	91	21	the	the	DT
cord-355413-ls2nud43	91	22	targeted	target	VBN
cord-355413-ls2nud43	91	23	expression	expression	NN
cord-355413-ls2nud43	91	24	of	of	IN
cord-355413-ls2nud43	91	25	SOCS1	socs1	NN
cord-355413-ls2nud43	91	26	in	in	IN
cord-355413-ls2nud43	91	27	these	these	DT
cord-355413-ls2nud43	91	28	cells	cell	NNS
cord-355413-ls2nud43	91	29	(	(	-LRB-
cord-355413-ls2nud43	91	30	Balabanov	Balabanov	NNP
cord-355413-ls2nud43	91	31	et	et	NNP
cord-355413-ls2nud43	91	32	al	al	NNP
cord-355413-ls2nud43	91	33	.	.	NNP
cord-355413-ls2nud43	91	34	,	,	,
cord-355413-ls2nud43	91	35	2006	2006	CD
cord-355413-ls2nud43	91	36	)	)	-RRB-
cord-355413-ls2nud43	91	37	.	.	.
cord-355413-ls2nud43	92	1	Consequently	consequently	RB
cord-355413-ls2nud43	92	2	,	,	,
cord-355413-ls2nud43	92	3	oligodendrocytes	oligodendrocyte	NNS
cord-355413-ls2nud43	92	4	in	in	IN
cord-355413-ls2nud43	92	5	the	the	DT
cord-355413-ls2nud43	92	6	PLP	PLP	NNP
cord-355413-ls2nud43	92	7	/	/	SYM
cord-355413-ls2nud43	92	8	SOCS1	socs1	NN
cord-355413-ls2nud43	92	9	transgenic	transgenic	JJ
cord-355413-ls2nud43	92	10	mice	mouse	NNS
cord-355413-ls2nud43	92	11	are	be	VBP
cord-355413-ls2nud43	92	12	protected	protect	VBN
cord-355413-ls2nud43	92	13	against	against	IN
cord-355413-ls2nud43	92	14	the	the	DT
cord-355413-ls2nud43	92	15	injurious	injurious	JJ
cord-355413-ls2nud43	92	16	effect	effect	NN
cord-355413-ls2nud43	92	17	of	of	IN
cord-355413-ls2nud43	92	18	IFN-.	ifn-.	XX
cord-355413-ls2nud43	93	1	Although	although	IN
cord-355413-ls2nud43	93	2	both	both	DT
cord-355413-ls2nud43	93	3	NK	NK	NNP
cord-355413-ls2nud43	93	4	cells	cell	NNS
cord-355413-ls2nud43	93	5	and	and	CC
cord-355413-ls2nud43	93	6	T	t	NN
cord-355413-ls2nud43	93	7	cells	cell	NNS
cord-355413-ls2nud43	93	8	produce	produce	VBP
cord-355413-ls2nud43	93	9	IFN-	ifn-	XX
cord-355413-ls2nud43	93	10	,	,	,
cord-355413-ls2nud43	93	11	NK	NK	NNP
cord-355413-ls2nud43	93	12	cells	cell	NNS
cord-355413-ls2nud43	93	13	are	be	VBP
cord-355413-ls2nud43	93	14	the	the	DT
cord-355413-ls2nud43	93	15	principal	principal	JJ
cord-355413-ls2nud43	93	16	sources	source	NNS
cord-355413-ls2nud43	93	17	of	of	IN
cord-355413-ls2nud43	93	18	early	early	JJ
cord-355413-ls2nud43	93	19	IFN-	ifn-	DT
cord-355413-ls2nud43	93	20	production	production	NN
cord-355413-ls2nud43	93	21	prior	prior	RB
cord-355413-ls2nud43	93	22	to	to	IN
cord-355413-ls2nud43	93	23	T	T	NNP
cord-355413-ls2nud43	93	24	cell	cell	NN
cord-355413-ls2nud43	93	25	activation	activation	NN
cord-355413-ls2nud43	93	26	.	.	.
cord-355413-ls2nud43	94	1	This	this	DT
cord-355413-ls2nud43	94	2	time	time	NN
cord-355413-ls2nud43	94	3	kinetic	kinetic	JJ
cord-355413-ls2nud43	94	4	might	may	MD
cord-355413-ls2nud43	94	5	be	be	VB
cord-355413-ls2nud43	94	6	particularly	particularly	RB
cord-355413-ls2nud43	94	7	relevant	relevant	JJ
cord-355413-ls2nud43	94	8	for	for	IN
cord-355413-ls2nud43	94	9	early	early	JJ
cord-355413-ls2nud43	94	10	oligodendrocyte	oligodendrocyte	VBN
cord-355413-ls2nud43	94	11	damage	damage	NN
cord-355413-ls2nud43	94	12	during	during	IN
cord-355413-ls2nud43	94	13	inflammation	inflammation	NN
cord-355413-ls2nud43	94	14	.	.	.
cord-355413-ls2nud43	95	1	Efficient	efficient	JJ
cord-355413-ls2nud43	95	2	early	early	JJ
cord-355413-ls2nud43	95	3	control	control	NN
cord-355413-ls2nud43	95	4	of	of	IN
cord-355413-ls2nud43	95	5	viral	viral	JJ
cord-355413-ls2nud43	95	6	infections	infection	NNS
cord-355413-ls2nud43	95	7	is	be	VBZ
cord-355413-ls2nud43	95	8	determined	determine	VBN
cord-355413-ls2nud43	95	9	by	by	IN
cord-355413-ls2nud43	95	10	viral	viral	JJ
cord-355413-ls2nud43	95	11	tissue	tissue	NN
cord-355413-ls2nud43	95	12	tropism	tropism	NN
cord-355413-ls2nud43	95	13	and	and	CC
cord-355413-ls2nud43	95	14	rate	rate	NN
cord-355413-ls2nud43	95	15	of	of	IN
cord-355413-ls2nud43	95	16	replication	replication	NN
cord-355413-ls2nud43	95	17	as	as	RB
cord-355413-ls2nud43	95	18	well	well	RB
cord-355413-ls2nud43	95	19	as	as	IN
cord-355413-ls2nud43	95	20	the	the	DT
cord-355413-ls2nud43	95	21	host	host	NN
cord-355413-ls2nud43	95	22	's	's	POS
cord-355413-ls2nud43	95	23	ability	ability	NN
cord-355413-ls2nud43	95	24	to	to	TO
cord-355413-ls2nud43	95	25	mount	mount	VB
cord-355413-ls2nud43	95	26	an	an	DT
cord-355413-ls2nud43	95	27	effective	effective	JJ
cord-355413-ls2nud43	95	28	immune	immune	JJ
cord-355413-ls2nud43	95	29	response	response	NN
cord-355413-ls2nud43	95	30	.	.	.
cord-355413-ls2nud43	96	1	Cellular	cellular	JJ
cord-355413-ls2nud43	96	2	cytotoxicity	cytotoxicity	NN
cord-355413-ls2nud43	96	3	,	,	,
cord-355413-ls2nud43	96	4	in	in	IN
cord-355413-ls2nud43	96	5	particular	particular	JJ
cord-355413-ls2nud43	96	6	,	,	,
cord-355413-ls2nud43	96	7	that	that	DT
cord-355413-ls2nud43	96	8	of	of	IN
cord-355413-ls2nud43	96	9	NK	NK	NNP
cord-355413-ls2nud43	96	10	cells	cell	NNS
cord-355413-ls2nud43	96	11	and	and	CC
cord-355413-ls2nud43	96	12	cytotoxic	cytotoxic	JJ
cord-355413-ls2nud43	96	13	T	t	NN
cord-355413-ls2nud43	96	14	cells	cell	NNS
cord-355413-ls2nud43	96	15	,	,	,
cord-355413-ls2nud43	96	16	is	be	VBZ
cord-355413-ls2nud43	96	17	central	central	JJ
cord-355413-ls2nud43	96	18	to	to	IN
cord-355413-ls2nud43	96	19	the	the	DT
cord-355413-ls2nud43	96	20	early	early	JJ
cord-355413-ls2nud43	96	21	antiviral	antiviral	JJ
cord-355413-ls2nud43	96	22	immune	immune	JJ
cord-355413-ls2nud43	96	23	response	response	NN
cord-355413-ls2nud43	96	24	.	.	.
cord-355413-ls2nud43	97	1	Table	table	NN
cord-355413-ls2nud43	97	2	28	28	CD
cord-355413-ls2nud43	97	3	.1	.1	NN
cord-355413-ls2nud43	97	4	illustrates	illustrate	VBZ
cord-355413-ls2nud43	97	5	several	several	JJ
cord-355413-ls2nud43	97	6	immunedeficient	immunedeficient	JJ
cord-355413-ls2nud43	97	7	conditions	condition	NNS
cord-355413-ls2nud43	97	8	in	in	IN
cord-355413-ls2nud43	97	9	humans	human	NNS
cord-355413-ls2nud43	97	10	,	,	,
cord-355413-ls2nud43	97	11	which	which	WDT
cord-355413-ls2nud43	97	12	stem	stem	VBP
cord-355413-ls2nud43	97	13	from	from	IN
cord-355413-ls2nud43	97	14	mutations	mutation	NNS
cord-355413-ls2nud43	97	15	affecting	affect	VBG
cord-355413-ls2nud43	97	16	NK	NK	NNP
cord-355413-ls2nud43	97	17	cells	cell	NNS
cord-355413-ls2nud43	97	18	(	(	-LRB-
cord-355413-ls2nud43	97	19	Biron	Biron	NNP
cord-355413-ls2nud43	97	20	et	et	NNP
cord-355413-ls2nud43	97	21	al	al	NNP
cord-355413-ls2nud43	97	22	.	.	NNP
cord-355413-ls2nud43	97	23	,	,	,
cord-355413-ls2nud43	97	24	1989	1989	CD
cord-355413-ls2nud43	97	25	;	;	:
cord-355413-ls2nud43	98	1	Gilmour	Gilmour	NNP
cord-355413-ls2nud43	98	2	et	et	NNP
cord-355413-ls2nud43	98	3	al	al	NNP
cord-355413-ls2nud43	98	4	.	.	NNP
cord-355413-ls2nud43	98	5	,	,	,
cord-355413-ls2nud43	98	6	2001	2001	CD
cord-355413-ls2nud43	99	1	;	;	:
cord-355413-ls2nud43	99	2	Markel	Markel	NNP
cord-355413-ls2nud43	99	3	et	et	NNP
cord-355413-ls2nud43	99	4	al	al	NNP
cord-355413-ls2nud43	99	5	.	.	NNP
cord-355413-ls2nud43	99	6	,	,	,
cord-355413-ls2nud43	99	7	2004	2004	CD
cord-355413-ls2nud43	99	8	;	;	:
cord-355413-ls2nud43	99	9	Moins	Moins	NNP
cord-355413-ls2nud43	99	10	-	-	HYPH
cord-355413-ls2nud43	99	11	Teisserenc	Teisserenc	NNP
cord-355413-ls2nud43	99	12	et	et	NNP
cord-355413-ls2nud43	99	13	al	al	NNP
cord-355413-ls2nud43	99	14	.	.	NNP
cord-355413-ls2nud43	99	15	,	,	,
cord-355413-ls2nud43	99	16	1999	1999	CD
cord-355413-ls2nud43	99	17	)	)	-RRB-
cord-355413-ls2nud43	99	18	.	.	.
cord-355413-ls2nud43	100	1	A	a	DT
cord-355413-ls2nud43	100	2	number	number	NN
cord-355413-ls2nud43	100	3	of	of	IN
cord-355413-ls2nud43	100	4	studies	study	NNS
cord-355413-ls2nud43	100	5	have	have	VBP
cord-355413-ls2nud43	100	6	demonstrated	demonstrate	VBN
cord-355413-ls2nud43	100	7	the	the	DT
cord-355413-ls2nud43	100	8	recruitment	recruitment	NN
cord-355413-ls2nud43	100	9	and	and	CC
cord-355413-ls2nud43	100	10	activation	activation	NN
cord-355413-ls2nud43	100	11	of	of	IN
cord-355413-ls2nud43	100	12	NK	NK	NNP
cord-355413-ls2nud43	100	13	cells	cell	NNS
cord-355413-ls2nud43	100	14	following	follow	VBG
cord-355413-ls2nud43	100	15	infection	infection	NN
cord-355413-ls2nud43	100	16	with	with	IN
cord-355413-ls2nud43	100	17	a	a	DT
cord-355413-ls2nud43	100	18	wide	wide	JJ
cord-355413-ls2nud43	100	19	range	range	NN
cord-355413-ls2nud43	100	20	of	of	IN
cord-355413-ls2nud43	100	21	viruses	virus	NNS
cord-355413-ls2nud43	100	22	.	.	.
cord-355413-ls2nud43	101	1	However	however	RB
cord-355413-ls2nud43	101	2	,	,	,
cord-355413-ls2nud43	101	3	not	not	RB
cord-355413-ls2nud43	101	4	all	all	DT
cord-355413-ls2nud43	101	5	viral	viral	JJ
cord-355413-ls2nud43	101	6	infections	infection	NNS
cord-355413-ls2nud43	102	1	P	p	NN
cord-355413-ls2nud43	102	2	A	a	NN
cord-355413-ls2nud43	103	1	R	R	NNP
cord-355413-ls2nud43	103	2	T	t	NN
cord-355413-ls2nud43	104	1	I	-PRON-	PRP
cord-355413-ls2nud43	105	1	I	-PRON-	PRP
cord-355413-ls2nud43	106	1	I	-PRON-	PRP
cord-355413-ls2nud43	106	2	are	be	VBP
cord-355413-ls2nud43	106	3	susceptible	susceptible	JJ
cord-355413-ls2nud43	106	4	to	to	IN
cord-355413-ls2nud43	106	5	NK	nk	NN
cord-355413-ls2nud43	106	6	-	-	HYPH
cord-355413-ls2nud43	106	7	mediated	mediate	VBN
cord-355413-ls2nud43	106	8	clearance	clearance	NN
cord-355413-ls2nud43	106	9	,	,	,
cord-355413-ls2nud43	106	10	and	and	CC
cord-355413-ls2nud43	106	11	susceptibility	susceptibility	NN
cord-355413-ls2nud43	106	12	depends	depend	VBZ
cord-355413-ls2nud43	106	13	upon	upon	IN
cord-355413-ls2nud43	106	14	the	the	DT
cord-355413-ls2nud43	106	15	effector	effector	NN
cord-355413-ls2nud43	106	16	mechanisms	mechanism	NNS
cord-355413-ls2nud43	106	17	induced	induce	VBN
cord-355413-ls2nud43	106	18	.	.	.
cord-355413-ls2nud43	107	1	For	for	IN
cord-355413-ls2nud43	107	2	example	example	NN
cord-355413-ls2nud43	107	3	,	,	,
cord-355413-ls2nud43	107	4	the	the	DT
cord-355413-ls2nud43	107	5	induction	induction	NN
cord-355413-ls2nud43	107	6	of	of	IN
cord-355413-ls2nud43	107	7	both	both	CC
cord-355413-ls2nud43	107	8	cytotoxicity	cytotoxicity	NN
cord-355413-ls2nud43	107	9	and	and	CC
cord-355413-ls2nud43	107	10	IFN-	ifn-	DT
cord-355413-ls2nud43	107	11	production	production	NN
cord-355413-ls2nud43	107	12	by	by	IN
cord-355413-ls2nud43	107	13	NK	NK	NNP
cord-355413-ls2nud43	107	14	cells	cell	NNS
cord-355413-ls2nud43	107	15	following	follow	VBG
cord-355413-ls2nud43	107	16	murine	murine	JJ
cord-355413-ls2nud43	107	17	cytomegalovirus	cytomegalovirus	NN
cord-355413-ls2nud43	107	18	(	(	-LRB-
cord-355413-ls2nud43	107	19	CMV	CMV	NNP
cord-355413-ls2nud43	107	20	)	)	-RRB-
cord-355413-ls2nud43	107	21	and	and	CC
cord-355413-ls2nud43	107	22	influenza	influenza	NN
cord-355413-ls2nud43	107	23	virus	virus	NN
cord-355413-ls2nud43	107	24	infection	infection	NN
cord-355413-ls2nud43	107	25	results	result	VBZ
cord-355413-ls2nud43	107	26	in	in	IN
cord-355413-ls2nud43	107	27	reduced	reduce	VBN
cord-355413-ls2nud43	107	28	virally	virally	RB
cord-355413-ls2nud43	107	29	induced	induce	VBN
cord-355413-ls2nud43	107	30	disease	disease	NN
cord-355413-ls2nud43	107	31	and	and	CC
cord-355413-ls2nud43	107	32	enhanced	enhanced	JJ
cord-355413-ls2nud43	107	33	survival	survival	NN
cord-355413-ls2nud43	107	34	.	.	.
cord-355413-ls2nud43	108	1	Along	along	IN
cord-355413-ls2nud43	108	2	the	the	DT
cord-355413-ls2nud43	108	3	same	same	JJ
cord-355413-ls2nud43	108	4	time	time	NN
cord-355413-ls2nud43	108	5	,	,	,
cord-355413-ls2nud43	108	6	deficient	deficient	JJ
cord-355413-ls2nud43	108	7	IFN-	ifn-	CD
cord-355413-ls2nud43	108	8	production	production	NN
cord-355413-ls2nud43	108	9	by	by	IN
cord-355413-ls2nud43	108	10	NK	NK	NNP
cord-355413-ls2nud43	108	11	cells	cell	NNS
cord-355413-ls2nud43	108	12	correlates	correlate	VBZ
cord-355413-ls2nud43	108	13	with	with	IN
cord-355413-ls2nud43	108	14	the	the	DT
cord-355413-ls2nud43	108	15	absence	absence	NN
cord-355413-ls2nud43	108	16	of	of	IN
cord-355413-ls2nud43	108	17	an	an	DT
cord-355413-ls2nud43	108	18	effective	effective	JJ
cord-355413-ls2nud43	108	19	innate	innate	JJ
cord-355413-ls2nud43	108	20	response	response	NN
cord-355413-ls2nud43	108	21	to	to	IN
cord-355413-ls2nud43	108	22	lymphocytic	lymphocytic	JJ
cord-355413-ls2nud43	108	23	choriomeningitis	choriomeningitis	NNP
cord-355413-ls2nud43	108	24	virus	virus	NN
cord-355413-ls2nud43	108	25	infection	infection	NN
cord-355413-ls2nud43	108	26	.	.	.
cord-355413-ls2nud43	109	1	Moreover	moreover	RB
cord-355413-ls2nud43	109	2	,	,	,
cord-355413-ls2nud43	109	3	the	the	DT
cord-355413-ls2nud43	109	4	organs	organ	NNS
cord-355413-ls2nud43	109	5	targeted	target	VBN
cord-355413-ls2nud43	109	6	by	by	IN
cord-355413-ls2nud43	109	7	viral	viral	JJ
cord-355413-ls2nud43	109	8	infection	infection	NN
cord-355413-ls2nud43	109	9	can	can	MD
cord-355413-ls2nud43	109	10	also	also	RB
cord-355413-ls2nud43	109	11	influence	influence	VB
cord-355413-ls2nud43	109	12	the	the	DT
cord-355413-ls2nud43	109	13	participation	participation	NN
cord-355413-ls2nud43	109	14	of	of	IN
cord-355413-ls2nud43	109	15	NK	NK	NNP
cord-355413-ls2nud43	109	16	cells	cell	NNS
cord-355413-ls2nud43	109	17	.	.	.
cord-355413-ls2nud43	110	1	Indeed	indeed	RB
cord-355413-ls2nud43	110	2	,	,	,
cord-355413-ls2nud43	110	3	it	-PRON-	PRP
cord-355413-ls2nud43	110	4	has	have	VBZ
cord-355413-ls2nud43	110	5	been	be	VBN
cord-355413-ls2nud43	110	6	shown	show	VBN
cord-355413-ls2nud43	110	7	that	that	IN
cord-355413-ls2nud43	110	8	the	the	DT
cord-355413-ls2nud43	110	9	NK	NK	NNP
cord-355413-ls2nud43	110	10	response	response	NN
cord-355413-ls2nud43	110	11	to	to	IN
cord-355413-ls2nud43	110	12	murine	murine	JJ
cord-355413-ls2nud43	110	13	CMV	CMV	NNP
cord-355413-ls2nud43	110	14	is	be	VBZ
cord-355413-ls2nud43	110	15	perforin	perforin	NN
cord-355413-ls2nud43	110	16	-	-	HYPH
cord-355413-ls2nud43	110	17	dependent	dependent	JJ
cord-355413-ls2nud43	110	18	within	within	IN
cord-355413-ls2nud43	110	19	the	the	DT
cord-355413-ls2nud43	110	20	spleen	spleen	NN
cord-355413-ls2nud43	110	21	,	,	,
cord-355413-ls2nud43	110	22	whereas	whereas	IN
cord-355413-ls2nud43	110	23	production	production	NN
cord-355413-ls2nud43	110	24	of	of	IN
cord-355413-ls2nud43	110	25	IFN-	IFN-	NNP
cord-355413-ls2nud43	110	26	is	be	VBZ
cord-355413-ls2nud43	110	27	required	require	VBN
cord-355413-ls2nud43	110	28	for	for	IN
cord-355413-ls2nud43	110	29	viral	viral	JJ
cord-355413-ls2nud43	110	30	clearance	clearance	NN
cord-355413-ls2nud43	110	31	from	from	IN
cord-355413-ls2nud43	110	32	the	the	DT
cord-355413-ls2nud43	110	33	liver	liver	NN
cord-355413-ls2nud43	110	34	.	.	.
cord-355413-ls2nud43	111	1	These	these	DT
cord-355413-ls2nud43	111	2	results	result	NNS
cord-355413-ls2nud43	111	3	indicate	indicate	VBP
cord-355413-ls2nud43	111	4	that	that	IN
cord-355413-ls2nud43	111	5	the	the	DT
cord-355413-ls2nud43	111	6	importance	importance	NN
cord-355413-ls2nud43	111	7	of	of	IN
cord-355413-ls2nud43	111	8	the	the	DT
cord-355413-ls2nud43	111	9	NK	NK	NNP
cord-355413-ls2nud43	111	10	cell	cell	NN
cord-355413-ls2nud43	111	11	response	response	NN
cord-355413-ls2nud43	111	12	to	to	IN
cord-355413-ls2nud43	111	13	viral	viral	JJ
cord-355413-ls2nud43	111	14	infection	infection	NN
cord-355413-ls2nud43	111	15	can	can	MD
cord-355413-ls2nud43	111	16	depend	depend	VB
cord-355413-ls2nud43	111	17	upon	upon	IN
cord-355413-ls2nud43	111	18	multiple	multiple	JJ
cord-355413-ls2nud43	111	19	factors	factor	NNS
cord-355413-ls2nud43	111	20	,	,	,
cord-355413-ls2nud43	111	21	including	include	VBG
cord-355413-ls2nud43	111	22	the	the	DT
cord-355413-ls2nud43	111	23	tissue	tissue	NN
cord-355413-ls2nud43	111	24	infected	infect	VBN
cord-355413-ls2nud43	111	25	,	,	,
cord-355413-ls2nud43	111	26	as	as	RB
cord-355413-ls2nud43	111	27	well	well	RB
cord-355413-ls2nud43	111	28	as	as	IN
cord-355413-ls2nud43	111	29	the	the	DT
cord-355413-ls2nud43	111	30	effector	effector	NN
cord-355413-ls2nud43	111	31	mechanisms	mechanism	NNS
cord-355413-ls2nud43	111	32	induced	induce	VBN
cord-355413-ls2nud43	111	33	.	.	.
cord-355413-ls2nud43	112	1	Although	although	IN
cord-355413-ls2nud43	112	2	a	a	DT
cord-355413-ls2nud43	112	3	number	number	NN
cord-355413-ls2nud43	112	4	of	of	IN
cord-355413-ls2nud43	112	5	studies	study	NNS
cord-355413-ls2nud43	112	6	have	have	VBP
cord-355413-ls2nud43	112	7	documented	document	VBN
cord-355413-ls2nud43	112	8	the	the	DT
cord-355413-ls2nud43	112	9	possible	possible	JJ
cord-355413-ls2nud43	112	10	role	role	NN
cord-355413-ls2nud43	112	11	for	for	IN
cord-355413-ls2nud43	112	12	NK	NK	NNP
cord-355413-ls2nud43	112	13	cells	cell	NNS
cord-355413-ls2nud43	112	14	in	in	IN
cord-355413-ls2nud43	112	15	controlling	control	VBG
cord-355413-ls2nud43	112	16	CNS	CNS	NNP
cord-355413-ls2nud43	112	17	infection	infection	NN
cord-355413-ls2nud43	112	18	with	with	IN
cord-355413-ls2nud43	112	19	CMV	CMV	NNP
cord-355413-ls2nud43	112	20	,	,	,
cord-355413-ls2nud43	112	21	influenza	influenza	NN
cord-355413-ls2nud43	112	22	and	and	CC
cord-355413-ls2nud43	112	23	other	other	JJ
cord-355413-ls2nud43	112	24	viruses	virus	NNS
cord-355413-ls2nud43	112	25	,	,	,
cord-355413-ls2nud43	112	26	the	the	DT
cord-355413-ls2nud43	112	27	following	follow	VBG
cord-355413-ls2nud43	112	28	studies	study	NNS
cord-355413-ls2nud43	112	29	provide	provide	VBP
cord-355413-ls2nud43	112	30	relatively	relatively	RB
cord-355413-ls2nud43	112	31	direct	direct	JJ
cord-355413-ls2nud43	112	32	evidence	evidence	NN
cord-355413-ls2nud43	112	33	for	for	IN
cord-355413-ls2nud43	112	34	the	the	DT
cord-355413-ls2nud43	112	35	importance	importance	NN
cord-355413-ls2nud43	112	36	of	of	IN
cord-355413-ls2nud43	112	37	NK	NK	NNP
cord-355413-ls2nud43	112	38	cells	cell	NNS
cord-355413-ls2nud43	112	39	during	during	IN
cord-355413-ls2nud43	112	40	CNS	CNS	NNP
cord-355413-ls2nud43	112	41	viral	viral	JJ
cord-355413-ls2nud43	112	42	infection	infection	NN
cord-355413-ls2nud43	112	43	:	:	:
cord-355413-ls2nud43	112	44	Theiler	Theiler	NNP
cord-355413-ls2nud43	112	45	's	's	POS
cord-355413-ls2nud43	112	46	murine	murine	JJ
cord-355413-ls2nud43	112	47	encephalomyelitis	encephalomyelitis	NN
cord-355413-ls2nud43	112	48	virus	virus	NN
cord-355413-ls2nud43	112	49	(	(	-LRB-
cord-355413-ls2nud43	112	50	TMEV	TMEV	NNP
cord-355413-ls2nud43	112	51	)	)	-RRB-
cord-355413-ls2nud43	112	52	is	be	VBZ
cord-355413-ls2nud43	112	53	a	a	DT
cord-355413-ls2nud43	112	54	picornavirus	picornavirus	NN
cord-355413-ls2nud43	112	55	.	.	.
cord-355413-ls2nud43	113	1	Infection	infection	NN
cord-355413-ls2nud43	113	2	of	of	IN
cord-355413-ls2nud43	113	3	susceptible	susceptible	JJ
cord-355413-ls2nud43	113	4	mice	mouse	NNS
cord-355413-ls2nud43	113	5	(	(	-LRB-
cord-355413-ls2nud43	113	6	SJL	SJL	NNP
cord-355413-ls2nud43	113	7	)	)	-RRB-
cord-355413-ls2nud43	113	8	with	with	IN
cord-355413-ls2nud43	113	9	TMEV	TMEV	NNP
cord-355413-ls2nud43	113	10	causes	cause	VBZ
cord-355413-ls2nud43	113	11	a	a	DT
cord-355413-ls2nud43	113	12	biphasic	biphasic	JJ
cord-355413-ls2nud43	113	13	disease	disease	NN
cord-355413-ls2nud43	113	14	characterized	characterize	VBN
cord-355413-ls2nud43	113	15	by	by	IN
cord-355413-ls2nud43	113	16	grey	grey	JJ
cord-355413-ls2nud43	113	17	matter	matter	NN
cord-355413-ls2nud43	113	18	inflammation	inflammation	NN
cord-355413-ls2nud43	113	19	followed	follow	VBN
cord-355413-ls2nud43	113	20	by	by	IN
cord-355413-ls2nud43	113	21	late	late	JJ
cord-355413-ls2nud43	113	22	chronic	chronic	JJ
cord-355413-ls2nud43	113	23	demyelination	demyelination	NN
cord-355413-ls2nud43	113	24	(	(	-LRB-
cord-355413-ls2nud43	113	25	Roos	Roos	NNP
cord-355413-ls2nud43	113	26	and	and	CC
cord-355413-ls2nud43	113	27	Wollmann	Wollmann	NNP
cord-355413-ls2nud43	113	28	,	,	,
cord-355413-ls2nud43	113	29	1984	1984	CD
cord-355413-ls2nud43	113	30	;	;	.
cord-355413-ls2nud43	114	1	Rosenthal	Rosenthal	NNP
cord-355413-ls2nud43	114	2	et	et	NNP
cord-355413-ls2nud43	114	3	al	al	NNP
cord-355413-ls2nud43	114	4	.	.	NNP
cord-355413-ls2nud43	114	5	,	,	,
cord-355413-ls2nud43	114	6	1986	1986	CD
cord-355413-ls2nud43	114	7	)	)	-RRB-
cord-355413-ls2nud43	114	8	.	.	.
cord-355413-ls2nud43	115	1	After	after	IN
cord-355413-ls2nud43	115	2	inoculation	inoculation	NN
cord-355413-ls2nud43	115	3	,	,	,
cord-355413-ls2nud43	115	4	CNS	CNS	NNP
cord-355413-ls2nud43	115	5	TMEV	TMEV	NNP
cord-355413-ls2nud43	115	6	titres	titre	NNS
cord-355413-ls2nud43	115	7	were	be	VBD
cord-355413-ls2nud43	115	8	higher	high	JJR
cord-355413-ls2nud43	115	9	in	in	IN
cord-355413-ls2nud43	115	10	SJL	SJL	NNP
cord-355413-ls2nud43	115	11	mice	mouse	NNS
cord-355413-ls2nud43	115	12	compared	compare	VBN
cord-355413-ls2nud43	115	13	with	with	IN
cord-355413-ls2nud43	115	14	C57BL/10	C57BL/10	NNP
cord-355413-ls2nud43	115	15	mice	mouse	NNS
cord-355413-ls2nud43	115	16	,	,	,
cord-355413-ls2nud43	115	17	correlating	correlate	VBG
cord-355413-ls2nud43	115	18	with	with	IN
cord-355413-ls2nud43	115	19	a	a	DT
cord-355413-ls2nud43	115	20	50	50	CD
cord-355413-ls2nud43	115	21	%	%	NN
cord-355413-ls2nud43	115	22	lower	low	JJR
cord-355413-ls2nud43	115	23	NK	NK	NNP
cord-355413-ls2nud43	115	24	cell	cell	NN
cord-355413-ls2nud43	115	25	activity	activity	NN
cord-355413-ls2nud43	115	26	in	in	IN
cord-355413-ls2nud43	115	27	the	the	DT
cord-355413-ls2nud43	115	28	SJL	SJL	NNP
cord-355413-ls2nud43	115	29	mice	mouse	NNS
cord-355413-ls2nud43	115	30	than	than	IN
cord-355413-ls2nud43	115	31	in	in	IN
cord-355413-ls2nud43	115	32	the	the	DT
cord-355413-ls2nud43	115	33	C57BL/10	C57BL/10	NNP
cord-355413-ls2nud43	115	34	mice	mouse	NNS
cord-355413-ls2nud43	115	35	(	(	-LRB-
cord-355413-ls2nud43	115	36	Paya	Paya	NNP
cord-355413-ls2nud43	115	37	et	et	NNP
cord-355413-ls2nud43	115	38	al	al	NNP
cord-355413-ls2nud43	115	39	.	.	NNP
cord-355413-ls2nud43	115	40	,	,	,
cord-355413-ls2nud43	115	41	1989	1989	CD
cord-355413-ls2nud43	115	42	)	)	-RRB-
cord-355413-ls2nud43	115	43	.	.	.
cord-355413-ls2nud43	116	1	Clinically	clinically	RB
cord-355413-ls2nud43	116	2	,	,	,
cord-355413-ls2nud43	116	3	SJL	SJL	NNP
cord-355413-ls2nud43	116	4	mice	mouse	NNS
cord-355413-ls2nud43	116	5	are	be	VBP
cord-355413-ls2nud43	116	6	much	much	RB
cord-355413-ls2nud43	116	7	more	more	RBR
cord-355413-ls2nud43	116	8	susceptible	susceptible	JJ
cord-355413-ls2nud43	116	9	than	than	IN
cord-355413-ls2nud43	116	10	C57BL/10	c57bl/10	JJ
cord-355413-ls2nud43	116	11	mice	mouse	NNS
cord-355413-ls2nud43	116	12	to	to	IN
cord-355413-ls2nud43	116	13	TMEV	TMEV	NNP
cord-355413-ls2nud43	116	14	.	.	.
cord-355413-ls2nud43	117	1	When	when	WRB
cord-355413-ls2nud43	117	2	resistant	resistant	JJ
cord-355413-ls2nud43	117	3	(	(	-LRB-
cord-355413-ls2nud43	117	4	C57BL/10	c57bl/10	ADD
cord-355413-ls2nud43	117	5	)	)	-RRB-
cord-355413-ls2nud43	118	1	mice	mouse	NNS
cord-355413-ls2nud43	118	2	were	be	VBD
cord-355413-ls2nud43	118	3	depleted	deplete	VBN
cord-355413-ls2nud43	118	4	of	of	IN
cord-355413-ls2nud43	118	5	NK	NK	NNP
cord-355413-ls2nud43	118	6	cells	cell	NNS
cord-355413-ls2nud43	118	7	using	use	VBG
cord-355413-ls2nud43	118	8	either	either	CC
cord-355413-ls2nud43	118	9	mAb	mAb	NNPS
cord-355413-ls2nud43	118	10	NK1.1	nk1.1	NN
cord-355413-ls2nud43	118	11	or	or	CC
cord-355413-ls2nud43	118	12	polyclonal	polyclonal	JJ
cord-355413-ls2nud43	118	13	anti	anti	JJ
cord-355413-ls2nud43	118	14	-	-	JJ
cord-355413-ls2nud43	118	15	asialo	asialo	JJ
cord-355413-ls2nud43	118	16	-	-	HYPH
cord-355413-ls2nud43	118	17	GM1	GM1	NNP
cord-355413-ls2nud43	119	1	,	,	,
cord-355413-ls2nud43	119	2	TMEV	TMEV	NNP
cord-355413-ls2nud43	119	3	induced	induce	VBD
cord-355413-ls2nud43	119	4	the	the	DT
cord-355413-ls2nud43	119	5	development	development	NN
cord-355413-ls2nud43	119	6	of	of	IN
cord-355413-ls2nud43	119	7	diffuse	diffuse	NN
cord-355413-ls2nud43	119	8	encephalitis	encephalitis	NN
cord-355413-ls2nud43	119	9	and	and	CC
cord-355413-ls2nud43	119	10	meningitis	meningitis	NN
cord-355413-ls2nud43	119	11	early	early	RB
cord-355413-ls2nud43	119	12	in	in	IN
cord-355413-ls2nud43	119	13	the	the	DT
cord-355413-ls2nud43	119	14	post	post	JJ
cord-355413-ls2nud43	119	15	-	-	JJ
cord-355413-ls2nud43	119	16	infection	infection	JJ
cord-355413-ls2nud43	119	17	period	period	NN
cord-355413-ls2nud43	119	18	.	.	.
cord-355413-ls2nud43	120	1	However	however	RB
cord-355413-ls2nud43	120	2	,	,	,
cord-355413-ls2nud43	120	3	the	the	DT
cord-355413-ls2nud43	120	4	second	second	JJ
cord-355413-ls2nud43	120	5	phase	phase	NN
cord-355413-ls2nud43	120	6	of	of	IN
cord-355413-ls2nud43	120	7	TMEV	TMEV	NNP
cord-355413-ls2nud43	120	8	-	-	HYPH
cord-355413-ls2nud43	120	9	induced	induce	VBN
cord-355413-ls2nud43	120	10	CNS	CNS	NNP
cord-355413-ls2nud43	120	11	disease	disease	NN
cord-355413-ls2nud43	120	12	(	(	-LRB-
cord-355413-ls2nud43	120	13	demyelination	demyelination	NN
cord-355413-ls2nud43	120	14	)	)	-RRB-
cord-355413-ls2nud43	120	15	was	be	VBD
cord-355413-ls2nud43	120	16	observed	observe	VBN
cord-355413-ls2nud43	120	17	only	only	RB
cord-355413-ls2nud43	120	18	in	in	IN
cord-355413-ls2nud43	120	19	resistant	resistant	JJ
cord-355413-ls2nud43	120	20	C57BL/10	C57BL/10	NNP
cord-355413-ls2nud43	120	21	mice	mouse	NNS
cord-355413-ls2nud43	120	22	treated	treat	VBN
cord-355413-ls2nud43	120	23	with	with	IN
cord-355413-ls2nud43	120	24	anti	anti	JJ
cord-355413-ls2nud43	120	25	-	-	JJ
cord-355413-ls2nud43	120	26	asialo	asialo	JJ
cord-355413-ls2nud43	120	27	-	-	HYPH
cord-355413-ls2nud43	120	28	GM1	GM1	NNP
cord-355413-ls2nud43	120	29	.	.	.
cord-355413-ls2nud43	121	1	Experiments	experiment	NNS
cord-355413-ls2nud43	121	2	with	with	IN
cord-355413-ls2nud43	121	3	beige	beige	JJ
cord-355413-ls2nud43	121	4	/	/	SYM
cord-355413-ls2nud43	121	5	beige	beige	JJ
cord-355413-ls2nud43	121	6	mice	mouse	NNS
cord-355413-ls2nud43	121	7	of	of	IN
cord-355413-ls2nud43	121	8	C57BL/10	c57bl/10	JJ
cord-355413-ls2nud43	121	9	background	background	NN
cord-355413-ls2nud43	121	10	showed	show	VBD
cord-355413-ls2nud43	121	11	a	a	DT
cord-355413-ls2nud43	121	12	mild	mild	JJ
cord-355413-ls2nud43	121	13	degree	degree	NN
cord-355413-ls2nud43	121	14	of	of	IN
cord-355413-ls2nud43	121	15	grey	grey	JJ
cord-355413-ls2nud43	121	16	matter	matter	NN
cord-355413-ls2nud43	121	17	inflammation	inflammation	NN
cord-355413-ls2nud43	121	18	but	but	CC
cord-355413-ls2nud43	121	19	no	no	DT
cord-355413-ls2nud43	121	20	demyelination	demyelination	NN
cord-355413-ls2nud43	121	21	(	(	-LRB-
cord-355413-ls2nud43	121	22	Paya	Paya	NNP
cord-355413-ls2nud43	121	23	et	et	NNP
cord-355413-ls2nud43	121	24	al	al	NNP
cord-355413-ls2nud43	121	25	.	.	NNP
cord-355413-ls2nud43	121	26	,	,	,
cord-355413-ls2nud43	121	27	1989	1989	CD
cord-355413-ls2nud43	121	28	)	)	-RRB-
cord-355413-ls2nud43	121	29	.	.	.
cord-355413-ls2nud43	122	1	NK	NK	NNP
cord-355413-ls2nud43	122	2	cells	cell	NNS
cord-355413-ls2nud43	122	3	are	be	VBP
cord-355413-ls2nud43	122	4	critical	critical	JJ
cord-355413-ls2nud43	122	5	effectors	effector	NNS
cord-355413-ls2nud43	122	6	in	in	IN
cord-355413-ls2nud43	122	7	protecting	protect	VBG
cord-355413-ls2nud43	122	8	against	against	IN
cord-355413-ls2nud43	122	9	TMEV	TMEV	NNP
cord-355413-ls2nud43	122	10	-	-	HYPH
cord-355413-ls2nud43	122	11	induced	induce	VBN
cord-355413-ls2nud43	122	12	grey	grey	JJ
cord-355413-ls2nud43	122	13	matter	matter	NN
cord-355413-ls2nud43	122	14	disease	disease	NN
cord-355413-ls2nud43	122	15	,	,	,
cord-355413-ls2nud43	122	16	whereas	whereas	IN
cord-355413-ls2nud43	122	17	a	a	DT
cord-355413-ls2nud43	122	18	different	different	JJ
cord-355413-ls2nud43	122	19	population	population	NN
cord-355413-ls2nud43	122	20	of	of	IN
cord-355413-ls2nud43	122	21	either	either	DT
cord-355413-ls2nud43	122	22	NK1.1-NK	NK1.1-NK	NNP
cord-355413-ls2nud43	122	23	cells	cell	NNS
cord-355413-ls2nud43	122	24	,	,	,
cord-355413-ls2nud43	122	25	or	or	CC
cord-355413-ls2nud43	122	26	other	other	JJ
cord-355413-ls2nud43	122	27	activated	activate	VBN
cord-355413-ls2nud43	122	28	lymphocytes	lymphocyte	NNS
cord-355413-ls2nud43	122	29	,	,	,
cord-355413-ls2nud43	122	30	may	may	MD
cord-355413-ls2nud43	122	31	be	be	VB
cord-355413-ls2nud43	122	32	critical	critical	JJ
cord-355413-ls2nud43	122	33	in	in	IN
cord-355413-ls2nud43	122	34	resistance	resistance	NN
cord-355413-ls2nud43	122	35	or	or	CC
cord-355413-ls2nud43	122	36	susceptibility	susceptibility	NN
cord-355413-ls2nud43	122	37	to	to	IN
cord-355413-ls2nud43	122	38	demyelination	demyelination	NN
cord-355413-ls2nud43	122	39	.	.	.
cord-355413-ls2nud43	123	1	In	in	IN
cord-355413-ls2nud43	123	2	support	support	NN
cord-355413-ls2nud43	123	3	of	of	IN
cord-355413-ls2nud43	123	4	the	the	DT
cord-355413-ls2nud43	123	5	involvement	involvement	NN
cord-355413-ls2nud43	123	6	of	of	IN
cord-355413-ls2nud43	123	7	NK	NK	NNP
cord-355413-ls2nud43	123	8	cells	cell	NNS
cord-355413-ls2nud43	123	9	during	during	IN
cord-355413-ls2nud43	123	10	TMEV	TMEV	NNP
cord-355413-ls2nud43	123	11	of	of	IN
cord-355413-ls2nud43	123	12	the	the	DT
cord-355413-ls2nud43	123	13	CNS	CNS	NNP
cord-355413-ls2nud43	123	14	,	,	,
cord-355413-ls2nud43	123	15	another	another	DT
cord-355413-ls2nud43	123	16	study	study	NN
cord-355413-ls2nud43	123	17	demonstrated	demonstrate	VBD
cord-355413-ls2nud43	123	18	that	that	IN
cord-355413-ls2nud43	123	19	stressed	stress	VBD
cord-355413-ls2nud43	123	20	mice	mouse	NNS
cord-355413-ls2nud43	123	21	developed	develop	VBD
cord-355413-ls2nud43	123	22	clinical	clinical	JJ
cord-355413-ls2nud43	123	23	signs	sign	NNS
cord-355413-ls2nud43	123	24	of	of	IN
cord-355413-ls2nud43	123	25	encephalitis	encephalitis	RB
cord-355413-ls2nud43	123	26	,	,	,
cord-355413-ls2nud43	123	27	thymic	thymic	JJ
cord-355413-ls2nud43	123	28	atrophy	atrophy	NN
cord-355413-ls2nud43	123	29	,	,	,
cord-355413-ls2nud43	123	30	and	and	CC
cord-355413-ls2nud43	123	31	adrenal	adrenal	JJ
cord-355413-ls2nud43	123	32	hypertrophy	hypertrophy	NN
cord-355413-ls2nud43	123	33	after	after	IN
cord-355413-ls2nud43	123	34	infection	infection	NN
cord-355413-ls2nud43	123	35	with	with	IN
cord-355413-ls2nud43	123	36	Theiler	Theiler	NNP
cord-355413-ls2nud43	123	37	's	's	POS
cord-355413-ls2nud43	123	38	virus	virus	NN
cord-355413-ls2nud43	123	39	(	(	-LRB-
cord-355413-ls2nud43	123	40	Welsh	Welsh	NNP
cord-355413-ls2nud43	123	41	et	et	NNP
cord-355413-ls2nud43	123	42	al	al	NNP
cord-355413-ls2nud43	123	43	.	.	NNP
cord-355413-ls2nud43	123	44	,	,	,
cord-355413-ls2nud43	123	45	2004	2004	CD
cord-355413-ls2nud43	123	46	)	)	-RRB-
cord-355413-ls2nud43	123	47	.	.	.
cord-355413-ls2nud43	124	1	This	this	DT
cord-355413-ls2nud43	124	2	syndrome	syndrome	NN
cord-355413-ls2nud43	124	3	was	be	VBD
cord-355413-ls2nud43	124	4	associated	associate	VBN
cord-355413-ls2nud43	124	5	with	with	IN
cord-355413-ls2nud43	124	6	significantly	significantly	RB
cord-355413-ls2nud43	124	7	reduced	reduce	VBN
cord-355413-ls2nud43	124	8	virus	virus	NN
cord-355413-ls2nud43	124	9	-	-	HYPH
cord-355413-ls2nud43	124	10	induced	induce	VBN
cord-355413-ls2nud43	124	11	NK	NK	NNP
cord-355413-ls2nud43	124	12	cell	cell	NN
cord-355413-ls2nud43	124	13	cytotoxic	cytotoxic	JJ
cord-355413-ls2nud43	124	14	activity	activity	NN
cord-355413-ls2nud43	124	15	in	in	IN
cord-355413-ls2nud43	124	16	restrained	restrained	JJ
cord-355413-ls2nud43	124	17	mice	mouse	NNS
cord-355413-ls2nud43	124	18	at	at	IN
cord-355413-ls2nud43	124	19	1	1	CD
cord-355413-ls2nud43	124	20	day	day	NN
cord-355413-ls2nud43	124	21	post	post	NN
cord-355413-ls2nud43	124	22	-	-	NN
cord-355413-ls2nud43	124	23	infection	infection	NN
cord-355413-ls2nud43	124	24	,	,	,
cord-355413-ls2nud43	124	25	which	which	WDT
cord-355413-ls2nud43	124	26	may	may	MD
cord-355413-ls2nud43	124	27	account	account	VB
cord-355413-ls2nud43	124	28	for	for	IN
cord-355413-ls2nud43	124	29	the	the	DT
cord-355413-ls2nud43	124	30	reduced	reduce	VBN
cord-355413-ls2nud43	124	31	viral	viral	JJ
cord-355413-ls2nud43	124	32	clearance	clearance	NN
cord-355413-ls2nud43	124	33	from	from	IN
cord-355413-ls2nud43	124	34	the	the	DT
cord-355413-ls2nud43	124	35	CNS	CNS	NNP
cord-355413-ls2nud43	124	36	.	.	.
cord-355413-ls2nud43	125	1	Mouse	Mouse	NNP
cord-355413-ls2nud43	125	2	hepatitis	hepatitis	NN
cord-355413-ls2nud43	125	3	virus	virus	NN
cord-355413-ls2nud43	125	4	(	(	-LRB-
cord-355413-ls2nud43	125	5	MHV	MHV	NNP
cord-355413-ls2nud43	125	6	)	)	-RRB-
cord-355413-ls2nud43	125	7	is	be	VBZ
cord-355413-ls2nud43	125	8	a	a	DT
cord-355413-ls2nud43	125	9	coronavirus	coronavirus	NN
cord-355413-ls2nud43	125	10	that	that	WDT
cord-355413-ls2nud43	125	11	causes	cause	VBZ
cord-355413-ls2nud43	125	12	infection	infection	NN
cord-355413-ls2nud43	125	13	of	of	IN
cord-355413-ls2nud43	125	14	the	the	DT
cord-355413-ls2nud43	125	15	CNS	CNS	NNP
cord-355413-ls2nud43	125	16	(	(	-LRB-
cord-355413-ls2nud43	125	17	Marten	Marten	NNP
cord-355413-ls2nud43	125	18	et	et	NNP
cord-355413-ls2nud43	125	19	al	al	NNP
cord-355413-ls2nud43	125	20	.	.	NNP
cord-355413-ls2nud43	125	21	,	,	,
cord-355413-ls2nud43	125	22	2001	2001	CD
cord-355413-ls2nud43	125	23	;	;	:
cord-355413-ls2nud43	125	24	Wang	Wang	NNP
cord-355413-ls2nud43	125	25	et	et	NNP
cord-355413-ls2nud43	125	26	al	al	NNP
cord-355413-ls2nud43	125	27	.	.	NNP
cord-355413-ls2nud43	125	28	,	,	,
cord-355413-ls2nud43	125	29	1990	1990	CD
cord-355413-ls2nud43	125	30	)	)	-RRB-
cord-355413-ls2nud43	125	31	.	.	.
cord-355413-ls2nud43	126	1	Intracerebral	intracerebral	JJ
cord-355413-ls2nud43	126	2	infection	infection	NN
cord-355413-ls2nud43	126	3	of	of	IN
cord-355413-ls2nud43	126	4	susceptible	susceptible	JJ
cord-355413-ls2nud43	126	5	strains	strain	NNS
cord-355413-ls2nud43	126	6	of	of	IN
cord-355413-ls2nud43	126	7	mice	mouse	NNS
cord-355413-ls2nud43	126	8	with	with	IN
cord-355413-ls2nud43	126	9	MHV	MHV	NNP
cord-355413-ls2nud43	126	10	results	result	NNS
cord-355413-ls2nud43	126	11	in	in	IN
cord-355413-ls2nud43	126	12	an	an	DT
cord-355413-ls2nud43	126	13	acute	acute	JJ
cord-355413-ls2nud43	126	14	encephalomyelitis	encephalomyelitis	NN
cord-355413-ls2nud43	126	15	followed	follow	VBN
cord-355413-ls2nud43	126	16	by	by	IN
cord-355413-ls2nud43	126	17	a	a	DT
cord-355413-ls2nud43	126	18	chronic	chronic	JJ
cord-355413-ls2nud43	126	19	immune	immune	NN
cord-355413-ls2nud43	126	20	-	-	HYPH
cord-355413-ls2nud43	126	21	mediated	mediate	VBN
cord-355413-ls2nud43	126	22	demyelinating	demyelinating	NN
cord-355413-ls2nud43	126	23	disease	disease	NN
cord-355413-ls2nud43	126	24	that	that	WDT
cord-355413-ls2nud43	126	25	is	be	VBZ
cord-355413-ls2nud43	126	26	similar	similar	JJ
cord-355413-ls2nud43	126	27	in	in	IN
cord-355413-ls2nud43	126	28	pathology	pathology	NN
cord-355413-ls2nud43	126	29	to	to	IN
cord-355413-ls2nud43	126	30	the	the	DT
cord-355413-ls2nud43	126	31	human	human	JJ
cord-355413-ls2nud43	126	32	demyelinating	demyelinate	VBG
cord-355413-ls2nud43	126	33	disease	disease	NN
cord-355413-ls2nud43	126	34	MS	MS	NNP
cord-355413-ls2nud43	126	35	(	(	-LRB-
cord-355413-ls2nud43	126	36	Walsh	Walsh	NNP
cord-355413-ls2nud43	126	37	et	et	NNP
cord-355413-ls2nud43	126	38	al	al	NNP
cord-355413-ls2nud43	126	39	.	.	NNP
cord-355413-ls2nud43	126	40	,	,	,
cord-355413-ls2nud43	126	41	2007	2007	CD
cord-355413-ls2nud43	126	42	;	;	:
cord-355413-ls2nud43	126	43	Zuo	Zuo	NNP
cord-355413-ls2nud43	126	44	et	et	FW
cord-355413-ls2nud43	126	45	al	al	NNP
cord-355413-ls2nud43	126	46	.	.	NNP
cord-355413-ls2nud43	126	47	,	,	,
cord-355413-ls2nud43	126	48	2006	2006	CD
cord-355413-ls2nud43	126	49	)	)	-RRB-
cord-355413-ls2nud43	126	50	.	.	.
cord-355413-ls2nud43	127	1	Intracerebral	intracerebral	JJ
cord-355413-ls2nud43	127	2	infection	infection	NN
cord-355413-ls2nud43	127	3	of	of	IN
cord-355413-ls2nud43	127	4	RAG1	RAG1	NNP
cord-355413-ls2nud43	127	5	/	/	NNS
cord-355413-ls2nud43	127	6	mice	mouse	NNS
cord-355413-ls2nud43	127	7	with	with	IN
cord-355413-ls2nud43	127	8	a	a	DT
cord-355413-ls2nud43	127	9	recombinant	recombinant	JJ
cord-355413-ls2nud43	127	10	CXCL10-expressing	cxcl10-expresse	VBG
cord-355413-ls2nud43	127	11	murine	murine	JJ
cord-355413-ls2nud43	127	12	coronavirus	coronavirus	NN
cord-355413-ls2nud43	127	13	(	(	-LRB-
cord-355413-ls2nud43	127	14	MHV	MHV	NNP
cord-355413-ls2nud43	127	15	)	)	-RRB-
cord-355413-ls2nud43	127	16	resulted	result	VBD
cord-355413-ls2nud43	127	17	in	in	IN
cord-355413-ls2nud43	127	18	protection	protection	NN
cord-355413-ls2nud43	127	19	from	from	IN
cord-355413-ls2nud43	127	20	disease	disease	NN
cord-355413-ls2nud43	127	21	and	and	CC
cord-355413-ls2nud43	127	22	increased	increase	VBN
cord-355413-ls2nud43	127	23	survival	survival	NN
cord-355413-ls2nud43	127	24	that	that	WDT
cord-355413-ls2nud43	127	25	correlated	correlate	VBD
cord-355413-ls2nud43	127	26	with	with	IN
cord-355413-ls2nud43	127	27	a	a	DT
cord-355413-ls2nud43	127	28	significant	significant	JJ
cord-355413-ls2nud43	127	29	increase	increase	NN
cord-355413-ls2nud43	127	30	in	in	IN
cord-355413-ls2nud43	127	31	recruitment	recruitment	NN
cord-355413-ls2nud43	127	32	and	and	CC
cord-355413-ls2nud43	127	33	activation	activation	NN
cord-355413-ls2nud43	127	34	of	of	IN
cord-355413-ls2nud43	127	35	NK	NK	NNP
cord-355413-ls2nud43	127	36	cells	cell	NNS
cord-355413-ls2nud43	127	37	within	within	IN
cord-355413-ls2nud43	127	38	the	the	DT
cord-355413-ls2nud43	127	39	CNS	CNS	NNP
cord-355413-ls2nud43	127	40	(	(	-LRB-
cord-355413-ls2nud43	127	41	Walsh	Walsh	NNP
cord-355413-ls2nud43	127	42	et	et	NNP
cord-355413-ls2nud43	127	43	al	al	NNP
cord-355413-ls2nud43	127	44	.	.	NNP
cord-355413-ls2nud43	127	45	,	,	,
cord-355413-ls2nud43	127	46	2007	2007	CD
cord-355413-ls2nud43	127	47	)	)	-RRB-
cord-355413-ls2nud43	127	48	.	.	.
cord-355413-ls2nud43	128	1	Accumulation	accumulation	NN
cord-355413-ls2nud43	128	2	of	of	IN
cord-355413-ls2nud43	128	3	NK	NK	NNP
cord-355413-ls2nud43	128	4	cells	cell	NNS
cord-355413-ls2nud43	128	5	resulted	result	VBD
cord-355413-ls2nud43	128	6	in	in	IN
cord-355413-ls2nud43	128	7	a	a	DT
cord-355413-ls2nud43	128	8	reduction	reduction	NN
cord-355413-ls2nud43	128	9	in	in	IN
cord-355413-ls2nud43	128	10	viral	viral	JJ
cord-355413-ls2nud43	128	11	titres	titre	NNS
cord-355413-ls2nud43	128	12	that	that	WDT
cord-355413-ls2nud43	128	13	was	be	VBD
cord-355413-ls2nud43	128	14	dependant	dependant	JJ
cord-355413-ls2nud43	128	15	on	on	IN
cord-355413-ls2nud43	128	16	IFN-	ifn-	DT
cord-355413-ls2nud43	128	17	secretion	secretion	NN
cord-355413-ls2nud43	128	18	(	(	-LRB-
cord-355413-ls2nud43	128	19	Walsh	Walsh	NNP
cord-355413-ls2nud43	128	20	et	et	NNP
cord-355413-ls2nud43	128	21	al	al	NNP
cord-355413-ls2nud43	128	22	.	.	NNP
cord-355413-ls2nud43	128	23	,	,	,
cord-355413-ls2nud43	128	24	2007	2007	CD
cord-355413-ls2nud43	128	25	)	)	-RRB-
cord-355413-ls2nud43	128	26	.	.	.
cord-355413-ls2nud43	129	1	These	these	DT
cord-355413-ls2nud43	129	2	results	result	NNS
cord-355413-ls2nud43	129	3	indicate	indicate	VBP
cord-355413-ls2nud43	129	4	that	that	IN
cord-355413-ls2nud43	129	5	the	the	DT
cord-355413-ls2nud43	129	6	CXCL10-guided	cxcl10-guided	JJ
cord-355413-ls2nud43	129	7	NK	NK	NNP
cord-355413-ls2nud43	129	8	cell	cell	NN
cord-355413-ls2nud43	129	9	homing	homing	NN
cord-355413-ls2nud43	129	10	to	to	IN
cord-355413-ls2nud43	129	11	the	the	DT
cord-355413-ls2nud43	129	12	CNS	CNS	NNP
cord-355413-ls2nud43	129	13	might	may	MD
cord-355413-ls2nud43	129	14	play	play	VB
cord-355413-ls2nud43	129	15	a	a	DT
cord-355413-ls2nud43	129	16	pivotal	pivotal	JJ
cord-355413-ls2nud43	129	17	role	role	NN
cord-355413-ls2nud43	129	18	in	in	IN
cord-355413-ls2nud43	129	19	defence	defence	NN
cord-355413-ls2nud43	129	20	following	follow	VBG
cord-355413-ls2nud43	129	21	coronavirus	coronavirus	NN
cord-355413-ls2nud43	129	22	infection	infection	NN
cord-355413-ls2nud43	129	23	of	of	IN
cord-355413-ls2nud43	129	24	the	the	DT
cord-355413-ls2nud43	129	25	CNS	CNS	NNP
cord-355413-ls2nud43	129	26	.	.	.
cord-355413-ls2nud43	130	1	Semliki	Semliki	NNP
cord-355413-ls2nud43	130	2	Forest	Forest	NNP
cord-355413-ls2nud43	130	3	virus	virus	NN
cord-355413-ls2nud43	130	4	(	(	-LRB-
cord-355413-ls2nud43	130	5	SFV	SFV	NNP
cord-355413-ls2nud43	130	6	)	)	-RRB-
cord-355413-ls2nud43	130	7	is	be	VBZ
cord-355413-ls2nud43	130	8	a	a	DT
cord-355413-ls2nud43	130	9	positive	positive	JJ
cord-355413-ls2nud43	130	10	-	-	HYPH
cord-355413-ls2nud43	130	11	stranded	strand	VBN
cord-355413-ls2nud43	130	12	RNA	RNA	NNP
cord-355413-ls2nud43	130	13	virus	virus	NN
cord-355413-ls2nud43	130	14	(	(	-LRB-
cord-355413-ls2nud43	130	15	Atkins	Atkins	NNP
cord-355413-ls2nud43	130	16	et	et	NNP
cord-355413-ls2nud43	130	17	al	al	NNP
cord-355413-ls2nud43	130	18	.	.	NNP
cord-355413-ls2nud43	130	19	,	,	,
cord-355413-ls2nud43	130	20	1999	1999	CD
cord-355413-ls2nud43	130	21	;	;	:
cord-355413-ls2nud43	130	22	Smithburn	Smithburn	NNP
cord-355413-ls2nud43	130	23	and	and	CC
cord-355413-ls2nud43	130	24	Haddow	Haddow	NNP
cord-355413-ls2nud43	130	25	,	,	,
cord-355413-ls2nud43	130	26	1944	1944	CD
cord-355413-ls2nud43	130	27	)	)	-RRB-
cord-355413-ls2nud43	130	28	.	.	.
cord-355413-ls2nud43	131	1	Infection	infection	NN
cord-355413-ls2nud43	131	2	of	of	IN
cord-355413-ls2nud43	131	3	C57BL/6	C57BL/6	NNP
cord-355413-ls2nud43	131	4	mice	mouse	NNS
cord-355413-ls2nud43	131	5	with	with	IN
cord-355413-ls2nud43	131	6	SFV	SFV	NNP
cord-355413-ls2nud43	131	7	leads	lead	VBZ
cord-355413-ls2nud43	131	8	to	to	TO
cord-355413-ls2nud43	131	9	pronounced	pronounced	VB
cord-355413-ls2nud43	131	10	CNS	cns	JJ
cord-355413-ls2nud43	131	11	cellular	cellular	JJ
cord-355413-ls2nud43	131	12	infiltration	infiltration	NN
cord-355413-ls2nud43	131	13	and	and	CC
cord-355413-ls2nud43	131	14	apoptosis	apoptosis	NN
cord-355413-ls2nud43	131	15	of	of	IN
cord-355413-ls2nud43	131	16	microglial	microglial	JJ
cord-355413-ls2nud43	131	17	and	and	CC
cord-355413-ls2nud43	131	18	neuronal	neuronal	JJ
cord-355413-ls2nud43	131	19	cells	cell	NNS
cord-355413-ls2nud43	132	1	(	(	-LRB-
cord-355413-ls2nud43	132	2	Alsharifi	Alsharifi	NNP
cord-355413-ls2nud43	132	3	et	et	NNP
cord-355413-ls2nud43	132	4	al	al	NNP
cord-355413-ls2nud43	132	5	.	.	NNP
cord-355413-ls2nud43	132	6	,	,	,
cord-355413-ls2nud43	132	7	2006	2006	CD
cord-355413-ls2nud43	132	8	)	)	-RRB-
cord-355413-ls2nud43	132	9	.	.	.
cord-355413-ls2nud43	133	1	In	in	IN
cord-355413-ls2nud43	133	2	this	this	DT
cord-355413-ls2nud43	133	3	model	model	NN
cord-355413-ls2nud43	133	4	,	,	,
cord-355413-ls2nud43	133	5	NK	NK	NNP
cord-355413-ls2nud43	133	6	cells	cell	NNS
cord-355413-ls2nud43	133	7	and	and	CC
cord-355413-ls2nud43	133	8	,	,	,
cord-355413-ls2nud43	133	9	to	to	IN
cord-355413-ls2nud43	133	10	a	a	DT
cord-355413-ls2nud43	133	11	lesser	less	JJR
cord-355413-ls2nud43	133	12	degree	degree	NN
cord-355413-ls2nud43	133	13	,	,	,
cord-355413-ls2nud43	133	14	cytotoxic	cytotoxic	JJ
cord-355413-ls2nud43	133	15	T	t	NN
cord-355413-ls2nud43	133	16	cells	cell	NNS
cord-355413-ls2nud43	133	17	are	be	VBP
cord-355413-ls2nud43	133	18	major	major	JJ
cord-355413-ls2nud43	133	19	contributors	contributor	NNS
cord-355413-ls2nud43	133	20	in	in	IN
cord-355413-ls2nud43	133	21	combating	combat	VBG
cord-355413-ls2nud43	133	22	SFV	sfv	NN
cord-355413-ls2nud43	133	23	infection	infection	NN
cord-355413-ls2nud43	133	24	.	.	.
cord-355413-ls2nud43	134	1	Mice	mouse	NNS
cord-355413-ls2nud43	134	2	lacking	lack	VBG
cord-355413-ls2nud43	134	3	the	the	DT
cord-355413-ls2nud43	134	4	Tc	Tc	NNP
cord-355413-ls2nud43	134	5	cell	cell	NN
cord-355413-ls2nud43	134	6	compartment	compartment	NN
cord-355413-ls2nud43	134	7	(	(	-LRB-
cord-355413-ls2nud43	134	8			CD
cord-355413-ls2nud43	134	9	2	2	CD
cord-355413-ls2nud43	134	10	-microglobulin	-microglobulin	JJ
cord-355413-ls2nud43	134	11	-	-	HYPH
cord-355413-ls2nud43	134	12	deficient	deficient	JJ
cord-355413-ls2nud43	134	13	mice	mouse	NNS
cord-355413-ls2nud43	134	14	,	,	,
cord-355413-ls2nud43	134	15	and	and	CC
cord-355413-ls2nud43	134	16	thus	thus	RB
cord-355413-ls2nud43	134	17	CD8	CD8	NNP
cord-355413-ls2nud43	134	18			NNP
cord-355413-ls2nud43	134	19	T	T	NNP
cord-355413-ls2nud43	134	20	cells	cell	NNS
cord-355413-ls2nud43	134	21	)	)	-RRB-
cord-355413-ls2nud43	134	22	exhibit	exhibit	NN
cord-355413-ls2nud43	134	23	susceptibility	susceptibility	NN
cord-355413-ls2nud43	134	24	similar	similar	JJ
cord-355413-ls2nud43	134	25	to	to	IN
cord-355413-ls2nud43	134	26	wild	wild	JJ
cord-355413-ls2nud43	134	27	-	-	HYPH
cord-355413-ls2nud43	134	28	type	type	NN
cord-355413-ls2nud43	134	29	mice	mouse	NNS
cord-355413-ls2nud43	134	30	.	.	.
cord-355413-ls2nud43	135	1	Depletion	depletion	NN
cord-355413-ls2nud43	135	2	of	of	IN
cord-355413-ls2nud43	135	3	NK	NK	NNP
cord-355413-ls2nud43	135	4	cells	cell	NNS
cord-355413-ls2nud43	135	5	significantly	significantly	RB
cord-355413-ls2nud43	135	6	delayed	delay	VBD
cord-355413-ls2nud43	135	7	the	the	DT
cord-355413-ls2nud43	135	8	mean	mean	JJ
cord-355413-ls2nud43	135	9	time	time	NN
cord-355413-ls2nud43	135	10	to	to	IN
cord-355413-ls2nud43	135	11	death	death	NN
cord-355413-ls2nud43	135	12	but	but	CC
cord-355413-ls2nud43	135	13	did	do	VBD
cord-355413-ls2nud43	135	14	not	not	RB
cord-355413-ls2nud43	135	15	prevent	prevent	VB
cord-355413-ls2nud43	135	16	mortality	mortality	NN
cord-355413-ls2nud43	135	17	in	in	IN
cord-355413-ls2nud43	135	18	SFV	sfv	NN
cord-355413-ls2nud43	135	19	-	-	HYPH
cord-355413-ls2nud43	135	20	infected	infect	VBN
cord-355413-ls2nud43	135	21	B6	b6	NN
cord-355413-ls2nud43	135	22	mice	mouse	NNS
cord-355413-ls2nud43	135	23	suggesting	suggest	VBG
cord-355413-ls2nud43	135	24	that	that	IN
cord-355413-ls2nud43	135	25	cytolytic	cytolytic	JJ
cord-355413-ls2nud43	135	26	activity	activity	NN
cord-355413-ls2nud43	135	27	of	of	IN
cord-355413-ls2nud43	135	28	NK	NK	NNP
cord-355413-ls2nud43	135	29	cells	cell	NNS
cord-355413-ls2nud43	135	30	is	be	VBZ
cord-355413-ls2nud43	135	31	detrimental	detrimental	JJ
cord-355413-ls2nud43	135	32	,	,	,
cord-355413-ls2nud43	135	33	while	while	IN
cord-355413-ls2nud43	135	34	IFN-	ifn-	DT
cord-355413-ls2nud43	135	35	production	production	NN
cord-355413-ls2nud43	135	36	is	be	VBZ
cord-355413-ls2nud43	135	37	beneficial	beneficial	JJ
cord-355413-ls2nud43	135	38	for	for	IN
cord-355413-ls2nud43	135	39	recovery	recovery	NN
cord-355413-ls2nud43	135	40	from	from	IN
cord-355413-ls2nud43	135	41	SFV	sfv	NN
cord-355413-ls2nud43	135	42	infection	infection	NN
cord-355413-ls2nud43	136	1	(	(	-LRB-
cord-355413-ls2nud43	136	2	Alsharifi	Alsharifi	NNP
cord-355413-ls2nud43	136	3	et	et	NNP
cord-355413-ls2nud43	136	4	al	al	NNP
cord-355413-ls2nud43	136	5	.	.	NNP
cord-355413-ls2nud43	136	6	,	,	,
cord-355413-ls2nud43	136	7	2006	2006	CD
cord-355413-ls2nud43	136	8	)	)	-RRB-
cord-355413-ls2nud43	136	9	.	.	.
cord-355413-ls2nud43	137	1	With	with	IN
cord-355413-ls2nud43	137	2	greater	great	JJR
cord-355413-ls2nud43	137	3	than	than	IN
cord-355413-ls2nud43	137	4	1.6	1.6	CD
cord-355413-ls2nud43	137	5	million	million	CD
cord-355413-ls2nud43	137	6	Americans	Americans	NNPS
cord-355413-ls2nud43	137	7	infected	infect	VBN
cord-355413-ls2nud43	137	8	annually	annually	RB
cord-355413-ls2nud43	138	1	(	(	-LRB-
cord-355413-ls2nud43	138	2	Armstrong	Armstrong	NNP
cord-355413-ls2nud43	138	3	et	et	NNP
cord-355413-ls2nud43	138	4	al	al	NNP
cord-355413-ls2nud43	138	5	.	.	NNP
cord-355413-ls2nud43	138	6	,	,	,
cord-355413-ls2nud43	138	7	2001	2001	CD
cord-355413-ls2nud43	138	8	)	)	-RRB-
cord-355413-ls2nud43	138	9	,	,	,
cord-355413-ls2nud43	138	10	herpes	herpes	NNP
cord-355413-ls2nud43	138	11	simplex	simplex	NNP
cord-355413-ls2nud43	138	12	virus	virus	NN
cord-355413-ls2nud43	138	13	type	type	NN
cord-355413-ls2nud43	138	14	1	1	CD
cord-355413-ls2nud43	138	15	and	and	CC
cord-355413-ls2nud43	138	16	2	2	CD
cord-355413-ls2nud43	138	17	(	(	-LRB-
cord-355413-ls2nud43	138	18	HSV-1	hsv-1	NN
cord-355413-ls2nud43	138	19	,	,	,
cord-355413-ls2nud43	138	20	HSV-2	HSV-2	NNP
cord-355413-ls2nud43	138	21	)	)	-RRB-
cord-355413-ls2nud43	138	22	are	be	VBP
cord-355413-ls2nud43	138	23	pathogens	pathogen	NNS
cord-355413-ls2nud43	138	24	with	with	IN
cord-355413-ls2nud43	138	25	a	a	DT
cord-355413-ls2nud43	138	26	significant	significant	JJ
cord-355413-ls2nud43	138	27	impact	impact	NN
cord-355413-ls2nud43	138	28	on	on	IN
cord-355413-ls2nud43	138	29	public	public	JJ
cord-355413-ls2nud43	138	30	health	health	NN
cord-355413-ls2nud43	138	31	.	.	.
cord-355413-ls2nud43	139	1	Typically	typically	RB
cord-355413-ls2nud43	139	2	,	,	,
cord-355413-ls2nud43	139	3	infection	infection	NN
cord-355413-ls2nud43	139	4	results	result	VBZ
cord-355413-ls2nud43	139	5	in	in	IN
cord-355413-ls2nud43	139	6	a	a	DT
cord-355413-ls2nud43	139	7	life	life	NN
cord-355413-ls2nud43	139	8	-	-	HYPH
cord-355413-ls2nud43	139	9	long	long	JJ
cord-355413-ls2nud43	139	10	latent	latent	JJ
cord-355413-ls2nud43	139	11	infection	infection	NN
cord-355413-ls2nud43	139	12	of	of	IN
cord-355413-ls2nud43	139	13	the	the	DT
cord-355413-ls2nud43	139	14	host	host	NN
cord-355413-ls2nud43	139	15	(	(	-LRB-
cord-355413-ls2nud43	139	16	Halioua	Halioua	NNP
cord-355413-ls2nud43	139	17	and	and	CC
cord-355413-ls2nud43	139	18	Malkin	Malkin	NNP
cord-355413-ls2nud43	139	19	,	,	,
cord-355413-ls2nud43	139	20	1999	1999	CD
cord-355413-ls2nud43	139	21	;	;	:
cord-355413-ls2nud43	139	22	Whitley	Whitley	NNP
cord-355413-ls2nud43	139	23	,	,	,
cord-355413-ls2nud43	139	24	2002	2002	CD
cord-355413-ls2nud43	139	25	)	)	-RRB-
cord-355413-ls2nud43	139	26	.	.	.
cord-355413-ls2nud43	140	1	The	the	DT
cord-355413-ls2nud43	140	2	transmission	transmission	NN
cord-355413-ls2nud43	140	3	of	of	IN
cord-355413-ls2nud43	140	4	HSV-2	HSV-2	NNP
cord-355413-ls2nud43	140	5	in	in	IN
cord-355413-ls2nud43	140	6	the	the	DT
cord-355413-ls2nud43	140	7	human	human	JJ
cord-355413-ls2nud43	140	8	population	population	NN
cord-355413-ls2nud43	140	9	includes	include	VBZ
cord-355413-ls2nud43	140	10	asymptomatic	asymptomatic	JJ
cord-355413-ls2nud43	140	11	shedding	shedding	NN
cord-355413-ls2nud43	140	12	of	of	IN
cord-355413-ls2nud43	140	13	the	the	DT
cord-355413-ls2nud43	140	14	virus	virus	NN
cord-355413-ls2nud43	140	15	even	even	RB
cord-355413-ls2nud43	140	16	in	in	IN
cord-355413-ls2nud43	140	17	the	the	DT
cord-355413-ls2nud43	140	18	presence	presence	NN
cord-355413-ls2nud43	140	19	of	of	IN
cord-355413-ls2nud43	140	20	CD8	CD8	NNP
cord-355413-ls2nud43	140	21			NNP
cord-355413-ls2nud43	140	22	cytotoxic	cytotoxic	JJ
cord-355413-ls2nud43	140	23	T	T	NNP
cord-355413-ls2nud43	140	24	lymphocytes	lymphocyte	NNS
cord-355413-ls2nud43	140	25	and	and	CC
cord-355413-ls2nud43	140	26	the	the	DT
cord-355413-ls2nud43	140	27	production	production	NN
cord-355413-ls2nud43	140	28	of	of	IN
cord-355413-ls2nud43	140	29	a	a	DT
cord-355413-ls2nud43	140	30	viral	viral	JJ
cord-355413-ls2nud43	140	31	glycoprotein	glycoprotein	NN
cord-355413-ls2nud43	140	32	that	that	WDT
cord-355413-ls2nud43	140	33	indirectly	indirectly	RB
cord-355413-ls2nud43	140	34	elicits	elicit	VBZ
cord-355413-ls2nud43	140	35	NK	NK	NNP
cord-355413-ls2nud43	140	36	cell	cell	NN
cord-355413-ls2nud43	140	37	death	death	NN
cord-355413-ls2nud43	141	1	(	(	-LRB-
cord-355413-ls2nud43	141	2	Bellner	Bellner	NNP
cord-355413-ls2nud43	141	3	et	et	NNP
cord-355413-ls2nud43	141	4	al	al	NNP
cord-355413-ls2nud43	141	5	.	.	.
cord-355413-ls2nud43	142	1	,	,	,
cord-355413-ls2nud43	142	2	2005	2005	CD
cord-355413-ls2nud43	142	3	;	;	:
cord-355413-ls2nud43	142	4	Posavad	Posavad	NNP
cord-355413-ls2nud43	142	5	et	et	NNP
cord-355413-ls2nud43	142	6	al	al	NNP
cord-355413-ls2nud43	142	7	.	.	NNP
cord-355413-ls2nud43	142	8	,	,	,
cord-355413-ls2nud43	142	9	2000	2000	CD
cord-355413-ls2nud43	142	10	;	;	:
cord-355413-ls2nud43	143	1	Wald	Wald	NNP
cord-355413-ls2nud43	143	2	et	et	NNP
cord-355413-ls2nud43	143	3	al	al	NNP
cord-355413-ls2nud43	143	4	.	.	NNP
cord-355413-ls2nud43	143	5	,	,	,
cord-355413-ls2nud43	143	6	2000	2000	CD
cord-355413-ls2nud43	143	7	)	)	-RRB-
cord-355413-ls2nud43	143	8	.	.	.
cord-355413-ls2nud43	144	1	In	in	IN
cord-355413-ls2nud43	144	2	a	a	DT
cord-355413-ls2nud43	144	3	mouse	mouse	NN
cord-355413-ls2nud43	144	4	model	model	NN
cord-355413-ls2nud43	144	5	of	of	IN
cord-355413-ls2nud43	144	6	HSV-2	hsv-2	JJ
cord-355413-ls2nud43	144	7	infection	infection	NN
cord-355413-ls2nud43	144	8	,	,	,
cord-355413-ls2nud43	144	9	it	-PRON-	PRP
cord-355413-ls2nud43	144	10	was	be	VBD
cord-355413-ls2nud43	144	11	shown	show	VBN
cord-355413-ls2nud43	144	12	that	that	IN
cord-355413-ls2nud43	144	13	mice	mouse	NNS
cord-355413-ls2nud43	144	14	deficient	deficient	JJ
cord-355413-ls2nud43	144	15	in	in	IN
cord-355413-ls2nud43	144	16	CCR5	CCR5	NNP
cord-355413-ls2nud43	144	17	(	(	-LRB-
cord-355413-ls2nud43	144	18	CCR5	ccr5	JJ
cord-355413-ls2nud43	144	19	/	/	NNS
cord-355413-ls2nud43	144	20	)	)	-RRB-
cord-355413-ls2nud43	144	21	displayed	display	VBD
cord-355413-ls2nud43	144	22	a	a	DT
cord-355413-ls2nud43	144	23	significant	significant	JJ
cord-355413-ls2nud43	144	24	reduction	reduction	NN
cord-355413-ls2nud43	144	25	in	in	IN
cord-355413-ls2nud43	144	26	cumulative	cumulative	JJ
cord-355413-ls2nud43	144	27	survival	survival	NN
cord-355413-ls2nud43	144	28	following	follow	VBG
cord-355413-ls2nud43	144	29	infection	infection	NN
cord-355413-ls2nud43	144	30	in	in	IN
cord-355413-ls2nud43	144	31	comparison	comparison	NN
cord-355413-ls2nud43	144	32	with	with	IN
cord-355413-ls2nud43	144	33	wild	wild	JJ
cord-355413-ls2nud43	144	34	-	-	HYPH
cord-355413-ls2nud43	144	35	type	type	NN
cord-355413-ls2nud43	144	36	HSV-2-infected	hsv-2-infected	JJ
cord-355413-ls2nud43	144	37	controls	control	NNS
cord-355413-ls2nud43	144	38	.	.	.
cord-355413-ls2nud43	145	1	Associated	associate	VBN
cord-355413-ls2nud43	145	2	with	with	IN
cord-355413-ls2nud43	145	3	decreased	decreased	JJ
cord-355413-ls2nud43	145	4	resistance	resistance	NN
cord-355413-ls2nud43	145	5	to	to	IN
cord-355413-ls2nud43	145	6	viral	viral	JJ
cord-355413-ls2nud43	145	7	infection	infection	NN
cord-355413-ls2nud43	145	8	,	,	,
cord-355413-ls2nud43	145	9	CCR5	ccr5	JJ
cord-355413-ls2nud43	145	10	/	/	NNS
cord-355413-ls2nud43	145	11	mice	mouse	NNS
cord-355413-ls2nud43	145	12	yielded	yield	VBD
cord-355413-ls2nud43	145	13	significantly	significantly	RB
cord-355413-ls2nud43	145	14	more	more	JJR
cord-355413-ls2nud43	145	15	virus	virus	NN
cord-355413-ls2nud43	145	16	and	and	CC
cord-355413-ls2nud43	145	17	expressed	express	VBD
cord-355413-ls2nud43	145	18	higher	high	JJR
cord-355413-ls2nud43	145	19	levels	level	NNS
cord-355413-ls2nud43	145	20	of	of	IN
cord-355413-ls2nud43	145	21	tumour	tumour	NN
cord-355413-ls2nud43	145	22	necrosis	necrosis	NN
cord-355413-ls2nud43	145	23	factor	factor	NN
cord-355413-ls2nud43	145	24	alpha	alpha	NN
cord-355413-ls2nud43	145	25	(	(	-LRB-
cord-355413-ls2nud43	145	26	TNF-	TNF-	NNP
cord-355413-ls2nud43	145	27	)	)	-RRB-
cord-355413-ls2nud43	145	28	,	,	,
cord-355413-ls2nud43	145	29	CXCL1	CXCL1	NNP
cord-355413-ls2nud43	145	30	,	,	,
cord-355413-ls2nud43	145	31	CCL2	CCL2	NNP
cord-355413-ls2nud43	145	32	,	,	,
cord-355413-ls2nud43	145	33	CCL3	CCL3	NNP
cord-355413-ls2nud43	145	34	and	and	CC
cord-355413-ls2nud43	145	35	CCL5	CCL5	NNP
cord-355413-ls2nud43	145	36	in	in	IN
cord-355413-ls2nud43	145	37	the	the	DT
cord-355413-ls2nud43	145	38	vagina	vagina	NN
cord-355413-ls2nud43	145	39	,	,	,
cord-355413-ls2nud43	145	40	spinal	spinal	JJ
cord-355413-ls2nud43	145	41	cord	cord	NN
cord-355413-ls2nud43	145	42	,	,	,
cord-355413-ls2nud43	145	43	and/or	and/or	CC
cord-355413-ls2nud43	145	44	brain	brain	NN
cord-355413-ls2nud43	145	45	stem	stem	NN
cord-355413-ls2nud43	145	46	than	than	IN
cord-355413-ls2nud43	145	47	did	do	VBD
cord-355413-ls2nud43	145	48	wild	wild	JJ
cord-355413-ls2nud43	145	49	-	-	HYPH
cord-355413-ls2nud43	145	50	type	type	NN
cord-355413-ls2nud43	145	51	mice	mouse	NNS
cord-355413-ls2nud43	145	52	.	.	.
cord-355413-ls2nud43	146	1	In	in	IN
cord-355413-ls2nud43	146	2	addition	addition	NN
cord-355413-ls2nud43	146	3	,	,	,
cord-355413-ls2nud43	146	4	when	when	WRB
cord-355413-ls2nud43	146	5	comparing	compare	VBG
cord-355413-ls2nud43	146	6	wildtype	wildtype	JJ
cord-355413-ls2nud43	146	7	HSV-2-infected	hsv-2-infected	JJ
cord-355413-ls2nud43	146	8	mice	mouse	NNS
cord-355413-ls2nud43	146	9	with	with	IN
cord-355413-ls2nud43	146	10	CCR5	CCR5	NNP
cord-355413-ls2nud43	146	11	/	/	NNS
cord-355413-ls2nud43	146	12	mice	mouse	NNS
cord-355413-ls2nud43	146	13	prior	prior	RB
cord-355413-ls2nud43	146	14	to	to	IN
cord-355413-ls2nud43	146	15	or	or	CC
cord-355413-ls2nud43	146	16	after	after	IN
cord-355413-ls2nud43	146	17	infection	infection	NN
cord-355413-ls2nud43	146	18	,	,	,
cord-355413-ls2nud43	146	19	there	there	EX
cord-355413-ls2nud43	146	20	were	be	VBD
cord-355413-ls2nud43	146	21	significantly	significantly	RB
cord-355413-ls2nud43	146	22	more	more	JJR
cord-355413-ls2nud43	146	23	NK	NK	NNP
cord-355413-ls2nud43	146	24	cells	cell	NNS
cord-355413-ls2nud43	146	25	(	(	-LRB-
cord-355413-ls2nud43	147	1	NK1.1	NK1.1	NNP
cord-355413-ls2nud43	147	2			CD
cord-355413-ls2nud43	148	1	CD3	CD3	NNP
cord-355413-ls2nud43	148	2			NNP
cord-355413-ls2nud43	148	3	)	)	-RRB-
cord-355413-ls2nud43	149	1	residing	reside	VBG
cord-355413-ls2nud43	149	2	in	in	IN
cord-355413-ls2nud43	149	3	the	the	DT
cord-355413-ls2nud43	149	4	brain	brain	NN
cord-355413-ls2nud43	149	5	stem	stem	NN
cord-355413-ls2nud43	149	6	and	and	CC
cord-355413-ls2nud43	149	7	spleen	spleen	NNS
cord-355413-ls2nud43	149	8	of	of	IN
cord-355413-ls2nud43	149	9	infected	infected	JJ
cord-355413-ls2nud43	149	10	wild	wild	JJ
cord-355413-ls2nud43	149	11	-	-	HYPH
cord-355413-ls2nud43	149	12	type	type	NN
cord-355413-ls2nud43	149	13	mice	mouse	NNS
cord-355413-ls2nud43	149	14	.	.	.
cord-355413-ls2nud43	150	1	Functionally	functionally	RB
cord-355413-ls2nud43	150	2	,	,	,
cord-355413-ls2nud43	150	3	NK	NK	NNP
cord-355413-ls2nud43	150	4	activity	activity	NN
cord-355413-ls2nud43	150	5	from	from	IN
cord-355413-ls2nud43	150	6	cells	cell	NNS
cord-355413-ls2nud43	150	7	isolated	isolate	VBN
cord-355413-ls2nud43	150	8	from	from	IN
cord-355413-ls2nud43	150	9	the	the	DT
cord-355413-ls2nud43	150	10	brain	brain	NN
cord-355413-ls2nud43	150	11	stem	stem	NN
cord-355413-ls2nud43	150	12	of	of	IN
cord-355413-ls2nud43	150	13	HSV-2-infected	hsv-2-infected	JJ
cord-355413-ls2nud43	150	14	wild	wild	JJ
cord-355413-ls2nud43	150	15	-	-	HYPH
cord-355413-ls2nud43	150	16	type	type	NN
cord-355413-ls2nud43	150	17	mice	mice	NN
cord-355413-ls2nud43	150	18	was	be	VBD
cord-355413-ls2nud43	150	19	greater	great	JJR
cord-355413-ls2nud43	150	20	than	than	IN
cord-355413-ls2nud43	150	21	that	that	DT
cord-355413-ls2nud43	150	22	from	from	IN
cord-355413-ls2nud43	150	23	HSV-2-infected	HSV-2-infected	NNP
cord-355413-ls2nud43	150	24	CCR5	CCR5	NNP
cord-355413-ls2nud43	150	25	/	/	NNS
cord-355413-ls2nud43	150	26	mice	mouse	NNS
cord-355413-ls2nud43	150	27	.	.	.
cord-355413-ls2nud43	151	1	Further	further	RB
cord-355413-ls2nud43	151	2	,	,	,
cord-355413-ls2nud43	151	3	antibody	antibody	NN
cord-355413-ls2nud43	151	4	-	-	HYPH
cord-355413-ls2nud43	151	5	mediated	mediate	VBN
cord-355413-ls2nud43	151	6	depletion	depletion	NN
cord-355413-ls2nud43	151	7	of	of	IN
cord-355413-ls2nud43	151	8	NK	NK	NNP
cord-355413-ls2nud43	151	9	cells	cell	NNS
cord-355413-ls2nud43	151	10	resulted	result	VBD
cord-355413-ls2nud43	151	11	in	in	IN
cord-355413-ls2nud43	151	12	an	an	DT
cord-355413-ls2nud43	151	13	increase	increase	NN
cord-355413-ls2nud43	151	14	in	in	IN
cord-355413-ls2nud43	151	15	HSV-2	hsv-2	JJ
cord-355413-ls2nud43	151	16	levels	level	NNS
cord-355413-ls2nud43	151	17	in	in	IN
cord-355413-ls2nud43	151	18	the	the	DT
cord-355413-ls2nud43	151	19	vaginal	vaginal	JJ
cord-355413-ls2nud43	151	20	,	,	,
cord-355413-ls2nud43	151	21	spinal	spinal	JJ
cord-355413-ls2nud43	151	22	cord	cord	NN
cord-355413-ls2nud43	151	23	and	and	CC
cord-355413-ls2nud43	151	24	brain	brain	NN
cord-355413-ls2nud43	151	25	stem	stem	NN
cord-355413-ls2nud43	151	26	tissue	tissue	NN
cord-355413-ls2nud43	151	27	of	of	IN
cord-355413-ls2nud43	151	28	wild	wild	JJ
cord-355413-ls2nud43	151	29	-	-	HYPH
cord-355413-ls2nud43	151	30	type	type	NN
cord-355413-ls2nud43	151	31	mice	mouse	NNS
cord-355413-ls2nud43	151	32	but	but	CC
cord-355413-ls2nud43	151	33	not	not	RB
cord-355413-ls2nud43	151	34	CCR5	ccr5	JJ
cord-355413-ls2nud43	151	35	/	/	NNS
cord-355413-ls2nud43	151	36	mice	mouse	NNS
cord-355413-ls2nud43	151	37	(	(	-LRB-
cord-355413-ls2nud43	151	38	Kveberg	Kveberg	NNP
cord-355413-ls2nud43	151	39	et	et	NNP
cord-355413-ls2nud43	151	40	al	al	NNP
cord-355413-ls2nud43	151	41	.	.	NNP
cord-355413-ls2nud43	151	42	,	,	,
cord-355413-ls2nud43	151	43	2002	2002	CD
cord-355413-ls2nud43	151	44	)	)	-RRB-
cord-355413-ls2nud43	151	45	.	.	.
cord-355413-ls2nud43	152	1	Collectively	collectively	RB
cord-355413-ls2nud43	152	2	,	,	,
cord-355413-ls2nud43	152	3	the	the	DT
cord-355413-ls2nud43	152	4	absence	absence	NN
cord-355413-ls2nud43	152	5	of	of	IN
cord-355413-ls2nud43	152	6	CCR5	CCR5	NNP
cord-355413-ls2nud43	152	7	expression	expression	NN
cord-355413-ls2nud43	152	8	significantly	significantly	RB
cord-355413-ls2nud43	152	9	impacts	impact	VBZ
cord-355413-ls2nud43	152	10	the	the	DT
cord-355413-ls2nud43	152	11	ability	ability	NN
cord-355413-ls2nud43	152	12	of	of	IN
cord-355413-ls2nud43	152	13	the	the	DT
cord-355413-ls2nud43	152	14	host	host	NN
cord-355413-ls2nud43	152	15	to	to	TO
cord-355413-ls2nud43	152	16	control	control	VB
cord-355413-ls2nud43	152	17	genital	genital	JJ
cord-355413-ls2nud43	152	18	HSV-2	hsv-2	JJ
cord-355413-ls2nud43	152	19	infection	infection	NN
cord-355413-ls2nud43	152	20	,	,	,
cord-355413-ls2nud43	152	21	inflammation	inflammation	NN
cord-355413-ls2nud43	152	22	and	and	CC
cord-355413-ls2nud43	152	23	spread	spread	VBD
cord-355413-ls2nud43	152	24	associated	associate	VBN
cord-355413-ls2nud43	152	25	with	with	IN
cord-355413-ls2nud43	152	26	a	a	DT
cord-355413-ls2nud43	152	27	specific	specific	JJ
cord-355413-ls2nud43	152	28	reduction	reduction	NN
cord-355413-ls2nud43	152	29	in	in	IN
cord-355413-ls2nud43	152	30	NK	NK	NNP
cord-355413-ls2nud43	152	31	cell	cell	NN
cord-355413-ls2nud43	152	32	expansion	expansion	NN
cord-355413-ls2nud43	152	33	,	,	,
cord-355413-ls2nud43	152	34	infiltration	infiltration	NN
cord-355413-ls2nud43	152	35	and	and	CC
cord-355413-ls2nud43	152	36	activity	activity	NN
cord-355413-ls2nud43	152	37	in	in	IN
cord-355413-ls2nud43	152	38	the	the	DT
cord-355413-ls2nud43	152	39	nervous	nervous	JJ
cord-355413-ls2nud43	152	40	system	system	NN
cord-355413-ls2nud43	152	41	.	.	.
cord-355413-ls2nud43	153	1	Congenital	congenital	JJ
cord-355413-ls2nud43	153	2	toxoplasmosis	toxoplasmosis	NN
cord-355413-ls2nud43	153	3	poses	pose	VBZ
cord-355413-ls2nud43	153	4	a	a	DT
cord-355413-ls2nud43	153	5	public	public	JJ
cord-355413-ls2nud43	153	6	health	health	NN
cord-355413-ls2nud43	153	7	problem	problem	NN
cord-355413-ls2nud43	153	8	,	,	,
cord-355413-ls2nud43	153	9	being	be	VBG
cord-355413-ls2nud43	153	10	capable	capable	JJ
cord-355413-ls2nud43	153	11	of	of	IN
cord-355413-ls2nud43	153	12	causing	cause	VBG
cord-355413-ls2nud43	153	13	foetal	foetal	JJ
cord-355413-ls2nud43	153	14	death	death	NN
cord-355413-ls2nud43	153	15	and	and	CC
cord-355413-ls2nud43	153	16	ocular	ocular	JJ
cord-355413-ls2nud43	153	17	and	and	CC
cord-355413-ls2nud43	153	18	neurological	neurological	JJ
cord-355413-ls2nud43	153	19	sequelae	sequela	NNS
cord-355413-ls2nud43	153	20	in	in	IN
cord-355413-ls2nud43	153	21	congenitally	congenitally	RB
cord-355413-ls2nud43	153	22	infected	infected	JJ
cord-355413-ls2nud43	153	23	children	child	NNS
cord-355413-ls2nud43	153	24	.	.	.
cord-355413-ls2nud43	154	1	Congenital	congenital	JJ
cord-355413-ls2nud43	154	2	infection	infection	NN
cord-355413-ls2nud43	154	3	occurs	occur	VBZ
cord-355413-ls2nud43	154	4	only	only	RB
cord-355413-ls2nud43	154	5	when	when	WRB
cord-355413-ls2nud43	154	6	mothers	mother	NNS
cord-355413-ls2nud43	154	7	first	first	RB
cord-355413-ls2nud43	154	8	encounter	encounter	VBP
cord-355413-ls2nud43	154	9	Toxoplasma	toxoplasma	NN
cord-355413-ls2nud43	154	10	gondii	gondii	NN
cord-355413-ls2nud43	154	11	(	(	-LRB-
cord-355413-ls2nud43	154	12	T.	t.	NN
cord-355413-ls2nud43	154	13	gondii	gondii	NNP
cord-355413-ls2nud43	154	14	)	)	-RRB-
cord-355413-ls2nud43	154	15	during	during	IN
cord-355413-ls2nud43	154	16	pregnancy	pregnancy	NN
cord-355413-ls2nud43	155	1	(	(	-LRB-
cord-355413-ls2nud43	155	2	Remington	Remington	NNP
cord-355413-ls2nud43	155	3	et	et	FW
cord-355413-ls2nud43	155	4	al	al	NNP
cord-355413-ls2nud43	155	5	.	.	.
cord-355413-ls2nud43	156	1	,	,	,
cord-355413-ls2nud43	156	2	1994	1994	CD
cord-355413-ls2nud43	156	3	;	;	:
cord-355413-ls2nud43	156	4	Roberts	Roberts	NNP
cord-355413-ls2nud43	156	5	and	and	CC
cord-355413-ls2nud43	156	6	Alexander	Alexander	NNP
cord-355413-ls2nud43	156	7	,	,	,
cord-355413-ls2nud43	156	8	1992	1992	CD
cord-355413-ls2nud43	156	9	)	)	-RRB-
cord-355413-ls2nud43	156	10	.	.	.
cord-355413-ls2nud43	157	1	Resistance	resistance	NN
cord-355413-ls2nud43	157	2	to	to	IN
cord-355413-ls2nud43	157	3	T.	t.	NN
cord-355413-ls2nud43	157	4	gondii	gondii	NNP
cord-355413-ls2nud43	157	5	is	be	VBZ
cord-355413-ls2nud43	157	6	mainly	mainly	RB
cord-355413-ls2nud43	157	7	mediated	mediate	VBN
cord-355413-ls2nud43	157	8	by	by	IN
cord-355413-ls2nud43	157	9	type	type	NN
cord-355413-ls2nud43	157	10	1	1	CD
cord-355413-ls2nud43	157	11	cytokines	cytokine	NNS
cord-355413-ls2nud43	157	12	,	,	,
cord-355413-ls2nud43	157	13	such	such	JJ
cord-355413-ls2nud43	157	14	as	as	IN
cord-355413-ls2nud43	157	15	IFN-	IFN-	NNP
cord-355413-ls2nud43	157	16	and	and	CC
cord-355413-ls2nud43	157	17	interleukin	interleukin	NN
cord-355413-ls2nud43	157	18	2	2	CD
cord-355413-ls2nud43	157	19	(	(	-LRB-
cord-355413-ls2nud43	157	20	IL-2	IL-2	NNP
cord-355413-ls2nud43	157	21	)	)	-RRB-
cord-355413-ls2nud43	157	22	,	,	,
cord-355413-ls2nud43	157	23	whereas	whereas	IN
cord-355413-ls2nud43	157	24	type	type	NN
cord-355413-ls2nud43	157	25	2	2	CD
cord-355413-ls2nud43	157	26	cytokines	cytokine	NNS
cord-355413-ls2nud43	157	27	,	,	,
cord-355413-ls2nud43	157	28	such	such	JJ
cord-355413-ls2nud43	157	29	as	as	IN
cord-355413-ls2nud43	157	30	IL-4	IL-4	NNP
cord-355413-ls2nud43	157	31	and	and	CC
cord-355413-ls2nud43	157	32	IL-10	IL-10	NNP
cord-355413-ls2nud43	157	33	,	,	,
cord-355413-ls2nud43	157	34	are	be	VBP
cord-355413-ls2nud43	157	35	associated	associate	VBN
cord-355413-ls2nud43	157	36	with	with	IN
cord-355413-ls2nud43	157	37	increased	increase	VBN
cord-355413-ls2nud43	157	38	susceptibility	susceptibility	NN
cord-355413-ls2nud43	157	39	to	to	IN
cord-355413-ls2nud43	157	40	infection	infection	NN
cord-355413-ls2nud43	157	41	(	(	-LRB-
cord-355413-ls2nud43	158	1	Hunter	Hunter	NNP
cord-355413-ls2nud43	158	2	et	et	NNP
cord-355413-ls2nud43	158	3	al	al	NNP
cord-355413-ls2nud43	158	4	.	.	.
cord-355413-ls2nud43	159	1	,	,	,
cord-355413-ls2nud43	159	2	1996	1996	CD
cord-355413-ls2nud43	159	3	;	;	:
cord-355413-ls2nud43	159	4	Khan	Khan	NNP
cord-355413-ls2nud43	159	5	et	et	NNP
cord-355413-ls2nud43	159	6	al	al	NNP
cord-355413-ls2nud43	159	7	.	.	NNP
cord-355413-ls2nud43	159	8	,	,	,
cord-355413-ls2nud43	159	9	1994	1994	CD
cord-355413-ls2nud43	159	10	)	)	-RRB-
cord-355413-ls2nud43	159	11	.	.	.
cord-355413-ls2nud43	160	1	Susceptibility	susceptibility	NN
cord-355413-ls2nud43	160	2	of	of	IN
cord-355413-ls2nud43	160	3	the	the	DT
cord-355413-ls2nud43	160	4	pregnant	pregnant	JJ
cord-355413-ls2nud43	160	5	host	host	NN
cord-355413-ls2nud43	160	6	to	to	IN
cord-355413-ls2nud43	160	7	toxoplasmosis	toxoplasmosis	NN
cord-355413-ls2nud43	160	8	may	may	MD
cord-355413-ls2nud43	160	9	be	be	VB
cord-355413-ls2nud43	160	10	attributable	attributable	JJ
cord-355413-ls2nud43	160	11	to	to	IN
cord-355413-ls2nud43	160	12	a	a	DT
cord-355413-ls2nud43	160	13	type	type	NN
cord-355413-ls2nud43	160	14	2-cytokine	2-cytokine	CD
cord-355413-ls2nud43	160	15	bias	bias	NN
cord-355413-ls2nud43	160	16	that	that	WDT
cord-355413-ls2nud43	160	17	is	be	VBZ
cord-355413-ls2nud43	160	18	maintained	maintain	VBN
cord-355413-ls2nud43	160	19	during	during	IN
cord-355413-ls2nud43	160	20	gestation	gestation	NN
cord-355413-ls2nud43	161	1	(	(	-LRB-
cord-355413-ls2nud43	161	2	Shirahata	Shirahata	NNP
cord-355413-ls2nud43	161	3	et	et	NNP
cord-355413-ls2nud43	161	4	al	al	NNP
cord-355413-ls2nud43	161	5	.	.	NNP
cord-355413-ls2nud43	161	6	,	,	,
cord-355413-ls2nud43	161	7	1992	1992	CD
cord-355413-ls2nud43	161	8	)	)	-RRB-
cord-355413-ls2nud43	161	9	.	.	.
cord-355413-ls2nud43	162	1	Cell	cell	NN
cord-355413-ls2nud43	162	2	-	-	HYPH
cord-355413-ls2nud43	162	3	mediated	mediate	VBN
cord-355413-ls2nud43	162	4	immune	immune	JJ
cord-355413-ls2nud43	162	5	responses	response	NNS
cord-355413-ls2nud43	162	6	involving	involve	VBG
cord-355413-ls2nud43	162	7	CD4	CD4	NNP
cord-355413-ls2nud43	162	8	and	and	CC
cord-355413-ls2nud43	162	9	CD8	CD8	NNP
cord-355413-ls2nud43	162	10	T	T	NNP
cord-355413-ls2nud43	162	11	cells	cell	NNS
cord-355413-ls2nud43	162	12	and	and	CC
cord-355413-ls2nud43	162	13	NK	NK	NNP
cord-355413-ls2nud43	162	14	cells	cell	NNS
cord-355413-ls2nud43	162	15	play	play	VBP
cord-355413-ls2nud43	162	16	a	a	DT
cord-355413-ls2nud43	162	17	protective	protective	JJ
cord-355413-ls2nud43	162	18	role	role	NN
cord-355413-ls2nud43	162	19	in	in	IN
cord-355413-ls2nud43	162	20	T.	t.	NN
cord-355413-ls2nud43	162	21	gondii	gondii	NNP
cord-355413-ls2nud43	162	22	primary	primary	JJ
cord-355413-ls2nud43	162	23	infection	infection	NN
cord-355413-ls2nud43	163	1	(	(	-LRB-
cord-355413-ls2nud43	163	2	Goldszmid	Goldszmid	NNP
cord-355413-ls2nud43	163	3	et	et	NNP
cord-355413-ls2nud43	163	4	al	al	NNP
cord-355413-ls2nud43	163	5	.	.	NNP
cord-355413-ls2nud43	163	6	,	,	,
cord-355413-ls2nud43	163	7	2007	2007	CD
cord-355413-ls2nud43	164	1	;	;	:
cord-355413-ls2nud43	164	2	Scharton	Scharton	NNP
cord-355413-ls2nud43	164	3	-	-	HYPH
cord-355413-ls2nud43	164	4	Kersten	Kersten	NNP
cord-355413-ls2nud43	164	5	et	et	NNP
cord-355413-ls2nud43	164	6	al	al	NNP
cord-355413-ls2nud43	164	7	.	.	NNP
cord-355413-ls2nud43	164	8	,	,	,
cord-355413-ls2nud43	164	9	1998	1998	CD
cord-355413-ls2nud43	164	10	;	;	:
cord-355413-ls2nud43	164	11	Scorza	Scorza	NNP
cord-355413-ls2nud43	164	12	et	et	NNP
cord-355413-ls2nud43	164	13	al	al	NNP
cord-355413-ls2nud43	164	14	.	.	NNP
cord-355413-ls2nud43	164	15	,	,	,
cord-355413-ls2nud43	164	16	2003	2003	CD
cord-355413-ls2nud43	164	17	;	;	:
cord-355413-ls2nud43	165	1	Scott	Scott	NNP
cord-355413-ls2nud43	165	2	and	and	CC
cord-355413-ls2nud43	165	3	Trinchieri	Trinchieri	NNP
cord-355413-ls2nud43	165	4	,	,	,
cord-355413-ls2nud43	165	5	1995	1995	CD
cord-355413-ls2nud43	165	6	;	;	:
cord-355413-ls2nud43	165	7	Subauste	Subauste	NNP
cord-355413-ls2nud43	165	8	et	et	NNP
cord-355413-ls2nud43	165	9	al	al	NNP
cord-355413-ls2nud43	165	10	.	.	NNP
cord-355413-ls2nud43	165	11	,	,	,
cord-355413-ls2nud43	165	12	1992	1992	CD
cord-355413-ls2nud43	165	13	)	)	-RRB-
cord-355413-ls2nud43	165	14	.	.	.
cord-355413-ls2nud43	166	1	To	to	TO
cord-355413-ls2nud43	166	2	clarify	clarify	VB
cord-355413-ls2nud43	166	3	the	the	DT
cord-355413-ls2nud43	166	4	roles	role	NNS
cord-355413-ls2nud43	166	5	of	of	IN
cord-355413-ls2nud43	166	6	NK	NK	NNP
cord-355413-ls2nud43	166	7	cells	cell	NNS
cord-355413-ls2nud43	166	8	and	and	CC
cord-355413-ls2nud43	166	9	IFN-	ifn-	NN
cord-355413-ls2nud43	166	10	in	in	IN
cord-355413-ls2nud43	166	11	protection	protection	NN
cord-355413-ls2nud43	166	12	against	against	IN
cord-355413-ls2nud43	166	13	primary	primary	JJ
cord-355413-ls2nud43	166	14	congenital	congenital	JJ
cord-355413-ls2nud43	166	15	toxoplasmosis	toxoplasmosis	NN
cord-355413-ls2nud43	166	16	,	,	,
cord-355413-ls2nud43	166	17	Abou	Abou	NNP
cord-355413-ls2nud43	166	18	-	-	HYPH
cord-355413-ls2nud43	166	19	Bacar	Bacar	NNP
cord-355413-ls2nud43	166	20	and	and	CC
cord-355413-ls2nud43	166	21	colleagues	colleague	NNS
cord-355413-ls2nud43	166	22	(	(	-LRB-
cord-355413-ls2nud43	166	23	2004	2004	CD
cord-355413-ls2nud43	166	24	)	)	-RRB-
cord-355413-ls2nud43	166	25	used	use	VBD
cord-355413-ls2nud43	166	26	recombination	recombination	NN
cord-355413-ls2nud43	166	27	activating	activate	VBG
cord-355413-ls2nud43	166	28	gene	gene	NN
cord-355413-ls2nud43	166	29	2	2	CD
cord-355413-ls2nud43	166	30	knockout	knockout	NN
cord-355413-ls2nud43	166	31	(	(	-LRB-
cord-355413-ls2nud43	166	32	KO	KO	NNP
cord-355413-ls2nud43	166	33	)	)	-RRB-
cord-355413-ls2nud43	166	34	(	(	-LRB-
cord-355413-ls2nud43	166	35	RAG-2	RAG-2	NNP
cord-355413-ls2nud43	166	36	/	/	NNS
cord-355413-ls2nud43	166	37	)	)	-RRB-
cord-355413-ls2nud43	166	38	mice	mouse	NNS
cord-355413-ls2nud43	166	39	,	,	,
cord-355413-ls2nud43	166	40	which	which	WDT
cord-355413-ls2nud43	166	41	lack	lack	VBP
cord-355413-ls2nud43	166	42	T	T	NNP
cord-355413-ls2nud43	166	43	and	and	CC
cord-355413-ls2nud43	166	44	B	b	NN
cord-355413-ls2nud43	166	45	lymphocytes	lymphocyte	NNS
cord-355413-ls2nud43	166	46	,	,	,
cord-355413-ls2nud43	166	47	in	in	IN
cord-355413-ls2nud43	166	48	comparison	comparison	NN
cord-355413-ls2nud43	166	49	with	with	IN
cord-355413-ls2nud43	166	50	the	the	DT
cord-355413-ls2nud43	166	51	wild	wild	JJ
cord-355413-ls2nud43	166	52	-	-	HYPH
cord-355413-ls2nud43	166	53	type	type	NN
cord-355413-ls2nud43	166	54	BALB	BALB	NNP
cord-355413-ls2nud43	166	55	/	/	SYM
cord-355413-ls2nud43	166	56	c	c	NNP
cord-355413-ls2nud43	166	57	model	model	NN
cord-355413-ls2nud43	166	58	.	.	.
cord-355413-ls2nud43	167	1	RAG-2	RAG-2	NNS
cord-355413-ls2nud43	167	2	/	/	NNS
cord-355413-ls2nud43	167	3	mice	mouse	NNS
cord-355413-ls2nud43	167	4	had	have	VBD
cord-355413-ls2nud43	167	5	a	a	DT
cord-355413-ls2nud43	167	6	significantly	significantly	RB
cord-355413-ls2nud43	167	7	lower	low	JJR
cord-355413-ls2nud43	167	8	risk	risk	NN
cord-355413-ls2nud43	167	9	of	of	IN
cord-355413-ls2nud43	167	10	foetal	foetal	JJ
cord-355413-ls2nud43	167	11	toxoplasmosis	toxoplasmosis	NN
cord-355413-ls2nud43	167	12	than	than	IN
cord-355413-ls2nud43	167	13	BALB	BALB	NNP
cord-355413-ls2nud43	167	14	/	/	SYM
cord-355413-ls2nud43	167	15	c	c	NN
cord-355413-ls2nud43	167	16	mice	mouse	NNS
cord-355413-ls2nud43	167	17	.	.	.
cord-355413-ls2nud43	168	1	This	this	DT
cord-355413-ls2nud43	168	2	protection	protection	NN
cord-355413-ls2nud43	168	3	was	be	VBD
cord-355413-ls2nud43	168	4	associated	associate	VBN
cord-355413-ls2nud43	168	5	with	with	IN
cord-355413-ls2nud43	168	6	an	an	DT
cord-355413-ls2nud43	168	7	increased	increase	VBN
cord-355413-ls2nud43	168	8	number	number	NN
cord-355413-ls2nud43	168	9	of	of	IN
cord-355413-ls2nud43	168	10	maternal	maternal	JJ
cord-355413-ls2nud43	168	11	NK	NK	NNP
cord-355413-ls2nud43	168	12	cells	cell	NNS
cord-355413-ls2nud43	168	13	,	,	,
cord-355413-ls2nud43	168	14	IFN-	ifn-	DT
cord-355413-ls2nud43	168	15	secretion	secretion	NN
cord-355413-ls2nud43	168	16	by	by	IN
cord-355413-ls2nud43	168	17	spleen	spleen	NN
cord-355413-ls2nud43	168	18	cells	cell	NNS
cord-355413-ls2nud43	168	19	,	,	,
cord-355413-ls2nud43	168	20	and	and	CC
cord-355413-ls2nud43	168	21	decreased	decrease	VBD
cord-355413-ls2nud43	168	22	parasitemia	parasitemia	NNP
cord-355413-ls2nud43	168	23	.	.	.
cord-355413-ls2nud43	169	1	In	in	IN
cord-355413-ls2nud43	169	2	the	the	DT
cord-355413-ls2nud43	169	3	RAG-2	RAG-2	NNP
cord-355413-ls2nud43	169	4	/	/	NNS
cord-355413-ls2nud43	169	5	mice	mouse	NNS
cord-355413-ls2nud43	169	6	,	,	,
cord-355413-ls2nud43	169	7	NK	NK	NNP
cord-355413-ls2nud43	169	8	cell	cell	NN
cord-355413-ls2nud43	169	9	depletion	depletion	NN
cord-355413-ls2nud43	169	10	increased	increase	VBD
cord-355413-ls2nud43	169	11	the	the	DT
cord-355413-ls2nud43	169	12	rate	rate	NN
cord-355413-ls2nud43	169	13	of	of	IN
cord-355413-ls2nud43	169	14	foetal	foetal	JJ
cord-355413-ls2nud43	169	15	infection	infection	NN
cord-355413-ls2nud43	169	16	.	.	.
cord-355413-ls2nud43	170	1	These	these	DT
cord-355413-ls2nud43	170	2	data	datum	NNS
cord-355413-ls2nud43	170	3	suggest	suggest	VBP
cord-355413-ls2nud43	170	4	that	that	IN
cord-355413-ls2nud43	170	5	a	a	DT
cord-355413-ls2nud43	170	6	partially	partially	RB
cord-355413-ls2nud43	170	7	protective	protective	JJ
cord-355413-ls2nud43	170	8	immunity	immunity	NN
cord-355413-ls2nud43	170	9	against	against	IN
cord-355413-ls2nud43	170	10	congenital	congenital	JJ
cord-355413-ls2nud43	170	11	toxoplasmosis	toxoplasmosis	NN
cord-355413-ls2nud43	170	12	is	be	VBZ
cord-355413-ls2nud43	170	13	achieved	achieve	VBN
cord-355413-ls2nud43	170	14	owing	owe	VBG
cord-355413-ls2nud43	170	15	to	to	IN
cord-355413-ls2nud43	170	16	the	the	DT
cord-355413-ls2nud43	170	17	increased	increase	VBN
cord-355413-ls2nud43	170	18	number	number	NN
cord-355413-ls2nud43	170	19	of	of	IN
cord-355413-ls2nud43	170	20	NK	NK	NNP
cord-355413-ls2nud43	170	21	cells	cell	NNS
cord-355413-ls2nud43	170	22	in	in	IN
cord-355413-ls2nud43	170	23	RAG-2	RAG-2	NNP
cord-355413-ls2nud43	170	24	/	/	NNS
cord-355413-ls2nud43	170	25	mice	mouse	NNS
cord-355413-ls2nud43	171	1	(	(	-LRB-
cord-355413-ls2nud43	171	2	Abou	Abou	NNP
cord-355413-ls2nud43	171	3	-	-	HYPH
cord-355413-ls2nud43	171	4	Bacar	Bacar	NNP
cord-355413-ls2nud43	171	5	et	et	FW
cord-355413-ls2nud43	171	6	al	al	NNP
cord-355413-ls2nud43	171	7	.	.	NNP
cord-355413-ls2nud43	171	8	,	,	,
cord-355413-ls2nud43	171	9	2004	2004	CD
cord-355413-ls2nud43	171	10	)	)	-RRB-
cord-355413-ls2nud43	171	11	.	.	.
cord-355413-ls2nud43	172	1	Protective	protective	JJ
cord-355413-ls2nud43	172	2	effect	effect	NN
cord-355413-ls2nud43	172	3	of	of	IN
cord-355413-ls2nud43	172	4	NK	NK	NNP
cord-355413-ls2nud43	172	5	cells	cell	NNS
cord-355413-ls2nud43	172	6	was	be	VBD
cord-355413-ls2nud43	172	7	confirmed	confirm	VBN
cord-355413-ls2nud43	172	8	in	in	IN
cord-355413-ls2nud43	172	9	another	another	DT
cord-355413-ls2nud43	172	10	study	study	NN
cord-355413-ls2nud43	172	11	using	use	VBG
cord-355413-ls2nud43	172	12	the	the	DT
cord-355413-ls2nud43	172	13	SCID	SCID	NNP
cord-355413-ls2nud43	172	14	model	model	NN
cord-355413-ls2nud43	172	15	(	(	-LRB-
cord-355413-ls2nud43	172	16	Kang	Kang	NNP
cord-355413-ls2nud43	172	17	and	and	CC
cord-355413-ls2nud43	172	18	Suzuki	Suzuki	NNP
cord-355413-ls2nud43	172	19	,	,	,
cord-355413-ls2nud43	172	20	2001	2001	CD
cord-355413-ls2nud43	172	21	)	)	-RRB-
cord-355413-ls2nud43	172	22	.	.	.
cord-355413-ls2nud43	173	1	The	the	DT
cord-355413-ls2nud43	173	2	innate	innate	JJ
cord-355413-ls2nud43	173	3	immune	immune	JJ
cord-355413-ls2nud43	173	4	system	system	NN
cord-355413-ls2nud43	173	5	plays	play	VBZ
cord-355413-ls2nud43	173	6	an	an	DT
cord-355413-ls2nud43	173	7	instrumental	instrumental	JJ
cord-355413-ls2nud43	173	8	role	role	NN
cord-355413-ls2nud43	173	9	in	in	IN
cord-355413-ls2nud43	173	10	generating	generate	VBG
cord-355413-ls2nud43	173	11	and	and	CC
cord-355413-ls2nud43	173	12	directing	direct	VBG
cord-355413-ls2nud43	173	13	the	the	DT
cord-355413-ls2nud43	173	14	adaptive	adaptive	JJ
cord-355413-ls2nud43	173	15	immune	immune	JJ
cord-355413-ls2nud43	173	16	responses	response	NNS
cord-355413-ls2nud43	173	17	(	(	-LRB-
cord-355413-ls2nud43	173	18	Shi	Shi	NNP
cord-355413-ls2nud43	173	19	et	et	FW
cord-355413-ls2nud43	173	20	al	al	NNP
cord-355413-ls2nud43	173	21	.	.	NNP
cord-355413-ls2nud43	173	22	,	,	,
cord-355413-ls2nud43	173	23	2001	2001	CD
cord-355413-ls2nud43	173	24	)	)	-RRB-
cord-355413-ls2nud43	173	25	.	.	.
cord-355413-ls2nud43	174	1	NK	NK	NNP
cord-355413-ls2nud43	174	2	cells	cell	NNS
cord-355413-ls2nud43	174	3	represent	represent	VBP
cord-355413-ls2nud43	174	4	a	a	DT
cord-355413-ls2nud43	174	5	critical	critical	JJ
cord-355413-ls2nud43	174	6	first	first	JJ
cord-355413-ls2nud43	174	7	line	line	NN
cord-355413-ls2nud43	174	8	of	of	IN
cord-355413-ls2nud43	174	9	defence	defence	NN
cord-355413-ls2nud43	174	10	against	against	IN
cord-355413-ls2nud43	174	11	malignant	malignant	JJ
cord-355413-ls2nud43	174	12	transformation	transformation	NN
cord-355413-ls2nud43	174	13	.	.	.
cord-355413-ls2nud43	175	1	Earlier	early	JJR
cord-355413-ls2nud43	175	2	results	result	NNS
cord-355413-ls2nud43	175	3	by	by	IN
cord-355413-ls2nud43	175	4	Karre	Karre	NNP
cord-355413-ls2nud43	175	5	and	and	CC
cord-355413-ls2nud43	175	6	Ljunggren	Ljunggren	NNP
cord-355413-ls2nud43	175	7	demonstrated	demonstrate	VBD
cord-355413-ls2nud43	175	8	that	that	IN
cord-355413-ls2nud43	175	9	NK	NK	NNP
cord-355413-ls2nud43	175	10	cells	cell	NNS
cord-355413-ls2nud43	175	11	can	can	MD
cord-355413-ls2nud43	175	12	preferentially	preferentially	RB
cord-355413-ls2nud43	175	13	kill	kill	VB
cord-355413-ls2nud43	175	14	and	and	CC
cord-355413-ls2nud43	175	15	reject	reject	VB
cord-355413-ls2nud43	175	16	cells	cell	NNS
cord-355413-ls2nud43	175	17	that	that	WDT
cord-355413-ls2nud43	175	18	fail	fail	VBP
cord-355413-ls2nud43	175	19	to	to	TO
cord-355413-ls2nud43	175	20	express	express	VB
cord-355413-ls2nud43	175	21	'	'	``
cord-355413-ls2nud43	175	22	self	self	NN
cord-355413-ls2nud43	175	23	'	'	''
cord-355413-ls2nud43	175	24	MHC	MHC	NNP
cord-355413-ls2nud43	175	25	class	class	NN
cord-355413-ls2nud43	176	1	I	-PRON-	PRP
cord-355413-ls2nud43	176	2	molecules	molecule	NNS
cord-355413-ls2nud43	177	1	(	(	-LRB-
cord-355413-ls2nud43	177	2	Karre	Karre	NNP
cord-355413-ls2nud43	177	3	et	et	FW
cord-355413-ls2nud43	177	4	al	al	NNP
cord-355413-ls2nud43	177	5	.	.	NNP
cord-355413-ls2nud43	177	6	,	,	,
cord-355413-ls2nud43	177	7	1986	1986	CD
cord-355413-ls2nud43	177	8	)	)	-RRB-
cord-355413-ls2nud43	177	9	.	.	.
cord-355413-ls2nud43	178	1	These	these	DT
cord-355413-ls2nud43	178	2	findings	finding	NNS
cord-355413-ls2nud43	178	3	led	lead	VBD
cord-355413-ls2nud43	178	4	to	to	IN
cord-355413-ls2nud43	178	5	the	the	DT
cord-355413-ls2nud43	178	6	formation	formation	NN
cord-355413-ls2nud43	178	7	of	of	IN
cord-355413-ls2nud43	178	8	the	the	DT
cord-355413-ls2nud43	178	9	famous	famous	JJ
cord-355413-ls2nud43	178	10	'	'	``
cord-355413-ls2nud43	178	11	missing	miss	VBG
cord-355413-ls2nud43	178	12	self	self	NN
cord-355413-ls2nud43	178	13	hypothesis	hypothesis	NN
cord-355413-ls2nud43	178	14	'	'	''
cord-355413-ls2nud43	178	15	(	(	-LRB-
cord-355413-ls2nud43	178	16	Ljunggren	Ljunggren	NNP
cord-355413-ls2nud43	178	17	and	and	CC
cord-355413-ls2nud43	178	18	Karre	Karre	NNP
cord-355413-ls2nud43	178	19	,	,	,
cord-355413-ls2nud43	178	20	1990	1990	CD
cord-355413-ls2nud43	178	21	)	)	-RRB-
cord-355413-ls2nud43	178	22	.	.	.
cord-355413-ls2nud43	179	1	Over	over	IN
cord-355413-ls2nud43	179	2	the	the	DT
cord-355413-ls2nud43	179	3	years	year	NNS
cord-355413-ls2nud43	179	4	,	,	,
cord-355413-ls2nud43	179	5	the	the	DT
cord-355413-ls2nud43	179	6	missing	miss	VBG
cord-355413-ls2nud43	179	7	self	self	NN
cord-355413-ls2nud43	179	8	hypothesis	hypothesis	NN
cord-355413-ls2nud43	179	9	has	have	VBZ
cord-355413-ls2nud43	179	10	been	be	VBN
cord-355413-ls2nud43	179	11	repeatedly	repeatedly	RB
cord-355413-ls2nud43	179	12	demonstrated	demonstrate	VBN
cord-355413-ls2nud43	179	13	in	in	IN
cord-355413-ls2nud43	179	14	a	a	DT
cord-355413-ls2nud43	179	15	variety	variety	NN
cord-355413-ls2nud43	179	16	of	of	IN
cord-355413-ls2nud43	179	17	experimental	experimental	JJ
cord-355413-ls2nud43	179	18	tumour	tumour	NN
cord-355413-ls2nud43	179	19	systems	system	NNS
cord-355413-ls2nud43	179	20	by	by	IN
cord-355413-ls2nud43	179	21	different	different	JJ
cord-355413-ls2nud43	179	22	groups	group	NNS
cord-355413-ls2nud43	179	23	of	of	IN
cord-355413-ls2nud43	179	24	investigators	investigator	NNS
cord-355413-ls2nud43	179	25	,	,	,
cord-355413-ls2nud43	179	26	and	and	CC
cord-355413-ls2nud43	179	27	a	a	DT
cord-355413-ls2nud43	179	28	number	number	NN
cord-355413-ls2nud43	179	29	of	of	IN
cord-355413-ls2nud43	179	30	molecular	molecular	JJ
cord-355413-ls2nud43	179	31	pathways	pathway	NNS
cord-355413-ls2nud43	179	32	governing	govern	VBG
cord-355413-ls2nud43	179	33	the	the	DT
cord-355413-ls2nud43	179	34	interactions	interaction	NNS
cord-355413-ls2nud43	179	35	of	of	IN
cord-355413-ls2nud43	179	36	NK	NK	NNP
cord-355413-ls2nud43	179	37	cell	cell	NN
cord-355413-ls2nud43	179	38	-	-	HYPH
cord-355413-ls2nud43	179	39	target	target	NN
cord-355413-ls2nud43	179	40	cells	cell	NNS
cord-355413-ls2nud43	179	41	have	have	VBP
cord-355413-ls2nud43	179	42	been	be	VBN
cord-355413-ls2nud43	179	43	revealed	reveal	VBN
cord-355413-ls2nud43	179	44	.	.	.
cord-355413-ls2nud43	180	1	Surveillance	surveillance	NN
cord-355413-ls2nud43	180	2	against	against	IN
cord-355413-ls2nud43	180	3	'	'	``
cord-355413-ls2nud43	180	4	missing	miss	VBG
cord-355413-ls2nud43	180	5	self	self	NN
cord-355413-ls2nud43	180	6	'	'	''
cord-355413-ls2nud43	180	7	may	may	MD
cord-355413-ls2nud43	180	8	thus	thus	RB
cord-355413-ls2nud43	180	9	be	be	VB
cord-355413-ls2nud43	180	10	one	one	CD
cord-355413-ls2nud43	180	11	,	,	,
cord-355413-ls2nud43	180	12	but	but	CC
cord-355413-ls2nud43	180	13	not	not	RB
cord-355413-ls2nud43	180	14	the	the	DT
cord-355413-ls2nud43	180	15	only	only	JJ
cord-355413-ls2nud43	180	16	function	function	NN
cord-355413-ls2nud43	180	17	of	of	IN
cord-355413-ls2nud43	180	18	NK	NK	NNP
cord-355413-ls2nud43	180	19	cells	cell	NNS
cord-355413-ls2nud43	180	20	(	(	-LRB-
cord-355413-ls2nud43	180	21	Ljunggren	Ljunggren	NNP
cord-355413-ls2nud43	180	22	and	and	CC
cord-355413-ls2nud43	180	23	Malmberg	Malmberg	NNP
cord-355413-ls2nud43	180	24	,	,	,
cord-355413-ls2nud43	180	25	2007	2007	CD
cord-355413-ls2nud43	180	26	)	)	-RRB-
cord-355413-ls2nud43	180	27	.	.	.
cord-355413-ls2nud43	181	1	Non	non	JJ
cord-355413-ls2nud43	181	2	-	-	JJ
cord-355413-ls2nud43	181	3	surgical	surgical	JJ
cord-355413-ls2nud43	181	4	resectable	resectable	JJ
cord-355413-ls2nud43	181	5	tumours	tumour	NNS
cord-355413-ls2nud43	181	6	within	within	IN
cord-355413-ls2nud43	181	7	the	the	DT
cord-355413-ls2nud43	181	8	CNS	CNS	NNP
cord-355413-ls2nud43	181	9	constitute	constitute	VBP
cord-355413-ls2nud43	181	10	significant	significant	JJ
cord-355413-ls2nud43	181	11	challenges	challenge	NNS
cord-355413-ls2nud43	181	12	for	for	IN
cord-355413-ls2nud43	181	13	physicians	physician	NNS
cord-355413-ls2nud43	181	14	.	.	.
cord-355413-ls2nud43	182	1	Furthermore	furthermore	RB
cord-355413-ls2nud43	182	2	,	,	,
cord-355413-ls2nud43	182	3	studies	study	NNS
cord-355413-ls2nud43	182	4	have	have	VBP
cord-355413-ls2nud43	182	5	documented	document	VBN
cord-355413-ls2nud43	182	6	frequent	frequent	JJ
cord-355413-ls2nud43	182	7	immune	immune	JJ
cord-355413-ls2nud43	182	8	system	system	NN
cord-355413-ls2nud43	182	9	defects	defect	NNS
cord-355413-ls2nud43	182	10	in	in	IN
cord-355413-ls2nud43	182	11	intracranial	intracranial	JJ
cord-355413-ls2nud43	182	12	tumour	tumour	NN
cord-355413-ls2nud43	182	13	-	-	HYPH
cord-355413-ls2nud43	182	14	bearing	bear	VBG
cord-355413-ls2nud43	182	15	patients	patient	NNS
cord-355413-ls2nud43	182	16	and	and	CC
cord-355413-ls2nud43	182	17	an	an	DT
cord-355413-ls2nud43	182	18	inability	inability	NN
cord-355413-ls2nud43	182	19	of	of	IN
cord-355413-ls2nud43	182	20	certain	certain	JJ
cord-355413-ls2nud43	182	21	lymphocyte	lymphocyte	NN
cord-355413-ls2nud43	182	22	subset	subset	VBN
cord-355413-ls2nud43	182	23	to	to	TO
cord-355413-ls2nud43	182	24	mediate	mediate	VB
cord-355413-ls2nud43	182	25	antitumour	antitumour	JJ
cord-355413-ls2nud43	182	26	effector	effector	NN
cord-355413-ls2nud43	182	27	functions	function	NNS
cord-355413-ls2nud43	182	28	in	in	IN
cord-355413-ls2nud43	182	29	the	the	DT
cord-355413-ls2nud43	182	30	CNS	CNS	NNP
cord-355413-ls2nud43	182	31	.	.	.
cord-355413-ls2nud43	183	1	Malignant	malignant	JJ
cord-355413-ls2nud43	183	2	melanoma	melanoma	NN
cord-355413-ls2nud43	183	3	is	be	VBZ
cord-355413-ls2nud43	183	4	notorious	notorious	JJ
cord-355413-ls2nud43	183	5	for	for	IN
cord-355413-ls2nud43	183	6	metastasis	metastasis	NN
cord-355413-ls2nud43	183	7	to	to	IN
cord-355413-ls2nud43	183	8	discrete	discrete	JJ
cord-355413-ls2nud43	183	9	locations	location	NNS
cord-355413-ls2nud43	183	10	such	such	JJ
cord-355413-ls2nud43	183	11	as	as	IN
cord-355413-ls2nud43	183	12	testis	testis	NN
cord-355413-ls2nud43	183	13	and	and	CC
cord-355413-ls2nud43	183	14	brain	brain	NN
cord-355413-ls2nud43	183	15	.	.	.
cord-355413-ls2nud43	184	1	Malignant	malignant	JJ
cord-355413-ls2nud43	184	2	melanoma	melanoma	NN
cord-355413-ls2nud43	184	3	is	be	VBZ
cord-355413-ls2nud43	184	4	the	the	DT
cord-355413-ls2nud43	184	5	third	third	JJ
cord-355413-ls2nud43	184	6	most	most	RBS
cord-355413-ls2nud43	184	7	common	common	JJ
cord-355413-ls2nud43	184	8	type	type	NN
cord-355413-ls2nud43	184	9	of	of	IN
cord-355413-ls2nud43	184	10	cancer	cancer	NN
cord-355413-ls2nud43	184	11	that	that	WDT
cord-355413-ls2nud43	184	12	metastasizes	metastasize	VBZ
cord-355413-ls2nud43	184	13	to	to	IN
cord-355413-ls2nud43	184	14	the	the	DT
cord-355413-ls2nud43	184	15	brain	brain	NN
cord-355413-ls2nud43	185	1	(	(	-LRB-
cord-355413-ls2nud43	185	2	Prins	Prins	NNP
cord-355413-ls2nud43	185	3	et	et	NNP
cord-355413-ls2nud43	185	4	al	al	NNP
cord-355413-ls2nud43	185	5	.	.	NNP
cord-355413-ls2nud43	185	6	,	,	,
cord-355413-ls2nud43	185	7	2006	2006	CD
cord-355413-ls2nud43	185	8	)	)	-RRB-
cord-355413-ls2nud43	185	9	,	,	,
cord-355413-ls2nud43	185	10	which	which	WDT
cord-355413-ls2nud43	185	11	presents	present	VBZ
cord-355413-ls2nud43	185	12	clinicians	clinician	NNS
cord-355413-ls2nud43	185	13	with	with	IN
cord-355413-ls2nud43	185	14	few	few	JJ
cord-355413-ls2nud43	185	15	treatment	treatment	NN
cord-355413-ls2nud43	185	16	options	option	NNS
cord-355413-ls2nud43	185	17	.	.	.
cord-355413-ls2nud43	186	1	Although	although	IN
cord-355413-ls2nud43	186	2	nearly	nearly	RB
cord-355413-ls2nud43	186	3	a	a	DT
cord-355413-ls2nud43	186	4	dozen	dozen	NN
cord-355413-ls2nud43	186	5	melanoma	melanoma	NN
cord-355413-ls2nud43	186	6	antigens	antigen	NNS
cord-355413-ls2nud43	186	7	specifically	specifically	RB
cord-355413-ls2nud43	186	8	recognized	recognize	VBN
cord-355413-ls2nud43	186	9	by	by	IN
cord-355413-ls2nud43	186	10	T	T	NNP
cord-355413-ls2nud43	186	11	cells	cell	NNS
cord-355413-ls2nud43	186	12	have	have	VBP
cord-355413-ls2nud43	186	13	been	be	VBN
cord-355413-ls2nud43	186	14	identified	identify	VBN
cord-355413-ls2nud43	186	15	,	,	,
cord-355413-ls2nud43	186	16	melanoma	melanoma	NN
cord-355413-ls2nud43	186	17	cells	cell	NNS
cord-355413-ls2nud43	186	18	are	be	VBP
cord-355413-ls2nud43	186	19	still	still	RB
cord-355413-ls2nud43	186	20	able	able	JJ
cord-355413-ls2nud43	186	21	to	to	TO
cord-355413-ls2nud43	186	22	avoid	avoid	VB
cord-355413-ls2nud43	186	23	immune	immune	JJ
cord-355413-ls2nud43	186	24	destruction	destruction	NN
cord-355413-ls2nud43	186	25	in	in	IN
cord-355413-ls2nud43	186	26	most	most	JJS
cord-355413-ls2nud43	186	27	instances	instance	NNS
cord-355413-ls2nud43	186	28	.	.	.
cord-355413-ls2nud43	187	1	Because	because	IN
cord-355413-ls2nud43	187	2	the	the	DT
cord-355413-ls2nud43	187	3	generation	generation	NN
cord-355413-ls2nud43	187	4	of	of	IN
cord-355413-ls2nud43	187	5	an	an	DT
cord-355413-ls2nud43	187	6	effective	effective	JJ
cord-355413-ls2nud43	187	7	antitumour	antitumour	JJ
cord-355413-ls2nud43	187	8	immune	immune	JJ
cord-355413-ls2nud43	187	9	response	response	NN
cord-355413-ls2nud43	187	10	requires	require	VBZ
cord-355413-ls2nud43	187	11	both	both	CC
cord-355413-ls2nud43	187	12	the	the	DT
cord-355413-ls2nud43	187	13	presence	presence	NN
cord-355413-ls2nud43	187	14	of	of	IN
cord-355413-ls2nud43	187	15	foreign	foreign	JJ
cord-355413-ls2nud43	187	16	antigen	antigen	NN
cord-355413-ls2nud43	187	17	and	and	CC
cord-355413-ls2nud43	187	18	a	a	DT
cord-355413-ls2nud43	187	19	costimulatory	costimulatory	NN
cord-355413-ls2nud43	187	20	molecule	molecule	NN
cord-355413-ls2nud43	187	21	or	or	CC
cord-355413-ls2nud43	187	22	signal	signal	NN
cord-355413-ls2nud43	187	23	,	,	,
cord-355413-ls2nud43	187	24	tumour	tumour	NN
cord-355413-ls2nud43	187	25	cells	cell	NNS
cord-355413-ls2nud43	187	26	displaying	display	VBG
cord-355413-ls2nud43	187	27	tumour	tumour	NN
cord-355413-ls2nud43	187	28	antigens	antigen	NNS
cord-355413-ls2nud43	187	29	may	may	MD
cord-355413-ls2nud43	187	30	avoid	avoid	VB
cord-355413-ls2nud43	187	31	immune	immune	JJ
cord-355413-ls2nud43	187	32	detection	detection	NN
cord-355413-ls2nud43	187	33	because	because	IN
cord-355413-ls2nud43	187	34	of	of	IN
cord-355413-ls2nud43	187	35	the	the	DT
cord-355413-ls2nud43	187	36	absence	absence	NN
cord-355413-ls2nud43	187	37	of	of	IN
cord-355413-ls2nud43	187	38	appropriate	appropriate	JJ
cord-355413-ls2nud43	187	39	costimulation	costimulation	NN
cord-355413-ls2nud43	187	40	.	.	.
cord-355413-ls2nud43	188	1	Thus	thus	RB
cord-355413-ls2nud43	188	2	,	,	,
cord-355413-ls2nud43	188	3	anti	anti	JJ
cord-355413-ls2nud43	188	4	-	-	JJ
cord-355413-ls2nud43	188	5	tumour	tumour	JJ
cord-355413-ls2nud43	188	6	immune	immune	JJ
cord-355413-ls2nud43	188	7	responses	response	NNS
cord-355413-ls2nud43	188	8	might	may	MD
cord-355413-ls2nud43	188	9	be	be	VB
cord-355413-ls2nud43	188	10	achieved	achieve	VBN
cord-355413-ls2nud43	188	11	by	by	IN
cord-355413-ls2nud43	188	12	more	more	RBR
cord-355413-ls2nud43	188	13	effective	effective	JJ
cord-355413-ls2nud43	188	14	local	local	JJ
cord-355413-ls2nud43	188	15	delivery	delivery	NN
cord-355413-ls2nud43	188	16	of	of	IN
cord-355413-ls2nud43	188	17	costimulatory	costimulatory	NN
cord-355413-ls2nud43	188	18	molecules	molecule	NNS
cord-355413-ls2nud43	188	19	.	.	.
cord-355413-ls2nud43	189	1	Activation	activation	NN
cord-355413-ls2nud43	189	2	and	and	CC
cord-355413-ls2nud43	189	3	expansion	expansion	NN
cord-355413-ls2nud43	189	4	of	of	IN
cord-355413-ls2nud43	189	5	NK	NK	NNP
cord-355413-ls2nud43	189	6	cells	cell	NNS
cord-355413-ls2nud43	189	7	may	may	MD
cord-355413-ls2nud43	189	8	independently	independently	RB
cord-355413-ls2nud43	189	9	lyse	lyse	VB
cord-355413-ls2nud43	189	10	tumour	tumour	NN
cord-355413-ls2nud43	189	11	cells	cell	NNS
cord-355413-ls2nud43	189	12	,	,	,
cord-355413-ls2nud43	189	13	or	or	CC
cord-355413-ls2nud43	189	14	provide	provide	VB
cord-355413-ls2nud43	189	15	T	t	NN
cord-355413-ls2nud43	189	16	cells	cell	NNS
cord-355413-ls2nud43	189	17	with	with	IN
cord-355413-ls2nud43	189	18	costimulatory	costimulatory	NN
cord-355413-ls2nud43	189	19	molecules	molecule	NNS
cord-355413-ls2nud43	189	20	including	include	VBG
cord-355413-ls2nud43	189	21	cytokines	cytokine	NNS
cord-355413-ls2nud43	189	22	,	,	,
cord-355413-ls2nud43	189	23	and	and	CC
cord-355413-ls2nud43	189	24	overall	overall	JJ
cord-355413-ls2nud43	189	25	enhance	enhance	VB
cord-355413-ls2nud43	189	26	antigen	antigen	NN
cord-355413-ls2nud43	189	27	presentation	presentation	NN
cord-355413-ls2nud43	189	28	to	to	IN
cord-355413-ls2nud43	189	29	T	t	NN
cord-355413-ls2nud43	189	30	cells	cell	NNS
cord-355413-ls2nud43	189	31	.	.	.
cord-355413-ls2nud43	190	1	Several	several	JJ
cord-355413-ls2nud43	190	2	attempts	attempt	NNS
cord-355413-ls2nud43	190	3	have	have	VBP
cord-355413-ls2nud43	190	4	been	be	VBN
cord-355413-ls2nud43	190	5	made	make	VBN
cord-355413-ls2nud43	190	6	in	in	IN
cord-355413-ls2nud43	190	7	an	an	DT
cord-355413-ls2nud43	190	8	effort	effort	NN
cord-355413-ls2nud43	190	9	to	to	TO
cord-355413-ls2nud43	190	10	use	use	VB
cord-355413-ls2nud43	190	11	NK	NK	NNP
cord-355413-ls2nud43	190	12	cells	cell	NNS
cord-355413-ls2nud43	190	13	to	to	TO
cord-355413-ls2nud43	190	14	target	target	VB
cord-355413-ls2nud43	190	15	CNS	cns	JJ
cord-355413-ls2nud43	190	16	melanoma	melanoma	NN
cord-355413-ls2nud43	190	17	.	.	.
cord-355413-ls2nud43	191	1	The	the	DT
cord-355413-ls2nud43	191	2	specific	specific	JJ
cord-355413-ls2nud43	191	3	receptor	receptor	NN
cord-355413-ls2nud43	191	4	for	for	IN
cord-355413-ls2nud43	191	5	IL-2	il-2	NN
cord-355413-ls2nud43	192	1	on	on	IN
cord-355413-ls2nud43	192	2	NK	NK	NNP
cord-355413-ls2nud43	192	3	cells	cell	NNS
cord-355413-ls2nud43	192	4	allows	allow	VBZ
cord-355413-ls2nud43	192	5	several	several	JJ
cord-355413-ls2nud43	192	6	approaches	approach	NNS
cord-355413-ls2nud43	192	7	to	to	TO
cord-355413-ls2nud43	192	8	deliver	deliver	VB
cord-355413-ls2nud43	192	9	IL-2	IL-2	NNP
cord-355413-ls2nud43	192	10	intrathecally	intrathecally	RB
cord-355413-ls2nud43	192	11	and	and	CC
cord-355413-ls2nud43	192	12	activate	activate	VB
cord-355413-ls2nud43	192	13	NK	NK	NNP
cord-355413-ls2nud43	192	14	cells	cell	NNS
cord-355413-ls2nud43	192	15	.	.	.
cord-355413-ls2nud43	193	1	Ewend	Ewend	NNP
cord-355413-ls2nud43	193	2	and	and	CC
cord-355413-ls2nud43	193	3	associates	associate	NNS
cord-355413-ls2nud43	193	4	carried	carry	VBD
cord-355413-ls2nud43	193	5	out	out	RP
cord-355413-ls2nud43	193	6	a	a	DT
cord-355413-ls2nud43	193	7	study	study	NN
cord-355413-ls2nud43	193	8	in	in	IN
cord-355413-ls2nud43	193	9	C57BL/6	C57BL/6	NNP
cord-355413-ls2nud43	193	10	mice	mouse	NNS
cord-355413-ls2nud43	193	11	that	that	WDT
cord-355413-ls2nud43	193	12	were	be	VBD
cord-355413-ls2nud43	193	13	simultaneously	simultaneously	RB
cord-355413-ls2nud43	193	14	given	give	VBN
cord-355413-ls2nud43	193	15	intracranial	intracranial	JJ
cord-355413-ls2nud43	193	16	injections	injection	NNS
cord-355413-ls2nud43	193	17	of	of	IN
cord-355413-ls2nud43	193	18	tumour	tumour	NN
cord-355413-ls2nud43	193	19	and	and	CC
cord-355413-ls2nud43	193	20	of	of	IN
cord-355413-ls2nud43	193	21	irradiated	irradiate	VBN
cord-355413-ls2nud43	193	22	B16F10	b16f10	JJ
cord-355413-ls2nud43	193	23	melanoma	melanoma	NN
cord-355413-ls2nud43	193	24	cells	cell	NNS
cord-355413-ls2nud43	193	25	transduced	transduce	VBN
cord-355413-ls2nud43	193	26	to	to	IN
cord-355413-ls2nud43	193	27	secrete	secrete	VB
cord-355413-ls2nud43	193	28	IL-2	il-2	NN
cord-355413-ls2nud43	193	29	(	(	-LRB-
cord-355413-ls2nud43	193	30	Prins	Prins	NNP
cord-355413-ls2nud43	193	31	et	et	NNP
cord-355413-ls2nud43	193	32	al	al	NNP
cord-355413-ls2nud43	193	33	.	.	NNP
cord-355413-ls2nud43	193	34	,	,	,
cord-355413-ls2nud43	193	35	2006	2006	CD
cord-355413-ls2nud43	193	36	)	)	-RRB-
cord-355413-ls2nud43	193	37	.	.	.
cord-355413-ls2nud43	194	1	IL-2	IL-2	NNP
cord-355413-ls2nud43	194	2	therapy	therapy	NN
cord-355413-ls2nud43	194	3	generated	generate	VBD
cord-355413-ls2nud43	194	4	antitumour	antitumour	NN
cord-355413-ls2nud43	194	5	responses	response	NNS
cord-355413-ls2nud43	194	6	capable	capable	JJ
cord-355413-ls2nud43	194	7	of	of	IN
cord-355413-ls2nud43	194	8	extending	extend	VBG
cord-355413-ls2nud43	194	9	the	the	DT
cord-355413-ls2nud43	194	10	survival	survival	NN
cord-355413-ls2nud43	194	11	of	of	IN
cord-355413-ls2nud43	194	12	animals	animal	NNS
cord-355413-ls2nud43	194	13	that	that	WDT
cord-355413-ls2nud43	194	14	received	receive	VBD
cord-355413-ls2nud43	194	15	simultaneous	simultaneous	JJ
cord-355413-ls2nud43	194	16	intracranial	intracranial	JJ
cord-355413-ls2nud43	194	17	tumour	tumour	NN
cord-355413-ls2nud43	194	18	challenges	challenge	NNS
cord-355413-ls2nud43	194	19	either	either	CC
cord-355413-ls2nud43	194	20	locally	locally	RB
cord-355413-ls2nud43	194	21	or	or	CC
cord-355413-ls2nud43	194	22	at	at	IN
cord-355413-ls2nud43	194	23	distant	distant	JJ
cord-355413-ls2nud43	194	24	sites	site	NNS
cord-355413-ls2nud43	194	25	in	in	IN
cord-355413-ls2nud43	194	26	the	the	DT
cord-355413-ls2nud43	194	27	brain	brain	NN
cord-355413-ls2nud43	194	28	.	.	.
cord-355413-ls2nud43	195	1	Non	non	JJ
cord-355413-ls2nud43	195	2	-	-	JJ
cord-355413-ls2nud43	195	3	transduced	transduced	JJ
cord-355413-ls2nud43	195	4	melanoma	melanoma	NN
cord-355413-ls2nud43	195	5	cells	cell	NNS
cord-355413-ls2nud43	195	6	had	have	VBD
cord-355413-ls2nud43	195	7	little	little	JJ
cord-355413-ls2nud43	195	8	effect	effect	NN
cord-355413-ls2nud43	195	9	.	.	.
cord-355413-ls2nud43	196	1	Elimination	elimination	NN
cord-355413-ls2nud43	196	2	of	of	IN
cord-355413-ls2nud43	196	3	T	t	NN
cord-355413-ls2nud43	196	4	-	-	HYPH
cord-355413-ls2nud43	196	5	cell	cell	NN
cord-355413-ls2nud43	196	6	and	and	CC
cord-355413-ls2nud43	196	7	NK	NK	NNP
cord-355413-ls2nud43	196	8	subsets	subset	NNS
cord-355413-ls2nud43	196	9	using	use	VBG
cord-355413-ls2nud43	196	10	gene	gene	NN
cord-355413-ls2nud43	196	11	KO	KO	NNP
cord-355413-ls2nud43	196	12	mice	mouse	NNS
cord-355413-ls2nud43	196	13	and	and	CC
cord-355413-ls2nud43	196	14	antibody	antibody	NN
cord-355413-ls2nud43	196	15	-	-	HYPH
cord-355413-ls2nud43	196	16	depletion	depletion	NN
cord-355413-ls2nud43	196	17	techniques	technique	NNS
cord-355413-ls2nud43	196	18	demonstrated	demonstrate	VBD
cord-355413-ls2nud43	196	19	that	that	IN
cord-355413-ls2nud43	196	20	NK	NK	NNP
cord-355413-ls2nud43	196	21	cells	cell	NNS
cord-355413-ls2nud43	196	22	were	be	VBD
cord-355413-ls2nud43	196	23	most	most	RBS
cord-355413-ls2nud43	196	24	important	important	JJ
cord-355413-ls2nud43	196	25	for	for	IN
cord-355413-ls2nud43	196	26	the	the	DT
cord-355413-ls2nud43	196	27	initial	initial	JJ
cord-355413-ls2nud43	196	28	anti	anti	JJ
cord-355413-ls2nud43	196	29	-	-	JJ
cord-355413-ls2nud43	196	30	tumour	tumour	JJ
cord-355413-ls2nud43	196	31	response	response	NN
cord-355413-ls2nud43	196	32	,	,	,
cord-355413-ls2nud43	196	33	whereas	whereas	IN
cord-355413-ls2nud43	196	34	CD4	CD4	NNP
cord-355413-ls2nud43	196	35			NNP
cord-355413-ls2nud43	196	36	T	T	NNP
cord-355413-ls2nud43	196	37	cells	cell	NNS
cord-355413-ls2nud43	196	38	were	be	VBD
cord-355413-ls2nud43	196	39	not	not	RB
cord-355413-ls2nud43	196	40	necessary	necessary	JJ
cord-355413-ls2nud43	196	41	.	.	.
cord-355413-ls2nud43	197	1	These	these	DT
cord-355413-ls2nud43	197	2	studies	study	NNS
cord-355413-ls2nud43	197	3	demonstrate	demonstrate	VBP
cord-355413-ls2nud43	197	4	that	that	IN
cord-355413-ls2nud43	197	5	local	local	JJ
cord-355413-ls2nud43	197	6	IL-2	IL-2	NNP
cord-355413-ls2nud43	197	7	therapy	therapy	NN
cord-355413-ls2nud43	197	8	in	in	IN
cord-355413-ls2nud43	197	9	the	the	DT
cord-355413-ls2nud43	197	10	brain	brain	NN
cord-355413-ls2nud43	197	11	not	not	RB
cord-355413-ls2nud43	197	12	only	only	RB
cord-355413-ls2nud43	197	13	generates	generate	VBZ
cord-355413-ls2nud43	197	14	an	an	DT
cord-355413-ls2nud43	197	15	immediate	immediate	JJ
cord-355413-ls2nud43	197	16	local	local	JJ
cord-355413-ls2nud43	197	17	antitumour	antitumour	JJ
cord-355413-ls2nud43	197	18	immune	immune	JJ
cord-355413-ls2nud43	197	19	response	response	NN
cord-355413-ls2nud43	197	20	,	,	,
cord-355413-ls2nud43	197	21	but	but	CC
cord-355413-ls2nud43	197	22	also	also	RB
cord-355413-ls2nud43	197	23	establishes	establish	VBZ
cord-355413-ls2nud43	197	24	long	long	JJ
cord-355413-ls2nud43	197	25	-	-	HYPH
cord-355413-ls2nud43	197	26	term	term	NN
cord-355413-ls2nud43	197	27	immunologic	immunologic	JJ
cord-355413-ls2nud43	197	28	memory	memory	NN
cord-355413-ls2nud43	197	29	capable	capable	JJ
cord-355413-ls2nud43	197	30	of	of	IN
cord-355413-ls2nud43	197	31	eliminating	eliminate	VBG
cord-355413-ls2nud43	197	32	subsequent	subsequent	JJ
cord-355413-ls2nud43	197	33	tumour	tumour	NN
cord-355413-ls2nud43	197	34	challenges	challenge	NNS
cord-355413-ls2nud43	197	35	within	within	IN
cord-355413-ls2nud43	197	36	and	and	CC
cord-355413-ls2nud43	197	37	outside	outside	RB
cord-355413-ls2nud43	197	38	of	of	IN
cord-355413-ls2nud43	197	39	the	the	DT
cord-355413-ls2nud43	197	40	CNS	CNS	NNP
cord-355413-ls2nud43	197	41	.	.	.
cord-355413-ls2nud43	198	1	Furthermore	furthermore	RB
cord-355413-ls2nud43	198	2	,	,	,
cord-355413-ls2nud43	198	3	the	the	DT
cord-355413-ls2nud43	198	4	antitumour	antitumour	JJ
cord-355413-ls2nud43	198	5	response	response	NN
cord-355413-ls2nud43	198	6	to	to	IN
cord-355413-ls2nud43	198	7	paracrine	paracrine	JJ
cord-355413-ls2nud43	198	8	IL-2	il-2	NN
cord-355413-ls2nud43	198	9	in	in	IN
cord-355413-ls2nud43	198	10	the	the	DT
cord-355413-ls2nud43	198	11	brain	brain	NN
cord-355413-ls2nud43	198	12	differed	differ	VBD
cord-355413-ls2nud43	198	13	significantly	significantly	RB
cord-355413-ls2nud43	198	14	from	from	IN
cord-355413-ls2nud43	198	15	that	that	DT
cord-355413-ls2nud43	198	16	in	in	IN
cord-355413-ls2nud43	198	17	the	the	DT
cord-355413-ls2nud43	198	18	flank	flank	NN
cord-355413-ls2nud43	198	19	,	,	,
cord-355413-ls2nud43	198	20	suggesting	suggest	VBG
cord-355413-ls2nud43	198	21	that	that	IN
cord-355413-ls2nud43	198	22	the	the	DT
cord-355413-ls2nud43	198	23	intrinsic	intrinsic	JJ
cord-355413-ls2nud43	198	24	CNS	CNS	NNP
cord-355413-ls2nud43	198	25	cells	cell	NNS
cord-355413-ls2nud43	198	26	involved	involve	VBN
cord-355413-ls2nud43	198	27	in	in	IN
cord-355413-ls2nud43	198	28	initiating	initiate	VBG
cord-355413-ls2nud43	198	29	immunity	immunity	NN
cord-355413-ls2nud43	198	30	within	within	IN
cord-355413-ls2nud43	198	31	the	the	DT
cord-355413-ls2nud43	198	32	brain	brain	NN
cord-355413-ls2nud43	198	33	have	have	VBP
cord-355413-ls2nud43	198	34	different	different	JJ
cord-355413-ls2nud43	198	35	cytokine	cytokine	NN
cord-355413-ls2nud43	198	36	requirements	requirement	NNS
cord-355413-ls2nud43	198	37	from	from	IN
cord-355413-ls2nud43	198	38	their	-PRON-	PRP$
cord-355413-ls2nud43	198	39	peripheral	peripheral	JJ
cord-355413-ls2nud43	198	40	counterparts	counterpart	NNS
cord-355413-ls2nud43	198	41	.	.	.
cord-355413-ls2nud43	199	1	Using	use	VBG
cord-355413-ls2nud43	199	2	the	the	DT
cord-355413-ls2nud43	199	3	same	same	JJ
cord-355413-ls2nud43	199	4	model	model	NN
cord-355413-ls2nud43	199	5	,	,	,
cord-355413-ls2nud43	199	6	a	a	DT
cord-355413-ls2nud43	199	7	recent	recent	JJ
cord-355413-ls2nud43	199	8	study	study	NN
cord-355413-ls2nud43	199	9	showed	show	VBD
cord-355413-ls2nud43	199	10	that	that	IN
cord-355413-ls2nud43	199	11	DCs	DCs	NNP
cord-355413-ls2nud43	199	12	administration	administration	NN
cord-355413-ls2nud43	199	13	induced	induce	VBD
cord-355413-ls2nud43	199	14	dramatic	dramatic	JJ
cord-355413-ls2nud43	199	15	anti	anti	JJ
cord-355413-ls2nud43	199	16	-	-	JJ
cord-355413-ls2nud43	199	17	tumour	tumour	JJ
cord-355413-ls2nud43	199	18	immune	immune	JJ
cord-355413-ls2nud43	199	19	protection	protection	NN
cord-355413-ls2nud43	199	20	in	in	IN
cord-355413-ls2nud43	199	21	CD8	CD8	NNP
cord-355413-ls2nud43	199	22	KO	KO	NNP
cord-355413-ls2nud43	199	23	mice	mouse	NNS
cord-355413-ls2nud43	199	24	that	that	WDT
cord-355413-ls2nud43	199	25	were	be	VBD
cord-355413-ls2nud43	199	26	challenged	challenge	VBN
cord-355413-ls2nud43	199	27	with	with	IN
cord-355413-ls2nud43	199	28	B16	B16	NNP
cord-355413-ls2nud43	199	29	melanoma	melanoma	NN
cord-355413-ls2nud43	199	30	both	both	CC
cord-355413-ls2nud43	199	31	subcutaneously	subcutaneously	RB
cord-355413-ls2nud43	199	32	and	and	CC
cord-355413-ls2nud43	199	33	in	in	IN
cord-355413-ls2nud43	199	34	the	the	DT
cord-355413-ls2nud43	199	35	brain	brain	NN
cord-355413-ls2nud43	200	1	(	(	-LRB-
cord-355413-ls2nud43	200	2	Ewend	Ewend	NNP
cord-355413-ls2nud43	200	3	et	et	NNP
cord-355413-ls2nud43	200	4	al	al	NNP
cord-355413-ls2nud43	200	5	.	.	NNP
cord-355413-ls2nud43	200	6	,	,	,
cord-355413-ls2nud43	200	7	2000	2000	CD
cord-355413-ls2nud43	200	8	)	)	-RRB-
cord-355413-ls2nud43	200	9	.	.	.
cord-355413-ls2nud43	201	1	The	the	DT
cord-355413-ls2nud43	201	2	CNS	CNS	NNP
cord-355413-ls2nud43	201	3	anti	anti	JJ
cord-355413-ls2nud43	201	4	-	-	JJ
cord-355413-ls2nud43	201	5	tumour	tumour	JJ
cord-355413-ls2nud43	201	6	immunity	immunity	NN
cord-355413-ls2nud43	201	7	was	be	VBD
cord-355413-ls2nud43	201	8	dependant	dependant	JJ
cord-355413-ls2nud43	201	9	on	on	IN
cord-355413-ls2nud43	201	10	both	both	DT
cord-355413-ls2nud43	201	11	CD4	CD4	NNP
cord-355413-ls2nud43	201	12			NNP
cord-355413-ls2nud43	201	13	T	T	NNP
cord-355413-ls2nud43	201	14	cells	cell	NNS
cord-355413-ls2nud43	201	15	and	and	CC
cord-355413-ls2nud43	201	16	NK	NK	NNP
cord-355413-ls2nud43	201	17	cells	cell	NNS
cord-355413-ls2nud43	201	18	.	.	.
cord-355413-ls2nud43	202	1	Administration	Administration	NNP
cord-355413-ls2nud43	202	2	of	of	IN
cord-355413-ls2nud43	202	3	non	non	JJ
cord-355413-ls2nud43	202	4	-	-	JJ
cord-355413-ls2nud43	202	5	Ag	Ag	NNP
cord-355413-ls2nud43	202	6	-	-	HYPH
cord-355413-ls2nud43	202	7	loaded	load	VBN
cord-355413-ls2nud43	202	8	,	,	,
cord-355413-ls2nud43	202	9	immature	immature	JJ
cord-355413-ls2nud43	202	10	DC	DC	NNP
cord-355413-ls2nud43	202	11	resulted	result	VBD
cord-355413-ls2nud43	202	12	in	in	IN
cord-355413-ls2nud43	202	13	significant	significant	JJ
cord-355413-ls2nud43	202	14	CD4	CD4	NNP
cord-355413-ls2nud43	202	15			NNP
cord-355413-ls2nud43	202	16	T	T	NNP
cord-355413-ls2nud43	202	17	cell	cell	NN
cord-355413-ls2nud43	202	18	and	and	CC
cord-355413-ls2nud43	202	19	NK	NK	NNP
cord-355413-ls2nud43	202	20	cell	cell	NN
cord-355413-ls2nud43	202	21	expansion	expansion	NN
cord-355413-ls2nud43	202	22	in	in	IN
cord-355413-ls2nud43	202	23	the	the	DT
cord-355413-ls2nud43	202	24	draining	drain	VBG
cord-355413-ls2nud43	202	25	lymph	lymph	NN
cord-355413-ls2nud43	202	26	nodes	node	NNS
cord-355413-ls2nud43	202	27	at	at	IN
cord-355413-ls2nud43	202	28	6	6	CD
cord-355413-ls2nud43	202	29	days	day	NNS
cord-355413-ls2nud43	202	30	post	post	NN
cord-355413-ls2nud43	202	31	-	-	NN
cord-355413-ls2nud43	202	32	vaccination	vaccination	NN
cord-355413-ls2nud43	202	33	,	,	,
cord-355413-ls2nud43	202	34	which	which	WDT
cord-355413-ls2nud43	202	35	persisted	persist	VBD
cord-355413-ls2nud43	202	36	for	for	IN
cord-355413-ls2nud43	202	37	2	2	CD
cord-355413-ls2nud43	202	38	weeks	week	NNS
cord-355413-ls2nud43	202	39	.	.	.
cord-355413-ls2nud43	203	1	Finally	finally	RB
cord-355413-ls2nud43	203	2	,	,	,
cord-355413-ls2nud43	203	3	Ag	Ag	NNP
cord-355413-ls2nud43	203	4	-	-	HYPH
cord-355413-ls2nud43	203	5	loaded	load	VBN
cord-355413-ls2nud43	203	6	DC	DC	NNP
cord-355413-ls2nud43	203	7	administration	administration	NN
cord-355413-ls2nud43	203	8	in	in	IN
cord-355413-ls2nud43	203	9	CD8	CD8	NNP
cord-355413-ls2nud43	203	10	KO	KO	NNP
cord-355413-ls2nud43	203	11	mice	mouse	NNS
cord-355413-ls2nud43	203	12	was	be	VBD
cord-355413-ls2nud43	203	13	associated	associate	VBN
cord-355413-ls2nud43	203	14	with	with	IN
cord-355413-ls2nud43	203	15	robust	robust	JJ
cord-355413-ls2nud43	203	16	infiltration	infiltration	NN
cord-355413-ls2nud43	203	17	of	of	IN
cord-355413-ls2nud43	203	18	CD4	CD4	NNP
cord-355413-ls2nud43	203	19			NNP
cord-355413-ls2nud43	203	20	T	T	NNP
cord-355413-ls2nud43	203	21	cells	cell	NNS
cord-355413-ls2nud43	203	22	and	and	CC
cord-355413-ls2nud43	203	23	NK	NK	NNP
cord-355413-ls2nud43	203	24	cells	cell	NNS
cord-355413-ls2nud43	203	25	into	into	IN
cord-355413-ls2nud43	203	26	the	the	DT
cord-355413-ls2nud43	203	27	brain	brain	NN
cord-355413-ls2nud43	203	28	tumour	tumour	NN
cord-355413-ls2nud43	203	29	parenchyma	parenchyma	NN
cord-355413-ls2nud43	203	30	(	(	-LRB-
cord-355413-ls2nud43	203	31	Ewend	Ewend	NNP
cord-355413-ls2nud43	203	32	et	et	NNP
cord-355413-ls2nud43	203	33	al	al	NNP
cord-355413-ls2nud43	203	34	.	.	NNP
cord-355413-ls2nud43	203	35	,	,	,
cord-355413-ls2nud43	203	36	2000	2000	CD
cord-355413-ls2nud43	203	37	)	)	-RRB-
cord-355413-ls2nud43	203	38	.	.	.
cord-355413-ls2nud43	204	1	Glioma	Glioma	NNP
cord-355413-ls2nud43	204	2	cells	cell	NNS
cord-355413-ls2nud43	204	3	interfere	interfere	VBP
cord-355413-ls2nud43	204	4	with	with	IN
cord-355413-ls2nud43	204	5	anti	anti	JJ
cord-355413-ls2nud43	204	6	-	-	JJ
cord-355413-ls2nud43	204	7	tumour	tumour	JJ
cord-355413-ls2nud43	204	8	immune	immune	JJ
cord-355413-ls2nud43	204	9	responses	response	NNS
cord-355413-ls2nud43	204	10	by	by	IN
cord-355413-ls2nud43	204	11	expressing	express	VBG
cord-355413-ls2nud43	204	12	immune	immune	JJ
cord-355413-ls2nud43	204	13	inhibitory	inhibitory	JJ
cord-355413-ls2nud43	204	14	cell	cell	NN
cord-355413-ls2nud43	204	15	surface	surface	NN
cord-355413-ls2nud43	204	16	molecules	molecule	NNS
cord-355413-ls2nud43	204	17	,	,	,
cord-355413-ls2nud43	204	18	such	such	JJ
cord-355413-ls2nud43	204	19	as	as	IN
cord-355413-ls2nud43	204	20	HLA	HLA	NNP
cord-355413-ls2nud43	204	21	-	-	HYPH
cord-355413-ls2nud43	204	22	G	G	NNP
cord-355413-ls2nud43	204	23	,	,	,
cord-355413-ls2nud43	204	24	or	or	CC
cord-355413-ls2nud43	204	25	by	by	IN
cord-355413-ls2nud43	204	26	releasing	release	VBG
cord-355413-ls2nud43	204	27	soluble	soluble	JJ
cord-355413-ls2nud43	204	28	immunosuppressants	immunosuppressant	NNS
cord-355413-ls2nud43	204	29	such	such	JJ
cord-355413-ls2nud43	204	30	as	as	IN
cord-355413-ls2nud43	204	31	transforming	transform	VBG
cord-355413-ls2nud43	204	32	growth	growth	NN
cord-355413-ls2nud43	204	33	factor	factor	NN
cord-355413-ls2nud43	204	34	(	(	-LRB-
cord-355413-ls2nud43	204	35	TGF-	TGF-	NNP
cord-355413-ls2nud43	204	36	)	)	-RRB-
cord-355413-ls2nud43	204	37	.	.	.
cord-355413-ls2nud43	205	1	They	-PRON-	PRP
cord-355413-ls2nud43	205	2	rarely	rarely	RB
cord-355413-ls2nud43	205	3	metastasize	metastasize	VBP
cord-355413-ls2nud43	205	4	outside	outside	IN
cord-355413-ls2nud43	205	5	the	the	DT
cord-355413-ls2nud43	205	6	brain	brain	NN
cord-355413-ls2nud43	205	7	,	,	,
cord-355413-ls2nud43	205	8	raising	raise	VBG
cord-355413-ls2nud43	205	9	the	the	DT
cord-355413-ls2nud43	205	10	possibility	possibility	NN
cord-355413-ls2nud43	205	11	of	of	IN
cord-355413-ls2nud43	205	12	immune	immune	NN
cord-355413-ls2nud43	205	13	-	-	HYPH
cord-355413-ls2nud43	205	14	mediated	mediate	VBN
cord-355413-ls2nud43	205	15	control	control	NN
cord-355413-ls2nud43	205	16	of	of	IN
cord-355413-ls2nud43	205	17	these	these	DT
cord-355413-ls2nud43	205	18	cells	cell	NNS
cord-355413-ls2nud43	205	19	outside	outside	RB
cord-355413-ls2nud43	205	20	,	,	,
cord-355413-ls2nud43	205	21	but	but	CC
cord-355413-ls2nud43	205	22	not	not	RB
cord-355413-ls2nud43	205	23	inside	inside	RB
cord-355413-ls2nud43	205	24	,	,	,
cord-355413-ls2nud43	205	25	the	the	DT
cord-355413-ls2nud43	205	26	brain	brain	NN
cord-355413-ls2nud43	205	27	.	.	.
cord-355413-ls2nud43	206	1	IL-2	IL-2	NNP
cord-355413-ls2nud43	206	2	,	,	,
cord-355413-ls2nud43	206	3	as	as	RB
cord-355413-ls2nud43	206	4	well	well	RB
cord-355413-ls2nud43	206	5	as	as	IN
cord-355413-ls2nud43	206	6	growth	growth	NN
cord-355413-ls2nud43	206	7	hormone	hormone	NN
cord-355413-ls2nud43	206	8	,	,	,
cord-355413-ls2nud43	206	9	is	be	VBZ
cord-355413-ls2nud43	206	10	potent	potent	JJ
cord-355413-ls2nud43	206	11	in	in	IN
cord-355413-ls2nud43	206	12	enhancing	enhance	VBG
cord-355413-ls2nud43	206	13	NK	NK	NNP
cord-355413-ls2nud43	206	14	cell	cell	NN
cord-355413-ls2nud43	206	15	activity	activity	NN
cord-355413-ls2nud43	206	16	against	against	IN
cord-355413-ls2nud43	206	17	glioma	glioma	NN
cord-355413-ls2nud43	206	18	both	both	CC
cord-355413-ls2nud43	206	19	in	in	IN
cord-355413-ls2nud43	206	20	human	human	JJ
cord-355413-ls2nud43	206	21	trials	trial	NNS
cord-355413-ls2nud43	206	22	and	and	CC
cord-355413-ls2nud43	206	23	in	in	IN
cord-355413-ls2nud43	206	24	several	several	JJ
cord-355413-ls2nud43	206	25	experimental	experimental	JJ
cord-355413-ls2nud43	206	26	systems	system	NNS
cord-355413-ls2nud43	207	1	(	(	-LRB-
cord-355413-ls2nud43	207	2	Eisele	Eisele	NNP
cord-355413-ls2nud43	207	3	et	et	FW
cord-355413-ls2nud43	207	4	al	al	NNP
cord-355413-ls2nud43	207	5	.	.	NNP
cord-355413-ls2nud43	207	6	,	,	,
cord-355413-ls2nud43	207	7	2006	2006	CD
cord-355413-ls2nud43	207	8	;	;	.
cord-355413-ls2nud43	208	1	Hayes	Hayes	NNP
cord-355413-ls2nud43	208	2	et	et	NNP
cord-355413-ls2nud43	208	3	al	al	NNP
cord-355413-ls2nud43	208	4	.	.	.
cord-355413-ls2nud43	209	1	,	,	,
cord-355413-ls2nud43	209	2	1995	1995	CD
cord-355413-ls2nud43	209	3	;	;	:
cord-355413-ls2nud43	209	4	Shimizu	Shimizu	NNP
cord-355413-ls2nud43	209	5	et	et	NNP
cord-355413-ls2nud43	209	6	al	al	NNP
cord-355413-ls2nud43	209	7	.	.	.
cord-355413-ls2nud43	210	1	,	,	,
cord-355413-ls2nud43	210	2	2005	2005	CD
cord-355413-ls2nud43	210	3	;	;	:
cord-355413-ls2nud43	210	4	Wischhusen	Wischhusen	NNP
cord-355413-ls2nud43	210	5	et	et	FW
cord-355413-ls2nud43	210	6	al	al	NNP
cord-355413-ls2nud43	210	7	.	.	NNP
cord-355413-ls2nud43	210	8	,	,	,
cord-355413-ls2nud43	210	9	2005	2005	CD
cord-355413-ls2nud43	210	10	)	)	-RRB-
cord-355413-ls2nud43	210	11	.	.	.
cord-355413-ls2nud43	211	1	As	as	IN
cord-355413-ls2nud43	211	2	receptors	receptor	NNS
cord-355413-ls2nud43	211	3	governing	govern	VBG
cord-355413-ls2nud43	211	4	NK	NK	NNP
cord-355413-ls2nud43	211	5	cell	cell	NN
cord-355413-ls2nud43	211	6	action	action	NN
cord-355413-ls2nud43	211	7	and	and	CC
cord-355413-ls2nud43	211	8	effector	effector	NN
cord-355413-ls2nud43	211	9	functions	function	NNS
cord-355413-ls2nud43	211	10	are	be	VBP
cord-355413-ls2nud43	211	11	being	be	VBG
cord-355413-ls2nud43	211	12	elucidated	elucidate	VBN
cord-355413-ls2nud43	211	13	,	,	,
cord-355413-ls2nud43	211	14	more	more	RBR
cord-355413-ls2nud43	211	15	sophisticated	sophisticated	JJ
cord-355413-ls2nud43	211	16	means	mean	NNS
cord-355413-ls2nud43	211	17	of	of	IN
cord-355413-ls2nud43	211	18	manipulating	manipulate	VBG
cord-355413-ls2nud43	211	19	NK	NK	NNP
cord-355413-ls2nud43	211	20	cells	cell	NNS
cord-355413-ls2nud43	211	21	have	have	VBP
cord-355413-ls2nud43	211	22	been	be	VBN
cord-355413-ls2nud43	211	23	generated	generate	VBN
cord-355413-ls2nud43	211	24	.	.	.
cord-355413-ls2nud43	212	1	As	as	IN
cord-355413-ls2nud43	212	2	noted	note	VBN
cord-355413-ls2nud43	212	3	above	above	RB
cord-355413-ls2nud43	212	4	,	,	,
cord-355413-ls2nud43	212	5	NKG2D	nkg2d	NN
cord-355413-ls2nud43	212	6	is	be	VBZ
cord-355413-ls2nud43	212	7	a	a	DT
cord-355413-ls2nud43	212	8	powerful	powerful	JJ
cord-355413-ls2nud43	212	9	,	,	,
cord-355413-ls2nud43	212	10	activating	activate	VBG
cord-355413-ls2nud43	212	11	NK	NK	NNP
cord-355413-ls2nud43	212	12	cell	cell	NN
cord-355413-ls2nud43	212	13	receptor	receptor	NN
cord-355413-ls2nud43	212	14	(	(	-LRB-
cord-355413-ls2nud43	212	15	Wischhusen	Wischhusen	NNP
cord-355413-ls2nud43	212	16	et	et	FW
cord-355413-ls2nud43	212	17	al	al	NNP
cord-355413-ls2nud43	212	18	.	.	NNP
cord-355413-ls2nud43	212	19	,	,	,
cord-355413-ls2nud43	212	20	2005	2005	CD
cord-355413-ls2nud43	212	21	)	)	-RRB-
cord-355413-ls2nud43	212	22	.	.	.
cord-355413-ls2nud43	213	1	Accordingly	accordingly	RB
cord-355413-ls2nud43	213	2	,	,	,
cord-355413-ls2nud43	213	3	activating	activate	VBG
cord-355413-ls2nud43	213	4	the	the	DT
cord-355413-ls2nud43	213	5	innate	innate	JJ
cord-355413-ls2nud43	213	6	immune	immune	JJ
cord-355413-ls2nud43	213	7	system	system	NN
cord-355413-ls2nud43	213	8	by	by	IN
cord-355413-ls2nud43	213	9	forcing	force	VBG
cord-355413-ls2nud43	213	10	glioma	glioma	NN
cord-355413-ls2nud43	213	11	cells	cell	NNS
cord-355413-ls2nud43	213	12	to	to	TO
cord-355413-ls2nud43	213	13	express	express	VB
cord-355413-ls2nud43	213	14	danger	danger	NN
cord-355413-ls2nud43	213	15	signals	signal	NNS
cord-355413-ls2nud43	213	16	such	such	JJ
cord-355413-ls2nud43	213	17	as	as	IN
cord-355413-ls2nud43	213	18	NKG2D	nkg2d	NN
cord-355413-ls2nud43	213	19	ligands	ligand	NNS
cord-355413-ls2nud43	213	20	is	be	VBZ
cord-355413-ls2nud43	213	21	a	a	DT
cord-355413-ls2nud43	213	22	promising	promising	JJ
cord-355413-ls2nud43	213	23	strategy	strategy	NN
cord-355413-ls2nud43	213	24	of	of	IN
cord-355413-ls2nud43	213	25	immunotherapy	immunotherapy	NN
cord-355413-ls2nud43	213	26	for	for	IN
cord-355413-ls2nud43	213	27	these	these	DT
cord-355413-ls2nud43	213	28	tumours	tumour	NNS
cord-355413-ls2nud43	213	29	.	.	.
cord-355413-ls2nud43	214	1	The	the	DT
cord-355413-ls2nud43	214	2	remaining	remain	VBG
cord-355413-ls2nud43	214	3	challenges	challenge	NNS
cord-355413-ls2nud43	214	4	would	would	MD
cord-355413-ls2nud43	214	5	be	be	VB
cord-355413-ls2nud43	214	6	to	to	TO
cord-355413-ls2nud43	214	7	downregulate	downregulate	VB
cord-355413-ls2nud43	214	8	HLA	HLA	NNP
cord-355413-ls2nud43	214	9	-	-	HYPH
cord-355413-ls2nud43	214	10	E	e	NN
cord-355413-ls2nud43	214	11	expression	expression	NN
cord-355413-ls2nud43	214	12	on	on	IN
cord-355413-ls2nud43	214	13	glioma	glioma	NN
cord-355413-ls2nud43	214	14	cells	cell	NNS
cord-355413-ls2nud43	214	15	and	and	CC
cord-355413-ls2nud43	214	16	suppress	suppress	VB
cord-355413-ls2nud43	214	17	production	production	NN
cord-355413-ls2nud43	214	18	of	of	IN
cord-355413-ls2nud43	214	19	TGF-	TGF-	NNP
cord-355413-ls2nud43	214	20	by	by	IN
cord-355413-ls2nud43	214	21	glioma	glioma	NN
cord-355413-ls2nud43	214	22	.	.	.
cord-355413-ls2nud43	215	1	Both	both	DT
cord-355413-ls2nud43	215	2	HLA	HLA	NNP
cord-355413-ls2nud43	215	3	-	-	HYPH
cord-355413-ls2nud43	215	4	E	E	NNP
cord-355413-ls2nud43	215	5	and	and	CC
cord-355413-ls2nud43	215	6	TGFbeta	TGFbeta	NNP
cord-355413-ls2nud43	215	7	can	can	MD
cord-355413-ls2nud43	215	8	down	down	RB
cord-355413-ls2nud43	215	9	-	-	HYPH
cord-355413-ls2nud43	215	10	regulate	regulate	VB
cord-355413-ls2nud43	215	11	NKG2D	nkg2d	JJ
cord-355413-ls2nud43	215	12	expression	expression	NN
cord-355413-ls2nud43	215	13	on	on	IN
cord-355413-ls2nud43	215	14	glioma	glioma	NN
cord-355413-ls2nud43	215	15	,	,	,
cord-355413-ls2nud43	215	16	which	which	WDT
cord-355413-ls2nud43	215	17	enable	enable	VBP
cord-355413-ls2nud43	215	18	these	these	DT
cord-355413-ls2nud43	215	19	tumour	tumour	NN
cord-355413-ls2nud43	215	20	cells	cell	NNS
cord-355413-ls2nud43	215	21	to	to	TO
cord-355413-ls2nud43	215	22	escape	escape	VB
cord-355413-ls2nud43	215	23	NK	NK	NNP
cord-355413-ls2nud43	215	24	cell	cell	NN
cord-355413-ls2nud43	215	25	surveillance	surveillance	NN
cord-355413-ls2nud43	215	26	.	.	.
cord-355413-ls2nud43	216	1	Various	various	JJ
cord-355413-ls2nud43	216	2	studies	study	NNS
cord-355413-ls2nud43	216	3	have	have	VBP
cord-355413-ls2nud43	216	4	documented	document	VBN
cord-355413-ls2nud43	216	5	the	the	DT
cord-355413-ls2nud43	216	6	role	role	NN
cord-355413-ls2nud43	216	7	of	of	IN
cord-355413-ls2nud43	216	8	NK	NK	NNP
cord-355413-ls2nud43	216	9	cells	cell	NNS
cord-355413-ls2nud43	216	10	in	in	IN
cord-355413-ls2nud43	216	11	surveillance	surveillance	NN
cord-355413-ls2nud43	216	12	and	and	CC
cord-355413-ls2nud43	216	13	suppression	suppression	NN
cord-355413-ls2nud43	216	14	of	of	IN
cord-355413-ls2nud43	216	15	other	other	JJ
cord-355413-ls2nud43	216	16	type	type	NN
cord-355413-ls2nud43	216	17	of	of	IN
cord-355413-ls2nud43	216	18	CNS	CNS	NNP
cord-355413-ls2nud43	216	19	tumours	tumour	NNS
cord-355413-ls2nud43	216	20	including	include	VBG
cord-355413-ls2nud43	216	21	medulloblastoma	medulloblastoma	NNP
cord-355413-ls2nud43	216	22	(	(	-LRB-
cord-355413-ls2nud43	216	23	Castriconi	Castriconi	NNP
cord-355413-ls2nud43	216	24	et	et	NNP
cord-355413-ls2nud43	216	25	al	al	NNP
cord-355413-ls2nud43	216	26	.	.	NNP
cord-355413-ls2nud43	216	27	,	,	,
cord-355413-ls2nud43	216	28	2007	2007	CD
cord-355413-ls2nud43	216	29	)	)	-RRB-
cord-355413-ls2nud43	216	30	,	,	,
cord-355413-ls2nud43	216	31	astrocytoma	astrocytoma	NN
cord-355413-ls2nud43	216	32	and	and	CC
cord-355413-ls2nud43	216	33	neuroblastoma	neuroblastoma	NN
cord-355413-ls2nud43	216	34	(	(	-LRB-
cord-355413-ls2nud43	216	35	Kang	Kang	NNP
cord-355413-ls2nud43	216	36	et	et	NNP
cord-355413-ls2nud43	216	37	al	al	NNP
cord-355413-ls2nud43	216	38	.	.	NNP
cord-355413-ls2nud43	216	39	,	,	,
cord-355413-ls2nud43	216	40	2004	2004	CD
cord-355413-ls2nud43	216	41	)	)	-RRB-
cord-355413-ls2nud43	216	42	.	.	.
cord-355413-ls2nud43	217	1	On	on	IN
cord-355413-ls2nud43	217	2	the	the	DT
cord-355413-ls2nud43	217	3	other	other	JJ
cord-355413-ls2nud43	217	4	hand	hand	NN
cord-355413-ls2nud43	217	5	NK	NK	NNP
cord-355413-ls2nud43	217	6	cells	cell	NNS
cord-355413-ls2nud43	217	7	appear	appear	VBP
cord-355413-ls2nud43	217	8	to	to	TO
cord-355413-ls2nud43	217	9	have	have	VB
cord-355413-ls2nud43	217	10	little	little	JJ
cord-355413-ls2nud43	217	11	,	,	,
cord-355413-ls2nud43	217	12	if	if	IN
cord-355413-ls2nud43	217	13	any	any	DT
cord-355413-ls2nud43	217	14	,	,	,
cord-355413-ls2nud43	217	15	role	role	NN
cord-355413-ls2nud43	217	16	in	in	IN
cord-355413-ls2nud43	217	17	suppressing	suppress	VBG
cord-355413-ls2nud43	217	18	CNS	CNS	NNP
cord-355413-ls2nud43	217	19	lymphomas	lymphoma	NNS
cord-355413-ls2nud43	217	20	(	(	-LRB-
cord-355413-ls2nud43	217	21	Yamasaki	Yamasaki	NNP
cord-355413-ls2nud43	217	22	et	et	NNP
cord-355413-ls2nud43	217	23	al	al	NNP
cord-355413-ls2nud43	217	24	.	.	NNP
cord-355413-ls2nud43	217	25	,	,	,
cord-355413-ls2nud43	217	26	2003	2003	CD
cord-355413-ls2nud43	217	27	)	)	-RRB-
cord-355413-ls2nud43	217	28	.	.	.
cord-355413-ls2nud43	218	1	Clearly	clearly	RB
cord-355413-ls2nud43	218	2	,	,	,
cord-355413-ls2nud43	218	3	cumulative	cumulative	JJ
cord-355413-ls2nud43	218	4	evidence	evidence	NN
cord-355413-ls2nud43	218	5	suggests	suggest	VBZ
cord-355413-ls2nud43	218	6	that	that	IN
cord-355413-ls2nud43	218	7	NK	NK	NNP
cord-355413-ls2nud43	218	8	cells	cell	NNS
cord-355413-ls2nud43	218	9	play	play	VBP
cord-355413-ls2nud43	218	10	a	a	DT
cord-355413-ls2nud43	218	11	role	role	NN
cord-355413-ls2nud43	218	12	in	in	IN
cord-355413-ls2nud43	218	13	curbing	curb	VBG
cord-355413-ls2nud43	218	14	malignant	malignant	JJ
cord-355413-ls2nud43	218	15	transformation	transformation	NN
cord-355413-ls2nud43	218	16	and	and	CC
cord-355413-ls2nud43	218	17	progression	progression	NN
cord-355413-ls2nud43	218	18	of	of	IN
cord-355413-ls2nud43	218	19	many	many	JJ
cord-355413-ls2nud43	218	20	primary	primary	JJ
cord-355413-ls2nud43	218	21	and	and	CC
cord-355413-ls2nud43	218	22	metastatic	metastatic	JJ
cord-355413-ls2nud43	218	23	CNS	CNS	NNP
cord-355413-ls2nud43	218	24	tumours	tumour	NNS
cord-355413-ls2nud43	218	25	(	(	-LRB-
cord-355413-ls2nud43	218	26	Table	Table	NNP
cord-355413-ls2nud43	218	27	28	28	CD
cord-355413-ls2nud43	218	28	.2	.2	CD
cord-355413-ls2nud43	218	29	)	)	-RRB-
cord-355413-ls2nud43	218	30	.	.	.
cord-355413-ls2nud43	219	1	Direct	direct	JJ
cord-355413-ls2nud43	219	2	cytotoxic	cytotoxic	JJ
cord-355413-ls2nud43	219	3	effects	effect	NNS
cord-355413-ls2nud43	219	4	and	and	CC
cord-355413-ls2nud43	219	5	collaboration	collaboration	NN
cord-355413-ls2nud43	219	6	with	with	IN
cord-355413-ls2nud43	219	7	T	T	NNP
cord-355413-ls2nud43	219	8	cells	cell	NNS
cord-355413-ls2nud43	219	9	and	and	CC
cord-355413-ls2nud43	219	10	other	other	JJ
cord-355413-ls2nud43	219	11	immune	immune	JJ
cord-355413-ls2nud43	219	12	cells	cell	NNS
cord-355413-ls2nud43	219	13	are	be	VBP
cord-355413-ls2nud43	219	14	required	require	VBN
cord-355413-ls2nud43	219	15	to	to	TO
cord-355413-ls2nud43	219	16	achieve	achieve	VB
cord-355413-ls2nud43	219	17	these	these	DT
cord-355413-ls2nud43	219	18	functions	function	NNS
cord-355413-ls2nud43	219	19	(	(	-LRB-
cord-355413-ls2nud43	219	20	Table	Table	NNP
cord-355413-ls2nud43	219	21	28	28	CD
cord-355413-ls2nud43	219	22	.2	.2	CD
cord-355413-ls2nud43	219	23	)	)	-RRB-
cord-355413-ls2nud43	219	24	.	.	.
cord-355413-ls2nud43	220	1	Effective	effective	JJ
cord-355413-ls2nud43	220	2	therapies	therapy	NNS
cord-355413-ls2nud43	220	3	harnessing	harness	VBG
cord-355413-ls2nud43	220	4	NK	NK	NNP
cord-355413-ls2nud43	220	5	cells	cell	NNS
cord-355413-ls2nud43	220	6	will	will	MD
cord-355413-ls2nud43	220	7	be	be	VB
cord-355413-ls2nud43	220	8	facilitated	facilitate	VBN
cord-355413-ls2nud43	220	9	through	through	IN
cord-355413-ls2nud43	220	10	understanding	understanding	NN
cord-355413-ls2nud43	220	11	of	of	IN
cord-355413-ls2nud43	220	12	the	the	DT
cord-355413-ls2nud43	220	13	molecular	molecular	JJ
cord-355413-ls2nud43	220	14	signalling	signal	VBG
cord-355413-ls2nud43	220	15	pathways	pathway	NNS
cord-355413-ls2nud43	220	16	that	that	WDT
cord-355413-ls2nud43	220	17	will	will	MD
cord-355413-ls2nud43	220	18	be	be	VB
cord-355413-ls2nud43	220	19	governing	govern	VBG
cord-355413-ls2nud43	220	20	NK	NK	NNP
cord-355413-ls2nud43	220	21	cell	cell	NN
cord-355413-ls2nud43	220	22	activation	activation	NN
cord-355413-ls2nud43	220	23	,	,	,
cord-355413-ls2nud43	220	24	expansion	expansion	NN
cord-355413-ls2nud43	220	25	and	and	CC
cord-355413-ls2nud43	220	26	maintenance	maintenance	NN
cord-355413-ls2nud43	220	27	.	.	.
cord-355413-ls2nud43	221	1	Specific	specific	JJ
cord-355413-ls2nud43	221	2	anatomical	anatomical	JJ
cord-355413-ls2nud43	221	3	factions	faction	NNS
cord-355413-ls2nud43	221	4	within	within	IN
cord-355413-ls2nud43	221	5	the	the	DT
cord-355413-ls2nud43	221	6	CNS	CNS	NNP
cord-355413-ls2nud43	221	7	should	should	MD
cord-355413-ls2nud43	221	8	also	also	RB
cord-355413-ls2nud43	221	9	be	be	VB
cord-355413-ls2nud43	221	10	considered	consider	VBN
cord-355413-ls2nud43	221	11	.	.	.
cord-355413-ls2nud43	222	1	Furthermore	furthermore	RB
cord-355413-ls2nud43	222	2	,	,	,
cord-355413-ls2nud43	222	3	effort	effort	NN
cord-355413-ls2nud43	222	4	must	must	MD
cord-355413-ls2nud43	222	5	be	be	VB
cord-355413-ls2nud43	222	6	taken	take	VBN
cord-355413-ls2nud43	222	7	in	in	IN
cord-355413-ls2nud43	222	8	suppressing	suppress	VBG
cord-355413-ls2nud43	222	9	the	the	DT
cord-355413-ls2nud43	222	10	capacity	capacity	NN
cord-355413-ls2nud43	222	11	of	of	IN
cord-355413-ls2nud43	222	12	certain	certain	JJ
cord-355413-ls2nud43	222	13	tumours	tumour	NNS
cord-355413-ls2nud43	222	14	to	to	IN
cord-355413-ls2nud43	222	15	down	down	RB
cord-355413-ls2nud43	222	16	-	-	HYPH
cord-355413-ls2nud43	222	17	regulate	regulate	VB
cord-355413-ls2nud43	222	18	activating	activate	VBG
cord-355413-ls2nud43	222	19	signals	signal	NNS
cord-355413-ls2nud43	222	20	and	and	CC
cord-355413-ls2nud43	222	21	production	production	NN
cord-355413-ls2nud43	222	22	of	of	IN
cord-355413-ls2nud43	222	23	inhibitory	inhibitory	JJ
cord-355413-ls2nud43	222	24	proteins	protein	NNS
cord-355413-ls2nud43	222	25	against	against	IN
cord-355413-ls2nud43	222	26	NK	NK	NNP
cord-355413-ls2nud43	222	27	cells	cell	NNS
cord-355413-ls2nud43	222	28	.	.	.
cord-355413-ls2nud43	223	1	During	during	IN
cord-355413-ls2nud43	223	2	CNS	CNS	NNP
cord-355413-ls2nud43	223	3	infection	infection	NN
cord-355413-ls2nud43	223	4	,	,	,
cord-355413-ls2nud43	223	5	cytolytic	cytolytic	JJ
cord-355413-ls2nud43	223	6	activity	activity	NN
cord-355413-ls2nud43	223	7	of	of	IN
cord-355413-ls2nud43	223	8	NK	NK	NNP
cord-355413-ls2nud43	223	9	cells	cell	NNS
cord-355413-ls2nud43	223	10	contributes	contribute	VBZ
cord-355413-ls2nud43	223	11	to	to	IN
cord-355413-ls2nud43	223	12	elimination	elimination	NN
cord-355413-ls2nud43	223	13	of	of	IN
cord-355413-ls2nud43	223	14	viral	viral	JJ
cord-355413-ls2nud43	223	15	and	and	CC
cord-355413-ls2nud43	223	16	bacterial	bacterial	JJ
cord-355413-ls2nud43	223	17	infected	infected	JJ
cord-355413-ls2nud43	223	18	cells	cell	NNS
cord-355413-ls2nud43	223	19	and	and	CC
cord-355413-ls2nud43	223	20	controls	control	VBZ
cord-355413-ls2nud43	223	21	the	the	DT
cord-355413-ls2nud43	223	22	magnitude	magnitude	NN
cord-355413-ls2nud43	223	23	of	of	IN
cord-355413-ls2nud43	223	24	inflammation	inflammation	NN
cord-355413-ls2nud43	223	25	.	.	.
cord-355413-ls2nud43	224	1	Debris	debris	NN
cord-355413-ls2nud43	224	2	from	from	IN
cord-355413-ls2nud43	224	3	neuronal	neuronal	JJ
cord-355413-ls2nud43	224	4	and/or	and/or	CC
cord-355413-ls2nud43	224	5	glial	glial	JJ
cord-355413-ls2nud43	224	6	cell	cell	NN
cord-355413-ls2nud43	224	7	death	death	NN
cord-355413-ls2nud43	224	8	is	be	VBZ
cord-355413-ls2nud43	224	9	taken	take	VBN
cord-355413-ls2nud43	224	10	up	up	RP
cord-355413-ls2nud43	224	11	by	by	IN
cord-355413-ls2nud43	224	12	antigen	antigen	NN
cord-355413-ls2nud43	224	13	-	-	HYPH
cord-355413-ls2nud43	224	14	presenting	present	VBG
cord-355413-ls2nud43	224	15	cells	cell	NNS
cord-355413-ls2nud43	224	16	(	(	-LRB-
cord-355413-ls2nud43	224	17	APCs	apc	NNS
cord-355413-ls2nud43	224	18	)	)	-RRB-
cord-355413-ls2nud43	224	19	and	and	CC
cord-355413-ls2nud43	224	20	presentation	presentation	NN
cord-355413-ls2nud43	224	21	to	to	IN
cord-355413-ls2nud43	224	22	T	t	NN
cord-355413-ls2nud43	224	23	cells	cell	NNS
cord-355413-ls2nud43	224	24	.	.	.
cord-355413-ls2nud43	225	1	Cytokine	cytokine	NN
cord-355413-ls2nud43	225	2	(	(	-LRB-
cord-355413-ls2nud43	225	3	IFN-	ifn-	NN
cord-355413-ls2nud43	225	4	)	)	-RRB-
cord-355413-ls2nud43	225	5	secretion	secretion	NN
cord-355413-ls2nud43	225	6	by	by	IN
cord-355413-ls2nud43	225	7	NK	NK	NNP
cord-355413-ls2nud43	225	8	cells	cell	NNS
cord-355413-ls2nud43	225	9	increases	increase	VBZ
cord-355413-ls2nud43	225	10	MHC	MHC	NNP
cord-355413-ls2nud43	225	11	class	class	NN
cord-355413-ls2nud43	225	12	II	ii	CD
cord-355413-ls2nud43	225	13	expression	expression	NN
cord-355413-ls2nud43	225	14	by	by	IN
cord-355413-ls2nud43	225	15	APC	APC	NNP
cord-355413-ls2nud43	225	16	and	and	CC
cord-355413-ls2nud43	225	17	,	,	,
cord-355413-ls2nud43	225	18	thus	thus	RB
cord-355413-ls2nud43	225	19	,	,	,
cord-355413-ls2nud43	225	20	favours	favour	VBZ
cord-355413-ls2nud43	225	21	generation	generation	NN
cord-355413-ls2nud43	225	22	of	of	IN
cord-355413-ls2nud43	225	23	Th1	th1	CD
cord-355413-ls2nud43	225	24	type	type	NN
cord-355413-ls2nud43	225	25	of	of	IN
cord-355413-ls2nud43	225	26	T	T	NNP
cord-355413-ls2nud43	225	27	helper	helper	NN
cord-355413-ls2nud43	225	28	cells	cell	NNS
cord-355413-ls2nud43	225	29	.	.	.
cord-355413-ls2nud43	226	1	Thus	thus	RB
cord-355413-ls2nud43	226	2	,	,	,
cord-355413-ls2nud43	226	3	NK	NK	NNP
cord-355413-ls2nud43	226	4	cells	cell	NNS
cord-355413-ls2nud43	226	5	function	function	VBP
cord-355413-ls2nud43	226	6	not	not	RB
cord-355413-ls2nud43	226	7	only	only	RB
cord-355413-ls2nud43	226	8	as	as	IN
cord-355413-ls2nud43	226	9	the	the	DT
cord-355413-ls2nud43	226	10	initial	initial	JJ
cord-355413-ls2nud43	226	11	line	line	NN
cord-355413-ls2nud43	226	12	of	of	IN
cord-355413-ls2nud43	226	13	host	host	NN
cord-355413-ls2nud43	226	14	defence	defence	NN
cord-355413-ls2nud43	226	15	,	,	,
cord-355413-ls2nud43	226	16	but	but	CC
cord-355413-ls2nud43	226	17	also	also	RB
cord-355413-ls2nud43	226	18	as	as	IN
cord-355413-ls2nud43	226	19	fuel	fuel	NN
cord-355413-ls2nud43	226	20	to	to	IN
cord-355413-ls2nud43	226	21	the	the	DT
cord-355413-ls2nud43	226	22	generation	generation	NN
cord-355413-ls2nud43	226	23	of	of	IN
cord-355413-ls2nud43	226	24	adaptive	adaptive	JJ
cord-355413-ls2nud43	226	25	immune	immune	JJ
cord-355413-ls2nud43	226	26	responses	response	NNS
cord-355413-ls2nud43	226	27	.	.	.
cord-355413-ls2nud43	227	1	Overall	overall	RB
cord-355413-ls2nud43	227	2	,	,	,
cord-355413-ls2nud43	227	3	NK	NK	NNP
cord-355413-ls2nud43	227	4	cells	cell	NNS
cord-355413-ls2nud43	227	5	are	be	VBP
cord-355413-ls2nud43	227	6	expected	expect	VBN
cord-355413-ls2nud43	227	7	to	to	TO
cord-355413-ls2nud43	227	8	boost	boost	VB
cord-355413-ls2nud43	227	9	immune	immune	JJ
cord-355413-ls2nud43	227	10	response	response	NN
cord-355413-ls2nud43	227	11	within	within	IN
cord-355413-ls2nud43	227	12	the	the	DT
cord-355413-ls2nud43	227	13	CNS	CNS	NNP
cord-355413-ls2nud43	227	14	.	.	.
cord-355413-ls2nud43	228	1	Paradoxically	paradoxically	RB
cord-355413-ls2nud43	228	2	,	,	,
cord-355413-ls2nud43	228	3	emerging	emerge	VBG
cord-355413-ls2nud43	228	4	evidence	evidence	NN
cord-355413-ls2nud43	228	5	suggests	suggest	VBZ
cord-355413-ls2nud43	228	6	that	that	IN
cord-355413-ls2nud43	228	7	NK	NK	NNP
cord-355413-ls2nud43	228	8	cells	cell	NNS
cord-355413-ls2nud43	228	9	can	can	MD
cord-355413-ls2nud43	228	10	inhibit	inhibit	VB
cord-355413-ls2nud43	228	11	CNS	CNS	NNP
cord-355413-ls2nud43	228	12	inflammation	inflammation	NN
cord-355413-ls2nud43	228	13	and	and	CC
cord-355413-ls2nud43	228	14	control	control	VB
cord-355413-ls2nud43	228	15	the	the	DT
cord-355413-ls2nud43	228	16	magnitude	magnitude	NN
cord-355413-ls2nud43	228	17	of	of	IN
cord-355413-ls2nud43	228	18	autoimmunity	autoimmunity	NN
cord-355413-ls2nud43	228	19	(	(	-LRB-
cord-355413-ls2nud43	228	20	Table	Table	NNP
cord-355413-ls2nud43	228	21	28	28	CD
cord-355413-ls2nud43	228	22	.2	.2	CD
cord-355413-ls2nud43	228	23	)	)	-RRB-
cord-355413-ls2nud43	228	24	.	.	.
cord-355413-ls2nud43	229	1	MS	MS	NNP
cord-355413-ls2nud43	229	2	is	be	VBZ
cord-355413-ls2nud43	229	3	a	a	DT
cord-355413-ls2nud43	229	4	classic	classic	JJ
cord-355413-ls2nud43	229	5	autoimmune	autoimmune	JJ
cord-355413-ls2nud43	229	6	disease	disease	NN
cord-355413-ls2nud43	229	7	characterized	characterize	VBN
cord-355413-ls2nud43	229	8	by	by	IN
cord-355413-ls2nud43	229	9	extensive	extensive	JJ
cord-355413-ls2nud43	229	10	CNS	CNS	NNP
cord-355413-ls2nud43	229	11	inflammation	inflammation	NN
cord-355413-ls2nud43	229	12	and	and	CC
cord-355413-ls2nud43	229	13	immune	immune	NN
cord-355413-ls2nud43	229	14	-	-	HYPH
cord-355413-ls2nud43	229	15	mediated	mediate	VBN
cord-355413-ls2nud43	229	16	destruction	destruction	NN
cord-355413-ls2nud43	229	17	of	of	IN
cord-355413-ls2nud43	229	18	myelin	myelin	NN
cord-355413-ls2nud43	229	19	.	.	.
cord-355413-ls2nud43	230	1	Consequently	consequently	RB
cord-355413-ls2nud43	230	2	,	,	,
cord-355413-ls2nud43	230	3	the	the	DT
cord-355413-ls2nud43	230	4	function	function	NN
cord-355413-ls2nud43	230	5	of	of	IN
cord-355413-ls2nud43	230	6	myelin	myelin	NN
cord-355413-ls2nud43	230	7	sheaths	sheath	NNS
cord-355413-ls2nud43	230	8	becomes	become	VBZ
cord-355413-ls2nud43	230	9	compromised	compromised	JJ
cord-355413-ls2nud43	230	10	and	and	CC
cord-355413-ls2nud43	230	11	neurological	neurological	JJ
cord-355413-ls2nud43	230	12	impairment	impairment	NN
cord-355413-ls2nud43	230	13	occurs	occur	VBZ
cord-355413-ls2nud43	230	14	.	.	.
cord-355413-ls2nud43	231	1	The	the	DT
cord-355413-ls2nud43	231	2	pathogenesis	pathogenesis	NN
cord-355413-ls2nud43	231	3	of	of	IN
cord-355413-ls2nud43	231	4	MS	MS	NNP
cord-355413-ls2nud43	231	5	is	be	VBZ
cord-355413-ls2nud43	231	6	mirrored	mirror	VBN
cord-355413-ls2nud43	231	7	,	,	,
cord-355413-ls2nud43	231	8	in	in	IN
cord-355413-ls2nud43	231	9	part	part	NN
cord-355413-ls2nud43	231	10	,	,	,
cord-355413-ls2nud43	231	11	in	in	IN
cord-355413-ls2nud43	231	12	EAE	EAE	NNP
cord-355413-ls2nud43	231	13	,	,	,
cord-355413-ls2nud43	231	14	which	which	WDT
cord-355413-ls2nud43	231	15	can	can	MD
cord-355413-ls2nud43	231	16	be	be	VB
cord-355413-ls2nud43	231	17	induced	induce	VBN
cord-355413-ls2nud43	231	18	in	in	IN
cord-355413-ls2nud43	231	19	susceptible	susceptible	JJ
cord-355413-ls2nud43	231	20	strains	strain	NNS
cord-355413-ls2nud43	231	21	of	of	IN
cord-355413-ls2nud43	231	22	mice	mouse	NNS
cord-355413-ls2nud43	231	23	with	with	IN
cord-355413-ls2nud43	231	24	neuron	neuron	NN
cord-355413-ls2nud43	231	25	-	-	HYPH
cord-355413-ls2nud43	231	26	antigens	antigen	NNS
cord-355413-ls2nud43	231	27	and	and	CC
cord-355413-ls2nud43	231	28	complete	complete	VB
cord-355413-ls2nud43	231	29	Freund	Freund	NNP
cord-355413-ls2nud43	231	30	's	's	POS
cord-355413-ls2nud43	231	31	adjuvant	adjuvant	NN
cord-355413-ls2nud43	231	32	.	.	.
cord-355413-ls2nud43	232	1	The	the	DT
cord-355413-ls2nud43	232	2	roles	role	NNS
cord-355413-ls2nud43	232	3	of	of	IN
cord-355413-ls2nud43	232	4	NK	NK	NNP
cord-355413-ls2nud43	232	5	cells	cell	NNS
cord-355413-ls2nud43	232	6	in	in	IN
cord-355413-ls2nud43	232	7	the	the	DT
cord-355413-ls2nud43	232	8	pathogenesis	pathogenesis	NN
cord-355413-ls2nud43	232	9	of	of	IN
cord-355413-ls2nud43	232	10	MS	MS	NNP
cord-355413-ls2nud43	232	11	and	and	CC
cord-355413-ls2nud43	232	12	EAE	EAE	NNP
cord-355413-ls2nud43	232	13	have	have	VBP
cord-355413-ls2nud43	232	14	been	be	VBN
cord-355413-ls2nud43	232	15	investigated	investigate	VBN
cord-355413-ls2nud43	232	16	.	.	.
cord-355413-ls2nud43	233	1	In	in	IN
cord-355413-ls2nud43	233	2	patients	patient	NNS
cord-355413-ls2nud43	233	3	with	with	IN
cord-355413-ls2nud43	233	4	MS	MS	NNP
cord-355413-ls2nud43	233	5	,	,	,
cord-355413-ls2nud43	233	6	NK	NK	NNP
cord-355413-ls2nud43	233	7	cells	cell	NNS
cord-355413-ls2nud43	233	8	(	(	-LRB-
cord-355413-ls2nud43	233	9	CD56	CD56	NNP
cord-355413-ls2nud43	233	10	and	and	CC
cord-355413-ls2nud43	233	11	CD57	CD57	NNP
cord-355413-ls2nud43	233	12	)	)	-RRB-
cord-355413-ls2nud43	233	13	are	be	VBP
cord-355413-ls2nud43	233	14	present	present	JJ
cord-355413-ls2nud43	233	15	in	in	IN
cord-355413-ls2nud43	233	16	the	the	DT
cord-355413-ls2nud43	233	17	peripheral	peripheral	JJ
cord-355413-ls2nud43	233	18	blood	blood	NN
cord-355413-ls2nud43	233	19	with	with	IN
cord-355413-ls2nud43	233	20	reduced	reduced	JJ
cord-355413-ls2nud43	233	21	numbers	number	NNS
cord-355413-ls2nud43	233	22	and	and	CC
cord-355413-ls2nud43	233	23	cytolytic	cytolytic	JJ
cord-355413-ls2nud43	233	24	activity	activity	NN
cord-355413-ls2nud43	234	1	(	(	-LRB-
cord-355413-ls2nud43	234	2	Shibatomi	Shibatomi	NNP
cord-355413-ls2nud43	234	3	et	et	FW
cord-355413-ls2nud43	234	4	al	al	NNP
cord-355413-ls2nud43	234	5	.	.	NNP
cord-355413-ls2nud43	234	6	,	,	,
cord-355413-ls2nud43	234	7	2001	2001	CD
cord-355413-ls2nud43	235	1	;	;	:
cord-355413-ls2nud43	235	2	Trinchieri	Trinchieri	NNP
cord-355413-ls2nud43	235	3	,	,	,
cord-355413-ls2nud43	235	4	1989	1989	CD
cord-355413-ls2nud43	235	5	)	)	-RRB-
cord-355413-ls2nud43	235	6	.	.	.
cord-355413-ls2nud43	236	1	This	this	DT
cord-355413-ls2nud43	236	2	finding	finding	NN
cord-355413-ls2nud43	236	3	is	be	VBZ
cord-355413-ls2nud43	236	4	not	not	RB
cord-355413-ls2nud43	236	5	unique	unique	JJ
cord-355413-ls2nud43	236	6	to	to	IN
cord-355413-ls2nud43	236	7	MS	MS	NNP
cord-355413-ls2nud43	236	8	and	and	CC
cord-355413-ls2nud43	236	9	similar	similar	JJ
cord-355413-ls2nud43	236	10	phenotype	phenotype	NN
cord-355413-ls2nud43	236	11	of	of	IN
cord-355413-ls2nud43	236	12	NK	NK	NNP
cord-355413-ls2nud43	236	13	cells	cell	NNS
cord-355413-ls2nud43	236	14	have	have	VBP
cord-355413-ls2nud43	236	15	been	be	VBN
cord-355413-ls2nud43	236	16	documented	document	VBN
cord-355413-ls2nud43	236	17	in	in	IN
cord-355413-ls2nud43	236	18	many	many	JJ
cord-355413-ls2nud43	236	19	other	other	JJ
cord-355413-ls2nud43	236	20	types	type	NNS
cord-355413-ls2nud43	236	21	of	of	IN
cord-355413-ls2nud43	236	22	autoimmune	autoimmune	JJ
cord-355413-ls2nud43	236	23	diseases	disease	NNS
cord-355413-ls2nud43	236	24	such	such	JJ
cord-355413-ls2nud43	236	25	as	as	IN
cord-355413-ls2nud43	236	26	rheumatoid	rheumatoid	NN
cord-355413-ls2nud43	236	27	arthritis	arthritis	NN
cord-355413-ls2nud43	236	28	,	,	,
cord-355413-ls2nud43	236	29	systemic	systemic	JJ
cord-355413-ls2nud43	236	30	lupus	lupus	NN
cord-355413-ls2nud43	236	31	erythematosus	erythematosus	NN
cord-355413-ls2nud43	236	32	,	,	,
cord-355413-ls2nud43	236	33	myasthenia	myasthenia	NN
cord-355413-ls2nud43	236	34	gravis	gravis	NN
cord-355413-ls2nud43	236	35	,	,	,
cord-355413-ls2nud43	236	36	etc	etc	FW
cord-355413-ls2nud43	237	1	(	(	-LRB-
cord-355413-ls2nud43	237	2	Shibatomi	Shibatomi	NNP
cord-355413-ls2nud43	237	3	et	et	FW
cord-355413-ls2nud43	237	4	al	al	NNP
cord-355413-ls2nud43	237	5	.	.	NNP
cord-355413-ls2nud43	237	6	,	,	,
cord-355413-ls2nud43	237	7	2001	2001	CD
cord-355413-ls2nud43	237	8	)	)	-RRB-
cord-355413-ls2nud43	237	9	.	.	.
cord-355413-ls2nud43	238	1	In	in	IN
cord-355413-ls2nud43	238	2	parallel	parallel	NN
cord-355413-ls2nud43	238	3	,	,	,
cord-355413-ls2nud43	238	4	patients	patient	NNS
cord-355413-ls2nud43	238	5	with	with	IN
cord-355413-ls2nud43	238	6	MS	MS	NNP
cord-355413-ls2nud43	238	7	and	and	CC
cord-355413-ls2nud43	238	8	other	other	JJ
cord-355413-ls2nud43	238	9	autoimmune	autoimmune	JJ
cord-355413-ls2nud43	238	10	diseases	disease	NNS
cord-355413-ls2nud43	238	11	have	have	VBP
cord-355413-ls2nud43	238	12	defective	defective	JJ
cord-355413-ls2nud43	238	13	functions	function	NNS
cord-355413-ls2nud43	238	14	of	of	IN
cord-355413-ls2nud43	238	15	'	'	``
cord-355413-ls2nud43	238	16	regulatory	regulatory	JJ
cord-355413-ls2nud43	238	17	cells	cell	NNS
cord-355413-ls2nud43	238	18	'	'	POS
cord-355413-ls2nud43	238	19	,	,	,
cord-355413-ls2nud43	238	20	including	include	VBG
cord-355413-ls2nud43	238	21	NKT	NKT	NNP
cord-355413-ls2nud43	238	22	cells	cell	NNS
cord-355413-ls2nud43	238	23	and	and	CC
cord-355413-ls2nud43	238	24	CD4	CD4	NNP
cord-355413-ls2nud43	238	25			NNP
cord-355413-ls2nud43	238	26	CD25	CD25	NNP
cord-355413-ls2nud43	238	27			NNP
cord-355413-ls2nud43	238	28	regulatory	regulatory	JJ
cord-355413-ls2nud43	238	29	T	t	NN
cord-355413-ls2nud43	238	30	cells	cell	NNS
cord-355413-ls2nud43	238	31	(	(	-LRB-
cord-355413-ls2nud43	238	32	Treg	Treg	NNP
cord-355413-ls2nud43	238	33	)	)	-RRB-
cord-355413-ls2nud43	239	1	(	(	-LRB-
cord-355413-ls2nud43	239	2	La	La	NNP
cord-355413-ls2nud43	239	3	Cava	Cava	NNP
cord-355413-ls2nud43	239	4	et	et	FW
cord-355413-ls2nud43	239	5	al	al	NNP
cord-355413-ls2nud43	239	6	.	.	NNP
cord-355413-ls2nud43	239	7	,	,	,
cord-355413-ls2nud43	239	8	2006	2006	CD
cord-355413-ls2nud43	239	9	)	)	-RRB-
cord-355413-ls2nud43	239	10	.	.	.
cord-355413-ls2nud43	240	1	A	a	DT
cord-355413-ls2nud43	240	2	reduced	reduced	JJ
cord-355413-ls2nud43	240	3	number	number	NN
cord-355413-ls2nud43	240	4	and/or	and/or	CC
cord-355413-ls2nud43	240	5	compromised	compromised	JJ
cord-355413-ls2nud43	240	6	function	function	NN
cord-355413-ls2nud43	240	7	of	of	IN
cord-355413-ls2nud43	240	8	NK	NK	NNP
cord-355413-ls2nud43	240	9	cells	cell	NNS
cord-355413-ls2nud43	240	10	,	,	,
cord-355413-ls2nud43	240	11	NKT	NKT	NNP
cord-355413-ls2nud43	240	12	cells	cell	NNS
cord-355413-ls2nud43	240	13	and	and	CC
cord-355413-ls2nud43	240	14	Treg	Treg	NNP
cord-355413-ls2nud43	240	15	cells	cell	NNS
cord-355413-ls2nud43	240	16	invite	invite	VBP
cord-355413-ls2nud43	240	17	a	a	DT
cord-355413-ls2nud43	240	18	hypothesis	hypothesis	NN
cord-355413-ls2nud43	240	19	that	that	IN
cord-355413-ls2nud43	240	20	autoimmunity	autoimmunity	NN
cord-355413-ls2nud43	240	21	is	be	VBZ
cord-355413-ls2nud43	240	22	associated	associate	VBN
cord-355413-ls2nud43	240	23	with	with	IN
cord-355413-ls2nud43	240	24	a	a	DT
cord-355413-ls2nud43	240	25	result	result	NN
cord-355413-ls2nud43	240	26	of	of	IN
cord-355413-ls2nud43	240	27	global	global	JJ
cord-355413-ls2nud43	240	28	defective	defective	JJ
cord-355413-ls2nud43	240	29	regulatory	regulatory	JJ
cord-355413-ls2nud43	240	30	cell	cell	NN
cord-355413-ls2nud43	240	31	functions	function	NNS
cord-355413-ls2nud43	240	32	in	in	IN
cord-355413-ls2nud43	240	33	these	these	DT
cord-355413-ls2nud43	240	34	patients	patient	NNS
cord-355413-ls2nud43	240	35	.	.	.
cord-355413-ls2nud43	241	1	This	this	DT
cord-355413-ls2nud43	241	2	hypothesis	hypothesis	NN
cord-355413-ls2nud43	241	3	has	have	VBZ
cord-355413-ls2nud43	241	4	been	be	VBN
cord-355413-ls2nud43	241	5	tested	test	VBN
cord-355413-ls2nud43	241	6	in	in	IN
cord-355413-ls2nud43	241	7	several	several	JJ
cord-355413-ls2nud43	241	8	EAE	EAE	NNP
cord-355413-ls2nud43	241	9	models	model	NNS
cord-355413-ls2nud43	241	10	.	.	.
cord-355413-ls2nud43	242	1	Because	because	IN
cord-355413-ls2nud43	242	2	gene	gene	NN
cord-355413-ls2nud43	242	3	encoding	encoding	NN
cord-355413-ls2nud43	242	4	NK	NK	NNP
cord-355413-ls2nud43	242	5	cells	cell	NNS
cord-355413-ls2nud43	242	6	can	can	MD
cord-355413-ls2nud43	242	7	not	not	RB
cord-355413-ls2nud43	242	8	be	be	VB
cord-355413-ls2nud43	242	9	targeted	target	VBN
cord-355413-ls2nud43	242	10	by	by	IN
cord-355413-ls2nud43	242	11	the	the	DT
cord-355413-ls2nud43	242	12	current	current	JJ
cord-355413-ls2nud43	242	13	technology	technology	NN
cord-355413-ls2nud43	242	14	,	,	,
cord-355413-ls2nud43	242	15	several	several	JJ
cord-355413-ls2nud43	242	16	depleting	deplete	VBG
cord-355413-ls2nud43	242	17	antibodies	antibody	NNS
cord-355413-ls2nud43	242	18	have	have	VBP
cord-355413-ls2nud43	242	19	been	be	VBN
cord-355413-ls2nud43	242	20	used	use	VBN
cord-355413-ls2nud43	242	21	to	to	TO
cord-355413-ls2nud43	242	22	study	study	VB
cord-355413-ls2nud43	242	23	the	the	DT
cord-355413-ls2nud43	242	24	function	function	NN
cord-355413-ls2nud43	242	25	of	of	IN
cord-355413-ls2nud43	242	26	NK	NK	NNP
cord-355413-ls2nud43	242	27	cells	cell	NNS
cord-355413-ls2nud43	242	28	in	in	IN
cord-355413-ls2nud43	242	29	vivo	vivo	NN
cord-355413-ls2nud43	242	30	.	.	.
cord-355413-ls2nud43	243	1	Several	several	JJ
cord-355413-ls2nud43	243	2	groups	group	NNS
cord-355413-ls2nud43	243	3	have	have	VBP
cord-355413-ls2nud43	243	4	utilized	utilize	VBN
cord-355413-ls2nud43	243	5	anti	anti	JJ
cord-355413-ls2nud43	243	6	-	-	JJ
cord-355413-ls2nud43	243	7	NK1.1	nk1.1	JJ
cord-355413-ls2nud43	243	8	mAb	mAb	NNS
cord-355413-ls2nud43	243	9	and	and	CC
cord-355413-ls2nud43	243	10	observed	observe	VBD
cord-355413-ls2nud43	243	11	that	that	IN
cord-355413-ls2nud43	243	12	depletion	depletion	NN
cord-355413-ls2nud43	243	13	of	of	IN
cord-355413-ls2nud43	243	14	NK	NK	NNP
cord-355413-ls2nud43	243	15	cells	cell	NNS
cord-355413-ls2nud43	243	16	by	by	IN
cord-355413-ls2nud43	243	17	injecting	inject	VBG
cord-355413-ls2nud43	243	18	anti	anti	JJ
cord-355413-ls2nud43	243	19	-	-	JJ
cord-355413-ls2nud43	243	20	NK1.1	nk1.1	JJ
cord-355413-ls2nud43	243	21	mAb	mab	NN
cord-355413-ls2nud43	243	22	leads	lead	VBZ
cord-355413-ls2nud43	243	23	to	to	IN
cord-355413-ls2nud43	243	24	exacerbation	exacerbation	NN
cord-355413-ls2nud43	243	25	of	of	IN
cord-355413-ls2nud43	243	26	EAE	EAE	NNP
cord-355413-ls2nud43	243	27	(	(	-LRB-
cord-355413-ls2nud43	243	28	Zhang	Zhang	NNP
cord-355413-ls2nud43	243	29	et	et	NNP
cord-355413-ls2nud43	243	30	al	al	NNP
cord-355413-ls2nud43	243	31	.	.	NNP
cord-355413-ls2nud43	243	32	,	,	,
cord-355413-ls2nud43	243	33	1997	1997	CD
cord-355413-ls2nud43	243	34	)	)	-RRB-
cord-355413-ls2nud43	243	35	.	.	.
cord-355413-ls2nud43	244	1	Apparently	apparently	RB
cord-355413-ls2nud43	244	2	,	,	,
cord-355413-ls2nud43	244	3	both	both	CC
cord-355413-ls2nud43	244	4	peripheral	peripheral	JJ
cord-355413-ls2nud43	244	5	and	and	CC
cord-355413-ls2nud43	244	6	CNS	CNS	NNP
cord-355413-ls2nud43	244	7	NK	NK	NNP
cord-355413-ls2nud43	244	8	cells	cell	NNS
cord-355413-ls2nud43	244	9	are	be	VBP
cord-355413-ls2nud43	244	10	absent	absent	JJ
cord-355413-ls2nud43	244	11	in	in	IN
cord-355413-ls2nud43	244	12	this	this	DT
cord-355413-ls2nud43	244	13	experimental	experimental	JJ
cord-355413-ls2nud43	244	14	system	system	NN
cord-355413-ls2nud43	244	15	.	.	.
cord-355413-ls2nud43	245	1	It	-PRON-	PRP
cord-355413-ls2nud43	245	2	is	be	VBZ
cord-355413-ls2nud43	245	3	,	,	,
cord-355413-ls2nud43	245	4	therefore	therefore	RB
cord-355413-ls2nud43	245	5	,	,	,
cord-355413-ls2nud43	245	6	not	not	RB
cord-355413-ls2nud43	245	7	possible	possible	JJ
cord-355413-ls2nud43	245	8	to	to	TO
cord-355413-ls2nud43	245	9	differentiate	differentiate	VB
cord-355413-ls2nud43	245	10	the	the	DT
cord-355413-ls2nud43	245	11	role	role	NN
cord-355413-ls2nud43	245	12	of	of	IN
cord-355413-ls2nud43	245	13	NK	NK	NNP
cord-355413-ls2nud43	245	14	cells	cell	NNS
cord-355413-ls2nud43	245	15	in	in	IN
cord-355413-ls2nud43	245	16	the	the	DT
cord-355413-ls2nud43	245	17	periphery	periphery	NN
cord-355413-ls2nud43	245	18	and	and	CC
cord-355413-ls2nud43	245	19	in	in	IN
cord-355413-ls2nud43	245	20	the	the	DT
cord-355413-ls2nud43	245	21	CNS	CNS	NNP
cord-355413-ls2nud43	245	22	.	.	.
cord-355413-ls2nud43	246	1	NK	NK	NNP
cord-355413-ls2nud43	246	2	cell	cell	NN
cord-355413-ls2nud43	246	3	homing	homing	NN
cord-355413-ls2nud43	246	4	to	to	IN
cord-355413-ls2nud43	246	5	CNS	CNS	NNP
cord-355413-ls2nud43	246	6	is	be	VBZ
cord-355413-ls2nud43	246	7	controlled	control	VBN
cord-355413-ls2nud43	246	8	by	by	IN
cord-355413-ls2nud43	246	9	a	a	DT
cord-355413-ls2nud43	246	10	specific	specific	JJ
cord-355413-ls2nud43	246	11	chemokine	chemokine	NN
cord-355413-ls2nud43	246	12	receptor	receptor	NN
cord-355413-ls2nud43	246	13	ligand	ligand	NN
cord-355413-ls2nud43	246	14	pathway	pathway	NN
cord-355413-ls2nud43	246	15	involving	involve	VBG
cord-355413-ls2nud43	246	16	CX3CR1	CX3CR1	NNP
cord-355413-ls2nud43	246	17	and	and	CC
cord-355413-ls2nud43	246	18	fractalkine	fractalkine	NN
cord-355413-ls2nud43	246	19	(	(	-LRB-
cord-355413-ls2nud43	246	20	CX3CL1	cx3cl1	NN
cord-355413-ls2nud43	246	21	)	)	-RRB-
cord-355413-ls2nud43	246	22	.	.	.
cord-355413-ls2nud43	247	1	CX3CR1	CX3CR1	NNP
cord-355413-ls2nud43	247	2	is	be	VBZ
cord-355413-ls2nud43	247	3	expressed	express	VBN
cord-355413-ls2nud43	247	4	almost	almost	RB
cord-355413-ls2nud43	247	5	exclusively	exclusively	RB
cord-355413-ls2nud43	247	6	by	by	IN
cord-355413-ls2nud43	247	7	CNS	cns	JJ
cord-355413-ls2nud43	247	8	glial	glial	NN
cord-355413-ls2nud43	247	9	cells	cell	NNS
cord-355413-ls2nud43	247	10	(	(	-LRB-
cord-355413-ls2nud43	247	11	Boehme	Boehme	NNP
cord-355413-ls2nud43	247	12	et	et	NNP
cord-355413-ls2nud43	247	13	al	al	NNP
cord-355413-ls2nud43	247	14	.	.	NNP
cord-355413-ls2nud43	247	15	,	,	,
cord-355413-ls2nud43	247	16	2000	2000	CD
cord-355413-ls2nud43	247	17	;	;	:
cord-355413-ls2nud43	247	18	Cardona	Cardona	NNP
cord-355413-ls2nud43	247	19	et	et	NNP
cord-355413-ls2nud43	247	20	al	al	NNP
cord-355413-ls2nud43	247	21	.	.	NNP
cord-355413-ls2nud43	247	22	,	,	,
cord-355413-ls2nud43	247	23	2006	2006	CD
cord-355413-ls2nud43	247	24	)	)	-RRB-
cord-355413-ls2nud43	247	25	.	.	.
cord-355413-ls2nud43	248	1	Thus	thus	RB
cord-355413-ls2nud43	248	2	,	,	,
cord-355413-ls2nud43	248	3	germ	germ	NN
cord-355413-ls2nud43	248	4	-	-	HYPH
cord-355413-ls2nud43	248	5	line	line	NN
cord-355413-ls2nud43	248	6	deletion	deletion	NN
cord-355413-ls2nud43	248	7	of	of	IN
cord-355413-ls2nud43	248	8	CX3CR1	CX3CR1	NNP
cord-355413-ls2nud43	248	9	leads	lead	VBZ
cord-355413-ls2nud43	248	10	to	to	IN
cord-355413-ls2nud43	248	11	impaired	impaired	JJ
cord-355413-ls2nud43	248	12	homing	homing	NN
cord-355413-ls2nud43	248	13	of	of	IN
cord-355413-ls2nud43	248	14	NK	NK	NNP
cord-355413-ls2nud43	248	15	cells	cell	NNS
cord-355413-ls2nud43	248	16	to	to	IN
cord-355413-ls2nud43	248	17	the	the	DT
cord-355413-ls2nud43	248	18	CNS	CNS	NNP
cord-355413-ls2nud43	248	19	.	.	.
cord-355413-ls2nud43	249	1	This	this	DT
cord-355413-ls2nud43	249	2	model	model	NN
cord-355413-ls2nud43	249	3	would	would	MD
cord-355413-ls2nud43	249	4	be	be	VB
cord-355413-ls2nud43	249	5	ideal	ideal	JJ
cord-355413-ls2nud43	249	6	in	in	IN
cord-355413-ls2nud43	249	7	addressing	address	VBG
cord-355413-ls2nud43	249	8	CNS	CNS	NNP
cord-355413-ls2nud43	249	9	inflammation	inflammation	NN
cord-355413-ls2nud43	249	10	/	/	SYM
cord-355413-ls2nud43	249	11	autoimmunity	autoimmunity	NN
cord-355413-ls2nud43	249	12	in	in	IN
cord-355413-ls2nud43	249	13	relation	relation	NN
cord-355413-ls2nud43	249	14	to	to	IN
cord-355413-ls2nud43	249	15	NK	NK	NNP
cord-355413-ls2nud43	249	16	cells	cell	NNS
cord-355413-ls2nud43	249	17	.	.	.
cord-355413-ls2nud43	250	1	Interestingly	interestingly	RB
cord-355413-ls2nud43	250	2	,	,	,
cord-355413-ls2nud43	250	3	upon	upon	IN
cord-355413-ls2nud43	250	4	immunization	immunization	NN
cord-355413-ls2nud43	250	5	,	,	,
cord-355413-ls2nud43	250	6	CX3CR1-deficient	cx3cr1-deficient	JJ
cord-355413-ls2nud43	250	7	mice	mouse	NNS
cord-355413-ls2nud43	250	8	with	with	IN
cord-355413-ls2nud43	250	9	reduced	reduce	VBN
cord-355413-ls2nud43	250	10	NK	NK	NNP
cord-355413-ls2nud43	250	11	cells	cell	NNS
cord-355413-ls2nud43	250	12	in	in	IN
cord-355413-ls2nud43	250	13	the	the	DT
cord-355413-ls2nud43	250	14	CNS	CNS	NNP
cord-355413-ls2nud43	250	15	and	and	CC
cord-355413-ls2nud43	250	16	intact	intact	JJ
cord-355413-ls2nud43	250	17	NK	NK	NNP
cord-355413-ls2nud43	250	18	cells	cell	NNS
cord-355413-ls2nud43	250	19	in	in	IN
cord-355413-ls2nud43	250	20	the	the	DT
cord-355413-ls2nud43	250	21	periphery	periphery	NN
cord-355413-ls2nud43	250	22	developed	develop	VBD
cord-355413-ls2nud43	250	23	their	-PRON-	PRP$
cord-355413-ls2nud43	250	24	wild	wild	JJ
cord-355413-ls2nud43	250	25	-	-	HYPH
cord-355413-ls2nud43	250	26	type	type	NN
cord-355413-ls2nud43	250	27	controls	control	NNS
cord-355413-ls2nud43	250	28	.	.	.
cord-355413-ls2nud43	251	1	Thus	thus	RB
cord-355413-ls2nud43	251	2	,	,	,
cord-355413-ls2nud43	251	3	lack	lack	NN
cord-355413-ls2nud43	251	4	of	of	IN
cord-355413-ls2nud43	251	5	CNS	CNS	NNP
cord-355413-ls2nud43	251	6	NK	NK	NNP
cord-355413-ls2nud43	251	7	cells	cell	NNS
cord-355413-ls2nud43	251	8	alone	alone	RB
cord-355413-ls2nud43	251	9	is	be	VBZ
cord-355413-ls2nud43	251	10	sufficient	sufficient	JJ
cord-355413-ls2nud43	251	11	to	to	TO
cord-355413-ls2nud43	251	12	cause	cause	VB
cord-355413-ls2nud43	251	13	exacerbated	exacerbate	VBN
cord-355413-ls2nud43	251	14	CNS	CNS	NNP
cord-355413-ls2nud43	251	15	inflammation	inflammation	NN
cord-355413-ls2nud43	251	16	and	and	CC
cord-355413-ls2nud43	251	17	autoimmunity	autoimmunity	NN
cord-355413-ls2nud43	251	18	(	(	-LRB-
cord-355413-ls2nud43	251	19	Huang	Huang	NNP
cord-355413-ls2nud43	251	20	et	et	NNP
cord-355413-ls2nud43	251	21	al	al	NNP
cord-355413-ls2nud43	251	22	.	.	NNP
cord-355413-ls2nud43	251	23	,	,	,
cord-355413-ls2nud43	251	24	2006	2006	CD
cord-355413-ls2nud43	251	25	)	)	-RRB-
cord-355413-ls2nud43	251	26	.	.	.
cord-355413-ls2nud43	252	1	It	-PRON-	PRP
cord-355413-ls2nud43	252	2	is	be	VBZ
cord-355413-ls2nud43	252	3	also	also	RB
cord-355413-ls2nud43	252	4	conceivable	conceivable	JJ
cord-355413-ls2nud43	252	5	that	that	DT
cord-355413-ls2nud43	252	6	chemokine	chemokine	NN
cord-355413-ls2nud43	252	7	guided	guide	VBN
cord-355413-ls2nud43	252	8	NK	NK	NNP
cord-355413-ls2nud43	252	9	cell	cell	NN
cord-355413-ls2nud43	252	10	homing	homing	NN
cord-355413-ls2nud43	252	11	to	to	IN
cord-355413-ls2nud43	252	12	CNS	CNS	NNP
cord-355413-ls2nud43	252	13	might	may	MD
cord-355413-ls2nud43	252	14	serve	serve	VB
cord-355413-ls2nud43	252	15	as	as	IN
cord-355413-ls2nud43	252	16	pathway	pathway	NN
cord-355413-ls2nud43	252	17	that	that	WDT
cord-355413-ls2nud43	252	18	can	can	MD
cord-355413-ls2nud43	252	19	be	be	VB
cord-355413-ls2nud43	252	20	therapeutically	therapeutically	RB
cord-355413-ls2nud43	252	21	targeted	target	VBN
cord-355413-ls2nud43	252	22	(	(	-LRB-
cord-355413-ls2nud43	252	23	Figure	figure	NN
cord-355413-ls2nud43	252	24	28.1	28.1	CD
cord-355413-ls2nud43	252	25	)	)	-RRB-
cord-355413-ls2nud43	252	26	.	.	.
cord-355413-ls2nud43	253	1	Infection	infection	NN
cord-355413-ls2nud43	253	2	is	be	VBZ
cord-355413-ls2nud43	253	3	suggested	suggest	VBN
cord-355413-ls2nud43	253	4	to	to	TO
cord-355413-ls2nud43	253	5	play	play	VB
cord-355413-ls2nud43	253	6	a	a	DT
cord-355413-ls2nud43	253	7	role	role	NN
cord-355413-ls2nud43	253	8	triggering	trigger	VBG
cord-355413-ls2nud43	253	9	the	the	DT
cord-355413-ls2nud43	253	10	initiation	initiation	NN
cord-355413-ls2nud43	253	11	of	of	IN
cord-355413-ls2nud43	253	12	MS	MS	NNP
cord-355413-ls2nud43	253	13	in	in	IN
cord-355413-ls2nud43	253	14	some	some	DT
cord-355413-ls2nud43	253	15	patients	patient	NNS
cord-355413-ls2nud43	253	16	(	(	-LRB-
cord-355413-ls2nud43	253	17	Bendelac	Bendelac	NNP
cord-355413-ls2nud43	253	18	and	and	CC
cord-355413-ls2nud43	253	19	Medzhitov	Medzhitov	NNP
cord-355413-ls2nud43	253	20	,	,	,
cord-355413-ls2nud43	253	21	2002	2002	CD
cord-355413-ls2nud43	253	22	;	;	:
cord-355413-ls2nud43	253	23	Pulendran	Pulendran	NNP
cord-355413-ls2nud43	253	24	and	and	CC
cord-355413-ls2nud43	253	25	Ahmed	Ahmed	NNP
cord-355413-ls2nud43	253	26	,	,	,
cord-355413-ls2nud43	253	27	2006	2006	CD
cord-355413-ls2nud43	253	28	;	;	:
cord-355413-ls2nud43	253	29	Shirahata	Shirahata	NNP
cord-355413-ls2nud43	253	30	et	et	NNP
cord-355413-ls2nud43	253	31	al	al	NNP
cord-355413-ls2nud43	253	32	.	.	NNP
cord-355413-ls2nud43	253	33	,	,	,
cord-355413-ls2nud43	253	34	1992	1992	CD
cord-355413-ls2nud43	253	35	)	)	-RRB-
cord-355413-ls2nud43	253	36	.	.	.
cord-355413-ls2nud43	254	1	The	the	DT
cord-355413-ls2nud43	254	2	use	use	NN
cord-355413-ls2nud43	254	3	of	of	IN
cord-355413-ls2nud43	254	4	complete	complete	JJ
cord-355413-ls2nud43	254	5	Freund	Freund	NNP
cord-355413-ls2nud43	254	6	's	's	POS
cord-355413-ls2nud43	254	7	adjuvant	adjuvant	NN
cord-355413-ls2nud43	254	8	in	in	IN
cord-355413-ls2nud43	254	9	the	the	DT
cord-355413-ls2nud43	254	10	induction	induction	NN
cord-355413-ls2nud43	254	11	of	of	IN
cord-355413-ls2nud43	254	12	EAE	EAE	NNP
cord-355413-ls2nud43	254	13	may	may	MD
cord-355413-ls2nud43	254	14	mimic	mimic	VB
cord-355413-ls2nud43	254	15	this	this	DT
cord-355413-ls2nud43	254	16	process	process	NN
cord-355413-ls2nud43	254	17	(	(	-LRB-
cord-355413-ls2nud43	254	18	Fearon	Fearon	NNP
cord-355413-ls2nud43	254	19	and	and	CC
cord-355413-ls2nud43	254	20	Locksley	Locksley	NNP
cord-355413-ls2nud43	254	21	,	,	,
cord-355413-ls2nud43	254	22	1996	1996	CD
cord-355413-ls2nud43	254	23	)	)	-RRB-
cord-355413-ls2nud43	254	24	.	.	.
cord-355413-ls2nud43	255	1	In	in	IN
cord-355413-ls2nud43	255	2	these	these	DT
cord-355413-ls2nud43	255	3	patients	patient	NNS
cord-355413-ls2nud43	255	4	or	or	CC
cord-355413-ls2nud43	255	5	in	in	IN
cord-355413-ls2nud43	255	6	EAE	EAE	NNP
cord-355413-ls2nud43	255	7	animals	animal	NNS
cord-355413-ls2nud43	255	8	,	,	,
cord-355413-ls2nud43	255	9	NK	NK	NNP
cord-355413-ls2nud43	255	10	cells	cell	NNS
cord-355413-ls2nud43	255	11	may	may	MD
cord-355413-ls2nud43	255	12	contribute	contribute	VB
cord-355413-ls2nud43	255	13	to	to	IN
cord-355413-ls2nud43	255	14	the	the	DT
cord-355413-ls2nud43	255	15	demyelination	demyelination	NN
cord-355413-ls2nud43	255	16	through	through	IN
cord-355413-ls2nud43	255	17	bystander	bystander	NN
cord-355413-ls2nud43	255	18	damage	damage	NN
cord-355413-ls2nud43	255	19	while	while	IN
cord-355413-ls2nud43	255	20	controlling	control	VBG
cord-355413-ls2nud43	255	21	the	the	DT
cord-355413-ls2nud43	255	22	infection	infection	NN
cord-355413-ls2nud43	255	23	.	.	.
cord-355413-ls2nud43	256	1	Once	once	IN
cord-355413-ls2nud43	256	2	infection	infection	NN
cord-355413-ls2nud43	256	3	is	be	VBZ
cord-355413-ls2nud43	256	4	controlled	control	VBN
cord-355413-ls2nud43	256	5	,	,	,
cord-355413-ls2nud43	256	6	NK	NK	NNP
cord-355413-ls2nud43	256	7	cells	cell	NNS
cord-355413-ls2nud43	256	8	may	may	MD
cord-355413-ls2nud43	256	9	function	function	VB
cord-355413-ls2nud43	256	10	to	to	TO
cord-355413-ls2nud43	256	11	inhibit	inhibit	VB
cord-355413-ls2nud43	256	12	the	the	DT
cord-355413-ls2nud43	256	13	excessive	excessive	JJ
cord-355413-ls2nud43	256	14	(	(	-LRB-
cord-355413-ls2nud43	256	15	auto	auto	NN
cord-355413-ls2nud43	256	16	)	)	-RRB-
cord-355413-ls2nud43	256	17	immune	immune	JJ
cord-355413-ls2nud43	256	18	responses	response	NNS
cord-355413-ls2nud43	256	19	elicited	elicit	VBN
cord-355413-ls2nud43	256	20	by	by	IN
cord-355413-ls2nud43	256	21	pathogens	pathogen	NNS
cord-355413-ls2nud43	256	22	.	.	.
cord-355413-ls2nud43	257	1	The	the	DT
cord-355413-ls2nud43	257	2	immune	immune	JJ
cord-355413-ls2nud43	257	3	system	system	NN
cord-355413-ls2nud43	257	4	may	may	MD
cord-355413-ls2nud43	257	5	use	use	VB
cord-355413-ls2nud43	257	6	NK	NK	NNP
cord-355413-ls2nud43	257	7	cell	cell	NN
cord-355413-ls2nud43	257	8	as	as	IN
cord-355413-ls2nud43	257	9	a	a	DT
cord-355413-ls2nud43	257	10	versatile	versatile	JJ
cord-355413-ls2nud43	257	11	regulator	regulator	NN
cord-355413-ls2nud43	257	12	to	to	TO
cord-355413-ls2nud43	257	13	tune	tune	VB
cord-355413-ls2nud43	257	14	its	-PRON-	PRP$
cord-355413-ls2nud43	257	15	capacity	capacity	NN
cord-355413-ls2nud43	257	16	in	in	IN
cord-355413-ls2nud43	257	17	combating	combat	VBG
cord-355413-ls2nud43	257	18	infection	infection	NN
cord-355413-ls2nud43	257	19	and	and	CC
cord-355413-ls2nud43	257	20	avoiding	avoid	VBG
cord-355413-ls2nud43	257	21	autoimmunity	autoimmunity	NN
cord-355413-ls2nud43	257	22	.	.	.
cord-355413-ls2nud43	258	1	The	the	DT
cord-355413-ls2nud43	258	2	mechanism	mechanism	NN
cord-355413-ls2nud43	258	3	underlying	underlie	VBG
cord-355413-ls2nud43	258	4	this	this	DT
cord-355413-ls2nud43	258	5	unique	unique	JJ
cord-355413-ls2nud43	258	6	role	role	NN
cord-355413-ls2nud43	258	7	for	for	IN
cord-355413-ls2nud43	258	8	NK	NK	NNP
cord-355413-ls2nud43	258	9	cells	cell	NNS
cord-355413-ls2nud43	258	10	within	within	IN
cord-355413-ls2nud43	258	11	the	the	DT
cord-355413-ls2nud43	258	12	CNS	CNS	NNP
cord-355413-ls2nud43	258	13	during	during	IN
cord-355413-ls2nud43	258	14	EAE	EAE	NNP
cord-355413-ls2nud43	258	15	is	be	VBZ
cord-355413-ls2nud43	258	16	still	still	RB
cord-355413-ls2nud43	258	17	elusive	elusive	JJ
cord-355413-ls2nud43	258	18	.	.	.
cord-355413-ls2nud43	259	1	A	a	DT
cord-355413-ls2nud43	259	2	close	close	JJ
cord-355413-ls2nud43	259	3	survey	survey	NN
cord-355413-ls2nud43	259	4	of	of	IN
cord-355413-ls2nud43	259	5	the	the	DT
cord-355413-ls2nud43	259	6	literature	literature	NN
cord-355413-ls2nud43	259	7	reveals	reveal	VBZ
cord-355413-ls2nud43	259	8	multiple	multiple	JJ
cord-355413-ls2nud43	259	9	steps	step	NNS
cord-355413-ls2nud43	259	10	where	where	WRB
cord-355413-ls2nud43	259	11	NK	NK	NNP
cord-355413-ls2nud43	259	12	cells	cell	NNS
cord-355413-ls2nud43	259	13	can	can	MD
cord-355413-ls2nud43	259	14	regulate	regulate	VB
cord-355413-ls2nud43	259	15	inflammation	inflammation	NN
cord-355413-ls2nud43	259	16	and	and	CC
cord-355413-ls2nud43	259	17	intervene	intervene	VB
cord-355413-ls2nud43	259	18	in	in	IN
cord-355413-ls2nud43	259	19	the	the	DT
cord-355413-ls2nud43	259	20	loss	loss	NN
cord-355413-ls2nud43	259	21	of	of	IN
cord-355413-ls2nud43	259	22	self	self	NN
cord-355413-ls2nud43	259	23	-	-	HYPH
cord-355413-ls2nud43	259	24	tolerance	tolerance	NN
cord-355413-ls2nud43	259	25	.	.	.
cord-355413-ls2nud43	260	1	Importantly	importantly	RB
cord-355413-ls2nud43	260	2	,	,	,
cord-355413-ls2nud43	260	3	the	the	DT
cord-355413-ls2nud43	260	4	findings	finding	NNS
cord-355413-ls2nud43	260	5	also	also	RB
cord-355413-ls2nud43	260	6	caution	caution	VBP
cord-355413-ls2nud43	260	7	against	against	IN
cord-355413-ls2nud43	260	8	inferring	infer	VBG
cord-355413-ls2nud43	260	9	a	a	DT
cord-355413-ls2nud43	260	10	similar	similar	JJ
cord-355413-ls2nud43	260	11	role	role	NN
cord-355413-ls2nud43	260	12	for	for	IN
cord-355413-ls2nud43	260	13	NK	NK	NNP
cord-355413-ls2nud43	260	14	cells	cell	NNS
cord-355413-ls2nud43	260	15	in	in	IN
cord-355413-ls2nud43	260	16	all	all	DT
cord-355413-ls2nud43	260	17	types	type	NNS
cord-355413-ls2nud43	260	18	of	of	IN
cord-355413-ls2nud43	260	19	autoimmune	autoimmune	JJ
cord-355413-ls2nud43	260	20	phenomena	phenomenon	NNS
cord-355413-ls2nud43	260	21	or	or	CC
cord-355413-ls2nud43	260	22	during	during	IN
cord-355413-ls2nud43	260	23	separate	separate	JJ
cord-355413-ls2nud43	260	24	stages	stage	NNS
cord-355413-ls2nud43	260	25	of	of	IN
cord-355413-ls2nud43	260	26	the	the	DT
cord-355413-ls2nud43	260	27	same	same	JJ
cord-355413-ls2nud43	260	28	disease	disease	NN
cord-355413-ls2nud43	260	29	(	(	-LRB-
cord-355413-ls2nud43	260	30	Flodstrom	Flodstrom	NNP
cord-355413-ls2nud43	260	31	et	et	NNP
cord-355413-ls2nud43	260	32	al	al	NNP
cord-355413-ls2nud43	260	33	.	.	NNP
cord-355413-ls2nud43	260	34	,	,	,
cord-355413-ls2nud43	260	35	2002	2002	CD
cord-355413-ls2nud43	260	36	;	;	:
cord-355413-ls2nud43	260	37	Yokoyama	Yokoyama	NNP
cord-355413-ls2nud43	260	38	and	and	CC
cord-355413-ls2nud43	260	39	Plougastel	Plougastel	NNP
cord-355413-ls2nud43	260	40	,	,	,
cord-355413-ls2nud43	260	41	2003	2003	CD
cord-355413-ls2nud43	260	42	)	)	-RRB-
cord-355413-ls2nud43	260	43	.	.	.
cord-355413-ls2nud43	261	1	NK	NK	NNP
cord-355413-ls2nud43	261	2	cells	cell	NNS
cord-355413-ls2nud43	261	3	can	can	MD
cord-355413-ls2nud43	261	4	both	both	DT
cord-355413-ls2nud43	261	5	promote	promote	VB
cord-355413-ls2nud43	261	6	and	and	CC
cord-355413-ls2nud43	261	7	inhibit	inhibit	VB
cord-355413-ls2nud43	261	8	autoreactive	autoreactive	JJ
cord-355413-ls2nud43	261	9	T	t	NN
cord-355413-ls2nud43	261	10	cells	cell	NNS
cord-355413-ls2nud43	261	11	.	.	.
cord-355413-ls2nud43	262	1	These	these	DT
cord-355413-ls2nud43	262	2	possibilities	possibility	NNS
cord-355413-ls2nud43	262	3	have	have	VBP
cord-355413-ls2nud43	262	4	been	be	VBN
cord-355413-ls2nud43	262	5	extensively	extensively	RB
cord-355413-ls2nud43	262	6	reviewed	review	VBN
cord-355413-ls2nud43	262	7	recently	recently	RB
cord-355413-ls2nud43	262	8	(	(	-LRB-
cord-355413-ls2nud43	262	9	Shi	Shi	NNP
cord-355413-ls2nud43	262	10	and	and	CC
cord-355413-ls2nud43	262	11	Van	Van	NNP
cord-355413-ls2nud43	262	12	Kaer	Kaer	NNP
cord-355413-ls2nud43	262	13	,	,	,
cord-355413-ls2nud43	262	14	2006	2006	CD
cord-355413-ls2nud43	262	15	)	)	-RRB-
cord-355413-ls2nud43	262	16	.	.	.
cord-355413-ls2nud43	263	1	The	the	DT
cord-355413-ls2nud43	263	2	specific	specific	JJ
cord-355413-ls2nud43	263	3	CNS	CNS	NNP
cord-355413-ls2nud43	263	4	anatomical	anatomical	JJ
cord-355413-ls2nud43	263	5	location	location	NN
cord-355413-ls2nud43	263	6	,	,	,
cord-355413-ls2nud43	263	7	as	as	IN
cord-355413-ls2nud43	263	8	reflected	reflect	VBN
cord-355413-ls2nud43	263	9	by	by	IN
cord-355413-ls2nud43	263	10	diverse	diverse	JJ
cord-355413-ls2nud43	263	11	CNS	CNS	NNP
cord-355413-ls2nud43	263	12	APCs	apc	NNS
cord-355413-ls2nud43	263	13	and	and	CC
cord-355413-ls2nud43	263	14	multiple	multiple	JJ
cord-355413-ls2nud43	263	15	antigens	antigen	NNS
cord-355413-ls2nud43	263	16	may	may	MD
cord-355413-ls2nud43	263	17	also	also	RB
cord-355413-ls2nud43	263	18	influence	influence	VB
cord-355413-ls2nud43	263	19	the	the	DT
cord-355413-ls2nud43	263	20	outcome	outcome	NN
cord-355413-ls2nud43	263	21	of	of	IN
cord-355413-ls2nud43	263	22	autoimmunity	autoimmunity	NN
cord-355413-ls2nud43	263	23	.	.	.
cord-355413-ls2nud43	264	1	As	as	IN
cord-355413-ls2nud43	264	2	with	with	IN
cord-355413-ls2nud43	264	3	EAE	EAE	NNP
cord-355413-ls2nud43	264	4	,	,	,
cord-355413-ls2nud43	264	5	it	-PRON-	PRP
cord-355413-ls2nud43	264	6	appears	appear	VBZ
cord-355413-ls2nud43	264	7	that	that	IN
cord-355413-ls2nud43	264	8	NK	NK	NNP
cord-355413-ls2nud43	264	9	cells	cell	NNS
cord-355413-ls2nud43	264	10	control	control	VBP
cord-355413-ls2nud43	264	11	T	t	NN
cord-355413-ls2nud43	264	12	cell	cell	NN
cord-355413-ls2nud43	264	13	proliferation	proliferation	NN
cord-355413-ls2nud43	264	14	in	in	IN
cord-355413-ls2nud43	264	15	an	an	DT
cord-355413-ls2nud43	264	16	antigen	antigen	NN
cord-355413-ls2nud43	264	17	non	non	JJ
cord-355413-ls2nud43	264	18	-	-	JJ
cord-355413-ls2nud43	264	19	specific	specific	JJ
cord-355413-ls2nud43	264	20	manner	manner	NN
cord-355413-ls2nud43	264	21	,	,	,
cord-355413-ls2nud43	264	22	both	both	CC
cord-355413-ls2nud43	264	23	in	in	IN
cord-355413-ls2nud43	264	24	the	the	DT
cord-355413-ls2nud43	264	25	periphery	periphery	NN
cord-355413-ls2nud43	264	26	and	and	CC
cord-355413-ls2nud43	264	27	within	within	IN
cord-355413-ls2nud43	264	28	the	the	DT
cord-355413-ls2nud43	264	29	CNS	CNS	NNP
cord-355413-ls2nud43	264	30	(	(	-LRB-
cord-355413-ls2nud43	264	31	Shi	Shi	NNP
cord-355413-ls2nud43	264	32	,	,	,
cord-355413-ls2nud43	264	33	et	et	NNP
cord-355413-ls2nud43	264	34	al	al	NNP
cord-355413-ls2nud43	264	35	.	.	NNP
cord-355413-ls2nud43	264	36	,	,	,
cord-355413-ls2nud43	264	37	unpublished	unpublished	JJ
cord-355413-ls2nud43	264	38	)	)	-RRB-
cord-355413-ls2nud43	264	39	.	.	.
cord-355413-ls2nud43	265	1	Recently	recently	RB
cord-355413-ls2nud43	265	2	,	,	,
cord-355413-ls2nud43	265	3	it	-PRON-	PRP
cord-355413-ls2nud43	265	4	has	have	VBZ
cord-355413-ls2nud43	265	5	been	be	VBN
cord-355413-ls2nud43	265	6	demonstrated	demonstrate	VBN
cord-355413-ls2nud43	265	7	that	that	IN
cord-355413-ls2nud43	265	8	human	human	JJ
cord-355413-ls2nud43	265	9	NK	NK	NNP
cord-355413-ls2nud43	265	10	cells	cell	NNS
cord-355413-ls2nud43	265	11	kill	kill	VBP
cord-355413-ls2nud43	265	12	resting	rest	VBG
cord-355413-ls2nud43	265	13	but	but	CC
cord-355413-ls2nud43	265	14	not	not	RB
cord-355413-ls2nud43	265	15	activated	activate	VBN
cord-355413-ls2nud43	265	16	microglia	microglia	NNS
cord-355413-ls2nud43	265	17	via	via	IN
cord-355413-ls2nud43	265	18	NKG2D	nkg2d	NN
cord-355413-ls2nud43	265	19	-	-	:
cord-355413-ls2nud43	265	20	and	and	CC
cord-355413-ls2nud43	265	21	NKp46-mediated	nkp46-mediated	JJ
cord-355413-ls2nud43	265	22	recognition	recognition	NN
cord-355413-ls2nud43	265	23	(	(	-LRB-
cord-355413-ls2nud43	265	24	Lünemann	Lünemann	NNP
cord-355413-ls2nud43	265	25	et	et	NNP
cord-355413-ls2nud43	265	26	al	al	NNP
cord-355413-ls2nud43	265	27	.	.	NNP
cord-355413-ls2nud43	265	28	,	,	,
cord-355413-ls2nud43	265	29	2008	2008	CD
cord-355413-ls2nud43	265	30	)	)	-RRB-
cord-355413-ls2nud43	265	31	.	.	.
cord-355413-ls2nud43	266	1	This	this	DT
cord-355413-ls2nud43	266	2	study	study	NN
cord-355413-ls2nud43	266	3	emphasizes	emphasize	VBZ
cord-355413-ls2nud43	266	4	the	the	DT
cord-355413-ls2nud43	266	5	potential	potential	JJ
cord-355413-ls2nud43	266	6	importance	importance	NN
cord-355413-ls2nud43	266	7	of	of	IN
cord-355413-ls2nud43	266	8	interactions	interaction	NNS
cord-355413-ls2nud43	266	9	between	between	IN
cord-355413-ls2nud43	266	10	NK	NK	NNP
cord-355413-ls2nud43	266	11	cells	cell	NNS
cord-355413-ls2nud43	266	12	and	and	CC
cord-355413-ls2nud43	266	13	CNS	CNS	NNP
cord-355413-ls2nud43	266	14	resident	resident	JJ
cord-355413-ls2nud43	266	15	APCs	apc	NNS
cord-355413-ls2nud43	266	16	.	.	.
cord-355413-ls2nud43	267	1	However	however	RB
cord-355413-ls2nud43	267	2	,	,	,
cord-355413-ls2nud43	267	3	whether	whether	IN
cord-355413-ls2nud43	267	4	the	the	DT
cord-355413-ls2nud43	267	5	regulatory	regulatory	JJ
cord-355413-ls2nud43	267	6	effects	effect	NNS
cord-355413-ls2nud43	267	7	of	of	IN
cord-355413-ls2nud43	267	8	NK	NK	NNP
cord-355413-ls2nud43	267	9	cells	cell	NNS
cord-355413-ls2nud43	267	10	can	can	MD
cord-355413-ls2nud43	267	11	be	be	VB
cord-355413-ls2nud43	267	12	attributed	attribute	VBN
cord-355413-ls2nud43	267	13	to	to	IN
cord-355413-ls2nud43	267	14	the	the	DT
cord-355413-ls2nud43	267	15	action	action	NN
cord-355413-ls2nud43	267	16	of	of	IN
cord-355413-ls2nud43	267	17	NK	NK	NNP
cord-355413-ls2nud43	267	18	cells	cell	NNS
cord-355413-ls2nud43	267	19	on	on	IN
cord-355413-ls2nud43	267	20	APCs	apc	NNS
cord-355413-ls2nud43	267	21	,	,	,
cord-355413-ls2nud43	267	22	directly	directly	RB
cord-355413-ls2nud43	267	23	on	on	IN
cord-355413-ls2nud43	267	24	T	T	NNP
cord-355413-ls2nud43	267	25	cells	cell	NNS
cord-355413-ls2nud43	267	26	,	,	,
cord-355413-ls2nud43	267	27	or	or	CC
cord-355413-ls2nud43	267	28	both	both	DT
cord-355413-ls2nud43	267	29	,	,	,
cord-355413-ls2nud43	267	30	is	be	VBZ
cord-355413-ls2nud43	267	31	not	not	RB
cord-355413-ls2nud43	267	32	known	know	VBN
cord-355413-ls2nud43	267	33	and	and	CC
cord-355413-ls2nud43	267	34	currently	currently	RB
cord-355413-ls2nud43	267	35	under	under	IN
cord-355413-ls2nud43	267	36	investigation	investigation	NN
cord-355413-ls2nud43	267	37	.	.	.
cord-355413-ls2nud43	268	1	NK	NK	NNP
cord-355413-ls2nud43	268	2	cells	cell	NNS
cord-355413-ls2nud43	268	3	readily	readily	RB
cord-355413-ls2nud43	268	4	accumulate	accumulate	VBP
cord-355413-ls2nud43	268	5	in	in	IN
cord-355413-ls2nud43	268	6	homing	homing	NN
cord-355413-ls2nud43	268	7	to	to	IN
cord-355413-ls2nud43	268	8	CNS	CNS	NNP
cord-355413-ls2nud43	268	9	tissues	tissue	NNS
cord-355413-ls2nud43	268	10	under	under	IN
cord-355413-ls2nud43	268	11	the	the	DT
cord-355413-ls2nud43	268	12	pathophysiological	pathophysiological	JJ
cord-355413-ls2nud43	268	13	situations	situation	NNS
cord-355413-ls2nud43	268	14	.	.	.
cord-355413-ls2nud43	269	1	This	this	DT
cord-355413-ls2nud43	269	2	process	process	NN
cord-355413-ls2nud43	269	3	is	be	VBZ
cord-355413-ls2nud43	269	4	tightly	tightly	RB
cord-355413-ls2nud43	269	5	controlled	control	VBN
cord-355413-ls2nud43	269	6	by	by	IN
cord-355413-ls2nud43	269	7	a	a	DT
cord-355413-ls2nud43	269	8	number	number	NN
cord-355413-ls2nud43	269	9	of	of	IN
cord-355413-ls2nud43	269	10	chemokines	chemokine	NNS
cord-355413-ls2nud43	269	11	and	and	CC
cord-355413-ls2nud43	269	12	chemokine	chemokine	NN
cord-355413-ls2nud43	269	13	receptors	receptor	NNS
cord-355413-ls2nud43	269	14	.	.	.
cord-355413-ls2nud43	270	1	There	there	EX
cord-355413-ls2nud43	270	2	is	be	VBZ
cord-355413-ls2nud43	270	3	ample	ample	JJ
cord-355413-ls2nud43	270	4	of	of	IN
cord-355413-ls2nud43	270	5	evidence	evidence	NN
cord-355413-ls2nud43	270	6	that	that	IN
cord-355413-ls2nud43	270	7	NK	NK	NNP
cord-355413-ls2nud43	270	8	cells	cell	NNS
cord-355413-ls2nud43	270	9	within	within	IN
cord-355413-ls2nud43	270	10	the	the	DT
cord-355413-ls2nud43	270	11	CNS	CNS	NNP
cord-355413-ls2nud43	270	12	contribute	contribute	VBP
cord-355413-ls2nud43	270	13	to	to	IN
cord-355413-ls2nud43	270	14	the	the	DT
cord-355413-ls2nud43	270	15	control	control	NN
cord-355413-ls2nud43	270	16	of	of	IN
cord-355413-ls2nud43	270	17	infections	infection	NNS
cord-355413-ls2nud43	270	18	and	and	CC
cord-355413-ls2nud43	270	19	might	may	MD
cord-355413-ls2nud43	270	20	limit	limit	VB
cord-355413-ls2nud43	270	21	progression	progression	NN
cord-355413-ls2nud43	270	22	of	of	IN
cord-355413-ls2nud43	270	23	certain	certain	JJ
cord-355413-ls2nud43	270	24	tumours	tumour	NNS
cord-355413-ls2nud43	270	25	.	.	.
cord-355413-ls2nud43	271	1	Bystander	bystander	NN
cord-355413-ls2nud43	271	2	neuronal	neuronal	JJ
cord-355413-ls2nud43	271	3	and/or	and/or	CC
cord-355413-ls2nud43	271	4	glial	glial	JJ
cord-355413-ls2nud43	271	5	cell	cell	NN
cord-355413-ls2nud43	271	6	damage	damage	NN
cord-355413-ls2nud43	271	7	can	can	MD
cord-355413-ls2nud43	271	8	occur	occur	VB
cord-355413-ls2nud43	271	9	.	.	.
cord-355413-ls2nud43	272	1	In	in	IN
cord-355413-ls2nud43	272	2	certain	certain	JJ
cord-355413-ls2nud43	272	3	autoimmune	autoimmune	JJ
cord-355413-ls2nud43	272	4	conditions	condition	NNS
cord-355413-ls2nud43	272	5	of	of	IN
cord-355413-ls2nud43	272	6	the	the	DT
cord-355413-ls2nud43	272	7	CNS	CNS	NNP
cord-355413-ls2nud43	272	8	,	,	,
cord-355413-ls2nud43	272	9	NK	NK	NNP
cord-355413-ls2nud43	272	10	cells	cell	NNS
cord-355413-ls2nud43	272	11	appear	appear	VBP
cord-355413-ls2nud43	272	12	to	to	TO
cord-355413-ls2nud43	272	13	have	have	VB
cord-355413-ls2nud43	272	14	an	an	DT
cord-355413-ls2nud43	272	15	inhibitory	inhibitory	JJ
cord-355413-ls2nud43	272	16	role	role	NN
cord-355413-ls2nud43	272	17	.	.	.
cord-355413-ls2nud43	273	1	Activation	activation	NN
cord-355413-ls2nud43	273	2	and	and	CC
cord-355413-ls2nud43	273	3	expansion	expansion	NN
cord-355413-ls2nud43	273	4	of	of	IN
cord-355413-ls2nud43	273	5	NK	NK	NNP
cord-355413-ls2nud43	273	6	cells	cell	NNS
cord-355413-ls2nud43	273	7	through	through	IN
cord-355413-ls2nud43	273	8	engaging	engage	VBG
cord-355413-ls2nud43	273	9	IL-2	IL-2	NNP
cord-355413-ls2nud43	273	10	receptors	receptor	NNS
cord-355413-ls2nud43	273	11	on	on	IN
cord-355413-ls2nud43	273	12	NK	NK	NNP
cord-355413-ls2nud43	273	13	cells	cell	NNS
cord-355413-ls2nud43	273	14	not	not	RB
cord-355413-ls2nud43	273	15	only	only	RB
cord-355413-ls2nud43	273	16	inhibit	inhibit	VBP
cord-355413-ls2nud43	273	17	several	several	JJ
cord-355413-ls2nud43	273	18	CNS	CNS	NNP
cord-355413-ls2nud43	273	19	tumours	tumour	NNS
cord-355413-ls2nud43	273	20	,	,	,
cord-355413-ls2nud43	273	21	but	but	CC
cord-355413-ls2nud43	273	22	also	also	RB
cord-355413-ls2nud43	273	23	might	may	MD
cord-355413-ls2nud43	273	24	slow	slow	VB
cord-355413-ls2nud43	273	25	the	the	DT
cord-355413-ls2nud43	273	26	progression	progression	NN
cord-355413-ls2nud43	273	27	of	of	IN
cord-355413-ls2nud43	273	28	MS	MS	NNP
cord-355413-ls2nud43	273	29	and	and	CC
cord-355413-ls2nud43	273	30	other	other	JJ
cord-355413-ls2nud43	273	31	autoimmune	autoimmune	JJ
cord-355413-ls2nud43	273	32	diseases	disease	NNS
cord-355413-ls2nud43	274	1	(	(	-LRB-
cord-355413-ls2nud43	274	2	Bielekova	Bielekova	NNP
cord-355413-ls2nud43	274	3	et	et	NNP
cord-355413-ls2nud43	274	4	al	al	NNP
cord-355413-ls2nud43	274	5	.	.	NNP
cord-355413-ls2nud43	274	6	,	,	,
cord-355413-ls2nud43	274	7	2006	2006	CD
cord-355413-ls2nud43	274	8	;	;	.
cord-355413-ls2nud43	275	1	Li	Li	NNP
cord-355413-ls2nud43	275	2	et	et	NNP
cord-355413-ls2nud43	275	3	al	al	NNP
cord-355413-ls2nud43	275	4	.	.	NNP
cord-355413-ls2nud43	275	5	,	,	,
cord-355413-ls2nud43	275	6	2005	2005	CD
cord-355413-ls2nud43	275	7	)	)	-RRB-
cord-355413-ls2nud43	275	8	.	.	.
cord-355413-ls2nud43	276	1	Furthermore	furthermore	RB
cord-355413-ls2nud43	276	2	,	,	,
cord-355413-ls2nud43	276	3	the	the	DT
cord-355413-ls2nud43	276	4	ability	ability	NN
cord-355413-ls2nud43	276	5	of	of	IN
cord-355413-ls2nud43	276	6	IFN-	ifn-	DT
cord-355413-ls2nud43	276	7	and	and	CC
cord-355413-ls2nud43	276	8	IFN-	IFN-	NNP
cord-355413-ls2nud43	276	9	to	to	TO
cord-355413-ls2nud43	276	10	ameliorate	ameliorate	VB
cord-355413-ls2nud43	276	11	MS	MS	NNP
cord-355413-ls2nud43	276	12	in	in	IN
cord-355413-ls2nud43	276	13	humans	human	NNS
cord-355413-ls2nud43	276	14	and	and	CC
cord-355413-ls2nud43	276	15	IFN-	ifn-	VBP
cord-355413-ls2nud43	276	16	to	to	TO
cord-355413-ls2nud43	276	17	inhibit	inhibit	VB
cord-355413-ls2nud43	276	18	EAE	EAE	NNP
cord-355413-ls2nud43	276	19	in	in	IN
cord-355413-ls2nud43	276	20	mice	mouse	NNS
cord-355413-ls2nud43	276	21	may	may	MD
cord-355413-ls2nud43	276	22	reflect	reflect	VB
cord-355413-ls2nud43	276	23	the	the	DT
cord-355413-ls2nud43	276	24	ability	ability	NN
cord-355413-ls2nud43	276	25	of	of	IN
cord-355413-ls2nud43	276	26	these	these	DT
cord-355413-ls2nud43	276	27	cytokines	cytokine	NNS
cord-355413-ls2nud43	276	28	to	to	TO
cord-355413-ls2nud43	276	29	transiently	transiently	RB
cord-355413-ls2nud43	276	30	activate	activate	VB
cord-355413-ls2nud43	276	31	NK	NK	NNP
cord-355413-ls2nud43	276	32	-	-	HYPH
cord-355413-ls2nud43	276	33	dependent	dependent	JJ
cord-355413-ls2nud43	276	34	regulatory	regulatory	JJ
cord-355413-ls2nud43	276	35	responses	response	NNS
cord-355413-ls2nud43	276	36	.	.	.
cord-355413-ls2nud43	277	1	However	however	RB
cord-355413-ls2nud43	277	2	,	,	,
cord-355413-ls2nud43	277	3	because	because	IN
cord-355413-ls2nud43	277	4	IFN	IFN	NNP
cord-355413-ls2nud43	277	5	treatment	treatment	NN
cord-355413-ls2nud43	277	6	also	also	RB
cord-355413-ls2nud43	277	7	upregulates	upregulate	VBZ
cord-355413-ls2nud43	277	8	Qa-1	Qa-1	NNP
cord-355413-ls2nud43	277	9	expression	expression	NN
cord-355413-ls2nud43	277	10	on	on	IN
cord-355413-ls2nud43	277	11	T	t	NN
cord-355413-ls2nud43	277	12	cells	cell	NNS
cord-355413-ls2nud43	277	13	(	(	-LRB-
cord-355413-ls2nud43	277	14	Ota	Ota	NNP
cord-355413-ls2nud43	277	15	et	et	FW
cord-355413-ls2nud43	277	16	al	al	NNP
cord-355413-ls2nud43	277	17	.	.	NNP
cord-355413-ls2nud43	277	18	,	,	,
cord-355413-ls2nud43	277	19	2005	2005	CD
cord-355413-ls2nud43	277	20	)	)	-RRB-
cord-355413-ls2nud43	277	21	,	,	,
cord-355413-ls2nud43	277	22	the	the	DT
cord-355413-ls2nud43	277	23	short	short	JJ
cord-355413-ls2nud43	277	24	duration	duration	NN
cord-355413-ls2nud43	277	25	and	and	CC
cord-355413-ls2nud43	277	26	usually	usually	RB
cord-355413-ls2nud43	277	27	modest	modest	JJ
cord-355413-ls2nud43	277	28	nature	nature	NN
cord-355413-ls2nud43	277	29	of	of	IN
cord-355413-ls2nud43	277	30	these	these	DT
cord-355413-ls2nud43	277	31	therapeutic	therapeutic	JJ
cord-355413-ls2nud43	277	32	effects	effect	NNS
cord-355413-ls2nud43	277	33	may	may	MD
cord-355413-ls2nud43	277	34	reflect	reflect	VB
cord-355413-ls2nud43	277	35	a	a	DT
cord-355413-ls2nud43	277	36	Qa-1-dependent	qa-1-dependent	NN
cord-355413-ls2nud43	277	37	decrease	decrease	NN
cord-355413-ls2nud43	277	38	in	in	IN
cord-355413-ls2nud43	277	39	NK	NK	NNP
cord-355413-ls2nud43	277	40	cell	cell	NN
cord-355413-ls2nud43	277	41	activation	activation	NN
cord-355413-ls2nud43	277	42	and	and	CC
cord-355413-ls2nud43	277	43	associated	associate	VBD
cord-355413-ls2nud43	277	44	immunoregulatory	immunoregulatory	JJ
cord-355413-ls2nud43	277	45	activity	activity	NN
cord-355413-ls2nud43	277	46	(	(	-LRB-
cord-355413-ls2nud43	277	47	Lu	Lu	NNP
cord-355413-ls2nud43	277	48	et	et	FW
cord-355413-ls2nud43	277	49	al	al	NNP
cord-355413-ls2nud43	277	50	.	.	NNP
cord-355413-ls2nud43	277	51	,	,	,
cord-355413-ls2nud43	277	52	2007	2007	CD
cord-355413-ls2nud43	277	53	)	)	-RRB-
cord-355413-ls2nud43	277	54	.	.	.
cord-355413-ls2nud43	278	1	Disassociation	disassociation	NN
cord-355413-ls2nud43	278	2	of	of	IN
cord-355413-ls2nud43	278	3	disease	disease	NN
cord-355413-ls2nud43	278	4	-	-	HYPH
cord-355413-ls2nud43	278	5	inhibiting	inhibit	VBG
cord-355413-ls2nud43	278	6	versus	versus	IN
cord-355413-ls2nud43	278	7	diseasepromoting	diseasepromote	VBG
cord-355413-ls2nud43	278	8	effects	effect	NNS
cord-355413-ls2nud43	278	9	of	of	IN
cord-355413-ls2nud43	278	10	NK	NK	NNP
cord-355413-ls2nud43	278	11	cells	cell	NNS
cord-355413-ls2nud43	278	12	is	be	VBZ
cord-355413-ls2nud43	278	13	a	a	DT
cord-355413-ls2nud43	278	14	key	key	NN
cord-355413-ls2nud43	278	15	to	to	IN
cord-355413-ls2nud43	278	16	harnessing	harness	VBG
cord-355413-ls2nud43	278	17	NK	NK	NNP
cord-355413-ls2nud43	278	18	cells	cell	NNS
cord-355413-ls2nud43	278	19	for	for	IN
cord-355413-ls2nud43	278	20	therapeutic	therapeutic	JJ
cord-355413-ls2nud43	278	21	purposes	purpose	NNS
cord-355413-ls2nud43	278	22	.	.	.
cord-355413-ls2nud43	279	1	To	to	TO
cord-355413-ls2nud43	279	2	achieve	achieve	VB
cord-355413-ls2nud43	279	3	this	this	DT
cord-355413-ls2nud43	279	4	goal	goal	NN
cord-355413-ls2nud43	279	5	,	,	,
cord-355413-ls2nud43	279	6	a	a	DT
cord-355413-ls2nud43	279	7	generation	generation	NN
cord-355413-ls2nud43	279	8	of	of	IN
cord-355413-ls2nud43	279	9	genetic	genetic	JJ
cord-355413-ls2nud43	279	10	models	model	NNS
cord-355413-ls2nud43	279	11	with	with	IN
cord-355413-ls2nud43	279	12	selective	selective	JJ
cord-355413-ls2nud43	279	13	NK	NK	NNP
cord-355413-ls2nud43	279	14	cell	cell	NN
cord-355413-ls2nud43	279	15	deficiency	deficiency	NN
cord-355413-ls2nud43	279	16	,	,	,
cord-355413-ls2nud43	279	17	and	and	CC
cord-355413-ls2nud43	279	18	development	development	NN
cord-355413-ls2nud43	279	19	of	of	IN
cord-355413-ls2nud43	279	20	reagents	reagent	NNS
cord-355413-ls2nud43	279	21	(	(	-LRB-
cord-355413-ls2nud43	279	22	antibodies	antibody	NNS
cord-355413-ls2nud43	279	23	)	)	-RRB-
cord-355413-ls2nud43	279	24	for	for	IN
cord-355413-ls2nud43	279	25	visualizing	visualize	VBG
cord-355413-ls2nud43	279	26	subsets	subset	NNS
cord-355413-ls2nud43	279	27	of	of	IN
cord-355413-ls2nud43	279	28	NK	NK	NNP
cord-355413-ls2nud43	279	29	cells	cell	NNS
cord-355413-ls2nud43	279	30	in	in	IN
cord-355413-ls2nud43	279	31	situ	situ	NN
cord-355413-ls2nud43	279	32	will	will	MD
cord-355413-ls2nud43	279	33	be	be	VB
cord-355413-ls2nud43	279	34	necessary	necessary	JJ
cord-355413-ls2nud43	279	35	.	.	.
cord-355413-ls2nud43	280	1	Optimization	optimization	NN
cord-355413-ls2nud43	280	2	of	of	IN
cord-355413-ls2nud43	280	3	methods	method	NNS
cord-355413-ls2nud43	280	4	to	to	TO
cord-355413-ls2nud43	280	5	produce	produce	VB
cord-355413-ls2nud43	280	6	NK	NK	NNP
cord-355413-ls2nud43	280	7	cells	cell	NNS
cord-355413-ls2nud43	280	8	in	in	IN
cord-355413-ls2nud43	280	9	large	large	JJ
cord-355413-ls2nud43	280	10	quantities	quantity	NNS
cord-355413-ls2nud43	280	11	for	for	IN
cord-355413-ls2nud43	280	12	therapeutic	therapeutic	JJ
cord-355413-ls2nud43	280	13	usage	usage	NN
cord-355413-ls2nud43	280	14	is	be	VBZ
cord-355413-ls2nud43	280	15	also	also	RB
cord-355413-ls2nud43	280	16	important	important	JJ
cord-355413-ls2nud43	280	17	.	.	.
cord-355413-ls2nud43	281	1	Clearly	clearly	RB
cord-355413-ls2nud43	281	2	,	,	,
cord-355413-ls2nud43	281	3	understanding	understand	VBG
cord-355413-ls2nud43	281	4	the	the	DT
cord-355413-ls2nud43	281	5	molecular	molecular	JJ
cord-355413-ls2nud43	281	6	signals	signal	NNS
cord-355413-ls2nud43	281	7	and	and	CC
cord-355413-ls2nud43	281	8	pathways	pathway	NNS
cord-355413-ls2nud43	281	9	governing	govern	VBG
cord-355413-ls2nud43	281	10	these	these	DT
cord-355413-ls2nud43	281	11	differential	differential	JJ
cord-355413-ls2nud43	281	12	biological	biological	JJ
cord-355413-ls2nud43	281	13	effects	effect	NNS
cord-355413-ls2nud43	281	14	of	of	IN
cord-355413-ls2nud43	281	15	NK	NK	NNP
cord-355413-ls2nud43	281	16	cells	cell	NNS
cord-355413-ls2nud43	281	17	as	as	RB
cord-355413-ls2nud43	281	18	well	well	RB
cord-355413-ls2nud43	281	19	as	as	IN
cord-355413-ls2nud43	281	20	their	-PRON-	PRP$
cord-355413-ls2nud43	281	21	cross	cross	NN
cord-355413-ls2nud43	281	22	talk	talk	NN
cord-355413-ls2nud43	281	23	with	with	IN
cord-355413-ls2nud43	281	24	T	T	NNP
cord-355413-ls2nud43	281	25	cells	cell	NNS
cord-355413-ls2nud43	281	26	is	be	VBZ
cord-355413-ls2nud43	281	27	key	key	JJ
cord-355413-ls2nud43	281	28	to	to	IN
cord-355413-ls2nud43	281	29	designing	design	VBG
cord-355413-ls2nud43	281	30	NK	NK	NNP
cord-355413-ls2nud43	281	31	cell	cell	NN
cord-355413-ls2nud43	281	32	-	-	HYPH
cord-355413-ls2nud43	281	33	based	base	VBN
cord-355413-ls2nud43	281	34	therapy	therapy	NN
cord-355413-ls2nud43	281	35	for	for	IN
cord-355413-ls2nud43	281	36	CNS	CNS	NNP
cord-355413-ls2nud43	281	37	infections	infection	NNS
cord-355413-ls2nud43	281	38	,	,	,
cord-355413-ls2nud43	281	39	tumours	tumour	NNS
cord-355413-ls2nud43	281	40	and	and	CC
cord-355413-ls2nud43	281	41	autoimmune	autoimmune	JJ
cord-355413-ls2nud43	281	42	diseases	disease	NNS
cord-355413-ls2nud43	281	43	.	.	.
cord-355413-ls2nud43	282	1	Role	role	NN
cord-355413-ls2nud43	282	2	of	of	IN
cord-355413-ls2nud43	282	3	NK	NK	NNP
cord-355413-ls2nud43	282	4	cells	cell	NNS
cord-355413-ls2nud43	282	5	and	and	CC
cord-355413-ls2nud43	282	6	gamma	gamma	NN
cord-355413-ls2nud43	282	7	interferon	interferon	NN
cord-355413-ls2nud43	282	8	in	in	IN
cord-355413-ls2nud43	282	9	transplacental	transplacental	NNP
cord-355413-ls2nud43	282	10	passage	passage	NN
cord-355413-ls2nud43	282	11	of	of	IN
cord-355413-ls2nud43	282	12	Toxoplasma	Toxoplasma	NNP
cord-355413-ls2nud43	282	13	gondii	gondii	NN
cord-355413-ls2nud43	282	14	in	in	IN
cord-355413-ls2nud43	282	15	a	a	DT
cord-355413-ls2nud43	282	16	mouse	mouse	NN
cord-355413-ls2nud43	282	17	model	model	NN
cord-355413-ls2nud43	282	18	of	of	IN
cord-355413-ls2nud43	282	19	primary	primary	JJ
cord-355413-ls2nud43	282	20	infection	infection	NN
cord-355413-ls2nud43	282	21	CCR5	CCR5	NNP
cord-355413-ls2nud43	282	22	deficiency	deficiency	NN
cord-355413-ls2nud43	282	23	drives	drive	VBZ
cord-355413-ls2nud43	282	24	enhanced	enhance	VBD
cord-355413-ls2nud43	282	25	natural	natural	JJ
cord-355413-ls2nud43	282	26	killer	killer	NN
cord-355413-ls2nud43	282	27	cell	cell	NN
cord-355413-ls2nud43	282	28	trafficking	trafficking	NN
cord-355413-ls2nud43	282	29	to	to	IN
cord-355413-ls2nud43	282	30	and	and	CC
cord-355413-ls2nud43	282	31	activation	activation	VB
cord-355413-ls2nud43	282	32	within	within	IN
cord-355413-ls2nud43	282	33	the	the	DT
cord-355413-ls2nud43	282	34	liver	liver	NN
cord-355413-ls2nud43	282	35	in	in	IN
cord-355413-ls2nud43	282	36	murine	murine	JJ
cord-355413-ls2nud43	282	37	T	T	NNP
cord-355413-ls2nud43	282	38	cell	cell	NN
cord-355413-ls2nud43	282	39	-	-	HYPH
cord-355413-ls2nud43	282	40	mediated	mediate	VBN
cord-355413-ls2nud43	282	41	hepatitis	hepatitis	NN
cord-355413-ls2nud43	282	42	NK	NK	NNP
cord-355413-ls2nud43	282	43	cell	cell	NN
cord-355413-ls2nud43	282	44	-	-	HYPH
cord-355413-ls2nud43	282	45	mediated	mediate	VBN
cord-355413-ls2nud43	282	46	immunopathology	immunopathology	NN
cord-355413-ls2nud43	282	47	during	during	IN
cord-355413-ls2nud43	282	48	an	an	DT
cord-355413-ls2nud43	282	49	acute	acute	JJ
cord-355413-ls2nud43	282	50	viral	viral	JJ
cord-355413-ls2nud43	282	51	infection	infection	NN
cord-355413-ls2nud43	282	52	of	of	IN
cord-355413-ls2nud43	282	53	the	the	DT
cord-355413-ls2nud43	282	54	CNS	CNS	NNP
cord-355413-ls2nud43	282	55	Non	Non	NNP
cord-355413-ls2nud43	282	56	-	-	NNP
cord-355413-ls2nud43	282	57	MHC	MHC	NNP
cord-355413-ls2nud43	282	58	-	-	HYPH
cord-355413-ls2nud43	282	59	restricted	restrict	VBN
cord-355413-ls2nud43	282	60	cellmediated	cellmediate	VBN
cord-355413-ls2nud43	282	61	lysis	lysis	NN
cord-355413-ls2nud43	282	62	of	of	IN
cord-355413-ls2nud43	282	63	human	human	JJ
cord-355413-ls2nud43	282	64	oligodendrocytes	oligodendrocyte	NNS
cord-355413-ls2nud43	282	65	in	in	IN
cord-355413-ls2nud43	282	66	vitro	vitro	FW
cord-355413-ls2nud43	282	67	:	:	:
cord-355413-ls2nud43	282	68	relation	relation	NN
cord-355413-ls2nud43	282	69	with	with	IN
cord-355413-ls2nud43	282	70	CD56	CD56	NNP
cord-355413-ls2nud43	282	71	expression	expression	NN
cord-355413-ls2nud43	282	72	Incidence	incidence	NN
cord-355413-ls2nud43	282	73	of	of	IN
cord-355413-ls2nud43	282	74	herpes	herpes	NNP
cord-355413-ls2nud43	282	75	simplex	simplex	NNP
cord-355413-ls2nud43	282	76	virus	virus	NN
cord-355413-ls2nud43	282	77	type	type	NN
cord-355413-ls2nud43	282	78	2	2	CD
cord-355413-ls2nud43	282	79	infection	infection	NN
cord-355413-ls2nud43	282	80	in	in	IN
cord-355413-ls2nud43	282	81	the	the	DT
cord-355413-ls2nud43	282	82	United	United	NNP
cord-355413-ls2nud43	282	83	States	States	NNP
cord-355413-ls2nud43	283	1	The	the	DT
cord-355413-ls2nud43	283	2	molecular	molecular	JJ
cord-355413-ls2nud43	283	3	pathogenesis	pathogenesis	NN
cord-355413-ls2nud43	283	4	or	or	CC
cord-355413-ls2nud43	283	5	Semliki	Semliki	NNP
cord-355413-ls2nud43	283	6	Forest	Forest	NNP
cord-355413-ls2nud43	283	7	virus	virus	NN
cord-355413-ls2nud43	284	1	:	:	:
cord-355413-ls2nud43	284	2	a	a	DT
cord-355413-ls2nud43	284	3	model	model	NN
cord-355413-ls2nud43	284	4	virus	virus	NN
cord-355413-ls2nud43	284	5	made	make	VBD
cord-355413-ls2nud43	284	6	useful	useful	JJ
cord-355413-ls2nud43	284	7	?	?	.
cord-355413-ls2nud43	285	1	Natural	natural	JJ
cord-355413-ls2nud43	285	2	killer	killer	NN
cord-355413-ls2nud43	285	3	cell	cell	NN
cord-355413-ls2nud43	285	4	-	-	HYPH
cord-355413-ls2nud43	285	5	mediated	mediate	VBN
cord-355413-ls2nud43	285	6	lysis	lysis	NN
cord-355413-ls2nud43	285	7	of	of	IN
cord-355413-ls2nud43	285	8	dorsal	dorsal	JJ
cord-355413-ls2nud43	285	9	root	root	NN
cord-355413-ls2nud43	285	10	ganglia	ganglion	NNS
cord-355413-ls2nud43	285	11	neurons	neuron	NNS
cord-355413-ls2nud43	285	12	via	via	IN
cord-355413-ls2nud43	285	13	RAE1/	rae1/	NN
cord-355413-ls2nud43	285	14	NKG2D	NKG2D	NNP
cord-355413-ls2nud43	285	15	interactions	interaction	NNS
cord-355413-ls2nud43	285	16	Direct	direct	JJ
cord-355413-ls2nud43	285	17	NK	NK	NNP
cord-355413-ls2nud43	285	18	cellmediated	cellmediate	VBN
cord-355413-ls2nud43	285	19	lysis	lysis	NN
cord-355413-ls2nud43	285	20	of	of	IN
cord-355413-ls2nud43	285	21	syngenic	syngenic	NNP
cord-355413-ls2nud43	285	22	dorsal	dorsal	JJ
cord-355413-ls2nud43	285	23	root	root	NN
cord-355413-ls2nud43	285	24	ganglia	ganglion	NNS
cord-355413-ls2nud43	285	25	neurons	neuron	NNS
cord-355413-ls2nud43	285	26	in	in	IN
cord-355413-ls2nud43	285	27	vitro	vitro	FW
cord-355413-ls2nud43	285	28	Suppressor	suppressor	NN
cord-355413-ls2nud43	285	29	of	of	IN
cord-355413-ls2nud43	285	30	cytokine	cytokine	NN
cord-355413-ls2nud43	285	31	signaling	signal	VBG
cord-355413-ls2nud43	285	32	1	1	CD
cord-355413-ls2nud43	285	33	expression	expression	NN
cord-355413-ls2nud43	285	34	protects	protect	VBZ
cord-355413-ls2nud43	285	35	oligodendrocytes	oligodendrocyte	NNS
cord-355413-ls2nud43	285	36	from	from	IN
cord-355413-ls2nud43	285	37	the	the	DT
cord-355413-ls2nud43	285	38	deleterious	deleterious	JJ
cord-355413-ls2nud43	285	39	effects	effect	NNS
cord-355413-ls2nud43	285	40	of	of	IN
cord-355413-ls2nud43	285	41	interferongamma	interferongamma	NN
cord-355413-ls2nud43	285	42	A	a	DT
cord-355413-ls2nud43	285	43	proinflammatory	proinflammatory	JJ
cord-355413-ls2nud43	285	44	peptide	peptide	NN
cord-355413-ls2nud43	285	45	from	from	IN
cord-355413-ls2nud43	285	46	herpes	herpes	NNP
cord-355413-ls2nud43	285	47	simplex	simplex	NNP
cord-355413-ls2nud43	285	48	virus	virus	NN
cord-355413-ls2nud43	285	49	type	type	NN
cord-355413-ls2nud43	285	50	2	2	CD
cord-355413-ls2nud43	285	51	glycoprotein	glycoprotein	NN
cord-355413-ls2nud43	285	52	G	g	NN
cord-355413-ls2nud43	285	53	affects	affect	VBZ
cord-355413-ls2nud43	285	54	neutrophil	neutrophil	NN
cord-355413-ls2nud43	285	55	,	,	,
cord-355413-ls2nud43	285	56	monocyte	monocyte	NNP
cord-355413-ls2nud43	285	57	,	,	,
cord-355413-ls2nud43	285	58	and	and	CC
cord-355413-ls2nud43	285	59	NK	NK	NNP
cord-355413-ls2nud43	285	60	cell	cell	NN
cord-355413-ls2nud43	285	61	functions	function	NNS
cord-355413-ls2nud43	285	62	Adjuvants	adjuvant	NNS
cord-355413-ls2nud43	285	63	of	of	IN
cord-355413-ls2nud43	285	64	immunity	immunity	NN
cord-355413-ls2nud43	285	65	:	:	:
cord-355413-ls2nud43	285	66	harnessing	harness	VBG
cord-355413-ls2nud43	285	67	innate	innate	JJ
cord-355413-ls2nud43	285	68	immunity	immunity	NN
cord-355413-ls2nud43	285	69	to	to	TO
cord-355413-ls2nud43	285	70	promote	promote	VB
cord-355413-ls2nud43	285	71	adaptive	adaptive	JJ
cord-355413-ls2nud43	285	72	immunity	immunity	NN
cord-355413-ls2nud43	285	73	Regulatory	Regulatory	NNP
cord-355413-ls2nud43	285	74	CD56(bright	CD56(bright	NNP
cord-355413-ls2nud43	285	75	)	)	-RRB-
cord-355413-ls2nud43	285	76	natural	natural	JJ
cord-355413-ls2nud43	285	77	killer	killer	NN
cord-355413-ls2nud43	285	78	cells	cell	NNS
cord-355413-ls2nud43	285	79	mediate	mediate	VBP
cord-355413-ls2nud43	285	80	immunomodulatory	immunomodulatory	JJ
cord-355413-ls2nud43	285	81	effects	effect	NNS
cord-355413-ls2nud43	285	82	of	of	IN
cord-355413-ls2nud43	285	83	IL-2Ralpha	IL-2Ralpha	NNP
cord-355413-ls2nud43	285	84	-	-	HYPH
cord-355413-ls2nud43	285	85	targeted	target	VBN
cord-355413-ls2nud43	285	86	therapy	therapy	NN
cord-355413-ls2nud43	285	87	(	(	-LRB-
cord-355413-ls2nud43	285	88	daclizumab	daclizumab	NNP
cord-355413-ls2nud43	285	89	)	)	-RRB-
cord-355413-ls2nud43	285	90	in	in	IN
cord-355413-ls2nud43	285	91	multiple	multiple	JJ
cord-355413-ls2nud43	285	92	sclerosis	sclerosis	NN
cord-355413-ls2nud43	285	93	Severe	severe	JJ
cord-355413-ls2nud43	285	94	herpesvirus	herpesvirus	NN
cord-355413-ls2nud43	285	95	infections	infection	NNS
cord-355413-ls2nud43	285	96	in	in	IN
cord-355413-ls2nud43	285	97	an	an	DT
cord-355413-ls2nud43	285	98	adolescent	adolescent	NN
cord-355413-ls2nud43	285	99	without	without	IN
cord-355413-ls2nud43	285	100	natural	natural	JJ
cord-355413-ls2nud43	285	101	killer	killer	NN
cord-355413-ls2nud43	285	102	cells	cell	NNS
cord-355413-ls2nud43	286	1	The	the	DT
cord-355413-ls2nud43	286	2	chemokine	chemokine	NN
cord-355413-ls2nud43	286	3	fractalkine	fractalkine	NN
cord-355413-ls2nud43	286	4	inhibits	inhibit	VBZ
cord-355413-ls2nud43	286	5	Fas	Fas	NNP
cord-355413-ls2nud43	286	6	-	-	HYPH
cord-355413-ls2nud43	286	7	mediated	mediate	VBN
cord-355413-ls2nud43	286	8	cell	cell	NN
cord-355413-ls2nud43	286	9	death	death	NN
cord-355413-ls2nud43	286	10	of	of	IN
cord-355413-ls2nud43	286	11	brain	brain	NN
cord-355413-ls2nud43	286	12	microglia	microglia	VBZ
cord-355413-ls2nud43	286	13	Expression	expression	NN
cord-355413-ls2nud43	286	14	of	of	IN
cord-355413-ls2nud43	286	15	a	a	DT
cord-355413-ls2nud43	286	16	killer	killer	NN
cord-355413-ls2nud43	286	17	cell	cell	NN
cord-355413-ls2nud43	286	18	receptor	receptor	NN
cord-355413-ls2nud43	286	19	-	-	HYPH
cord-355413-ls2nud43	286	20	like	like	JJ
cord-355413-ls2nud43	286	21	gene	gene	NN
cord-355413-ls2nud43	286	22	in	in	IN
cord-355413-ls2nud43	286	23	plastic	plastic	JJ
cord-355413-ls2nud43	286	24	regions	region	NNS
cord-355413-ls2nud43	286	25	of	of	IN
cord-355413-ls2nud43	286	26	the	the	DT
cord-355413-ls2nud43	286	27	central	central	JJ
cord-355413-ls2nud43	286	28	nervous	nervous	JJ
cord-355413-ls2nud43	286	29	system	system	NN
cord-355413-ls2nud43	286	30	Control	Control	NNP
cord-355413-ls2nud43	286	31	of	of	IN
cord-355413-ls2nud43	286	32	microglial	microglial	JJ
cord-355413-ls2nud43	286	33	neurotoxicity	neurotoxicity	NN
cord-355413-ls2nud43	286	34	by	by	IN
cord-355413-ls2nud43	286	35	the	the	DT
cord-355413-ls2nud43	286	36	fractalkine	fractalkine	JJ
cord-355413-ls2nud43	286	37	receptor	receptor	NN
cord-355413-ls2nud43	287	1	Both	both	CC
cord-355413-ls2nud43	287	2	CD133	CD133	NNP
cord-355413-ls2nud43	287	3	and	and	CC
cord-355413-ls2nud43	287	4	CD133-medulloblastoma	CD133-medulloblastoma	NNP
cord-355413-ls2nud43	287	5	cell	cell	NN
cord-355413-ls2nud43	287	6	lines	line	NNS
cord-355413-ls2nud43	287	7	express	express	VBP
cord-355413-ls2nud43	287	8	ligands	ligand	NNS
cord-355413-ls2nud43	287	9	for	for	IN
cord-355413-ls2nud43	287	10	triggering	trigger	VBG
cord-355413-ls2nud43	287	11	NK	NK	NNP
cord-355413-ls2nud43	287	12	receptors	receptor	NNS
cord-355413-ls2nud43	287	13	and	and	CC
cord-355413-ls2nud43	287	14	are	be	VBP
cord-355413-ls2nud43	287	15	susceptible	susceptible	JJ
cord-355413-ls2nud43	287	16	to	to	IN
cord-355413-ls2nud43	287	17	NK	nk	NN
cord-355413-ls2nud43	287	18	-	-	HYPH
cord-355413-ls2nud43	287	19	mediated	mediate	VBN
cord-355413-ls2nud43	287	20	cytotoxicity	cytotoxicity	NN
cord-355413-ls2nud43	287	21	Retinoic	Retinoic	NNP
cord-355413-ls2nud43	287	22	acid	acid	NN
cord-355413-ls2nud43	288	1	early	early	JJ
cord-355413-ls2nud43	288	2	inducible	inducible	JJ
cord-355413-ls2nud43	288	3	genes	gene	NNS
cord-355413-ls2nud43	288	4	define	define	VBP
cord-355413-ls2nud43	288	5	a	a	DT
cord-355413-ls2nud43	288	6	ligand	ligand	NN
cord-355413-ls2nud43	288	7	family	family	NN
cord-355413-ls2nud43	288	8	for	for	IN
cord-355413-ls2nud43	288	9	the	the	DT
cord-355413-ls2nud43	288	10	activating	activate	VBG
cord-355413-ls2nud43	288	11	NKG2D	nkg2d	NN
cord-355413-ls2nud43	288	12	receptor	receptor	NN
cord-355413-ls2nud43	288	13	in	in	IN
cord-355413-ls2nud43	288	14	mice	mice	NN
cord-355413-ls2nud43	288	15	Ligands	Ligands	NNPS
cord-355413-ls2nud43	288	16	for	for	IN
cord-355413-ls2nud43	288	17	the	the	DT
cord-355413-ls2nud43	288	18	murine	murine	JJ
cord-355413-ls2nud43	288	19	NKG2D	nkg2d	CD
cord-355413-ls2nud43	288	20	receptor	receptor	NN
cord-355413-ls2nud43	288	21	:	:	:
cord-355413-ls2nud43	288	22	expression	expression	NN
cord-355413-ls2nud43	288	23	by	by	IN
cord-355413-ls2nud43	288	24	tumor	tumor	NN
cord-355413-ls2nud43	288	25	cells	cell	NNS
cord-355413-ls2nud43	288	26	and	and	CC
cord-355413-ls2nud43	288	27	activation	activation	NN
cord-355413-ls2nud43	288	28	of	of	IN
cord-355413-ls2nud43	288	29	NK	NK	NNP
cord-355413-ls2nud43	288	30	cells	cell	NNS
cord-355413-ls2nud43	288	31	and	and	CC
cord-355413-ls2nud43	288	32	macrophages	macrophage	NNS
cord-355413-ls2nud43	289	1	TGF	TGF	NNP
cord-355413-ls2nud43	289	2	-	-	HYPH
cord-355413-ls2nud43	289	3	beta	beta	NN
cord-355413-ls2nud43	289	4	and	and	CC
cord-355413-ls2nud43	289	5	metalloproteinases	metalloproteinase	NNS
cord-355413-ls2nud43	289	6	differentially	differentially	RB
cord-355413-ls2nud43	289	7	suppress	suppress	VBP
cord-355413-ls2nud43	289	8	NKG2D	nkg2d	NN
cord-355413-ls2nud43	289	9	ligand	ligand	NN
cord-355413-ls2nud43	289	10	surface	surface	NN
cord-355413-ls2nud43	289	11	cells	cell	NNS
cord-355413-ls2nud43	290	1	Intracranial	intracranial	JJ
cord-355413-ls2nud43	290	2	paracrine	paracrine	NN
cord-355413-ls2nud43	290	3	interleukin-2	interleukin-2	IN
cord-355413-ls2nud43	290	4	therapy	therapy	NN
cord-355413-ls2nud43	290	5	stimulates	stimulate	VBZ
cord-355413-ls2nud43	290	6	prolonged	prolonged	JJ
cord-355413-ls2nud43	290	7	antitumor	antitumor	JJ
cord-355413-ls2nud43	290	8	immunity	immunity	NN
cord-355413-ls2nud43	290	9	that	that	WDT
cord-355413-ls2nud43	290	10	extends	extend	VBZ
cord-355413-ls2nud43	290	11	outside	outside	IN
cord-355413-ls2nud43	290	12	the	the	DT
cord-355413-ls2nud43	290	13	central	central	JJ
cord-355413-ls2nud43	290	14	nervous	nervous	JJ
cord-355413-ls2nud43	290	15	system	system	NN
cord-355413-ls2nud43	291	1	The	the	DT
cord-355413-ls2nud43	291	2	instructive	instructive	JJ
cord-355413-ls2nud43	291	3	role	role	NN
cord-355413-ls2nud43	291	4	of	of	IN
cord-355413-ls2nud43	291	5	innate	innate	JJ
cord-355413-ls2nud43	291	6	immunity	immunity	NN
cord-355413-ls2nud43	291	7	in	in	IN
cord-355413-ls2nud43	291	8	the	the	DT
cord-355413-ls2nud43	291	9	acquired	acquire	VBN
cord-355413-ls2nud43	291	10	immune	immune	JJ
cord-355413-ls2nud43	291	11	response	response	NN
cord-355413-ls2nud43	291	12	The	the	DT
cord-355413-ls2nud43	291	13	natural	natural	JJ
cord-355413-ls2nud43	291	14	killer	killer	NN
cord-355413-ls2nud43	291	15	cell	cell	NN
cord-355413-ls2nud43	291	16	-	-	HYPH
cord-355413-ls2nud43	291	17	friend	friend	NN
cord-355413-ls2nud43	291	18	or	or	CC
cord-355413-ls2nud43	291	19	foe	foe	NN
cord-355413-ls2nud43	291	20	in	in	IN
cord-355413-ls2nud43	291	21	autoimmune	autoimmune	JJ
cord-355413-ls2nud43	291	22	disease	disease	NN
cord-355413-ls2nud43	291	23	?	?	.
cord-355413-ls2nud43	292	1	Defective	defective	JJ
cord-355413-ls2nud43	292	2	expression	expression	NN
cord-355413-ls2nud43	292	3	of	of	IN
cord-355413-ls2nud43	292	4	the	the	DT
cord-355413-ls2nud43	292	5	interleukin-2	interleukin-2	NN
cord-355413-ls2nud43	292	6	/	/	SYM
cord-355413-ls2nud43	292	7	interleukin-15	interleukin-15	CD
cord-355413-ls2nud43	292	8	receptor	receptor	NN
cord-355413-ls2nud43	292	9	beta	beta	NN
cord-355413-ls2nud43	292	10	subunit	subunit	NN
cord-355413-ls2nud43	292	11	leads	lead	VBZ
cord-355413-ls2nud43	292	12	to	to	IN
cord-355413-ls2nud43	292	13	a	a	DT
cord-355413-ls2nud43	292	14	natural	natural	JJ
cord-355413-ls2nud43	292	15	killer	killer	NN
cord-355413-ls2nud43	292	16	cell	cell	NN
cord-355413-ls2nud43	292	17	-	-	HYPH
cord-355413-ls2nud43	292	18	deficient	deficient	JJ
cord-355413-ls2nud43	292	19	form	form	NN
cord-355413-ls2nud43	292	20	of	of	IN
cord-355413-ls2nud43	292	21	severe	severe	JJ
cord-355413-ls2nud43	292	22	combined	combine	VBN
cord-355413-ls2nud43	292	23	immunodeficiency	immunodeficiency	NN
cord-355413-ls2nud43	292	24	TAP-1	TAP-1	NNP
cord-355413-ls2nud43	292	25	indirectly	indirectly	RB
cord-355413-ls2nud43	292	26	regulates	regulate	VBZ
cord-355413-ls2nud43	292	27	CD4T	cd4t	NN
cord-355413-ls2nud43	292	28	cell	cell	NN
cord-355413-ls2nud43	292	29	priming	prime	VBG
cord-355413-ls2nud43	292	30	in	in	IN
cord-355413-ls2nud43	292	31	Toxoplasma	toxoplasma	JJ
cord-355413-ls2nud43	292	32	gondii	gondii	NN
cord-355413-ls2nud43	292	33	infection	infection	NN
cord-355413-ls2nud43	292	34	by	by	IN
cord-355413-ls2nud43	292	35	controlling	control	VBG
cord-355413-ls2nud43	292	36	NK	NK	NNP
cord-355413-ls2nud43	292	37	cell	cell	NN
cord-355413-ls2nud43	292	38	IFN	IFN	NNP
cord-355413-ls2nud43	292	39	-	-	HYPH
cord-355413-ls2nud43	292	40	gamma	gamma	NN
cord-355413-ls2nud43	292	41	production	production	NN
cord-355413-ls2nud43	292	42	Epidemiology	epidemiology	NN
cord-355413-ls2nud43	292	43	of	of	IN
cord-355413-ls2nud43	292	44	genital	genital	JJ
cord-355413-ls2nud43	292	45	herpesrecent	herpesrecent	NN
cord-355413-ls2nud43	292	46	advances	advance	VBZ
cord-355413-ls2nud43	292	47	Neuroprotection	Neuroprotection	NNP
cord-355413-ls2nud43	292	48	by	by	IN
cord-355413-ls2nud43	292	49	encephalomyelitis	encephalomyelitis	NN
cord-355413-ls2nud43	292	50	:	:	:
cord-355413-ls2nud43	293	1	rescue	rescue	NN
cord-355413-ls2nud43	293	2	of	of	IN
cord-355413-ls2nud43	293	3	mechanically	mechanically	RB
cord-355413-ls2nud43	293	4	injured	injure	VBN
cord-355413-ls2nud43	293	5	neurons	neuron	NNS
cord-355413-ls2nud43	293	6	and	and	CC
cord-355413-ls2nud43	293	7	neurotrophin	neurotrophin	JJ
cord-355413-ls2nud43	293	8	production	production	NN
cord-355413-ls2nud43	293	9	by	by	IN
cord-355413-ls2nud43	293	10	CNSinfiltrating	cnsinfiltrate	VBG
cord-355413-ls2nud43	293	11	T	T	NNP
cord-355413-ls2nud43	293	12	and	and	CC
cord-355413-ls2nud43	293	13	natural	natural	JJ
cord-355413-ls2nud43	293	14	killer	killer	NN
cord-355413-ls2nud43	293	15	cells	cell	NNS
cord-355413-ls2nud43	293	16	Improved	improve	VBN
cord-355413-ls2nud43	293	17	long	long	JJ
cord-355413-ls2nud43	293	18	term	term	NN
cord-355413-ls2nud43	293	19	survival	survival	NN
cord-355413-ls2nud43	293	20	after	after	IN
cord-355413-ls2nud43	293	21	intracavitary	intracavitary	JJ
cord-355413-ls2nud43	293	22	interleukin-2	interleukin-2	IN
cord-355413-ls2nud43	293	23	and	and	CC
cord-355413-ls2nud43	293	24	lymphokine	lymphokine	NN
cord-355413-ls2nud43	293	25	-	-	HYPH
cord-355413-ls2nud43	293	26	activated	activate	VBN
cord-355413-ls2nud43	293	27	killer	killer	NN
cord-355413-ls2nud43	293	28	cells	cell	NNS
cord-355413-ls2nud43	293	29	for	for	IN
cord-355413-ls2nud43	293	30	adults	adult	NNS
cord-355413-ls2nud43	293	31	with	with	IN
cord-355413-ls2nud43	293	32	recurrent	recurrent	JJ
cord-355413-ls2nud43	293	33	malignant	malignant	JJ
cord-355413-ls2nud43	293	34	glioma	glioma	NN
cord-355413-ls2nud43	293	35	Exogenously	exogenously	NN
cord-355413-ls2nud43	293	36	-	-	HYPH
cord-355413-ls2nud43	293	37	induced	induce	VBN
cord-355413-ls2nud43	293	38	,	,	,
cord-355413-ls2nud43	293	39	natural	natural	JJ
cord-355413-ls2nud43	293	40	killer	killer	NN
cord-355413-ls2nud43	293	41	cell	cell	NN
cord-355413-ls2nud43	293	42	-	-	HYPH
cord-355413-ls2nud43	293	43	mediated	mediate	VBN
cord-355413-ls2nud43	293	44	neuronal	neuronal	JJ
cord-355413-ls2nud43	293	45	killing	killing	NN
cord-355413-ls2nud43	293	46	:	:	:
cord-355413-ls2nud43	293	47	a	a	DT
cord-355413-ls2nud43	293	48	novel	novel	JJ
cord-355413-ls2nud43	293	49	pathogenetic	pathogenetic	JJ
cord-355413-ls2nud43	293	50	mechanism	mechanism	NN
cord-355413-ls2nud43	293	51	Monocyte	Monocyte	NNP
cord-355413-ls2nud43	293	52	chemoattractant	chemoattractant	NN
cord-355413-ls2nud43	293	53	protein-1	protein-1	NNP
cord-355413-ls2nud43	293	54	and	and	CC
cord-355413-ls2nud43	293	55	CCR2	CCR2	NNP
cord-355413-ls2nud43	293	56	interactions	interaction	NNS
cord-355413-ls2nud43	293	57	are	be	VBP
cord-355413-ls2nud43	293	58	required	require	VBN
cord-355413-ls2nud43	293	59	for	for	IN
cord-355413-ls2nud43	293	60	IFN	IFN	NNP
cord-355413-ls2nud43	293	61	-	-	HYPH
cord-355413-ls2nud43	293	62	alpha	alpha	NN
cord-355413-ls2nud43	293	63	/	/	SYM
cord-355413-ls2nud43	293	64	beta	beta	NN
cord-355413-ls2nud43	293	65	-	-	HYPH
cord-355413-ls2nud43	293	66	induced	induce	VBN
cord-355413-ls2nud43	293	67	inflammatory	inflammatory	JJ
cord-355413-ls2nud43	293	68	responses	response	NNS
cord-355413-ls2nud43	293	69	and	and	CC
cord-355413-ls2nud43	293	70	antiviral	antiviral	JJ
cord-355413-ls2nud43	293	71	defense	defense	NN
cord-355413-ls2nud43	293	72	in	in	IN
cord-355413-ls2nud43	293	73	liver	liver	NN
cord-355413-ls2nud43	293	74	Effect	effect	NN
cord-355413-ls2nud43	293	75	of	of	IN
cord-355413-ls2nud43	293	76	immunosuppressive	immunosuppressive	JJ
cord-355413-ls2nud43	293	77	agents	agent	NNS
cord-355413-ls2nud43	293	78	on	on	IN
cord-355413-ls2nud43	293	79	the	the	DT
cord-355413-ls2nud43	293	80	guanethidine	guanethidine	NN
cord-355413-ls2nud43	293	81	-	-	HYPH
cord-355413-ls2nud43	293	82	induced	induce	VBN
cord-355413-ls2nud43	293	83	sympathectomy	sympathectomy	NN
cord-355413-ls2nud43	293	84	in	in	IN
cord-355413-ls2nud43	293	85	athymic	athymic	JJ
cord-355413-ls2nud43	293	86	and	and	CC
cord-355413-ls2nud43	293	87	euthymic	euthymic	JJ
cord-355413-ls2nud43	293	88	rats	rat	NNS
cord-355413-ls2nud43	294	1	The	the	DT
cord-355413-ls2nud43	294	2	neuronal	neuronal	JJ
cord-355413-ls2nud43	294	3	chemokine	chemokine	NN
cord-355413-ls2nud43	294	4	CX3CL1/	CX3CL1/	NNS
cord-355413-ls2nud43	294	5	fractalkine	fractalkine	JJ
cord-355413-ls2nud43	294	6	selectively	selectively	RB
cord-355413-ls2nud43	294	7	recruits	recruit	VBZ
cord-355413-ls2nud43	294	8	NK	NK	NNP
cord-355413-ls2nud43	294	9	cells	cell	NNS
cord-355413-ls2nud43	294	10	that	that	WDT
cord-355413-ls2nud43	294	11	modify	modify	VBP
cord-355413-ls2nud43	294	12	experimental	experimental	JJ
cord-355413-ls2nud43	294	13	autoimmune	autoimmune	JJ
cord-355413-ls2nud43	294	14	encephalomyelitis	encephalomyelitis	NN
cord-355413-ls2nud43	294	15	within	within	IN
cord-355413-ls2nud43	294	16	the	the	DT
cord-355413-ls2nud43	294	17	central	central	JJ
cord-355413-ls2nud43	294	18	nervous	nervous	JJ
cord-355413-ls2nud43	294	19	system	system	NN
cord-355413-ls2nud43	294	20	Cells	cell	NNS
cord-355413-ls2nud43	294	21	and	and	CC
cord-355413-ls2nud43	294	22	cytokines	cytokine	NNS
cord-355413-ls2nud43	294	23	in	in	IN
cord-355413-ls2nud43	294	24	resistance	resistance	NN
cord-355413-ls2nud43	294	25	to	to	IN
cord-355413-ls2nud43	294	26	Toxoplasma	toxoplasma	NN
cord-355413-ls2nud43	294	27	gondii	gondii	NNP
cord-355413-ls2nud43	294	28	Expression	expression	NN
cord-355413-ls2nud43	294	29	and	and	CC
cord-355413-ls2nud43	294	30	regulation	regulation	NN
cord-355413-ls2nud43	294	31	of	of	IN
cord-355413-ls2nud43	294	32	chemokine	chemokine	NN
cord-355413-ls2nud43	294	33	receptors	receptor	NNS
cord-355413-ls2nud43	294	34	in	in	IN
cord-355413-ls2nud43	294	35	human	human	JJ
cord-355413-ls2nud43	294	36	natural	natural	JJ
cord-355413-ls2nud43	294	37	killer	killer	NN
cord-355413-ls2nud43	294	38	cells	cell	NNS
cord-355413-ls2nud43	294	39	Regulation	regulation	NN
cord-355413-ls2nud43	294	40	of	of	IN
cord-355413-ls2nud43	294	41	pulmonary	pulmonary	JJ
cord-355413-ls2nud43	294	42	fibrosis	fibrosis	NN
cord-355413-ls2nud43	294	43	by	by	IN
cord-355413-ls2nud43	294	44	chemokine	chemokine	NN
cord-355413-ls2nud43	294	45	receptor	receptor	NN
cord-355413-ls2nud43	295	1	CXCR3	CXCR3	NNP
cord-355413-ls2nud43	295	2	Requirement	Requirement	NNP
cord-355413-ls2nud43	295	3	of	of	IN
cord-355413-ls2nud43	295	4	non	non	JJ
cord-355413-ls2nud43	295	5	-	-	JJ
cord-355413-ls2nud43	295	6	T	t	JJ
cord-355413-ls2nud43	295	7	cells	cell	NNS
cord-355413-ls2nud43	295	8	that	that	WDT
cord-355413-ls2nud43	295	9	produce	produce	VBP
cord-355413-ls2nud43	295	10	gamma	gamma	NN
cord-355413-ls2nud43	295	11	interferon	interferon	NN
cord-355413-ls2nud43	295	12	for	for	IN
cord-355413-ls2nud43	295	13	prevention	prevention	NN
cord-355413-ls2nud43	295	14	of	of	IN
cord-355413-ls2nud43	295	15	reactivation	reactivation	NN
cord-355413-ls2nud43	295	16	of	of	IN
cord-355413-ls2nud43	295	17	Toxoplasma	toxoplasma	JJ
cord-355413-ls2nud43	295	18	gondii	gondii	NN
cord-355413-ls2nud43	295	19	infection	infection	NN
cord-355413-ls2nud43	295	20	in	in	IN
cord-355413-ls2nud43	295	21	the	the	DT
cord-355413-ls2nud43	295	22	brain	brain	NN
cord-355413-ls2nud43	296	1	Lymphokine	Lymphokine	NNP
cord-355413-ls2nud43	296	2	activated	activate	VBN
cord-355413-ls2nud43	296	3	killer	killer	NN
cord-355413-ls2nud43	296	4	cells	cell	NNS
cord-355413-ls2nud43	296	5	from	from	IN
cord-355413-ls2nud43	296	6	umbilical	umbilical	JJ
cord-355413-ls2nud43	296	7	cord	cord	NN
cord-355413-ls2nud43	296	8	blood	blood	NN
cord-355413-ls2nud43	296	9	show	show	VBP
cord-355413-ls2nud43	296	10	higher	high	JJR
cord-355413-ls2nud43	296	11	antitumor	antitumor	JJ
cord-355413-ls2nud43	296	12	effect	effect	NN
cord-355413-ls2nud43	296	13	against	against	IN
cord-355413-ls2nud43	296	14	anaplastic	anaplastic	JJ
cord-355413-ls2nud43	296	15	astrocytoma	astrocytoma	NN
cord-355413-ls2nud43	296	16	cell	cell	NN
cord-355413-ls2nud43	296	17	line	line	NN
cord-355413-ls2nud43	296	18	(	(	-LRB-
cord-355413-ls2nud43	296	19	U87	U87	NNP
cord-355413-ls2nud43	296	20	)	)	-RRB-
cord-355413-ls2nud43	296	21	and	and	CC
cord-355413-ls2nud43	296	22	medulloblastoma	medulloblastoma	NNP
cord-355413-ls2nud43	296	23	cell	cell	NN
cord-355413-ls2nud43	296	24	line	line	NN
cord-355413-ls2nud43	296	25	(	(	-LRB-
cord-355413-ls2nud43	296	26	TE671	te671	NN
cord-355413-ls2nud43	296	27	)	)	-RRB-
cord-355413-ls2nud43	296	28	than	than	IN
cord-355413-ls2nud43	296	29	lymphokine	lymphokine	NN
cord-355413-ls2nud43	296	30	activated	activate	VBN
cord-355413-ls2nud43	296	31	killer	killer	NN
cord-355413-ls2nud43	296	32	cells	cell	NNS
cord-355413-ls2nud43	296	33	from	from	IN
cord-355413-ls2nud43	296	34	peripheral	peripheral	JJ
cord-355413-ls2nud43	296	35	blood	blood	NN
cord-355413-ls2nud43	296	36	Selective	selective	JJ
cord-355413-ls2nud43	296	37	rejection	rejection	NN
cord-355413-ls2nud43	296	38	of	of	IN
cord-355413-ls2nud43	296	39	H-2-deficient	H-2-deficient	NNP
cord-355413-ls2nud43	296	40	lymphoma	lymphoma	NN
cord-355413-ls2nud43	296	41	variants	variant	NNS
cord-355413-ls2nud43	296	42	suggests	suggest	VBZ
cord-355413-ls2nud43	296	43	alternative	alternative	JJ
cord-355413-ls2nud43	296	44	immune	immune	JJ
cord-355413-ls2nud43	296	45	defence	defence	NN
cord-355413-ls2nud43	296	46	strategy	strategy	NN
cord-355413-ls2nud43	297	1	Overlapping	overlapping	JJ
cord-355413-ls2nud43	297	2	roles	role	NNS
cord-355413-ls2nud43	297	3	of	of	IN
cord-355413-ls2nud43	297	4	P	p	NN
cord-355413-ls2nud43	297	5	-	-	HYPH
cord-355413-ls2nud43	297	6	selectin	selectin	NN
cord-355413-ls2nud43	297	7	and	and	CC
cord-355413-ls2nud43	297	8	alpha	alpha	NN
cord-355413-ls2nud43	297	9	4	4	CD
cord-355413-ls2nud43	297	10	integrin	integrin	JJ
cord-355413-ls2nud43	297	11	to	to	TO
cord-355413-ls2nud43	297	12	recruit	recruit	VB
cord-355413-ls2nud43	297	13	leukocytes	leukocyte	NNS
cord-355413-ls2nud43	297	14	to	to	IN
cord-355413-ls2nud43	297	15	the	the	DT
cord-355413-ls2nud43	297	16	central	central	JJ
cord-355413-ls2nud43	297	17	nervous	nervous	JJ
cord-355413-ls2nud43	297	18	system	system	NN
cord-355413-ls2nud43	297	19	in	in	IN
cord-355413-ls2nud43	297	20	experimental	experimental	JJ
cord-355413-ls2nud43	297	21	autoimmune	autoimmune	JJ
cord-355413-ls2nud43	297	22	encephalomyelitis	encephalomyelitis	NN
cord-355413-ls2nud43	297	23	Interleukin-12	Interleukin-12	VBZ
cord-355413-ls2nud43	297	24	enhances	enhance	VBZ
cord-355413-ls2nud43	297	25	murine	murine	JJ
cord-355413-ls2nud43	297	26	survival	survival	NN
cord-355413-ls2nud43	297	27	against	against	IN
cord-355413-ls2nud43	297	28	acute	acute	JJ
cord-355413-ls2nud43	297	29	toxoplasmosis	toxoplasmosi	NNS
cord-355413-ls2nud43	297	30	CCR5	CCR5	NNP
cord-355413-ls2nud43	297	31	is	be	VBZ
cord-355413-ls2nud43	297	32	essential	essential	JJ
cord-355413-ls2nud43	297	33	for	for	IN
cord-355413-ls2nud43	297	34	NK	NK	NNP
cord-355413-ls2nud43	297	35	cell	cell	NN
cord-355413-ls2nud43	297	36	trafficking	trafficking	NN
cord-355413-ls2nud43	297	37	and	and	CC
cord-355413-ls2nud43	297	38	host	host	NN
cord-355413-ls2nud43	297	39	survival	survival	NN
cord-355413-ls2nud43	297	40	following	follow	VBG
cord-355413-ls2nud43	297	41	Toxoplasma	Toxoplasma	NNP
cord-355413-ls2nud43	297	42	gondii	gondii	NN
cord-355413-ls2nud43	297	43	infection	infection	NN
cord-355413-ls2nud43	298	1	Sphingosine	Sphingosine	NNP
cord-355413-ls2nud43	298	2	1	1	CD
cord-355413-ls2nud43	298	3	phosphate	phosphate	NN
cord-355413-ls2nud43	298	4	induces	induce	VBZ
cord-355413-ls2nud43	298	5	the	the	DT
cord-355413-ls2nud43	298	6	chemotaxis	chemotaxis	NN
cord-355413-ls2nud43	298	7	of	of	IN
cord-355413-ls2nud43	298	8	human	human	JJ
cord-355413-ls2nud43	298	9	natural	natural	JJ
cord-355413-ls2nud43	298	10	killer	killer	NN
cord-355413-ls2nud43	298	11	cells	cell	NNS
cord-355413-ls2nud43	298	12	.	.	.
cord-355413-ls2nud43	299	1	Role	role	NN
cord-355413-ls2nud43	299	2	for	for	IN
cord-355413-ls2nud43	299	3	heterotrimeric	heterotrimeric	NNP
cord-355413-ls2nud43	299	4	G	g	NN
cord-355413-ls2nud43	299	5	proteins	protein	NNS
cord-355413-ls2nud43	299	6	and	and	CC
cord-355413-ls2nud43	299	7	phosphoinositide	phosphoinositide	JJ
cord-355413-ls2nud43	299	8	3	3	CD
cord-355413-ls2nud43	299	9	kinases	kinase	NNS
cord-355413-ls2nud43	299	10	CD4	CD4	NNP
cord-355413-ls2nud43	300	1	CD25	CD25	NNP
cord-355413-ls2nud43	300	2	Tregs	Tregs	NNP
cord-355413-ls2nud43	300	3	and	and	CC
cord-355413-ls2nud43	300	4	NKT	NKT	NNP
cord-355413-ls2nud43	300	5	cells	cell	NNS
cord-355413-ls2nud43	300	6	:	:	:
cord-355413-ls2nud43	300	7	regulators	regulator	NNS
cord-355413-ls2nud43	300	8	regulating	regulate	VBG
cord-355413-ls2nud43	300	9	regulators	regulator	NNS
cord-355413-ls2nud43	300	10	Fractalkine	Fractalkine	NNP
cord-355413-ls2nud43	300	11	mediates	mediate	VBZ
cord-355413-ls2nud43	300	12	natural	natural	JJ
cord-355413-ls2nud43	300	13	killer	killer	NN
cord-355413-ls2nud43	300	14	-	-	HYPH
cord-355413-ls2nud43	300	15	dependent	dependent	JJ
cord-355413-ls2nud43	300	16	antitumor	antitumor	JJ
cord-355413-ls2nud43	300	17	responses	response	NNS
cord-355413-ls2nud43	300	18	in	in	IN
cord-355413-ls2nud43	300	19	vivo	vivo	NN
cord-355413-ls2nud43	300	20	Cutting	cut	VBG
cord-355413-ls2nud43	300	21	edge	edge	NN
cord-355413-ls2nud43	300	22	:	:	:
cord-355413-ls2nud43	300	23	in	in	IN
cord-355413-ls2nud43	300	24	vivo	vivo	NN
cord-355413-ls2nud43	300	25	blockade	blockade	NN
cord-355413-ls2nud43	300	26	of	of	IN
cord-355413-ls2nud43	300	27	human	human	JJ
cord-355413-ls2nud43	300	28	IL-2	IL-2	NNP
cord-355413-ls2nud43	300	29	receptor	receptor	NN
cord-355413-ls2nud43	300	30	induces	induce	VBZ
cord-355413-ls2nud43	300	31	expansion	expansion	NN
cord-355413-ls2nud43	300	32	of	of	IN
cord-355413-ls2nud43	300	33	CD56(bright	CD56(bright	NNP
cord-355413-ls2nud43	300	34	)	)	-RRB-
cord-355413-ls2nud43	300	35	regulatory	regulatory	JJ
cord-355413-ls2nud43	300	36	NK	NK	NNP
cord-355413-ls2nud43	300	37	cells	cell	NNS
cord-355413-ls2nud43	300	38	in	in	IN
cord-355413-ls2nud43	300	39	patients	patient	NNS
cord-355413-ls2nud43	300	40	with	with	IN
cord-355413-ls2nud43	300	41	active	active	JJ
cord-355413-ls2nud43	300	42	uveitis	uveitis	NN
cord-355413-ls2nud43	301	1	In	in	IN
cord-355413-ls2nud43	301	2	search	search	NN
cord-355413-ls2nud43	301	3	of	of	IN
cord-355413-ls2nud43	301	4	the	the	DT
cord-355413-ls2nud43	301	5	'	'	``
cord-355413-ls2nud43	301	6	missing	miss	VBG
cord-355413-ls2nud43	301	7	self	self	NN
cord-355413-ls2nud43	301	8	'	'	''
cord-355413-ls2nud43	301	9	:	:	:
cord-355413-ls2nud43	302	1	MHC	MHC	NNP
cord-355413-ls2nud43	302	2	molecules	molecule	NNS
cord-355413-ls2nud43	302	3	and	and	CC
cord-355413-ls2nud43	302	4	NK	NK	NNP
cord-355413-ls2nud43	302	5	cell	cell	NN
cord-355413-ls2nud43	302	6	recognition	recognition	NN
cord-355413-ls2nud43	302	7	Prospects	prospect	NNS
cord-355413-ls2nud43	302	8	for	for	IN
cord-355413-ls2nud43	302	9	the	the	DT
cord-355413-ls2nud43	302	10	use	use	NN
cord-355413-ls2nud43	302	11	of	of	IN
cord-355413-ls2nud43	302	12	NK	NK	NNP
cord-355413-ls2nud43	302	13	cells	cell	NNS
cord-355413-ls2nud43	302	14	in	in	IN
cord-355413-ls2nud43	302	15	immunotherapy	immunotherapy	NN
cord-355413-ls2nud43	302	16	of	of	IN
cord-355413-ls2nud43	302	17	human	human	JJ
cord-355413-ls2nud43	302	18	cancer	cancer	NN
cord-355413-ls2nud43	302	19	Regulation	Regulation	NNP
cord-355413-ls2nud43	302	20	of	of	IN
cord-355413-ls2nud43	302	21	activated	activate	VBN
cord-355413-ls2nud43	302	22	CD4	CD4	NNP
cord-355413-ls2nud43	302	23	T	T	NNP
cord-355413-ls2nud43	302	24	cells	cell	NNS
cord-355413-ls2nud43	302	25	by	by	IN
cord-355413-ls2nud43	302	26	NK	NK	NNP
cord-355413-ls2nud43	302	27	cells	cell	NNS
cord-355413-ls2nud43	302	28	via	via	IN
cord-355413-ls2nud43	302	29	the	the	DT
cord-355413-ls2nud43	302	30	Qa-1-NKG2A	Qa-1-NKG2A	NNP
cord-355413-ls2nud43	302	31	inhibitory	inhibitory	JJ
cord-355413-ls2nud43	302	32	pathway	pathway	NN
cord-355413-ls2nud43	302	33	iTRAQ	itraq	NN
cord-355413-ls2nud43	302	34	is	be	VBZ
cord-355413-ls2nud43	302	35	a	a	DT
cord-355413-ls2nud43	302	36	useful	useful	JJ
cord-355413-ls2nud43	302	37	method	method	NN
cord-355413-ls2nud43	302	38	to	to	TO
cord-355413-ls2nud43	302	39	screen	screen	NN
cord-355413-ls2nud43	302	40	for	for	IN
cord-355413-ls2nud43	302	41	membrane	membrane	NN
cord-355413-ls2nud43	302	42	-	-	HYPH
cord-355413-ls2nud43	302	43	bound	bind	VBN
cord-355413-ls2nud43	302	44	proteins	protein	NNS
cord-355413-ls2nud43	302	45	differentially	differentially	RB
cord-355413-ls2nud43	302	46	expressed	express	VBN
cord-355413-ls2nud43	302	47	in	in	IN
cord-355413-ls2nud43	302	48	human	human	JJ
cord-355413-ls2nud43	302	49	natural	natural	JJ
cord-355413-ls2nud43	302	50	killer	killer	NN
cord-355413-ls2nud43	302	51	cell	cell	NN
cord-355413-ls2nud43	302	52	types	type	NNS
cord-355413-ls2nud43	302	53	Human	Human	NNP
cord-355413-ls2nud43	302	54	NK	NK	NNP
cord-355413-ls2nud43	302	55	cells	cell	NNS
cord-355413-ls2nud43	302	56	kill	kill	VBP
cord-355413-ls2nud43	302	57	resting	rest	VBG
cord-355413-ls2nud43	302	58	but	but	CC
cord-355413-ls2nud43	302	59	not	not	RB
cord-355413-ls2nud43	302	60	activated	activate	VBN
cord-355413-ls2nud43	302	61	microglia	microglia	NNS
cord-355413-ls2nud43	302	62	via	via	IN
cord-355413-ls2nud43	302	63	NKG2D	nkg2d	NN
cord-355413-ls2nud43	302	64	-	-	:
cord-355413-ls2nud43	302	65	and	and	CC
cord-355413-ls2nud43	303	1	NKp46-mediated	nkp46-mediated	JJ
cord-355413-ls2nud43	303	2	recognition	recognition	NN
cord-355413-ls2nud43	304	1	The	the	DT
cord-355413-ls2nud43	304	2	molecular	molecular	JJ
cord-355413-ls2nud43	304	3	and	and	CC
cord-355413-ls2nud43	304	4	functional	functional	JJ
cord-355413-ls2nud43	304	5	characterization	characterization	NN
cord-355413-ls2nud43	304	6	of	of	IN
cord-355413-ls2nud43	304	7	a	a	DT
cord-355413-ls2nud43	304	8	dominant	dominant	JJ
cord-355413-ls2nud43	304	9	minor	minor	JJ
cord-355413-ls2nud43	304	10	H	h	NN
cord-355413-ls2nud43	304	11	antigen	antigen	NN
cord-355413-ls2nud43	304	12	,	,	,
cord-355413-ls2nud43	304	13	H60	H60	NNP
cord-355413-ls2nud43	304	14	The	the	DT
cord-355413-ls2nud43	304	15	mechanisms	mechanism	NNS
cord-355413-ls2nud43	304	16	controlling	control	VBG
cord-355413-ls2nud43	304	17	NK	NK	NNP
cord-355413-ls2nud43	304	18	cell	cell	NN
cord-355413-ls2nud43	304	19	autoreactivity	autoreactivity	NN
cord-355413-ls2nud43	304	20	in	in	IN
cord-355413-ls2nud43	304	21	TAP2-deficient	tap2-deficient	NN
cord-355413-ls2nud43	304	22	patients	patient	NNS
cord-355413-ls2nud43	304	23	MHV	MHV	NNP
cord-355413-ls2nud43	304	24	infection	infection	NN
cord-355413-ls2nud43	304	25	of	of	IN
cord-355413-ls2nud43	304	26	the	the	DT
cord-355413-ls2nud43	304	27	CNS	CNS	NNP
cord-355413-ls2nud43	304	28	:	:	:
cord-355413-ls2nud43	304	29	mechanisms	mechanism	NNS
cord-355413-ls2nud43	304	30	of	of	IN
cord-355413-ls2nud43	304	31	immunemediated	immunemediated	JJ
cord-355413-ls2nud43	304	32	control	control	NN
cord-355413-ls2nud43	305	1	Induced	induce	VBN
cord-355413-ls2nud43	305	2	recruitment	recruitment	NN
cord-355413-ls2nud43	305	3	of	of	IN
cord-355413-ls2nud43	305	4	NK	NK	NNP
cord-355413-ls2nud43	305	5	cells	cell	NNS
cord-355413-ls2nud43	305	6	to	to	IN
cord-355413-ls2nud43	305	7	lymph	lymph	NN
cord-355413-ls2nud43	305	8	nodes	node	NNS
cord-355413-ls2nud43	305	9	provides	provide	VBZ
cord-355413-ls2nud43	305	10	IFNgamma	IFNgamma	NNP
cord-355413-ls2nud43	305	11	for	for	IN
cord-355413-ls2nud43	305	12	T(H)1	T(H)1	NNP
cord-355413-ls2nud43	305	13	priming	prime	VBG
cord-355413-ls2nud43	305	14	Association	Association	NNP
cord-355413-ls2nud43	305	15	of	of	IN
cord-355413-ls2nud43	305	16	a	a	DT
cord-355413-ls2nud43	305	17	syndrome	syndrome	NN
cord-355413-ls2nud43	305	18	resembling	resemble	VBG
cord-355413-ls2nud43	305	19	Wegener	Wegener	NNP
cord-355413-ls2nud43	305	20	's	's	POS
cord-355413-ls2nud43	305	21	granulomatosis	granulomatosis	NN
cord-355413-ls2nud43	305	22	with	with	IN
cord-355413-ls2nud43	305	23	low	low	JJ
cord-355413-ls2nud43	305	24	surface	surface	NN
cord-355413-ls2nud43	305	25	expression	expression	NN
cord-355413-ls2nud43	305	26	of	of	IN
cord-355413-ls2nud43	305	27	HLA	HLA	NNP
cord-355413-ls2nud43	305	28	class	class	NN
cord-355413-ls2nud43	305	29	-	-	:
cord-355413-ls2nud43	305	30	I	-PRON-	PRP
cord-355413-ls2nud43	305	31	molecules	molecule	NNS
cord-355413-ls2nud43	305	32	NK	NK	NNP
cord-355413-ls2nud43	305	33	cell	cell	NN
cord-355413-ls2nud43	305	34	-	-	HYPH
cord-355413-ls2nud43	305	35	mediated	mediate	VBN
cord-355413-ls2nud43	305	36	lysis	lysis	NN
cord-355413-ls2nud43	305	37	of	of	IN
cord-355413-ls2nud43	305	38	autologous	autologous	JJ
cord-355413-ls2nud43	305	39	human	human	JJ
cord-355413-ls2nud43	305	40	oligodendrocytes	oligodendrocyte	NNS
cord-355413-ls2nud43	305	41	Peripheral	peripheral	JJ
cord-355413-ls2nud43	305	42	neuropathy	neuropathy	NN
cord-355413-ls2nud43	305	43	associated	associate	VBN
cord-355413-ls2nud43	305	44	with	with	IN
cord-355413-ls2nud43	305	45	chronic	chronic	JJ
cord-355413-ls2nud43	305	46	natural	natural	JJ
cord-355413-ls2nud43	305	47	killer	killer	NN
cord-355413-ls2nud43	305	48	cell	cell	NN
cord-355413-ls2nud43	305	49	lymphocytosis	lymphocytosis	NNP
cord-355413-ls2nud43	305	50	T	T	NNP
cord-355413-ls2nud43	305	51	cell	cell	NN
cord-355413-ls2nud43	305	52	-	-	:
cord-355413-ls2nud43	305	53	and	and	CC
cord-355413-ls2nud43	305	54	B	b	NN
cord-355413-ls2nud43	305	55	cell	cell	NN
cord-355413-ls2nud43	305	56	-	-	HYPH
cord-355413-ls2nud43	305	57	independent	independent	JJ
cord-355413-ls2nud43	305	58	adaptive	adaptive	JJ
cord-355413-ls2nud43	305	59	immunity	immunity	NN
cord-355413-ls2nud43	305	60	mediated	mediate	VBN
cord-355413-ls2nud43	305	61	by	by	IN
cord-355413-ls2nud43	305	62	natural	natural	JJ
cord-355413-ls2nud43	305	63	killer	killer	NN
cord-355413-ls2nud43	305	64	cells	cell	NNS
cord-355413-ls2nud43	305	65	IFN	IFN	NNP
cord-355413-ls2nud43	305	66	-	-	HYPH
cord-355413-ls2nud43	305	67	gamma	gamma	NN
cord-355413-ls2nud43	305	68	-	-	HYPH
cord-355413-ls2nud43	305	69	mediated	mediate	VBN
cord-355413-ls2nud43	305	70	negative	negative	JJ
cord-355413-ls2nud43	305	71	feedback	feedback	NN
cord-355413-ls2nud43	305	72	regulation	regulation	NN
cord-355413-ls2nud43	305	73	of	of	IN
cord-355413-ls2nud43	305	74	NKT	NKT	NNP
cord-355413-ls2nud43	305	75	-	-	HYPH
cord-355413-ls2nud43	305	76	cell	cell	NN
cord-355413-ls2nud43	305	77	function	function	NN
cord-355413-ls2nud43	305	78	by	by	IN
cord-355413-ls2nud43	305	79	CD94	CD94	NNP
cord-355413-ls2nud43	305	80	/	/	SYM
cord-355413-ls2nud43	305	81	NKG2	NKG2	NNP
cord-355413-ls2nud43	305	82	Role	role	NN
cord-355413-ls2nud43	305	83	of	of	IN
cord-355413-ls2nud43	305	84	natural	natural	JJ
cord-355413-ls2nud43	305	85	killer	killer	NN
cord-355413-ls2nud43	305	86	cells	cell	NNS
cord-355413-ls2nud43	305	87	as	as	IN
cord-355413-ls2nud43	305	88	immune	immune	JJ
cord-355413-ls2nud43	305	89	effectors	effector	NNS
cord-355413-ls2nud43	305	90	in	in	IN
cord-355413-ls2nud43	305	91	encephalitis	encephalitis	NN
cord-355413-ls2nud43	305	92	and	and	CC
cord-355413-ls2nud43	305	93	demyelination	demyelination	NN
cord-355413-ls2nud43	305	94	induced	induce	VBN
cord-355413-ls2nud43	305	95	by	by	IN
cord-355413-ls2nud43	305	96	Theiler	Theiler	NNP
cord-355413-ls2nud43	305	97	's	's	POS
cord-355413-ls2nud43	305	98	virus	virus	NN
cord-355413-ls2nud43	305	99	Long	long	JJ
cord-355413-ls2nud43	305	100	term	term	NN
cord-355413-ls2nud43	305	101	persistence	persistence	NN
cord-355413-ls2nud43	305	102	of	of	IN
cord-355413-ls2nud43	305	103	herpes	herpes	NNP
cord-355413-ls2nud43	305	104	simplex	simplex	NN
cord-355413-ls2nud43	305	105	virus	virus	NN
cord-355413-ls2nud43	305	106	-	-	HYPH
cord-355413-ls2nud43	305	107	specific	specific	JJ
cord-355413-ls2nud43	305	108	CD8	CD8	NNP
cord-355413-ls2nud43	305	109	CTL	CTL	NNP
cord-355413-ls2nud43	305	110	in	in	IN
cord-355413-ls2nud43	305	111	persons	person	NNS
cord-355413-ls2nud43	305	112	with	with	IN
cord-355413-ls2nud43	305	113	frequently	frequently	RB
cord-355413-ls2nud43	305	114	recurring	recur	VBG
cord-355413-ls2nud43	305	115	genital	genital	JJ
cord-355413-ls2nud43	305	116	herpes	herpe	NNS
cord-355413-ls2nud43	305	117	NK	NK	NNP
cord-355413-ls2nud43	305	118	and	and	CC
cord-355413-ls2nud43	305	119	CD4	CD4	NNP
cord-355413-ls2nud43	305	120	cells	cell	NNS
cord-355413-ls2nud43	305	121	collaborate	collaborate	VBP
cord-355413-ls2nud43	305	122	to	to	TO
cord-355413-ls2nud43	305	123	protect	protect	VB
cord-355413-ls2nud43	305	124	against	against	IN
cord-355413-ls2nud43	305	125	melanoma	melanoma	NN
cord-355413-ls2nud43	305	126	tumor	tumor	NN
cord-355413-ls2nud43	305	127	formation	formation	NN
cord-355413-ls2nud43	305	128	in	in	IN
cord-355413-ls2nud43	305	129	the	the	DT
cord-355413-ls2nud43	305	130	brain	brain	NN
cord-355413-ls2nud43	305	131	Translating	translate	VBG
cord-355413-ls2nud43	305	132	innate	innate	JJ
cord-355413-ls2nud43	305	133	immunity	immunity	NN
cord-355413-ls2nud43	305	134	into	into	IN
cord-355413-ls2nud43	305	135	immunological	immunological	JJ
cord-355413-ls2nud43	305	136	memory	memory	NN
cord-355413-ls2nud43	305	137	:	:	:
cord-355413-ls2nud43	305	138	implications	implication	NNS
cord-355413-ls2nud43	305	139	for	for	IN
cord-355413-ls2nud43	305	140	vaccine	vaccine	NN
cord-355413-ls2nud43	305	141	development	development	NN
cord-355413-ls2nud43	305	142	Three	three	CD
cord-355413-ls2nud43	305	143	or	or	CC
cord-355413-ls2nud43	305	144	more	more	JJR
cord-355413-ls2nud43	305	145	routes	route	NNS
cord-355413-ls2nud43	305	146	for	for	IN
cord-355413-ls2nud43	305	147	leukocyte	leukocyte	NN
cord-355413-ls2nud43	305	148	migration	migration	NN
cord-355413-ls2nud43	305	149	into	into	IN
cord-355413-ls2nud43	305	150	the	the	DT
cord-355413-ls2nud43	305	151	central	central	JJ
cord-355413-ls2nud43	305	152	nervous	nervous	JJ
cord-355413-ls2nud43	305	153	system	system	NN
cord-355413-ls2nud43	305	154	Toxoplasmosis	Toxoplasmosis	NNP
cord-355413-ls2nud43	305	155	Studies	Studies	NNPS
cord-355413-ls2nud43	305	156	on	on	IN
cord-355413-ls2nud43	305	157	a	a	DT
cord-355413-ls2nud43	305	158	murine	murine	JJ
cord-355413-ls2nud43	305	159	model	model	NN
cord-355413-ls2nud43	305	160	of	of	IN
cord-355413-ls2nud43	305	161	congenital	congenital	JJ
cord-355413-ls2nud43	305	162	toxoplasmosis	toxoplasmosis	NN
cord-355413-ls2nud43	305	163	:	:	:
cord-355413-ls2nud43	306	1	vertical	vertical	JJ
cord-355413-ls2nud43	306	2	disease	disease	NN
cord-355413-ls2nud43	306	3	transmission	transmission	NN
cord-355413-ls2nud43	306	4	only	only	RB
cord-355413-ls2nud43	306	5	occurs	occur	VBZ
cord-355413-ls2nud43	306	6	in	in	IN
cord-355413-ls2nud43	306	7	BALB	BALB	NNP
cord-355413-ls2nud43	306	8	/	/	SYM
cord-355413-ls2nud43	306	9	c	c	NN
cord-355413-ls2nud43	306	10	mice	mouse	NNS
cord-355413-ls2nud43	306	11	infected	infect	VBN
cord-355413-ls2nud43	306	12	for	for	IN
cord-355413-ls2nud43	306	13	the	the	DT
cord-355413-ls2nud43	306	14	first	first	JJ
cord-355413-ls2nud43	306	15	time	time	NN
cord-355413-ls2nud43	306	16	during	during	IN
cord-355413-ls2nud43	306	17	pregnancy	pregnancy	NN
cord-355413-ls2nud43	306	18	DA	DA	NNP
cord-355413-ls2nud43	306	19	strain	strain	NN
cord-355413-ls2nud43	306	20	of	of	IN
cord-355413-ls2nud43	306	21	Theiler	Theiler	NNP
cord-355413-ls2nud43	306	22	's	's	POS
cord-355413-ls2nud43	306	23	murine	murine	JJ
cord-355413-ls2nud43	306	24	encephalomyelitis	encephalomyelitis	NN
cord-355413-ls2nud43	306	25	virus	virus	NN
cord-355413-ls2nud43	306	26	induces	induce	VBZ
cord-355413-ls2nud43	306	27	demyelination	demyelination	NN
cord-355413-ls2nud43	306	28	in	in	IN
cord-355413-ls2nud43	306	29	nude	nude	JJ
cord-355413-ls2nud43	306	30	mice	mouse	NNS
cord-355413-ls2nud43	306	31	Mechanism	Mechanism	NNP
cord-355413-ls2nud43	306	32	of	of	IN
cord-355413-ls2nud43	306	33	Theiler	Theiler	NNP
cord-355413-ls2nud43	306	34	's	's	POS
cord-355413-ls2nud43	306	35	virus	virus	NN
cord-355413-ls2nud43	306	36	-	-	HYPH
cord-355413-ls2nud43	306	37	induced	induce	VBN
cord-355413-ls2nud43	306	38	demyelination	demyelination	NN
cord-355413-ls2nud43	306	39	in	in	IN
cord-355413-ls2nud43	306	40	nude	nude	JJ
cord-355413-ls2nud43	306	41	mice	mouse	NNS
cord-355413-ls2nud43	306	42	NKG2D	NKG2D	NNS
cord-355413-ls2nud43	306	43	-	-	HYPH
cord-355413-ls2nud43	306	44	mediated	mediate	VBN
cord-355413-ls2nud43	306	45	cytotoxicity	cytotoxicity	NN
cord-355413-ls2nud43	306	46	toward	toward	IN
cord-355413-ls2nud43	306	47	oligodendrocytes	oligodendrocyte	NNS
cord-355413-ls2nud43	306	48	suggests	suggest	VBZ
cord-355413-ls2nud43	306	49	a	a	DT
cord-355413-ls2nud43	306	50	mechanism	mechanism	NN
cord-355413-ls2nud43	306	51	for	for	IN
cord-355413-ls2nud43	306	52	tissue	tissue	NN
cord-355413-ls2nud43	306	53	injury	injury	NN
cord-355413-ls2nud43	306	54	in	in	IN
cord-355413-ls2nud43	306	55	multiple	multiple	JJ
cord-355413-ls2nud43	306	56	sclerosis	sclerosis	NN
cord-355413-ls2nud43	306	57	Infection	infection	NN
cord-355413-ls2nud43	306	58	of	of	IN
cord-355413-ls2nud43	306	59	mice	mouse	NNS
cord-355413-ls2nud43	306	60	lacking	lack	VBG
cord-355413-ls2nud43	306	61	the	the	DT
cord-355413-ls2nud43	306	62	common	common	JJ
cord-355413-ls2nud43	306	63	cytokine	cytokine	NN
cord-355413-ls2nud43	306	64	receptor	receptor	NN
cord-355413-ls2nud43	306	65	gammachain	gammachain	NN
cord-355413-ls2nud43	306	66	(	(	-LRB-
cord-355413-ls2nud43	306	67	gamma(c	gamma(c	NNP
cord-355413-ls2nud43	306	68	)	)	-RRB-
cord-355413-ls2nud43	306	69	)	)	-RRB-
cord-355413-ls2nud43	306	70	reveals	reveal	VBZ
cord-355413-ls2nud43	306	71	an	an	DT
cord-355413-ls2nud43	306	72	unexpected	unexpected	JJ
cord-355413-ls2nud43	306	73	role	role	NN
cord-355413-ls2nud43	306	74	for	for	IN
cord-355413-ls2nud43	306	75	CD4	CD4	NNP
cord-355413-ls2nud43	306	76	T	T	NNP
cord-355413-ls2nud43	306	77	lymphocytes	lymphocyte	NNS
cord-355413-ls2nud43	306	78	in	in	IN
cord-355413-ls2nud43	306	79	early	early	JJ
cord-355413-ls2nud43	306	80	IFN	IFN	NNP
cord-355413-ls2nud43	306	81	-	-	HYPH
cord-355413-ls2nud43	306	82	gamma	gamma	NN
cord-355413-ls2nud43	306	83	-	-	HYPH
cord-355413-ls2nud43	306	84	dependent	dependent	JJ
cord-355413-ls2nud43	306	85	resistance	resistance	NN
cord-355413-ls2nud43	306	86	to	to	IN
cord-355413-ls2nud43	306	87	Toxoplasma	toxoplasma	NN
cord-355413-ls2nud43	306	88	gondii	gondii	NNP
cord-355413-ls2nud43	306	89	A	a	DT
cord-355413-ls2nud43	306	90	GRA1	GRA1	NNP
cord-355413-ls2nud43	306	91	DNA	dna	NN
cord-355413-ls2nud43	306	92	vaccine	vaccine	NN
cord-355413-ls2nud43	306	93	primes	prime	VBZ
cord-355413-ls2nud43	306	94	cytolytic	cytolytic	JJ
cord-355413-ls2nud43	306	95	CD8(	CD8(	NNS
cord-355413-ls2nud43	306	96	)	)	-RRB-
cord-355413-ls2nud43	306	97	T	t	NN
cord-355413-ls2nud43	306	98	cells	cell	NNS
cord-355413-ls2nud43	306	99	to	to	TO
cord-355413-ls2nud43	306	100	control	control	VB
cord-355413-ls2nud43	306	101	acute	acute	JJ
cord-355413-ls2nud43	306	102	Toxoplasma	toxoplasma	JJ
cord-355413-ls2nud43	306	103	gondii	gondii	NN
cord-355413-ls2nud43	306	104	infection	infection	NN
cord-355413-ls2nud43	307	1	The	the	DT
cord-355413-ls2nud43	307	2	role	role	NN
cord-355413-ls2nud43	307	3	of	of	IN
cord-355413-ls2nud43	307	4	natural	natural	JJ
cord-355413-ls2nud43	307	5	killer	killer	NN
cord-355413-ls2nud43	307	6	cells	cell	NNS
cord-355413-ls2nud43	307	7	in	in	IN
cord-355413-ls2nud43	307	8	host	host	NN
cord-355413-ls2nud43	307	9	-	-	HYPH
cord-355413-ls2nud43	307	10	parasite	parasite	NN
cord-355413-ls2nud43	307	11	interactions	interaction	NNS
cord-355413-ls2nud43	308	1	Innate	innate	JJ
cord-355413-ls2nud43	308	2	immunity	immunity	NN
cord-355413-ls2nud43	308	3	and	and	CC
cord-355413-ls2nud43	308	4	autoimmunity	autoimmunity	NN
cord-355413-ls2nud43	308	5	:	:	:
cord-355413-ls2nud43	308	6	from	from	IN
cord-355413-ls2nud43	308	7	self	self	NN
cord-355413-ls2nud43	308	8	-	-	HYPH
cord-355413-ls2nud43	308	9	protection	protection	NN
cord-355413-ls2nud43	308	10	to	to	IN
cord-355413-ls2nud43	308	11	selfdestruction	selfdestruction	NN
cord-355413-ls2nud43	308	12	Reciprocal	reciprocal	JJ
cord-355413-ls2nud43	308	13	regulation	regulation	NN
cord-355413-ls2nud43	308	14	between	between	IN
cord-355413-ls2nud43	308	15	natural	natural	JJ
cord-355413-ls2nud43	308	16	killer	killer	NN
cord-355413-ls2nud43	308	17	cells	cell	NNS
cord-355413-ls2nud43	308	18	and	and	CC
cord-355413-ls2nud43	308	19	autoreactive	autoreactive	JJ
cord-355413-ls2nud43	308	20	T	t	NN
cord-355413-ls2nud43	308	21	cells	cell	NNS
cord-355413-ls2nud43	309	1	A	a	DT
cord-355413-ls2nud43	309	2	novel	novel	JJ
cord-355413-ls2nud43	309	3	role	role	NN
cord-355413-ls2nud43	309	4	for	for	IN
cord-355413-ls2nud43	309	5	interleukin-18	interleukin-18	NNP
cord-355413-ls2nud43	309	6	in	in	IN
cord-355413-ls2nud43	309	7	human	human	JJ
cord-355413-ls2nud43	309	8	natural	natural	JJ
cord-355413-ls2nud43	309	9	killer	killer	NN
cord-355413-ls2nud43	309	10	cell	cell	NN
cord-355413-ls2nud43	309	11	death	death	NN
cord-355413-ls2nud43	309	12	:	:	:
cord-355413-ls2nud43	309	13	high	high	JJ
cord-355413-ls2nud43	309	14	serum	serum	NN
cord-355413-ls2nud43	309	15	levels	level	NNS
cord-355413-ls2nud43	309	16	and	and	CC
cord-355413-ls2nud43	309	17	low	low	JJ
cord-355413-ls2nud43	309	18	natural	natural	JJ
cord-355413-ls2nud43	309	19	killer	killer	NN
cord-355413-ls2nud43	309	20	cell	cell	NN
cord-355413-ls2nud43	309	21	numbers	number	NNS
cord-355413-ls2nud43	309	22	in	in	IN
cord-355413-ls2nud43	309	23	patients	patient	NNS
cord-355413-ls2nud43	309	24	with	with	IN
cord-355413-ls2nud43	309	25	systemic	systemic	JJ
cord-355413-ls2nud43	309	26	autoimmune	autoimmune	JJ
cord-355413-ls2nud43	309	27	diseases	disease	NNS
cord-355413-ls2nud43	309	28	Growth	Growth	NNP
cord-355413-ls2nud43	309	29	hormone	hormone	NN
cord-355413-ls2nud43	309	30	enhances	enhance	VBZ
cord-355413-ls2nud43	309	31	natural	natural	JJ
cord-355413-ls2nud43	309	32	killer	killer	NN
cord-355413-ls2nud43	309	33	cell	cell	NN
cord-355413-ls2nud43	309	34	activity	activity	NN
cord-355413-ls2nud43	309	35	against	against	IN
cord-355413-ls2nud43	309	36	glioma	glioma	NN
cord-355413-ls2nud43	309	37	Correlation	correlation	NN
cord-355413-ls2nud43	309	38	between	between	IN
cord-355413-ls2nud43	309	39	increased	increase	VBN
cord-355413-ls2nud43	309	40	susceptibility	susceptibility	NN
cord-355413-ls2nud43	309	41	to	to	IN
cord-355413-ls2nud43	309	42	primary	primary	JJ
cord-355413-ls2nud43	309	43	Toxoplasma	toxoplasma	JJ
cord-355413-ls2nud43	309	44	gondii	gondii	NN
cord-355413-ls2nud43	309	45	infection	infection	NN
cord-355413-ls2nud43	309	46	and	and	CC
cord-355413-ls2nud43	309	47	depressed	depressed	JJ
cord-355413-ls2nud43	309	48	production	production	NN
cord-355413-ls2nud43	309	49	of	of	IN
cord-355413-ls2nud43	309	50	gamma	gamma	NN
cord-355413-ls2nud43	309	51	interferon	interferon	NN
cord-355413-ls2nud43	309	52	in	in	IN
cord-355413-ls2nud43	309	53	pregnant	pregnant	JJ
cord-355413-ls2nud43	309	54	mice	mouse	NNS
cord-355413-ls2nud43	310	1	Semliki	Semliki	NNP
cord-355413-ls2nud43	310	2	Forest	Forest	NNP
cord-355413-ls2nud43	310	3	virus	virus	NN
cord-355413-ls2nud43	311	1	I	-PRON-	PRP
cord-355413-ls2nud43	311	2	isolation	isolation	NN
cord-355413-ls2nud43	311	3	and	and	CC
cord-355413-ls2nud43	311	4	pathogenic	pathogenic	JJ
cord-355413-ls2nud43	311	5	properties	property	NNS
cord-355413-ls2nud43	312	1	Human	human	JJ
cord-355413-ls2nud43	312	2	lymphokineactivated	lymphokineactivated	JJ
cord-355413-ls2nud43	312	3	killer	killer	NN
cord-355413-ls2nud43	312	4	cells	cell	NNS
cord-355413-ls2nud43	312	5	are	be	VBP
cord-355413-ls2nud43	312	6	cytotoxic	cytotoxic	JJ
cord-355413-ls2nud43	312	7	against	against	IN
cord-355413-ls2nud43	312	8	cells	cell	NNS
cord-355413-ls2nud43	312	9	infected	infect	VBN
cord-355413-ls2nud43	312	10	with	with	IN
cord-355413-ls2nud43	312	11	Toxoplasma	Toxoplasma	NNP
cord-355413-ls2nud43	312	12	gondii	gondii	NNP
cord-355413-ls2nud43	312	13	Susceptibility	Susceptibility	NNP
cord-355413-ls2nud43	312	14	of	of	IN
cord-355413-ls2nud43	312	15	CCR5-deficient	CCR5-deficient	NNP
cord-355413-ls2nud43	312	16	mice	mouse	NNS
cord-355413-ls2nud43	312	17	to	to	TO
cord-355413-ls2nud43	312	18	genital	genital	VB
cord-355413-ls2nud43	312	19	herpes	herpes	NN
cord-355413-ls2nud43	312	20	simplex	simplex	NN
cord-355413-ls2nud43	312	21	virus	virus	NN
cord-355413-ls2nud43	312	22	type	type	NN
cord-355413-ls2nud43	312	23	2	2	CD
cord-355413-ls2nud43	312	24	is	be	VBZ
cord-355413-ls2nud43	312	25	linked	link	VBN
cord-355413-ls2nud43	312	26	to	to	IN
cord-355413-ls2nud43	312	27	NK	NK	NNP
cord-355413-ls2nud43	312	28	cell	cell	NN
cord-355413-ls2nud43	312	29	mobilization	mobilization	NN
cord-355413-ls2nud43	312	30	Biology	biology	NN
cord-355413-ls2nud43	312	31	of	of	IN
cord-355413-ls2nud43	312	32	natural	natural	JJ
cord-355413-ls2nud43	312	33	killer	killer	NN
cord-355413-ls2nud43	312	34	cells	cell	NNS
cord-355413-ls2nud43	312	35	Reactivation	reactivation	NN
cord-355413-ls2nud43	312	36	of	of	IN
cord-355413-ls2nud43	312	37	genital	genital	JJ
cord-355413-ls2nud43	312	38	herpes	herpes	NN
cord-355413-ls2nud43	312	39	simplex	simplex	NN
cord-355413-ls2nud43	312	40	virus	virus	NN
cord-355413-ls2nud43	312	41	type	type	NN
cord-355413-ls2nud43	312	42	2	2	CD
cord-355413-ls2nud43	312	43	infection	infection	NN
cord-355413-ls2nud43	312	44	in	in	IN
cord-355413-ls2nud43	312	45	asymptomatic	asymptomatic	JJ
cord-355413-ls2nud43	312	46	seropositive	seropositive	JJ
cord-355413-ls2nud43	312	47	persons	person	NNS
cord-355413-ls2nud43	312	48	IFN	IFN	NNP
cord-355413-ls2nud43	312	49	-	-	HYPH
cord-355413-ls2nud43	312	50	gamma	gamma	NN
cord-355413-ls2nud43	312	51	acts	act	NNS
cord-355413-ls2nud43	312	52	on	on	IN
cord-355413-ls2nud43	312	53	T	T	NNP
cord-355413-ls2nud43	312	54	cells	cell	NNS
cord-355413-ls2nud43	312	55	to	to	TO
cord-355413-ls2nud43	312	56	induce	induce	VB
cord-355413-ls2nud43	312	57	NK	NK	NNP
cord-355413-ls2nud43	312	58	cell	cell	NN
cord-355413-ls2nud43	312	59	mobilization	mobilization	NN
cord-355413-ls2nud43	312	60	and	and	CC
cord-355413-ls2nud43	312	61	accumulation	accumulation	NN
cord-355413-ls2nud43	312	62	in	in	IN
cord-355413-ls2nud43	312	63	target	target	NN
cord-355413-ls2nud43	312	64	organs	organ	NNS
cord-355413-ls2nud43	312	65	Expression	expression	NN
cord-355413-ls2nud43	312	66	of	of	IN
cord-355413-ls2nud43	312	67	CXC	CXC	NNP
cord-355413-ls2nud43	312	68	chemokine	chemokine	NN
cord-355413-ls2nud43	312	69	ligand	ligand	NN
cord-355413-ls2nud43	312	70	10	10	CD
cord-355413-ls2nud43	312	71	from	from	IN
cord-355413-ls2nud43	312	72	the	the	DT
cord-355413-ls2nud43	312	73	mouse	mouse	NN
cord-355413-ls2nud43	312	74	hepatitis	hepatitis	NNP
cord-355413-ls2nud43	312	75	virus	virus	NN
cord-355413-ls2nud43	312	76	genome	genome	NN
cord-355413-ls2nud43	312	77	results	result	NNS
cord-355413-ls2nud43	312	78	in	in	IN
cord-355413-ls2nud43	312	79	protection	protection	NN
cord-355413-ls2nud43	312	80	from	from	IN
cord-355413-ls2nud43	312	81	viral	viral	JJ
cord-355413-ls2nud43	312	82	-	-	HYPH
cord-355413-ls2nud43	312	83	induced	induce	VBN
cord-355413-ls2nud43	312	84	neurological	neurological	JJ
cord-355413-ls2nud43	312	85	and	and	CC
cord-355413-ls2nud43	312	86	liver	liver	NN
cord-355413-ls2nud43	312	87	disease	disease	NN
cord-355413-ls2nud43	312	88	Natural	natural	JJ
cord-355413-ls2nud43	312	89	killer	killer	NN
cord-355413-ls2nud43	312	90	cell	cell	NN
cord-355413-ls2nud43	312	91	trafficking	traffic	VBG
cord-355413-ls2nud43	312	92	in	in	IN
cord-355413-ls2nud43	312	93	vivo	vivo	NN
cord-355413-ls2nud43	312	94	requires	require	VBZ
cord-355413-ls2nud43	312	95	a	a	DT
cord-355413-ls2nud43	312	96	dedicated	dedicated	JJ
cord-355413-ls2nud43	312	97	sphingosine	sphingosine	NNP
cord-355413-ls2nud43	312	98	1-phosphate	1-phosphate	CD
cord-355413-ls2nud43	312	99	receptor	receptor	NN
cord-355413-ls2nud43	312	100	Demyelination	Demyelination	NNP
cord-355413-ls2nud43	312	101	induced	induce	VBN
cord-355413-ls2nud43	312	102	by	by	IN
cord-355413-ls2nud43	313	1	murine	murine	JJ
cord-355413-ls2nud43	313	2	hepatitis	hepatitis	NN
cord-355413-ls2nud43	313	3	virus	virus	NN
cord-355413-ls2nud43	313	4	JHM	JHM	NNP
cord-355413-ls2nud43	313	5	strain	strain	NN
cord-355413-ls2nud43	313	6	(	(	-LRB-
cord-355413-ls2nud43	313	7	MHV-4	MHV-4	NNP
cord-355413-ls2nud43	313	8	)	)	-RRB-
cord-355413-ls2nud43	313	9	is	be	VBZ
cord-355413-ls2nud43	313	10	immunologically	immunologically	RB
cord-355413-ls2nud43	313	11	mediated	mediate	VBN
cord-355413-ls2nud43	313	12	T	t	NN
cord-355413-ls2nud43	313	13	cell	cell	NN
cord-355413-ls2nud43	313	14	approach	approach	NN
cord-355413-ls2nud43	313	15	to	to	IN
cord-355413-ls2nud43	313	16	demyelinating	demyelinate	VBG
cord-355413-ls2nud43	313	17	diseases	disease	NNS
cord-355413-ls2nud43	314	1	The	the	DT
cord-355413-ls2nud43	314	2	effects	effect	NNS
cord-355413-ls2nud43	314	3	of	of	IN
cord-355413-ls2nud43	314	4	restraint	restraint	NN
cord-355413-ls2nud43	314	5	stress	stress	NN
cord-355413-ls2nud43	314	6	on	on	IN
cord-355413-ls2nud43	314	7	the	the	DT
cord-355413-ls2nud43	314	8	neuropathogenesis	neuropathogenesis	NN
cord-355413-ls2nud43	314	9	of	of	IN
cord-355413-ls2nud43	314	10	Theiler	Theiler	NNP
cord-355413-ls2nud43	314	11	's	's	POS
cord-355413-ls2nud43	314	12	virus	virus	NN
cord-355413-ls2nud43	314	13	infection	infection	NN
cord-355413-ls2nud43	314	14	II	II	NNP
cord-355413-ls2nud43	314	15	:	:	:
cord-355413-ls2nud43	314	16	NK	NK	NNP
cord-355413-ls2nud43	314	17	cell	cell	NN
cord-355413-ls2nud43	314	18	function	function	NN
cord-355413-ls2nud43	314	19	and	and	CC
cord-355413-ls2nud43	314	20	cytokine	cytokine	NN
cord-355413-ls2nud43	314	21	levels	level	NNS
cord-355413-ls2nud43	314	22	in	in	IN
cord-355413-ls2nud43	314	23	acute	acute	JJ
cord-355413-ls2nud43	314	24	disease	disease	NN
cord-355413-ls2nud43	314	25	Herpes	Herpes	NNP
cord-355413-ls2nud43	314	26	simplex	simplex	NN
cord-355413-ls2nud43	314	27	virus	virus	NN
cord-355413-ls2nud43	314	28	infection	infection	NN
cord-355413-ls2nud43	314	29	HLA	HLA	NNP
cord-355413-ls2nud43	314	30	-	-	HYPH
cord-355413-ls2nud43	314	31	E	e	NN
cord-355413-ls2nud43	314	32	protects	protect	VBZ
cord-355413-ls2nud43	314	33	glioma	glioma	NN
cord-355413-ls2nud43	314	34	cells	cell	NNS
cord-355413-ls2nud43	314	35	from	from	IN
cord-355413-ls2nud43	314	36	NKG2D	nkg2d	NN
cord-355413-ls2nud43	314	37	-	-	HYPH
cord-355413-ls2nud43	314	38	mediated	mediate	VBN
cord-355413-ls2nud43	314	39	immune	immune	JJ
cord-355413-ls2nud43	314	40	responses	response	NNS
cord-355413-ls2nud43	314	41	in	in	IN
cord-355413-ls2nud43	314	42	vitro	vitro	FW
cord-355413-ls2nud43	314	43	:	:	:
cord-355413-ls2nud43	314	44	implications	implication	NNS
cord-355413-ls2nud43	314	45	for	for	IN
cord-355413-ls2nud43	314	46	immune	immune	JJ
cord-355413-ls2nud43	314	47	escape	escape	NN
cord-355413-ls2nud43	314	48	in	in	IN
cord-355413-ls2nud43	314	49	vivo	vivo	NNP
cord-355413-ls2nud43	314	50	Experimental	experimental	JJ
cord-355413-ls2nud43	314	51	appraisal	appraisal	NN
cord-355413-ls2nud43	314	52	of	of	IN
cord-355413-ls2nud43	314	53	the	the	DT
cord-355413-ls2nud43	314	54	lack	lack	NN
cord-355413-ls2nud43	314	55	of	of	IN
cord-355413-ls2nud43	314	56	antitumor	antitumor	JJ
cord-355413-ls2nud43	314	57	natural	natural	JJ
cord-355413-ls2nud43	314	58	killer	killer	NN
cord-355413-ls2nud43	314	59	cell	cell	NN
cord-355413-ls2nud43	314	60	-	-	HYPH
cord-355413-ls2nud43	314	61	mediated	mediate	VBN
cord-355413-ls2nud43	314	62	immunosurveillance	immunosurveillance	NN
cord-355413-ls2nud43	314	63	in	in	IN
cord-355413-ls2nud43	314	64	response	response	NN
cord-355413-ls2nud43	314	65	to	to	IN
cord-355413-ls2nud43	314	66	lymphomas	lymphoma	NNS
cord-355413-ls2nud43	314	67	growing	grow	VBG
cord-355413-ls2nud43	314	68	in	in	IN
cord-355413-ls2nud43	314	69	the	the	DT
cord-355413-ls2nud43	314	70	mouse	mouse	NN
cord-355413-ls2nud43	314	71	brain	brain	NN
cord-355413-ls2nud43	314	72	Immune	Immune	NNP
cord-355413-ls2nud43	314	73	functions	function	NNS
cord-355413-ls2nud43	314	74	encoded	encode	VBN
cord-355413-ls2nud43	314	75	by	by	IN
cord-355413-ls2nud43	314	76	the	the	DT
cord-355413-ls2nud43	314	77	natural	natural	JJ
cord-355413-ls2nud43	314	78	killer	killer	NN
cord-355413-ls2nud43	314	79	gene	gene	NN
cord-355413-ls2nud43	314	80	complex	complex	NN
cord-355413-ls2nud43	314	81	Defective	defective	JJ
cord-355413-ls2nud43	314	82	antitumor	antitumor	JJ
cord-355413-ls2nud43	314	83	responses	response	NNS
cord-355413-ls2nud43	314	84	in	in	IN
cord-355413-ls2nud43	314	85	CX3CR1-deficient	CX3CR1-deficient	NNP
cord-355413-ls2nud43	314	86	mice	mouse	NNS
cord-355413-ls2nud43	314	87	Regulation	Regulation	NNP
cord-355413-ls2nud43	314	88	of	of	IN
cord-355413-ls2nud43	314	89	Experimental	Experimental	NNP
cord-355413-ls2nud43	314	90	Autoimmune	Autoimmune	NNP
cord-355413-ls2nud43	314	91	Encephalomyelitis	Encephalomyelitis	NNP
cord-355413-ls2nud43	314	92	by	by	IN
cord-355413-ls2nud43	314	93	Natural	Natural	NNP
cord-355413-ls2nud43	314	94	Killer	Killer	NNP
cord-355413-ls2nud43	314	95	(	(	-LRB-
cord-355413-ls2nud43	314	96	NK	NK	NNP
cord-355413-ls2nud43	314	97	)	)	-RRB-
cord-355413-ls2nud43	314	98	cells	cell	NNS
cord-355413-ls2nud43	315	1	Mouse	Mouse	NNP
cord-355413-ls2nud43	315	2	hepatitis	hepatitis	NN
cord-355413-ls2nud43	315	3	virus	virus	NN
cord-355413-ls2nud43	315	4	pathogenesis	pathogenesis	NN
cord-355413-ls2nud43	315	5	in	in	IN
cord-355413-ls2nud43	315	6	the	the	DT
cord-355413-ls2nud43	315	7	central	central	JJ
cord-355413-ls2nud43	315	8	nervous	nervous	JJ
cord-355413-ls2nud43	315	9	system	system	NN
cord-355413-ls2nud43	315	10	is	be	VBZ
cord-355413-ls2nud43	315	11	independent	independent	JJ
cord-355413-ls2nud43	315	12	of	of	IN
cord-355413-ls2nud43	315	13	IL-15	IL-15	NNP
cord-355413-ls2nud43	315	14	and	and	CC
cord-355413-ls2nud43	315	15	natural	natural	JJ
cord-355413-ls2nud43	315	16	killer	killer	NN
cord-355413-ls2nud43	315	17	cells	cell	NNS
cord-355413-ls2nud43	316	1	We	-PRON-	PRP
cord-355413-ls2nud43	316	2	thank	thank	VBP
cord-355413-ls2nud43	316	3	Dr	Dr	NNP
cord-355413-ls2nud43	316	4	R.	R.	NNP
cord-355413-ls2nud43	316	5	Liu	Liu	NNP
cord-355413-ls2nud43	316	6	,	,	,
cord-355413-ls2nud43	316	7	Dr	Dr	NNP
cord-355413-ls2nud43	316	8	W.	W.	NNP
cord-355413-ls2nud43	316	9	Piao	Piao	NNP
cord-355413-ls2nud43	316	10	,	,	,
cord-355413-ls2nud43	316	11	and	and	CC
cord-355413-ls2nud43	316	12	Dr.	Dr.	NNP
cord-355413-ls2nud43	316	13	Dayao	Dayao	NNP
cord-355413-ls2nud43	316	14	and	and	CC
cord-355413-ls2nud43	316	15	Ms.	Ms.	NNP
cord-355413-ls2nud43	316	16	Linda	Linda	NNP
cord-355413-ls2nud43	316	17	Swanson	Swanson	NNP
cord-355413-ls2nud43	316	18	for	for	IN
cord-355413-ls2nud43	316	19	their	-PRON-	PRP$
cord-355413-ls2nud43	316	20	wonderful	wonderful	JJ
cord-355413-ls2nud43	316	21	assistance	assistance	NN
cord-355413-ls2nud43	316	22	in	in	IN
cord-355413-ls2nud43	316	23	preparation	preparation	NN
cord-355413-ls2nud43	316	24	of	of	IN
cord-355413-ls2nud43	316	25	this	this	DT
cord-355413-ls2nud43	316	26	chapter	chapter	NN
cord-355413-ls2nud43	316	27	.	.	.
cord-355413-ls2nud43	317	1	The	the	DT
cord-355413-ls2nud43	317	2	Muscular	Muscular	NNP
cord-355413-ls2nud43	317	3	Dystrophy	Dystrophy	NNP
cord-355413-ls2nud43	317	4	Association	Association	NNP
cord-355413-ls2nud43	317	5	,	,	,
cord-355413-ls2nud43	317	6	the	the	DT
cord-355413-ls2nud43	317	7	Barrow	Barrow	NNP
cord-355413-ls2nud43	317	8	Neurological	Neurological	NNP
cord-355413-ls2nud43	317	9	Foundation	Foundation	NNP
cord-355413-ls2nud43	317	10	,	,	,
cord-355413-ls2nud43	317	11	and	and	CC
cord-355413-ls2nud43	317	12	the	the	DT
cord-355413-ls2nud43	317	13	National	National	NNP
cord-355413-ls2nud43	317	14	Institutes	Institutes	NNPS
cord-355413-ls2nud43	317	15	of	of	IN
cord-355413-ls2nud43	317	16	Health	Health	NNP
cord-355413-ls2nud43	317	17	support	support	VBP
cord-355413-ls2nud43	317	18	the	the	DT
cord-355413-ls2nud43	317	19	authors	author	NNS
cord-355413-ls2nud43	317	20	'	'	POS
cord-355413-ls2nud43	317	21	work	work	NN
cord-355413-ls2nud43	317	22	in	in	IN
cord-355413-ls2nud43	317	23	the	the	DT
cord-355413-ls2nud43	317	24	laboratories	laboratory	NNS
cord-355413-ls2nud43	317	25	.	.	.